diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8046a0a978fefab051a74e7a5a6d3ef2ffb1bf7b --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47153eecfad65c2929e81a8dbf6700ccbf6a99c764bba32347d11f2dfdbcb8b8 +size 74946 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9bf20657b50e76a865889cee2953de9b4fe615e8 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 57, + "title": "Average number of proteins per term", + "value": 2.8421052631578947 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9e9596e9a74fe6d8ad02f0d5890d8b82fbcc6da5 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..06fc47054bbad7a1b17a4b84fe7ed9258e0f873d --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tyrosine-protein kinase, active site [IPR008266] 0.4354388261890782 0.3171591682402465 0.7511228307125433 1.0 1.0 4 Q13308 1 +Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.3811821471652655 0.1073568508414267 0.9145058846459873 1.0 1.0 3 Q9UBT2,P22314 2 +Malate dehydrogenase, active site [IPR001252] 0.558335845643644 0.0793705603324239 0.9367378842001988 1.0 1.0 2 P40925 1 +Thiolase, acyl-enzyme intermediate active site [IPR020615] 0.2705054137289838 0.0549412122481533 0.956185298818148 1.0 1.0 5 P55084 1 +ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.4579439252336297 0.0280381678116301 0.9776317095919912 1.0 1.0 2 P53396 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e5b7ba4269e048b976723c3065bfb1ce7fe08989 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP3", "CDC42BPB", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK6", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EIF2AK4", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "IKBKB", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK3", "MARK1", "MARK2", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "UMPS", "VRK1", "VRK2", "WNK1", "WNK2"], "leading_proteins": ["ACLY", "HADHB", "MDH1", "PTK7", "UBA1", "UBA2"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..53e4cd563ba9192b94d21c676871a6820e4cd412 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c3323cf1a0364460b66882aa782527472a6b21bce782778216566f86f53514f +size 74949 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..04750f767e86f38d8ff246e88ae0c17ecf24336f --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +IQ motif, EF-hand binding site [IPR000048] 1 10 1.9991211442111632 0.0455952478838388 4.902912621359223 10.79368932038835 -0.2273048691062784 0.5134620963427197 2.787853554074696 2.339749173467172 1.002129759133213 0.3214407723554939 0.1788224008957527 0.0583817580096799 0.257029649424805 0.3125474900600543 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..118fb3f6cb541488cb5e7c0b8546729dc8664a89 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 4.903225806451613 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..850edfbba33153e1b2a91df3f2e3ebbcb757d02c --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f721b77899b47afc0e066bdee370a00bf1b5b6ed --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Biotin-binding site [IPR001882] 0.9511262130285696 2.314303051587425 0.0206511045284552 0.4763265288182689 0.353363171099751 4 Q96RQ3,P05165 2 +IQ motif, EF-hand binding site [IPR000048] 0.6739392186566492 1.9991211442111632 0.0455952478838388 0.7646520685409899 0.353363171099751 10 Q92614 1 +2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016] 0.7895691699576444 1.4029613434105748 0.1606283665948837 0.9956088028905454 0.5161964643593681 3 P10515 1 +Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578] 0.6445583358456399 0.1852857205735227 0.8530049374463877 1.0 0.9918845213372552 2 Q9Y617 1 +Inositol monophosphatase, metal-binding site [IPR020583] 0.5203497135966108 0.0525336046167749 0.958103519680748 1.0 0.9918845213372552 2 P29218 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a08dcf296727458413d1ba5356776122e9a7c901 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "APEX1", "APOBEC3C", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK4", "CDK5", "CDK6", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EIF2AK4", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MARK1", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["DLAT", "IMPA1", "MCCC1", "MYO18A", "PCCA", "PSAT1"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..3b258345e48d9bcd4cd3996c066ef1b8b103a9d3 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c3a426632562b41587a2c2c6aff7c9ee23d46e0a --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bbe10ad5f82c647daa65d5556f364a2cb0e0ee61ade676f2520b8ecac7d71f36 +size 197414 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f6bb3eac1ddc1177f0bfa12e2c3a7863a971bb7e --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "1": "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "2": "WD40 repeat, conserved site [IPR019775]", "3": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "4": "Chaperonin TCP-1, conserved site [IPR002194]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b79bf4090b87be57b9655bf841710e42b457db32 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c824a11e295dbf6144cfd3fcd89802b03343f1e00954c1b663f0dec1c69df4fb +size 139677 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..753d56f38b4affcb9d34e0160121e1698be35fb9 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71ddb9cd79d98405848aaa77398b870127a3d32115c08019be55e63c40905e0b +size 147774 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..6013e0d677d68e2a9b6aa0523c1229baac7e92c3 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9866b3435f2e4f8860bc53ded219b59bdde36c16a89f8f098b55352f46ff3504 +size 156364 diff --git a/interpro_conserved_site/basic/plot_3.png b/interpro_conserved_site/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..865b230855bce7aac1b6bb920be2a88ae66bdf9a --- /dev/null +++ b/interpro_conserved_site/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eaec7b1ded6e194a18ae5a98674e69ec9a93776fb512d391d47cefdee0870487 +size 145939 diff --git a/interpro_conserved_site/basic/plot_4.png b/interpro_conserved_site/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..7ac2b2e1b68eb40f51851aac164b57cd860760e7 --- /dev/null +++ b/interpro_conserved_site/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:664299ed559b165669c4c0fdeb79d3d4d69a837a7675200a05a7692c6ec55b1f +size 141825 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c8cbce1cd6d36777ff0de8970d6cb3fd325e0c19 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2b0e4a708334abb0cf414a2d44ec9f473981b9f642530e4b88b2a8fc5734bbb5 +size 81838 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a5ad0cc6383997bb9b194f40bb8ecfee3083b90e --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 5 10 2.166211781185664 0.0302950072787897 4.951456310679611 9.776699029126211 -0.8483999101163021 0.4005956075506935 2.187247420210493 1.8164942167575489 0.9035429813719144 0.3144938579483745 1.0 1.0 0.3279997416386323 0.0064898601794518 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fa5310b4b15f3b558fac1d098f68751c505e39df --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 274, + "title": "Average number of proteins per term", + "value": 2.7846715328467155 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f5837eb61059b74051c8671512eeaabf888aad86 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f71b8c5174a15a41dcbb3eec013870d86005c2e3 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,42 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 0.7070090472007174 2.1662117811856634 0.0302950072787897 0.9997815967598348 0.5989741698384367 10 Q9Y3C6,Q9UNP9,P30405,Q9H2H8,P45877 5 +FERM conserved site [IPR019747] 0.7122660638577294 1.7907053504780777 0.0733405906633009 0.9999999991367864 0.5989741698384367 7 Q9HCM4,O43491 2 +Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.7313134366546945 1.1767323932067022 0.2393023342822557 1.0 0.7875005338602749 3 O95394 1 +ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.513065680186479 1.171436118488271 0.2414235213294273 1.0 0.7875005338602749 21 Q9Y6V7,Q96GQ7,Q86XP3,Q9H0S4,Q8NHQ9,Q8TDD1,Q9BUQ8,Q9NVP1 8 +Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.5104163698391462 1.1248279386495543 0.2606619528940233 1.0 0.8209353458961193 15 Q5T160,Q9UGM6 2 +Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866] 0.6937220222060967 1.0316811188287298 0.3022215253369746 1.0 0.8449867136972556 3 Q9P2R7 1 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.6851628468033852 0.9988948757581354 0.3178456188085758 1.0 0.8657470376422652 3 Q99536,Q8N4Q0 2 +Ribosomal protein L7Ae conserved site [IPR004037] 0.9207114862827802 0.9117797265821576 0.3618846846758561 1.0 0.9485406143107624 2 P55769 1 +Ribosomal protein L24e, conserved site [IPR023442] 0.8839312631896271 0.7928389453514675 0.4278716628315244 1.0 0.9974592010730864 2 Q9UHA3 1 +Calreticulin/calnexin, conserved site [IPR018124] 0.6145958986731004 0.7350221900230031 0.4623259800594232 1.0 0.9974592010730864 3 O14967,P27797 2 +WD40 repeat, conserved site [IPR019775] 0.2863975047894473 0.6690933643536383 0.503435922588847 1.0 1.0 49 P61962,O75083,Q12788,Q96DI7,Q13610,Q9BZK7,Q8TAF3,Q86W42 8 +Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314] 0.8326801326499792 0.6343682466818975 0.5258405272086433 1.0 1.0 2 Q8TEA1 1 +DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.4151170705002129 0.6267349768181766 0.5308329724814596 1.0 1.0 17 Q8IX18,P54132,Q9H2U1,Q92620,Q14839,Q9UNY4,Q7Z478,Q9H6R0 8 +Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.822731383780519 0.604851658625617 0.5452775657389792 1.0 1.0 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.822731383780519 0.604851658625617 0.5452775657389792 1.0 1.0 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.822731383780519 0.604851658625617 0.5452775657389792 1.0 1.0 2 Q07820 1 +Inositol monophosphatase, conserved site [IPR020550] 0.570897229414133 0.5811208955171628 0.561158976635475 1.0 1.0 3 Q9NX62 1 +Macrophage migration inhibitory factor, conserved site [IPR019829] 0.7732891166716769 0.4657894680431617 0.6413662044789676 1.0 1.0 2 P14174 1 +DNA topoisomerase, type IIA, conserved site [IPR018522] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 1.0 2 Q02880 1 +DnaJ domain, conserved site [IPR018253] 0.3540177513547977 0.4020254431150487 0.687665301514752 1.0 1.0 10 Q8WXX5,P25685,P31689,O60884 4 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.4239038139609042 0.388548024605506 0.6976105216020476 1.0 1.0 5 Q9UBF8 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.408889737093297 0.3397749416416088 0.7340260200822177 1.0 1.0 5 O15400,Q86Y82 2 +Ribosomal protein L3, conserved site [IPR019926] 0.7199276454627594 0.3332224442939593 0.73896637723738 1.0 1.0 2 P39023 1 +AT hook, DNA-binding motif [IPR017956] 0.713898100693386 0.3195887294779603 0.7492801192255587 1.0 1.0 2 P17096 1 +Ribosomal protein L30, conserved site [IPR018038] 0.7048537835393303 0.299694732934985 0.7644100165591479 1.0 1.0 2 Q6DKI1 1 +Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131] 0.6819415134157306 0.2523988901377588 0.8007327579247185 1.0 1.0 2 Q9NQW7 1 +CAP, conserved site, N-terminal [IPR018106] 0.6795296955079795 0.247686832025627 0.8043767209876216 1.0 1.0 2 P40123 1 +CAP, conserved site, C-terminal [IPR028417] 0.6795296955079795 0.247686832025627 0.8043767209876216 1.0 1.0 2 P40123 1 +Dynein light chain, type 1/2, conserved site [IPR019763] 0.6777208320771738 0.2441867662052574 0.8070861759326093 1.0 1.0 2 Q96FJ2 1 +Chaperonin TCP-1, conserved site [IPR002194] 0.3349441256417947 0.2430249653604612 0.8079860575498132 1.0 1.0 8 Q99832,P48643,P40227,P78371,P49368,P50990,P17987 7 +F-actin capping protein, alpha subunit, conserved site [IPR017865] 0.655712993668977 0.2039710621340179 0.8383761125799212 1.0 1.0 2 P52907 1 +ABC transporter-like, conserved site [IPR017871] 0.3032285486927907 0.1967873445471972 0.8439939550591373 1.0 1.0 9 O15439 1 +Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628] 0.6403376545070764 0.1785169314071246 0.858317025420398 1.0 1.0 2 Q6UB35 1 +GTP1/OBG, conserved site [IPR006074] 0.6276756104914045 0.1592067276462049 0.8735060035744231 1.0 1.0 2 P55039 1 +Phosphofructokinase, conserved site [IPR015912] 0.3869119420989164 0.1152969081675203 0.9082097889458172 1.0 1.0 3 P08237,P17858 2 +Tr-type G domain, conserved site [IPR031157] 0.2997525477685417 0.0886072334815028 0.929394059213732 1.0 1.0 5 Q96RP9 1 +Aldo/keto reductase, conserved site [IPR018170] 0.5679831172746388 0.0879629806614739 0.9299060992034364 1.0 1.0 2 P15121 1 +IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.4947241483267888 0.0399602771288158 0.9681247952398452 1.0 1.0 2 P12268 1 +Ubiquitin conserved site [IPR019954] 0.4892975580343536 0.0377866936290451 0.9698577537419872 1.0 1.0 2 P46379 1 +ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.4579439252336297 0.0280381678116301 0.9776317095919912 1.0 1.0 2 P53396 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867] 0.3693096171239059 0.0173144705734067 0.9861857414859304 1.0 1.0 2 P11586 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e15dfa31c7bf9a01b862f9ed8238d307cec12e68 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FHF complex subunit HOOK interacting protein, KELAA motif [IPR045668]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAP2", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CDX2", "CECR2", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DIS3L2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FAM160A2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD13", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NFKB1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NSUN6", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RECQL5", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX4", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE1", "SYNE2", "TAP1", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCC4", "ACLY", "AKR1B1", "BAG6", "BLM", "CALR", "CAP2", "CAPZA1", "CCT2", "CCT3", "CCT5", "CCT6A", "CCT7", "CCT8", "CHD4", "CLGN", "DCAF7", "DDX18", "DDX23", "DDX27", "DDX42", "DDX47", "DDX49", "DDX54", "DDX55", "DHX29", "DHX33", "DHX36", "DHX38", "DHX40", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC9", "DRG2", "DYNLL2", "EPB41L2", "EPB41L5", "GFM1", "HMGA1", "IMPAD1", "IMPDH2", "MCL1", "MIF", "MTHFD1", "MTHFD1L", "NSUN6", "PFKL", "PFKM", "PGM3", "PI4KB", "PPIC", "PPIE", "PPIF", "PPIL1", "PPIL3", "PWP1", "RARS2", "RPL3", "RPL7L1", "RSL24D1", "SNRNP40", "SNU13", "STX12", "STX7", "SUCLA2", "TBL1XR1", "TBL3", "TCP1", "THOC6", "TOP2B", "TTF2", "VAT1", "WARS2", "WDR1", "WDR48", "XPNPEP1", "ZADH2"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 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"Domain of unknown function DUF1605 [IPR011709]", "16": "Helicase-associated domain [IPR007502]", "17": "SANT domain [IPR017884]", "18": "Myb domain [IPR017930]", "19": "RNA recognition motif domain [IPR000504]", "20": "Thioredoxin domain [IPR013766]", "21": "Double-stranded RNA-binding domain [IPR014720]", "22": "SAP domain [IPR003034]", "23": "Cullin, N-terminal [IPR001373]", "24": "DnaJ domain [IPR001623]", "25": "Proteasome alpha-subunit, N-terminal domain [IPR000426]"} \ No newline at end of file diff --git a/interpro_domain/basic/plot_0.png b/interpro_domain/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..abc6a1ca8f8a9f5e8301c2b2676717234b0965d0 --- /dev/null +++ b/interpro_domain/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4dbe5aec3f56b2119152fb79e08ea0b2e1b84c1442350df01d0b3a2f30145ff +size 146697 diff --git a/interpro_domain/basic/plot_1.png b/interpro_domain/basic/plot_1.png new file mode 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b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..947546d076089b80ccbe8564a6235da19b096d6f --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a2567b123cf6b2386c2b4c9e6e3a54807c885b57bc2d2dabe1145ad94ec270d8 +size 187793 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b13c74b62ffdeb7c07471d6c46ba1b917a4d8aba --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,18 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Small GTP-binding protein domain [IPR005225] 18 52 3.0619708022571657 0.002198848997772 15.402912621359222 47.23300970873787 -0.371316870036326 0.6367413862110247 7.225748945771396 5.046779004503178 0.8013178256262974 0.3189581513631314 0.1185798153291669 0.1157235318918368 0.0097342185306864 8.086738930057514e-05 +DEAD/DEAH box helicase domain [IPR011545] 24 49 2.518026966667906 0.0118014285222303 21.74514563106796 45.657766990291265 -0.941097113011442 0.4397780266593282 7.945848322320019 2.5085993585710296 1.0909466861878467 0.3627389323469597 0.2597451867723493 0.1202677732034906 0.003679644907473 3.2726045596092214e-05 +Matrin/U1-C-like, C2H2-type zinc finger [IPR003604] 5 9 2.503711317174264 0.0122898265019875 3.3932038834951457 7.70873786407767 -0.5740714135189678 0.484087264420793 2.0146917727071916 1.449010830737796 0.9099300059415022 0.3204484897971323 0.0065792573185243 0.0246740936940832 0.1243944683174773 0.0010754462643065 +Linker histone H1/H5, domain H15 [IPR005818] 5 6 2.4126871589144465 0.0158354049877038 4.621359223300971 6.101941747572815 -1.4616951902178734 0.1781780847215095 1.4983259581225516 0.4870120076915772 1.3151991134793464 0.2676299008151665 1.0 0.0938999510605359 0.00153832558414 2.395450982999456e-06 +Biotin carboxylase, C-terminal [IPR005482] 2 5 2.256769981688141 0.024022451379055 4.461165048543689 4.890776699029126 -1.9512728700118385 0.0878866289004478 0.922189565175296 0.311919174620445 1.421470494110228 0.2050995660155357 1.0 0.0480955538847994 0.0001404453908609 0.0010884780632536 +Biotin carboxylase-like, N-terminal domain [IPR005481] 2 5 2.256769981688141 0.024022451379055 4.461165048543689 4.890776699029126 -1.9512728700118385 0.0878866289004478 0.922189565175296 0.311919174620445 1.421470494110228 0.2050995660155357 1.0 0.0480955538847994 0.0001404453908609 0.0010884780632536 +Biotin carboxylation domain [IPR011764] 2 5 2.256769981688141 0.024022451379055 4.461165048543689 4.890776699029126 -1.9512728700118385 0.0878866289004478 0.922189565175296 0.311919174620445 1.421470494110228 0.2050995660155357 1.0 0.0480955538847994 0.0001404453908609 0.0010884780632536 +Immunoglobulin subtype 2 [IPR003598] 6 9 2.196359818767592 0.0280661992697091 2.8106796116504853 8.04126213592233 0.1764352420775828 0.5005828106358552 2.0581551085254395 2.677802743524345 1.0491539805619012 0.3137632145774063 0.0437266531990119 0.0289872856979344 0.0253794402510323 0.0481713311969391 +Immunoglobulin subtype [IPR003599] 6 9 2.196359818767592 0.0280661992697091 2.9684466019417477 8.483009708737864 0.1381371967634491 0.4928258967784709 2.271921156707309 2.9216637549507847 1.0756254869730633 0.312999744433737 0.0817843887077026 0.0697861672764856 0.0897131183396691 0.197919794715469 +Spen paralogue and orthologue SPOC, C-terminal [IPR012921] 0 5 2.15317983469688 0.0313045478530091 2.4975728155339807 4.019417475728155 -0.7055408639367386 0.4178307209416068 1.2856542031723737 0.900168080575418 0.9845607067982224 0.3130383131537134 0.0242848323540905 0.0480955538847994 0.1167524715539159 0.2223361188783073 +Myosin, N-terminal, SH3-like [IPR004009] 0 5 2.072405244279267 0.0382276647088015 2.412621359223301 4.684466019417476 -0.1448549248535419 0.5229359227697599 1.417517288923896 0.97664546553505 0.9807639625700678 0.3174032539640412 0.0479914252810258 0.0938999510605359 0.2199219252501269 0.3953154189841972 +Biotin/lipoyl attachment [IPR000089] 4 8 2.0659134840744726 0.0388366494202898 5.182038834951456 8.361650485436893 -2.130161056715037 0.0953326994482326 1.4807396860722422 0.6846338360686358 1.3497960821287889 0.2162773212056401 1.0 0.0938999510605359 0.00153832558414 0.0009470318558772 +Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 1 5 2.0470160481216766 0.0406565088743895 2.9611650485436893 5.067961165048544 -0.667320777745365 0.4263445669465814 1.3998774571686892 0.5789534569272068 0.9506639271252796 0.308773856990838 0.0385773062479974 0.0758460972151271 0.1801790130745941 0.0552139444550738 +Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479] 2 6 2.0183959154539 0.0435500444468859 4.555825242718447 5.890776699029126 -2.014668773126755 0.0893555876700455 0.9291869546245032 0.311919174620445 1.4520862177793892 0.2126509357606074 1.0 0.0666860823201616 0.0004739047104592 0.0035377925598295 +Helicase, C-terminal [IPR001650] 33 67 2.017662256236919 0.043626448264169 28.276699029126213 64.14320388349515 -0.9672766379128034 0.4261152822982564 10.427332491581874 5.572677576013035 1.2520825297778568 0.3669747508835076 0.3928429005031874 0.2607188184236454 0.0033146563909175 0.0003904737712984 +Helicase superfamily 1/2, ATP-binding domain [IPR014001] 32 66 1.996694945645198 0.045858331532772 27.6504854368932 63.62864077669903 -0.9443151127920844 0.4282724259781093 10.313492659245568 5.911191877671367 1.2363240700501756 0.3661096810292873 0.3988427362229673 0.2680066972469274 0.0037402636580435 0.0004788538684469 +Exoribonuclease, phosphorolytic domain 1 [IPR001247] 3 6 1.9732013320516315 0.0484726287840486 3.4757281553398056 5.970873786407767 -0.7224223652638475 0.4516190241506664 1.6813925123151383 0.90528449296138 0.8042796304231143 0.311821944199576 1.0 1.0 1.0 0.0427743402023459 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bbfaae8328f762d5f7dd7acd45c0baef8decf53c --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 2688, + "title": "Average number of proteins per term", + "value": 2.1923363095238093 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8fa8eec9ed7fc3efb0e9f0124d9b1035291cade5 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1140464bf6056756034845bd944c2dba3821d4c2 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,259 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Small GTP-binding protein domain [IPR005225] 0.5246968160238424 3.0619708022571657 0.002198848997772 0.9973067693008728 0.4536092798760093 52 Q9NVJ2,Q92930,Q9NP72,Q15286,P51148,Q96RP9,P62330,Q969Y2,O75616,P20339,P61019,P60953,P51153,Q9BZE4,Q9BZG1,P62820,Q15382,P20338 18 +DEAD/DEAH box helicase domain [IPR011545] 0.4640790605416257 2.518026966667906 0.0118014285222303 0.999999999999986 0.4536092798760093 49 Q9H2U1,Q9NY93,Q8N3C0,Q9NVP1,O75643,Q8NHQ9,Q8TDD1,Q7L2E3,Q7Z478,Q9H6R0,Q9BQ39,Q7L014,Q9Y6V7,Q9NR30,Q92620,Q13206,Q9H0S4,O00148,P54132,Q96GQ7,Q86XP3,Q9BUQ8,Q8IX18,Q9NUL7 24 +Matrin/U1-C-like, C2H2-type zinc finger [IPR003604] 0.810466728461607 2.503711317174264 0.0122898265019875 0.9999999999999964 0.4536092798760093 9 P09234,Q15428,Q5VUA4,Q9ULV3,Q969S3 5 +Linker histone H1/H5, domain H15 [IPR005818] 0.8837911258677938 2.4126871589144465 0.0158354049877038 1.0 0.4536092798760093 6 P10412,P16403,Q5SSJ5,Q92522,P07305 5 +Biotin carboxylase, C-terminal [IPR005482] 0.8737717712018609 2.256769981688141 0.024022451379055 1.0 0.4536092798760093 5 Q96RQ3,P05165 2 +Biotin carboxylase-like, N-terminal domain [IPR005481] 0.8737717712018609 2.256769981688141 0.024022451379055 1.0 0.4536092798760093 5 Q96RQ3,P05165 2 +Biotin carboxylation domain [IPR011764] 0.8737717712018609 2.256769981688141 0.024022451379055 1.0 0.4536092798760093 5 Q96RQ3,P05165 2 +Immunoglobulin subtype 2 [IPR003598] 0.7447459152887135 2.1963598187675917 0.0280661992697091 1.0 0.4536092798760093 9 P10586,P35613,Q13740,Q9Y624,Q9BY67,O75962 6 +Immunoglobulin subtype [IPR003599] 0.7447459152887135 2.1963598187675917 0.0280661992697091 1.0 0.4536092798760093 9 P10586,P35613,Q13740,Q9Y624,Q9BY67,O75962 6 +Macro domain [IPR002589] 0.904899159004624 2.1361424264591116 0.032667806517642 1.0 0.4536092798760093 4 Q9P0M6,Q9NXN4 2 +Biotin/lipoyl attachment [IPR000089] 0.7464514888710236 2.0659134840744726 0.0388366494202898 1.0 0.4536092798760093 8 Q96RQ3,P11498,P05165,P10515 4 +Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 0.8226400351754474 2.0470160481216766 0.0406565088743895 1.0 0.4536092798760093 5 P55769 1 +Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479] 0.7889206727183962 2.0183959154539 0.0435500444468859 1.0 0.4536092798760093 6 Q96RQ3,P05165 2 +Helicase, C-terminal [IPR001650] 0.4536459613694307 2.017662256236919 0.043626448264169 1.0 0.4536092798760093 67 Q9H2U1,Q9NY93,Q8N3C0,Q9UNY4,Q9NVP1,O75643,Q8IYB8,P28370,Q8NHQ9,Q8TDD1,Q7L2E3,Q6ZRS2,Q7Z478,Q9H6R0,Q9BQ39,Q7L014,Q9Y6V7,Q9NR30,Q92620,Q2NKX8,Q14839,Q13206,Q9H0S4,O00148,P46100,P54132,Q96GQ7,O60264,Q86XP3,Q9BUQ8,Q14527,Q8IX18,Q9NUL7 33 +Helicase superfamily 1/2, ATP-binding domain [IPR014001] 0.4496026226577264 1.996694945645198 0.045858331532772 1.0 0.4536092798760093 66 Q9H2U1,Q9NY93,Q8N3C0,Q9UNY4,Q9NVP1,O75643,P28370,Q8NHQ9,Q8TDD1,Q7L2E3,Q6ZRS2,Q7Z478,Q9H6R0,Q9BQ39,Q7L014,Q9Y6V7,Q9NR30,Q92620,Q2NKX8,Q14839,Q13206,Q9H0S4,O00148,P46100,P54132,Q96GQ7,O60264,Q86XP3,Q9BUQ8,Q14527,Q8IX18,Q9NUL7 32 +Exoribonuclease, phosphorolytic domain 1 [IPR001247] 0.7782980312909 1.9732013320516313 0.0484726287840486 1.0 0.4536092798760093 6 Q5RKV6,Q06265,Q8TCS8 3 +Matrin/U1-C, C2H2-type zinc finger [IPR000690] 0.7728564863359041 1.9499717821460083 0.0511794824052391 1.0 0.4536092798760093 6 Q15428,Q9ULV3 2 +RAP domain [IPR013584] 0.9282267792521168 1.9349301707508813 0.0529988652453381 1.0 0.4536092798760093 3 Q9NYY8,Q7L8L6 2 +FAST kinase-like protein, subdomain 2 [IPR013579] 0.9282267792521168 1.9349301707508813 0.0529988652453381 1.0 0.4536092798760093 3 Q9NYY8,Q7L8L6 2 +FAST kinase leucine-rich [IPR010622] 0.9282267792521168 1.9349301707508813 0.0529988652453381 1.0 0.4536092798760093 3 Q9NYY8,Q7L8L6 2 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130] 0.6582236954118619 1.9173083521619012 0.0551987694841622 1.0 0.4536092798760093 12 Q9Y3C6,Q96BP3,Q9UNP9,P30405,Q9H2H8,P45877 6 +Immunoglobulin I-set [IPR013098] 0.8457036983703364 1.9032691356109337 0.0570054360245007 1.0 0.4536092798760093 4 O75962,P10586 2 +Immunoglobulin-like domain [IPR007110] 0.6441907311894622 1.84543350293164 0.0649745033177726 1.0 0.4548215232244086 13 P10586,P35613,P10321,Q13740,Q9Y624,Q13308,Q9BY67,O75962 8 +ATP-grasp fold [IPR011761] 0.6951881018386206 1.8277553581743244 0.0675862758284553 1.0 0.4597461610875293 8 Q96RQ3,P05165 2 +Zinc finger, double-stranded RNA binding [IPR022755] 0.7680568917232021 1.818207842218048 0.0690323718484151 1.0 0.4626499711781479 5 Q9ULV3 1 +Forkhead-associated (FHA) domain [IPR000253] 0.6382790531437372 1.8161959256801108 0.0693403228671827 1.0 0.4626499711781479 10 Q5SW79,O60333,O60934,Q12972,P46013,Q14676 6 +Immunoglobulin V-set domain [IPR013106] 0.8968636911942233 1.8161528012009005 0.0693469359821086 1.0 0.4626499711781479 3 Q13740,Q9Y624 2 +Phospholipid/glycerol acyltransferase [IPR002123] 0.8226114595120738 1.8110793105958132 0.0701285756451497 1.0 0.4631587502067875 4 Q92604 1 +FERM domain [IPR000299] 0.7122660638577294 1.7907053504780777 0.0733405906633009 1.0 0.4675836859157076 7 Q9HCM4,O43491 2 +Exoribonuclease, phosphorolytic domain 2 [IPR015847] 0.7591970092847105 1.7806263758477912 0.0749735079440261 1.0 0.4675836859157076 5 Q06265,Q8TCS8 2 +TRASH domain [IPR011017] 0.8140181782933318 1.776595001773458 0.075634898604362 1.0 0.4675836859157076 4 Q9UHA3,Q9UBW7 2 +FERM central domain [IPR019748] 0.6822245552147654 1.7667563266031656 0.0772690456917957 1.0 0.4675836859157076 8 Q9HCM4,O43491 2 +Band 4.1 domain [IPR019749] 0.6822245552147654 1.7667563266031656 0.0772690456917957 1.0 0.4675836859157076 8 Q9HCM4,O43491 2 +FERM, N-terminal [IPR018979] 0.7251040328025645 1.7439534645840813 0.0811672046809963 1.0 0.4712255857073827 6 Q9HCM4,O43491 2 +FERM, C-terminal PH-like domain [IPR018980] 0.7251040328025645 1.7439534645840813 0.0811672046809963 1.0 0.4712255857073827 6 Q9HCM4,O43491 2 +Brix domain [IPR007109] 0.7954751131221727 1.7018750837535976 0.088778787472791 1.0 0.4780112702597276 4 Q9H7B2,Q9H9Y2,Q8TDN6 3 +CRAL-TRIO lipid binding domain [IPR001251] 0.737551253661398 1.6883398763546127 0.0913460046687917 1.0 0.4780112702597276 5 O75962,Q07960 2 +GTP binding domain [IPR006073] 0.6089467916602963 1.6600716255491093 0.0969000442822909 1.0 0.4915733981394783 11 O75616,Q13823,Q969Y2 3 +Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152] 0.6865707038044276 1.5751606764752644 0.1152193614098218 1.0 0.5321471537278368 6 Q10567,O95782,Q9UJY5 3 +ENTH domain [IPR013809] 0.7266628937728743 1.4215854362284934 0.1551466351312451 1.0 0.597415910127089 4 Q9Y6I3 1 +RNA helicase, DEAD-box type, Q motif [IPR014014] 0.5433127315357855 1.4193420689247798 0.155799312871685 1.0 0.597415910127089 25 Q7L014,Q9Y6V7,Q96GQ7,Q86XP3,Q8NHQ9,Q9NY93,Q13206,Q8TDD1,Q9H0S4,Q9BUQ8,Q9NUL7 11 +2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078] 0.7895691699576444 1.4029613434105748 0.1606283665948837 1.0 0.6058477433639239 3 P10515 1 +Histone H2A, C-terminal domain [IPR032454] 0.7842936760685013 1.3824721205179205 0.166826785045639 1.0 0.6069248225776953 3 Q9P0M6 1 +Histone H2A/H2B/H3 [IPR007125] 0.7842936760685013 1.3824721205179205 0.166826785045639 1.0 0.6069248225776953 3 Q9P0M6 1 +Domain of unknown function DUF4217 [IPR025313] 0.7840772014475548 1.3816312339428325 0.1670849585965381 1.0 0.6069248225776953 3 Q9NVP1,Q8NHQ9 2 +LSM domain, eukaryotic/archaea-type [IPR001163] 0.6396535714799612 1.3673530738044637 0.1715146634924806 1.0 0.6163521597162942 6 P62304,P62318,P62312,P62314 4 +Myosin head, motor domain [IPR001609] 0.5943588122612887 1.347288008964996 0.1778874925060622 1.0 0.6250478168056149 8 O00159,Q92614 2 +FERM adjacent (FA) [IPR014847] 0.7734546651685963 1.3403595139627875 0.1801284914565366 1.0 0.6261082494762819 3 Q9HCM4 1 +Zinc finger, CCHC-type [IPR001878] 0.5657448245190254 1.315301118582492 0.1884087223554393 1.0 0.6362344795118354 9 Q7Z6E9,Q9NUD5,Q8TBF4 3 +RNA recognition motif domain, eukaryote [IPR003954] 0.5430256268661017 1.3022213884880136 0.1928407156221139 1.0 0.6396112306556816 14 Q8TBF4,Q9Y4C8,P31483 3 +S1 domain [IPR003029] 0.5867789868587865 1.215120745342734 0.2243200423602998 1.0 0.6820953324258889 7 P62487,Q8TCS8 2 +DZF domain [IPR006561] 0.6739049809883615 1.2050186826034897 0.2281960896699293 1.0 0.6876581715614014 4 Q96KR1,Q12905 2 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844] 0.7313134366546943 1.1767323932067018 0.239302334282256 1.0 0.7060863606484129 3 O95394 1 +ATP-citrate lyase/succinyl-CoA ligase [IPR005811] 0.6660212196453414 1.1726823025962123 0.2409232309330189 1.0 0.7069886951396888 4 Q9P2R7 1 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.665468504214758 1.170416430813616 0.2418334266268686 1.0 0.7081135629335763 4 Q8TEA1 1 +SANT/Myb domain [IPR001005] 0.5157233272617183 1.1668407598137074 0.2432746831175405 1.0 0.7104288453417407 11 Q92922,P28370,Q13330,O60264,Q99459,Q8TAQ2,Q15554,O94776 8 +Arf GTPase activating protein [IPR001164] 0.6166393649026574 1.164782253892872 0.2441071439673536 1.0 0.7104288453417407 5 Q8WU79 1 +SUN domain [IPR012919] 0.7278320978992558 1.1632459785198943 0.2447297166792745 1.0 0.7104288453417407 3 O94901 1 +KOW [IPR005824] 0.6161738080868996 1.16275963012027 0.2449270404978012 1.0 0.7104288453417407 5 P61254,Q92917,P61353,P62701 4 +Chromatin target of PRMT1 protein, C-terminal [IPR025715] 0.9942719324690984 1.157892121387324 0.246908063091201 1.0 0.7144121351874579 2 Q86V81 1 +v-SNARE, coiled-coil homology domain [IPR042855] 0.693960726240507 1.032597076284185 0.3017924969834518 1.0 0.7815204546161063 3 O75396 1 +Longin domain [IPR010908] 0.693960726240507 1.032597076284185 0.3017924969834518 1.0 0.7815204546161063 3 O75396 1 +NUC153 [IPR012580] 0.9553813687066623 1.026712314067017 0.3045559491235263 1.0 0.782496382593059 2 Q9BSC4 1 +RNA-binding domain, S1 [IPR022967] 0.5264384576533792 1.0215842747965211 0.3069777034699319 1.0 0.7843688849117653 8 P62487,Q8TCS8 2 +RNA polymerase Rpb1, domain 3 [IPR007066] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.7857723060395461 3 P24928 1 +RNA polymerase Rpb1, domain 4 [IPR007083] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.7857723060395461 3 P24928 1 +RNA polymerase, N-terminal [IPR006592] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.7857723060395461 3 P24928 1 +RNA polymerase, alpha subunit [IPR000722] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.7857723060395461 3 P24928 1 +RNA polymerase Rpb1, domain 1 [IPR007080] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.7857723060395461 3 P24928 1 +RNA polymerase Rpb1, domain 5 [IPR007081] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.7857723060395461 3 P24928 1 +Transketolase-like, pyrimidine-binding domain [IPR005475] 0.6833534378769514 0.991978966060044 0.3212077861503921 1.0 0.7895114553995883 3 Q02218,P11177 2 +RecF/RecN/SMC, N-terminal [IPR003395] 0.5738804128976573 0.9799296062518522 0.3271208675441723 1.0 0.7914499477576376 5 O95347,Q96SB8 2 +SCP2 sterol-binding domain [IPR003033] 0.6746079613992797 0.9586343617076982 0.3377429757495549 1.0 0.8041214515631565 3 Q6YN16,P22307 2 +Exonuclease, RNase T/DNA polymerase III [IPR013520] 0.6102350948668499 0.9455719271674068 0.3443669683646884 1.0 0.8123739236315585 4 Q9GZR2 1 +Tim10-like [IPR004217] 0.6649577804583776 0.9220157092279796 0.35652038161831 1.0 0.8197833924636589 3 O60220,Q9Y5J9 2 +SNF2, N-terminal [IPR000330] 0.4716795329034143 0.919994409548218 0.3575756806531931 1.0 0.8201053153547637 14 P46100,P28370,Q14839,Q2NKX8,O60264,Q9H4L7,Q9UNY4,Q6ZRS2,Q14527 9 +Syntaxin, N-terminal domain [IPR006011] 0.664053075995176 0.9185930590109924 0.3583084638403404 1.0 0.8210853800535679 3 O15400,Q86Y82 2 +Core histone macro-H2A, macro domain [IPR035796] 0.922520349713596 0.9177165734841513 0.3587672685731413 1.0 0.8214364718267495 2 Q9P0M6 1 +Disulphide isomerase [IPR005788] 0.5569233566519853 0.9074740311145992 0.3641561761624989 1.0 0.8218046256070053 5 Q8NBS9,P30101,P13667 3 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.6604342581423477 0.9049213956470608 0.3655070312540467 1.0 0.8218046256070053 3 P20020,P16615 2 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.6604342581423477 0.9049213956470608 0.3655070312540467 1.0 0.8218046256070053 3 P20020,P16615 2 +Zinc finger, CCCH-type [IPR000571] 0.4635431106904379 0.8746771322338486 0.381749606098491 1.0 0.8385696434627057 15 Q9NW64,Q9NXH9,O75152,Q96QC0,Q8WU90 5 +Glycosyl hydrolase, family 13, catalytic domain [IPR006047] 0.9089538739825131 0.8733750814293083 0.3824586685845825 1.0 0.8385696434627057 2 P08195 1 +Domain of unknown function DUF1605 [IPR011709] 0.4580686730986209 0.8539396186606399 0.3931384462345484 1.0 0.8441850883569425 13 Q8IX18,Q9H2U1,Q92620,Q7L2E3,Q7Z478,Q9H6R0 6 +Helicase-associated domain [IPR007502] 0.4580686730986209 0.8539396186606399 0.3931384462345484 1.0 0.8441850883569425 13 Q8IX18,Q9H2U1,Q92620,Q7L2E3,Q7Z478,Q9H6R0 6 +CD80-like, immunoglobulin C2-set [IPR013162] 0.896593307205299 0.8333743639509968 0.4046336282860401 1.0 0.8549023410145058 2 Q13740 1 +Bromo adjacent homology (BAH) domain [IPR001025] 0.5798727013829864 0.8244418930341644 0.4096885194372923 1.0 0.8585005764477806 4 O94776,Q13330 2 +Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866] 0.579524903084475 0.8230700017296694 0.4104681867236599 1.0 0.8585005764477806 4 P30048,Q13162 2 +Peroxiredoxin, C-terminal [IPR019479] 0.579524903084475 0.8230700017296694 0.4104681867236599 1.0 0.8585005764477806 4 P30048,Q13162 2 +Major sperm protein (MSP) domain [IPR000535] 0.638419782870935 0.8224871463911514 0.4107996991766411 1.0 0.8585005764477806 3 Q8NHP6,Q9P0L0 2 +SANT domain [IPR017884] 0.465182505964911 0.8177615490686233 0.4134933577668778 1.0 0.8611070621283474 9 Q92922,P28370,Q13330,O60264,Q8TAQ2,O94776 6 +Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364] 0.5771760622665508 0.8138157385824869 0.415750517469835 1.0 0.863630132116628 4 O43776,Q15046 2 +CCAAT-binding factor [IPR005612] 0.6355755499628455 0.8119404847770678 0.4168257825297803 1.0 0.8643037074421925 3 Q8WTT2 1 +Myb domain [IPR017930] 0.4809964832359494 0.808909490962995 0.4185672092696535 1.0 0.865468198859099 8 Q92922,Q13330,Q15554,Q8TAQ2,Q99459 5 +Rpn11/EIF3F, C-terminal [IPR024969] 0.5724051592152404 0.7950782533195321 0.4265679837674541 1.0 0.8686221351865344 4 O00487,O00303 2 +Dehydrogenase, E1 component [IPR001017] 0.8724751281278245 0.7565888583837993 0.4492962184119089 1.0 0.8877773181122133 2 P08559 1 +Proteasomal ATPase OB C-terminal domain [IPR032501] 0.516514640372704 0.7383942135988351 0.4602749298173454 1.0 0.8958863224830012 5 P62191,P17980 2 +SMCs flexible hinge [IPR010935] 0.5158092386757248 0.7355018818875333 0.4620338942984641 1.0 0.896299694668161 5 O95347,A6NHR9 2 +Transcription elongation factor S-II, central domain [IPR003618] 0.6073427941334795 0.7088318739721692 0.4784288154649236 1.0 0.909488441279855 3 Q92576 1 +Ribosomal protein S10 domain [IPR027486] 0.8534820621043127 0.6974850389865661 0.4854992990479367 1.0 0.9143684923228752 2 P60866 1 +CRIB domain [IPR000095] 0.503275338931602 0.684535226922534 0.4936372528283756 1.0 0.9179445789452207 5 Q9Y5S2 1 +Histidine kinase/HSP90-like ATPase [IPR003594] 0.4674366682677195 0.6776711863380661 0.4979801995277406 1.0 0.9212462328496674 7 Q02880,Q15120 2 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.5336349924585234 0.6463962980385538 0.5180227372641091 1.0 0.9408412957877872 4 P26599,Q9UKA9,P14866 3 +RNA-binding S4 domain [IPR002942] 0.5885100312614473 0.6419604395753028 0.5208988695775743 1.0 0.943514933574474 3 P62701 1 +Aminotransferase, class I/classII [IPR004839] 0.4696714935190117 0.6271239521316484 0.5305779876020651 1.0 0.9475869451672232 6 Q8TD30,P00505 2 +RNA recognition motif domain [IPR000504] 0.3976932368982045 0.6150589817891201 0.5385157693360707 1.0 0.9542059248354372 120 Q9NW64,Q96T37,Q8IXT5,Q96I25,Q86V81,Q9UKA9,Q15233,Q9BY77,Q86U42,Q8WXA9,O75821,P09012,P31483,Q13247,A0AV96,Q15056,Q13242,Q12849,P08621,Q13595,Q9UN86,P52272,Q9Y6M1,Q5T8P6,Q01085,Q92879,Q15424,Q9BTD8,P42696,P33240,Q14151,Q13148,Q9Y4C8,Q9UNP9,Q9NWH9,Q9BYG3,Q9P2K5,Q9P2N5,Q8IY67,P08579,O43347,Q15427,Q8TBF4,Q9NW13 44 +GUCT [IPR012562] 0.8248417244498061 0.6110742015994934 0.5411504581102984 1.0 0.9569818627634752 2 Q9BQ39 1 +CRA domain [IPR013144] 0.5746946433293385 0.5940851599532281 0.5524551559716202 1.0 0.966655978419078 3 Q9H871 1 +CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.5746946433293385 0.5940851599532281 0.5524551559716202 1.0 0.966655978419078 3 Q9H871 1 +OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365] 0.4795076695686962 0.5904546082198278 0.5548859090360603 1.0 0.966655978419078 5 O43776,Q15046 2 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.5728033163321575 0.5876172206744491 0.5567892495820479 1.0 0.9680785917700808 3 O60884 1 +SUN coiled coil domain 2 [IPR040994] 0.8085619535724982 0.5636376231393179 0.5730007765216611 1.0 0.9746435153490266 2 O94901 1 +Replication factor C, C-terminal [IPR013748] 0.5606151990349887 0.5464756131195763 0.5847390466215088 1.0 0.9835104480874196 3 P35249,P40937 2 +Thioredoxin domain [IPR013766] 0.3903950793288295 0.5460130067955715 0.5850569964627172 1.0 0.9835104480874196 26 Q96JJ7,O14530,Q8NBS9,P30048,Q13162,Q9Y320,O43819,O43396,P30101,Q9H3N1,Q8NBF2,Q8IXB1,Q14554,O76003,P13667,P30041 16 +ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650] 0.8004220681338577 0.5404299120610901 0.5889005840170825 1.0 0.9858213864043814 2 Q9P2R7 1 +Nop domain [IPR002687] 0.5563910279526663 0.5324458111227797 0.5944172635612082 1.0 0.9896052836968116 3 O00567 1 +NOSIC [IPR012976] 0.5563910279526663 0.5324458111227797 0.5944172635612082 1.0 0.9896052836968116 3 O00567 1 +Thiamine pyrophosphate enzyme, central domain [IPR012000] 0.7934880916490821 0.520946036990713 0.6024043637354224 1.0 0.9923474198216852 2 A1L0T0 1 +Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766] 0.7934880916490821 0.520946036990713 0.6024043637354224 1.0 0.9923474198216852 2 A1L0T0 1 +Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001] 0.7934880916490821 0.520946036990713 0.6024043637354224 1.0 0.9923474198216852 2 A1L0T0 1 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.4232000118057349 0.4969644337367931 0.6192141323249127 1.0 0.9923474198216852 7 Q9UHY1,Q13308 2 +Peptidase M24 [IPR000994] 0.4177732284411745 0.4760797138174144 0.6340175887912951 1.0 0.9923474198216852 7 Q9Y5B9,Q9NQH7,Q9NQW7 3 +Diacylglycerol kinase, catalytic domain [IPR001206] 0.7702743442870075 0.4577728647630531 0.6471156327503429 1.0 0.9923474198216852 2 Q9NRA0 1 +Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.5307105720143259 0.4499869191402224 0.6527198726088841 1.0 0.9923474198216852 3 Q9UBF8 1 +Glycosyltransferase 2-like [IPR001173] 0.4404339555066734 0.4453614038247545 0.6560585997585235 1.0 0.9923474198216852 5 Q9Y673 1 +Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553] 0.3639179695655432 0.4408769899847822 0.6593020526065041 1.0 0.9923474198216852 10 Q10567,O95782 2 +R3H domain [IPR001374] 0.5272802599661627 0.4393720913292239 0.6603919453850116 1.0 0.9923474198216852 3 O15226 1 +Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.4743125189821527 0.4369120831572172 0.6621751085945959 1.0 0.9923474198216852 4 Q13823,Q9BVP2 2 +DNA topoisomerase 2, TOPRIM domain [IPR034157] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 0.9923474198216852 2 Q02880 1 +C-terminal associated domain of TOPRIM [IPR031660] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 0.9923474198216852 2 Q02880 1 +DNA topoisomerase, type IIA, domain A [IPR002205] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 0.9923474198216852 2 Q02880 1 +TOPRIM domain [IPR006171] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 0.9923474198216852 2 Q02880 1 +DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 0.9923474198216852 2 Q02880 1 +DTHCT [IPR012542] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 0.9923474198216852 2 Q02880 1 +SLIDE domain [IPR015195] 0.7579137775097999 0.4255268117656828 0.6704526805360176 1.0 0.9923474198216852 2 O60264 1 +ISWI, HAND domain [IPR015194] 0.7579137775097999 0.4255268117656828 0.6704526805360176 1.0 0.9923474198216852 2 O60264 1 +Serine-threonine protein phosphatase, N-terminal [IPR031675] 0.7530901416942894 0.4132231859548308 0.6794431022328027 1.0 0.9923474198216852 2 P62140 1 +Alpha-D-phosphohexomutase, C-terminal [IPR005843] 0.7518842327404183 0.4101725641067368 0.6816793653233617 1.0 0.9923474198216852 2 O95394 1 +Double-stranded RNA-binding domain [IPR014720] 0.3587204803875149 0.4039008946397904 0.6862855984431815 1.0 0.9923474198216852 12 Q08211,O15226,Q9UPY3,Q8WYQ5,Q96SI9,O95793,Q12906,Q9H9J2 8 +CARP motif [IPR006599] 0.4639685679905929 0.4034530349404605 0.6866149781161701 1.0 0.9923474198216852 4 O75695 1 +C-CAP/cofactor C-like domain [IPR017901] 0.4639685679905929 0.4034530349404605 0.6866149781161701 1.0 0.9923474198216852 4 O75695 1 +THUMP domain [IPR004114] 0.7479650286403359 0.4003289355980098 0.688914258403891 1.0 0.9923474198216852 2 Q9NXG2 1 +Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846] 0.5141737032569369 0.399769708391378 0.6893261436364966 1.0 0.9923474198216852 3 Q15393,Q16531 2 +Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871] 0.5141737032569369 0.399769708391378 0.6893261436364966 1.0 0.9923474198216852 3 Q15393,Q16531 2 +BAT2, N-terminal [IPR009738] 0.5133764404800183 0.3974113921841519 0.6910641160113542 1.0 0.9923474198216852 3 Q9Y520 1 +Translation elongation factor EFG/EF2, domain IV [IPR005517] 0.5128257184848091 0.3957858432355182 0.6922630213180996 1.0 0.9923474198216852 3 Q96RP9 1 +SAP domain [IPR003034] 0.3566252335347635 0.3891821602183425 0.6971413993334885 1.0 0.9923474198216852 13 Q14151,Q9NWH9,P82979,Q9BUJ2,Q13435,Q15424 6 +Dbl homology (DH) domain [IPR000219] 0.4229815303432686 0.3854710963904575 0.6998884168472517 1.0 0.9923474198216852 5 O75962,Q9H8V3 2 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.4220383883599876 0.3823352020420438 0.7022127470112252 1.0 0.9923474198216852 5 Q99536,Q8N4Q0,P11766 3 +Ran binding domain [IPR000156] 0.4570887300068019 0.3818091087097023 0.7026029619476919 1.0 0.9923474198216852 4 P43487 1 +Phospholipase/carboxylesterase/thioesterase [IPR003140] 0.740126620440156 0.3809731233949044 0.7032231917620442 1.0 0.9923474198216852 2 Q5VWZ2 1 +Chaperone DnaJ, C-terminal [IPR002939] 0.4214258385026777 0.3803042949639119 0.7037195477015232 1.0 0.9923474198216852 5 P31689,O60884 2 +Nuclear transport factor 2, eukaryote [IPR018222] 0.5057054960197691 0.3750308744425983 0.7076375051499784 1.0 0.9923474198216852 3 Q9UN86 1 +Nuclear transport factor 2 domain [IPR002075] 0.5057054960197691 0.3750308744425983 0.7076375051499784 1.0 0.9923474198216852 3 Q9UN86 1 +Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036] 0.7283690081398876 0.352795490484485 0.7242417647517789 1.0 0.9923474198216852 2 P32322 1 +Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939] 0.7283690081398876 0.352795490484485 0.7242417647517789 1.0 0.9923474198216852 2 P32322 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.4967983560527889 0.3497730636256323 0.7265090157788934 1.0 0.9923474198216852 3 Q9BYT8 1 +Kinesin-associated [IPR032405] 0.7253542357551896 0.3457409151116701 0.7295374325159685 1.0 0.9923474198216852 2 O60333 1 +Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164] 0.7214350316551122 0.3366764217197025 0.7363608394746652 1.0 0.9923474198216852 2 O95782 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.4053947582085186 0.3288402594073392 0.7422764311912196 1.0 0.9923474198216852 5 O15439 1 +Ribosomal protein L11, N-terminal [IPR020784] 0.7069641242086224 0.3042761104582486 0.7609175439223064 1.0 0.9923474198216852 2 P30050 1 +Ribosomal protein L11, C-terminal [IPR020783] 0.7069641242086224 0.3042761104582486 0.7609175439223064 1.0 0.9923474198216852 2 P30050 1 +Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.7051552607778087 0.3003469388357949 0.7639125329094623 1.0 0.9923474198216852 2 Q13330 1 +ELM2 domain [IPR000949] 0.7051552607778087 0.3003469388357949 0.7639125329094623 1.0 0.9923474198216852 2 Q13330 1 +Ribosomal protein L30, N-terminal [IPR012988] 0.7048537835393303 0.299694732934985 0.7644100165591479 1.0 0.9923474198216852 2 Q6DKI1 1 +Ribosomal protein L7, eukaryotic/archaeal [IPR035808] 0.7048537835393303 0.299694732934985 0.7644100165591479 1.0 0.9923474198216852 2 Q6DKI1 1 +Ribosomal protein L30, ferredoxin-like fold domain [IPR016082] 0.7048537835393303 0.299694732934985 0.7644100165591479 1.0 0.9923474198216852 2 Q6DKI1 1 +Thioesterase domain [IPR006683] 0.7015375339161898 0.2925708175130578 0.7698502224134023 1.0 0.9923474198216852 2 Q9NPJ3 1 +Glutathione S-transferase, C-terminal [IPR004046] 0.317035189372282 0.2672331786175583 0.7892896319084497 1.0 0.9923474198216852 11 O43324 1 +PDZ domain [IPR001478] 0.3238276207203098 0.2669586678690961 0.7895009847443659 1.0 0.9923474198216852 26 Q92614 1 +Zinc finger, GATA-type [IPR000679] 0.4140267367259169 0.2589011895134683 0.7957114803722207 1.0 0.9923474198216852 4 Q13330 1 +Transketolase, C-terminal domain [IPR033248] 0.683147422369612 0.2547742646796959 0.7988974532955511 1.0 0.9923474198216852 2 P11177 1 +Calponin homology domain [IPR001715] 0.3144983003335077 0.2527197993120729 0.8004847467835889 1.0 0.9923474198216852 29 O15020 1 +Aminopeptidase P, N-terminal [IPR007865] 0.6819415134157318 0.2523988901377613 0.8007327579247165 1.0 0.9923474198216852 2 Q9NQH7 1 +Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897] 0.6816400361772653 0.2518070587571644 0.8011902009962037 1.0 0.9923474198216852 2 P61011 1 +Signal recognition particle SRP54, helical bundle [IPR013822] 0.6816400361772653 0.2518070587571644 0.8011902009962037 1.0 0.9923474198216852 2 P61011 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631] 0.4577682693213992 0.2492675282134981 0.8031538474225592 1.0 0.9923474198216852 3 Q6UB35 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630] 0.4577682693213992 0.2492675282134981 0.8031538474225592 1.0 0.9923474198216852 3 Q6UB35 1 +Adenylate cyclase-associated CAP, N-terminal [IPR013992] 0.6795296955079795 0.247686832025627 0.8043767209876216 1.0 0.9923474198216852 2 P40123 1 +Adenylate cyclase-associated CAP, C-terminal [IPR013912] 0.6795296955079795 0.247686832025627 0.8043767209876216 1.0 0.9923474198216852 2 P40123 1 +Class I myosin, motor domain [IPR036072] 0.4569008897607797 0.247235988680182 0.804725594697679 1.0 0.9923474198216852 3 O00159 1 +Class I myosin tail homology domain [IPR010926] 0.4569008897607797 0.247235988680182 0.804725594697679 1.0 0.9923474198216852 3 O00159 1 +GNAT domain [IPR000182] 0.3671077456413316 0.2206112751151672 0.8253951210875048 1.0 0.9923474198216852 5 Q9H0A0 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.4435318804383679 0.2171069350710938 0.8281250094599519 1.0 0.9923474198216852 3 Q9BUJ2 1 +Valyl tRNA synthetase, anticodon-binding domain [IPR033705] 0.6569189026228431 0.2060600447997466 0.8367440085974707 1.0 0.9923474198216852 2 Q5ST30 1 +Helicase/SANT-associated domain [IPR014012] 0.6560144709074469 0.2044920508247763 0.8379690032770108 1.0 0.9923474198216852 2 Q6ZRS2 1 +Ribosomal L28e/Mak16 [IPR029004] 0.6551100391920381 0.2029316002096464 0.8391884947318928 1.0 0.9923474198216852 2 Q9BXY0 1 +Pentacotripeptide-repeat region of PRORP [IPR033443] 0.6548085619535632 0.2024131274667039 0.8395937665712803 1.0 0.9923474198216852 2 O75127 1 +ABC transporter-like, ATP-binding domain [IPR003439] 0.3032285486927907 0.1967873445471972 0.8439939550591373 1.0 0.9923474198216852 9 O15439 1 +EF hand associated, type-1 [IPR013566] 0.6505878806150103 0.1952427217143234 0.8452029354649784 1.0 0.9923474198216852 2 Q8IXI2 1 +EF hand associated, type-2 [IPR013567] 0.6505878806150103 0.1952427217143234 0.8452029354649784 1.0 0.9923474198216852 2 Q8IXI2 1 +MIRO domain [IPR020860] 0.6505878806150103 0.1952427217143234 0.8452029354649784 1.0 0.9923474198216852 2 Q8IXI2 1 +Histone-binding protein RBBP4, N-terminal [IPR022052] 0.6487790171842023 0.1922201869241776 0.8475697338669117 1.0 0.9923474198216852 2 Q16576 1 +CTLH, C-terminal LisH motif [IPR006595] 0.3396484485690477 0.1895246960381542 0.8496816011953816 1.0 0.9923474198216852 6 Q9H871 1 +60S ribosomal protein L10P, insertion domain [IPR040637] 0.6457642447995171 0.1872501062969618 0.8514645403902192 1.0 0.9923474198216852 2 P05388 1 +Aminotransferase class V domain [IPR000192] 0.6445583358456399 0.1852857205735227 0.8530049374463877 1.0 0.9923474198216852 2 Q9Y617 1 +Pleckstrin homology domain [IPR001849] 0.2933618408510005 0.1825726754621791 0.8551333257694644 1.0 0.9923474198216852 26 P31749,O75962,O15020 3 +HECT domain [IPR000569] 0.3244124684535626 0.1825633366795031 0.8551406538895774 1.0 0.9923474198216852 7 Q05086 1 +Brdt, bromodomain, repeat I [IPR043508] 0.6418450406994246 0.1809153167512252 0.8564340462071607 1.0 0.9923474198216852 2 P25440 1 +Brdt, bromodomain, repeat II [IPR043509] 0.6418450406994246 0.1809153167512252 0.8564340462071607 1.0 0.9923474198216852 2 P25440 1 +NET domain [IPR027353] 0.6418450406994246 0.1809153167512252 0.8564340462071607 1.0 0.9923474198216852 2 P25440 1 +Translation elongation factor EFTu-like, domain 2 [IPR004161] 0.3063422440722485 0.1716413379657679 0.8637195067032724 1.0 0.9923474198216852 8 Q15029,Q96RP9,O60841,P49411 4 +G-patch domain [IPR000467] 0.2831068683233426 0.1711504652899967 0.8641054556653327 1.0 0.9923474198216852 13 Q96BK5 1 +SMARCC, C-terminal [IPR032451] 0.6328007235453678 0.1668426759561836 0.8674938387205027 1.0 0.9923474198216852 2 Q8TAQ2 1 +SMARCC, N-terminal [IPR032450] 0.6328007235453678 0.1668426759561836 0.8674938387205027 1.0 0.9923474198216852 2 Q8TAQ2 1 +SMARCC, SWIRM-associated domain [IPR032448] 0.6328007235453678 0.1668426759561836 0.8674938387205027 1.0 0.9923474198216852 2 Q8TAQ2 1 +Methyltransferase type 11 [IPR013216] 0.4174394785130456 0.1649181714833246 0.8690083894665139 1.0 0.9923474198216852 3 O43709 1 +Peptidase M41 [IPR000642] 0.62827856496834 0.1600923662170392 0.8728083144937433 1.0 0.9923474198216852 2 Q9Y4W6 1 +GTP binding protein, second domain [IPR031662] 0.6276756104914045 0.1592067276462049 0.8735060035744231 1.0 0.9923474198216852 2 P55039 1 +Cullin, N-terminal [IPR001373] 0.312801932367147 0.1567015601291222 0.8754800574672854 1.0 0.9923474198216852 7 Q13616,Q13618,Q93034,Q13617,Q86Y37,Q13620 6 +Immunoglobulin C1-set [IPR003597] 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 0.9923474198216852 3 P10321 1 +MHC class I-like antigen recognition-like [IPR011161] 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 0.9923474198216852 3 P10321 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 0.9923474198216852 3 P10321 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 0.9923474198216852 3 P10321 1 +La-type HTH domain [IPR006630] 0.3328304164152021 0.1436935607876169 0.8857424561759912 1.0 0.9923474198216852 5 P05455,Q4G0J3,Q92615,Q71RC2 4 +Spt5 C-terminal domain [IPR024945] 0.6156165209526648 0.1422041312185824 0.886918768713794 1.0 0.9923474198216852 2 Q9UQ35 1 +Domain of unknown function DUF1747 [IPR013719] 0.6135061802833832 0.139367343211162 0.889159876824035 1.0 0.9923474198216852 2 Q9Y5B9 1 +Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155] 0.3132475466776566 0.1317619919710124 0.8951725503874497 1.0 0.9923474198216852 6 P41252,Q15031,Q5ST30 3 +Aminoacyl-tRNA synthetase, class Ia [IPR002300] 0.3132475466776566 0.1317619919710124 0.8951725503874497 1.0 0.9923474198216852 6 P41252,Q15031,Q5ST30 3 +Zinc finger C2H2-type [IPR013087] 0.2671048842482643 0.1302214058584447 0.8963912593538432 1.0 0.9923474198216852 23 Q96KM6,Q969S3,Q9ULV3 3 +Thioredoxin-like fold [IPR012336] 0.6044618631293271 0.1276743015089226 0.8984067280497565 1.0 0.9923474198216852 2 Q8NBF2 1 +CARG-binding factor, N-terminal [IPR012956] 0.602954476936986 0.1257983415319129 0.8998915546109427 1.0 0.9923474198216852 2 Q14103 1 +Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798] 0.5951160687368018 0.1163760150552883 0.907354543431642 1.0 0.9923474198216852 2 Q9UKA9 1 +Phosphofructokinase domain [IPR000023] 0.3869119420989164 0.1152969081675203 0.9082097889458172 1.0 0.9923474198216852 3 P08237,P17858 2 +Small-subunit processome, Utp12 [IPR007148] 0.3863761878928328 0.1145363011736285 0.9088126715558638 1.0 0.9923474198216852 3 Q15061 1 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058] 0.384800965018096 0.1123217447477756 0.9105683010842812 1.0 0.9923474198216852 3 Q5JPH6,P07814 2 +mRNA splicing factor Cwf21 domain [IPR013170] 0.5905939101597804 0.1111918312617515 0.9114642291739838 1.0 0.9923474198216852 2 Q9UQ35 1 +Ribosomal protein L10e/L16 [IPR016180] 0.5884835694904902 0.1088349932859681 0.9133333680358922 1.0 0.9923474198216852 2 Q9NX20 1 +FAD dependent oxidoreductase [IPR006076] 0.3399681620618861 0.1079149025319314 0.914063195648176 1.0 0.9923474198216852 4 Q8NCN5,Q96CU9 2 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.242415265727657 0.1074691933060666 0.9144167639314222 1.0 0.9923474198216852 13 O15217,O43324 2 +Glucosamine/galactosamine-6-phosphate isomerase [IPR006148] 0.584262888151937 0.1042395802732156 0.9169792245295614 1.0 0.9923474198216852 2 O95336 1 +F-BAR domain [IPR031160] 0.5703949351823874 0.0902316554096108 0.9281031295405348 1.0 0.9923474198216852 2 Q9UKS6 1 +FCH domain [IPR001060] 0.5703949351823874 0.0902316554096108 0.9281031295405348 1.0 0.9923474198216852 2 Q9UKS6 1 +Mad3/Bub1 homology region 1 [IPR013212] 0.5649683448899514 0.0851954942444868 0.9321059726314508 1.0 0.9923474198216852 2 O43683 1 +DnaJ domain [IPR001623] 0.2139912543344636 0.0822712107174679 0.9344310473116432 1.0 0.9923474198216852 17 Q8WXX5,O60884,P31689,Q9NZJ4,P25685,Q8IXB1 6 +K Homology domain, type 1 [IPR004088] 0.1965773461690647 0.0798447689679716 0.936360717474792 1.0 0.9928747962809628 26 Q8N9N2,Q8TCS8,Q13868 3 +eRF1 domain 2 [IPR005141] 0.5369309617123795 0.0629423108591969 0.9498124424263616 1.0 0.9994750004186692 2 Q9BRX2 1 +eRF1 domain 3 [IPR005142] 0.5369309617123795 0.0629423108591969 0.9498124424263616 1.0 0.9994750004186692 2 Q9BRX2 1 +eRF1 domain 1/Pelota-like [IPR005140] 0.5369309617123795 0.0629423108591969 0.9498124424263616 1.0 0.9994750004186692 2 Q9BRX2 1 +Sec63 domain [IPR004179] 0.3403246665669296 0.0626793890215045 0.9500218102937872 1.0 0.9994750004186692 3 Q8N3C0 1 +Proteasome alpha-subunit, N-terminal domain [IPR000426] 0.2475845410627992 0.0593727635395072 0.952655206325401 1.0 1.0 7 P25788,P25787,P25789,P28066,P25786,O14818 6 +PWI domain [IPR002483] 0.2744102258881536 0.0586784995665973 0.9532081846846336 1.0 1.0 5 Q9P2N5,Q5T8P6 2 +Rhodanese-like domain [IPR001763] 0.298187149291273 0.0586410462652583 0.95323801672578 1.0 1.0 4 P25325 1 +Ribosomal protein S4/S9, N-terminal [IPR001912] 0.5263792583659812 0.0560977390435215 0.9552639450860348 1.0 1.0 2 P46781 1 +ZU5 domain [IPR000906] 0.5137172143503057 0.0488910689689974 0.9610061062823734 1.0 1.0 2 Q12955 1 +La protein, xRRM domain [IPR014886] 0.49623153451913 0.0405925085179117 0.9676207565725534 1.0 1.0 2 Q4G0J3 1 +IMP dehydrogenase/GMP reductase [IPR001093] 0.4947241483267888 0.0399602771288158 0.9681247952398452 1.0 1.0 2 P12268 1 +XPC-binding domain [IPR015360] 0.4895990352728242 0.0379033182118813 0.9697647674014198 1.0 1.0 2 P54725 1 +RAD23A/RAD23B, UBA1 domain [IPR041811] 0.4895990352728242 0.0379033182118813 0.9697647674014198 1.0 1.0 2 P54725 1 +Nucleotidyl transferase domain [IPR005835] 0.2946177906272764 0.0342011129519242 0.972716779054304 1.0 1.0 3 Q96IJ6 1 +Alanyl-tRNA synthetase, class IIc, core domain [IPR018165] 0.2876960193003706 0.0314616854411195 0.9749013475965076 1.0 1.0 3 Q9BTE6,Q5JTZ9 2 +NOPS [IPR012975] 0.2813630880579121 0.0292504082998458 0.9766648784032036 1.0 1.0 3 Q15233,P23246 2 +CoA-binding [IPR003781] 0.4579439252336297 0.0280381678116301 0.9776317095919912 1.0 1.0 2 P53396 1 +Polyketide synthase, enoylreductase domain [IPR020843] 0.212805657118396 0.0210127595170397 0.983235477300792 1.0 1.0 6 Q99536,Q8N4Q0 2 +G-protein, beta subunit [IPR001632] 0.4169430208019198 0.0208626275041159 0.9833552390619962 1.0 1.0 2 Q13112 1 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059] 0.3846849562857976 0.0180835434473894 0.985572206232738 1.0 1.0 2 P07814 1 +3'-5' exonuclease domain [IPR002562] 0.3738317757009319 0.0175122033917858 0.9860279974409658 1.0 1.0 2 Q01780 1 +OBG-type guanine nucleotide-binding (G) domain [IPR031167] 0.1901025950512915 0.0165995054275246 0.9867561191162671 1.0 1.0 5 Q9BZE4,Q9Y295,P55039,A4D1E9 4 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..230a1f91bbadb015f935aa2ed7e7e25cb876fe08 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "10TM putative phosphate transporter, cytosolic domain [IPR027815]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAM10/ADAM17 catalytic domain [IPR034025]", "ADAM17, membrane-proximal domain [IPR032029]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "APPL1, BAR domain [IPR037929]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATF7-interacting protein , protein binding domain [IPR031870]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adaptor protein ClpS, core [IPR003769]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SOCS box protein 6, SOCS box domain [IPR037327]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRAP2, RNA recognition motif [IPR034932]", "BRCA1, serine-rich domain [IPR025994]", "BRCA1-associated 2 [IPR011422]", "BRCT domain [IPR001357]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHAT domain [IPR024983]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COMMD1 N-terminal domain [IPR033776]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cactin, C-terminal [IPR019134]", "Cactin, central domain [IPR018816]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain [IPR032880]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium-dependent channel, 7TM region, putative phosphate [IPR003864]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Caudal-like activation domain [IPR006820]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin II complex subunit H2, N-terminal [IPR009378]", "Condensin II complex subunit H2, middle domain [IPR031719]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Condensin-2 complex subunit H2, C-terminal [IPR031737]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Cortactin-binding protein-2, N-terminal [IPR019131]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIS3-like exonuclease 2, C-terminal [IPR041093]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dihydroorotate dehydrogenase domain [IPR005720]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disintegrin domain [IPR001762]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4592 [IPR028030]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF220, RING finger [IPR040178]", "E3 ubiquitin-protein ligase RNF220, middle domain [IPR031824]", "E3 ubiquitin-protein ligase UBR-like, C-terminal [IPR044046]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM83, N-terminal [IPR012461]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FCP1-like phosphatase, C-terminal [IPR015388]", "FCP1-like phosphatase, phosphatase domain [IPR011947]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHF complex subunit HOOK interacting protein, C-terminal [IPR045669]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Fascin domain [IPR022768]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Furin-like cysteine-rich domain [IPR006211]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G2 and S phase-expressed protein 1, N-terminal [IPR032768]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GDAP2, macro domain [IPR035793]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gasdermin, PUB domain [IPR041263]", "Gasdermin, pore forming domain [IPR040460]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyl transferase, family 28, C-terminal [IPR007235]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth factor receptor domain 4 [IPR032778]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HEPN domain [IPR007842]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl tRNA synthetase-related domain [IPR024435]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homeobox protein Hox1A3 N-terminal [IPR022067]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxyacylglutathione hydrolase, C-terminal domain [IPR032282]", "Hydroxyacylglutathione hydrolase, MBL domain [IPR035680]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISG20, DEDDh 3'-5' exonuclease domain [IPR037433]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Int12, PHD finger [IPR039054]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon gamma receptor, poxvirus/mammal [IPR021126]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIR motif [IPR016093]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Muskelin, N-terminal [IPR010565]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-end aminoacyl transferase, N-terminal [IPR007471]", "N-end rule aminoacyl transferase, C-terminal [IPR007472]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH dehydrogenase subunit 5, C-terminal [IPR010934]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal [IPR001516]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFA6, LYR domain [IPR045299]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NEMO, Zinc finger [IPR034735]", "NET domain [IPR027353]", "NF-kappa-B essential modulator NEMO, CC2-LZ domain [IPR032419]", "NF-kappa-B essential modulator NEMO, N-terminal [IPR021063]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OST-HTH/LOTUS domain [IPR025605]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-beta, PH domain [IPR037862]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C1A, propeptide [IPR012599]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M12B, ADAM/reprolysin [IPR001590]", "Peptidase M12B, propeptide [IPR002870]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phosphoinositide-specific phospholipase C, EF-hand-like domain [IPR015359]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase C-beta, C-terminal domain [IPR014815]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-mRNA-splicing factor SLU7 domain [IPR021715]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein RMD5 homologue A, degenerated RING finger [IPR037680]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM8, RNA recognition motif [IPR033744]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II assembly factor Rtp1, C-terminal [IPR019451]", "RNA polymerase II assembly factor Rtp1, C-terminal domain 2 [IPR019414]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "RecQ helicase-like 5 [IPR010716]", "Receptor L-domain [IPR000494]", "Redoxin [IPR013740]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease H2 subunit B, wHTH domain [IPR019024]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Rnh202, triple barrel domain [IPR041195]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SCAF4, RNA recognition motif [IPR034369]", "SCAN domain [IPR003309]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIR2-like domain [IPR039444]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SOCS box domain [IPR001496]", "SPF45, RNA recognition motif [IPR034653]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-8, SNARE domain [IPR041875]", "TANK binding kinase 1, ubiquitin-like domain [IPR041087]", "TANK-binding kinase 1, coiled-coil domain 1 [IPR041309]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBC1D8B, PH-GRAM domain 1 [IPR036012]", "TBC1D8B, PH-GRAM domain 2 [IPR036015]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TDRD7, third LOTUS domain [IPR037978]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRIM4, PRY/SPRY domain [IPR035829]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "TauD/TfdA-like domain [IPR003819]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thg1 C-terminal domain [IPR025845]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone C, N-terminal [IPR031925]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vesicle transport v-SNARE, N-terminal [IPR007705]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASP family, EVH1 domain [IPR033927]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WIBG, Mago-binding [IPR015362]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, SWIM-type [IPR007527]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA decapping enzyme 2 , NUDIX hydrolase domain [IPR044099]", "mRNA decapping protein 2, Box A domain [IPR007722]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNAHis guanylyltransferase catalytic domain [IPR024956]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "APMAP", "APOBEC3C", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC10", "ARMC9", "ARMCX3", "ARMT1", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BCAP31", "BCOR", "BCS1L", "BIRC6", "BLM", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "C2CD5", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC88A", "CCDC97", "CCNA2", "CCNB1", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDKAL1", "CDKN2AIP", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPV", "CEP170", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLUH", "CMBL", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT3", "CNPY2", "COA3", "COASY", "COG2", "COG4", "COIL", "COLEC12", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCP1A", "DCP1B", "DCP2", "DCTD", "DCTN1", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHODH", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "EMC1", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM118B", "FAM160A2", "FAM208A", "FAM49B", "FAM83D", "FANCA", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "ISYNA1", "ITCH", "ITGB1", "ITSN2", "IVD", "IWS1", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1211", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KIN", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC47", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MEPCE", "METAP1", "METAP2", "METTL13", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGME1", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL2", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL58", "MRPL9", "MRPS10", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NACC1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH2", "NCBP1", "NCL", "NCLN", "NCOR1", "NCSTN", "ND5", "NDC80", "NDUFA10", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PDZD8", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KB", "PICALM", "PIGG", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLAA", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCL1", "RCN1", "RCN2", "RDX", "RECQL", "RECQL4", "RECQL5", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOX1", "RIOX2", "RIPK1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RSL24D1", "RTCA", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A4", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STRN", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAGLN2", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THG1L", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKFC", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM63A", "TMEM97", "TMF1", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSR1", "TTC28", "TTC4", "TTF2", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UHRF1BP1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS29", "VPS37C", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WASL", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WNK2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YBX1", "YBX3", "YIPF4", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZYX"], "leading_proteins": ["AARS2", "AARSD1", "ABCC4", "ACLY", "ACOT13", "ADH5", "AFG3L2", "AKT1", "ALCAM", "ALG5", "ALYREF", "ANK3", "AP1B1", "AP2A1", "ARF6", "ARHGAP1", "ARL8B", "ASCC1", "ASCC3", "ATP2A2", "ATP2B1", "ATRX", "BLM", "BRD2", "BRIX1", "BSG", "BUB1", "BUD23", "CACUL1", "CADM1", "CAP2", "CDC42", "CDC42BPB", "CDC5L", "CELF1", "CEP170", "CHAF1B", "CHD4", "CIZ1", "CSTF2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "DDB1", "DDX10", "DDX18", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX42", "DDX46", "DDX47", "DDX49", "DDX50", "DDX54", "DDX55", "DDX56", "DGCR8", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX9", "DICER1", "DLAT", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC10", "DNAJC9", "DRG1", "DRG2", "EARS2", "ECT2", "EEF1E1", "EFTUD2", "EIF3F", "EIF3G", "EIF4H", "EIF5B", "EPB41L2", "EPB41L5", "EPN1", "EPRS", "ERAL1", "ERCC6L", "EXOSC10", "EXOSC2", "EXOSC6", "EXOSC9", "F11R", "FASTKD2", "FASTKD5", "FOXRED1", "G3BP2", "GDAP2", "GFM1", "GGA1", "GLRX3", "GMPPA", "GNL2", "GNL3", "GOT2", "GPKOW", "GPT2", "GRSF1", "GSTA4", "GTPBP10", "GTPBP3", "GTPBP4", "H1F0", "H1FX", "H2AFY2", "HIST1H1C", "HIST1H1E", "HLA-C", "HLTF", "HNRNPD", "HNRNPL", "HNRNPM", "HNRNPUL1", "HP1BP3", "HSDL2", "IARS", "IGF2BP2", "ILF2", "ILF3", "ILVBL", "IMPDH2", "KARS", "KIF1B", "LARP4", "LARP4B", "LARP7", "LARS2", "LPGAT1", "LSM6", "LYPLAL1", "MAK16", "MCCC1", "MDC1", "MKI67", "MOSPD2", "MPST", "MRPL16", "MRPL44", "MSI1", "MTA1", "MTA2", "MTHFD1L", "MYEF2", "MYO18A", "MYO1C", "NARS", "NAT10", "NBN", "NHLRC2", "NIFK", "NKRF", "NLN", "NOC3L", "NOL10", "NONO", "NOP56", "NRBP1", "NSUN6", "OGDH", "PABPN1", "PACSIN3", "PC", "PCCA", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDK3", "PDPR", "PELO", "PFKL", "PFKM", "PGLS", "PGM3", "PHF3", "PI4KB", "PINX1", "PNPT1", "POLDIP3", "POLR2A", "POLR2G", "PPIC", "PPIE", "PPIF", "PPIL1", "PPIL3", "PPP1CB", "PPP1R10", "PPP1R8", "PPWD1", "PRDX3", "PRDX4", "PRDX6", "PRRC2C", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA7", "PSMC1", "PSMC3", "PSMD14", "PTBP1", "PTBP2", "PTCD1", "PTK7", "PTPRF", "PYCR1", "RAB13", "RAB18", "RAB1A", "RAB2A", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5C", "RAB8B", "RAD23A", "RANBP1", "RAVER1", "RBBP6", "RBBP7", "RBM12B", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM28", "RBM34", "RBM42", "RBM47", "REXO4", "RFC4", "RFC5", "RHEB", "RHOT1", "RMND5A", "RP2", "RPF1", "RPF2", "RPL12", "RPL26", "RPL27", "RPL7L1", "RPLP0", "RPS20", "RPS4X", "RPS9", "RSL24D1", "SACS", "SAFB", "SAFB2", "SARNP", "SCO2", "SCP2", "SEC22B", "SF3A2", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SLC3A2", "SLTM", "SMAP2", "SMARCA1", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMC2", "SMC6", "SMCHD1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD3", "SNRPE", "SNU13", "SPHK2", "SPTBN2", "SRCAP", "SREK1", "SRP54", "SRRM2", "SRSF6", "SRSF9", "SSB", "STAU1", "STRBP", "STX12", "STX7", "SUCLA2", "SUN1", "SUPT16H", "SUPV3L1", "TARDBP", "TERF2", "THUMPD1", "TIA1", "TIAL1", "TIMM8A", "TIMM8B", "TMX1", "TMX2", "TMX3", "TOP2B", "TRA2A", "TRIO", "TRMT1", "TTF2", "TUFM", "TXNDC5", "TXNDC9", "TXNL1", "UBE3A", "VAPA", "VARS2", "VAT1", "WDR43", "XPNPEP1", "XPNPEP3", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC3", "ZCRB1", "ZFR", "ZMYM2", "ZNF318", "ZNF512B", "ZNF622"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..532c5c21dc7a67f9544bedf10f65bc6709844997 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Small GTPase [IPR001806]", "1": "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "2": "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "3": "Proteasome alpha-type subunit [IPR023332]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..687784c9c9cbac9b43f737172b4b9060c9d3d430 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7c2fedd4a6656324a19766603e445451bba7fcb6d4ff7b71f74f9d23bef28bad +size 134575 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..56229c09765f64c4668d43c36feb0a8df41303ea --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fdd14d7f45bcc023e50699591a5b59f220d2bf074565a72faa49f7aa248c91a5 +size 142518 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..985844c3b9f93f03e1950cfb89783b6e381f42ef --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7da94808a6b2296ae75e59d2f4c7006b7ce523f62faf239c4d4b921cd92fc849 +size 144202 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d55de591e4188ecfcf2bdc637003f3699fa0e02d --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c1bbbae39a603895e4e0584ac7eefdae1adc46a94b422565d696ac2e043c133 +size 147632 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..fbe451f99ea357849eca8f701f8e0697e97d2dc1 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86aa4af7fe46b5740793c2e955a21c0415a740e0d3595fce0aadc5b27b898954 +size 200091 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4e53103ce56aff7b7b72ec35deb42f0eec1cb994 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Linker histone H1/H5 [IPR005819] 4 5 2.2962509207660986 0.0216615385510485 4.014563106796117 4.956310679611651 -1.4175513233889876 0.1832168833940027 1.2501578748449933 0.257006630911632 1.3241307402406013 0.2675502959031997 1.0 0.0574361921538736 0.0002757976371321 1.601848804575542e-06 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fd2a67459219772ca35f6390d1cecf5c1966ad9c --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 2529, + "title": "Average number of proteins per term", + "value": 1.2882562277580072 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c7f1c5fc14e3a2866487736518244ef68585de22 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..75745daa7a6e5d6a86107577066e038a1263250b --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,100 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Linker histone H1/H5 [IPR005819] 0.8835244417622193 2.2962509207660986 0.0216615385510485 1.0 0.3875689439349444 5 P10412,Q92522,P07305,P16403 4 +Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492] 0.9056318832024678 1.8494706262869185 0.0643898854612197 1.0 0.3903184441127392 3 P55769 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.8935464414957742 1.8035261535511495 0.0713056218446566 1.0 0.3947079943519649 3 Q96BP3,Q9H2H8 2 +Ezrin/radixin/moesin-like [IPR000798] 0.7251040328025645 1.7439534645840813 0.0811672046809963 1.0 0.3976825793473308 6 Q9HCM4,O43491 2 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936] 0.8593056158337633 1.6725470451111537 0.0944164991186364 1.0 0.4104798187897276 3 Q9H2H8 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.8403759978987801 1.5996833440611111 0.1096688486784687 1.0 0.4315068852229513 3 Q9H6H4 1 +Mitochondrial carrier protein [IPR002067] 0.5586897858972435 1.4002240582810102 0.1614462336331517 1.0 0.5009450964103033 10 O43808,Q8TBP6 2 +Histone H2A [IPR002119] 0.7842936760685013 1.3824721205179205 0.166826785045639 1.0 0.5064848561444227 3 Q9P0M6 1 +Pre-mRNA-splicing factor Syf1-like [IPR045075] 0.7540289470548498 1.2648790137586672 0.2059147014058668 1.0 0.5566925904091209 3 Q9BZJ0 1 +Ribosomal protein L1/ribosomal biogenesis protein [IPR028364] 0.7535341147091668 1.2629569143354444 0.2066046642497152 1.0 0.5573415787668095 3 O76021 1 +Small GTPase [IPR001806] 0.4590024744588118 1.245327131015333 0.213011526646734 1.0 0.5635001578342996 36 Q92930,Q9NP72,Q15286,P51148,P61006,P20339,P61019,P60953,P51153,Q9BZG1,P62820,Q15382,P20338 13 +Bcl-2 family [IPR026298] 0.7458156158624492 1.2329841044068384 0.2175816947153128 1.0 0.5672825834381713 3 Q07820 1 +Bcl2-like [IPR002475] 0.7458156158624492 1.2329841044068384 0.2175816947153128 1.0 0.5672825834381713 3 Q07820 1 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.665468504214758 1.170416430813616 0.2418334266268686 1.0 0.5980385580621853 4 Q8TEA1 1 +DNA-directed RNA polymerase, subunit beta-prime [IPR045867] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.6692143631347764 3 P24928 1 +26S proteasome regulatory subunit P45-like [IPR005937] 0.5456944171309464 0.9503088627979692 0.3419553368596073 1.0 0.7031850798244645 6 P62191,P35998,P17980 3 +Core histone macro-H2A [IPR021171] 0.922520349713596 0.9177165734841513 0.3587672685731413 1.0 0.7200971604932337 2 Q9P0M6 1 +Isocitrate dehydrogenase NAD-dependent [IPR004434] 0.6354041013268947 0.8113055748960023 0.4171902093412036 1.0 0.7699640921616011 3 O43837,P50213 2 +Ribosomal protein L10P [IPR001790] 0.6332931242460812 0.803496139365092 0.4216880272805019 1.0 0.7739107554371476 3 Q9UKD2,P05388 2 +Ribosomal protein L24e-related [IPR000988] 0.8839312631896271 0.7928389453514675 0.4278716628315244 1.0 0.7761999810923611 2 Q9UHA3 1 +Small GTPase Rho [IPR003578] 0.5021791316599267 0.7622143898422922 0.4459320590929658 1.0 0.7897494239818702 6 P61586,P60953,Q8IXI2 3 +Syntaxin [IPR045242] 0.515868945460822 0.7357466015283035 0.4618849234907101 1.0 0.8030677054963533 5 Q9UNK0,O15400,Q86Y82 3 +Calreticulin/calnexin [IPR001580] 0.6145958986731004 0.7350221900230031 0.4623259800594232 1.0 0.8030677054963533 3 O14967,P27797 2 +High mobility group protein HMGN [IPR000079] 0.856798311727456 0.7077090753258866 0.4791259404598089 1.0 0.8113588312019748 2 P05114 1 +Peptidyl-tRNA hydrolase, PTH2 [IPR002833] 0.8504672897196184 0.6882275024674209 0.4913095273416425 1.0 0.8217095209666646 2 Q6GMV3 1 +Tricarboxylate/iron carrier [IPR004686] 0.5990755467716693 0.6792649190088103 0.4969700200683877 1.0 0.8245817712496418 3 Q6P4A7 1 +Ribosomal protein S15 [IPR000589] 0.8426288815194443 0.6643286522824128 0.5064799865351302 1.0 0.8308181117496807 2 P62277 1 +HnRNP-L/PTB [IPR006536] 0.5336349924585234 0.6463962980385538 0.5180227372641091 1.0 0.8402226750255997 4 P26599,Q9UKA9,P14866 3 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.8332830871269238 0.63617168923921 0.5246645235381795 1.0 0.8473030523806232 2 O60884 1 +Chaperone DnaJ [IPR012724] 0.5728033163321575 0.5876172206744491 0.5567892495820479 1.0 0.8681381086270031 3 O60884 1 +Inositol monophosphatase-like [IPR000760] 0.570897229414133 0.5811208955171628 0.561158976635475 1.0 0.8716343194084197 3 Q9NX62 1 +SUN domain-containing protein 1-5 [IPR045119] 0.8085619535724982 0.5636376231393179 0.5730007765216611 1.0 0.8764629456945727 2 O94901 1 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.3919630105830177 0.5597258957026771 0.5756664162782976 1.0 0.8764629456945727 10 P62330 1 +Synaptobrevin [IPR001388] 0.8019294543261943 0.544700758976403 0.5859593427621068 1.0 0.8841832803373317 2 O75396 1 +Succinate--CoA synthetase, beta subunit [IPR005809] 0.8004220681338577 0.5404299120610901 0.5889005840170825 1.0 0.885978332527782 2 Q9P2R7 1 +RNA-binding protein 26/27 [IPR045137] 0.7913777509797976 0.5150700654493626 0.6065040597955795 1.0 0.8938512629504782 2 Q9P2N5 1 +Protein disulphide isomerase [IPR005792] 0.5446320868516256 0.4940598450510958 0.6212639155298638 1.0 0.8993568645535349 3 P30101,P13667 2 +Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141] 0.7829363883026721 0.4918260447492941 0.6228423230225573 1.0 0.9000782374895573 2 P62314 1 +Microtubule associated protein 1 [IPR026074] 0.5370458925231014 0.469850086861482 0.6384621268774084 1.0 0.9073571257427646 3 Q66K74 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.5370138048683897 0.4697486542433289 0.6385346023097518 1.0 0.9073571257427646 3 P05141 1 +Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312] 0.5367959386930704 0.4690601749998155 0.6390266243683496 1.0 0.9073571257427646 3 O43776 1 +Macrophage migration inhibitory factor [IPR001398] 0.7732891166716769 0.4657894680431617 0.6413662044789676 1.0 0.9081831641250332 2 P14174 1 +Phosphatidylinositol kinase [IPR015433] 0.5307105720143259 0.4499869191402224 0.6527198726088841 1.0 0.9099793399999092 3 Q9UBF8 1 +DNA topoisomerase II, eukaryotic-type [IPR001154] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 0.913738428378712 2 Q02880 1 +DNA topoisomerase, type IIA [IPR001241] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 0.913738428378712 2 Q02880 1 +SURP and G-patch domain-containing protein 1/2 [IPR040169] 0.7497738920711361 0.4048586101522254 0.6855814438692485 1.0 0.9223949452375678 2 Q8IWZ8 1 +Protein PRRC2 [IPR033184] 0.5133764404800183 0.3974113921841519 0.6910641160113542 1.0 0.9256369137380152 3 Q9Y520 1 +Ran binding protein RanBP1-like [IPR045255] 0.4570887300068019 0.3818091087097023 0.7026029619476919 1.0 0.9323015289487696 4 P43487 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.7398251432016784 0.3802376460298192 0.7037690166265689 1.0 0.9323015289487696 2 O43819 1 +Copper chaperone SCO1/SenC [IPR003782] 0.7398251432016784 0.3802376460298192 0.7037690166265689 1.0 0.9323015289487696 2 O43819 1 +Pyrroline-5-carboxylate reductase [IPR000304] 0.7283690081398876 0.352795490484485 0.7242417647517789 1.0 0.9418085612337448 2 P32322 1 +Peptidase M3A/M3B [IPR045090] 0.4967983560527889 0.3497730636256323 0.7265090157788934 1.0 0.9418085612337448 3 Q9BYT8 1 +Erlin1/2 [IPR033294] 0.7244498040397904 0.3436383775712124 0.7311182592771537 1.0 0.942319070045873 2 O75477 1 +Structural maintenance of chromosomes protein [IPR024704] 0.4436444066214153 0.3410183500140922 0.7330897675611967 1.0 0.9425183623891328 4 O95347 1 +Adaptor protein complex AP-2, alpha subunit [IPR017104] 0.7214350316551122 0.3366764217197025 0.7363608394746652 1.0 0.9443491698942336 2 O95782 1 +Ribosomal protein L3 [IPR000597] 0.7199276454627594 0.3332224442939593 0.73896637723738 1.0 0.946208979995226 2 P39023 1 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.7090744648778934 0.308894528343147 0.7574017591631959 1.0 0.950895893156552 2 Q9P0I2 1 +Ribosomal protein S17/S11 [IPR000266] 0.7075670786855552 0.3055918890343328 0.7599153968473176 1.0 0.9521823199304862 2 P62280 1 +Ribosomal protein L11/L12 [IPR000911] 0.7069641242086224 0.3042761104582486 0.7609175439223064 1.0 0.9521823199304862 2 P30050 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.706361169731673 0.3029633556123643 0.7619177879280243 1.0 0.9526416280124445 2 O60220 1 +Mesoderm induction early response protein/metastasis-associated protein [IPR040138] 0.7051552607778087 0.3003469388357949 0.7639125329094623 1.0 0.9526416280124445 2 Q13330 1 +Ribosomal protein L7, eukaryotic [IPR005998] 0.7048537835393303 0.299694732934985 0.7644100165591479 1.0 0.9526416280124445 2 Q6DKI1 1 +Ribosomal protein L7/L30 [IPR039699] 0.7048537835393303 0.299694732934985 0.7644100165591479 1.0 0.9526416280124445 2 Q6DKI1 1 +Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423] 0.3350453172205451 0.2841671387069553 0.7762822973268002 1.0 0.9530093804894336 9 Q99832,P48643,P40227,P10809,P78371,P50990,P49368,P17987 8 +Glutathione Transferase family [IPR040079] 0.3239627294723192 0.2820332862235129 0.7779179871595061 1.0 0.9530093804894336 12 O15217,Q5HYI7 2 +Beta-catenin [IPR013284] 0.6837503768465436 0.2559667742778981 0.7979764931038673 1.0 0.9530093804894336 2 P14923 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672] 0.4577682693213992 0.2492675282134981 0.8031538474225592 1.0 0.9530093804894336 3 Q6UB35 1 +Adenylate cyclase-associated CAP [IPR001837] 0.6795296955079795 0.247686832025627 0.8043767209876216 1.0 0.9530093804894336 2 P40123 1 +Dynein light chain, type 1/2 [IPR001372] 0.6777208320771738 0.2441867662052574 0.8070861759326093 1.0 0.9530093804894336 2 Q96FJ2 1 +Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309] 0.6771178776002259 0.2430265698509691 0.8079848146040831 1.0 0.9530093804894336 2 O95478 1 +Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998] 0.3349441256417947 0.2430249653604612 0.8079860575498132 1.0 0.9530093804894336 8 Q99832,P48643,P40227,P78371,P50990,P49368,P17987 7 +Nucleolar, Nop52 [IPR010301] 0.6741031052155442 0.2372744450232608 0.8124438859989824 1.0 0.9530093804894336 2 Q14684 1 +Kinesin-like protein [IPR027640] 0.299887985730038 0.2254696058063718 0.8216139676945502 1.0 0.9530093804894336 10 O95235,O60333 2 +Valine-tRNA ligase [IPR002303] 0.6569189026228431 0.2060600447997466 0.8367440085974707 1.0 0.9530093804894336 2 Q5ST30 1 +F-actin-capping protein subunit alpha [IPR002189] 0.655712993668977 0.2039710621340179 0.8383761125799212 1.0 0.9530093804894336 2 P52907 1 +Mitochondrial Rho GTPase [IPR021181] 0.6505878806150103 0.1952427217143234 0.8452029354649784 1.0 0.9530093804894336 2 Q8IXI2 1 +Formate-tetrahydrofolate ligase, FTHFS [IPR000559] 0.6403376545070764 0.1785169314071246 0.858317025420398 1.0 0.9530093804894336 2 Q6UB35 1 +Vesicle-associated membrane-protein-associated protein [IPR016763] 0.638227313837797 0.17519475773667 0.8609266033506235 1.0 0.9530093804894336 2 Q9P0L0 1 +Actin family [IPR004000] 0.326940248672909 0.1601387941953582 0.8727717421468204 1.0 0.9530093804894336 6 Q9GZN1 1 +Peptidase, FtsH [IPR005936] 0.62827856496834 0.1600923662170392 0.8728083144937433 1.0 0.9530093804894336 2 Q9Y4W6 1 +Developmentally regulated GTP-binding protein [IPR045001] 0.6276756104914045 0.1592067276462049 0.8735060035744231 1.0 0.9530093804894336 2 P55039 1 +La domain containing protein [IPR045180] 0.3328304164152021 0.1436935607876169 0.8857424561759912 1.0 0.9530093804894336 5 P05455,Q4G0J3,Q92615,Q71RC2 4 +ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914] 0.3869119420989164 0.1152969081675203 0.9082097889458172 1.0 0.9536524435046648 3 P08237,P17858 2 +ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161] 0.3869119420989164 0.1152969081675203 0.9082097889458172 1.0 0.9536524435046648 3 P08237,P17858 2 +ATP-dependent 6-phosphofructokinase [IPR022953] 0.3869119420989164 0.1152969081675203 0.9082097889458172 1.0 0.9536524435046648 3 P08237,P17858 2 +Glutamyl/glutaminyl-tRNA synthetase [IPR000924] 0.384800965018096 0.1123217447477756 0.9105683010842812 1.0 0.954137460618549 3 Q5JPH6,P07814 2 +Histidine phosphatase superfamily, clade-1 [IPR013078] 0.3733413751507901 0.0971809031746533 0.9225827333136776 1.0 0.9580194107396706 3 Q96HS1,P18669 2 +Aldo-keto reductase [IPR020471] 0.5679831172746388 0.0879629806614739 0.9299060992034364 1.0 0.9583262122597762 2 P15121 1 +Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661] 0.5649683448899514 0.0851954942444868 0.9321059726314508 1.0 0.9590301077237344 2 O43683 1 +Citrate synthase [IPR002020] 0.5619535725052663 0.0825032099014187 0.9342465659065272 1.0 0.9608416287830852 2 O75390 1 +Proteasome alpha-type subunit [IPR023332] 0.2475845410627992 0.0593727635395072 0.952655206325401 1.0 0.9738097650127514 7 P25788,P25787,P25789,P28066,P25786,O14818 6 +Sulfotransferase [IPR005331] 0.5296955079891372 0.0581640738762874 0.953617937146964 1.0 0.9738097650127514 2 Q8NCH0 1 +Ribosomal protein S4/S9 [IPR022801] 0.5263792583659812 0.0560977390435215 0.9552639450860348 1.0 0.9749243410502751 2 P46781 1 +Prohibitin [IPR000163] 0.5227615315043622 0.0539298182877109 0.9569910796698172 1.0 0.9758993711632936 2 P35232 1 +Sorting nexin-5/6/32 [IPR014637] 0.5028640337654368 0.0435267970251434 0.9652816038268512 1.0 0.9815831025645784 2 Q9UNH7 1 +Lupus La protein [IPR002344] 0.49623153451913 0.0405925085179117 0.9676207565725534 1.0 0.983171110233824 2 Q4G0J3 1 +Inosine-5'-monophosphate dehydrogenase [IPR005990] 0.4947241483267888 0.0399602771288158 0.9681247952398452 1.0 0.9832881956472164 2 P12268 1 +UV excision repair protein Rad23 [IPR004806] 0.4895990352728242 0.0379033182118813 0.9697647674014198 1.0 0.984163361459948 2 P54725 1 +Peroxiredoxin, AhpC-type [IPR024706] 0.3873982514320128 0.0182502504243109 0.9854392152575532 1.0 0.994304096535386 2 P30041 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d709d5a5778ab36395b696baa3c43cd0f077cf51 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S10, mitochondrial [IPR040055]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6 [IPR041839]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acetoacetyl-CoA synthase [IPR005914]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Actin-related protein 6 [IPR030054]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating transcription factor 7-interacting protein [IPR026085]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl cyclase-associated protein CAP2 [IPR028418]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkylated DNA repair protein AlkB [IPR004574]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Arginine-tRNA-protein transferase 1, eukaryotic [IPR017137]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2 [IPR033093]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCP1 family [IPR025602]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biogenesis of lysosome-related organelles complex 1 subunit 1 [IPR009395]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 1 [IPR037351]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 2 [IPR037354]", "COMM domain-containing protein 7 [IPR037358]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CSC1-like protein 1 [IPR026957]", "CTD phosphatase Fcp1 [IPR039189]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium permeable stress-gated cation channel 1-like [IPR045122]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-2 [IPR035702]", "Caspase-3/7 [IPR015471]", "Cat eye syndrome critical region protein 2 [IPR029614]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein I [IPR012485]", "Centromere protein U [IPR025214]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceramide glucosyltransferase [IPR025993]", "Cerebellar degeneration-related protein 2 [IPR026079]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Ceroid-lipofuscinosis neuronal protein 6 [IPR029255]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin modification-related protein Eaf6 [IPR015418]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Chromosome transmission fidelity protein 8 [IPR018607]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 43 [IPR037666]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit G2 [IPR024741]", "Condensin-2 complex subunit H2 [IPR031739]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DIS3-like exonuclease 2 [IPR028591]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA replication/checkpoint protein [IPR021110]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydroorotate dehydrogenase, class 2 [IPR005719]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase UBR1-like [IPR039164]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FHF complex subunit HOOK interacting protein [IPR019384]", "FUN14 [IPR007014]", "Family of unknown function DUF5525 [IPR037656]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv10 family [IPR045098]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "G2 and S phase-expressed protein 1 [IPR026659]", "GDP dissociation inhibitor [IPR018203]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOLM1/CASC4 family [IPR026139]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI transamidase component PIG-T [IPR007245]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "Galactokinase [IPR000705]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-glutamyltranspeptidase [IPR000101]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gasdermin-E [IPR042377]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "Gemini of Cajal bodies-associated protein 8 [IPR034754]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-1 subunit beta [IPR041960]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Girdin [IPR027717]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, alpha class [IPR003080]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi membrane protein 1 [IPR026143]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 2 [IPR028346]", "HAUS augmin-like complex subunit 2, metazoa [IPR026242]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HIRA-interacting protein 3 [IPR037647]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxyacylglutathione hydrolase [IPR017782]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "I-BAR domain containing protein MTSS1/MTSS2 [IPR030127]", "I-BAR domain containing protein MTSS2 [IPR030059]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase [IPR033942]", "Inositol monophosphatase, lithium-sensitive [IPR020552]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 12 [IPR039053]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon gamma receptor alpha subunit [IPR008355]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-stimulated 20kDa exonuclease-like 2 [IPR034933]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isochorismatase domain-containing protein 2 [IPR040318]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF15/KIN-12E [IPR044986]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine carboxyl methyltransferase 1 [IPR016651]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Liprin-alpha-1 [IPR030438]", "LisH domain-containing protein ARMC9 [IPR040369]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICAL-like protein [IPR028563]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate kinase [IPR006205]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial intermembrane space import and assembly protein 40 [IPR039289]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-acetyltransferase Ard1-like [IPR045047]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-end rule aminoacyl transferase [IPR030700]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-plastoquinone oxidoreductase, chain 5 subgroup [IPR018393]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain 5-like [IPR003945]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural Wiskott-Aldrich syndrome protein [IPR030214]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuroplastin [IPR027112]", "Neutral amino acid SLC6 transporter [IPR002438]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear factor NF-kappa-B, p105 subunit [IPR030503]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ORC ubiquitin ligase 1 [IPR039209]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PAX-interacting protein 1 [IPR037886]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PNN-interacting serine/arginine-rich protein [IPR031937]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Partner of Y14 and mago [IPR039333]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol 3-kinase, Vps34 type [IPR008290]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta [IPR016280]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphoserine phosphatase [IPR004469]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SLU7 [IPR039974]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1 [IPR026657]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM118 [IPR038916]", "Protein FAM118B [IPR033352]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein NDRG3 [IPR030692]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF2452 [IPR019534]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein strawberry notch [IPR026741]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, RluC/RluD [IPR006225]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Putative RNA-binding protein 47 [IPR034442]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cap guanine-N2 methyltransferase [IPR019012]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-1 [IPR033086]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Ran-interacting Mog1 protein [IPR007681]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho GDP/GTP exchange factor Kalirin/TRIO [IPR028570]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2 subunit B [IPR040456]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAFB-like transcription modulator [IPR034780]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase MARK1 [IPR033627]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Sm-like protein Lsm6/SmF [IPR016487]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 1 [IPR009829]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Spindle assembly checkpoint component Mad1 [IPR008672]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex 11 [IPR008862]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TANGO6/Rtp1 [IPR039600]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TEL2-interacting protein 1 [IPR016441]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TOX high mobility group box family member 4 [IPR037985]", "TPMT family [IPR008854]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thiopurine S-methyltransferase [IPR025835]", "Thioredoxin [IPR005746]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription termination factor, mitochondrial/chloroplastic [IPR003690]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery associated TMA7 [IPR015157]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone C [IPR027684]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine protein kinase, EGF/ERB/XmrK receptor [IPR016245]", "Tyrosine-protein kinase, insulin-like receptor [IPR016246]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1-binding protein 1-like [IPR026728]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0687 [IPR026794]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar import/degradation protein Vid24 [IPR018618]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 3 [IPR019309]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR48/Bun107 [IPR021772]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "Yos1-like [IPR013880]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "eIF-2-alpha kinase Gcn2 [IPR016255]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-specific 2-thiouridylase [IPR004506]", "tRNAHis guanylyltransferase Thg1 [IPR007537]"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALKBH1", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANKLE2", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEX1", "API5", "APOO", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARFIP2", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMC9", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BASP1", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf50", "C20orf27", "C21orf59", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC88A", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDR2L", "CDS2", "CDV3", "CEBPZ", "CECR2", "CENPB", "CENPI", "CENPU", "CEP170", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1L", "CHD8", "CHERP", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF8", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLGALT1", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EGFR", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAH", "FAM114A1", "FAM114A2", "FAM118B", "FAM160A2", "FAM162A", "FAM177A1", "FAM213A", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTB", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID4", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMFB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPT2", "GRPEL1", "GRSF1", "GSDME", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDHD2", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO4", "IPO5", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LONP1", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK1", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGST2", "MGST3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCLN", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NFKB1", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NSA2", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PAXIP1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PLA2G15", "PLBD2", "PLCB3", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PTRHD1", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM47", "RBM5", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF40", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SBNO1", "SCAF1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC6A15", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMCHD1", "SMG8", "SMPD4", "SMS", "SMU1", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCC", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TECR", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", 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0000000000000000000000000000000000000000..08df22da12b0e59736ff025dc477fef306369d6c --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c05ca057e66600201bf5a8843bbd6a20a78c6d3184ca64c9a2f93aec05449770 +size 152851 diff --git a/interpro_homologous_superfamily/basic/plot_9.png b/interpro_homologous_superfamily/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..a5e74a9c3cd89e30d74febd5d8eb97bb3eb5a65f --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c21cd35683da27cbdbce9a1c59dfb39d7cd77a10f7bfdcdcc4d3795aea155e27 +size 145272 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a017ef72a08f110b4f2fe4569d6d2b86874fa2d7 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8486f1a5a5aa17b2147eddbaf029faf2e47a3bcb02a3ad9275064a57de279c71 +size 108551 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1d1599e1b197bc1ec88b1040901b00197d64bfad --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Rudiment single hybrid motif [IPR011054] 2 6 2.271307844330299 0.0231283487000741 4.592233009708738 5.890776699029126 -1.9937427767755864 0.0922188338858135 0.9210261605540432 0.311919174620445 1.449370829194519 0.2206040317774329 1.0 0.0574361921538736 0.0002757976371321 0.0020977388537863 +Translation protein SH3-like domain superfamily [IPR008991] 5 10 2.1522333235410107 0.0313789822925765 5.533980582524272 10.04126213592233 -0.6036748352654394 0.3877498786779733 2.367110950515448 0.8189185143996353 1.121702761763535 0.314654675983089 0.0619434524836269 0.1203280145079081 0.0390924086837951 0.0002576459081604 +Pre-ATP-grasp domain superfamily [IPR016185] 2 8 2.084359695904705 0.0371274610597049 4.890776699029126 7.871359223300971 -2.05233613048585 0.1042945789544412 1.0544461476490947 0.3821948584080789 1.4268170383063945 0.2366644135195186 1.0 0.1116045715736199 0.0027195691326621 0.0185110547795427 +Single hybrid motif [IPR011053] 4 8 2.0659134840744726 0.0388366494202898 5.182038834951456 8.361650485436893 -2.130161056715037 0.0953326994482326 1.4807396860722422 0.6846338360686358 1.3497960821287889 0.2162773212056401 1.0 0.1027954944442906 0.0020770710993276 0.0014308257294634 +Ribosomal protein L2, domain 2 [IPR014722] 4 11 2.0624630033868 0.0391636763568465 5.737864077669903 11.25 -0.6609982231548526 0.3931826402266836 2.497420669599456 1.4740884957165508 1.0649776696651303 0.3158800401167336 0.0802348466038066 0.1543818096433915 0.3445026949300507 0.0477467344295515 +50S ribosomal protein L30e-like [IPR029064] 1 7 2.0435019268589865 0.0410027768249166 3.737864077669903 7.162621359223301 -0.6671333648895198 0.4266161356127039 1.8246487362370143 0.9374935196307274 0.9002904128425242 0.2970347916697464 0.0573151884822011 0.1116045715736199 0.2577455317022596 0.1144905971504207 +Exoribonuclease, PH domain 2 superfamily [IPR036345] 3 6 1.9732013320516315 0.0484726287840486 3.4757281553398056 5.970873786407767 -0.7224223652638475 0.4516190241506664 1.6813925123151383 0.90528449296138 0.8042796304231143 0.311821944199576 1.0 1.0 1.0 0.0427743402023459 +PNPase/RNase PH domain superfamily [IPR027408] 3 6 1.9732013320516315 0.0484726287840486 3.4757281553398056 5.970873786407767 -0.7224223652638475 0.4516190241506664 1.6813925123151383 0.90528449296138 0.8042796304231143 0.311821944199576 1.0 1.0 1.0 0.0427743402023459 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a2ee54ed5cb0923d6cf799e7e680c4841a593f35 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 993, + "title": "Average number of proteins per term", + "value": 4.899295065458207 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7708d4cf7059bcb9e12d5141cad5215a04a8e58b --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1b72b7644bcf93b1703897bc96fdc337be9fded4 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,157 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Rudiment single hybrid motif [IPR011054] 0.849297950217933 2.271307844330299 0.0231283487000741 0.9999999999189704 0.5598604555159711 6 Q96RQ3,P05165 2 +Translation protein SH3-like domain superfamily [IPR008991] 0.7042226166283275 2.1522333235410107 0.0313789822925765 0.9999999999999822 0.5598604555159711 10 Q5T653,P62917,P49406,Q02878,P61353 5 +Pre-ATP-grasp domain superfamily [IPR016185] 0.7504694807572476 2.0843596959047055 0.0371274610597049 1.0 0.5598604555159711 8 Q96RQ3,P05165 2 +Single hybrid motif [IPR011053] 0.7464514888710236 2.0659134840744726 0.0388366494202898 1.0 0.5598604555159711 8 Q96RQ3,P11498,P05165,P10515 4 +Ribosomal protein L2, domain 2 [IPR014722] 0.6865140459178337 2.0624630033868 0.0391636763568465 1.0 0.5598604555159711 11 Q5T653,Q02878,P50914,P62917 4 +50S ribosomal protein L30e-like [IPR029064] 0.7689218157742529 2.0435019268589865 0.0410027768249166 1.0 0.5598604555159711 7 P55769 1 +Exoribonuclease, PH domain 2 superfamily [IPR036345] 0.7782980312909 1.9732013320516313 0.0484726287840486 1.0 0.5598604555159711 6 Q5RKV6,Q06265,Q8TCS8 3 +PNPase/RNase PH domain superfamily [IPR027408] 0.7782980312909 1.9732013320516313 0.0484726287840486 1.0 0.5598604555159711 6 Q5RKV6,Q06265,Q8TCS8 3 +Macro domain-like [IPR043472] 0.8016156367316664 1.9594584326702416 0.0500591233128524 1.0 0.5598604555159711 5 Q9P0M6,O75367,Q9NXN4 3 +Cyclophilin-like domain superfamily [IPR029000] 0.6582236954118619 1.9173083521619012 0.0551987694841622 1.0 0.5844463929898286 12 Q9Y3C6,Q96BP3,Q9UNP9,P30405,Q9H2H8,P45877 6 +FERM/acyl-CoA-binding protein superfamily [IPR014352] 0.6490492560167247 1.8717236556755696 0.0612448450740772 1.0 0.5844463929898286 10 Q9HCM4,Q9H3P7,O43491 3 +Chloramphenicol acetyltransferase-like domain superfamily [IPR023213] 0.7787706311106416 1.8634950704210056 0.0623926454553418 1.0 0.5844463929898286 5 P36957,P10515 2 +Immunoglobulin-like domain superfamily [IPR036179] 0.6441907311894622 1.84543350293164 0.0649745033177726 1.0 0.5844463929898286 13 P10586,P35613,P10321,Q13740,Q9Y624,Q13308,Q9BY67,O75962 8 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.8295792543696182 1.838971133108704 0.0659194320391347 1.0 0.5844463929898286 4 P62847,P61313 2 +FERM superfamily, second domain [IPR035963] 0.6822245552147654 1.7667563266031656 0.0772690456917957 1.0 0.6113407996551207 8 Q9HCM4,O43491 2 +CRAL-TRIO lipid binding domain superfamily [IPR036865] 0.737551253661398 1.6883398763546127 0.0913460046687917 1.0 0.635808837563195 5 O75962,Q07960 2 +NagB/RpiA transferase-like [IPR037171] 0.6770353326453156 1.6307842592677573 0.102935849965617 1.0 0.6619191489770465 7 Q9UI10 1 +Thiamin diphosphate-binding fold [IPR029061] 0.6839722306067023 1.5637083463937589 0.1178860767622898 1.0 0.6945722270549499 6 A1L0T0,Q02218,Q9UJ83,P08559,P11177 5 +Zinc finger, CCCH-type superfamily [IPR036855] 0.6494262064664017 1.5042870760099611 0.1325074653369213 1.0 0.6945722270549499 7 Q9NW64,Q96QC0,Q8WU90 3 +Winged helix-like DNA-binding domain superfamily [IPR036388] 0.4086767375172781 1.464653311685983 0.1430155289895012 1.0 0.6945722270549499 45 P10412,P16403,P54132,P13984,O14641,Q5SSJ5,Q92522,P07305 8 +Nucleic acid-binding, OB-fold [IPR012340] 0.4075117982949552 1.453740963807156 0.1460181365195718 1.0 0.6945722270549499 45 Q5T653,P62917,Q8TCS8,P33992,Q13868,Q6NSI4,P62280,P16989,P62857,P62266,P62487,Q15046,Q9Y2L1 13 +Zinc finger C2H2 superfamily [IPR036236] 0.5560712474538639 1.4085489346092452 0.1589685876238977 1.0 0.7008561633212805 20 P09234,Q15428,Q96KM6,Q9NX58,Q9ULV3,Q969S3 6 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.7853787422788325 1.3866868700364472 0.1655372660203391 1.0 0.7078555773079174 3 Q969Y2 1 +Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041] 0.594615570389633 1.3485232378861018 0.1774901512464053 1.0 0.7132523817990088 8 Q10567,O95782,Q9UJY5 3 +NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064] 0.7705066344994002 1.328903623850893 0.1838797681173678 1.0 0.7132523817990088 3 Q4G0N4,Q9NRA0 2 +Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438] 0.7705066344994002 1.328903623850893 0.1838797681173678 1.0 0.7132523817990088 3 Q4G0N4,Q9NRA0 2 +SMAD/FHA domain superfamily [IPR008984] 0.5449820899344308 1.3216893158182628 0.1862716278689076 1.0 0.7197187800537949 11 Q5SW79,O60333,O60934,Q12972,P46013,Q14676 6 +Ribosomal protein L1-like [IPR023674] 0.7535341147091668 1.2629569143354444 0.2066046642497152 1.0 0.7511908793190701 3 O76021 1 +Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095] 0.7535341147091668 1.2629569143354444 0.2066046642497152 1.0 0.7511908793190701 3 O76021 1 +PUA domain superfamily [IPR036974] 0.7485396603748509 1.2435602055117525 0.2136614698689161 1.0 0.7550385750172017 3 Q8TEA1 1 +Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149] 0.6823529411764716 1.2396955861238366 0.215088010349987 1.0 0.7551722209965381 4 Q9Y5B9,Q9NQH7,Q9NQW7 3 +Zinc finger, CCHC-type superfamily [IPR036875] 0.606429140365231 1.2194111269702517 0.2226881887978629 1.0 0.7613934113806753 6 Q8TBF4,Q9NUD5 2 +Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900] 0.7313134366546943 1.1767323932067018 0.239302334282256 1.0 0.7724045964348378 3 O95394 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055] 0.7313134366546943 1.1767323932067018 0.239302334282256 1.0 0.7724045964348378 3 O95394 1 +Succinyl-CoA synthetase-like [IPR016102] 0.6660212196453414 1.1726823025962123 0.2409232309330189 1.0 0.7724045964348378 4 Q9P2R7 1 +ARFGAP/RecO-like zinc finger [IPR037278] 0.6166393649026574 1.164782253892872 0.2441071439673536 1.0 0.7744357634491443 5 Q8WU79 1 +ArfGAP domain superfamily [IPR038508] 0.6166393649026574 1.164782253892872 0.2441071439673536 1.0 0.7744357634491443 5 Q8WU79 1 +Histone-fold [IPR009072] 0.5631190048071858 1.1059706773375717 0.2687392113194278 1.0 0.8075416186854962 7 Q9P0M6,P62805 2 +Winged helix DNA-binding domain superfamily [IPR036390] 0.360552968026573 1.1049516514391284 0.2691805395618321 1.0 0.8075416186854962 46 P10412,P16403,P54132,P13984,O14641,Q5SSJ5,Q92522,P07305 8 +RNA polymerase Rpb1, funnel domain superfamily [IPR038120] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.8494724192369865 3 P24928 1 +RNA polymerase Rpb1, domain 3 superfamily [IPR042102] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.8494724192369865 3 P24928 1 +RNA polymerase Rpb1, clamp domain superfamily [IPR044893] 0.6895025821092111 1.0155041546370924 0.3098655671138091 1.0 0.8494724192369865 3 P24928 1 +Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223] 0.688115575127922 1.0101924381575624 0.3124031014585944 1.0 0.8494724192369865 3 O75695 1 +Rho GTPase activation protein [IPR008936] 0.5046571070677168 1.009972026097361 0.3125086925900118 1.0 0.8494724192369865 9 Q13576 1 +LSM domain superfamily [IPR010920] 0.5007504790330698 0.9906829311906816 0.3218404282781133 1.0 0.8494724192369865 9 P62304,P62316,P62318,Q99700,P62314,P62312 6 +Zinc-binding ribosomal protein [IPR011332] 0.6826198676783726 0.9891767132666126 0.3225766896796327 1.0 0.8494724192369865 3 P83881 1 +Bcl-2-like superfamily [IPR036834] 0.6187385417998971 0.9798958179439796 0.327137547520995 1.0 0.8542741617886519 4 Q07820 1 +ENTH/VHS [IPR008942] 0.4793235652043469 0.9601316109734996 0.3369889808047661 1.0 0.8666118214969201 14 Q9Y6I3 1 +SCP2 sterol-binding domain superfamily [IPR036527] 0.6746079613992797 0.9586343617076982 0.3377429757495549 1.0 0.8666118214969201 3 Q6YN16,P22307 2 +Tim10-like domain superfamily [IPR035427] 0.6649577804583776 0.9220157092279796 0.35652038161831 1.0 0.8943895488378357 3 O60220,Q9Y5J9 2 +SNF2-like, N-terminal domain superfamily [IPR038718] 0.4716795329034143 0.919994409548218 0.3575756806531931 1.0 0.8943895488378357 14 P46100,P28370,Q14839,Q2NKX8,O60264,Q9H4L7,Q9UNY4,Q6ZRS2,Q14527 9 +ATP-grasp fold, subdomain 1 [IPR013815] 0.5182767865385458 0.9013486309564898 0.3674029846861273 1.0 0.904570643576216 7 Q9P2R7,P05165 2 +F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276] 0.6559107358262991 0.8878762014337337 0.3746073475030214 1.0 0.9094990123973112 3 P52907,P47756 2 +F-actin-capping protein subunit alpha/beta [IPR037282] 0.6559107358262991 0.8878762014337337 0.3746073475030214 1.0 0.9094990123973112 3 P52907,P47756 2 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.45721899697608 0.8634326197085648 0.3878996511261321 1.0 0.9344751051556508 22 Q8NBJ5,O43909,Q9Y673,Q8NFW8,O60568 5 +Longin-like domain superfamily [IPR011012] 0.4502719985132848 0.8281315469867936 0.4075960053211012 1.0 0.9363290857236076 11 P08240,O75396,Q9BXS5,O15498,P53680,Q9Y296,P51809 7 +Bromo adjacent homology (BAH) domain superfamily [IPR043151] 0.5798727013829864 0.8244418930341644 0.4096885194372923 1.0 0.9363290857236076 4 O94776,Q13330 2 +PapD-like superfamily [IPR008962] 0.638419782870935 0.8224871463911514 0.4107996991766411 1.0 0.9363290857236076 3 Q8NHP6,Q9P0L0 2 +SAP domain superfamily [IPR036361] 0.4488379345739491 0.8132633280980709 0.4160670977179557 1.0 0.9363290857236076 12 P55145,Q9NWH9,Q9BUJ2 3 +Ribosomal protein L10-like domain superfamily [IPR043141] 0.6332931242460812 0.803496139365092 0.4216880272805019 1.0 0.9388704284518798 3 Q9UKD2,P05388 2 +Ribosomal protein L24e/L24 superfamily [IPR038630] 0.8839312631896271 0.7928389453514675 0.4278716628315244 1.0 0.9407544586025514 2 Q9UHA3 1 +PUA-like superfamily [IPR015947] 0.4770509122853235 0.7908512602163885 0.4290307931117549 1.0 0.9407544586025514 8 Q8TEA1,Q9P016 2 +SMCs flexible hinge superfamily [IPR036277] 0.5158092386757248 0.7355018818875333 0.4620338942984641 1.0 0.9610541581792824 5 O95347,A6NHR9 2 +Calreticulin/calnexin, P domain superfamily [IPR009033] 0.6145958986731004 0.7350221900230031 0.4623259800594232 1.0 0.9610541581792824 3 O14967,P27797 2 +Immunoglobulin-like fold [IPR013783] 0.4003266453364775 0.7278102209366012 0.4667297669408741 1.0 0.9655472053589332 33 O75962,Q9P0L0,P10586,P10321,Q04446,P35613,Q13740,Q9Y624,P04439,Q13308,Q9BY67,Q7Z4H8 12 +Transcription elongation factor S-II, central domain superfamily [IPR036575] 0.6073427941334795 0.7088318739721692 0.4784288154649236 1.0 0.9702170960183076 3 Q92576 1 +Ribosomal protein S10 domain superfamily [IPR036838] 0.8534820621043127 0.6974850389865661 0.4854992990479367 1.0 0.9818753644696562 2 P60866 1 +Peptidyl-tRNA hydrolase II domain superfamily [IPR023476] 0.8504672897196184 0.6882275024674209 0.4913095273416425 1.0 0.9862971760698424 2 Q6GMV3 1 +Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028] 0.4832822315523036 0.6829499600947179 0.4946384629232443 1.0 0.9862971760698424 6 Q10567,O95782 2 +TBP domain superfamily [IPR012295] 0.4832822315523036 0.6829499600947179 0.4946384629232443 1.0 0.9862971760698424 6 Q10567,O95782 2 +Galactose mutarotase-like domain superfamily [IPR011013] 0.4996217570974912 0.6698410468104793 0.502959124155621 1.0 0.996883054464135 5 Q96C23 1 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.5728033163321575 0.5876172206744491 0.5567892495820479 1.0 1.0 3 O60884 1 +Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080] 0.3939036273231787 0.5683744665092858 0.5697807243921051 1.0 1.0 10 Q5T160,Q15031 2 +S15/NS1, RNA-binding [IPR009068] 0.4498991067957312 0.5483437559457773 0.5834558880652083 1.0 1.0 6 P62277 1 +Nop domain superfamily [IPR036070] 0.5563910279526663 0.5324458111227797 0.5944172635612082 1.0 1.0 3 O00567 1 +Nop, C-terminal domain [IPR042239] 0.5563910279526663 0.5324458111227797 0.5944172635612082 1.0 1.0 3 O00567 1 +Creatinase/aminopeptidase-like [IPR036005] 0.4177732284411745 0.4760797138174144 0.6340175887912951 1.0 1.0 7 Q9Y5B9,Q9NQH7,Q9NQW7 3 +Tautomerase/MIF superfamily [IPR014347] 0.7732891166716769 0.4657894680431617 0.6413662044789676 1.0 1.0 2 P14174 1 +6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927] 0.40008156968892 0.4623059571629909 0.6438619282348568 1.0 1.0 8 P32322,P40939,Q49A26 3 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.3925870025863858 0.4616218034896199 0.6443525560761598 1.0 1.0 132 Q9NW64,Q96T37,Q8IXT5,Q9ULW3,Q86V81,P62750,Q9UKA9,Q15233,Q9H501,Q9BY77,Q8WXA9,P09012,P31483,Q13247,A0AV96,Q15056,P08621,Q13595,Q9UN86,P52272,Q9Y6M1,Q5T8P6,Q01085,Q92879,Q9BTD8,P33240,P42696,Q14151,Q13148,Q9Y4C8,Q9UNP9,Q9NWH9,Q9BYG3,Q9P2N5,Q8IY67,P08579,O43347,Q15427,Q8TBF4,Q8NFH5,Q9NW13 41 +Pyridoxal phosphate-dependent transferase, small domain [IPR015422] 0.3709170247294475 0.4397667674590498 0.6601060392651852 1.0 1.0 14 Q8TD30 1 +R3H domain superfamily [IPR036867] 0.5272802599661627 0.4393720913292239 0.6603919453850116 1.0 1.0 3 O15226 1 +Pyridoxal phosphate-dependent transferase [IPR015424] 0.3695350004704846 0.4293304848876695 0.6676827347702345 1.0 1.0 15 Q8TD30 1 +Pyridoxal phosphate-dependent transferase, major domain [IPR015421] 0.3695350004704846 0.4293304848876695 0.6676827347702345 1.0 1.0 15 Q8TD30 1 +DNA topoisomerase, type IIA-like domain superfamily [IPR013760] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 1.0 2 Q02880 1 +DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 1.0 2 Q02880 1 +DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 1.0 2 Q02880 1 +DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758] 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 1.0 2 Q02880 1 +ISWI, HAND domain superfamily [IPR036306] 0.7579137775097999 0.4255268117656828 0.6704526805360176 1.0 1.0 2 O60264 1 +Arp2/3 complex subunit 2/4 [IPR034666] 0.7567078685559137 0.4224358449722548 0.6727069188908938 1.0 1.0 2 O15144 1 +Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098] 0.4639685679905929 0.4034530349404605 0.6866149781161701 1.0 1.0 4 O75695 1 +Ribosomal protein S5 domain 2-type fold [IPR020568] 0.3624610113050975 0.4024041290307398 0.6873866317565751 1.0 1.0 24 Q8TCS8,Q02880,Q5RKV6,Q96RP9,P82675,Q03426,Q06265 7 +NTF2-like domain superfamily [IPR032710] 0.4095815982603783 0.3987303948405568 0.6900918693540858 1.0 1.0 6 Q9UBU9,Q13555,Q9UN86 3 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.4239038139609042 0.388548024605506 0.6976105216020476 1.0 1.0 5 Q9UBF8 1 +Dbl homology (DH) domain superfamily [IPR035899] 0.4229815303432686 0.3854710963904575 0.6998884168472517 1.0 1.0 5 O75962,Q9H8V3 2 +HSP40/DnaJ peptide-binding [IPR008971] 0.4214258385026777 0.3803042949639119 0.7037195477015232 1.0 1.0 5 P31689,O60884 2 +Kinesin motor domain superfamily [IPR036961] 0.3561556029511035 0.3764270308221677 0.7065994535728117 1.0 1.0 24 O95235,O00159,Q92614,O60333,Q9Y496 5 +RNA-binding domain superfamily [IPR035979] 0.3790400629914434 0.3694504420969512 0.7117920057579081 1.0 1.0 134 Q9NW64,Q96T37,Q8IXT5,Q9ULW3,Q86V81,Q9UKA9,Q15233,Q9BY77,Q8WXA9,P09012,P31483,Q13247,A0AV96,Q15056,P08621,Q13595,Q9UN86,P52272,Q9Y6M1,Q5T8P6,Q01085,Q92879,Q9BTD8,Q9BQ39,P42696,P33240,Q9NR30,Q13148,Q14151,Q9Y4C8,Q9UNP9,Q9NWH9,Q9BYG3,Q9P2N5,Q8IY67,P08579,O43347,Q15427,Q8TBF4,Q8NFH5,Q9NW13 41 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.4967983560527889 0.3497730636256323 0.7265090157788934 1.0 1.0 3 Q9BYT8 1 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.4053947582085186 0.3288402594073392 0.7422764311912196 1.0 1.0 5 O15439 1 +Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047] 0.3306829620055772 0.3179880634492841 0.7504939913355801 1.0 1.0 10 Q9Y4L1,P38646,P17066 3 +Heat shock protein 70kD, C-terminal domain superfamily [IPR029048] 0.343463816930284 0.3108884072359572 0.7558854577776328 1.0 1.0 9 Q9Y4L1,P38646,P17066 3 +Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796] 0.7069641242086224 0.3042761104582486 0.7609175439223064 1.0 1.0 2 P30050 1 +Ribosomal protein L11, C-terminal domain superfamily [IPR036769] 0.7069641242086224 0.3042761104582486 0.7609175439223064 1.0 1.0 2 P30050 1 +Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919] 0.7048537835393303 0.299694732934985 0.7644100165591479 1.0 1.0 2 Q6DKI1 1 +GroEL-like apical domain superfamily [IPR027409] 0.3350453172205451 0.2841671387069553 0.7762822973268002 1.0 1.0 9 Q99832,P48643,P40227,P10809,P78371,P50990,P49368,P17987 8 +GroEL-like equatorial domain superfamily [IPR027413] 0.3350453172205451 0.2841671387069553 0.7762822973268002 1.0 1.0 9 Q99832,P48643,P40227,P10809,P78371,P50990,P49368,P17987 8 +TCP-1-like chaperonin intermediate domain superfamily [IPR027410] 0.3350453172205451 0.2841671387069553 0.7762822973268002 1.0 1.0 9 Q99832,P48643,P40227,P10809,P78371,P50990,P49368,P17987 8 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.3841286505159012 0.265998900319743 0.7902400559420331 1.0 1.0 5 Q9BYT8,P78536 2 +PDZ superfamily [IPR036034] 0.321165515560594 0.2629238166683406 0.7926092989078974 1.0 1.0 27 Q92614 1 +DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921] 0.3808851701125172 0.2570005182268133 0.7971783730192115 1.0 1.0 5 P35251,P35249,P40937 3 +Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014] 0.683147422369612 0.2547742646796959 0.7988974532955511 1.0 1.0 2 P11177 1 +CH domain superfamily [IPR036872] 0.3144983003335077 0.2527197993120729 0.8004847467835889 1.0 1.0 29 O15020 1 +Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101] 0.6816400361772653 0.2518070587571644 0.8011902009962037 1.0 1.0 2 P61011 1 +SRP/SRP receptor, N-terminal [IPR036225] 0.6816400361772653 0.2518070587571644 0.8011902009962037 1.0 1.0 2 P61011 1 +Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222] 0.6795296955079795 0.247686832025627 0.8043767209876216 1.0 1.0 2 P40123 1 +Ribosomal protein L37ae/L37e [IPR011331] 0.6783237865541052 0.245350211180874 0.8061852766410311 1.0 1.0 2 P61513 1 +Dynein light chain superfamily [IPR037177] 0.6777208320771738 0.2441867662052574 0.8070861759326093 1.0 1.0 2 Q96FJ2 1 +Thioredoxin-like superfamily [IPR036249] 0.2323453386231977 0.237925246609526 0.8119390737378165 1.0 1.0 54 Q96JJ7,O14530,P30048,Q13162,P19404,O75880,Q9Y320,O43819,O43396,O15217,Q8N983,Q8NBF2,Q9Y2Q3,Q8IXB1,Q8TB36,P13667,O75368 17 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.3096435610476395 0.2170519283605767 0.8281678764511828 1.0 1.0 19 O15217,O43324,Q5HYI7 3 +ATPase, nucleotide binding domain [IPR043129] 0.3069657799063764 0.2102138521678445 0.8335007686411624 1.0 1.0 23 Q9GZN1,P17066,P61160,Q9NPF4 4 +Rossmann-like alpha/beta/alpha sandwich fold [IPR014729] 0.3037272391826761 0.2053541991210342 0.8372954014552763 1.0 1.0 25 Q5T160,Q9UGM6 2 +F-actin capping protein, alpha subunit, domain 1 [IPR042489] 0.655712993668977 0.2039710621340179 0.8383761125799212 1.0 1.0 2 P52907 1 +Inosine triphosphate pyrophosphatase-like [IPR029001] 0.6475731082303208 0.1902220264204283 0.8491351516469476 1.0 1.0 2 Q96M27 1 +50S ribosomal protein L10, insertion domain superfamily [IPR043164] 0.6457642447995171 0.1872501062969618 0.8514645403902192 1.0 1.0 2 P05388 1 +HECT, E3 ligase catalytic domain [IPR035983] 0.3244124684535626 0.1825633366795031 0.8551406538895774 1.0 1.0 7 Q05086 1 +NET domain superfamily [IPR038336] 0.6418450406994246 0.1809153167512252 0.8564340462071607 1.0 1.0 2 P25440 1 +RNA-binding S4 domain superfamily [IPR036986] 0.3755213194402598 0.1701497528045984 0.8648923668489354 1.0 1.0 4 P62701 1 +RuvA domain 2-like [IPR010994] 0.4200844390832384 0.1698010611892892 0.8651665923407494 1.0 1.0 3 Q7KZ85,Q14807 2 +BRCT domain superfamily [IPR036420] 0.2839243153015139 0.1664322155768183 0.8678168231213963 1.0 1.0 15 O00541,P18887,P09874,O60934,Q9H8V3,Q14676,P35251 7 +P-loop containing nucleoside triphosphate hydrolase [IPR027417] 0.2549142962941503 0.1623346910152124 0.8710422974973122 1.0 1.0 303 Q92614,Q15286,O15439,P61006,Q96P47,Q969Y2,Q9NY93,Q68CQ4,Q8N3C0,Q8WVC6,Q6PL18,Q9H0A0,Q9NVP1,Q15382,Q9Y496,P20338,O00159,O95140,Q9NP72,Q13823,P49750,Q8NHQ9,Q9BQ75,Q8TDD1,O75616,P60953,P51153,Q9H078,Q7Z478,Q9BUJ2,Q9H6R0,Q96SB8,Q9BQ39,O95235,Q9Y6V7,Q9HCN4,Q03518,P51148,Q92620,Q2NKX8,Q9H0S4,P20339,Q9BZE4,Q9BZG1,P35251,Q92930,Q9NVJ2,P46100,P54132,Q96GQ7,Q96RP9,P62330,O60333,Q86XP3,P61019,Q14527,P62820,Q9NUL7,Q9UIJ7 59 +Peptidase M41-like [IPR037219] 0.62827856496834 0.1600923662170392 0.8728083144937433 1.0 1.0 2 Q9Y4W6 1 +Nucleotidyltransferase superfamily [IPR043519] 0.313647278678655 0.15849569914743 0.8740662094126685 1.0 1.0 7 Q96KR1,Q12905 2 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 1.0 3 P10321 1 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 1.0 3 P10321 1 +Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008] 0.3132475466776566 0.1317619919710124 0.8951725503874497 1.0 1.0 6 P41252,Q15031,Q5ST30 3 +WD40-repeat-containing domain superfamily [IPR036322] 0.2383700424424011 0.1240654096835902 0.9012634855904158 1.0 1.0 92 Q14137,Q9BSC4,Q9UMS4,Q8WUA4,Q86W42,O15143,Q13610,Q13347,Q9BUR4,Q12788,Q96BP3,Q5MNZ6,Q9NW82,Q9BY44,O15213,Q6UXN9,Q8TAF3,P61962,O75083,P78406,Q96DI7,Q8N122,Q9BZK7,P50748 24 +Ribonuclease III, endonuclease domain superfamily [IPR036389] 0.5966234549291481 0.1181448539106498 0.9059528840162387 1.0 1.0 2 Q9UPY3 1 +Phosphofructokinase superfamily [IPR035966] 0.3869119420989164 0.1152969081675203 0.9082097889458172 1.0 1.0 3 P08237,P17858 2 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.2276299462947398 0.1147893426387815 0.9086120965576884 1.0 1.0 38 Q9NXH9,P22087,Q86VU5,Q8TEA1,Q9UNQ2,O43709,Q8IY81,P22061 8 +Ribosomal protein L10e/L16 superfamily [IPR036920] 0.5884835694904902 0.1088349932859681 0.9133333680358922 1.0 1.0 2 Q9NX20 1 +Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866] 0.3000014396268052 0.1075866941570839 0.9143235522460182 1.0 1.0 6 Q16775 1 +WD40/YVTN repeat-like-containing domain superfamily [IPR015943] 0.1805431891185761 0.1063515035816699 0.9153034693101916 1.0 1.0 101 Q14137,Q9BSC4,Q9UMS4,Q8WUA4,Q86W42,O15143,Q13610,Q13347,Q9BUR4,Q12788,Q96BP3,Q5MNZ6,Q9NW82,Q15291,Q9BY44,O15213,Q6UXN9,Q8TAF3,P61962,O75083,P78406,Q96DI7,Q8N122,Q9BZK7,Q9HCU5 25 +Citrate synthase superfamily [IPR036969] 0.5619535725052663 0.0825032099014187 0.9342465659065272 1.0 1.0 2 O75390 1 +Citrate synthase-like, small alpha subdomain [IPR016143] 0.5619535725052663 0.0825032099014187 0.9342465659065272 1.0 1.0 2 O75390 1 +Chaperone J-domain superfamily [IPR036869] 0.2139912543344636 0.0822712107174679 0.9344310473116432 1.0 1.0 17 Q8WXX5,O60884,P31689,Q9NZJ4,P25685,Q8IXB1 6 +K Homology domain, type 1 superfamily [IPR036612] 0.1812939337553048 0.078615615927244 0.9373383662690946 1.0 1.0 28 Q8N9N2,Q8TCS8,Q13868 3 +Translation protein, beta-barrel domain superfamily [IPR009000] 0.1804858384514928 0.0728030725548707 0.9419628259023508 1.0 1.0 19 P39023,P09001,P18077,Q5JTZ9,Q96RP9,P49411 6 +SNase-like, OB-fold superfamily [IPR035437] 0.3113122171945723 0.0714992675662215 0.9430004074653412 1.0 1.0 4 Q7KZF4,Q8NHU6,Q92667 3 +eRF1, domain 2 superfamily [IPR042226] 0.5369309617123795 0.0629423108591969 0.9498124424263616 1.0 1.0 2 Q9BRX2 1 +XPC-binding domain superfamily [IPR036353] 0.4895990352728242 0.0379033182118813 0.9697647674014198 1.0 1.0 2 P54725 1 +Signal recognition particle, SRP9/SRP14 subunit [IPR009018] 0.4883931263189481 0.0374396834309685 0.9701344320352704 1.0 1.0 2 P37108 1 +SNARE [IPR010989] 0.2242832111259353 0.0255004777203104 0.9796557674465732 1.0 1.0 5 O15400,Q86Y82 2 +Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035] 0.3846849562857976 0.0180835434473894 0.985572206232738 1.0 1.0 2 P07814 1 +Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056] 0.3846849562857976 0.0180835434473894 0.985572206232738 1.0 1.0 2 P07814 1 +Ubiquitin activating enzyme, alpha domain superfamily [IPR023318] 0.3810672294241778 0.0178767721435581 0.9857371591977347 1.0 1.0 2 Q9UBT2 1 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..dae67c315a3e9d612a0ceb17883e5f286d1b20ca --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Disintegrin domain superfamily [IPR036436]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-glutamyltranspeptidase, large subunit, C-terminal domain [IPR043138]", "Gamma-glutamyltranspeptidase, small subunit [IPR043137]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LOTUS-like domain [IPR041966]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTERF superfamily, mitochondrial/chloroplastic [IPR038538]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "Mir domain superfamily [IPR036300]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mog1/PsbP, alpha/beta/alpha sandwich [IPR016123]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phospholipase C-beta, C-terminal domain superfamily [IPR042531]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Receptor L-domain superfamily [IPR036941]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCAN domain superfamily [IPR038269]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKA1 microtubule binding domain [IPR042031]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOCS box-like domain superfamily [IPR036036]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBCC, N-terminal domain superfamily [IPR038397]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WIBG, N-terminal domain superfamily [IPR036348]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "Wiscott-Aldrich syndrome protein, C-terminal [IPR011026]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "mRNA decapping protein 2, Box A domain superfamily [IPR036189]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "tRNAHis guanylyltransferase Thg1 superfamily [IPR038469]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP13", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATRX", "ATXN10", "ATXN2", "B4GALT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCL2L12", "BCL2L13", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDKAL1", "CDKN2A", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHP1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLPH3", "GOLPH3L", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS14", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LACTB", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED16", "MED21", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL55", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCL", "NCOA5", "NCOR1", "NDC80", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFE", "NENF", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KB", "PICALM", "PIGG", "PIGL", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIP4K2B", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYM1", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMS", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX12", "STX4", "STX6", "STX7", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCP1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "TGS1", "THG1L", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM63A", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPMT", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASL", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WRAP73", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF24", "ZNF281", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2"], "leading_proteins": ["AARS2", "ABCC4", "ABT1", "ACBD3", "ACTR2", "ACTR6", "ADAM17", "AFG3L2", "AGAP3", "AK3", "AKAP1", "ALCAM", "ALG5", "ALYREF", "AP1B1", "AP1M1", "AP2A1", "AP2S1", "ARF6", "ARHGAP1", "ARL8B", "ARPC1B", "ARPC2", "ASCC1", "ASCC3", "ATAD2", "ATRX", "ATXN2", "BLM", "BOP1", "BRD2", "BSG", "BUD23", "CADM1", "CALR", "CAMK2G", "CAP2", "CAPZA1", "CAPZB", "CCT2", "CCT3", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC42", "CELF1", "CEP170", "CHD4", "CIZ1", "CLGN", "CLPB", "CMAS", "CMSS1", "COLGALT1", "COMTD1", "CS", "CSTF2", "CXorf57", "DCAF7", "DCAKD", "DDX18", "DDX21", "DDX27", "DDX28", "DDX42", "DDX47", "DDX49", "DDX50", "DDX54", "DDX55", "DDX56", "DHX29", "DHX33", "DHX38", "DICER1", "DIEXF", "DIMT1", "DIS3", "DLAT", "DLST", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC10", "DNAJC9", "DVL2", "DYNLL2", "ECT2", "EEF1E1", "EIF2A", "EIF2B4", "EIF3I", "EIF4H", "EPB41L2", "EPB41L5", "EPN1", "EPRS", "ERAL1", "ERCC6L", "ESF1", "EXOSC2", "EXOSC6", "EXOSC9", "EXTL3", "F11R", "FBL", "FTSJ3", "G3BP2", "GALM", "GBE1", "GDAP1", "GDAP2", "GFM1", "GGA1", "GLYR1", "GNL2", "GPN1", "GPT2", "GSTA4", "GSTK1", "GTF2F2", "GTF3C2", "GTPBP3", "GTPBP4", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HAGH", "HIST1H1C", "HIST1H1E", "HLA-A", "HLA-C", "HLTF", "HNRNPM", "HNRNPUL1", "HP1BP3", "HSDL2", "HSPA6", "HSPA9", "HSPD1", "HYOU1", "IARS", "IGF2BP2", "ILF2", "ILVBL", "IQGAP2", "KARS", "KDELC2", "KIF1B", "KIF20A", "KIF22", "KIF3A", "KNTC1", "LARS2", "LSM6", "LYAR", "MANF", "MCCC1", "MCL1", "MCM5", "MDC1", "MFN2", "MIF", "MKI67", "MOSPD2", "MRPL16", "MRPL19", "MRPL2", "MRPL3", "MRPL43", "MRPS5", "MRTO4", "MSI1", "MTA1", "MTA2", "MTX3", "MVK", "MYO18A", "MYO1C", "NADK2", "NAT10", "NBN", "NDUFV2", "NHLRC2", "NIFK", "NKRF", "NLN", "NOL10", "NONO", "NOP56", "NSUN6", "NUP35", "NXF1", "OGDH", "OSGEP", "PARP1", "PC", "PCCA", "PCMT1", "PDHA1", "PDHB", "PDIA4", "PELO", "PES1", "PFKL", "PFKM", "PGM3", "PHF3", "PI4KB", "PLOD3", "PNPT1", "POLDIP3", "POLR2A", "POLR2G", "PPIC", "PPIE", "PPIF", "PPIL1", "PPIL3", "PPP1R10", "PPP1R8", "PPWD1", "PRDX3", "PRDX4", "PREB", "PRPF19", "PRRC1", "PTBP2", "PTK7", "PTPRF", "PTRHD1", "PWP1", "PYCR1", "RAB13", "RAB18", "RAB1A", "RAB2A", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5C", "RAB8A", "RAB8B", "RAD23A", "RAE1", "RARS2", "RAVER1", "RBBP5", "RBM12B", "RBM15", "RBM19", "RBM22", "RBM26", "RBM27", "RBM28", "RBM34", "RBM42", "RBM47", "RFC1", "RFC4", "RFC5", "RHEB", "RP2", "RPL12", "RPL14", "RPL15", "RPL23A", "RPL27", "RPL3", "RPL35A", "RPL36A", "RPL37A", "RPL6", "RPL7L1", "RPL8", "RPLP0", "RPS11", "RPS13", "RPS20", "RPS23", "RPS24", "RPS28", "RPS4X", "RPTOR", "RSL1D1", "RSL24D1", "SACS", "SAFB2", "SCO1", "SCO2", "SCP2", "SEC22B", "SF3A2", "SF3B4", "SH3BGRL", "SLTM", "SMAP2", "SMARCA1", "SMARCA5", "SMARCAD1", "SMC2", "SMC6", "SMCHD1", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SPHK2", "SPTBN2", "SRCAP", "SREK1", "SRP14", "SRP54", "SRPRA", "SRSF6", "STX12", "STX7", "SUCLA2", "SUPT16H", "SUPT6H", "TAP1", "TARDBP", "TBL1XR1", "TBL3", "TCP1", "TDRD7", "THOC6", "THYN1", "TIA1", "TIAL1", "TIMM8A", "TIMM8B", "TMX2", "TMX3", "TOP2B", "TRA2A", "TRAPPC4", "TRIO", "TRMT1", "TTF2", "TUFM", "TXNDC9", "TXNL1", "UBA2", "UBE3A", "VAMP7", "VAPA", "VARS2", "WARS2", "WDR1", "WDR45B", "WDR46", "WDR48", "WDR70", "WDR82", "WRAP53", "XPNPEP1", "XPNPEP3", "XRCC1", "YBX3", "YKT6", "YLPM1", "ZC3H15", "ZCCHC3", "ZCRB1", "ZFR", "ZNF512B", "ZNF622"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c6ebc03e0bf181790082a149b4981363b399390a --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5af7d32d94eab7c143b75605125eb17e71dc383ed86792776b32f199371660b +size 73098 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d943cbe2fe25598ee1ddea0297e361238b1639d5 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.5 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e780318a649416377286a3e4f8f761b9bbc041a8 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..911c0f98110fcfc0055bf4e7c9370c039a6363c6 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..28a99d0600a316b9686b0361c9ecf2cfa344e679 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "EIF5A", "FASN", "LDLR", "LRP1", "SLIT2"], "leading_proteins": []} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..91419d149c90380e84c9d43ad89e1e73ee130429 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "G-protein beta WD-40 repeat [IPR020472]", "1": "WD40 repeat [IPR001680]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..96ab2d6aaf3b96bf5f5f395728fbb2b5d6c64c26 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:894bd80694b45d4220249f6cadadcb84917efd2f9a6be055106be9c339ab1203 +size 151776 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5ba9c703fbc600fbfc8ecc03dbbfb584d7be6fbc --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a08e840607df062cfa95dd66144a5b0fe1184a0059b2993dc6159a136b4bade3 +size 145984 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e29daac27fd9034c02334f8b9f81a901025dce22 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14fb4c64b6e436eb1cd9be7aea7b3476a3801420a42b2b39b87e784dc2a6a179 +size 78237 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b085f404303875ad0a1de0d8c374a905a38d1e5d --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 81, + "title": "Average number of proteins per term", + "value": 5.604938271604938 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4f0de947f91456cdde3874d1e23de10f5bb5e73b --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..372b0e0aca851f318cad133481a3c763a7fc5dd3 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Filamin/ABP280 repeat [IPR001298] 0.6676553900948599 1.1793826065440858 0.2382458579394542 0.9999999997326988 0.6225133707450254 4 Q7Z4H8 1 +Pentatricopeptide repeat [IPR002885] 0.617996904292105 0.976896591140494 0.3286203495906707 0.9999999999999905 0.7050794935634281 4 Q96EY7 1 +Spectrin repeat [IPR002017] 0.4376867252428765 0.7576360407346514 0.4486688980475937 1.0 0.7050794935634281 12 O15020 1 +Spectrin/alpha-actinin [IPR018159] 0.4135775282923539 0.6286322493193781 0.5295898423151288 1.0 0.7396464317503145 14 O15020 1 +G-protein beta WD-40 repeat [IPR020472] 0.3176128554748302 0.3270386953892949 0.7436386182816603 1.0 0.9485649928164536 35 O75083,Q12788,Q96DI7,Q13610,Q9BZK7,Q8TAF3 6 +Filamin/ABP280 repeat-like [IPR017868] 0.3574322993533285 0.1968904330358235 0.8439132804732248 1.0 0.9815826230175844 5 Q7Z4H8 1 +WD40 repeat [IPR001680] 0.2061022106055333 0.107307717608609 0.9145448621314244 1.0 0.9815826230175844 89 Q14137,Q9BSC4,Q9UMS4,Q8WUA4,Q86W42,O15143,Q13610,Q13347,Q9BUR4,Q12788,Q96BP3,Q5MNZ6,Q9NW82,Q15291,O15213,Q6UXN9,Q8TAF3,P61962,O75083,P78406,Q96DI7,Q8N122,Q9BZK7,Q9HCU5 24 +Proteasome/cyclosome repeat [IPR002015] 0.412119384986424 0.0203206271272932 0.9837876011155808 1.0 1.0 2 Q99460 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..77a6184a8ededceee617713346da3edfa2b74555 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "Furin-like repeat [IPR006212]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN2", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "APC", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ARVCF", "ASB6", "ASPH", "BCOR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DTL", "DYNC1I2", "EDC4", "EGFR", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GPSM1", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC4", "HTT", "HUWE1", "IFIT5", "IFT88", "IGF1R", "IGF2R", "ILK", "IPO4", "IPO5", "JUP", "KAT7", "KDELC2", "KDM2A", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LARP1", "LASP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "MACF1", "MAP1B", "MAP4", "MED16", "MKI67", "MKLN1", "MRPS27", "MTCH1", "MTCH2", "MYCBP2", "NAA15", "NAA16", "NASP", "NEK9", "NFKB1", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PGGT1B", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "POLR2A", "PPID", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF39", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABEPK", "RABGGTA", "RABGGTB", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RAP1GDS1", "RBBP5", "RBBP7", "RCC1", "RCC2", "RPAP3", "RPTOR", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SETD7", "SGTA", "SHCBP1", "SHOC2", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE1", "SYNE2", "TAGLN2", "TBL1XR1", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TRIO", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WRAP53", "WRAP73", "XAB2", "XPO1", "YTHDC2"], "leading_proteins": ["ARPC1B", "BOP1", "DCAF7", "EIF3I", "GTF3C2", "KDELC2", "NOL10", "PPWD1", "PREB", "PRPF19", "PSMD1", "PTCD3", "PWP1", "RAE1", "RBBP5", "RPTOR", "SNRNP40", "SPTBN2", "TBL1XR1", "TBL3", "THOC6", "WDR1", "WDR45B", "WDR46", "WDR48", "WDR70", "WDR82", "WRAP53"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..49a1ac0a8aadf427d17542ac4cafd08df501e965 --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Ribosomal large subunit biogenesis", "1": "Ribosome assembly", "2": "Mitochondrial translation", "3": "Mitochondrial gene expression", "4": "Ribosomal small subunit biogenesis", "5": "Rrna transcription", "6": "Maturation of lsu rrna", "7": "Regulation of cell aging", "8": "Nucleolar large rrna transcription by rna polymerase i"} \ No newline at end of file diff --git a/msigdb_gobp/advanced/plot_0.png b/msigdb_gobp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7a5628469dc5cae7308b4a74a1dc0f7ab2633c43 --- /dev/null +++ b/msigdb_gobp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version 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sha256:27bb86ea25d00cc7c97d152de4af92538985fecb090d0eb3c368bae493447d72 +size 194567 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f8a38d7b405b72cefb0de5219f0292d6826c43ff --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,47 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Ribosomal large subunit biogenesis 32 59 3.8494941513854894 0.0001183620096203 27.936893203883496 57.978155339805824 -1.4029915310497645 0.3151876370658045 9.730639132175924 2.8671234011163116 1.5412102637359888 0.3569411110995745 0.0048225524960019 0.0048690104254232 0.0002965658497824 9.283901202019492e-15 +Ribosome assembly 23 50 3.2929298710419586 0.0009914920185529 19.055825242718445 47.779126213592235 -0.7035456798868047 0.4889990460878361 7.9427129727517 2.4439843351936754 1.0202647585816325 0.348323682133052 0.0327224420542492 0.0191373699896123 0.0028506301979692 1.275964533331594e-09 +Mitochondrial translation 17 49 3.077205388753799 0.0020895127358606 11.949029126213592 42.29126213592233 -0.1659271391700248 0.6275290115007198 8.747528029690423 4.919016138033724 0.9455427757975456 0.3325795728137262 0.0056332205677222 0.0059312171066033 0.0004352442147906 5.431729317630697e-05 +Mitochondrial gene expression 21 64 2.8493420704178813 0.0043809749863261 16.449029126213592 56.182038834951456 -0.2404951074706974 0.6120234675741325 10.427271191174482 6.788294302140445 1.0133100522202234 0.3376694104983603 0.0146537708834138 0.0195932975716513 9.38103003069487e-06 2.989464532339885e-06 +Ribosomal small subunit biogenesis 19 54 2.8001827509276267 0.0051073682887134 23.733009708737864 53.97572815533981 -1.1372450493015922 0.3808999194200835 8.485085582916668 3.272330781206946 1.1326078966579582 0.3577333752424699 0.0472622034410549 0.0051214743942411 0.001712275077341 1.3306335778007705e-06 +Nucleotide transmembrane transport 4 9 2.4151665310973947 0.0157280169137883 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 0.0756950383436983 0.1459927402947744 0.000508984722673 7.091157508407514e-05 +Trna wobble base modification 0 5 2.407416641619855 0.0160658294109254 2.093827160493827 4.958024691358025 -0.2915722765082824 0.532136186935365 1.5091773312106451 1.7315421084872324 0.946642475160002 0.3180719233093079 0.0756950383436983 0.1459927402947744 0.3279997416386323 0.5529659277501753 +Regulation of transcription of nucleolar large rrna by rna polymerase i 4 11 2.2916742233254124 0.0219244489170691 5.381067961165049 10.189320388349516 -1.0084433603837897 0.3684271391121299 2.0592983123070345 0.7808897864080142 0.8267609135675357 0.3091869365015434 1.0 1.0 0.0509703724436577 0.0005539528919822 +Regulation of fatty acid transport 1 5 2.264542611490709 0.0235407620354315 1.3810679611650485 4.548543689320389 0.6157357570119139 0.4735209512695758 1.030096057940794 0.7883082633044994 0.8644473952298549 0.3082995501275736 1.0 0.004071454093033 0.0236659942035878 0.0832040423996277 +Striated muscle cell apoptotic process 1 5 2.250080632713876 0.024443827265846 2.4223300970873787 5.101941747572815 -0.5860053553552291 0.5099100166068848 1.327925021192725 1.2519096544936548 0.7525599317914898 0.3005820862413204 1.0 0.2108642126213972 0.1162426898263886 0.3306436748543453 +Histone h3 k27 methylation 3 7 2.249656898179548 0.0244707335832763 4.356796116504855 7.691747572815534 -1.379115130968022 0.2197697774511291 1.6812435951975209 1.318144420380235 1.0709765358431076 0.274485257004507 1.0 1.0 0.0779048373986419 0.0123019851581077 +Nucleosome positioning 5 10 2.246175667332205 0.0246927581615898 5.915048543689321 9.186893203883496 -1.4577623895477416 0.2033217018902848 2.116753960133439 0.5715955001389142 1.226441656392813 0.2824784359054791 1.0 0.1203280145079081 0.0034718672031755 1.7243466814835008e-05 +Nucleotide transport 4 11 2.2331528770258986 0.0255388646311061 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 0.1201219647894398 0.2263045436956677 0.003448903470559 0.001340966968491 +Establishment of epithelial cell polarity 2 10 2.23139663810892 0.0256548673564354 3.1407766990291264 8.924757281553399 -0.2159104022826458 0.553084154059003 2.1586555008838024 1.6798834591225031 0.8675571743869503 0.2912314648554543 0.1373006943976843 0.2562935091164666 0.0363308723059728 0.0570843575034502 +Rrna transcription 14 24 2.22829456120667 0.0258608787911311 10.33495145631068 22.15776699029126 -1.0239304134365248 0.3747324095919725 3.982295984519875 1.5206867585242978 0.9658986293874984 0.3198884955326619 1.0 1.0 0.0017240342445666 6.945797851751316e-07 +Type b pancreatic cell development 1 6 2.208611832013077 0.027201651658852 1.4733009708737863 3.701456310679612 -0.0529892878897804 0.542159301272675 1.1111813781051234 1.1949317791527294 1.032788839559643 0.3191892585932279 0.0711332726649859 0.009201700056446 0.0509703724436577 0.1657053101695293 +Enteroendocrine cell differentiation 1 6 2.208611832013077 0.027201651658852 1.7864077669902914 4.490291262135922 -0.137226050158687 0.5619881760340598 1.3681571862009374 1.516063794742647 0.9300585534703136 0.3099776362324148 0.1026081339138497 0.0193632099375005 0.1003847610205272 0.2938977751084773 +Endocrine pancreas development 1 7 2.193241136318416 0.0282900101757432 2.0509708737864076 5.851941747572815 -0.126603332527314 0.527149424927022 1.4497485651188915 1.6220330993069874 0.9029201146380612 0.2859587949302581 0.1330370821365251 0.0325598174288622 0.1582166891915067 0.4195949232255271 +Purine containing compound transmembrane transport 4 7 2.1848300217736383 0.0289013119332601 3.6432038834951457 8.228155339805825 0.8480777288434221 0.3004167480224937 2.0847056152178514 1.431742605530374 1.2278207398320582 0.2967021731271802 0.066549445548378 0.1289666473793992 0.0043393811270145 0.0003847105612191 +Glandular epithelial cell development 1 7 2.1728190479582934 0.0297939391029022 2.0072815533980584 5.247572815533981 -0.0558500384037346 0.5550666489327928 1.4622915213948338 1.4703770509234575 0.8929219066772065 0.2982449953222876 0.0937235599037543 0.0161297090986061 0.0852058322554232 0.2568852822677916 +Glandular epithelial cell differentiation 1 7 2.1728190479582934 0.0297939391029022 2.2257281553398056 5.978155339805825 -0.1240789043074417 0.5673939220190088 1.5903282325562635 1.717134804560956 0.8420426108647117 0.2942042521434682 0.1499686155438198 0.0412914524019695 0.1934880896161839 0.486244277936926 +Negative regulation of signal transduction by p53 class mediator 2 9 2.148429777782352 0.0316796293313341 2.1262135922330097 6.490291262135922 0.0025135391117914 0.5277846023571443 1.4626721898500985 1.409882909350627 0.9389842991964372 0.2948801347666068 0.1157751708195439 0.0246740936940832 0.022497237178051 0.1215640938111839 +Cellular response to vascular endothelial growth factor stimulus 3 6 2.123224262299364 0.0337350637811075 2.2354368932038833 6.213592233009709 -0.2739927244592021 0.4779011439627239 1.510611833031637 1.687478071411025 1.0023419766853818 0.297801109567981 1.0 0.2851312580635185 0.0498893444602038 0.0830818582384505 +Schwann cell differentiation 1 7 2.106364330003176 0.0351727172551072 2.728155339805826 8.487864077669903 0.0772419244875512 0.5793500773339586 1.8138848228668836 2.129849874141248 0.8733832080799478 0.3006049084677616 0.1287528218161406 0.0305060181117638 0.1496006016376268 0.4022434037686819 +Positive regulation of muscle cell apoptotic process 3 7 2.1026545928947384 0.0354959739956228 2.5558252427184467 7.434466019417476 -0.3197631713496143 0.5901235584559514 1.545205566034679 1.4014820367492251 0.7076910578355299 0.2806850041061193 1.0 0.1543818096433915 0.0639524888435202 0.0081630373328644 +Protein localization to phagophore assembly site 3 8 2.086619374442137 0.0369225545343345 1.9684466019417477 5.618932038834951 0.0897566017254424 0.5531333633229247 1.4915537329948203 1.8480981631461024 0.8531235926546605 0.2897965996333904 0.0027067874988798 0.0104494791604543 0.000508984722673 0.0064898601794518 +Maturation of lsu rrna 15 26 2.0820063035884653 0.037341893948763 13.902912621359222 25.089805825242717 -1.3079065801307634 0.2925855633427192 5.026173365603582 0.9971770646271874 1.2736340990008843 0.3404565519165671 0.1287528218161406 0.2414457297612108 0.0303754901318735 3.551822374612823e-08 +Regulation of cell aging 5 12 2.070365633684824 0.038418117544611 2.3980582524271843 11.618932038834952 0.3917787341402564 0.5635158804690975 1.7000274459534483 1.6917649843792049 0.7213180124641434 0.2700905003542821 1.0 0.2921659829416722 0.0101719456814394 0.0065078126490031 +Regulation of organic acid transport 1 10 2.068551906432245 0.038588154969509 3.0266990291262137 9.95873786407767 0.5438090247089712 0.4615742763522461 1.7589620109651245 1.3814816722984091 0.8909245759390145 0.2944812864916606 1.0 0.0246740936940832 0.1243944683174773 0.3488245079892343 +Schwann cell development 1 6 2.0613561121983506 0.0392690786017611 2.4150485436893203 7.487864077669903 0.0164677406559132 0.5754256017702141 1.6880697161478695 2.129849874141248 0.8900651354666074 0.3003336502630982 0.1070183553885475 0.0210734332562196 0.1082353444632946 0.3123234565768453 +Myeloid cell apoptotic process 3 7 2.060856252975401 0.0393167559229423 1.7936893203883495 5.310679611650485 0.084525588305955 0.4575496812250927 1.3159436720993696 1.2130289955121631 1.080649533921299 0.3019823151311963 1.0 0.1951188871774342 0.0158941023821007 0.0206786415510524 +Positive regulation of phagocytosis 1 6 2.051811331342949 0.0401880016465829 2.587378640776699 7.546116504854369 -0.0473463813244279 0.5515569356036101 1.5531477346850735 1.7873094890722172 0.8938207137000734 0.2983693215665957 0.1244478155008913 0.2339121686337894 0.1410845222447507 0.3846499012456358 +Histone h3 k4 trimethylation 4 9 2.0461100007988566 0.0407455492733142 3.75 9.03640776699029 -0.9035828887301264 0.3302171272506756 1.869043938145502 1.1217768104069803 1.142144906815856 0.3073348119719959 1.0 1.0 0.0927037920539492 0.0809536104076691 +Mitochondrial rna processing 3 11 2.0367160672050915 0.0416785034664013 4.878640776699029 9.75485436893204 -0.5754858353442859 0.5001439587425756 2.424556830106263 1.6824625756899965 0.7747452075919211 0.2981731624750237 0.0937235599037543 0.179062604831997 0.012195883686582 0.0147942005316265 +Membrane disassembly 1 5 2.0286175254002257 0.0424972621178696 2.0970873786407767 5.456310679611651 -0.0510829921193445 0.6605562102216185 1.367192311859488 0.7475097691231128 0.6691018194430481 0.2692127402234378 1.0 1.0 1.0 0.1144905971504207 +Nucleolar large rrna transcription by rna polymerase i 5 14 2.02320380831455 0.0430521392113183 6.881067961165049 13.08495145631068 -1.118325226148634 0.3270787085911761 2.491330760165404 0.8095706326775913 0.8978428606771999 0.3041541790889251 1.0 1.0 0.0105546488673461 0.000211792782996 +Purine nucleotide transport 4 9 2.017321147168277 0.0436620101540166 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 0.0937235599037543 0.179062604831997 0.012195883686582 0.0023331236629958 +Regulation of helicase activity 0 9 2.0151788219665026 0.0438859157002746 3.145631067961165 8.33495145631068 -0.2771861439907268 0.6033505410145277 2.1929178460268712 0.7817342852844189 0.7367253148085904 0.2865681477116518 0.0619434524836269 0.1203280145079081 0.2759666252930612 0.4800702486508365 +Establishment of tissue polarity 4 8 2.0147140615773416 0.0439346179913642 3.378640776699029 8.936893203883495 -0.2407835542107216 0.5808664853431775 2.2891322172062987 1.429881541109017 0.8569121627881088 0.3160230002914249 0.2260688267312995 0.4017902994798545 0.3657375888711583 0.2503613805649987 +Negative regulation of cell aging 2 6 1.997256926540193 0.0457972798907433 1.4150485436893203 4.436893203883495 0.4449080488727195 0.4593397992109042 1.033453418648996 1.1399191157868775 0.9851582751260632 0.2986294132747129 1.0 0.1543818096433915 0.0076785979426991 0.0477467344295515 +Ribosomal small subunit assembly 7 14 1.99223170836282 0.0463456407026769 6.213592233009709 13.322815533980584 -0.6715740764729782 0.4696041666418296 3.085042164074007 1.1865605982632863 0.8041941914732428 0.3128768726201692 0.0802348466038066 0.1543818096433915 0.0639524888435202 0.0001050755974966 +Ribosomal large subunit assembly 12 22 1.981358828844035 0.0475510473984259 10.949029126213592 22.00242718446602 -0.9337020047554596 0.3779626044413149 4.209884811412927 0.9412313418456992 1.116757197008177 0.339166817285299 0.1157751708195439 0.2186221342412543 0.022497237178051 1.5415586399478142e-06 +Negative regulation of myeloid cell differentiation 1 11 1.9740076056164595 0.0483808781386296 4.820388349514563 12.344660194174756 -0.6804140792803948 0.4869080520510317 2.417928955058218 1.5273066690193655 0.7707879441712145 0.3105042745786013 0.2027885470531376 0.3651666660190783 0.3118225611820906 0.6669329198655273 +Positive regulation of peptide secretion 3 13 1.971810339747152 0.0486312615533086 4.563106796116505 11.859223300970871 -0.3731861445402221 0.6077811692166766 2.7840387750920335 2.1223698465796805 0.6953948882690625 0.2905444754169244 1.0 0.3128615540599918 0.0655524699240303 0.1138845343006641 +Muscle cell apoptotic process 4 13 1.9682422602611536 0.049040169939043 2.679611650485437 12.66019417475728 0.0978583218707787 0.6800327557957822 2.0958284606721262 2.111243125533319 0.5884707229681105 0.2412010437606453 1.0 0.3460310778663031 0.0878701351278624 0.0578279985029231 +Mrna 3 splice site recognition 2 6 1.9679009620587475 0.0490794341058542 2.3398058252427183 4.531553398058253 -0.3162313299737057 0.5329425221171521 1.27182613193352 0.6693530527939419 0.8885580241084122 0.3057391536735709 0.0003491251705821 0.0013923625346842 0.0002757976371321 0.0020977388537863 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..257194c419ba7a3442d757135bcd3f05e4e18a8f --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 6491, + "title": "Average number of proteins per term", + "value": 20.309351409644123 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..802e77067164da1fc7bc45d5da9000f6a74e89f9 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f8a6e5250e983e38025e8517258ad283f606b28d --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1827 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosomal large subunit biogenesis 0.6239608857403427 3.8494941513854894 0.0001183620096203 0.536214573256287 0.7682878044456531 59 Q14137,P83731,O00541,Q02878,P62424,P18077,P62750,P50914,P55769,Q9UHA3,Q9BYD6,Q9NVP1,Q9NYY8,Q9NVU7,Q9Y4W2,P46087,Q8TDN6,Q9NZM5,O76021,P63173,O95478,Q9BYG3,Q99848,Q9BZE4,Q9H7B2,P39023,Q6DKI1,Q969S3,Q9H9Y2,O75683,Q8IY81,Q9NUL7 32 +Ribosome assembly 0.5437498449606326 3.2929298710419586 0.0009914920185529 0.9984019438786752 0.9840933925754122 50 Q14137,P83731,Q02878,P62750,P62841,P62857,P39019,Q567V2,P82912,Q9Y3A5,Q9NYY8,Q07021,P46087,O75616,Q8TDN6,Q7Z478,Q9NZM5,P63173,Q9BY44,Q9Y2R9,Q9H7B2,P39023,Q9NUL7 23 +Mitochondrial translation 0.5193830592810847 3.077205388753799 0.0020895127358606 0.9999987309183096 0.9840933925754122 49 Q5T160,Q9NYY8,Q07021,Q5T653,Q9BW92,Q15031,Q9BSH4,Q96RP9,P82914,P82912,Q9BRT2,Q96EY7,Q9Y3D3,Q9Y2R9,Q9NP81,Q567V2,Q9UGM6 17 +Mitochondrial gene expression 0.5296676532943781 2.8493420704178813 0.0043809749863261 0.9999999999995804 0.9840933925754122 64 Q5T653,P82914,Q9Y3D3,Q567V2,P82912,Q9UGM6,Q9NYY8,Q7L8L6,Q07021,Q8TCS8,Q96EY7,Q9NP81,Q5T160,Q15031,Q9BSH4,Q9BRT2,Q9Y2R9,Q96RP9,Q969Z0,Q00059,Q9BSK2 21 +Ribosomal small subunit biogenesis 0.5028594212976221 2.8001827509276267 0.0051073682887134 0.9999999999999964 0.9840933925754122 54 Q9BSC4,P62841,P55769,Q2NL82,Q68CQ4,P62857,Q9H0A0,P82912,O75616,P62081,P63173,Q12788,P62847,Q9Y2P8,Q9Y2R9,P62312,Q13895,O75683,Q9H583 19 +Nucleotide transmembrane transport 0.7913097216063374 2.4151665310973947 0.0157280169137883 1.0 0.9840933925754122 9 O15439,Q9BSK2,P41440,Q8TB61 4 +Regulation of transcription of nucleolar large rrna by rna polymerase i 0.7318956637823133 2.2916742233254124 0.0219244489170691 1.0 0.9840933925754122 11 Q9P0M6,Q9NZM5,O75367,Q12824 4 +Regulation of fatty acid transport 0.8756884561869263 2.2645426114907092 0.0235407620354315 1.0 0.9840933925754122 5 P31749 1 +Striated muscle cell apoptotic process 0.8721235143557073 2.250080632713876 0.024443827265846 1.0 0.9840933925754122 5 P17655 1 +Histone h3 k27 methylation 0.8161721067187491 2.249656898179548 0.0244707335832763 1.0 0.9840933925754122 7 P10412,O75367,P16403 3 +Nucleosome positioning 0.7230223995848573 2.2461756673322055 0.0246927581615898 1.0 0.9840933925754122 10 P10412,P16403,P16402,Q92522,P07305 5 +Nucleotide transport 0.7202132036401272 2.2331528770258986 0.0255388646311061 1.0 0.9840933925754122 11 O15439,Q9BSK2,P41440,Q8TB61 4 +Establishment of epithelial cell polarity 0.7200532143167513 2.2313966381089196 0.0256548673564354 1.0 0.9840933925754122 10 P62330,Q92614 2 +Rrna transcription 0.6819624410233018 2.22829456120667 0.0258608787911311 1.0 0.9840933925754122 24 O75367,Q12824,Q9H9Y6,O15446,O15160,Q9P0M6,Q13610,Q9H2V7,Q12789,Q9BYG3,Q9Y5Q8,Q9Y5Q9,Q9NZM5,Q8WUA4 14 +Type b pancreatic cell development 0.8341767515465093 2.208611832013077 0.027201651658852 1.0 0.9840933925754122 6 Q15382 1 +Enteroendocrine cell differentiation 0.8341767515465093 2.208611832013077 0.027201651658852 1.0 0.9840933925754122 6 Q15382 1 +Negative regulation of transcription by rna polymerase i 0.9210915645884654 2.198926898352892 0.0278831206426173 1.0 0.9840933925754122 4 Q9P0M6,Q9NZM5 2 +Endocrine pancreas development 0.8031399991533001 2.193241136318416 0.0282900101757432 1.0 0.9840933925754122 7 Q15382 1 +Purine containing compound transmembrane transport 0.8012037503272464 2.1848300217736383 0.0289013119332601 1.0 0.9840933925754122 7 O15439,P41440,O43808,Q8TB61 4 +Glandular epithelial cell development 0.798441798344739 2.1728190479582934 0.0297939391029022 1.0 0.9840933925754122 7 Q15382 1 +Glandular epithelial cell differentiation 0.798441798344739 2.1728190479582934 0.0297939391029022 1.0 0.9840933925754122 7 Q15382 1 +Negative regulation of signal transduction by p53 class mediator 0.7346858732029862 2.1484297777823516 0.0316796293313341 1.0 0.9840933925754122 9 Q8N2F6,P14174 2 +Cellular response to vascular endothelial growth factor stimulus 0.8137487699407695 2.123224262299364 0.0337350637811075 1.0 0.9840933925754122 6 P31749,Q16539,P46734 3 +Schwann cell differentiation 0.7832229592362103 2.1063643300031756 0.0351727172551072 1.0 0.9840933925754122 7 P11047 1 +Positive regulation of muscle cell apoptotic process 0.7823764673109947 2.1026545928947384 0.0354959739956228 1.0 0.9840933925754122 7 P04179,P17655,O95140 3 +Protein localization to phagophore assembly site 0.750962188378873 2.0866193744421375 0.0369225545343345 1.0 0.9840933925754122 8 Q9Y4P1,O95140,P53365 3 +Maturation of lsu rrna 0.6464456590326845 2.0820063035884653 0.037341893948763 1.0 0.9840933925754122 26 Q14137,Q9BZE4,P62424,Q6DKI1,Q9Y4W2,P46087,P55769,Q9BYG3,O95478,Q8IY81,Q9H9Y2,Q9BYD6,Q9NVP1,Q9H7B2,O76021 15 +Regulation of type b pancreatic cell development 0.8901806853545597 2.078724866455447 0.0376426460713616 1.0 0.9840933925754122 4 Q15382 1 +Regulation of cell aging 0.6877665989518914 2.070365633684824 0.038418117544611 1.0 0.9840933925754122 12 Q8TCS8,Q15554,Q9NX47,O43324,P14174 5 +Regulation of organic acid transport 0.6876188992248964 2.0685519064322455 0.038588154969509 1.0 0.9840933925754122 10 P31749 1 +Schwann cell development 0.7990630625675954 2.0613561121983506 0.0392690786017611 1.0 0.9840933925754122 6 P11047 1 +Myeloid cell apoptotic process 0.7728608832396391 2.060856252975401 0.0393167559229423 1.0 0.9840933925754122 7 P62330,P14174,P78536 3 +Negative regulation of notch signaling pathway 0.9611677594914164 2.058430303174881 0.0395488453184542 1.0 0.9840933925754122 3 Q9Y5A9 1 +Positive regulation of phagocytosis 0.7968058058806391 2.051811331342949 0.0401880016465829 1.0 0.9840933925754122 6 Q92614 1 +Histone h3 k4 trimethylation 0.7133671336199406 2.0461100007988566 0.0407455492733142 1.0 0.9840933925754122 9 P10412,Q6UXN9,P16403,P16402 4 +Mitochondrial rna processing 0.6814767810690558 2.0367160672050915 0.0416785034664013 1.0 0.9840933925754122 11 Q969Z0,Q9NYY8,Q7L8L6 3 +Membrane disassembly 0.8182072771386691 2.0286175254002257 0.0424972621178696 1.0 0.9840933925754122 5 Q99986 1 +Nucleolar large rrna transcription by rna polymerase i 0.6770662863992085 2.02320380831455 0.0430521392113183 1.0 0.9840933925754122 14 O75367,Q12824,O15160,Q9P0M6,Q9NZM5 5 +Lipid export from cell 0.8748453324047731 2.01855444810104 0.0435335495975848 1.0 0.9840933925754122 4 P14174,P82094 2 +Purine nucleotide transport 0.7074059594109791 2.017321147168277 0.0436620101540166 1.0 0.9840933925754122 9 O15439,P41440,O43808,Q8TB61 4 +Establishment of tissue polarity 0.7353366070368659 2.0147140615773416 0.0439346179913642 1.0 0.9840933925754122 8 P60953,O75083,O14641,Q13308 4 +Negative regulation of cell aging 0.7839461682237705 1.997256926540193 0.0457972798907433 1.0 0.9840933925754122 6 Q9NX47,P14174 2 +Ribosomal small subunit assembly 0.6711925713444892 1.99223170836282 0.0463456407026769 1.0 0.9840933925754122 14 P63173,P62841,O75616,P62857,Q9Y2R9,P39019,P82912 7 +Regulation of mitochondrial mrna stability 0.868129516103155 1.9920946604122811 0.0463606727204068 1.0 0.9840933925754122 4 Q9NYY8,Q7L8L6 2 +Ribosomal large subunit assembly 0.6488069879911159 1.981358828844035 0.0475510473984259 1.0 0.9840933925754122 22 P39023,Q14137,P83731,Q9NYY8,P63173,Q02878,P62750,P46087,Q8TDN6,Q9NZM5,Q9H7B2,Q9NUL7 12 +Negative regulation of myeloid cell differentiation 0.6692553540195416 1.9740076056164593 0.0483808781386296 1.0 0.9840933925754122 11 Q96T37 1 +Positive regulation of peptide secretion 0.6681999058496414 1.971810339747152 0.0486312615533086 1.0 0.9840933925754122 13 Q92930,Q8NE86,P55809 3 +Muscle cell apoptotic process 0.6675188323949336 1.9682422602611536 0.049040169939043 1.0 0.9840933925754122 13 P04179,P17655,O95140,Q96QC0 4 +Mrna 3 splice site recognition 0.7770553284865099 1.967900962058747 0.0490794341058542 1.0 0.9840933925754122 6 Q15428,O95391 2 +Regulation of myoblast fusion 0.8014652174289643 1.95882934137988 0.0501327761519743 1.0 0.9840933925754122 5 P17655,P41440 2 +Positive regulation of myoblast fusion 0.8014652174289643 1.95882934137988 0.0501327761519743 1.0 0.9840933925754122 5 P17655,P41440 2 +Actomyosin structure organization 0.4253772531791899 1.9569210236942656 0.050356754369091 1.0 0.9840933925754122 56 Q9HCM4,Q9Y281,Q92614,P35080,Q9Y5S2,Q9NWH9,Q9Y624,O75122,P60953,Q9Y613 10 +Respiratory electron transport chain 0.4206908285517705 1.9512400527215703 0.0510284964814278 1.0 0.9840933925754122 54 O14548,P20674,P19404,O95139,O75438,O43676,O43819,O14949,O95168,P38117,P04179,O75380,P28331,P08574,P03915,Q16795,Q9UDW1,P14927 18 +Organism emergence from protective structure 0.7990083540203985 1.948548854044999 0.0513493251639323 1.0 0.9840933925754122 5 Q9BZK7 1 +Epithelial cell morphogenesis 0.7465270907751682 1.944275681578561 0.0518622155795371 1.0 0.9840933925754122 7 Q9NWH9,O60568 2 +Defense response to fungus 0.7701296583578843 1.9383114567585171 0.0525852354906892 1.0 0.9840933925754122 6 P81605 1 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.7693158457855954 1.9348289389601676 0.0530112906364292 1.0 0.9840933925754122 6 Q8N2F6 1 +Regulation of megakaryocyte differentiation 0.7654455203717323 1.9182509447662277 0.0550791992987149 1.0 0.9840933925754122 6 Q96T37 1 +Non canonical wnt signaling pathway 0.7911898796406247 1.9157677019542108 0.0553946705422765 1.0 0.9840933925754122 5 P60953,O14641,Q13308 3 +Regulation of establishment of planar polarity 0.7911898796406247 1.9157677019542108 0.0553946705422765 1.0 0.9840933925754122 5 P60953,O14641,Q13308 3 +Translocation of molecules into host 0.7135628728666603 1.9137018052317216 0.0556582682726551 1.0 0.9840933925754122 8 Q86V81 1 +Regulation of rrna processing 0.6858890255145011 1.9127843325588685 0.0557756676983434 1.0 0.9840933925754122 9 Q9H583,Q9Y5A9,O43709,Q9UNQ2 4 +Protein trimerization 0.8476567545863674 1.9110330908912017 0.0560003285334471 1.0 0.9840933925754122 4 Q99720,P14174 2 +Sno s rna metabolic process 0.6561608074555774 1.9065493715811184 0.0565789665319595 1.0 0.9840933925754122 12 Q13868,P22087,Q9BRJ7,Q5RKV6,O60832 5 +U4 snrna 3 end processing 0.7377043961974431 1.9049278917321175 0.0567894450441102 1.0 0.9840933925754122 7 Q5RKV6,Q06265,Q13868 3 +Epithelial cell proliferation involved in lung morphogenesis 0.9191531447349796 1.900681936154438 0.0573436859972811 1.0 0.9840933925754122 3 Q13247 1 +Trna transcription 0.7610722896672523 1.8994875092358428 0.0575004073819844 1.0 0.9840933925754122 6 Q9Y5Q8,P62875,Q9Y5Q9,Q12789 4 +Negative regulation of dna metabolic process 0.4771823082828374 1.8934132712134528 0.0583029319185877 1.0 0.9840933925754122 43 P10412,P16403,P16402,P54132,Q96BK5,Q9BRJ7,Q15554,O60934,Q92522,P07305 10 +Positive regulation of protein tyrosine kinase activity 0.7852970954805949 1.8909954306994812 0.0586249541852192 1.0 0.9840933925754122 5 O14641 1 +Myoblast fusion 0.7334848783401952 1.886059744807746 0.059286904139292 1.0 0.9840933925754122 7 P17655,P41440 2 +Regulation of transcription by rna polymerase i 0.6320484878499588 1.8840079473577025 0.0595639004777859 1.0 0.9840933925754122 22 O75367,Q12824,P62875,Q9P0M6,Q13610,Q9NX58,Q9NZM5,Q9H6R0,Q9H583 9 +Regulation of proton transport 0.6505228050419068 1.8793026340107484 0.0602031822550168 1.0 0.9840933925754122 10 Q99653,P30405,Q9UHD1,Q9BSH4 4 +Positive regulation of cytokine production involved in immune response 0.6504858856313811 1.8791127991055565 0.0602290928667588 1.0 0.9840933925754122 10 Q9NR30,Q9NRA0,Q9NY93,P04439,P14174 5 +Negative regulation of release of cytochrome c from mitochondria 0.7560773162512329 1.8780162463024783 0.0603789426225092 1.0 0.9840933925754122 6 P31749 1 +Positive regulation of cell substrate junction organization 0.6784553882922317 1.8764502002507637 0.0605934868490241 1.0 0.9840933925754122 9 Q9HCM4,P62330 2 +Lung morphogenesis 0.6765742727390076 1.8672385089434544 0.0618682881542878 1.0 0.9840933925754122 9 Q13247,O60568 2 +Vesicle transport along microtubule 0.6484715826137195 1.8666145763603277 0.0619554305621581 1.0 0.9840933925754122 11 P42858 1 +Dosage compensation 0.6463515399172145 1.8552689517476195 0.0635578296022447 1.0 0.9905634773993892 12 Q9P0M6,Q96T37 2 +Morphogenesis of a polarized epithelium 0.6459796062854354 1.8548903311925569 0.0636118889758328 1.0 0.9905634773993892 13 O75083,O14641,P61586,P60953,Q13308 5 +Positive regulation of cell junction assembly 0.6450116928127619 1.8509343793427453 0.0641789940809332 1.0 0.9905634773993892 10 Q9HCM4,P41440 2 +Neural plate development 0.9049001503966762 1.84669336391866 0.0647915940230721 1.0 0.9905634773993892 3 O14641 1 +Mitochondrial respiratory chain complex assembly 0.4605795231193619 1.8446040950294629 0.0650951508825068 1.0 0.9905634773993892 44 O95139,P03915,O75438,O43676,Q9BSH4,Q86Y39,O43819,Q9BRT2,Q8IUX1,O95168,P28331,Q00059,Q96CU9,Q9BSK2 14 +Smooth muscle cell apoptotic process 0.7466610995875083 1.8374251684799687 0.0661471541362312 1.0 0.9905634773993892 6 P04179,O95140 2 +Positive regulation of blood vessel endothelial cell migration 0.6422810174350168 1.8353309719313071 0.0664566646687485 1.0 0.9905634773993892 13 P31749,Q16539,P46734 3 +Behavioral response to pain 0.8273230165545868 1.8299464239555023 0.0672579505932016 1.0 0.9905634773993892 4 P17655 1 +Response to pain 0.8273230165545868 1.8299464239555023 0.0672579505932016 1.0 0.9905634773993892 4 P17655 1 +Positive regulation of mitochondrial translation 0.6940930725753887 1.8226140737913588 0.0683618625464634 1.0 0.9905634773993892 8 Q9NYY8,Q9BRT2,Q567V2 3 +Rna modification 0.4266524165147377 1.8208240720733675 0.0686336038775508 1.0 0.9905634773993892 63 Q9NXH9,Q96T37,A0AV96,Q9UJA5,P22087,P46087,Q96DE0,Q969Y2,Q8TEA1,Q9UNQ2,Q6P6C2,O43709,Q9H0A0,Q9H974,Q8IY81,Q5VV42,O60832,Q9NPF4 18 +Endothelial cell morphogenesis 0.893904655238098 1.8048902061647931 0.0710918646738751 1.0 0.9905634773993892 3 O60568 1 +Rna export from nucleus 0.4023258685058211 1.800187577820932 0.0718310246283626 1.0 0.9905634773993892 52 Q8NI27,O75152,P78406,Q9ULX6,Q9HAU5,Q86V81,P37198,P49790,Q9Y3Y2,Q6P6C2,Q9BY77,Q86U42,Q5SRE5,Q86W42 14 +Positive regulation of smooth muscle cell apoptotic process 0.8194262620424542 1.7983082109769009 0.0721281792746539 1.0 0.9905634773993892 4 P04179,O95140 2 +Protein dna complex assembly 0.4018359408369154 1.7949628998867235 0.0726596111400295 1.0 0.9905634773993892 52 P10412,P50748,O75367,Q12824,P46100,P16403,P16402,O15160,Q9P0M6,Q96T23,Q5SSJ5,Q7Z7K6,Q92522,P62805,P07305 15 +Polyadenylation dependent rna catabolic process 0.7115258683370336 1.787365247027812 0.0738784747468432 1.0 0.9905634773993892 7 Q06265,Q8TCS8,Q13868 3 +Regulation of myeloid cell apoptotic process 0.7350882028797441 1.7873368911333811 0.0738830548963929 1.0 0.9905634773993892 6 P14174,P78536 2 +Sno s rna processing 0.6599554751142584 1.7855674095168237 0.0741693276960688 1.0 0.9905634773993892 9 Q5RKV6,O60832,Q13868 3 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.6319155320893013 1.7804382838666917 0.0750042610828947 1.0 0.9905634773993892 11 Q8N2F6 1 +Icosanoid transport 0.8136458638081681 1.7750988303838235 0.0758815700892803 1.0 0.9905634773993892 4 P14174 1 +Regulation of gene expression epigenetic 0.4415344949538343 1.772983361637806 0.0762314639448966 1.0 0.9905634773993892 45 Q15022,O75367,Q96T37,Q9Y6X9,Q13330,Q9P0M6,Q9NRA0,P51608,Q969T9,Q96ST3,Q7Z7K6,P07305 12 +Maintenance of blood brain barrier 0.7079078632985759 1.7710262367073657 0.0765563388782573 1.0 0.9905634773993892 7 P11047 1 +Telomeric loop disassembly 0.8850176166908096 1.7710094755771657 0.0765591260268157 1.0 0.9905634773993892 3 P54132 1 +Telomeric d loop disassembly 0.8850176166908096 1.7710094755771657 0.0765591260268157 1.0 0.9905634773993892 3 P54132 1 +Histone h3 k27 trimethylation 0.8829915560916859 1.7632740254253243 0.0778542839495854 1.0 0.9905634773993892 3 P10412,P16403 2 +Basement membrane assembly 0.7549596645553833 1.762612036566329 0.0779659456029673 1.0 0.9905634773993892 5 P11047,O60568 2 +Positive chemotaxis 0.7058309248977646 1.7616371398054065 0.0781306247105408 1.0 0.9905634773993892 7 Q9NWH9 1 +Rrna methylation 0.627211206895898 1.7589008679750846 0.0785943477359503 1.0 0.9905634773993892 10 Q9UNQ2,O43709,P22087,Q8IY81 4 +Positive regulation of dna dependent dna replication 0.7539314668010292 1.758236951385065 0.0787072003768543 1.0 0.9905634773993892 5 P46100,Q9ULV3 2 +Rna surveillance 0.6243390468660465 1.743996009042721 0.0811597857548611 1.0 0.9905634773993892 10 Q96B26,Q5RKV6,Q06265,Q13868 4 +5s class rrna transcription by rna polymerase iii 0.7502657298743823 1.7426267010451373 0.0813988428335319 1.0 0.9905634773993892 5 Q9Y5Q8,Q9Y5Q9,Q12789 3 +Placenta blood vessel development 0.7009938949239584 1.7397439990274302 0.0819039797292324 1.0 0.9905634773993892 7 Q96T37 1 +Mitotic nuclear membrane organization 0.7236121829970916 1.737457830293536 0.0823063912188506 1.0 0.9905634773993892 6 Q9H6H4,Q6NUK4 2 +Glomerulus development 0.803722534239933 1.7351587905240458 0.0827126834329572 1.0 0.9905634773993892 4 P11047 1 +Neuron projection regeneration 0.6222786794008979 1.728636872627458 0.0838741060295604 1.0 0.9905634773993892 12 P11047 1 +Folic acid metabolic process 0.6979465825935243 1.7259325635628222 0.0843595455618935 1.0 0.9905634773993892 7 P41440 1 +Succinyl coa metabolic process 0.8009049773755663 1.7237970068099358 0.084744495165097 1.0 0.9905634773993892 4 Q02218,P36957,Q9P2R7 3 +Spleen development 0.8717711853376222 1.7203613576597303 0.0853667765806807 1.0 0.9905634773993892 3 Q96T37 1 +Retrograde transport vesicle recycling within golgi 0.7439677718485969 1.7157637222606927 0.086205296492039 1.0 0.9905634773993892 5 Q96JB2,Q14746,Q9H9E3 3 +Glycosylation 0.389893095971069 1.7113394081391056 0.0870184755167762 1.0 0.9905634773993892 50 O75340,O43909,Q6ZXV5,P04844,Q16706,Q99653,Q96JB2,Q14165,O95394,Q9BXS4,Q9Y673,O60568,Q9H488,Q9H9E3,Q13724 15 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.6690967225661022 1.7046990860437456 0.0882505604060626 1.0 0.9905634773993892 8 Q8N5M9,P55809 2 +Positive regulation of glucose import 0.7411269843493415 1.7036291099134586 0.0884503995416476 1.0 0.9905634773993892 5 P31749,Q16539,Q9UKG1 3 +Insulin secretion involved in cellular response to glucose stimulus 0.6430311356694413 1.701892443638732 0.0887755325564705 1.0 0.9905634773993892 9 Q8N5M9,P55809 2 +Negative regulation of actin filament bundle assembly 0.6161774328847252 1.7015644017570946 0.0888370554975968 1.0 0.9905634773993892 10 Q9Y624,Q9NWH9 2 +Trna catabolic process 0.6160617424228146 1.7009621380635187 0.0889500970755821 1.0 0.9905634773993892 10 Q96B26,Q06265,Q13868 3 +P38mapk cascade 0.7938386284993744 1.6952615239471849 0.0900258203096497 1.0 0.9905634773993892 4 P46734 1 +Regulation of syncytium formation by plasma membrane fusion 0.7138189098262989 1.6947344940168343 0.0901257989817825 1.0 0.9905634773993892 6 P17655,P41440 2 +Positive regulation of syncytium formation by plasma membrane fusion 0.7138189098262989 1.6947344940168343 0.0901257989817825 1.0 0.9905634773993892 6 P17655,P41440 2 +Mitophagy 0.6129214703893662 1.68504576688674 0.0919797418241015 1.0 0.9905634773993892 15 Q9Y4P1,P53365 2 +Positive regulation of protein deubiquitination 0.7910949400541047 1.6841666649256777 0.0921494636099868 1.0 0.9905634773993892 4 Q9NZM5 1 +Positive regulation of keratinocyte differentiation 0.7361173746173177 1.682204138766146 0.092529261853008 1.0 0.9905634773993892 5 Q9P0M6 1 +Mitochondrial electron transport ubiquinol to cytochrome c 0.735666867833431 1.680275816664161 0.0929036640174123 1.0 0.9905634773993892 5 P14927,Q9UDW1,P08574,O14949 4 +Regulation of generation of precursor metabolites and energy 0.4825724581497702 1.6795835370508037 0.0930383729995458 1.0 0.9905634773993892 40 O14548,P62140,Q9BSH4,Q9BSK2,Q9BRT2,P31749,Q9NZM5,P30405 8 +Rrna modification 0.6117551774082552 1.678699811320543 0.0932105627519166 1.0 0.9905634773993892 15 P22087,Q9UNQ2,O43709,Q9H0A0,Q8IY81,O60832 6 +Negative regulation of smooth muscle cell proliferation 0.6862657443116058 1.672861055675445 0.0943546519781812 1.0 0.9905634773993892 7 P61586,P04179,Q15637,O95140 4 +Acetyl coa biosynthetic process from pyruvate 0.7078210504953641 1.6684999371927032 0.0952165243872706 1.0 0.9905634773993892 6 P08559,Q15120,P10515,O95563 4 +Regulation of histone h3 k9 trimethylation 0.7067872427384997 1.663972957206125 0.0961178337393371 1.0 0.9905634773993892 6 Q12824,P46100 2 +Histone h3 k9 trimethylation 0.7067872427384997 1.663972957206125 0.0961178337393371 1.0 0.9905634773993892 6 Q12824,P46100 2 +Acetyl coa biosynthetic process 0.6353447665365725 1.6637380392366954 0.0961647909830243 1.0 0.9905634773993892 9 P08559,Q15120,P10515,O95563 4 +Positive regulation of membrane potential 0.706042346648141 1.6607101847926882 0.0967716669090394 1.0 0.9905634773993892 6 P31749 1 +Endocrine hormone secretion 0.8552644565648453 1.6570166288006754 0.0975161131925341 1.0 0.9905634773993892 3 P82094 1 +Proton transporting two sector atpase complex assembly 0.7838806611711792 1.654954433266468 0.0979337413261693 1.0 0.9905634773993892 4 Q8N511 1 +Syncytium formation 0.6584975762047292 1.654401135825669 0.0980460358513406 1.0 0.9905634773993892 8 P17655,P41440 2 +Nucleosome organization 0.3945148082403759 1.651879097410603 0.0985591999797508 1.0 0.9905634773993892 55 P10412,O75367,Q12824,P46100,P16403,P16402,Q9P0M6,Q9GZN1,P17096,Q96T23,Q5SSJ5,Q92522,Q9NPF5,P62805,P07305 15 +Positive regulation of nitric oxide metabolic process 0.7284292917772794 1.6492611298361295 0.0990941492126316 1.0 0.9905634773993892 5 P31749 1 +Regulation of mitochondrial gene expression 0.6070088747877374 1.6492474070333445 0.099096959390311 1.0 0.9905634773993892 14 Q9BSH4,Q9NYY8,Q9BRT2 3 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.8516877261475272 1.6432594764343451 0.1003292588229212 1.0 0.9905634773993892 3 Q13740 1 +Cell aging 0.5539173266589937 1.6412776574864476 0.1007397918020525 1.0 0.9905634773993892 30 Q8TCS8,P42771,Q16539,Q15554,P14174,P17096,Q9NX47,O43324,Q96SB8,P46734 10 +Regulation of animal organ morphogenesis 0.6556194812072487 1.6407151869426266 0.1008565508984493 1.0 0.9905634773993892 8 P60953,O14641,Q13308 3 +Thrombin activated receptor signaling pathway 0.8508404262546604 1.6399989566813404 0.1010053838774942 1.0 0.9905634773993892 3 Q13576 1 +Establishment of planar polarity of embryonic epithelium 0.8494588132198497 1.634681072135108 0.1021159223956629 1.0 0.991165181744449 3 O14641 1 +Transcription by rna polymerase i 0.5582428314555313 1.6318358595440088 0.1027140688733554 1.0 0.991165181744449 29 O75367,Q12824,P62875,O15446,Q9GZS1,O15160,Q9P0M6,Q13610,Q9NX58,Q9NZM5,P17480,Q9H6R0,Q9H583 13 +Dicarboxylic acid transport 0.603005184419978 1.627623271497434 0.1036047915408333 1.0 0.991165181744449 14 P41440 1 +Positive regulation of insulin secretion 0.602633778511485 1.626844859223759 0.1037700514820874 1.0 0.991165181744449 11 Q8NE86,P55809 2 +Cytokine production involved in immune response 0.6006562971777228 1.6164257162358506 0.1060023020543345 1.0 0.9974499882048892 11 Q9NR30,Q9NRA0,Q9NY93,P04439,P14174 5 +Epigenetic maintenance of chromatin in transcription competent conformation 0.6959413897183423 1.616392203480039 0.1060095429566043 1.0 0.9974499882048892 6 Q969T9,O75367 2 +Notch signaling pathway 0.589108123350559 1.6144483283284048 0.1064302161811543 1.0 0.9977714399367756 21 P31749,Q96T37,Q9Y5A9,Q9Y6I3 4 +Columnar cuboidal epithelial cell development 0.5988822991926481 1.6113021553293774 0.1071138812328769 1.0 0.9987529623940086 10 Q15382 1 +Establishment of epithelial cell apical basal polarity 0.6941553615642023 1.608542054627206 0.1077165133994624 1.0 0.9987529623940086 6 P60953,Q13308 2 +Regulation of oxidative phosphorylation 0.5983375573113442 1.6084522705438429 0.1077361615811896 1.0 0.9987529623940086 10 O14548,Q9BSK2,Q9BRT2 3 +Negative regulation of dna recombination 0.5950096103178137 1.6084077967382815 0.1077458951969601 1.0 0.9987529623940086 18 P10412,P54132,P16403,Q15554,Q92522,P07305 6 +Glomerular epithelial cell differentiation 0.8422561090091911 1.6069329721665309 0.1080690724958959 1.0 0.9987529623940086 3 P11047 1 +Glomerular epithelium development 0.8422561090091911 1.6069329721665309 0.1080690724958959 1.0 0.9987529623940086 3 P11047 1 +Convergent extension 0.8421063652024131 1.6063556640376422 0.108195786401019 1.0 0.9987529623940086 3 O14641 1 +Rrna catabolic process 0.5971538699652137 1.594785131300893 0.1107602931135556 1.0 0.9987529623940086 13 Q9Y6V7,Q13868,Q5RKV6,Q96B26,Q06265 5 +Replication fork processing 0.5955175539372214 1.5893268003511634 0.1119866311339292 1.0 0.9987529623940086 11 Q86V81,P46100,P54132 3 +Mitochondrial rna metabolic process 0.5454627481518871 1.5851219841773143 0.1129386215677676 1.0 0.9987529623940086 30 Q9NYY8,Q7L8L6,Q9BSK2,Q969Z0,Q00059,Q9UGM6 6 +Ncrna transcription 0.550632695241394 1.582127152973292 0.1136205460851982 1.0 0.9987529623940086 29 O75367,Q12824,P62875,Q9H9Y6,O15446,O15160,P46100,Q9P0M6,Q13610,Q9H2V7,Q12789,Q9BYG3,Q9Y5Q8,Q9Y5Q9,Q9NZM5,Q8WUA4 16 +Atp synthesis coupled electron transport 0.4608541407738417 1.5774712365593937 0.1146871354077596 1.0 0.9987529623940086 41 O14548,P20674,P19404,O95139,O75438,O43676,Q16795,O14949,O95168,O75380,P28331,P08574,P03915,Q9UDW1,P14927 15 +Trna 5 leader removal 0.7114808157256712 1.5763866711654646 0.1149367182478753 1.0 0.9987529623940086 5 P78346,Q99575,Q8N5L8 3 +Rna methylation 0.5250424725109637 1.5742808733050204 0.1154225295977389 1.0 0.9987529623940086 33 Q9NXH9,Q96T37,Q9UJA5,P22087,Q969Y2,Q8TEA1,Q9UNQ2,O43709,Q8IY81 9 +Signal transduction by p53 class mediator 0.3831808444572117 1.5742576721690764 0.1154278911204167 1.0 0.9987529623940086 53 O15164,P60866,P46100,Q8N2F6,P62841,P46087,Q07812,Q7LG56,P31749,O60934,P62081,O43324,Q9NZM5,Q9BVC6,Q9H7B2,P14174 16 +Mrna export from nucleus 0.495302709417077 1.5737105612063669 0.1155543791030504 1.0 0.9987529623940086 37 O75152,Q9ULX6,Q86V81,Q9Y3Y2,Q6P6C2,Q9BY77,Q8NI27,Q86W42 8 +Regulation of glucose import 0.5914091773388904 1.5721728892254063 0.1159104610199679 1.0 1.0 10 Q06124,Q16539,P31749,P52789,Q9UKG1 5 +Trna aminoacylation for mitochondrial protein translation 0.6398536935469215 1.5655513533799437 0.1174536861749837 1.0 1.0 8 Q9UGM6,Q9BW92,Q9NP81 3 +Sphingolipid mediated signaling pathway 0.7614996734828792 1.5639927659234785 0.1178192672989881 1.0 1.0 4 P31749 1 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.5897985002729568 1.563730578347808 0.117880853459112 1.0 1.0 10 Q5RKV6,Q06265,Q13868 3 +Megakaryocyte differentiation 0.61406304789989 1.5576663723896162 0.1193123559615734 1.0 1.0 9 Q96T37 1 +Activation induced cell death of t cells 0.7059990026958003 1.5527479725950235 0.1204833566063139 1.0 1.0 5 P31749 1 +Positive regulation of epithelial cell migration 0.5405712707886687 1.552614109398628 0.1205153528271485 1.0 1.0 30 Q9HCM4,Q9NWH9,P62330,Q16539,P31749,O75122,P46734,P78536 8 +Defense response to bacterium 0.5877315681908701 1.5521920186649796 0.1206162852609569 1.0 1.0 16 P81605,P62820,P82094 3 +Cellular senescence 0.577946220733574 1.5493754646228597 0.1212914883045113 1.0 1.0 21 Q8TCS8,P42771,Q16539,Q15554,P17096,O43324,Q96SB8,P46734 8 +Nuclear ncrna surveillance 0.6800143512167196 1.54624962883291 0.1220442918928164 1.0 1.0 6 Q06265,Q13868 2 +Regulation of guanyl nucleotide exchange factor activity 0.7042544707702031 1.5452187209453956 0.1222933675704018 1.0 1.0 5 Q9NWH9 1 +Maturation of ssu rrna 0.4991284863942142 1.5432888439704324 0.1227607091977243 1.0 1.0 36 Q8NEF9,Q9BSC4,Q12788,Q13895,P55769,Q2NL82,Q68CQ4,O15213,P62857,Q9Y2P8,P39019,Q9H0A0,P62312,P82912,Q9H583 15 +Polarized epithelial cell differentiation 0.6347081190129674 1.540954611786673 0.1233278329484908 1.0 1.0 8 P61586,P60953,Q13308 3 +Leucine metabolic process 0.7028682351059784 1.5392336850868693 0.1237472568167321 1.0 1.0 5 Q96RQ3,O15382 2 +Regulation of maintenance of sister chromatid cohesion 0.7541752788770026 1.5341252802204506 0.1249988351327899 1.0 1.0 4 P46100 1 +L alpha amino acid transmembrane transport 0.5824217191506273 1.52502951330591 0.127251736517765 1.0 1.0 10 O60831 1 +Cellular response to interferon beta 0.6750502209862332 1.5243275153672182 0.1274269170151831 1.0 1.0 6 P17655,Q8TCS8 2 +Response to interferon beta 0.6750502209862332 1.5243275153672182 0.1274269170151831 1.0 1.0 6 P17655,Q8TCS8 2 +Regulation of glycogen metabolic process 0.6984380028785138 1.5200938144652647 0.1284873989975308 1.0 1.0 5 P31749 1 +Regulation of glucan biosynthetic process 0.6984380028785138 1.5200938144652647 0.1284873989975308 1.0 1.0 5 P31749 1 +Leydig cell differentiation 0.8187999454304651 1.5163116612543657 0.1294405643610034 1.0 1.0 3 P82094 1 +L serine metabolic process 0.6969635003762427 1.5137194545170465 0.130097008600265 1.0 1.0 5 P78330,Q9Y617,P34896 3 +Regulation of cellular respiration 0.5787472745112435 1.508642270082032 0.1313902258294408 1.0 1.0 17 O14548,Q9BRT2,P30405,Q9NZM5,Q9BSK2 5 +3 utr mediated mrna stabilization 0.6041689570599529 1.5081699253402754 0.1315110423801704 1.0 1.0 9 P16989,Q16539 2 +Positive regulation of phospholipid biosynthetic process 0.7476507040481467 1.5074830181784875 0.1316868934575037 1.0 1.0 4 Q99653,P17655 2 +Mitochondrial transcription 0.6494819058253338 1.5045431235787872 0.1324415784460271 1.0 1.0 7 Q9BSK2 1 +Transcription initiation from rna polymerase i promoter 0.669171965308896 1.4983348750688337 0.134046267400608 1.0 1.0 6 P17480,Q12824,O15160 3 +Rna polymerase i preinitiation complex assembly 0.669171965308896 1.4983348750688337 0.134046267400608 1.0 1.0 6 P17480,Q12824,O15160 3 +Positive regulation of cytokinesis 0.5787672205408707 1.4960081309109363 0.1346515363386489 1.0 1.0 13 Q9Y2S7,P37198,P61586,Q9H8V3,P60953,Q7Z7K6,P08069 7 +Positive regulation of transcription by rna polymerase i 0.5774215177210917 1.4952208656953716 0.1348568096880837 1.0 1.0 16 Q12824,Q13610,Q9NX58,Q9H6R0,Q9H583 5 +Electron transport chain 0.4104591989298334 1.4910415844467195 0.1359505774479248 1.0 1.0 71 Q12797,Q16795,O75438,O43676,P38117,P30038,Q6FI81,Q9UDW1,P31040,P19404,P11766,P28331,P14927,O14548,P20674,P09622,O75380,P08574,P03915,O43837,P23368,O75489,O95139,O43819,P43304,P04179,O95168,P47985,Q9P0J0,Q14554,Q9BQG0,O14949 32 +Bundle of his cell to purkinje myocyte communication 0.7429864253393672 1.4884177059621344 0.1366407700064535 1.0 1.0 4 Q14126,P14923,Q9HD47 3 +Ncrna 3 end processing 0.5580249433308172 1.4868665882506509 0.1370500503035403 1.0 1.0 24 P22087,Q13868,Q5RKV6,Q8N201,Q96B26,Q9NVH2,Q06265,O60832 8 +Vascular associated smooth muscle cell proliferation 0.5760877608606572 1.4866056996987196 0.1371189815639386 1.0 1.0 11 Q9Y2S7,O95140,Q5SW96,P04179,P61586 5 +Rrna 3 end processing 0.6229841401629161 1.4848091928872624 0.1375943760231186 1.0 1.0 8 Q06265,Q13868 2 +Cellular response to vitamin 0.6645641486180265 1.4779359552395834 0.1394249213503089 1.0 1.0 6 O15164,P20020,Q8TB36 3 +Rab protein signal transduction 0.6643831052960854 1.477134062604906 0.1396397044230295 1.0 1.0 6 Q5VZ89,Q15286 2 +Ubiquinone metabolic process 0.8085042219541867 1.4764299163821013 0.1398285164940096 1.0 1.0 3 Q8NI60,P22570 2 +Amide transport 0.4487933626585049 1.4763824935861078 0.1398412396551915 1.0 1.0 41 Q92930,P55809,Q03518,O15439,Q9BRT2,P62820,Q8NE86,Q8N5M9,P41440 9 +Positive regulation of mitochondrial membrane potential 0.7391781885983002 1.4728403895568714 0.1407940787013528 1.0 1.0 4 P31749 1 +Positive regulation of map kinase activity 0.5737177004997304 1.4705542121525947 0.1414117144465367 1.0 1.0 12 O14641 1 +Regulation of electron transfer activity 0.7383177647294412 1.4693195768701657 0.1417461293244972 1.0 1.0 4 Q9BSH4 1 +Regulation of actin filament based movement 0.6416109898880441 1.468332022474361 0.1420140566202268 1.0 1.0 7 Q9HD47,Q99996,P15924,Q14126,P14923 5 +Vascular associated smooth muscle cell apoptotic process 0.8061570310669057 1.4673304446007154 0.14228618565317 1.0 1.0 3 O95140 1 +Activated t cell proliferation 0.6410721009649856 1.4658507737132138 0.142688945195065 1.0 1.0 7 Q9BY67,Q9HCL2 2 +Positive regulation of myeloid leukocyte cytokine production involved in immune response 0.6409041744151657 1.4650775259616502 0.1428997674937904 1.0 1.0 7 P14174,Q9NR30,Q9NY93 3 +Regulation of actin cytoskeleton reorganization 0.5953682110350462 1.4640666380785072 0.1431757416764549 1.0 1.0 9 Q9Y624,Q13576 2 +Response to fungus 0.640487583630507 1.4631591569551576 0.143423833788034 1.0 1.0 7 P81605 1 +Ketone biosynthetic process 0.7365039951070212 1.4618961962198675 0.1437696575040987 1.0 1.0 4 Q8NI60,P22570 2 +Protein kinase a signaling 0.6390572353355339 1.4565714149210904 0.1452347230343385 1.0 1.0 7 P14174,P51153 2 +Morphogenesis of an epithelial sheet 0.5695239495649911 1.451833317356246 0.1465479574669901 1.0 1.0 11 O75122,O14641 2 +Epithelial cell development 0.3967476157733375 1.4506173499335209 0.1468864413582542 1.0 1.0 46 Q9HCM4,P11047,Q9NWH9,P31749,Q9Y624,O60568,P51153,P62820,Q15382 9 +Cellular response to exogenous dsrna 0.637691736040468 1.450280797149459 0.1469802317477981 1.0 1.0 7 P41440 1 +Organic anion transport 0.4455431669666775 1.4491721446164347 0.147289514497559 1.0 1.0 41 O43808,O60831,O15439,P14174,P08195,P41440,Q8TB61 7 +T cell homeostasis 0.6366966197734809 1.4456955409955097 0.1482626155753346 1.0 1.0 7 P42574,P31749,Q9HCL2,Q07812 4 +Establishment or maintenance of monopolar cell polarity 0.5671217249045054 1.4446066968047806 0.1485683906739994 1.0 1.0 10 P60953,Q13308 2 +Dna templated transcription initiation 0.4533872919564474 1.4411148995347784 0.1495522249018555 1.0 1.0 40 Q12824,Q9ULK4,Q00403,Q9GZS1,O15160,O60244,O60264,P13984,Q12789,Q9Y5Q8,Q96T23,P62487,Q00059,P17480,P62805 15 +Snrna processing 0.5676884857404758 1.4378413534352057 0.1504790729165439 1.0 1.0 15 Q13868,Q5RKV6,Q8N201,Q9NVH2,Q06265 5 +Protein insertion into mitochondrial inner membrane 0.6554459036005915 1.4375127594724086 0.1505723499412543 1.0 1.0 6 Q9Y5J9,Q53H12,Q9P0J0,O60220 4 +Extracellular matrix disassembly 0.5654225195676006 1.4356652607879692 0.1510976148625862 1.0 1.0 10 P11047,P41440 2 +Antimicrobial humoral response 0.6546757360223957 1.43409526120793 0.1515450800339168 1.0 1.0 6 P39019,P05204,P04439,P04406 4 +Regulation of aerobic respiration 0.5669979188258124 1.434056347449994 0.1515561836386205 1.0 1.0 15 Q9NZM5,O14548,Q9BSK2,Q9BRT2 4 +Regulation of signal transduction by p53 class mediator 0.4689404456389973 1.432550142749042 0.1519864386030684 1.0 1.0 38 O15164,P60866,Q8N2F6,P62841,P46087,Q7LG56,P31749,O43324,Q9NZM5,Q9H7B2,P14174 11 +Positive regulation of rrna processing 0.6338156065619753 1.4324162806384388 0.1520247219431616 1.0 1.0 7 Q15061,Q9UNQ2,Q9H583,O43709 4 +Basement membrane organization 0.6335552995206016 1.4312161639791714 0.1523682723721768 1.0 1.0 7 P11047,O60568 2 +Glycoprotein biosynthetic process 0.3736768408017333 1.4310695240806317 0.1524102906050419 1.0 1.0 55 O75340,O43909,Q6ZXV5,P04844,Q16706,Q99653,Q96JB2,Q14165,O95394,Q9BXS4,Q9Y673,O60568,Q9H488,Q13724 14 +Regulation of macrophage migration 0.7286113277269984 1.4295706868686122 0.1528402736758387 1.0 1.0 4 P14174 1 +Regulation of macrophage chemotaxis 0.7286113277269984 1.4295706868686122 0.1528402736758387 1.0 1.0 4 P14174 1 +Extracellular matrix assembly 0.652310345625259 1.4235963450234763 0.1545633544960631 1.0 1.0 6 P11047,O60568 2 +Peripheral nervous system development 0.5626367040414868 1.4210028985630891 0.1553159167906983 1.0 1.0 10 P11047 1 +Regulation of anoikis 0.6755292849542247 1.4208555982306712 0.1553587435131458 1.0 1.0 5 Q9Y3E5,Q07820,Q9BQG0 3 +Regulation of skeletal muscle cell differentiation 0.7263432227565668 1.4202751510428064 0.1555275924566594 1.0 1.0 4 Q9BRT2 1 +Fatty acid alpha oxidation 0.7937273823884161 1.4191061154016835 0.1558680813164061 1.0 1.0 3 A1L0T0,O43808 2 +Peptide transport 0.4882862517069937 1.4095538740979754 0.1586714550644818 1.0 1.0 35 Q92930,P55809,Q03518,O15439,Q9BRT2,Q8NE86,Q8N5M9,P62820 8 +Retinal ganglion cell axon guidance 0.7904101326900159 1.4062268807143978 0.159656764490808 1.0 1.0 3 Q13740,P83731 2 +Positive regulation of focal adhesion assembly 0.647584895754542 1.402609912645887 0.1607331942491923 1.0 1.0 6 Q9HCM4 1 +Cell death in response to hydrogen peroxide 0.6057549316514008 1.4020916594634407 0.1608878773768398 1.0 1.0 8 Q9NWH9 1 +Endothelial cell chemotaxis 0.7214994788356968 1.4004155178888875 0.1613889257749434 1.0 1.0 4 Q9NWH9 1 +Oxidative phosphorylation 0.3882477995505711 1.4000540746443408 0.1614971261615683 1.0 1.0 64 P56134,O75438,O43676,P48047,P61586,P30405,Q9UJZ1,Q9UDW1,P19404,P28331,P14927,O14548,P20674,Q9BRT2,O75380,P08574,P03915,O95139,O95168,Q9BSK2,Q16795,O14949 22 +Cell fate determination 0.7884958619216589 1.398793316693662 0.1618749710404539 1.0 1.0 3 P60953 1 +Positive regulation of protein localization to cell surface 0.6467097207700994 1.3987214395936831 0.1618965324530219 1.0 1.0 6 P31749,Q9HD47 2 +Mitochondrial electron transport cytochrome c to oxygen 0.6260732462987153 1.3967015348150011 0.1625033424721489 1.0 1.0 7 O14548 1 +Sertoli cell differentiation 0.6697531741439058 1.3957760154223982 0.1627819551060452 1.0 1.0 5 P46100,P51153 2 +Telomere maintenance via recombination 0.6686783343391631 1.391107071159482 0.1641929609486487 1.0 1.0 5 Q15554,Q92878,Q96SB8,P18887 4 +Positive regulation of extracellular matrix organization 0.6686578732113923 1.3910181852494232 0.1642199123331178 1.0 1.0 5 O75122 1 +Cellular response to vitamin d 0.6675677138621551 1.3862820784244794 0.1656607870535968 1.0 1.0 5 O15164,P20020,Q8TB36 3 +Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.5582601653036124 1.385582126638781 0.1658745390023686 1.0 1.0 13 Q14137,Q6DKI1,Q9BYG3,Q9H7B2,Q9BZE4,Q9NVP1,Q8IY81 7 +Regulation of dna recombination 0.3652926247973695 1.3842200138885026 0.1662910969147482 1.0 1.0 53 P10412,P16403,P54132,Q5RKV6,Q86V81,Q15554,Q9HAF1,Q92522,Q8TAF3,Q9NPF5,P07305 11 +Negative regulation of protein maturation 0.6433433423316586 1.3837597786249474 0.1664320225638853 1.0 1.0 6 Q9UMY4 1 +Lipopolysaccharide mediated signaling pathway 0.5790248206047086 1.3820280407155494 0.1669630914457291 1.0 1.0 9 P31749,P14174 2 +Peptidyl lysine trimethylation 0.5540925535371318 1.3776007115593925 0.168326601138786 1.0 1.0 18 P10412,Q12824,P46100,P16403,P16402,Q13610,P51608,Q6UXN9 8 +Regulation of hippo signaling 0.7147983758917186 1.3729246267124509 0.1697757797827801 1.0 1.0 4 Q16539,P46734 2 +Polyadenylation dependent snorna 3 end processing 0.6395566581848627 1.366922043624862 0.17164974173865 1.0 1.0 6 Q13868 1 +Single strand break repair 0.7124990562597424 1.3634881876790257 0.1727287047228722 1.0 1.0 4 P09874,Q15554 2 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.5465105667492913 1.3533955914943692 0.1759292850817995 1.0 1.0 20 Q8N2F6,Q7LG56,P62081,Q9BVC6,P14174 5 +Regulation of muscle organ development 0.6362316495545542 1.3521308752312278 0.1763334518551047 1.0 1.0 6 P41440 1 +Signal release 0.3718245726470152 1.3498626025063527 0.1770600594967499 1.0 1.0 58 Q92930,P55809,P35080,O15439,Q9BRT2,P82094,P62820,Q8NE86,Q8N5M9,P14174 10 +Mrna cleavage involved in mrna processing 0.6157386131890514 1.3489768189059943 0.1773444119706069 1.0 1.0 7 O43809 1 +Nucleolus organization 0.5721784441054463 1.347630123083994 0.1777773769805393 1.0 1.0 9 Q9H9Y6,O75367 2 +Negative regulation of intrinsic apoptotic signaling pathway 0.4855914193163825 1.3418835806843568 0.1796337463279886 1.0 1.0 34 Q8N2F6,Q7LG56,Q07820,P04179,P31749,P16989,P30405,P14174,Q9P0J0 9 +Negative regulation of leukocyte chemotaxis 0.773522316043437 1.3406223966539057 0.1800430818536618 1.0 1.0 3 O94813,P14174 2 +Regulation of intrinsic apoptotic signaling pathway 0.3609948217997075 1.3388060870834355 0.1806338086545171 1.0 1.0 53 Q8N2F6,P31689,Q7LG56,Q07820,Q07812,P04179,P31749,P16989,P62081,P30405,P14174,Q9P0J0 12 +Regulation of phagocytosis 0.5487757117430567 1.3334409604546933 0.1823871381203621 1.0 1.0 14 Q92614 1 +Histone h2a acetylation 0.5685791300033222 1.3295435736118708 0.1836687000559278 1.0 1.0 9 Q9NPF5,Q9NRA0,Q9HAF1 3 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.7040723981900463 1.328893128595725 0.1838832311561571 1.0 1.0 4 P08559,P09622,O95563 3 +Developmental pigmentation 0.5676617640848735 1.324933752590275 0.185193124796442 1.0 1.0 9 Q07812,Q96AX1,P04179,O75787 4 +Regulation of skeletal muscle tissue development 0.6531099692054936 1.3234244454972015 0.1856942668101591 1.0 1.0 5 P41440 1 +Isoleucine metabolic process 0.6523711285254588 1.3202103829652228 0.1867647863200794 1.0 1.0 5 O15382 1 +Regulation of dna damage response signal transduction by p53 class mediator 0.5446296735926317 1.3198205073859754 0.1868949530185519 1.0 1.0 11 P14174 1 +Positive regulation of endothelial cell migration 0.5371878729053575 1.3114984865545347 0.1896894047151227 1.0 1.0 21 Q9NWH9,Q16539,P31749,P46734,P78536 5 +Cell junction maintenance 0.5864484228811704 1.3092264893134733 0.1904576418402792 1.0 1.0 8 Q9BRK5 1 +Regulation of neurotransmitter transport 0.5442366047673205 1.308794715560973 0.1906038974736641 1.0 1.0 14 P41440,P35080 2 +Vesicle docking involved in exocytosis 0.5424441230720249 1.3082318225179808 0.1907946915672145 1.0 1.0 11 Q92930,Q7Z6M1 2 +Leucine catabolic process 0.69713423831071 1.3003997644592564 0.1934639906263355 1.0 1.0 4 Q96RQ3,Q9HCC0,P26440 3 +Regulation of sister chromatid cohesion 0.5401905589718294 1.2962845276054062 0.1948774771417394 1.0 1.0 11 O75367,P46100,O43683,P39748,O60216,P35222 6 +Positive regulation of fat cell differentiation 0.5836218257485002 1.2956248936451702 0.1951047484351729 1.0 1.0 8 P31749 1 +Trna processing 0.379750717971264 1.2870416388349089 0.1980797753451002 1.0 1.0 46 Q969Y2,Q8TEA1,O15091,Q9H0A0,Q15046,Q5VV42,Q12849,Q9NPF4,Q9NXH9,Q9Y3I0,Q9BV44,Q8N5L8,P62312,O75127,Q9H974,Q9UJA5,Q99575,Q5JTZ9,P78346,Q9NXG2 20 +Positive regulation of secretion 0.3615834929020079 1.2834847045271751 0.1993223148896958 1.0 1.0 56 Q92930,P55809,Q92614,P62330,P82094,P20339,Q8NE86,P14174 8 +Carbohydrate mediated signaling 0.6437314244034539 1.2826193129708616 0.1996254805863582 1.0 1.0 5 P17480,Q12824,P51532 3 +Negative regulation of cell matrix adhesion 0.6198869343390752 1.279360054306366 0.2007702937092501 1.0 1.0 6 Q9P258,P42771,P63167,O75122 4 +Ketone catabolic process 0.7575832358291588 1.2786865755683487 0.2010074489059601 1.0 1.0 3 P55809 1 +Sertoli cell development 0.6912745804687104 1.2763333856578154 0.2018376932213184 1.0 1.0 4 P51153 1 +Myeloid leukocyte cytokine production 0.5783716668566714 1.2703626361047553 0.2039554861283661 1.0 1.0 8 P14174,Q9NR30,Q9NY93 3 +Anoikis 0.5562081053116262 1.2673886024407388 0.2050163731499446 1.0 1.0 9 P31749,Q9Y3E5,Q07820,Q9BQG0 4 +Antimicrobial humoral immune response mediated by antimicrobial peptide 0.6398126757223532 1.2655668209530642 0.2056682110910632 1.0 1.0 5 P05204,P39019,P04406 3 +Pancreas development 0.534844491677526 1.2628925994471911 0.2066277799100571 1.0 1.0 12 Q9NWH9,Q15382 2 +Regulation of cardiac muscle cell action potential 0.5969618913438488 1.2621860098019375 0.2068818616414365 1.0 1.0 7 Q14126,Q9HD47,Q99996,P15924,P14923 5 +Positive regulation of organ growth 0.5968987941198385 1.2618943173474264 0.2069868170911277 1.0 1.0 7 P31749,P16989,Q16539 3 +Rrna metabolic process 0.5579654181598322 1.261616123132676 0.2070869516645324 1.0 1.0 177 P22087,P55769,Q2NL82,Q68CQ4,P62857,Q9BYD6,Q9Y3A5,O15446,Q8TCT8,Q9Y5A9,P46087,P62081,Q8TDN6,Q96B26,Q13868,Q9NR30,Q99848,O15213,P62847,Q99547,P62312,Q96DE0,Q9Y5Q8,Q14137,Q9BSC4,O00541,P18077,P50914,Q9NX58,Q9H501,P39019,Q8WUA4,P82912,O15160,Q9GZS1,Q9NQ55,Q9Y4W2,Q9H2V7,Q8TDD1,O43709,P57678,Q9NZM5,P61353,Q13206,Q9H9Y6,Q9H7B2,Q9GZR2,Q9Y2L1,Q9P0M6,Q96GQ7,Q9Y3A2,Q8IY81,Q9Y237,Q8NEF9,O75367,Q12824,Q9BVJ6,Q9ULW3,P62424,Q9NY93,O00567,P08708,Q13610,Q13601,Q9Y6V7,O95478,Q6DKI1,Q5RKV6,Q9H583,P62841,Q12789,Q9H0A0,Q9NVP1,O60832,O76021,Q12788,Q14684,Q9BYG3,Q9H0S4,Q9UNQ2,Q9Y2P8,Q9Y5Q9,Q9BZE4,Q9H9Y2,Q13895,Q06265 86 +Attachment of gpi anchor to protein 0.7530278106062831 1.26099031279538 0.2073123373523566 1.0 1.0 3 Q96S52 1 +Positive regulation of chemokine production 0.596505322658675 1.2600753446258333 0.2076421835371327 1.0 1.0 7 P14174 1 +Negative regulation of telomere capping 0.686576168929111 1.2570374685834027 0.2087400682701994 1.0 1.0 4 O60934,P18887,Q15554 3 +Positive regulation of cyclin dependent protein kinase activity 0.6145228655646855 1.2554652671720672 0.2093099090831485 1.0 1.0 6 P31749 1 +Intrinsic apoptotic signaling pathway in response to osmotic stress 0.7512062726176268 1.2539155586558397 0.2098726992351527 1.0 1.0 3 P42574,P16989 2 +Neuron intrinsic apoptotic signaling pathway in response to oxidative stress 0.6843705817290298 1.2479802525701118 0.2120382890257057 1.0 1.0 4 P09874,Q07820 2 +Regulation of macrophage activation 0.6121634036549979 1.2449544265238242 0.2131485027838124 1.0 1.0 6 Q92614 1 +Heterotypic cell cell adhesion 0.5508046131853356 1.2402563364966852 0.2148805968675948 1.0 1.0 9 Q14126,Q08722,P15924,P41440,P14923 5 +Branching morphogenesis of an epithelial tube 0.5313026758000636 1.2402520336323488 0.2148821878860536 1.0 1.0 16 Q96T37 1 +Hindbrain morphogenesis 0.5500290016540197 1.2363631391102103 0.2163236112562949 1.0 1.0 9 P18887,Q06124,P63167,Q15058,O15020,O15228 6 +Positive regulation of hormone secretion 0.5296542589316663 1.234590746041618 0.2169828547836623 1.0 1.0 17 Q92930,Q8NE86,P55809,P82094 4 +Neutrophil migration 0.5305074928539012 1.234344254441564 0.217074651962005 1.0 1.0 14 Q07021,O75083,P35613,Q8NE86,O94813,P61011,Q8N5M9 7 +Adp transport 0.6803755962602377 1.2315772290724585 0.218107051340811 1.0 1.0 4 O43808 1 +Positive regulation of cell matrix adhesion 0.526329119702731 1.2298858188051969 0.2187398653814389 1.0 1.0 10 Q9HCM4,P46939,Q9Y2S7 3 +Transcription preinitiation complex assembly 0.5285818529976714 1.2294941346853838 0.2188865955965595 1.0 1.0 12 P17480,Q12824,Q00403,O15160 4 +Pyrimidine deoxyribonucleotide biosynthetic process 0.6312400155064468 1.228266055190345 0.2193471091915657 1.0 1.0 5 P34896 1 +Atp transport 0.6076425781821653 1.2248160640185115 0.2206445310171474 1.0 1.0 6 P05141,O43808,Q08722 3 +Cellular response to acidic ph 0.7429198993399792 1.2217443903832972 0.2218043038549795 1.0 1.0 3 Q99653 1 +Response to acidic ph 0.7429198993399792 1.2217443903832972 0.2218043038549795 1.0 1.0 3 Q99653 1 +Desmosome organization 0.7427623642943368 1.2211330123304427 0.222035662230313 1.0 1.0 3 P14923,Q14126 2 +Regulation of ventricular cardiac muscle cell action potential 0.7427623642943368 1.2211330123304427 0.222035662230313 1.0 1.0 3 P14923,Q14126 2 +Cardiac muscle cell cardiac muscle cell adhesion 0.7427623642943368 1.2211330123304427 0.222035662230313 1.0 1.0 3 P14923,Q14126 2 +Ventricular cardiac muscle cell action potential 0.7427623642943368 1.2211330123304427 0.222035662230313 1.0 1.0 3 P14923,Q14126 2 +Response to growth hormone 0.677724523761535 1.2206943454472767 0.2222017695132563 1.0 1.0 4 P31749 1 +Positive regulation of translational initiation 0.5277363141869584 1.2190880093161245 0.222810790438559 1.0 1.0 15 Q9Y5A9 1 +Positive regulation of sister chromatid cohesion 0.6283027199303816 1.215488480389673 0.2241798397354326 1.0 1.0 5 O75367,O60216,P39748 3 +Negative regulation of cell cell adhesion 0.5233725747612596 1.211456640023246 0.2257204430132193 1.0 1.0 19 Q9HCM4,Q5JRA6,P42574,Q9Y5A9,P31749,Q9BZE4,Q9Y6D9 7 +Positive regulation of phospholipid metabolic process 0.6046197759996194 1.2113522892956587 0.2257604164784652 1.0 1.0 6 Q99653,P17655,Q9UJZ1 3 +Response to vitamin d 0.6045725644931493 1.2111420201885452 0.2258409792769797 1.0 1.0 6 O15164,P20020,Q8TB36 3 +Positive regulation of stem cell differentiation 0.6753632255059777 1.2110028162696411 0.2258943253489338 1.0 1.0 4 O43809,Q13610 2 +Cellular copper ion homeostasis 0.7400482509047227 1.2106014526131772 0.2260481872781023 1.0 1.0 3 O43819,O60826 2 +Positive regulation of myeloid leukocyte mediated immunity 0.6037432611099645 1.2074485787725115 0.2272594367662084 1.0 1.0 6 Q7Z434,Q9NY93,Q9NR30,Q9H2U1 4 +Negative regulation of anoikis 0.7388419782871055 1.2059218157685987 0.227847638043972 1.0 1.0 3 Q9Y3E5,Q07820 2 +Maintenance of synapse structure 0.6030102813324902 1.2041842703123722 0.2285183642566548 1.0 1.0 6 Q9BRK5 1 +Dendritic cell cytokine production 0.6242333791703721 1.197790627801353 0.2309985367547509 1.0 1.0 5 Q9NY93,Q9NR30,Q9H2U1 3 +Myeloid dendritic cell cytokine production 0.6242333791703721 1.197790627801353 0.2309985367547509 1.0 1.0 5 Q9NY93,Q9NR30,Q9H2U1 3 +Positive regulation of dendritic cell cytokine production 0.6242333791703721 1.197790627801353 0.2309985367547509 1.0 1.0 5 Q9NY93,Q9NR30,Q9H2U1 3 +Regulation of mitochondrial membrane potential 0.5186511399583854 1.193220405839033 0.2327830649674758 1.0 1.0 20 P09874,Q07812,P04179,P31749,P28331,Q9H2U2,Q9BSK2,Q9UJZ1,Q9UII2 9 +Chemokine production 0.5615641572402179 1.1895502125851352 0.234223224254793 1.0 1.0 8 P14174 1 +Import across plasma membrane 0.5220652699054139 1.1893913792604784 0.234285691581066 1.0 1.0 16 P31749,P41440,P08195 3 +Regulation of cardiac muscle cell action potential involved in regulation of contraction 0.7344932921259053 1.189057430839192 0.2344170681616568 1.0 1.0 3 Q9HD47 1 +Adiponectin activated signaling pathway 0.7333780185702239 1.1847339882766408 0.2361226396312972 1.0 1.0 3 Q9UKG1 1 +L amino acid transport 0.5201398068144027 1.1845461457111586 0.236196940808695 1.0 1.0 12 O60831 1 +Myeloid leukocyte migration 0.5104091853199543 1.1823406544081356 0.2370705605166303 1.0 1.0 23 Q07021,O75083,P35613,Q08722,P30046,Q8NE86,O94813,P61011,P39019,Q8N5M9,P14174 11 +Homologous chromosome segregation 0.5171507981870014 1.18169625071944 0.2373262465395167 1.0 1.0 10 Q9BTX1,O94901 2 +Proton transmembrane transport 0.3780035968308606 1.1795455130221308 0.2381810247798053 1.0 1.0 45 O14548,P20674,P05141,P56134,P21283,Q99653,Q00325,Q9UHD1,Q9BSH4,P48047,P03915,P30405,Q9UJZ1,Q9UDW1 14 +Neutrophil mediated immunity 0.5972582053517151 1.178573273347428 0.2385681392699215 1.0 1.0 6 Q8N5M9,P51809,O75083,P78536 4 +Negative regulation of inclusion body assembly 0.6659159747309057 1.172250835042209 0.241096364270922 1.0 1.0 4 P25685 1 +Negative regulation of cell substrate junction organization 0.665761689291102 1.1716183295614857 0.2413503256505431 1.0 1.0 4 Q9P258,O75122,P63167 3 +Golgi organization 0.3562298951757142 1.1685970420306004 0.2425660205716773 1.0 1.0 59 O75396,Q92614,Q96JB2,O75122,P60953,P42858,P61019,Q7RTS9,Q9H9E3,P62820,Q99986 11 +Positive regulation of behavior 0.729191797346196 1.168512400380706 0.2426001402754356 1.0 1.0 3 Q9Y6A4,Q96QK1 2 +Regulation of fibroblast migration 0.5363720208827636 1.1678922716136906 0.2428502219216728 1.0 1.0 9 P05556,Q9P258,P31749,O94776,Q02952,Q9UKG1 6 +Negative regulation of nucleocytoplasmic transport 0.5758519574206118 1.1646602297718556 0.2441565533135437 1.0 1.0 7 Q99653,Q9UHD1 2 +Regulation of nucleotide biosynthetic process 0.5556777184547244 1.161290015452571 0.2455239785537244 1.0 1.0 8 P09874,Q15120 2 +Cardiolipin metabolic process 0.5926764528603995 1.1581827577167243 0.2467894631428211 1.0 1.0 6 P51608,Q9UJZ1 2 +Dna dependent dna replication maintenance of fidelity 0.5162791236467655 1.1566654395548728 0.2474090749076802 1.0 1.0 15 Q86V81,P46100,P54132 3 +Mitochondrial ribosome assembly 0.5921987776737334 1.1560575369978157 0.247657623236273 1.0 1.0 6 Q9NYY8,Q9NUL7 2 +Olfactory lobe development 0.7255729794933705 1.1544987202134214 0.2482957629490649 1.0 1.0 3 Q02218,O94813 2 +Regulation of notch signaling pathway 0.5335683269207911 1.1538600158322 0.2485575641305386 1.0 1.0 9 P31749,Q9Y5A9 2 +Endocrine process 0.5912867704852376 1.1520002907577456 0.2493209538488709 1.0 1.0 6 Q92930,P82094 2 +Regulation of protein kinase a signaling 0.7246778421429615 1.151033781677012 0.2497183380651173 1.0 1.0 3 P14174 1 +Leukocyte migration 0.34528418696782 1.1472952352512178 0.2512596225963945 1.0 1.0 48 P61586,Q9Y624,P39019,Q8N5M9,Q9Y3A5,Q07021,Q08722,Q8NE86,P60953,O94813,P31749,P14174,P78536,O75083,P05556,Q5JRA6,P35613,P30046,P61011 19 +Transcription initiation from rna polymerase iii promoter 0.7225310766382471 1.1427264444530736 0.2531521867043502 1.0 1.0 3 Q12789 1 +Response to immobilization stress 0.722343948375784 1.142002483634594 0.2534529873211064 1.0 1.0 3 P04179 1 +Protein localization to chromosome telomeric region 0.5106055964275141 1.1392452342597117 0.2546008835816065 1.0 1.0 19 O75367,P46100,Q96BK5,Q15554 4 +Maturation of 5 8s rrna 0.4779208499220901 1.1383618076036954 0.2549694349868101 1.0 1.0 30 Q14137,Q13868,Q9Y4W2,O95478,Q9Y2P8,Q9H9Y2,Q96B26,Q99547,Q8IY81,Q06265 10 +Osteoblast differentiation 0.373463722145429 1.1379604818462234 0.2551369841322679 1.0 1.0 45 P22087,Q86V81,P62841,Q9NY93,P35222,O75643,P35998,P41252,Q9UBG0,O76021,Q9NR30,Q9H6W3,Q16539,P31749,Q9P2E9,Q00839,P61604,Q9BZE4,O94874,Q9BQG0,Q13418 21 +Positive regulation of autophagy of mitochondrion 0.6102639199040875 1.1370961499415886 0.2554980932456128 1.0 1.0 5 P42858 1 +Glycoprotein metabolic process 0.3605630396701398 1.135933117405582 0.2559845568246417 1.0 1.0 63 O75340,O43909,Q6ZXV5,P04844,Q16706,Q99653,Q96JB2,Q14165,O95394,Q9BXS4,Q9Y673,O60568,Q9H488,Q13724,P62820 15 +Peptidyl glutamic acid modification 0.6085050811412327 1.1294633236251057 0.2587024329699674 1.0 1.0 5 P09874,Q9Y6A4 2 +Regulation of rho protein signal transduction 0.5099520574430608 1.1260958166624349 0.2601249645587742 1.0 1.0 13 Q9NWH9,P41440 2 +Phagosome lysosome fusion 0.7177322074789143 1.1241697092222878 0.2609410370564635 1.0 1.0 3 Q9NVJ2,Q9BZG1 2 +Regulation of release of cytochrome c from mitochondria 0.508696450327791 1.1238039013216534 0.2610962260695957 1.0 1.0 12 P31749,P30405,Q96A26 3 +Ovarian follicle development 0.5844130281495542 1.1214383348246657 0.2621013261786413 1.0 1.0 6 Q9UI10,Q05086 2 +Positive regulation of insulin secretion involved in cellular response to glucose stimulus 0.606221480785446 1.119556958533172 0.2629026058628056 1.0 1.0 5 P55809 1 +Regulation of protein maturation 0.5071747605317487 1.115746676120088 0.264530584778166 1.0 1.0 12 Q9UMY4 1 +Positive regulation of cell division 0.5085252047219102 1.115699146181398 0.2645509361768485 1.0 1.0 14 Q9Y2S7,P37198,P61586,Q9H8V3,P60953,Q7Z7K6,P08069 7 +Dtmp metabolic process 0.652048418862448 1.1154629599926005 0.2646520825325675 1.0 1.0 4 P34896 1 +Pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.652048418862448 1.1154629599926005 0.2646520825325675 1.0 1.0 4 P34896 1 +Pyrimidine deoxyribonucleoside monophosphate metabolic process 0.652048418862448 1.1154629599926005 0.2646520825325675 1.0 1.0 4 P34896 1 +Negative regulation of vascular associated smooth muscle cell proliferation 0.604225012985004 1.1108999261891033 0.2666114272751163 1.0 1.0 5 P61586,P04179 2 +Neutrophil chemotaxis 0.5048841025341225 1.109770128375112 0.2670980945585486 1.0 1.0 11 Q07021,P35613,Q8NE86,P61011,O94813 5 +Protein dna complex subunit organization 0.3763661534506586 1.10940690479007 0.2672546850232162 1.0 1.0 73 P10412,P50748,O75367,Q12824,P46100,P16403,P16402,O15160,Q9P0M6,Q9GZN1,P17096,Q96T23,Q5SSJ5,Q7Z7K6,Q92522,Q9NPF5,P62805,P07305 18 +Positive regulation of monooxygenase activity 0.5635510768881271 1.1079595629127523 0.2678792799833456 1.0 1.0 7 P31749 1 +Regulation of keratinocyte differentiation 0.5444390902575138 1.1074356893537616 0.2681056027134727 1.0 1.0 8 Q9P0M6,Q13247 2 +Cytoplasmic translation 0.4451295936631055 1.1070750238144913 0.2682614930019908 1.0 1.0 113 P83731,Q7L2H7,Q02878,P62424,P61513,P18077,Q9Y3U8,Q9H2U1,P50914,P62269,P62701,P62280,P62750,Q9NR50,P62857,P62841,P20042,P39019,P08708,P05388,P30050,Q15056,P62277,Q9Y5A9,P61927,Q13347,P46777,P40429,P62241,P62854,P46776,P62081,P62851,P62753,P62266,Q7Z478,Q02543,Q8WU90,P26373,P63173,P61247,P61353,P36578,P16989,P62847,P62910,P83881,P62899,Q00839,P18124,P15880,P84098,P39023,P32969,P60866,P62917,P47914,P62263,P46778,P61313,P62244 61 +Regulation of dna dependent dna replication initiation 0.7128844809275124 1.1054448292703676 0.2689668879095159 1.0 1.0 3 Q9ULV3 1 +Lymphocyte homeostasis 0.5024055974926634 1.1045464236531606 0.2693561771606176 1.0 1.0 10 P42574,P31749,P14174,Q9HCL2 4 +Calcium ion regulated exocytosis 0.5020259526048276 1.1025656663659325 0.270215827074588 1.0 1.0 10 Q9NVJ2,O00186,Q9BRK5,P51809,P16615 5 +Wound healing spreading of epidermal cells 0.5798504010520364 1.1011721224636186 0.2708217522381284 1.0 1.0 6 O75122 1 +Homologous chromosome pairing at meiosis 0.5226146339976097 1.0991481698114651 0.2717034419086501 1.0 1.0 9 Q9BTX1,O94901 2 +Positive regulation of transcription of nucleolar large rrna by rna polymerase i 0.5420462067385141 1.0959906624346254 0.2730828608207458 1.0 1.0 8 Q12824 1 +Regulation of synapse assembly 0.5786296408089364 1.095752951976894 0.2731869028045199 1.0 1.0 6 Q04637,P62330,Q9H2P0,Q96HC4,Q96QK1 5 +Negative regulation of atp dependent activity 0.560857913111512 1.0955661542072332 0.2732686801541202 1.0 1.0 7 P30405 1 +Sugar mediated signaling pathway 0.6464555052790361 1.0926045174415095 0.2745674784318916 1.0 1.0 4 P17480,Q12824,P51532 3 +Deoxyribonucleotide biosynthetic process 0.5212262160750338 1.0922279045544545 0.2747329401561305 1.0 1.0 9 P34896,Q7LG56 2 +Negative regulation of peptidyl serine phosphorylation 0.709437144762019 1.0921431606166028 0.2747701810793266 1.0 1.0 3 Q13610 1 +Negative regulation of mononuclear cell migration 0.6461521257357898 1.0913654753308697 0.2751120976739916 1.0 1.0 4 P31749,Q5JRA6 2 +Phagosome maturation 0.645942803053164 1.090510629577853 0.275488273547541 1.0 1.0 4 Q9BZG1 1 +Phagolysosome assembly 0.645942803053164 1.090510629577853 0.275488273547541 1.0 1.0 4 Q9BZG1 1 +Granulocyte migration 0.5033105189119013 1.0887313856499965 0.2762723570283927 1.0 1.0 17 Q07021,O75083,P35613,Q8NE86,O94813,P61011,Q8N5M9 7 +Regulation of small gtpase mediated signal transduction 0.3769247872109595 1.0881659419321847 0.276521857091256 1.0 1.0 44 Q5VZ89,Q9NWH9,P62330,Q07960,Q9Y624,O75962,P41440 7 +Xenobiotic transport 0.6451836606074461 1.0874107795217527 0.2768553093597361 1.0 1.0 4 P41440 1 +Odontogenesis of dentin containing tooth 0.576636397576535 1.0869077525362254 0.2770775797983065 1.0 1.0 6 Q07812,Q92769,P35613 3 +Transmembrane receptor protein tyrosine phosphatase signaling pathway 0.9728670485378342 1.0854517980779712 0.2777216014593424 1.0 1.0 2 P10586 1 +3 phosphoadenosine 5 phosphosulfate metabolic process 0.6443557698765042 1.0840309056551083 0.2783510960006601 1.0 1.0 4 Q8TB61 1 +Actin polymerization dependent cell motility 0.6438852753107661 1.0821104370040562 0.2792034587162231 1.0 1.0 4 Q8N8S7 1 +Cleavage involved in rrna processing 0.4955850394276217 1.0818211366749269 0.2793320127118697 1.0 1.0 22 Q14137,Q12788,Q13868,Q2NL82,Q9Y2P8,Q96B26,Q06265 7 +Phosphate ion transport 0.7062726176115809 1.0799438856402463 0.2801671690517828 1.0 1.0 3 Q00325,Q9UBX3 2 +Phosphate ion transmembrane transport 0.7062726176115809 1.0799438856402463 0.2801671690517828 1.0 1.0 3 Q00325,Q9UBX3 2 +Lung epithelium development 0.5739417958783541 1.074956854462109 0.2823940455775859 1.0 1.0 6 Q13247 1 +Positive regulation of peptidyl tyrosine phosphorylation 0.4997453975419396 1.0672728023343565 0.2858486658714811 1.0 1.0 16 P14174,O14641 2 +Leukocyte homeostasis 0.4988898770899688 1.0672121649266937 0.285876040520826 1.0 1.0 13 P31749,P14174,Q9HCL2,P78536 4 +Protein kinase c signaling 0.640082314747437 1.0665966626990584 0.2861540081597811 1.0 1.0 4 P41440 1 +Negative regulation of blood vessel endothelial cell migration 0.5939531972579668 1.0664239376480715 0.2862320455104576 1.0 1.0 5 P51608,P61586,P14923 3 +Monocarboxylic acid transport 0.4948915993522851 1.0654070909332052 0.2866917493123995 1.0 1.0 10 O15439,P14174 2 +Type b pancreatic cell apoptotic process 0.5930567154381811 1.0625480621208012 0.2879869511494499 1.0 1.0 5 Q13247 1 +Proline metabolic process 0.5929390464695186 1.0620394051428308 0.288217796621899 1.0 1.0 5 P32322,P54886,P30038,Q96C36 4 +Macrophage activation 0.5348996636791638 1.06186406530693 0.2882974005877465 1.0 1.0 8 Q92614 1 +Nuclear migration 0.4978575584354264 1.0617346591190635 0.2883561602677371 1.0 1.0 13 Q9UH99,P60953,Q9Y613,O94901 4 +Cardiac muscle cell contraction 0.4923485440275279 1.0521938778451758 0.292710607765092 1.0 1.0 10 Q14126,Q9HD47,Q99996,P15924,P14923,P16615 6 +Carboxylic acid transport 0.4498186315453027 1.0513236871002083 0.2931099516118727 1.0 1.0 33 O60831,O15439,P14174,P08195,P41440 5 +Nadh dehydrogenase complex assembly 0.4599004154546655 1.0512263393621075 0.2931546487094123 1.0 1.0 31 O95139,P03915,O75438,O43676,Q86Y39,Q8IUX1,O95168,P28331,Q96CU9 9 +Regulation of tumor necrosis factor mediated signaling pathway 0.5508297985238193 1.0495038501989415 0.2939462841277771 1.0 1.0 7 Q8TCT8 1 +Neural plate morphogenesis 0.96141091347603 1.046916934731127 0.2951378906178545 1.0 1.0 2 O14641 1 +Positive regulation of epidermis development 0.56695981588124 1.0440309332737072 0.2964710782247419 1.0 1.0 6 Q9P0M6 1 +Positive regulation of epidermal cell differentiation 0.56695981588124 1.0440309332737072 0.2964710782247419 1.0 1.0 6 Q9P0M6 1 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4934477656096379 1.0433328399510795 0.2967941664738025 1.0 1.0 12 P14174 1 +Regulation of protein autophosphorylation 0.5309470864204928 1.043029324774592 0.2969347113549512 1.0 1.0 8 Q99653,O60934 2 +Negative regulation of vascular associated smooth muscle cell migration 0.6966283757666538 1.0428389073125204 0.2970229082441906 1.0 1.0 3 P61586 1 +Vesicle cytoskeletal trafficking 0.4949446794896442 1.0428241137420882 0.2970297610112693 1.0 1.0 17 O00159,P62820,P42858,Q9Y496 4 +Cytokine mediated signaling pathway 0.3418632862839477 1.0420276885757542 0.2973988419409978 1.0 1.0 58 Q96T37,Q8TCT8,Q9Y5A9,P31749,Q8N5M9,Q8WU90,Q86Y07 7 +Prostaglandin transport 0.9593005728067522 1.039838975614197 0.2984147178911371 1.0 1.0 2 P14174 1 +Guanine nucleotide transport 0.9593005728067509 1.0398389756141924 0.2984147178911394 1.0 1.0 2 P41440 1 +Guanine nucleotide transmembrane transport 0.9593005728067509 1.0398389756141924 0.2984147178911394 1.0 1.0 2 P41440 1 +Negative regulation of oxidative stress induced cell death 0.4927080792210807 1.0394464329140092 0.2985971586466882 1.0 1.0 12 P31749,Q9NWH9 2 +Positive regulation of endothelial cell proliferation 0.4925890985706334 1.0388214597539056 0.2988877789671056 1.0 1.0 12 P31749,P78536 2 +Positive regulation of oxidoreductase activity 0.4890242925672718 1.0349498557894357 0.3006923296703192 1.0 1.0 10 P31749 1 +Telomere maintenance via semi conservative replication 0.5648835342178173 1.0348467196784323 0.3007405003724348 1.0 1.0 6 P54132 1 +Deoxyribonucleoside monophosphate biosynthetic process 0.5643603986905004 1.032533663960224 0.3018221858244836 1.0 1.0 6 P34896 1 +Hydrogen peroxide catabolic process 0.6314457079026017 1.0314316810156503 0.3023384306109065 1.0 1.0 4 Q13162 1 +Ncrna catabolic process 0.4694373483006298 1.0304162011736897 0.3028146711659705 1.0 1.0 28 Q9Y6V7,Q8TCS8,Q13868,Q99575,Q9BRJ7,Q5RKV6,Q96DE0,Q96B26,Q06265 9 +Maintenance of protein location in nucleus 0.487950220854467 1.0293854614767075 0.30329857817819 1.0 1.0 10 Q9ULV3 1 +Positive regulation of epithelial cell proliferation 0.4689197945027585 1.0271918580986792 0.3043301311895523 1.0 1.0 28 Q13247,P11047,P31749,P60953,Q8TAF3,P78536 6 +Positive regulation of nitric oxide synthase activity 0.5847047238592553 1.0264918892607644 0.3046597847705345 1.0 1.0 5 P31749 1 +Regulation of cardiac muscle cell membrane repolarization 0.6302290279585956 1.0264860971942336 0.3046625135596474 1.0 1.0 4 Q99996 1 +Cellular response to ph 0.6300079214418666 1.0255875743903886 0.3050860268690401 1.0 1.0 4 Q99653,Q9UHD1 2 +Regulation of oligodendrocyte differentiation 0.5449437952488527 1.0225416873272486 0.3065245926887789 1.0 1.0 7 Q15382 1 +Regulation of peptide transport 0.4780249303557481 1.022039649500682 0.3067621348220637 1.0 1.0 25 Q92930,P55809,Q9BRT2,Q8NE86,Q8N5M9 5 +Positive regulation of small molecule metabolic process 0.4913214148965851 1.021582393911326 0.3069785940652949 1.0 1.0 16 Q92604 1 +Oligosaccharide lipid intermediate biosynthetic process 0.689987937273836 1.0173635925642674 0.308980494869401 1.0 1.0 3 O75340,Q9BT22 2 +Photoperiodism 0.5822429528677886 1.015884326439856 0.3096844734249238 1.0 1.0 5 P62140,Q13330 2 +Regulation of cell cell adhesion 0.3509130557257427 1.0152550233189974 0.3099842779908262 1.0 1.0 46 Q9HCM4,Q5JRA6,P42574,Q9Y5A9,Q16539,P61586,Q9Y624,P31749,Q9HCL2,P04439,Q9BZE4,P41440,Q9Y6D9 13 +Trna methylation 0.4899869298446759 1.0146598798940762 0.3102679849184349 1.0 1.0 15 Q9NXH9,Q8TEA1,Q969Y2 3 +Endoderm development 0.487847046639891 1.013951837511291 0.3106057343909409 1.0 1.0 12 Q9HCM4,P11047 2 +Heat acclimation 0.6890201370579964 1.0136562283966457 0.3107468172487513 1.0 1.0 3 P17066 1 +Leukocyte chemotaxis 0.4736078075956635 1.0135255485109391 0.3108091992077475 1.0 1.0 26 Q07021,P35613,P30046,Q8NE86,P39019,O94813,P14174,P78536,Q9Y3A5 9 +Mitochondrial rna 3 end processing 0.6262709369153974 1.0104127127802056 0.3122975996545167 1.0 1.0 4 Q8TCS8 1 +Macropinocytosis 0.6872977781658827 1.007062011950458 0.313904975033388 1.0 1.0 3 Q9BZG1 1 +Negative regulation of telomere maintenance via telomerase 0.5036292197103056 1.004892401759561 0.314948663556291 1.0 1.0 9 Q15554,Q96BK5 2 +Spliceosomal complex assembly 0.3915636632554358 1.0047456971379871 0.3150193178706926 1.0 1.0 41 Q13247,P09234,Q92879,O95391,Q15428,P62304,O94906,Q9BZJ0,O75475,Q9UKA9,Q99590,Q9BUQ8,Q9UMS4,P62314,Q9ULR0,O75643,Q15637,Q86UA1 18 +Negative regulation of type b pancreatic cell apoptotic process 0.6247117324501021 1.0040877730105553 0.3153363083613461 1.0 1.0 4 Q13247 1 +Positive regulation of sodium ion transport 0.4857731942230939 1.003100716231029 0.3158122691665777 1.0 1.0 12 Q99653,P31749,P54709 3 +Positive regulation of embryonic development 0.5406283192914291 1.0028147795661368 0.3159502364886046 1.0 1.0 7 Q9Y4C8 1 +Regulation of endoplasmic reticulum tubular network organization 0.5787349473750838 1.0007862169110768 0.316930174482759 1.0 1.0 5 Q6DD88,Q9H2M9,P57088 3 +Positive regulation of t cell migration 0.6237595465505258 1.000227191412069 0.3172005730112941 1.0 1.0 4 P61586,P78536 2 +Positive regulation of lymphocyte migration 0.6237595465505258 1.000227191412069 0.3172005730112941 1.0 1.0 4 P61586,P78536 2 +Positive regulation of fibroblast migration 0.6232233789998212 0.9980540042056448 0.3182531722057258 1.0 1.0 4 P31749 1 +Positive regulation of epithelial cell proliferation involved in lung morphogenesis 0.9460355743141388 0.9955108074634031 0.3194878905873193 1.0 1.0 2 Q13247 1 +Regulation of epithelial cell proliferation involved in lung morphogenesis 0.9460355743141388 0.9955108074634031 0.3194878905873193 1.0 1.0 2 Q13247 1 +Regulation of actin filament bundle assembly 0.4636464086477873 0.9944391591507508 0.3200091116516108 1.0 1.0 28 P35080,Q9NWH9,Q9Y624,P60953,Q9Y613 5 +Morphogenesis of an endothelium 0.6839565741857752 0.99428365207546 0.3200847923063183 1.0 1.0 3 P61586,P67870 2 +Exocrine system development 0.6838067895760399 0.9937112416805808 0.3203634681881588 1.0 1.0 3 P60953 1 +L serine biosynthetic process 0.6823943418246685 0.988315387552996 0.3229982116921581 1.0 1.0 3 P78330 1 +Regulation of protein secretion 0.3289848282897927 0.9851831766552936 0.3245341027034532 1.0 1.0 48 Q92614,P62330,Q9BRT2,Q8NE86,Q8N5M9 5 +Endoplasmic reticulum tubular network organization 0.4820077872977205 0.9834408499906784 0.325390513562237 1.0 1.0 12 Q9H6H4,Q6NUK4 2 +Cell substrate junction organization 0.461842006904536 0.9832761742454856 0.325471533075115 1.0 1.0 28 Q92930,Q9HCM4,P11047,Q9Y2S7,P62330 5 +Carbohydrate phosphorylation 0.5361116346368462 0.982209725651528 0.3259965372049698 1.0 1.0 7 P51570,P52789,Q9Y223,Q3LXA3 4 +Hypothalamus development 0.6179814068639201 0.9768339295729358 0.3286513755447013 1.0 1.0 4 O14949 1 +Negative regulation of muscle cell apoptotic process 0.5730670569999141 0.9764396242963026 0.3288466535815644 1.0 1.0 5 Q96QC0 1 +Negative regulation of leukocyte apoptotic process 0.6178451111814252 0.976282857500406 0.328924312572866 1.0 1.0 4 P14174 1 +Negative regulation of lymphocyte apoptotic process 0.6178451111814252 0.976282857500406 0.328924312572866 1.0 1.0 4 P14174 1 +Mrna splice site selection 0.476969606899214 0.9747539897447 0.3296823048951749 1.0 1.0 22 Q13247,P09234,O95391,Q15428,O75475,Q9UKA9,Q92879,Q9ULR0,Q15637,Q86UA1 10 +Positive regulation of tor signaling 0.4974909664596664 0.9746252140525514 0.3297462017926635 1.0 1.0 9 Q6IAA8,Q8N122,Q15382 3 +Neuron projection guidance 0.4724531431183715 0.9734965397998786 0.3303065791134028 1.0 1.0 24 Q8N8S7,Q13740,O75962,P11047 4 +Methylglyoxal metabolic process 0.6169730548745913 0.9727577818869014 0.3306736998184376 1.0 1.0 4 Q04760,Q16775 2 +Regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.480562573370761 0.9705208031465714 0.3317869606080044 1.0 1.0 13 P09874,P31749,Q07820,P04179 4 +Negative regulation of hippo signaling 0.9384986433524258 0.9704593354846712 0.3318175849252252 1.0 1.0 2 P46734 1 +Response to dietary excess 0.9384986433524248 0.9704593354846686 0.3318175849252265 1.0 1.0 2 Q9BZK7 1 +Synaptic membrane adhesion 0.9384986433524234 0.9704593354846636 0.3318175849252289 1.0 1.0 2 P10586 1 +Positive regulation of mononuclear cell migration 0.4964404848116767 0.9694575209286928 0.3323169648404867 1.0 1.0 9 Q07021,Q9H4A3,Q08722,P61586,Q8NHP6,P78536 6 +Mitochondrial electron transport nadh to ubiquinone 0.4689134560829037 0.9679341792479278 0.3330772430955275 1.0 1.0 25 O95139,O75438,O43676,O95168,O75380,P28331,P03915 7 +Regulation of nuclease activity 0.4772703754849872 0.9657847377677724 0.334151907101643 1.0 1.0 11 P31749 1 +Entrainment of circadian clock 0.549002940237325 0.964834083554222 0.3346279214079573 1.0 1.0 6 P62140,P62136,Q13330 3 +Positive regulation of blood pressure 0.6145571132482944 0.9629995861867334 0.3355477309360597 1.0 1.0 4 P61586,P11766 2 +Negative regulation of calcium mediated signaling 0.6141536298264288 0.9613710027852764 0.3363656588482109 1.0 1.0 4 Q99653 1 +Negative regulation of calcineurin mediated signaling 0.6141536298264288 0.9613710027852764 0.3363656588482109 1.0 1.0 4 Q99653 1 +Water soluble vitamin metabolic process 0.4798584430771841 0.9607628608557012 0.3366714162900783 1.0 1.0 17 Q96RQ3,P41440 2 +Taxis 0.3537469200547667 0.9598013830261236 0.337155186138629 1.0 1.0 69 Q8N8S7,P11047,Q9NWH9,Q16539,P35613,Q13740,Q8NE86,P51153,O75962,P14174 10 +Regulation of dna dependent dna replication 0.4759905167970509 0.9596753068881838 0.3372186547703837 1.0 1.0 21 O60934,P46100,P54132,Q9ULV3 4 +Constitutive heterochromatin assembly 0.6135815099152353 0.9590623112356772 0.3375273554811515 1.0 1.0 4 Q7Z7K6 1 +Regulation of sodium proton antiporter activity 0.6128205078856985 0.955992447546496 0.3390760501597061 1.0 1.0 4 Q99653 1 +Regulation of mitochondrial dna replication 0.6735534865416155 0.9546236547065337 0.3397680504644074 1.0 1.0 3 Q9UJZ1 1 +Seminiferous tubule development 0.9318661441061198 0.9485028487601735 0.3428735232423019 1.0 1.0 2 Q8TAF3 1 +Isopentenyl diphosphate biosynthetic process 0.6706875753920309 0.9437344460828532 0.3453053669104393 1.0 1.0 3 Q03426,Q15126 2 +Hormone transport 0.4111161150109673 0.9430060294092334 0.3456778189141904 1.0 1.0 37 Q92930,P55809,Q9BRT2,P82094,Q8NE86,Q8N5M9,P62820 7 +Regulation of dna duplex unwinding 0.6085549488282953 0.9388077331155746 0.3478294678221831 1.0 1.0 4 P11388,Q04837 2 +Positive regulation of smooth muscle cell proliferation 0.4718836354202339 0.9380217414917964 0.3482332371201795 1.0 1.0 11 Q5SW96,P31749,O95140 3 +Regulation of synaptic vesicle exocytosis 0.4713163842181429 0.9351057791220816 0.3497337885712184 1.0 1.0 11 P35080 1 +Regulation of calcineurin mediated signaling 0.5419410771186836 0.933860579329991 0.3503758156647985 1.0 1.0 6 Q99653 1 +Autophagy of mitochondrion 0.4157814918073995 0.9329580365618224 0.350841635179941 1.0 1.0 36 Q9Y4P1,O95140,P42858,P53365 4 +G1 to g0 transition 0.5251607791306682 0.9324552692973432 0.3511012931237003 1.0 1.0 7 P52758 1 +Peptidyl cysteine modification 0.5071724261104193 0.9305288674849296 0.3520973248254064 1.0 1.0 8 Q96JJ7,P30048,P04406 3 +Neurotransmitter receptor transport endosome to postsynaptic membrane 0.6652453200512766 0.9231039081507468 0.3559530581772723 1.0 1.0 3 P61006 1 +Neurotransmitter receptor transport to plasma membrane 0.6652453200512766 0.9231039081507468 0.3559530581772723 1.0 1.0 3 P61006 1 +Stress fiber assembly 0.4443151784651264 0.9225692390972338 0.3562317322605524 1.0 1.0 30 P35080,Q9NWH9,Q9Y624,P60953,Q9Y613 5 +Multicellular organismal response to stress 0.5053290080191468 0.9218751760955538 0.3565936889206487 1.0 1.0 8 P17655 1 +Cell cell adhesion via plasma membrane adhesion molecules 0.4723970033772172 0.921133055991643 0.3569809638378247 1.0 1.0 15 Q16539,Q13740,P10586,P35613 4 +Mammary gland epithelium development 0.5049461055381723 0.9200791547059424 0.35753139665418 1.0 1.0 8 P31749 1 +Vitamin d receptor signaling pathway 0.6641732315312378 0.9190475205523928 0.358070716960839 1.0 1.0 3 O15164 1 +Regulation of vitamin d receptor signaling pathway 0.6641732315312378 0.9190475205523928 0.358070716960839 1.0 1.0 3 O15164 1 +Outflow tract morphogenesis 0.537985568266901 0.916563127107235 0.3593716137232468 1.0 1.0 6 O14641 1 +Response to electrical stimulus 0.537539590134774 0.9146153554830706 0.3603935945741285 1.0 1.0 6 Q02952,P04179 2 +Regulation of hormone secretion 0.4429466812483941 0.9139686040052852 0.3607333431422064 1.0 1.0 30 Q92930,P55809,Q9BRT2,P82094,Q8NE86,Q8N5M9 6 +Cellular response to nutrient 0.5204956898981499 0.9113593944583972 0.3621060411227113 1.0 1.0 7 O15164,P20020,Q8TB36 3 +Columnar cuboidal epithelial cell differentiation 0.4699539420938464 0.9109760142135732 0.3623080118265953 1.0 1.0 14 Q15382 1 +Regulation of cardiac conduction 0.6619420989143622 0.9106141891332582 0.3624986916452526 1.0 1.0 3 P20020,P16615 2 +Cell migration involved in sprouting angiogenesis 0.5024501785118772 0.9083845997533552 0.3636750593459421 1.0 1.0 8 P31749,P61586,O94813,Q5JRA6 4 +Fibroblast migration 0.4701774412160919 0.9082876770291588 0.3637262514539845 1.0 1.0 16 Q9Y2Q5,P05556,Q5SNT2,Q9P258,P31749,Q9UKG1,O94776,Q02952,Q13418 9 +Mitochondrial translational elongation 0.6003960266347469 0.906051860298172 0.3649084036887855 1.0 1.0 4 Q96RP9 1 +Granulocyte chemotaxis 0.469000147855483 0.9059983252078858 0.3649367389000368 1.0 1.0 14 Q07021,P35613,Q8NE86,P61011,O94813 5 +Positive regulation of protein sumoylation 0.60030165912519 0.905673936272538 0.3651084618311406 1.0 1.0 4 Q9H0E2,Q9UBT2,Q9BVP2 3 +Oligodendrocyte differentiation 0.4683773931431908 0.9046437987436292 0.3656541239461321 1.0 1.0 19 Q9UI10 1 +Smooth muscle cell proliferation 0.4642523727807515 0.9027548785394496 0.3666560034281843 1.0 1.0 22 O95140,Q9Y2S7,Q5SW96,P04179,P61586,P31749,Q15637,P08069,Q5VZE5 9 +Negative regulation of telomere maintenance via telomere lengthening 0.463095321369665 0.9018287798197376 0.3671478290399033 1.0 1.0 10 Q15554,Q9H0A0,Q96BK5 3 +Sulfate transport 0.6591584402183339 0.9001088528683966 0.3680623252457087 1.0 1.0 3 Q9UBX3 1 +Regulation of heart rate by cardiac conduction 0.5550376636295598 0.8994607257874688 0.3684073061619082 1.0 1.0 5 Q99996,P14923,Q14126 3 +Protein localization to nucleolus 0.4642986783536115 0.8991610086233451 0.3685669057130156 1.0 1.0 11 Q13895,Q9NZM5,Q9H7B2,Q96BK5 4 +Synapse organization 0.3418759626156729 0.8981198299914896 0.3691216681537237 1.0 1.0 66 P11047,P35080,P62330,P10586,Q9BRK5,P60953,O15020 7 +Cytochrome complex assembly 0.4664128945301528 0.8968617742565028 0.3697926798079729 1.0 1.0 13 O75880,P53701,Q9BSH4,Q69YU5,O43819,Q9BRT2,Q9BSK2 7 +Positive regulation of jnk cascade 0.5542875116525368 0.8962756695830547 0.3701055502886796 1.0 1.0 5 P60953 1 +Rna 5 end processing 0.4667412898021867 0.8942304362371161 0.3711986107089484 1.0 1.0 14 Q99575,Q8TCS8,Q12788,Q8N5L8,Q9ULW3,P78346 6 +Organic acid transport 0.3542928119323424 0.8927434994781781 0.3719945497204324 1.0 1.0 44 O43808,O60831,O15439,P14174,P31749,P08195,P41440 7 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.5533587211683156 0.8923343354977935 0.3722137556908587 1.0 1.0 5 Q9P0I2 1 +Positive regulation of leukocyte migration 0.4668990167912836 0.8922298031449473 0.3722697708090359 1.0 1.0 15 Q07021,Q5JRA6,Q08722,P61586,Q8NE86,Q8NHP6,P78536 7 +Glial cell differentiation 0.3766780844036332 0.8872651187308151 0.3749361805323845 1.0 1.0 41 Q9UI10,P11047,Q15382 3 +Regulation of lymphocyte apoptotic process 0.5312072950678524 0.8870177461254639 0.3750693462580119 1.0 1.0 6 P14174 1 +Maintenance of protein localization in organelle 0.4659687164034999 0.8860266667249276 0.3756031575977163 1.0 1.0 16 P31749,Q9ULV3 2 +Regulation of microtubule nucleation 0.5146498117970015 0.8850195992135708 0.3761460607575906 1.0 1.0 7 Q9HD47 1 +Histone methylation 0.3164190477656614 0.8823926888197134 0.3775644880401256 1.0 1.0 53 Q15022,P10412,O75367,Q12824,P46100,P16403,P16402,P22087,Q13610,Q15291,P51608,Q96L73,Q9Y3Y2,Q6UXN9 14 +Response to carbohydrate 0.3760072725362824 0.8820548053657309 0.3777471706549047 1.0 1.0 41 P55809,Q12824,P42574,O95563,P04179,Q9UI10,Q96ST3,Q9HCL2,Q8N5M9,P46734 10 +Folic acid containing compound metabolic process 0.4643807304737537 0.8819648018437644 0.3777958418219831 1.0 1.0 14 P41440 1 +Copii coated vesicle cargo loading 0.5130217774061335 0.8777044796331427 0.3801041128526523 1.0 1.0 7 P62820,Q5JRA6 2 +Regulation of steroid hormone biosynthetic process 0.6530923629888523 0.8772823909280185 0.3803332743021603 1.0 1.0 3 P08069 1 +Regulation of transcription regulatory region dna binding 0.4597411378024527 0.8759552854598518 0.3810543425907009 1.0 1.0 11 Q96L73,Q96ST3,Q00403,P07305 4 +Mitotic recombination 0.4772126807089186 0.8756118970789938 0.3812410555217282 1.0 1.0 9 Q15554 1 +L proline biosynthetic process 0.5927601809954766 0.8755467237045527 0.3812764990295845 1.0 1.0 4 P32322,P54886,Q96C36 3 +Positive regulation of cytokine production 0.3376609302973255 0.8752725014153911 0.3814256526379509 1.0 1.0 65 Q9H2U1,P04406,Q9NY93,Q99584,P41440,Q9UJZ1,O75787,Q06124,Q9NRA0,Q9NUD5,Q9H6R0,Q9NR30,Q16539,P82094,Q02952,P04439,Q9BY67,P14174,P78536,Q9UKG1,P30046,P62820 22 +Positive regulation of epithelial cell differentiation 0.5123750471511788 0.8748011480952875 0.3816821124270002 1.0 1.0 7 Q9P0M6 1 +Regulation of epidermis development 0.4764143100200726 0.8717497642022728 0.3833449055078266 1.0 1.0 9 Q9P0M6,Q13247 2 +Protein localization to cell surface 0.4623071282131807 0.8717193794551406 0.3833614853695368 1.0 1.0 19 P31749,Q9UJY5,P62330 3 +Alternative mrna splicing via spliceosome 0.3516317695739335 0.870377411045577 0.384094187136875 1.0 1.0 44 Q96T37,O95391,P31483 3 +Regulation of fatty acid metabolic process 0.4626445242784396 0.8699893223775595 0.3843062394362291 1.0 1.0 15 P31749,Q15120,Q92604 3 +Regulation of cyclase activity 0.493750736061306 0.8678079423824614 0.385499481330505 1.0 1.0 8 Q99996,Q16539 2 +Regulation of actomyosin structure organization 0.4427794398555734 0.8669574494732345 0.3859653241797702 1.0 1.0 28 P35080,Q9NWH9,Q9Y624,P60953,Q9Y613 5 +Response to ethanol 0.4604730037679185 0.8618232202530653 0.3887848050321225 1.0 1.0 19 P55809,P00505,P61160,P04179,P49411,P61586,Q9BRK5,O00487,Q9NPF5,P08069 10 +Nucleosome assembly 0.4213230156808906 0.8614135041730102 0.3890103410738954 1.0 1.0 33 P10412,O75367,P46100,P16403,P16402,Q9P0M6,Q96T23,Q5SSJ5,Q92522,P62805,P07305 11 +Sprouting angiogenesis 0.460780549078406 0.8602820930502958 0.3896335613821899 1.0 1.0 15 P31749,Q9Y6I3 2 +Negative regulation of dna biosynthetic process 0.4580135124518228 0.8597069382065384 0.3899506092161751 1.0 1.0 12 Q15554,Q96BK5 2 +Snorna localization 0.5871512434632028 0.853242245446162 0.3935249805418117 1.0 1.0 4 Q8WWY3,P22087 2 +Regulation of epithelial cell migration 0.3648826717561556 0.8523040225130766 0.3940453740217586 1.0 1.0 42 Q9HCM4,P35080,Q9NWH9,P62330,Q16539,P31749,O75122,P46734,P78536 9 +Ether biosynthetic process 0.5431909282971232 0.8493568734533756 0.3956827428893437 1.0 1.0 5 O00116,Q8WVX9 2 +Vascular associated smooth muscle cell migration 0.5860497138674889 0.8488728919578946 0.395952024382689 1.0 1.0 4 P61586 1 +Regulation of protein glycosylation 0.5858318016576571 0.848008957334566 0.3964329822805466 1.0 1.0 4 Q99653,Q9BXS4 2 +Mda 5 signaling pathway 0.6443200629767327 0.8444465200980811 0.3984199361198679 1.0 1.0 3 Q3LXA3 1 +Regulation of mda 5 signaling pathway 0.6443200629767327 0.8444465200980811 0.3984199361198679 1.0 1.0 3 Q3LXA3 1 +Negative regulation of lymphocyte migration 0.6439622195066236 0.8431117181821777 0.3991659656673085 1.0 1.0 3 P31749 1 +Nucleus localization 0.4561759945248826 0.8396057935018382 0.4011294498177862 1.0 1.0 14 Q9UH99,P60953,Q9Y613,O94901 4 +Cellular ketone metabolic process 0.4127868921950843 0.8379223579889462 0.4020743109413038 1.0 1.0 34 P55809,P00505,Q92604,Q15120,Q04760,Q16775,P31749,O75477,P22570,Q8NI60 10 +Positive regulation of signaling receptor activity 0.519750756728055 0.8373945425415165 0.4023708323722168 1.0 1.0 6 P05556,P78536 2 +Protein destabilization 0.4534576078512329 0.8365765411435113 0.4028306363604035 1.0 1.0 12 Q9BUN8,P42858,Q96AB3 3 +Positive regulation of protein kinase a signaling 0.897497738920706 0.8362873727493624 0.4029932551315482 1.0 1.0 2 P14174 1 +Pigment cell differentiation 0.5185632357380041 0.8322759684638269 0.4052531919727027 1.0 1.0 6 Q9BXS5,P29992,Q86YV9,P04179,O14617 5 +Positive regulation of mitochondrion organization 0.451189346264189 0.8300455614481123 0.4065130242032571 1.0 1.0 22 P05141,Q96A26,Q8NE86,Q9NX47,P42858,P30405,Q9UII2 7 +Negative regulation of cell adhesion 0.4247675758256888 0.8260955068852682 0.4087499162659864 1.0 1.0 31 Q9HCM4,Q5JRA6,P42574,Q9Y5A9,P42771,P61586,P31749,O75122,Q9BZE4,Q9Y6D9 10 +Positive regulation of protein secretion 0.4390176936619883 0.8256611395037159 0.4089963422842748 1.0 1.0 27 P55809,Q8NE86,P62330,Q92614 4 +Regulation of leukocyte chemotaxis 0.4542946035122184 0.8248973621725993 0.4094298640542027 1.0 1.0 16 Q07021,P30046,Q8NE86,O94813,P14174,P78536 6 +Positive regulation of anoikis 0.639041127838113 0.8247945821348754 0.4094882230990482 1.0 1.0 3 Q9Y3E5 1 +Negative regulation of dna repair 0.4511013961888923 0.824667541677743 0.4095603641743213 1.0 1.0 12 Q9BRJ7 1 +Positive regulation of granulocyte chemotaxis 0.5372603760624636 0.8244463157154492 0.4096860073832942 1.0 1.0 5 Q8NE86,Q07021 2 +Positive regulation of neutrophil migration 0.5372603760624636 0.8244463157154492 0.4096860073832942 1.0 1.0 5 Q8NE86,Q07021 2 +Endocrine system development 0.4517823021379841 0.8218977676342726 0.4111350836153824 1.0 1.0 13 Q15382 1 +Negative regulation of leukocyte cell cell adhesion 0.4515576694707529 0.8207578652043883 0.4117842031539696 1.0 1.0 13 P42574,P31749,Q9Y6D9 3 +Platelet morphogenesis 0.4997699497311334 0.8185304320162283 0.4130543724558539 1.0 1.0 7 P42574,Q06124,O75083 3 +Regulation of calcium mediated signaling 0.4648282467965039 0.8160699262243419 0.4144601431757562 1.0 1.0 9 P42858 1 +Kinetochore assembly 0.635705669481317 0.8124224085118587 0.4165492923876814 1.0 1.0 3 P50748,Q7Z3K3 2 +Positive regulation of vascular associated smooth muscle cell apoptotic process 0.8899608079589947 0.812082894674968 0.4167440676053107 1.0 1.0 2 O95140 1 +Vasodilation 0.8899608079589922 0.812082894674961 0.4167440676053147 1.0 1.0 2 O60568 1 +Positive regulation of chemotaxis 0.4517983471016023 0.8115564556465286 0.4170461858774668 1.0 1.0 17 Q8NE86,Q07021,Q9NWH9,P78536 4 +Regulation of fat cell differentiation 0.4510324014694479 0.807994665817658 0.4190936528693596 1.0 1.0 16 P31749,O75962,Q16539,P04179 4 +Positive regulation of histone acetylation 0.4443026362680039 0.8074198498600459 0.419424634557574 1.0 1.0 10 Q969T9,Q49A26 2 +Ventricular cardiac muscle cell membrane repolarization 0.632582127193946 0.8008691966802135 0.4232073744079425 1.0 1.0 3 Q99996 1 +Ruffle organization 0.4495053992871102 0.8006310121648151 0.4233452916665077 1.0 1.0 18 P35080,P53365 2 +Vesicle docking 0.4494977726828398 0.7995756159396693 0.4239567198581269 1.0 1.0 17 Q92930,Q7Z6M1 2 +Sulfur compound transport 0.4952681027428135 0.7985938009313265 0.4245259833212369 1.0 1.0 7 O15439 1 +Response to axon injury 0.448581049230341 0.7957858705374689 0.426156505645562 1.0 1.0 18 P11047 1 +Positive regulation of protein import 0.4480894202812092 0.7957070004017621 0.4262023570165811 1.0 1.0 19 Q9NW64,Q9NPF5,Q16539 3 +Negative regulation of intracellular transport 0.4485288153589449 0.7955123010118862 0.4263155583638467 1.0 1.0 18 Q9UMY4,Q07960 2 +Tissue migration 0.310938895353832 0.7944918429944021 0.4269091557725106 1.0 1.0 55 Q9HCM4,P35080,Q9NWH9,P62330,Q16539,P31749,O75122,P51153,P46734,P78536 10 +Hepatocyte apoptotic process 0.5720214330370259 0.7935747669318148 0.4274430269695037 1.0 1.0 4 P62330 1 +Protein localization to postsynapse 0.5713053551079974 0.7907705461846708 0.4290779005135903 1.0 1.0 4 P61006 1 +Response to bacterium 0.3231292870348953 0.7899564069393644 0.4295532274425844 1.0 1.0 62 P81605,P17655,Q16539,P04179,P82094,P62820,P31749,Q02952,P14174,P46734,P78536 11 +Macrophage apoptotic process 0.6294772319238024 0.7894176716528517 0.4298679307026871 1.0 1.0 3 P42771 1 +Regulation of macrophage apoptotic process 0.6294772319238024 0.7894176716528517 0.4298679307026871 1.0 1.0 3 P42771 1 +Negative regulation of oxidative phosphorylation 0.6289250160338842 0.7873844849895637 0.4310568262909764 1.0 1.0 3 P30405 1 +Protein hexamerization 0.5282327483235001 0.7867777796093528 0.4314119632765889 1.0 1.0 5 P31153,O95202,Q96TA2 3 +Organelle disassembly 0.30630606976617 0.7853309109436979 0.4322595768637955 1.0 1.0 53 O95140,P53365,Q5MNZ6,Q9Y4P1,P42858 5 +Regulation of cell substrate junction organization 0.4451790710458239 0.7842813951737797 0.4328750137785475 1.0 1.0 20 Q9HCM4,P62330,Q9Y2S7 3 +Positive regulation of dna templated transcription elongation 0.4458438785534416 0.7833970737986554 0.4333939739841685 1.0 1.0 15 Q86V81 1 +Negative regulation of response to dna damage stimulus 0.431494690443204 0.7819149505009924 0.4342645581091802 1.0 1.0 27 Q9BRJ7,Q96QC0,P14174 3 +Camera type eye morphogenesis 0.4749348929967518 0.7812011930966047 0.4346841721188572 1.0 1.0 8 Q16706,Q8NHU6,O95140 3 +Mesoderm morphogenesis 0.4907791367526861 0.7788075972142728 0.4360930617720462 1.0 1.0 7 Q9HCM4,Q96A65,P05556 3 +Negative regulation of chemotaxis 0.5261869066011591 0.7782869000234806 0.4363998965434583 1.0 1.0 5 O94813,P14174 2 +Regulation of protein import 0.4358743631731376 0.7771987391754325 0.4370415259803297 1.0 1.0 25 Q9NW64,Q13148,Q9UHD1,Q99653,Q16539,Q9H8V3,Q9NPF5 7 +Embryo implantation 0.4377805125846484 0.7751908317532592 0.438226904920683 1.0 1.0 10 P47914,P35613 2 +Actin filament bundle organization 0.3150151848433563 0.769947980489466 0.4413307507312545 1.0 1.0 47 P35080,Q9NWH9,Q9Y624,O75122,P60953,Q9Y613 6 +Regulation of cilium movement 0.8763943322279103 0.7689423152688087 0.4419275556107742 1.0 1.0 2 P57076 1 +Response to heat 0.380330037710592 0.7681373161076026 0.4424056093482125 1.0 1.0 38 O75340,O95391,O60884,Q9UHD1,P31689,O75475,P17066,Q9UI10,P31749,P25685,Q9H078 11 +Regulation of protein sumoylation 0.4880457968278351 0.7668080451860687 0.4431956523297102 1.0 1.0 7 Q9BVP2,Q9NVN8,Q9H0E2,Q9UBT2,P35222 5 +Cd40 signaling pathway 0.5232347616173755 0.7660661926852276 0.4436369175700796 1.0 1.0 5 Q9BXW9,P05556,O15360,P35232 4 +Negative regulation of t cell proliferation 0.5024060837240241 0.7631771364457822 0.4453577622202878 1.0 1.0 6 Q9Y6D9 1 +Respiratory chain complex iii assembly 0.5022667472897611 0.7625860336949388 0.4457103164122289 1.0 1.0 6 Q9BRT2 1 +Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.5019259333717598 0.7611405822486649 0.4465731033129696 1.0 1.0 6 Q9Y2P8,Q12788 2 +Positive regulation of neurotransmitter transport 0.6215319662243729 0.7602704690021483 0.4470929300496147 1.0 1.0 3 P05556,Q00535 2 +R loop disassembly 0.5632226703080938 0.7592551360436802 0.4476999494470166 1.0 1.0 4 Q9NR30,Q9NY93 2 +Negative regulation of protein kinase b signaling 0.4861130465956812 0.758346167060146 0.4482437760167688 1.0 1.0 7 Q9NZM5 1 +Regulation of histone phosphorylation 0.5011712398997725 0.7579416912405865 0.4484858902110185 1.0 1.0 6 O75367 1 +Amino acid transmembrane transport 0.4399943258654515 0.757493426078524 0.4487543028868483 1.0 1.0 14 P08195,Q96NB2,O60831 3 +Detection of mechanical stimulus 0.6203256936067562 0.7558658599152879 0.4497296248017803 1.0 1.0 3 P35222,P14923 2 +Pyrimidine nucleobase catabolic process 0.5621950934532145 0.7552672630072826 0.4500886371042352 1.0 1.0 4 Q9BPU6 1 +Nucleobase catabolic process 0.5621950934532145 0.7552672630072826 0.4500886371042352 1.0 1.0 4 Q9BPU6 1 +Regulation of ribosome biogenesis 0.6199601059127504 0.7545320549905542 0.4505298049321506 1.0 1.0 3 Q96BK5 1 +Positive regulation of stress fiber assembly 0.4401143227459995 0.7543804180586194 0.4506208264190494 1.0 1.0 15 P35080,Q9Y613 2 +Dendritic cell migration 0.5619530364781198 0.7543285157881676 0.4506519836344451 1.0 1.0 4 P60953 1 +Negative regulation of telomere maintenance 0.4391897002935721 0.753466322149108 0.4511697415867644 1.0 1.0 14 Q96BK5,P09874,P18887,Q15554,O60934,Q92878,Q00839,Q9H0A0 8 +Regulation of myeloid cell differentiation 0.4235278464128853 0.7532369651551567 0.451307529964317 1.0 1.0 28 Q96T37,P62805 2 +Mrna cleavage 0.4491620150091222 0.7420467785056972 0.4580589939235326 1.0 1.0 9 O43809 1 +Histone exchange 0.496557978566329 0.7384459251211579 0.4602435157067659 1.0 1.0 6 Q9NPF5 1 +Endosome to plasma membrane protein transport 0.5165271083817531 0.7384453574218991 0.4602438605705359 1.0 1.0 5 P61006,Q96QK1 2 +Regulation of phospholipid biosynthetic process 0.4956236832513112 0.7345101198044728 0.4626378947592156 1.0 1.0 6 P17655 1 +Response to temperature stimulus 0.2935282498590538 0.7343535161038351 0.4627333093980608 1.0 1.0 49 O75340,P20020,Q92769,Q9H2U1,O60884,O95391,P31689,Q9UHD1,O75475,P17066,P04179,Q9UI10,P31749,P25685,Q9H078,Q96HE7 16 +Positive regulation of lipid transport 0.4293377667510176 0.7339548918755107 0.4629762304827352 1.0 1.0 10 P82094 1 +Hippo signaling 0.4804231985766499 0.733551270533447 0.4632222692264878 1.0 1.0 7 Q16539,P46734 2 +Positive regulation of telomere maintenance 0.4255792796105779 0.7330159394454792 0.4635487077464315 1.0 1.0 26 O60934,P46100,Q96QC0,Q15554 4 +Axial mesoderm development 0.8640337654507015 0.7301594722749081 0.4652927120792347 1.0 1.0 2 Q9HCM4 1 +Positive regulation of mitochondrial depolarization 0.6124849215922785 0.7273765736810293 0.4669953012338796 1.0 1.0 3 P09874,P30536 2 +Blastocyst development 0.3794298575732623 0.7225702831726074 0.4699439308846909 1.0 1.0 37 P26373,Q12824,Q13503,O75175,O95140,P17655,Q6DKI1,O60934,Q9BZK7,Q13895 10 +Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4607719946686007 0.717295994704151 0.4731914781035569 1.0 1.0 8 P31749 1 +Regulation of metaphase plate congression 0.5521812368847289 0.7166442835708939 0.4735936127464648 1.0 1.0 4 Q00839,Q9Y6D9 2 +Negative regulation of leukocyte migration 0.4605269546091371 0.7162016273500341 0.4738668583839005 1.0 1.0 8 P31749,O94813,P14174,Q5JRA6 4 +Regulation of mitochondrial rna catabolic process 0.5110678296630912 0.7161249860774775 0.4739141767942141 1.0 1.0 5 Q8IYB8,Q8TCS8,Q12849 3 +Planar cell polarity pathway involved in neural tube closure 0.8583056979197974 0.7123702125656202 0.4762355560364932 1.0 1.0 2 O14641 1 +Establishment of planar polarity involved in neural tube closure 0.8583056979197974 0.7123702125656202 0.4762355560364932 1.0 1.0 2 O14641 1 +Cochlea morphogenesis 0.8583056979197974 0.7123702125656202 0.4762355560364932 1.0 1.0 2 O14641 1 +Neuroblast division 0.608262967430655 0.7121419760466624 0.4763768633051199 1.0 1.0 3 P61026,Q92974 2 +Asymmetric neuroblast division 0.608262967430655 0.7121419760466624 0.4763768633051199 1.0 1.0 3 P61026,Q92974 2 +Positive regulation of glycoprotein metabolic process 0.4593961881573713 0.7111568614363079 0.476987037309696 1.0 1.0 8 P62820 1 +Motor learning 0.8577027434428641 0.7105047296325344 0.4773911990411252 1.0 1.0 2 Q9BSH4 1 +Endonucleolytic cleavage involved in rrna processing 0.4286646319451943 0.706702402017564 0.4797514365424944 1.0 1.0 13 Q2NL82,Q14137,Q9Y2P8,Q12788 4 +Negative regulation of smoothened signaling pathway 0.5495667590268176 0.7066356876801516 0.4797929052024985 1.0 1.0 4 P17612,Q5GLZ8 2 +Lens development in camera type eye 0.4876393891786538 0.7010586151170098 0.4832664359932974 1.0 1.0 6 P28289,Q8NHU6 2 +Regulation of insulin secretion 0.42563499232114 0.7000930663326395 0.4838691856825041 1.0 1.0 23 Q8N5M9,Q8NE86,Q9BRT2,P55809 4 +Trna metabolic process 0.3643730988951859 0.6997704047520639 0.4840707000061071 1.0 1.0 92 Q12789,Q969Y2,Q8TEA1,Q5VV42,Q9H0A0,Q9UGM6,Q8WUA4,Q96B26,Q9NP81,Q9NPF4,Q5T160,Q9NXH9,Q9BW92,P62875,Q15031,Q13868,Q8N5L8,Q9Y5Q9,P62312,O75127,Q9H974,Q9UJA5,Q99575,Q5ST30,Q9Y5Q8,Q9NXG2,Q06265 27 +Response to monosaccharide 0.381245096102989 0.6990314827518309 0.4845323560699701 1.0 1.0 36 P55809,Q12824,P42574,O95563,P04179,Q9UI10,Q96ST3,Q9HCL2,Q8N5M9 9 +Establishment of cell polarity 0.3064486949932277 0.6955263410179777 0.4867255094355576 1.0 1.0 47 P62330,P42858,Q92614 3 +Negative regulation of cytoskeleton organization 0.2980170399851073 0.6954826985838051 0.4867528501049958 1.0 1.0 48 Q9UHB6,P35080,Q9NWH9,Q8WWK9,Q9Y624,O75122,O15020 7 +Membrane repolarization 0.4550534277718413 0.6918655428008033 0.4890217713438707 1.0 1.0 8 P54709,Q99996 2 +Trna 5 end processing 0.4544661768481204 0.6892672823495453 0.4906550830562128 1.0 1.0 8 P78346,Q99575,Q8N5L8,O15091 4 +Negative regulation of signal transduction in absence of ligand 0.4695659607359136 0.6867605876893594 0.4922336097487583 1.0 1.0 7 P31749 1 +Positive regulation of transcription regulatory region dna binding 0.4841273861832517 0.6864540067989073 0.4924268579717759 1.0 1.0 6 Q00403,P07305 2 +Carbohydrate derivative transport 0.4255526598576056 0.6861393176128158 0.4926252594274281 1.0 1.0 14 O15439,P41440,Q8TB61 3 +Morphogenesis of an epithelium 0.3184666124497613 0.6848128955058972 0.4934619968538212 1.0 1.0 66 Q9HCM4,Q96T37,Q9NWH9,O14641,O75122,P60953,O60568 7 +Meiosis i cell cycle process 0.4258001320860847 0.6803784263326158 0.4962648775541682 1.0 1.0 19 Q9UNM6,P46100,Q02880,O60216,Q9BTX1,O94901 6 +Positive regulation of chromosome organization 0.3127061472807845 0.6799759221290921 0.4965197067982738 1.0 1.0 46 O75367,Q9H2U1,Q15554,Q92878,Q96ST3,P35222,P17987,P39748,O60934,O95347,Q04837,O60832,Q96MF7,O60216,P46100,Q9Y6X9,Q9BVP2,Q14103,P09651,P22626,Q96QC0,P26358 22 +Glial cell development 0.4244172820862185 0.6761576553111195 0.4989405541913199 1.0 1.0 20 Q9UI10,P11047 2 +Thalamus development 0.8462466083810665 0.6753277224746966 0.4994675746234887 1.0 1.0 2 Q02218 1 +Lymphocyte apoptotic process 0.4240719760556121 0.6747969042811603 0.4998048074781231 1.0 1.0 15 P31749,P14174 2 +Protein n linked glycosylation 0.4244217193471711 0.6734281938625646 0.5006749169344347 1.0 1.0 19 O75340,P04844,Q14165,O95394,Q9Y673,Q06210,Q9BT22,P39656,Q13724,P46977 10 +Regulation of histone h3 k9 methylation 0.4202390985753768 0.6727484637232016 0.5011073296763291 1.0 1.0 12 Q12824,P46100 2 +Histone h3 k9 methylation 0.4202390985753768 0.6727484637232016 0.5011073296763291 1.0 1.0 12 Q12824,P46100 2 +Rna 3 end processing 0.3100315552424311 0.6725564303425522 0.5012295282291221 1.0 1.0 62 Q8TCS8,P22087,Q13868,O43809,Q5RKV6,Q8N201,Q06265,Q96B26,O75127,Q9NVH2,P33240,P09012,O60832 13 +Scarna localization to cajal body 0.5002361640462624 0.672306656127017 0.5013884932093291 1.0 1.0 5 Q9BUR4,O60832 2 +Regulation of granulocyte chemotaxis 0.4338348984051576 0.6713462938725298 0.5019999496883418 1.0 1.0 9 Q8NE86,O94813,Q07021 3 +Gpi anchor metabolic process 0.4803322656603683 0.6707522206935173 0.5023783897092888 1.0 1.0 6 Q969N2,Q96S52 2 +Neurotransmitter receptor transport 0.4995861454934995 0.6696982062647249 0.5030501953825652 1.0 1.0 5 P61006 1 +Trophoblast cell migration 0.5961058594115282 0.6687229994066572 0.5036721933473085 1.0 1.0 3 Q07021 1 +Dna replication independent chromatin organization 0.4796526538701975 0.6679495027482512 0.5041658268335902 1.0 1.0 6 P62805 1 +Vesicle mediated transport to the plasma membrane 0.2987904189732881 0.6672971647735266 0.504582337042877 1.0 1.0 56 O60826,Q15286,Q9UMY4,P62330,Q9Y2D4,Q07960,Q9UJY5,P51153,Q9BZG1 9 +Response to dsrna 0.4233366302678133 0.6668618177901998 0.5048604019304728 1.0 1.0 17 P08195,Q9NUD5,P41440 3 +Positive regulation of membrane depolarization 0.5390648567119172 0.6667754732914198 0.5049155614966634 1.0 1.0 4 P09874,P30536,P63244 3 +Endocytic recycling 0.4080246765015721 0.6652389298042485 0.5058976844231851 1.0 1.0 28 Q9UMY4,P62330,P51153,Q07960 4 +Regulation of oxidative stress induced cell death 0.4224261820716353 0.6634080276142531 0.507069265954855 1.0 1.0 19 P31749,Q9NWH9,Q07820 3 +Negative regulation of cellular respiration 0.5377341532345836 0.6617660111489766 0.508121192032829 1.0 1.0 4 P30405 1 +Renal water homeostasis 0.5940892641737034 0.6615891993238584 0.5082345313416119 1.0 1.0 3 P17612,O76024 2 +Regulation of atp dependent activity 0.3973613166791817 0.6610068726922498 0.5086079060913218 1.0 1.0 31 P35080,P08621,P54709,Q9Y3Y2,Q5JTV8,P30405,Q9UII2 7 +One carbon metabolic process 0.419168365107163 0.6608183493429354 0.5087288138312802 1.0 1.0 13 P34896 1 +Centromere complex assembly 0.4633911915987886 0.6604864350594685 0.5089417206515263 1.0 1.0 7 Q7Z7K6 1 +Muscle cell proliferation 0.4093878254406482 0.65762760253867 0.5107774533815115 1.0 1.0 27 O95140,Q9Y2S7,Q5SW96,Q16539,P04179,P61586,P31749,Q15637,P08069,Q5VZE5 10 +Cortical cytoskeleton organization 0.4118218744136009 0.6574978956580675 0.5108608236207908 1.0 1.0 26 O43491,O75083,P62330,Q9H8V3,P51153,Q9Y613 6 +Release of cytochrome c from mitochondria 0.421075725216079 0.6557405205549973 0.5119910923964366 1.0 1.0 17 P31749,P30405,Q96A26,P04179 4 +Regulation of synaptic transmission glutamatergic 0.5357677055927651 0.6543811065415096 0.5128663036432206 1.0 1.0 4 Q15042,Q00535 2 +Proton transporting v type atpase complex assembly 0.839312631896281 0.6542943349954025 0.5129221949290175 1.0 1.0 2 Q8N511 1 +Vacuolar proton transporting v type atpase complex assembly 0.839312631896281 0.6542943349954025 0.5129221949290175 1.0 1.0 2 Q8N511 1 +Cardiac conduction system development 0.8390111546578156 0.6533844468297512 0.5135084631208493 1.0 1.0 2 P60953 1 +Lamellipodium assembly 0.4195952183818798 0.6517745680457598 0.5145466101956924 1.0 1.0 20 P60953,P53365 2 +Positive regulation of leukocyte chemotaxis 0.4158253873196961 0.6517542440057557 0.5145597233339614 1.0 1.0 12 Q8NE86,P78536 2 +Synapse assembly 0.4195603504217894 0.6499571612711584 0.515719893447661 1.0 1.0 16 O15020 1 +Axon extension 0.4012803519734439 0.6444430960728031 0.5192881461774155 1.0 1.0 29 Q13740 1 +Arf protein signal transduction 0.5330316742081462 0.6441421952244724 0.519483230705398 1.0 1.0 4 Q9NP61,Q15555,Q8N6T3 3 +Pyramidal neuron development 0.5890478990536974 0.6438456906302461 0.5196755019791799 1.0 1.0 3 Q02218 1 +Positive regulation of glucose transmembrane transport 0.4736107765752425 0.6431593225917354 0.5201207248014266 1.0 1.0 6 P31749 1 +Arp2 3 complex mediated actin nucleation 0.4181113780286162 0.6429380662137602 0.5202642879423631 1.0 1.0 16 P53365 1 +Regulation of dna helicase activity 0.5886149364926396 0.642328016811219 0.5206602268663056 1.0 1.0 3 Q04837 1 +Regulation of action potential 0.4100880891430303 0.6423243985300738 0.5206625756937884 1.0 1.0 10 Q9HD47,Q99996,P14923,Q14126 4 +Cellular amino acid catabolic process 0.372259087121958 0.6418300626648413 0.5209835279031805 1.0 1.0 36 P36957,P52758,P00505,P26440,O15382,Q96RQ3,Q8TD30,P34896,P38117,P30038 10 +Regulation of lyase activity 0.4582730937297593 0.6389110139015451 0.5228808225890116 1.0 1.0 7 Q01518,Q99996,P40123,Q9H1K1 4 +Positive regulation of vascular associated smooth muscle cell proliferation 0.4916598697463957 0.6380982972057421 0.523409694947607 1.0 1.0 5 O95140 1 +Neuron death in response to oxidative stress 0.4578629622216053 0.6371904156356397 0.5240008198908979 1.0 1.0 7 P09874,Q15233,Q07820 3 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.4907389933108828 0.6344527593424146 0.525785387415409 1.0 1.0 5 Q3LXA3 1 +Ribosome biogenesis 0.5167763671526523 0.6336573735327875 0.5263044492459292 1.0 1.0 207 P22087,P55769,Q2NL82,Q68CQ4,P62857,Q9BYD6,Q9Y3A5,Q9NYY8,Q07021,Q9NVU7,Q8TCT8,Q9Y5A9,P46087,P62081,Q8TDN6,Q96B26,Q7Z478,Q13868,Q9NR30,Q99848,O15213,P62847,Q99547,P62312,Q96BK5,Q96DE0,Q14137,Q9BSC4,O00541,P18077,P50914,Q9NX58,Q9H501,P82912,Q9Y4W2,Q8TDD1,O43709,Q9NZM5,P61353,Q9H7B2,Q9GZR2,Q96GQ7,Q9Y3A2,O75683,Q8IY81,Q9Y237,Q9NUL7,Q02878,P62424,Q9NY93,Q9UHA3,Q567V2,Q13610,O75616,Q9Y6V7,O95478,Q6DKI1,Q5RKV6,Q969S3,Q9H9L3,Q9H583,P83731,P62750,P62841,Q9H0A0,Q9NVP1,Q13823,O60832,O76021,P63173,Q12788,Q14684,Q9BY44,Q9BYG3,Q9H0S4,Q9UNQ2,Q9Y2P8,Q9Y2R9,Q9BZE4,P39023,Q9H9Y2,Q13895,Q06265 83 +Nervous system process involved in regulation of systemic arterial blood pressure 0.8314742236961078 0.630766257902768 0.52819336881134 1.0 1.0 2 P04179 1 +Positive regulation of release of cytochrome c from mitochondria 0.4560318590592966 0.6295239954557114 0.5290060644883479 1.0 1.0 7 P30405,Q96A26 2 +Cellular response to dsrna 0.4069796652395413 0.6278827662058156 0.530080741446783 1.0 1.0 10 P41440 1 +Regulation of adenylate cyclase activity 0.4882836118260318 0.6247597737042437 0.5321287357203339 1.0 1.0 5 Q01518,Q99996,P40123 3 +Gliogenesis 0.2920793953578519 0.6244411763067781 0.5323378903842184 1.0 1.0 55 Q9UI10,P11047,Q15382 3 +Negative regulation of blood circulation 0.5829312424607949 0.6224985479720347 0.5336140982611466 1.0 1.0 3 P05023,P16615 2 +Regulation of telomere maintenance 0.352829366956175 0.6216294167359033 0.5341855733896257 1.0 1.0 39 P46100,Q9H2U1,P09874,P18887,Q96BK5,P49750,Q15554,Q92878,O60934,Q00839,Q96QC0,Q9H0A0,Q01780,P35222,O60832 15 +Branched chain amino acid metabolic process 0.4123892041723993 0.6186175909569159 0.5361683105626824 1.0 1.0 15 A1L0T0,P09622,P26440,O15382,Q96RQ3,Q9HCC0 6 +Regulation of ras protein signal transduction 0.3820969190846252 0.6179640309594405 0.5365990490772294 1.0 1.0 33 Q9NWH9,P62330,Q9Y624,Q5VZ89,P41440 5 +Positive regulation of pattern recognition receptor signaling pathway 0.4046823866435677 0.617279610147568 0.5370503133908855 1.0 1.0 10 P41440 1 +Trna modification 0.3895848460118012 0.616509635581427 0.5375582144319309 1.0 1.0 31 Q9NXH9,Q9UJA5,Q969Y2,Q8TEA1,Q5VV42,Q9H974,Q9NPF4 7 +Amino acid transport 0.4130592771272673 0.616280872939331 0.5377091604172781 1.0 1.0 18 P08195,Q96NB2,Q6P4A7,O60831 4 +Triglyceride biosynthetic process 0.4664051294139122 0.6139082428282139 0.5392759629437707 1.0 1.0 6 Q92604 1 +Regulation of neutrophil chemotaxis 0.4521027644037291 0.6131612092037624 0.5397697510051658 1.0 1.0 7 Q8NE86,O94813,Q07021 3 +Ribonucleoprotein complex subunit organization 0.4093157068265521 0.6125842953176022 0.5401512450133816 1.0 1.0 128 Q14137,P83731,P09234,Q02878,Q9ULW3,P62750,P62841,P55769,Q9UKA9,P62857,Q9UMS4,P20042,P39019,O75643,P82912,Q9NYY8,Q13247,Q15056,Q13242,O95391,Q15428,Q9NQ55,O94906,P46087,P46777,P40429,O75616,Q99590,Q8TDN6,Q7L2E3,P57678,Q7Z478,Q9NZM5,Q92879,Q9ULR0,Q15185,P63173,O43809,P62318,P62314,Q9Y2R9,Q9BZJ0,Q9H7B2,P39023,Q6P2Q9,P62304,O75475,O95400,Q9BUQ8,Q9Y312,Q15637,Q9NUL7,Q86UA1 53 +Regulation of atp biosynthetic process 0.4519635129697642 0.6125835324389086 0.5401517495690382 1.0 1.0 7 P09874 1 +Axoneme assembly 0.579957837065778 0.6121961508012911 0.5404079879880195 1.0 1.0 3 A0AVF1 1 +Regulation of cellular ketone metabolic process 0.4120242898869171 0.6118619831298525 0.5406290761914294 1.0 1.0 17 P31749,Q15120,Q92604 3 +Negative regulation of protein autophosphorylation 0.8242387699728582 0.6092941753071522 0.5423294671959289 1.0 1.0 2 Q99653 1 +Negative regulation of protein import into nucleus 0.8242387699728582 0.6092941753071522 0.5423294671959289 1.0 1.0 2 Q99653 1 +Triglyceride metabolic process 0.4064846643406018 0.6080492766001272 0.5431547923356828 1.0 1.0 12 Q9BZK7,Q92604 2 +Cristae formation 0.4354497978086842 0.6066104835572971 0.5441094412822747 1.0 1.0 8 Q9NVH1,Q9Y4W6,Q9BUR5,Q9Y512,O95202 5 +Chromatin assembly or disassembly 0.3228044264302231 0.6060292350055785 0.5444953401049966 1.0 1.0 74 P10412,O75367,Q12824,P46100,P16403,P16402,Q9P0M6,P17096,Q96ST3,Q96T23,Q5SSJ5,Q7Z7K6,Q92522,P62805,P07305 15 +Post embryonic animal morphogenesis 0.8227313837805166 0.6048516586256106 0.5452775657389834 1.0 1.0 2 P46100 1 +Multi multicellular organism process 0.3907680420063194 0.6039233340981118 0.5458946143949237 1.0 1.0 30 P17655,Q9Y6I3,P47914,P35613,P31749,P41440 6 +Negative regulation of rna splicing 0.4103360102407412 0.6038226596815767 0.5459615525450161 1.0 1.0 19 Q13247,Q07021,P62277,Q9UKA9,P62854,Q9BTD8 6 +Cellular component maintenance 0.4055482288835027 0.6037252144393921 0.5460263475012987 1.0 1.0 12 Q9BRK5 1 +Rho protein signal transduction 0.4034499809490238 0.60224684722492 0.5470098360919442 1.0 1.0 25 Q9Y624,Q9NWH9,P41440,Q07960 4 +Nitric oxide synthase biosynthetic process 0.5216056953656516 0.6018634518438885 0.5472650342222514 1.0 1.0 4 P46734 1 +Positive regulation of nitric oxide synthase biosynthetic process 0.5216056953656516 0.6018634518438885 0.5472650342222514 1.0 1.0 4 P46734 1 +Viral protein processing 0.4179978306079364 0.600477185771889 0.5481882609555795 1.0 1.0 9 Q16706 1 +Epithelial tube morphogenesis 0.3489817388512 0.5965209402912441 0.5508272690616218 1.0 1.0 39 Q96T37,O14641 2 +Fat cell differentiation 0.392339705653876 0.595381190420832 0.5515886957398317 1.0 1.0 29 Q8WTT2,Q16539,P04179,Q9BRK5,P31749,Q9BZK7,O75962 7 +Rrna base methylation 0.4615084070455936 0.5942390980964801 0.5523522057914587 1.0 1.0 6 O43709 1 +Fructose 6 phosphate metabolic process 0.4472990957163832 0.5933249102927771 0.5529637309614932 1.0 1.0 7 P52789,P37837,Q06210,P17858 4 +Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.4062949856288441 0.5893723220216003 0.5556115392953183 1.0 1.0 21 Q14137,O00541,Q13868,Q9Y2P8,Q96B26,Q8IY81,Q06265 7 +Trna 3 end processing 0.4791886618744844 0.5892180042422076 0.5557150410153187 1.0 1.0 5 O75127 1 +Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.4599186251491672 0.5878915010804779 0.5566051214263181 1.0 1.0 6 Q9UII2 1 +Regulation of organ growth 0.4035221443655479 0.587447762843439 0.5569030237548498 1.0 1.0 13 P31749,Q16539 2 +Epithelial cell cell adhesion 0.517589414901797 0.5871977004797511 0.5570709365875186 1.0 1.0 4 P14923 1 +Positive regulation of mitochondrial fission 0.430860131898735 0.5871338471821006 0.5571138169964021 1.0 1.0 8 Q9NX47 1 +Anion transmembrane transport 0.3581455009544333 0.5858154425852181 0.5579995450720687 1.0 1.0 37 O43808,O60831,O15439,Q00325,P08195,P41440,Q8TB61 7 +Cellular response to oxidised low density lipoprotein particle stimulus 0.8151944528188007 0.582804189254103 0.5600251245047223 1.0 1.0 2 P31749 1 +Membrane protein ectodomain proteolysis 0.3988985851785863 0.5815036402678556 0.5609010655265145 1.0 1.0 11 Q8TCT8 1 +Regulation of glial cell proliferation 0.5157000159874834 0.5803355735597883 0.5616883424742991 1.0 1.0 4 P30536,O94874 2 +Tetrahydrofolate interconversion 0.4440558458905067 0.580041865002927 0.5618863860612255 1.0 1.0 7 Q6UB35,P34896 2 +Cell killing 0.4033708831491568 0.579560812042767 0.562210826253944 1.0 1.0 22 Q9NVJ2,P81605,P04406,P51809,P04439,Q9BY67,P05204 7 +Positive regulation of actin filament bundle assembly 0.4042019033533838 0.5769425279584336 0.5639782803261877 1.0 1.0 16 P35080,Q9Y613 2 +Endoplasmic reticulum calcium ion homeostasis 0.4284388222505878 0.5769403628950431 0.5639797429435904 1.0 1.0 8 Q9Y3D6,Q9UM00,Q07812,O76024,P16615 5 +Purine nucleoside diphosphate catabolic process 0.8127826349110581 0.5758085284272114 0.5647446083501004 1.0 1.0 2 Q9BW91 1 +Base conversion or substitution editing 0.475658626988977 0.5755849960501888 0.5648957249210667 1.0 1.0 5 A0AV96 1 +Positive regulation of signal transduction by p53 class mediator 0.3974098327240691 0.5747781328626921 0.5654413575098027 1.0 1.0 11 P60866,P62841,O43324 3 +Positive regulation of supramolecular fiber organization 0.2994065661342717 0.5746562486886555 0.5655238023876632 1.0 1.0 46 Q8NBJ5,Q9Y281,O75083,P35080,Q9NWH9,Q99996,P62330,O15144,P60953,Q9Y613 10 +Regulation of response to oxidative stress 0.4011602421564778 0.5744714246109377 0.5656488320848538 1.0 1.0 23 P31749,O75367,Q9NWH9,Q07820 4 +Chromosome condensation 0.3996777467422236 0.5742707042341506 0.5657846303399052 1.0 1.0 24 P10412,P16403,Q9ULX6,Q92522,P07305 5 +Actin cytoskeleton reorganization 0.3977283061349892 0.5730764273237623 0.5665929471818354 1.0 1.0 25 Q8NE86,Q9Y5S2,Q9Y624,Q13576 4 +Membrane docking 0.3806318555739559 0.5668240592433411 0.5708337228477189 1.0 1.0 31 Q99653,Q92930,Q7Z6M1 3 +Sensory perception of light stimulus 0.4019216636516229 0.5635928590236143 0.5730312477957606 1.0 1.0 19 Q9H6K4 1 +Regulation of striated muscle contraction 0.3981778070420027 0.5631004880165914 0.5733664592082415 1.0 1.0 13 P17612,Q14126,Q9HD47,Q99996,P15924,P14923,P16615 7 +Aerobic respiration 0.3452897254569696 0.5625762101184862 0.5737234953519643 1.0 1.0 91 P56134,O75438,P50213,O43676,P48047,P61586,Q96I99,Q99798,P30405,Q9UJZ1,Q9UDW1,P10515,P19404,Q02218,P08559,P28331,Q9NZM5,P14927,O14548,P20674,Q9BRT2,O75380,P08574,P03915,P36957,O95139,Q9BSK2,O95168,Q9P2R7,Q16795,O14949 31 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.472238564023964 0.5624678658242792 0.5737972915483847 1.0 1.0 5 P04179,O75787 2 +Regulation of protein localization to cell surface 0.3989938474276154 0.5609915866814249 0.5748032726360814 1.0 1.0 14 P31749,P62330,Q92544,Q9HD47 4 +L phenylalanine metabolic process 0.5642340168878172 0.5585908167632869 0.576441008754895 1.0 1.0 3 P16930,P09417 2 +Aromatic amino acid family catabolic process 0.5642340168878172 0.5585908167632869 0.576441008754895 1.0 1.0 3 P16930,P09417 2 +Branched chain amino acid biosynthetic process 0.8067530901416855 0.5584498580185153 0.5765372351233464 1.0 1.0 2 O15382 1 +Cell junction assembly 0.307778807891226 0.5540946358670801 0.5795140810165473 1.0 1.0 69 Q9HCM4,P11047,Q9Y2S7,P62330,Q9Y624,P60953,O15020,P51153,P41440 9 +Mitochondrion morphogenesis 0.3945644040831614 0.5538532603297925 0.5796792747694113 1.0 1.0 12 Q07812,Q8TCS8,Q9Y2S7 3 +Negative regulation of epithelial cell migration 0.3926867371076948 0.5536358719407015 0.5798280709849613 1.0 1.0 11 P35080,P58107,P57105,P51608,P61586,P67870,O94813,P14923 8 +Cortical actin cytoskeleton organization 0.3988229467351162 0.5532954327926363 0.5800611279539982 1.0 1.0 21 P62330,Q9Y613 2 +Gastrulation 0.3870701065377915 0.5527759576473619 0.5804168335336746 1.0 1.0 28 Q9HCM4,O75122,O14641 3 +Positive regulation of dna replication 0.3989263782932692 0.5526200192924585 0.5805236307521233 1.0 1.0 16 P60953,Q9ULV3 2 +Negative regulation of gene expression epigenetic 0.3840117327536423 0.5511128867394458 0.5815562919572441 1.0 1.0 29 O75367,Q9Y6X9,Q9P0M6,P51608,Q96ST3,Q7Z7K6,P07305 7 +Calcium mediated signaling using intracellular calcium source 0.5618214716525962 0.5505043167641938 0.5819735168889093 1.0 1.0 3 P17612,Q9Y3D6 2 +Regulation of nitric oxide synthase activity 0.4214056216709303 0.5476671043960443 0.5839205035276995 1.0 1.0 8 P31749 1 +Regulation of systemic arterial blood pressure by renin angiotensin 0.8022309315646592 0.5455564126024532 0.5853708929216617 1.0 1.0 2 O75787 1 +Bone maturation 0.8022309315646574 0.545556412602448 0.5853708929216652 1.0 1.0 2 Q15125 1 +Cerebellar cortex development 0.3938051057617912 0.5434759496596959 0.5868021455465557 1.0 1.0 13 Q02218,O15020 2 +Negative regulation of apoptotic signaling pathway 0.2994348948461908 0.5421010228929951 0.5877489141055903 1.0 1.0 65 P05141,Q8N2F6,P31689,Q7LG56,Q07820,Q07812,P04179,P31749,P16989,P42858,P30405,P14174,Q9P0J0 13 +Acetyl coa metabolic process 0.396251533864174 0.5404483879695204 0.5888878453878814 1.0 1.0 16 P36957,P10515,Q15120,O95563,P08559,Q03426 6 +Response to alcohol 0.3020870421487368 0.5401463814809443 0.589096086482082 1.0 1.0 45 P55809,P00505,P54132,P09874,Q9NRA0,P61353,P04179,P61586,Q9BRK5,P31749,O00487,O94813,Q9NPF5,P08069,P14923 15 +Myeloid leukocyte differentiation 0.3866017723018073 0.5378897724535391 0.5906531497232292 1.0 1.0 27 O00625,Q8N5M9,P60953,Q16539 4 +Glucose metabolic process 0.2832510613879673 0.5368005217105095 0.5914054112630449 1.0 1.0 56 P62140,P10515,Q9BYT8,P04406,Q15120,Q96C23,Q9UBX3,Q16539,P11498,P31749,P08559,P62136,Q6PJG6,P52789 14 +Copper ion homeostasis 0.503353938763687 0.5361152165193397 0.5918789242710831 1.0 1.0 4 O60826 1 +Selective autophagy 0.3749148642860213 0.5360389958385146 0.5919315998601711 1.0 1.0 31 Q9Y4P1,P42858,P53365 3 +Mrna transport 0.3138443549753573 0.5360375797474349 0.5919325785313565 1.0 1.0 74 Q9HAU5,Q86V81,P37198,Q9UKX7,P49790,Q9Y3Y2,Q9BY77,Q86U42,Q86W42,O00159,Q9ULX6,Q9UN86,Q9Y6M1,Q5SRE5,Q9BTX1,O75152,P78406,Q8NFH5,Q6P6C2,Q8NI27,Q8TEM1 21 +Alpha amino acid catabolic process 0.3781395797710079 0.5360024423372703 0.5919568624974434 1.0 1.0 30 P36957,P00505,P26440,O15382,Q96RQ3,Q8TD30,P34896,P30038 8 +Neutral amino acid transport 0.4465304928908442 0.5352345439484575 0.5924876822225711 1.0 1.0 6 P08195 1 +Lens fiber cell differentiation 0.556960487058046 0.5343299895897676 0.5931132470638631 1.0 1.0 3 P28289 1 +Modified amino acid transport 0.446029683544126 0.5332940250320934 0.5938300630742286 1.0 1.0 6 P41440 1 +Negative regulation of atp metabolic process 0.3879459427714958 0.5327235376563761 0.5942249701546372 1.0 1.0 11 P09874,P30405 2 +Protein localization to endosome 0.3896523565470755 0.5320863554058407 0.5946661871661154 1.0 1.0 12 P35241,P62330,Q15286 3 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.3851883211175002 0.5299345498670779 0.5961573104736766 1.0 1.0 10 Q9NZM5,Q3LXA3 2 +Exocytic process 0.3945989651866442 0.5294969266093975 0.5964607758910347 1.0 1.0 19 Q92930,Q7Z6M1 2 +Proteasome assembly 0.4313532203251921 0.5289334237409208 0.5968516348245128 1.0 1.0 7 Q9BT73 1 +Histone h4 deacetylation 0.5552323533758474 0.5286190869443688 0.5970697169014951 1.0 1.0 3 Q92769 1 +Actin nucleation 0.3935917587749207 0.5260789494716653 0.5988333539162287 1.0 1.0 17 P53365 1 +Rna splicing via endonucleolytic cleavage and ligation 0.4623078431577599 0.5249178129076171 0.5996403258856606 1.0 1.0 5 Q9Y224,Q9Y3I0 2 +Regulation of protein kinase c signaling 0.7943925233644793 0.5234720985778335 0.6006457625647246 1.0 1.0 2 Q02952 1 +Homologous recombination 0.3997288408272189 0.5220641439172128 0.6016256705434246 1.0 1.0 9 P11388,P46100,Q02880,Q9BXW9,Q92878,O60216 6 +Oxaloacetate metabolic process 0.4295643956957323 0.5218607803234254 0.6017672670796821 1.0 1.0 7 P00505,Q16822,P53396,Q9NQR4,P40925 5 +Regulation of cardiac muscle contraction 0.3869085414655482 0.5200813212579481 0.6030068965933406 1.0 1.0 12 Q14126,Q9HD47,Q99996,P15924,P14923,P16615 6 +Glucan biosynthetic process 0.3866702401016733 0.5190440170628986 0.603730046425673 1.0 1.0 12 P31749,P62140 2 +Positive regulation of amine transport 0.4983408748114649 0.5184847784852634 0.6041200775583675 1.0 1.0 4 Q15041,P05556,Q15042 3 +Positive regulation of amino acid transport 0.4983408748114649 0.5184847784852634 0.6041200775583675 1.0 1.0 4 Q15041,P05556,Q15042 3 +Voluntary musculoskeletal movement 0.4976123724455406 0.5159391722045493 0.6058968938839326 1.0 1.0 4 Q96QK1,P18887 2 +Branched chain amino acid catabolic process 0.3887964400850691 0.5154801200800054 0.6062175579929918 1.0 1.0 14 P09622,P26440,O15382,Q96RQ3,Q9HCC0 5 +Response to reactive oxygen species 0.3303882960099631 0.5149727102783443 0.6065720899449696 1.0 1.0 40 Q99720,P17655,P42574,Q9NWH9,P04179,P31749,Q05086,P03915,P30405 9 +Tongue development 0.5507088310598043 0.5137707133032129 0.6074123060046763 1.0 1.0 3 Q92769 1 +Tongue morphogenesis 0.5507088310598043 0.5137707133032129 0.6074123060046763 1.0 1.0 3 Q92769 1 +Hair follicle placode formation 0.5507088310598043 0.5137707133032129 0.6074123060046763 1.0 1.0 3 Q92769 1 +Ectodermal placode development 0.5507088310598043 0.5137707133032129 0.6074123060046763 1.0 1.0 3 Q92769 1 +Fungiform papilla development 0.5507088310598043 0.5137707133032129 0.6074123060046763 1.0 1.0 3 Q92769 1 +Fungiform papilla morphogenesis 0.5507088310598043 0.5137707133032129 0.6074123060046763 1.0 1.0 3 Q92769 1 +Regulation of cholesterol biosynthetic process 0.4591968278620414 0.5133278843259017 0.6077219817725221 1.0 1.0 5 O75477,Q9UBM7 2 +Negative chemotaxis 0.7901718420259287 0.5117238800474673 0.608844270778651 1.0 1.0 2 P61586 1 +Roundabout signaling pathway 0.7901718420259287 0.5117238800474673 0.608844270778651 1.0 1.0 2 P61586 1 +Tangential migration from the subventricular zone to the olfactory bulb 0.7901718420259225 0.5117238800474508 0.6088442707786625 1.0 1.0 2 Q02218 1 +Regulation of cell junction assembly 0.3702556600420948 0.5115319367939606 0.6089786313291023 1.0 1.0 31 Q9HCM4,Q9Y2S7,P62330,Q9Y624,P41440 5 +Regulation of membrane repolarization 0.4583731867368903 0.510273913366383 0.6098595759452135 1.0 1.0 5 Q99996 1 +Modification of postsynaptic structure 0.4261686274444468 0.5085243746962022 0.6110856496393109 1.0 1.0 7 P35080 1 +Regulation of chromatin organization 0.3893114577655036 0.5069247293033761 0.6122076335117619 1.0 1.0 17 Q66K74,O75367,Q96ST3,P46013 4 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.3868165211833231 0.5068300437273244 0.6122740740895547 1.0 1.0 14 Q92769,Q06124,Q9NRA0,P30046,Q02952,Q92974,P14174 7 +Positive regulation of lamellipodium assembly 0.3816609858792262 0.5055033768041703 0.6132053273086746 1.0 1.0 11 P60953 1 +Small rna loading onto risc 0.4570472272264084 0.5053703260155104 0.6132987567362842 1.0 1.0 5 Q9UPY3,O94992 2 +Placenta development 0.3817192472402217 0.5033757446259828 0.6147001215699095 1.0 1.0 26 P31749,Q96T37,P35613 3 +Morphogenesis of a branching structure 0.3886001696891316 0.5032601497830334 0.6147813800765651 1.0 1.0 20 Q96T37 1 +Regulation of telomere capping 0.3949697888698 0.5023106342903926 0.6154490299474971 1.0 1.0 9 Q15554 1 +Pteridine containing compound metabolic process 0.3885378989134227 0.5021501967222923 0.6155618727627081 1.0 1.0 18 P41440 1 +Negative regulation of leukocyte proliferation 0.4240810652860549 0.5003855066138218 0.6168036565942414 1.0 1.0 7 Q9Y6D9 1 +Insulin secretion 0.3765977084590698 0.4999112317503252 0.6171375832846708 1.0 1.0 28 Q8N5M9,Q8NE86,Q9BRT2,P55809 4 +T cell apoptotic process 0.3798024647327848 0.4975688614655882 0.6187879557804448 1.0 1.0 11 P31749 1 +Positive regulation of microtubule polymerization or depolymerization 0.3871199293203925 0.4972388175354076 0.6190206509057139 1.0 1.0 17 Q9NWH9,Q99996 2 +Dna dependent dna replication 0.3215170931489829 0.4956179287505777 0.6201640009992182 1.0 1.0 82 P46100,P54132,Q9Y2S7,Q8NFC6,Q8WTT2,P0CG13,Q86V81,Q9NY93,Q15554,O60934,Q9ULV3,Q7L590,P41440 13 +Regulation of cell matrix adhesion 0.3842308302974417 0.4934788522314239 0.6216742788648233 1.0 1.0 23 Q9HCM4,Q9Y2S7,P42771,P61586,O75122,P46939 6 +Negative regulation of protein localization 0.2672448778729556 0.4931409557251187 0.6219129940069903 1.0 1.0 50 O75367,Q9NQ48,Q9UMY4,Q06124,P31689,Q9BXS4,Q99653,Q9UHD1,Q13492,P62330,O95602,Q96ST3,P40939,Q96QK1,Q8N5M9,O75608 16 +Positive regulation of dna binding 0.3833619136231602 0.4918897578794852 0.6227972791384717 1.0 1.0 14 P09874,Q00403,P07305,Q96BK5 4 +Negative regulation of histone methylation 0.3783399042989678 0.4913627709204458 0.6231698906114005 1.0 1.0 11 O75367 1 +Glial cell apoptotic process 0.4531628813343415 0.491098922452922 0.6233564836021035 1.0 1.0 5 Q02952 1 +Modification of synaptic structure 0.407031508403107 0.4895266717956018 0.6244688764146278 1.0 1.0 8 P35080 1 +Progesterone receptor signaling pathway 0.489862662490199 0.4891280053654279 0.6247510755774521 1.0 1.0 4 Q969T9 1 +Heterochromatin organization 0.3689092334791672 0.4886828297048088 0.6250662617016072 1.0 1.0 30 O75367,Q92769,Q9Y6X9,P51608,Q96ST3,Q5SSJ5,Q7Z7K6,A6NHR9,P07305 9 +Cell death in response to oxidative stress 0.3797028980526364 0.4852836803830333 0.6274751302026103 1.0 1.0 25 Q99720,Q9NWH9,Q07820,P04179,P31749 5 +Glucose catabolic process 0.3741311574493817 0.482742594040367 0.6292785157652174 1.0 1.0 10 P19367,P09104,P04637,P17858,Q01813,P08237,O75746,P52789,P06733 9 +Rna secondary structure unwinding 0.4876114595563181 0.4814344881774571 0.6302077300514854 1.0 1.0 4 Q08211,Q9H2U1 2 +Cellular response to alkaloid 0.4190375510780902 0.4809161828487494 0.630576070739767 1.0 1.0 7 P54132 1 +Cell recognition 0.3785091730444264 0.4797085343779103 0.6314346585469461 1.0 1.0 25 Q9BY67,P35613,Q92614 3 +Autophagosome organization 0.3532183344432907 0.4795007459914098 0.6315824376378654 1.0 1.0 34 O75396,O95140,P53365,Q15286,Q5MNZ6,Q9Y4P1,P20339,P78356,P62820 9 +Cell chemotaxis 0.3444982137657906 0.4783202706731463 0.6324222709326515 1.0 1.0 36 Q9NWH9,P35613,Q8NE86,P51153,P14174 5 +Diadenosine polyphosphate metabolic process 0.5396481715178872 0.4781036602032799 0.6325764270710734 1.0 1.0 3 Q9BW91 1 +Rna dependent dna biosynthetic process 0.3345169166152546 0.4758672003919545 0.6341689907752486 1.0 1.0 38 Q96BK5,Q15554,Q9H0A0,P41440,O60832 5 +Response to hydroxyurea 0.4175529053282535 0.4752387494455301 0.6346168107434607 1.0 1.0 7 P54132 1 +Regulation of protein localization to chromosome telomeric region 0.3776917691132299 0.4736715355923653 0.6357341544233657 1.0 1.0 13 Q9BUR4,O75367,O60832,Q9BVP2,P17987 5 +Regulation of actin filament organization 0.3083115292213058 0.4715709524378976 0.6372330642823414 1.0 1.0 76 Q9UHB6,Q9Y281,P35080,P53365,Q9NWH9,P62330,O15144,Q9Y624,O75122,P60953,O15020,Q9Y613 12 +B cell homeostasis 0.4476127726207354 0.4709570203079307 0.6376714276387196 1.0 1.0 5 P42574,P14174 2 +Mitochondrial adp transmembrane transport 0.5370138048683897 0.4697486542433289 0.6385346023097518 1.0 1.0 3 P05141 1 +Regulation of vesicle size 0.4836841574817598 0.4681189806992267 0.6396995064650621 1.0 1.0 4 P20339 1 +Nuclear body organization 0.4283205737331558 0.4661790525023745 0.641087342026351 1.0 1.0 6 Q9BPY3,Q9BUR4,Q15637 3 +Positive regulation of sodium ion transmembrane transport 0.3701135768289388 0.4660671560378362 0.6411674317292522 1.0 1.0 10 Q99653,P54709 2 +Negative regulation of macrophage migration 0.7732891166716769 0.4657894680431617 0.6413662044789676 1.0 1.0 2 P14174 1 +Negative regulation of macrophage chemotaxis 0.7732891166716769 0.4657894680431617 0.6413662044789676 1.0 1.0 2 P14174 1 +Retrograde transport endosome to golgi 0.3276030741783843 0.4657567233185344 0.6413896452821133 1.0 1.0 39 Q9HA65,Q9UMY4 2 +Negative regulation of ubiquitin protein ligase activity 0.4007180610742197 0.464773178954169 0.6420938968435144 1.0 1.0 8 P62841,P60866,P62081,P46777 4 +Regulation of glucose transmembrane transport 0.375551851830633 0.4647204998733891 0.6421316259654912 1.0 1.0 13 Q06124,Q16539,P31749,P52789,Q9UKG1 5 +Regulation of atp metabolic process 0.3639566375570066 0.4641777868687343 0.6425203745327595 1.0 1.0 30 O14548,P09874,Q9BSK2,Q9BRT2,P61586,P30405,Q9UII2 7 +Nad metabolic process 0.3744706594071333 0.4602281485282379 0.6453524685116183 1.0 1.0 13 P19367,P09104,Q16822,P04637,Q4G0N4,P43304,P17858,Q01813,P08237,O75746,P52789,P06733 12 +Positive regulation of histone h3 k9 acetylation 0.4811311432288512 0.4595370182442165 0.6458485751927756 1.0 1.0 4 Q12824 1 +Fear response 0.5335181140210001 0.4587485453506238 0.6464147487155201 1.0 1.0 3 P51608 1 +Chondrocyte development 0.7705758215254748 0.458571903148318 0.6465416171088862 1.0 1.0 2 Q9NX62 1 +Import into cell 0.3780902885962674 0.4584285767797835 0.6466445648754515 1.0 1.0 21 P31749,P41440,P08195 3 +Lipid phosphorylation 0.7702743442870075 0.4577728647630531 0.6471156327503429 1.0 1.0 2 Q9NRA0 1 +Poly a plus mrna export from nucleus 0.3838003365292283 0.4571696413368186 0.6475491173691679 1.0 1.0 9 Q86U42,Q8NI27,O75152,Q9BY77 4 +Quinone metabolic process 0.4125345777636391 0.4562353854718861 0.6482207223702767 1.0 1.0 7 Q8NI60 1 +Positive regulation of atp dependent activity 0.3758462598053158 0.455476808280739 0.6487662485518098 1.0 1.0 23 Q5JTV8,Q9Y3Y2,P35080 3 +Regulation of chemotaxis 0.3690948002092586 0.4531744368657236 0.6504231383479762 1.0 1.0 27 Q8NE86,Q9NWH9,P14174 3 +Telomere maintenance via telomere lengthening 0.3142866865374445 0.4521821178749307 0.6511377894270063 1.0 1.0 41 Q15185,Q9BUR4,Q9H2U1,P09874,Q96BK5,Q15554,Q92878,Q00839,Q9H0A0,Q01780,P35222,P41440,O60832,P35251 14 +Mitochondrial outer membrane permeabilization involved in programmed cell death 0.3687127902798209 0.4513803378732562 0.6517154519022366 1.0 1.0 11 P30405,P05141,Q9UII2 3 +Glutamine family amino acid catabolic process 0.3970685763791031 0.450699191862317 0.6522063648847396 1.0 1.0 8 P30038 1 +Peptidyl lysine methylation 0.3139713259720857 0.4503233132181665 0.6524773312730208 1.0 1.0 41 P10412,O75367,Q12824,P46100,P16403,P16402,Q13610,Q15291,P51608,Q96L73,Q6UXN9 11 +Actin mediated cell contraction 0.3754367860526695 0.4497916804021786 0.6528606572792348 1.0 1.0 16 Q9HCM4,Q9HD47,Q9UM22,Q99996,P15924,Q14126,P14923,P16615 8 +Phagocytosis 0.3247846493550453 0.4497465003860099 0.6528932378916041 1.0 1.0 39 Q92614,Q9NWH9,P20339,P60953,Q9NX58,Q9BZG1 6 +Regulation of pattern recognition receptor signaling pathway 0.375389545636098 0.4494677026007742 0.6530943016586743 1.0 1.0 22 Q9NZM5,P41440,Q3LXA3 3 +Positive regulation of hematopoietic progenitor cell differentiation 0.7666566174253755 0.4482303544835664 0.6539869579588282 1.0 1.0 2 O43809 1 +Positive regulation of growth 0.269880182337289 0.4482069173776337 0.6540038709014526 1.0 1.0 55 O43909,Q13868,Q16539,P31749,P16989,P60953,Q9HCL2,Q9BSK2 8 +Regulation of neutrophil migration 0.3961736065289815 0.4472749059849291 0.6546765831648398 1.0 1.0 8 Q8NE86,O94813,Q07021 3 +Hydrogen peroxide metabolic process 0.3812053537960175 0.4469412449094336 0.6549174830810567 1.0 1.0 9 Q13162,P04179 2 +Negative regulation of cell substrate adhesion 0.3811537575519982 0.4467389041456498 0.6550635885638041 1.0 1.0 9 Q9P258,P42771,P63167,P61586,O75122 5 +Cellular detoxification of aldehyde 0.4404279454236252 0.445340199032714 0.656073921413336 1.0 1.0 5 P10768,Q8TC12,P11766 3 +Positive regulation of potassium ion transmembrane transporter activity 0.4403487970782297 0.4450609832440926 0.6562756840177015 1.0 1.0 5 P54709 1 +Regulation of hematopoietic progenitor cell differentiation 0.3668869852241789 0.4439742812861316 0.657061178400844 1.0 1.0 11 Q9Y5A9 1 +Peptidyl asparagine modification 0.3644973148655864 0.4432047183311373 0.6576176663791489 1.0 1.0 10 P46977,Q9Y673,P04844,P39656 4 +Positive regulation of gluconeogenesis 0.5283474065138754 0.4426635238309852 0.6580091297905759 1.0 1.0 3 P61964,Q16531 2 +Spliceosomal tri snrnp complex assembly 0.3665561974602954 0.4426387333469913 0.6580270637933305 1.0 1.0 11 O95400,O94906,Q6P2Q9,Q9Y312 4 +Macrophage differentiation 0.4393349189399869 0.4414901471737108 0.6588581929192141 1.0 1.0 5 P60953 1 +Response to hydrogen peroxide 0.3618239878217426 0.4409292672988295 0.6592642047868247 1.0 1.0 29 Q99720,P17655,P42574,Q9NWH9,P04179,P03915,P30405 7 +Regulation of postsynaptic membrane neurotransmitter receptor levels 0.3944427665357661 0.4406832926110786 0.6594422935672559 1.0 1.0 8 Q96RT1,Q9NQX3,Q15334,P61006,O60716,Q96QK1,Q14160 7 +Regulation of response to wounding 0.3737280428016598 0.4375857409498075 0.6616866095174296 1.0 1.0 19 Q13247,P10586 2 +Multicellular organism growth 0.3656030628818694 0.4371481585903362 0.6620039034749019 1.0 1.0 27 Q8TAF3,Q9HCL2,Q9BZK7,O15020 4 +Negative regulation of fat cell differentiation 0.4061030948811479 0.4323195025917989 0.665509214575049 1.0 1.0 7 O75962,P04179 2 +Regulation of glycoprotein metabolic process 0.3655715676643879 0.4308525367356853 0.6665755965131384 1.0 1.0 12 P62820,Q9BXS4 2 +Sodium ion transport 0.3658238562888521 0.4296136828114382 0.6674766821571105 1.0 1.0 26 Q9HD47,Q99653,Q9UHD1,P31749,P54709,P08195,Q16795 7 +Regulation of alternative mrna splicing via spliceosome 0.3469404877202967 0.4283305277645925 0.668410496145267 1.0 1.0 33 Q96T37,P31483 2 +Resolution of meiotic recombination intermediates 0.7588182092251985 0.4278515682032802 0.6687591898282348 1.0 1.0 2 Q02880 1 +Regulation of vascular associated smooth muscle contraction 0.7585167319867345 0.4270760290933156 0.6693239518209564 1.0 1.0 2 P61586 1 +Regulation of filopodium assembly 0.3645427497022393 0.426749260751277 0.6695619666375257 1.0 1.0 12 P62330,P60953 2 +Sensory organ morphogenesis 0.3691932562147878 0.4264165113577367 0.6698043721024356 1.0 1.0 23 Q16706,P63173,O95140,O14641,Q8NHU6,Q13308 6 +Estrous cycle 0.4710063066944512 0.426101711125424 0.6700337334010653 1.0 1.0 4 P08069 1 +Myeloid cell differentiation 0.2900619860925433 0.4253059402765939 0.6706136637557429 1.0 1.0 69 Q96T37,Q04760,Q16539,O00625,P60953,Q9NX58,Q8N5M9,P62805,Q9UII2 9 +Regulation of membrane potential 0.273282001103558 0.4243549426082559 0.6713069755206438 1.0 1.0 59 P30048,Q9UII2,O75083,Q9HD47,P09874,Q99996,Q07812,P04179,P51608,P31749,P54709,P28331,Q9H2U2,Q14126,Q9BSK2,Q9UJZ1,P14923 17 +Amino acid import across plasma membrane 0.4344181251790021 0.4243305142302341 0.6713247883823108 1.0 1.0 5 P08195 1 +Meiotic chromosome separation 0.4342749745659028 0.4238348836439004 0.6716862357492881 1.0 1.0 5 Q02880,P11388 2 +Protein peptidyl prolyl isomerization 0.3659947922728958 0.4232266876771328 0.6721298771656405 1.0 1.0 25 P26885,Q96BP3,P30405,Q9Y237,Q9H2H8,P45877 6 +Protein nitrosylation 0.7570093457943917 0.4232076510205756 0.6721437650755933 1.0 1.0 2 P04406 1 +Adipose tissue development 0.3666153988570216 0.422405330616066 0.6727291876851651 1.0 1.0 14 Q9BZK7 1 +Cellular respiration 0.3463828328386382 0.4218233879652716 0.673153933231162 1.0 1.0 105 P56134,O75438,P50213,O43676,P48047,P38117,P61586,Q96I99,Q99798,P30405,Q9UJZ1,Q9UDW1,P10515,P19404,Q8TCS8,Q02218,P08559,P28331,Q9NZM5,P14927,O14548,P20674,Q9BRT2,O75380,P08574,P03915,P36957,O95139,O43819,Q9BSK2,O95168,P04179,Q9P2R7,Q16795,O14949 35 +Growth hormone secretion 0.7564063913174406 0.4216646641341975 0.6732697999338135 1.0 1.0 2 P62820 1 +Ossification 0.2810810043385476 0.4205277485826068 0.6740999627233477 1.0 1.0 64 P22087,Q9H2U1,Q86V81,P62841,Q9NY93,P61586,Q9Y3A5,P20020,Q06124,Q9UBG0,O76021,P63173,Q9NR30,Q9H6W3,Q16539,P31749,Q9P2E9,P61604,Q9BZE4,Q15125,Q9NX62,Q9BQG0 22 +Negative regulation of mitochondrion organization 0.3672571220764266 0.4201557212986868 0.6743716990614583 1.0 1.0 15 P30405,P31749,P05141 3 +Arginine metabolic process 0.5208559155438477 0.4197673215861763 0.674655439479344 1.0 1.0 3 P16930 1 +Filopodium assembly 0.3642671102929242 0.4188681013075326 0.6753125307826009 1.0 1.0 13 P62330,P60953 2 +Axon development 0.3100015608767326 0.4178939938585199 0.6760246240376802 1.0 1.0 82 Q8N8S7,P11047,P10586,Q13740,O75962,P41440 6 +Regulation of fc gamma receptor signaling pathway involved in phagocytosis 0.7545975278866459 0.4170507569514383 0.6766412822859555 1.0 1.0 2 Q9UKG1 1 +Phosphatidylglycerol metabolic process 0.3600235721547142 0.4166647330251354 0.6769236535672265 1.0 1.0 11 P51608,Q9UJZ1,Q9HCL2,Q92604 4 +Development of primary female sexual characteristics 0.3650997761953633 0.4163724779054911 0.6771374644477217 1.0 1.0 14 P42574,Q9UI10,Q05086,Q07812 4 +Female sex differentiation 0.3650997761953633 0.4163724779054911 0.6771374644477217 1.0 1.0 14 P42574,Q9UI10,Q05086,Q07812 4 +Actin polymerization or depolymerization 0.2652933291636354 0.4157875402133004 0.6775654770677015 1.0 1.0 55 Q8N8S7,Q9UHB6,Q9Y281,P35080,Q9Y3C0,P62330,O15144,O15020 8 +Negative regulation of dna replication 0.3728266712964406 0.4146265875178053 0.6784152816196694 1.0 1.0 9 P54132 1 +Positive regulation of steroid metabolic process 0.4674540550199613 0.4146072463916977 0.6784294425780557 1.0 1.0 4 Q5SW96 1 +Positive regulation of cold induced thermogenesis 0.3645636500771219 0.4142491392488096 0.6786916577681437 1.0 1.0 14 P23786,O75175,P40939,O95140 4 +Lymphocyte migration 0.3643494539328789 0.4134023806400307 0.6793118307246815 1.0 1.0 14 P31749,Q9Y624 2 +Regulation of glycogen catabolic process 0.7530901416942894 0.4132231859548308 0.6794431022328027 1.0 1.0 2 P62140 1 +Inositol lipid mediated signaling 0.3668610688254299 0.4130061448222793 0.6796021116882787 1.0 1.0 22 Q07021,Q9NV70,Q05086,Q9UBF8,Q01970,P31749,Q8NEB9,Q9NZM5 8 +Asparagine metabolic process 0.518395657418579 0.4123569774081479 0.6800777921062078 1.0 1.0 3 Q7L266,Q9NQR4 2 +Pigment granule maturation 0.5180940892641748 0.4114524355479031 0.6807408116444429 1.0 1.0 3 O14617,Q9BXS5 2 +Pigment accumulation 0.5180940892641748 0.4114524355479031 0.6807408116444429 1.0 1.0 3 O14617,Q9BXS5 2 +Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 0.7509798010250093 0.4078913041716631 0.6833534771948189 1.0 1.0 2 P16989 1 +Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 0.7509798010250093 0.4078913041716631 0.6833534771948189 1.0 1.0 2 P16989 1 +Regulation of gtp binding 0.3988260884689785 0.4058861655754489 0.6848262434960812 1.0 1.0 7 Q9NWH9 1 +Mitochondrial rna catabolic process 0.411424563882699 0.4051844426688876 0.6853419396767262 1.0 1.0 6 Q8IYB8,Q8TCS8,Q12849 3 +Glucose import 0.358710604164859 0.4038626852386642 0.6863136973306951 1.0 1.0 12 Q06124,Q16539,P31749,P52789,Q9UKG1 5 +Liver regeneration 0.3693915819483754 0.4017044752795277 0.68790153055367 1.0 1.0 9 P62841,Q8TCS8 2 +Negative regulation of mrna splicing via spliceosome 0.3627733705684927 0.3985579899109004 0.6902189212970262 1.0 1.0 16 Q13247,Q9BTD8 2 +Mononuclear cell migration 0.3601699473366919 0.3982274295849338 0.6904625485583986 1.0 1.0 25 Q07021,Q5JRA6,P61586,Q9Y624,P31749,P60953,P39019,P78536 8 +External encapsulating structure organization 0.3566839578217089 0.397638895673029 0.6908963850794769 1.0 1.0 27 Q8NBJ5,P11047,O75122,O60568,P41440 5 +Regulation of cytoplasmic translation 0.3630565714787144 0.3967957294222788 0.6915181001970563 1.0 1.0 17 Q9Y5A9 1 +Negative regulation of oxidative stress induced neuron death 0.4616512722477448 0.3961068345706477 0.6920262165539957 1.0 1.0 4 Q15233,P35222 2 +Establishment of mitotic spindle localization 0.3583876068085805 0.3959262389184655 0.6921594435837921 1.0 1.0 13 P42858 1 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.4086618367087176 0.3955248317213291 0.6924555993811643 1.0 1.0 6 O95140 1 +Regulation of histone methylation 0.3242364705600005 0.3955117371864055 0.6924652612419002 1.0 1.0 37 O75367,Q12824,Q9Y3Y2,P46100 4 +Bone development 0.3578398560789588 0.3948982664102068 0.6929179694410128 1.0 1.0 26 P26373,Q7Z3C6,Q16539,P61586,Q7RTS9,Q9NX62,P50454,Q9Y3A5,Q15125 9 +Ncrna processing 0.4876350992621328 0.3945140357845982 0.6932015666998836 1.0 1.0 218 P22087,P55769,Q969Y2,Q2NL82,Q68CQ4,P62857,Q9BYD6,Q9NVH2,Q9Y3A5,Q8TCT8,Q9Y5A9,P46087,P62081,Q8TDN6,Q96B26,Q13868,Q9NR30,Q99848,O15213,P62847,Q99547,P62312,O75127,Q99575,Q96DE0,Q9NXG2,Q14137,Q9BSC4,O00541,P18077,P50914,Q9NX58,Q9H501,P39019,P82912,Q9NQ55,Q9Y4W2,Q8TDD1,O43709,P57678,Q9NZM5,P61353,Q13206,Q9H974,Q9H7B2,Q9GZR2,Q9Y2L1,Q96GQ7,Q5JTZ9,Q9Y3A2,Q8IY81,Q9Y237,Q8NEF9,Q9BVJ6,Q9ULW3,P62424,Q9NY93,Q8TEA1,Q5VV42,Q15046,O00567,P08708,Q13610,Q13601,Q8N201,P62753,Q96CB8,Q9NPF4,Q9NXH9,Q9Y6V7,Q9BV44,Q9Y3I0,Q8N5L8,O95478,Q9UJA5,Q6DKI1,Q5RKV6,Q9H583,P62841,Q9H0A0,Q9NVP1,O60832,O76021,Q12788,Q14684,Q9BYG3,Q9H0S4,Q9UNQ2,Q9Y2P8,Q9BZE4,Q9H9Y2,Q13895,Q06265 93 +Regulation of myotube differentiation 0.4254709049034605 0.3937995226061733 0.6937290569001886 1.0 1.0 5 Q16539 1 +Nucleoside bisphosphate metabolic process 0.2863726137044084 0.393766062966596 0.6937537621589704 1.0 1.0 44 P36957,P10515,Q02218,Q4G176,Q15120,Q8WVX9,Q9P2R7,O95563,Q96IU4,P08559,Q8WVC6,Q9HCL2,Q96I99,Q92947,Q03426,Q8TB61 16 +Positive regulation of membrane permeability 0.3558479919473821 0.3928676657052826 0.6944172243686029 1.0 1.0 12 P30405,P05141,Q9UII2 3 +Regulation of mitotic cytokinesis 0.511740558278968 0.3925912096929913 0.6946214329970655 1.0 1.0 3 Q9Y2S7 1 +Maintenance of cell number 0.3451596516174008 0.3896129067292976 0.6968228067251687 1.0 1.0 31 O60244,Q13503 2 +Positive regulation of translation 0.2762508296334067 0.3887266257022012 0.6974783839801091 1.0 1.0 64 Q9NYY8,Q9Y5A9,Q9BRT2,P16989,Q9BY77,Q7Z478,Q567V2 7 +Positive regulation of mrna 3 end processing 0.4238083956555968 0.3882292151507483 0.6978464148556704 1.0 1.0 5 O43809 1 +Histone phosphorylation 0.3606874008381371 0.3876558624282768 0.6982707230344041 1.0 1.0 22 Q9ULX6,O75367,Q99986,Q86Y07 4 +Transcription elongation from rna polymerase i promoter 0.4589540899723803 0.3876276757014184 0.6982915849810574 1.0 1.0 4 O15160 1 +Negative regulation of protein modification by small protein conjugation or removal 0.3269228434171417 0.3874176579595524 0.6984470333663848 1.0 1.0 36 P60866,Q96BK5,Q99653,P31689,P62841,P31749,P62081,Q9BZE4,Q04323 9 +Dna replication initiation 0.3597724907277294 0.3839764897362827 0.7009958727821337 1.0 1.0 22 Q7L590,Q8WTT2,Q9ULV3 3 +Regulation of extracellular matrix organization 0.4053051572824609 0.3839146631856831 0.701041697994955 1.0 1.0 6 O75122 1 +Telomere organization 0.2801772622004954 0.3824230079152598 0.7021476271136622 1.0 1.0 67 P46100,P54132,Q96BK5,P41440,Q15554,O60934,Q96SB8,Q96QC0,Q9H0A0,P62805,O60832 11 +Negative regulation of establishment of protein localization 0.3562661238926781 0.3819577739849284 0.7024926857100651 1.0 1.0 25 Q9UMY4,Q8N5M9 2 +Regulation of polysaccharide metabolic process 0.3783879758155968 0.3815808484253523 0.7027722919848336 1.0 1.0 8 P31749 1 +Protein localization to nucleoplasm 0.3544210617735238 0.3808356565306293 0.7033251993773655 1.0 1.0 13 Q9NZM5 1 +Regulation of microtubule based movement 0.4213213457124097 0.3799583062390043 0.7039763649991211 1.0 1.0 5 P57076 1 +Segmentation 0.3551195308798999 0.3777872729185285 0.705588629031672 1.0 1.0 14 Q9HCM4,Q9H488,P80723,O14641 4 +Biological process involved in interaction with symbiont 0.3493879895463933 0.3751553389948727 0.7075449428267637 1.0 1.0 28 P11498,P81605,Q12824 3 +Mitochondrial protein processing 0.4026750386751319 0.3749164074219649 0.7077226362808013 1.0 1.0 6 Q9UJZ1,Q9Y4W6,Q99797 3 +Protein o linked glycosylation 0.3554718499776028 0.3743567989133743 0.7081388795168251 1.0 1.0 15 O60762,Q6ZXV5,O95394,O60568,Q9H488 5 +Positive regulation of vasculature development 0.3579647535118576 0.3740393068743325 0.708375072523689 1.0 1.0 19 O75340,P05556,Q86UE4,O96013,P52789,Q9UGM6,P14923 7 +Autophagy of nucleus 0.4545440765206245 0.3739326819241442 0.7084544007035842 1.0 1.0 4 Q5MNZ6 1 +Inner mitochondrial membrane organization 0.3571420692065941 0.3735118652539173 0.7087675160834288 1.0 1.0 22 O75431,Q9NVH1,Q9Y4W6,Q9Y5J9,O60220,Q9BUR5,Q5HYI7,Q9Y5J7,O95202,Q53H12,P38646,Q9P0J0 12 +Regulation of peptidyl serine phosphorylation 0.3507334580253478 0.3724738061104836 0.7095401109619563 1.0 1.0 27 P35080,Q13610,Q99996,Q07812,P31749,Q96L73,P14174 7 +Phospholipid biosynthetic process 0.2601812978957526 0.3707054370706705 0.7108569402426883 1.0 1.0 56 Q969N2,O60762,Q96S52,P17655,Q92604,Q99653,Q9UHD1,Q8WVX9,Q9NRA0,P48651,Q9UBF8,P78356,Q9HCL2,Q8NEB9,Q9NX62,Q9NTJ5,Q03426 17 +Autophagosome lysosome fusion 0.5035775477689407 0.3689241129663193 0.7121842896354602 1.0 1.0 3 P78356 1 +Transcription by rna polymerase iii 0.3559553594972818 0.368846609629372 0.71224206089632 1.0 1.0 22 P62875,Q9NR30,O15160,Q8N122,O60264,Q12789,Q9NY93,Q9Y5Q8,Q9Y5Q9,Q8WUA4,Q9BQG0 11 +Histone h3 deacetylation 0.417550232471169 0.3675617170575799 0.7132000647753518 1.0 1.0 5 Q9H4L7,P23246,Q92769 3 +Error free translesion synthesis 0.7343985529092405 0.3671148902322585 0.713533320797433 1.0 1.0 2 Q9Y2S7 1 +Valine metabolic process 0.4172672279178729 0.3666385468452028 0.713888651307774 1.0 1.0 5 O15382 1 +Pyruvate metabolic process 0.304092712662442 0.366501915877558 0.7139905832547366 1.0 1.0 40 P10515,P09622,P04406,Q02218,Q15120,O95563,P11498,P08559,P23368 9 +Nadh regeneration 0.3873792270531376 0.3657457331697183 0.7145548168395892 1.0 1.0 7 P19367,P09104,P17858,P08237,P52789,P06733 6 +Mannosylation 0.3997370229826911 0.3649697750543522 0.7151339682953863 1.0 1.0 6 O60762,O75340,Q6ZXV5 3 +Positive regulation of peptidyl serine phosphorylation 0.3548286984890692 0.3644498855167424 0.7155220897697083 1.0 1.0 22 P31749,P35080 2 +Membrane protein proteolysis 0.349880403271667 0.3639566768266062 0.71589036074555 1.0 1.0 13 Q8TCT8 1 +Positive regulation of histone modification 0.2982684020292163 0.3634958216218026 0.7162345336470655 1.0 1.0 41 Q969T9,Q12824,Q9Y3Y2,Q49A26 4 +Substrate adhesion dependent cell spreading 0.3541118400433897 0.3616689539444212 0.7175994298462762 1.0 1.0 22 P62820,P11047,P60953 3 +Cell communication involved in cardiac conduction 0.3453123524823626 0.3611311127119399 0.718001435862617 1.0 1.0 11 P17612,Q14126,Q9HD47,P15924,P14923 5 +Cellular response to carbohydrate stimulus 0.3477948032096475 0.3604130195711703 0.7185382917379823 1.0 1.0 27 P55809,Q12824,Q15120,O95563,Q96ST3,Q8N5M9,P17480,P46734 8 +Monocyte chemotaxis 0.4150636591251765 0.3594850008020653 0.7192322965741775 1.0 1.0 5 O94813,P39019 2 +Positive regulation of cell cell adhesion 0.3432508161289166 0.3587626519764 0.7197726545441765 1.0 1.0 29 P31749,P41440,Q9HCL2 3 +Epithelial cell apoptotic process 0.3498775264376861 0.3583461229665126 0.7200843055926265 1.0 1.0 14 Q13247,P62330,P08069,O15446 4 +Regulation of dna replication 0.2527751127785745 0.3555115936780994 0.7222063609725611 1.0 1.0 53 P46100,P54132,P0CG13,Q7Z6E9,O60934,P60953,Q9ULV3,Q9HAF1,Q9BZE4 9 +Regulation of jnk cascade 0.3473382474607488 0.3546957854721509 0.7228175086290074 1.0 1.0 13 P31689,P60953,Q969S3 3 +Negative regulation of dendritic spine development 0.728971962616815 0.354214872531929 0.7231778585654756 1.0 1.0 2 Q05086 1 +Cardiac muscle cell action potential involved in contraction 0.3964187231589254 0.3538718454836744 0.7234349275818328 1.0 1.0 6 P14923,P15924,Q14126 3 +Regulation of pigmentation 0.7286704853783494 0.3535048301591442 0.7237100082863779 1.0 1.0 2 Q07812 1 +Negative regulation of actin filament depolymerization 0.3514921331446091 0.352784543771455 0.7242499719982545 1.0 1.0 17 Q9UHB6,O15020 2 +Dicarboxylic acid catabolic process 0.3834948169537563 0.3525475363026681 0.7244276750008332 1.0 1.0 7 Q4G176 1 +Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.3458219851204853 0.3524554295366714 0.7244967386411858 1.0 1.0 27 Q9BSC4,Q12788,Q2NL82,Q68CQ4,O15213,Q9Y2P8,Q13895,P82912,Q9H583 9 +Tissue morphogenesis 0.2862421888682166 0.3509643885173046 0.7256150649302577 1.0 1.0 74 Q9HCM4,Q96T37,Q9NWH9,O14641,O75122,P60953,O60568 7 +Nucleobase containing compound transport 0.3335226610882589 0.3489251568956817 0.727145498239814 1.0 1.0 105 P05141,O43808,O15439,Q9HAU5,Q86V81,P37198,Q9UKX7,P49790,Q9Y3Y2,Q9BY77,Q86U42,P41440,Q86W42,O00159,Q8TCS8,Q9ULX6,Q9UN86,Q08722,Q9Y6M1,Q5SRE5,Q9BTX1,Q8TB61,O75152,P78406,Q8NFH5,Q99700,Q6P6C2,Q8NI27,Q9BSK2,Q8TEM1 30 +Nucleoside diphosphate catabolic process 0.4960834340876009 0.3477808583411469 0.7280047661870395 1.0 1.0 3 Q9BW91 1 +Ribonucleoside diphosphate catabolic process 0.4960834340876009 0.3477808583411469 0.7280047661870395 1.0 1.0 3 Q9BW91 1 +Regulation of mitochondrial fission 0.3391934629274709 0.3473412043030732 0.7283349988500809 1.0 1.0 10 Q9NX47 1 +Negative regulation of protein localization to cell periphery 0.3391089496660878 0.3470421668070786 0.7285596405259407 1.0 1.0 10 Q9NQ48,Q13492,Q9BXS4 3 +Pigment granule organization 0.4109837054918465 0.3464041760387767 0.7290389871453868 1.0 1.0 5 O43747,P78537,O14617,Q9BXS5 4 +Single stranded viral rna replication via double stranded dna intermediate 0.38132953145536 0.3452874424630066 0.7298782862906334 1.0 1.0 7 Q02880,Q12824,Q9Y6X9 3 +Regulation of cytokinesis 0.3469483765993347 0.3447658744175061 0.730270390124147 1.0 1.0 25 O95235,Q9Y2S7,Q16513,P37198,P61586,P60953,Q9H8V3,Q7Z7K6,Q8NEB9,P08069 10 +Negative regulation of cholesterol metabolic process 0.7244498040397904 0.3436383775712124 0.7311182592771537 1.0 1.0 2 O75477 1 +Germ cell proliferation 0.7241483268013145 0.3429389579573681 0.7316443827596153 1.0 1.0 2 Q13162 1 +Epithelial cell proliferation 0.2490138289801519 0.34256143316123 0.7319284201953673 1.0 1.0 52 Q13247,P11047,P31749,P60953,Q8TAF3,P78536 6 +Regulation of mrna polyadenylation 0.3436333865646578 0.3414478210409895 0.7327664797726843 1.0 1.0 13 P09012 1 +Negative regulation of receptor mediated endocytosis 0.3371404181108871 0.3401191021079609 0.7337668370047725 1.0 1.0 10 P62330,Q99700 2 +Positive regulation of interleukin 6 production 0.3653416324308773 0.3364872882101916 0.7365034358570508 1.0 1.0 8 Q7Z434,P10809,Q06124,Q9NRA0,Q92974 5 +Neuron projection extension 0.3117525144057713 0.3361263918795842 0.736775557243776 1.0 1.0 37 Q13740 1 +Response to molecule of bacterial origin 0.2927774677759679 0.3359376720360704 0.7369178680566522 1.0 1.0 41 P17655,Q16539,P04179,P31749,Q02952,P14174,P46734,P78536 8 +Vascular endothelial growth factor receptor signaling pathway 0.3908964701718013 0.3357319950658916 0.7370729762601069 1.0 1.0 6 Q16539 1 +Epiboly 0.3358107816104609 0.3354891469686611 0.7372561303007807 1.0 1.0 10 O75122 1 +Rrna transport 0.7208320771781598 0.3352926615939151 0.7374043288785854 1.0 1.0 2 Q8TCS8 1 +Insulin metabolic process 0.7205305999397066 0.3346018653537134 0.7379254376001623 1.0 1.0 2 Q96HE7 1 +Clathrin coat assembly 0.3647477235338397 0.3345015654724788 0.7380011097909918 1.0 1.0 8 P53680 1 +Negative regulation of protein binding 0.3412423618029117 0.334422068129483 0.7380610891144221 1.0 1.0 27 P31749,P10586 2 +Positive regulation of establishment of protein localization to telomere 0.3351465699607177 0.3331903433315196 0.7389906069920351 1.0 1.0 10 Q99832,Q9BUR4,P48643,P40227,P78371,P17987,P49368,P50990,O60832 9 +Regulation of establishment of protein localization to chromosome 0.3351465699607177 0.3331903433315196 0.7389906069920351 1.0 1.0 10 Q99832,Q9BUR4,P48643,P40227,P78371,P17987,P49368,P50990,O60832 9 +Establishment of protein localization to telomere 0.3351465699607177 0.3331903433315196 0.7389906069920351 1.0 1.0 10 Q99832,Q9BUR4,P48643,P40227,P78371,P17987,P49368,P50990,O60832 9 +Regulation of epithelial cell differentiation 0.3466242757459961 0.3330726716994969 0.7390794275660093 1.0 1.0 18 Q9P0M6,Q13247,Q9Y624 3 +Regulation of lipid kinase activity 0.4064515243605119 0.332129240455089 0.739791671463651 1.0 1.0 5 P60953 1 +Cellular response to molecule of bacterial origin 0.3362983242451728 0.3306588262211422 0.7409022062817452 1.0 1.0 29 P31749,P17655,P46734,P14174 4 +Response to progesterone 0.3753738909098398 0.3256861952199592 0.7446617898801302 1.0 1.0 7 Q969T9,Q05086 2 +Protein localization to extracellular region 0.2768645256776486 0.3250450900136213 0.7451469460327342 1.0 1.0 71 Q92930,Q92614,P62330,Q9BRT2,Q8NE86,P51153,Q8N5M9 7 +Regulation of homotypic cell cell adhesion 0.4377435549648087 0.3237782176271176 0.7461059484363037 1.0 1.0 4 Q9Y624 1 +Cytoplasmic translational initiation 0.3442246730026722 0.3233271348514324 0.746447506036628 1.0 1.0 21 Q9Y5A9 1 +Positive regulation of dna binding transcription factor activity 0.2792459858873958 0.3229858189208469 0.7467059818488295 1.0 1.0 43 P31749,Q9H6R0,P41440,O14641 4 +Lactate metabolic process 0.3737922705313984 0.3205732881347233 0.7485337830310503 1.0 1.0 7 Q99497,P00338,P04637,Q16775,O75746,P07195 6 +Cellular modified amino acid catabolic process 0.3603909976971076 0.3201204612774334 0.748877015310851 1.0 1.0 8 P30038 1 +Viral rna genome replication 0.3399630124303776 0.3186488214846044 0.7499928275174574 1.0 1.0 15 P11388,Q12824,Q9Y6X9,Q02880,P20339,P60953 6 +Rrna 5 end processing 0.4018888430171083 0.3180377431141267 0.7504563072363193 1.0 1.0 5 Q12788 1 +Dna methylation 0.3422950360716882 0.3178468434252485 0.7506011158689851 1.0 1.0 18 P51608,Q9NPF5,P46100 3 +Histone h3 k4 methylation 0.3384352036959525 0.3177454352457543 0.7506780435064964 1.0 1.0 26 P10412,O75367,P16403,P16402,Q15291,Q6UXN9 6 +Positive regulation of endoplasmic reticulum unfolded protein response 0.4849156055439336 0.3173624312120943 0.7509686104268656 1.0 1.0 3 Q07812 1 +Positive regulation of ire1 mediated unfolded protein response 0.4849156055439336 0.3173624312120943 0.7509686104268656 1.0 1.0 3 Q07812 1 +Neuroblast proliferation 0.3447952261558184 0.3152445456583403 0.7525759859537924 1.0 1.0 9 Q92974,P35222,P61026 3 +Ameboidal type cell migration 0.2843468392604217 0.3145284144930376 0.7531197390205413 1.0 1.0 77 Q9HCM4,O75340,P35080,P62330,Q9NWH9,Q16539,P31749,O75122,P60953,P51153,Q7Z7K6,P46734,P78536 13 +Antibacterial humoral response 0.7114862827856443 0.3142177728965017 0.753355644979737 1.0 1.0 2 P04439 1 +Chromatin remodeling 0.2994725148425885 0.312954541038776 0.7543151994957746 1.0 1.0 87 P10412,O75367,P46100,Q12824,P16403,P16402,Q9P0M6,Q9GZN1,P17096,Q96T23,Q5SSJ5,Q7Z7K6,Q92522,Q9NPF5,P62805,P07305 16 +Positive regulation of reproductive process 0.383654174513899 0.3125880780074769 0.7545936369192798 1.0 1.0 6 Q92769,Q07021,Q9H6S0 3 +Mitotic sister chromatid cohesion 0.3349590917160181 0.3116172777507505 0.755331401892525 1.0 1.0 13 P0CG13,Q9GZZ1,O75367,P46100 4 +Amino acid import 0.3571335042557352 0.309584677504251 0.7568768097967158 1.0 1.0 8 P08195,Q96NB2 2 +Negative regulation of protein localization to membrane 0.3303572917748431 0.3092444023248446 0.7571356199012591 1.0 1.0 11 Q9NQ48,Q13492,Q9BXS4 3 +Regulation of hormone levels 0.2689293654097208 0.3079472326044912 0.7581224845800636 1.0 1.0 68 Q92930,P55809,O15382,Q9Y394,Q9BRT2,P82094,Q8NE86,Q8N5M9,P62820,Q8NBQ5,O75787 11 +Regulation of mitochondrion organization 0.258260297898307 0.3078510138152152 0.7581957019264429 1.0 1.0 46 P05141,Q96A26,Q07812,P31749,Q8NE86,Q9NX47,P42858,P30405,Q9UII2 9 +Brown fat cell differentiation 0.3564663058565481 0.3074500065685757 0.7585008703161451 1.0 1.0 8 Q02252,Q00839,Q16539,Q96HE7 4 +Mitochondrial genome maintenance 0.3422699795701615 0.3070122165731648 0.7588340735097949 1.0 1.0 9 Q9BQP7,Q9BSK2 2 +Cardiac muscle cell action potential 0.3333604108111102 0.3063056970955746 0.7593719019051199 1.0 1.0 13 Q14126,Q9HD47,Q99996,P15924,P14923,P16615 6 +Organelle transport along microtubule 0.3250540792106793 0.3059464114999541 0.7596454478688124 1.0 1.0 31 P62820,P60953,P42858 3 +Inositol metabolic process 0.4801518891493247 0.3047998068255449 0.7605186286606593 1.0 1.0 3 P51608 1 +Positive regulation of peptidyl lysine acetylation 0.3328911152067269 0.3047576769034353 0.7605507179347468 1.0 1.0 13 Q969T9,Q49A26 2 +Regulation of lymphocyte migration 0.3266507120597962 0.3046293780660563 0.760648442384757 1.0 1.0 10 P31749,P78536,Q5JRA6 3 +Microtubule nucleation 0.3377166051368486 0.3043853674446174 0.7608343143411023 1.0 1.0 17 O75122,Q99996,Q9HD47 3 +Integrin activation 0.4798186009958953 0.3039303499766407 0.7611809549199773 1.0 1.0 3 Q15058 1 +Oxaloacetate transport 0.7060596924932162 0.3023081137889544 0.7624171936326256 1.0 1.0 2 Q9UBX3 1 +Succinate transmembrane transport 0.7060596924932162 0.3023081137889544 0.7624171936326256 1.0 1.0 2 Q9UBX3 1 +Histone h2a ubiquitination 0.3800181104738934 0.3012546528099243 0.7632203173707433 1.0 1.0 6 Q96FW1,Q16531,P63208,Q14669,Q13620 5 +Cellular response to biotic stimulus 0.3036613301653316 0.3011316302384719 0.7633141223406614 1.0 1.0 37 P31749,P17655,P46734,P14174 4 +Intrinsic apoptotic signaling pathway 0.2879188555964764 0.3011279366694676 0.7633169387485499 1.0 1.0 81 Q8N2F6,Q9BVC6,P42574,P31689,Q7LG56,Q07820,P04179,Q969S3,P31749,P16989,P62081,O60934,Q8IXB1,P30405,P14174,Q9P0J0 16 +Establishment or maintenance of bipolar cell polarity 0.3373557699052337 0.3010412124833359 0.7633830682851919 1.0 1.0 18 Q14168,O75083,P57105,P61586,P60953,Q13308,Q13418 7 +Positive regulation of ion transport 0.2683186607631703 0.2976224999923751 0.7659912998739407 1.0 1.0 44 Q99653,Q9UHD1,Q99996,Q07812,P31749,P51809,P54709,P42858,P14174 9 +Srp dependent cotranslational protein targeting to membrane signal sequence recognition 0.7033463973469987 0.2964451266490744 0.7668901670772867 1.0 1.0 2 P61011 1 +Retina development in camera type eye 0.3358133498901162 0.2959187952895501 0.767292096993359 1.0 1.0 18 Q16706,P11047 2 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.3238682535380165 0.2956225285538921 0.7675183669272552 1.0 1.0 10 P31749 1 +Positive regulation of protein localization to nucleus 0.2889831266395074 0.2953905950210899 0.7676955170307187 1.0 1.0 40 Q9NW64,Q96BK5,Q16539,P31749,Q9NPF5 5 +Positive regulation of cell adhesion 0.2537780261998417 0.29537679639846 0.7677060567579275 1.0 1.0 60 Q9HCM4,P31749,Q9Y624,P60953,Q9HCL2,P41440 6 +Positive regulation of telomerase rna localization to cajal body 0.3280919262171157 0.295109896445145 0.7679099299533148 1.0 1.0 12 Q99832,P50991,P48643,P40227,P78371,Q9NX24,P17987,P50990,Q9Y265,P49368,O60832 11 +Actin filament depolymerization 0.3357441308745723 0.2949768468508211 0.7680115667152199 1.0 1.0 22 P28289,Q9UHB6,O15020,Q9Y281 4 +Aminoacyl trna metabolism involved in translational fidelity 0.3236497897062737 0.2949227489410242 0.7680528933211854 1.0 1.0 10 Q9BW92,Q15031,Q5ST30,Q5JTZ9,P41252 5 +Phosphatidylinositol metabolic process 0.3303421729106331 0.2940433424894002 0.7687247840214861 1.0 1.0 27 Q969N2,O60762,Q96S52,Q92604,Q9UBF8,Q01970,P78356,Q9NX62,Q9NTJ5 9 +Collagen fibril organization 0.3653113605362943 0.2938413286573856 0.7688791527015764 1.0 1.0 7 O60568 1 +Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.4750092932358574 0.2915241585389468 0.7706504700124586 1.0 1.0 3 P62081 1 +Viral translational termination reinitiation 0.3766978569272589 0.2910775396747916 0.7709920172951754 1.0 1.0 6 P55884,P56537,Q14152,O75821,O15371 5 +Cellular response to lipoprotein particle stimulus 0.3763718249215152 0.290087173956717 0.7717495478280538 1.0 1.0 6 P31749 1 +Protein methylation 0.2620520976771689 0.2887671498145772 0.7727595723055929 1.0 1.0 66 Q15022,P10412,O75367,Q12824,P46100,P16403,P16402,P22087,Q13610,O60725,Q15291,P51608,P62318,Q96L73,Q9Y3Y2,Q6UXN9,P22061 17 +Cilium movement 0.3362852071503058 0.2880122034935464 0.7733373972575575 1.0 1.0 9 P82094 1 +Positive regulation of double strand break repair via homologous recombination 0.3317757229152553 0.2878325602426922 0.7734749121117388 1.0 1.0 16 P61160,P09874,Q9UBU8,Q9HAF1,Q9NPF5,Q8TAF3 6 +Negative regulation of defense response to virus 0.3632598754908449 0.2875523349203331 0.7736894355870567 1.0 1.0 7 Q3LXA3 1 +Tetrapyrrole biosynthetic process 0.3257131071022288 0.2875277649522619 0.7737082456858262 1.0 1.0 12 P22830,Q5T440,Q9UII2 3 +Organic acid transmembrane transport 0.3266092598837755 0.287013787095075 0.774101763592508 1.0 1.0 28 P31749,P41440,P08195,O60831 4 +Ruffle assembly 0.3271260453001542 0.2861609429790566 0.7747548563996927 1.0 1.0 13 P35080 1 +Trachea development 0.4235294117647078 0.2840181745421538 0.7763964526608218 1.0 1.0 4 P28482,P35222,P27361 3 +Trachea formation 0.4235294117647078 0.2840181745421538 0.7763964526608218 1.0 1.0 4 P28482,P35222,P27361 3 +Trachea morphogenesis 0.4235294117647078 0.2840181745421538 0.7763964526608218 1.0 1.0 4 P28482,P35222,P27361 3 +Er overload response 0.3901629450814657 0.2831631224975744 0.7770517959010852 1.0 1.0 5 Q96A33,P49841,Q9UM00,O76024 4 +T cell migration 0.3198742967745165 0.2830009066620986 0.7771761419877086 1.0 1.0 10 Q9Y624 1 +Dicarboxylic acid metabolic process 0.2759833956916621 0.2823999332896181 0.7776368661410169 1.0 1.0 42 P36957,P00505,Q02218,Q4G176,Q8TD30,P34896,P41440,Q9P2R7,P30038,P23368 10 +Transcription initiation from rna polymerase ii promoter 0.3303924337050617 0.2813784661828193 0.7784201326911826 1.0 1.0 24 O60244,Q9ULK4 2 +Meiotic cell cycle 0.2460018745422239 0.2800532190077015 0.7794366749002031 1.0 1.0 57 P46100,P61160,Q02880,Q5VUA4,Q9Y5A9,Q9H2V7,O60934,O60216,O95347,Q9UH99,Q9BTX1,O94901,Q9NQS7 13 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.3280581782181061 0.2796783548493046 0.7797242862039204 1.0 1.0 15 Q9NZM5,Q9NUD5,Q9H078,Q3LXA3 4 +Positive regulation of protein glycosylation 0.4702059940179897 0.2793984936956631 0.779939026930891 1.0 1.0 3 Q99653 1 +Meiotic cell cycle process 0.2801830048685492 0.278601048395703 0.7805510080492699 1.0 1.0 41 Q9UNM6,P46100,P61160,Q02880,Q9Y5A9,O60216,O95347,Q9BTX1,O94901,Q9NQS7 10 +Homeostasis of number of cells 0.2501317645750152 0.2767293900261836 0.7819879028432464 1.0 1.0 60 Q16539,P31749,P62847,Q9NX58,Q9HCL2,P14174,Q8TAF3 7 +Regulation of protein dephosphorylation 0.3194606945283853 0.2764830941197314 0.7821770427187309 1.0 1.0 30 Q86XL3,Q12972,P42858,Q5H9R7,Q15435 5 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.3289426075964775 0.2759807914821501 0.7825628196855425 1.0 1.0 17 P31749,Q07820,P04179 3 +Cell substrate adhesion 0.2417185301849968 0.274620733291727 0.7836076356999484 1.0 1.0 55 Q9HCM4,P11047,Q9Y2S7,O75122,P60953,P62820 6 +Regulation of hemopoiesis 0.2686819553598442 0.273742923876297 0.7842821887230045 1.0 1.0 43 Q96T37,P62805 2 +Response to increased oxygen levels 0.3454044869914436 0.2732424723228848 0.7846668335216214 1.0 1.0 8 Q8N511 1 +Myotube differentiation 0.327009765034312 0.2728365771109514 0.7849788413809276 1.0 1.0 16 P17655,P41440 2 +Telomere maintenance 0.2585130213961524 0.2714062705238024 0.7860785798010934 1.0 1.0 66 P46100,P54132,Q96BK5,P41440,Q15554,O60934,Q96QC0,Q9H0A0,Q96SB8,O60832 10 +Regulation of protein localization to nucleus 0.2440741162575249 0.2704138268699102 0.7868419039082695 1.0 1.0 57 Q9NW64,Q13148,P09874,Q99653,Q9UHD1,Q96BK5,Q16539,P31749,Q96ST3,Q9H8V3,Q13895,Q9NPF5,O60832 13 +Regulation of reactive oxygen species biosynthetic process 0.3303037419808067 0.2697572081916789 0.7873470456107414 1.0 1.0 9 P61586,Q9BSK2,P04179 3 +Mature ribosome assembly 0.3853456758016107 0.2694166439064696 0.7876090795388038 1.0 1.0 5 Q9Y3A5 1 +Alpha amino acid metabolic process 0.2688723933437378 0.2689477521725598 0.7879698893599332 1.0 1.0 73 A1L0T0,P00505,Q96C36,Q9HCC0,P30038,P26440,Q06210,P51608,O60568,Q92947,P52758,Q8TD30,P78330,Q9Y617,P25325,P36957,P22033,O15382,Q96RQ3,P34896,O60725,P32322 22 +Regulation of protein localization to nucleolus 0.3849780442498917 0.2683818690032223 0.7884053941899849 1.0 1.0 5 Q13895,Q96BK5 2 +Positive regulation of stress activated protein kinase signaling cascade 0.3149799769940063 0.2680356322030107 0.7886718913562538 1.0 1.0 10 P60953 1 +Platelet activation 0.3242658782479141 0.2679900861801474 0.7887069498005947 1.0 1.0 15 Q9BWH2,O00186,Q14344,Q16539,Q9Y624 5 +Response to ph 0.3687106263197187 0.2672869475603877 0.7892482356415096 1.0 1.0 6 Q99653 1 +Chromosome organization involved in meiotic cell cycle 0.3272759450797629 0.2672464238457385 0.7892794344609699 1.0 1.0 19 P46100,Q92878,O60216,Q6IBW4,O95347,Q9BTX1,O94901 7 +Development of primary sexual characteristics 0.3024680585581915 0.2671533337691529 0.789351104898103 1.0 1.0 35 Q13162,P46100,Q14151,P80723,P42574,P82094,Q9UI10,P16989,P51153,Q05086,Q8TAF3 11 +Negative regulation of actin filament polymerization 0.3272541461897501 0.2664906294447814 0.7898613751902259 1.0 1.0 21 O15020 1 +Positive regulation of heart growth 0.3842326656274166 0.2662901261307678 0.7900157768680807 1.0 1.0 5 Q16539 1 +Nucleoside bisphosphate catabolic process 0.4644603447819466 0.2652491267852755 0.7908175520911549 1.0 1.0 3 O00154 1 +Methylation 0.3295404091949223 0.2644726272132607 0.7914157544403704 1.0 1.0 115 Q96T37,O75367,Q12824,P16403,P22087,P16402,Q969Y2,Q96L73,Q8TEA1,Q9Y3Y2,Q15022,P10412,Q13610,P46087,O43709,Q9NPF5,Q9NXH9,Q86VU5,Q9UNQ2,Q9UJA5,P46100,O60725,Q8IY81,P22061 24 +Snrna metabolic process 0.3251849119762149 0.2644663680228361 0.7914205769161402 1.0 1.0 24 Q13868,Q5RKV6,Q8N201,Q9NVH2,Q06265,O60832 6 +Negative regulation of cell adhesion mediated by integrin 0.6879710581851057 0.264403970613514 0.7914686522590884 1.0 1.0 2 Q06124 1 +Positive regulation of systemic arterial blood pressure 0.6879710581851017 0.2644039706135057 0.7914686522590948 1.0 1.0 2 P61586 1 +Regulation of bicellular tight junction assembly 0.3549726224607301 0.2628741921092609 0.7926475486400588 1.0 1.0 7 Q9Y624 1 +Regulation of sodium ion transport 0.3259852476743703 0.2625642880361132 0.792886428501131 1.0 1.0 20 Q9HD47,Q99653,Q9UHD1,P31749,P54709 5 +Nuclear export 0.2894472905372729 0.2595739407715737 0.7951924397076489 1.0 1.0 88 Q9NW64,Q9NVU7,O75152,Q99653,Q9ULX6,Q86V81,P62841,Q9Y3Y2,Q6P6C2,Q8NI27,Q86W42 11 +Lipoprotein biosynthetic process 0.3198154426037856 0.2588679183203292 0.795737152092117 1.0 1.0 14 Q969N2,Q5MNZ6,Q96S52 3 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.3113581970895324 0.2569399033106037 0.797225165981233 1.0 1.0 31 Q9H9E3,P42858,Q96JB2 3 +Histone h3 k14 acetylation 0.3398141366878711 0.2568292676349035 0.7973105754016403 1.0 1.0 8 Q969T9 1 +Establishment of rna localization 0.296093882324203 0.2565526856906003 0.7975241039747145 1.0 1.0 93 Q9HAU5,Q86V81,P37198,Q9UKX7,P49790,Q9Y3Y2,Q9BY77,Q86U42,P41440,Q86W42,O00159,Q8TCS8,Q9ULX6,Q9UN86,Q9Y6M1,Q5SRE5,Q9BTX1,O75152,P78406,Q8NFH5,Q99700,Q6P6C2,Q8NI27,Q8TEM1 24 +Negative regulation of cartilage development 0.6837503768465465 0.2559667742779038 0.7979764931038629 1.0 1.0 2 Q06124 1 +Negative regulation of chondrocyte differentiation 0.6837503768465465 0.2559667742779038 0.7979764931038629 1.0 1.0 2 Q06124 1 +Regulation of core promoter binding 0.6837503768465393 0.2559667742778889 0.7979764931038744 1.0 1.0 2 Q00403 1 +Lens morphogenesis in camera type eye 0.6837503768465388 0.2559667742778883 0.7979764931038749 1.0 1.0 2 Q8NHU6 1 +Lung associated mesenchyme development 0.6837503768465373 0.2559667742778849 0.7979764931038775 1.0 1.0 2 Q13308 1 +Developmental induction 0.6837503768465327 0.2559667742778765 0.797976493103884 1.0 1.0 2 Q96C57 1 +Dicarboxylic acid biosynthetic process 0.3525572486165482 0.255905605923858 0.7980237258273 1.0 1.0 7 P00505 1 +Cardiac conduction 0.320863831061083 0.2543456516447495 0.7992285341932606 1.0 1.0 16 P20020,P17612,Q9HD47,Q99996,P15924,Q14126,P14923,P16615 8 +Positive regulation of type i interferon production 0.322534834459719 0.2520887619356465 0.8009724561977978 1.0 1.0 21 Q9NUD5,P41440 2 +Histone h3 k9 modification 0.3200174529106544 0.2518748712293057 0.8011377833735871 1.0 1.0 16 P51608,Q12824,P46100 3 +Protein kinase b signaling 0.311720007804109 0.2504929506338597 0.8022061555522026 1.0 1.0 30 P31749,Q9NZM5,Q9NWH9 3 +Negative regulation of protein containing complex disassembly 0.3136008897318801 0.2498540987311965 0.8027001814292405 1.0 1.0 29 Q9UHB6,O75122,O15020,Q8WWK9 4 +Negative regulation of small gtpase mediated signal transduction 0.3131863496217073 0.2498164939332376 0.8027292637791312 1.0 1.0 12 Q9NWH9 1 +Pyramidal neuron differentiation 0.4103929464010574 0.2496194523927805 0.8028816538797467 1.0 1.0 4 Q02218 1 +Exit from mitosis 0.3146196177438548 0.248556721117046 0.8037036894887937 1.0 1.0 13 P50748,P83731,O43633,O75122 4 +Mrna transcription 0.3364542434309872 0.2472556815657505 0.8047103550439667 1.0 1.0 8 O00203,Q7KZ85,Q15648,P04637,Q12800,P17844,Q09161 7 +Positive regulation of protein serine threonine kinase activity 0.2999122284863497 0.2467131664104584 0.8051302161698917 1.0 1.0 34 P31749,P14174,P78536,O14641 4 +Histone h3 acetylation 0.3181896586544902 0.246602094780247 0.8052161832096281 1.0 1.0 16 Q12824,Q9NRA0,Q969T9,Q96ST3,Q9HAF1 5 +Organonitrogen compound biosynthetic process 0.241436212637406 0.2462576523132592 0.8054827891990768 1.0 1.0 601 Q7Z7F7,Q5T653,P00505,P32321,P61513,P82914,P48047,Q16775,Q9UI10,Q8N3C0,P62857,Q8WVC6,Q9UGM6,Q9UJZ1,Q9NYY8,O43909,Q07021,Q96JB2,Q9Y5A9,P48651,P46776,P62081,O60568,Q96B26,Q7Z478,Q92879,Q7Z4H8,Q9BUT1,Q9BW92,P17655,Q13868,Q9UHD1,Q9BRT2,P31749,P62847,P82675,Q8N983,P46977,Q5ST30,P47914,Q14165,P34896,Q9BT22,Q9UKZ1,Q9NX20,Q9P2R7,P62244,Q9UIJ7,A1L0T0,P04406,P09874,P18077,Q9Y3U8,Q9BXS4,P50914,P62701,P62280,P61586,Q9Y3D3,P39019,Q8NEB9,P82912,P31483,Q6UB35,Q96S52,Q99653,Q9NRA0,Q9P0L0,Q9Y285,Q9Y6M1,Q9H6R0,Q8WU90,Q8TB61,Q5T160,Q16706,P15531,O75175,P52758,P09622,Q9BSH4,P61247,Q5MNZ6,P61353,P16989,O43324,P84098,O15382,Q9Y673,P61313,Q969N2,P04844,Q02878,P62424,Q9UHA3,Q5VV42,Q567V2,Q13724,O75340,Q6ZXV5,Q8TCS8,O95563,P08559,Q15031,Q13148,O95394,P36578,P62910,P83881,P62899,Q9H488,Q9UII2,P83731,P56134,P22830,P62269,P62750,P62841,Q9BY77,Q9H0A0,O60762,P10515,Q15056,P62277,Q96EY7,Q9NP81,Q92947,Q5T440,P26373,P63173,Q4G176,Q15120,Q9BY44,Q9P2E9,Q9Y2R9,P39023,P32969,P60866,P62917,Q96RP9,Q99700,Q06265 141 +Mitochondrial cytochrome c oxidase assembly 0.361269782045073 0.2460320973521075 0.805657385918664 1.0 1.0 6 Q9BSH4 1 +Positive regulation of cytoskeleton organization 0.232502009477235 0.245711270218303 0.8059057472470175 1.0 1.0 53 Q9Y281,O75083,P35080,Q9NWH9,Q99996,P37198,P62330,O15144,P51608,P60953,Q9Y613 11 +Negative regulation of endocytosis 0.3111634310938425 0.2440828272126788 0.8071666722844499 1.0 1.0 12 P62330,Q99700 2 +C4 dicarboxylate transport 0.3482945197209007 0.2438595994777906 0.8073395596215935 1.0 1.0 7 Q9UBX3 1 +Nitrogen compound transport 0.193186030266408 0.2437005151345708 0.807462774376807 1.0 1.0 592 Q9NW64,Q92614,P53365,O60831,O15439,Q9UMY4,O43808,Q86V81,Q9Y3C0,Q15286,Q99584,Q9Y3Y2,Q9BY77,Q8N5M9,Q9H9E3,P41440,Q86W42,O75695,O75340,P20338,O00159,Q9NVU7,Q8TCS8,O95140,O95391,Q99653,Q96JB2,Q9NP72,Q9ULX6,Q07820,O95563,Q9Y4P1,Q9UJY5,Q8NE86,P60953,P51153,O14828,Q9NPF5,Q5VZ89,Q9BTX1,Q8TB61,Q9NS69,P55809,O60826,Q03518,Q9HD47,Q13148,P51148,Q9BRT2,Q16539,P53680,P31749,P20339,Q5HYI7,Q9BZG1,Q9BZL1,Q92930,Q9NVJ2,O75152,P62330,O60725,Q9Y2D4,Q07960,O60220,Q96QC0,Q8NFH5,Q6P6C2,P61019,Q8NI27,P08195,Q9BSK2,P62820,Q9P0J0,Q9UII2 74 +Hemostasis 0.3184028682513739 0.2436520427667876 0.8075003183731826 1.0 1.0 24 Q9Y624,Q9UIJ7 2 +Antigen processing and presentation 0.3174915923592714 0.2435817923223534 0.807554731241757 1.0 1.0 25 Q9NVJ2,Q92930,Q03518,Q15286,P10321,Q9BZG1,P20338 7 +Regulation of cell division 0.3046871920877704 0.2434409361271021 0.8076638349882701 1.0 1.0 32 O95235,P54132,Q9Y2S7,Q16513,P37198,P61586,P60953,Q9H8V3,Q7Z7K6,Q8NEB9,P08069,Q9NR09 12 +Cellular macromolecule biosynthetic process 0.2938199489934761 0.2431324793591118 0.8079027710829485 1.0 1.0 590 Q7Z7F7,Q5T653,P61513,Q86V81,P82914,Q9UI10,Q8N3C0,P62857,Q9ULV3,Q9UGM6,P41440,Q9UJZ1,Q9NYY8,O43909,Q07021,Q96JB2,Q9Y5A9,P46776,P62081,O60568,Q96B26,Q7Z478,Q92879,Q7Z4H8,Q9BQP7,Q9BW92,Q13868,Q9NR30,Q9BRT2,P31749,P62847,P82675,Q8N983,P54132,Q96BK5,P47914,Q14165,P34896,Q9UKZ1,Q9Y3U8,Q9BXS4,Q15554,Q9Y3D3,Q7L590,P82912,P31483,Q96S52,Q99653,P60953,Q9H6R0,Q8WU90,Q5T160,Q16706,O75175,Q9Y2S7,Q9BSH4,Q5MNZ6,P61353,P16989,O43324,P84098,P62140,P46100,Q9Y673,P61313,Q969N2,P04844,Q02878,P62424,Q9NY93,Q9UHA3,Q5VV42,Q567V2,Q13724,O75340,Q6ZXV5,Q8TCS8,Q8NFC6,Q8WTT2,Q04446,O60934,Q15031,Q13148,O95394,P36578,P62910,P83881,P62899,Q9HAF1,P0CG13,P17096,Q9H488,P83731,P62269,P62750,P62841,Q7Z6E9,Q96ST3,Q9BY77,Q9H0A0,O60762,Q15056,P62277,Q96EY7,Q9NP81,O60832,P26373,P63173,Q9BY44,Q9P2E9,Q9Y2R9,Q9BZE4,P35251,P39023,P32969,P60866,P62917,Q96RP9,Q7LG56,Q99700,Q06265 121 +Regulation of telomere maintenance via telomere lengthening 0.3146755432974213 0.2425456179308311 0.8083574138377951 1.0 1.0 27 O60832,Q9H2U1,P09874,Q96BK5,Q15554,Q00839,Q9H0A0,Q01780,P35222,P17987 10 +Metencephalon development 0.3111027356858122 0.2420222767638436 0.8087629019105185 1.0 1.0 29 P18887,Q02218,Q06124,Q15058,Q9UKA9,P51608,Q9BRK5,O15020,P08069,O14949 10 +Regulation of dna templated transcription elongation 0.3128831171307922 0.2419101381393344 0.8088497943172328 1.0 1.0 28 Q86V81 1 +Regulation of endothelial cell migration 0.3128623743686744 0.2418467084480328 0.8088989448718276 1.0 1.0 28 Q9NWH9,Q16539,P31749,P46734,P78536 5 +Synaptonemal complex organization 0.3469202898550699 0.2400456381139637 0.8102948766156715 1.0 1.0 7 P46379,O60216,Q15645,P53350,Q96KQ7,P54652 6 +Glycerophospholipid biosynthetic process 0.2794187249207879 0.2398918755505381 0.8104140793580603 1.0 1.0 39 Q969N2,O60762,Q96S52,P17655,Q8WVX9,P48651,Q9UBF8,P78356,Q9HCL2,Q9NX62,Q9NTJ5 11 +Vesicle cargo loading 0.3075125793031654 0.2397728576811044 0.810506349676237 1.0 1.0 11 Q13492,P62820,Q5JRA6 3 +Skeletal muscle organ development 0.3162014173654218 0.2397487778949028 0.8105250181977555 1.0 1.0 25 Q9Y281,Q9BYT8,P80723,Q9BRT2,Q16539,Q9Y5Q8,P16989,P41440 8 +Positive regulation of neuron death 0.3179546382488347 0.2396551088143816 0.810597638772997 1.0 1.0 19 P17655,P42574,P09874,Q13492,Q07820,Q07812,P60953 7 +Microtubule bundle formation 0.3130374305535683 0.239452787388215 0.8107545018415754 1.0 1.0 14 O95235,Q9UHD1,Q99653 3 +Protein containing complex organization 0.2493697368947292 0.2391584137777618 0.8109827480261054 1.0 1.0 576 P55769,P62857,O15020,Q8N511,Q9NYY8,P11047,O95391,Q15428,Q8IUX1,Q7Z478,Q9NPF5,P07305,O14548,P35080,Q9NWH9,Q9BRT2,P03915,P14174,Q5TC12,Q99720,P54132,P62330,P34896,Q9BSK2,P16403,O75438,P82912,P62805,P10412,Q13247,O15160,Q8NE86,P60953,Q9ULR0,Q9NZM5,Q9H6R0,Q9HD47,Q9BSH4,Q86Y39,P53680,O75122,P62314,Q7Z7K6,Q9H7B2,P46100,O95139,Q9P0M6,Q8WWK9,O95400,Q8NFH5,Q00059,P50748,Q9NUL7,O75367,Q12824,O43676,Q02878,Q9Y3C0,Q9GZN1,Q9BT73,Q5SSJ5,O75340,Q8TCS8,O15144,O75616,P28331,Q92522,Q96CU9,Q9BTX1,Q9UHB6,O43809,Q9BZJ0,Q9Y281,O43819,O95168,P04179,P17096,P28289,Q16186,Q9P0J0,P83731,P09234,P16402,P62750,P62841,Q96T23,Q9H0U9 87 +Pigmentation 0.3171462507711517 0.2388165386433422 0.8112478452661465 1.0 1.0 18 P62820,P04179,O75787 3 +Regulation of cation transmembrane transport 0.2277625596203369 0.2386273456713171 0.8113945588201141 1.0 1.0 51 Q9HD47,Q99653,Q9UHD1,Q9BSH4,Q99996,Q09666,Q07812,P54709,P46939,P42858,P30405 11 +Response to mechanical stimulus 0.3173319011338112 0.2386142145500841 0.8114047418621213 1.0 1.0 23 Q16539,P61586,Q9Y624,P42858,P08069,P14923 6 +Response to misfolded protein 0.3193989873744169 0.2384292225849188 0.8115482045136875 1.0 1.0 9 Q9BUN8 1 +Developmental growth involved in morphogenesis 0.2432345671048498 0.237916843927029 0.8119455910134123 1.0 1.0 46 Q13740,P11047 2 +Medium chain fatty acyl coa metabolic process 0.6744045824540257 0.2378459858595314 0.8120005503562273 1.0 1.0 2 O00154 1 +Embryonic hemopoiesis 0.4048265460030185 0.2357563272384923 0.813621758753075 1.0 1.0 4 Q13043,Q13769,Q15648 3 +Glutamine family amino acid biosynthetic process 0.3452341729473478 0.2354128098039823 0.8138883446386758 1.0 1.0 7 P04181,P54886,Q96C36,P32322 4 +I kappab phosphorylation 0.357005877745609 0.2342597031260719 0.8147833678025473 1.0 1.0 6 P31749 1 +Mrna 5 splice site recognition 0.3722843774283812 0.2339302610213683 0.8150391200122173 1.0 1.0 5 O75475,P09234 2 +Positive regulation of muscle cell differentiation 0.3443884976770428 0.2331086914263082 0.8156770060216751 1.0 1.0 7 Q16539 1 +Regulation of lipid transport 0.3155649832863067 0.2321480168360108 0.8164230513583062 1.0 1.0 20 P31749,P82094 2 +Peptidyl proline modification 0.2954395628602105 0.232130007372234 0.8164370388261117 1.0 1.0 34 Q13162,P26885,Q96BP3,P30405,Q9Y237,Q9H2H8,P45877 7 +Defense response to gram negative bacterium 0.4030359580233588 0.2313894130576901 0.8170122891751737 1.0 1.0 4 P39019 1 +Respiratory chain complex iv assembly 0.3436176607052118 0.2310198640140047 0.817299370147921 1.0 1.0 7 Q9BSH4 1 +Focal adhesion assembly 0.3147437948847975 0.2298791946746293 0.8181856436642381 1.0 1.0 20 Q9HCM4,Q9Y2S7 2 +Regulation of nitric oxide metabolic process 0.3033769980572232 0.2285338633351027 0.819231233425681 1.0 1.0 11 P31749 1 +Regulation of dephosphorylation 0.2840758459589065 0.2284404739530086 0.8193038274864279 1.0 1.0 37 Q86XL3,Q99653,Q12972,P42858,Q5H9R7,Q15435 6 +Negative regulation of epithelial cell apoptotic process 0.3156398570323629 0.2282289245531801 0.8194682762112306 1.0 1.0 9 Q13247,P08069,O15446 3 +Histone h4 k16 acetylation 0.3030918666913416 0.2277744811259009 0.8198215663649042 1.0 1.0 11 Q12824 1 +Cellular glucan metabolic process 0.3112121726788595 0.2272710362808724 0.8202129935456552 1.0 1.0 16 P31749,P62140 2 +Aging 0.2468566434650533 0.2271731663433924 0.8202890923942008 1.0 1.0 65 P46100,P04844,Q8TCS8,P42771,Q16539,P04179,Q15554,P14174,P17096,Q96ST3,Q9NX47,O43324,Q96SB8,P46734 14 +Cellular response to osmotic stress 0.3048216581698327 0.2267627375348246 0.820608240061574 1.0 1.0 12 P42574,O95202,P16989 3 +Dna damage response signal transduction by p53 class mediator 0.3130054981687274 0.2251387249263658 0.8218713560592692 1.0 1.0 20 P46100,P14174,O43324 3 +Cellular response to estrogen stimulus 0.4003560883472246 0.2249388280145811 0.8220268628207559 1.0 1.0 4 Q969T9 1 +Regulation of response to cytokine stimulus 0.3053113114035682 0.2246922975199287 0.8222186570975789 1.0 1.0 29 Q8TCT8,Q9Y5A9,Q86Y07 3 +Immune response regulating signaling pathway 0.2370052790572306 0.2246631619723055 0.8222413244938105 1.0 1.0 59 Q9UI10,Q9NZM5,P41440,Q3LXA3 4 +Cytoplasmic sequestering of nf kappab 0.3998092211587832 0.2236350958238323 0.8230412526990942 1.0 1.0 4 O60826 1 +Positive regulation of leukocyte proliferation 0.3067466775735538 0.2224724366768077 0.8239461279874407 1.0 1.0 14 P14174 1 +Cellular process involved in reproduction in multicellular organism 0.2224150492912749 0.2223421483238801 0.8240475435177554 1.0 1.0 50 A0AVF1,P11388,Q13162,Q9H6S0,P09622,P05556,Q9Y5A9,Q07812,P82094,P31749,P62753,Q8NHU6,P20042,Q6IBW4,Q01085,Q92879,O94813 17 +Calcium mediated signaling 0.3118557364705909 0.2222025182060888 0.8241562338730082 1.0 1.0 22 Q99653,P42858 2 +Positive regulation of interleukin 2 production 0.3519468759432564 0.22068658926806 0.8253364742447276 1.0 1.0 6 P23396,P00491,Q01082,Q92990,Q9UJZ1 5 +Cardiac muscle cell membrane repolarization 0.3394660525489536 0.2199578131009166 0.8259040103301825 1.0 1.0 7 Q99996 1 +Cytoplasmic sequestering of transcription factor 0.3668322376923179 0.2199145581088026 0.8259376981160915 1.0 1.0 5 O60826 1 +Rna processing 0.387556984763434 0.2196258786539466 0.8261625352047186 1.0 1.0 507 Q96T37,P22087,Q86V81,P55769,Q969Y2,Q2NL82,Q68CQ4,P62857,Q9BYD6,Q9NVH2,Q9Y3A5,Q86W42,Q9NYY8,Q07021,O95391,Q15428,P08621,Q8TCT8,Q9Y5A9,O94906,P46087,P52272,P62081,Q8TDN6,Q96B26,Q92879,Q9BWJ5,Q13868,Q9NR30,Q96BP3,Q9Y4C8,Q9UNP9,Q9NWH9,Q99848,O15213,P62847,Q99547,P62312,P08579,O75127,Q99575,Q15427,Q96DE0,Q8TBF4,Q9BUQ8,Q9NW13,Q9NXG2,Q9NW64,Q14137,Q9BSC4,O00541,P18077,P24928,P50914,Q9NX58,Q9H501,P39019,Q8WXA9,P82912,P31483,Q13247,Q7L8L6,Q8IYB8,Q9NQ55,Q9Y4W2,Q8TDD1,Q12972,Q5T8P6,O43709,Q9ULR0,P57678,Q9NZM5,P61353,Q13206,P62318,P62314,Q8IY67,Q9H974,Q9H7B2,Q9GZR2,Q9Y2L1,Q6P2Q9,Q96DI7,Q96GQ7,Q5JTZ9,O75475,Q9Y3A2,Q969Z0,O95400,Q8IWZ8,Q6P6C2,Q8IY81,Q9Y237,Q8NEF9,Q8IXT5,Q9H2U1,P62424,Q9BVJ6,Q9ULW3,Q9NY93,Q9UKA9,Q15233,Q8TEA1,Q9UMS4,Q9UNY4,Q5VV42,Q86U42,Q15046,P09012,O00567,O60306,P08708,Q8TCS8,Q9ULX6,Q13610,Q8N201,Q13601,P62854,P62753,Q96CB8,Q9BTD8,Q15424,Q9NPF4,Q8IX01,Q9NXH9,Q7L014,Q9Y6V7,Q9Y3I0,Q8N5L8,Q13148,Q9BV44,O43809,O95478,Q9BZJ0,Q9BZL1,Q9H2H8,Q9UJA5,Q9Y3C6,Q6DKI1,Q5RKV6,Q8NI27,Q9H583,Q5VTL8,P09234,P62841,Q09666,Q7Z6E9,Q9H0A0,Q9NVP1,P62277,Q13595,Q99590,Q9BUJ2,P33240,O60832,O76021,Q12788,Q14151,Q14684,Q92620,Q9BYG3,Q9H0S4,Q9P2N5,Q9UNQ2,Q9Y2P8,Q9BZE4,Q9H9Y2,Q9Y312,Q13895,Q15637,Q06265 171 +Regulation of lamellipodium assembly 0.3056511794869355 0.2196185996942926 0.8261682045839611 1.0 1.0 14 P47756,P61160,O15144,P60953,O94813 5 +Caveolin mediated endocytosis 0.4445114595898617 0.2192381569822694 0.8264645334410345 1.0 1.0 3 P28482,Q9UNF0 2 +Regulation of b cell apoptotic process 0.397906992304336 0.2191336354787509 0.8265459501273753 1.0 1.0 4 P14174 1 +Renal filtration 0.6641543563460894 0.2188746724966447 0.826747676534711 1.0 1.0 2 Q9NQH7 1 +Eosinophil activation 0.6638528791076203 0.2183311518430489 0.8271711042121155 1.0 1.0 2 P51809 1 +Eosinophil mediated immunity 0.6638528791076203 0.2183311518430489 0.8271711042121155 1.0 1.0 2 P51809 1 +Regulation of dna biosynthetic process 0.2436769765972536 0.2173829747677771 0.827909898143937 1.0 1.0 45 Q96BK5,P0CG13,Q15554,Q9H0A0,Q9HAF1 5 +Regulation of presynaptic cytosolic calcium ion concentration 0.6632499246306873 0.2172466024970078 0.8280161682708038 1.0 1.0 2 P20020 1 +Formation of primary germ layer 0.3043053609556075 0.2161547365850753 0.8288671344347343 1.0 1.0 14 Q9HCM4,O75367,P05556,Q96A65,Q92541,P35222 6 +Regulation of membrane permeability 0.3092362359002006 0.2159929863655653 0.8289932146054309 1.0 1.0 19 P30405,Q9Y624,P05141,Q9UII2 4 +Thioester metabolic process 0.2837106893559826 0.2159366925619938 0.8290370952230055 1.0 1.0 36 P36957,P10515,Q02218,Q4G176,Q15120,Q8WVX9,Q9P2R7,O95563,P08559,Q9HCL2,Q96I99,Q92947,Q03426 13 +Regulation of actin filament length 0.2317111891751702 0.2157953962234306 0.8291472370585058 1.0 1.0 47 Q9UHB6,Q9Y281,P35080,P62330,O15144,O15020 6 +Chondrocyte differentiation 0.3104698418521344 0.2147118640551693 0.829991972125327 1.0 1.0 9 Q9NX62,P50454,Q16539 3 +Protein autophosphorylation 0.2676303021758789 0.214557216567019 0.8301125532680977 1.0 1.0 40 Q99653,P31749,Q99986,Q86Y07 4 +Sperm capacitation 0.661742538438342 0.214549780820422 0.8301183511405801 1.0 1.0 2 P09622 1 +Regulation of stem cell differentiation 0.3086715409106878 0.2145324903477501 0.8301318330714538 1.0 1.0 19 Q13610,Q9Y5A9 2 +Cellular amide metabolic process 0.2443156620879672 0.2136979631778725 0.8307825998034082 1.0 1.0 486 Q7Z7F7,Q5T653,P61513,P82914,Q16775,Q9UI10,Q8N3C0,P62857,Q9UGM6,P41440,Q9NYY8,Q07021,Q9Y5A9,P46776,P62081,Q96B26,Q7Z478,Q92879,Q9BUT1,Q9BW92,Q9BYT8,Q13868,Q13492,Q9BRT2,P31749,O15217,P62847,P82675,Q8N983,P36957,Q5ST30,Q96RQ3,P47914,P34896,Q9HCL2,Q9UKZ1,Q9NQW7,Q9NX20,Q9P2R7,P62244,P04406,P18077,Q9Y3U8,P50914,P62701,P62280,P61586,Q9Y3D3,P39019,Q96I99,P82912,Q8TB36,P31483,Q99797,Q9NRA0,Q9P0L0,Q9Y285,Q9H6R0,Q8WU90,Q5T160,O75175,Q9BSH4,P61353,P16989,O43324,Q9Y2Q3,P84098,P61313,Q02878,P62424,Q8NFW8,Q9UHA3,Q5VV42,Q567V2,O75787,Q8TCS8,O95563,P08559,Q15031,Q13148,Q04760,P36578,P62910,P83881,P62899,P04179,Q8WVX9,P83731,P42574,P62269,P62750,P62841,Q9BY77,Q9H0A0,P10515,Q15056,P62277,Q02218,Q96EY7,Q9NP81,Q92947,P26373,P63173,Q4G176,Q15120,Q9BY44,Q9P2E9,Q9Y2R9,Q03426,P39023,P32969,P60866,P62917,Q96RP9,Q99700,Q06265 116 +Cellular response to hydrogen peroxide 0.3085147710452718 0.2132839812546665 0.8311054672161393 1.0 1.0 20 Q99720,Q9NWH9 2 +Chaperone cofactor dependent protein refolding 0.3057755624601512 0.2130920815841815 0.8312551407922284 1.0 1.0 16 P17066,P25685,P61604,Q9HCN8,Q96HE7 5 +Transcytosis 0.3098231412832111 0.2130630667383063 0.8312777716699975 1.0 1.0 9 P20339,Q13492,P08069 3 +Negative regulation of endothelial cell proliferation 0.363882846991448 0.2125335975048875 0.8316907694135987 1.0 1.0 5 Q9UII2 1 +Regulation of mononuclear cell migration 0.3071198605414038 0.2119784243737694 0.8321238666819772 1.0 1.0 18 Q07021,Q5JRA6,Q08722,P31749,P61586,O94813,P78536 7 +Synaptic vesicle recycling 0.3062455641728632 0.2117404050078213 0.8323095640842078 1.0 1.0 17 P62330 1 +Neurotransmitter transport 0.3051395469987683 0.2116988580021489 0.8323419790913564 1.0 1.0 26 P41440,P35080 2 +C21 steroid hormone metabolic process 0.4410079062715034 0.2116720877451561 0.8323628654183726 1.0 1.0 3 P30536 1 +Regulation of mitochondrial membrane permeability 0.3038114442605178 0.2112321530675271 0.8327061222324155 1.0 1.0 15 P30405,P05141,Q07812,Q9UII2 4 +Blastocyst formation 0.3037434554217895 0.2110614776610697 0.8328392994497105 1.0 1.0 15 O75175,O95140,Q6DKI1 3 +Termination of rna polymerase ii transcription 0.6593307205305962 0.2102781872161686 0.8334505587767034 1.0 1.0 2 Q9UNY4 1 +Membrane depolarization 0.2939265654978855 0.2101813405629838 0.8335261423672027 1.0 1.0 10 Q9UII2,Q9HD47 2 +Positive regulation of mrna processing 0.3069769473192734 0.2093544501572845 0.8341715483187646 1.0 1.0 20 Q9H2U1,O43809,P08621,Q13595,Q15427 5 +Osteoclast differentiation 0.3082904486294883 0.2091928780598312 0.834297671918949 1.0 1.0 9 Q16539 1 +Protein folding in endoplasmic reticulum 0.3074118428181345 0.2069981419268579 0.8360113096023274 1.0 1.0 9 Q9P0L0,P27797,P30101,Q96HE7,Q8IXB1 5 +Positive regulation of rna splicing 0.3056800367168938 0.2069140213498065 0.8360770060232459 1.0 1.0 23 Q9NW64,P08621,P24928,Q13595,Q15427 5 +Meiotic chromosome segregation 0.3053670436869241 0.2061181744732611 0.8366986024023613 1.0 1.0 23 P61160,Q02880,O60216,O95347,Q9BTX1,O94901 6 +Anterograde axonal transport 0.3039915483463794 0.2061061599580248 0.8367079871244418 1.0 1.0 17 Q9NVJ2,O60333,Q15554 3 +Positive regulation of transmembrane transport 0.2766928368119953 0.2055407375242108 0.837149673516854 1.0 1.0 37 Q99653,Q9UHD1,Q99996,Q16539,P31749,P54709,P42858 7 +Regulation of chromatin assembly or disassembly 0.2999816377972384 0.2053409579576766 0.8373057459580628 1.0 1.0 14 Q66K74,O75367,Q96ST3 3 +Myeloid leukocyte mediated immunity 0.3050124343875403 0.2052819781661685 0.8373518235665633 1.0 1.0 19 O75083,Q9NR30,Q9H2U1,Q9NRA0,Q9NY93,Q99584,P51809,Q8N5M9,P78536 9 +Embryonic pattern specification 0.3336748981311322 0.2050633297672188 0.8375226461837779 1.0 1.0 7 Q9HCM4,P80723 2 +Embryonic axis specification 0.3336748981311322 0.2050633297672188 0.8375226461837779 1.0 1.0 7 Q9HCM4,P80723 2 +Phosphatidylinositol phosphate biosynthetic process 0.2939496744622313 0.2044945274398618 0.8379670681119267 1.0 1.0 11 Q9NX62,P78356,Q9UBF8 3 +Mitochondrial fission 0.2995082505598296 0.2041861891209822 0.8382080034933348 1.0 1.0 14 Q9NX47 1 +Regulation of calcium ion dependent exocytosis 0.3604351670955544 0.2040868274172768 0.8382856479031393 1.0 1.0 5 Q00535,O00186,P16615 3 +Protein complex oligomerization 0.2375346401199345 0.2035491902254982 0.8387058020723208 1.0 1.0 63 Q99720,Q8TCS8,Q99797,P54132,O43809,O43633,P34896,P04179,Q9UN86,Q9Y285,Q8NE86,Q9H8V3,Q96CX2,P14174,Q9UJZ1 15 +Dna packaging 0.2670251513112415 0.2035038904591098 0.8387412051584966 1.0 1.0 83 P10412,O75367,P46100,P16403,P16402,Q9P0M6,Q9ULX6,Q96ST3,Q96T23,Q5SSJ5,Q7Z7K6,Q92522,P62805,P07305 14 +Endothelial cell migration 0.2794737626924419 0.203434855351853 0.8387951587321891 1.0 1.0 36 Q9NWH9,Q16539,P31749,P51153,P46734,P78536 6 +Intrinsic apoptotic signaling pathway in response to dna damage 0.302837361572551 0.2030854504333019 0.8390682436421537 1.0 1.0 25 Q9BVC6,P14174,Q07820 3 +In utero embryonic development 0.2906554729733079 0.2022882402605929 0.8396913928519107 1.0 1.0 100 Q9HCM4,Q16706,Q13503,P17655,O75175,Q9Y6I3,O95140,Q12824,Q6DKI1,O43819,Q15554,Q7Z6E9,P31749,P16989,Q9BZK7,Q9Y3Y2,O60568,O60934 18 +Positive regulation of cell growth 0.2546592715205911 0.2022592389343566 0.8397140639947607 1.0 1.0 42 O43909,Q13868,P31749,P60953,Q9BSK2 5 +Negative regulation of mrna metabolic process 0.2279450097400205 0.2019293840775073 0.8399719300585726 1.0 1.0 47 Q13247,P16989,Q9BTD8,Q16539 4 +Negative regulation of helicase activity 0.3900452488687803 0.2010862134404004 0.840631161897301 1.0 1.0 4 P49736,Q96EB6,P33993 3 +Regulation of microtubule polymerization 0.3032962130452457 0.2001379081318545 0.8413727266747402 1.0 1.0 22 Q9NWH9,Q99996,Q9HD47 3 +Formation of translation preinitiation complex 0.3180626234465523 0.1988521927680828 0.8423783672335354 1.0 1.0 8 Q7Z478 1 +Protein localization to plasma membrane 0.2697775853962196 0.1986260156328049 0.8425553015386669 1.0 1.0 86 Q92930,Q9HD47,P62330,Q9BXS4,P35613,P31749,Q9UJY5,Q9Y624,P51153,Q5VZ89,P41440 11 +Cytoplasmic pattern recognition receptor signaling pathway 0.3016029236371308 0.1983730949166274 0.8427531662800429 1.0 1.0 18 Q9NZM5,Q9NUD5,Q9H078,Q3LXA3 4 +Apoptotic mitochondrial changes 0.2838158640145399 0.1980135742865814 0.8430344432674501 1.0 1.0 34 P05141,Q96A26,P04179,P31749,P28331,P30405,Q9UII2 7 +Telomere capping 0.2948142051078873 0.1969654348659382 0.8438545868635765 1.0 1.0 13 Q15554 1 +Nadh oxidation 0.6511908350919478 0.1962569725841665 0.8444090373260504 1.0 1.0 2 P43304 1 +Odontogenesis 0.2903621048637768 0.195927961052117 0.8446665516427059 1.0 1.0 11 P61586,Q07812,Q92769,P35613 4 +Synaptic vesicle exocytosis 0.299491389669978 0.195263875469584 0.8451863758952596 1.0 1.0 17 P35080 1 +Establishment or maintenance of cell polarity 0.2465700250783306 0.1939242896908743 0.8462351642948307 1.0 1.0 71 Q92614,Q9Y5S2,P62330,P60953,P42858 5 +Dna topological change 0.3412678942337842 0.1934768563695626 0.8465855295537714 1.0 1.0 6 Q02880,P11388 2 +Er associated misfolded protein catabolic process 0.3287214094878596 0.192826221314963 0.8470950672134487 1.0 1.0 7 Q9BUN8 1 +Histone h4 k20 methylation 0.3555198267702582 0.1923857042251525 0.8474400896167877 1.0 1.0 5 Q96L73 1 +Positive regulation of cellular biosynthetic process 0.2010867033877111 0.1923060563772306 0.847502474637575 1.0 1.0 410 Q96T37,Q13503,Q12824,O60244,Q86V81,O14641,Q9NY93,Q96L73,Q96ST3,Q9NX58,Q96T23,Q6PL18,Q9ULV3,Q9BY77,Q567V2,P41440,P46734,Q9NYY8,Q99653,Q9ULX6,Q13610,Q9Y5A9,Q5VUA4,Q9H2V7,P60953,Q7Z478,Q9H6R0,P17655,Q92604,Q9NWH9,Q9BRT2,Q16539,P13984,P82094,P31749,P05114,P16989,P46100,P54132,P0CG13,P04179,Q8WWK9,P17096,Q969T9,Q9BZK7,Q00059,Q49A26,Q9H583,Q9Y613 49 +Peptide metabolic process 0.2736258927165165 0.1920251910702247 0.8477224729885238 1.0 1.0 409 Q7Z7F7,Q5T653,P61513,P82914,Q16775,Q9UI10,Q8N3C0,P62857,Q9UGM6,Q9NYY8,Q07021,Q9Y5A9,P46776,P62081,Q96B26,Q7Z478,Q92879,Q9BUT1,Q9BW92,Q9BYT8,Q13868,Q13492,Q9BRT2,P31749,O15217,P62847,P82675,Q8N983,Q5ST30,P47914,P34896,Q9UKZ1,Q9NQW7,Q9NX20,P62244,P04406,P18077,Q9Y3U8,P50914,P62701,P62280,P61586,Q9Y3D3,P39019,P82912,P31483,Q9H6R0,Q8WU90,Q5T160,O75175,Q9BSH4,P61353,P16989,O43324,Q9Y2Q3,P84098,P61313,Q02878,P62424,Q9UHA3,Q5VV42,Q567V2,O75787,Q8TCS8,Q15031,Q13148,Q04760,P36578,P62910,P83881,P62899,P04179,P83731,P42574,P62269,P62750,P62841,Q9BY77,Q9H0A0,Q15056,P62277,Q96EY7,Q9NP81,P26373,P63173,Q9BY44,Q9P2E9,Q9Y2R9,P39023,P32969,P60866,P62917,Q96RP9,Q99700,Q06265 95 +Germ cell development 0.2678888366788211 0.1910399801423754 0.848494270327218 1.0 1.0 38 Q9Y5A9,P82094 2 +Negative regulation of glial cell proliferation 0.4309624188640197 0.1908551549128117 0.8486390754463884 1.0 1.0 3 P30536 1 +Actin filament based movement 0.2955017761428401 0.1903561416692538 0.8490300631130301 1.0 1.0 27 Q9HCM4,O00159,Q9HD47,Q99996,O43795,Q14126,Q9UH99 7 +Nucleus organization 0.2497926471540709 0.1903057485968863 0.8490695492412341 1.0 1.0 74 O75367,Q86XL3,Q9H9Y6,Q9ULX6,P82094,Q8NFH5,Q6NUK4,Q5JTV8,Q9H6H4,Q9BPY3,Q9BTX1,O94901,Q99986 13 +10 formyltetrahydrofolate metabolic process 0.4304856060088248 0.18989969029053 0.8493877351656074 1.0 1.0 3 Q6UB35 1 +Amide biosynthetic process 0.2872835868689586 0.1894980820941202 0.8497024581334565 1.0 1.0 400 Q7Z7F7,Q5T653,P61513,P82914,Q16775,Q9UI10,Q8N3C0,P62857,Q9UGM6,Q9NYY8,Q07021,Q9Y5A9,P46776,P62081,Q96B26,Q7Z478,Q92879,Q9BUT1,Q9BW92,Q13868,Q9BRT2,P31749,P62847,P82675,Q8N983,Q5ST30,P47914,P34896,Q9UKZ1,Q9NX20,P62244,P04406,P18077,Q9Y3U8,P50914,P62701,P62280,P61586,Q9Y3D3,P39019,P82912,P31483,Q9NRA0,Q9P0L0,Q9Y285,Q9Y6M1,Q9H6R0,Q8WU90,Q5T160,O75175,P52758,P09622,Q9BSH4,P61247,P61353,P16989,O43324,Q9Y2L1,P84098,Q5JTZ9,P62487,P61313,Q12906,Q53H12,Q7L2H7,Q02878,P62424,Q9H2U1,Q9UMR5,Q9UHA3,Q5VV42,Q567V2,Q15046,P08708,Q8TCS8,P30050,Q13347,O95563,P82979,P62854,P62753,P08559,P62266,Q15031,Q13148,P36578,P62910,P83881,P62899,P83731,P62269,P62750,P62841,Q9BY77,Q9H0A0,P10515,Q15056,P62277,Q96EY7,Q9NP81,Q92947,P26373,P63173,Q4G176,Q15120,Q9BY44,Q9P2E9,Q9Y2R9,P39023,P32969,P60866,P62917,Q96RP9,Q99700,Q06265 115 +Regulation of secretion 0.2883149754957542 0.1880716920277946 0.850820451590339 1.0 1.0 102 Q92930,P55809,P35080,Q92614,P62330,Q9BRT2,P82094,P20339,Q8NE86,P51153,Q8N5M9,P14174 12 +Osteoblast proliferation 0.3837894642828665 0.1873747959823683 0.8513667825107933 1.0 1.0 4 P61586 1 +Regulation of osteoblast proliferation 0.3837894642828665 0.1873747959823683 0.8513667825107933 1.0 1.0 4 P61586 1 +Nuclear pore organization 0.2878721522950975 0.1854125528997234 0.8529054633329891 1.0 1.0 12 Q8NFH5,Q9BTX1 2 +Cellular response to insulin stimulus 0.2182305405918661 0.1841009296558779 0.8539342771853349 1.0 1.0 54 Q92930,O00159,P20020,O14654,P09874,Q06124,P61006,Q9BSK2,P31749,P78356,P51153,Q5VZ89,P08069,Q9UKG1 14 +Actin filament polymerization 0.2225848582958128 0.183996110043124 0.8540165065618757 1.0 1.0 47 P35080,Q9Y3C0,P62330,O15144,O15020 5 +Dna templated transcription elongation 0.2436340968059543 0.1835280215007852 0.8543837341772478 1.0 1.0 43 P05114,Q86V81,P13984,O15160 4 +Import into nucleus 0.2401993546825979 0.1833116131786679 0.8545535227942769 1.0 1.0 69 Q9NW64,Q9HD47,Q99653,Q16539,P31749,Q96QC0,Q9NPF5 7 +Lamellipodium organization 0.2924042381098631 0.1830465110872786 0.8547615245170948 1.0 1.0 27 P60953,P53365 2 +Protein heterotetramerization 0.3245697973816068 0.1829317657817798 0.8548515579494396 1.0 1.0 7 O43809 1 +Mrna metabolic process 0.2789135529937318 0.1813633167859553 0.856082410321964 1.0 1.0 371 Q9NW64,Q5VTL8,Q96T37,P09234,Q9BRJ7,Q86V81,P55769,Q7Z6E9,P09012,Q86W42,P31483,Q9NYY8,Q13247,Q7L8L6,Q8TCS8,O95391,Q15428,Q9ULX6,Q13595,Q9Y5A9,Q99590,Q12972,Q9ULR0,Q9BWJ5,Q9BTD8,P33240,O60832,O75175,Q13868,Q13148,Q96BP3,Q9Y4C8,O43809,Q9NWH9,Q14151,Q16539,Q14684,Q92620,Q9H0S4,P31749,P16989,P62314,P62312,Q9BZJ0,Q9BZL1,Q9H2H8,Q9UJA5,Q9Y3C6,Q96DI7,Q5RKV6,Q8TBF4,Q969Z0,O95400,Q8IWZ8,Q6P6C2,Q9UKZ1,Q8NI27 57 +Regulation of protein depolymerization 0.2743163474125296 0.1811400324464746 0.8562576629610468 1.0 1.0 35 Q9UHB6,Q9Y281,Q8WWK9,O75122,O15020 5 +Chromosome organization 0.1754690019819254 0.1810830245595037 0.8563024087608209 1.0 1.0 370 Q96T37,O75367,Q12824,P16403,Q53HL2,P16402,Q15554,Q9GZN1,Q96L73,Q96ST3,Q96T23,Q6PL18,Q5SSJ5,Q9H0A0,P62805,P41440,O94901,P10412,Q9ULX6,Q9H2V7,O60934,P46013,O43709,Q92522,Q9NPF5,Q96SB8,P07305,Q9BTX1,Q2NKX8,P13984,P05114,Q7Z7K6,Q9HAF1,P46100,P54132,Q96BK5,Q9P0M6,P0CG13,P17096,Q969T9,Q96QC0,Q9BZK7,P50748,Q9Y6D9 44 +Regulation of neurotransmitter levels 0.2907479125629955 0.1792643713341591 0.8577301212055322 1.0 1.0 27 P41440,P35080 2 +Histone h2a monoubiquitination 0.37978883861237 0.1789119681916272 0.8580068251570621 1.0 1.0 4 P63208,Q13620,Q16531 3 +Mitochondrial membrane organization 0.2090128618740371 0.1787061925013149 0.8581684065498127 1.0 1.0 49 Q9NS69,O95140,O60220,Q5HYI7,P30405,Q9P0J0 6 +Energy derivation by oxidation of organic compounds 0.3155889589499034 0.1786133910010094 0.8582412790829257 1.0 1.0 126 P56134,O75438,P50213,O43676,P48047,P38117,P61586,Q96I99,Q99798,P30405,Q9UJZ1,Q9UDW1,P10515,P19404,Q8TCS8,Q02218,Q04446,P08559,P28331,Q9NZM5,P14927,O14548,P20674,Q9BRT2,O75380,P31749,P08574,P03915,P36957,P62140,O95139,O43819,Q9BSK2,O95168,P04179,Q9P2R7,Q16795,O14949 38 +Peptide biosynthetic process 0.3086455340937216 0.1785610443461547 0.8582823849139594 1.0 1.0 361 Q7Z7F7,Q5T653,P61513,P82914,Q16775,Q9UI10,Q8N3C0,P62857,Q9UGM6,Q9NYY8,Q07021,Q9Y5A9,P46776,P62081,Q96B26,Q7Z478,Q92879,Q9BUT1,Q9BW92,Q13868,Q9BRT2,P31749,P62847,P82675,Q8N983,Q5ST30,P47914,P34896,Q9UKZ1,Q9NX20,P62244,P04406,P18077,Q9Y3U8,P50914,P62701,P62280,P61586,Q9Y3D3,P82912,P31483,Q9H6R0,Q8WU90,Q5T160,O75175,Q9BSH4,P61353,P16989,O43324,P84098,P61313,Q02878,P62424,Q9UHA3,Q5VV42,Q567V2,Q8TCS8,Q15031,Q13148,P36578,P62910,P83881,P62899,P83731,P62269,P62750,P62841,Q9BY77,Q9H0A0,Q15056,P62277,Q96EY7,Q9NP81,P26373,P63173,Q9BY44,Q9P2E9,Q9Y2R9,P39023,P32969,P60866,P62917,Q96RP9,Q99700,Q06265 85 +Embryonic neurocranium morphogenesis 0.6403376545070764 0.1785169314071246 0.858317025420398 1.0 1.0 2 Q6UB35 1 +Genomic imprinting 0.4246079613992756 0.1783667802901738 0.85843493642384 1.0 1.0 3 P49711,Q6PD62 2 +Response to oxygen levels 0.2310788601744658 0.1779515717202145 0.858761008766451 1.0 1.0 64 P17655,P42574,Q96A26,P04179,P31749,Q6P6C2,Q5SSJ5,Q9NZM5,P03915,Q8N511,P78536 11 +Positive regulation of neuron apoptotic process 0.2844356272631004 0.1779111081255271 0.8587927869988512 1.0 1.0 12 P42574,Q07820,P60953,Q07812 4 +Response to insulin 0.2292936689866436 0.177014844066858 0.859496729824216 1.0 1.0 63 Q92930,Q13247,Q9BSK2,P31749,P51153,Q5VZ89 6 +Dna modification 0.2849512345139337 0.1769422611493082 0.8595537427232907 1.0 1.0 30 P46100,Q5RKV6,P51608,Q8N3C0,Q9NPF5 5 +Regulation of epithelial cell apoptotic process 0.2816371980808753 0.1764369153530794 0.8599507052843884 1.0 1.0 11 Q13247,P08069,O15446 3 +Cellular response to heat 0.2894030320313923 0.1762578931875661 0.8600913404515869 1.0 1.0 27 O75340,O95391,Q9UHD1,P17066,P25685,Q9H078 6 +Regulation of dendritic cell chemotaxis 0.6388302683147301 0.1761397150100676 0.8601841805927499 1.0 1.0 2 Q07021 1 +Protein localization to cilium 0.2907835778871711 0.1758190885906171 0.8604360727154483 1.0 1.0 17 Q9Y5K8,P61006,Q9UJY5 3 +Cellular response to reactive oxygen species 0.2776955129671981 0.175759930970702 0.8604825499715596 1.0 1.0 33 P31749,Q9NWH9,P30405,Q99720 4 +Striated muscle cell development 0.284946166355435 0.1749759152762782 0.8610985584374999 1.0 1.0 13 P28289,Q9Y281 2 +Peptide antigen assembly with mhc protein complex 0.6379258365993326 0.1747235498982979 0.8612968622736084 1.0 1.0 2 P27797 1 +Regulation of histone modification 0.23351468820858 0.1725096425234507 0.8630368813652007 1.0 1.0 67 O75367,Q12824,P46100,Q969T9,Q96L73,Q9Y3Y2,Q49A26 7 +Regulation of transport 0.1857291751145761 0.1721210603779781 0.8633423560594173 1.0 1.0 338 Q9NW64,Q92614,Q9UMY4,Q9NX58,Q8N5M9,P41440,Q99653,Q8NE86,P60953,P42858,P51153,Q9NPF5,P55809,P35080,Q9HD47,Q9BSH4,Q9BRT2,Q16539,P82094,P53680,P31749,P20339,P14174,Q92930,P62330,Q07960,Q9BVC6 27 +Negative regulation of chromosome organization 0.2441150367254151 0.1720645751576964 0.863386762285836 1.0 1.0 42 P46100,Q96BK5,Q15554,O60934,P50748,Q9Y6D9 6 +Protein processing 0.212811132485278 0.1719176497780387 0.8635022706577706 1.0 1.0 48 P17655,O15446,Q99797,P42574,Q9UMY4,P09874,Q9BXS4,Q8NEB9,Q9UJZ1,P78536,O75787 11 +Ncrna metabolic process 0.4500231078180766 0.1718934468431485 0.8635212985666696 1.0 1.0 286 P22087,P55769,Q969Y2,Q2NL82,Q68CQ4,Q8NHU6,P62857,Q9BYD6,Q9NVH2,Q9UGM6,Q9Y3A5,O15446,Q8TCT8,Q9Y5A9,P46087,P62081,Q8TDN6,Q96B26,Q9BW92,Q13868,Q9NR30,Q99848,O15213,P62847,Q99547,P62312,O75127,Q99575,Q5ST30,Q96DE0,Q9Y5Q8,Q9NXG2,Q14137,Q9BSC4,O00541,Q9BRJ7,P18077,P50914,Q9NX58,Q9H501,P39019,Q8WUA4,P82912,O15160,Q9GZS1,Q9NQ55,Q9Y4W2,Q9H2V7,Q9Y285,Q8TDD1,O43709,Q9NZM5,Q5T160,P61353,Q9H9Y6,Q9H974,Q9H7B2,Q9GZR2,P46100,Q9P0M6,Q96GQ7,Q9Y3A2,Q8IY81,Q9Y237,O75367,Q12824,P62424,Q9NY93,Q8TEA1,Q5VV42,Q8TCS8,Q13610,Q8N201,Q9NPF4,Q9NXH9,Q9Y6V7,Q15031,Q8N5L8,O95478,Q9UJA5,Q6DKI1,Q5RKV6,Q9H583,P62841,Q12789,Q9H0A0,Q9NVP1,Q9NP81,O60832,O76021,P62875,Q12788,Q14684,Q9BYG3,Q9H0S4,Q9UNQ2,Q9Y2P8,Q9Y5Q9,Q9BZE4,Q9H9Y2,Q13895,Q06265 102 +Maintenance of protein location in cell 0.2904669800535923 0.1715850903125328 0.8637637298095762 1.0 1.0 23 P31749,Q9ULV3 2 +Ribonucleoprotein complex biogenesis 0.4502478114458456 0.1715125311440163 0.8638207780079707 1.0 1.0 289 P22087,P55769,Q2NL82,Q68CQ4,P62857,Q9BYD6,Q9Y3A5,Q9NYY8,Q07021,Q9NVU7,O95391,Q15428,Q8TCT8,O94906,Q9Y5A9,P46087,P62081,Q8TDN6,Q96B26,Q92879,Q7Z478,Q13868,Q9NR30,Q99848,O15213,P62847,Q99547,P62312,Q96BK5,Q96DE0,Q9BUQ8,Q14137,Q9BSC4,O00541,P18077,P50914,Q9NX58,Q9H501,P39019,P82912,Q13247,Q9NQ55,Q9Y4W2,Q8TDD1,O43709,P57678,Q9ULR0,Q9NZM5,P61353,Q13206,P62318,P62314,Q9H7B2,Q9GZR2,Q9Y2L1,Q6P2Q9,Q96GQ7,O75475,Q9Y3A2,O95400,O75683,Q8IY81,Q9Y237,Q9BQG0,Q9NUL7,Q8NEF9,Q02878,Q9BVJ6,Q9ULW3,P62424,Q9NY93,Q9UKA9,Q9UMS4,Q9UHA3,Q567V2,O00567,P08708,Q13610,Q13601,O75616,Q9Y6V7,O43809,O95478,Q9BZJ0,Q6DKI1,Q5RKV6,Q969S3,Q9H9L3,Q9H583,P83731,P09234,P62750,P62841,Q9H0A0,Q9NVP1,Q15056,Q13823,Q99590,O60832,O76021,P63173,Q12788,Q14684,Q9BY44,Q9BYG3,Q9H0S4,Q9UNQ2,Q9Y2P8,Q9Y2R9,Q9BZE4,P39023,Q9H9Y2,Q9Y312,Q13895,Q15637,Q06265 116 +Mitochondrial fusion 0.2864057081707878 0.1714628369387502 0.8638598494949001 1.0 1.0 15 Q9UJZ1,Q8TB36,Q07812,O95140 4 +Positive regulation of cellular amide metabolic process 0.2401433847794523 0.1710674117985649 0.8641707597370232 1.0 1.0 72 Q9NYY8,P42574,Q9Y5A9,Q9BRT2,P16989,Q9BY77,Q7Z478,Q567V2 8 +Small gtpase mediated signal transduction 0.2798250574350459 0.1707018437181714 0.8644582130312735 1.0 1.0 101 P53365,O95140,Q99653,O75962,Q9NWH9,P62330,Q07960,Q9Y624,P60953,Q5VZ89,P41440,Q15382 12 +Actin filament based transport 0.3058889848668238 0.1706468717329684 0.8645014401252724 1.0 1.0 8 O00159,O43795 2 +Negative regulation of protein localization to nucleus 0.2916566431519343 0.1706119378096419 0.8645289105461849 1.0 1.0 9 Q99653,Q9UHD1,Q96ST3 3 +Sodium ion transmembrane transport 0.2897434444762055 0.1694752881700645 0.8654228083735456 1.0 1.0 21 Q9HD47,Q99653,Q9UHD1,P54709,P08195 5 +Positive regulation of glial cell proliferation 0.6337051552607733 0.1682156197311024 0.8664136532711648 1.0 1.0 2 O94874 1 +Postsynapse organization 0.2767632211453056 0.1681426295684373 0.8664710731871892 1.0 1.0 32 P62330,O15020 2 +Mrna methylation 0.3180559823133013 0.1680791992042395 0.8665209731713222 1.0 1.0 7 Q15007,Q9UJA5,Q7L0Y3,Q69YN4,Q08J23 5 +Regulation of mrna catabolic process 0.2598464200706549 0.1680450171912899 0.8665478640132476 1.0 1.0 87 Q9NYY8,Q7L8L6,O75175,Q8TCS8,Q13868,Q9Y5A9,Q16539,Q969Z0,P31749,P16989,Q6P6C2 11 +Single fertilization 0.2866258134319247 0.1678728037983437 0.8666833458943863 1.0 1.0 26 P55769 1 +Stress granule assembly 0.2883702179220521 0.1670513419210019 0.8673296514429463 1.0 1.0 20 Q9Y5A9 1 +Organelle fusion 0.2111121602414579 0.1670240798136711 0.8673511021064411 1.0 1.0 48 Q9NVJ2,Q92930,O75396,O95140,P61006,Q07812,Q86Y82,P51809,P78356,P51153,Q9BZG1,Q9UJZ1 12 +Organophosphate ester transport 0.2864974001189714 0.1657616244379764 0.8683445475098657 1.0 1.0 25 O15439,Q9BSK2,P41440,Q8TB61 4 +Cell cell adhesion 0.2731493767220606 0.1648011450594887 0.8691005027394603 1.0 1.0 98 Q9HCM4,Q9Y5A9,P10586,P35613,P31749,Q13740,Q9Y624,Q9HCL2,P41440 9 +Regulation of embryonic development 0.2861387849360387 0.1646240209530452 0.8692399231886365 1.0 1.0 18 Q9Y4C8 1 +Mesenchymal to epithelial transition 0.3725975426372369 0.1643054388642498 0.8694907002886865 1.0 1.0 4 P35222,P80723 2 +Organic acid catabolic process 0.2455089647455581 0.1634668664794346 0.8701508589403317 1.0 1.0 78 A1L0T0,P00505,O43808,P38117,P40939,P30038,P26440,Q9UJ83,Q92947,Q9BUT1,P52758,Q4G176,Q8TD30,P42126,P31749,P25325,P55084,P36957,P23786,P05165,O15382,Q96RQ3,P34896 23 +Endoplasmic reticulum localization 0.4164656212304051 0.1631437221515206 0.8704052756196343 1.0 1.0 3 O95292,A0FGR8 2 +Endoplasmic reticulum plasma membrane tethering 0.4164656212304051 0.1631437221515206 0.8704052756196343 1.0 1.0 3 O95292,A0FGR8 2 +Cell fate commitment 0.2865809327594725 0.1631174423789853 0.870425966693479 1.0 1.0 21 P42574,P61026,Q07820,P61586,P60953,Q92541,Q92974 7 +Protein homooligomerization 0.2309987196473769 0.1628332633824903 0.8706497173900307 1.0 1.0 44 Q99720,Q8TCS8,Q99797,P54132,O43633,P34896,P04179,Q9UN86,Q9H8V3,Q96CX2,P14174 11 +Regulation of intracellular signal transduction 0.2079995763946978 0.1626140803290778 0.8708223000637723 1.0 1.0 304 Q8N2F6,P62841,O14641,Q3LXA3,Q9NY93,Q9Y624,P30405,P41440,P46734,Q15382,O75787,O75340,O95140,Q99653,Q07820,P60953,P42858,Q01085,Q9NZM5,Q9NUD5,Q5VZ89,Q9H6R0,Q8TB61,O60826,Q9NWH9,Q16539,P31749,P16989,O43324,Q02952,O75962,P14174,Q9H7B2,Q86Y07,P62330,P04179,Q07960,Q96QC0,Q969S3,Q9P0J0,Q9Y6D9 41 +Regulation of telomerase activity 0.2855451814416705 0.1622512756894638 0.8711079825371426 1.0 1.0 19 Q15185,Q9BUR4,Q96BK5,P17987,P35222,O60832 6 +Protein acylation 0.2222807223041557 0.1618670240297863 0.8714105713283375 1.0 1.0 62 P36957,Q49A26,Q12824,Q00403,P09622,Q02218,Q9NRA0,Q9UBU8,P51608,Q969T9,Q96ST3,Q9HAF1,Q9H0A0,Q9GZZ1,Q9NPF5,Q5VZE5 16 +Blood vessel endothelial cell migration 0.2852236865078285 0.1618624490571006 0.8714141741209818 1.0 1.0 24 Q5JRA6,Q16539,P51608,P61586,P31749,P78536,O94813,P46734,P14923 9 +Cell matrix adhesion 0.2687550674344304 0.1617927501062758 0.871469062399852 1.0 1.0 34 Q9HCM4,P05556,Q9Y2S7,Q9UM22,Q9P258,Q9UPN3,P42771,P63167,P61586,O75122,P46939,Q9ULV4,P35222,P14923,Q13418 15 +Regulation of ubiquitin protein ligase activity 0.2764199461638214 0.1615648713101562 0.8716485224314554 1.0 1.0 12 P60866,P62841 2 +Mitochondrial outer membrane permeabilization 0.271945966134803 0.1614113543939616 0.8717694244199938 1.0 1.0 10 P05141,Q9UII2 2 +Regulation of protein containing complex disassembly 0.2301843251270221 0.1608370470211659 0.8722217457686634 1.0 1.0 44 Q9UHB6,Q9Y281,Q8WWK9,O75122,O15020 5 +Exocytosis 0.251091373711672 0.1605579877752904 0.8724415463986688 1.0 1.0 83 Q92930,P35080,Q7Z6M1,O15439,Q9Y2D4,Q9BRK5,P20339,O75122,P51153,Q8N5M9 10 +Hematopoietic progenitor cell differentiation 0.281722209689468 0.160182215201433 0.8727375387046044 1.0 1.0 27 P11388,A0AV96,Q9H2U1,O43809,Q9Y5A9,Q9Y520,Q96ST3,Q9Y3A5 8 +Leukocyte apoptotic process 0.2847559001545173 0.1596138167810099 0.8731852943117093 1.0 1.0 22 P42574,P31749,Q9HCL2,P14174,P78536 5 +Peptidyl lysine acetylation 0.2036282280348693 0.158641826292583 0.8739510734492992 1.0 1.0 50 Q49A26,Q12824,Q00403,Q9NRA0,Q9UBU8,P51608,Q969T9,Q96ST3,Q9HAF1,Q9GZZ1,Q9NPF5 11 +Protein import into mitochondrial matrix 0.3002114164904874 0.1585566924173117 0.874018151495169 1.0 1.0 8 O94826,Q3ZCQ8,O43615,Q9HAV7,Q99595,O14925,O96008 7 +Regulation of actin filament based process 0.2712619665084322 0.1583387142544308 0.874189903343978 1.0 1.0 99 Q9UHB6,Q9Y281,P35080,P53365,Q9HD47,Q9NWH9,P62330,O15144,Q9Y624,Q13576,P60953,O15020,O75122,Q9Y613 14 +Negative regulation of intracellular signal transduction 0.2852518485296825 0.1583007759707274 0.8742197967165526 1.0 1.0 110 O75340,Q8N2F6,O60826,O95140,Q99653,Q9NWH9,Q16539,Q3LXA3,Q07820,P04179,P31749,Q96QC0,P16989,Q9NZM5,P30405,P14174,P46734 17 +Vesicle mediated transport between endosomal compartments 0.2840469482442654 0.1582581763060742 0.8742533632261678 1.0 1.0 22 Q9UMY4 1 +Transport along microtubule 0.2121636479412132 0.1581315666695141 0.874353126933481 1.0 1.0 56 Q9NVJ2,Q15554,P60953,P42858,P62820,O94901 6 +Serine family amino acid biosynthetic process 0.2855658061536174 0.1580593920972303 0.8744099987189402 1.0 1.0 9 P78330,Q9Y617,P34896 3 +Regulation of cellular macromolecule biosynthetic process 0.1972573624569371 0.1573078057246102 0.8750022687722114 1.0 1.0 285 Q9BXS4,Q15554,Q9UI10,Q7Z6E9,Q9BY77,Q9ULV3,Q9H0A0,Q567V2,P31483,Q9NYY8,Q8TCS8,Q15056,Q99653,Q9Y5A9,Q96EY7,O60934,P60953,Q7Z478,O60832,O75175,P63173,Q13868,Q13148,Q9BSH4,Q9BRT2,Q9BY44,P31749,P16989,Q9HAF1,P62140,P46100,P54132,Q96BK5,P0CG13,P34896,Q9UKZ1 36 +Aldehyde catabolic process 0.3255468393754606 0.1570942993345768 0.8751705302731043 1.0 1.0 6 Q16775 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 1.0 3 P10321 1 +Activation of adenylate cyclase activity 0.4122024653196161 0.1555243801697156 0.8764079351842238 1.0 1.0 3 P40123 1 +Regulation of t cell proliferation 0.2794299329124641 0.1553843762465938 0.8765183005158301 1.0 1.0 16 P42574,Q9HCL2,Q9Y6D9 3 +Positive regulation of double strand break repair 0.2824611020141488 0.1552489153699628 0.8766250868415133 1.0 1.0 21 P61160,P09874,Q9UBU8,Q9HAF1,Q9NPF5,A6NHR9,Q8TAF3 7 +Regulation of leukocyte migration 0.2777152259356195 0.1549476151552182 0.8768626154484742 1.0 1.0 28 Q07021,Q5JRA6,P61586,Q8NE86,P31749,P30046,O94813,P14174,P78536 9 +Regulation of microvillus organization 0.3677224736048286 0.1548493202305755 0.8769401081899681 1.0 1.0 4 P15311,Q6IBS0,Q16658 3 +Regulation of cell projection size 0.3677224736048284 0.1548493202305749 0.8769401081899686 1.0 1.0 4 P15311,Q6IBS0,P07196 3 +Glutamate metabolic process 0.2707880937985152 0.1548413332857677 0.8769464049071756 1.0 1.0 11 P30038 1 +Mrna processing 0.3231329660767928 0.1545330940577523 0.8771894193245349 1.0 1.0 275 Q96T37,Q86V81,P55769,Q86W42,Q07021,O95391,Q15428,P08621,O94906,P52272,Q92879,Q9BWJ5,Q96BP3,Q9Y4C8,Q9UNP9,Q9NWH9,P08579,P62312,Q15427,Q8TBF4,Q9BUQ8,Q9NW13,Q9NW64,Q8WXA9,P31483,Q13247,Q7L8L6,Q12972,Q5T8P6,P57678,Q9ULR0,P62318,P62314,Q8IY67,Q6P2Q9,Q96DI7,O75475,Q969Z0,O95400,Q8IWZ8,Q6P6C2,Q9H2U1,Q9UKA9,Q15233,Q9UMS4,Q9UNY4,Q86U42,P09012,O60306,Q8TCS8,Q9ULX6,Q15424,Q9BTD8,Q8IX01,Q7L014,Q13148,O43809,Q14690,Q13435,Q9BZJ0,Q9BZL1,Q9H2H8,O00148,Q9Y3C6,P62304,Q8NI27,Q8IYB3,Q86UA1,Q5VTL8,P09234,Q96DF8,Q96I25,Q7Z6E9,O75643,Q13242,Q12849,Q13595,Q99590,P33240,Q14151,Q14684,Q92620,Q9H0S4,Q9P2N5,Q9Y312,Q15637 86 +Animal organ morphogenesis 0.2666110294876018 0.1544315558880219 0.877269474095447 1.0 1.0 97 Q13247,Q96T37,P11047,Q16706,O95140,P35613,O14641,Q16539,O60568,P60953 10 +Metal ion export 0.3117203885634265 0.154426540680191 0.8772734282204726 1.0 1.0 7 O95202,P54709 2 +Deoxyribonucleoside monophosphate metabolic process 0.2836597334525497 0.1543043034613818 0.8773698042850724 1.0 1.0 9 P34896 1 +Organelle assembly 0.2240227707824132 0.1539587647731571 0.8776422488037057 1.0 1.0 273 P83731,P53365,Q02878,Q9HA65,O15439,P61006,Q15286,P62750,P62841,P62857,Q567V2,P82912,Q9Y6A4,Q9Y3A5,P31483,Q9Y496,Q9NYY8,Q07021,O75695,O75396,O95140,Q9Y5A9,P46087,Q9Y4P1,O75616,P42858,Q7Z478,Q9NZM5,P63173,Q9Y2S7,Q5MNZ6,Q9BY44,P82094,P20339,O75122,P78356,Q9Y2R9,Q9BZG1,Q9H7B2,Q9NQS7,Q92930,Q9NVJ2,Q9Y281,P39023,O75083,P57076,Q86Y82,P28289,Q99700,P50748,Q9Y5K8,P62820,Q9NUL7 53 +Regulation of protein localization to membrane 0.2032471677640104 0.153915968670487 0.8776759929625202 1.0 1.0 51 Q99653,P31749,P62330,Q9BXS4 4 +Negative regulation of histone h4 acetylation 0.4110373944511551 0.1534842066714457 0.8780164439898805 1.0 1.0 3 Q96EB6,Q9NWS0 2 +Peptidyl amino acid modification 0.193761498333796 0.153400759838601 0.8780822457143609 1.0 1.0 271 O75367,Q12824,P04844,P16403,P16402,O14641,Q96L73,Q96ST3,P30405,Q9Y6A4,P46734,P45877,Q5VZE5,Q96JJ7,P10412,Q9Y5S2,Q13610,O60568,Q9NPF5,Q13162,P35080,Q96BP3,Q9NWH9,Q16539,P31749,Q9HAF1,P14174,Q9H2H8,P78536,Q86Y07,P46100,P26885,Q9Y3C6,Q9Y673,Q969T9,Q49A26,Q9Y237,Q99986 38 +Glycolytic process through fructose 6 phosphate 0.2830815709969727 0.1531815499302439 0.8782551069752762 1.0 1.0 9 P19367,P09104,P17858,P51570,Q01813,P08237,P52789,P06733 8 +Negative regulation of fibroblast proliferation 0.3375261221403718 0.153044080353435 0.878363513633794 1.0 1.0 5 P04179 1 +Histone deacetylation 0.2779082852522962 0.1528804257432081 0.8784925724309784 1.0 1.0 27 Q9ULM3,Q92769,Q13330,Q9ULX6,Q9NRA0,Q9H4L7,Q9UBU8,Q14839,Q96ST3,O94776,Q9BZK7,Q16576 12 +Chromatin disassembly 0.271667814257963 0.1526277134010793 0.8786918689171284 1.0 1.0 12 Q9Y5B9,Q12824,Q92922,Q9BQ67,Q8TAQ2,Q66K74,P17096,P51532 8 +Renal system process 0.2716429477378486 0.1525824091821714 0.8787275979875762 1.0 1.0 12 P17612,Q9NQH7,Q7LG56,P61586,O76024,Q0IIM8 6 +Regulation of phosphoprotein phosphatase activity 0.2778433809255685 0.1524842756155951 0.8788049916511809 1.0 1.0 16 Q5H9R7,P42858 2 +Atp metabolic process 0.2845228952358071 0.1508688992240981 0.8800791344486765 1.0 1.0 113 P56134,O75438,P04406,P09874,O43676,P48047,P61586,P30405,Q9UJZ1,Q9UDW1,P19404,Q02218,Q9NRA0,P28331,P14927,O14548,P20674,Q9BRT2,O75380,P08574,P03915,O95139,O95168,Q9BSK2,Q16795,Q9UII2,O14949 27 +Energy reserve metabolic process 0.2786858502043898 0.1506319160137684 0.8802660833077394 1.0 1.0 18 P31749,P62140 2 +Response to leukemia inhibitory factor 0.2702162617373146 0.150538560759242 0.8803397302663467 1.0 1.0 31 Q8NFH5,P34896,O43324,O15382 4 +Positive regulation of neurotransmitter secretion 0.6213445884835678 0.1501118942128403 0.8806763360921184 1.0 1.0 2 Q00535 1 +Calcium ion regulated exocytosis of neurotransmitter 0.6213445884835663 0.1501118942128384 0.8806763360921199 1.0 1.0 2 P16615 1 +T cell proliferation 0.2782955755695736 0.1489121085825474 0.8816229864813179 1.0 1.0 24 P42574,Q07812,Q9HCL2,Q9BY67,Q9Y6D9 5 +Regulated exocytosis 0.2498344227551597 0.148733951674521 0.881763569636661 1.0 1.0 38 Q9NVJ2,P35080,O15439,Q99584,Q9BRK5,P20339 6 +Synaptic vesicle clustering 0.6201386795296924 0.1484218064501814 0.8820098916044794 1.0 1.0 2 P35222 1 +Detection of muscle stretch 0.6201386795296924 0.1484218064501814 0.8820098916044794 1.0 1.0 2 P35222 1 +Regulation of heart rate 0.2690503021476393 0.147941770414561 0.8823887228684117 1.0 1.0 12 Q14126,Q9HD47,Q99996,P15924,P14923,P16615 6 +Response to mitochondrial depolarisation 0.3085526092222014 0.147895134335424 0.8824255282173048 1.0 1.0 7 O95140 1 +Tripartite regional subdivision 0.3637525493270023 0.1474163105260656 0.8828034322310274 1.0 1.0 4 P80723 1 +Blastoderm segmentation 0.3637525493270023 0.1474163105260656 0.8828034322310274 1.0 1.0 4 P80723 1 +Positive regulation of immune effector process 0.2455203637334317 0.1473835412342542 0.8828292958453827 1.0 1.0 39 Q92614,Q9NR30,Q5RKV6,Q9NY93,P51809,P39019,P04439,Q9BY67,P14174 9 +Regulation of oxidoreductase activity 0.2778147643430307 0.147281555270635 0.8829097904693584 1.0 1.0 20 P31749,Q15554 2 +Microtubule based transport 0.2087572770547691 0.1467513151794862 0.8833283133769971 1.0 1.0 57 Q9NVJ2,Q15554,P60953,P42858,P62820,O94901 6 +Rna splicing 0.3237196094069804 0.145728860634259 0.8841354370892376 1.0 1.0 243 Q96T37,Q86V81,P55769,Q86W42,Q07021,O95391,Q15428,P08621,O94906,P52272,Q92879,Q9BWJ5,Q96BP3,Q9Y4C8,Q9UNP9,P08579,P62312,Q15427,Q8TBF4,Q9BUQ8,Q9NW13,Q9NW64,P24928,Q8WXA9,P31483,Q13247,Q12972,P57678,Q9ULR0,P62318,P62314,Q8IY67,Q6P2Q9,Q96DI7,O75475,O95400,Q8IWZ8,Q8IXT5,Q9UKA9,Q15233,Q9UMS4,Q9UNY4,P09012,O60306,Q9ULX6,P62854,Q9BTD8,Q8IX01,Q7L014,Q9Y3I0,Q13148,Q13435,Q9BZJ0,Q9BZL1,Q9H2H8,O00148,Q9Y3C6,P62304,Q8NI27,Q8IYB3,Q86UA1,Q5VTL8,P09234,Q96DF8,Q96I25,Q09666,O75643,Q13242,P62277,Q05519,Q12849,Q13595,Q99590,Q13523,Q96RS0,Q9UKM9,Q14684,Q9Y224,Q92620,Q9H0S4,Q9Y312,Q15637 82 +Protein depolymerization 0.2134395521812736 0.1456540695830449 0.8841944817362806 1.0 1.0 46 Q9UHB6,Q9Y281,Q8WWK9,O75122,O15020 5 +Posttranscriptional regulation of gene expression 0.1989330664391781 0.1450363194824131 0.8846821961548843 1.0 1.0 241 Q9HCM4,Q9UI10,Q8NHU6,Q9BY77,Q9H0A0,Q567V2,P31483,Q9NYY8,Q07021,Q7L8L6,Q8TCS8,Q15056,Q9Y5A9,Q96EY7,P52272,Q96B26,Q7Z478,Q01085,O60832,O75175,Q9Y6V7,P63173,Q13868,Q13148,Q9BSH4,O43809,Q9BRT2,Q16539,Q9BY44,P31749,P16989,P34896,Q969Z0,Q99700,Q6P6C2,Q9UKZ1,Q06265 37 +Positive regulation of gene expression 0.1947727713030387 0.1450363193855622 0.8846821962313516 1.0 1.0 241 Q9NW64,O75367,Q9NY93,Q15554,Q99584,Q9BY77,Q9H0A0,Q567V2,P41440,O75787,Q9NYY8,Q9ULK4,Q9Y5A9,Q7Z478,Q9NUD5,Q9H6R0,Q13148,Q9BRT2,Q16539,P82094,P31749,P16989,Q02952,Q9BY67,P14174,P78536,Q5RKV6,Q969T9,P62820 29 +Actin filament organization 0.2827774974363146 0.1448442051794629 0.8848338795359112 1.0 1.0 115 Q8N8S7,Q9UHB6,Q9Y281,P35080,P53365,Q9Y3C0,Q9NWH9,P62330,O15144,Q9Y624,Q13576,Q8NE86,O15020,P60953,O75122,Q9Y613 16 +Positive regulation of protein polymerization 0.2670234701096172 0.1447620737537975 0.8848987274917393 1.0 1.0 31 P35080,Q9NWH9,Q99996,P62330,O15144,P51608 6 +Negative regulation of cell morphogenesis involved in differentiation 0.4056519537895112 0.1442887688260036 0.8852724466822683 1.0 1.0 3 Q9P258 1 +Antigen processing and presentation of endogenous peptide antigen 0.3192148594820634 0.1437061181734138 0.8857325397474776 1.0 1.0 6 Q03518,P10321 2 +Antigen processing and presentation of endogenous antigen 0.3192148594820634 0.1437061181734138 0.8857325397474776 1.0 1.0 6 Q03518,P10321 2 +Porphyrin containing compound metabolic process 0.2738170084483666 0.1436519441584766 0.8857753204951015 1.0 1.0 17 P22830,Q9BUT1,Q5T440,Q9UII2 4 +Regulation of cd40 signaling pathway 0.6165209526680705 0.1434325069524326 0.8859486115491964 1.0 1.0 2 Q9BXW9 1 +Regulatory t cell differentiation 0.6165209526680705 0.1434325069524326 0.8859486115491964 1.0 1.0 2 Q9BXW9 1 +Regulation of protein localization to plasma membrane 0.2591207269032003 0.1431270747351594 0.8861898225261535 1.0 1.0 34 P31749,P62330,Q9BXS4 3 +Aromatic amino acid family metabolic process 0.3181206875654316 0.141467055507597 0.8875009841665262 1.0 1.0 6 Q92947,P16930 2 +Respiratory gaseous exchange by respiratory system 0.263167298181571 0.1413941286218688 0.8875585923547828 1.0 1.0 11 P51608,Q16706 2 +Positive regulation of protein localization to cell periphery 0.274297625724599 0.1410161457074875 0.8878571873698717 1.0 1.0 22 P31749,P62330 2 +Zymogen inhibition 0.403634561580159 0.1409436821572553 0.8879144331917279 1.0 1.0 3 O15446 1 +Scf dependent proteasomal ubiquitin dependent protein catabolic process 0.3046497584541036 0.1401189122089047 0.8885660382201863 1.0 1.0 7 Q13616,Q15058,P63208,Q93034,Q13617,Q13620 6 +Kinetochore organization 0.3042881472527109 0.1394135525101349 0.8891233635870088 1.0 1.0 7 P50748,O95347 2 +Regulation of fc receptor mediated stimulatory signaling pathway 0.4022433315915286 0.1386684425413803 0.8897121563296881 1.0 1.0 3 Q9UKG1 1 +Cardiac muscle contraction 0.2722079191192096 0.1386379149098416 0.8897362808441456 1.0 1.0 19 P17612,Q9HD47,Q99996,P15924,Q14126,P46734,P14923,P16615 8 +Regulation of protein k63 linked ubiquitination 0.3301146650573276 0.1384601468768412 0.8898767643722345 1.0 1.0 5 Q96FW1,P61088,O00571,Q14669 4 +Interleukin 6 production 0.2649683361597549 0.1379395267071759 0.8902882111907942 1.0 1.0 13 Q06124,Q9NRA0,P17655,Q08722 4 +Long chain fatty acid biosynthetic process 0.4016887816646638 0.1377687082897748 0.8904232156586427 1.0 1.0 3 P28161,O00154 2 +Positive regulation of golgi to plasma membrane protein transport 0.6123002713295116 0.1377647910900539 0.8904263116118767 1.0 1.0 2 O95573 1 +Ovulation cycle 0.2584069377042279 0.1372674006445217 0.8908194370025799 1.0 1.0 10 P42574,O94813 2 +Regulation of cell substrate adhesion 0.2321410549000545 0.1370483961989406 0.8909925413418585 1.0 1.0 41 Q9HCM4,Q07021,Q9Y2S7,P42771,O15144,P61586,O75122,P46939,P60953 9 +Endothelial cell proliferation 0.2710535024148502 0.136809601118651 0.8911812944111588 1.0 1.0 19 P31749,O75340,P78536 3 +Myeloid leukocyte activation 0.271115284924093 0.1362644697578003 0.8916122108736904 1.0 1.0 23 Q92614 1 +Neural tube formation 0.2710936353149016 0.1362265935788754 0.8916421524975582 1.0 1.0 20 P42574,P62081,O14641,Q13308 4 +Positive regulation of multicellular organismal process 0.2086986082574668 0.1361254407519976 0.8917221159114501 1.0 1.0 209 O75367,P04406,P09874,Q9H2U1,Q9NY93,Q99584,Q68CQ4,P61586,P51809,Q9UMS4,P40939,P39019,P52789,Q9UGM6,P41440,Q9UJZ1,Q15382,O75787,O75340,Q07021,P20020,O95140,Q9NRA0,O94813,Q9NUD5,Q9H6R0,P08069,P14923,Q16706,O75175,Q9NR30,P61160,Q9Y4C8,Q16539,P82094,P31749,P16989,Q02952,P04439,Q9BY67,P14174,P78536,Q9UKG1,Q92930,P23786,P80723,Q5SW96,Q9P0M6,Q5RKV6,Q86UE4,O96013,P30046,Q9HCL2,P62820 54 +Positive regulation of sodium ion transmembrane transporter activity 0.273548296405634 0.1357529597405188 0.8920165793857413 1.0 1.0 9 Q99653 1 +Pentose phosphate shunt non oxidative branch 0.6104914078987007 0.1353861053797912 0.8923066092868135 1.0 1.0 2 P29401 1 +Rna splicing via transesterification reactions 0.3294174080799906 0.1353458804424917 0.8923384114338826 1.0 1.0 189 Q9NW64,Q96T37,P09234,Q86V81,P55769,P09012,P31483,Q13247,Q07021,O95391,Q15428,P08621,Q13595,O94906,P52272,Q99590,Q92879,Q9BWJ5,Q9ULR0,Q9BTD8,Q96BP3,Q9Y4C8,Q9UNP9,Q92620,P62314,P08579,P62312,Q9BZJ0,Q9BZL1,Q9H2H8,Q9Y3C6,Q96DI7,Q15427,Q8TBF4,O95400,Q9Y312,Q15637 37 +Regulation of body fluid levels 0.2030448079852629 0.1353333338137689 0.8923483309311819 1.0 1.0 47 Q9Y624,Q9NWH9,Q9UIJ7 3 +Neural tube development 0.2673397653340862 0.1349190951993105 0.8926758418074918 1.0 1.0 27 P42574,O14641,O60568,Q13308,O75787 5 +Regulation of mitochondrial membrane permeability involved in apoptotic process 0.2591685178441254 0.1348940838931978 0.892695617167536 1.0 1.0 11 P05141,Q9UII2 2 +Embryo development 0.2432356266560278 0.1347372432995668 0.8928196257748646 1.0 1.0 204 Q9HCM4,O75367,Q13503,Q12824,P42574,O14641,Q15554,Q7Z6E9,Q68CQ4,Q8NHU6,Q9Y3Y2,Q96ST3,Q71F23,Q9Y3A5,O75787,O75340,Q9Y6I3,O95140,Q9Y5A9,O60934,P62081,O60568,P60953,Q16706,P26373,O75175,P17655,P63173,Q9Y4C8,P31749,P16989,O75122,Q13308,Q9H9Y6,Q8TAF3,Q9Y3C6,P80723,Q6DKI1,O43819,Q9BZK7,Q9H488,Q13895 42 +Cellular amino acid biosynthetic process 0.2588678083958201 0.1346774610555315 0.8928668942840594 1.0 1.0 32 A1L0T0,P00505,Q96C36,O15382,P34896,P78330,P32322,Q9Y617,O60568 9 +Cellular component assembly involved in morphogenesis 0.2701074895817048 0.1343885722056603 0.893095317721726 1.0 1.0 22 P28289,Q9Y281,O75122,P82094 4 +Regulation of vasculature development 0.2511801921684492 0.1343646358149062 0.8931142445431324 1.0 1.0 35 Q9UGM6 1 +Regulation of immune system process 0.2146900292077472 0.1338995742739064 0.8934819869349375 1.0 1.0 201 Q96T37,Q92614,Q8TCT8,Q9Y5A9,Q16539,Q3LXA3,P14174,Q9UI10,P31749,P62805,Q8NE86,Q9NX58,Q9HCL2,Q9NZM5,Q9NUD5,P41440 16 +Mitochondrion organization 0.2911131573036888 0.1338688538184094 0.893506279610591 1.0 1.0 200 P53365,O75438,O43676,P30405,Q8TCS8,O95140,Q8IUX1,Q9Y4P1,Q8NE86,P42858,P28331,Q96CU9,Q9NS69,O14548,Q16706,Q9Y2S7,Q9BSH4,Q86Y39,Q5MNZ6,Q9BRT2,P31749,Q5HYI7,P03915,Q9BZL1,Q5TC12,O95139,O43819,O95168,P04179,O60220,Q9NX47,Q00059,Q9NVT9,Q9BSK2,Q9P0J0 35 +Negative regulation of gtpase activity 0.2723533549263235 0.1337114586562058 0.8936307438378317 1.0 1.0 9 Q9P258,P35241,Q9Y624,Q14684 4 +Regulation of lipid localization 0.2675810928964212 0.133698229281102 0.893641205422012 1.0 1.0 26 P31749,P82094 2 +Cytokine production 0.2601515316958679 0.1326162786877597 0.8944968576075973 1.0 1.0 104 P17655,O75787,Q16539,Q9NY93,P14174,P82094,P62820,Q9Y624,Q9HCL2,Q02952,Q9NUD5,Q9H6R0,P41440,P46734,P78536,P31483 16 +Positive regulation of developmental process 0.2037870430385264 0.1325085524301226 0.8945820588152293 1.0 1.0 196 O75367,O14641,Q9Y624,Q9UGM6,P41440,Q15382,O75340,Q13610,O15144,Q8NE86,P60953,Q16706,P17655,Q9Y4C8,O43809,Q16539,P31749,P16989,O75122,O43324,Q9P0M6,Q5RKV6,Q9NX47,Q9HCL2 24 +Amino acid activation 0.2437006591064035 0.132060565017364 0.8949363872172431 1.0 1.0 37 Q5T160,Q9BW92,Q15031,Q5ST30,Q5JTZ9,Q9Y285,Q9NP81,Q9UGM6 8 +Epithelial cell differentiation 0.2684527985774928 0.1320584147183805 0.8949380880120708 1.0 1.0 112 Q9HCM4,O43347,P11047,Q13247,P46100,Q9P0M6,Q9NWH9,P31749,Q9Y624,O60568,P60953,P51153,Q9Y2Q3,P62820,Q15382 15 +Mammalian oogenesis stage 0.6077781127524806 0.1318745279775397 0.895083536370739 1.0 1.0 2 P62753 1 +Negative regulation of developmental process 0.2581342145606636 0.1316474564861178 0.895263147311931 1.0 1.0 103 Q13247,Q96T37,Q9Y6I3,Q9Y5A9,P62330,Q15554,P62805,Q9NX47,O75962,P14174 10 +Myeloid cell homeostasis 0.2327741957133731 0.1314909080299144 0.8953869784698243 1.0 1.0 40 P08708,Q9UII2,P05141,P42574,Q16539,Q07812,P62753,P62847,Q9NX58,P39019,P78536 11 +Regulation of short term neuronal synaptic plasticity 0.6074766355140134 0.1314885263313285 0.8953888624333184 1.0 1.0 2 Q15042 1 +Generation of precursor metabolites and energy 0.3044317824173596 0.1314005165584809 0.8954584800521423 1.0 1.0 187 P56134,O75438,P50213,P04406,O43676,P22830,P48047,P38117,P61586,Q96I99,Q99798,P30405,P30038,Q6FI81,Q9UJZ1,Q9UDW1,P10515,P19404,P09669,Q8TCS8,Q02218,Q9NRA0,Q04446,P08559,P28331,Q9NZM5,P14927,O14548,P55809,P20674,Q9BSH4,Q9BRT2,O75380,P31749,P08574,P03915,P23368,P36957,P62140,O95139,O43819,Q9BSK2,O95168,P04179,Q9P0J0,P22570,Q9P2R7,Q16795,Q9UII2,O14949 50 +Regulation of phosphatase activity 0.2676742118137934 0.1310445996131132 0.8957400261990716 1.0 1.0 20 Q99653,Q5H9R7,P42858 3 +Positive regulation of lamellipodium organization 0.2620641951884592 0.1308908233667514 0.8958616741196763 1.0 1.0 14 P60953 1 +Positive regulation of transport 0.2144141294737729 0.1308402766026617 0.8959016607309742 1.0 1.0 190 Q92930,Q9NW64,P55809,Q92614,Q99653,P62330,Q16539,P82094,P14174,P31749,Q8NE86,P20339,Q9NX58,P42858,P60953,Q9NPF5,P41440 17 +Cell junction organization 0.2782735871276595 0.1307009356859325 0.8960118921251203 1.0 1.0 123 Q92930,Q9HCM4,P11047,P35080,Q9Y2S7,P62330,P10586,Q16539,Q9BRK5,Q9Y624,P60953,O15020,P51153,P41440 14 +Rna localization 0.2721554849126348 0.1306108868775896 0.8960831300266543 1.0 1.0 117 P22087,Q9H2U1,Q9HAU5,Q86V81,P37198,Q9UKX7,P49790,Q9Y3Y2,Q9BY77,Q86U42,P41440,Q86W42,O00159,Q8TCS8,Q9ULX6,O94906,Q9UN86,P82979,Q9Y6M1,Q5SRE5,Q9BTX1,O60832,O75152,P78406,Q8NFH5,Q99700,Q6P6C2,Q8NI27,Q8TEM1 29 +Spindle localization 0.2675556245312417 0.1305723050414916 0.8961136524975535 1.0 1.0 21 P42858 1 +Supramolecular fiber organization 0.2003545445101349 0.1302836598378367 0.8963420074390793 1.0 1.0 188 Q8NBJ5,P53365,Q9Y3C0,Q9Y624,O15020,Q99653,O15144,Q8NE86,Q13576,O60568,P60953,Q8N8S7,Q9UHB6,P35080,Q9HD47,Q9NWH9,O75122,Q9Y281,P62330,Q8WWK9,Q9Y613 21 +Maintenance of protein location 0.2559141995823365 0.1301710524058 0.8964310965203317 1.0 1.0 32 P31749,O60826,Q9ULV3 3 +Positive regulation of protein localization to membrane 0.2557491837335554 0.1299272977415077 0.8966239468696897 1.0 1.0 32 Q99653,P31749,P62330 3 +Positive regulation of cell cycle process 0.2307330999700999 0.1299184034857282 0.896630983816076 1.0 1.0 81 O75367,P37198,P61586,Q96ST3,P43487,P51608,P60953,P08069,P35241,Q9Y2S7,P31749,O60216,Q7Z7K6,P78536,P46100,Q8N122,Q7LG56,Q96DE0,Q96QC0,Q9H8V3,Q9Y6D9 21 +Rna polyadenylation 0.261253683450074 0.1298209978398544 0.8967080496276219 1.0 1.0 29 O43809,Q8TCS8,P09012 3 +Actin filament based process 0.2609441419003128 0.1295307198938084 0.8969377187393301 1.0 1.0 185 Q8N8S7,Q9HCM4,Q9NVU7,Q92614,P53365,P35080,Q9HD47,Q9Y5S2,Q9NWH9,P62330,Q9Y624,Q13576,Q8NE86,O15020,P60953,P51153,Q9Y613 17 +Regulation of cell adhesion 0.2481804547459984 0.129474121272159 0.896982500809558 1.0 1.0 96 Q9HCM4,P42574,P61586,Q9Y624,P46939,P41440,Q07021,Q99797,Q9Y5A9,P42771,O15144,P60953,P14923,Q9Y2S7,Q16539,P31749,O75122,P04439,Q9BZE4,P62140,Q5JRA6,Q9HCL2,Q9Y6D9 23 +Cell morphogenesis 0.2106465925640674 0.1294499749753985 0.8970016059887747 1.0 1.0 185 Q8N8S7,Q9HCM4,P11047,Q9Y5A9,Q9NWH9,P35613,O14641,P62820,Q13740,Q9Y624,O60568,P60953,O75962,P41440 14 +Regulation of protein polymerization 0.2101471623635834 0.1294245586386217 0.8970217161212595 1.0 1.0 65 P35080,Q9HD47,Q9NWH9,P62330,O15144,P28289,O15020 7 +Growth 0.2314985248880386 0.128623133956241 0.8976558601107345 1.0 1.0 182 Q9HCM4,Q8N2F6,Q7Z6E9,Q13740,Q96ST3,O15020,O43909,P11047,Q8TCS8,Q15056,P42771,O60934,P60953,Q9NPF5,Q9Y6V7,Q13868,Q16539,P31749,P16989,Q9HAF1,Q13308,Q05086,Q8TAF3,P78536,P46100,P80723,Q6IAA8,Q9BZK7,Q9HCL2,Q9BSK2,Q9P0J0 31 +Aldehyde biosynthetic process 0.3530467312780483 0.1285707126066798 0.8976973418787437 1.0 1.0 4 P60174,P29401 2 +Epithelium development 0.239254939788323 0.1278028455403485 0.8983049981176163 1.0 1.0 179 Q9HCM4,Q96T37,O14641,Q9Y624,Q15382,Q13247,P11047,O60568,P60953,P51153,Q9NWH9,P31749,O75122,Q9Y2Q3,P78536,O43347,P46100,Q9P0M6,P62820 19 +Fertilization 0.2465524095803986 0.1273459407098863 0.8986666008361917 1.0 1.0 35 P16989,P55769 2 +Regulation of multicellular organismal development 0.2043489776924626 0.1272260094029762 0.8987615201235286 1.0 1.0 177 Q13247,Q96T37,Q16706,O75367,Q9Y6I3,Q9P0M6,Q9Y4C8,Q9Y5A9,Q16539,P31749,Q9Y624,O75122,Q9UGM6,P62805,Q15382 15 +Positive regulation of protein containing complex assembly 0.1955883167748699 0.1272250765077475 0.8987622584664483 1.0 1.0 55 P62330,Q9NWH9,Q9H6R0,P35080 4 +Positive regulation of cell substrate adhesion 0.2630877389268173 0.1271408808626577 0.8988288957404655 1.0 1.0 26 Q9HCM4,Q07021,Q9Y2S7,O15144,P60953,P46939 6 +Biological adhesion 0.2249433902623083 0.1269547109383483 0.8989762438534761 1.0 1.0 176 Q9HCM4,P11047,Q9Y2S7,Q9Y5A9,P10586,P62330,P35613,Q16539,P62820,Q13740,P31749,Q9Y624,P60953,Q9HCL2,O75122,P41440,P78536 17 +Phosphatidylinositol biosynthetic process 0.264388601768072 0.1269407637380299 0.8989872827996104 1.0 1.0 24 Q969N2,O60762,Q96S52,Q9UBF8,P78356,Q9NX62,Q9NTJ5 7 +Chromatin organization 0.283146088372701 0.1268744135704131 0.8990397979741231 1.0 1.0 172 Q96T37,O75367,Q12824,P16403,P16402,Q9GZN1,Q96L73,Q96ST3,Q96T23,Q6PL18,Q5SSJ5,P62805,P10412,Q9H2V7,P46013,O43709,Q92522,Q9NPF5,P07305,P05114,Q7Z7K6,Q9HAF1,P46100,Q9P0M6,P17096,Q969T9,Q9BZK7 27 +Response to estrogen 0.257579374615663 0.1266914385298196 0.8991846222973823 1.0 1.0 13 O15164,Q969T9,O15143 3 +Regulation of cellular response to osmotic stress 0.3517436962816429 0.1263963398017683 0.8994181993325006 1.0 1.0 4 O95202,P16989 2 +Regulation of leukocyte proliferation 0.2646070636309632 0.1263757696265766 0.8994344813967698 1.0 1.0 22 P14174,Q9HCL2,Q9Y6D9 3 +Protein localization to cell periphery 0.2459826841536032 0.1260738424593324 0.8996734729270179 1.0 1.0 97 Q92930,Q9HD47,P62330,Q9BXS4,P35613,P31749,Q9UJY5,Q9Y624,P51153,Q5VZ89,P41440 11 +Regulation of microtubule depolymerization 0.2551928734572687 0.1258659122832095 0.8998380660936203 1.0 1.0 12 Q66K74,O75122,Q92974,Q8WWK9 4 +Intracellular mrna localization 0.602954476936983 0.1257983415319093 0.8998915546109456 1.0 1.0 2 Q9H2U1 1 +Response to cytokine 0.2066931144318962 0.1247264716783468 0.9007400996753904 1.0 1.0 168 Q96T37,P42574,Q8N5M9,Q8TCS8,Q8TCT8,Q9Y5A9,Q07820,P60953,Q8WU90,P17655,Q16539,P31749,P16989,O43324,Q02952,P78536,Q86Y07,O15382,P49406,P34896,Q8NFH5,Q9P0J0 22 +Regulation of myeloid leukocyte mediated immunity 0.2522748237085632 0.1245639957006476 0.9008687336017962 1.0 1.0 11 P51809,Q9NRA0,Q9NR30,Q9NY93 4 +Positive regulation of kinase activity 0.2226829262733956 0.1245228753971392 0.9009012893879792 1.0 1.0 78 Q9NWH9,O14641,P31749,O60934,P60953,P14174,P46734,P78536,Q9NQS7 9 +Response to leucine 0.322513317512183 0.1244920415280896 0.9009257013027648 1.0 1.0 5 Q8N122 1 +Recombinational repair 0.2013837962414696 0.1242280073671487 0.9011347473248176 1.0 1.0 61 P09874,A6NHR9,P33992,Q9UBU8,P39748,O60934,Q7Z3K3,Q68E01,O00487,Q9NPF5,Q96SB8,Q9BUR4,P61160,O60216,Q9HAF1,Q8TAF3,P46100,P54132,Q6NSI4,P18887 20 +Secretion 0.2372420588485636 0.1242265082974035 0.9011359342157036 1.0 1.0 166 Q92930,P55809,P35080,Q92614,Q7Z6M1,O15439,P62330,Q9BRT2,Q9Y2D4,P82094,P62820,Q9BRK5,Q8NE86,P20339,O75122,P51153,Q8N5M9,P14174 18 +Non membrane bounded organelle assembly 0.2135588914869823 0.124174602940157 0.9011770305022422 1.0 1.0 166 Q14137,P83731,Q02878,O43633,P37198,P62750,P62841,P61586,P62857,P39019,Q567V2,P82912,Q9Y3A5,P31483,Q9NYY8,Q07021,Q9NQ55,Q9Y5A9,P46087,Q9UN86,O75616,Q8TDN6,Q7Z478,Q9NZM5,P63173,Q9Y2S7,Q9BY44,O75122,Q9Y2R9,Q9H7B2,Q9NQS7,P39023,Q9Y281,O75083,P28289,Q99700,P50748,Q9NUL7,Q14534 39 +Regulation of autophagy of mitochondrion 0.258793307971643 0.1241533670653584 0.901193844172456 1.0 1.0 15 P05141,P42858 2 +Regulation of mrna metabolic process 0.2468400219711544 0.1240296270564091 0.9012918171752802 1.0 1.0 165 Q9NYY8,Q96T37,Q13247,Q7L8L6,O75175,Q13868,Q8TCS8,Q13148,Q9NWH9,Q9Y5A9,Q16539,Q969Z0,P31749,P16989,Q6P6C2,Q9BTD8,P09012,P31483 18 +Positive regulation of mrna splicing via spliceosome 0.2598101929372995 0.1238975308054863 0.9013964080170184 1.0 1.0 16 Q13573,Q15427,Q13595,P08621,Q9UMS4,P30041 6 +Defense response to other organism 0.1950915599738174 0.1236135699583828 0.9016212476244784 1.0 1.0 164 P81605,Q9NZM5,Q9Y5A9,Q3LXA3,P82094,P62820,Q9NX58,Q9HCL2,P60953,Q8N5M9,Q9NUD5,P14174 12 +Anatomical structure formation involved in morphogenesis 0.2618936025741397 0.1235914451217141 0.9016387663557356 1.0 1.0 162 Q9HCM4,Q96T37,O75367,O14641,Q9UGM6,P41440,O75340,Q9Y6I3,O95140,P60953,Q96C57,O75175,P17655,Q16539,P82094,P31749,O75122,Q9H9Y6,P78536,Q9Y281,Q6DKI1,P35613,P28289,Q9H488,Q9UII2 25 +Translational initiation 0.2142809948699931 0.1231612774986572 0.9019793881419094 1.0 1.0 72 Q9UI10,Q9Y5A9 2 +Regulation of cellular response to stress 0.1853671053388063 0.1227795004872174 0.9022817076650078 1.0 1.0 161 Q8TCS8,Q9BRJ7,Q9NWH9,P10586,Q07820,P04179,Q15554,P31749,Q96QC0,P16989,P60953,O43324,Q9HAF1,P55145,Q9NPF5,P14174,Q8TAF3 17 +Protein acetylation 0.1963945815578994 0.1226518019745089 0.9023828320402584 1.0 1.0 58 Q49A26,Q12824,Q00403,Q969T9,Q96ST3,Q9HAF1,Q9H0A0,Q9GZZ1,Q9NPF5,Q5VZE5 10 +Multi organism reproductive process 0.2442199469789325 0.1224113490814776 0.9025732508390952 1.0 1.0 159 P55769,P41440,O94901,Q9Y6I3,Q9Y5A9,Q9H2V7,Q01085,Q9BTX1,Q13162,P17655,O95394,P82094,P31749,P16989,Q9H9Y6,Q8TAF3,P46100,P47914,P35613,Q6P6C2 20 +Positive regulation of mitotic cell cycle 0.2002843035310293 0.1223223114412712 0.9026437627066984 1.0 1.0 46 P35241,Q9Y2S7,Q8N122,Q7LG56,P51608,P31749,Q96QC0,Q96ST3,P78536 9 +Regulation of dna metabolic process 0.272773969324393 0.121827301477332 0.903035791543223 1.0 1.0 143 P16403,P16402,Q9BRJ7,Q86V81,Q15554,Q9ULV3,P10412,O60934,Q92522,Q9NPF5,P07305,P31749,Q9HAF1,Q8TAF3,P46100,P54132,Q96BK5,P0CG13,Q5RKV6,Q96QC0 20 +Protein heterooligomerization 0.2804506800945394 0.1217552713901757 0.903092838572194 1.0 1.0 8 Q9Y285,O43809 2 +Negative regulation of extrinsic apoptotic signaling pathway 0.2611434213284349 0.1217181621344244 0.9031222288858582 1.0 1.0 22 P31749,P42858 2 +Regulation of dna binding 0.2590312298034896 0.121682755405296 0.9031502709321452 1.0 1.0 26 P15531,Q00403,Q96BK5,P09874,Q96L73,Q96ST3,Q96T23,P07305 8 +Positive regulation of dna metabolic process 0.2344704797334636 0.1215154132267027 0.90328280717875 1.0 1.0 91 P46100,P0CG13,Q15554,P31749,Q96QC0,O60934,Q9ULV3,Q9NPF5,Q8TAF3,Q9HAF1 10 +Negative regulation of vascular permeability 0.3485286793568284 0.1211419729456884 0.9035785843637092 1.0 1.0 4 Q02952 1 +Export from cell 0.2520987959525889 0.1208684641819021 0.9037952209381256 1.0 1.0 152 Q92930,P55809,P35080,Q92614,Q7Z6M1,O15439,P62330,Q9BRT2,Q9Y2D4,P82094,P62820,Q9BRK5,Q8NE86,P20339,O75122,P51153,Q8N5M9,P14174 18 +Potassium ion transport 0.2603374834044828 0.1206763379283955 0.9039474016008608 1.0 1.0 22 Q99653,Q96ER9,Q99996,P54709 4 +Positive regulation of organelle organization 0.1992653726738965 0.1205624415709276 0.9040376190644608 1.0 1.0 153 O75367,Q15554,Q96ST3,P30405,Q99996,Q96A26,O15144,Q8NE86,O60934,P60953,P42858,P35080,Q9NWH9,P78356,Q9Y281,P46100,P62330,Q96QC0,Q9NX47,Q9Y613,Q9UII2 21 +Immune system development 0.1967136893744413 0.1205610953743445 0.9040386853960618 1.0 1.0 153 Q96T37,P05141,P09874,P42574,P61586,Q96ST3,Q9NX58,P39019,Q8N5M9,P62805,Q6FI81,Q9Y3A5,A0AV96,O96005,Q9Y5A9,Q9Y520,O60934,P60953,O43809,Q04760,Q13492,O95394,Q07812,Q16539,O00625,P78536,O75083,Q5RKV6,Q8WYA6,P04179,Q9UII2,Q9Y6D9 32 +Hypotonic response 0.3905307599517549 0.1205332831906904 0.9040607156573328 1.0 1.0 3 P30536,Q9Y376 2 +Cellular hypotonic response 0.3905307599517549 0.1205332831906904 0.9040607156573328 1.0 1.0 3 P30536,Q9Y376 2 +Embryonic hindlimb morphogenesis 0.3905307599517524 0.1205332831906868 0.9040607156573356 1.0 1.0 3 P35222,Q15648 2 +Hindlimb morphogenesis 0.3905307599517524 0.1205332831906868 0.9040607156573356 1.0 1.0 3 P35222,Q15648 2 +Microtubule polymerization 0.2505745401902079 0.1200621807256745 0.9044338910326448 1.0 1.0 31 Q9NWH9,Q99996,O75122,Q9HD47 4 +Embryo development ending in birth or egg hatching 0.2635518025346565 0.1198380383345144 0.9046114488265926 1.0 1.0 139 Q9HCM4,Q13503,Q12824,P42574,O14641,Q15554,Q7Z6E9,Q96ST3,Q9Y3Y2,O75787,O75340,Q9Y6I3,O95140,O60934,O60568,Q16706,O75175,P17655,P31749,P16989,Q9H9Y6,Q6DKI1,O43819,Q9BZK7,Q9H488 25 +Intrinsic apoptotic signaling pathway in response to hypoxia 0.3899276236429476 0.1196485852694883 0.9047615306645054 1.0 1.0 3 Q9Y4L1,P06733 2 +Tor signaling 0.2563301599242359 0.1195597834474926 0.9048318792892304 1.0 1.0 27 Q15382 1 +Regulation of systemic arterial blood pressure by hormone 0.3896314697643952 0.1192159328829189 0.9051042840550648 1.0 1.0 3 O75787 1 +Male gamete generation 0.2209015694375072 0.1191470940498791 0.9051588207921756 1.0 1.0 81 P46100,Q13162,Q9Y5A9,O95394,P82094,P16989,Q6P6C2,Q9BTX1,Q8TAF3,O94901 10 +Nuclear transport 0.2462249553463716 0.1190171536970927 0.9052617656919036 1.0 1.0 145 Q9NW64,Q9NVU7,O75152,Q9HD47,Q99653,Q9ULX6,Q13148,Q86V81,P62841,Q16539,P31749,Q96QC0,Q8NFH5,Q9Y3Y2,Q6P6C2,Q8NI27,Q9NPF5,Q86W42 18 +Cell morphogenesis involved in differentiation 0.2588421982329582 0.1188986208047264 0.9053556744499768 1.0 1.0 127 Q8N8S7,Q9HCM4,P11047,Q9Y5A9,Q9NWH9,P35613,P62820,Q13740,O60568,O75962,P41440 11 +Regulation of establishment of protein localization 0.2133140006184921 0.1186587422779624 0.9055457244345236 1.0 1.0 146 Q9NW64,Q9HCM4,P55809,Q92614,Q99653,Q9UMY4,P62330,Q9BRT2,Q8NE86,P60953,Q8N5M9,Q9NPF5 12 +Regulation of chromatin assembly 0.251558645207268 0.1184556346453404 0.9057066459541953 1.0 1.0 13 O75367 1 +Histone modification 0.2434115929588123 0.1184381278715368 0.9057205166957288 1.0 1.0 143 O75367,Q12824,P16403,P22087,P16402,Q96L73,Q96ST3,Q9Y3Y2,Q9GZZ1,Q15022,P10412,Q00403,Q9ULX6,Q13610,Q9NRA0,Q9UBU8,P51608,Q9BWJ5,Q9NPF5,Q13330,Q14839,Q15291,Q6UXN9,Q92541,Q9HAF1,Q86Y07,Q9ULM3,Q9NQS7,P46100,Q969T9,Q9BZK7,Q49A26,Q99986 33 +Response to catecholamine 0.2544848203929035 0.1184176959447977 0.9057367050931304 1.0 1.0 15 P17612,Q92769,P29992,Q96ST3,Q96QK1 5 +Regulation of mrna splicing via spliceosome 0.2051844683737261 0.118353999664123 0.9057871724745664 1.0 1.0 68 Q13247,Q96T37,Q07021,P08621,Q13595,Q92879,Q15637,Q9BTD8,P31483 9 +Rna catabolic process 0.2218913459655042 0.1181745166632601 0.9059293812076228 1.0 1.0 144 Q9NYY8,Q7L8L6,O75175,Q9Y6V7,Q8TCS8,Q13868,Q13148,Q9BRJ7,Q9Y5A9,Q16539,Q969Z0,P31749,P16989,Q12972,Q6P6C2,Q9UKZ1,P62312 17 +Regulation of sodium ion transmembrane transport 0.2563845947591847 0.1180867344924451 0.9059989342484468 1.0 1.0 17 Q99653,P54709,Q9UHD1,Q9HD47 4 +Regulation of smooth muscle cell differentiation 0.3058258146102844 0.1178201163405924 0.9062101900293418 1.0 1.0 6 P04179 1 +Apoptotic signaling pathway 0.1902518845037329 0.1177862731696271 0.906237006253569 1.0 1.0 143 P05141,Q8N2F6,P42574,P30405,O75340,P31689,Q07820,Q96A26,O60934,P62081,P42858,Q8IXB1,Q07812,Q9H0S4,P31749,P16989,O43324,P14174,Q7LG56,P04179,Q969S3,Q9BVC6,Q9P0J0,Q9UII2 24 +Golgi vesicle transport 0.2492864835549599 0.1175088892023107 0.906456800282891 1.0 1.0 136 Q92930,O75695,O75340,O60826,Q92614,Q9HD47,Q9UMY4,Q96JB2,Q9H9E3,Q9UHY1,Q9Y2D4,Q9UJY5,P61019,O14828,P42858,P51153,Q9BZG1,P62820 18 +Cellular component morphogenesis 0.2039160939245358 0.1172561173058045 0.9066570983927154 1.0 1.0 141 Q8N8S7,P11047,Q9Y2S7,P35613,O14641,P82094,Q13740,P60953,O75962,P41440 10 +Cellular response to chemical stress 0.2196424898817634 0.1171298563859351 0.9067571505984438 1.0 1.0 82 Q99720,Q8TCS8,P42574,Q9NWH9,Q07820,P04179,P31749,P16989,Q969S3,P30405,Q86Y07 11 +Leukocyte cell cell adhesion 0.2293950120944891 0.1168515701677103 0.9069776765488085 1.0 1.0 38 Q5JRA6,P42574,Q06124,Q08722,P61586,Q9Y624,P31749,Q9HCL2,P04439,Q9Y6D9 10 +Cellular amino acid metabolic process 0.247551724608423 0.1165696367328143 0.9072011000230328 1.0 1.0 117 A1L0T0,P00505,P38117,Q9UGM6,P30038,P26440,P51608,Q9Y285,O60568,Q9NP81,Q92947,Q5T160,Q9BW92,P52758,P09622,Q15031,Q8TD30,P78330,P25325,P36957,P22033,O15382,Q5ST30,Q96RQ3,P34896,O60725 26 +Negative regulation of ubiquitin protein transferase activity 0.2482819162576109 0.1165119009936903 0.9072468547061248 1.0 1.0 12 P60866,P62841 2 +Homotypic cell cell adhesion 0.255668443788191 0.1162336560543751 0.9074673638438208 1.0 1.0 18 P35241,Q14126,Q9Y624,P15924,P14923 5 +Positive regulation of cell development 0.189893863246797 0.1161063953151202 0.9075682203681852 1.0 1.0 57 Q16706,Q9Y624,P60953,Q15382 4 +Mrna catabolic process 0.246242107929326 0.1160493134217452 0.9076134593242592 1.0 1.0 118 Q9NYY8,Q7L8L6,O75175,Q8TCS8,Q13868,Q13148,Q9BRJ7,Q9Y5A9,Q16539,Q969Z0,P31749,P16989,Q6P6C2,Q9UKZ1,P62312 15 +Dna recombination 0.2381519380465626 0.1159656834156293 0.907679738924273 1.0 1.0 104 P10412,Q92522,P46100,P54132,P16403,Q5RKV6,Q86V81,Q15554,O60934,Q9HAF1,Q8TAF3,Q9NPF5,Q96SB8,P07305 14 +Dna conformation change 0.2128088094533909 0.1159512523922367 0.9076911760619966 1.0 1.0 136 O75367,P16403,P16402,Q96ST3,Q96T23,Q5SSJ5,P62805,P10412,Q9ULX6,O60934,Q92522,P07305,Q2NKX8,P13984,Q7Z7K6,P46100,P54132,Q9P0M6,P0CG13,P17096 20 +Dna replication 0.2387064194258577 0.1150392757569489 0.908413991130349 1.0 1.0 127 Q86V81,Q9NY93,Q15554,Q7Z6E9,Q96ST3,Q9ULV3,Q7L590,P41440,Q8NFC6,Q8WTT2,O60934,P60953,Q9Y2S7,Q9HAF1,Q9BZE4,P35251,P46100,P54132,P0CG13,P17096 20 +C21 steroid hormone biosynthetic process 0.5939101597829327 0.1149756561260999 0.908464417657675 1.0 1.0 2 P30536 1 +Regulation of supramolecular fiber organization 0.2402624430095418 0.1149071867392831 0.9085186886362532 1.0 1.0 112 Q8NBJ5,Q9UHB6,Q9Y281,P35080,P53365,Q9HD47,P62330,Q9NWH9,Q8WWK9,O15144,Q9Y624,O75122,P60953,O15020,Q9Y613 15 +Regulation of metal ion transport 0.1911253213202936 0.1148150222265235 0.9085917417872944 1.0 1.0 59 Q9HD47,Q99653,Q9UHD1,Q99996,Q09666,Q07812,P61586,P31749,P54709,P46939,P42858 11 +Regulation of peptidyl threonine phosphorylation 0.2760495318634864 0.1146612004341522 0.9087136686000457 1.0 1.0 8 Q04637,Q8N122,P61086,Q9Y376,Q9C0C2,P53350,P28482 7 +Endocytosis 0.2321760624599219 0.114636138909231 0.9087335338165308 1.0 1.0 128 Q92614,Q9Y6I3,Q7Z6M1,Q9UMY4,P62330,Q9UBF8,P62820,P53680,P60953,Q9UBG0,P41440 11 +Regulation of digestive system process 0.5936086825444612 0.1146276057563191 0.9087402977008856 1.0 1.0 2 Q9H4A3 1 +Pore complex assembly 0.2445586457073834 0.1142737648046759 0.9090207788969622 1.0 1.0 11 Q92621,Q8N1F7,Q9NQC3,P12270,P57740,P49790,P55196,P49368,P50990,Q9BTX1 10 +Negative regulation of intracellular protein transport 0.2424078667629716 0.1142573843459986 0.9090337635667808 1.0 1.0 10 Q99653 1 +Regulation of ion transmembrane transport 0.1960410277196559 0.113888200901071 0.909326419023653 1.0 1.0 64 O75083,Q9HD47,Q99653,Q9UHD1,Q9BSH4,Q99996,Q09666,Q07812,P54709,P46939,P42858,Q9BVC6,P30405 13 +Golgi to plasma membrane transport 0.2488665500409666 0.1138844682933843 0.9093293779624804 1.0 1.0 29 Q9BZG1,Q9UJY5,O60826,Q9Y2D4 4 +Positive regulation of ion transmembrane transport 0.2471943285563924 0.1138550871321517 0.9093526692456748 1.0 1.0 30 Q99653,Q9UHD1,Q99996,P54709,P42858 5 +Protein localization to nucleus 0.2008784431680522 0.113435948607352 0.9096849407642332 1.0 1.0 127 Q9NW64,P09874,P37198,Q68CQ4,Q96ST3,Q9ULV3,Q5JTV8,Q9UI26,O94901,Q99653,Q9NZM5,Q5SRE5,Q9NPF5,O60832,Q9HD47,Q9UHD1,Q13148,Q16539,P31749,Q9H7B2,Q96BK5,Q96QC0,Q8NFH5,Q9H8V3,Q13895,Q9UH99 26 +Positive regulation of developmental growth 0.2498213755733701 0.113335809742859 0.909764328058672 1.0 1.0 28 P31749,Q9HCL2,Q16539 3 +Nuclear pore complex assembly 0.275178183705936 0.1133034282901067 0.9097899993626736 1.0 1.0 8 Q9BTX1 1 +Arginine catabolic process 0.5924027735905864 0.1132435469707171 0.9098374722046144 1.0 1.0 2 P16930 1 +Dna biosynthetic process 0.2051109628439387 0.1131583134769781 0.9099050443533594 1.0 1.0 73 Q9Y2S7,Q96BK5,P0CG13,Q15554,Q9HAF1,Q9H0A0,P41440,O60832 8 +Negative regulation of organelle organization 0.2328514414234516 0.1131175771201145 0.9099373399060352 1.0 1.0 117 Q9UHB6,P46100,P35080,Q96BK5,Q9NWH9,Q15554,Q8WWK9,P31749,Q9Y624,O75122,O60934,O15020,P28289,Q9H0A0,P50748,P30405,Q9Y6D9 17 +Endochondral bone morphogenesis 0.3157442656305917 0.1128950477483471 0.910113762555354 1.0 1.0 5 Q9NX62 1 +Regulation of monocyte chemotaxis 0.385118237531259 0.1127651769573223 0.9102167269628828 1.0 1.0 3 O94813 1 +Cell part morphogenesis 0.2120209121863487 0.1125888413361092 0.910356532118792 1.0 1.0 123 Q8N8S7,P11047,P35613,O14641,Q13740,P60953,O75962,P41440 8 +Histone h4 acetylation 0.2529680624681668 0.1118599641105206 0.9109344413230128 1.0 1.0 22 Q9GZZ1,Q9NPF5,Q12824,Q9HAF1 4 +Developmental growth 0.2250452751084287 0.1117045339984856 0.9110576842225552 1.0 1.0 114 Q9HCM4,Q13308,P11047,P46100,Q15056,Q16539,Q7Z6E9,P31749,Q13740,Q9BZK7,P16989,O15020,Q9HCL2,O60934,Q96ST3,Q05086,Q8TAF3 17 +Striated muscle contraction 0.2527893170914276 0.1116070904494684 0.9111349497858938 1.0 1.0 21 P17612,Q9HD47,Q99996,P15924,Q14126,P46734,P14923,P16615 8 +Spliceosomal snrnp assembly 0.2504290222360967 0.111483873741235 0.9112326527707796 1.0 1.0 26 Q9Y312,P09234,Q6P2Q9,O94906,P62318,O95400,Q9UMS4,P62314,P57678 9 +Positive regulation of immune system process 0.1944527442917634 0.111241330115924 0.9114249783041788 1.0 1.0 119 Q92614,Q9H2U1,Q9NY93,Q9UI10,P61586,P51809,Q15233,Q96ST3,P39019,Q15046,Q9UJZ1,Q07021,Q06124,Q9NRA0,Q8NE86,Q9NUD5,Q9NR30,Q07812,P31749,P04439,Q9BY67,P14174,P78536,Q9UKG1,Q5JRA6,Q5RKV6,Q9HCL2 27 +Response to dopamine 0.247201210287438 0.1111760245630879 0.9114767633817852 1.0 1.0 14 P49840,Q92769,P08754,P29992,P21333,Q96ST3,P27361,Q96QK1,O14745,P50570,P28482,P49841,Q92542 13 +Cellular glucose homeostasis 0.2443955588903857 0.1108208299143155 0.9117584272102972 1.0 1.0 30 P55809,Q12824,Q15120,O95563,Q96ST3,P17480,Q8N5M9,P52789,P08069 9 +Negative regulation of cellular macromolecule biosynthetic process 0.2006205574751656 0.1108166680330656 0.911761727583142 1.0 1.0 117 P54132,Q13868,Q96BK5,Q9Y5A9,P34896,Q9BXS4,Q15554,Q9UKZ1,P31483 9 +Sulfur compound metabolic process 0.2220680965052498 0.1106986185659977 0.9118553414729696 1.0 1.0 101 Q16775,Q96I99,Q8TB36,P10515,Q02218,O95563,P08559,Q92947,Q5T440,Q9UMS0,Q8TB61,Q4G176,Q04760,Q15120,O15217,Q9Y2Q3,Q03426,P25325,P36957,P22033,Q96RQ3,Q8WVX9,O60725,P04179,Q96IU4,Q9HCL2,Q9NZL9,Q9NX62,Q9P2R7 29 +Negative regulation of histone modification 0.2513025375627978 0.1105048831313682 0.9120089774104728 1.0 1.0 19 O75367,Q12824 2 +Cell morphogenesis involved in neuron differentiation 0.217754650954827 0.1104775109421959 0.9120306843499116 1.0 1.0 93 Q8N8S7,P11047,P35613,Q13740,O75962,P41440 6 +Cell redox homeostasis 0.2463668503368155 0.1102132039470324 0.9122402908331692 1.0 1.0 14 P30048,Q13162,P09622,Q96HE7 4 +Inorganic ion transmembrane transport 0.2063627532114986 0.1098107822263907 0.9125594397814896 1.0 1.0 112 P05141,P21283,P56134,Q00325,P48047,Q09666,Q96ER9,P30405,Q9UJZ1,Q9UDW1,Q99653,Q99996,Q8NE86,P42858,O14548,P20674,Q9HD47,Q9UHD1,Q9BSH4,Q07812,P03915,P54709,P08195 23 +Positive regulation of transferase activity 0.1747812309688839 0.1094902632708855 0.912813644124268 1.0 1.0 113 P0CG13,Q9NWH9,O14641,P31749,O60934,P60953,P14174,P46734,P78536,Q9NQS7 10 +Positive regulation of cellular respiration 0.382689987937285 0.109404827287818 0.9128814051117806 1.0 1.0 3 P55072,Q9H1K1 2 +Negative regulation of protein export from nucleus 0.3826899879372806 0.1094048272878121 0.9128814051117852 1.0 1.0 3 P46060,Q00535 2 +Negative regulation of protein sumoylation 0.3826899879372792 0.1094048272878102 0.9128814051117868 1.0 1.0 3 Q9NVN8,P35222 2 +Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.3826899879372742 0.1094048272878035 0.9128814051117922 1.0 1.0 3 Q9NWS0,Q9NVX2 2 +Peptidyl lysine modification 0.2160232161288613 0.1093205450494262 0.91294825166191 1.0 1.0 102 P10412,O75367,P46100,Q12824,P16403,P16402,Q13610,Q969T9,Q96L73,O60568,Q9HAF1,Q49A26,Q9NPF5 13 +Radial glial cell differentiation 0.340830379182201 0.1091971005631117 0.9130461599743152 1.0 1.0 4 P61586 1 +Negative regulation of mrna processing 0.2504244173654231 0.109104214992881 0.9131198317690256 1.0 1.0 22 Q13247,Q9BTD8 2 +Gamete generation 0.2058431646682188 0.1089415181215499 0.9132488758989 1.0 1.0 108 P46100,Q13162,Q9Y5A9,O95394,Q9H2V7,P82094,P31749,P16989,Q6P6C2,Q01085,Q9BTX1,Q8TAF3,O94901 13 +Protein import 0.2107403164081601 0.1087590522826892 0.9133936026406616 1.0 1.0 89 Q92930,Q9NW64,Q9NS69,Q9HD47,Q99653,Q16539,P31749,Q96QC0,Q8NFH5,Q9NPF5 10 +Interleukin 2 production 0.2721232256115989 0.108663966714754 0.9134690229619749 1.0 1.0 8 P23396,P04083,P00491,Q01082,Q92990,P15311,Q9UJZ1 7 +Positive regulation of establishment of protein localization 0.2125495402191183 0.1085584659988962 0.9135527053206708 1.0 1.0 99 Q9NW64,O00159,P55809,Q92614,Q13148,Q99653,P62330,Q16539,O95563,Q8NE86,P60953,Q9NPF5,Q9BZL1,O60832 14 +Regulation of mrna processing 0.2111115021334632 0.1085573558699393 0.9135535858715428 1.0 1.0 91 Q13247,Q96T37,Q07021,Q14151,P08621,O43809,Q9NWH9,Q13595,Q15637,Q9BTD8,P09012,P31483 12 +Regulation of protein containing complex assembly 0.1814896107583012 0.1084511659294363 0.9136378158959166 1.0 1.0 109 P35080,P62330,Q9NWH9,P60953,O15020,Q9NZM5,Q9H6R0 7 +Regulation of neuroblast proliferation 0.3396681749622944 0.1074714091679926 0.9144150061100708 1.0 1.0 4 P04637,P35222,O60341 3 +Cellular carbohydrate biosynthetic process 0.2485761427845594 0.1072355537574351 0.914602110222 1.0 1.0 20 P31749,P62140 2 +Regulation of ion transport 0.2045595850568223 0.1072000106201665 0.914630307005581 1.0 1.0 86 O75083,Q9HD47,Q9UHD1,Q99653,Q9BSH4,Q99996,Q07812,Q09666,P31749,P61586,P51809,P46939,P42858,P54709,Q9BVC6,P30405,P14174 17 +Regulation of apoptotic signaling pathway 0.2012145071864104 0.1068185979467656 0.9149328928640988 1.0 1.0 98 P05141,Q8N2F6,P31689,Q7LG56,Q07812,Q07820,P04179,P31749,P16989,P62081,P42858,O43324,P30405,P14174,Q9P0J0 15 +Regeneration 0.2316559290369329 0.1067742305634353 0.9149680916116144 1.0 1.0 34 P11047 1 +Mitochondrion localization 0.2478486590748019 0.1064899977536032 0.9151935909207908 1.0 1.0 20 Q9NVT9 1 +Regulation of rna splicing 0.2002145107581432 0.1060327798152291 0.9155563442479656 1.0 1.0 92 Q9NW64,Q96T37,Q8IXT5,P24928,Q09666,Q9UKA9,Q9UMS4,P31483,Q13247,Q07021,P62277,P08621,Q13595,Q92879,Q9BTD8,Q14684,Q8IY67,Q15427,Q15637 19 +Regulation of chromosome organization 0.1818095775334494 0.1056357204549219 0.9158713824753706 1.0 1.0 98 Q9H0A0,O75367,P46100,Q96BK5,Q15554,Q96QC0,O60934,Q96ST3,Q7Z7K6,P50748,Q9Y6D9 11 +Blastocyst growth 0.2347125456325052 0.1051857676695265 0.9162284038248474 1.0 1.0 10 O60934,Q9Y3A5 2 +Positive regulation of cell cycle 0.1863396724014514 0.1051273931024532 0.916274723183802 1.0 1.0 95 O75367,P37198,P61586,Q96ST3,P43487,P51608,P60953,P08069,P35241,Q9Y2S7,P31749,O60216,Q7Z7K6,P78536,P46100,Q8N122,Q7LG56,Q96DE0,Q96QC0,Q9H8V3,P62244,Q9Y6D9 22 +Regulation of protein localization to cell periphery 0.2104287165094835 0.1048268289043115 0.9165132209431736 1.0 1.0 40 P31749,P62330,Q9BXS4 3 +Dna methylation or demethylation 0.2445111853129941 0.1046459477508383 0.9166567538027304 1.0 1.0 25 Q9NPF5 1 +Regulation of dendritic spine development 0.2396439451375103 0.1044852929386104 0.9167842389290732 1.0 1.0 13 Q05086,P62330,P61160,Q9H2U1 4 +Regulation of transmembrane transport 0.192500452269146 0.1044445393106587 0.91681657867679 1.0 1.0 79 Q9HD47,Q99653,Q9BSH4,Q16539,Q09666,P31749,P54709,P42858,Q9BVC6,P30405 10 +Positive regulation of protein kinase b signaling 0.245214647745523 0.1041646101848347 0.9170387181341696 1.0 1.0 19 Q86UE4,Q07021,Q9NWH9,P08069 4 +Inner ear receptor cell stereocilium organization 0.3092939046469473 0.1025767602044975 0.9182988881961582 1.0 1.0 5 Q9BW83,Q14160,Q14651,Q13099 4 +Monosaccharide metabolic process 0.1825060630412414 0.1023279007454971 0.9184964099491932 1.0 1.0 72 Q16706,P62140,P10515,Q96C23,Q16539,P11498,P31749,P08559,Q9H488 9 +Melanocyte differentiation 0.5824540247211253 0.1023180753077667 0.9185042085813976 1.0 1.0 2 P29992 1 +Organ growth 0.2414397924699223 0.1018703923617417 0.9188595511460012 1.0 1.0 25 P31749,P16989,Q05086,Q16539 4 +Positive regulation of protein dephosphorylation 0.2394682002453553 0.1015709871077052 0.9190972092527664 1.0 1.0 15 Q15435 1 +Positive regulation of transporter activity 0.2405872292692509 0.1011345863739702 0.9194436228334426 1.0 1.0 25 Q99653,P54709,P42858 3 +Dna geometric change 0.1685036460464478 0.1007124404107448 0.919778735569541 1.0 1.0 56 P46100,P54132,P0CG13,Q2NKX8,P13984,O60934 6 +Regulation of glucose metabolic process 0.2407971700795643 0.1006847266985975 0.919800736084472 1.0 1.0 24 P31749,Q15120,P62140 3 +Rna stabilization 0.2364810354260577 0.1005538145880532 0.919904661420032 1.0 1.0 28 P16989,Q16539,Q13148 3 +Aspartate family amino acid catabolic process 0.2817751839828513 0.1005145763313178 0.9199358112034728 1.0 1.0 7 P36957,P00505 2 +Regulation of amino acid transport 0.3074834037416947 0.099808092658417 0.9204966831231718 1.0 1.0 5 Q15041,P55011,P05556,Q15042 4 +Amine transport 0.3074834037416947 0.099808092658417 0.9204966831231718 1.0 1.0 5 Q15041,P55011,P05556,Q15042 4 +Midbrain development 0.2396715119384749 0.0990473265026243 0.9211006937029548 1.0 1.0 19 Q16352,P80723,P61586,P60953,P35222,P24539,O75489,O14949 8 +Organelle membrane fusion 0.2269729418821972 0.0989396757394445 0.9211861667514084 1.0 1.0 32 Q9NVJ2,Q92930,O75396,Q86Y82,P78356,P51153,Q9BZG1 7 +Protein localization to nuclear body 0.2322346537647402 0.0987184546779573 0.921361815724624 1.0 1.0 12 Q99832,P50991,Q9BUR4,P48643,P40227,P78371,Q4G0J3,P17987,P49368,P50990,O60832 11 +Leukocyte differentiation 0.1620032914872737 0.0978746879815303 0.9220317995295622 1.0 1.0 61 P05141,P09874,O96005,Q04760,Q16539,Q07812,O00625,P60953,Q8N5M9,P78536 10 +Chemosensory behavior 0.5779318661441013 0.0976390694010067 0.9222188998142328 1.0 1.0 2 O76024 1 +Olfactory behavior 0.5779318661441013 0.0976390694010067 0.9222188998142328 1.0 1.0 2 O76024 1 +Positive regulation of synapse assembly 0.5779318661440978 0.0976390694010031 0.9222188998142355 1.0 1.0 2 Q9H2P0 1 +Establishment of protein localization to mitochondrial membrane 0.2371773549671488 0.0972665440996398 0.9225147239303771 1.0 1.0 18 Q9NS69,Q9P0J0,Q07812,O60220 4 +Establishment of protein localization to plasma membrane 0.2362374535635321 0.096996554348762 0.9227291307794494 1.0 1.0 24 O95573,Q9UPN3,P51149,P61006,P61026,Q9UJY5,Q96QK1,Q9BZG1,O75608 9 +Regulation of double strand break repair via homologous recombination 0.2332129752951372 0.0969818557333605 0.9227408035461168 1.0 1.0 27 Q6NSI4,P61160,P09874,Q9UBU8,Q9HAF1,Q9NPF5,A6NHR9,Q8TAF3 8 +Sister chromatid cohesion 0.2317678656520989 0.0969522475208143 0.9227643166791256 1.0 1.0 28 O75367,P46100,Q14807,O43683,P0CG13,P39748,Q7Z3K3,O60216,Q9GZZ1,P35222,Q14683 11 +Golgi to plasma membrane protein transport 0.2358048778836473 0.0966078746300429 0.9230378026996876 1.0 1.0 17 Q9UJY5 1 +Dedifferentiation 0.5767259571902277 0.0964212285374949 0.9231860327390502 1.0 1.0 2 Q14103 1 +Negative regulation of myeloid leukocyte differentiation 0.5767259571902237 0.096421228537491 0.9231860327390532 1.0 1.0 2 P35222 1 +Negative regulation of osteoblast differentiation 0.5767259571902237 0.096421228537491 0.9231860327390532 1.0 1.0 2 Q9H6W3 1 +Regulation of microtubule polymerization or depolymerization 0.2151514499437686 0.0962600043287513 0.9233140754498266 1.0 1.0 35 Q9NWH9,O75122,Q9HD47 3 +Mitochondrial depolarization 0.3049691716630521 0.0960552587031176 0.9234766853136922 1.0 1.0 5 Q9UII2 1 +Tumor necrosis factor superfamily cytokine production 0.2354293038861753 0.095424631089981 0.9239775525643544 1.0 1.0 21 Q06124,Q9NRA0,Q08722,P30046,Q02952,Q92974,P14174 7 +Erythrocyte homeostasis 0.2120788577006909 0.0944769723642258 0.9247302740048462 1.0 1.0 35 P42574,Q16539,P62847,Q9NX58,Q9UII2 5 +Regulation of t cell activation 0.2110611604308457 0.0939253435725922 0.925168461568768 1.0 1.0 35 P42574,O96005,Q06124,P61586,P31749,Q9HCL2,P04439,Q9Y6D9 8 +Regulation of modification of synaptic structure 0.3296482480431801 0.0934280744973686 0.9255634878323088 1.0 1.0 4 P60953 1 +Regulation of modification of postsynaptic structure 0.3296482480431801 0.0934280744973686 0.9255634878323088 1.0 1.0 4 P60953 1 +Positive regulation of peptidyl threonine phosphorylation 0.2759661835748765 0.0920519185593374 0.9266567896147576 1.0 1.0 7 Q8N122,P61086,Q9Y376,Q9C0C2,P53350,P28482 6 +Positive regulation of leukocyte cell cell adhesion 0.2291634951957878 0.0912145876061219 0.9273220840405798 1.0 1.0 22 P31749 1 +Vesicle mediated transport in synapse 0.2050521677395052 0.0910338677085997 0.9274656802326549 1.0 1.0 35 P62330,P35080 2 +Positive regulation of intracellular lipid transport 0.3680741046034077 0.0907856163746191 0.9276629393203556 1.0 1.0 3 Q5SW96 1 +Regulation of intracellular lipid transport 0.3680741046034077 0.0907856163746191 0.9276629393203556 1.0 1.0 3 Q5SW96 1 +Negative regulation of mrna catabolic process 0.224521855071884 0.0905208755752963 0.9278733057410172 1.0 1.0 26 P16989,Q16539 2 +Regulation of microvillus length 0.3676115802171338 0.090240743393534 0.9280959078400132 1.0 1.0 3 P15311,Q6IBS0 2 +Cellular carbohydrate catabolic process 0.2274414675846221 0.0897705895574204 0.9284695199350964 1.0 1.0 19 Q3LXA3 1 +Phenol containing compound catabolic process 0.569490503466979 0.089375176557248 0.9287837507448948 1.0 1.0 2 P16930 1 +Eyelid development in camera type eye 0.3667068757539291 0.0891827067331594 0.9289367086363968 1.0 1.0 3 Q92769,Q13547 2 +Regulation of potassium ion transmembrane transporter activity 0.219029351358142 0.0889302855499872 0.9291373145127744 1.0 1.0 11 P54709 1 +Androgen receptor signaling pathway 0.2258737820359644 0.0888814074935755 0.9291761597344133 1.0 1.0 18 Q05086,Q14151,P82094 3 +Mrna 3 end processing 0.199486037782179 0.0888591791215529 0.9291938255098168 1.0 1.0 35 O43809,Q8TCS8,P09012 3 +Positive regulation of nervous system development 0.1673359103333002 0.0881838617462661 0.9297305438038216 1.0 1.0 41 Q15382 1 +Polyketide metabolic process 0.5679831172746388 0.0879629806614739 0.9299060992034364 1.0 1.0 2 P15121 1 +Aminoglycoside antibiotic metabolic process 0.5679831172746388 0.0879629806614739 0.9299060992034364 1.0 1.0 2 P15121 1 +Tertiary alcohol metabolic process 0.5679831172746388 0.0879629806614739 0.9299060992034364 1.0 1.0 2 P15121 1 +Adp metabolic process 0.2001556918585106 0.0878742470801333 0.929976625258574 1.0 1.0 34 P56537,P18669,P04406,Q02218,P09972,P00558,P60174,P00568,P17858,P51570,P27144,Q9BW91,P52789,Q9UIJ7 14 +Tetrapyrrole metabolic process 0.2243673497727012 0.0878359911969719 0.9300070314648958 1.0 1.0 19 P22830,Q9BUT1,Q5T440,Q9UII2 4 +Regulation of tor signaling 0.2233010316771526 0.0874217346475996 0.9303362937649844 1.0 1.0 21 O75340,Q9Y2Q5,Q6IAA8,Q8N122,Q15382 5 +Negative regulation of cellular response to hypoxia 0.567380162797705 0.0874034282560472 0.9303508444552244 1.0 1.0 2 Q9Y4L1 1 +Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway 0.567380162797705 0.0874034282560472 0.9303508444552244 1.0 1.0 2 Q9Y4L1 1 +Positive regulation of neurogenesis 0.1689969167953028 0.0873786045129918 0.9303705754478432 1.0 1.0 40 Q15382 1 +Response to alkaloid 0.2230693195035559 0.0872917417801115 0.9304396180695969 1.0 1.0 21 P42574,P54132 2 +Water soluble vitamin biosynthetic process 0.3242835595776796 0.0865158823501334 0.9310563311197412 1.0 1.0 4 Q9NVS9,Q9Y617,P14550 3 +Metanephros morphogenesis 0.3639665184892557 0.086040149039568 0.9314345012276444 1.0 1.0 3 P80723 1 +Regulation of double strand break repair 0.1839238479617897 0.0857920735599606 0.9316317076301748 1.0 1.0 36 Q6NSI4,P61160,P09874,Q9BRJ7,Q9UBU8,Q9HAF1,Q9NPF5,A6NHR9,Q8TAF3 9 +Regulation of muscle contraction 0.2203839053499294 0.0856403368557628 0.9317523320587078 1.0 1.0 20 P20020,P17612,Q9HD47,Q99996,P15924,P61586,Q14126,P14923,P16615 9 +Negative regulation of nucleotide metabolic process 0.3230769230769252 0.0850185359419742 0.9322466545112637 1.0 1.0 4 Q9NQ88,P40763,P09874 3 +Succinate metabolic process 0.3230078481875389 0.0849334519078109 0.9323142970862712 1.0 1.0 4 Q9P2R7 1 +Negative regulation of b cell activation 0.3229949475383366 0.0849175689218422 0.9323269242576102 1.0 1.0 4 P42574 1 +Regulation of synapse structure or activity 0.1995634588981464 0.0845672510069155 0.932605435680648 1.0 1.0 31 P62330,P60953 2 +Negative regulation of intracellular steroid hormone receptor signaling pathway 0.214091321439371 0.0844475211085851 0.9327006258102896 1.0 1.0 12 Q92600,P38398,O75376,P27797,Q99623,P61586,A5YKK6,P51532,P35232,Q13547,Q96EB6 11 +Tyrosine catabolic process 0.5640639131745457 0.0843799500387213 0.9327543479788478 1.0 1.0 2 P16930 1 +Rna phosphodiester bond hydrolysis exonucleolytic 0.2129457014769544 0.0842696343644467 0.9328420547700892 1.0 1.0 25 Q9H9L3,Q06265,Q8TCS8,Q13868 4 +Negative regulation of lymphocyte activation 0.216036308623292 0.0842661018073291 0.932844863353172 1.0 1.0 14 Q16512,P04083,P42574,Q96J02,P32119,Q92990,P10644,P51452,Q8WXW3,P09429,O15347,Q14160,Q9Y6D9 13 +Dendritic spine development 0.2123959673345156 0.0834598479522607 0.933485902656549 1.0 1.0 24 P61160,P62330,O96013,P60953,Q05086 5 +Negative regulation of rna catabolic process 0.1795102902379656 0.0831687859797528 0.9337173319073176 1.0 1.0 34 P16989,Q16539,Q13148 3 +Protein quality control for misfolded or incompletely synthesized proteins 0.2120195461152577 0.0831617060171105 0.9337229613984296 1.0 1.0 12 Q9BUN8 1 +Regulation of mrna 3 end processing 0.2129672322048587 0.081773811468296 0.9348265817317688 1.0 1.0 18 P09012 1 +Regulation of response to endoplasmic reticulum stress 0.2074697865119547 0.0806368132165694 0.9357307888060208 1.0 1.0 22 P55145,Q07812,Q04323 3 +Gtp metabolic process 0.2093424721045176 0.0805869480146259 0.9357704464181704 1.0 1.0 14 P61586,Q9UIJ7 2 +Negative regulation of cell size 0.3188409082955827 0.0799266920010217 0.9362955605904392 1.0 1.0 4 P61586 1 +Er nucleus signaling pathway 0.2070918014392829 0.0794873300009041 0.9366450089202648 1.0 1.0 14 Q9UM00,Q9BY44,O94905,O75477,P57088 5 +Regulation of cellular carbohydrate metabolic process 0.1863292032355116 0.0793176758392669 0.9367799473082654 1.0 1.0 28 P31749,Q15120,P62140 3 +Ncrna export from nucleus 0.2807123453063716 0.0780745849992291 0.937768723702251 1.0 1.0 6 O43592,P05455,Q9H6R4,Q09161,P06748 5 +Histone h3 k9 acetylation 0.2651401330606376 0.0779357779032949 0.9378791393005276 1.0 1.0 7 Q12824 1 +Positive regulation of dna biosynthetic process 0.1270903010033453 0.0777847604331369 0.9379992691290366 1.0 1.0 30 P40227,P12004,P40938,P35222,Q9BRT9,P17987,P50991,P48643,P08238,Q9BRX5,P27361,P35250,P50990,O60832,Q99832,Q15185,Q9BUR4,P28482,P35249,O95453,P0CG13,P13010,P09651,P07900,P40937,O15381,Q8WVB6,P49368,P78371 29 +Regulation of membrane depolarization 0.2647710686958339 0.0774915966161399 0.938232476102076 1.0 1.0 7 Q9HD47 1 +Regulation of integrin activation 0.5559240277358958 0.077340885100832 0.9383523666857454 1.0 1.0 2 Q15058 1 +Luteolysis 0.35585859972368 0.0772827058335371 0.938398648502144 1.0 1.0 3 P42574 1 +Smooth muscle cell differentiation 0.2643917178356844 0.07703753175936 0.938593687644412 1.0 1.0 7 P04179 1 +Cellular response to interferon gamma 0.1872341320458773 0.0767204401324897 0.9388459435901616 1.0 1.0 24 O00159,O75369,P04406,P61160,Q9UNK0,O00186,P40429,Q08722,P60953 9 +Glutamine family amino acid metabolic process 0.1459445643363012 0.0765192296197748 0.9390060158013048 1.0 1.0 28 P00505,Q96C36,Q06210,P51608,P32322,P30038 6 +Dendritic spine morphogenesis 0.1989015895202545 0.0759882544417172 0.939428442777134 1.0 1.0 15 Q05086,P60953,P61160 3 +Positive regulation of telomerase activity 0.1977345074011066 0.0755820079585004 0.9397516510827456 1.0 1.0 15 Q15185,Q9BUR4,P35222,O60832 4 +Regulation of lamellipodium organization 0.1948802768797171 0.075017716312792 0.9402006160315676 1.0 1.0 17 O15144,O94813,P60953 3 +Chaperone mediated protein complex assembly 0.1940750435820004 0.0744805037013048 0.940628053866048 1.0 1.0 12 Q15185,P36776,Q9BT73 3 +Multicellular organismal signaling 0.174037718697834 0.0743946332878806 0.9406963789875736 1.0 1.0 23 P20020,P17612,Q9HD47,Q99996,P15924,Q14126,P14923,P16615 8 +Rna interference 0.1912964641885755 0.0739837267617565 0.941023333933518 1.0 1.0 10 Q9H7Z3,Q08211,Q92879,O94992,P55265,Q99598,Q9UPY3,Q15631,Q5KU26 9 +Interleukin 1 production 0.2214501510573961 0.0738146136743133 0.941157898717732 1.0 1.0 9 P19367,P49755,Q92769,P04083,Q99584,P30740,P40763,P04792 8 +Regulation of histone h3 k4 methylation 0.1822500461627939 0.0730776779826421 0.9417443045451692 1.0 1.0 19 O75367,Q13573,Q92541,P61964,P51610,Q9H3P2,Q9NWS0,P35222,P26358 9 +Regulation of postsynapse organization 0.1887079373765935 0.072891979333041 0.9418920765310336 1.0 1.0 15 P61160,Q9H2U1,P19022,Q96HC4,P11142,Q96QK1,Q05086,Q00535 8 +Microtubule depolymerization 0.1844911306107077 0.0725680189315868 0.9421498767931398 1.0 1.0 17 O75122 1 +Dendrite arborization 0.5498944829665281 0.0724689867752003 0.9422286855240988 1.0 1.0 2 Q13641 1 +Telomerase holoenzyme complex assembly 0.3501206272617709 0.0715626265640944 0.942949983465958 1.0 1.0 3 Q15185,P08238 2 +Action potential 0.161755756058667 0.0714849893579386 0.9430117707505656 1.0 1.0 20 P29992,Q9HD47,Q99996,P15924,Q14126,P14923,P16615 7 +Mitotic chromosome condensation 0.1838568542191967 0.0711917010938915 0.943245186226874 1.0 1.0 12 Q9ULX6,O95347 2 +Response to cocaine 0.2403287312346996 0.0709503844810206 0.9434372433638192 1.0 1.0 8 Q05086,Q92769,Q00535 3 +Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.2400876885128155 0.0707331121332021 0.9436101671567972 1.0 1.0 8 Q9ULW3,Q9Y2P8,Q15050 3 +Spinal cord development 0.1796631066089488 0.0701213091212629 0.944097106221101 1.0 1.0 12 Q9ULW3,P25325 2 +Positive regulation of telomere maintenance via telomere lengthening 0.1469344938515629 0.0694514159531287 0.944630303673142 1.0 1.0 18 Q99832,P48643,P40227,O60832,Q9H2U1,O95453,P09651,P13010,P22626,P27361,P17987,P28482,P35222,P50990,P49368,P78371 16 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.1583409022101174 0.0687541716035711 0.9451852974782516 1.0 1.0 16 O00560,Q8N1F7,P08238,Q13573,P09874,P33981,Q9BRX2,Q93062,Q14318,Q14980,P67870,Q9GZN8,P20248,P78536,Q13418 15 +Homocysteine metabolic process 0.3083177208365726 0.068364053932147 0.9454958356655524 1.0 1.0 4 P25325 1 +Interferon gamma production 0.2371252674940769 0.0681399241231956 0.94567424933979 1.0 1.0 8 Q07021,P04439 2 +Negative regulation of jnk cascade 0.2818346409173145 0.0664075366156995 0.9470533700984508 1.0 1.0 5 P31689,P43034,P51452,O75376 4 +Corpus callosum development 0.3443908323281088 0.0662342303727078 0.9471913447020835 1.0 1.0 3 P43034,Q00535 2 +Regulation of dna topoisomerase atp hydrolyzing activity 0.3437876960193073 0.0656951977960176 0.9476204957593372 1.0 1.0 3 Q00839,Q08211 2 +Regulation of isomerase activity 0.3437876960193073 0.0656951977960176 0.9476204957593372 1.0 1.0 3 Q00839,Q08211 2 +Serine transport 0.3046757164404244 0.0647134040087428 0.9484021903385944 1.0 1.0 4 Q96QD8,Q96NB2,Q9H9B4 3 +Positive regulation of necrotic cell death 0.2698460609719317 0.064319202689352 0.9487160635772748 1.0 1.0 6 P30536,P00403,P04637,Q7Z3C6,Q9NZI8 5 +Regulation of chromosome condensation 0.2304439746300223 0.0627989308335199 0.9499266172616594 1.0 1.0 8 Q9UIG0,O60264,Q9NTJ3,Q15021,O95347,Q7Z5K2,Q9BPX3 7 +Translational readthrough 0.5357250527585098 0.0621197837716008 0.9504674422515068 1.0 1.0 2 P57772 1 +Negative regulation of neural precursor cell proliferation 0.3395657418576647 0.0620363224917041 0.950533906528498 1.0 1.0 3 P04637,Q13418 2 +Autophagy of peroxisome 0.338980655091753 0.0615448959807918 0.9509252603268727 1.0 1.0 3 Q8NEB9 1 +Positive regulation of microtubule nucleation 0.2674313311198342 0.061531839137689 0.950935658473008 1.0 1.0 6 Q14008,P51608,P0DMV9,Q13153,Q14203 5 +Vascular associated smooth muscle contraction 0.299689132741027 0.0599983137502429 0.9521569777049006 1.0 1.0 4 P61586 1 +Regulation of dna directed dna polymerase activity 0.1933534743202362 0.0590710306863148 0.9528955324998454 1.0 1.0 9 P12004,P35249,P0CG13,P40938,P40937,P35250,Q9BRX5,Q9BRT9 8 +Regulation of glucocorticoid metabolic process 0.5266807356044497 0.0562824377383192 0.955116809310512 1.0 1.0 2 P05023 1 +Prosthetic group metabolic process 0.5260777811275126 0.0559136658355494 0.9554105840992912 1.0 1.0 2 Q9Y697 1 +Activation of protein kinase c activity 0.5227615315043622 0.0539298182877109 0.9569910796698172 1.0 1.0 2 P35232 1 +Negative regulation of retinoic acid receptor signaling pathway 0.5218570997889533 0.053401681196033 0.957411865725296 1.0 1.0 2 P27797 1 +Positive regulation of spindle assembly 0.521555622550485 0.0532268537669689 0.9575511597254251 1.0 1.0 2 Q14204 1 +Sphingomyelin biosynthetic process 0.2894960782394596 0.0513415824059097 0.9590533338101852 1.0 1.0 4 Q9P0L0 1 +Neutrophil activation involved in immune response 0.3253408335094552 0.0511268721835635 0.9592244230838348 1.0 1.0 3 P51809 1 +Neutrophil degranulation 0.3253408335094552 0.0511268721835635 0.9592244230838348 1.0 1.0 3 P51809 1 +Vitamin b6 metabolic process 0.3241857659831261 0.0503330298002834 0.959857003143426 1.0 1.0 3 Q9NVS9,Q9Y617 2 +Glucocorticoid metabolic process 0.286468348664044 0.0490140352997275 0.960908110831832 1.0 1.0 4 P51608 1 +Cell cell junction maintenance 0.5137172143503073 0.0488910689689979 0.9610061062823728 1.0 1.0 2 Q96AC1 1 +Adherens junction maintenance 0.5137172143503073 0.0488910689689979 0.9610061062823728 1.0 1.0 2 Q96AC1 1 +Regulation of protein localization to chromatin 0.5125113053964303 0.0482591488812915 0.961509711066914 1.0 1.0 2 Q7Z5K2 1 +Regulation of behavior 0.2333066011463626 0.0478612718046853 0.961826804621019 1.0 1.0 7 Q9Y6A4,Q96QK1 2 +T cell lineage commitment 0.2570911285455581 0.0437298776397942 0.9651197230779212 1.0 1.0 5 P04637,P61586,P40763,P78527 4 +Calcium ion export 0.2789329457924626 0.0436817366487015 0.9651580973627109 1.0 1.0 4 O95202 1 +Lateral ventricle development 0.5025625565269684 0.0433879183775178 0.9653923083710704 1.0 1.0 2 Q00534 1 +N acetylneuraminate catabolic process 0.5010551703346257 0.0427014828454831 0.9659394975097746 1.0 1.0 2 P46926 1 +Centromeric sister chromatid cohesion 0.2245692150735781 0.042223536734498 0.9663204996883276 1.0 1.0 7 P49711,Q9GZZ1,P35222,O43683 4 +Mitochondrial fragmentation involved in apoptotic process 0.223731884057968 0.0417347360134218 0.9667101627403544 1.0 1.0 7 Q8N163,Q9Y3D6,Q07812,Q96QK1,Q9GZY8,Q9NT62 6 +Positive regulation of macrophage activation 0.31014406590699 0.0417103062242808 0.96672963793365 1.0 1.0 3 Q15046 1 +Positive regulation of interleukin 1 production 0.22131642512077 0.0403727882762923 0.9677959243654456 1.0 1.0 7 P19367,P49755,Q92769,Q99584,P40763,P04792 6 +L glutamate import across plasma membrane 0.3072979493365603 0.04018278215355 0.9679474043941404 1.0 1.0 3 Q15041,P05556 2 +Regulation of amino acid transmembrane transport 0.3072979493365603 0.04018278215355 0.9679474043941404 1.0 1.0 3 Q15041,P05556 2 +Regulation of l glutamate import across plasma membrane 0.3072979493365603 0.04018278215355 0.9679474043941404 1.0 1.0 3 Q15041,P05556 2 +Immune response to tumor cell 0.3054312920989329 0.0392190490295092 0.9687157463901784 1.0 1.0 3 P04439 1 +T cell mediated immune response to tumor cell 0.3054312920989329 0.0392190490295092 0.9687157463901784 1.0 1.0 3 P04439 1 +Negative regulation of translational elongation 0.4883931263189479 0.0374396834309682 0.9701344320352704 1.0 1.0 2 P38919 1 +Histone h2a phosphorylation 0.2456246228123051 0.0359964500377079 0.9712851895809476 1.0 1.0 5 Q9UIG0,Q13043,O60264,Q9Y4B6 4 +Regulation of collagen metabolic process 0.2979885886605644 0.0356651552047702 0.9715493549836738 1.0 1.0 3 P05556 1 +Regulation of cellular response to heat 0.2096346631930505 0.0347317792769257 0.9722936200091812 1.0 1.0 7 Q9UHD1 1 +Rescue of stalled ribosome 0.2351343193480259 0.0328557401837796 0.973789627939732 1.0 1.0 6 P63244,Q86UK7,Q8N3C0,O60524,Q9H1I8 5 +Regulation of mitophagy 0.233926954421977 0.0320668216681001 0.974418762269126 1.0 1.0 6 Q9NQ88,P05141,P04637,P12235,P49815 5 +Dopamine biosynthetic process 0.288600723763581 0.0318000552779038 0.9746315025545492 1.0 1.0 3 Q99497,Q96QK1 2 +Catechol containing compound biosynthetic process 0.288600723763581 0.0318000552779038 0.9746315025545492 1.0 1.0 3 Q99497,Q96QK1 2 +Mitotic intra s dna damage checkpoint signaling 0.2330214307274405 0.0314871547686805 0.9748810360764584 1.0 1.0 6 O96017,P49959,Q9BXW9,O60921,Q14676 5 +Negative regulation of glucose transmembrane transport 0.2864897466827615 0.0310194461741513 0.9752540313300382 1.0 1.0 3 O00186,Q01469 2 +Udp glucose metabolic process 0.2864897466827612 0.0310194461741513 0.9752540313300382 1.0 1.0 3 Q16851,Q9NYU2 2 +Regulation of calcium ion import 0.2338563669281776 0.0296359292354416 0.976357410503606 1.0 1.0 5 P14373,P35222,O14936,Q9NRA0 4 +Positive regulation of inclusion body assembly 0.4597527886644388 0.0284841837491323 0.977275982451479 1.0 1.0 2 P62195 1 +Meiotic chromosome condensation 0.2302353651176771 0.0279691531449251 0.9776867537418324 1.0 1.0 5 Q9NTJ3,O95347,Q6IBW4,Q15021 4 +Negative regulation of chromatin organization 0.4567380162797558 0.0277478831706832 0.9778632331418308 1.0 1.0 2 O75151 1 +Regulation of er to golgi vesicle mediated transport 0.2266329720316345 0.0276815398685543 0.9779161471126508 1.0 1.0 6 Q9HCU5 1 +Response to corticosterone 0.2756332931242561 0.0274745664698715 0.9780812252047344 1.0 1.0 3 P20020,P07196 2 +Response to tumor cell 0.245922947391391 0.0271202757323458 0.978363803011836 1.0 1.0 4 P04439 1 +Collagen biosynthetic process 0.23841754737019 0.024650662493512 0.9803336087337258 1.0 1.0 4 P50454 1 +Positive regulation of calcineurin mediated signaling 0.4398552909255274 0.0242345130029952 0.9806655488128326 1.0 1.0 2 P26599 1 +Proximal tubule development 0.4314139282484097 0.0228249504099534 0.9817899056580526 1.0 1.0 2 P24752 1 +Primitive hemopoiesis 0.4256858607175019 0.0219839359123925 0.9824607697270176 1.0 1.0 2 Q13769 1 +Changes to dna methylation involved in embryo development 0.4244799517636306 0.021817983731189 0.98259314865836 1.0 1.0 2 P26358 1 +Negative regulation of schwann cell proliferation 0.4178474525173312 0.0209700915465035 0.9832695139159486 1.0 1.0 2 Q9UPY3 1 +Schwann cell proliferation 0.4178474525173312 0.0209700915465035 0.9832695139159486 1.0 1.0 2 Q9UPY3 1 +Response to indole 3 methanol 0.2213056639433082 0.0203993340331026 0.9837248151052768 1.0 1.0 4 P14923 1 +Cellular response to indole 3 methanol 0.2213056639433082 0.0203993340331026 0.9837248151052768 1.0 1.0 4 P14923 1 +Mirna loading onto risc involved in gene silencing by mirna 0.4048839312631861 0.019599845233982 0.9843625872956888 1.0 1.0 2 Q9UPY3 1 +Positive regulation of gastrulation 0.3904130238166985 0.0184478363276342 0.9852815910533904 1.0 1.0 2 P63244 1 +Nephron tubule formation 0.3904130238166954 0.0184478363276342 0.9852815910533904 1.0 1.0 2 P35222 1 +Embryonic skeletal joint morphogenesis 0.3904130238166954 0.0184478363276342 0.9852815910533904 1.0 1.0 2 P35222 1 +Mesenchyme morphogenesis 0.3904130238166978 0.0184478363276342 0.9852815910533904 1.0 1.0 2 Q96A65 1 +Limb joint morphogenesis 0.3904130238166954 0.0184478363276342 0.9852815910533904 1.0 1.0 2 P35222 1 +Embryonic skeletal joint development 0.3904130238166954 0.0184478363276342 0.9852815910533904 1.0 1.0 2 P35222 1 +Positive regulation of transcription from rna polymerase ii promoter in response to stress 0.3898100693397629 0.0184072471153131 0.9853139710610586 1.0 1.0 2 Q92616 1 +Positive regulation of execution phase of apoptosis 0.3898100693397585 0.0184072471153128 0.9853139710610588 1.0 1.0 2 P63167 1 +Regulation of mitochondrial electron transport nadh to ubiquinone 0.3825746156165183 0.0179608353006225 0.985670097269705 1.0 1.0 2 Q9H1K1 1 +Positive regulation of lyase activity 0.3825746156165183 0.0179608353006225 0.985670097269705 1.0 1.0 2 Q9H1K1 1 +Intrinsic apoptotic signaling pathway in response to hydrogen peroxide 0.3825746156165195 0.0179608353006225 0.985670097269705 1.0 1.0 2 Q12931 1 +Response to glycoside 0.3705155260777805 0.0173650834426184 0.9861453643295256 1.0 1.0 2 P05023 1 +Hepatocyte differentiation 0.3515224600542659 0.016722465269592 0.9866580249725894 1.0 1.0 2 Q16822 1 +Behavioral response to cocaine 0.3466988242387713 0.0166042434325471 0.9867523392561536 1.0 1.0 2 Q00535 1 +Protein demannosylation 0.3231835996382289 0.0162119144384934 0.9870653303658968 1.0 1.0 2 Q9NYU2 1 +Phospholipase c activating dopamine receptor signaling pathway 0.3090141694302133 0.0160805656367342 0.9871701178868256 1.0 1.0 2 P29992 1 +Regulation of ribonuclease activity 0.3050949653301221 0.0160537862215999 0.9871914820109116 1.0 1.0 2 P06748 1 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e55a1e5f17e72dae554fbb7c0aef9ff56a2be026 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in prostate gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bud elongation involved in lung branching", "Bundle of his cell to purkinje myocyte communication", "Bundle of his cell to purkinje myocyte signaling", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac muscle tissue regeneration", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to progesterone stimulus", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary vasculature development", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Corticotropin secretion", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindgut development", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L kynurenine metabolic process", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral mesoderm development", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene d4 metabolic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cardiocyte differentiation", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of creb transcription factor activity", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of epithelial to mesenchymal transition", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hexokinase activity", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of sterol transport", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin d biosynthetic process", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Noradrenergic neuron development", "Noradrenergic neuron differentiation", "Nose development", "Notch receptor processing", "Notch signaling pathway", "Notochord development", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet dense granule organization", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transmembrane transport", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermal growth factor activated receptor activity", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial cell proliferation involved in wound healing", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix constituent secretion", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage derived foam cell differentiation", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide mediated signal transduction", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell population maintenance", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prostate gland morphogenesis", "Prostate glandular acinus development", "Prostate glandular acinus morphogenesis", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Receptor transactivation", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of acrosome reaction", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen processing and presentation", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in prostate gland morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcidiol 1 monooxygenase activity", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of corticotropin secretion", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix constituent secretion", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somitogenesis", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d biosynthetic process", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urogenital system development", "Uronic acid metabolic process", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d biosynthetic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C19orf70", "C1QBP", "C20orf27", "C21orf59", "C2CD5", "C2orf49", "C5orf51", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC88A", "CCDC94", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPE", "CENPI", "CENPU", "CENPV", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG2", "COG3", "COG4", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAM118B", "FAM160A2", "FAM162A", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISG20L2", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1211", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAR2", "AARS2", "ABCC4", "ABHD14B", "ABT1", "ACAT1", "ACLY", "ACO2", "ACOT7", "ACSF3", "ACSL3", "ACTR2", "ACTR6", "ADAM17", "ADAR", "ADH5", "ADNP", "ADRM1", "AFDN", "AFG3L2", "AGK", "AGPS", "AHNAK", "AK1", "AK3", "AK4", "AKAP12", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH4A1", "ALDH6A1", "ALDOC", "ALG1", "ALG5", "ALKBH5", "ALYREF", "ANKLE2", "ANXA1", "AP1G1", "AP1M1", "AP2S1", "AP3B1", "AP3D1", "APOO", "APPL1", "AQR", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP2", "ARHGAP1", "ARHGEF2", "ARL6IP1", "ARL8B", "ARMC1", "ARMC10", "ARPC1B", "ARPC2", "ASCC2", "ASCC3", "ASPH", "ASRGL1", "ATAD2", "ATG3", "ATG4B", "ATG9A", "ATL3", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5F1", "ATP5J2", "ATP5O", "ATP6AP2", "ATP6V1C1", "ATP6V1D", "ATPAF1", "ATPIF1", "ATRX", "ATXN2", "BAG6", "BASP1", "BAX", "BAZ1B", "BCAT2", "BDH2", "BIRC6", "BLM", "BLOC1S1", "BOD1L1", "BOP1", "BRAT1", "BRCA1", "BRIX1", "BSG", "BUB1", "BUD23", "BYSL", "C12orf43", "C12orf73", "C1QBP", "C20orf27", "C21orf59", "CAB39", "CADM1", "CALR", "CAP1", "CAP2", "CAPN2", "CAPZB", "CASK", "CASP3", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCNA2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC42", "CDC42BPB", "CDCA8", "CDH2", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CELF1", "CENPU", "CENPV", "CFAP20", "CFL2", "CHD4", "CHEK2", "CHMP2A", "CHORDC1", "CHP1", "CHTF18", "CHTF8", "CHTOP", "CIAPIN1", "CIZ1", "CKAP2", "CKAP5", "CLASP2", "CLPB", "CLPTM1", "CMAS", "CNOT1", "CNOT11", "CNOT3", "CNOT9", "COG2", "COG3", "COG4", "COLEC12", "COLGALT1", "COMTD1", "COQ8A", "CORO1C", "COX2", "COX5A", "COX6C", "COX7A2L", "CPT2", "CRNKL1", "CSNK2B", "CSTF2", "CTCF", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CUL1", "CUL2", "CUL4B", "CUL5", "CXorf57", "CYC1", "DCAF1", "DCAKD", "DCD", "DCTD", "DCTN1", "DDB1", "DDOST", "DDT", "DDX10", "DDX18", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX3X", "DDX46", "DDX47", "DDX49", "DDX5", "DDX54", "DDX56", "DENND4C", "DERL1", "DHCR7", "DHRS7", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX9", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC10", "DNAJC11", "DNM2", "DNMT1", "DPM1", "DPYSL5", "DSG2", "DSP", "DUSP3", "DVL2", "DYM", "DYNC1H1", "DYNLL1", "EBNA1BP2", "EBP", "ECI1", "ECT2", "EEF1E1", "EEFSEC", "EHMT2", "EIF2A", "EIF2B3", "EIF2B4", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3G", "EIF3I", "EIF3M", "EIF4A3", "EIF4G1", "EIF4H", "EIF6", "EMC3", "ENAH", "ENO1", "ENO2", "EPB41L2", "EPB41L5", "EPDR1", "EPN1", "EPPK1", "ERAL1", "ERBIN", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ESD", "ESF1", "ESS2", "ESYT2", "ETFB", "EXOC1", "EXOC4", "EXOC6B", "EXOSC10", "EXOSC2", "EXOSC6", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAH", "FAM118B", "FAM162A", "FANCA", "FANCD2", "FAR1", "FARSA", "FASTKD2", "FASTKD5", "FBL", "FDXR", "FECH", "FEN1", "FERMT2", "FHOD1", "FIS1", "FKBP2", "FKBP8", "FLNA", "FLNB", "FOXRED1", "FSCN1", "FTSJ3", "FUNDC2", "G3BP2", "GALK1", "GALM", "GAPDH", "GBE1", "GCDH", "GCN1", "GDAP1", "GEMIN4", "GFM1", "GFPT1", "GGA1", "GINS3", "GINS4", "GLMN", "GLO1", "GLYR1", "GNA11", "GNA13", "GNAI3", "GNE", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GOT2", "GPAM", "GPD2", "GPHN", "GPT2", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSTA4", "GSTK1", "GSTM2", "GTF2B", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP3", "GTPBP4", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAGH", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HEATR1", "HERC4", "HEXIM1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HMGA1", "HMGB1", "HMGB3", "HMGN1", "HMGN2", "HNRNPA1", "HNRNPA2B1", "HNRNPD", "HNRNPM", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPS6", "HSD17B11", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTT", "HUS1", "HYOU1", "IARS", "IBA57", "ICMT", "IDH3A", "IDH3B", "IFT27", "IFT88", "IGF1R", "IGF2BP1", "IGF2BP2", "ILF3", "ILK", "ILVBL", "IMPAD1", "INA", "INCENP", "INTS1", "INTS12", "INTS3", "INTS7", "IPO11", "IQGAP2", "IRS4", "ISCU", "ISG20L2", "ISOC2", "ISY1", "ITCH", "ITGB1", "IVD", "JAGN1", "JUP", "KARS", "KCTD12", "KDELC2", "KDM1A", "KIAA0391", "KIF14", "KIF1B", "KIF20A", "KIF22", "KIF3A", "KNTC1", "KRR1", "LAMC1", "LAMTOR1", "LAMTOR2", "LARP7", "LARS2", "LAS1L", "LDHA", "LDHB", "LDLRAP1", "LETM1", "LIMA1", "LLGL1", "LONP1", "LPGAT1", "LSM6", "LYAR", "LYPLA1", "LZTFL1", "MACF1", "MAD1L1", "MAN2A1", "MANF", "MAP1S", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPRE2", "MARCH5", "MAT2A", "MAT2B", "MAVS", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM5", "MCM7", "MCU", "MDC1", "MDH1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED21", "MED23", "MFF", "MFN2", "MGME1", "MIA3", "MIF", "MIPEP", "MKI67", "MLEC", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MPC2", "MPHOSPH6", "MPP2", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL16", "MRPL19", "MRPL2", "MRPL43", "MRPL55", "MRPS11", "MRPS15", "MRPS16", 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0.003738860453444 30.43446601941747 62.24029126213592 -1.4197947775299136 0.3409591614198546 9.966598413609615 3.609995281795233 1.4605024846200096 0.3544803128291746 0.0584635742500571 0.0437228444640497 0.0135718056008213 2.9520324087247485e-05 +Cytosolic ribosome 58 79 2.866974465626213 0.0041441644735393 39.64320388349515 77.44174757281553 -1.1028816270052657 0.3250092147697844 13.34244185985737 1.652889454237942 2.1520560160639124 0.378169291857921 0.3619523256513019 0.0599224496562618 0.0003770900328006 1.2891595297458936e-15 +Large ribosomal subunit 30 76 2.8363642528275603 0.0045630371403966 31.475728155339805 75.75242718446601 -0.701093514105986 0.409479351501158 11.239532053447306 4.0694062127427815 1.520999775598302 0.3546603200435178 0.0951142950684223 0.0858549547079452 0.0044565568247638 3.157771944531814e-11 +Organellar ribosome 11 46 2.797694777105279 0.0051468724193635 14.32766990291262 44.70873786407767 -0.3272491785902703 0.5734070752038083 8.382941034976346 5.414168876254706 1.0854266224547742 0.352666266494737 0.0584635742500571 0.0077976080130679 0.0135718056008213 0.0017180115940075 +Small ribosomal subunit 23 48 2.765710114700832 0.0056799000913305 20.449029126213592 46.01456310679612 -0.7960611028811027 0.4330047659653036 7.793750547784642 2.806853878031322 1.2350903949880847 0.354189214621263 0.270648213584465 0.0035281458113583 0.0046755148880645 1.0685947206761277e-05 +Transcription export complex 2 9 2.3576250711706925 0.0183922584559934 4.092233009708738 8.383495145631068 -0.8137880174622876 0.4173995878253959 2.0624327853896633 0.991967456342422 0.8373993625865013 0.3116071077154949 1.2998708524751297e-05 0.0001045037164678 0.00153832558414 0.0009470318558772 +Mrna editing complex 0 5 2.2981886459302423 0.0215510546389769 1.908641975308642 3.6938271604938273 -0.5930449371981953 0.4211216015644477 1.2308982498354404 1.331512245161641 1.0462466775858188 0.3021964880054596 0.0385773062479974 0.0758460972151271 0.1801790130745941 0.3312855510139293 +Mediator complex 2 11 2.269215055075998 0.0232552511787544 3.648058252427184 10.907766990291265 -0.0062979208678858 0.6409618157229141 2.299202292333729 3.003434581527006 0.7420558120855871 0.2879219461824036 0.1828652209005429 0.3329579057594876 0.0785959282355589 0.3261850209273007 +Polysome 13 49 2.1576199695478 0.0309573907930484 18.1504854368932 46.30825242718446 -0.3464905176104448 0.5270213705911827 7.423504704278708 2.0168296408864546 1.1797990698219971 0.3537616634296595 0.2670314735990955 0.1267862934099702 0.0684092062727696 8.907263224954718e-06 +Polysomal ribosome 11 26 2.0798570465607216 0.0375386468165692 12.57766990291262 25.67233009708738 -0.6096975471652369 0.4252058931739489 5.190664361369856 0.8371886656600765 1.290081657729728 0.3517767491710444 0.141543756104335 0.2636091346473535 0.0395166683685705 1.0197088203377102e-08 +Sm like protein family complex 17 54 2.072095522307094 0.0382565338390312 20.32766990291262 49.842233009708735 -1.0109308840679758 0.4225503229099085 7.470453866962472 3.2113063101409582 1.0331863080790435 0.3507144637016726 0.0058478787222266 0.0008229131747765 0.0004770748912342 0.0034574073035726 +Cytoplasmic exosome rnase complex 6 11 2.0480159732227623 0.0405584342903702 5.240291262135922 10.890776699029129 -0.643260537089687 0.4831525923392004 2.5567401712954494 1.0544461476490945 0.7661180741206842 0.2994369080353751 1.0 0.1203280145079081 0.2759666252930612 0.0232044770208039 +U5 snrnp 9 11 2.041229425393213 0.0412280282049819 5.907766990291262 10.968446601941748 -0.954368902748658 0.362082267661525 2.3834457116262544 0.6729694482044549 0.830118691856684 0.2963259711167147 1.0 1.0 0.0064387619157215 0.0407613761188157 +Dna packaging complex 11 27 2.0365086234622205 0.0416993080622098 11.567961165048544 27.186893203883496 -1.2682557115551525 0.3162623166266461 4.155677216135228 2.6506132388548593 1.3109592750478818 0.3330893937172427 1.0 0.1106573079891401 0.0005068824278338 1.9159873565214744e-05 +Cytosolic small ribosomal subunit 18 32 2.030075866340412 0.0423488282323281 15.883495145631068 31.228155339805824 -0.7650195110263021 0.3906488481560163 6.562324018350595 1.3568894665422215 1.394517750034202 0.3525264467590816 0.1706778675257841 0.0060217503205503 0.0135456883876511 6.947460484847665e-05 +Spliceosomal snrnp complex 19 42 2.0218045993988123 0.0431965424374531 18.1626213592233 41.47330097087379 -1.128624172705727 0.3824038000335636 6.926469625862109 2.3825347065390536 1.0666594993374927 0.3462824091290538 0.0306743412959273 0.0021648846033271 0.0004075671461417 0.001472880567168 +Retromer complex 1 11 2.007487546904618 0.0446977753020321 3.8932038834951457 8.861650485436893 -0.0417011237299978 0.5913523591909454 2.2999055335569523 0.9541860732087792 0.848315533513102 0.3034434293986225 0.0573151884822011 0.0058956460302812 0.0336123253792317 0.1144905971504207 +Core mediator complex 2 7 2.001941276589172 0.0452910476386927 2.388349514563106 6.065533980582524 -0.1231984313833298 0.5279604298749278 1.7291504716385229 2.3313141542354443 0.97921984877385 0.3086801197294866 0.1244478155008913 0.2339121686337894 0.0276080433055301 0.1441568547168213 +Exoribonuclease complex 8 16 1.9669791385104107 0.0491856158718664 6.29126213592233 14.240291262135925 -0.5904627470814516 0.5292022624801693 3.201580519757178 1.413536470013976 0.7516044241952305 0.3106605651049764 1.0 0.0161297090986061 0.012195883686582 0.0023331236629958 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c98316870357a47ebf0a2e7dc6e6faafd6d1ff9f --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 904, + "title": "Average number of proteins per term", + "value": 29.946902654867255 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9fd1f87063da30242895aff6f081cb36b24d1383 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5cb89ace6e935f83edacb425e103edf792a0f47f --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,325 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytosolic large ribosomal subunit 0.5857669282836615 3.2176627901793595 0.0012923966354818 0.6893480670588632 0.3469695971851022 46 P83731,Q02878,P62424,P18077,Q9Y3U8,P61513,P62750,Q9BYD6,P46776,P26373,P63173,P61353,P36578,P62910,P83881,P62899,P84098,P39023,P32969,P62917,Q6DKI1,P47914,P61313 23 +Preribosome 0.528242510517218 2.8993929065292616 0.003738860453444 0.9661651582584808 0.5134629682562836 61 Q14137,Q9BSC4,O00541,Q8NEF9,P22087,Q9BVJ6,P55769,Q2NL82,Q68CQ4,O00567,Q9NQ55,Q9Y4W2,Q8TCT8,Q13601,P62081,O76021,Q12788,Q14684,Q9BXY0,O95478,Q99848,O15213,Q14690,Q9Y3A2,Q9H9Y2,Q13895,Q969S3,Q8IY81,Q9H583 29 +Cytosolic ribosome 0.5630145258266466 2.8669744656262135 0.0041441644735393 0.9765786877303876 0.5134629682562836 79 P83731,Q02878,P62424,P61513,P18077,Q9Y3U8,P62269,P50914,P62750,P62701,P62280,P62841,P62857,P39019,Q9BYD6,P82912,P08708,P05388,P30050,P62277,P61927,P46777,P40429,P62241,P62854,P46776,P62081,P62851,P62753,P62266,Q7Z478,Q02543,P26373,P63173,P61247,Q9BY44,P61353,P36578,P62910,P62847,P83881,P18124,P62899,P15880,P84098,P39023,P32969,P60866,P62917,Q6DKI1,P47914,P62263,P25398,P46781,P46778,P61254,P61313,P62244 58 +Large ribosomal subunit 0.5536724927276404 2.8363642528275603 0.0045630371403966 0.983988139236418 0.5134629682562836 76 Q7Z7F7,P83731,Q5T653,Q02878,P62424,P18077,Q9Y3U8,P61513,P62750,Q9BYD6,Q567V2,P46776,P26373,P63173,P61353,P36578,P62910,P83881,Q8N983,P62899,P84098,P39023,P32969,P62917,P49406,Q6DKI1,P47914,P61313,Q9NX20,Q9H2W6 30 +Organellar ribosome 0.5387516783983511 2.797694777105279 0.0051468724193635 0.9905787502039166 0.5134629682562836 46 Q7Z7F7,Q5T653,P49406,P82664,Q9Y3D3,P82675,Q8N983,Q9Y2R9,Q567V2,P82912,Q9H2W6 11 +Small ribosomal subunit 0.5042946397694311 2.765710114700832 0.0056799000913305 0.9941963440697612 0.5134629682562836 48 P62269,P82914,P62841,P62701,P62280,Q9Y3D3,P62857,P39019,P82912,P08708,P62277,P62854,P62753,P62081,Q7Z478,P61247,Q9BY44,P62847,P82675,Q9Y2R9,P60866,P82664,P62244 23 +Transcription export complex 0.778959525160794 2.3576250711706925 0.0183922584559934 0.999999948485528 0.7540203654009932 9 Q86V81,Q9Y3Y2 2 +Mediator complex 0.727404123209965 2.269215055075998 0.0232552511787544 0.9999999994217696 0.7540203654009932 11 O60244,Q13503 2 +Polysome 0.4296268671064223 2.1576199695478 0.0309573907930484 0.9999999999995492 0.7540203654009932 49 P84098,P83731,O43347,P63173,Q8TCS8,P62917,Q02878,P62424,Q9Y3U8,P62910,P62857,P83881,P62899 13 +Polysomal ribosome 0.6460926933347292 2.0798570465607216 0.0375386468165692 0.999999999999999 0.7540203654009932 26 P84098,P83731,P63173,Q8TCS8,Q02878,P62424,Q9Y3U8,P62910,P62857,P83881,P62899 11 +Sm like protein family complex 0.4321438375909475 2.072095522307094 0.0382565338390312 0.9999999999999996 0.7540203654009932 54 Q9Y312,P09234,O95391,Q15428,P08621,Q96DI7,O94906,P08579,P55769,P62318,O95400,Q9BUQ8,P62314,P57678,Q9BWJ5,P62312,P09012 17 +Cytoplasmic exosome rnase complex 0.6836861364067076 2.0480159732227623 0.0405584342903702 1.0 0.7540203654009932 11 Q8IYB8,Q8TCS8,Q13868,Q5RKV6,Q96B26,Q06265 6 +U5 snrnp 0.6823589675446114 2.041229425393213 0.0412280282049819 1.0 0.7540203654009932 11 Q6P2Q9,Q96DI7,P62304,O94906,O95400,P62318,Q9BUQ8,P62314,Q9Y312 9 +Dna packaging complex 0.6332461613778052 2.0365086234622205 0.0416993080622098 1.0 0.7540203654009932 27 P10412,O75367,P16403,Q9P0M6,Q5SSJ5,Q9HAF1,Q92522,Q49A26,Q9NPF5,P62805,P07305 11 +Cytosolic small ribosomal subunit 0.598266579959112 2.030075866340412 0.0423488282323281 1.0 0.7540203654009932 32 P08708,P60866,P62277,P61247,P62269,P62841,Q9BY44,P62701,P62280,P62854,P62753,P62857,P62081,P62847,P39019,Q7Z478,P82912,P62244 18 +Spliceosomal snrnp complex 0.5031071131594538 2.0218045993988123 0.0431965424374531 1.0 0.7540203654009932 42 P09234,P55769,P09012,Q15428,P08621,O94906,Q9BWJ5,P62318,P62314,P08579,Q13435,P62312,Q6P2Q9,Q96DI7,P62304,O95400,Q9BUQ8,Q9Y312,Q86UA1 19 +Retromer complex 0.6757721582022584 2.007487546904618 0.0446977753020321 1.0 0.7540203654009932 11 Q9UMY4 1 +Core mediator complex 0.7595157837160919 2.001941276589172 0.0452910476386927 1.0 0.7540203654009932 7 O60244,Q13503 2 +Exoribonuclease complex 0.6635804319945592 1.9669791385104107 0.0491856158718664 1.0 0.7540203654009932 16 Q8IYB8,Q8TCS8,Q13868,Q5RKV6,Q9Y4W2,Q96B26,Q99547,Q06265 8 +Protein dna complex 0.4238112591106144 1.9404171494175195 0.0523290140806704 1.0 0.7540203654009932 56 O75367,P16403,P16402,P09874,Q15554,Q5SSJ5,P62805,P06748,Q15022,P10412,Q00403,P33992,Q9NRA0,Q9UBU8,Q92522,Q9NPF5,P07305,P14923,Q9Y2S7,P13984,Q9HAF1,P11387,Q9P0M6,P28340,P49005,Q49A26 26 +Catalytic step 2 spliceosome 0.4497369398331991 1.895392783899264 0.0580403839954419 1.0 0.7540203654009932 71 Q9NW64,Q96DF8,Q86V81,Q9UMS4,Q9UQ35,O75643,O60306,O95391,Q15428,O94906,P62316,P52272,Q9ULR0,Q13523,P42285,Q15393,Q9UKM9,Q13573,Q96BP3,Q9UNP9,Q92620,Q99459,P62318,Q00839,P62314,P08579,Q13435,Q9BZJ0,Q9Y5S9,Q9H2H8,Q9Y3C6,Q6P2Q9,Q96DI7,P62304,P22626,Q9BUQ8,Q8IYB3,P31943 38 +Cytoplasmic side of endoplasmic reticulum membrane 0.733658881621172 1.8868384532993667 0.059182057324546 1.0 0.7540203654009932 7 Q8TCT8,P62857 2 +Golgi transport complex 0.7805097010700467 1.8708294658659277 0.0613687220340775 1.0 0.7705183988723064 5 Q96JB2,P60953 2 +Sex chromosome 0.674093334919478 1.8550790951541043 0.0635849325457544 1.0 0.7713145912356266 9 Q15022,O75367,Q12824,Q9P0M6,Q00839,Q96SB8,A6NHR9 7 +Ribosomal subunit 0.5400001303054878 1.852172045052908 0.0640011216619145 1.0 0.7713145912356266 123 Q7Z7F7,P83731,Q5T653,Q02878,P62424,P61513,P18077,P82914,Q9Y3U8,P50914,P62269,P62701,P62280,P62750,P62841,P62857,Q9Y3D3,Q9BYD6,Q567V2,P82912,P62277,P46776,P62081,Q7Z478,P26373,P63173,Q9BY44,P61353,P36578,P62910,P62847,P82675,Q8N983,Q9H2W6,P83881,P62899,Q9Y2R9,P84098,P39023,P32969,P60866,P62917,P49406,Q6DKI1,P82664,P47914,P61313,Q9NX20,P62244 49 +Mitochondrial large ribosomal subunit 0.5848743553388468 1.846164521724172 0.0648683206521714 1.0 0.7713145912356266 30 Q7Z7F7,Q5T653,Q8N983,Q567V2,Q9H2W6 5 +Caspase complex 0.7704680843048207 1.8284152768431 0.0674872503352506 1.0 0.7713145912356266 5 Q96S52,P17655 2 +U2 type spliceosomal complex 0.4264789585119484 1.8190129986356225 0.06890944697972 1.0 0.7713145912356266 63 Q9NW64,P09234,P55769,Q9UMS4,O60306,Q15428,P08621,O94906,Q9ULR0,Q9BWJ5,Q9UNP9,P62318,P62314,P08579,Q13435,Q9BZJ0,P62312,Q9Y3C6,Q6P2Q9,Q96DI7,P62304,Q15427,Q86UA1 23 +Bleb 0.7664001578652797 1.8111892313175673 0.0701115645741152 1.0 0.7713145912356266 5 Q9BRK5 1 +Rna polymerase i complex 0.6901070087193732 1.8038812369877484 0.0712499269801476 1.0 0.7713145912356266 8 P62875,O15446,Q9GZS1,O15160,O95602,Q9H9Y6 6 +Clathrin vesicle coat 0.6356349636398554 1.7990274367387682 0.0720143407461235 1.0 0.7713145912356266 12 Q9Y6I3 1 +Spectrin 0.8126506574707013 1.771098682191663 0.0765442931286446 1.0 0.7724575745056278 4 O15020 1 +Transcription factor tfiiic complex 0.7502657298743823 1.7426267010451373 0.0813988428335319 1.0 0.7768979562070355 5 Q9Y5Q8,Q9Y5Q9,Q12789 3 +Rna polymerase iii transcription regulator complex 0.7502657298743823 1.7426267010451373 0.0813988428335319 1.0 0.7768979562070355 5 Q9Y5Q8,Q9Y5Q9,Q12789 3 +Sno s rna containing ribonucleoprotein complex 0.6225225314328752 1.737208893984221 0.0823503056118379 1.0 0.7768979562070355 15 P22087,Q8N5L8,Q96DI7,P55769,P62312,O60832 6 +Respirasome 0.4140681294384363 1.7315044144583416 0.0833618382213301 1.0 0.7768979562070355 47 O14548,P20674,P19404,P09669,O75438,O43676,P03915,Q86Y39,O95139,O95168,O75380,Q9P0J0,P28331,P08574,Q96CU9,Q9UDW1,O14949 17 +Nuclear exosome rnase complex 0.6153306679719094 1.697155794892717 0.0896672099901167 1.0 0.7804261042218728 10 Q96B26,Q5RKV6,Q06265,Q13868 4 +Postsynaptic endosome 0.8516284680337758 1.6430314627355325 0.1003764237640352 1.0 0.8401878433582206 3 P20339,P20338 2 +Tricarboxylic acid cycle enzyme complex 0.6048174587890784 1.6383443411476353 0.1013498827947092 1.0 0.8405531563891483 11 P36957,P50213,Q02218,Q96I99,Q9P2R7 5 +Preribosome large subunit precursor 0.593208339165477 1.6226966926103763 0.1046542587681669 1.0 0.8452860109974374 20 Q14137,O00541,Q14684,Q9Y4W2,O95478,Q99848,Q9H9Y2,Q969S3,Q8IY81 9 +Insulin responsive compartment 0.7755411734764329 1.621117820323982 0.1049923728540829 1.0 0.8452860109974374 4 Q5VZ89,P51153 2 +Small subunit processome 0.5351913681854497 1.5987591571176014 0.109874127419848 1.0 0.864616753191726 32 Q9BSC4,Q12788,P22087,Q9BVJ6,Q8TCT8,Q13601,P55769,Q9Y3A2,Q68CQ4,O15213,P62081,Q14690,Q9H583,O00567 14 +Dihydrolipoyl dehydrogenase complex 0.7669000098259278 1.5859846085623468 0.1127428010685056 1.0 0.8711067706489667 4 Q02218,P36957 2 +Intrinsic component of peroxisomal membrane 0.821953454170526 1.528515614100495 0.1263845698177799 1.0 0.9191325947702708 3 O43808 1 +Commitment complex 0.665983558550878 1.4842218714598652 0.1377500692736128 1.0 0.9505514333653076 6 P62318,P62314,P09234,Q86UA1 4 +Oxidoreductase complex 0.3854204486314825 1.4717803198120338 0.1410802097144645 1.0 0.9505514333653076 59 O75438,O43676,P50213,P38117,Q9UDW1,P10515,P19404,Q02218,P08559,P28331,Q96CU9,P14927,Q86Y39,O75380,P08574,P03915,P36957,O95139,O95168,Q9P0J0,Q16795,O14949 22 +Prp19 complex 0.5717937921032732 1.4638610381652737 0.1432319208269969 1.0 0.9505514333653076 11 Q9NW64,Q9BZJ0,Q8WYA6,Q9ULR0 4 +Nadh dehydrogenase complex 0.5406090438625156 1.4268564230370056 0.1536212837386545 1.0 0.9505514333653076 26 O95139,P03915,O75438,O43676,Q86Y39,O95168,O75380,P28331,Q96CU9,Q9P0J0 10 +Photoreceptor inner segment 0.6320227214510147 1.4241494103201588 0.1544032258153742 1.0 0.9505514333653076 7 P35613 1 +Dna replication factor c complex 0.6510935936167646 1.4181940886284956 0.1561341072962729 1.0 0.9505514333653076 6 P41440 1 +Clathrin coat of endocytic vesicle 0.6730939663379714 1.4102839191524883 0.1584558648884004 1.0 0.9505514333653076 5 O95782,P53680 2 +Myosin complex 0.5588740711616426 1.4011943573011505 0.1611559612208366 1.0 0.9505514333653076 10 O00159,O43795,Q92614 3 +Rna polymerase ii core complex 0.6268758781570218 1.4004057515439292 0.1613918486740306 1.0 0.9505514333653076 7 P19388,P24928,P62875,P62487 4 +Granular component 0.7197450640523033 1.393219793933264 0.1635533359154133 1.0 0.9505514333653076 4 O75683,Q14684 2 +Oxoglutarate dehydrogenase complex 0.7867913148371566 1.3921733798675118 0.1638699017478377 1.0 0.9505514333653076 3 Q02218,P36957 2 +Ribosome 0.5211647455748211 1.3853903974647803 0.1659331256246483 1.0 0.9505514333653076 142 Q7Z7F7,P83731,Q5T653,Q02878,P62424,P61513,P18077,P82914,Q9Y3U8,P50914,P62269,P62701,P62280,P62750,P62841,P62857,Q9Y3D3,Q9UHA3,Q9BYD6,Q567V2,P82912,Q8TCS8,P62277,P46776,P62081,Q7Z478,P26373,P63173,Q9BY44,P61353,P36578,Q9P2E9,P62910,P62847,P82675,Q8N983,Q9H2W6,P83881,P62899,Q9Y2R9,P84098,P39023,P32969,P60866,P62917,P49406,Q6DKI1,P82664,P47914,P61313,Q9NX20,Q15637,P62244 53 +B wich complex 0.6224824353779431 1.3801252284322258 0.1675480907564006 1.0 0.9505514333653076 7 O60264,Q9NR30,Q9NY93 3 +Clathrin coat of coated pit 0.552635045567333 1.3683403641666505 0.1712055617327526 1.0 0.9505514333653076 10 O95782,Q13492,Q9UBC2,P53680 4 +Spliceosomal tri snrnp complex 0.5448240866057416 1.333461459522972 0.1823804150697077 1.0 0.9505514333653076 19 Q6P2Q9,P62304,O94906,P55769,P62318,O95400,Q9BUQ8,P62314,P62312 9 +Rough endoplasmic reticulum 0.4707107121870104 1.3318793268818057 0.1828998453149335 1.0 0.9505514333653076 36 P04844,Q02878,Q9HD47,P61353,Q9UBF8,P62857,O60568,Q5VV42 8 +Mitochondrial pyruvate dehydrogenase complex 0.7040723981900463 1.328893128595725 0.1838832311561571 1.0 0.9505514333653076 4 P09622,P08559,P10515 3 +Golgi lumen 0.7015453520317436 1.3185157950414732 0.1873310411084792 1.0 0.9505514333653076 4 Q9BRK5 1 +Lateral element 0.6961828315735792 1.2964922437645698 0.19480595051705 1.0 0.9505514333653076 4 P54132 1 +U1 snrnp 0.5410306225148502 1.2927906930998838 0.196083460168297 1.0 0.9505514333653076 13 P09234,P62304,P08621,P62318,P62314,P08579,P09012 7 +H4 h2a histone acetyltransferase complex 0.5829637892023616 1.2924584511005397 0.1961984257880868 1.0 0.9505514333653076 8 Q9NPF5,Q9UBU8,Q9HAF1 3 +Barr body 0.7605548854041231 1.2902323645644558 0.196969992169611 1.0 0.9505514333653076 3 Q9P0M6,O75367 2 +X chromosome 0.7605548854041231 1.2902323645644558 0.196969992169611 1.0 0.9505514333653076 3 Q9P0M6,O75367 2 +Mitochondrial tricarboxylic acid cycle enzyme complex 0.6029116681003419 1.289691927716034 0.1971576434365696 1.0 0.9505514333653076 7 Q96I99,O43837,P09622,P50213 4 +U2 type catalytic step 2 spliceosome 0.5219707188798525 1.2883241046191205 0.1976331656708834 1.0 0.9505514333653076 25 Q9NW64,Q9Y3C6,Q6P2Q9,Q13573,P62304,Q9UNP9,Q96DI7,Q9BZJ0,P62316,Q99459,P62318,Q9UMS4,P62314,P08579,Q9UQ35,O60306 16 +Heterochromatin 0.5053655453958025 1.2866394758894266 0.1982199776879531 1.0 0.9505514333653076 29 Q15022,P10412,O75367,P46100,Q14684,Q02880,P42771,P17096,Q9NZM5,Q9NQS7 10 +Prespliceosome 0.5351566673132887 1.2696071099405708 0.2042246155232459 1.0 0.9505514333653076 11 Q15428,P09234 2 +Synaptonemal structure 0.555909215194893 1.2658874307171184 0.2055533870628849 1.0 0.9505514333653076 9 P54132,Q9NQS7 2 +Guanyl nucleotide exchange factor complex 0.688303234268915 1.26413011084853 0.2061833306398268 1.0 0.9505514333653076 4 Q6IAA8,Q9Y2Q5 2 +Tho complex 0.6392141573163891 1.262962364212875 0.2066027055746828 1.0 0.9505514333653076 5 Q86W42 1 +Gpi anchor transamidase complex 0.7530278106062831 1.26099031279538 0.2073123373523566 1.0 0.9505514333653076 3 Q96S52 1 +Anchored component of membrane 0.5759145730923227 1.2585414687284588 0.2081959997857643 1.0 0.9505514333653076 8 P20339 1 +Ino80 type complex 0.5504434017511529 1.238443181318842 0.2155517777064588 1.0 0.9622474593952806 9 Q9NPF5 1 +Trans golgi network 0.3724342411331903 1.237383052725908 0.2159449074617363 1.0 0.9622474593952806 64 P28838,Q96A57,Q92614,P53365,Q7Z6M1,Q96JB2,P61006,Q7Z3C6,Q10567,Q9NX62,O75122,O60568,P51153,O14828,O43795,Q99700,Q9H9E3 17 +Chromatin silencing complex 0.6287793120118224 1.217561557534048 0.223390630482883 1.0 0.9755803379542328 5 Q15022,O60264 2 +Telomerase holoenzyme complex 0.5242657385386936 1.206501784709098 0.227624071355615 1.0 0.9830286344262448 12 Q15185,Q9BUR4,P62304,P62318,Q9H0A0,O60832 6 +U4 snrnp 0.6021732568668896 1.2004567751074433 0.2299619903472325 1.0 0.9830286344262448 6 Q8WWY3,P62304,P62316,P62318,P62314 5 +Ribonuclease mrp complex 0.7361278648974735 1.1953952190799486 0.2319326527195064 1.0 0.9830286344262448 3 Q99575,Q8N5L8 2 +Sin3 complex 0.6710759910747295 1.1934118765324415 0.2327081059371862 1.0 0.9830286344262448 4 Q96ST3,Q9UBU8 2 +Golgi medial cisterna 0.6693329562123829 1.1862622797300375 0.2355187379126424 1.0 0.9835593092034224 4 Q16706,Q9BXS4 2 +Photoreceptor outer segment 0.5801100375879092 1.1843160345970456 0.2362879838559739 1.0 0.9835593092034224 7 P35613 1 +Preribosome small subunit precursor 0.5169323192792497 1.1732197143990517 0.240707708225242 1.0 0.9835593092034224 11 Q13895,Q8IY81,Q14684 3 +Catalytic step 1 spliceosome 0.5364940833681396 1.1685034077618244 0.2426037654679815 1.0 0.9835593092034224 9 Q9NW64,Q9UMS4,Q6P2Q9,Q9ULR0 4 +Swr1 complex 0.5766728720200907 1.1684487435873625 0.2426258030446495 1.0 0.9835593092034224 7 Q9NPF5 1 +Endoplasmic reticulum quality control compartment 0.6149668074833993 1.1575163939662805 0.2470614453166622 1.0 0.9955771778988662 5 P60468,Q9BUN8,Q9NYU2,P27797 4 +Intrinsic component of synaptic vesicle membrane 0.5527800333464739 1.1473905192947331 0.251220257750933 1.0 0.997226072509818 8 P20339,P20020,Q86Y82,Q15286 4 +Anchored component of synaptic vesicle membrane 0.6591849726751415 1.1446700533800978 0.2523458610898723 1.0 0.997226072509818 4 P20339 1 +Early phagosome 0.7192816160201088 1.1301589889659345 0.2584092371418722 1.0 1.0 3 P20339 1 +Ribonuclease p complex 0.6069686825328433 1.1227978678558572 0.2615233511232455 1.0 1.0 5 P78346,Q99575,O15091 3 +H4 histone acetyltransferase complex 0.5070300759919826 1.1210502186739002 0.262266486878318 1.0 1.0 11 Q9NPF5,Q9UBU8,Q9HAF1 3 +Intrinsic component of endoplasmic reticulum membrane 0.3349627849501284 1.087493631200086 0.2768187116925937 1.0 1.0 52 Q969N2,Q15125,Q96S52,Q86XL3,Q03518,Q8TCT8,P10321,Q9P2E9,Q9BUN8,Q9P0I2,P04439,P57088,Q8TB61 13 +Nucleoid 0.4432423919845363 1.0847885456311273 0.2780153198458037 1.0 1.0 35 Q8IYB8,Q7L8L6,P05141,Q9NYY8,Q9Y2S7,Q12849,P34897,Q9BRT2,P04179,P49411,P40939,Q7L2E3,Q00059,Q96AG4,Q9NUL7,P55084 16 +Precatalytic spliceosome 0.4481103197126111 1.0776340336301955 0.2811971077988631 1.0 1.0 34 Q5VTL8,Q6P2Q9,Q15428,P62304,Q15427,O94906,P08579,P55769,P62318,Q13435,P62314,Q9BWJ5,P62312 13 +Mhc class i peptide loading complex 0.6383107088989455 1.0593754375164448 0.2894288313820832 1.0 1.0 4 Q03518,P04439,P27797 3 +Post mrna release spliceosomal complex 0.5340591536956814 1.0578563458039325 0.2901209398809476 1.0 1.0 8 P52272,Q9BZJ0,Q9ULR0 3 +Mitochondrial permeability transition pore complex 0.5919290743986265 1.057674261269382 0.2902039735339623 1.0 1.0 5 P30405,P05141 2 +Endoribonuclease complex 0.4970033364324716 1.0539623385078674 0.2919001601747857 1.0 1.0 14 Q99575,Q8N5L8,Q9Y4W2,Q7L0Y3,P78346,O94992,O15091,Q9UPY3 8 +Pericentric heterochromatin 0.4905436981631439 1.04282744112801 0.2970282196702434 1.0 1.0 10 O75367,P46100 2 +Lumenal side of endoplasmic reticulum membrane 0.5291427119075081 1.0344416479301544 0.3009297427400677 1.0 1.0 8 Q8TCT8,P10321 2 +Esc e z complex 0.6939083232810599 1.032395988098271 0.3018866505984672 1.0 1.0 3 Q15022,Q92769 2 +Filopodium membrane 0.6909423719091524 1.0210211710641053 0.3072444083909598 1.0 1.0 3 P62330 1 +Potassium channel complex 0.683622104008895 0.9930055080034058 0.3207072702723581 1.0 1.0 3 Q96ER9 1 +Replication fork 0.4108184901559318 0.9880163986436892 0.3231446170519136 1.0 1.0 38 P54132,Q9Y2S7,Q7L590,Q9NPF5,P41440 5 +Apicolateral plasma membrane 0.6205128205128219 0.987075217900326 0.3236057657201241 1.0 1.0 4 P58107,P35222,P14923 3 +U2 snrnp 0.4849187303306681 0.9870458943558172 0.3236201402105412 1.0 1.0 16 Q15428,Q9BWJ5 2 +U12 type spliceosomal complex 0.4818419362436216 0.9734175094734538 0.3303458400881105 1.0 1.0 14 P62304,Q15427,P62316,Q8TBF4,P62318,P62314,Q13435,Q9BWJ5 8 +Nurd complex 0.5124771616413039 0.9554935744950376 0.3393281532147219 1.0 1.0 8 Q14839,Q92769,O94776,Q13330 4 +Dendrite membrane 0.671592279855252 0.9471701137558188 0.343552101726861 1.0 1.0 3 P20020,O75787 2 +Golgi associated vesicle membrane 0.4762663237856034 0.9437424873996396 0.3453012566748423 1.0 1.0 18 Q8N511 1 +Mitochondrial intermembrane space protein transporter complex 0.6649577804583776 0.9220157092279796 0.35652038161831 1.0 1.0 3 O60220,Q9Y5J9 2 +Respiratory chain complex iv 0.4677237804081652 0.91667367035282 0.3593136671862238 1.0 1.0 11 O14548,P09669 2 +Transcription preinitiation complex 0.6612107141803648 0.9078522002934494 0.3639563147599454 1.0 1.0 3 P13984 1 +Emc complex 0.5533587211683156 0.8923343354977935 0.3722137556908587 1.0 1.0 5 Q9P0I2 1 +Clathrin adaptor complex 0.4984040105423702 0.8894751905262027 0.3737477508509714 1.0 1.0 8 O95782,P53680 2 +Cohesin complex 0.5511427303587634 0.8829407925281604 0.3772682619813046 1.0 1.0 5 O60216 1 +Endoplasmic reticulum tubular network 0.4584160111704563 0.8617567451087265 0.3888213921339289 1.0 1.0 12 Q9H6H4,Q6NUK4 2 +Proton transporting v type atpase complex 0.4566512491705689 0.8602895156274641 0.3896294707924967 1.0 1.0 11 Q9Y5K8,Q8N511,O75787 3 +Unconventional myosin complex 0.5863049329021461 0.8498849191800423 0.3953890708319005 1.0 1.0 4 Q96FJ2,O00159 2 +Brush border membrane 0.4659488372513936 0.8214233279665485 0.411405180324615 1.0 1.0 9 P41440 1 +Eukaryotic translation initiation factor 2 complex 0.6367832268126128 0.8164154744771277 0.4142625490875358 1.0 1.0 3 Q9BY44 1 +Chromosome telomeric region 0.3594011159746374 0.8160256028838677 0.4144854925255772 1.0 1.0 81 P62140,O75367,P46100,P54132,Q96BK5,Q9P0M6,Q86V81,Q15554,Q96QC0,Q96SB8,O60934,Q8NI27,P62805,Q86W42 14 +Mitochondrial small ribosomal subunit 0.4519331800394579 0.8126535566123884 0.4164167160924248 1.0 1.0 16 P82664,Q9Y3D3,P82675,Q9Y2R9,P82912 5 +Xy body 0.632991556091691 0.8023817182291744 0.4223321849700983 1.0 1.0 3 Q12824,P16104 2 +Chromosome passenger complex 0.8836297859511608 0.7918796459889282 0.428430856122711 1.0 1.0 2 Q9NQS7 1 +Recycling endosome 0.3639660203559488 0.7899953558505358 0.4295304805506421 1.0 1.0 41 Q92930,Q96A57,Q15286,Q9HA65,P61006,P62330,Q7Z3C6,P10321,Q86Y82,O14828,P51153,P04439,P20338 13 +Recycling endosome membrane 0.4363327941993646 0.7797723552880936 0.4355248810346275 1.0 1.0 25 Q92930,Q15286,P61006,P62330,Q7Z3C6,P10321,Q86Y82,O14828,P51153,P20338 10 +Rough endoplasmic reticulum membrane 0.4447388209141374 0.7756306782237867 0.437967081185354 1.0 1.0 16 P62857,Q9UBF8 2 +Glycogen granule 0.6241714490781581 0.7699276395865597 0.4413428173192688 1.0 1.0 3 P62140 1 +Aminoacyl trna synthetase multienzyme complex 0.4383446543580478 0.7687520389700446 0.4420405256761803 1.0 1.0 11 P56192,P41252,P14868,P07814,O43324,Q15046 6 +Intraciliary transport particle b 0.6221665866351792 0.7625899734074935 0.4457079661047052 1.0 1.0 3 Q13099 1 +Intraciliary transport particle 0.6221665866351792 0.7625899734074935 0.4457079661047052 1.0 1.0 3 Q13099 1 +Signal recognition particle 0.4995635501745585 0.7511360552301373 0.4525707787993012 1.0 1.0 6 P09132,P61011,O76094 3 +Cell pole 0.5580904426077262 0.7393822652857441 0.45967490817523 1.0 1.0 4 Q92930 1 +T tubule 0.4653539112500336 0.7378329205647808 0.4606159855606131 1.0 1.0 8 P08069,Q09666 2 +Meiotic cohesin complex 0.5558513178139858 0.7307477673758856 0.464933232961076 1.0 1.0 4 O60216 1 +Nuclear inclusion body 0.4615543620435753 0.7207928307264845 0.4710369870328472 1.0 1.0 8 O60934,P49790 2 +Inner mitochondrial membrane protein complex 0.3442663783086522 0.7136853125396833 0.4754217905010864 1.0 1.0 79 P56134,O75438,O43676,Q9UDW1,P19404,P09669,Q8NE86,P28331,Q96CU9,Q96IX5,O14548,P20674,Q86Y39,O75380,Q5HYI7,P03915,O95139,O95168,Q99595,Q9P0J0,O14949 21 +Neuromuscular junction 0.4297760528111641 0.7001429344917316 0.4838380451973894 1.0 1.0 16 Q14168,P11047,P05556,P57105,P46939,Q8N9N2,O43760,Q00535 8 +Nuclear pore nuclear basket 0.472667261799065 0.7000519767536877 0.4838948451450942 1.0 1.0 7 Q8NFH5,Q9Y6D9 2 +Trans golgi network membrane 0.4140992054751177 0.6992862175339836 0.4843731785541696 1.0 1.0 28 P53365,Q7Z6M1 2 +Postsynaptic recycling endosome 0.8513717214350311 0.6910010110966677 0.4895649056447895 1.0 1.0 2 P20338 1 +Nsl complex 0.5978184123127881 0.6747970452494002 0.4998047179038827 1.0 1.0 3 P61964 1 +Proton transporting atp synthase complex catalytic core f 1 0.5383317142282829 0.6640143484572575 0.5066811276786569 1.0 1.0 4 P48047,P36542 2 +Oligosaccharyltransferase complex 0.4455876950215562 0.6503050171547033 0.5154952169242302 1.0 1.0 8 Q14165,P46977,P04844 3 +Paraspeckles 0.4751818037859906 0.6495830095612269 0.5159616108823566 1.0 1.0 6 O43809,P52272 2 +Sex chromatin 0.8362978595116011 0.6452131236857115 0.5187890826673158 1.0 1.0 2 O75367 1 +Ptw pp1 phosphatase complex 0.4729423363207168 0.6404310593716248 0.5218923957765937 1.0 1.0 6 P62140,Q96QC0,Q6UXN9 3 +Pcg protein complex 0.4889730946979864 0.6274775610227162 0.5303462404305523 1.0 1.0 5 Q15022,Q9UQR0,Q92769 3 +Cis golgi network 0.4087065304921662 0.6114272923958906 0.5409167389689813 1.0 1.0 13 Q16706,Q9Y3A6,Q96JB2,Q99996,Q8WVM8 5 +Nuclear outer membrane 0.4200744295473393 0.6096280248170957 0.5421082428004371 1.0 1.0 9 Q99720 1 +Bcl 2 family protein complex 0.822731383780519 0.604851658625617 0.5452775657389792 1.0 1.0 2 Q07820 1 +Synaptic vesicle membrane 0.4064599882974671 0.6009939398560893 0.5478440226610577 1.0 1.0 13 P20339,O43760,Q15286 3 +Arp2 3 protein complex 0.4489388830166129 0.6000748462674735 0.5484563553846906 1.0 1.0 7 O15144,O15143,P61160 3 +Rna polymerase iii complex 0.4806252884908562 0.5947928626091704 0.5519819390966827 1.0 1.0 5 O15160 1 +Set1c compass complex 0.4473434747629174 0.5935072925938581 0.5528417039591267 1.0 1.0 7 Q15291,Q8NFC6 2 +Chromocenter 0.4747906862199337 0.5722475203783673 0.5671542977783688 1.0 1.0 5 Q9NQS7 1 +Outer mitochondrial membrane protein complex 0.3989382306154067 0.5526741969736018 0.5804865251384239 1.0 1.0 16 Q9NS69,Q5HYI7 2 +Pml body 0.3922590633825333 0.5457546305647492 0.5852346136951563 1.0 1.0 25 P46100,P54132,Q9ULX6,Q9UBW7,Q96SB8 5 +Ccr4 not complex 0.4460380959072244 0.5333266027425575 0.5938075155103459 1.0 1.0 6 Q9UKZ1 1 +9plus0 non motile cilium 0.3885169163996078 0.5271048222819887 0.5981207981624288 1.0 1.0 12 P35613 1 +Cortical actin cytoskeleton 0.360892457818377 0.5209518172094273 0.6024003369987998 1.0 1.0 34 P41440,O15020 2 +Cytochrome complex 0.3922653258304571 0.5188705729830262 0.6038509998502488 1.0 1.0 18 O14548,P20674,P09669,P08574,Q9UDW1,O14949 6 +Pre snornp complex 0.5509628011734146 0.5146004574699444 0.6068322453711918 1.0 1.0 3 O00567 1 +Actomyosin 0.3665461078643424 0.5100415693440891 0.6100223392964867 1.0 1.0 32 Q9Y5S2,Q9UHB6,Q92614,Q9Y613 4 +Myelin sheath abaxonal region 0.4952031185317231 0.5075509643985671 0.6117682865833964 1.0 1.0 4 P05556 1 +Endoplasmic reticulum golgi intermediate compartment 0.2690413617406547 0.507189304310259 0.6120219989485833 1.0 1.0 50 Q99653,Q8N511,Q92614 3 +Spliceosomal complex 0.3981125646168444 0.5054118602244908 0.6132695903768994 1.0 1.0 131 Q9NW64,Q5VTL8,P09234,Q96DF8,Q96I25,Q86V81,P55769,Q9UKA9,Q9UMS4,Q9UNY4,Q8WXA9,P09012,Q15382,O60306,O95391,Q15428,P08621,Q13595,O94906,P52272,Q12972,Q9ULR0,Q9BWJ5,Q96BP3,Q9UNP9,Q92620,Q9P2K5,P62318,P62314,P08579,P62312,Q13435,Q9BZJ0,Q9H2H8,Q9Y3C6,Q9Y312,Q6P2Q9,Q96DI7,P62304,Q15427,Q8WYA6,Q8TBF4,Q9BUQ8,Q8IWZ8,Q9NW13,Q15637,Q8IYB3,Q86UA1 48 +Nuclear pore central transport channel 0.5467599546763964 0.5009304785896732 0.6164200514327995 1.0 1.0 3 Q8NFH5 1 +Fibrillar center 0.2713277147695865 0.4977836439588062 0.618636545434134 1.0 1.0 52 Q12824,Q5GLZ8,P22087,Q15233,O00567,O15446,Q9GZS1,O15160,Q96B26,Q9NZM5,O60832,Q7L014,P08579,P17480,Q96GN5,P78406,Q86UE4,O60264,O95400,Q9H583 20 +Mrna cleavage and polyadenylation specificity factor complex 0.407953476955912 0.4931831737239369 0.6218831659076938 1.0 1.0 8 O43809 1 +Proteasome regulatory particle base subcomplex 0.3919237111272008 0.4898261655877614 0.6242569136041527 1.0 1.0 9 Q99460,P35998,P17980,P62191 4 +Eukaryotic translation initiation factor 3 complex eif3m 0.4058699405392496 0.4849348130476492 0.6277225867189333 1.0 1.0 8 O00303,Q7L2H7,Q13347 3 +Ragulator complex 0.7778112752487152 0.4779222986051845 0.6327055097679397 1.0 1.0 2 Q6IAA8 1 +Mitotic spindle pole 0.3800763418787069 0.4778653807399505 0.632746022919614 1.0 1.0 14 Q96SB8,Q9Y6D9 2 +Intrinsic component of mitochondrial membrane 0.2680955634737892 0.454318931653953 0.649599291900079 1.0 1.0 48 Q8IXI2,Q8IXI1,Q00325,Q9NVH1,Q96ER9,O14925,Q8TB36,Q96NB2,O95140,P12235,O95563,Q8NE86,Q8IWA4,Q9BWH2,Q9Y4W6,Q9BUR5,Q5HYI7,Q9Y512,O75880,O43819,Q6P4A7,O75431,P57105,Q99595,Q53H12,P38646 26 +Mitochondrial protein containing complex 0.4266527844003125 0.4519254641359936 0.6513226792668327 1.0 1.0 158 Q7Z7F7,Q5T653,P05141,P56134,O75438,P50213,O43676,P82914,P48047,Q9Y3D3,P40939,Q96I99,Q567V2,P82912,P30405,Q9UDW1,P10515,P19404,P09669,Q8TCS8,Q8NE86,P08559,P28331,Q8N4H5,Q96CU9,Q96IX5,Q9NS69,O14548,P20674,Q86Y39,Q07812,O75380,P82675,Q8N983,Q5HYI7,P08574,Q9Y2R9,P03915,P55084,O95139,P49406,P82664,Q96RQ3,O95168,O60220,Q9P0J0,Q99595,Q9NX20,Q16795,Q9H2W6,O14949 51 +Cell cell contact zone 0.3749420230365892 0.4514688099422239 0.6516516997163768 1.0 1.0 23 Q9HD47,Q09666,P15924,Q14126,Q9Y613,P41440,P14923 7 +Clathrin coat 0.3767444480282006 0.4509122138009573 0.6520528203100526 1.0 1.0 18 Q9Y6I3,P53680 2 +Phagocytic vesicle membrane 0.3697311723080289 0.4397040379080686 0.6601514776704849 1.0 1.0 25 Q92930,O75396,Q03518,P61006,P10321,P20339,P51809,P04439,Q9BZG1 9 +Intercalated disc 0.3729896412946429 0.439644675621347 0.6601944781384392 1.0 1.0 16 Q14126,Q9HD47,P15924,Q9Y613,P14923 5 +Intrinsic component of mitochondrial outer membrane 0.3700119789217266 0.4360849970478394 0.662775061972507 1.0 1.0 14 Q8IWA4,O95140,Q8IXI1,Q8IXI2,P57105,Q9BWH2,Q8TB36 7 +Phagophore assembly site membrane 0.4367791454689264 0.4325376657157839 0.6653506828924307 1.0 1.0 5 P51149,Q5MNZ6,Q7Z3C6 3 +Cell surface 0.3116831825928491 0.4287239346205729 0.6681241403200979 1.0 1.0 82 Q96JJ7,P17655,Q92614,O15439,Q9NWH9,P14174,Q13740,Q13576,P08195,P41440,P78536 11 +Dendritic spine membrane 0.7585167319867243 0.4270760290932897 0.6693239518209753 1.0 1.0 2 O75787 1 +Golgi associated vesicle 0.3530612012533921 0.4009243659879775 0.6884758099443353 1.0 1.0 29 Q92930,Q8TCT8,Q8N511 3 +Cortical cytoskeleton 0.2777478972101732 0.3804345932161249 0.7036228398822606 1.0 1.0 45 P41440,O15020 2 +Ap type membrane coat adaptor complex 0.3477792228814349 0.3784823760131072 0.7050722836791445 1.0 1.0 10 O95782,P53680 2 +Mrna cleavage factor complex 0.3493022141752628 0.3757701463666671 0.7070877837130245 1.0 1.0 11 O43809 1 +U7 snrnp 0.7374133252939401 0.3743781151367807 0.7081230226666293 1.0 1.0 2 P62318 1 +Smn sm protein complex 0.3462291277810185 0.3727501852919347 0.7093343813869633 1.0 1.0 10 P62304,P62318,P62314,P57678 4 +Multimeric ribonuclease p complex 0.7359059391015946 0.370737959897134 0.7108327140702619 1.0 1.0 2 Q99575 1 +Nucleolar ribonuclease p complex 0.7359059391015946 0.370737959897134 0.7108327140702619 1.0 1.0 2 Q99575 1 +Integral component of synaptic vesicle membrane 0.4532396115010546 0.3699226396153964 0.7114401321863317 1.0 1.0 4 Q86Y82 1 +Respiratory chain complex iii 0.3746604786447473 0.3684157656449168 0.7125632436232583 1.0 1.0 8 P14927,Q9UDW1,P08574,O14949 4 +Ciliary tip 0.3595072498000078 0.3656404406654908 0.7146333943209517 1.0 1.0 9 A0AVF1,Q13099,P63167,Q96FJ2,Q9Y496 5 +Site of double strand break 0.3392355212753795 0.3635737538214051 0.7161763287735265 1.0 1.0 31 O94874,Q9BUR4,P61160,P09874,P59998,Q9H4L7,Q9NW82,O15144,O60934,Q96SB8,Q9UMS4,P16104,Q68E01,A6NHR9 14 +Tim23 mitochondrial import inner membrane translocase complex 0.4161108333275436 0.3628768258838057 0.7166968987605857 1.0 1.0 5 Q99595 1 +Rna polymerase ii transcription regulator complex 0.3378057016497507 0.3574584257877801 0.7207486443988089 1.0 1.0 31 Q13503,Q9ULK4,O60244,P13984,P17096,Q8N3C0 6 +Phagophore assembly site 0.3706953915037796 0.3546555613199497 0.7228476463882929 1.0 1.0 8 P51149,Q5MNZ6,Q7Z3C6,Q86Y82,Q8NEB9 5 +90s preribosome 0.3484153480219011 0.3504641705369343 0.7259903749296208 1.0 1.0 25 Q14137,O00541,Q12788,Q8TCT8,Q9H583,O76021 6 +Spindle midzone 0.3509922938421109 0.3477266034165114 0.7280455153819856 1.0 1.0 19 Q9NVJ2,P60953,Q9NQS7,Q7Z7K6 4 +Postsynaptic density membrane 0.3811745565610367 0.3447705187416076 0.7302668983081517 1.0 1.0 7 Q99720 1 +Inclusion body 0.3385057213162953 0.3394175968087903 0.7342951642197761 1.0 1.0 29 O14641 1 +Histone deacetylase complex 0.345879419006396 0.3363130640729444 0.7366347994138867 1.0 1.0 24 Q92769,Q13330,Q14839,Q9UBU8,Q9GZN1,Q96ST3,O94776,Q9BZK7,Q6ZRS2,Q16576,Q9NPF5 11 +Proton transporting two sector atpase complex catalytic domain 0.3367770321731869 0.3309260726257704 0.740700327400655 1.0 1.0 11 Q9Y5K8,P21283 2 +Caveola 0.3438585392307576 0.3283487268959328 0.7426480057544678 1.0 1.0 16 P41440 1 +Protein phosphatase type 1 complex 0.4877748080734492 0.3250226361068697 0.7451639398529362 1.0 1.0 3 P62140 1 +Lamellipodium 0.2706099200353573 0.3169557360152156 0.7512771893693144 1.0 1.0 68 Q8N8S7,Q9Y5S2,Q9UHY1,P31749,Q13576,P51153,P41440 7 +Atpase complex 0.2780067199088709 0.316871782912746 0.7513408935263874 1.0 1.0 43 Q12824,Q92769,P28370,Q9NR30,Q13330,Q14839,O60264,Q9NY93,Q9GZN1,Q8TAQ2,O94776,Q96T23,Q6ZRS2,Q15257,Q9NPF5,Q9BQG0 16 +M band 0.4846828055011091 0.3167426644814592 0.7514388727344388 1.0 1.0 3 P06733 1 +Proton transporting two sector atpase complex 0.3403510476881845 0.3129287135007974 0.7543348221299044 1.0 1.0 23 P56134,P21283,Q96IX5,Q9Y5K8,Q8N511,O75787 6 +Presynaptic active zone 0.336689905426261 0.3038845123211746 0.761215877538308 1.0 1.0 16 P41440 1 +Specific granule membrane 0.3323431534050987 0.2896556899930231 0.7720796579370566 1.0 1.0 16 Q9Y2Q5,Q6IAA8,Q14165,Q08722,Q9Y5K8,O60784 6 +Nuclear lamina 0.3919734459867171 0.2884184914201949 0.7730264147437236 1.0 1.0 5 P56537,P02545,P12004,P20700 4 +Endoplasmic reticulum chaperone complex 0.3495353360320837 0.285751935405486 0.7750681236846091 1.0 1.0 8 Q15084,Q8IXB1,Q9HCN8,P23284 4 +Cell projection membrane 0.2619565387118462 0.2804604563468394 0.7791242597691126 1.0 1.0 67 Q9HCM4,Q9UHB6,Q15286,P62330,O15144,O75122,Q9BZG1,P41440,P78536,O75787 10 +Proteasome regulatory particle lid subcomplex 0.3608364591547871 0.2802142694352437 0.779313119613745 1.0 1.0 7 O00487,Q16186 2 +Intrinsic component of mitochondrial inner membrane 0.3142913376993507 0.2761134893323098 0.7824609002783645 1.0 1.0 32 O75880,Q96NB2,Q00325,O43819,Q6P4A7,Q9NVH1,O95563,Q96ER9,Q8NE86,Q99595,O14925,Q5HYI7,Q53H12 13 +Ruffle 0.25278519842301 0.2741668377993181 0.7839564116165656 1.0 1.0 62 Q9HCM4,Q9UHB6,P53365,P62330,P20339,O75122,Q9BZG1,P78536 8 +Cytoplasmic microtubule 0.3259499728573745 0.2631702229293353 0.7924193807143995 1.0 1.0 22 Q9H6H4,O75122 2 +Golgi apparatus subcompartment 0.2960174666107545 0.2623256272415298 0.793070405959555 1.0 1.0 92 Q92614,P53365,Q7Z6M1,P61006,Q9BXS4,Q9H9E3,Q96JB2,Q99996,O60568,P51153,O14828,Q16706,Q96A57,Q7Z3C6,Q10567,O43795,O75122,P04439,Q9BZG1,P28838,Q99700,Q9NX62,Q99986 23 +Endoplasmic reticulum exit site 0.3241106870044829 0.2611740907029116 0.7939582575060389 1.0 1.0 17 O75340,Q5JRA6,O95486,Q9P0L0,Q9HCU5,P04439 6 +Mitochondrion 0.2509374089154326 0.2559326470995541 0.798002845194318 1.0 1.0 635 Q7Z7F7,Q5T653,Q8N2F6,P05141,P00505,P50213,P82914,Q9H6K4,P48047,Q969Y2,Q16775,Q8NHU6,Q9NPL8,Q9BYD6,Q8NI60,Q9UGM6,Q9UJZ1,Q9NYY8,Q07021,O15446,P31689,Q8IUX1,Q9BQ95,O14548,Q9BQP7,Q9BUT1,P17655,Q9BW92,Q9BYT8,Q9HCN4,Q9NR30,Q8TD30,Q9Y320,Q9BRT2,Q07812,Q7Z3C6,O00116,P31749,P82675,Q8N983,Q5HYI7,P08574,O75127,P03915,Q5TC12,Q86Y07,P55084,P36957,P05165,P23786,P22033,Q96BK5,Q96RQ3,Q5ST30,P35613,Q9NX47,Q9HCL2,Q9NVT9,Q9NX20,Q9BSK2,Q9P2R7,Q16795,Q9UIJ7,O75438,P09874,Q9H3P7,P38117,P11498,Q6P587,Q9Y3D3,P40939,Q9H2U2,Q99798,Q96I99,P82912,Q8TB36,Q6FI81,Q8IYB8,Q7L8L6,Q6UB35,Q96NB2,P09669,O95140,Q9Y3D9,Q99797,Q9NQH7,Q9NRA0,Q9H2V7,Q9UBF8,Q8NE86,O95202,Q96IX5,P14927,Q5T160,P30048,P55809,P52758,P53701,P09622,Q9Y2S7,Q9BSH4,Q86Y39,Q16539,P42126,Q9Y2Q3,Q9H974,O95139,O15382,Q969Z0,Q00059,Q9Y237,Q9NUL7,Q9H2W6,O43676,Q00325,Q9NY93,Q567V2,P30405,P30038,Q8TCS8,Q8WTT2,Q07820,O95563,O75616,P08559,P28331,Q9BW91,Q96CU9,Q9UMS0,Q9NS69,Q15031,O75380,P49406,O43819,O60333,O95168,P04179,O60220,P22570,Q9H583,Q9P0J0,Q9UII2,P56134,P22830,Q8NFV4,Q96ER9,Q9UDW1,P10515,P19404,P26440,Q02218,Q96A26,Q96EY7,Q9H078,Q9NP81,Q8N4H5,Q92947,Q5T440,P20674,Q4G176,Q15120,Q9UNQ2,Q9Y2R9,P23368,P25325,P82664,Q96RP9,Q6P4A7,Q7LG56,Q8TBP6,Q92665,Q9Y3E5,Q99595,Q9UMY1,O14949 175 +Phagocytic vesicle 0.2532687670978593 0.2555292963261116 0.798314319255788 1.0 1.0 45 Q92930,O00159,O75396,Q03518,P61006,P10321,P50995,Q86Y82,P20339,P51809,P60953,P04439,Q9BZG1 13 +Chaperonin containing t complex 0.3349441256417947 0.2430249653604612 0.8079860575498132 1.0 1.0 8 Q99832,P48643,P40227,P78371,P49368,P50990,P17987 7 +Catalytic complex 0.1923335141512111 0.2281074817814062 0.81956268379627 1.0 1.0 537 Q96T37,P50213,Q86V81,Q9GZZ1,P41440,Q15022,Q00403,O15446,O95391,Q15428,O94906,P52272,Q96B26,Q9NPF5,Q9NWU2,P17655,Q13868,Q9NR30,Q96BP3,Q9UNP9,Q99547,P08574,P08579,P03915,P46977,P36957,P05165,Q99575,Q96RQ3,Q14165,Q96QC0,Q9BZK7,Q9BUQ8,Q9NZL9,Q9P2R7,Q16795,Q9NW64,A1L0T0,O75438,P24928,P38117,Q96I99,Q8NEB9,Q8IYB8,Q96S52,O15160,Q9GZS1,Q9Y4W2,Q9UBU8,Q9Y285,Q9ULR0,O00487,Q96SB8,P08069,P14927,P09622,Q9Y2S7,Q13330,Q86Y39,Q14839,Q14344,Q15291,P62318,P62314,Q6UXN9,Q92541,Q96FJ2,Q9H9Y6,Q9H974,Q9Y2L1,Q9ULM3,P62140,P61962,Q9UNM6,O95139,Q6P2Q9,Q96DI7,O43396,O60264,O95602,P39656,Q969N2,Q12824,P04844,O43676,Q9NY93,Q9H871,Q9GZN1,O75340,Q8TCS8,Q8NFC6,P08559,P28331,Q96CU9,Q8N5L8,P13984,O75380,Q9HAF1,Q9BZJ0,Q9H2H8,Q9UJA5,Q9Y3C6,Q5RKV6,O95168,Q16186,Q9P0J0,Q96ST3,Q96T23,Q9UDW1,Q5VZE5,O60762,P10515,P19404,Q02218,Q9BUN8,O60832,P62875,Q92620,Q05086,P35251,Q06265,O14949 122 +Lateral plasma membrane 0.3131042346845195 0.225191250446059 0.821830495791108 1.0 1.0 21 O14641 1 +Cornified envelope 0.3530924306653789 0.2237221607486607 0.8229735011932895 1.0 1.0 6 P14923,Q14126 2 +Plasma membrane raft 0.3120310462759026 0.2222906240878979 0.8240876504285319 1.0 1.0 21 P41440 1 +Tim22 mitochondrial import inner membrane insertion complex 0.6647573108230287 0.2199642040933025 0.8258990329345743 1.0 1.0 2 Q53H12 1 +Methyltransferase complex 0.2684749626794896 0.2173080893848862 0.8279682533060821 1.0 1.0 40 Q9Y4W2,Q96T37,P62314,Q8NFC6 4 +Nuclear protein containing complex 0.2297548387751742 0.2168020453403092 0.8283626179195158 1.0 1.0 497 O60244,Q86V81,P55769,Q8N3C0,Q9Y3Y2,Q9NVH2,Q15382,Q86W42,Q15022,P43487,Q00403,O15446,O95391,Q15428,P08621,Q8TCT8,O94906,P52272,Q96B26,Q9BWJ5,Q5SRE5,Q9NPF5,Q13868,Q9NR30,Q96BP3,Q9UNP9,O60216,P62312,P08579,Q99575,Q15427,Q8WYA6,Q8TBF4,Q9BZK7,Q9BUQ8,Q9NW13,Q9UH99,Q9NW64,Q14137,Q13503,O00541,P24928,O43633,P37198,Q15554,P49790,Q7L590,Q8WXA9,Q8WX92,Q9ULK4,O15160,Q9GZS1,Q9Y4W2,Q9UBU8,Q12972,Q9ULR0,P57678,P14923,Q9Y2S7,Q13330,Q14839,Q15291,P62318,P62314,Q6UXN9,Q92541,Q9H9Y6,Q9H444,Q9Y2L1,Q9ULM3,Q6P2Q9,Q96DI7,O60264,O95400,Q8NFH5,Q8IWZ8,O95602,P62487,Q9BQG0,Q8TEM1,Q12824,Q9HAU5,Q9UQR0,Q9NY93,Q9GZN1,Q9UKA9,Q15233,Q9UMS4,Q9UNY4,P09012,O94901,O60306,P28370,Q8NFC6,P33992,Q8N201,P82979,O60934,Q96CB8,Q9BTX1,Q15185,Q9BUR4,O43809,P13984,Q9P2K5,Q9HAF1,Q13435,Q9BZJ0,Q9H2H8,Q9Y3C6,P18887,P62304,Q5RKV6,P19388,P78346,P17096,P28340,P49005,Q8NI36,Q8NI27,Q9H583,Q8IYB3,Q86UA1,Q9Y6D9,Q5VTL8,Q92769,P09234,Q96DF8,Q96I25,Q9UJX4,Q96ST3,Q96T23,Q9H0A0,O75643,O00159,P19387,P49642,Q13595,P34897,Q8TAQ2,Q6ZRS2,Q68E01,Q13523,P33240,Q13185,O60832,Q9Y5B9,Q96RS0,P62875,Q92620,P78406,Q9Y312,Q15637,Q06265 154 +Envelope 0.2237309005104974 0.2159552715460151 0.829022612978759 1.0 1.0 494 Q7Z7F7,Q96T37,Q5T653,P05141,P82914,P48047,Q9NPL8,Q9BYD6,Q8NI60,Q9UI26,Q9UJZ1,P43487,Q8IUX1,P50995,Q5SRE5,Q8N2G8,Q9BQ95,O14548,P17655,Q9BYT8,Q9Y320,Q9BRT2,Q07812,P82675,Q8N983,Q5HYI7,P08574,P03915,P57088,Q86Y07,P55084,Q99720,P23786,Q86UE4,Q9NX47,Q9HCL2,Q9NVT9,Q9NX20,Q9BVC6,Q9BSK2,Q9UH99,Q16795,O75438,P04406,P09874,O43633,P37198,Q9Y3D3,P49790,P40939,P82912,Q8TB36,Q6FI81,Q96NB2,P09669,O95140,Q9Y3D9,Q9NRA0,Q9H2V7,Q9UBF8,Q8NE86,Q96IX5,Q86Y39,Q7Z7K6,Q9H974,Q15125,O95139,Q8NFH5,Q9H2W6,O43676,Q00325,Q5JTV8,Q567V2,P30405,O94901,Q8TCS8,Q8N201,Q07820,O95563,O75616,P28331,Q9BW91,Q96C57,Q96CU9,Q9BTX1,Q9NS69,O75380,P49406,O43819,O95168,O60220,P22570,Q9P0J0,Q9Y6D9,P56134,P22830,Q96ER9,Q9UDW1,O00159,P19404,Q02218,Q96A26,Q96EY7,Q9H078,Q8N4H5,P20674,Q9Y2R9,Q9Y5Q9,Q9BZE4,P78406,P82664,Q6P4A7,Q8TBP6,Q92665,Q99595,O14949 116 +Basolateral plasma membrane 0.2717381206785159 0.2140974767835681 0.830471043414652 1.0 1.0 39 O15439,P35613,Q9BY67,P08195,P41440 5 +Microvillus 0.3081940804135775 0.2124590561745933 0.8317489170390522 1.0 1.0 20 O00159,P35241,Q7Z4W1,Q6P1M0,Q96A65,Q13576,O43795,P36543,P35222 9 +Pigment granule 0.2368670441922501 0.2121586940843848 0.8319832305077626 1.0 1.0 61 Q15286,P51148,P35613,P62820,P20339,P54709,P61019,P08195,P41440 9 +Endoplasmic reticulum 0.2230966428677033 0.2117237115809482 0.8323225882749763 1.0 1.0 479 Q969N2,Q8NBJ5,Q8N2F6,P04844,Q02878,P62857,Q5VV42,Q9BU23,Q8N5M9,Q13724,Q8N511,Q15382,O75787,Q96JJ7,O75340,O43909,P11047,Q96S52,Q6ZXV5,Q86XL3,Q8TCS8,Q99653,Q8TCT8,Q9Y394,Q9UBF8,Q9BRK5,O60568,P42858,P60953,Q9H6H4,Q8N2G8,Q8TB61,Q96A57,P17655,Q03518,Q92604,Q9HD47,P61353,P82094,P62847,Q6NUK4,P55145,P78536,Q86Y07,Q15125,Q99720,P26885,Q14165,Q9Y673,P35613,Q9NX47,Q9BVC6,P62820,Q8NBQ5 54 +Sarcoplasm 0.307043733177457 0.2103716417770158 0.8333776239906532 1.0 1.0 19 P55145 1 +Chromosome 0.202706291140497 0.2089047810052846 0.8345225718057878 1.0 1.0 469 O15164,Q86V81,Q8WVJ2,Q9NVH2,P41440,Q86W42,Q15022,Q00403,O15446,P51608,Q8TDN6,P46013,Q96B26,Q9NPF5,P07305,P42696,P17655,Q9Y4C8,Q99848,P05114,Q15435,P54132,Q96BK5,Q969T9,Q96QC0,Q49A26,P16403,Q15554,Q7L590,P62805,P10412,Q9NZM5,Q96SB8,Q9Y2S7,Q2NKX8,O75122,Q7Z7K6,Q9H9Y6,Q9H7B2,P62140,P46100,Q9P0M6,Q96GQ7,P50748,O75683,Q8IY81,Q9Y237,O75367,Q12824,Q9NY93,Q9GZN1,Q96L73,Q5SSJ5,Q8NFC6,Q9ULX6,Q13610,O15144,O60934,Q92522,Q9HAF1,Q9NQS7,P0CG13,P17096,Q8NI27,Q9Y6D9,Q53HL2,P16402,Q7Z6E9,Q96ST3,Q96T23,Q9H0A0,Q9H0U9,Q9NVP1,Q71F23,P42771,Q96KR1,O76021,Q14684,Q9BYG3,Q9HBM1,P05204,P35251,P80723,Q02880,Q9UMY1,Q13895,Q06265 87 +Fascia adherens 0.3446503491209238 0.2018805610933337 0.8400100991868054 1.0 1.0 6 P35222,P14923,P15924 3 +Ribonucleoprotein complex 0.4137584459357589 0.2001859337003319 0.8413351677962151 1.0 1.0 438 Q7Z7F7,Q5T653,P22087,P61513,Q86V81,P82914,P55769,Q2NL82,Q68CQ4,P62857,Q9BYD6,Q15382,O95391,Q15428,P08621,Q8TCT8,O94906,P52272,P46776,P62081,Q7Z478,Q9BWJ5,Q92879,Q12905,Q96BP3,Q9UNP9,Q99848,O15213,P62847,P82675,Q8N983,P62312,P08579,O43347,Q99575,P47914,Q15427,Q8WYA6,Q8TBF4,Q9BUQ8,Q9NW13,Q9NX20,P62244,Q9NW64,Q14137,Q9BSC4,O00541,P04406,P18077,Q9Y3U8,P37198,P50914,P62701,P62280,Q9Y3D3,P39019,Q8WXA9,P82912,Q9NQ55,Q9Y4W2,Q9UN86,Q12972,Q9ULR0,P57678,P61247,P61353,P62318,P62314,P84098,Q6P2Q9,Q96DI7,Q9Y3A2,O95400,Q8IWZ8,P61011,P61313,Q12906,Q8IY81,Q8N5N7,Q9H2W6,Q8NEF9,Q8IXT5,Q7L2H7,Q02878,P62424,Q9BVJ6,Q9HAU5,Q9UKA9,Q9UMS4,Q9UNY4,Q86U42,Q567V2,P09012,O00567,O60306,P08708,P11388,Q8TCS8,P30050,Q9ULX6,Q13601,Q13347,P62854,P62753,P62266,Q9BTD8,Q15185,Q9BUR4,Q8N5L8,Q9BXY0,O95478,P36578,Q9P2K5,P62910,P83881,P62899,Q14690,Q13435,Q9BZJ0,Q9H2H8,Q9Y3C6,P49406,Q6DKI1,P62304,P78346,Q8NI36,Q969S3,Q9H583,Q8IYB3,Q86UA1,Q5VTL8,P83731,P09234,Q96DF8,Q96I25,P62269,P62750,P62841,Q12789,Q6P1L8,Q9H0A0,O15091,O75643,O75821,P06748,P09001,P62277,Q12849,Q13595,P51398,P46777,P40429,Q02543,Q13523,O60832,O76021,P26373,Q96RS0,P63173,Q12788,Q9UKM9,Q14684,Q92620,Q9BY44,Q9Y2R5,Q9Y3B7,Q00839,P18124,Q9Y2R9,P15880,P39023,P32969,P60866,P62917,P82664,Q02880,Q99700,Q9H9Y2,Q9Y312,Q13895,Q15637 181 +Nucleolus 0.3692556122684758 0.2001766902807396 0.8413423966773528 1.0 1.0 438 P22087,P82914,P55769,Q2NL82,Q68CQ4,Q9Y3Y2,P41440,Q9Y3A5,Q15022,Q07021,Q9NVU7,O15446,Q8TCT8,P46087,Q8NHQ9,P52272,P62081,Q8TDN6,P46013,Q96B26,Q9BQ39,P42696,O14548,Q1ED39,Q13868,Q9NR30,Q12905,Q9Y4C8,Q99848,O00116,O15213,Q99547,P62312,P08579,P17480,P23786,P54132,Q99575,Q96BK5,Q7L5D6,Q86UE4,Q96DE0,Q96IU4,Q9BUQ8,Q9NW13,Q9UIJ7,Q14137,Q9BSC4,O00541,O15226,P09874,Q9Y3U8,P24928,P62280,P49790,Q9NX58,Q9H501,P39019,Q7L590,Q6FI81,O15160,Q9GZS1,Q9NQ55,Q9Y4W2,Q9H2V7,Q8TDD1,Q66K74,O43709,P57678,Q9NZM5,Q9H6R0,O95347,P61247,Q15291,P61353,O43324,Q6UXN9,Q92541,Q9H9Y6,Q9H7B2,Q9GZR2,Q9Y2L1,P84098,P62140,Q96GQ7,O60264,Q9Y3A2,P25685,O95400,O95602,P61011,Q12906,O75683,Q8IY81,Q9Y237,Q9NUL7,Q9BQG0,Q99986,O75367,Q12824,Q5GLZ8,P62424,Q9BVJ6,Q9ULW3,Q9NY93,Q15233,Q9UHA3,O00567,P11388,P30050,Q8WTT2,Q13610,Q13601,O60934,P08559,P62753,P62136,Q92522,Q7L014,Q9BV44,Q9BXY0,Q9H6W3,O95478,P36578,Q9HAF1,Q96GN5,Q6DKI1,Q5RKV6,Q969S3,Q9H9L3,Q9H583,Q53HL2,P62750,Q12789,Q99584,Q7Z6E9,Q96ST3,Q9H0A0,Q9H0U9,Q9NVP1,O00159,P62277,Q13595,Q13823,Q99590,O60832,O76021,P26373,P62875,Q12788,Q14684,Q15120,Q9BYG3,Q9H0S4,Q9UNQ2,Q9Y2P8,Q9Y5Q9,Q9BZE4,P35251,P39023,P78406,Q02880,Q92665,Q9H9Y2,Q9UMY1,Q13895,Q14527,Q06265 168 +Filopodium 0.2893415000699946 0.1984531958101857 0.8426905007354533 1.0 1.0 32 Q8N8S7,P62330,Q13576 3 +Organelle subcompartment 0.2818308255853566 0.1805224831887791 0.8567424053024586 1.0 1.0 368 Q8N2F6,Q92614,P53365,Q7Z6M1,P61006,P62857,Q9BU23,Q9NTJ5,Q8N511,Q15382,Q96JJ7,O43909,Q96JB2,Q8TCT8,P31689,P48651,O60568,Q9H6H4,Q96A57,Q92604,Q9Y320,Q7Z3C6,Q07812,P10321,O43795,O75477,P04439,P46977,P57088,Q86Y07,Q99720,P28838,P26885,Q5JRA6,Q14165,Q86UE4,P35613,Q9BT22,Q9NX47,Q9HCU5,Q9NX62,Q9BVC6,Q14534,A1L0T0,O95486,Q9BXS4,P61586,Q8N5M9,Q96S52,Q9Y394,Q9UBF8,P60953,P51153,Q8TB61,Q16706,Q03518,P61353,O75122,Q6NUK4,Q15125,Q9Y673,Q99986,Q969N2,P04844,Q5VV42,Q13724,O75787,O75340,Q86XL3,Q8TCS8,Q9NP72,O14828,P78356,Q9BZG1,O60725,P61019,Q9H9E3,O60762,O75396,Q99996,Q9BUN8,Q10567,Q9P2E9,P60468,Q99700,Q9P0I2,Q04323 87 +Transcription repressor complex 0.2917322375963208 0.1800701522032912 0.8570974946491581 1.0 1.0 16 P07305 1 +Proteasome regulatory particle 0.291919955858643 0.1764884060188002 0.859910256376057 1.0 1.0 18 Q9UNM6,P35998,P17980,Q99460,O43242,P51665,Q16186,O00487,P62191 9 +Lamellar body 0.6367199276454584 0.1728471916697406 0.8627715416781045 1.0 1.0 2 P51149 1 +Proton transporting v type atpase v1 domain 0.3186915053850433 0.1694919813829915 0.8654096790453503 1.0 1.0 7 Q9UI12,Q9Y5K8,P21283 3 +Non motile cilium 0.2861879531588417 0.1663673596712432 0.8678678591677489 1.0 1.0 17 P35613 1 +Mitochondrial envelope 0.2993781398498205 0.1659678591522041 0.8681822440164084 1.0 1.0 316 Q7Z7F7,Q5T653,P05141,P82914,P48047,Q9NPL8,Q9BYD6,Q8NI60,Q9UJZ1,Q8IUX1,Q9BQ95,O14548,P17655,Q9BYT8,Q9Y320,Q9BRT2,Q07812,P82675,Q8N983,Q5HYI7,P08574,P03915,Q86Y07,P55084,P23786,Q9NX47,Q9HCL2,Q9NVT9,Q9NX20,Q9BSK2,Q16795,O75438,Q9Y3D3,P40939,P82912,Q8TB36,Q6FI81,Q96NB2,P09669,O95140,Q9Y3D9,Q9NRA0,Q9H2V7,Q9UBF8,Q8NE86,O95202,Q96IX5,P14927,Q86Y39,Q9H974,O95139,Q9H2W6,O43676,Q00325,Q567V2,P30405,Q8TCS8,Q07820,O95563,O75616,P28331,Q96CU9,Q9NS69,O75380,P49406,O43819,O95168,O60220,P22570,Q9P0J0,P56134,P22830,Q96ER9,Q9UDW1,P19404,Q02218,Q96A26,Q96EY7,Q9H078,Q8N4H5,P20674,Q9Y2R9,P82664,Q6P4A7,Q8TBP6,Q92665,Q99595,O14949 88 +Nuclear body 0.3181515460583141 0.165688942871616 0.8684017480880859 1.0 1.0 315 Q96T37,P04844,P09234,O75438,P22087,Q86V81,O14641,Q15554,Q7Z6E9,Q8N3C0,Q9Y3Y2,Q5SSJ5,Q9BY77,Q9NVH2,Q86W42,O75695,Q13247,O00159,Q15022,Q00403,O95391,Q15428,Q8WTT2,Q9ULX6,P08621,O94906,P49750,Q9UBW7,Q8TF01,Q99590,O60934,Q12972,P52272,P46013,Q9BW91,Q8N9N2,Q9BPY3,Q96SB8,P07305,P33240,Q9NPF4,O60832,Q14151,Q96BP3,Q9Y4C8,O43809,Q9NWH9,Q9BRT2,Q16539,Q9P2N5,Q9BZJ0,Q9GZR2,Q9NQS7,Q92930,P61962,P46100,P54132,P80723,Q96DI7,Q86XP3,O95400,Q96QC0,Q6P6C2,Q8NI27,Q15637,Q9UIJ7 66 +Vesicle coat 0.2808995910360666 0.1642819709938064 0.8695091739260252 1.0 1.0 29 Q9Y6I3,P53680 2 +Exocyst 0.3024137044550821 0.163165745789526 0.8703879356322282 1.0 1.0 8 Q9Y2D4 1 +Condensed nuclear chromosome 0.2856677900410706 0.1627397685353743 0.8707233336000144 1.0 1.0 24 P18754,P54132,Q9BYG3,Q92878,O60216,P16104,Q15050,P42704,Q14683,Q9NQS7 10 +Nuclear outer membrane endoplasmic reticulum membrane network 0.2601510163021094 0.1614965974617143 0.8717022910156034 1.0 1.0 300 Q969N2,Q8N2F6,P04844,P62857,Q5VV42,Q8N5M9,Q9BU23,Q13724,Q8N511,Q15382,O75787,Q96JJ7,O75340,O43909,Q96S52,Q86XL3,Q8TCS8,Q8TCT8,Q9Y394,Q9UBF8,O60568,P60953,Q9H6H4,Q8TB61,Q03518,Q92604,P61353,Q6NUK4,Q86Y07,Q15125,Q99720,P26885,Q14165,Q9Y673,P35613,Q9NX47,Q9BVC6 37 +Membrane protein complex 0.1983324554753442 0.1606586122476822 0.8723622885356022 1.0 1.0 297 Q969N2,P05141,P21283,P04844,O75438,O43676,P56134,Q9UMY4,P42574,Q09666,Q96ER9,P30405,P41440,Q8N511,O94901,O75787,Q9UDW1,O75340,O75396,Q96S52,P09669,Q9Y6I3,P19404,Q99996,Q8NE86,Q9BUN8,P28331,Q8N4H5,Q96CU9,Q5VZ89,Q96IX5,Q9NS69,O14548,P20674,Q03518,Q86Y39,P53680,O75380,Q5HYI7,P03915,P60468,Q9UBC2,O95139,Q14165,Q6IAA8,O95168,Q86Y82,Q9Y5K8,P54709,Q99595,Q9P0I2,P08195,Q9P0J0,Q04323,O14949 55 +Membrane microdomain 0.2276854258862442 0.1577105463289508 0.8746848897340664 1.0 1.0 67 O00159,P05141,P17655,Q9HD47,P42574,Q6IAA8,Q09666,P35613,Q86Y82,P20339,P41440,P78536 12 +Desmosome 0.312378645192898 0.1558084480549748 0.8761840113719923 1.0 1.0 7 P14923,Q14126 2 +Centriolar satellite 0.2780327277389756 0.1555525795055931 0.8763857058902993 1.0 1.0 28 O43809,Q9Y5A9,P41440,Q03518 4 +Mhc protein complex 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 1.0 3 P10321 1 +Mhc class i protein complex 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 1.0 3 P10321 1 +Transcription regulator complex 0.2405608697819524 0.1554699556721941 0.8764508378231384 1.0 1.0 77 Q13503,Q00403,Q9ULK4,O15446,Q13330,P09874,O60244,P13984,Q12789,P17096,Q9Y5Q8,Q8N3C0,Q9BZK7,Q96ST3,Q9Y5Q9,Q8N9N2,Q8WUA4,P07305 18 +Neurofilament 0.3670524517198517 0.153577960114436 0.8779425160273595 1.0 1.0 4 Q5SW96 1 +Pinosome 0.6237564063913096 0.1535326140624107 0.8779782728878041 1.0 1.0 2 Q9UKG1 1 +Synapse 0.1945701160764216 0.1511692169258682 0.8798422325357551 1.0 1.0 263 P83731,Q02878,Q15286,P61006,P62269,P62841,P40123,P50914,P62701,P61586,P51809,P46939,O15020,P41440,Q15382,O75787,P20338,Q07021,P11047,P62277,Q99996,P51608,Q8TF01,O15144,P62081,P60953,Q96CX2,P42858,P51153,Q8N9N2,O43760,Q8N8S7,Q96A57,P63173,P35080,Q13492,Q16539,Q01970,P31749,P20339,Q02952,Q9BY67,P25325,Q92930,Q99720,P84098,Q9NVJ2,P39023,P60866,P62917,P62330,O60333,Q86Y82,P08195 54 +Cell leading edge 0.2967723906039152 0.149732636043689 0.8809755585960608 1.0 1.0 124 Q8N8S7,Q9HCM4,Q9UHB6,P53365,Q9Y5S2,P62330,Q9UHY1,Q86TI2,O15144,P31749,P20339,Q13576,P60953,P51153,O75122,P41440,P78536,O75787 18 +Lamin filament 0.408624849215922 0.1493170726270865 0.8813034442819936 1.0 1.0 3 P56537,P20700 2 +Anchoring junction 0.2436413275701032 0.149217257635753 0.8813822028198817 1.0 1.0 256 O43491,Q9HCM4,Q02878,P62424,P61513,P62269,P62841,Q09666,P62701,P62280,Q13740,P61586,Q9Y624,O15020,P39019,Q14126,P41440,O15143,Q99797,P62277,Q99653,Q9Y5S2,Q9P0L0,O15144,P62081,P60953,P51153,Q9UBG0,Q14676,P14923,Q8N8S7,P35241,Q9UHB6,P17655,P63173,Q9Y2S7,Q9HD47,Q9UHD1,P61247,P61160,Q16513,P61353,P36578,P31749,P16989,O75122,Q02952,P62899,Q13308,Q9BY67,P78536,P84098,P62140,P28838,P39023,P32969,O75083,Q9UGI8,P62917,Q86UE4,P62330,P35613,P17096,Q9H8V3,Q9Y613 65 +Zona pellucida receptor complex 0.334640917320453 0.1472535540854522 0.8829318912209856 1.0 1.0 5 P78371,P49368,P50990,P17987 4 +Mitochondrial matrix 0.357034924106911 0.1469271811587955 0.8831894972836773 1.0 1.0 244 Q7Z7F7,Q5T653,P05141,P00505,P50213,P82914,Q16775,Q8NHU6,Q9UGM6,Q9NYY8,Q07021,Q9BW92,Q8TD30,Q9BRT2,P82675,Q8N983,O75127,P55084,P36957,P05165,P22033,Q96RQ3,Q9NX20,Q9P2R7,Q16795,Q9UIJ7,P38117,P11498,Q6P587,Q9Y3D3,P40939,Q9H2U2,Q96I99,Q99798,P82912,Q8IYB8,Q6UB35,Q7L8L6,Q99797,Q5T160,P30048,P55809,P52758,P09622,Q9Y2S7,Q4G0N4,P42126,Q9Y2Q3,O15382,Q969Z0,Q00059,Q9Y237,Q9NUL7,Q9H2W6,Q567V2,P30405,P30038,Q8TCS8,O75616,P08559,P28331,Q9BW91,Q15031,P49406,O43819,P04179,P22570,P22830,P10515,P26440,Q02218,Q9NP81,Q92947,Q5T440,Q4G176,Q15120,Q9UNQ2,Q9Y2R9,P23368,P25325,P82664,Q96RP9 82 +Organelle inner membrane 0.3603190233870638 0.1465195337777464 0.8835112705988071 1.0 1.0 241 Q7Z7F7,Q5T653,P05141,P82914,P48047,Q9NPL8,Q9BYD6,Q8NI60,Q9UJZ1,Q8IUX1,Q9BQ95,O14548,Q9BRT2,P82675,Q8N983,Q5HYI7,P08574,P03915,P55084,Q99720,P23786,Q9NX20,Q9BSK2,Q9UH99,Q16795,O75438,Q9Y3D3,P40939,P82912,Q96NB2,P09669,Q9Y3D9,Q9NRA0,Q9H2V7,Q8NE86,O95202,Q96IX5,P14927,P53701,Q86Y39,Q9H845,O95139,Q69YU5,P12532,Q53H12,Q8N5N7,Q9H2W6,Q5SNT2,O43676,Q00325,Q5JTV8,Q567V2,O94901,O95563,O75616,P28331,Q96CU9,O75380,P49406,O43819,O95168,O60220,P22570,Q9P0J0,P56134,P22830,Q96ER9,Q9UDW1,P19404,Q96EY7,P20674,Q9Y2R9,P82664,Q6P4A7,Q8TBP6,Q92665,Q99595,O14949 78 +Intrinsic component of nuclear inner membrane 0.3074257169495991 0.1456191629656475 0.8842220393830502 1.0 1.0 7 Q9UH99,Q5SNT2,O94901 3 +Presynapse 0.2593745604004295 0.1442543309420307 0.8852996396593369 1.0 1.0 96 Q92930,Q96A57,P35080,P62330,Q8TF01,P42858,O15020,P51153,P41440 9 +Nuclear replication fork 0.2720725333079666 0.1394173008197654 0.8891204017926413 1.0 1.0 18 P49642,Q9Y2S7,O60264,P28340,P49005,Q7L590 6 +Exocytic vesicle 0.2372131953253932 0.138983082228971 0.8894635177182908 1.0 1.0 40 Q92930,Q96A57,Q15286,P61006,O60333,Q86Y82,P20339,P51153,O43760 9 +Risc loading complex 0.6129032258064466 0.138564389581145 0.8897943847833747 1.0 1.0 2 Q9UPY3 1 +Endoplasmic reticulum protein containing complex 0.2072203402561339 0.1379974801908027 0.8902424090113741 1.0 1.0 59 Q969N2,Q96S52,P04844,Q03518,Q14165,P60468,Q9BUN8,Q9P0I2,Q9HCN8,P04439,Q8IXB1,Q04323 12 +Chromatin 0.1788846679294707 0.1352905730307166 0.8923821381848027 1.0 1.0 206 O15164,O75367,Q12824,P16403,P16402,O43633,Q9NY93,Q9GZN1,Q96L73,Q96ST3,Q96T23,Q5SSJ5,Q9H0U9,P62805,Q15022,P10412,Q9ULX6,Q9NRA0,P42771,Q9UBU8,P51608,Q92522,Q9NZM5,Q9NPF5,O95347,P07305,P17655,Q9NR30,Q13330,Q14684,Q14839,P05114,O60216,Q6UXN9,Q9HAF1,P19784,P05204,Q9NQS7,P46100,Q9Y6X9,P80723,Q9P0M6,Q02880,O60264,P17096,Q969T9,Q96QC0,Q9BUQ8,Q49A26 49 +Pore complex 0.2723259342531011 0.133664982447324 0.8936674965830183 1.0 1.0 9 P30405,P05141 2 +Nuclear speck 0.3224713155457777 0.1336111450542528 0.8937100707365881 1.0 1.0 182 Q96T37,O75438,Q86V81,Q7Z6E9,Q8N3C0,Q9Y3Y2,Q5SSJ5,Q9BY77,Q86W42,Q13247,O95391,Q15428,P08621,Q8WTT2,O94906,Q9ULX6,Q8TF01,Q12972,Q8N9N2,Q96SB8,Q9NPF4,Q9Y4C8,Q16539,Q9P2N5,Q9BZJ0,Q9GZR2,P80723,Q96DI7,Q86XP3,O95400,Q6P6C2,Q8NI27,Q9UIJ7 33 +Cell substrate junction 0.2735449897432449 0.1307182751497813 0.8959981749158201 1.0 1.0 189 O43491,Q9HCM4,Q02878,P62424,P61513,P62269,P62841,Q09666,P62701,P62280,Q13740,P61586,P39019,P41440,O15143,P62277,Q99653,O15144,P62081,P60953,Q9UBG0,Q14676,P14923,Q8N8S7,P35241,Q9UHB6,P17655,P63173,P61160,Q9UHD1,P61247,P61353,P36578,O75122,Q02952,P62899,Q13308,P78536,P84098,P62140,P28838,P39023,P32969,P62917,Q9UGI8,P62330,P35613,P17096 48 +Sarcolemma 0.2636446329885955 0.127924016453398 0.8982091048121748 1.0 1.0 26 P41440 1 +Chromosomal region 0.2073905604031891 0.1275041811701594 0.8985413640982296 1.0 1.0 178 O75367,Q53HL2,Q86V81,Q15554,Q96ST3,Q9H0A0,P62805,Q86W42,Q8NFC6,O60934,Q96SB8,Q2NKX8,O75122,Q7Z7K6,Q9HAF1,Q9NQS7,P62140,P46100,Q8NI27,P54132,Q96BK5,Q9P0M6,Q96QC0,P50748,Q9Y6D9 25 +Nuclear inner membrane 0.2618662297881921 0.1229041765087128 0.902182978328361 1.0 1.0 20 Q5JTV8,Q99720 2 +Ciliary base 0.280931082728514 0.1225536028886274 0.902460596914568 1.0 1.0 8 A0AVF1,P61006,P31323,Q13099 4 +Vesicle tethering complex 0.2605293287757112 0.1217463961906289 0.9030998676662824 1.0 1.0 24 Q9H9E3,P60953,Q9Y2D4,Q96JB2 4 +Actin cytoskeleton 0.2566208336609296 0.1198718143061531 0.9045846923730804 1.0 1.0 146 O75340,Q9UHB6,Q9Y281,P17655,Q92614,Q9Y5S2,Q09666,O15144,P20339,P78536,Q13576,P28289,O15020,P50748,Q9BTX1,P41440,P07305,Q9Y613 18 +Intrinsic component of organelle membrane 0.2581520702995226 0.1186949042444605 0.9055170738320868 1.0 1.0 127 Q969N2,O43808,Q15286,Q00325,Q96ER9,Q8TB36,O94901,Q96S52,Q86XL3,O95140,Q8TCT8,O95563,Q8NE86,Q9BUN8,Q8TB61,Q03518,P10321,P20339,Q9P2E9,Q5HYI7,P04439,P57088,Q15125,O43819,Q6P4A7,Q86Y82,Q99595,Q9HCU5,Q9P0I2,Q8WVX9,Q9UH99 31 +Nuclear chromosome 0.2340634478100199 0.1174399878270402 0.9065113975955869 1.0 1.0 96 O15164,O75367,Q12824,Q92769,Q9H4L7,Q9GZN1,Q92878,Q96ST3,Q7L590,A6NHR9,P62805,P11388,P49642,P33992,Q9UBU8,Q6ZRS2,Q9NPF5,O95347,Q9Y2S7,Q9BYG3,Q00839,O60216,P16104,Q9NQS7,P46100,P54132,P11387,Q96BK5,Q9P0M6,O60264,P28340,P49005,Q06265,Q14683 34 +Endoplasmic reticulum golgi intermediate compartment membrane 0.2554260090199056 0.1171865044738282 0.9067122611008174 1.0 1.0 26 Q03518,P61019,Q8N511 3 +Neuron to neuron synapse 0.1991810315917949 0.1158085819844614 0.9078042488438084 1.0 1.0 65 Q02878,P61006,P62269,P40123,P50914,P39019,P35222,Q15382,P05388,P30050,P62277,Q99996,P62851,Q96QK1,Q14168,P63173,P61160,Q96HC4,P18124,Q9BY67,Q00535,Q99720,P62917,P47756,P57105,P62263,P25685 27 +Cell cell junction 0.2384345085514392 0.1144608700415375 0.9088724636690846 1.0 1.0 111 Q9HCM4,Q9Y2S7,Q9HD47,Q9Y5S2,P31749,Q9Y624,P16989,P60953,O15020,P51153,P41440,Q9Y613 12 +Postsynapse 0.2090457486213685 0.1143185609561943 0.9089852694393372 1.0 1.0 130 Q02878,P61006,P62269,P40123,P50914,P61586,P46939,O15020,Q15382,O75787,P20338,P62277,Q99996,P51608,P60953,Q96CX2,P42858,P63173,P35080,Q13492,Q01970,P31749,P20339,Q9BY67,Q99720,P62917,Q86Y82 27 +Site of dna damage 0.2068535026085575 0.1130413869973452 0.9099977434026552 1.0 1.0 43 O94874,Q9BUR4,P61160,P09874,P59998,Q13185,Q9H4L7,Q9NW82,O15144,O60934,Q96SB8,Q9UMS4,P16104,Q68E01,A6NHR9 15 +Ribonucleoprotein granule 0.2050443294287064 0.1121770184491613 0.9106830507628234 1.0 1.0 122 Q9NYY8,Q7L8L6,O75175,Q02878,Q9Y5A9,Q969Z0,Q9Y3Y2,P60953,Q01085,P62312,Q9NUL7,P31483 12 +Cell cortex 0.2166441145732768 0.1096130990078173 0.9127162217546272 1.0 1.0 105 P17655,P53365,P62330,Q9UHY1,O75122,O15020,P41440 7 +Signal peptidase complex 0.5860717515827529 0.1061898029964126 0.9154317612320056 1.0 1.0 2 Q15005 1 +Trans golgi network transport vesicle membrane 0.3381598793363523 0.1052620115672073 0.91616790584367 1.0 1.0 4 O43747,O95782,Q00610 3 +Nuclear periphery 0.1531797202364744 0.0963587682215798 0.9232356378831984 1.0 1.0 60 Q9Y281,P61962,P54132,P80723,Q9ULX6,Q99848,P52272,O60216 8 +Transport vesicle membrane 0.1970702827825804 0.0958839457001889 0.9236127453012768 1.0 1.0 40 O75340,O75396,O95486,Q15286,P10321,Q86Y82,P20339,P04439,O43760,P62820 10 +Rna polymerase complex 0.1997491900908619 0.0952351382808065 0.9241280605027948 1.0 1.0 39 P19387,P62875,Q00403,O15446,Q9GZS1,O15160,P19388,P24928,P13984,O95602,P62487,Q92541,Q9H9Y6 13 +Brush border 0.2187532848581496 0.0923096074046942 0.9264520553580584 1.0 1.0 31 Q9UHB6,P41440 2 +Wash complex 0.325823358560061 0.0884571237469433 0.9295133609954144 1.0 1.0 4 Q9Y3C0,P47756 2 +Hippocampal mossy fiber to ca3 synapse 0.3636911942098989 0.0857295664727225 0.9316813979993022 1.0 1.0 3 O60716,P47756 2 +Manchette 0.5396442568585992 0.0648319375934101 0.9483078124105556 1.0 1.0 2 Q96SI9 1 +Proteasome core complex alpha subunit complex 0.2475845410627992 0.0593727635395072 0.952655206325401 1.0 1.0 7 P25788,P25787,P25789,P28066,P25786,O14818 6 +Sperm principal piece 0.523364485981296 0.0542849668560105 0.9567081266032618 1.0 1.0 2 P08237 1 +Tubular endosome 0.2901960784313749 0.0518952424373953 0.9586121651546602 1.0 1.0 4 Q9Y5X3,Q9UNH7,Q96QK1 3 +Condensin complex 0.2303743961352628 0.0458571909431221 0.963424074935904 1.0 1.0 7 Q86XI2,Q9NTJ3,Q6IBW4,Q15021,O95347,Q9BPX3 6 +Endoplasmic reticulum tubular network membrane 0.313630880579018 0.0436797940644056 0.9651596458427664 1.0 1.0 3 Q6DD88,Q8NHH9 2 +Perinucleolar compartment 0.3097219690083405 0.0414792730209888 0.9669138163642528 1.0 1.0 3 Q92879 1 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.2515658089684319 0.039802381960069 0.968250677208344 1.0 1.0 5 P48047,P24539 2 +Centriolar subdistal appendage 0.291917973462012 0.0330908635391022 0.9736021286010405 1.0 1.0 3 Q5SW79,Q14203 2 +High density lipoprotein particle 0.4320168827253429 0.0229187224477619 0.981715105964078 1.0 1.0 2 Q9BUR5 1 +Gap junction 0.2298642533936676 0.0223055985228702 0.9822041830190192 1.0 1.0 4 Q16643,Q99797,Q07157 3 +Bloc complex 0.4229725655712944 0.0216157675718952 0.9827544557669992 1.0 1.0 2 Q86YV9 1 +Juxtaparanode region of axon 0.3991558637322842 0.0191008463169471 0.984760656290685 1.0 1.0 2 Q14168 1 +Platelet dense tubular network 0.3973470003014707 0.0189554172550141 0.9848766708891988 1.0 1.0 2 P16615 1 +Platelet dense tubular network membrane 0.3973470003014707 0.0189554172550141 0.9848766708891988 1.0 1.0 2 P16615 1 +Growth cone membrane 0.3759421163702134 0.0176121493223164 0.9859482644230906 1.0 1.0 2 Q96A65 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..df47361427822a5b5614888a125e0f79a96d1888 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body fiber", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of the cytoplasmic side of the plasma membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC9", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG3", "ATG9A", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLOC1S1", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "CAB39", "CACTIN", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC86", "CCDC88A", "CCDC94", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTA", "CLTC", "CMPK1", "CNN2", "CNN3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG4", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAHD1", "FAM114A1", "FAM118B", "FAM160A2", "FAM162A", "FAM208A", "FAM49B", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GGA1", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT2", "GPAM", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD13", "HP1BP3", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGF1R", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISY1", "ITCH", "ITGB1", "ITSN2", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC59", "LRWD1", "LSM14A", "LSM2", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METTL1", "METTL13", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGAT1", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C3A", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGGT1B", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHIP", "PI4K2A", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPN1", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC38A2", "SLC3A2", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAMM41", "TAP1", "TARDBP", "TARS2", "TBC1D10A", "TBC1D17", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIO", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXN2", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UHRF1", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZSWIM8", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAR2", "ABCC4", "ABHD11", "ABHD14B", "ABT1", "ACAD9", "ACBD3", "ACO2", "ACSF3", "ACTR2", "ACTR6", "ADAM17", "ADRM1", "AFG3L2", "AGK", "AGPS", "AHNAK", "AK3", "AKAP12", "AKAP8L", "AKAP9", "AKT1", "ALCAM", "ALDH4A1", "ALG1", "ALG5", "ALKBH5", "ALYREF", "ANAPC5", "ANKLE2", "ANXA11", "AP1B1", "AP1G1", "AP2A1", "AP2S1", "APOO", "APPL1", "AQR", "ARF6", "ARFIP2", "ARL8B", "ARMC1", "ARMC10", "ARPC1B", "ARPC2", "ARPC4", "ASCC1", "ASCC3", "ATG9A", "ATL2", "ATL3", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5C1", "ATP5F1", "ATP5J2", "ATP5O", "ATP6AP2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN2", "BASP1", "BAX", "BCAT2", "BDH2", "BLM", "BOD1L1", "BOP1", "BRIX1", "BSG", "BUD23", "BYSL", "C12orf43", "C12orf73", "C1QBP", "CADM1", "CALR", "CAP2", "CAPN2", "CAPZB", "CASP3", "CBX3", "CCDC51", "CCT2", "CCT3", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDCA8", "CDK5", "CDKAL1", "CDKN2A", "CELF1", "CENPU", "CENPV", "CEP170", "CFL2", "CHD4", "CHMP2A", "CHMP4B", "CHORDC1", "CHP1", "CHTF8", "CHTOP", "CIAPIN1", "CKMT1A*", "CLASP2", "CLPB", "CLTC", "CNOT11", "CNOT3", "COG3", "COG4", "COLGALT1", "COQ8A", "COX5A", "COX6C", "COX7A2L", "CPT2", "CRNKL1", "CSNK2A2", "CSTF2", "CTNNB1", "CTNNBL1", "CTNND1", "CYC1", "DAP3", "DARS", "DBN1", "DCAF7", "DCTN1", "DCXR", "DDOST", "DDX18", "DDX21", "DDX23", "DDX27", "DDX28", "DDX42", "DDX46", "DDX47", "DDX50", "DDX54", "DDX55", "DDX56", "DENND4C", "DERL1", "DHRS7", "DHX29", "DHX30", "DHX33", "DHX38", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJB1", "DNAJC10", "DNAJC11", "DPM1", "DPP9", "DSG2", "DSP", "DVL2", "DYNLL1", "DYNLL2", "EBNA1BP2", "EBP", "ECI1", "ECSIT", "ECT2", "EEF1E1", "EIF2A", "EIF3F", "EIF3G", "EIF3I", "EIF3M", "EIF6", "EMC3", "ENAH", "ENO1", "EPB41L2", "EPB41L5", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERCC6L", "ERLIN1", "ESF1", "ESS2", "ETFB", "EXOC4", "EXOC6B", "EXOSC2", "EXOSC6", "EXOSC8", "EXOSC9", "EXTL3", "F11R", 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0.0981765691424607 0.1871299927573601 0.0015199006411711 0.0003895091576706 +Organophosphate ester transmembrane transporter activity 4 10 2.4156667836024868 0.015706427504913 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 0.1026081339138497 0.1951188871774342 0.0018222556728696 0.000513611570332 +Nucleobase containing compound transmembrane transporter activity 4 12 2.341760657688624 0.0191930186447639 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 0.1457663642848915 0.27085351108605 0.0073966983469342 0.0041132258171264 +Ligase activity forming carbon carbon bonds 2 7 2.171904754054073 0.0298628478236033 4.62378640776699 6.856796116504855 -2.028273173745319 0.0966053788189329 1.1519157673028364 0.3502806464066411 1.451790697844621 0.2179146178607854 1.0 0.0666860823201616 0.0004739047104592 0.0035377925598295 +U3 snorna binding 3 10 2.1379976289419584 0.0325169356738754 4.939320388349515 9.725728155339803 -0.7227195889424406 0.4049137650622315 2.308428525333762 0.553030664965102 0.9129675851871468 0.2985582230399923 0.0479914252810258 0.0938999510605359 0.2199219252501269 0.0832040423996277 +U4 snrna binding 0 6 2.1157566503841 0.0343655097155313 2.9393203883495147 5.890776699029126 -0.5459881721855762 0.5213193755302243 1.485760086041362 0.3119191746204451 0.7137332010826952 0.2849826243083179 0.0290719737908623 0.0574361921538736 0.1384198135311803 0.2604905630466436 +Purine nucleotide transmembrane transporter activity 4 8 2.1098980823917315 0.0348671354757259 4.334951456310679 9.441747572815531 0.9917737457277228 0.2833655940290197 2.4104227054611673 1.6217588601139772 1.262135146193827 0.3001583617421954 0.0756950383436983 0.1459927402947744 0.0064387619157215 0.0007735171269386 +Structural constituent of ribosome 48 116 1.9921364017415748 0.0463560939144724 50.27427184466019 111.97330097087378 -1.0968665227712266 0.3627287132905895 16.025617180726236 5.646698990732621 1.8496256179403383 0.3775330956912056 0.0388797865793584 0.0038742075725268 9.62471233984117e-05 8.76034647077913e-15 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d3fe70455c3679925f1fbd13900d3a46f40bc1ac --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 1383, + "title": "Average number of proteins per term", + "value": 17.342733188720175 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..54ef0bd2a451d9b15df7d929b2494463dd8f9803 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..34eeb7ef0184135e2efd1617bee36ba4215e8974 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,342 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Rna binding 0.3211745716851873 6.069346174432567 1.284320398801087e-09 1.776213536596386e-06 1.7762151129249032e-06 996 P81605,Q96T37,Q5T653,Q92614,Q86V81,P55769,Q9UI10,P62857,Q9Y3Y2,Q86W42,Q9NYY8,O95391,Q15428,Q8TCT8,Q9Y5A9,Q8NHQ9,P46013,Q7Z478,Q9BWJ5,P07305,P42696,Q1ED39,Q13868,Q9Y4C8,Q9NWH9,Q99848,P62847,P82675,Q8N983,Q99547,P62312,P55145,O43347,Q9UGI8,Q96BK5,P47914,P34896,Q8TBF4,Q96QC0,Q9NW64,Q9BSC4,P16403,Q9BRJ7,Q9Y3U8,Q9NX58,Q9H501,P82912,P62805,P31483,P10412,Q13247,Q7L8L6,Q9Y4W2,Q9BQ75,Q8TF01,Q8TDD1,Q12972,O43709,Q9ULR0,Q9NZM5,Q9NUD5,Q9H6R0,Q8WU90,Q5T160,Q9BSH4,P61353,P16989,P62314,Q9H7B2,Q9GZR2,P84098,O75152,Q96DI7,Q96GQ7,Q9Y3A2,Q969Z0,Q8IWZ8,Q6P6C2,Q00059,P61313,P08195,O75683,Q8IY81,Q9Y237,Q9NUL7,Q02878,P62424,Q9NY93,Q8TEA1,P09012,A0AV96,Q8TCS8,Q8WTT2,Q9ULX6,O75616,Q01085,Q92522,Q9BTD8,Q9NXH9,Q9Y6V7,Q8N5L8,Q13148,O43809,O95478,P36578,P62861,P62910,P83881,P62899,Q9BZJ0,Q9UJA5,P49406,Q6DKI1,Q5RKV6,Q8NI27,Q969S3,Q9H9L3,Q9H583,Q5VTL8,P83731,P09234,P16402,P62269,P62750,P62841,Q09666,Q7Z6E9,Q96ST3,Q9BY77,Q9H0A0,Q9NVP1,Q9Y6A4,Q15056,P62277,Q13595,Q13823,P42771,Q96EY7,Q96KR1,Q99590,Q9BU76,Q9BUJ2,Q9NP81,Q8N9N2,P33240,Q5T440,O60832,O76021,P26373,P63173,Q12788,Q14151,Q14684,Q92620,Q9BY44,Q9BYG3,Q9H0S4,Q9P2E9,Q9P2N5,Q9UNQ2,Q9Y2R9,Q9BZE4,P60468,P05204,P39023,P32969,P60866,P62917,P78406,Q96RP9,Q86XP3,Q92665,Q99700,Q9H9Y2,Q9UMY1,Q13895,Q14527,Q15637,Q06265,P05141,P00505,P22087,P61513,P82914,Q2NL82,Q68CQ4,Q8N3C0,Q8NHU6,Q9BYD6,Q9Y3A5,Q15022,Q07021,O15446,P08621,O94906,P46087,P49750,P50995,P51608,P52272,P46776,P62081,Q8TDN6,Q96CX2,Q96B26,Q92879,Q9BQ39,Q9NR30,Q12905,Q9UNP9,O15213,P04439,P08579,O75127,P17480,P55084,Q99575,Q15427,Q86UE4,Q96DE0,Q9BUQ8,Q9NW13,Q9NX20,Q9NXG2,P62244,Q14137,O00541,O15226,P09874,P18077,P24928,P50914,P62701,P62280,P39019,Q8WXA9,Q8WX92,Q8IYB8,Q9Y3D9,Q9NQ55,Q9UN86,Q9Y285,Q9Y520,Q9Y6M1,Q5T8P6,P13667,P15531,P35241,P52758,P61247,Q16513,Q13206,P62318,P61604,Q8IY67,Q92541,Q9Y2L1,Q6NSI4,Q6P2Q9,Q5JTZ9,O75475,P61011,P62487,Q12906,P50454,Q9BQG0,Q8NEF9,Q8IXT5,Q7L2H7,Q9H2U1,Q9BVJ6,Q9ULW3,Q9HAU5,Q9UKA9,Q15233,Q86U42,Q15046,O00567,O60306,P08708,P11388,P30050,Q13601,Q13347,P82979,P62854,P62753,P62266,Q96AG4,Q15424,Q8NE71,Q8IX01,Q7L014,Q9BUR4,Q9Y3I0,Q9BV44,Q9BXY0,Q9P2K5,Q14697,O95793,Q14690,P15924,Q13435,O15347,O75390,O00148,P11387,P62304,Q00688,P84090,P78346,P49411,Q8NI36,Q8NC51,Q8IX18,Q8IYB3,Q9H000,Q92769,Q96I25,Q9NR50,Q6P1L8,P20042,O75643,O75821,O76003,P06748,P09001,Q13242,Q12849,Q05519,P34897,P51398,P46777,P40429,Q8IWZ3,Q7L2E3,Q02543,Q15061,Q13523,Q13428,Q04837,Q9Y5B9,Q9H6S0,Q9UKM9,Q9UPN3,Q9Y224,Q9Y2R5,Q9Y3B7,Q02978,O60869,Q00839,P18124,P15880,P09132 354 +Rrna binding 0.6024111548878566 3.518588703249665 0.0004338487506094 0.4512668477737794 0.3000064110464546 47 P62269,P62750,Q9NY93,P62701,P62280,Q68CQ4,P82912,Q9Y3A5,Q9NYY8,Q7L8L6,P62277,Q8TCT8,Q96EY7,O75616,Q8TDN6,Q9NZM5,Q9NR30,Q9BSH4,Q9Y2R9,Q9H7B2,P39023,P32969,P62917,Q9H9Y2,Q9NX20,Q9NUL7 26 +Atp dependent activity acting on rna 0.457912051508369 2.4313670178079123 0.0150419689375354 0.9999999992116582 0.6092928240303049 50 Q9H2U1,Q9NY93,Q9NVP1,O75643,O60306,Q8IYB8,Q8NHQ9,Q8TDD1,Q7L2E3,Q7Z478,Q9H6R0,Q9BQ39,Q7L014,Q9Y6V7,Q9NR30,Q92620,Q13206,Q9H0S4,O00148,Q96GQ7,Q86XP3,Q9BUQ8,Q8IX18,Q9NUL7 24 +Nucleotide transmembrane transporter activity 0.7573980911298014 2.4156667836024868 0.015706427504913 0.99999999968998 0.6092928240303049 10 O15439,Q9BSK2,P41440,Q8TB61 4 +Organophosphate ester transmembrane transporter activity 0.7573980911298014 2.4156667836024868 0.015706427504913 0.99999999968998 0.6092928240303049 10 O15439,Q9BSK2,P41440,Q8TB61 4 +Nucleobase containing compound transmembrane transporter activity 0.7411667937261135 2.341760657688624 0.0191930186447639 0.9999999999977088 0.6092928240303049 12 O15439,Q9BSK2,P41440,Q8TB61 4 +Ligase activity forming carbon carbon bonds 0.7982316977624531 2.171904754054073 0.0298628478236033 1.0 0.6092928240303049 7 Q96RQ3,P05165 2 +Amide transmembrane transporter activity 0.9058987827947524 2.140030052129025 0.0323523381563783 1.0 0.6092928240303049 4 O15439,P41440 2 +U3 snorna binding 0.7013887571862278 2.1379976289419584 0.0325169356738754 1.0 0.6092928240303049 10 Q2NL82,P55769,Q12788 3 +Purine nucleotide transmembrane transporter activity 0.7560443634633127 2.1098980823917315 0.0348671354757259 1.0 0.6170923032647676 8 O15439,P41440,O43808,Q8TB61 4 +Biotin binding 0.878917341059428 2.0345656051731753 0.0418946011280472 1.0 0.6431197708339003 4 Q96RQ3,P05165 2 +Structural constituent of ribosome 0.5425865911073743 1.9921364017415748 0.0463560939144724 1.0 0.6538465914027535 116 Q7Z7F7,P83731,Q5T653,Q02878,P62424,P61513,P18077,P82914,Q9Y3U8,P50914,P62269,P62701,P62280,P62750,P62841,P62857,Q9Y3D3,Q9UHA3,P39019,Q9BYD6,P82912,P62277,P46776,P62081,P26373,P63173,P61353,P36578,P62910,P62847,P82675,Q8N983,Q9H2W6,P83881,P62899,Q9Y2R9,P84098,P39023,P32969,P60866,P62917,P49406,Q6DKI1,P47914,Q92665,P61313,Q9NX20,P62244 48 +Carbohydrate derivative transmembrane transporter activity 0.7233000724842324 1.9589891671044155 0.0501140554509702 1.0 0.6538465914027535 8 P41440,O43808,Q8TB61 3 +Thioesterase binding 0.921262235276556 1.908651226039272 0.0563070989837868 1.0 0.6956111234469591 3 P62330 1 +Modified amino acid transmembrane transporter activity 0.914921152888482 1.8846757063905453 0.0594736341937314 1.0 0.7034546870069056 3 P41440 1 +Adp binding 0.6294827281296149 1.8149174000623811 0.0695366041285496 1.0 0.7034546870069056 19 Q8NI60,Q92614 2 +Profilin binding 0.8208232070450332 1.80391087910983 0.0712452792240365 1.0 0.7034546870069056 4 P42858 1 +Electron transfer activity 0.4062985551614102 1.7986559825744093 0.0720731158515781 1.0 0.7034546870069056 54 P23368,O14548,P20674,P19404,O95139,O75438,O43676,O95168,P38117,O75380,Q9P0J0,P28331,P08574,P03915,P30038,Q16795,Q9UDW1 17 +Nucleosome binding 0.5614041911017466 1.7788752350813293 0.0752602190704179 1.0 0.7034546870069056 32 P10412,O75367,Q12824,P16403,P16402,Q9GZN1,P05114,Q5SSJ5,Q92522,Q49A26,P07305 11 +Mannosyltransferase activity 0.8120663650075419 1.7687495977042345 0.076935671329668 1.0 0.7034546870069056 4 O60762,O75340,Q6ZXV5 3 +U1 snrna binding 0.6980850728434852 1.7265605590225934 0.0842466144479752 1.0 0.7034546870069056 7 P08579,P08621,P09012,P09234 4 +Catalytic activity acting on a rrna 0.6466130904198824 1.7196415086720718 0.0854976260633355 1.0 0.7034546870069056 9 Q9UNQ2,O43709,P22087,Q8IY81 4 +Transferase activity transferring nitrogenous groups 0.6710385999062175 1.7138958885755873 0.0865478482895376 1.0 0.7040922010848858 8 P00505,O15382,P04406,Q8TD30,Q06210 5 +Mrna 3 utr au rich region binding 0.6173459323797709 1.7025635209964731 0.0886497816460798 1.0 0.7124986275973645 12 O43809,Q96B26,Q01085,Q12906,Q06265,P31483 6 +Minor groove of adenine thymine rich dna binding 0.7924779386520738 1.6897602483213026 0.0910738316911894 1.0 0.7156001781212804 4 P07305 1 +General transcription initiation factor activity 0.7912465188358233 1.6847798337238231 0.0920310570798221 1.0 0.7156001781212804 4 Q00403,P13984 2 +Oxidoreductase activity acting on a heme group of donors 0.6882169007679397 1.6817400583927369 0.0926192566042727 1.0 0.7156001781212804 7 O14548 1 +Primary active transmembrane transporter activity 0.3896663534296468 1.6650604981252166 0.0959006866065019 1.0 0.7247576479606133 52 O14548,P20674,P21283,P19404,O75438,O43676,O15439,Q03518,O95139,O95168,O75380,Q9P0J0,P28331,P08574,Q9Y5K8,P03915,Q9UDW1 17 +Nucleosomal dna binding 0.5951273956556298 1.649491711955298 0.0990469397464761 1.0 0.7399540809155996 21 P10412,O75367,Q12824,P16403,P16402,P05114,Q92522,P07305 8 +Oxidoreduction driven active transmembrane transporter activity 0.5253853298468164 1.5766862390676768 0.1148677382783178 1.0 0.7863038764346892 33 O14548,P20674,P19404,O95139,O75438,O43676,O95168,O75380,Q9P0J0,P28331,P08574,P03915,Q9UDW1 13 +Oligosaccharyl transferase activity 0.7103225425670132 1.5713945861846446 0.1160910227269522 1.0 0.7863038764346892 5 Q9Y673,P04844 2 +Map kinase kinase activity 0.6778204346578182 1.536564381759033 0.1244000204711004 1.0 0.7863038764346892 6 P46734 1 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.5842002699228599 1.5295387118706711 0.1261309498373768 1.0 0.7863038764346892 11 Q13576 1 +Protein binding involved in heterotypic cell cell adhesion 0.7429864253393671 1.4884177059621344 0.1366407700064535 1.0 0.8121767581265689 4 Q08722,P14923,Q14126 3 +Solute anion antiporter activity 0.6853754669134765 1.4635580331911238 0.1433147462512967 1.0 0.8282959482198978 5 P41440 1 +Rna polymerase ii general transcription initiation factor activity 0.7969788014058992 1.4317264303746189 0.1522221292318266 1.0 0.8411242595483565 3 P13984 1 +Chromatin dna binding 0.4748968327751989 1.4183709916611609 0.1560824801455327 1.0 0.8411242595483565 37 P10412,O75367,Q12824,P16403,P16402,Q9P0M6,Q969T9,P05114,Q92522,P05204,P07305 11 +Nucleotide phosphatase activity acting on free nucleotides 0.7932150340728297 1.4171171350879976 0.1564486835533483 1.0 0.8411242595483565 3 Q9BRJ7 1 +Active transmembrane transporter activity 0.4008560073364292 1.4120455627623674 0.1579365458904309 1.0 0.8411242595483565 70 P05141,O75438,O43676,O15439,Q00325,P41440,Q9UDW1,P19404,Q8NE86,P28331,O14548,P20674,Q03518,O75380,P03915,O95139,P08195,O95168,Q9Y5K8,Q9P0J0 20 +Dna clamp loader activity 0.6056987317363917 1.401821532008474 0.160968546944952 1.0 0.8464619788017818 8 P0CG13,P41440 2 +Vitamin binding 0.3697217649776261 1.396829625924838 0.1624648110753175 1.0 0.8510940671104702 48 P05165,Q96RQ3,Q8TD30,P34896,O60568,P41440 6 +G protein activity 0.5566696229686954 1.3774410579727998 0.1683759262417112 1.0 0.8548939827266631 15 Q9NVJ2,Q15286,P51148,P20339,P60953,P62820 6 +O methyltransferase activity 0.591362108766927 1.3328702001919766 0.1825744033633554 1.0 0.886099333411029 8 Q86VU5,Q8IY81,O60725 3 +Dna dna annealing activity 0.6312920847090878 1.330148035491248 0.1834695014525902 1.0 0.886099333411029 6 P54132 1 +Nadplus kinase activity 0.7705066344994002 1.328903623850893 0.1838797681173678 1.0 0.886099333411029 3 Q4G0N4,Q9NRA0 2 +Pyruvate dehydrogenase activity 0.7040723981900463 1.328893128595725 0.1838832311561571 1.0 0.886099333411029 4 P09622,P08559,P10515 3 +Cyclosporin a binding 0.5430937739619776 1.3116763552591586 0.1896293579588108 1.0 0.9074650590208838 11 Q9Y3C6,Q96BP3,Q9UNP9,P30405,P45877 5 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.762789471333521 1.298915156794518 0.1939730475123555 1.0 0.9154181338393984 3 P42574 1 +Phosphatidylinositol 3 phosphate binding 0.583128270671869 1.2932499261972688 0.1959246331283166 1.0 0.9154181338393984 8 Q9UMY4 1 +Rdna binding 0.6922307890413393 1.2802606361889617 0.2004534867903582 1.0 0.9191981987794006 4 O75367,Q9H6R0 2 +5s rrna binding 0.6132430855651595 1.2497641456358055 0.2113857172023099 1.0 0.9191981987794006 6 Q9NZM5,Q9H7B2 2 +Telomerase activity 0.7493968636912061 1.2468887889590057 0.2124382780350804 1.0 0.9191981987794006 3 O60832,Q15554 2 +Rna directed dna polymerase activity 0.7493968636912061 1.2468887889590057 0.2124382780350804 1.0 0.9191981987794006 3 O60832,Q15554 2 +Thiamine pyrophosphate binding 0.6835595776772256 1.244650080356682 0.2132604030602447 1.0 0.9191981987794006 4 Q02218,A1L0T0,Q9UJ83 3 +Organic anion transmembrane transporter activity 0.5104194955883449 1.2390625668291149 0.2153223283838758 1.0 0.9191981987794006 26 O43808,O15439,P08195,P41440,Q8TB61 5 +Adp transmembrane transporter activity 0.6803755962602377 1.2315772290724585 0.218107051340811 1.0 0.9191981987794006 4 O43808 1 +Cargo adaptor activity 0.5479255478425475 1.2258068211016573 0.2202713797111306 1.0 0.9191981987794006 9 Q5SW96,O95782,P53680 3 +Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication 0.7427623642943368 1.2211330123304427 0.222035662230313 1.0 0.9191981987794006 3 P14923,Q14126 2 +Protein kinase a regulatory subunit binding 0.5674640905849938 1.2179016821544555 0.2232613369094522 1.0 0.9191981987794006 8 Q9ULX6,Q9H3P7,Q99996 3 +Dna topoisomerase activity 0.7385404101326891 1.2047520137975858 0.2282990497930035 1.0 0.9286399584227172 3 Q02880,P11388 2 +Trna specific ribonuclease activity 0.6729616203165321 1.2011478875079176 0.2296938399489443 1.0 0.9315735502914664 4 Q99575,P78346 2 +Snrnp binding 0.6014662347357252 1.197308370516401 0.231186383042105 1.0 0.932833965265884 6 P62314,P09012 2 +Pre mrna binding 0.5141076993984258 1.1672332790947015 0.2431161748731798 1.0 0.9475233512794844 20 Q9NW64,Q13247,P09234,Q13148,O95391,Q15637 6 +Phosphatase inhibitor activity 0.5743675233599406 1.1578108082321643 0.2469412516915412 1.0 0.9475233512794844 7 Q96QC0,Q12972 2 +Snrna binding 0.4893359334198137 1.1555082063662383 0.2478823740135798 1.0 0.9475233512794844 28 Q9NW64,P09234,Q9NR30,P08621,P55769,Q9NY93,P62318,P08579,P09012 9 +Ribonuclease p activity 0.7234620024125509 1.1463284128630618 0.2516592908293185 1.0 0.948350951544816 3 Q99575,P78346 2 +7s rna binding 0.5704996607004853 1.1399719985280024 0.2542979671612935 1.0 0.9556904581088828 7 P09132,P61011,Q13868 3 +Organic acid binding 0.4611196704389876 1.1285281164996053 0.2590969494913708 1.0 0.963255594480016 33 P05165,Q96RQ3,P34896,O60568,P41440 5 +Acyl coa binding 0.5071492468955475 1.1156116285830529 0.264588412339672 1.0 0.9650175616449538 12 P22307,O75521,Q9H3P7,Q9H845,P40939,Q02252,Q92947,O00154 8 +Fatty acid derivative binding 0.5071492468955475 1.1156116285830529 0.264588412339672 1.0 0.9650175616449538 12 P22307,O75521,Q9H3P7,Q9H845,P40939,Q02252,Q92947,O00154 8 +Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor 0.6045271925882503 1.112209995590796 0.2660478711993632 1.0 0.9650175616449538 5 Q15738,Q8NBQ5 2 +Transferase activity transferring sulphur containing groups 0.5246867611589816 1.1094828904668714 0.2672219213782218 1.0 0.9650175616449538 9 P55809,Q5VV42 2 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.6505720710585715 1.1094261944809027 0.2672463673969756 1.0 0.9650175616449538 4 P04844 1 +Heparin binding 0.5043980526559467 1.1072166930163745 0.2682002519684596 1.0 0.9659399699801554 11 P10586 1 +Large ribosomal subunit rrna binding 0.6472146043863196 1.0957051926554322 0.2732078095489967 1.0 0.9688517635221484 4 Q9Y3B7,P30050 2 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.7097047092283733 1.0931751245409134 0.2743169166685753 1.0 0.9688517635221484 3 P08559 1 +Rna polymerase i transcription regulatory region sequence specific dna binding 0.6464555052790361 1.0926045174415095 0.2745674784318916 1.0 0.9688517635221484 4 P17480,Q12824,P51532 3 +Bh3 domain binding 0.709437144762019 1.0921431606166028 0.2747701810793266 1.0 0.9688517635221484 3 Q07820 1 +Bh domain binding 0.709437144762019 1.0921431606166028 0.2747701810793266 1.0 0.9688517635221484 3 Q07820 1 +Histone methyltransferase activity h3 k4 specific 0.5996109896598536 1.0909074133102872 0.2753136247752743 1.0 0.9688517635221484 5 Q6UXN9,Q15291 2 +Atp transmembrane transporter activity 0.5973638117735968 1.081178543561896 0.2796177004608089 1.0 0.9704835057697996 5 Q6NUK1,P05141,O43808 3 +Aspartic type peptidase activity 0.5965794485092526 1.0777840914239505 0.2811301206530554 1.0 0.9704835057697996 5 Q8TCT8 1 +Rna polymerase activity 0.4937078925671637 1.044414064529668 0.296293859275474 1.0 0.9798533388702334 19 P19387,Q13503,P62875,O15446,Q9GZS1,O15160,P19388,P24928,O95602,P62487,Q9H9Y6 11 +Ribosomal small subunit binding 0.4889033390694629 1.026141112073607 0.3048250740413434 1.0 0.991936652703948 11 O75616,Q15056,Q7Z478 3 +Intramolecular transferase activity phosphotransferases 0.6255601783897946 1.0075290157346974 0.3136806213203882 1.0 0.9978050343373394 4 O95394 1 +Gdp binding 0.4609668167210001 1.0017948930467917 0.3164426642633815 1.0 0.9978050343373394 29 Q9NVJ2,Q92930,Q9NP72,P51148,Q15286,P62330,P20339,P61019,Q15382 9 +Ubiquitin protein transferase inhibitor activity 0.5213105775144664 0.9972503988570356 0.3186429831948394 1.0 0.998065936616821 8 P62841,P60866,P62081,P46777 4 +Mitochondrial ribosome binding 0.6219230920612382 0.992785746219212 0.3208143776590093 1.0 0.998065936616821 4 Q9BSH4 1 +Oxidoreductase activity acting on diphenols and related substances as donors 0.6209788683385196 0.9889619671691032 0.3226817501356316 1.0 0.9982922283134076 4 Q9UDW1,P08574 2 +Ubiquinol cytochrome c reductase activity 0.6209788683385196 0.9889619671691032 0.3226817501356316 1.0 0.9982922283134076 4 Q9UDW1,P08574 2 +Active ion transmembrane transporter activity 0.4103018579935681 0.9841811120870516 0.3250264709486081 1.0 0.9982922283134076 38 O14548,P20674,P05141,P21283,O15439,Q00325,Q9Y5K8,P08195,P41440,Q9UDW1 10 +Peptide transmembrane transporter activity 0.9409104612601734 0.9784644765786388 0.3278446524467722 1.0 0.9986985778279428 2 O15439 1 +Signal recognition particle binding 0.5727107657846522 0.9749112535690307 0.3296042834184067 1.0 0.9996830593614262 5 P08240,Q9BUN8 2 +Carboxylic acid binding 0.4207626509813904 0.9681183238456872 0.3329852795235568 1.0 1.0 36 P05165,Q96RQ3,P34896,O60568,P41440 5 +Gtp dependent protein binding 0.4734468669279135 0.954642415673689 0.339758559644292 1.0 1.0 10 P60953,P53365 2 +Phosphatidylinositol phosphate binding 0.3613815021404183 0.9530224640433218 0.3405786889730433 1.0 1.0 44 Q9UMY4,Q13576,P35080,P53365 4 +Mhc class i protein binding 0.511938877741287 0.9529563007052532 0.3406122122747312 1.0 1.0 8 Q03518 1 +Proteasome activating activity 0.5456944171309464 0.9503088627979692 0.3419553368596073 1.0 1.0 6 P62191,P35998,P17980 3 +Dna translocase activity 0.9318661441061196 0.9485028487601708 0.3428735232423032 1.0 1.0 2 Q2NKX8 1 +Mrna 5 utr binding 0.4721631735638927 0.9474170968658088 0.3434262825196121 1.0 1.0 22 P62277,Q9H2U1,P34897,P61247,P46777,P34896,P62081,Q9Y6M1,P82912,O76021 10 +Laminin binding 0.6674220052602765 0.9313475899396352 0.3516737920960722 1.0 1.0 3 O94813 1 +Protein self association 0.4723371887051825 0.9275787032708578 0.3536261490575481 1.0 1.0 13 O14641 1 +Potassium channel regulator activity 0.4848271235520492 0.9125942759482985 0.3614559659233314 1.0 1.0 9 Q99653,P31749,Q99996 3 +Peptide antigen binding 0.5551590780993817 0.8999763850370889 0.368132818013682 1.0 1.0 5 Q03518,P10321 2 +14 3 3 protein binding 0.553551370538085 0.8931516438161123 0.371775969771988 1.0 1.0 5 P31749 1 +Nadh dehydrogenase activity 0.457782003112346 0.8885733400991903 0.3742324242454733 1.0 1.0 24 O95139,O75438,O43676,O95168,O75380,P28331,P03915,Q9P0J0 8 +Xenobiotic transmembrane transporter activity 0.6557164850538192 0.8871453860969475 0.3750006314052863 1.0 1.0 3 P41440 1 +S acyltransferase activity 0.5949725516075546 0.8843690857270895 0.3764970054480274 1.0 1.0 4 P10515 1 +Atp dependent activity acting on dna 0.3246847454318259 0.8729914870637288 0.3826677178150257 1.0 1.0 58 P11388,Q8IYB8,P46100,P28370,Q92614,P54132,Q9H2U1,Q02880,P0CG13,Q14839,Q2NKX8,P13984,O60264,Q8N3C0,Q9UNY4,Q14527,P41440,P35251 18 +Antiporter activity 0.4734140985396003 0.8572640889950445 0.3912989502340571 1.0 1.0 9 P08195,O95202,P05141,P41440 4 +G quadruplex dna binding 0.5435722140186562 0.8509625668198212 0.3947901471409658 1.0 1.0 5 Q92878,P54132,Q9H2U1 3 +Alpha catenin binding 0.5838175392136895 0.8400302177634621 0.40089144401 1.0 1.0 4 P35222,P14923 2 +Sulfur compound transmembrane transporter activity 0.5368454996273324 0.8227083691748536 0.4106738548832598 1.0 1.0 5 O15439 1 +Translation initiation factor binding 0.4537938372191702 0.8219836346822793 0.4110862110826541 1.0 1.0 17 Q9UI10 1 +Retinoid x receptor binding 0.8893578534820605 0.8101536077738466 0.4178518970425036 1.0 1.0 2 Q96L73 1 +Protein phosphatase 1 binding 0.5317525697226027 0.8014265302114297 0.4228847613786699 1.0 1.0 5 Q96QC0,P62136 2 +Protein phosphatase regulator activity 0.4435922652557949 0.7884516013368215 0.4304325977862375 1.0 1.0 22 Q86XL3,Q96QC0,Q12972,Q5H9R7,Q15435 5 +Secondary active transmembrane transporter activity 0.446333463184945 0.7840363063459787 0.4330188070714089 1.0 1.0 18 P08195,Q8NE86,P41440 3 +Structural molecule activity conferring elasticity 0.8806150135664679 0.7823022164835047 0.4340369845605085 1.0 1.0 2 P11047 1 +Glycosyltransferase activity 0.3073983556366126 0.7799216051016322 0.4354370206080544 1.0 1.0 48 O60762,Q8NBJ5,O43909,O75340,P04844,Q6ZXV5,P46977,Q9Y673,Q04446,Q9BT22,O60568,Q9H488,Q9H974,Q7Z4H8 14 +Pre mrna intronic binding 0.526150714764055 0.7781368519907899 0.4364883394522794 1.0 1.0 5 P22626,Q6P2Q9,Q13148 3 +Monocarboxylic acid transmembrane transporter activity 0.5248347557415793 0.772684827145857 0.4397089283789144 1.0 1.0 5 O15439 1 +Protein serine threonine kinase inhibitor activity 0.4387942857990288 0.7709712462659801 0.44072397505888 1.0 1.0 11 P42574,O75367,P42771 3 +Copper chaperone activity 0.6236734851154717 0.7681037169553728 0.4424255688421907 1.0 1.0 3 O43819 1 +Metallochaperone activity 0.6236734851154717 0.7681037169553728 0.4424255688421907 1.0 1.0 3 O43819 1 +Enoyl coa hydratase activity 0.5029643094593383 0.7655461643505665 0.443946387951996 1.0 1.0 6 P42126,P40939,P55084 3 +Dolichyl phosphate mannose protein mannosyltransferase activity 0.8748869460355722 0.7641849522848613 0.4447570325739827 1.0 1.0 2 Q6ZXV5 1 +Core promoter sequence specific dna binding 0.4388740742439664 0.7635123880831047 0.4451578771728699 1.0 1.0 12 O75367,Q12824,Q00403 3 +Tap binding 0.5616132867780206 0.753011310121174 0.4514431175876416 1.0 1.0 4 Q03518,P10321 2 +Glucosyltransferase activity 0.4317701497633916 0.7457757659825879 0.4558028815553094 1.0 1.0 10 O60568 1 +7sk snrna binding 0.5182774655626974 0.7456327400971053 0.4558892996308621 1.0 1.0 5 Q9NY93 1 +Death domain binding 0.559228019742718 0.7437774390386952 0.4570111312533873 1.0 1.0 4 Q07820 1 +Poly pyrimidine tract binding 0.4360263852742344 0.7314095539294393 0.4645290313818029 1.0 1.0 16 O43347 1 +C3hc4 type ring finger domain binding 0.6118409194728436 0.7250478146962737 0.4684226974635885 1.0 1.0 3 P31689 1 +Very long chain fatty acid coa ligase activity 0.6118122155586561 0.7249440600214188 0.4684863493084776 1.0 1.0 3 Q4G176 1 +Single stranded dna endodeoxyribonuclease activity 0.6109770808202692 0.7219268699352922 0.4703394401938137 1.0 1.0 3 Q92878,P18887 2 +Transketolase or transaldolase activity 0.61067551266586 0.7208380897254357 0.4710091373186058 1.0 1.0 3 A1L0T0,P29401 2 +Adenylate cyclase binding 0.5481510451129905 0.7012298512641234 0.4831595833617415 1.0 1.0 4 Q02952 1 +Sulfur compound binding 0.3214702275501749 0.6875704372733953 0.491723330080853 1.0 1.0 45 P05165,Q96RQ3,P47914,Q9H3P7,P10586 5 +Protein carboxyl o methyltransferase activity 0.5409629187085894 0.6739373186131061 0.5003511650319412 1.0 1.0 4 O60725 1 +Rna polymerase ii core promoter sequence specific dna binding 0.4991885173078432 0.6681038045128964 0.5040673334831591 1.0 1.0 5 O75367 1 +Organic acid transmembrane transporter activity 0.4187606880730796 0.651493065197772 0.5147282522279752 1.0 1.0 21 O15439,P08195,P41440 3 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.4079458579156613 0.64977438307141 0.5158379683608008 1.0 1.0 27 O95139,O75438,O43676,O95168,O75380,P28331,P03915,Q9P0J0 8 +Neutral amino acid transmembrane transporter activity 0.4943342218091534 0.6487164177203146 0.516521690556069 1.0 1.0 5 P08195 1 +Protein membrane adaptor activity 0.4108393038532897 0.645830451605406 0.5183891645553611 1.0 1.0 10 O75340,P49790,Q9UH99,O94901 4 +Double stranded methylated dna binding 0.8314742236961048 0.6307662579027585 0.5281933688113463 1.0 1.0 2 O75367 1 +Myosin v binding 0.4892539091852751 0.628585380021128 0.5296205341595701 1.0 1.0 5 P20340,P61006,P61026 3 +Phosphatase regulator activity 0.4021053962241834 0.5953397241487809 0.551616407641538 1.0 1.0 25 Q86XL3,Q96QC0,Q12972,Q5H9R7,Q15435 5 +Sulfurtransferase activity 0.5741925806211556 0.5923661026793628 0.553605460007784 1.0 1.0 3 P25325 1 +Atp dependent dna dna annealing activity 0.5187108443649135 0.5912819773754898 0.5543315032226461 1.0 1.0 4 P46100 1 +Fructose binding 0.5733997824168268 0.5896546685270901 0.5554221924252842 1.0 1.0 3 P17858 1 +Protein deacetylase activity 0.5170483364430114 0.585230087852602 0.5583930164105013 1.0 1.0 4 Q92769 1 +Snorna binding 0.3903699484297956 0.5847808917438404 0.5586950543057649 1.0 1.0 29 Q12788,Q9NR30,Q9BRJ7,Q8TCT8,P55769,Q9NY93,Q2NL82,Q68CQ4,Q13895,Q9H583,O60832 11 +Misfolded protein binding 0.4040561787865029 0.584148802296411 0.5591202034234677 1.0 1.0 14 Q9BUN8,Q9HCN8,P17066 3 +Peroxiredoxin activity 0.4589071830200711 0.583863091563106 0.5593124265950606 1.0 1.0 6 Q13162 1 +Dioxygenase activity 0.4003743158863202 0.5705949114940962 0.5682742686179847 1.0 1.0 23 O00625,O60568 2 +Lamin binding 0.4105944748861095 0.5682328591979261 0.5698768621301056 1.0 1.0 9 Q5JTV8,Q9ULX6,Q9UH99,O94901 4 +Dna binding bending 0.4736618216062585 0.5679154508379225 0.570092379965393 1.0 1.0 5 P11388,Q00059 2 +Phosphatidylinositol binding 0.3051109582903379 0.5465339294711198 0.5846989714314441 1.0 1.0 68 P35080,P53365,Q9UMY4,Q9UJY5,Q13576 5 +Mhc protein binding 0.4048688837286366 0.5437253382857283 0.5866304933627342 1.0 1.0 9 Q03518 1 +Complement binding 0.5597104945717637 0.5434605272621618 0.5868127614226186 1.0 1.0 3 Q07021,P27797 2 +Opsonin binding 0.5597104945717637 0.5434605272621618 0.5868127614226186 1.0 1.0 3 Q07021,P27797 2 +Estrogen receptor binding 0.3904726990240957 0.528707438341488 0.5970084163869624 1.0 1.0 13 Q8TDD1,Q969T9 2 +G protein coupled receptor activity 0.7943925233644733 0.523472098577817 0.6006457625647361 1.0 1.0 2 Q99720 1 +Rna polymerase ii c terminal domain binding 0.4601763252949709 0.5169676864805517 0.6051787161116557 1.0 1.0 5 Q00839,O95104,Q92541 3 +Retinoic acid receptor binding 0.4275322506783244 0.5138655113224668 0.6073460217332336 1.0 1.0 7 Q96L73 1 +Cation cation antiporter activity 0.789870364787449 0.5108886507352528 0.6094290286637443 1.0 1.0 2 P08195 1 +Calcium cation antiporter activity 0.789870364787449 0.5108886507352528 0.6094290286637443 1.0 1.0 2 P08195 1 +Antigen binding 0.4353537467942531 0.4924710887630135 0.62238635527356 1.0 1.0 6 Q03518,P10321 2 +Telomerase rna binding 0.3782990823671417 0.4831666091377289 0.6289774420518737 1.0 1.0 12 Q9BUR4,Q9H2U1,Q96BK5,P62318,Q00839,O60832 6 +Annealing activity 0.3762924669927139 0.4827319841047522 0.6292860501854547 1.0 1.0 11 P46100,P54132 2 +2 iron 2 sulfur cluster binding 0.3739604242031129 0.4820286525613452 0.6297855921654851 1.0 1.0 10 P19404,P22830,P47985,P28331,Q6FI81 5 +Galactosyltransferase activity 0.4502160415400955 0.4803672360784865 0.6309662873088906 1.0 1.0 5 O60568 1 +Protein kinase a binding 0.3833642520636382 0.4793528953955188 0.6316875979412795 1.0 1.0 18 Q96M27,Q9ULX6,Q9H3P7,Q99996,Q02952 5 +Hsp70 protein binding 0.3819924353899349 0.4775266542847865 0.6329871453382867 1.0 1.0 16 O60884,P31689,P37198,Q07812,P25685,Q8IXB1 6 +Molecular function activator activity 0.3794643601621392 0.4752735115727378 0.6345920365395223 1.0 1.0 14 O60884,P31689,P31749,P54709,Q5JTV8 5 +Carbohydrate kinase activity 0.4026228887434854 0.4721882160019958 0.6367924501244568 1.0 1.0 8 P51570,P52789,Q9Y223,P17858 4 +Hexosyltransferase activity 0.3375267646082502 0.4654167103081633 0.6416330698303063 1.0 1.0 37 O60762,Q8NBJ5,O43909,O75340,P04844,Q6ZXV5,Q9Y673,Q04446,O60568,Q9H488,P46977,Q7Z4H8 12 +Dna secondary structure binding 0.3735754323878348 0.4634241323958289 0.6430603841601665 1.0 1.0 12 P07305,P54132 2 +Lipid kinase activity 0.7702743442870075 0.4577728647630531 0.6471156327503429 1.0 1.0 2 Q9NRA0 1 +Low density lipoprotein particle receptor binding 0.3827914911743917 0.4531811436469337 0.6504183093319384 1.0 1.0 9 Q5SW96,P31689,Q13492 3 +Nuclear receptor coactivator activity 0.3754055907079582 0.4495378182847805 0.6530437331619514 1.0 1.0 22 O60244 1 +Carboxy lyase activity 0.3632082254821265 0.4214558590162116 0.6734222372524055 1.0 1.0 12 P23368,P38435,Q6P587,P30046 4 +Protein transmembrane transporter activity 0.3589891359987803 0.421312732926662 0.6735267336158328 1.0 1.0 10 Q9NS69,Q07820 2 +Carbohydrate binding 0.2633077291497493 0.42067207604923 0.6739945544323662 1.0 1.0 48 Q16706,Q14165,Q96C23,P35613,O60568,Q9UBG0 6 +Cis trans isomerase activity 0.3626131840990364 0.4154561208755271 0.6778080305776475 1.0 1.0 26 P26885,Q96BP3,P30405,Q9Y237,Q9H2H8,P45877 6 +Gtpase activity 0.3310112474287673 0.4119369879347184 0.680385609189547 1.0 1.0 96 Q15286,P61006,Q96P47,Q969Y2,Q15382,P20338,O95140,Q9NP72,Q13823,P60953,P51153,P51148,P20339,Q9BZE4,Q9BZG1,Q92930,Q9NVJ2,Q96RP9,P62330,P61019,P62820 21 +Palmitoyltransferase activity 0.4259330002571413 0.3953536311984122 0.6925819243963716 1.0 1.0 5 P23786 1 +Catalytic activity acting on a trna 0.2703791304122835 0.3935781496638201 0.6938925158679266 1.0 1.0 60 Q5T160,Q9NXH9,Q9BW92,Q6GMV3,Q15031,Q99575,Q9Y3E5,Q8TEA1,Q9NP81,Q9H974,Q9UGM6,Q5VV42 12 +Dna apurinic or apyrimidinic site endonuclease activity 0.4567571896515977 0.3807788868589341 0.7033673270061982 1.0 1.0 4 Q96FZ2,Q13686 2 +Oxidoreductase activity acting on nad p h 0.3394139878031421 0.3774404810484589 0.705846288114037 1.0 1.0 32 O95139,O75438,O43676,O95168,O75380,P28331,P03915,Q9P0J0 8 +Coreceptor activity 0.7386192342478074 0.3773024722379083 0.7059488351477343 1.0 1.0 2 Q13308 1 +Macromolecule transmembrane transporter activity 0.3494327136945737 0.376254396899275 0.7067277785306236 1.0 1.0 11 Q9NS69,Q07820 2 +Ribonuclease p rna binding 0.7359059391015946 0.370737959897134 0.7108327140702619 1.0 1.0 2 Q99575 1 +Single stranded dna binding 0.2696846936488196 0.3680520117310477 0.7128344521841847 1.0 1.0 62 P46100,P54132,Q15554,Q96SB8,Q7L590,Q9GZR2,Q8TAF3 7 +3 hydroxyacyl coa dehydrogenase activity 0.399446432429315 0.3639920913050052 0.7158639151215065 1.0 1.0 6 P40939,P55084 2 +Helicase activity 0.3193381208793845 0.3617134079737312 0.7175662064611883 1.0 1.0 94 Q9H2U1,Q9NY93,Q8N3C0,Q9UNY4,Q9NVP1,O75643,O60306,Q8IYB8,P28370,P33992,Q8NHQ9,Q8TDD1,Q7L2E3,Q6ZRS2,Q7Z478,Q9H6R0,Q9BQ39,Q7L014,Q9Y6V7,Q9NR30,Q14839,Q2NKX8,P13984,Q13206,Q92620,Q9H0S4,P46100,O00148,P54132,P0CG13,Q96GQ7,O60264,Q86XP3,Q9BUQ8,Q14527,Q8IX18,Q9NUL7 37 +Aldo keto reductase nadp activity 0.3687341089821936 0.3479443004378689 0.7278820145333704 1.0 1.0 8 Q9Y394,Q8TC12 2 +Phospholipase binding 0.4452488687782823 0.3457776059910935 0.7295098560666948 1.0 1.0 4 P84103,P20700,P07196 3 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.4082679541339706 0.3378176254530035 0.7355006267503466 1.0 1.0 5 P11802,P28482,Q00534,O60885 4 +Monocarboxylic acid binding 0.3457067841390272 0.3348534349948491 0.7377356496875176 1.0 1.0 16 Q96RQ3,P05165 2 +Insulin binding 0.7205305999397025 0.3346018653537048 0.7379254376001687 1.0 1.0 2 P08069 1 +Glycosaminoglycan binding 0.3447547436153503 0.3285472178080493 0.7424979490988488 1.0 1.0 17 P10586 1 +Rna methyltransferase activity 0.3391729058826391 0.3087587769056538 0.7575050291968948 1.0 1.0 23 Q9NXH9,P22087,Q8TEA1,Q9UNQ2,O43709,Q8IY81 6 +Nuclear receptor binding 0.2703427165010966 0.3074254443947175 0.7585195634686634 1.0 1.0 44 O15164,Q00403,O60244,P82094,P17096,Q8TDD1,Q96L73,Q969T9 8 +Integrin binding 0.3394058467760047 0.3066136373195187 0.7591374722497 1.0 1.0 19 Q9Y624,P11047 2 +Amino acid transmembrane transporter activity 0.3294903046369259 0.3063865043435813 0.7593103825806209 1.0 1.0 11 P08195 1 +Poly purine tract binding 0.3377813287829747 0.3046020508375773 0.7606692578632006 1.0 1.0 17 Q8TCS8,P31483 2 +Sulfate transmembrane transporter activity 0.7060596924932162 0.3023081137889544 0.7624171936326256 1.0 1.0 2 Q9UBX3 1 +Succinate transmembrane transporter activity 0.7060596924932162 0.3023081137889544 0.7624171936326256 1.0 1.0 2 Q9UBX3 1 +P53 binding 0.3344209200237547 0.2985921955690683 0.7652512209754947 1.0 1.0 25 Q9NZM5,P54132,P42858 3 +Cyclin dependent protein serine threonine kinase regulator activity 0.3664295767833163 0.2972987966629807 0.7662384002589329 1.0 1.0 7 P42574 1 +Ligase activity forming carbon nitrogen bonds 0.3362228149229771 0.2955591224936125 0.7675667950708527 1.0 1.0 21 Q8N2G8 1 +Aminoacyl trna editing activity 0.3236497897062737 0.2949227489410242 0.7680528933211854 1.0 1.0 10 Q9BW92,Q15031,Q5ST30,Q5JTZ9,P41252 5 +Dna polymerase binding 0.3223157657536796 0.2906731297871283 0.7713013239972539 1.0 1.0 10 Q15185,P36776,P51532,Q9H0A0 4 +Long chain fatty acyl coa binding 0.7006331022007841 0.2906440207891368 0.7713235889714392 1.0 1.0 2 O00154 1 +Mrna 3 utr binding 0.2375622712226373 0.2865624956577905 0.774447334638257 1.0 1.0 51 Q92879,Q13148,O76021,O43809,P16989,P62081,Q9Y6M1,Q01085,Q96B26,Q12906,Q06265,P31483 12 +Protease binding 0.3290453274296849 0.2843497436723134 0.7761423687151578 1.0 1.0 26 P42574,Q16186,P41440,P14174 4 +Protein transporter activity 0.3279084097101205 0.283543139920607 0.7767605169959388 1.0 1.0 14 Q9NS69,Q07820,Q99595,O14925,P08069 5 +Tfiid class transcription factor complex binding 0.3702944247105658 0.2719253904816872 0.7856793878169603 1.0 1.0 6 O60869,P22087 2 +Ubiquitin protein transferase regulator activity 0.3160495686597125 0.2712584266111308 0.7861922788570679 1.0 1.0 10 P60866,P62841 2 +P type transmembrane transporter activity 0.4182099757292727 0.2698092112705839 0.7873070359844012 1.0 1.0 4 P20020,P16615 2 +Pyrophosphate hydrolysis driven proton transmembrane transporter activity 0.3553795485384126 0.2640582891712129 0.7917350038647397 1.0 1.0 7 Q9UI12,Q9Y5K8,P21283 3 +Atpase coupled ion transmembrane transporter activity 0.3553795485384126 0.2640582891712129 0.7917350038647397 1.0 1.0 7 Q9UI12,Q9Y5K8,P21283 3 +Atpase activator activity 0.3172217112705311 0.2615527000224642 0.7936663146502179 1.0 1.0 12 O60884,P31689,P54709,Q5JTV8,Q8IXB1 5 +Membrane insertase activity 0.3521157875072784 0.2546430673756121 0.7989987924364468 1.0 1.0 7 Q8N766,Q9P0I2 2 +P type calcium transporter activity 0.6822429906542037 0.2529915269231915 0.8002747607994889 1.0 1.0 2 P20020 1 +Carbon carbon lyase activity 0.3220496904259336 0.2529268099933594 0.800324771515899 1.0 1.0 18 P38435,Q9UJ83,Q6P587,P30046,P23368 5 +C4 dicarboxylate transmembrane transporter activity 0.363254419713454 0.2516136574083105 0.80133970110957 1.0 1.0 6 Q9UBX3 1 +Dopamine receptor binding 0.3631521685262465 0.2513245178057883 0.8015632208911379 1.0 1.0 6 Q14344 1 +Acid thiol ligase activity 0.3083225981793183 0.2485842088644826 0.8036824246410885 1.0 1.0 10 Q4G176,Q9P2R7 2 +2 oxoglutarate dependent dioxygenase activity 0.3205029480149275 0.2461870638104035 0.8055374290345703 1.0 1.0 20 O60568 1 +Actin monomer binding 0.3611928003865213 0.2458168940003489 0.8058239787367387 1.0 1.0 6 P35080 1 +S adenosylmethionine dependent methyltransferase activity 0.2388268129800583 0.2449010617381704 0.8065330395729537 1.0 1.0 47 Q9NXH9,P22087,Q86VU5,O60725,Q96L73,Q8TEA1,Q9UNQ2,O43709,Q8IY81,P22061 10 +Ribonucleotide binding 0.2068301268262763 0.2448368228240324 0.8065827809644825 1.0 1.0 596 Q92614,P53365,P61006,Q96P47,Q969Y2,Q2NL82,Q8N3C0,Q8WVC6,Q8NI60,Q9UGM6,P41440,Q15382,Q9Y496,O60884,P31689,Q8NHQ9,P46013,Q7Z478,Q9BQ39,Q9BW92,Q9HCN4,Q9NR30,Q9UHD1,Q9NWH9,P31749,O43795,O75962,P19784,Q86Y07,Q92930,P05165,P54132,Q5ST30,Q96RQ3,P62330,Q96DE0,Q9BUQ8,Q9P2R7,P62820,Q9UIJ7,O15439,Q9H3P7,Q3LXA3,P11498,P61586,P40939,Q96I99,Q8NEB9,P46734,Q8IYB8,Q6UB35,O95140,Q9Y5S2,Q9NRA0,Q9UJ83,Q9UBF8,Q9Y285,Q8TDD1,P60953,P51153,Q9H6R0,Q96SB8,O95347,P08069,Q5T160,P15531,Q03518,P61160,Q4G0N4,Q16513,Q14839,Q2NKX8,Q16539,Q14344,Q13206,P84085,P20339,P61604,Q9H845,P46100,Q9Y6X9,Q96GQ7,Q5JTZ9,Q9UHY1,O60264,O96013,P12532,P61011,Q53H12,Q9NUL7,Q99986,Q9H2U1,Q9NY93,Q9UG63,Q9UNY4,Q9Y5M8,Q15257,Q15046,P52789,A6NHR9,O60306,O75695,P11388,P20020,P28370,Q9NP72,O75616,Q9Y6V7,Q15031,P51148,P13984,P17066,P78356,Q9BZG1,Q9NVJ2,O60333,P61019,Q9P0J0,Q15286,Q6PL18,Q9H0A0,Q9NVP1,P20338,O00159,Q13823,Q9H078,Q9NP81,Q92947,O95235,Q4G176,Q15120,Q92620,Q9H0S4,Q13308,Q9BZE4,Q03426,P35251,Q02880,Q96RP9,Q86XP3,Q14527 141 +Protein tag 0.676213445884821 0.2412923745435206 0.8093285205534304 1.0 1.0 2 Q9BZL1 1 +Vitamin b6 binding 0.31738207019038 0.2370796052278074 0.812595034051145 1.0 1.0 21 Q8TD30 1 +Single stranded rna binding 0.2589240505733147 0.2341486479265089 0.8148695798750429 1.0 1.0 43 O43347,Q8TCS8,Q15056,P09234,Q9UNP9,Q96KR1,P62487,Q12906,P31483 9 +Adenyl nucleotide binding 0.1732385282184747 0.2148264805324425 0.8299026063910837 1.0 1.0 490 Q92614,Q8N3C0,Q8WVC6,Q8NI60,Q9UGM6,P41440,Q9Y496,O60884,P31689,Q8NHQ9,P46013,Q7Z478,Q9BQ39,Q9BW92,Q9NR30,Q9UHD1,Q9NWH9,P31749,O43795,O75962,P19784,Q86Y07,P05165,P54132,Q5ST30,Q96RQ3,Q9BUQ8,Q9P2R7,Q9UIJ7,O15439,Q9H3P7,Q3LXA3,P11498,P40939,Q96I99,Q8NEB9,P46734,Q8IYB8,Q6UB35,Q9Y5S2,Q9NRA0,Q9UJ83,Q9UBF8,Q9Y285,Q8TDD1,Q9H6R0,Q96SB8,O95347,P08069,Q5T160,P15531,Q03518,P61160,Q4G0N4,Q16513,Q14839,Q2NKX8,Q16539,Q13206,P61604,Q9H845,P46100,Q9Y6X9,Q96GQ7,Q5JTZ9,Q9UHY1,O60264,O96013,P12532,Q53H12,Q9NUL7,Q99986,Q9H2U1,Q9NY93,Q9UG63,Q9UNY4,Q15257,Q15046,P52789,A6NHR9,O60306,P11388,P20020,P28370,Q9Y6V7,Q15031,P13984,P17066,P78356,O60333,Q9P0J0,Q6PL18,Q9H0A0,Q9NVP1,O00159,Q9H078,Q9NP81,Q92947,O95235,Q4G176,Q15120,Q92620,Q9H0S4,Q13308,Q03426,P35251,Q02880,Q86XP3,Q14527 109 +Rna polymerase ii c terminal domain phosphoserine binding 0.6593307205305945 0.2102781872161658 0.8334505587767056 1.0 1.0 2 Q92541 1 +Ligase activity forming phosphoric ester bonds 0.3924585218702887 0.2065301256163481 0.8363768351161225 1.0 1.0 4 P18858,Q9Y3I0,P49916 3 +Poly a binding 0.2962566264427783 0.200387231047749 0.8411777451120588 1.0 1.0 13 P31483 1 +Calcium ion transmembrane transporter activity 0.2933154329901104 0.1979034746897158 0.8431205855381931 1.0 1.0 12 P20020,Q9UM00,Q8NE86,P08195,O95202,P16615 6 +Translation initiation factor activity 0.2734672823845878 0.1963067776690507 0.8443700567900385 1.0 1.0 37 Q9UI10 1 +Small ribosomal subunit rrna binding 0.3412916094772014 0.1935350763316723 0.8465399383565171 1.0 1.0 6 P82912 1 +Isomerase activity 0.2447909050273084 0.1929359997893752 0.8470090909242094 1.0 1.0 70 Q96JJ7,P26885,Q96BP3,O95394,Q96C23,P42126,Q9Y237,P30405,P14174,Q9H2H8,P45877,Q15125 12 +Protein containing complex binding 0.1716566519136924 0.1906210912505996 0.848822464756062 1.0 1.0 404 O43491,Q92614,P22087,O15020,Q9Y3A5,Q9Y496,Q07021,P11047,O15143,O94906,P10586,P50995,Q13576,Q7Z478,P07305,P17655,P05114,O43795,P04439,P08579,Q96BK5,Q5SW96,Q8N122,Q49A26,Q16795,Q9Y613,Q14137,O00541,O14654,P16403,Q15554,Q9Y624,P46939,P40939,P10412,Q9NQ48,Q9Y5S2,Q66K74,P57678,Q9UBG0,O00487,O95202,Q9H6R0,P08069,P14923,P15531,P61160,Q9BSH4,Q5MNZ6,Q14839,P16989,P62314,P78536,O95400,O75367,Q12824,P04844,Q00325,Q9GZN1,Q9BT73,Q5SSJ5,P09012,O15144,O75616,Q92522,Q9UHB6,Q9Y281,P28289,Q16186,Q9UII2,P16402,P42574,P62750,Q96ST3,Q9BY77,O00159,Q15056,Q96EY7,Q9BUN8,Q9BY44,P60468,P05204,O75083,Q04323 84 +Cyclin dependent protein kinase activity 0.3542546771273333 0.1894394662814952 0.8497483948140421 1.0 1.0 5 P11802,Q00534,P06493,Q00535 4 +Actin filament binding 0.2485700145013284 0.1824117140833756 0.8552596335206548 1.0 1.0 75 Q9UHB6,Q9Y281,Q92614,O15144,P28289,Q13576,O15020,Q9Y613 8 +Nucleobase transmembrane transporter activity 0.6400361772686035 0.1780397943079852 0.858691723627167 1.0 1.0 2 P05141 1 +Oxidative phosphorylation uncoupler activity 0.6400361772686035 0.1780397943079852 0.858691723627167 1.0 1.0 2 P05141 1 +Complement component c1q complex binding 0.6388302683147301 0.1761397150100676 0.8601841805927499 1.0 1.0 2 Q07021 1 +Protein phosphatase binding 0.2495475458161605 0.1746133140877395 0.8613834861875467 1.0 1.0 41 Q86XL3,Q9NWH9,Q16539,Q96QC0,Q5H9R7 5 +Translation factor activity rna binding 0.2161313860703363 0.1729899263333964 0.8626593458690106 1.0 1.0 55 Q9UI10 1 +Lyase activity 0.2150668348616957 0.1657786515080199 0.8683311472619075 1.0 1.0 56 A1L0T0,P53701,P22830,Q04760,P38435,Q3LXA3,Q9UJ83,P42126,Q6P587,P30046,P40939,Q99798,Q7Z7K6,P23368,P55084 15 +Tat protein binding 0.3411712500670461 0.1605655182921262 0.8724356148681018 1.0 1.0 5 P31689,Q12824,P06748 3 +Hydrolase activity acting on acid anhydrides 0.2549440418339802 0.1581453450208348 0.8743422700057448 1.0 1.0 288 Q92614,Q15286,Q9BRJ7,P61006,Q96P47,Q969Y2,Q2NL82,Q9NY93,Q8N3C0,Q96T23,Q6PL18,Q9H2U2,Q9NVP1,P41440,Q15382,P20338,O95140,Q9NP72,Q13823,Q8NHQ9,Q8TDD1,P60953,P51153,Q9H078,Q7Z478,Q9BW91,Q9H6R0,O95235,Q9Y6V7,P35080,P51148,Q92620,Q2NKX8,P13984,P17066,Q9H0S4,P20339,Q9BZE4,Q9BZG1,P35251,Q92930,Q9NVJ2,P46100,P54132,Q96GQ7,Q96RP9,P62330,O60333,Q86XP3,P61019,Q14527,P62820,Q9NUL7,Q9UIJ7 54 +Androgen receptor binding 0.2745247611033987 0.1579338869498431 0.8745088952289992 1.0 1.0 12 P82094 1 +Disordered domain specific binding 0.27832886012141 0.1556654871329074 0.876296702755798 1.0 1.0 15 Q9Y3C6,O94973,P04406 3 +Hydro lyase activity 0.2793539669522049 0.1552440573672556 0.876628916537026 1.0 1.0 16 P42126,Q99798,P40939,P55084 4 +Catalytic activity acting on a nucleic acid 0.3022374257460727 0.1536830372674628 0.8778596601771946 1.0 1.0 272 Q92614,P22087,Q8N3C0,Q9UGM6,P41440,O15446,O95391,P46087,Q8NHQ9,Q96B26,Q7Z478,Q9BQ39,Q9BQP7,Q9BW92,Q13868,Q9NR30,Q99575,P54132,Q5ST30,Q96DE0,Q9BUQ8,Q13503,Q6GMV3,Q9BRJ7,P24928,Q15554,Q8IYB8,O15160,Q9GZS1,Q9Y285,Q66K74,Q8TDD1,Q12972,O43709,Q9H6R0,P15531,Q5T160,P52758,Q9Y2S7,Q14839,Q2NKX8,Q13206,Q9H9Y6,Q9H974,Q9Y2L1,P46100,Q96GQ7,Q5JTZ9,O60264,O95602,Q6P6C2,P62487,Q8IY81,Q9NUL7,Q9H2U1,Q9NY93,Q8TEA1,Q9UNY4,Q5VV42,Q15046,O60306,P11388,P28370,Q8TCS8,P33992,Q7L014,Q15185,Q9NXH9,Q9Y6V7,Q15031,Q9Y3I0,Q9BV44,P13984,O00148,P11387,P18887,P0CG13,P19388,Q5RKV6,P78346,Q9H9L3,Q9NVP1,Q9NP81,O60832,P62875,Q92620,Q9H0S4,Q9UNQ2,Q9Y2P8,P35251,Q02880,Q86XP3,Q9Y3E5,Q14527,Q06265 95 +Guanyl nucleotide binding 0.3031239332636744 0.1505928341747486 0.8802969144252091 1.0 1.0 129 P53365,Q15286,P61006,Q96P47,Q969Y2,P41440,Q15382,P20338,O75695,O95140,Q9NP72,Q13823,O75616,P60953,P51153,P51148,P20339,P78356,Q9BZE4,Q9BZG1,Q92930,Q9NVJ2,Q96RP9,P62330,P61019,P62820,Q9UIJ7 27 +Structural molecule activity 0.3791480812631793 0.1493516051143685 0.8812761968625795 1.0 1.0 220 Q7Z7F7,O43491,P83731,Q5T653,Q02878,P62424,P61513,P18077,P82914,Q9Y3U8,P50914,P37198,P62701,P62280,P62269,P62750,P62857,Q9Y3D3,O15020,P49790,P39019,Q9BYD6,Q9UHA3,P82912,P11047,O15143,Q9Y3D9,Q99797,P62277,O15144,P46776,P62081,Q5SRE5,Q9BTX1,P14923,P26373,P63173,P61160,P62841,P61353,P36578,Q09666,P62910,P62847,P82675,Q8N983,Q9H2W6,P83881,P62899,Q9Y2R9,P84098,P39023,P32969,P60866,P62917,P49406,Q6DKI1,P47914,P17096,Q92665,Q8NFH5,P61313,Q9NX20,P62244 64 +U2 snrna binding 0.3351442271462197 0.148253304368093 0.8821428657530062 1.0 1.0 5 Q15393,Q6P2Q9 2 +Ligase activity forming carbon oxygen bonds 0.261785437115682 0.1479532800377531 0.8823796394745418 1.0 1.0 34 Q5T160,Q9BW92,Q15031,Q5ST30,Q5JTZ9,Q9Y285,Q9NP81,Q9UGM6 8 +3 5 exonuclease activity 0.2730193627909557 0.1441637492718531 0.8853711657580494 1.0 1.0 27 Q9H9L3,Q9GZR2,Q8TCS8,Q13868 4 +Cell adhesion molecule binding 0.1934130996161438 0.1436432478065462 0.8857821879594718 1.0 1.0 236 O60664,P83731,P53365,Q02878,P62424,P62750,Q09666,Q9Y624,O15020,Q14126,O14530,P11047,P43487,Q15056,O15446,P10586,Q7Z478,Q92522,Q8WU90,O76021,Q9UHB6,Q13492,Q9BY44,Q01970,Q13308,Q9BY67,P78536,Q9UBC2,Q9UGI8,P47914,P35613,Q07960,P61313,P08195,P62820,P22061 36 +General transcription initiation factor binding 0.2747839856312105 0.1421519327506741 0.8869599982333922 1.0 1.0 20 Q9ULM3,Q00403,P22087,O15160,Q9GZS1,Q8N122,O60869 7 +Atp dependent activity 0.2259476980684972 0.141693452544204 0.8873221468729302 1.0 1.0 229 P21283,Q92614,Q9H2U1,O15439,Q9NY93,Q8N3C0,Q96T23,Q9UNY4,Q6PL18,Q9NVP1,P41440,A6NHR9,O60306,Q9Y496,Q8IYB8,P11388,P20020,P28370,O00159,Q8NHQ9,Q8TDD1,Q9H078,Q7Z478,O95347,Q9H6R0,Q9BQ39,O95235,Q9Y6V7,P35080,Q9NR30,Q03518,Q4G176,Q14839,Q2NKX8,P13984,Q13206,P17066,Q92620,Q9H0S4,P61604,O43795,P35251,P46100,Q9Y6X9,P54132,P0CG13,Q96GQ7,Q02880,O60333,O60264,Q86XP3,Q9BUQ8,Q9Y5K8,Q14527,Q9NUL7,Q9UIJ7 56 +Ribonucleoprotein complex binding 0.2563065018785883 0.1396649109487887 0.8889247516195165 1.0 1.0 96 Q14137,O00541,P04844,P09012,Q9Y3A5,Q07021,Q15056,O94906,Q96EY7,O75616,Q9BUN8,P57678,Q7Z478,O95202,Q9H6R0,Q9BSH4,Q9BY44,P16989,P62314,P08579,P60468,O95400 22 +Peptide hormone receptor binding 0.6119987940910395 0.137366249374843 0.890741307214252 1.0 1.0 2 Q06124 1 +Hormone receptor binding 0.6119987940910395 0.137366249374843 0.890741307214252 1.0 1.0 2 Q06124 1 +Cadherin binding 0.1785744069937318 0.1364037048790054 0.8915021449845708 1.0 1.0 210 O60664,P83731,P53365,Q02878,P62424,P62750,P50914,Q09666,Q9Y624,O15020,Q14C86,O00567,O14530,P43487,Q15056,O15446,Q06124,P61026,Q9P0L0,P62854,P62136,Q7Z478,Q92522,P14923,Q8WU90,O76021,P35241,Q9UHB6,Q16513,Q13492,Q9BY44,Q01970,O43795,Q9H444,Q9UBC2,Q9UGI8,P47914,P35613,O96013,Q07960,P25685,P61313,P08195,P62820,P22061 45 +Aldehyde lyase activity 0.3289076644538239 0.1361752543263489 0.8916827371070206 1.0 1.0 5 O95470,P04075,Q9UJ83,P09972 4 +Udp glucosyltransferase activity 0.3149548613275755 0.1351125038768327 0.8925229241694437 1.0 1.0 6 Q7Z4H8,Q9Y673 2 +Amino acid binding 0.2612455958149527 0.1349511746561136 0.8926504780635036 1.0 1.0 12 Q15046,Q5JTZ9,P34896 3 +Catalytic activity acting on rna 0.3231212983776914 0.1344359944854795 0.8930578204763757 1.0 1.0 193 P22087,Q9UGM6,O15446,O95391,P46087,Q8NHQ9,Q96B26,Q7Z478,Q9BQ39,Q9BW92,Q13868,Q9NR30,Q99575,Q5ST30,Q96DE0,Q9BUQ8,Q13503,Q6GMV3,Q9BRJ7,P24928,Q8IYB8,O15160,Q9GZS1,Q9Y285,Q8TDD1,Q12972,O43709,Q9H6R0,Q5T160,P52758,Q13206,Q9H9Y6,Q9H974,Q9Y2L1,Q96GQ7,Q5JTZ9,O95602,Q6P6C2,P62487,Q8IY81,Q9NUL7,Q9H2U1,Q9NY93,Q8TEA1,Q5VV42,Q15046,O60306,Q8TCS8,Q7L014,Q9NXH9,Q9Y6V7,Q15031,Q9BV44,Q9Y3I0,O00148,P19388,Q5RKV6,P78346,Q8IX18,Q9H9L3,O15091,Q9NVP1,O75643,P19387,P49642,P39748,Q7L2E3,Q9NP81,Q96RS0,P62875,Q92620,Q9H0S4,Q9UNQ2,Q9Y2P8,Q86XP3,Q9Y3E5,Q06265 77 +Proton transmembrane transporter activity 0.2506977777140217 0.1335990819324192 0.893719610192967 1.0 1.0 35 O14548,P20674,P05141,P56134,P21283,Q00325,P48047,Q9Y5K8,Q9UDW1 9 +Mrna binding 0.298524029787963 0.1309839773731478 0.8957879823992088 1.0 1.0 187 Q96T37,P83731,P09234,Q86V81,Q8NHU6,Q9Y3Y2,Q9BY77,P82912,P31483,Q13247,Q07021,A0AV96,P62277,P08621,Q9Y5A9,P51608,P52272,P62081,Q12972,Q96B26,Q92879,Q01085,Q9H6R0,P33240,O76021,Q13148,Q9BSH4,O43809,Q9BY44,P16989,Q9Y2R9,O75152,P34896,Q8NI27,Q15637,Q06265 36 +Phospholipase c activity 0.3969358976498424 0.130225153932941 0.8963882940727359 1.0 1.0 3 Q01970 1 +Atp hydrolysis activity 0.257352437131855 0.126807642867791 0.8990926464421545 1.0 1.0 175 Q92614,Q9H2U1,Q9NY93,Q8N3C0,Q96T23,Q6PL18,Q9NVP1,P41440,A6NHR9,O60306,Q9Y496,Q8IYB8,P20020,Q8NHQ9,Q8TDD1,Q9H078,Q7Z478,O95347,Q9H6R0,Q9BQ39,O95235,Q9Y6V7,P35080,Q9NR30,Q14839,Q2NKX8,P13984,Q13206,P17066,Q92620,Q9H0S4,P61604,P35251,P46100,Q9Y6X9,P54132,Q96GQ7,O60333,O60264,Q86XP3,Q9BUQ8,Q9NUL7,Q9UIJ7 43 +Chromatin binding 0.1803607526125251 0.1255577274886454 0.9000820266353609 1.0 1.0 171 O15164,O75367,Q12824,Q92769,P16403,P16402,P24928,Q9UQR0,P37198,Q9GZN1,Q96L73,Q15233,Q96ST3,Q6PL18,Q5SSJ5,Q9H0U9,P06748,Q15022,P10412,P11388,Q00403,P28370,Q8WTT2,P34897,Q9UBU8,P51608,P82979,Q8TAQ2,Q7L2E3,Q92522,O95347,Q15424,P07305,Q13185,Q04837,Q9Y5B9,Q13330,O43809,Q14839,P05114,Q00839,O60216,Q6UXN9,O94776,P17480,P05204,P46100,Q9Y6X9,P11387,Q9P0M6,Q02880,O60264,P17096,Q969T9,O95602,P28340,P67870,Q00059,Q49A26 59 +Long chain fatty acid transporter activity 0.3901598768614583 0.1199886933852685 0.9044921046176232 1.0 1.0 3 P28288 1 +S100 protein binding 0.2791640625871899 0.1196404951844089 0.9047679395826916 1.0 1.0 8 Q09666 1 +Cell adhesion mediator activity 0.2578022852179256 0.1176877395044817 0.9063150817228298 1.0 1.0 20 P61026,P35613,P15924,Q08722,O96013,P62136,Q14126,P14923 8 +4 iron 4 sulfur cluster binding 0.2577043257126319 0.1173500053742274 0.9065827001773754 1.0 1.0 21 Q5VV42,P28331,Q99798 3 +Translation regulator activity nucleic acid binding 0.1991313954802666 0.1157589789000704 0.907843561980204 1.0 1.0 65 Q9UI10,Q7Z478 2 +Gtpase binding 0.2362072449877018 0.1153999985313631 0.908128080127078 1.0 1.0 103 P53365,Q9HD47,Q9Y5S2,O14641,Q07960,Q9UJY5,Q13576,Q9NX47,P16989 9 +Phosphofructokinase activity 0.3869119420989164 0.1152969081675203 0.9082097889458172 1.0 1.0 3 P08237,P17858 2 +Fructose 6 phosphate binding 0.3869119420989164 0.1152969081675203 0.9082097889458172 1.0 1.0 3 P08237,P17858 2 +Extracellular matrix binding 0.3438714344781365 0.1138087049650444 0.909389437868938 1.0 1.0 4 O94813 1 +Catalytic activity acting on dna 0.2193437420905664 0.1117048477956962 0.9110574354058184 1.0 1.0 91 Q92614,Q9H2U1,Q15554,Q8N3C0,Q9UNY4,P41440,Q8IYB8,P11388,P28370,P33992,Q66K74,O60832,P15531,Q9BQP7,Q15185,Q9Y2S7,Q14839,Q2NKX8,P13984,P35251,P46100,P54132,P11387,P18887,P0CG13,Q02880,O60264,Q14527 28 +Exoribonuclease activity 0.2506162485578587 0.1116867756067124 0.9110717652577144 1.0 1.0 26 Q8TCS8,Q13868,Q5RKV6,Q9H9L3,Q06265 5 +Rna polymerase ii specific dna binding transcription factor binding 0.2150973587680573 0.1107843128547605 0.9117873852993286 1.0 1.0 88 O15164,Q12824,P09874,O60244,Q96L73,Q96ST3,Q00403,P31689,P42771,O94906,Q8TDD1,Q9NPF5,Q13330,Q16539,P82094,P78347,Q86UE4,P17096,Q969T9,Q06265 20 +Actin binding 0.2050914809786008 0.1106847710891097 0.91186632268004 1.0 1.0 116 Q8N8S7,P35080,Q92614,Q13576,O15020 5 +Double stranded rna binding 0.2263944670082754 0.1099821241431458 0.9124235517696372 1.0 1.0 37 Q8IYB8,Q15056,Q9NR30,Q9H2U1,Q12905,Q86UE4,Q9NY93,Q96KR1,Q7L2E3,O95793,Q12906,P08195,Q9H6R0 13 +Small protein activating enzyme binding 0.3826899879372777 0.1094048272878082 0.9128814051117884 1.0 1.0 3 Q9UBE0,Q9UBT2 2 +Ligase activity 0.1965372431356248 0.105892233540879 0.915667856158874 1.0 1.0 95 Q5T160,Q9NP81,Q6UB35,P05165,Q9BW92,Q15031,P56134,Q5ST30,Q96RQ3,Q9P2R7,Q4G176,P48047,P11498,Q96I99,Q9UGM6,Q8N2G8 16 +Iron ion binding 0.2428827575159319 0.1049783734850769 0.9163929693433936 1.0 1.0 27 O60568,Q9UMS0,Q99798 3 +Heat shock protein binding 0.1718450548643603 0.1048100102120849 0.9165265668014766 1.0 1.0 52 Q8WXX5,Q15185,O60884,Q02218,Q9UHD1,P31689,P37198,Q07812,Q9NZJ4,P17066,P25685,P42858,Q00059,Q8IXB1 14 +Cell cell adhesion mediator activity 0.2451522320963771 0.104588279958004 0.9167025149359656 1.0 1.0 18 P61026,P35613,O96013,Q08722,P62136,Q14126,P14923 7 +Rna polymerase ii activity 0.583358456436526 0.1032752462743233 0.917744521163234 1.0 1.0 2 P24928 1 +Oxidoreductase activity acting on a sulfur group of donors 0.2360251442976818 0.1014351547649225 0.919205030912286 1.0 1.0 29 Q96JJ7,P30048,P09622,Q9Y320,O43819,O43396,Q8IXB1,P13667 8 +Metal cluster binding 0.2279825145773662 0.0996850469385957 0.9205943722195576 1.0 1.0 32 P22830,P28331,Q5VV42,Q99798,Q9UMS0 5 +Disulfide oxidoreductase activity 0.2352918632594799 0.0968876073566652 0.9228156504000742 1.0 1.0 25 Q96JJ7,Q9Y320,O43819,O43396,Q8IXB1,P13667 6 +Snap receptor activity 0.2302658351533284 0.0955085161348745 0.9239109262864986 1.0 1.0 13 O75396,Q9UNK0,Q86Y82,P51809,O15400 5 +Cobalamin binding 0.3719688613574934 0.0954806185202399 0.9239330841009092 1.0 1.0 3 P22033 1 +Vinculin binding 0.3031931905748717 0.093468514412078 0.9255313620260484 1.0 1.0 5 P46939 1 +Proteasome binding 0.2276717811238733 0.0933160765311625 0.9256524605862038 1.0 1.0 13 O00487,Q16186 2 +Dna helicase activity 0.1752125552122587 0.0896601531342092 0.9285572815504904 1.0 1.0 41 P54132,P46100,Q2NKX8,P13984 4 +Microfilament motor activity 0.2580298705427616 0.0896390051347951 0.928574087541566 1.0 1.0 8 O00159 1 +Ubiquitin ubiquitin ligase activity 0.3257918552036221 0.0884170637840536 0.9295451994712828 1.0 1.0 4 P61086,Q9UNE7,Q9UMS4 3 +Spectrin binding 0.2877854670863901 0.0881251552256454 0.9297772031774818 1.0 1.0 6 O43491 1 +Alditol nadpplus 1 oxidoreductase activity 0.5679831172746388 0.0879629806614739 0.9299060992034364 1.0 1.0 2 P15121 1 +Nad retinol dehydrogenase activity 0.5679831172746366 0.0879629806614717 0.9299060992034384 1.0 1.0 2 Q8TC12 1 +Ribosome binding 0.1368607122871008 0.0876231338935301 0.9301762147089268 1.0 1.0 43 P04844,Q9BSH4,Q9BY44,P60468,Q9Y3A5 5 +Damaged dna binding 0.2078037498820421 0.0872835040334981 0.9304461658486748 1.0 1.0 31 Q96SB8,P54132 2 +Structural constituent of nuclear pore 0.2213756575480474 0.0860931259446643 0.9313923880382088 1.0 1.0 19 Q5SRE5,Q8NFH5,P37198,Q9BTX1 4 +Thiol oxidase activity 0.359469240048263 0.0810837208474248 0.9353753719373225 1.0 1.0 3 P07237,Q96HE7 2 +Protein folding chaperone 0.1816524908870016 0.0779399116267538 0.9378758510684492 1.0 1.0 27 P40227,Q14318,O60925,Q96A33,P17987,P04792,P48723,P50991,P48643,Q0VDF9,P08238,P27797,P54652,P50990,Q99832,P17066,Q9UHV9,P0DMV9,O00273,P07900,P25685,P11142,P49368,O14967,P38646,P78371 26 +Metal ion transmembrane transporter activity 0.1979840536642667 0.0773065647386334 0.938379668632142 1.0 1.0 21 P20020,Q9UM00,Q8NE86,Q96ER9,P08195,O95202,Q00535,P16615 8 +Metal dependent deubiquitinase activity 0.2635739213476976 0.0760672529857398 0.9393655929641378 1.0 1.0 7 O00487,O00303,Q6P2Q9 3 +Fibronectin binding 0.5538136870666162 0.0756030578377061 0.9397349036269572 1.0 1.0 2 P05556 1 +Atpase coupled cation transmembrane transporter activity 0.195144781562336 0.0747250599451968 0.94043346845925 1.0 1.0 13 P20020,P21283,Q9UI12,Q9Y5K8,P36543,P16615 6 +Carbon oxygen lyase activity 0.1794738450558675 0.0737679924554864 0.9411949959307576 1.0 1.0 21 Q99798 1 +Sirna binding 0.3103747233649825 0.0705046288899216 0.9437920163994666 1.0 1.0 4 P51608,Q9UPY3 2 +Tbp class protein binding 0.2339800789160681 0.0655397868260367 0.9477442291092262 1.0 1.0 8 Q9ULM3,Q9Y265,Q00403,P62191 4 +Serine transmembrane transporter activity 0.3046757164404244 0.0647134040087428 0.9484021903385944 1.0 1.0 4 Q96QD8,Q96NB2,Q9H9B4 3 +Sulfotransferase activity 0.5296955079891372 0.0581640738762874 0.953617937146964 1.0 1.0 2 Q8NCH0 1 +Peptide lysine n acetyltransferase activity 0.1902208268588151 0.0579968349408726 0.9537511496362948 1.0 1.0 9 Q9GZZ1 1 +Supercoiled dna binding 0.2724184107986204 0.056744463565788 0.9547487542505024 1.0 1.0 5 O75475 1 +Acetyl coa c acyltransferase activity 0.2065709720109845 0.0488113846551908 0.9610696093476534 1.0 1.0 8 P40939,P55084 2 +Sumo ligase activity 0.5116068736810239 0.0477912187787927 0.9618826349605218 1.0 1.0 2 Q96MF7 1 +Molybdopterin cofactor binding 0.5058788061501239 0.0449451192211107 0.9641510532224312 1.0 1.0 2 Q9NQX3 1 +Histone methyltransferase binding 0.248894399179251 0.04321166065662 0.965532809912174 1.0 1.0 6 Q13185,O00567 2 +G protein beta subunit binding 0.4880916490804818 0.0373249637712462 0.9702259011469884 1.0 1.0 2 P63218 1 +Thioredoxin disulfide reductase activity 0.4630690382875925 0.0293356489126659 0.9765968954080356 1.0 1.0 2 Q6DKJ4 1 +Phosphodiesterase i activity 0.4386493819716547 0.024020019424997 0.9808366401212713 1.0 1.0 2 P27695 1 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.4305094965330042 0.0226862057347372 0.98190057923421 1.0 1.0 2 Q13686 1 +1 acylglycerophosphocholine o acyltransferase activity 0.3807657521857093 0.0178603096151065 0.9857502922982512 1.0 1.0 2 P30041 1 +Cdp alcohol phosphatidyltransferase activity 0.3705155260777766 0.0173650834426184 0.9861453643295256 1.0 1.0 2 O14735 1 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..726b5efcf5d1bceb5a471c4a1c749f9b72f51d6d --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 1 adaptor complex binding", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Basal transcription machinery binding", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Bile acid transmembrane transporter activity", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor activity", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Fatz binding", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione hydrolase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "Hypoglycin a gamma glutamyl transpeptidase activity", "I smad binding", "Identical protein binding", "Immune receptor activity", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interferon receptor activity", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Mechanosensitive ion channel activity", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein hormone receptor activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding"], "available_proteins": ["AACS", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATRX", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C1orf50", "C20orf27", "C2CD5", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDR2L", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPV", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT7", "CNOT9", "CNP", "COASY", "COG2", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAHD1", "FAM118B", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GID4", "GID8", "GIGYF2", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOPC", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFKB1", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE1", "SYNE2", "TAB1", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM30A", "TMEM43", "TMEM59", "TMEM63A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TTC1", "TTC26", "TTC28", "TTC4", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS18", "VPS25", "VPS33B", "VPS35", "VPS37C", "VPS4A", "VPS4B", "VRK1", "VRK2", "VTA1", "VTI1B", "WARS", "WARS2", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABT1", "ACAD9", "ACBD3", "ACO2", "ACOT7", "ACSF3", "ACTR2", "ACTR6", "ADAM17", "ADRM1", "AGAP3", "AGK", "AHNAK", "AK3", "AKAP12", "AKAP8L", "AKAP9", "AKR1B1", "AKT1", "ALDH4A1", "ALDH6A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH1", 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1.0882965742387771 1.0765869657248284 0.9224773457089386 0.2739378776344282 0.0010343090391069 0.004071454093033 0.0236659942035878 0.0832040423996277 +Aplasia hypoplasia of the capital femoral epiphysis 2 6 2.372426348318014 0.017671685965634 1.4344660194174756 5.019417475728155 0.4404435176817264 0.4586115848866851 1.1692153440192188 1.5902041300501577 0.9972055316061226 0.3108875242391429 2.3666612945957126e-05 0.000188873280149 0.0027195691326621 0.0185110547795427 +Absent epiphyses 2 7 2.3708709288563528 0.0177462270931008 1.6601941747572817 6.019417475728155 0.3808059139538731 0.4787450056067535 1.354986461855146 1.5902041300501577 0.9446543923619232 0.3021365086610809 3.066034551708988e-05 0.0002437892001771 0.0034718672031755 0.0232044770208039 +Leukodystrophy 16 61 2.279895092552731 0.0226139111948595 14.718446601941748 56.94174757281554 0.1148532598751742 0.5363986626245857 6.478744148544089 5.4693767819453125 1.1351385962972955 0.354727749313835 0.0128572972549243 0.074977025310764 0.0113498749706627 6.320859092189801e-06 +Deformed sella turcica 1 5 2.2429784811238487 0.0248982021919024 1.449029126213592 4.361650485436893 0.6519584745232953 0.4108786670869809 1.0702617541763486 1.191712968868623 0.98030484078304 0.3007326817007539 0.0015075035399645 0.0058956460302812 0.0336123253792317 0.1144905971504207 +Increased csf lactate 16 53 2.222669387509886 0.026238101576586 14.563106796116504 50.03398058252427 0.4527108683296134 0.4236743568986457 6.839235611227043 5.521257303659666 1.4241114192986506 0.3526497741057939 0.0093752195011205 0.0112616954341839 0.006121125347197 1.1889409738409136e-06 +Abnormal breath sound 3 11 2.142528818870153 0.0321509521783833 3.8033980582524274 10.140776699029129 -0.6239174994173038 0.4468361447627028 2.030755779438873 1.937014863444428 0.9002992493231876 0.3047688169529696 0.2067156970649581 0.3714211816154574 0.3208944456062105 0.1976251561793972 +Difficulty standing 2 6 2.1188115796929465 0.034106393745648 1.7766990291262137 5.140776699029126 0.104137574144315 0.5487370906701988 1.2555278844533218 1.0903759833599294 0.905612577655904 0.3040648656866173 0.0010343090391069 0.004071454093033 0.0236659942035878 0.0108623726931483 +Abnormal activity of mitochondrial respiratory chain 16 59 2.1168733507988056 0.0342705979387119 14.847087378640778 52.86407766990291 0.7821137838412346 0.382257667326437 7.203923975365814 5.31995427327111 1.5049815702887546 0.3635380021892623 0.0102615341834231 0.0615174189559832 0.0753163213979132 8.740367690818418e-06 +Neuronal loss in basal ganglia 2 5 2.111924224062284 0.0346929492658496 1.5655339805825244 4.805825242718447 0.2483177791560154 0.5917175153512315 1.1587893147720107 0.9634913497849256 0.7904867027469618 0.2911868526997075 1.0 0.0758460972151271 0.1801790130745941 0.0054555274430988 +Acute leukemia 22 52 2.020262774172204 0.0433561379514779 17.990291262135923 45.95145631067961 -0.7182027726172646 0.4725613598893733 7.413573415631141 3.981458582261782 1.0745726377594105 0.3501093912531572 0.3491693980885609 0.2099579933724119 0.0198212558192573 0.001046492080673 +Limitation of knee mobility 0 5 2.0068396149599788 0.0447667432274259 2.6019417475728157 5.410194174757281 -0.5617110046481407 0.4402655246098155 1.4487343376453374 1.4810102040269966 0.9469021939248464 0.3007110179569926 0.0937235599037543 0.179062604831997 0.3916284783790085 0.634541793783965 +Subcapsular cataract 0 7 1.9779108905604303 0.047938760150914 1.953883495145631 6.609223300970874 -0.0461103410312459 0.5642011957638476 1.5344932011856134 1.2268090975319517 0.8166435103533282 0.2756601408786855 0.1201219647894398 0.2263045436956677 0.4759945765538561 0.7299045962681672 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d33ae5b038e5385607c7adff584bf6c60f4c1355 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 4653, + "title": "Average number of proteins per term", + "value": 24.917472598323663 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..08d9fe4fe4d94a9aaef73a458d93ca037fbcf2c9 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a3e26d1276927e1dd87b1cee643004884eda7011 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1303 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Limited wrist movement 0.8911591544282786 2.4425909931783885 0.0145822530502659 1.0 1.0 6 Q9H6K4 1 +Aplasia hypoplasia of the capital femoral epiphysis 0.8739115343639174 2.372426348318014 0.017671685965634 1.0 1.0 6 Q7RTS9,O43909 2 +Absent epiphyses 0.8444459933994286 2.3708709288563528 0.0177462270931008 1.0 1.0 7 Q7RTS9,O43909 2 +Leukodystrophy 0.4667843140206301 2.279895092552731 0.0226139111948595 1.0 1.0 61 P19404,Q8TCS8,O43676,O15160,Q9BSH4,Q86Y39,O43819,Q8IUX1,Q969Y2,P11498,O75380,P08559,P28331,Q9NPL8,Q96CU9,Q9P0J0 16 +Deformed sella turcica 0.8703748523089284 2.2429784811238487 0.0248982021919024 1.0 1.0 5 Q7RTS9 1 +Increased csf lactate 0.4443734334374702 2.222669387509886 0.026238101576586 1.0 1.0 53 Q5T160,Q8TCS8,O43676,P03915,Q9BSH4,Q86Y39,O43819,Q96CU9,Q8IUX1,O75380,P08559,P28331,Q9NPL8,Q8NI60,P30038,Q9P0J0 16 +Abnormal breath sound 0.702253870246361 2.142528818870153 0.0321509521783833 1.0 1.0 11 Q86TI2,P57076,Q969Y2 3 +Difficulty standing 0.8126981630552087 2.1188115796929465 0.034106393745648 1.0 1.0 6 Q7RTS9,Q9UGM6 2 +Abnormal activity of mitochondrial respiratory chain 0.4468666955570214 2.1168733507988056 0.0342705979387119 1.0 1.0 59 P20674,P19404,O43676,Q9BSH4,Q86Y39,Q8IUX1,Q969Y2,Q96EY7,O75380,Q9P0J0,P08559,P28331,Q9NPL8,Q96CU9,Q5T440,Q9UMS0 16 +Neuronal loss in basal ganglia 0.8383438141864523 2.111924224062284 0.0346929492658496 1.0 1.0 5 P42858,Q99986 2 +Chronic sinusitis 0.8840021142167824 2.054524490446249 0.0399249555328578 1.0 1.0 4 Q03518,P57076 2 +Acute leukemia 0.4230284123830748 2.020262774172204 0.0433561379514779 1.0 1.0 52 P18077,Q96L73,P62857,P39019,Q9Y3A5,P08708,P11766,P42771,O60934,P62081,O60832,Q13492,Q07812,P61353,P62847,P62899,P60866,P46100,P54132,P61011,P61313,P62244 22 +Red green dyschromatopsia 0.9427531393042357 1.9895557018701415 0.0466399000483432 1.0 1.0 3 Q9H6K4 1 +Narrow internal auditory canal 0.8598970930859487 1.9595702824002457 0.0500460376569087 1.0 1.0 4 P31749,O15160 2 +Abnormality of the internal auditory canal 0.8598970930859487 1.9595702824002457 0.0500460376569087 1.0 1.0 4 P31749,O15160 2 +Abnormality of the endometrium 0.7169725285172301 1.9295807667254867 0.0536588038088274 1.0 1.0 8 Q86W42 1 +Abnormal nasal mucosa morphology 0.918570706161946 1.8984802600901711 0.0576328457163808 1.0 1.0 3 P57076 1 +Myocardial fibrosis 0.8444258240777048 1.8981863670507224 0.0576715360527164 1.0 1.0 4 Q9H2U2 1 +Hypoplastic facial bones 0.6499524954633319 1.8932114757821628 0.0583297519016894 1.0 1.0 16 Q15056,O15160,Q8NFV4,O43709,Q7RTS9,Q9H9Y6,P78347 7 +Myelodysplasia 0.4070601041579682 1.8728008054722496 0.0610958967253627 1.0 1.0 51 P18077,P62857,P39019,Q9Y3A5,P08708,P11766,Q06124,P42771,P62081,O60832,P61353,P62847,P62899,P60866,P46100,P54132,P61011,P61313,P62244 19 +Speech articulation difficulties 0.8332803033498126 1.853760390162245 0.0637734476251226 1.0 1.0 4 P42858 1 +Proximal renal tubular acidosis 0.9058849492560034 1.8504309905989995 0.0642514557844342 1.0 1.0 3 Q9BRT2 1 +Absent brainstem auditory responses 0.8280001554392393 1.8326556079131 0.0668538028922587 1.0 1.0 4 Q13724 1 +Productive cough 0.6669705502581338 1.8201045355149992 0.0687430870534191 1.0 1.0 9 P57076 1 +Abnormality of the calcaneus 0.6927742016114055 1.8164190149283788 0.069306120524315 1.0 1.0 8 Q7RTS9,P55084,O75787 3 +Multifocal seizures 0.7674163803341734 1.815494858356204 0.0694478954031037 1.0 1.0 5 Q9UGM6 1 +Abnormal echocardiogram 0.7668181195257068 1.8129602777110532 0.0698379481204845 1.0 1.0 5 Q969Y2 1 +Stuttering 0.8951028609648988 1.809451902442042 0.0703808259970093 1.0 1.0 3 P03915 1 +Rhinitis 0.7391351559997589 1.8048770313030564 0.0710939267572294 1.0 1.0 6 P54132,P57076 2 +Impaired horizontal smooth pursuit 0.8191577439300131 1.7972309924737335 0.0722989562594287 1.0 1.0 4 P41440,P35251 2 +Cerebellar hemorrhage 0.7623442780291373 1.7939895910905717 0.0728148302348814 1.0 1.0 5 P05165,P22033,P26440 3 +Axial dystonia 0.885276923724734 1.7719992035019334 0.0763946894402283 1.0 1.0 3 Q9ULV3 1 +Distal peripheral sensory neuropathy 0.7569076284248208 1.7708966782311293 0.0765778848471367 1.0 1.0 5 P03915,Q5T440,P55084 3 +Positive romberg sign 0.65589236038574 1.7655234400599136 0.0774758343340926 1.0 1.0 9 Q9H6K4,P41440 2 +Perimembranous ventricular septal defect 0.7060985781897937 1.7628474939432346 0.0779262146543215 1.0 1.0 7 Q5SRE5,P46100,Q86W42 3 +Attenuation of retinal blood vessels 0.6530321311782529 1.7513963161070856 0.0798776671221035 1.0 1.0 9 Q96S66,P50213,P38435,P04439,O75643,Q03426 6 +Broad neck 0.6249398554054844 1.7439761010682235 0.081163257249897 1.0 1.0 11 P62857,O60826 2 +Stridor 0.7243046556584015 1.7404733328160678 0.0817759386547494 1.0 1.0 6 Q969Y2 1 +Abnormal thalamic mri signal intensity 0.7009324476349579 1.7394656420133188 0.0819528906500579 1.0 1.0 7 P31749,Q12824,Q969Y2 3 +Carpal bone hypoplasia 0.720045477812633 1.7219144836210296 0.085085010872973 1.0 1.0 6 Q7RTS9 1 +Hydrocele testis 0.7196740873824208 1.7202949058971333 0.0853788489645248 1.0 1.0 6 P31749,Q96L73 2 +Abnormal greater sciatic notch morphology 0.6952083724864393 1.7135098981587296 0.0866187739574897 1.0 1.0 7 Q7RTS9 1 +Abnormal hand bone ossification 0.6914794391428025 1.6965743205348771 0.0897771681618158 1.0 1.0 7 O43909 1 +Restrictive cardiomyopathy 0.8655006031363153 1.6963269162334986 0.0898239858061695 1.0 1.0 3 Q969N2,Q7L590 2 +Impaired visuospatial constructive cognition 0.6911479273519283 1.6950677008821569 0.0900625785646269 1.0 1.0 7 P42858 1 +Abnormal right atrium morphology 0.8625264800058008 1.684914822774221 0.0920050063168642 1.0 1.0 3 Q7L590 1 +Epiphyseal dysplasia 0.6885306100943552 1.6831671222884197 0.0923427435164954 1.0 1.0 7 Q7RTS9 1 +Flared nostrils 0.734651368629396 1.6759281754243396 0.0937522620856514 1.0 1.0 5 P08559,P60953 2 +Aplasia hypoplasia involving the carpal bones 0.6862597342885909 1.6728336977982985 0.0943600390607692 1.0 1.0 7 Q7RTS9 1 +Progressive cerebellar ataxia 0.4620704280799731 1.6701784945188232 0.0948840535604591 1.0 1.0 42 P19404,Q13148,Q9BSH4,Q96CU9,P08559,O15020,P28331,P42858,Q8NI60,Q03426,P41440,Q9P0J0,P35251 13 +Glossoptosis 0.6824967175648284 1.655694232127402 0.0977837559640399 1.0 1.0 7 O15160 1 +Dyschromatopsia 0.6808751436209195 1.6483023149665217 0.0992906499414143 1.0 1.0 7 Q9H6K4 1 +Abnormality of body mass index 0.852582776667248 1.6467031039454398 0.0996190859157963 1.0 1.0 3 P42858 1 +Limited extraocular movements 0.6543457163217966 1.6346545026369623 0.1021214952263736 1.0 1.0 8 Q99653,O43819,P11047 3 +Deviation of the 2nd finger 0.8491429625458042 1.633465132513026 0.1023712081969177 1.0 1.0 3 Q9H6K4 1 +Decreased activity of mitochondrial complex i 0.4840819081379838 1.6181840411565267 0.105622941074424 1.0 1.0 39 P19404,O43676,Q86Y39,Q8IUX1,Q969Y2,Q96EY7,O75380,P28331,Q9NPL8,Q96CU9,Q5T440 11 +Type 2 muscle fiber atrophy 0.774221041495584 1.6157550888737404 0.106147275155872 1.0 1.0 4 P11047,Q8TCS8 2 +U shaped upper lip vermilion 0.8438161034794909 1.6129462117341615 0.1067561941548747 1.0 1.0 3 P46100 1 +Horseshoe kidney 0.4452088713810198 1.6109419840480832 0.1071923680906552 1.0 1.0 43 O43909,Q12824,P60866,P18077,P62244,P61353,P62857,P62081,P62847,P62899,P61313,O60832,Q86W42 13 +Abnormal protein o linked glycosylation 0.7729617248232264 1.6106378136295598 0.1072586869781571 1.0 1.0 4 Q8N511 1 +Abnormality of the ankles 0.401170954390757 1.602372159942758 0.1090733373750989 1.0 1.0 47 Q969N2,O60762,Q15056,Q8TCS8,O95140,Q9NP72,O60220,Q8NFV4,Q96L73,P42858,O43709,Q5JTV8,Q7RTS9,O75787 14 +Abnormality of carpal bone ossification 0.6923511164905612 1.600607722713733 0.1094638307105235 1.0 1.0 6 O43909 1 +Abnormal circulating branched chain amino acid concentration 0.7165443367243582 1.5981930387227683 0.1100000225153503 1.0 1.0 5 Q96RQ3,P09622,O15382 3 +Paronychia 0.7694705058020056 1.596443137596571 0.1103898915499177 1.0 1.0 4 P54132 1 +Premature ovarian insufficiency 0.5871565733312369 1.5878565352180014 0.1123187839217436 1.0 1.0 20 P54132,Q9UI10,O75616,O60934,Q86W42 5 +Triangular mouth 0.6668917521451766 1.5844140782907616 0.1130995202684679 1.0 1.0 7 P11047 1 +Aplasia hypoplasia of the thyroid gland 0.7130356065178001 1.5830854589551049 0.1134019874201264 1.0 1.0 5 Q15738,O14654,Q9H9Y6,O15160 4 +Myofibrillar myopathy 0.7121832445775627 1.5794133962436911 0.1142412666333898 1.0 1.0 5 P31749 1 +Capillary hemangioma 0.5933548366428079 1.577912214360795 0.1145857785427417 1.0 1.0 11 O43909 1 +Gaze evoked nystagmus 0.5932653119764928 1.5747695530883594 0.1153096466666352 1.0 1.0 12 O15020 1 +Abnormality of the periungual region 0.7070663212848292 1.557352911802986 0.1193867193806816 1.0 1.0 5 P54132 1 +Male infertility 0.6368501686505196 1.551197570140225 0.1208543442925698 1.0 1.0 8 P51809,P54132,P57076 3 +Aplasia hypoplasia of the spleen 0.703874673961816 1.5435791470300646 0.1226903199997515 1.0 1.0 5 P57076 1 +Abnormal proportion of cd8 positive t cells 0.6773237831579793 1.5343711328347218 0.1249383751261876 1.0 1.0 6 O43909,P54132 2 +Decreased fertility in females 0.6537590610913627 1.524195763999313 0.1274598158896074 1.0 1.0 7 P54132 1 +Poor fine motor coordination 0.6534682115341248 1.5228599614475138 0.1277937446653436 1.0 1.0 7 P42858 1 +Paroxysmal bursts of laughter 0.8201467079585708 1.5215242843845944 0.1281283219577085 1.0 1.0 3 P46100 1 +First degree atrioventricular block 0.8197165523962471 1.519859487138315 0.1285462944047599 1.0 1.0 3 Q9HD47 1 +Abnormal circulating amino acid concentration 0.3796997673973682 1.5158969668854203 0.129545407393143 1.0 1.0 54 Q96EY8,Q9HCC0,P11498,Q15046,P30038,P41440,P09001,Q99797,Q8IUX1,P08559,P20674,P09622,Q4G0N4,P78330,Q9Y617,P03915,O75880,P05165,P22033,O15382,Q96RQ3,Q7LG56,Q9P0J0 23 +3 methylglutaconic aciduria 0.605597699746889 1.5153234412340328 0.1296905147968092 1.0 1.0 9 P31040,Q9H6K4,Q9H078,Q53H12 4 +Abnormal mitochondria in muscle tissue 0.5587598457144469 1.5143549203816389 0.1299358461697572 1.0 1.0 25 P03915,O43676,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9 8 +Spinal canal stenosis 0.6048648915989291 1.511654611983417 0.1306217507998148 1.0 1.0 9 O43909 1 +Dysmetric saccades 0.6500357883771478 1.5070891323828546 0.1317878120329187 1.0 1.0 7 O15020,O95140 2 +Central scotoma 0.5789877093863608 1.5069952330473804 0.131811879087774 1.0 1.0 10 P03915,Q9H6K4,O95140,O60220 4 +Abnormal csf metabolite level 0.3926432119902882 1.5063814176607495 0.1319692881678325 1.0 1.0 61 Q5T160,Q8TCS8,O43676,P03915,Q9BSH4,Q86Y39,O43819,Q96CU9,Q8IUX1,O75380,P08559,P28331,Q9NPL8,Q8NI60,P30038,Q9P0J0 16 +Lactic acidosis 0.4505862464625894 1.5044478740486231 0.1324660853623398 1.0 1.0 92 O43676,Q00325,Q3LXA3,Q969Y2,P11498,Q9Y3D3,P40939,Q9NPL8,Q8NI60,Q9UGM6,P10515,P19404,Q99797,Q02218,Q8IUX1,P08559,P28331,Q96CU9,Q5T440,Q9UMS0,P09622,Q15031,Q86Y39,Q4G0N4,O75380,Q9H845,Q9Y2R9,P08574,P03915,P55084,P05165,Q5JTZ9,O43819,Q6P4A7,Q7LG56,Q9P2R7 36 +Long nose 0.6264543981992751 1.5014418397810387 0.1332413190139276 1.0 1.0 8 O43909,Q96S52,Q86W42 3 +Abnormal natural killer cell morphology 0.6928328795570398 1.4958521345637374 0.1346921919862687 1.0 1.0 5 Q7L590 1 +Reduced natural killer cell count 0.6928328795570398 1.4958521345637374 0.1346921919862687 1.0 1.0 5 Q7L590 1 +Short face 0.8117258830525544 1.488915257389493 0.1365096853121237 1.0 1.0 3 O15160 1 +Abnormality of the vertebral endplates 0.64213604711076 1.470749346233511 0.1413589157112196 1.0 1.0 7 Q7RTS9 1 +Decreased number of large peripheral myelinated nerve fibers 0.6412610615271368 1.4667208478143157 0.1424520092037287 1.0 1.0 7 Q8TB36,Q7LG56,Q9NZJ4 3 +Axonal degeneration regeneration 0.6850123683537508 1.461984520222782 0.1437454518620964 1.0 1.0 5 O60333,Q8TB36,O95140 3 +Focal t2 hyperintense brainstem lesion 0.5625730009251702 1.459632895530896 0.1443909934235412 1.0 1.0 21 O43676,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9 7 +Abnormal basal ganglia mri signal intensity 0.5207647506414809 1.458405702758322 0.1447287497141727 1.0 1.0 31 O75340,Q9NYY8,P19404,P03915,Q9BSH4,Q96CU9,Q969Y2,P08559,P28331,Q8NI60,Q9P0J0 11 +Abnormal sella turcica morphology 0.5939235708917698 1.4568212911322211 0.1451657171240303 1.0 1.0 9 Q7RTS9 1 +Abnormal brainstem mri signal intensity 0.5518444574614829 1.4493688789398067 0.1472345948948328 1.0 1.0 24 O43676,Q86Y39,Q8IUX1,Q969Y2,O75380,P28331,Q9NPL8,Q96CU9 8 +Right ventricular hypertrophy 0.6818139746665913 1.448119824814061 0.1475835420401641 1.0 1.0 5 Q969Y2 1 +Long upper lip 0.731665804489557 1.4420848554796677 0.1492784368594866 1.0 1.0 4 Q9BZK7 1 +Abnormal subcutaneous fat tissue distribution 0.679511842490544 1.438135794610603 0.1503955281745292 1.0 1.0 5 P31749 1 +Color vision defect 0.5676384189301469 1.4380880020687534 0.1504090864260521 1.0 1.0 12 Q9H6K4,O95140,Q99798 3 +Slowly progressive 0.3798491397439037 1.433895468133037 0.1516020953252912 1.0 1.0 58 P31483,O75340,Q99720,Q9Y281,O95140,Q15120,O60333,Q9NXN4,Q04446,Q9P0J0,O15020,Q5JTV8,P41440,Q5T440,O75787 15 +Psychotic mentation 0.6784927852231842 1.4337151243462354 0.1516535743681979 1.0 1.0 5 P03915 1 +Choroid plexus carcinoma 0.7285464101105099 1.4293046664911682 0.152916685353041 1.0 1.0 4 Q12824 1 +Thin nail 0.7942487709267437 1.4211301064574198 0.1552789390415605 1.0 1.0 3 Q96L73 1 +Quadriceps muscle weakness 0.6748586922845325 1.4179449238250033 0.1562068452004537 1.0 1.0 5 O95140 1 +Total anomalous pulmonary venous return 0.7928276096388901 1.4156130665374569 0.1568888235167969 1.0 1.0 3 P60953 1 +Renal tubular dysfunction 0.4410850772400077 1.4118855369798329 0.1579836669598386 1.0 1.0 41 P19404,P03915,O43676,Q86Y39,O43819,Q9BRT2,Q8IUX1,P11498,O75380,P28331,Q9NPL8,Q96CU9 12 +Abnormal epiphysis morphology of the phalanges of the hand 0.5842515437881018 1.4082791192190085 0.1590484361646804 1.0 1.0 9 Q7RTS9,Q9H9E3 2 +Cone shaped epiphyses of the phalanges of the hand 0.5842515437881018 1.4082791192190085 0.1590484361646804 1.0 1.0 9 Q7RTS9,Q9H9E3 2 +Decreased circulating total igm 0.5597577566839088 1.4000560036152576 0.161496548566224 1.0 1.0 11 Q969N2,O43909,P54132 3 +Proximal tubulopathy 0.5268727486800895 1.3953245315627127 0.1629179976957755 1.0 1.0 28 P19404,P03915,O43676,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9 9 +Abnormality of the costochondral junction 0.7197316451441311 1.3931647515310193 0.1635699760933922 1.0 1.0 4 Q7RTS9,Q9Y3A5 2 +Enlargement of the costochondral junction 0.7197316451441311 1.3931647515310193 0.1635699760933922 1.0 1.0 4 Q7RTS9,Q9Y3A5 2 +Vitiligo 0.6250412562111658 1.3919382659880797 0.1639410929277094 1.0 1.0 7 P03915 1 +Pulmonary cyst 0.6448724773799774 1.3905568026845108 0.1643598631827092 1.0 1.0 6 P31749 1 +Retinal pigment epithelial atrophy 0.7185559098535446 1.3883417827251447 0.1650329947892082 1.0 1.0 4 Q8TC12,P50213 2 +Molluscum contagiosum 0.783458433466909 1.3792276048108607 0.1678245894292023 1.0 1.0 3 O95394 1 +Unusual skin infection 0.783458433466909 1.3792276048108607 0.1678245894292023 1.0 1.0 3 O95394 1 +Paroxysmal involuntary eye movements 0.5455665197237801 1.3749730347064753 0.1691398047601295 1.0 1.0 22 O43676,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9 7 +Abnormality of the musculature of the hand 0.453537046611519 1.374805019579983 0.1691919015193581 1.0 1.0 39 P60866,P11047,O95140,P18077,Q15120,P61353,Q96IJ6,P62857,P62081,O60568,P39019,P62847,P62899,P61313,P62244,P31483 16 +Emg impaired neuromuscular transmission 0.6410318033249025 1.373482329106979 0.1696024510051037 1.0 1.0 6 P11047 1 +Abnormal proportion of cd4 positive t cells 0.5980570190774411 1.365077826364872 0.172228590406918 1.0 1.0 8 O43909,P54132,O75787 3 +Lower eyelid coloboma 0.7128205128205136 1.3648075475800951 0.1723135459709017 1.0 1.0 4 Q15427,Q9H9Y6,O15160 3 +Blepharophimosis 0.3631870814445202 1.361954793927443 0.1732121521121903 1.0 1.0 53 Q9NXH9,O75175,Q15056,Q9NP72,P51608,Q8NFV4,Q9BZK7,P42858,O43709,Q13724,P78347,Q9BPU6,Q86W42 13 +Abnormal central sensory function 0.7118267798428014 1.360728853653561 0.173599392756325 1.0 1.0 4 P31749,Q12824 2 +Blue irides 0.5511079205199505 1.3602978603801614 0.1737356851920144 1.0 1.0 10 Q8NFV4,Q05086,Q15056,O43709 4 +Abnormal cell proliferation 0.711582603513121 1.3597266086964328 0.1739164545420615 1.0 1.0 4 O43909 1 +Absent forearm bone 0.6174516908212602 1.3568910161280516 0.1748158418195327 1.0 1.0 7 O75369,O94761,Q15427,Q9BXW9,Q9Y5S9,O75962 6 +Germ cell neoplasia 0.5512412980247893 1.3548856116678285 0.1754540045237789 1.0 1.0 11 P31749,Q96L73,P42771 3 +Abnormal csf pyruvate family amino acid concentration 0.709987723458463 1.353179869109539 0.1759981748134382 1.0 1.0 4 P08559 1 +Medial flaring of the eyebrow 0.7098767536358033 1.3527243298208649 0.1761437148086098 1.0 1.0 4 Q96ST3 1 +Abscess 0.5487484980318597 1.3478720011616272 0.1776995548399282 1.0 1.0 10 P42771,O95394,P54132 3 +Cystoid macular edema 0.7082924756884703 1.346220418639588 0.1782314419169861 1.0 1.0 4 P04439,P50213 2 +Methylmalonic aciduria 0.6341500161513008 1.3428681249402408 0.179314679343215 1.0 1.0 6 Q4G176,Q9P2R7,P22033 3 +Methylmalonic acidemia 0.6341500161513008 1.3428681249402408 0.179314679343215 1.0 1.0 6 Q4G176,Q9P2R7,P22033 3 +Low hanging columella 0.548459850337645 1.340133080774763 0.1802020828811876 1.0 1.0 11 Q86W42 1 +Microcytic anemia 0.5700074693312374 1.33672105852161 0.1813137053953224 1.0 1.0 9 P46100,P22830,Q3LXA3,Q9UBX3,Q9Y285 5 +Renal agenesis 0.3645900196243431 1.3353524871680174 0.1817610075137872 1.0 1.0 55 Q96C36,P18077,Q9UBM7,Q15058,Q96L73,P62857,P39019,Q86W42,P08708,Q86XL3,Q06124,P46777,P62854,P62081,P60953,P61353,P62847,P62899,P60866,P46100,Q15427,O43819,P61313,Q15738,P62244 25 +Coarctation of aorta 0.4556151811983339 1.3291288488088804 0.1838054640058606 1.0 1.0 38 P08708,P62140,P60866,P18077,Q06124,Q14839,Q9UBM7,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 15 +Lower limb hypertonia 0.5447527740978926 1.326829463172503 0.1845651018112319 1.0 1.0 10 P46100,Q8TCS8 2 +Abnormal hemoglobin 0.5202237089969554 1.3248435765663926 0.185223038217424 1.0 1.0 27 P08708,P60866,P46100,P18077,P62244,P61353,P62857,P62081,P62847,P39019,P62899,P61011,P61313,Q9Y3A5,Q9UKG1 15 +Abnormality of the odontoid process 0.5642344632584507 1.3077117658142834 0.1909710910831432 1.0 1.0 9 Q7RTS9 1 +Shield chest 0.6255660617175793 1.3046538661042648 0.1920107372791681 1.0 1.0 6 Q7RTS9,Q06124,Q99575 3 +Radial deviation of the hand or of fingers of the hand 0.5428808155082975 1.302749308487596 0.1926603620217752 1.0 1.0 13 Q15427,P08069,P46100,Q96ST3 4 +Limited elbow extension 0.54247331820876 1.3005557810236876 0.1934105511562442 1.0 1.0 13 Q7RTS9,Q9H6K4 2 +Bilateral external ear deformity 0.6958920890682752 1.2952981286283558 0.1952174045217762 1.0 1.0 4 P14923,P15924 2 +Metaphyseal sclerosis 0.603062034417324 1.2903870666571573 0.1969163003662704 1.0 1.0 7 Q14807,O94761,Q5F1R6,P61011,Q9Y3A5 5 +Mild microcephaly 0.6214934037033153 1.2865156085896774 0.1982631750137695 1.0 1.0 6 Q86W42 1 +Scotoma 0.5390100273481602 1.2819175374421816 0.1998715752064774 1.0 1.0 13 O95140,Q9H6K4,O60220,Q99798,P03915 5 +Abnormal circulating ceruloplasmin concentration 0.756332931242493 1.2738291662743997 0.2027239662148805 1.0 1.0 3 Q10567,Q8N511 2 +Lethargy 0.4092568902879973 1.273100384934256 0.2029824223878262 1.0 1.0 82 O43676,P18077,Q9UI10,P62857,Q9Y3D3,P40939,Q9NPL8,P19404,P26440,Q8IUX1,P62081,P08559,P28331,Q96CU9,Q96IX5,Q9UMS0,P20674,Q86Y39,P61353,O75380,P62847,P62899,P55084,P60866,P05165,P22033,P23786,Q96RQ3,Q7LG56,P61313,P62244 31 +Persistence of hemoglobin f 0.5274974732442315 1.2684063553202325 0.2046528732281767 1.0 1.0 22 P08708,P60866,P18077,P62244,P61353,P62857,P62081,P62847,P39019,P62899,P61011,P61313,Q9Y3A5 13 +Uveitis 0.5335059391086557 1.2676256112032114 0.2049316813631505 1.0 1.0 10 P14174 1 +Elfin facies 0.5766946199809655 1.2622941420885068 0.2068429637907742 1.0 1.0 8 Q8NFV4,P78347,Q15056,O43709 4 +Right ventricular cardiomyopathy 0.6874811463046768 1.260753948831292 0.2073975101597918 1.0 1.0 4 P15924,P14923,Q14126 3 +Hypercalcemia 0.5224495961123008 1.2538714693354365 0.2098887266672555 1.0 1.0 23 Q969N2,Q15056,O60333,P53680,Q8NFV4,Q96L73,O43709,O75962,P78347 9 +Branchial fistula 0.6368738526231361 1.252778694217792 0.2102862575067228 1.0 1.0 5 O15160 1 +Abnormality of the columella 0.5314949295558605 1.2448349896877176 0.213192411589892 1.0 1.0 17 Q13868,Q86W42 2 +Multiple lipomas 0.5728145757612171 1.2436297302505075 0.2136358689801594 1.0 1.0 8 P31749,P03915,O95140 3 +Type ii transferrin isoform profile 0.7484206509776032 1.2430981010664726 0.2138316854738957 1.0 1.0 3 O75787 1 +Muscular ventricular septal defect 0.748407190044696 1.2430458335648251 0.213850944300566 1.0 1.0 3 Q86W42 1 +Malignant genitourinary tract tumor 0.5225485934450868 1.239301184962657 0.2152339800540621 1.0 1.0 22 P08708,P60866,P54132,P18077,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 12 +Mixed demyelinating and axonal polyneuropathy 0.682138162599983 1.2388137292608128 0.2154144882854409 1.0 1.0 4 P03915 1 +Polyphagia 0.608426187449671 1.228306560886659 0.2193319090060299 1.0 1.0 6 P42858 1 +Abnormal metaphyseal trabeculation 0.6081990607978939 1.2272948429441597 0.219711793212034 1.0 1.0 6 Q9BUR4,O60832,Q01970 3 +Thenar muscle atrophy 0.7429256110781332 1.2217665572679386 0.2217959186828708 1.0 1.0 3 O60568 1 +Broad face 0.6778193211484189 1.22108346200373 0.2220544206900816 1.0 1.0 4 Q9BZK7,Q6PJG6 2 +Nonketotic hypoglycemia 0.6777182457266824 1.2206685759807645 0.2222115302448468 1.0 1.0 4 P23786,Q9H845 2 +Neoplasm of fatty tissue 0.5258185691290591 1.2201713385843902 0.2223999295713072 1.0 1.0 11 P31749,P03915,O95140 3 +Fluctuations in consciousness 0.5878240845434559 1.219949908134559 0.2224838646166467 1.0 1.0 7 P03915 1 +Abnormality of vitamin b metabolism 0.5278284666516921 1.2198403280457346 0.2225254102442972 1.0 1.0 14 P10515,P22033,Q4G176,P41440,P30038 5 +Abnormal ovarian physiology 0.516105859705118 1.2161405912861705 0.2239313700626017 1.0 1.0 23 P54132,Q9UI10,O75616,O60934,Q86W42 5 +Impaired smooth pursuit 0.5240308872778648 1.21519010343267 0.2242935941077903 1.0 1.0 19 Q9UGM6,O15020 2 +Neck flexor weakness 0.6280809442061659 1.2145238239875948 0.2245477579493962 1.0 1.0 5 Q99720,Q9Y281 2 +Aortic arch aneurysm 0.5663268184308974 1.2124349281851514 0.2253459374548492 1.0 1.0 8 Q8NFV4,Q15056,O43709 3 +Unsteady gait 0.3469221264602644 1.2114990031567563 0.2257042164779368 1.0 1.0 52 Q9UI10,Q9H6K4,Q9ULV3 3 +Parakeratosis 0.6262563132505163 1.2065878119440152 0.2275909228577108 1.0 1.0 5 Q15738,Q03426,P15924 3 +Abnormality of the thenar eminence 0.5222704902496484 1.2052083735170998 0.2281228706430427 1.0 1.0 19 P08708,P60866,P18077,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 11 +Hypoplasia of the odontoid process 0.564560295122901 1.2039449660266284 0.2286108503924806 1.0 1.0 8 Q7RTS9 1 +Cerebral hemorrhage 0.5231908024604028 1.2007792720671944 0.2298368343998165 1.0 1.0 12 Q8NBJ5,P36957,Q12824,O60333,P31749 5 +Abnormal right ventricle morphology 0.5427631431887441 1.199913389835232 0.2301729791638527 1.0 1.0 9 Q969Y2 1 +Acute myeloid leukemia 0.4456556590526978 1.197377772791191 0.2311593431549812 1.0 1.0 37 P08708,P60866,O60832,P54132,P11766,P18077,P62244,P42771,Q13492,P61353,P62857,P62081,P62847,P39019,P62899,P61011,P61313,Q9Y3A5 18 +Abnormality of the carpal bones 0.5206216587809231 1.1958650354338995 0.2317492315772282 1.0 1.0 19 Q7RTS9,O43909,Q9Y2D4,Q15125 4 +Chromosome breakage 0.5219592801789041 1.1942251692511534 0.2323899001132034 1.0 1.0 12 P31749,P54132 2 +Intestinal pseudo obstruction 0.5191060557280441 1.1919533805503912 0.2332795255383977 1.0 1.0 10 P03915,P42771 2 +Hemianopia 0.561831726257759 1.190835467360882 0.2337181823404122 1.0 1.0 8 P31749,P03915 2 +Emg decremental response of compound muscle action potential to repetitive nerve stimulation 0.6701488558697842 1.189608769077206 0.2342001976349856 1.0 1.0 4 P11047 1 +Response to drugs acting on neuromuscular transmission 0.6701488558697842 1.189608769077206 0.2342001976349856 1.0 1.0 4 P11047 1 +Abnormal mitochondrial shape 0.6222174028775461 1.1890252823133605 0.2344297182673502 1.0 1.0 5 Q00325 1 +Nasolacrimal duct obstruction 0.622194027358886 1.1889236570092685 0.2344697099325716 1.0 1.0 5 P62140,P48651 2 +Abnormality of circulating fibrinogen 0.5183907577469613 1.1882003786566322 0.2347544745587617 1.0 1.0 10 Q9BZK7 1 +Ketoacidosis 0.5180395630465283 1.186357994124564 0.2354809529398958 1.0 1.0 10 P55809,P22033,P26440,Q4G176,Q9HCC0,P08574 6 +Impaired social interactions 0.3461583409637652 1.183325620171081 0.2366801228116366 1.0 1.0 53 O43909,P19404,O43676,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9,Q9P0J0 10 +Abnormal posterior segment imaging 0.6207994763060227 1.1828612784614565 0.2368641299073233 1.0 1.0 5 Q96S66,P04439,P50213 3 +Hypoventilation 0.520080375395696 1.177953710927711 0.2388150605741072 1.0 1.0 14 Q9Y281,P11047,O43819,O75380,Q13724 5 +Reticulocytopenia 0.5115702119981663 1.1749244436941608 0.2400249453106693 1.0 1.0 22 P08708,P60866,P18077,P62244,P61353,P62857,P62081,P62847,P39019,P62899,P61313,Q9Y3A5 12 +Muscle abnormality related to mitochondrial dysfunction 0.3951155768381305 1.1704922677741003 0.2418029240021977 1.0 1.0 43 P19404,Q8TCS8,O43676,P03915,Q9BSH4,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9 11 +Overfriendliness 0.5765093062629181 1.1676938516703408 0.242930277733659 1.0 1.0 7 Q8NFV4,Q15056,O43709 3 +Flat cornea 0.5765093062629181 1.1676938516703408 0.242930277733659 1.0 1.0 7 Q8NFV4,Q15056,O43709 3 +Phonophobia 0.5765093062629181 1.1676938516703408 0.242930277733659 1.0 1.0 7 Q8NFV4,Q15056,O43709 3 +Nystagmus induced head nodding 0.5765093062629181 1.1676938516703408 0.242930277733659 1.0 1.0 7 Q8NFV4,Q15056,O43709 3 +Abnormality of the wrist 0.4481844484514096 1.1658849618390217 0.2436609598618266 1.0 1.0 36 O43909,P11047,Q9H6K4,Q9Y2D4,P31749,Q7RTS9,Q15125 7 +Poor eye contact 0.375893160706043 1.160186606725678 0.2459728387450945 1.0 1.0 45 P19404,O43676,Q86Y39,Q96RP9,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9,Q9P0J0 10 +Pure red cell aplasia 0.5110606889340374 1.1598521702091225 0.2461089990948635 1.0 1.0 21 P08708,P60866,P18077,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 11 +Lower limb metaphyseal irregularity 0.6619332683237769 1.155927901728712 0.2477106487903113 1.0 1.0 4 P26373,Q9Y3A5 2 +Wide nasal ridge 0.6141031449936806 1.1537651862996228 0.2485964506549369 1.0 1.0 5 Q9BZK7 1 +Recurrent gastroenteritis 0.6138880856043445 1.1528311784344958 0.2489796844254006 1.0 1.0 5 P54132 1 +High hypermetropia 0.5114692495267951 1.15192341384209 0.2493525459219683 1.0 1.0 10 Q8NFV4,Q15056,O43709 3 +Decreased pulmonary function 0.6608558485033196 1.151513854651259 0.2495208987898005 1.0 1.0 4 P31749 1 +Progressive encephalopathy 0.7233035055779136 1.145715104167751 0.2519130521409474 1.0 1.0 3 Q9P2R7 1 +Abnormal circulating ferritin concentration 0.5716206764521417 1.1451409050574295 0.252150793228248 1.0 1.0 7 P41440 1 +Absent thumb 0.4869782078823748 1.1405860720838947 0.2540422159268098 1.0 1.0 28 P08708,P60866,P18077,Q15427,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 12 +Hand tremor 0.5107650227075453 1.134765043136313 0.2564737765109381 1.0 1.0 12 Q9ULM3,O95140,Q15120,Q96KR1,O00567 5 +Adenocarcinoma of the colon 0.5043685645784916 1.1328716995847958 0.2572681361148328 1.0 1.0 22 P08708,P60866,P18077,P61353,P62854,P28340,P62857,P62081,P62847,P39019,P62899,P61313,P62244 13 +Abnormal t cell subset distribution 0.5103726094885158 1.132684981113224 0.2573465669571124 1.0 1.0 12 O43909,O95394,P54132,O75787 4 +Abnormality of urine calcium concentration 0.5113993888252586 1.1311561747371237 0.2579893640690764 1.0 1.0 14 Q969N2,Q15056,P53680,Q8NFV4,O43709 5 +Cellular immunodeficiency 0.5064185479962579 1.1255026229374592 0.2603761063642289 1.0 1.0 10 P31749,Q9BUR4,O60832 3 +Bowel diverticulosis 0.5077714048000425 1.1249492687371612 0.2606105324266936 1.0 1.0 11 P31749,Q8NFV4,Q15056,O43709 4 +Broad foot 0.5071616833909661 1.121742327753465 0.261972013847028 1.0 1.0 11 Q7RTS9,Q9BZK7 2 +Erythroid hypoplasia 0.5060953840535616 1.1215418598640854 0.2620572838080539 1.0 1.0 20 P08708,P60866,P18077,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 11 +Embryonal renal neoplasm 0.5085115388911218 1.118410175543498 0.2633918504049006 1.0 1.0 13 Q96L73,P54132 2 +Pelvic kidney 0.5047260338134554 1.1166599320253168 0.2641397558737073 1.0 1.0 10 Q8NFV4,Q15056,O43709 3 +Narrow forehead 0.331542210087917 1.1118565511003846 0.26619983253118 1.0 1.0 49 Q969N2,Q5T160,P62140,P46100,Q8TD30,P60953,O75787 7 +Partial duplication of the phalanx of hand 0.5016717447973148 1.105769846299053 0.2688261495679827 1.0 1.0 21 P08708,P60866,P18077,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 11 +Recurrent ear infections 0.712907980777465 1.1055355457794105 0.2689276009074182 1.0 1.0 3 P39656 1 +Lacrimal duct stenosis 0.7126055488540528 1.1043681092760655 0.2694334887503986 1.0 1.0 3 P62140,P48651 2 +Severe combined immunodeficiency 0.562348040227525 1.102422361618538 0.2702780943233458 1.0 1.0 7 O43909 1 +Extrapyramidal muscular rigidity 0.560762647998793 1.0951279232033322 0.273460597014399 1.0 1.0 7 Q9H6K4 1 +Barrett esophagus 0.7095669651113438 1.0926438525368332 0.2745502008127329 1.0 1.0 3 Q8N9N2 1 +Vocal cord paresis 0.6461157807335367 1.0912170439441913 0.2751773899111622 1.0 1.0 4 Q8TB36,O95140 2 +Small face 0.3590498220185893 1.0908734993635771 0.2753285494220243 1.0 1.0 46 Q9NXH9,Q9Y281,O75175,P54132,O15160,Q8NFV4,Q96L73,Q96ST3,P42858,O43709,Q9H9Y6 11 +Cytochrome c oxidase negative muscle fibers 0.5194421153434133 1.083340953464891 0.2786571138279894 1.0 1.0 9 Q9BSH4 1 +Cerebellar vermis atrophy 0.5005845585512185 1.08091682068154 0.2797341156290029 1.0 1.0 12 Q99653,Q8WVX9,Q96S52,P42858 4 +Paroxysmal ventricular tachycardia 0.6426363018904527 1.0770135553048197 0.2814742099026515 1.0 1.0 4 Q99996,Q9HD47 2 +Ovarian cyst 0.5005380997873207 1.0713891552553472 0.2839944870104884 1.0 1.0 15 P31749,Q8NFV4,Q15056,O43709 4 +Narrow nasal bridge 0.6410256410256422 1.0704432972484683 0.2844198191338001 1.0 1.0 4 Q9H9E3,Q15233,Q6ZRS2 3 +Decreased circulating gonadotropin concentration 0.6401884312024377 1.0670293244296722 0.2859585942610136 1.0 1.0 4 P31749 1 +Abnormality of chromosome stability 0.4996214317386638 1.06659856398785 0.2861531492355951 1.0 1.0 16 P31749,Q12824,P54132 3 +Abnormality of ocular smooth pursuit 0.487184108684113 1.0601590589753829 0.2890722432546648 1.0 1.0 24 Q9UGM6,O15020 2 +Ventricular preexcitation 0.5344179942830741 1.059567206435011 0.2893415392787357 1.0 1.0 8 Q969Y2 1 +Renal duplication 0.5146135685258191 1.059322347084935 0.2894530009743219 1.0 1.0 9 Q8NFV4,Q15056,O43709 3 +Genu varum 0.49487191630332 1.0572907152187805 0.2903789293977179 1.0 1.0 11 Q7RTS9,Q9Y281 2 +Heat intolerance 0.5899506356332215 1.049127318577512 0.2941195243296641 1.0 1.0 5 Q9H488 1 +Hamartoma of the eye 0.4913746956071726 1.0471388044179677 0.2950355644760392 1.0 1.0 10 O60333,P36957,P31040,P31749 4 +Infertility 0.4935578190073942 1.0439112258632912 0.2965264639203728 1.0 1.0 12 P54132 1 +Abnormality of hair growth 0.5464296916971852 1.0293423424754446 0.3033188326862808 1.0 1.0 7 P78536 1 +Recurrent infection of the gastrointestinal tract 0.5084042075262156 1.0285146916490162 0.303707783565307 1.0 1.0 9 O60934,P54132,P78536 3 +Proximal femoral metaphyseal abnormality 0.6294153374637586 1.023179819669913 0.3062228326031855 1.0 1.0 4 P61011,Q9Y3A5 2 +Increased sensitivity to ionizing radiation 0.6289723411225163 1.0213802082051704 0.3070743385701338 1.0 1.0 4 P31749 1 +Macrocytic anemia 0.4217181744702808 1.0199306944034332 0.3077613310500582 1.0 1.0 37 P08708,P60866,P18077,P62244,Q6P4A7,P61353,P62857,P62081,P62847,P39019,P62899,P61011,P61313,P41440,Q9Y3A5 15 +Rhabdomyosarcoma 0.5065648183938828 1.0194075664590383 0.3080095154826883 1.0 1.0 9 O60934 1 +Axonal loss 0.5256990987216731 1.0180718537192393 0.3086438101792828 1.0 1.0 8 Q8N9N2,P41440,P35251 3 +Neoplasm of the large intestine 0.3320907842402922 1.0156952381084727 0.309774536339253 1.0 1.0 48 P60866,P54132,P18077,P42771,Q07812,P61353,P31749,P62857,P62081,P62847,P62899,P61313,P62244 13 +Zonular cataract 0.4859721180845066 1.0041408608014304 0.3153107226807969 1.0 1.0 12 Q03426,Q9H6K4,Q99797 3 +Freckling 0.4846064833930372 1.0037887102477256 0.3154804672538431 1.0 1.0 11 P62140,O60934,Q9H488 3 +Easy fatigability 0.4797722371458198 1.0025338415472167 0.3160858304487228 1.0 1.0 23 P11047,Q969Y2 2 +Abnormality of corneal thickness 0.4871559131150809 1.0003281753348805 0.3171517162758301 1.0 1.0 17 O75695,Q15555,Q6P2Q9,Q13099,P50213,Q92620,O94906,Q10567,O75643,O43837 10 +Single naris 0.6846990008257077 0.9971214396339032 0.3187055675308439 1.0 1.0 3 A6NHR9 1 +Aplasia hypoplasia of metatarsal bones 0.5209883981203158 0.9957236890234544 0.3193844168587958 1.0 1.0 8 Q7RTS9,Q96S52 2 +Abnormal circulating carbohydrate concentration 0.3826857716426306 0.995608080228483 0.3194406072296361 1.0 1.0 42 O43676,Q86Y39,Q8IUX1,Q96C23,P11498,O75380,P08559,P28331,Q9NPL8,Q96CU9 10 +Cerebellar dysplasia 0.5774859355243482 0.9954158478477524 0.319534053962182 1.0 1.0 5 P60953 1 +Macrovesicular hepatic steatosis 0.5388146141456697 0.9945353365623943 0.3199623108314218 1.0 1.0 7 P23786,Q7LG56,Q96AX1 3 +Decreased absent ankle reflexes 0.4848065358240802 0.9903693454556542 0.3219936230960987 1.0 1.0 18 O95140,Q15120,O95394,Q9H6K4,O75787 5 +Ulnar deviation of the hand 0.6212743210753675 0.9901582791847516 0.3220967612719778 1.0 1.0 4 Q9BPU6 1 +Chorioretinal degeneration 0.5760410380205142 0.98920682442874 0.3225619601483793 1.0 1.0 5 O75695,P04181,P35222,P40939 4 +Increased mean corpuscular volume 0.4751244464826408 0.9891189742279968 0.3226049352160682 1.0 1.0 24 P08708,P60866,P18077,P62244,P61353,P62857,P62081,P62847,P39019,P62899,P61011,P61313,Q9Y3A5 13 +Pollakisuria 0.620925475735489 0.988745792748753 0.3227875319092779 1.0 1.0 4 O60934 1 +Limited elbow movement 0.3968967292360962 0.9881269524146032 0.3230904773463061 1.0 1.0 40 Q7RTS9,O43909,Q9H6K4 3 +Polygenic inheritance 0.5757427294345449 0.9879254207986992 0.3231891745926138 1.0 1.0 5 O60934,Q07812 2 +Renovascular hypertension 0.4987435761044295 0.9807920352323848 0.326695306764468 1.0 1.0 9 Q8NFV4,Q15056,O43709 3 +Metabolic acidosis 0.3394270117528966 0.980669480199844 0.326755758930735 1.0 1.0 60 Q07021,P23786,P22033,P09622,P26440,P05165,Q02218,Q00325,Q96RQ3,O43819,Q9BRT2,Q96RP9,Q16795,P11498,Q9H2U2,Q92947,Q5T440,P14927 18 +Abnormal t cell morphology 0.4830705386281962 0.9771107656536744 0.3285143185679664 1.0 1.0 16 O43909,P54132,O95394,O60934,Q7L590,O75787 6 +Retinal hamartoma 0.4975641371878605 0.974985304432668 0.329567549564578 1.0 1.0 9 O60333,P36957,P31040,P31749 4 +Eeg with focal sharp waves 0.6788299155609175 0.974714167439873 0.3297020633711676 1.0 1.0 3 Q9Y617,P08559 2 +Action tremor 0.3368486367770104 0.9735252789677044 0.3302923027133644 1.0 1.0 59 Q99720,Q9H6K4,P31749,O15020,P03915,P41440 6 +Delayed eruption of permanent teeth 0.5723189045033703 0.9732305966817404 0.3304387073279571 1.0 1.0 5 Q96L73,Q12824 2 +Osteomalacia 0.6165952192843317 0.9712309234206312 0.3314332981212913 1.0 1.0 4 P53680 1 +Branchial anomaly 0.5152645087431246 0.9686460011682896 0.332721843220203 1.0 1.0 8 O15160 1 +Decreased patellar reflex 0.6771874726890957 0.9684547063781984 0.3328173291968399 1.0 1.0 3 P55084 1 +Leukopenia 0.3212297366101711 0.9672255415253668 0.33343129647076 1.0 1.0 51 P18077,P62857,P39019,Q9Y3A5,P08708,P26440,P11766,P62081,Q9NP81,O60832,O95394,P61353,P62847,P62899,P60866,P22033,Q9BZK7,P61011,P61313,P62244 20 +White hair 0.5707267715615915 0.9664053407291232 0.3338413926766457 1.0 1.0 5 Q9BUR4,O60832 2 +Oral leukoplakia 0.5707267715615915 0.9664053407291232 0.3338413926766457 1.0 1.0 5 Q9BUR4,O60832 2 +Abnormal renal insterstitial morphology 0.4796794124046956 0.9658949605979984 0.3340967442700222 1.0 1.0 13 P23786,Q15056,Q04446,Q8NFV4,O43709,P78347 6 +Abnormal trabecular bone morphology 0.5143124585549126 0.9641510613777045 0.3349701958964726 1.0 1.0 8 P06748,Q9BUR4,O60832,Q01970 4 +Abnormal vascular physiology 0.3245760518272865 0.9629642383825489 0.3355654701530826 1.0 1.0 53 O95235,P11047,Q15056,Q8NFV4,P31749,O60568,O43709,Q9NP81,P03915,Q9UMS0 10 +Spastic paraparetic gait 0.6749309076887096 0.9598631303614164 0.3371241043992574 1.0 1.0 3 O75787 1 +Abnormal morphology of the musculature of the neck 0.4790203699181553 0.9561744735308312 0.3389840941503577 1.0 1.0 15 Q99720,Q9ULV3 2 +Spotty hypopigmentation 0.9330720530599912 0.9524884842185036 0.3408493034480373 1.0 1.0 2 P54132 1 +Corneal dystrophy 0.5671202799813699 0.9509648312819904 0.341622229052287 1.0 1.0 5 Q13868 1 +Developmental glaucoma 0.4485127472329694 0.9490582004277748 0.3425910121110278 1.0 1.0 30 P08708,P60866,P18077,P61353,P62854,P31749,P62857,P62081,P62847,P39019,P62899,P32322,P61313,P62244 14 +Pulmonic stenosis 0.448412524897935 0.9484238978571544 0.3429136981832024 1.0 1.0 30 O95235,P62140,O60826,Q15056,O43819,P61353,Q8NFV4,P60953,O60216,O43709 10 +St segment elevation 0.6716781677738523 0.9474963658579204 0.3433859072059364 1.0 1.0 3 Q9HD47 1 +Abnormal st segment 0.6716781677738523 0.9474963658579204 0.3433859072059364 1.0 1.0 3 Q9HD47 1 +Chromosomal breakage induced by ionizing radiation 0.6105838460690391 0.9469767480806692 0.3436506274528428 1.0 1.0 4 P31749 1 +Third degree atrioventricular block 0.6714738072525986 0.9467201110113 0.3437814197540723 1.0 1.0 3 Q7LG56 1 +Abnormal scapula morphology 0.3266809511043629 0.9466317935797992 0.3438264371264612 1.0 1.0 55 P18077,P62857,P39019,Q7RTS9,A6NHR9,P08708,O75340,P11047,Q06124,Q06210,P62081,P61353,P62847,P62899,P60866,Q15427,P61313,Q15738,P62244 19 +Syncope 0.4748479391308241 0.9462209163848088 0.3440359199185785 1.0 1.0 12 P31749,Q12824,Q99996,Q9HD47 4 +Decreased circulating iga level 0.5103803483072374 0.9456150130176222 0.3443449840378298 1.0 1.0 8 Q969N2,P54132 2 +Ankle clonus 0.4760699994288911 0.9430117507943692 0.3456748924741044 1.0 1.0 14 Q969N2,O75787,P42858,Q9NP72 4 +Accelerated skeletal maturation 0.4707367973735403 0.940768002726366 0.346823761572594 1.0 1.0 10 Q15022,Q96L73,P10412 3 +Food allergy 0.6082343134300873 0.937517570634867 0.3484923899319705 1.0 1.0 4 Q9Y5S9,O95394 2 +Rectal fistula 0.5261150152483319 0.9367781905763451 0.3488726660616361 1.0 1.0 7 O15160 1 +Intestinal fistula 0.5261150152483319 0.9367781905763451 0.3488726660616361 1.0 1.0 7 O15160 1 +Infantile axial hypotonia 0.472867242328835 0.9359652837514474 0.3492910623850003 1.0 1.0 12 Q9UGM6 1 +Meningioma 0.5421774337670802 0.934895389864091 0.3498422131738721 1.0 1.0 6 P31749 1 +Hemifacial spasm 0.6068242420541583 0.9318464888419774 0.3514158653540908 1.0 1.0 4 P31749 1 +Osteosarcoma 0.4567012561679546 0.9307934869946846 0.351960399389319 1.0 1.0 27 P08708,P60866,P18077,P42771,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 12 +Bladder diverticulum 0.4883999011625189 0.9300327484283496 0.3523541288866489 1.0 1.0 9 Q8NFV4,Q15056,O43709 3 +Abnormal circulating ige level 0.5244099328087141 0.9290555701622198 0.3528602882505276 1.0 1.0 7 O43909,P78536 2 +Slow decrease in visual acuity 0.488126649048983 0.9286972058543188 0.353046029219533 1.0 1.0 9 P31749,P03915,O95140 3 +Brain stem compression 0.6663381261004572 0.9272413420240344 0.3538012422353651 1.0 1.0 3 P31749 1 +Intracranial meningioma 0.6663381261004572 0.9272413420240344 0.3538012422353651 1.0 1.0 3 P31749 1 +Ear pain 0.6663381261004572 0.9272413420240344 0.3538012422353651 1.0 1.0 3 P31749 1 +Hypothalamic hypothyroidism 0.6663381261004572 0.9272413420240344 0.3538012422353651 1.0 1.0 3 P31749 1 +Neuralgia 0.6663381261004572 0.9272413420240344 0.3538012422353651 1.0 1.0 3 P31749 1 +Progressive pulmonary function impairment 0.6663381261004572 0.9272413420240344 0.3538012422353651 1.0 1.0 3 P31749 1 +Transient global amnesia 0.6663381261004572 0.9272413420240344 0.3538012422353651 1.0 1.0 3 P31749 1 +Decreased circulating follicle stimulating hormone concentration 0.6663381261004572 0.9272413420240344 0.3538012422353651 1.0 1.0 3 P31749 1 +Head tremor 0.4729190022827262 0.923886225938317 0.355545555252448 1.0 1.0 15 Q9ULV3 1 +Abnormal shoulder morphology 0.4308049807769723 0.923692367357915 0.3556465071600478 1.0 1.0 33 Q9NXH9,Q6ZXV5,O75175,Q15056,Q8NFV4,P42858,O43709,Q7RTS9,Q9BPU6 9 +Decreased activity of mitochondrial complex iv 0.4727670581846451 0.9220379041558178 0.3565088047879463 1.0 1.0 16 Q96RP9,P20674,Q969Y2 3 +T lymphocytopenia 0.4664007744065497 0.9186382503537642 0.3582848180092601 1.0 1.0 10 Q7L590,O43909,O60934 3 +Hypoplastic ilia 0.4662897571385053 0.9180728131955402 0.3585807469520132 1.0 1.0 10 Q7RTS9,Q9Y2D4,Q99575 3 +Severe viral infection 0.5216505313052857 0.9165756173039498 0.3593650660941503 1.0 1.0 7 Q7L590,P54132 2 +Abnormal brain lactate level by mrs 0.4657563874144798 0.9153570678954414 0.3600042088841109 1.0 1.0 10 P03915 1 +Colorectal polyposis 0.4853802214402571 0.915290483519102 0.3600391536885499 1.0 1.0 9 P31749 1 +Tongue thrusting 0.6022749262757575 0.9135810991076933 0.3609370017079505 1.0 1.0 4 P51608,Q05086 2 +Abnormality of bladder morphology 0.4662424897127841 0.909092373225684 0.3633013680990244 1.0 1.0 11 Q8NFV4,Q15056,O43709 3 +Abnormality of vitamin b12 metabolism 0.4646660682447631 0.9010365690574376 0.367568876550719 1.0 1.0 11 Q4G176,P22033,P41440 3 +Elevated hemoglobin a1c 0.6592279855247373 0.9003710845599251 0.3679228034155 1.0 1.0 3 Q96MF7,Q9UKG1 2 +Addictive behavior 0.4814972511438735 0.8963896103710991 0.3700447143046288 1.0 1.0 9 P42858 1 +Aplasia of the fingers 0.4358811131814393 0.895995318665172 0.3702552634688469 1.0 1.0 31 P60866,P18077,Q15427,P61353,P62847,P62857,P62081,P62899,P61313,O75962,P62244 11 +Increased serum lactate 0.4115275551294689 0.8925663916180657 0.3720894238581755 1.0 1.0 107 P00505,Q00325,Q9UBX3,Q969Y2,P11498,Q9Y3D3,Q8NI60,Q9UGM6,Q9NYY8,Q07021,P19404,Q8TCS8,Q99797,Q02218,Q8IUX1,P51608,P08559,P28331,Q9H078,Q96CU9,P14927,Q5T160,P20674,Q9BW92,P09622,Q9BSH4,Q86Y39,Q9H845,P08574,P03915,Q96RP9,Q5JTZ9,O43819,Q6P4A7,Q7LG56,Q9P0J0,Q53H12,Q16795,O14949 39 +Hyperventilation 0.5324223114642841 0.8923043651040277 0.3722298152098251 1.0 1.0 6 Q9ULV3 1 +Gynecomastia 0.4655847953574802 0.8894651695075674 0.3737531342221847 1.0 1.0 19 Q9Y4W2,P51608,P31749,Q9NW13,Q8NI60 5 +Abnormal metabolism 0.3131784150040484 0.8871837963398141 0.374979954811889 1.0 1.0 51 O60762,O75340,P10515,P22033,Q4G176,Q96C23,Q9BT22,P30038,Q9H9E3,P46977,P41440,Q8N511,Q9Y3A5,O75787 14 +Epidermal acanthosis 0.4632931201483534 0.8866717662564404 0.3752556433050393 1.0 1.0 12 O15446,Q9H4L7,Q06136,P31749,P15924,P14923,P16615 7 +Pain in head and neck region 0.5310932559237155 0.8865217742634797 0.3753364260704213 1.0 1.0 6 P31749 1 +Intracranial hemorrhage 0.4595002726967463 0.8863077435003112 0.3754517174711034 1.0 1.0 23 Q8NBJ5,P36957,Q12824,P23786,P05165,P26440,O60333,P31749,Q92947 9 +Depletion of mitochondrial dna in muscle tissue 0.5518609698458039 0.8859838256188468 0.3756262430826769 1.0 1.0 5 P12235,Q7LG56,Q9UBX3 3 +Abnormality of the scrotum 0.3130350807434506 0.8857753815750687 0.3757385783593152 1.0 1.0 51 Q9NXH9,O75175,P46100,O15160,Q9NP72,P31749,Q9Y3E5,P42858,Q9H488,Q9H0U9,Q9H9Y6,P46977,Q9BPU6 13 +Duplication of thumb phalanx 0.4521508351942588 0.8855736401294533 0.3758473212051894 1.0 1.0 26 P08708,P60866,P18077,P34897,P61353,P62854,P62857,P62081,P62847,P39019,P62899,P61313,P62244 13 +Facial hemangioma 0.5304789387562826 0.8838506820884443 0.3767768229649713 1.0 1.0 6 O60826 1 +Fibular aplasia 0.6546469862372688 0.8831234224239406 0.3771695903508378 1.0 1.0 3 O75369 1 +Coronal cleft vertebrae 0.6544028950542835 0.8822059054015021 0.3776654690397327 1.0 1.0 3 P36776,O75369 2 +Aniridia 0.4623675562617063 0.8819327323573577 0.377813184958395 1.0 1.0 12 O60333,P36957,P31040,Q9UBC2 4 +Abnormal number of erythroid precursors 0.4511081770366468 0.879449805949783 0.3791574371963084 1.0 1.0 26 P08708,P60866,P18077,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 11 +Abnormal circulating serine concentration 0.5934555590928966 0.8783182534347425 0.3797710327122665 1.0 1.0 4 P78330 1 +Decreased circulating cortisol level 0.4773939606124761 0.8764892674519063 0.38076410843769 1.0 1.0 9 P31749 1 +Oculomotor nerve palsy 0.5484222964683134 0.8714288940349473 0.3835200149645095 1.0 1.0 5 P31749 1 +Fibular hypoplasia 0.547790842324619 0.8687600480153299 0.3849783896078431 1.0 1.0 5 Q9NWH9 1 +Decreased activity of the pyruvate dehydrogenase complex 0.459499619044993 0.8678506416983348 0.3854761025754654 1.0 1.0 21 P10515,Q9BSH4,P08559,P28331,Q96CU9,Q9P0J0 6 +Abnormality of the intervertebral disk 0.4580925062362591 0.8675897300726293 0.3856189705912201 1.0 1.0 11 P62140,O43909,Q7LG56,Q9NPF4 4 +Periodontitis 0.4560337935946208 0.8661093727646003 0.3864301857457033 1.0 1.0 10 Q9BUR4,P61011,O60832,Q5JRA6 4 +Lumbar hyperlordosis 0.4602327659229232 0.865346203391163 0.3868487985215383 1.0 1.0 20 Q7RTS9,O43909,O95140 3 +Abnormal blood inorganic cation concentration 0.373736132096456 0.8644746732305443 0.3873271874589852 1.0 1.0 41 Q969N2,P36957,Q15056,O60333,P53680,Q8NFV4,Q96L73,O43709,Q9NP81,O75962,P78347,P55084 12 +Recurrent paroxysmal headache 0.455689808573406 0.8643764481035212 0.3873811265211495 1.0 1.0 10 O60333,P36957,P03915,P31040 4 +Proximal femoral metaphyseal irregularity 0.6495778045838478 0.8641012250218788 0.38753228612202 1.0 1.0 3 P61011,Q9Y3A5 2 +Triphalangeal thumb 0.4484289843335702 0.8637597881294586 0.3877198620199951 1.0 1.0 26 P08708,P60866,P18077,Q15427,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 12 +Aplasia hypoplasia of the tongue 0.5894572713464716 0.8624012471676114 0.3884667544846161 1.0 1.0 4 Q9UBM7,P48651 2 +Microglossia 0.5894572713464716 0.8624012471676114 0.3884667544846161 1.0 1.0 4 Q9UBM7,P48651 2 +Skin tags 0.4579049736762023 0.8590766107803409 0.3902982504255901 1.0 1.0 21 P31749,O60826,Q96S52,O15160 4 +Reduced circulating prolactin concentration 0.5876347660723765 0.8551613638863176 0.392461822058161 1.0 1.0 4 P31749,Q12824 2 +Abnormal circulating igm level 0.4597680256671791 0.8533866380786549 0.393444928889318 1.0 1.0 17 Q969N2,O43909,Q13724,P54132 4 +Progressive external ophthalmoplegia 0.4548746310886052 0.8513078641671864 0.394598357530824 1.0 1.0 11 Q9BQP7,Q07021,Q7LG56,P03915 4 +Facial cleft 0.5430607609333402 0.8488088163304564 0.3959876835875331 1.0 1.0 5 O15160 1 +Dolichocephaly 0.378303034512127 0.8460199813668973 0.3975415975841092 1.0 1.0 40 O75175,P46100,P54132,Q9Y2D4,P31749,Q96L73,Q7RTS9 7 +Abnormal size of pituitary gland 0.542021431820481 0.8444348731526166 0.3984264420400267 1.0 1.0 5 P31749 1 +Abnormal nasal base 0.4534436771747749 0.8440878821670643 0.3986202986593936 1.0 1.0 11 Q12824,Q13868 2 +Aplasia hypoplasia of the tragus 0.6438480096501908 0.8426857805287118 0.3994042018334838 1.0 1.0 3 Q5SRE5,A6NHR9 2 +Abnormality of the tragus 0.6438480096501908 0.8426857805287118 0.3994042018334838 1.0 1.0 3 Q5SRE5,A6NHR9 2 +Neoplasm of striated muscle 0.4509239596411928 0.8404391677320607 0.4006621960303445 1.0 1.0 10 O60934 1 +Decreased fertility in males 0.4538593426933598 0.8324546305934214 0.4051523767735983 1.0 1.0 13 P54132 1 +Hemivertebrae 0.4545036081549878 0.8310272120081245 0.40595825693469 1.0 1.0 14 O60826,Q15125 2 +Abnormality of pancreas physiology 0.3303902226245774 0.8302267661089611 0.4064105846667156 1.0 1.0 46 P05165,P22033,Q4G0N4,Q9NQH7,P42771,Q3LXA3,P53680,Q9Y3E5,P03915,P14174,Q9Y3A5,Q9UKG1 12 +Thick corpus callosum 0.6402940388295737 0.8294510878815351 0.4068492032023425 1.0 1.0 3 O75175 1 +Abnormal circulating follicle stimulating hormone concentration 0.5015623006307464 0.8264926950389563 0.4085246602099881 1.0 1.0 7 P31749 1 +Abnormal mean corpuscular volume 0.4420161348131523 0.8264862116684296 0.4085283365097882 1.0 1.0 26 P08708,P60866,P18077,P62244,P61353,P62854,P62857,P62081,P62847,P39019,P62899,P61011,Q8NBF2,P61313,Q9Y3A5 15 +Amblyopia 0.4526705188756793 0.820016450474681 0.4122067292680809 1.0 1.0 19 O75962,Q9UGM6 2 +Ketonuria 0.4480476745018746 0.8169809202609571 0.4139393317113653 1.0 1.0 11 P55809,Q96RQ3,Q96EY8,Q9HCC0,Q92947 5 +Subsarcolemmal accumulations of abnormally shaped mitochondria 0.577375565610861 0.8146010319247815 0.4153007195909555 1.0 1.0 4 P12235,Q8TCS8,Q9H1K1 3 +Patellar dislocation 0.4480287466390591 0.8126744248426625 0.4164047482268833 1.0 1.0 22 Q6ZXV5,Q15056,Q9Y2D4,Q8NFV4,O43709,P78347,Q15125 7 +Gastrointestinal carcinoma 0.4088189891533016 0.8119133613184503 0.4168413470653953 1.0 1.0 34 P60866,P18077,Q07812,P61353,P31749,P62857,P62081,P62847,P62899,P61313,P62244 11 +Abnormal intraocular pressure 0.5340207585982735 0.8108923708765632 0.4174274818573702 1.0 1.0 5 P04439,P29992 2 +Chorioretinal atrophy 0.5758672699849186 0.8086674557681861 0.4187064525188457 1.0 1.0 4 P04181,P35222,P40939 3 +Metaphyseal dysplasia 0.4488775576678818 0.8071857744704086 0.4195594602763925 1.0 1.0 13 Q7RTS9 1 +Scarring alopecia of scalp 0.5748608773517451 0.8047128003406666 0.4209854312383809 1.0 1.0 4 Q15125 1 +Abnormal circulating serine family amino acid concentration 0.4490546347413375 0.8032174058438477 0.4218490867702984 1.0 1.0 14 P05165,P22033,P78330,Q9Y617,P30038 5 +Hepatic necrosis 0.462020708121553 0.8026896930375637 0.4221541117427618 1.0 1.0 9 Q8NBF2,Q9NWH9,P40939,P38117 4 +Facial capillary hemangioma 0.6323703547436655 0.8000870844676956 0.4236603436550281 1.0 1.0 3 Q9UBM7 1 +Open bite 0.4492592236272505 0.7983358476133968 0.4246756206022075 1.0 1.0 17 Q15056,O15160,Q8NFV4,O43709,Q9H9Y6 5 +Secondary growth hormone deficiency 0.5730710725259646 0.7976886704552314 0.4250511801082139 1.0 1.0 4 P31749 1 +Heteronymous hemianopia 0.5300043374908582 0.7941444818910183 0.4271113245451181 1.0 1.0 5 P31749 1 +Lower limb hyperreflexia 0.4475990075365689 0.7931156837797833 0.4277104259022855 1.0 1.0 19 O60762,P31040,P10515,Q8WVX9,O95394,Q9NZJ4,P51608,Q15233,Q05086,Q5T440 10 +Insomnia 0.4479586773430553 0.7921467857584709 0.4282750927238368 1.0 1.0 16 Q8NFV4,P42858,Q15056,O43709 4 +Normochromic anemia 0.4385045685977722 0.7919968727428223 0.4283624996901753 1.0 1.0 25 P08708,P60866,P18077,P46777,P61353,P47985,P62854,P62857,P62081,P62847,P39019,P62899,P61313,P62244 14 +Late onset 0.4597480852050841 0.7918935665985658 0.4284227385035981 1.0 1.0 9 P17096,Q9Y6M1,P62263,P31483 4 +Decreased circulating igg level 0.4435174379957716 0.7866025248865263 0.4315145807704508 1.0 1.0 12 O43909,P54132 2 +Abnormal prolactin level 0.5281643851150235 0.7864937677180351 0.4315782688390499 1.0 1.0 5 P31749,Q12824 2 +Optic disc pallor 0.306094669198284 0.7833401119390255 0.4334274141379095 1.0 1.0 53 O95140,O43676,Q86Y39,Q9H6K4,Q8IUX1,P28331,Q9NPL8,Q96CU9 8 +Prolonged qtc interval 0.6270327194633121 0.7804254926258334 0.4351404674946617 1.0 1.0 3 Q99996 1 +Central hypothyroidism 0.4386830759251916 0.7796322746687853 0.4356073530399322 1.0 1.0 10 P31749,Q12824,Q9NW13 3 +Abnormal urine carboxylic acid level 0.4403027685102882 0.7792714840410596 0.4358198088131337 1.0 1.0 23 P55809,P05165,O60333,Q9H6K4,Q9H078 5 +Beaking of vertebral bodies 0.4418895411644272 0.7784879847457163 0.4362813872403932 1.0 1.0 12 Q7RTS9 1 +Hypoplasia of the frontal lobes 0.4378878814816476 0.7757188633511549 0.4379149996073499 1.0 1.0 10 O60762,Q86XL3,Q96C36,Q9UBM7,P22570 5 +Athetosis 0.4442976475652722 0.7726619718340858 0.4397224579820444 1.0 1.0 17 Q99798,Q92947,Q96CU9,Q9UGM6,Q9BPU6,O14949 6 +Complex febrile seizure 0.876997286704854 0.7708473475817395 0.4407974189878632 1.0 1.0 2 Q8WVX9 1 +Abnormal magnesium concentration 0.5038648720118217 0.7693709788589242 0.4416731117794805 1.0 1.0 6 P53680 1 +Overlapping toe 0.4398623566169903 0.7682399764315224 0.4423446274260998 1.0 1.0 22 Q15125,O60826,P60953,Q86W42 4 +Abnormal globus pallidus morphology 0.4714951698501504 0.7655683392106893 0.4439331891124207 1.0 1.0 8 Q92947,O43819,P10515,P22033 4 +Decreased circulating acth level 0.5230583827634636 0.7653372639572164 0.4440707398817973 1.0 1.0 5 P31749 1 +Laryngotracheomalacia 0.5646074000363919 0.7646359487267542 0.4444883565114292 1.0 1.0 4 Q8N766,O75369 2 +Jerky head movements 0.8739825143201654 0.7613341404556863 0.4464575137385771 1.0 1.0 2 Q969N2 1 +Scrotal hypoplasia 0.4413395768746767 0.7602390726321966 0.4471116934328183 1.0 1.0 19 P46100,Q9NP72,O15160,Q9UBM7,Q6NUK1,Q9H0U9,Q9H9Y6,P46977 8 +Secondary amenorrhea 0.440445411630764 0.7597535732105747 0.4474018990028998 1.0 1.0 14 Q9UI10,O75616 2 +Abnormal cerebrospinal fluid metabolite concentration 0.4697359373400301 0.7575996912852029 0.4486906650525668 1.0 1.0 8 P08559,Q8TCS8 2 +Visual field defect 0.3217902175589011 0.7558836943032168 0.4497189310052727 1.0 1.0 46 O75695,P60866,Q12824,P10515,O95140,Q9H6K4,O60220,P31749,P22570,Q99798,P03915,Q5T440 12 +Abnormal circulating pyruvate family amino acid concentration 0.438315101131179 0.7531295214560804 0.451372085968502 1.0 1.0 21 P20674,Q8IUX1,P11498,P08559,P03915,P30038,Q9P0J0 7 +Sick sinus syndrome 0.8712692191739473 0.7527981475823305 0.4515712201035673 1.0 1.0 2 Q9HD47 1 +Cheilitis 0.5197960301835721 0.7518800849650739 0.4521231754550388 1.0 1.0 5 P54132 1 +Abnormal circulating glycine concentration 0.4363802474938655 0.7511837299156606 0.4525420905212112 1.0 1.0 12 Q9Y617,P05165,P22033,P30038 4 +Abnormal social behavior 0.336431187342594 0.7503705766741596 0.4530315467555659 1.0 1.0 72 O43909,Q9Y3C6,P19404,O43676,Q86Y39,Q8IUX1,O75380,Q8NFV4,P28331,Q9NPL8,O43709,Q96CU9,Q9P0J0,Q15125 14 +Shawl scrotum 0.4986313316788722 0.7471953893598385 0.4549456267991658 1.0 1.0 6 P46100 1 +Increased serum pyruvate 0.3885355826060245 0.7467040563446766 0.4552422206908952 1.0 1.0 36 O43676,Q86Y39,Q8IUX1,P11498,O75380,P08559,P28331,Q9NPL8,Q96CU9 9 +Honeycomb lung 0.6177275634913926 0.746398232282713 0.4554268867883664 1.0 1.0 3 Q86TI2 1 +Crackles 0.6177275634913926 0.746398232282713 0.4554268867883664 1.0 1.0 3 Q86TI2 1 +Abnormal cochlea morphology 0.6174546944480384 0.7454054401603631 0.4560266561317285 1.0 1.0 3 O60220 1 +Onycholysis 0.5180926195321485 0.7448730279890275 0.4563484819140857 1.0 1.0 5 P10321,O15446 2 +Abnormal tracheobronchial morphology 0.3195672077374552 0.7412326322052668 0.4585524007249328 1.0 1.0 63 O43909,Q15056,Q03518,O15160,P54132,O95394,Q86TI2,P57076,Q8NFV4,O60934,O43709,Q9H9Y6,O60832,Q15125 14 +Generalized hypopigmentation of hair 0.4307497033319717 0.7408105712099513 0.4588083046238544 1.0 1.0 10 Q05086,Q9BUR4,Q13724,O60832 4 +Progressive macrocephaly 0.8673500150738542 0.7405127706714136 0.4589889151130348 1.0 1.0 2 P31749 1 +Thoracic kyphosis 0.4376584321812951 0.7391296595679793 0.459828268283154 1.0 1.0 18 Q7RTS9 1 +Abnormality of the cheek 0.3120555439855966 0.7378974915358526 0.4605767434248391 1.0 1.0 59 P10412,P62140,O43909,O60826,Q96S52,O15160,Q9BZK7,Q9H9Y6 8 +Abnormal reticulocyte morphology 0.4059196049365104 0.73556516949986 0.4619953659815299 1.0 1.0 32 P08708,P60866,P18077,P62244,P61353,P62854,P62857,P62081,P62847,P39019,P62899,Q8NBF2,P61313,Q9Y3A5 14 +Enlarged metaphyses 0.864938197166105 0.7329792180911123 0.4635711046870676 1.0 1.0 2 O43909 1 +Low anterior hairline 0.3023065904074652 0.731211535519935 0.464649955242107 1.0 1.0 54 P60866,Q12824,O15160,Q9NP72,P18077,P61353,O60934,P62857,P62081,P62847,O60216,P62899,Q9H9Y6,P61313,P62244 15 +Pain insensitivity 0.5555160261524661 0.729456745608216 0.4657223173044842 1.0 1.0 4 P51608,O15269 2 +Recurrent urinary tract infections 0.3857549425515952 0.7283962293908415 0.4663710707720023 1.0 1.0 36 P46100,P54132,Q8NFV4,O60934,O43709,Q86W42 6 +Polyuria 0.5133534759878473 0.7254517032667276 0.4681749638421264 1.0 1.0 5 Q9NQ48,Q9NP81 2 +Chorioretinal coloboma 0.4455684232552687 0.7253043721218394 0.4682653241173762 1.0 1.0 9 P31749 1 +Premature loss of teeth 0.4317124009233387 0.7216215106807332 0.4705272103463278 1.0 1.0 13 Q969N2,O60832,Q5JRA6,Q9NW13 4 +Exercise intolerance 0.384621144136117 0.7209748390139252 0.4709249954050789 1.0 1.0 36 Q9BQP7,Q07021,P23786,P03915,P24928,Q7LG56,Q8IUX1,Q9Y285,Q9H845,P40939,Q92947,Q8NI60,P30038,P55084 14 +Craniofacial dysostosis 0.5122315477900865 0.7208702747470092 0.4709893331104724 1.0 1.0 5 P62854,Q6NUK1,O15160 3 +Abnormality of the inner ear 0.4291712797137417 0.7158489792407754 0.4740846052513137 1.0 1.0 12 P31749,Q9H9Y6,O15160 3 +Abnormality of the basal ganglia 0.3596129161080794 0.7152502317053847 0.4744544351081834 1.0 1.0 88 P24928,Q969Y2,Q8NI60,Q9NYY8,O75340,Q9ULK4,P10515,Q8TCS8,P19404,P08559,P42858,P28331,Q9H078,Q92947,Q96CU9,Q9BSH4,P03915,P23786,P22033,Q96RP9,O43819,O60220,Q9P0J0,Q99700,P22570,Q9P2R7,Q16795,Q99986 28 +Abnormal fingernail morphology 0.2932855552413699 0.7151805745490822 0.4744974707026856 1.0 1.0 50 Q15022,P62140,O75367,Q12824,O60826,Q15056,P48651,Q8NFV4,Q96L73,O43709,Q9H488,O60832,Q15125 13 +Deep philtrum 0.432905666095593 0.7148473157424959 0.4747033943712746 1.0 1.0 18 Q969N2,P62140,Q96S52,Q8N201,Q96L73 5 +Bronchitis 0.4429296490781426 0.7130726230002868 0.475800819308223 1.0 1.0 9 P54132,Q03518,P57076 3 +Abnormal hypothalamus physiology 0.4904828962338684 0.7129333734299345 0.4758869865261261 1.0 1.0 6 P31749 1 +Pulmonary edema 0.5509058226487621 0.7117577504511482 0.4766147994190646 1.0 1.0 4 Q13724 1 +Phimosis 0.5097408700616696 0.7107226113417401 0.4772561449937522 1.0 1.0 5 Q96L73 1 +Aplasia hypoplasia affecting the anterior segment of the eye 0.4094400273568278 0.7101483420321535 0.4776121510789775 1.0 1.0 30 P36957,P11047,Q15056,O60333,Q8NFV4,O43709,O95202,P78347,Q9UBC2 9 +Axial muscle weakness 0.4891117027250732 0.7072016601034365 0.4794411670584404 1.0 1.0 6 P11047 1 +Abnormal vestibulo ocular reflex 0.8558938800120494 0.7049165231986418 0.4808621868187201 1.0 1.0 2 P41440 1 +Aplasia hypoplasia of the cerebral white matter 0.4407380744998941 0.7029553536837009 0.4820835732717317 1.0 1.0 9 P03915,Q9UGM6 2 +Hand muscle weakness 0.4273046991894537 0.7000746149636159 0.4838807080313221 1.0 1.0 13 P11047,P31483 2 +Peripheral pulmonary artery stenosis 0.4257951061618104 0.6994652868170588 0.4842612995225748 1.0 1.0 12 P62140,Q8NFV4,Q15056,O43709 4 +Optic neuropathy 0.4108544477339348 0.6985690432416707 0.4848213956108971 1.0 1.0 29 P03915,O43676,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9,Q9P0J0 9 +Pancreatitis 0.4249937623445637 0.6966916707915052 0.485995772477712 1.0 1.0 23 P03915,P05165,Q3LXA3 3 +Abnormal circulating estrogen level 0.4248528727787103 0.6949125714563085 0.487110093786848 1.0 1.0 12 P31749,Q12824 2 +Muscle fiber inclusion bodies 0.4212012496008254 0.6947893598187768 0.4871873172410601 1.0 1.0 10 O75340,O43676 2 +Simple ear 0.5052892116155164 0.6926673824044279 0.4885183130893351 1.0 1.0 5 Q96KP1,O60231,Q16531 3 +Rhizomelia 0.4241261623608053 0.6914072259081188 0.4893096643915648 1.0 1.0 12 Q7RTS9 1 +Chromosomal breakage induced by crosslinking agents 0.5453996983408762 0.6907522311538917 0.4897212595615714 1.0 1.0 4 O15360,Q9BXW9,Q9NVI1 3 +Chronic hepatic failure 0.5453576494362494 0.6905923954961549 0.4898217277026271 1.0 1.0 4 P55084 1 +Vertebral clefting 0.4849869714374899 0.6900221138048803 0.4901802808940929 1.0 1.0 6 P36776,O60216,O75369 3 +Leukemia 0.3189426934568378 0.6889400303102955 0.4908610070949253 1.0 1.0 66 P18077,Q96L73,P62857,P39019,Q9Y3A5,P08708,P11766,Q06124,P42771,O60934,P62081,O60832,Q13492,Q07812,P61353,P62847,P62899,P60866,P46100,P54132,P61011,P61313,P62244 23 +Abnormal muscle fiber type distribution 0.4225408047940636 0.6837785069358319 0.4941150405857775 1.0 1.0 12 O75340,P11047,Q8TCS8 3 +Episodic hyperhidrosis 0.4365243608107731 0.6836130890755939 0.4942195172182289 1.0 1.0 9 O60333,P36957,P31040,Q02978 4 +Abnormal foramen magnum morphology 0.5999293893936083 0.6823038259773481 0.4950468543095621 1.0 1.0 3 O75369 1 +Urogenital fistula 0.4180267781866971 0.6796757294946862 0.4967098070268494 1.0 1.0 10 O15160 1 +Sparse and thin eyebrow 0.4216408387833089 0.6794592499290443 0.4968469191238753 1.0 1.0 12 P62857 1 +Vaginal fistula 0.434911811010819 0.6762506166210405 0.4988815407041047 1.0 1.0 9 O15160 1 +Progressive distal muscle weakness 0.5979683373402839 0.6753294788802745 0.499466458966205 1.0 1.0 3 P55084 1 +Progressive night blindness 0.4247678126023562 0.6738488908873116 0.5004073881625863 1.0 1.0 18 O75695,Q15555,Q6P2Q9,Q13099,P50213,Q92620,O94906,Q8TC12,O75643,O43837 10 +Persistent head lag 0.4662929762984834 0.6728015505377931 0.5010735511891178 1.0 1.0 7 P51608 1 +Abnormality of the humerus 0.422649885785564 0.6678726349698424 0.5042148965873321 1.0 1.0 15 O75367,O75369,P36776,P48651,O00116,Q6ZRS2,O15228,Q7RTS9,Q9Y5S9 9 +Abnormality of lower limb epiphysis morphology 0.4232031011217022 0.6673032314103395 0.5045784627302727 1.0 1.0 19 Q7RTS9,O43909 2 +Short chin 0.4200786068302475 0.6651750680076108 0.5059385251501094 1.0 1.0 13 O75962 1 +Abnormality of the radial head 0.4137297801230449 0.6593771359211147 0.5096536205615059 1.0 1.0 10 O43909 1 +Broad forehead 0.3457038570311 0.6567501033553131 0.5113416123436794 1.0 1.0 41 Q15022,O60826,Q15056,P48651,Q8NFV4,Q96L73,O43709,Q8NI27,Q86W42 9 +Mitochondrial myopathy 0.3789772241385993 0.6529889701538568 0.5137633893019307 1.0 1.0 35 P19404,P03915,O43676,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9 9 +Fetal distress 0.4055702971671766 0.6516530097744017 0.5146250425843861 1.0 1.0 28 O43676,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9 7 +Narrow palpebral fissure 0.4193662867416065 0.6506245516794985 0.5152888776546412 1.0 1.0 20 Q9NXH9,Q9BZK7,Q8N201 3 +Subvalvular aortic stenosis 0.4947990817668124 0.6505667071677932 0.5153262275417396 1.0 1.0 5 Q06124,O43683 2 +Abnormal left ventricular outflow tract morphology 0.4947990817668124 0.6505667071677932 0.5153262275417396 1.0 1.0 5 Q06124,O43683 2 +Pallor 0.2894770174826147 0.6483470804260076 0.5167604895652911 1.0 1.0 52 P36957,P60866,P18077,O94906,O60333,P61353,P62857,P62081,P62847,P62899,Q99798,P22570,P61313,P62244 14 +Abnormal circulating proteinogenic amino acid concentration 0.3828436596286222 0.6481462221763713 0.5168903806409251 1.0 1.0 34 P20674,P05165,P22033,P09622,O15382,Q96EY8,Q4G0N4,Q96RQ3,Q9HCC0,P35270,P78330,Q9Y617,P30038,P41440 14 +Abnormal cardiac test 0.419250988005876 0.6475689456347292 0.5172637881501918 1.0 1.0 19 Q9HD47,Q99996,Q7LG56,Q969Y2,P51608,P40939 6 +Abnormal dermoepidermal junction morphology 0.5895584099523978 0.6456364687763477 0.5185148135723778 1.0 1.0 3 P14923 1 +Nemaline bodies 0.5334273419710494 0.645620243528949 0.5185253239085539 1.0 1.0 4 O43676 1 +Deep set nails 0.8362978595116014 0.6452131236857128 0.5187890826673149 1.0 1.0 2 Q96L73 1 +Adenocarcinoma of the intestines 0.4113974257334766 0.6436943571590017 0.5197736497830905 1.0 1.0 25 P08708,P60866,P18077,P61353,P62854,P28340,P62857,P62081,P62847,P39019,P62899,P61313,P62244 13 +Abnormal female reproductive system physiology 0.3066070041003075 0.6430913417122124 0.5201648323101133 1.0 1.0 62 Q12824,P54132,Q9UI10,O75616,O60934,P31749,Q9BZK7,Q86W42 8 +Abnormal pulmonary valve physiology 0.3770438203790708 0.6410740641974537 0.5214745639829983 1.0 1.0 35 O95235,P62140,O60826,Q15056,O43819,Q86TI2,P61353,Q8NFV4,P60953,O60216,O43709 11 +Abnormal fundus autofluorescence imaging 0.588125691112492 0.6406142505961788 0.5217733385157497 1.0 1.0 3 P50213 1 +Malar prominence 0.5310305645095879 0.6366807826837146 0.5243327936499145 1.0 1.0 4 Q9Y4W2 1 +Aplasia hypoplasia involving the vertebral column 0.4166447803296093 0.6358600035113783 0.5248676738107378 1.0 1.0 16 Q7RTS9 1 +Decreased proportion of cd4 positive helper t cells 0.4716056280041373 0.6349841051282509 0.5254387816875623 1.0 1.0 6 O43909 1 +Excessive wrinkled skin 0.4084700443937556 0.6347936396252044 0.5255630120741532 1.0 1.0 10 Q06124,Q9BZK7,O60832,P32322 4 +Increased serine family amino acid in urine 0.4570940341215164 0.633967988894449 0.52610171322262 1.0 1.0 7 P05165,P30038 2 +Facial hyperostosis 0.8323786554115061 0.6334671362230103 0.5264286352373553 1.0 1.0 2 P31749 1 +High anterior hairline 0.4135419034501634 0.6302813328656406 0.5285105340290275 1.0 1.0 22 P62140,Q96L73,Q9BZK7,Q86W42 4 +Abnormality of the sense of smell 0.4156682328625584 0.6289532954000773 0.5293796331339311 1.0 1.0 18 P31749,P42858,O95140 3 +Ureteral duplication 0.4694507129217274 0.626228338958584 0.531165181875322 1.0 1.0 6 Q96L73 1 +Lewy bodies 0.4693156511117207 0.6256806155808924 0.5315244501922414 1.0 1.0 6 Q99700,P31483 2 +Abnormal cerebral vascular morphology 0.3183168541381857 0.6249894550112279 0.5319779790276651 1.0 1.0 70 Q8NBJ5,Q12824,Q8NFV4,Q15056,P26440,P51608,O60568,O43709,Q92947,O95235,P31749,P03915,P78347,P36957,P23786,P22033,P05165,Q96RQ3,O60333 19 +Ureteral stenosis 0.4688672592430771 0.6238631292950548 0.5327174762700888 1.0 1.0 6 Q969N2 1 +Abnormal localization of kidney 0.3127498172265625 0.6216340954328756 0.5341824962044543 1.0 1.0 67 O43909,Q12824,P60866,Q15056,Q9NP72,P18077,P62244,P61353,Q8NFV4,P62857,P62081,P62847,O43709,P62899,P61313,P78347,O60832,Q86W42 18 +Delayed ability to sit 0.4139281073691085 0.6213164207864752 0.534391451562453 1.0 1.0 19 P51608,O43909,O75962,Q9BPU6 4 +Webbed neck 0.3526488917647642 0.6204420242776065 0.5349668122158908 1.0 1.0 39 P08708,P62140,P60866,P18077,Q06124,P61353,P62857,P62081,P60953,P39019,P62847,P62899,O95202,P61313,P08069,P62244 16 +Anarthria 0.45375554780754 0.620029490737862 0.5352383713596782 1.0 1.0 7 Q99720 1 +Abnormal t wave 0.4847887769253872 0.611033604295557 0.5411773336581134 1.0 1.0 5 P51608,Q99996 2 +Acute lymphoblastic leukemia 0.4117574593592598 0.6099925477310627 0.5418667441789775 1.0 1.0 18 P54132,P42771,Q07812,Q96L73,O60934 5 +Hyporeflexia of lower limbs 0.4068369767343153 0.6096789116852139 0.542074526720665 1.0 1.0 12 Q9NYY8,Q5T440,P55084,O75787 4 +Brain imaging abnormality 0.3615932438923991 0.6071914424554862 0.5437238707034286 1.0 1.0 37 Q12824,O43819,P31749,Q96L73,Q96ST3,P60953,Q9BZK7,P03915 8 +Developmental cataract 0.2933762970918378 0.6054237194265671 0.5448974947271596 1.0 1.0 57 P60866,Q8TCS8,Q9NP72,P18077,Q8WVX9,O60333,P38117,P61353,P62857,P62081,P62847,P39019,P62899,Q5SRE5,P03915,P61313,P62244 17 +Ureteral obstruction 0.4501769109237594 0.6051858083350087 0.5450555443032084 1.0 1.0 7 Q969N2 1 +Fetal onset 0.4500908046260086 0.604829926860641 0.5452920066824558 1.0 1.0 7 O95235,P62140,Q7L590 3 +Bilateral ptosis 0.4094487730725018 0.6047441252310418 0.5453490244524215 1.0 1.0 15 O43819,P11047,Q7LG56 3 +Pituitary hypothyroidism 0.4639102288109162 0.6038648350526411 0.5459335097583711 1.0 1.0 6 P31749 1 +Brisk reflexes 0.4069659024137015 0.6034320928288474 0.5462212779117672 1.0 1.0 23 Q99720,Q8NI60,Q9Y3C6,O15382 4 +Increased intervertebral space 0.8221284293035758 0.603077689082668 0.5464570079398592 1.0 1.0 2 O43909 1 +Multiple mitochondrial dna deletions 0.5772014475271323 0.6026909482072823 0.5467143043555371 1.0 1.0 3 P12235,Q7LG56 2 +Nocturia 0.5772014475271323 0.6026909482072823 0.5467143043555371 1.0 1.0 3 P12235,Q7LG56 2 +Intermittent diarrhea 0.433831639990108 0.5997210445419704 0.5486921607002095 1.0 1.0 8 Q9H9E3,P46100,P42771 3 +Abnormal circulating igg level 0.4089637149959947 0.5992419378680474 0.5490115602690888 1.0 1.0 16 O43909,Q13724,P54132 3 +Abnormality of mouth shape 0.3168272162171754 0.5989140265966667 0.5492302173119037 1.0 1.0 71 Q969N2,P62140,O43909,P11047,Q86XL3,O75175,P46100,Q9NP72,P31749,P60953,O60568,Q15125 12 +Tongue atrophy 0.5206894270966721 0.5985083192131008 0.5495008096168408 1.0 1.0 4 Q9Y6X9 1 +Abnormality of circulating glucocorticoid level 0.4042606101941247 0.5977974042377631 0.5499751229050103 1.0 1.0 12 P31749 1 +Abnormality of the posterior pituitary 0.4483385958695435 0.5976012442977384 0.5501060337805417 1.0 1.0 7 P31749 1 +Abnormal circulating proteinogenic amino acid derivative concentration 0.4053237842567244 0.5951836400645283 0.5517207247390923 1.0 1.0 23 P20674,Q8IUX1,P11498,P08559,P03915,P30038,Q9P0J0 7 +Neoplasm of the skeletal system 0.2860752573339749 0.5934905368807931 0.5528529141968708 1.0 1.0 48 P60866,O15160,P18077,P42771,P61353,P31749,P62857,P62081,P62847,O60216,P62899,Q9H9Y6,P61313,P62244 14 +Skeletal myopathy 0.4799144797651543 0.5920326595502532 0.5538287186464985 1.0 1.0 5 P40939,P55084 2 +Abnormal urinary electrolyte concentration 0.4074159510359073 0.5916145616728246 0.5541087206087614 1.0 1.0 20 Q969N2,Q15056,P53680,Q8NFV4,O43709,Q9NP81 6 +Psychomotor retardation 0.3684812119411871 0.5893638689490442 0.5556172085704267 1.0 1.0 35 P11047,P10515,P05165,Q96RQ3,P11498,P08559,Q9UMS0,Q99986 8 +Delayed fine motor development 0.3983288605393075 0.5882785583730411 0.5563453351270782 1.0 1.0 10 O75175 1 +Overlapping fingers 0.4460321125136294 0.5881251049274918 0.5564483234059134 1.0 1.0 7 Q15125 1 +Horizontal eyebrow 0.4595467864273185 0.5864096154898837 0.557600284186546 1.0 1.0 6 P78536 1 +Deeply set eye 0.3150014612493297 0.5842818702682258 0.5590306876426929 1.0 1.0 71 Q5T160,O43909,P20674,O75175,Q13868,Q9Y4W2,Q96ST3,Q9BZK7,Q86W42,Q9NPF4 10 +Abnormal circulating iga level 0.4040311555754269 0.5840334633101477 0.5591977984178955 1.0 1.0 14 Q969N2,Q13724,O95394,P54132 4 +Esophageal stricture 0.5162995363497349 0.5825103593122202 0.5602229657794378 1.0 1.0 4 O95394 1 +Decreased circulating copper concentration 0.5710566487745206 0.5816633699566702 0.5607934492503728 1.0 1.0 3 Q10567 1 +Autoamputation 0.4771743194398773 0.5814270897168716 0.5609526442360597 1.0 1.0 5 O15269,P51149 2 +Hemangioblastoma 0.4442041160071255 0.5806471361464598 0.5614782970577779 1.0 1.0 7 O60333,P36957,P31040 3 +Arachnoid hemangiomatosis 0.4442041160071255 0.5806471361464598 0.5614782970577779 1.0 1.0 7 O60333,P36957,P31040 3 +Abnormality of thalamus morphology 0.4048113732677162 0.5772866025052694 0.5637458625821885 1.0 1.0 19 P31749,O43819,Q12824,Q969Y2 4 +Fair hair 0.4754407412724445 0.5747466189738519 0.5654626735770063 1.0 1.0 5 Q13724 1 +Facial telangiectasia 0.47541013713066 0.5746288900828733 0.5655423090860083 1.0 1.0 5 P54132 1 +Focal t2 hyperintense basal ganglia lesion 0.4018019231458395 0.5718852071981233 0.5673997464032359 1.0 1.0 22 Q9BSH4,Q96CU9,P08559,P28331,P03915,Q9P0J0 6 +Congestive heart failure 0.3047647348989503 0.5706603723528184 0.5682298857702894 1.0 1.0 66 P36957,Q15056,Q00325,O43819,O60333,Q969Y2,P51608,Q8NFV4,P40939,Q9H2U2,P39019,O43709,P03915,P78347,P14923,P55084 16 +Schwannoma 0.5675055011450868 0.5696171721071939 0.5689373789104439 1.0 1.0 3 Q12824 1 +Abnormality of the humeroradial joint 0.3934658328671919 0.5664190495665872 0.5711089480306999 1.0 1.0 10 O43909 1 +Type ii diabetes mellitus 0.3380345672779664 0.5632674964168447 0.573252747695155 1.0 1.0 40 O75695,Q15056,P54132,P50213,O94906,Q92620,P17096,Q8NFV4,Q9Y6M1,O43709,P03915,P78347 12 +Hypopigmented macule 0.5107981026942625 0.5626469318728133 0.5736753272998549 1.0 1.0 4 Q9H488 1 +Preauricular skin tag 0.4014808669919253 0.5612135536415352 0.5746519643869052 1.0 1.0 18 Q96S52,O60826,O15160 3 +Spinal cord compression 0.4240967807433281 0.5588076958584961 0.5762929696812791 1.0 1.0 8 P31749,O43909 2 +Abnormality of the frontal hairline 0.318349601564129 0.5576745749055123 0.5770666223603766 1.0 1.0 75 P62140,Q12824,O15160,Q9NP72,P61353,Q96L73,P62857,O60934,P62847,Q9BZK7,P61313,Q9H9Y6,Q86W42 13 +Diastema 0.4383836687335349 0.5570340822044793 0.5775041432434211 1.0 1.0 7 O15347,P46100,Q8TC12 3 +Abnormal dental pulp morphology 0.4371950286011045 0.5522499405335319 0.580777122757314 1.0 1.0 7 Q9BUR4,O60832 2 +Fulminant hepatic failure 0.5621409808698188 0.551573045823347 0.5812409078221856 1.0 1.0 3 Q96RP9 1 +Triangular shaped phalanges of the hand 0.3120767158020937 0.5481342684375561 0.5835997119817842 1.0 1.0 72 P18077,Q96L73,P62857,Q15022,P62081,P42858,Q9BPU6,Q9NXH9,O75175,Q13868,P61353,P62847,O60216,P62899,O75962,P60866,Q15427,P61313,P62244 19 +Macular atrophy 0.4347873689458362 0.5426002463740307 0.5874050693072808 1.0 1.0 7 Q92620,P04439 2 +Ketosis 0.3974249278240114 0.542549795596231 0.587439813518847 1.0 1.0 19 P55809,P22033,P26440,Q96EY8,Q4G176,Q9HCC0,Q92947,Q7LG56,P08574,Q15046 10 +Equinus calcaneus 0.801025022610794 0.5421367631073268 0.5877242946081735 1.0 1.0 2 P55084 1 +Abnormal acetabulum morphology 0.3969726610064057 0.5418322192186561 0.5879340936776418 1.0 1.0 20 Q7RTS9 1 +Aplastic anemia 0.4043624932588837 0.5415767190235449 0.5881101334506993 1.0 1.0 9 O76094,Q5F1R6,O60934,P61011,Q9Y3A5 5 +Vitreous floaters 0.5591073582629684 0.5414535599110485 0.5881949988480455 1.0 1.0 3 P35222,P04439 2 +Hypoplastic anemia 0.8007235453723218 0.5412830890511088 0.5883124747458877 1.0 1.0 2 Q03426 1 +Thrombocytosis 0.375190967880632 0.5375079942005668 0.5909167644183635 1.0 1.0 31 P60866,P18077,P61353,P62847,P62857,P62081,P62899,P61313,P62244 9 +Abnormal drinking behavior 0.5033948637413894 0.5362599461684293 0.591778908528583 1.0 1.0 4 Q9NQ48,O76024 2 +Memory impairment 0.3391748497347592 0.5345957805906112 0.5929294019471172 1.0 1.0 39 P60866,Q12824,Q4G176,Q9UI10,P31749,P42858,Q8WVX9,P03915,P31483 9 +Decreased circulating antibody level 0.2934310320050344 0.5299409841209008 0.5961528492303176 1.0 1.0 46 Q969N2,O43909,P54132,O60934,Q13724,P14174,O75787 7 +Nonimmune hydrops fetalis 0.3799022004231319 0.5298184576688345 0.5962378065772294 1.0 1.0 29 P60866,P18077,P61353,Q9BT22,P62857,P62081,P62847,P62899,P61313,Q7L590,P62244 11 +Hydrops fetalis 0.2932264821105703 0.5284416439080732 0.5971928401787987 1.0 1.0 46 O95235,P60866,P18077,P61353,Q04446,Q9BT22,P62857,P62081,P40939,P62847,P62899,Q7L590,P61313,P62244,P55084 15 +Abnormality of circulating adrenocorticotropin level 0.4008975857719914 0.5269602871669842 0.5982211667693504 1.0 1.0 9 P31749,P46100 2 +Short fourth metatarsal 0.7952969550798805 0.5260027988105395 0.5988862623580957 1.0 1.0 2 Q96S52 1 +Abnormal neutrophil count 0.3123197369675522 0.5245656037337957 0.5998852031091444 1.0 1.0 74 P18077,P62857,Q8N5M9,Q9H9E3,Q9Y3A5,P62081,Q9H078,O95394,P61353,P62847,P62899,Q03426,P60866,Q9Y3C6,O75083,P22033,P46100,P05165,Q9BZK7,P61313,P62244 21 +Abnormal pancreas size 0.4156800129774267 0.5242251143587606 0.6001219750300335 1.0 1.0 8 Q9Y3E5,Q9Y3A5,Q9UKG1 3 +Nasogastric tube feeding in infancy 0.3836827871687046 0.5234016840935811 0.6006947524837036 1.0 1.0 10 Q8TD30 1 +Hypoplastic toenails 0.3892265772506217 0.5230947307047542 0.6009083322145123 1.0 1.0 24 Q15022,P62140,Q12824,Q15056,Q8NFV4,Q96L73,O43709,P78347 8 +Chronic neutropenia 0.44329907244738 0.5227527254449416 0.6011463416095013 1.0 1.0 6 Q9Y3C6,Q9Y3A5 2 +Abnormal ovarian morphology 0.3809137756335239 0.5214026746697367 0.6020862886291982 1.0 1.0 28 Q15056,Q15031,Q8NFV4,P51809,O75616,P31749,O43709,P78347 8 +Bone spicule pigmentation of the retina 0.3994840678116914 0.5210409477933716 0.60233824652591 1.0 1.0 9 Q15555,Q96S66,P50213,Q9NQ48,O75643 5 +Inverted nipples 0.4612039359448517 0.5207954611710536 0.6025092652779971 1.0 1.0 5 Q969N2 1 +Abnormal auditory evoked potentials 0.3820809364125144 0.5164870460512571 0.6055142840709333 1.0 1.0 10 Q13724,Q15125 2 +Cranial nerve compression 0.3810817069081705 0.5121928588969403 0.6085160404363867 1.0 1.0 10 P36957,P31040,O60333,P22626,Q02978 5 +Anemia of inadequate production 0.3053909451822305 0.5102530578544295 0.6098741850143639 1.0 1.0 71 P18077,P22830,Q3LXA3,Q9UBX3,P62857,P39019,Q15046,P41440,Q9Y3A5,P08708,Q9Y285,P62081,Q15031,P61353,P62847,P62899,Q03426,P60866,P46100,Q6P4A7,P61011,P61313,P62244 23 +Dysmetria 0.2863898850610852 0.5074102631872625 0.6118669859898982 1.0 1.0 60 Q15056,P35251,Q6P4A7,Q7LG56,Q8NFV4,Q9Y3E5,O15020,Q9NPL8,O43709,Q9UGM6,P41440,O75787 12 +Atrioventricular canal defect 0.3795517255408125 0.50564665214998 0.6131047251341355 1.0 1.0 10 O75962 1 +Upper limb spasticity 0.4104255359793206 0.5030381816572422 0.6149374279589295 1.0 1.0 8 Q5T160,Q99720 2 +Narrow face 0.3164566610631681 0.5021349396718339 0.6155726041923899 1.0 1.0 42 Q9NXH9,Q9Y281,O75175,P54132,Q8NFV4,Q96L73,Q96ST3,P42858,O43709 9 +Sprengel anomaly 0.3644811778433787 0.4992031214768692 0.6176362957861423 1.0 1.0 32 P08708,P60866,P18077,Q06124,Q15427,P61353,P62857,P62081,P62847,P39019,P62899,P61313,P62244 13 +Kinetic tremor 0.3480952970704549 0.4982277509309413 0.6183235247519954 1.0 1.0 36 P41440,O15020 2 +Broad long bones 0.3425830072281263 0.4936769786489008 0.621534326184767 1.0 1.0 37 O43909,O75175,Q13868,Q96L73,P42858 5 +Eyelid coloboma 0.3784843878293984 0.4919743553665452 0.6227374726214479 1.0 1.0 11 O15160,Q15427,Q6NUK1,Q9H9Y6,Q13428 5 +Hypoparathyroidism 0.3833531905143607 0.4918522823712515 0.622823773387799 1.0 1.0 14 Q969N2,P03915,P55084 3 +Asymmetric growth 0.3781432870269176 0.4905310416539671 0.6237581695260543 1.0 1.0 11 P31749 1 +Dysdiadochokinesis 0.385367429293143 0.4895538275966192 0.6244496559705488 1.0 1.0 17 O15020 1 +Severe infection 0.3757128472454841 0.4893785799233854 0.6245736979823482 1.0 1.0 10 Q7L590,O95394,P54132 3 +Elevated circulating glutaric acid concentration 0.4897983600547769 0.4889076459838593 0.6249070823148934 1.0 1.0 4 Q92947 1 +Abnormality of the ovary 0.2852765180660915 0.4861434274951025 0.6268654783347327 1.0 1.0 61 Q15056,Q15031,P54132,Q9UI10,Q8NFV4,O75616,O60934,P31749,O43709,Q86W42 10 +Specific learning disability 0.3052933992234418 0.4852245139980202 0.6275170948039523 1.0 1.0 73 O43909,P54132,Q9H6K4,P42858,P03915,O75962,Q86W42 7 +B lymphocytopenia 0.4201458887772742 0.4851706913576647 0.6275552703247558 1.0 1.0 7 Q7L590,O60934 2 +Submucous cleft soft palate 0.5413148371531927 0.4834180082487971 0.6287989641708442 1.0 1.0 3 Q15233,P18583 2 +Hypopigmentation of the fundus 0.4873955941756823 0.4806990709632783 0.6307303915286706 1.0 1.0 4 Q6P2Q9 1 +Bone marrow hypocellularity 0.3749190027439226 0.4805722246033508 0.6308205600089691 1.0 1.0 27 Q9BUR4,O60832,O76094,Q96AX1,P26440,P11766,O95394,Q5F1R6,P62263,O60934,P61011,Q9H078,P61254,Q9Y3A5,P06748 15 +Neoplasm of the genitourinary tract 0.3061591661586343 0.4795981517030802 0.6315131608665041 1.0 1.0 74 P18077,Q96L73,P62857,P51809,P42771,O60934,P62081,Q9NWH9,Q07812,P61353,P31749,P62847,P62899,Q03426,P36957,P60866,P54132,O60333,P61313,P62244,Q9Y6D9 21 +Overriding aorta 0.3731337490330881 0.4785783960184658 0.6322385905742349 1.0 1.0 10 Q8NFV4,P78347,Q15056,O43709 4 +Abnormal csf carboxylic acid concentration 0.4316038595237619 0.4783907653528092 0.6323721051141924 1.0 1.0 6 P08559 1 +Retinal coloboma 0.3729963192561606 0.4780058733540783 0.6326460247048142 1.0 1.0 10 Q8N201,Q9NP72 2 +Abnormal rib ossification 0.4865158746533608 0.4777062240810074 0.6328593137240539 1.0 1.0 4 P61011,Q9Y3A5 2 +Personality changes 0.3828236064799782 0.4773995350621294 0.6330776452206295 1.0 1.0 20 Q9UI10,P03915,P42858 3 +Opisthotonus 0.379416793432536 0.4770216908180485 0.6333466759789372 1.0 1.0 24 Q96RQ3,Q99720,O43909,Q9H078 4 +Aphasia 0.3120860884318254 0.4745850717419064 0.6350827486578043 1.0 1.0 42 O75175,P46100,O15160,P42858,Q9H9Y6,P03915,P31483 7 +Angioid streaks of the fundus 0.7757009345794249 0.4722443422538251 0.6367523925335927 1.0 1.0 2 P31749 1 +Abnormality of malar bones 0.291490564919853 0.4698453306327707 0.638465525211299 1.0 1.0 66 Q969N2,O75175,P46100,P54132,O15160,Q9Y4W2,Q9BZK7,O60568,Q9H9Y6,Q15125 10 +Enlarged posterior fossa 0.268948081072448 0.4665386148200614 0.6408300141977052 1.0 1.0 53 P62140,Q12824,O60826,O75175,P60953,Q9NPL8,Q15125 7 +Psychogenic non epileptic seizure 0.3669848735595964 0.4654661347137995 0.6415976831625625 1.0 1.0 29 Q9NXH9,O75175,O60333,P51608,P42858,Q9ULV3,Q9BPU6 7 +Aplasia hypoplasia involving the sinuses 0.4459700458477689 0.4650535710451732 0.6418930936342053 1.0 1.0 5 P46100 1 +Weak voice 0.4274547783291477 0.4629774220173631 0.6433805508041037 1.0 1.0 6 O75787 1 +Clonus 0.3571145130013616 0.4614872019627302 0.6444491012603124 1.0 1.0 32 Q969N2,Q99720,Q9NP72,P11498,P42858,O75787 6 +Smooth philtrum 0.3068480961747032 0.4613865545810764 0.6445212961878766 1.0 1.0 76 Q9NXH9,P62140,O75175,P10586,Q96ST3,P60953,P42858,Q9BZK7,Q8WVX9,Q86W42 10 +Medulloblastoma 0.3997416009925449 0.4609903121393202 0.6448055556747703 1.0 1.0 8 O60934,Q12824 2 +Abnormal granulocyte count 0.3149174695033552 0.4609647731734456 0.6448238787985971 1.0 1.0 81 P18077,P62857,Q9H9E3,Q8N5M9,Q9Y3A5,O43909,P62081,Q9H078,O95394,P61353,P62847,P62899,Q03426,P60866,P05165,P22033,P46100,Q9Y3C6,O75083,Q9BZK7,P61313,P62244 22 +Abnormal left ventricle morphology 0.3533103168974741 0.4601281466179623 0.64542424205789 1.0 1.0 33 O75880,Q07021,P03915,Q06124,Q7LG56,P55084,Q969Y2,Q6NUK1,Q15233,P40939,Q13724,P78536,O75787 13 +Abnormal lacrimal duct morphology 0.4134415553919889 0.4596481717633115 0.6457687764084008 1.0 1.0 7 P62140,A6NHR9,P48651 3 +Abnormal femoral head morphology 0.3767769960101356 0.4596210249903066 0.6457882651091063 1.0 1.0 23 Q7RTS9,O43909 2 +Urethral valve 0.5328535132867173 0.456668560305205 0.6479092919765905 1.0 1.0 3 Q96L73 1 +Congenital posterior urethral valve 0.5328535132867173 0.456668560305205 0.6479092919765905 1.0 1.0 3 Q96L73 1 +Esophageal stenosis 0.4123129492863393 0.4554029206060137 0.6488193945039653 1.0 1.0 7 Q9BUR4,O95394,O60832 3 +Peptic ulcer 0.3743381940064245 0.4538209572019834 0.6499576983424769 1.0 1.0 14 Q8NFV4,Q15056,O43709,P53680 4 +Patent ductus arteriosus 0.3233325172748199 0.4528287774273102 0.6506720398947148 1.0 1.0 87 Q969N2,P62140,O60762,Q12824,O60826,Q6ZXV5,Q15031,O15160,Q15056,Q8NFV4,Q96L73,Q9Y3D3,P60953,O43709,Q9H9Y6,Q86W42 16 +Hypokinesia 0.3739692717657513 0.4522951335394774 0.6510563812931083 1.0 1.0 14 Q96RP9,Q9Y281,Q9Y3D3,P42858 4 +Aplasia hypoplasia of the ear 0.2787809990313064 0.4511372750033279 0.6518906139484903 1.0 1.0 60 P18077,P62857,P39019,P08708,P33992,O15160,Q9Y4W2,P62081,O95202,P61353,P62847,P62899,Q9H9Y6,P60866,P46100,Q15427,O95602,P61313,P62244 19 +Unilateral renal agenesis 0.3767203189922907 0.4507853414057046 0.652144267180816 1.0 1.0 20 Q86XL3,Q96C36,Q06124,Q15427,Q9UBM7,P60953,Q86W42 7 +Aplasia hypoplasia of the thumb 0.2685202991123559 0.4507424035584862 0.6521752170344335 1.0 1.0 54 P08708,P60866,P61313,P18077,Q15427,Q9UBM7,P61353,P62857,Q96ST3,P62081,P39019,O60216,P62847,P62899,O95202,O75962,P62244 17 +Neoplasm of the colon 0.3080910139319983 0.4501379278596664 0.6526109902379373 1.0 1.0 42 P60866,P54132,P18077,P42771,P61353,P62857,P62081,P62847,P62899,P61313,P62244 11 +Abnormal c peptide level 0.4782593512719644 0.4499548957573131 0.6527429634971054 1.0 1.0 4 P40939 1 +Stomach cancer 0.3713423693109969 0.4473462334356102 0.6546250901311601 1.0 1.0 13 P42771,P54132 2 +Neonatal onset 0.3729409980348105 0.4426638730655242 0.6580088771477337 1.0 1.0 23 P09001,P11047,O14654,P55809,Q96EY8,P34897,Q9H4L7,P55084,P40939,P51659,Q8TB36,O75787 12 +Abnormality of the pulmonary veins 0.3946314395952822 0.4413998346250539 0.6589235619247171 1.0 1.0 8 P57076 1 +Erythroderma 0.3662382227532117 0.4413567331173139 0.6589547600882333 1.0 1.0 11 O43909,P78536 2 +Abnormal tracheal morphology 0.3123402069645552 0.4407785121536551 0.6593733511252406 1.0 1.0 41 O43909,Q15056,O15160,Q8NFV4,O43709,Q9H9Y6,Q15125 7 +Bronchiectasis 0.374184874549117 0.440144079275049 0.659832758366522 1.0 1.0 18 P54132,Q03518,O95394,Q86TI2,P57076,O60934 6 +Renal tubular atrophy 0.4751643423974628 0.4397144817120285 0.6601439125716582 1.0 1.0 4 Q9NQH7 1 +Anterior pituitary dysgenesis 0.7633403678022301 0.4395584642298905 0.6602569293850036 1.0 1.0 2 Q9NW13 1 +Elliptocytosis 0.526515233656286 0.4370185384147758 0.6620979036051082 1.0 1.0 3 Q8NBF2 1 +Increased circulating prolactin concentration 0.4072725790191566 0.4366305449305168 0.6623793070392872 1.0 1.0 7 P31749 1 +Microphallus 0.4741409186889946 0.4363483837051192 0.6625839825288731 1.0 1.0 4 Q8NI27 1 +Renal tubular acidosis 0.3679493227516701 0.4335734057013256 0.6645982502547019 1.0 1.0 13 P11498,Q9BRT2 2 +Arnold chiari malformation 0.3715842830473013 0.430425580169055 0.6668860909338215 1.0 1.0 21 P62140,Q15056,Q14839,Q8NFV4,Q9BZK7,O43709,P78347 7 +Abnormal brainstem morphology 0.3305285594013025 0.4281384967914603 0.668550290566654 1.0 1.0 94 Q5T160,O60762,Q12824,Q96S52,Q6ZXV5,O43676,Q9Y3C6,Q86Y39,O43819,Q8IUX1,Q969Y2,O75380,P31749,P28331,Q9NPL8,Q96CU9,Q9UGM6,Q99986 18 +Spastic paraplegia 0.2635778082631113 0.4275335118739622 0.6689907817101308 1.0 1.0 53 P46100,P19404,Q9BSH4,Q8TD30,Q5MNZ6,Q04446,Q96KR1,Q9P0J0,P08559,P28331,Q96CU9,Q8TAF3 12 +Left ventricular hypertrophy 0.3612277719414868 0.427036361519626 0.6693528435170271 1.0 1.0 28 O75880,Q07021,P03915,Q7LG56,P55084,Q969Y2,Q6NUK1,Q15233,P40939,Q13724,P78536,O75787 12 +Abnormality of the antihelix 0.3643881261895698 0.4261342546887557 0.6700100209568756 1.0 1.0 12 O94761,Q15042,Q9H2M9,P27635,Q5SRE5,O75962,Q15029 7 +Limb hypertonia 0.3300863685314493 0.4254710614819538 0.6704933129643158 1.0 1.0 37 Q9BW92,P46100,Q8TCS8,P05165,Q8WVX9,Q9H9E3,P17480,Q9UGM6,Q8TAF3,Q15125 10 +Cafe au lait spot 0.261429701444539 0.4244063665133827 0.6712694784684428 1.0 1.0 52 Q9NXH9,P62140,O75175,P54132,O60333,P31749,O60934,P42858 8 +Abnormality of the tarsal bones 0.3625581624160061 0.4234255089183044 0.6719848367708032 1.0 1.0 27 O75787,P55084,Q7RTS9,Q5SRE5,Q15125 5 +Right bundle branch block 0.3617157543219831 0.4233185784591558 0.6720628411845786 1.0 1.0 11 P62140,Q99996,Q9HD47 3 +Short palm 0.3659255429757288 0.4229245091900627 0.6723503401970488 1.0 1.0 25 O60762,P48651,Q96ST3,Q9BZK7,Q9H9E3,O75962 6 +Acute pancreatitis 0.5216799936230485 0.4222616744863033 0.6728340290408108 1.0 1.0 3 P35914 1 +Ophthalmoparesis 0.3105898927355241 0.421662071233531 0.6732716927880105 1.0 1.0 82 Q12824,P50213,Q9H0U9,P30038,O75695,Q07021,P11047,P19404,O94906,P08559,P28331,Q96CU9,Q96IX5,Q9BQP7,Q9BSH4,Q92620,P31749,P03915,Q5ST30,O43819,Q7LG56,Q99700,P22570,Q9P2R7,Q9P0J0 25 +Postnatal growth retardation 0.2909984561481115 0.4205925798848389 0.6740526129625797 1.0 1.0 70 O95235,P26373,Q12824,O60826,P46100,P54132,Q9NP72,Q96ST3,P60953,O60568,Q7RTS9,Q9H9E3,Q15125 13 +Abnormality of the diencephalon 0.3453030829227778 0.4203614436040794 0.6742214300293283 1.0 1.0 33 Q12824,Q15056,O43819,Q969Y2,Q8NFV4,P31749,O43709 7 +Urinary tract neoplasm 0.3087480812609748 0.4201755421371877 0.6743572204440129 1.0 1.0 41 P36957,P60866,P54132,Q9NWH9,P42771,Q07812,O60333,P31749,Q96L73,Q03426 10 +Aortic aneurysm 0.2675618519429941 0.4197789246134211 0.6746469623663471 1.0 1.0 56 Q9NXH9,P62140,Q6ZXV5,O75175,O95394,Q8NFV4,Q96L73,P42858,O43709 9 +Abnormal motor evoked potentials 0.5208082026537972 0.4196230890315668 0.6747608185002285 1.0 1.0 3 Q9UNE7,Q9NZJ4 2 +Abnormality of the thymus 0.3677852201979309 0.4184519855477002 0.67561668474115 1.0 1.0 16 Q7L590,P31749,O15160 3 +Nuclear cataract 0.4142478256815786 0.4151503290039032 0.6780318579223914 1.0 1.0 6 Q03426,Q99797 2 +Dilated fourth ventricle 0.2834062405259915 0.4146495248385763 0.6783984877889395 1.0 1.0 45 P62140,Q12824,O60826,Q99700,P60953,Q8WVX9,Q9UGM6,Q9BPU6,Q15125 9 +Scleral staphyloma 0.4674595982233246 0.4146250844853218 0.6784163820882576 1.0 1.0 4 Q969N2 1 +Periventricular leukomalacia 0.3658534391054436 0.4145527368687449 0.678469353330883 1.0 1.0 15 P11498,Q9NXH9,P08559,Q9Y6X9 4 +Difficulty climbing stairs 0.3656445557140498 0.4137222905150131 0.6790775005657421 1.0 1.0 15 O75340,O95140,Q7LG56,P40939,P55084 5 +Skeletal muscle hypertrophy 0.26941334505567 0.41290912496809 0.679673195333323 1.0 1.0 47 Q12824,Q96S52,Q15056,P46100,Q8NFV4,P31749,O43709,Q9ULV3 8 +Severe varicella zoster infection 0.4666715386986131 0.4120922285146907 0.6802718246483863 1.0 1.0 4 P54132 1 +Transient neutropenia 0.4308431711948834 0.412021613490091 0.6803235814641471 1.0 1.0 5 Q9H078,Q9Y3A5 2 +Glutaric aciduria 0.4307552155316541 0.41172059346805 0.6805442289899042 1.0 1.0 5 Q92947,P38117 2 +Prominent occiput 0.3621392856753197 0.4104877105114456 0.6814482167818232 1.0 1.0 13 O75175,O60826 2 +Abnormality of pulmonary circulation 0.3517781285443747 0.4067620527609647 0.6841827600648536 1.0 1.0 30 O95235,P11047,P31749,Q9NP81,P03915,Q9UMS0 6 +Abnormal salivary gland morphology 0.4290486904701832 0.4058977030855765 0.6848177658061934 1.0 1.0 5 Q02218,Q13428 2 +Abnormal dental root morphology 0.3849832642913606 0.4054010838074316 0.6851827144406475 1.0 1.0 8 Q9BUR4,O60832 2 +Abnormal morphology of myocardial trabeculae 0.4288374073678972 0.4051791085280562 0.6853458602988243 1.0 1.0 5 Q15233,P14923,Q99797 3 +Tracheal stenosis 0.3984434001251879 0.4045152001048154 0.6858339026786462 1.0 1.0 7 O43909 1 +Abnormal optical coherence tomography 0.7485679831172719 0.4018362358313136 0.6878045524506344 1.0 1.0 2 P04439 1 +Photoreceptor layer loss on macular oct 0.7485679831172719 0.4018362358313136 0.6878045524506344 1.0 1.0 2 P04439 1 +Abnormal pupil morphology 0.3578686677090835 0.4006123154592886 0.6887055770330575 1.0 1.0 12 P61586,P11047,Q96ST3,Q96IJ6 4 +Abnormality of the zygomatic bone 0.2975793726215581 0.4000915547714637 0.6890890842371429 1.0 1.0 76 Q969N2,O75175,Q9H9Y6,P46100,P54132,O15160,Q9Y4W2,Q8NFV4,O60934,Q9BZK7,O60568,O43709,Q9H9E3,Q15125 14 +Choanal stenosis 0.4268330171111159 0.398387784735496 0.6903443607190289 1.0 1.0 5 Q9H9Y6 1 +Neoplasm of the respiratory system 0.3635045583691799 0.3966628106356729 0.6916161278787039 1.0 1.0 18 P31749,Q96L73 2 +Abnormal circulating gonadotropin concentration 0.3600361428338744 0.396544186868294 0.6917036173401261 1.0 1.0 14 P31749,Q12824 2 +Loss of purkinje cells in the cerebellar vermis 0.7452517334941238 0.3935783617872124 0.6938923592318909 1.0 1.0 2 O00567 1 +Progressive microcephaly 0.286280765657238 0.3932288644277824 0.6941504526094633 1.0 1.0 44 Q5T160,O43909,P00505,P51608,Q9Y3E5,P60953,P28331,Q99798,Q8WVX9 9 +Duplication of hand bones 0.2785212712954651 0.392736754285872 0.6945139214060485 1.0 1.0 65 O43909,O60826,P54132,P61353,P62847,P62857,Q15125 7 +Abnormal erythrocyte enzyme level 0.3611721264011815 0.3896134241050959 0.696822424091164 1.0 1.0 22 P60866,P18077,P61353,P62847,P62857,P62081,P62899,P61313,P62244 9 +Poor appetite 0.3594406518442564 0.3894598546935687 0.6969360023275681 1.0 1.0 15 P05165,P46100,P54132,P42771,Q7LG56 5 +Down sloping shoulders 0.3546454509621419 0.3889075191234407 0.6973445597379682 1.0 1.0 27 Q9NXH9,O75175,Q15056,Q8NFV4,P42858,O43709,Q9BPU6 7 +Abnormal circulating sex hormone concentration 0.3615073816411652 0.3888981790749891 0.6973514692386442 1.0 1.0 21 Q9UI10,P31749,Q12824 3 +Patchy palmoplantar hyperkeratosis 0.7425384383479059 0.3868810613616089 0.6988442623589082 1.0 1.0 2 Q06136 1 +2 3 finger syndactyly 0.7425384383479043 0.3868810613616056 0.6988442623589106 1.0 1.0 2 P14923 1 +Hypovolemic shock 0.7425384383479043 0.3868810613616056 0.6988442623589106 1.0 1.0 2 P14923 1 +Vitreous hemorrhage 0.5085693929705228 0.3833200107970343 0.7014825038401757 1.0 1.0 3 P29992 1 +Cough 0.3464793546530813 0.383120715168425 0.7016302608377241 1.0 1.0 30 Q9BZK7,P41440,P57076 3 +Squamous cell carcinoma 0.3594600550045879 0.3827920364470388 0.701873966597131 1.0 1.0 17 P42771,P54132,O60832 3 +Insulin resistance 0.3599479585898039 0.3827250998732531 0.7019236018883659 1.0 1.0 18 P54132,O95140,P43304,Q96MF7,P17096,P28340,Q9Y6M1,Q9UKG1 8 +Decreased activity of mitochondrial complex ii 0.4217836121477979 0.381489937225534 0.7028397366322365 1.0 1.0 5 P31040,Q5T440,Q9H1K1 3 +Abnormality of periauricular region 0.3577584706094621 0.3788940491654083 0.7047665434017147 1.0 1.0 23 Q9H9Y6,O60826,Q96S52,O15160 4 +Cutaneous syndactyly of toes 0.4559626553105494 0.3783148417427663 0.7051967212090489 1.0 1.0 4 P51608,Q9H4L7 2 +Broad philtrum 0.3499846897927108 0.3783064112886035 0.7052029832103297 1.0 1.0 11 Q9BZK7 1 +Abnormal nasolacrimal system morphology 0.3537005309155738 0.3781287259663549 0.7053349695612181 1.0 1.0 13 P62140,P53701,P48651,Q6NUK1,Q9Y617,A6NHR9 6 +Limb dystonia 0.3562887251844533 0.3774381189789916 0.7058480431977623 1.0 1.0 15 Q9UGM6,Q99720,P10515,Q8TCS8 4 +Scaling skin 0.3466776115088228 0.3744037654585857 0.7081039419070247 1.0 1.0 10 P78536 1 +Aplasia hypoplasia of the retina 0.5054282267792464 0.3742326298750871 0.7082312496996122 1.0 1.0 3 Q9Y6K9,Q86YV9 2 +Rod cone dystrophy 0.2827742810431316 0.3730760345852514 0.7090918547533203 1.0 1.0 44 O75695,Q13868,Q6P2Q9,Q9NQ48,O94906,Q92620,P57076,Q99700,P22570,Q03426,P03915,Q9UGM6,Q16795 13 +Postural tremor 0.3570956299280383 0.3706971169616284 0.7108631379181098 1.0 1.0 19 P03915,Q9H6K4 2 +Hyperacusis 0.3604914433195755 0.3691546841195841 0.7120124308521434 1.0 1.0 9 Q8NFV4,Q15056,O43709 3 +Spondyloepimetaphyseal dysplasia 0.3740372185551588 0.3662360096022388 0.7141889741761192 1.0 1.0 8 Q7RTS9 1 +Arm dystonia 0.4513137403936926 0.3640370155830904 0.7158303685820269 1.0 1.0 4 Q99720 1 +Abnormality of subcutaneous fat tissue 0.3543715479252091 0.3634637601000456 0.716258479771221 1.0 1.0 17 P31749 1 +Facial diplegia 0.3451387572436338 0.3605015640111574 0.718472087234425 1.0 1.0 11 Q9Y281,Q7LG56,O43819 3 +Neoplasm of the ear 0.4500894737164013 0.3603172497048482 0.7186099010570162 1.0 1.0 4 Q96L73 1 +Shuffling gait 0.344932616503977 0.3597547951828627 0.7190305110189996 1.0 1.0 11 P51608,Q99700,O60220 3 +Short palpebral fissure 0.3409241146650775 0.3592566295582468 0.719403116087457 1.0 1.0 30 Q13868,Q86W42 2 +Aplasia hypoplasia involving the metacarpal bones 0.3403094645319066 0.3566756239430829 0.7213346561174225 1.0 1.0 30 Q7RTS9,O43909,O75962 3 +Abnormal head movements 0.3457143491701977 0.3552656276644785 0.7223906032254097 1.0 1.0 12 Q969N2,Q99720 2 +Increased laxity of ankles 0.7283690081398695 0.3527954904844421 0.7242417647518111 1.0 1.0 2 O95140 1 +Full cheeks 0.3228796796451841 0.3500133006899396 0.7263287157609819 1.0 1.0 35 P10412,O43909,Q9BZK7,Q8N201 4 +Neurofibromas 0.395154528700417 0.349682466959283 0.7265770133040159 1.0 1.0 6 P31749 1 +Localized hirsutism 0.4465456511166243 0.3496461995097942 0.7266042345209895 1.0 1.0 4 P12955 1 +Abnormality of urine catecholamine concentration 0.3544744784737238 0.3479443562426849 0.7278819726228787 1.0 1.0 9 O60333,P11388,P31040,P36957 4 +Chronic mucocutaneous candidiasis 0.3686126106498919 0.34753064597776 0.7281926993521488 1.0 1.0 8 O95394,Q03426 2 +Abnormality of the spinocerebellar tracts 0.4958073931882764 0.3470130613695467 0.7285815062342356 1.0 1.0 3 Q7LG56 1 +Abnormal renal echogenicity 0.7253542357551916 0.3457409151116748 0.7295374325159649 1.0 1.0 2 Q9NP81 1 +Abnormality of the incisor 0.3319463604891237 0.3450096811101227 0.7300870926227601 1.0 1.0 32 P54132,O75175,P42858,P46100 4 +Elevated circulating follicle stimulating hormone level 0.444792766256522 0.3444216134313863 0.7305292368952157 1.0 1.0 4 P51809 1 +Neoplasm of the male external genitalia 0.3403166016452491 0.3432647038658477 0.7313993316337233 1.0 1.0 11 P31749,P42771 2 +Decreased circulating androgen concentration 0.3526974927971792 0.3418076832681669 0.7324956270707037 1.0 1.0 9 P31749,Q12824,Q9NW13 3 +Short femur 0.4093139203683879 0.3411131768374827 0.733018381827877 1.0 1.0 5 O00116 1 +Hypogonadotropic hypogonadism 0.3388605280128023 0.3408397960965523 0.7332241894051652 1.0 1.0 29 Q12824,Q15056,Q9Y4W2,Q7LG56,Q8NFV4,P31749,O43709,P03915,P78347 9 +Frequent falls 0.2827207575983539 0.3405975870168594 0.7334065462312696 1.0 1.0 43 O75340,P11047,O95140,Q99653,Q9UHD1,O43819,P37198,Q9NXN4,P55084,Q7LG56,Q7RTS9,O75787 12 +Small for gestational age 0.2997689719330187 0.338705600783068 0.7348315209999665 1.0 1.0 84 P18077,Q6NUK1,P62857,Q9Y3D3,P40939,P39019,Q96ST3,Q15046,Q9Y3A5,P08708,P46777,Q96EY7,P51608,P62854,P35270,P62081,P08559,Q5SRE5,O95202,Q9NXH9,P61353,P62847,P62899,P55084,P60866,P54132,P47985,Q9BZK7,P61011,P61313,Q8NI27,P62244 32 +Abnormality of the hallux 0.2647707758995877 0.3384532351838137 0.7350216626765822 1.0 1.0 62 O60762,Q9NXH9,O75175,O60826,Q15056,O95140,Q15427,P61586,Q8NFV4,P31749,Q9Y3E5,P42858,O43709,P78347,Q9BPU6,Q15125 16 +Abnormal upper motor neuron morphology 0.340738562853903 0.3375867951000273 0.7356745945620673 1.0 1.0 12 Q99720,Q04446 2 +Neonatal respiratory distress 0.3470321714638197 0.3372954732190854 0.7358941718238889 1.0 1.0 23 P11047,P57076,Q96EY7,Q01970,P08559,Q8N9N2,Q9Y3A5 7 +Macroorchidism 0.4078511607676979 0.3365084797077526 0.736487458168601 1.0 1.0 5 P31749 1 +Impaired tandem gait 0.3474295825593864 0.3347308796354897 0.7378281052934588 1.0 1.0 19 O75175,P42858,O75787 3 +Elevated calcitonin 0.3647576792523598 0.3345348026604382 0.7379760333999414 1.0 1.0 8 O60333,P36957,P31040 3 +Hypertension associated with pheochromocytoma 0.3647576792523598 0.3345348026604382 0.7379760333999414 1.0 1.0 8 O60333,P36957,P31040 3 +Peripheral visual field loss 0.7196261682242892 0.3325338209803835 0.7394862058213449 1.0 1.0 2 P10515 1 +Pes planus 0.2924038362059696 0.3325052502046516 0.7395077759277715 1.0 1.0 80 O75340,Q9NXH9,O75175,P46100,Q9Y4W2,O43819,Q9Y2D4,Q8NFV4,Q96L73,Q9BZK7,O43709,Q7RTS9,O75962,O75787 14 +Interrupted aortic arch 0.4404223227752659 0.3315528073360908 0.7402269598303011 1.0 1.0 4 Q96DF8,Q8WYQ5,P53597 3 +Abnormal protein glycosylation 0.3451156593340435 0.3298184680629897 0.7415371320037454 1.0 1.0 17 O75340,Q9H9E3,Q8N511,O75787 4 +Abnormal cerebellar vermis morphology 0.2964854661718993 0.329365277416626 0.7418796095606566 1.0 1.0 83 Q12824,P00505,Q96L73,Q9UGM6,Q96S52,Q9NP72,Q99653,Q8N201,P60953,P42858,Q96B26,Q9BPU6,O60826,Q9UHD1,Q03426,Q15125,P62140,P22570,Q8NI27,Q8WVX9 20 +Cerebral hypoplasia 0.3448145847132663 0.3287577807049333 0.7423387768695504 1.0 1.0 17 O60762,Q5MNZ6,Q86XL3,P22570 4 +Prostate neoplasm 0.3334535149656131 0.3273734424703403 0.7433854506102302 1.0 1.0 10 O60934,Q9Y6D9 2 +Distal upper limb amyotrophy 0.339367498450962 0.3265665917400775 0.7439957151955501 1.0 1.0 13 O60568 1 +Reduced systolic function 0.4385534425817139 0.3261195868826333 0.7443338782521947 1.0 1.0 4 P14923,Q3LXA3 2 +Abnormality of exocrine pancreas physiology 0.3449072464369559 0.3257183820291357 0.7446374351917415 1.0 1.0 19 P42771,Q9Y3E5,P14174,Q9Y3A5,Q9UKG1 5 +Pulmonary fibrosis 0.3447062204920507 0.325006889796979 0.7451758572276403 1.0 1.0 19 Q8NI27,Q86TI2,P14174 3 +Ventricular fibrillation 0.3874671493318971 0.3246798923851366 0.7454233544316498 1.0 1.0 6 Q9HD47 1 +Postaxial polydactyly 0.343739960757796 0.3229090011108431 0.7467641592885941 1.0 1.0 22 O43909,Q9BRT2 2 +Sound sensitivity 0.331503076172466 0.3207488514579106 0.7484007234934653 1.0 1.0 10 Q8NFV4,Q15056,O43709 3 +Dental malocclusion 0.3400397649797459 0.3187436985166213 0.7499208749837702 1.0 1.0 25 Q15056,Q06124,Q06210,P61586,Q8NFV4,P60953,O43709,A6NHR9,P78347,Q86W42 10 +Secondary microcephaly 0.2881517094788925 0.3181315898199799 0.7503851222178304 1.0 1.0 79 Q5T160,O60762,O43909,P00505,Q9NP72,Q86Y39,Q8TD30,Q05086,Q9UI10,Q9Y3E5,P60953,P28331,Q99798,Q8WVX9,Q96CU9,O75962 16 +Progressive leukoencephalopathy 0.4850289569467814 0.3176644140099072 0.7507395075121044 1.0 1.0 3 Q5JTZ9 1 +Cleft lip 0.2560523735195695 0.3164821702517749 0.7516365563088694 1.0 1.0 59 P18077,P62857,P39019,A6NHR9,P08708,O15160,Q8N201,O60934,P62081,O95202,P14923,P61353,P62847,P62899,Q9H9Y6,P60866,Q15427,P61313,Q15738,P62244 20 +Upper eyelid coloboma 0.7123907145010574 0.3162263098615139 0.7518307392261616 1.0 1.0 2 Q6NUK1 1 +Pointed chin 0.3302180542574721 0.3160456524799911 0.7519678569677661 1.0 1.0 30 Q8NFV4,Q96L73,O43709,Q86W42 4 +Microretrognathia 0.3389904731490479 0.3153382400221655 0.7525048535948522 1.0 1.0 15 Q15427,Q96ST3,Q8N201,Q15125 4 +Absent hair 0.3342174613837267 0.3152346526358353 0.7525834968166683 1.0 1.0 12 O15160,P62304,P15924,Q9H9Y6,P14923 5 +Gliosis 0.271865450005641 0.3149667976126256 0.7527868634218478 1.0 1.0 44 Q13148,O43819,Q9NXN4,Q9UI10,P08559,P42858,Q99986 7 +Premature graying of hair 0.344629177972412 0.3146993580188489 0.7529899317337778 1.0 1.0 9 Q9BUR4,O60832,P06748 3 +Poor head control 0.2872572378564623 0.3134671389318804 0.7539257828551467 1.0 1.0 79 Q5T160,O75340,P11047,Q8TCS8,O43676,Q86Y39,Q8IUX1,O75380,P28331,Q9NPL8,Q96CU9,Q9UGM6,Q9P0J0 13 +Abnormal vena cava morphology 0.3441128338929449 0.3130075086866882 0.7542749574889189 1.0 1.0 9 P47985,P57076,P11766 3 +Abnormal endocrine physiology 0.4001954317325149 0.3128806841002365 0.7543713131901966 1.0 1.0 5 Q13724 1 +Abnormal tricuspid valve physiology 0.3407369857904555 0.3122154008421215 0.7548768285348035 1.0 1.0 22 O95235,P62140,P46100,P53701,Q96AX1,Q15233,O60216,P40939,P39019,P55084 10 +Abnormal platelet volume 0.3577506514842651 0.3115662889320261 0.7553701573000666 1.0 1.0 8 P60953 1 +Supravalvular aortic stenosis 0.32841321917047 0.3104242467667608 0.7562383579763274 1.0 1.0 10 Q8NFV4,P78347,Q15056,O43709 4 +Abnormality of neutrophils 0.3137413571361329 0.3089996907890583 0.7573217620341401 1.0 1.0 97 Q96AX1,Q96EY8,P18077,P40123,P62857,P39019,Q14126,Q8N5M9,Q9H9E3,P41440,Q9Y3A5,P06748,P08708,P31040,P62854,P62081,Q9H078,O60832,Q9BUR4,O95394,P61353,P62847,P62899,P15924,Q03426,Q9Y2Q5,P05165,P22033,P46100,Q9Y3C6,P60866,O75083,Q9BZK7,P61011,P61313,P62244 36 +High pitched voice 0.3338999588955234 0.3080917467996054 0.75801252109218 1.0 1.0 13 Q9Y6X9,P54132,O75431,P28340,Q6ZRS2,P50454,P08069 7 +Disproportionate short stature 0.3370538286863278 0.3079201033044348 0.7581431283051252 1.0 1.0 25 Q7RTS9,O43909 2 +Thin eyebrow 0.3366278586349648 0.3073886384994002 0.7585475750245123 1.0 1.0 15 P62857 1 +Enlarged cisterna magna 0.3387545479756716 0.3057385439745771 0.7598037237849533 1.0 1.0 18 Q96L73,O75175,Q9NPL8 3 +Decreased fertility 0.3355540426803436 0.3025816701424034 0.7622086851270906 1.0 1.0 25 P54132,P57076 2 +Ocular anterior segment dysgenesis 0.3108708293608459 0.3023582219454276 0.7623789991995586 1.0 1.0 96 P18077,P38117,Q8NFV4,P62857,P39019,P11047,Q8TCS8,Q99797,Q9NP72,Q15056,P62081,O43709,Q5SRE5,O95202,P61353,P31749,P62847,P62899,P03915,P78347,Q9UBC2,P36957,P60866,O60333,P61313,Q8WVX9,P62244 27 +Neoplasm of the eye 0.3360376331963899 0.3017198574330616 0.7628656293049811 1.0 1.0 16 P36957,P31040,O60333,Q02978,P31749 5 +Cerebral white matter hypoplasia 0.3676131877079394 0.3009809475009449 0.7634290229803786 1.0 1.0 7 Q9UGM6,P22570 2 +Alopecia totalis 0.3675415251963371 0.3007573542651904 0.7635995299224341 1.0 1.0 7 P47985,P14923,P15924 3 +Tremor by anatomical site 0.3280325388334107 0.2992519108231009 0.7647478437992143 1.0 1.0 29 Q99720,O95140,Q15120,Q96KR1,Q9ULV3 5 +Demyelinating peripheral neuropathy 0.3364889193172828 0.2967964843931374 0.7666218896531451 1.0 1.0 19 P03915,P41440 2 +Cleft soft palate 0.2549172962187671 0.2929523829698923 0.7695585485190335 1.0 1.0 61 P18077,Q15058,Q15233,P62857,P39019,A6NHR9,P08708,P34897,P46777,P48651,P62854,P62266,P62081,P61353,Q9Y617,P62847,P62899,P62140,P60866,P61313,P62244 21 +Absent facial hair 0.3252242726983257 0.2925722425126426 0.7698491330634769 1.0 1.0 11 O15160 1 +Abnormal soft palate morphology 0.2736565381376254 0.2918402566847123 0.7704087640051847 1.0 1.0 73 Q96DF8,P18077,Q15058,Q15233,P62857,P39019,A6NHR9,Q86W42,P08708,P34897,P46777,P48651,P62854,P62266,P62081,P61353,Q9Y617,P62847,P62899,P62140,P60866,Q15427,P61313,P62244 24 +Abnormal choroid plexus morphology 0.3504972456013216 0.2887106427465795 0.7728028176377155 1.0 1.0 8 Q12824 1 +Chronic hemolytic anemia 0.6988242387699755 0.2868112300362575 0.7742568637166831 1.0 1.0 2 Q8NBF2 1 +Abnormal prostate morphology 0.3229647613410999 0.2854244649223593 0.7753189664365137 1.0 1.0 11 O60934,Q9Y6D9 2 +Blindness 0.2921405430284425 0.2847702017197899 0.7758202029673666 1.0 1.0 86 O75695,P11047,P46100,Q12824,O43676,Q86Y39,Q9H6K4,Q8IUX1,Q9UI10,P31749,O75380,P08559,P28331,Q9NPL8,Q96CU9 15 +Prolonged bleeding time 0.3623188405797075 0.2846911148300584 0.7758807984284894 1.0 1.0 7 Q15149,O00203,P04637,Q86YV9,P27797,Q14692 6 +Curly hair 0.3223106082507 0.2833771796165062 0.7768877197679296 1.0 1.0 11 P62140,Q9BPU6 2 +Abnormal megakaryocyte morphology 0.3901629450814657 0.2831631224975744 0.7770517959010852 1.0 1.0 5 P62263,P22314,O75533,P27797 4 +Abnormal blood phosphate concentration 0.3484123770515763 0.2823196215496886 0.7776984414484174 1.0 1.0 8 P16930,P53680 2 +Abnormally lax or hyperextensible skin 0.2466457895830071 0.2813049502669158 0.7784765137910967 1.0 1.0 47 Q15022,Q15056,P48651,Q9Y2D4,Q8NFV4,Q96L73,Q9Y3D3,Q9BZK7,O43709,O60832,O75787 11 +Tapered finger 0.2902570841039869 0.2812422607406734 0.7785245927970295 1.0 1.0 39 O75175,P46100,Q9Y4W2,P60953,O75962 5 +Excessive daytime somnolence 0.3312465106913596 0.2811081440770761 0.7786274548649612 1.0 1.0 18 P31749,P42858 2 +Abnormality of the menstrual cycle 0.2364503495481119 0.2807103875251412 0.7789325408860057 1.0 1.0 51 Q12824,Q9UI10,O75616,P31749,Q9BZK7 5 +Broad based gait 0.329097899949887 0.2803610692089257 0.7792005020561741 1.0 1.0 25 P10515,Q8TD30,Q3LXA3,P42858,Q05086 5 +Abnormality of the skull base 0.2492504270795882 0.2802967398647375 0.7792498517909103 1.0 1.0 59 P62140,Q12824,O60826,O75175,P60953,Q9NPL8,Q15125 7 +Tracheoesophageal fistula 0.3300398664634353 0.280208219462421 0.7793177609543895 1.0 1.0 24 Q15056,O15160,Q8NFV4,O43709,Q9H9Y6 5 +Broad finger 0.2984024232911014 0.2799219512300646 0.779537385541132 1.0 1.0 37 O43909,O75175,Q13868,Q96L73,P42858 5 +Hammertoe 0.3308821728439375 0.2788510491567204 0.7803591360456805 1.0 1.0 22 Q99720,Q9Y6X9,O95140,Q99653,Q9UHD1,P51149,O60333,Q9UBM7,Q9NZJ4,Q8TB36 10 +Abnormal iris pigmentation 0.331012537361674 0.2783047941269965 0.7807783962587644 1.0 1.0 20 Q15056,P31749,Q8NFV4,O43709,Q05086 5 +Abnormality of the musculature of the upper limbs 0.2754218734800175 0.2779091332903845 0.7810821126282479 1.0 1.0 76 P18077,P62857,P39019,Q8TB36,A6NHR9,P31483,P08708,O75340,P11047,O95140,Q06124,Q06210,P62081,O60568,Q15120,P61353,P62847,P62899,P60866,Q9Y6X9,Q7LG56,Q96IJ6,P61313,P62244 24 +Abnormal patella morphology 0.3217099897798005 0.2767459686999367 0.781975171920047 1.0 1.0 29 Q6ZXV5,Q15056,Q9Y2D4,Q8NFV4,O43709,P78347,Q15125 7 +Large earlobe 0.3592995169082097 0.2756121069531558 0.7828460097122645 1.0 1.0 7 Q15392,Q96T58,Q8IWS0,Q96N67,O60701,Q15029 6 +Abnormal bronchus morphology 0.3289794978679768 0.2743095854575417 0.7838467188099518 1.0 1.0 23 P54132,Q03518,Q86TI2,P57076,O60934 5 +Carious teeth 0.2513368375117875 0.2736417369789961 0.7843599562673425 1.0 1.0 46 P62140,O60832,Q15056,Q8NFV4,P31749,O43709,P78347,Q9Y3A5,Q86W42 9 +Hand apraxia 0.6921917395236581 0.2729969598361785 0.7848555525456706 1.0 1.0 2 P51608 1 +Abnormal 3rd finger morphology 0.6921917395236563 0.2729969598361756 0.7848555525456729 1.0 1.0 2 Q9Y3E5 1 +Abnormal circulating glutamine family amino acid concentration 0.3584048611304798 0.2729518025405052 0.7848902651547551 1.0 1.0 7 P30038 1 +Aqueductal stenosis 0.3865866254276159 0.2729246058435928 0.7849111715801014 1.0 1.0 5 Q9NPF4 1 +Abnormal sensory nerve conduction velocity 0.3583409834318296 0.2727623851690134 0.7850358757706144 1.0 1.0 7 O95140,Q7LG56,Q9NZJ4,Q9Y3E5,O15269 5 +Spastic paraparesis 0.3288280894816335 0.2722369782411304 0.7854398106444254 1.0 1.0 22 Q8WVX9,Q9H6K4,O75787 3 +Nephrocalcinosis 0.3287301438028118 0.2719245684625473 0.7856800198873282 1.0 1.0 22 Q969N2,Q15056,Q8NFV4,P61011,Q9H078,O43709,Q6ZRS2,P16930,P78347,Q9Y3A5 10 +Urethral obstruction 0.328493222879014 0.27102219498025 0.7863739617682952 1.0 1.0 19 Q9BUR4,Q15056,Q8NFV4,Q96L73,O43709,P78347,O60832,P06748 8 +Periventricular heterotopia 0.3155068558395326 0.2696198235312298 0.7874527479930293 1.0 1.0 10 Q6NUK1,Q6ZXV5,Q9UBM7 3 +Abnormal platelet aggregation 0.4172189847788481 0.2672037900299356 0.7893122581918086 1.0 1.0 4 Q8N5K1,P27797 2 +Hyperactive patellar reflex 0.3146017002961865 0.266902269848116 0.7895444089395511 1.0 1.0 10 Q15233,O95394,Q5T440,Q9NZJ4 4 +Abnormal calcium phosphate regulating hormone level 0.3145462752730941 0.2667364923779133 0.7896720546709575 1.0 1.0 10 O60333,P36957,P31040 3 +Nevus 0.3086007988700289 0.2660997553545313 0.7901623834077132 1.0 1.0 33 Q15022,P10412,Q15056,P42771,Q8NFV4,P31749,P60953,O43709,P78347 9 +Delusions 0.3270882661982985 0.2659738699884861 0.7902593331335148 1.0 1.0 21 Q9UI10 1 +Cerebellar malformation 0.2476493811347395 0.2646515339861061 0.7912779167347364 1.0 1.0 60 P62140,Q12824,O60826,Q8NFV4,P08559,P60953,Q9BZK7,O43709,Q8WVX9,Q15125 10 +Abnormal waist to hip ratio 0.3832464646767098 0.2635355348511072 0.7921378383752979 1.0 1.0 5 P17096,Q9Y6M1 2 +Abnormal qrs complex 0.6870666264696972 0.2625828335442643 0.7928721327292416 1.0 1.0 2 P14923 1 +Short thumb 0.2362936116585755 0.2624639323187955 0.7929637887343088 1.0 1.0 48 P08708,P60866,P18077,Q9UBM7,P61353,P62857,Q96ST3,P62081,P39019,O60216,P62847,P62899,O95202,P61313,P62244 15 +Vestibular dysfunction 0.3095454977063948 0.2595364708986905 0.7952213460611466 1.0 1.0 32 O60333,O60220,Q9BZK7,Q92947,Q03426,P41440 6 +Prominent digit pad 0.3232886140872774 0.2585077782253126 0.7960150467322324 1.0 1.0 24 Q9BZK7,O75175,P42858 3 +Neoplasm of the stomach 0.3239770958093806 0.2584931024561391 0.7960263715342206 1.0 1.0 23 P31749,P60866,P42771,P54132 4 +Abnormal pupillary function 0.3398918861184704 0.2570534108587938 0.797137542032796 1.0 1.0 8 P11047 1 +Neuropathic arthropathy 0.4129437277272641 0.2561159183652037 0.7978613307473468 1.0 1.0 4 O15269 1 +Retinal perforation 0.6837503768465407 0.255966774277892 0.797976493103872 1.0 1.0 2 P04439 1 +Increased proteinogenic amino acid level in urine 0.3130207116972113 0.2553901535722695 0.7984217750152791 1.0 1.0 11 P05165,P30038 2 +Abnormal eosinophil morphology 0.3130154434805604 0.2553748657166866 0.7984335815987209 1.0 1.0 11 O43909 1 +Antenatal onset 0.3128432040010507 0.2548754114430175 0.7988193280413196 1.0 1.0 11 O95235,P62140,Q7L590 3 +Abnormal parotid gland morphology 0.6822429906542073 0.2529915269231985 0.8002747607994836 1.0 1.0 2 Q13428 1 +Palmar pits 0.6822429906541919 0.2529915269231685 0.8002747607995067 1.0 1.0 2 Q9H488 1 +Impaired distal proprioception 0.4592882991556027 0.2528498783132157 0.8003842223793463 1.0 1.0 3 O14802,Q96RR1 2 +Gait imbalance 0.3203084423064022 0.2521290529784828 0.8009413141670174 1.0 1.0 25 Q15056,Q14839,Q7LG56,Q8NFV4,O94905,P42858,O43709,O15269,Q05086,P78347 10 +Dehydration 0.3208012677082696 0.251381849602807 0.8015188991721574 1.0 1.0 17 Q4G176,P05165,P26440 3 +Abnormal circulating proline concentration 0.4584288424836595 0.2508208751581698 0.8019526013356264 1.0 1.0 3 P30038 1 +Broad thumb 0.3136566586520205 0.2500313812861551 0.8025630804437116 1.0 1.0 29 Q96L73,O75175,P42858,Q13868 4 +Abnormal humerus morphology 0.6801326499849281 0.2488600003038458 0.8034690771548318 1.0 1.0 2 Q6ZRS2 1 +Failure of eruption of permanent teeth 0.6801326499849238 0.2488600003038378 0.8034690771548381 1.0 1.0 2 A6NHR9 1 +Talipes equinovalgus 0.6801326499849156 0.2488600003038214 0.8034690771548507 1.0 1.0 2 Q9Y3E5 1 +Abnormal serum insulin like growth factor 1 level 0.4574681319815453 0.2485635156870311 0.803698433115281 1.0 1.0 3 Q9NW13 1 +Large intestinal polyposis 0.3082697825912371 0.2484341177609667 0.8037985386693873 1.0 1.0 10 P31749 1 +Polyhydramnios 0.2328415608316509 0.2472660814844502 0.8047023069308834 1.0 1.0 53 P62140,O43909,Q9Y281,Q13724,Q04446,Q96ST3,Q8N9N2,Q15125 8 +Genu valgum 0.2968032369289377 0.2471808740804082 0.8047682464045132 1.0 1.0 35 Q9Y281,P46100,Q8NFV4,Q96L73,O43709,Q7RTS9 6 +Thoracic aortic aneurysm 0.2933168871399912 0.247175431711998 0.8047724581386142 1.0 1.0 36 Q9NXH9,P62140,O75175,O95394,Q8NFV4,P42858,O43709 7 +Chronic oral candidiasis 0.4093447560725002 0.2469759087790358 0.8049268686376629 1.0 1.0 4 Q03426 1 +Semilobar holoprosencephaly 0.409049773755658 0.2462347099636924 0.8055005478821795 1.0 1.0 4 Q8N3U4,A5YKK6,Q14683 3 +Hodgkin lymphoma 0.3097606400841225 0.2460578666686523 0.8056374380144935 1.0 1.0 11 O95394,P42771 2 +Squared iliac bones 0.6786252637925756 0.2459331507370924 0.8057339811931243 1.0 1.0 2 Q01970 1 +Choreoathetosis 0.307730447320422 0.2450916216648121 0.8063854900655536 1.0 1.0 31 P10515,P22033,Q8TCS8,Q16795,P37198,Q9H6K4,P51608,P08559,Q9H078,Q92947,Q9P0J0 11 +Wide intermamillary distance 0.3190819000784622 0.2437231636136055 0.8074452322783896 1.0 1.0 23 P62140,P23786,Q9NP72,Q06124,Q9UBM7,Q9BZK7,Q5SRE5,P08069,Q5T440 9 +Aplasia hypoplasia of the eyelid 0.3145362406037001 0.2436465850355541 0.8075045456555983 1.0 1.0 14 O15160,Q15427,Q6NUK1,Q9H9Y6,Q13428 5 +Trophic changes related to pain 0.4551917835939563 0.2432600512234416 0.8078039494752143 1.0 1.0 3 O15269 1 +Penetrating foot ulcers 0.4551917835939563 0.2432600512234416 0.8078039494752143 1.0 1.0 3 O15269 1 +Emg slow motor conduction 0.4551917835939563 0.2432600512234416 0.8078039494752143 1.0 1.0 3 O15269 1 +Caudate atrophy 0.4549009597598492 0.2425870850699674 0.8083252870332136 1.0 1.0 3 P42858 1 +Central hypoventilation 0.3476005547635341 0.2419293459311096 0.8088349106852442 1.0 1.0 7 O43819 1 +Abnormal renal tubule morphology 0.316919977376693 0.241877214553795 0.8088753061317333 1.0 1.0 25 P23786,P22033,Q15056,O43819,Q04446,Q8NFV4,O43709,P03915,P78347 9 +Motor regression 0.6744045824540223 0.2378459858595254 0.812000550356232 1.0 1.0 2 P11766 1 +Upper extremity joint dislocation 0.3174585838714089 0.2374514789620657 0.812306556997564 1.0 1.0 20 O75367,O43909,Q9Y2D4 3 +Metaphyseal irregularity 0.3101801496094122 0.2361331156010628 0.8133293778708959 1.0 1.0 13 Q7RTS9,P26373,Q9Y2D4 3 +Skin dimple 0.3046457943452804 0.2353949900933441 0.8139021741710566 1.0 1.0 31 O43909,Q15056,Q8NFV4,O43709,O95202,P78347,Q15125 7 +Reduced consciousness confusion 0.3388514346011181 0.2343336359343836 0.8147259750595106 1.0 1.0 128 Q12824,O43676,P18077,P38117,Q9UI10,P62857,Q9Y3D3,P40939,Q9NPL8,P30038,P19404,P26440,Q8IUX1,P62081,P08559,P42858,P28331,Q92947,Q96CU9,Q96IX5,Q9UMS0,P20674,Q86Y39,P61353,O75380,P31749,P62847,P62899,P03915,P55084,P60866,P05165,P22033,P23786,Q96RQ3,O43819,Q7LG56,P61313,P62244 39 +Long toe 0.3049129383906117 0.2326589470048693 0.8160262499705109 1.0 1.0 11 O60762,P23786 2 +Psoriasiform dermatitis 0.3717932406061245 0.2326481233367979 0.8160346554182671 1.0 1.0 5 P78536 1 +Mitral valve prolapse 0.3124315258516516 0.2319420904834736 0.816582992324383 1.0 1.0 26 O43909,P53701,Q15056,Q06124,Q9NZJ4,Q8NFV4,Q14697,O43709,P78347 9 +Vaginal neoplasm 0.3714544357272109 0.2317659033237342 0.8167198412173169 1.0 1.0 5 O43684,Q15645,O60566,O43683 4 +Disproportionate short limb short stature 0.3150574139434751 0.2315604120778527 0.8168794583728878 1.0 1.0 19 Q7RTS9 1 +Dysphonia 0.298136560088407 0.2313488237647926 0.8170438194163585 1.0 1.0 33 Q9BQP7,Q15056,O95140,O60333,Q8NFV4,O43709,Q9ULV3,P78347 8 +Upper limb amyotrophy 0.3127124207349994 0.2313203023812123 0.8170659753404548 1.0 1.0 16 Q8TB36,Q15120,O60568,P31483 4 +Pheochromocytoma 0.3161779105122487 0.2296698032443996 0.818348361211314 1.0 1.0 9 O60333,P36957,P31040 3 +Foot dorsiflexor weakness 0.2874894079221536 0.2277446981710368 0.8198447212939919 1.0 1.0 36 Q8TB36,Q99720,Q9Y281,Q9Y6X9,O95140,P51149,O43819,O60333,Q7LG56,Q9NZJ4,Q6DD88,O15269,Q15046,A6NHR9,P31483 15 +Elevated pulmonary artery pressure 0.3115165669615097 0.2262642270677401 0.8209959195916958 1.0 1.0 25 P03915,P11047,Q9UMS0,Q9NP81 4 +Lower limb spasticity 0.276524347542896 0.2261556406622347 0.8210803704156533 1.0 1.0 85 Q5T160,Q99720,P46100,P19404,Q9BSH4,Q8TD30,Q5MNZ6,Q9H6K4,Q04446,Q96KR1,Q9P0J0,P08559,P28331,Q8WVX9,Q96CU9,Q8TAF3,O75787 17 +Abnormal metacarpal morphology 0.2866367672706938 0.2250259475376998 0.8219590886530934 1.0 1.0 36 Q7RTS9,O43909,O75962 3 +Papilledema 0.3116799692177698 0.2243883365051632 0.8224551454410332 1.0 1.0 24 P31749,Q12824,P42858,O75175 4 +Pneumothorax 0.3409553626108479 0.2238894814805704 0.8228433005534115 1.0 1.0 7 P31153,Q6NUK1,Q9H078 3 +Ankle flexion contracture 0.3069921352705768 0.2231160787385747 0.8234451647313821 1.0 1.0 14 Q5JTV8,Q96L73,Q8TCS8 3 +Myoglobinuria 0.3009281948800797 0.2220774709559017 0.8242535755493254 1.0 1.0 11 P23786,P55084 2 +Abnormal circulating androgen level 0.3025185166904949 0.2207202017199127 0.82531030067161 1.0 1.0 12 P31749,Q12824,Q9NW13 3 +Prominent nose 0.3108868720602343 0.2205810085766018 0.8254186897998161 1.0 1.0 23 O43909,P54132 2 +Prematurely aged appearance 0.2598351392598993 0.2193382166265727 0.8263865940533419 1.0 1.0 42 P54886,Q8NFV4,Q6NUK1,Q9H2M9,P36543,P06748,Q15056,O94761,Q06124,P48651,P26639,O43709,Q02224,O60832,Q9BUR4,P78347,Q15042,O75431,P32322,Q9BZK7 20 +Proximal symphalangism 0.4443571012414313 0.2189015163522401 0.8267267652364143 1.0 1.0 3 P48651 1 +Abnormality of earlobe 0.3045437570343906 0.2175714042623208 0.8277630668327891 1.0 1.0 28 P10586 1 +Narrow nose 0.3657211828605842 0.2171174147214123 0.8281168426766481 1.0 1.0 5 P49589,Q9Y4L1,O75431,Q14683 4 +Poor suck 0.3021515204586062 0.2157249913246116 0.8292021195983765 1.0 1.0 29 Q5T160,P11047,O43819,Q9UBM7,P40939,Q05086,O75962,P55084 8 +Spastic tetraplegia 0.2634741122612476 0.2156407137540861 0.8292678173605041 1.0 1.0 41 Q8NBJ5,Q9Y3C6,Q86XL3,P00505,Q9NP72,P51608,Q9UGM6,Q5T440 8 +Abnormal eating behavior 0.3090103465375919 0.2154077032932213 0.8294494646163881 1.0 1.0 19 Q12824,P42858 2 +Overhanging nasal tip 0.6617425384383335 0.2145497808204069 0.8301183511405918 1.0 1.0 2 Q9H9E3 1 +Hemiparesis 0.3075499114633631 0.2130736951871113 0.8312694817208459 1.0 1.0 18 P31749,P03915,Q12824 3 +Hypertrophic cardiomyopathy 0.3200094391879866 0.2128392900066929 0.8314523168054517 1.0 1.0 119 O43676,Q00325,Q3LXA3,Q969Y2,Q8NFV4,Q9NPL8,Q9H2U2,Q9NYY8,P19404,Q15056,Q8IUX1,P08559,P28331,O43709,Q96CU9,Q96IX5,Q9BSH4,Q86Y39,O75380,P03915,P62140,O43819,Q9P0J0 23 +Hemorrhage of the eye 0.2971880329005714 0.2125031378679524 0.8317145300207343 1.0 1.0 11 P36543,Q92947,P29992,Q9Y3A5 4 +Abnormal glycosylation 0.308110145927597 0.2122844078523188 0.8318851589598453 1.0 1.0 22 O60762,O75340,Q9BT22,P39656,Q9H9E3,P46977,Q8N511,O75787 8 +Ventricular hypertrophy 0.2576316617165019 0.2118827122358415 0.832198538032215 1.0 1.0 42 P11047,P03915,Q969Y2,Q13724,P78536 5 +Abnormal urine magnesium concentration 0.6602351522460057 0.2118737789531291 0.8322055075524126 1.0 1.0 2 P29992 1 +Abnormality of vitamin metabolism 0.3039236508594173 0.2118023577478121 0.8322612290364302 1.0 1.0 27 P10515,P22033,Q4G176,P30038,P41440,Q9Y3A5 6 +Abnormality of limb epiphysis morphology 0.2913263669696206 0.2110296339918944 0.8328641474462279 1.0 1.0 33 Q7RTS9,O43909 2 +Severe intrauterine growth retardation 0.4405910735826265 0.2107823738953826 0.8330570931416756 1.0 1.0 3 Q92979,O14802 2 +Birth length less than 3rd percentile 0.4405910735826233 0.2107823738953757 0.833057093141681 1.0 1.0 3 Q9NXE4,Q9Y619 2 +Limitation of joint mobility 0.3042623278829667 0.2101139390103171 0.8335787465525633 1.0 1.0 108 O75367,Q12824,Q9H6K4,Q8NFV4,Q96L73,Q7RTS9,Q15022,O43909,P11047,Q8TCS8,O95140,Q9NP72,Q15056,P48651,Q04446,P51608,O60568,O43709,Q9BPU6,P31749,O60216,Q05086,Q03426,P78347,P23786,P46100,Q15427,Q9Y2D4 28 +Nyctalopia 0.2959884348483109 0.2100414529759898 0.833635319801582 1.0 1.0 31 O75695,Q96S66,Q13099,P50213,O95140,Q6P2Q9,P38435,O94906,Q92620,P40939,Q8TC12,Q9H9E3,O75643,Q03426 14 +Abnormal male reproductive system physiology 0.2648078769541909 0.2056307169637 0.8370793815800333 1.0 1.0 40 Q12824,Q15056,P54132,P57076,P51608,Q8NFV4,P31749,O43709,P78347 9 +Failure to thrive in infancy 0.2801352624147918 0.2053355226526862 0.8373099922341578 1.0 1.0 36 P20674,Q15056,Q96RQ3,Q3LXA3,Q8NFV4,O43709,Q9H9E3,Q03426,P78347,P55084 10 +Abnormal fingertip morphology 0.2892926127290542 0.2053125118885843 0.8373279692093336 1.0 1.0 33 Q9BZK7,O75175,Q86TI2,P42858 4 +Urethral stenosis 0.3022767386354587 0.2043785067578505 0.838057724823291 1.0 1.0 16 Q8NFV4,O60832,Q15056,O43709 4 +Abnormal preputium morphology 0.291251942389053 0.2036071178842904 0.838660530396248 1.0 1.0 10 Q96L73 1 +Sparse eyebrow 0.2827394602444206 0.2034111197958401 0.8388137091510517 1.0 1.0 35 P62857,P60953,Q15125 3 +Neoplasm of head and neck 0.2974866627253488 0.2033470450941068 0.8388637868981077 1.0 1.0 13 Q8N9N2,P42771,P54132 3 +Aplasia hypoplasia of the cerebellar vermis 0.2535046696458684 0.202154135757989 0.8397962271833579 1.0 1.0 74 P62140,Q12824,O60826,P00505,Q9NP72,Q8N201,Q96L73,P60953,P22570,Q96B26,Q03426,Q8NI27,Q8WVX9,Q9UGM6,Q9BPU6,Q15125 16 +Porokeratosis 0.3593301964725052 0.2014212972341487 0.8403691636701898 1.0 1.0 5 Q03426,Q15126 2 +Mesomelia 0.3321256038647314 0.2011857818326273 0.8405533086531451 1.0 1.0 7 Q6DKJ4,P38919,Q9UBM7,P21333,Q9NS87,P63000 6 +Abnormal metabolic brain imaging by mrs 0.3007933408671442 0.2007816757492745 0.8408692917866745 1.0 1.0 16 P03915 1 +Hip subluxation 0.3317351072056348 0.2002156404157091 0.8413119355416296 1.0 1.0 7 Q8NI27,Q9UBM7 2 +Pancreatic hypoplasia 0.3438967481781681 0.1999908613192224 0.8414877283570268 1.0 1.0 6 Q9Y3A5,Q9UKG1 2 +Gingival overgrowth 0.2893379383369753 0.1984437840903041 0.8426978637796017 1.0 1.0 32 O43909,Q96S52,Q8NFV4,Q9BZK7,O43709 5 +Exertional dyspnea 0.3020887226397459 0.1979573600200913 0.8430784252517107 1.0 1.0 23 Q9BZK7,P11047 2 +Cerebral calcification 0.291309048485231 0.1974780319374233 0.843453470915986 1.0 1.0 31 Q8NBJ5,Q9BUR4,Q12824,P23786,Q96AX1,P29992,Q9Y617,Q15046,P03915,Q9P2R7,O60832,P06748 12 +Areflexia of lower limbs 0.2995879619080887 0.1974224346308092 0.8434969747950416 1.0 1.0 26 O95140,Q15120,O95394,Q9H6K4,Q7LG56,O75787 6 +Verrucae 0.433894651079929 0.1967961976631794 0.8439870267580334 1.0 1.0 3 P16615 1 +Increased urine alpha ketoglutarate concentration 0.3564768370720729 0.1946322278117492 0.8456808713677071 1.0 1.0 5 P30038 1 +Hypochromic microcytic anemia 0.4328237577281337 0.1946134453317771 0.8456955764643197 1.0 1.0 3 P46100 1 +Pigmentary retinopathy 0.2196098886010641 0.1938404343683351 0.8463008253790842 1.0 1.0 53 O75695,P19404,P53701,P03915,P50213,Q9NQ48,Q9BSH4,Q7LG56,Q9P0J0,P08559,P40939,P28331,Q96CU9,Q16795,P55084 15 +Incoordination 0.2561737496137222 0.1921094214076495 0.8476564951516743 1.0 1.0 78 P11047,O75787,O95140,Q99653,Q9NXN4,Q96L73,P42858,O15020,Q7RTS9,P31483 10 +Downturned corners of mouth 0.2713425419337558 0.1904777459410373 0.8489347801103113 1.0 1.0 37 Q969N2,O75175,Q9NP72,P60953,O60568 5 +Retinal dystrophy 0.2261471506748996 0.1903272389583272 0.8490527101508363 1.0 1.0 58 O75695,P53701,Q13868,Q6P2Q9,Q9NQ48,O94906,Q92620,P57076,Q99700,P22570,Q03426,Q99798,P03915,Q9UGM6,Q16795 15 +Chronic kidney disease 0.2672722294264267 0.1893546164299061 0.8498148917765476 1.0 1.0 38 P11047,P23786,P22033,Q9NQ48,Q8IUX1,Q9NP81,Q92947,Q9NPF4 8 +Abnormality of the hairline 0.2791103421259374 0.1890536728132711 0.8500507503750567 1.0 1.0 95 P62140,O75175,O60826,Q12824,O15160,Q9NP72,P61353,Q96L73,Q9BZK7,P62847,P62857,O60934,P61313,Q9H9Y6,Q86W42 15 +Esophageal neoplasm 0.2998712994008228 0.18887955984749 0.8501872140923992 1.0 1.0 9 Q8N9N2,P54132 2 +Aortic root aneurysm 0.2954777236619872 0.1874821828960725 0.8512825919966824 1.0 1.0 26 Q9NXH9,P62140,O75175,P42858 4 +Male pseudohermaphroditism 0.3835839730469934 0.1869342695481488 0.8517121695645553 1.0 1.0 4 P46100 1 +Abnormal lung lobation 0.2947890706713333 0.186815790535262 0.8518050658208531 1.0 1.0 16 P31749 1 +Deviation of the hallux 0.2732939206163568 0.1865866389039029 0.8519847433794803 1.0 1.0 36 Q9NXH9,O75175,Q15056,Q8NFV4,P31749,P42858,O43709,P78347,Q9BPU6 9 +Abnormal circulating tyrosine concentration 0.4277006275619922 0.184378503470454 0.8537165324573841 1.0 1.0 3 P16930 1 +Wide mouth 0.2316891021944494 0.1842043934440867 0.8538531129884674 1.0 1.0 63 Q12824,P46100,Q15056,O15160,Q05086,P48651,Q8NFV4,P60953,O43709,Q9H9Y6,O75962,P78347,Q9BPU6 13 +Underdeveloped tragus 0.6436539041302272 0.1838213069551164 0.8541536404272951 1.0 1.0 2 Q5SRE5 1 +Functional abnormality of male internal genitalia 0.2858302674462312 0.1837766134157414 0.8541887034319633 1.0 1.0 31 Q15056,P54132,P57076,P51608,Q8NFV4,O43709,P78347 7 +Aplastic hypoplastic toenail 0.2752270399646182 0.1834077365255549 0.8544781059618416 1.0 1.0 35 Q15022,P62140,Q9BUR4,Q12824,O60832,Q15056,P23786,Q8NFV4,Q96L73,O43709,P15924,P78347,P14923,P06748 14 +Small nail 0.2223507667851324 0.1832603447954012 0.854593747686913 1.0 1.0 47 Q15022,P62140,Q12824,O60826,Q15056,P23786,P48651,Q8NFV4,Q96L73,O43709,P78347 11 +Abnormality of acid base homeostasis 0.3758000914038266 0.1831250547263509 0.8546998973481728 1.0 1.0 176 P00505,O43676,Q00325,P38117,Q969Y2,Q3LXA3,P11498,Q9Y3D3,P40939,Q9NPL8,Q9H2U2,Q8NI60,Q9UGM6,Q9NYY8,Q07021,P10515,P19404,Q8TCS8,Q99797,P26440,Q02218,Q8IUX1,P51608,P08559,P28331,Q9H078,Q9NP81,Q92947,Q96CU9,Q5T440,Q9UMS0,P14927,Q5T160,P55809,Q9BW92,P20674,P09622,Q15031,Q9BSH4,Q86Y39,Q4G0N4,Q4G176,Q9BRT2,O75380,Q9Y2R9,P08574,P03915,P55084,P05165,P22033,P23786,Q96RQ3,Q96RP9,O43819,Q6P4A7,Q7LG56,Q9P0J0,Q9P2R7,Q16795,O14949 60 +Abnormality of the mitochondrion 0.2874061718020559 0.1822979371319865 0.8553489174912072 1.0 1.0 103 O43676,Q00325,P38117,Q969Y2,P40939,Q9NPL8,P10515,P19404,Q9Y3D9,Q8TCS8,Q8IUX1,Q96EY7,P08559,P28331,Q96CU9,Q5T440,Q9UMS0,Q9BQP7,P20674,P09622,Q13148,Q9BSH4,Q86Y39,Q4G0N4,O75380,P03915,P23786,Q96RP9,Q7LG56,Q9P0J0,P22570,Q9P2R7,Q16795 33 +Abnormal reflex 0.2305534021986854 0.1816436230431532 0.8558624120546374 1.0 1.0 372 Q969N2,O14949,Q9H6K4,P11498,Q8NFV4,Q96L73,O15020,Q99798,Q7RTS9,Q9H0U9,Q8NI60,Q9UGM6,P41440,P30038,Q9H9E3,O75787,O75695,Q9NYY8,O43909,P11047,O75340,Q86XL3,O95140,Q8TCS8,Q99653,Q9NP72,P10515,P19404,Q9NXN4,Q15056,O60762,Q04446,Q96KR1,P08559,P42858,O43709,P28331,Q9H078,Q96CU9,Q8N9N2,Q96IX5,Q5T440,O60832,Q5T160,P20674,Q13148,Q9BSH4,Q8TD30,O95394,Q15120,Q92620,Q05086,P03915,P35251,Q99720,Q9Y281,P46100,Q9Y3C6,O15382,Q96RQ3,Q96RP9,O43819,O60333,Q7LG56,O60220,Q9Y3E5,Q99700,Q8WVX9,Q06265,Q9P0J0,Q99986 71 +Male reproductive system neoplasm 0.294153280754775 0.1813113580001159 0.856123191385987 1.0 1.0 18 P31749,O60934,Q9Y6D9 3 +Neonatal hyperbilirubinemia 0.4261158021712927 0.1812820834255261 0.8561461683873453 1.0 1.0 3 P43034,P11171 2 +Macrotia 0.2664351647056689 0.1810262955077909 0.8563469361598253 1.0 1.0 88 Q8NFV4,Q96L73,Q96ST3,Q15022,Q15056,Q9NP72,P48651,P51608,O60934,P42858,O43709,Q9BPU6,Q9NPF4,Q9NXH9,O75175,P31749,O60216,O75962,P62140,Q9BZK7,Q8NI27,Q8WVX9 22 +Spinal muscular atrophy 0.2852459248146096 0.1796531007128246 0.8574249144789303 1.0 1.0 12 Q99720,Q8N9N2,Q96B26,Q99986 4 +Solitary median maxillary central incisor 0.3797888386123702 0.1789119681916274 0.8580068251570618 1.0 1.0 4 Q8N3U4,A5YKK6,Q14683 3 +Single fiber emg abnormality 0.4248421593180095 0.1788176189170848 0.8580809103674585 1.0 1.0 3 O75340 1 +Muscle fiber tubular inclusions 0.4248421593180095 0.1788176189170848 0.8580809103674585 1.0 1.0 3 O75340 1 +Abnormality of hair pigmentation 0.2933178581088664 0.1787621791794124 0.8581244435017661 1.0 1.0 24 P12955,Q9BUR4,Q9Y2Q5,Q9UM00,P42704,Q9UBM7,Q05086,Q13724,O60832,P06748 10 +Abnormality of the kidney 0.1911802276759857 0.1774405130553484 0.8591623873508758 1.0 1.0 357 Q969N2,Q12824,O43676,P18077,P38117,P11498,Q8NFV4,Q96L73,P62857,P51809,Q9NPL8,P30038,Q9Y3A5,Q86W42,O43909,P11047,Q86XL3,P19404,Q15056,Q9NP72,Q07021,P42771,Q8N201,Q8IUX1,Q04446,O60934,P08559,P60953,P28331,O43709,Q9H078,Q9NP81,Q92947,Q96CU9,P62081,O60832,Q9NPF4,Q9BQP7,O60826,Q86Y39,Q9NWH9,Q9BRT2,O95394,P61353,P53680,O75380,P31749,Q07812,P62847,O60216,P62899,P03915,Q03426,P78347,Q15125,P36957,P60866,P46100,P23786,P54132,P22033,Q5JRA6,Q5SW96,Q15427,O43819,O60333,Q7LG56,Q9BT22,Q9BZK7,P61313,P62244 71 +Macroglossia 0.2660099741350757 0.1767247244782792 0.8597246192179511 1.0 1.0 37 Q12824,Q96S52,Q15056,P46100,Q8NFV4,P31749,O43709,Q05086,P78347 9 +Abnormal hair morphology 0.1669928603373141 0.1760401763657131 0.8602623791162816 1.0 1.0 352 Q12824,Q96L73,P62857,Q96ST3,Q9H9E3,Q13724,Q86W42,Q96S52,P19404,O15160,Q9NP72,Q9Y4W2,P42771,Q8N201,O60934,P08559,O60568,P42858,P60953,P28331,Q96CU9,O60832,Q9NXH9,P20674,O75175,O60826,Q13868,Q9BSH4,Q9BRT2,P61353,Q10567,P31749,P62847,P62899,Q9H9Y6,P03915,O75962,Q05086,P78536,Q15125,P62140,P54132,O43819,Q9BZK7,P61313,Q8WVX9,Q9P0J0 47 +Exodeviation 0.2910219752055004 0.1752806031844342 0.8608591522375171 1.0 1.0 25 P46100,O43819,P60953,Q8NI27,Q05086,Q9UGM6 6 +Feeding difficulties 0.2053432225605176 0.1743602276399118 0.8615823692347666 1.0 1.0 346 Q969N2,Q12824,P00505,O43676,Q969Y2,Q96L73,P62857,Q9Y3D3,Q96ST3,Q9NPL8,Q9H0U9,Q9H9E3,Q13724,Q9UGM6,P30038,O60762,Q15022,P11047,Q9ULK4,Q96S52,Q8TCS8,P19404,Q8IUX1,Q96EY7,P51608,P08559,P42858,P28331,Q9H078,Q9NP81,Q92947,Q96CU9,Q96B26,Q5T440,Q9UMS0,Q9BPU6,Q5T160,Q9NXH9,O75175,O60826,Q4G176,Q86Y39,Q8TD30,O75380,O60216,Q9H9Y6,Q05086,O75962,P17480,P46977,P55084,Q99720,P62140,P05165,P46100,P54132,Q9Y281,P23786,Q96RQ3,Q96RP9,O43819,Q7LG56,Q9BZK7,Q8NI27,Q06265,Q99986 66 +Myopia 0.2913791582615495 0.1730719662832299 0.8625948600644913 1.0 1.0 109 Q969N2,Q12824,Q3LXA3,Q8NFV4,Q96L73,Q86W42,O75695,P11047,Q15056,O15160,O60568,P42858,O43709,Q13868,Q10567,P31749,P46100,O43819,O60220 19 +Abnormality of the gingiva 0.2101563322398076 0.1729229279057111 0.8627120092752747 1.0 1.0 51 O43909,Q96S52,Q15056,O60832,Q8NFV4,Q9BZK7,O43709,P78347,Q9Y3A5 9 +Progressive spastic paraplegia 0.2849369040371642 0.1728836564148092 0.8627428784994549 1.0 1.0 29 P19404,Q9BSH4,Q96KR1,P08559,P28331,Q96CU9,Q9P0J0 7 +Skin vesicle 0.2792684814389457 0.1714731810225759 0.8638517165526902 1.0 1.0 11 Q9BUR4,O60832,Q9H488,P06748 4 +Platyspondyly 0.2636751392466175 0.1710921843369598 0.8641512812580145 1.0 1.0 37 Q7RTS9,O43909 2 +Abnormal conjugate eye movement 0.228818710564816 0.1710018009884555 0.8642223494710393 1.0 1.0 334 Q969N2,Q12824,O43676,Q3LXA3,Q8NFV4,Q96L73,P62857,Q96ST3,O15020,Q9NPL8,Q99798,Q8NI60,Q9UGM6,P30038,P10412,O75340,O60762,P11047,P10515,P19404,O15160,Q8N201,Q8IUX1,P08559,P60953,P42858,O43709,P28331,Q96CU9,Q9NPF4,Q9NXH9,O75175,Q15031,Q13868,Q13148,Q9BSH4,Q86Y39,P61353,O75380,P31749,P62847,P62899,Q9H9Y6,O75962,Q99720,P46100,O43819,Q9BZK7,P61313,Q8NI27,Q9P0J0 51 +Brachydactyly 0.2468760132875977 0.1701941172521644 0.8648574779805209 1.0 1.0 77 P62140,O43909,P46100,Q96S52,O60826,Q13868,P31749,Q9Y3D3,Q7RTS9,O75962 10 +Recurrent bacterial infections 0.2889341185525226 0.1693695402558648 0.8655059807071335 1.0 1.0 24 Q8N5M9,P57076,P78536 3 +Sarcoma 0.2265654762279927 0.1693331759509902 0.8655345821270564 1.0 1.0 63 P60866,Q12824,P18077,P42771,Q07812,P61353,P31749,O60934,P62857,P62081,P62847,P62899,P61313,P62244 14 +Upslanted palpebral fissure 0.2671204626942787 0.1691672276394755 0.8656651067896486 1.0 1.0 92 Q969N2,P62140,Q15125,O75175,O60826,P46100,Q13868,Q86XL3,Q9BRT2,P60953,O75962,Q86W42 12 +Abnormality of male internal genitalia 0.281815997014007 0.1685166507225883 0.8661768456024794 1.0 1.0 13 O60934,Q9Y6D9 2 +Steppage gait 0.288041545986768 0.1675267743522664 0.8669555823221833 1.0 1.0 24 O95140,P51149,Q15120,O43819,O60333,Q6DD88,O15269,Q15046,Q8TB36,P31483 10 +Hyperactive deep tendon reflexes 0.27692478601128 0.1666990917933235 0.8676068201818872 1.0 1.0 11 Q99700,O75787,O60220 3 +Hemolytic anemia 0.2734716614033535 0.1662620686362324 0.8679507153725248 1.0 1.0 33 Q969N2,O60934,O95394,P41440 4 +Muscular hypotonia of the trunk 0.2521517781611953 0.1660853135021675 0.8680898117630318 1.0 1.0 82 O43909,Q9BW92,P05165,Q6ZXV5,Q8TCS8,Q9NP72,Q99653,Q4G176,Q9H9E3,Q5MNZ6,Q96RP9,P51608,P42858,P22570,Q8WVX9,Q9UGM6 16 +Failure to thrive 0.2233835201905317 0.1648496631019421 0.869062313236797 1.0 1.0 312 Q16795,O43676,Q00325,P24928,P37198,Q96C23,Q3LXA3,Q969Y2,Q8NFV4,Q96ST3,P40939,Q9NPL8,Q99798,Q7RTS9,Q8N5M9,Q9H9E3,Q9Y3A5,O60762,P19404,Q8TCS8,Q15056,O15160,O15143,Q8IUX1,P48651,Q04446,P51608,P08559,P28331,O43709,Q9NP81,Q96B26,Q92947,Q96CU9,Q9UMS0,Q9NPF4,Q5T160,O60832,P20674,Q9BSH4,Q86Y39,Q8TD30,O95394,Q4G176,O75380,P31749,Q10567,O00116,O60216,Q9Y2R9,Q9H9Y6,P03915,O75962,Q03426,P46977,P78536,Q15125,P78347,P62140,P55084,P05165,P22033,Q96RQ3,O43819,O60333,Q7LG56,Q9Y2D4,Q9Y3E5,Q9BZK7,P22570,Q00059,Q9P2R7,Q06265,Q9P0J0 74 +Abnormal urine alpha ketoglutarate concentration 0.3163384615310247 0.1643005377795975 0.8694945583601956 1.0 1.0 7 Q02218,P30038 2 +Abnormal involuntary eye movements 0.2368992252272563 0.1642906906388907 0.8695023099135213 1.0 1.0 310 Q969N2,O43676,Q9H6K4,Q3LXA3,Q8NFV4,Q96L73,Q96ST3,O15020,Q9NPL8,Q99798,Q9H9E3,Q9UGM6,P41440,O75695,Q9NYY8,O43909,P11047,Q96S52,O75340,Q8TCS8,Q9NP72,O60762,P10515,P19404,Q15056,Q9NXN4,Q8IUX1,Q96EY7,P08559,P42858,O43709,P28331,Q9H078,Q96CU9,Q5T440,Q9NXH9,O75175,Q13868,Q9BSH4,Q86Y39,Q92620,O75380,Q05086,P03915,Q03426,Q8TAF3,Q15125,P35251,Q99720,P62140,Q96RP9,O43819,O60333,Q9BZK7,Q99700,P22570,Q8NI27,Q8WVX9,Q06265,Q9P0J0 60 +Premature skin wrinkling 0.285943960534711 0.1642396834564627 0.8695424623681967 1.0 1.0 18 Q06124,P32322,Q6NUK1,Q9BZK7,O60832 5 +Stage 5 chronic kidney disease 0.2769828382666365 0.1639073272215823 0.8698040988262694 1.0 1.0 31 P11047 1 +Reduced visual acuity 0.3076313592747587 0.1631340155071018 0.8704129180231097 1.0 1.0 126 Q12824,O43676,Q9H6K4,Q9UI10,Q9NPL8,Q99798,Q9UGM6,P10412,O75695,P11047,Q99653,Q8IUX1,P08559,P60953,P28331,Q96CU9,Q86Y39,O75380,P31749,O75962,P46100,O60220 22 +Abnormal external genitalia 0.1765756149470044 0.1628934835042667 0.8706023017110947 1.0 1.0 305 Q12824,P50213,Q8NFV4,Q96L73,P62857,Q96ST3,Q9H0U9,Q13724,Q86W42,Q15022,O75787,O75695,O60762,Q96S52,Q86XL3,Q15056,O15160,Q9NP72,Q9Y4W2,O94906,P42771,P48651,P51608,P62081,P60953,P42858,O43709,Q9BPU6,O60832,Q9NXH9,O75175,O60826,Q92620,Q9BRT2,P61353,P31749,P62847,O60216,P62899,Q9H9Y6,P46977,Q15125,P62140,P60866,P46100,P54132,Q9Y3E5,Q9BZK7,P22570,Q9H488,P61313,Q8NI27 52 +Abnormal branching pattern of the aortic arch 0.4155609167671846 0.1615065710249574 0.8716944363697663 1.0 1.0 3 Q8WYQ5,Q96DF8 2 +Tachypnea 0.2854511147212676 0.1612836900431693 0.8718699685459692 1.0 1.0 20 P05165 1 +Palpitations 0.2850232961675822 0.1612393415898732 0.8719048963728115 1.0 1.0 19 P36957,P31040,P46100,O60333,Q7LG56,Q9H1K1,Q02978,Q14126,P14923 9 +Abnormal lip morphology 0.1933542307491725 0.1609379270466485 0.8721422901826175 1.0 1.0 298 Q969N2,Q12824,Q96L73,Q9UGM6,Q86W42,O43909,Q96S52,Q86XL3,O15160,Q9NP72,Q9Y4W2,P10586,Q8N201,O60934,P08559,O60568,P42858,P60953,O43709,O75175,O60826,Q13868,Q9H9Y6,O75962,P78536,P62140,P46100,P54132,Q9Y2D4,Q9BZK7 30 +Abnormal enchondral ossification 0.2774232565063705 0.1607615491597616 0.8722812105822941 1.0 1.0 30 O43909,P38435,O00116,P61011,Q7RTS9,Q15738,O95202,Q9Y3A5,Q15125 9 +Abnormal pancreas morphology 0.2840913024051408 0.1606349916384183 0.8723808934275612 1.0 1.0 18 O75369,Q9NQH7,Q5F1R6,Q9BXW9,Q9Y3E5,Q14697,P61011,Q9Y5S9,Q9Y3A5,Q9UKG1 10 +Variable expressivity 0.242563396808245 0.1598718587939699 0.8729820167853837 1.0 1.0 77 Q5T160,P03915,O95140,Q13868,Q969Y2,Q8NI60,Q15125 7 +Neck muscle weakness 0.2835111645804571 0.1595248231666188 0.8732554026742827 1.0 1.0 18 P11047 1 +Visual impairment 0.2393047173479148 0.1589829862538415 0.8736822783398883 1.0 1.0 291 Q969N2,Q12824,O43676,Q9H6K4,Q969Y2,Q9UI10,Q8NFV4,Q9NPL8,Q99798,Q9UGM6,P10412,O75695,O75340,P11047,Q9ULK4,Q96S52,O95140,O15160,Q99653,Q9NP72,P10515,P19404,Q8IUX1,O60762,P08559,P60953,P42858,O43709,P28331,Q96CU9,Q9NPF4,Q9NXH9,O75175,Q86Y39,Q5MNZ6,O75380,P31749,Q9H9Y6,P03915,O75962,P46100,O43819,O60220,P22570,Q8NI27 45 +Abnormality of hindbrain morphology 0.2349632129357161 0.1587037585403998 0.8739022768253033 1.0 1.0 290 Q969N2,Q12824,P00505,Q9H6K4,Q3LXA3,Q8NFV4,Q96L73,O15020,Q9ULV3,Q99798,Q8NI60,Q9UGM6,P41440,O75787,O60762,Q96S52,Q15056,O15160,Q99653,Q9NP72,Q9NXN4,Q8N201,P08559,P60953,P42858,Q96B26,O43709,P28331,Q9H078,Q96CU9,Q5T440,Q9BPU6,Q9NPF4,Q5T160,Q9BQP7,Q9NXH9,O60832,O60826,Q13868,Q9UHD1,Q9Y320,P31749,O60216,O75477,P17480,P46977,Q03426,P78347,Q15125,P35251,Q99720,P62140,Q9Y3C6,Q7LG56,Q9Y3E5,Q9BZK7,Q99700,P22570,Q8NI27,Q8WVX9,Q06265,Q99986 62 +Melanoma 0.2842244591050908 0.1585598234928067 0.8740156844655564 1.0 1.0 21 P31749,O60934 2 +Short long bone 0.250930289191181 0.1585594623616485 0.8740159690071037 1.0 1.0 39 Q969N2,P26373,Q96S52,Q15427,Q9NWH9,Q9Y2D4,Q01970,O00116,P39019,Q7RTS9,Q9H9E3 11 +Abnormal sacrum morphology 0.2542960123538288 0.1578659853231162 0.8745624016916713 1.0 1.0 38 O43909,Q15056,Q8NFV4,Q96L73,P39019,O43709,O95202,P78347,Q15125 9 +Abnormality of globe location 0.2001134249797581 0.1573078057250776 0.8750022687718431 1.0 1.0 285 Q12824,Q96L73,P62857,Q96ST3,Q9H9E3,Q9UGM6,Q86W42,O43909,O15160,Q9Y4W2,Q8N201,O60568,P42858,P60953,Q9NPF4,Q5T160,Q9NXH9,O75175,O60826,Q13868,Q8TD30,P61353,P31749,P62847,P62899,Q9H9Y6,O75962,Q15125,P62140,P46100,Q9Y2D4,Q9BZK7,P61313,Q8NI27,Q8WVX9 35 +Abnormality of the urinary system physiology 0.1810773883018367 0.1570286520753476 0.8752222671257783 1.0 1.0 284 Q969N2,O43676,Q9H6K4,P11498,Q8NFV4,Q96L73,Q9NPL8,P30038,Q86W42,P11047,P19404,Q15056,P26440,Q02218,Q8IUX1,O60934,P28331,O43709,Q9H078,Q9NP81,Q92947,Q96CU9,Q9NPF4,P55809,Q86Y39,O95394,Q9BRT2,P53680,O75380,P03915,P05165,P46100,P54132,Q96RQ3,O43819,O60333,Q9BZK7 37 +Abnormal cardiac ventricular function 0.2828850995864771 0.1564969344777907 0.8756413354057173 1.0 1.0 23 P03915,Q969Y2 2 +Stroke 0.2708891095827807 0.1559483401126078 0.8760737415027466 1.0 1.0 32 O95235,Q15056,P51608,Q8NFV4,O43709,P03915,P78347 7 +Renal hypoplasia aplasia 0.2566797132063352 0.1554234157469518 0.8764875253695552 1.0 1.0 89 P18077,Q9UBM7,Q8NFV4,Q96L73,P62857,P39019,Q86W42,P08708,Q86XL3,Q15056,P33992,Q06124,P62081,P60953,O43709,P57678,P61353,P62847,O60216,P62899,P78347,P60866,P46100,Q15427,O43819,P61313,Q15738,P62244 28 +Abnormality of the anus 0.2110675004094153 0.1554007723482351 0.8765053753167493 1.0 1.0 56 Q15022,O43909,O60826,O60934,Q96ST3,Q9H488,P78536,O60832,Q86W42 9 +Patent foramen ovale 0.2800562227395944 0.154876366714779 0.8769187854433331 1.0 1.0 26 P62140,P09001,P08069,Q96AX1,O75431,P38646,Q15233,Q8N9N2,P29401 9 +Abnormality of the curvature of the cornea 0.2429770327664179 0.1548176280382877 0.8769650936059878 1.0 1.0 79 P10412,Q969N2,Q07021,O75175,O75695,Q9NXH9,Q15056,P50213,O94906,Q8N201,Q92620,Q10567,Q8NFV4,Q96L73,P42858,O43709,Q9BPU6 17 +Pancreatic cysts 0.3676543359880683 0.1547197172860865 0.8770422850288364 1.0 1.0 4 Q9NQH7,Q14697 2 +Abnormal nasal bridge morphology 0.1831325800518611 0.1545168171293996 0.8772022523034217 1.0 1.0 275 Q969N2,Q12824,P50213,P18077,P38117,P61586,Q8NFV4,P62857,Q96ST3,P39019,Q9H9E3,Q9UGM6,O75695,O75340,O43909,O60762,Q15056,O15160,Q9NQ48,Q9NP72,O94906,Q8N201,P51608,O60934,P62081,P60953,P42858,O43709,P08559,Q5SRE5,O95202,P08069,Q9BPU6,Q5T160,Q9NXH9,O75175,O60826,Q92620,Q9BRT2,P61353,Q01970,P31749,P62847,O60216,P62899,Q9H9Y6,O75962,P78347,Q15125,P60866,P46100,Q5JRA6,Q15427,Q8WVX9,P61313,Q9NX62,P62244 57 +Aplasia hypoplasia of the ovary 0.2761585917217993 0.1543582718494612 0.8773272535111551 1.0 1.0 14 Q9NQ48,O75616,P51809,Q15031 4 +Abnormal blood glucose concentration 0.2648293630922976 0.1535248162620117 0.8779844217361776 1.0 1.0 96 P05165,P19404,O43676,Q96RQ3,Q86Y39,Q4G176,Q8IUX1,P11498,O75380,Q96L73,P28331,Q9NPL8,Q00059,Q9H078,Q92947,Q96CU9,Q9UGM6 17 +Leukoencephalopathy 0.2660503244839191 0.1534027951201395 0.8780806407898012 1.0 1.0 97 Q8NBJ5,Q9NXH9,O43676,Q86Y39,Q8IUX1,Q9UI10,P11498,P08559,P60953,P28331,Q9NPL8,Q96CU9,Q9UGM6 13 +Glucose intolerance 0.2883233582325171 0.1530492091924483 0.8783594690593886 1.0 1.0 115 O43676,P50213,Q8NFV4,Q96L73,Q9NPL8,Q9Y3A5,O75695,P19404,Q15056,O94906,P42771,Q8IUX1,Q9Y6M1,P28331,O43709,Q9NP81,Q96CU9,P08069,O60832,Q86Y39,Q92620,O75380,P03915,P78347,Q9UKG1,P54132,Q5JRA6,Q6P2Q9,Q7LG56,P17096,Q9Y3E5,P61011 32 +Impaired adp induced platelet aggregation 0.4107358262967415 0.1529590726503445 0.8784305507059971 1.0 1.0 3 Q86YV9,P27797 2 +Abnormality of the diaphragm 0.2761312949211917 0.1519764716218227 0.879205492997311 1.0 1.0 28 P62857 1 +Abnormality of upper lip 0.2147181277787324 0.1508903274137915 0.8800622307298089 1.0 1.0 262 Q969N2,Q12824,Q96L73,Q9UGM6,Q86W42,O43909,Q96S52,Q86XL3,O15160,Q9NP72,Q9Y4W2,P10586,Q8N201,O60934,P08559,O60568,P42858,P60953,O43709,O75175,O60826,Q13868,Q9H9Y6,O75962,P62140,P46100,Q9Y2D4,Q9BZK7 28 +Renal cell carcinoma 0.2786869097613351 0.1507634066368627 0.8801623535228285 1.0 1.0 25 O60333,P31749,Q9NWH9,Q07812 4 +Chronic constipation 0.2784309900095043 0.1503021465939408 0.880526239492587 1.0 1.0 25 P62140,Q13724,O75962 3 +Arthropathy 0.3223664352550586 0.1502780394763243 0.8805452581834448 1.0 1.0 6 O95163,Q9Y3Z3,Q6DD88,O15269,P40763 5 +Chronic otitis media 0.2697175920842504 0.1496142405247069 0.8810689723369385 1.0 1.0 31 Q03518,O95394,P57076,Q8NFV4,Q96L73,O43709 6 +Abnormal saccadic eye movements 0.274811537517225 0.1495601359672233 0.8811116612358567 1.0 1.0 28 O95140,Q99653,O43819,Q9NXN4,O15020 5 +Increased adipose tissue 0.4086248492159287 0.1493170726270978 0.8813034442819847 1.0 1.0 3 O14802,O75431 2 +Cerebellar cyst 0.2382807144450884 0.1486635364170598 0.8818191351616005 1.0 1.0 41 P62140,Q12824,O60826,P08559,P60953,Q15125 6 +Skin plaque 0.3211590703290098 0.1477388396655498 0.8825488783415818 1.0 1.0 6 P00338,Q06136,Q92990,P22314,P16615 5 +Abnormal thumb morphology 0.2946654987713125 0.1468573674824196 0.8832446028043162 1.0 1.0 124 P18077,Q9H6K4,Q8NFV4,Q96L73,P62857,Q96ST3,Q15022,O43909,Q86XL3,Q15056,P62081,P60953,P42858,O43709,Q9BPU6,Q9NPF4,Q9NXH9,O75175,Q13868,P61353,P62847,O60216,P62899,O75962,P78347,P60866,Q15427,Q9Y3E5,P61313,Q06265,P62244 31 +Retinal atrophy 0.2681757143237634 0.1468081816240307 0.8832834266588963 1.0 1.0 31 Q9NXH9,O75175,P50213,Q9NQ48,Q92620,Q9Y296,P42858,P04439,Q8TC12,Q9BPU6 10 +Vascular dilatation 0.2281383432975683 0.1467553691746273 0.8833251134012681 1.0 1.0 71 Q9NXH9,P62140,Q6ZXV5,O75175,O95394,Q8NFV4,Q96L73,O60568,P42858,O43709 10 +Hypoplasia of the uterus 0.2793244394364071 0.1460693404941548 0.8838666495248666 1.0 1.0 9 O75616,P53701,Q15031 3 +Vertebral segmentation defect 0.2632753931545467 0.1460106103071167 0.8839130123828529 1.0 1.0 33 P46100,O60826,Q15056,Q8NFV4,O60216,O43709,P78347,Q15125 8 +Hyperreflexia 0.2821850834536344 0.1458766482965474 0.8840187663288579 1.0 1.0 244 Q969N2,O14949,Q9H6K4,P11498,Q8NFV4,Q96L73,O15020,Q7RTS9,Q9H9E3,Q8NI60,Q9UGM6,O75787,O75695,O75340,O43909,O60762,Q86XL3,P10515,O95140,Q9NP72,Q99653,P19404,Q15056,Q9NXN4,Q96KR1,P08559,P42858,O43709,P28331,Q9H078,Q96CU9,Q96IX5,Q5T440,Q5T160,P20674,Q9BSH4,Q8TD30,O95394,Q92620,Q05086,P03915,Q99720,P46100,Q9Y3C6,O15382,Q96RQ3,Q96RP9,O60220,Q99700,Q8WVX9,Q06265,Q9P0J0,Q99986 53 +Abnormality of the pinna 0.1905899805631348 0.1453149673476901 0.8844621979221032 1.0 1.0 242 Q8NFV4,Q96L73,P62857,Q96ST3,Q96S52,O15160,Q9NP72,Q9Y4W2,P10586,Q8N201,O60934,O60568,P42858,O43709,Q9NPF4,Q9NXH9,O75175,P61353,P31749,P62847,P62899,Q9H9Y6,O75962,Q15125,P62140,P46100,P54132,Q9BZK7,P61313,Q8NI27,Q8WVX9 31 +External ophthalmoplegia 0.2753911056535145 0.1449057259154448 0.8847853055286508 1.0 1.0 18 Q9BQP7,Q07021,Q7LG56,P03915 4 +Amenorrhea 0.2541404288537002 0.1444306032796272 0.885160452229075 1.0 1.0 36 Q9UI10,O75616,Q12824,P31749 4 +Central diabetes insipidus 0.6171239071450074 0.1442556316825554 0.8852986125610449 1.0 1.0 2 P35222 1 +Abnormality of the palpebral fissures 0.2068639221933513 0.1442004436795745 0.8853421906020218 1.0 1.0 238 Q969N2,Q96L73,P62857,Q13724,Q86W42,O75340,Q86XL3,O15160,Q9NP72,Q8N201,O60934,P60953,P42858,O43709,Q9NPF4,Q9NXH9,O75175,O60826,Q13868,Q9BRT2,P31749,Q9H9Y6,O75962,Q15125,P62140,P46100,Q9BZK7 27 +Capillary malformation 0.2729281736286333 0.1439026997608758 0.8855773037784238 1.0 1.0 16 Q8NFV4,Q15056,O43709 3 +Increased circulating iga level 0.319180397872459 0.1436352624362696 0.885788493972844 1.0 1.0 6 O95394 1 +Anemic pallor 0.6165209526680705 0.1434325069524326 0.8859486115491964 1.0 1.0 2 Q9BXW9 1 +Cerebellar atrophy 0.3130507200948872 0.1422888114264438 0.8868518837945947 1.0 1.0 145 Q969N2,Q9H6K4,O15020,Q9ULV3,Q99798,Q8NI60,Q9UGM6,P41440,O75787,O60762,Q96S52,O15160,Q99653,Q9NXN4,P60953,P42858,P28331,Q9H078,Q96CU9,Q5T440,Q9NPF4,Q5T160,Q9BQP7,Q9NXH9,Q13868,Q9UHD1,Q9Y320,P17480,P46977,Q03426,P35251,Q7LG56,Q9Y3E5,Q9BT22,Q99700,P22570,Q8WVX9,Q06265 38 +Deviation of the thumb 0.2727760258014453 0.1419182715364417 0.8871445617972791 1.0 1.0 17 O75369,P34897,P36776,Q9UBM7,Q9Y3E5,Q96ST3,P60953,O60216,Q14683,Q15029 10 +Distal muscle weakness 0.2295914814001764 0.1419165060375866 0.8871459563471118 1.0 1.0 74 O75340,O43909,P11047,Q99720,O95140,Q13148,Q99653,P35251,O60333,Q7LG56,P41440,Q5T440,P31483 13 +Death in childhood 0.2701990519802698 0.1415320686348295 0.8874496279089059 1.0 1.0 28 Q02218,Q96IX5,Q9NPL8,Q5T160 4 +Abnormal myelination 0.2670826196118022 0.1408625533283712 0.8879785252316506 1.0 1.0 226 O43676,Q3LXA3,Q969Y2,Q9UI10,P11498,Q9NPL8,Q99798,Q9UGM6,P41440,O75787,O60762,O75340,Q6ZXV5,Q96S52,Q8TCS8,O95140,O15160,P19404,Q8IUX1,Q96KR1,P08559,P28331,Q92947,Q96CU9,Q5T440,O75175,Q13868,Q9BSH4,Q86Y39,Q8TD30,O95394,O75380,Q05086,P03915,P35251,Q99720,Q9Y3C6,Q96RP9,O43819,O60333,Q7LG56,P22570,Q8WVX9,Q9P0J0 44 +Abnormal hair quantity 0.1474483820083257 0.1405794671680229 0.8882021699575258 1.0 1.0 225 Q12824,Q96L73,Q9H9E3,Q13724,P19404,O15160,Q9NP72,O60934,P08559,P60953,P28331,Q96CU9,O60832,Q9NXH9,P20674,Q13868,Q9BSH4,Q9BRT2,P31749,Q9H9Y6,P03915,O75962,Q15125,P62140,P54132,O43819,Q9P0J0 27 +Retinal hemorrhage 0.3047702260921038 0.1403544663939867 0.8883799322110706 1.0 1.0 7 Q92947 1 +High palate 0.1881182511209596 0.1403010077956689 0.8884221680954916 1.0 1.0 224 Q969N2,Q96L73,P62857,Q96ST3,Q13724,Q9UGM6,O75340,P11047,O15160,Q9NP72,P42858,Q9NPF4,Q9NXH9,O75175,O60826,O95394,P61353,P31749,P62847,P62899,Q9H9Y6,O75962,Q15125,P62140,Q9Y281,P46100,Q9Y2D4,P61313,Q8NI27 29 +Retinal vascular tortuosity 0.2716153665094004 0.1400171638514671 0.8886464291856782 1.0 1.0 17 Q8NFV4,P03915,O43709 3 +Astigmatism 0.203339505772352 0.1384606268717118 0.889876385045312 1.0 1.0 56 Q969N2,P10412,O75175,Q8N201,Q96L73,P42858 6 +Unusual infection 0.2233809115412842 0.1383521892746027 0.8899620809763764 1.0 1.0 217 Q12824,P00505,Q8NFV4,Q96ST3,Q9NPL8,Q7RTS9,Q8N5M9,Q7L590,Q9H9E3,Q9Y3A5,Q86W42,O75787,O43909,P11047,O15143,Q15056,O60934,P08559,P60953,Q9H078,O43709,O60832,O95235,O60826,Q03518,O95394,P31749,O75962,P14174,Q03426,P78536,P46100,O75083,P54132,P57076,Q9BZK7,Q06265 37 +Abnormality of the lens 0.2230721522681858 0.1383521856877768 0.8899620838109901 1.0 1.0 217 P50213,P18077,Q9H6K4,Q96C23,P38117,Q3LXA3,P61586,Q96L73,P62857,Q8NHU6,Q8NFV4,P39019,Q9H9E3,O75695,O75340,P11047,Q6ZXV5,Q8TCS8,Q99797,O15160,Q9NP72,Q15056,O94906,Q8N201,P51608,P62081,O60568,Q9H078,O43709,P57678,Q5SRE5,O60832,P53701,Q03518,Q92620,P61353,P31749,P62847,O60216,P04439,P62899,Q9H9Y6,P03915,Q9H444,P61313,P78347,Q03426,Q15125,P60866,P23786,Q9Y6X9,Q6P2Q9,O60333,Q7LG56,P22570,Q06136,Q8WVX9,P62244 58 +Abnormal cardiac septum morphology 0.1562486107410139 0.1377953575647417 0.8904021534863851 1.0 1.0 215 Q969N2,Q12824,Q8NFV4,Q96L73,P62857,Q13724,Q86W42,P19404,Q15056,P08559,P60953,P28331,O43709,Q96CU9,O60826,Q15031,Q9BSH4,P61353,P62847,P62899,O75962,P62140,P46100,P61313,Q9P0J0 25 +Decreased muscle mass 0.2708336567832083 0.1374393021675418 0.8906835671519542 1.0 1.0 18 Q9NP72,Q7LG56,Q9Y285,P31749,O95202 5 +Cutaneous photosensitivity 0.2712313849163586 0.137098648759497 0.8909528205182644 1.0 1.0 24 P54132,P22830,O60934,Q06136,Q03426 5 +Hypertelorism 0.191145430654773 0.1361254086164184 0.891722141315469 1.0 1.0 209 Q96L73,P62857,Q96ST3,Q9UGM6,O43909,O15160,Q8N201,P60953,P42858,Q9NPF4,Q9NXH9,O75175,O60826,P61353,P31749,P62847,P62899,Q9H9Y6,O75962,Q15125,P62140,P46100,Q9BZK7,P61313,Q8NI27,Q8WVX9 26 +Bruising susceptibility 0.2572254016625601 0.1357061467411544 0.892053588281883 1.0 1.0 33 Q9BZK7,O60568 2 +Nephrolithiasis 0.2702918622068757 0.1356303808212188 0.8921134869514933 1.0 1.0 24 Q9BQP7,Q15056,P53680,Q8NFV4,O43709,P50454,P78347 7 +Abnormality of the philtrum 0.222395345569295 0.1355690822826042 0.8921619485163395 1.0 1.0 207 Q969N2,Q12824,Q8NFV4,Q96L73,Q96ST3,Q86W42,O60762,O43909,Q96S52,Q9NP72,P10586,Q8N201,O60934,P08559,O60568,P42858,P60953,O43709,Q9NXH9,O75175,O60826,Q13868,O75962,P62140,P46100,Q9BZK7,Q8WVX9 27 +Biventricular hypertrophy 0.6104914078987007 0.1353861053797912 0.8923066092868135 1.0 1.0 2 P36543 1 +Multiple joint contractures 0.2705708028588633 0.1350988419622259 0.8925337257652364 1.0 1.0 22 P41440 1 +Abnormal penis morphology 0.2131644473209349 0.1350124128889296 0.8926020601277473 1.0 1.0 205 Q12824,P50213,P18077,Q9UBM7,Q9UBX3,Q8NFV4,P51809,P62857,Q96L73,Q96ST3,P39019,Q9H0U9,Q15046,A6NHR9,Q86W42,Q15022,O75787,O75695,P08708,Q15056,O15160,Q9NQ48,Q9NP72,Q06124,O94906,P48651,P51608,P62081,P60953,O43709,O95202,Q9BPU6,O60832,P53701,O60826,Q14839,Q92620,P61353,P78330,P31749,P62847,O60216,P62899,Q9H9Y6,P46977,P78347,P60866,P46100,Q6P2Q9,Q9BZK7,Q9H488,P61313,Q8NI27,P62244 54 +Abnormal cellular phenotype 0.2093339740611589 0.1350123752645604 0.8926020898752871 1.0 1.0 205 Q969N2,Q12824,O43676,Q00325,Q969Y2,Q9NPL8,Q13724,O75787,O43909,P10515,P19404,Q8TCS8,Q8IUX1,Q96EY7,O60934,P08559,P28331,Q96CU9,Q5T440,Q9UMS0,P20674,Q13148,Q9BSH4,Q86Y39,O95394,O75380,P31749,P03915,Q03426,P14174,P78536,P54132,Q96RP9,Q7LG56,O60220,P22570,Q9P0J0 37 +Slanting of the palpebral fissure 0.1903945003305352 0.135012319882418 0.8926021336629313 1.0 1.0 205 Q969N2,Q96L73,P62857,Q86W42,O75340,Q86XL3,O15160,O60934,P60953,P42858,Q9NPF4,O75175,O60826,Q13868,Q9BRT2,P31749,Q9H9Y6,O75962,Q15125,P62140,P46100 21 +Telecanthus 0.2420580024287105 0.1347601721037315 0.8928014965733031 1.0 1.0 38 P10412,Q9BZK7,P46100,Q15125 4 +Intrauterine growth retardation 0.1953857112828836 0.1344558446620308 0.8930421248249292 1.0 1.0 203 Q12824,O43676,Q969Y2,Q96ST3,Q9NPL8,Q9H9E3,Q9UGM6,P19404,Q8TCS8,Q9NP72,Q8IUX1,Q96EY7,O60934,P08559,O60568,P28331,Q96CU9,Q5T440,O60832,Q9NPF4,Q15031,Q86Y39,Q9BRT2,O75380,P54132,Q96RP9,Q6P4A7,Q00059 28 +Abnormal rectum morphology 0.2510937408536311 0.1342268548392957 0.8932231909699198 1.0 1.0 35 Q15056,O15160,P42771,Q8NFV4,P31749,O43709,Q9H9Y6 7 +Abnormal cns myelination 0.3021216775911807 0.1340630389427341 0.8933527263991077 1.0 1.0 144 O43676,Q3LXA3,Q969Y2,Q9UI10,P11498,Q9NPL8,O75787,O75340,Q96S52,Q8TCS8,O15160,Q8IUX1,P08559,P28331,Q96CU9,O75175,Q9BSH4,Q86Y39,Q8TD30,O95394,O75380,Q99720,Q9Y3C6,O43819,Q8WVX9 25 +Abnormality of chorioretinal pigmentation 0.3272471014933306 0.1330730599640844 0.894135600666103 1.0 1.0 5 Q5XKP0,P04181,Q96AX1 3 +Impaired collagen induced platelet aggregation 0.6086825444678892 0.1330375375501583 0.8941636936726065 1.0 1.0 2 P27797 1 +Plantar hyperkeratosis 0.2409402736908655 0.1329461070254499 0.8942360023850298 1.0 1.0 38 Q9BUR4,P31040,O60832,O15446,Q9H4L7,Q06136,P40123,P15924,Q96IJ6,P31749,Q14126,P16615,P14923,P06748 14 +Arnold chiari type i malformation 0.3552799858637283 0.1323575290367884 0.8947015059801255 1.0 1.0 4 P62140 1 +Bicornuate uterus 0.2714751887129227 0.1322312719159846 0.894801366879509 1.0 1.0 9 Q15427,Q15031 2 +Hand polydactyly 0.2404261439016721 0.1321275416706425 0.8948834117815914 1.0 1.0 38 O43909,O60826,P54132 3 +Abnormality of the chin 0.2305370867100745 0.1313009177155842 0.8955372658451259 1.0 1.0 80 P11047,Q96S52,O43709,Q7RTS9,O75962,Q86W42 6 +Abnormal glucose homeostasis 0.2254408903926741 0.1308416503161447 0.8959005740081187 1.0 1.0 190 O43676,P50213,P38117,P11498,Q8NFV4,Q96L73,P40939,Q9NPL8,Q9UGM6,Q9Y3A5,O75695,P19404,Q15056,O95140,O94906,P42771,Q8IUX1,Q9Y6M1,P28331,O43709,Q9H078,Q9NP81,Q92947,Q96CU9,P08069,O60832,P14927,P09622,Q4G176,Q86Y39,Q92620,O75380,Q9H845,Q9Y2R9,P03915,P78347,P55084,Q9UKG1,P05165,P23786,P54132,Q5JRA6,Q6P2Q9,Q96RQ3,Q7LG56,P17096,Q9Y3E5,P61011,Q00059 49 +Abnormal morphology of the great vessels 0.2070674565665199 0.1302838280030227 0.8963418743966005 1.0 1.0 188 Q969N2,Q12824,Q8NFV4,Q96L73,P62857,Q9Y3D3,Q86W42,O60762,Q6ZXV5,Q15056,O15160,P60953,P42858,O43709,Q9NXH9,O75175,O60826,Q15031,O95394,P61353,P62847,P62899,Q9H9Y6,P62140,P57076,P61313 26 +Abnormal myocardium morphology 0.2304007467158025 0.1297322138455032 0.8967782949733669 1.0 1.0 186 Q969N2,O43676,Q00325,P40123,Q3LXA3,Q969Y2,Q8NFV4,P40939,Q9NPL8,Q14126,Q9H2U2,Q7L590,Q9UGM6,Q9Y3A5,Q9NYY8,Q07021,P19404,Q15056,Q99797,Q8IUX1,Q04446,P08559,P28331,O43709,Q9H078,Q96CU9,Q96IX5,P14923,O95235,Q9BQP7,P53701,P09622,Q9BSH4,Q86Y39,O75380,Q9H845,P03915,P78347,P55084,P62140,P05165,P22033,P23786,Q5JTZ9,O43819,Q7LG56,Q9BT22,Q9P0J0,P61011,Q16795 50 +Infantile onset 0.21264806713542 0.1297281102967989 0.8967815416952205 1.0 1.0 186 Q969N2,P50213,P18077,P62857,O15020,Q9NPL8,P40939,P39019,Q99798,Q8TB36,O75787,O60762,Q6ZXV5,Q96S52,Q8TCS8,O95140,Q99797,P10515,P19404,P51608,P08559,P28331,P57678,Q9NP81,Q96CU9,Q9NXH9,P35241,P20674,Q9Y320,Q5MNZ6,Q9BRT2,P78330,P31749,Q9Y2R9,Q03426,P55084,P23786,Q5JRA6,Q5ST30,Q8WVX9,Q9P2R7,Q9P0J0 42 +Abnormality of globe size 0.2167528439165651 0.1296630702155098 0.8968330015450776 1.0 1.0 70 Q9NP72,O15160,Q8N201,Q3LXA3,P31749,Q9BZK7,Q9H9Y6,Q15125 8 +Abnormal toenail morphology 0.2048016527669556 0.1293067085407824 0.8971149633531061 1.0 1.0 46 Q15022,P62140,Q9BUR4,Q12824,O60832,Q15056,P23786,P51149,Q8NFV4,Q96L73,O43709,P15924,P78347,P14923,P06748 15 +Abnormality of the neck 0.2304488437630511 0.1288997343041226 0.8974369869105163 1.0 1.0 183 P62857,Q9Y3D3,Q9ULV3,Q7RTS9,Q96S52,O15160,Q9NXN4,Q8N201,O60934,P60953,O43709,O75175,O60826,P61353,P31749,P62847,P62899,Q9H9Y6,Q15125,Q99720,P62140,P46100,Q9Y281,Q9Y2D4,Q9BZK7,P61313 26 +Short nose 0.2553406227939678 0.1287699017619877 0.897539722122854 1.0 1.0 103 Q969N2,P62140,O43909,P46100,O60826,Q12824,Q9NP72,Q8N201,Q8NFV4,Q9BZK7,O60568,Q96ST3,O43709,Q8WVX9,O75962 15 +Abnormal finger phalanx morphology 0.1981986156863736 0.1286154438813962 0.8976619453600809 1.0 1.0 182 O75367,Q12824,Q96L73,P62857,Q7RTS9,O43909,Q96S52,P42858,Q9NPF4,Q9NXH9,O75175,O60826,Q13868,P61353,P62847,O75962,Q15125,P54132,P61313 19 +Abnormal circulating carboxylic acid concentration 0.2412676229983553 0.1269646370167461 0.8989683875614454 1.0 1.0 92 P38117,P11498,P30038,P41440,Q9Y3A5,Q99797,Q8IUX1,P08559,Q92947,P20674,P09622,Q4G176,Q4G0N4,P03915,P05165,P22033,P23786,O15382,Q96RQ3,Q7LG56,Q9P2R7,Q9P0J0 22 +Hallux valgus 0.2648083515665097 0.1269252723828967 0.8989995439380813 1.0 1.0 20 Q15056,P31749,Q8NFV4,O43709,P78347 5 +Anorectal anomaly 0.2342102427059607 0.1268471996595656 0.8990613375091712 1.0 1.0 86 Q15022,O43909,P60866,O60826,Q15056,O60832,O15160,P42771,P31749,O60934,Q8NFV4,Q96ST3,O43709,Q9H488,Q9H9Y6,P78536,Q86W42 17 +Tremor 0.2590822377592144 0.1268272353238138 0.8990771391261747 1.0 1.0 175 Q9H6K4,Q8NFV4,Q96L73,O15020,Q9ULV3,Q8NI60,Q9UGM6,P41440,O75787,O60762,Q15056,O95140,O15160,Q96KR1,P42858,O43709,Q92947,Q8TD30,Q15120,P31749,Q05086,P03915,O75962,P35251,Q99720,O60333,Q6P4A7,Q7LG56,O60220,Q8NI27,Q8WVX9 31 +Abnormal adipose tissue morphology 0.2042205994834398 0.1264172350846115 0.8994016599766879 1.0 1.0 62 P54132,O95140,P31749,Q9BZK7,P03915 5 +Abnormal blood chloride concentration 0.3944511459589901 0.1264008987080588 0.8994145907931153 1.0 1.0 3 Q13618,Q9H4A3 2 +Congenital malformation of the great arteries 0.2606506015617153 0.1260728091008633 0.8996742909012476 1.0 1.0 111 Q969N2,P62140,O60762,Q12824,O60826,Q6ZXV5,Q15031,O15160,Q15056,P57076,Q8NFV4,Q96L73,Q9Y3D3,P60953,O43709,Q9H9Y6,Q86W42 17 +Abnormal renal physiology 0.2195123587530092 0.1258419387399434 0.8998570433247779 1.0 1.0 172 O43676,P38117,P11498,Q8NFV4,P51809,Q96L73,Q9NPL8,P30038,Q07021,P11047,P19404,Q15056,Q9NQ48,Q9NQH7,Q8IUX1,P28331,O43709,Q9H078,Q9NP81,Q92947,Q96CU9,Q9NPF4,Q86Y39,Q4G0N4,O95394,Q9BRT2,P53680,O75380,O60216,P03915,P78347,P36957,P23786,P22033,O43819,O60333,Q7LG56,Q9BT22,Q9BZK7 39 +Abnormal size of the palpebral fissures 0.2432452616032931 0.1255598117911214 0.900080376659925 1.0 1.0 95 Q9NXH9,O75175,Q13868,Q9NP72,O95394,Q8N201,Q8NFV4,Q9BZK7,P42858,O43709,Q13724,Q86W42 12 +Glaucoma 0.2559228879184754 0.1255041158293981 0.9001244668431068 1.0 1.0 107 P50213,P18077,Q9UBM7,Q3LXA3,P61586,Q8NFV4,P62857,P39019,O75695,P08708,Q86XL3,Q15056,O94906,P62081,O43709,P53701,O60826,Q13868,Q92620,P61353,P31749,P62847,O60216,P62899,P78347,Q15125,P60866,Q6P2Q9,Q06136,Q7LG56,P61313,Q53H12,P62244 33 +Embryonal neoplasm 0.2626562243607099 0.1254046994608164 0.9002031678552971 1.0 1.0 25 Q12824,P54132 2 +Feeding difficulties in infancy 0.2237201333559426 0.1250148195330049 0.9005118180913088 1.0 1.0 169 Q969N2,Q969Y2,Q96L73,Q9Y3D3,Q9NPL8,Q13724,P11047,Q8TCS8,Q5T160,O75175,O60826,Q8TD30,Q9H9Y6,O75962,Q99720,P62140,P05165,P46100,P54132,Q96RQ3,Q99986 21 +Abnormal circulating amylase level 0.309464179547815 0.1245283503700268 0.9008969547302286 1.0 1.0 6 Q5F1R6,P61011,Q9Y3A5 3 +Abnormality of the musculature of the limbs 0.2570926371863694 0.1241923056093454 0.9011630143091311 1.0 1.0 165 Q12824,P18077,P37198,P62857,P40939,P39019,Q7RTS9,Q9H9E3,Q9UGM6,P31483,O75340,O43909,P11047,Q8TCS8,O95140,P62081,O60568,Q5T440,Q9BW92,Q15120,P61353,P31749,P62847,P62899,P17480,Q8TAF3,P55084,Q15125,Q99720,Q9Y281,P05165,P46100,P60866,O43819,O60333,Q7LG56,Q96IJ6,P61313,Q8WVX9,Q16795,P62244 41 +Wide nasal bridge 0.2521918613337938 0.124100536222506 0.9012356735984196 1.0 1.0 165 Q969N2,P50213,P18077,P61586,Q8NFV4,P62857,Q96ST3,P39019,Q9UGM6,O75695,O75340,Q15056,O15160,Q9NP72,O94906,Q8N201,P51608,P62081,P60953,P42858,O43709,P08559,Q5SRE5,O95202,P08069,Q9BPU6,Q9NXH9,O75175,O60826,Q92620,P61353,P62847,O60216,P62899,Q9H9Y6,P78347,P60866,P46100,P61313,Q9NX62,P62244 41 +Narrow mouth 0.2185240199385983 0.1238791430387941 0.9014109671730636 1.0 1.0 75 O43909,O75175,O15160,P31749,P42858,Q9H9Y6,Q9NPF4 7 +Functional motor deficit 0.2641996631821297 0.1230057315405872 0.9021025593237446 1.0 1.0 159 Q12824,Q969Y2,Q9ULV3,Q7RTS9,Q8NI60,Q9UGM6,P30038,P31483,O75787,O75340,P11047,O95140,Q99653,Q9NXN4,Q8IUX1,P42858,Q8TD30,P31749,P03915,Q8TAF3,Q99720 21 +Abnormal consumption behavior 0.2618669602379396 0.1229503588862949 0.9021464074818932 1.0 1.0 23 Q12824,P42858 2 +Retrognathia 0.2233844596819972 0.1226948992394553 0.9023487031649712 1.0 1.0 80 Q96L73,Q96ST3,P39019,Q13724,Q86W42,Q15022,O15160,Q8N201,O60934,Q5SRE5,P08069,Q5T440,P53701,Q9H9Y6,Q15125,P54132,Q5JRA6,Q15427,O95602 19 +Abnormality of refraction 0.2331633488747952 0.1225717473180591 0.902446228082258 1.0 1.0 160 Q969N2,Q12824,Q3LXA3,Q8NFV4,Q96L73,Q96ST3,Q86W42,P10412,O75695,P11047,Q15056,O15160,Q8N201,O60568,P42858,O43709,Q9NXH9,O75175,Q13868,Q10567,P31749,P46100,O43819,O60220 24 +Bradykinesia 0.2605182129937091 0.1225434325571355 0.9024686509590256 1.0 1.0 25 Q9BSH4,Q7LG56,Q99700,P42858,Q96IX5,O75787 6 +Fragile nails 0.2653233192498587 0.122335807878489 0.9026330743799402 1.0 1.0 9 Q10567,Q96ST3,P15924 3 +Abnormality of the midface 0.2218045595145776 0.1219768849290294 0.9029173247105078 1.0 1.0 158 Q969N2,P62857,P10412,O43909,Q96S52,O15160,Q9Y4W2,Q8N201,O60934,O60568,P60953,O75175,O60826,Q9H9Y6,Q15125,P62140,P46100,P54132,Q9BZK7 19 +Abnormal hair pattern 0.2636340688658031 0.1218602999410453 0.9030096572936656 1.0 1.0 122 P62140,Q9NXH9,O75175,O60826,P54132,Q12824,O15160,Q9NP72,P61353,Q96L73,P62847,P62857,P42858,Q9BZK7,P61313,O60934,Q9H9Y6,Q86W42 18 +Macule 0.2117561278662777 0.1216350325650361 0.9031880675006704 1.0 1.0 71 Q9NXH9,P62140,O75175,P54132,O60333,P31749,O60934,Q96ST3,P42858,Q9H488 10 +Encephalopathy 0.2493763975517419 0.1213765910154323 0.903392757445124 1.0 1.0 106 O60762,P05165,P19404,Q8TCS8,O43676,Q86Y39,Q8TD30,Q96CU9,Q8IUX1,O75380,P28331,Q9NPL8,Q9H078,Q92947,P03915,P30038,Q5T440 17 +Deviation of the hand or of fingers of the hand 0.2609751465796439 0.1212732353578343 0.9034746186186218 1.0 1.0 120 O75367,Q9H6K4,Q8NFV4,Q96ST3,Q7RTS9,Q13724,Q96S52,Q15056,Q9NP72,P51608,P60953,O43709,Q9BPU6,O75175,P31749,O60216,Q05086,O75962,P78347,Q15125,P46100,P54132,Q5JRA6,Q15427,Q9Y2D4,Q9Y3E5 26 +Vomiting 0.2429244522731506 0.1208801863096434 0.9037859361102044 1.0 1.0 100 P55809,P05165,P46100,P19404,O43676,P26440,Q96RQ3,Q86Y39,Q4G176,Q9NWH9,Q96CU9,Q8IUX1,O75380,P28331,Q9NPL8,Q9Y2R9,P03915,Q03426 18 +Abnormal ventricular septum morphology 0.1858139292813433 0.1208356773883807 0.903821190673438 1.0 1.0 154 Q12824,P18077,Q8NFV4,Q96L73,P62857,P39019,Q86W42,P19404,Q15056,P62081,P08559,P28331,O43709,Q5SRE5,O95202,Q96CU9,P08069,P53701,O60826,Q15031,Q9BSH4,P61353,P62847,O60216,P62899,P78347,P62140,P60866,P46100,Q15427,Q9P0J0,P61313,Q16795,P62244 34 +Abnormal cardiac atrium morphology 0.1738051610044723 0.1208348261896877 0.9038218648915396 1.0 1.0 154 Q969N2,P62140,Q12824,O60826,P57076,P61353,Q96L73,P62847,P62857,O43709,P61313,Q7L590,Q86W42 13 +Abnormality of the cerebrospinal fluid 0.2547556803842089 0.1203353720275478 0.9042174848622048 1.0 1.0 149 Q12824,O43676,Q9NPL8,Q8NI60,P30038,P19404,Q8TCS8,O95140,Q02218,Q8IUX1,P08559,P28331,Q96CU9,Q5T160,O60826,Q9BSH4,Q86Y39,O75380,P31749,P03915,Q15125,P62140,O15382,O43819,P57076,Q9P0J0 26 +Abnormality of reproductive system physiology 0.2476214474931511 0.1202285688274329 0.904302087264352 1.0 1.0 150 Q12824,P50213,Q9UI10,Q8NFV4,Q96L73,Q86W42,O75695,Q15056,O15160,Q9Y4W2,O94906,P48651,P51608,O75616,O60934,P42858,O43709,Q9BQP7,Q15031,Q92620,P31749,O60216,Q9Y2R9,P03915,P78347,P46100,P54132,Q7LG56,P57076,Q9BT22,Q9BZK7 31 +Increased megakaryocyte count 0.3899276236429445 0.1196485852694835 0.9047615306645092 1.0 1.0 3 O75533,P27797 2 +Dermal translucency 0.2627022340077083 0.1183687217704899 0.9057755079267552 1.0 1.0 9 P62140,Q6NUK1,P32322 3 +Open mouth 0.2447310499973077 0.1181454169738071 0.9059524378813656 1.0 1.0 33 Q969N2,O43909,P46100,Q86XL3,P31749 5 +Adducted thumb 0.2538738365690018 0.1180547592863306 0.9060242695588354 1.0 1.0 28 Q86XL3,Q15056,Q8NFV4,O43709,Q06265,Q9NPF4 6 +Flared metaphysis 0.2490825417826771 0.1175412364332188 0.906431168553932 1.0 1.0 12 Q9H9E3,Q9Y2D4 2 +Abnormality of the middle ear 0.1863010972863451 0.1172298049873742 0.9066779487879104 1.0 1.0 141 P50213,Q8NFV4,Q96L73,P62857,Q8N5M9,O75695,Q15056,O15160,O94906,O60934,P42858,O43709,Q9BPU6,Q9NXH9,O75175,Q03518,O95394,Q92620,O60216,Q9H9Y6,P78347,P36957,P54132,O60333,P57076 25 +Hyperpituitarism 0.256811002256132 0.1169302914616789 0.9069152936866682 1.0 1.0 19 P31749,Q12824 2 +Abnormality of the urethra 0.1978374934902981 0.1166908650440641 0.9071050294577414 1.0 1.0 139 Q12824,P18077,Q9UBM7,Q9UBX3,Q8NFV4,P51809,P62857,Q96L73,Q96ST3,P39019,Q15046,A6NHR9,Q86W42,O75787,P08708,Q15056,Q06124,P48651,P51608,P62854,P62081,P60953,O43709,O95202,O60832,P53701,O60826,P61353,P78330,P62847,O60216,P62899,P78347,P60866,P46100,P61313,P62244 37 +Abnormal urine protein level 0.1916425158712992 0.1153635265311611 0.9081569875098052 1.0 1.0 59 P36957,P11047,Q15056,O60333,Q8NFV4,O43709,Q9NP81,P03915,P78347,Q9NPF4 10 +Thin vermilion border 0.2029459945020891 0.1153397416470165 0.9081758392627975 1.0 1.0 134 P62140,O75175,P46100,Q12824,Q13868,Q86XL3,Q9Y4W2,Q9BZK7,P60953,P42858,Q9UGM6,Q86W42 12 +Abnormal scalp morphology 0.2343674247985839 0.1146201177682968 0.9087462331308565 1.0 1.0 127 P62140,Q15125,O75175,O60826,Q12824,O15160,Q9NP72,P61353,Q96L73,Q9BZK7,P62847,P62857,O60934,P61313,Q9H9Y6,P78536,Q86W42 17 +External genital hypoplasia 0.1938297850644535 0.1144823828290082 0.908855411041624 1.0 1.0 131 P50213,Q8NFV4,Q96L73,Q96ST3,Q9H0U9,Q13724,Q86W42,Q15022,O75695,O60762,Q15056,O15160,Q9NP72,O94906,P48651,O43709,Q9BPU6,O60832,O60826,Q92620,O60216,Q9H9Y6,P46977,P46100,Q9BZK7,Q8NI27 26 +Abnormality of upper lip vermillion 0.1856500007751501 0.1141877319995422 0.909088976743842 1.0 1.0 130 Q969N2,P62140,P46100,Q12824,Q13868,Q9Y4W2,Q9BZK7,P60953,Q9UGM6,Q86W42 10 +Abnormal leukocyte count 0.2362183508938441 0.1138926654422435 0.909322879863054 1.0 1.0 120 P62857,Q7L590,Q9H9E3,Q8N5M9,Q9Y3A5,O75787,O43909,O15143,P26440,O60934,Q9H078,Q9NP81,O60832,O95394,P61353,P62847,P62899,Q03426,P60866,P05165,P46100,P54132,Q9Y3C6,O75083,Q9BZK7,P61313 26 +Abnormal myeloid leukocyte morphology 0.2358858705647803 0.1138029093906998 0.9093940322192184 1.0 1.0 110 P18077,P40123,P62857,Q14126,Q8N5M9,Q9H9E3,P41440,Q9Y3A5,O43909,P62081,Q9H078,O60832,O95394,P61353,P62847,P62899,Q03426,P60866,P05165,P22033,P46100,Q9Y3C6,O75083,Q9BZK7,P61313,P62244 26 +Cerebellar hypoplasia 0.1975351131953065 0.1136812289712347 0.9094904931547094 1.0 1.0 128 Q969N2,Q12824,P00505,Q3LXA3,Q96L73,Q9UGM6,Q9NP72,Q8N201,P60953,Q96B26,Q9BPU6,O60832,Q5T160,O60826,Q15125,P62140,Q9Y3C6,Q9Y3E5,Q99700,P22570,Q8NI27,Q8WVX9,Q99986 23 +Displacement of the urethral meatus 0.1957444264456402 0.1136712805167286 0.9094983797515408 1.0 1.0 128 Q12824,P18077,Q9UBM7,Q9UBX3,P51809,P62857,Q96L73,Q96ST3,P39019,Q15046,A6NHR9,Q86W42,O75787,P08708,Q06124,P48651,P51608,P62854,P62081,P60953,O95202,O60832,P53701,O60826,P61353,P78330,P62847,O60216,P62899,P60866,P46100,P61313,P62244 33 +Absent eyebrow 0.3034713292027723 0.1136085142564881 0.9095481376545697 1.0 1.0 6 P14923,P15924 2 +Osteomyelitis 0.2505946690912951 0.1135947516328272 0.909559048010998 1.0 1.0 15 P51149,O95394,P61011,O15269,Q9Y3A5 5 +Long philtrum 0.2116233372087129 0.1135802810899138 0.909570519590688 1.0 1.0 127 Q969N2,P62140,O43909,O75175,Q9NXH9,Q13868,Q8N201,Q8NFV4,Q96L73,P08559,O60568,P42858,P60953,O43709,Q96ST3,Q8WVX9,O75962 17 +Absent speech 0.2351099594832411 0.113423077865864 0.9096951442780594 1.0 1.0 115 Q5T160,O43909,Q12824,Q96S52,Q6ZXV5,Q8TCS8,Q9UGM6,Q8TD30,Q9Y4W2,Q5MNZ6,Q9BZK7,P60953,P42858,O75962 14 +Abnormality of the cervical spine 0.2338801029195263 0.1131798981648903 0.9098879321955406 1.0 1.0 115 P18077,P62857,P39019,Q7RTS9,O43909,Q8N201,P51608,O60934,P62081,Q5SRE5,O60826,P61353,P62847,O60216,P62899,Q15125,P62140,Q9Y281,P46100,P60866,Q99575,Q15427,Q9Y2D4,Q9BZK7,P61313,Q06265,P62244 27 +Abnormality of mouth size 0.1902473205228534 0.1131014268367799 0.9099501438002612 1.0 1.0 126 Q12824,Q8NFV4,Q96ST3,O43909,Q15056,O15160,P48651,P51608,P60953,P42858,O43709,Q9BPU6,Q9NPF4,Q9NXH9,O75175,P31749,Q9H9Y6,Q05086,O75962,P78347,P46100,Q15427 22 +Abnormal large intestine morphology 0.2166355589384516 0.1129229362336699 0.9100916521502198 1.0 1.0 85 P18077,Q8NFV4,P62857,O15143,Q15056,O15160,P42771,P62081,O43709,Q07812,P61353,P31749,P62847,P62899,Q9H9Y6,P78347,P60866,P54132,P61313,P62244 20 +Ulnar deviation of the hand or of fingers of the hand 0.2469892261834492 0.1127417298421427 0.9102353165100774 1.0 1.0 13 Q9Y3E5,Q9Y2D4,Q9BPU6,Q9NW13 4 +Abnormality of the nail 0.1975698008672913 0.1126039391081732 0.9103445619590904 1.0 1.0 124 O75367,Q12824,Q8NFV4,Q96L73,Q96ST3,Q15022,O60762,Q15056,O15446,P48651,O60568,O43709,O60832,O60826,P10321,Q10567,P31749,Q03426,P78347,P78536,Q15125,P62140,P23786,P54132,Q9H488 25 +Abnormal upper limb bone morphology 0.231102207487114 0.1125783454838259 0.9103648536915724 1.0 1.0 109 Q969N2,O75367,Q8NFV4,Q96L73,Q7RTS9,Q9H9E3,Q15022,O43909,Q96S52,Q15056,P48651,P42858,O43709,Q9BPU6,Q9NXH9,O75175,Q13868,O00116,P31749,O60216,O75962,P78347,Q15427,Q9Y2D4 24 +Abnormal uvea morphology 0.2304433509617752 0.1124593763756027 0.9104591783141354 1.0 1.0 108 P61586,Q8NFV4,Q96ST3,P40939,O75695,O75340,P11047,Q15056,O15160,O43709,O95202,P08069,O60826,P31749,P04439,Q9H9Y6,Q05086,P14174,P78347,Q9UBC2,P36957,P54132,O60333,Q96IJ6 24 +Tooth malposition 0.2235815444308764 0.1123060739280788 0.910580725975354 1.0 1.0 95 P24928,Q9UBM7,P61586,Q15233,Q8NFV4,Q96ST3,A6NHR9,Q86W42,Q96S52,Q15056,O15160,Q06124,Q06210,P51608,P60953,O43709,O60216,Q9H9Y6,O15347,O75962,Q05086,P78347,P62140,P46100,P28340,Q9BZK7,Q15738 27 +Increased nuchal translucency 0.2521990998629315 0.1115051230848111 0.9112158033018274 1.0 1.0 19 Q8NFV4,O60216,Q15056,O43709 4 +Abnormal aortic morphology 0.2092032222908378 0.1112977826242455 0.9113802136922872 1.0 1.0 118 P18077,Q9UBM7,Q8NFV4,Q96L73,P62857,P39019,P08708,Q6ZXV5,Q15056,Q06124,P62854,P62081,P42858,O43709,Q9BPU6,Q9NXH9,O75175,P53701,Q14839,O95394,P61353,Q9Y296,P62847,P62899,P78347,P62140,P60866,Q5SW96,P61313,P62244 30 +Abnormal nipple morphology 0.1906116606736706 0.1110564958664857 0.9115715465380172 1.0 1.0 62 Q969N2,O60762,P62140,P23786,O60826,Q9NP72,Q06124,P10586,Q9UBM7,Q15233,Q9BZK7,O60216,Q5SRE5,O95202,P08069,Q5T440 16 +Alopecia of scalp 0.2736892425165608 0.1110187843426077 0.9116014510595094 1.0 1.0 8 Q15125 1 +Hypertrichosis 0.2229786883162518 0.1107749900510062 0.9117947783170026 1.0 1.0 105 Q9NXH9,Q12824,P19404,P54132,Q9NP72,Q9BSH4,O43819,Q9BRT2,Q96CU9,P08559,P60953,P28331,P03915,O75962,Q9P0J0 15 +Abnormal cortical bone morphology 0.2501847315322337 0.1106878788380449 0.9118638581982328 1.0 1.0 17 Q86XL3,Q96C36,P48651,P31749,Q15738 5 +Abnormal epiphyseal ossification 0.2498277038682713 0.1102872583774988 0.9121815619613308 1.0 1.0 17 Q7RTS9 1 +Bundle branch block 0.2464215938227109 0.1102759253736193 0.9121905495698612 1.0 1.0 14 P62140,Q99996,P14923,Q9HD47 4 +Hypoplasia of penis 0.2123468207078081 0.1097913319522018 0.912574865585285 1.0 1.0 110 P50213,Q9UBM7,Q8NFV4,P51809,Q96L73,Q96ST3,Q9H0U9,A6NHR9,Q86W42,Q15022,O75695,Q15056,O15160,Q9NQ48,Q9NP72,O94906,O43709,Q9BPU6,P53701,O60826,Q14839,Q92620,O60216,Q9H9Y6,P46977,P78347,P46100,Q6P2Q9,Q9BZK7,Q8NI27 30 +Delayed gross motor development 0.194596026537221 0.1096796803387605 0.91266341591921 1.0 1.0 113 Q9NYY8,O43909,Q99720,O75175,Q6ZXV5,O95140,Q9NXH9,Q9Y281,P10515,P42858,P22570,Q9H078,Q8WVX9,O75962 14 +Renal insufficiency 0.2108873823696436 0.1095581296968434 0.912759818355732 1.0 1.0 86 Q8NFV4,Q96L73,P30038,P11047,Q15056,Q9NQ48,Q9NQH7,Q8IUX1,Q9H078,O43709,Q9NP81,Q92947,Q9NPF4,P53680,O60216,P78347,P23786,P22033,Q9BT22 19 +Hypogonadism 0.2158523894072971 0.1093987718923549 0.9128862077911166 1.0 1.0 96 Q12824,P50213,Q8NFV4,P51809,O75695,Q15056,O15160,Q9Y4W2,O94906,P48651,P51608,O43709,Q9BQP7,Q92620,P31749,Q9Y2R9,P03915,P78347,P46100,Q7LG56,Q9BT22,Q9NW13 22 +Abnormality of dental structure 0.204168052307015 0.1093764820731424 0.9129038864086004 1.0 1.0 78 Q9UBM7,P61586,Q8NFV4,Q9Y3A5,Q86W42,Q15056,O15160,P48651,O43709,O60832,P53701,P31749,Q9H9Y6,P78347,P62140,Q5JRA6,P61011,Q9NW13,P50454 19 +Abnormality of the breast 0.2035020033893296 0.1092345493374035 0.9130164578496938 1.0 1.0 110 Q969N2,P62140,P46100,O60826,P54132,Q9NP72,Q9Y4W2,P10586,P31749,Q9BZK7,Q8NI60 11 +Aplasia hypoplasia affecting the eye 0.2022956201754144 0.1089570832832068 0.9132365301860884 1.0 1.0 109 P62140,P11047,Q9NPF4,O15160,Q9NP72,O60333,Q8N201,Q3LXA3,Q8NFV4,Q9BZK7,Q96ST3,O43709,Q9H9Y6,Q9UBC2,Q15125 15 +Hematological neoplasm 0.2110722731659737 0.1086945890478935 0.9134447337417808 1.0 1.0 90 P18077,Q96L73,P62857,P39019,Q9Y3A5,P08708,P11766,Q06124,P42771,P62854,O60934,P62081,O60832,Q13492,O95394,Q07812,P61353,P62847,P62899,P60866,P46100,P54132,P61011,P61313,P62244 25 +Abnormality iris morphology 0.2087008189508726 0.1086599640443548 0.9134721978319352 1.0 1.0 86 P61586,Q8NFV4,Q96ST3,O75340,P11047,Q15056,O15160,O43709,O95202,P08069,O60826,P31749,Q05086,Q9H9Y6,P78347,Q9UBC2,P36957,O60333,Q96IJ6 19 +Abnormal cell morphology 0.2868437125442508 0.1084188119406539 0.9136634793224973 1.0 1.0 7 Q99700,Q7LG56 2 +Increased body weight 0.2056082715854938 0.1081833551004959 0.913850248163984 1.0 1.0 104 Q969N2,Q12824,P50213,Q8NFV4,Q96ST3,O75787,O75695,Q15056,Q9Y4W2,O94906,P51608,O43709,Q15031,Q92620,P31749,O60216,Q05086,P78347,P46100,P54132,Q9Y2D4,Q8NI27 22 +Neoplasm by histology 0.2007313325343672 0.1080203525900764 0.91397954764124 1.0 1.0 105 Q12824,P18077,P51809,P62857,Q96L73,P42771,O60934,P62081,Q92947,O60832,Q07812,P61353,P31749,P62847,P62899,Q03426,P36957,P60866,P54132,O60333,P61313,P62244 22 +Constipation 0.2069376169018023 0.1073622298370923 0.9145016174911555 1.0 1.0 95 P62140,P60866,P05165,Q96S52,P46100,Q15056,Q13724,Q05086,Q7LG56,Q8NFV4,Q96L73,O43709,Q8WVX9,P03915,O75962 15 +Thin upper lip vermilion 0.2015314103674029 0.106852826341043 0.9149057379710142 1.0 1.0 98 P62140,P46100,Q12824,Q13868,Q9Y4W2,Q9BZK7,P60953,Q9UGM6 8 +Neoplasm of the gastrointestinal tract 0.2020371901892987 0.1063977210445768 0.9152668011583944 1.0 1.0 93 Q12824,P18077,P62857,P42771,O60934,P62081,Q8N9N2,Q9NWH9,Q07812,P61353,P31749,P62847,O60216,P62899,P60866,P46100,P54132,Q9H488,P61313,P62244 20 +Patchy hypopigmentation of hair 0.3383424878537672 0.1055276907793869 0.9159570985915576 1.0 1.0 4 Q9UM00 1 +Irregular hyperpigmentation 0.19396785206709 0.105420548666547 0.9160421114365422 1.0 1.0 76 Q9NXH9,P62140,O75175,P54132,O60333,P31749,O60934,Q96ST3,P42858,Q9H488 10 +Anteverted ears 0.379674306393252 0.1053383875250179 0.9161073035622592 1.0 1.0 3 O15347,P27635 2 +Cutis laxa 0.2300046473451423 0.1052741561815223 0.9161582693841844 1.0 1.0 34 Q15022,Q15056,P48651,Q8NFV4,Q96L73,Q9Y3D3,O43709,O75787 8 +Abnormal circulating hormone concentration 0.1851213590102799 0.1046409805230106 0.9166606954369876 1.0 1.0 93 Q12824,O14654,P50213,Q9UI10,P51809,Q96ST3,P40939,Q9Y3A5,O75695,O94906,P51608,P08069,Q15031,Q92620,P31749,Q9UKG1,P36957,P46100,Q6P2Q9,O60333,Q9NW13,Q8NI27 22 +Abnormal blood ion concentration 0.1872751360618232 0.1038456744840166 0.9172918193891512 1.0 1.0 72 Q969N2,Q15056,O43819,O60333,Q99996,P53680,Q10567,Q8NFV4,Q96L73,O43709,Q9NP81,O75962,P78347,P55084 14 +Abnormal sclera morphology 0.2363807885682855 0.1031807163157079 0.9178195443667252 1.0 1.0 30 Q969N2,Q9Y2D4,P31749,P62266,P40939,Q9H9E3,P50454,Q03426 8 +Diffuse mesangial sclerosis 0.2435029052204445 0.1025195605277099 0.9183442875935852 1.0 1.0 19 P11047 1 +Finger syndactyly 0.1992873716331219 0.1023269125432212 0.9184971943033178 1.0 1.0 42 Q15022,O60826,Q9NQ48,Q15427,P48651,P31749,Q96L73,Q05086,Q9UBC2 9 +Abnormal glomerular mesangium morphology 0.2432903379707554 0.1020672103022793 0.9187033274436862 1.0 1.0 20 P11047 1 +Abnormal elasticity of skin 0.1764167200304607 0.1014350169902915 0.9192051402764588 1.0 1.0 65 Q15022,Q15056,P48651,Q9Y2D4,Q8NFV4,Q96L73,Q9Y3D3,Q9BZK7,O43709,O60832,O75787 11 +Unilateral primary pulmonary dysgenesis 0.5809466385287828 0.1007386625571928 0.9197579191897458 1.0 1.0 2 Q96DF8 1 +Pulmonary artery atresia 0.5809466385287828 0.1007386625571928 0.9197579191897458 1.0 1.0 2 Q96DF8 1 +Right aortic arch with mirror image branching 0.5809466385287828 0.1007386625571928 0.9197579191897458 1.0 1.0 2 Q96DF8 1 +Double aortic arch 0.5809466385287828 0.1007386625571928 0.9197579191897458 1.0 1.0 2 Q96DF8 1 +Abnormality of bone marrow cell morphology 0.1698539289856844 0.1006488129022222 0.919829246323014 1.0 1.0 58 P05165,P26440,O95394,O60934,Q9BZK7,Q9H078,Q9Y2R9,O60832 8 +Facial asymmetry 0.2189938841666965 0.0987531922056141 0.9213342339598678 1.0 1.0 35 P31749,O75962 2 +Tented upper lip vermilion 0.2371598233539332 0.0983234639709327 0.9216754468982744 1.0 1.0 25 Q969N2,P46100,P60953,O60762 4 +Complete duplication of phalanx of hand 0.2942952007244219 0.0981607286213336 0.9218046658351344 1.0 1.0 6 P41227,P34897,Q6W2J9,Q9BXW9,O15360 5 +Central sleep apnea 0.2799611784920134 0.0978040021699866 0.9220879293508926 1.0 1.0 7 Q969N2 1 +Hypoplasia of the pons 0.2377563778888723 0.0974068806605787 0.9224032807382893 1.0 1.0 22 Q9Y3C6,Q96S52,Q99986 3 +Generalized hirsutism 0.2345009996140674 0.0970453171002862 0.9226904064198418 1.0 1.0 26 P12955,Q15555,Q9NP72,Q9NQ48,P31749,Q6NUK1,O60216,Q9H2M9,Q06136,Q9P2R7,Q14683 11 +Muscle fiber necrosis 0.5770274344286932 0.0967245147639815 0.922945171141314 1.0 1.0 2 O60231 1 +Abnormal pons morphology 0.2319498732385493 0.0960744941572882 0.923461408296348 1.0 1.0 27 O60762,Q9Y3C6,Q96S52,Q99986 4 +Nail dysplasia 0.2264776095899218 0.0956834907854516 0.9237719531769768 1.0 1.0 30 O60762,Q15022,Q99575,P48651,P10321,Q96L73,O60568,O60832 8 +Cochlear malformation 0.5755200482363494 0.0952158918129161 0.9241433474945652 1.0 1.0 2 Q6ZRS2 1 +Small anterior fontanelle 0.5755200482363494 0.0952158918129161 0.9241433474945652 1.0 1.0 2 P26640 1 +Pancytopenia 0.1945968182800672 0.0946596819806312 0.9245851432405618 1.0 1.0 40 P05165,P26440,O60934,Q9BZK7,Q9Y2R9,O60832 6 +Trismus 0.3299576804203689 0.0938395581371345 0.9252366074644756 1.0 1.0 4 Q15427 1 +Abnormal uterus morphology 0.2143807376813004 0.0926372186953169 0.9261917746245156 1.0 1.0 33 Q86W42 1 +Abnormal vagina morphology 0.2278015785314794 0.0903493622902065 0.9280095950800148 1.0 1.0 22 O43683,O15160,O94761,P36776,Q9UBM7,Q15058,P51809,Q9H9Y6,Q13428 9 +Eczema 0.1876666641566597 0.0903129924964462 0.9280384958250596 1.0 1.0 39 P12955,P05165,Q9Y6X9,P29992,P22830,P11586,Q9HCC0,Q5F1R6,Q9UBM7,P29401,O95394,Q8TAQ2,P61011,Q9Y5S9,P38646,Q9Y3A5,Q8ND04 17 +Hypermethioninemia 0.3008449004224427 0.090129254855927 0.9281845018070976 1.0 1.0 5 P16930,P23526,Q9UJS0,P55263 4 +Multiple renal cysts 0.2265193085583529 0.0893022826420693 0.92884168003382 1.0 1.0 18 Q8NFV4,Q15056,O43709 3 +Sleep wake cycle disturbance 0.2883465472982868 0.0889602676857395 0.9291134866703769 1.0 1.0 6 Q05086,Q9UBM7 2 +Abnormal vitreous humor morphology 0.2570468158500794 0.0884536904899003 0.9295160896423372 1.0 1.0 8 P04439,P53701,P29992 3 +Hypotelorism 0.1970545989575245 0.088043697164447 0.9298419456549214 1.0 1.0 35 Q8TD30,O75175 2 +Pseudobulbar paralysis 0.2726449275362292 0.0874950672404749 0.9302780061682544 1.0 1.0 7 P54136,O94979,P54886,Q15233,P20700,Q14203 6 +Abnormal circulating free fatty acid concentration 0.3249756585064688 0.0873841835744372 0.9303661409629826 1.0 1.0 4 P40939 1 +Abnormal circulating aromatic amino acid concentration 0.2866688162088592 0.0864797821112308 0.9310850273909972 1.0 1.0 6 P16930,P09417,P35270 3 +Ecchymosis 0.2192829711848199 0.0862855108462733 0.9312394561866209 1.0 1.0 14 P38435,Q9BZK7,Q9Y3A5 3 +Abnormal venous morphology 0.2093864110400108 0.0859486456821884 0.931507240889662 1.0 1.0 29 P31749 1 +Decreased adipose tissue 0.219366657184374 0.0853765018980384 0.9319620737111918 1.0 1.0 16 P54132,O75431,Q6NUK1,Q9NW13,P36543,P08069 6 +Hydroureter 0.2182203389830439 0.0850789219091677 0.932198647419226 1.0 1.0 15 Q969N2,P41227,Q9NPD8,Q6W2J9,P36776,Q9UQE7,Q7LGA3,Q16531,Q9BXW9,P21333,Q9NVI1,O15360,O76024,Q9BU61 14 +Long thorax 0.3624849215922834 0.0843798499010098 0.9327544275932508 1.0 1.0 3 P17612,Q6W2J9 2 +Juvenile aseptic necrosis 0.2963186481593193 0.0839511492275371 0.933095271857084 1.0 1.0 5 Q9Y619,Q9NUQ7,Q6ZRS2,Q8IWS0 4 +Impaired distal tactile sensation 0.3221719457013595 0.0839092352595211 0.9331285967830872 1.0 1.0 4 Q5TAQ9,O15269,Q6DD88 3 +Distal sensory loss of all modalities 0.3221719457013595 0.0839092352595211 0.9331285967830872 1.0 1.0 4 O15269,P19367,P48643 3 +Simplified gyral pattern 0.1948680757653609 0.0833535501888231 0.9335704215037416 1.0 1.0 31 Q12824,Q86XL3,Q9NPF4 3 +Abnormal growth hormone level 0.2038325547302742 0.0832270843047509 0.9336709772827844 1.0 1.0 28 Q12824,P31749,Q96ST3,Q8NI27,Q9Y3A5 5 +Abnormal epidermal morphology 0.2140284433698716 0.0828144884233104 0.9339990486059584 1.0 1.0 21 O15446,P31749,Q06136,P78536,P14923 5 +Gastroparesis 0.2684178743961322 0.0819865075475419 0.9346574427500484 1.0 1.0 7 Q99497,P12235,P19525,Q7LG56,P18583,Q96RR1 6 +Glomerular sclerosis 0.1565661570572759 0.0805053158877356 0.9358353684931198 1.0 1.0 33 P36957,P31040,Q96AX1,Q0IIM8,O60333,Q02978,Q12769,P16930,P03915,Q14C86,Q9NPF4 11 +Hypoamylasemia 0.2924990205319472 0.0789989498870109 0.9370334583232304 1.0 1.0 5 Q9Y3A5 1 +Vertigo 0.1877781168925771 0.0788235195382106 0.9371729963623284 1.0 1.0 27 P36957,P31040,O60333,Q02978,Q9BZK7,Q92947,Q03426,O00567,P14923,P06748 10 +Ankylosis 0.2921143541085854 0.0785133448649588 0.9374197153243252 1.0 1.0 5 P48651 1 +Female reproductive system neoplasm 0.2016267542781392 0.0783220122731671 0.9375719079833252 1.0 1.0 21 P60866,O43683,Q07812,P31749,P28340,P35222 6 +Cervical kyphosis 0.5565269822128328 0.0778439289362205 0.9379522022066796 1.0 1.0 2 O75369 1 +Abnormal cervical curvature 0.5565269822128328 0.0778439289362205 0.9379522022066796 1.0 1.0 2 O75369 1 +Bile duct proliferation 0.3561519903498271 0.0775857013459512 0.9381576167658964 1.0 1.0 3 Q5XKP0,P51659 2 +Spina bifida occulta 0.2015714681078411 0.0775670196443019 0.9381724778222656 1.0 1.0 19 Q8NFV4,Q15056,O43709 3 +Cervical ribs 0.3555488540410195 0.076963939365056 0.9386522320638432 1.0 1.0 3 Q9Y5S9,P18583 2 +Abnormality of vitamin e metabolism 0.2900410606171477 0.07593700599659 0.93946921531508 1.0 1.0 5 Q9Y3A5 1 +Abnormal ureter morphology 0.1505472007306726 0.0758946425174464 0.9395029192195812 1.0 1.0 27 Q969N2 1 +Missing ribs 0.1949647445341502 0.075104846795738 0.9401312915337148 1.0 1.0 11 Q06124,O60826,Q6ZRS2,P39019 4 +Severe short limb dwarfism 0.352417684696293 0.0738057949706159 0.9411649158846268 1.0 1.0 3 O75369 1 +Noncompaction cardiomyopathy 0.3523655048142411 0.0737541504450961 0.9412060102535578 1.0 1.0 3 Q15233 1 +Lipoatrophy 0.1648248156702486 0.0736690713349164 0.9412737093936374 1.0 1.0 23 Q14126,P40123,P15924,Q6NUK1,Q9NW13 5 +Hypomimic face 0.189546549315524 0.0730308567726773 0.9417815629103754 1.0 1.0 11 Q7LG56,Q96QK1,O75787 3 +Ureteropelvic junction obstruction 0.3106907009277539 0.070838528605337 0.943526267440106 1.0 1.0 4 Q96L73 1 +Abnormal arachnoid mater morphology 0.2154078549848881 0.0697621020728583 0.9443830118191718 1.0 1.0 9 O43776,Q9NQH7,Q14738,Q15904,Q9NZJ4,Q14697,P18583,Q9UHX1 8 +Abnormality of neutrophil physiology 0.2844571219151859 0.0693382293094421 0.9447203963601732 1.0 1.0 5 Q9Y3A5 1 +Vitritis 0.3473307844622162 0.0689210151755972 0.9450524906015544 1.0 1.0 3 P04439 1 +Reduction of neutrophil motility 0.3078008208117339 0.0678351318000801 0.945916877029764 1.0 1.0 4 Q9Y3A5 1 +Deformed rib cage 0.3078008208117339 0.0678351318000801 0.945916877029764 1.0 1.0 4 Q9Y3A5 1 +Prominent superficial blood vessels 0.1648721338990776 0.0678013395915584 0.94594377737847 1.0 1.0 13 Q9H9E3,Q6NUK1,P48651,P32322 4 +Sideroblastic anemia 0.1367211131276408 0.0657610272913139 0.947568084756376 1.0 1.0 13 Q9NVI1,P38398,Q15031,Q9NPD8,Q9H1K1,Q9BXW9,Q9NVS9,O76024,O15360,Q9Y2Z4,P38646,Q9Y606 12 +Glycosuria 0.2339317286080208 0.0655010217359466 0.9477750928571028 1.0 1.0 8 P38117,Q9UKG1 2 +Generalized aminoaciduria 0.304754823527431 0.0647908254996738 0.948340546293575 1.0 1.0 4 P38117 1 +Streak ovary 0.2529721016370789 0.0645260513282505 0.948551364370516 1.0 1.0 7 O75616 1 +Short tibia 0.5357250527585051 0.0621197837715978 0.9504674422515094 1.0 1.0 2 O75369 1 +Abnormality of macular pigmentation 0.3395657418576671 0.0620363224917064 0.9505339065284965 1.0 1.0 3 Q9UM00,P55265 2 +Esophagitis 0.2271079031253062 0.0603841944698848 0.9518496466710308 1.0 1.0 8 O95394 1 +Abnormality of cartilage of external ear 0.5296955079891349 0.058164073876286 0.9536179371469652 1.0 1.0 2 P08754 1 +Abnormality of the crus of the helix 0.5296955079891349 0.058164073876286 0.9536179371469652 1.0 1.0 2 P08754 1 +Hyperglycemia 0.2457729468599007 0.0577431206380229 0.9539532456741922 1.0 1.0 7 P02545,Q9UKG1,P24752,P42704,P40763,P35610 6 +Insulin resistant diabetes mellitus 0.2457729468599004 0.0577431206380226 0.9539532456741924 1.0 1.0 7 P02545,O75431,Q96MF7,A5YKK6,P40763,Q9UKG1 6 +Persistence of primary teeth 0.2457729468599004 0.0577431206380226 0.9539532456741924 1.0 1.0 7 Q6W2J9,P02545,P61586,P21333,Q6ZRS2,P40763 6 +Increased urine proteinogenic amino acid derivative level 0.5260777811275159 0.0559136658355513 0.9554105840992896 1.0 1.0 2 P48637 1 +Woolly hair 0.270282012664054 0.0547340619843906 0.9563503324865764 1.0 1.0 5 P14923 1 +Abnormality of the brainstem white matter 0.2917043740573174 0.0531083086846831 0.9576456114242592 1.0 1.0 4 P36405,P20700,Q9NZJ4 3 +Abnormality of taste sensation 0.5200482363581422 0.0523618016841217 0.9582404101819444 1.0 1.0 2 Q9H4A3 1 +Decreased corneal reflex 0.5200482363581422 0.0523618016841217 0.9582404101819444 1.0 1.0 2 Q9H4A3 1 +Spastic dysarthria 0.2118422537200728 0.0512831650038761 0.9590998828321388 1.0 1.0 8 Q8WVX9,O94905,Q9H2M9,Q9Y4W6 4 +Increased hepatic glycogen content 0.3253920386007318 0.051162373269674 0.9591961343380032 1.0 1.0 3 P31040,P36871 2 +Hypoglycemic coma 0.2065841135608591 0.048817158801956 0.9610650077308074 1.0 1.0 8 P00367,Q16836,P38117,P35914,Q13423,P40939,P13804 7 +Nocturnal seizures 0.5134157371118357 0.0487322268072114 0.9611326930994568 1.0 1.0 2 Q9NQX3 1 +Atopic dermatitis 0.2630052387333379 0.0483707756348874 0.9614207496971574 1.0 1.0 5 O95394 1 +Chorioretinal hypopigmentation 0.3208685162846937 0.0481266657746002 0.9616152946091509 1.0 1.0 3 Q9Y619,Q96AX1 2 +Acantholysis 0.2829323104696417 0.0464314258657033 0.9629663892970386 1.0 1.0 4 P14923,P15924 2 +Natal tooth 0.2300724637681131 0.045657390848179 0.9635833255454844 1.0 1.0 7 O75844,P02545,P21333,O14802,P15924,P14923 6 +Alveolar ridge overgrowth 0.5067832378655275 0.0453811982436755 0.9638034671741396 1.0 1.0 2 P98175 1 +Hypoplasia of the fovea 0.505275851673185 0.0446571294846924 0.9643806052986984 1.0 1.0 2 Q9Y6K9 1 +Abnormal fallopian tube morphology 0.1921290787144071 0.0435223027382939 0.9652851863539872 1.0 1.0 8 O60934 1 +Subcortical cerebral atrophy 0.3107026221743154 0.0420184597127202 0.9664839823894036 1.0 1.0 3 Q92947 1 +Secundum atrial septal defect 0.3103136308805876 0.0418035615020319 0.9666552958285974 1.0 1.0 3 P34897,A1X283 2 +Abnormality of vitamin a metabolism 0.246077078191889 0.0408791288053657 0.967392256337271 1.0 1.0 6 Q9Y3A5 1 +Calcinosis 0.2456987624509536 0.040574495758753 0.9676351168442808 1.0 1.0 6 O94761,Q14739,P02545,Q9H1A4,P57678 5 +Oromotor apraxia 0.2715413473581952 0.0390585096621928 0.9688437402017922 1.0 1.0 4 P39656 1 +Avascular necrosis of the capital femoral epiphysis 0.2961399276236522 0.0348513520312646 0.9721982724789786 1.0 1.0 3 Q9NUQ7,Q6ZRS2 2 +Connective tissue nevi 0.2940289505428306 0.0339543018543884 0.972913591506599 1.0 1.0 3 Q6NUK1,P49815 2 +Gingivitis 0.2567119155354472 0.0314357403093863 0.9749220385820994 1.0 1.0 4 P40763,P61011,Q01968 3 +Absent sternal ossification 0.4606572203798461 0.0287120251709748 0.9770942656229652 1.0 1.0 2 Q9Y619 1 +Cellulitis 0.242533936651586 0.0259544588107682 0.9792936628055476 1.0 1.0 4 P02545,P40763,P61011 3 +Dilation of virchow robin spaces 0.4449804039794814 0.0251977864333394 0.9798972025672444 1.0 1.0 2 P27635 1 +Patellar hypoplasia 0.4338257461561511 0.0232062515692206 0.981485751920406 1.0 1.0 2 O94761 1 +Abnormality of ulnar metaphysis 0.4338257461561511 0.0232062515692206 0.981485751920406 1.0 1.0 2 O94761 1 +Extrapyramidal dyskinesia 0.4314139282484097 0.0228249504099534 0.9817899056580526 1.0 1.0 2 P24752 1 +Acromesomelia 0.422369611094355 0.0215364814786653 0.982817702193416 1.0 1.0 2 Q9NS87 1 +Stereotypical body rocking 0.4154356346095829 0.0206876850010044 0.983494792864622 1.0 1.0 2 Q9NS87 1 +Abnormal circulating glutamine concentration 0.4136267711787723 0.0204844844588462 0.983656889088912 1.0 1.0 2 P37837 1 +Delirium 0.4136267711787723 0.0204844844588462 0.983656889088912 1.0 1.0 2 P26358 1 +Abnormal circulating arginine concentration 0.413626771178772 0.0204844844588462 0.983656889088912 1.0 1.0 2 Q9NVS9 1 +Blistering by anatomical location 0.372625866747058 0.0174573296340061 0.986071773673004 1.0 1.0 2 Q9H4L7 1 +Acral blistering 0.372625866747058 0.0174573296340061 0.986071773673004 1.0 1.0 2 Q9H4L7 1 +Congenital blindness 0.3367500753693115 0.0164051951232358 0.9869111351988072 1.0 1.0 2 Q96MF7 1 +Abnormality of blood volume homeostasis 0.335845643653905 0.0163897485716703 0.9869234581070336 1.0 1.0 2 P31153 1 +Shagreen patch 0.320771781730481 0.0161851608872767 0.9870866738109938 1.0 1.0 2 Q6NUK1 1 +Abnormality of the subungual region 0.3207717817304827 0.0161851608872767 0.9870866738109938 1.0 1.0 2 P16615 1 +Food intolerance 0.2960506481760698 0.0160041788749698 0.9872310578624816 1.0 1.0 2 Q6ZRS2 1 +Thoracolumbar scoliosis 0.19770600664051 0.0158223255744632 0.9873761374325584 1.0 1.0 6 Q99575,P36776,P27635,P78318,Q93008 5 +Ridged nail 0.1898906658383146 0.0138420059173978 0.9889560298619482 1.0 1.0 6 O60832,P16615 2 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..eada9e941fdc830fd88e4ffc5bc8a3e79148a33e --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lacrimal punctum morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 2nd finger", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal interphalangeal creases", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent lacrimal punctum", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent phalangeal crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Acute rhabdomyolysis", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bicoronal synostosis", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal symphalangism", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged interphalangeal joints", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid apraxia", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Helicobacter pylori infection", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent macular lesion", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hypereosinophilia", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hematocrit", "Increased hemoglobin", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Increased vldl cholesterol concentration", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Interlobular septal thickening", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intervertebral space narrowing", "Intestinal atresia", "Intestinal bleeding", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "Ivory epiphyses", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphadenitis", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Moderately short stature", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuchal rigidity", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary interstitial thickening", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short middle phalanx of the 2nd finger", "Short middle phalanx of toe", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short term memory impairment", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supernumerary vertebrae", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Underfolded helix", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABHD11", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT1", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG13", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARMC9", "ARPC1B", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATP13A2", "ATP1A1", "ATP2A2", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATRX", "ATXN10", "ATXN2", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCOR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "C21orf59", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CAP2", "CAPN1", "CARS", "CASK", "CAST", "CBL", "CCDC22", "CCDC47", "CCDC88A", "CCT5", "CD2AP", "CD3EAP", "CDC42", "CDC45", "CDC73", "CDH2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CENPE", "CEP250", "CEP55", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHORDC1", "CHP1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "CNOT3", "CNP", "COA3", "COA7", "COASY", "COG2", "COG4", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2B", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB11", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FAH", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNE", "GNPAT", "GNS", "GOT2", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GSDME", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HAX1", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD13", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP2", "IGF2R", "IKBKB", "IKBKG", "IMPA1", "IMPAD1", "IMPDH1", "INF2", "INTS1", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5C", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LSS", "LZTFL1", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAPK1", "MAPRE2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED23", "MFF", "MFN2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOGS", "MORC2", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVK", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NACC1", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NELFA", "NEMF", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NT5C2", "NT5C3A", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PAK1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PCNT", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLCB3", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PSPH", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "QRSL1", "RAB11B", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "RECQL4", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "RRM2B", "RTN2", "SACS", "SAMHD1", "SAR1B", "SARS", "SARS2", "SASS6", "SBDS", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC9A3R1", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SRP54", "SRP72", "SRSF2", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE1", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D2B", "TBC1D8B", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TCOF1", "TDRD7", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIA1", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TKFC", "TKT", "TMCO1", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM43", "TMEM63A", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIO", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMU", "TSC2", "TSFM", "TSPYL1", "TSR2", "TTC19", "TTC37", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXN2", "UBA1", "UBA5", "UBE2T", "UBE3A", "UBE4A", "UBQLN2", "UBR1", "UBTF", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAC14", "VAMP7", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13A", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC5", "WBP11", "WDR1", "WDR26", "WDR36", "WDR4", "WDR45B", "WDR48", "WFS1", "WIPI2", "WNK1", "WRAP53", "XPNPEP3", "XRCC1", "YAP1", "YARS", 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setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Ribosome 54 72 3.201440506695809 0.0013674230946669 37.58980582524272 71.83252427184466 -1.1465156070967828 0.3112763158975234 13.159558265713326 1.6746570252811466 2.1898923040449123 0.3742528198975103 0.3394178268581344 0.1992060977406469 0.0044595287286233 1.1660866218274068e-14 +Melanoma 3 11 2.0126958826188632 0.044146632813208 3.2815533980582523 9.555825242718448 -0.1087353388073535 0.6020729829775038 2.200694840528607 1.8912907311288945 0.7979168715574909 0.2924522472511009 1.0 0.0663348012473392 0.2844746469635782 0.3534364672461926 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..76f456185f6d06478aadee2d3e6827c64efd2275 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 17.727777777777778 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..48d2a1978f8427da6a380f9ceb940b86f506efa4 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3ea9839b1fa93885197e7d583bc2ecf08d59375e --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,68 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosome 0.5832790797491011 3.201440506695809 0.0013674230946669 0.2183159097678163 0.1230680785200278 72 P83731,Q02878,P62424,P18077,P62269,Q9Y3U8,P61513,P50914,P62841,P62750,P62280,P62701,P62857,Q9UHA3,P39019,P08708,P05388,P30050,P62277,P46777,P40429,P61927,P62241,P62854,P62753,P62266,P62851,P62081,P46776,Q02543,P26373,P63173,P61247,P61353,P36578,P62861,P62910,P62847,P18124,P83881,P62899,P15880,P84098,P39023,P60866,P62917,P32969,P47914,P25398,P46781,P46778,P61254,P61313,P62244 54 +Melanoma 0.6767876260793808 2.0126958826188632 0.044146632813208 0.9997045871456534 0.6704408382175311 11 P31749,Q9NWH9,P42771 3 +Basal transcription factors 0.7903415414602577 1.6811186293166631 0.0927398745581702 0.9999999753550304 0.6955490591862767 4 Q00403,P13984 2 +Fc epsilon ri signaling pathway 0.5943865984769433 1.5877709389489736 0.1123381451807694 0.9999999995163176 0.7645663617490625 10 P31749,P46734 2 +Cell adhesion molecules cams 0.5924221327207403 1.5774807229360934 0.1146849542623593 0.9999999996996608 0.7645663617490625 10 P10586,P10321,Q13740,Q9Y624,Q9BY67 5 +Spliceosome 0.4653575109069895 1.4759985909221895 0.1399442705030491 0.9999999999983602 0.8187293276600933 102 Q9NW64,Q5VTL8,P09234,Q86V81,P55769,P09012,Q13247,O95391,Q15428,P08621,Q13595,O94906,P52272,Q9ULR0,Q9BWJ5,Q9UNP9,Q92620,P17066,P62314,P08579,P62312,Q9BZJ0,Q9Y3C6,Q96DI7,Q15427,Q8WYA6,Q86XP3,Q8NI27 28 +Notch signaling pathway 0.6160672814015166 1.4516267557902407 0.1466054150568612 0.9999999999995954 0.8187293276600933 8 O14641 1 +Homologous recombination 0.5642311125758499 1.4198844213423938 0.1556413320278604 0.9999999999999404 0.8187293276600933 12 P46100,P54132,Q9Y2S7 3 +Rna polymerase 0.5631080382067623 1.411698418591682 0.1580387792014774 0.9999999999999644 0.8187293276600933 13 P62875,Q9GZS1,O15160,P19388,P24928,O95602,P62487,Q9H9Y6 8 +Vegf signaling pathway 0.5541511344373421 1.363445646541478 0.1727421034428784 0.9999999999999986 0.8187293276600933 13 Q99653,P31749,P60953 3 +N glycan biosynthesis 0.5404072003973752 1.3004104480056276 0.1934603309058924 1.0 0.8187293276600933 18 O60762,Q16706,O75340,P04844,Q9Y673,Q9BT22,P39656,Q13724,P46977 9 +Oxidative phosphorylation 0.3702452887716106 1.2343475548860767 0.2170734226423365 1.0 0.8682936905693461 63 O14548,P20674,P56134,P21283,O75438,O43676,P19404,P09669,Q86Y39,O95139,O95168,O75380,P28331,Q9H2U2,Q9Y5K8,P03915,Q9UDW1,O14949 18 +Phenylalanine metabolism 0.6677927727377742 1.179945957149026 0.2380217098556065 1.0 0.8925814119585246 4 P14174 1 +Parkinsons disease 0.3456291030310328 1.079981404365152 0.2801504610270116 1.0 0.9730995965628902 58 O14548,P20674,P05141,P19404,P09669,O75438,O43676,P42574,O95139,P48047,O95168,O75380,P28331,P08574,P03915,Q9UDW1,O14949 17 +Huntingtons disease 0.3768293694841426 0.9596684031058802 0.337222130460431 1.0 1.0 82 P05141,Q92769,O75438,O43676,P42574,P24928,P48047,Q96ST3,O94973,Q9UDW1,P19387,P19404,P09669,P42858,P28331,P14927,O14548,P20674,P62875,Q07812,Q01970,P53680,O75380,P08574,O75489,O95782,O95139,P19388,O95168,P04179,P47985,P62487,Q00059,Q16795,O14949 35 +Alzheimers disease 0.3420057922006416 0.8993538727470015 0.368464200528972 1.0 1.0 66 O75438,O43676,P42574,P48047,Q9UDW1,P19404,P09669,Q99653,P28331,O14548,P20674,P17655,Q9UHD1,Q01970,O75380,P08574,P78536,O95139,O95168,Q16795,O14949 21 +Non small cell lung cancer 0.4611329846462326 0.875619240197131 0.3812370622099665 1.0 1.0 12 P31749 1 +Amyotrophic lateral sclerosis als 0.4559644171857134 0.8353103745755452 0.4035429775953654 1.0 1.0 15 P42574,Q9UHD1,Q99653,Q16539,P20339,Q9BUN8,P46734 7 +Valine leucine and isoleucine biosynthesis 0.4639711541475083 0.8119802400341798 0.4168029699775926 1.0 1.0 9 Q15031,O15382,Q5ST30,P41252,P08559,P11177 6 +Tyrosine metabolism 0.4264197909571444 0.7198408586755145 0.4716229848865474 1.0 1.0 10 P14174,O43709 2 +Insulin signaling pathway 0.3397154742916371 0.7134443437325423 0.4755708415352333 1.0 1.0 43 P41440,Q15382,P10586 3 +Gnrh signaling pathway 0.4223836644054914 0.6707638810413666 0.5023709603139146 1.0 1.0 14 P60953,P46734 2 +Pentose and glucuronate interconversions 0.4972842486421183 0.6604812427586733 0.5089450516300398 1.0 1.0 5 Q16851,O60701,P15121,Q7Z4W1 4 +Small cell lung cancer 0.4028373634395443 0.591269602853493 0.554339793179782 1.0 1.0 12 P11047 1 +Focal adhesion 0.3263741462228719 0.5265556322909151 0.5985022093567174 1.0 1.0 41 P11047,P17655,Q9NWH9,P31749,P60953 5 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.4567930020104576 0.5044319998903556 0.6139578358627649 1.0 1.0 5 Q96S52 1 +Systemic lupus erythematosus 0.3744903889065237 0.4603099415210127 0.6452937663572631 1.0 1.0 13 Q9P0M6,P62805,P62314 3 +Selenoamino acid metabolism 0.3705964013930217 0.4511687737203261 0.6518679134715146 1.0 1.0 12 Q9NZL9 1 +Alanine aspartate and glutamate metabolism 0.3740470478390492 0.4477983298560376 0.6542987488712093 1.0 1.0 15 Q8TD30,P30038 2 +Fc gamma r mediated phagocytosis 0.3655814386756397 0.4285356547584539 0.6682611808032881 1.0 1.0 26 P62330,O15144,P31749,P78356,P60953 5 +Abc transporters 0.4053947582085186 0.3288402594073392 0.7422764311912196 1.0 1.0 5 O15439 1 +Epithelial cell signaling in helicobacter pylori infection 0.3381488274036056 0.322593887862477 0.747002823237038 1.0 1.0 27 P42574,Q9NWH9,Q16539,Q9Y624,P60953,Q9Y5K8,P78536 7 +Adherens junction 0.3409404387106672 0.3220591461002646 0.7474078873620011 1.0 1.0 25 Q9NWH9,P10586 2 +Colorectal cancer 0.3412544395543757 0.3163803026900412 0.7517138658856111 1.0 1.0 17 P42574,P31749,P61586,Q07812 4 +Glycine serine and threonine metabolism 0.3365286620176452 0.2887709021878508 0.7727567006079017 1.0 1.0 9 P78330,Q9Y617,P34896,P09622 4 +Viral myocarditis 0.3209421910375595 0.2791267271655772 0.7801475726292824 1.0 1.0 11 P42574,P10321 2 +Mtor signaling pathway 0.3274249969822453 0.2741204416279048 0.7839920651487999 1.0 1.0 16 Q15382 1 +Renal cell carcinoma 0.3245583298059113 0.2582220897666523 0.7962355107146135 1.0 1.0 20 P31749,Q9NWH9 2 +Rna degradation 0.2923548644400805 0.2570587067440179 0.7971334538527892 1.0 1.0 37 O75175,Q8TCS8,Q13868,Q99547,P62312 5 +Regulation of actin cytoskeleton 0.2378433078472964 0.2557513298297998 0.7981428573790881 1.0 1.0 55 Q8N8S7,P62140,P35080,O15144,Q13576,P60953,P78356 7 +Apoptosis 0.317859146913694 0.2389507856632574 0.8111437446931657 1.0 1.0 22 P31749,O94919,P17655 3 +Primary bile acid biosynthesis 0.6744045824540256 0.2378459858595317 0.8120005503562271 1.0 1.0 2 P22307 1 +Glioma 0.3100578303522875 0.2274247418362525 0.820093483084416 1.0 1.0 15 P31749,P42771 2 +Cardiac muscle contraction 0.3072312013945192 0.2100162567039822 0.8336549849634036 1.0 1.0 22 O14548,P20674,P09669,P54709,P08574,Q9UDW1,O14949 7 +Citrate cycle tca cycle 0.3012737781026059 0.1991586173897842 0.8421386694581321 1.0 1.0 25 P36957,P31040,P10515,P09622,P50213,Q02218,P11498,P08559,P11177,Q96I99,Q99798,Q9P2R7,O75390 13 +Glyoxylate and dicarboxylate metabolism 0.2859404395403446 0.1910770395038741 0.8484652360251168 1.0 1.0 10 Q6UB35,Q99798 2 +Proximal tubule bicarbonate reclamation 0.3119747268661957 0.1843593834938029 0.8537315309001503 1.0 1.0 8 P00367,Q16822,P05023,Q9UBX3,P54709 5 +Tight junction 0.2652393892703238 0.1839219097831341 0.8540747164851119 1.0 1.0 38 P31749,Q9Y624,P60953,P51153 4 +Axon guidance 0.2874537274187846 0.1696038652065569 0.8653216825981407 1.0 1.0 26 Q9Y281,Q99653,Q9UHD1,Q9NWH9,P61586,P60953,O94813,Q9BPU6 8 +Aldosterone regulated sodium reabsorption 0.3157700852769725 0.1630627599363722 0.8704690205641805 1.0 1.0 7 P54709 1 +Aminoacyl trna biosynthesis 0.2671655205009519 0.148841770051382 0.8816784899890162 1.0 1.0 32 Q5T160,Q9BW92,Q15031,Q5ST30,Q5JTZ9,Q9Y285,Q9NP81,Q9UGM6 8 +Phosphatidylinositol signaling system 0.27266855377581 0.1480957191091923 0.8822672278492787 1.0 1.0 14 Q9UBF8,P78356,Q01970 3 +Hedgehog signaling pathway 0.4034981905910794 0.140719519064064 0.888091524551615 1.0 1.0 3 P17612,P49841 2 +Nucleotide excision repair 0.2697949579496908 0.1358266584906481 0.8919583159308426 1.0 1.0 25 P41440 1 +Autoimmune thyroid disease 0.3510648083218063 0.1252737253605827 0.9003068524225513 1.0 1.0 4 P10321 1 +Allograft rejection 0.3510648083218063 0.1252737253605827 0.9003068524225513 1.0 1.0 4 P10321 1 +Graft versus host disease 0.3510648083218063 0.1252737253605827 0.9003068524225513 1.0 1.0 4 P10321 1 +P53 signaling pathway 0.2556331556662851 0.1183769965903505 0.9057689516705976 1.0 1.0 16 P42574,P42771,Q7LG56 3 +Cysteine and methionine metabolism 0.24678353060514 0.1079569593982564 0.9140298340251783 1.0 1.0 16 P25325,Q9NZL9 2 +Inositol phosphate metabolism 0.2404065814900904 0.1024878959953098 0.9183694198551702 1.0 1.0 15 P78356,Q01970,Q9UBF8 3 +Snare interactions in vesicular transport 0.2302658351533284 0.0955085161348745 0.9239109262864986 1.0 1.0 13 O75396,Q9UNK0,Q86Y82,P51809,O15400 5 +Protein export 0.2313624538086458 0.0943489002869977 0.9248320063150977 1.0 1.0 15 P08240,O76094,P37108,P61011,Q9Y5M8,P09132,P60468,Q15005 8 +Type i diabetes mellitus 0.2944612036513002 0.0815132897851088 0.9350337563293658 1.0 1.0 5 P10321 1 +Steroid hormone biosynthesis 0.5538136870666177 0.0756030578377075 0.9397349036269562 1.0 1.0 2 P21964 1 +Ether lipid metabolism 0.2857573928786898 0.0708309508072035 0.9435322984986458 1.0 1.0 5 O00116,P43034,Q15102,Q8NF37 4 +Starch and sucrose metabolism 0.1617835097759124 0.0679321430387233 0.9458396514005216 1.0 1.0 14 P52789,Q04446 2 +Olfactory transduction 0.3050293318132726 0.0390154089067 0.9688781034363838 1.0 1.0 3 Q13555 1 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0f85f7e4ee8884bdc3faabf41f744e92916a266d --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEX1", "APPL1", "APRT", "AQR", "ARF6", "ARFGAP1", "ARFGAP3", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "B3GALT6", "B4GALT1", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BDH2", "BIRC6", "BLM", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BRCA1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CASP3", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CD47", "CDC23", "CDC25C", "CDC27", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHORDC1", "CHP1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT3", "CNOT7", "CNOT9", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNM1L", "DNM2", "DNMT1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHMT2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAH", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLM", "GFPT1", "GGA1", "GGCT", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTSE1", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HCCS", "HDAC1", "HDAC2", "HERC4", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGF1R", "IGF2BP1", "IGF2R", "IKBKB", "IKBKG", "ILK", "IMPA1", "IMPDH1", "IMPDH2", "INPP4A", "IQGAP1", "IQGAP2", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KDELR1", "KDSR", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LSM2", "LSM6", "LSS", "LTA4H", "LYPLA1", "M6PR", "MAD1L1", "MAGED1", "MAN1A2", "MAN2A1", "MAN2B1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME2", "MGAT1", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPST", "MRE11", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTOR", "MTR", "MUT", "MVK", "MYH10", "MYH14", "MYH9", "MYL6", "NAA16", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCKAP1", "NCL", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NFKB1", "NIT2", "NLN", "NME1", "NME2", "NME3", "NNT", "NPC1", "NPC2", "NSD1", "NSD2", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NUDT12", "NUDT5", "NUDT9", "OAT", "OCRL", "OGDH", "ORC3", "ORC5", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PECR", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PI4KB", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIP4K2B", "PISD", "PKM", "PKN1", "PLA2G15", "PLCB3", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "PPA1", "PPA2", "PPAT", "PPID", "PPIE", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTDSS1", "PTGES2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB11B", "RAB13", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RABEP1", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RALA", "RAPGEF2", "RARS", "RARS2", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RDH11", "RDX", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RIPK1", "RNASEH2A", "RNASEH2B", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRM1", "RRM2", "RRM2B", "RSL24D1", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SETD7", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC38A2", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SORT1", "SPCS2", "SPHK2", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SYMPK", "TAB1", "TALDO1", "TAP1", "TARS", "TARS2", "TARSL2", "TBK1", "TBL1XR1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TMLHE", "TOLLIP", "TOMM40", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSC2", "TSG101", "TSPO", "TTC37", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UCK2", "UGCG", "UGDH", "UGP2", "UMPS", "UNC45A", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USP39", "VAMP7", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VTA1", "VTI1B", "WARS", "WARS2", "WASL", "WBP11", "WDR61", "XAB2", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX3", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["AARS2", "ABCC4", "ACO2", "ADAM17", "AGPS", "AKR1B1", "AKT1", "ALCAM", "ALDH4A1", "ALG1", "ALG5", "ALYREF", "AP2A1", "AP2A2", "AP2S1", "ARF6", "ARPC2", "ATP1A1", "ATP1B3", "ATP5J2", "ATP5O", "ATP6V1C1", "ATP6V1D", "ATRX", "BAX", "BCAT2", "BLM", "BUD23", "CADM1", "CAMK2G", "CAPN2", "CASP3", "CDC42", "CDKN2A", "CFL2", "CHORDC1", "CHP1", "CNOT3", "COMT", "COX5A", "COX6C", "COX7A2L", "CRNKL1", "CS", "CTNNBL1", "CYC1", "DCXR", "DDOST", "DDX42", "DERL1", "DHX38", "DLAT", "DLD", "DLST", "DPM1", "DPYSL5", "DVL2", "ENAH", "ENDOD1", "EXOSC2", "F11R", "FARSA", "FAU", "GBE1", "GLUD1", "GPT2", "GSK3B", "GTF2B", "GTF2F2", "H2AFY2", "H4C1*", "HDAC2", "HK2", "HLA-C", "HNRNPM", "HSPA6", "HTT", "IARS", "IDH3A", "IQGAP2", "ISY1", "LAMC1", "LARS2", "LPCAT1", "LSM6", "MAN2A1", "MAP2K3", "MAPK14", "MAT2B", "MIF", "MOGS", "MPHOSPH6", "MPST", "MTHFD1L", "ND5", "NDUFA11", "NDUFA9", "NDUFB1", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFS1", "NDUFS3", "NDUFS6", "NDUFV2", "OGDH", "PAFAH1B1", "PAFAH1B3", "PC", "PCK2", "PDCD6", "PDHA1", "PDHB", "PFN2", "PI4KB", "PIGS", "PIP4K2B", "PLCB3", "PNPT1", "POLDIP2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "PPA2", "PPIE", "PPIL1", "PPP1CB", "PRKACA", "PRPF38B", "PRPF6", "PSAT1", "PSPH", "PTPRF", "RAB13", "RAB5A", 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0.9693069881759844 1.2392371904949704 0.3053089698625158 1.0 0.1375212864755611 0.0053269286919759 0.0005539528919822 +Selenoamino acid metabolism 57 90 2.353023292695801 0.0186214675798859 45.359223300970875 88.94660194174757 -1.2269036973447986 0.3270935993226454 16.116146621354947 1.9650003351851577 2.2110932203759184 0.3833177831487697 0.410668613679594 0.2825796829681516 0.0047173667803823 6.075712505927925e-12 +Defects in biotin btn metabolism 2 6 2.3274066781104628 0.0199436306687434 4.322815533980583 6.684466019417476 -1.956139594978885 0.1020422735751905 1.2148609872736351 0.4647281868794612 1.4379338792361345 0.2253926888686752 1.0 0.0758460972151271 0.0007445311440673 0.0054555274430988 +Rna polymerase ii transcription termination 10 46 2.2863977011931373 0.0222310027017007 17.20873786407767 44.70145631067961 -0.86103981823213 0.4512938122200936 7.0779379202652954 3.184564992246008 1.0646102763598504 0.3419500531624954 0.00029486717559 0.0039428820669095 0.0054413454682795 0.0003267416905072 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 28 51 2.259188129137815 0.0238716849294784 21.27912621359223 50.43446601941748 -0.6423341772855271 0.4501870221883518 8.810973476604579 1.4474874301684992 1.4039245476891489 0.3707470696386276 0.2523879312119707 0.1138374922433585 0.4264687992494925 0.0077406427377309 +Nonsense mediated decay nmd 57 87 2.2152644368735244 0.0267419193257389 42.101941747572816 85.76941747572816 -1.1457400111181046 0.3421409039593034 15.03730946151162 2.536670214507658 2.1258465434199816 0.3829653082446096 0.4193881110516689 0.2934964278814309 0.0183973869425612 7.490549405329115e-11 +Dna damage telomere stress induced senescence 7 15 2.175051715600014 0.0296262411770453 7.546116504854369 16.04854368932039 -1.394865541664342 0.2635542747487542 2.834480734626769 1.897257298786852 1.2566312758742972 0.3207825031697647 1.0 0.3128615540599918 0.0022059328798847 0.0004198862600832 +Biotin transport and metabolism 2 7 2.171904754054073 0.0298628478236033 5.116504854368932 8.03640776699029 -2.0531807267583235 0.1038341457369441 1.4145634399717075 0.9533460280821764 1.4870488903095456 0.2349123521752051 1.0 0.1027954944442906 0.0020770710993276 0.0143992028043342 +Trna modification in the mitochondrion 0 6 2.1433846186582755 0.0320822271488259 2.412621359223301 5.728155339805825 -0.2376870320653928 0.5819983900130897 1.6144480923953328 1.23023539271987 0.7936016480232341 0.2944317395108509 0.0432957136582515 0.0849171013653387 0.200296332152138 0.3641042813337177 +Wnt5a dependent internalization of fzd4 1 8 2.053418791014378 0.0400319783915827 4.094660194174757 8.344660194174757 -0.5762341483776429 0.5285363659595133 2.2519184121582727 1.4919348326003306 0.7270990108390278 0.3040269016227129 0.0619434524836269 0.1203280145079081 0.0390924086837951 0.1310880735395047 +Apoptosis induced dna fragmentation 4 10 1.9987925012819217 0.0456308094805368 4.461165048543689 9.480582524271844 -1.2396777487494677 0.2413940671270342 1.815774087232708 0.7956871918457745 1.1955398659006715 0.28131040332984 1.0 0.1027954944442906 0.0020770710993276 0.0001003925771558 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1e24df670c8b084551b0a63c35f08fcd63fbff3d --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 1407, + "title": "Average number of proteins per term", + "value": 20.009239516702202 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2120e9f86675fdcc113f6e36ee090f13140ac317 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..131cf31b19c52b763714c639eb2787a4991ee55d --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,383 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Rrna modification in the nucleus and cytosol 0.5148907891173746 2.9426074653345125 0.0032546080303654 0.9898135972508676 0.712720308882218 53 P22087,Q9BVJ6,P55769,Q68CQ4,Q92979,Q9H0A0,O00567,Q8TCT8,P46087,Q13601,P62753,P62081,O43709,Q15061,O60832,Q9Y6V7,Q12788,Q9H0S4,O15213,Q9UNQ2,Q9Y2P8,Q14690,P15880,P62263,Q9Y3A2,Q8NI36,Q9NXG2,Q9H583 28 +Eukaryotic translation elongation 0.5616427869297577 2.8935203949632116 0.0038094954968381 0.9953467786639216 0.712720308882218 77 P83731,Q02878,P62424,P61513,P18077,Q9Y3U8,P62269,P50914,P62750,P62701,P62280,P62841,P62857,P39019,P08708,P05388,P30050,P62277,P61927,P46777,P40429,P62241,P62854,P46776,P62081,P62851,P62753,P62266,Q02543,P26373,P63173,P61247,P61353,P36578,P62861,P62910,P62847,P83881,P18124,P62899,P15880,P84098,P39023,P32969,P60866,P62917,P47914,P62263,P25398,P46781,P46778,P61254,P61313,P62244 54 +Response of eif2ak4 gcn2 to amino acid deficiency 0.5599854907274062 2.8775033891833854 0.0040083560448955 0.9964863163810168 0.712720308882218 77 P83731,Q02878,P62424,P61513,P18077,Q9Y3U8,P62269,P50914,P62750,P62701,P62280,P62841,P62857,P20042,P39019,P08708,P05388,P30050,P62277,P61927,P46777,P40429,P62241,P62854,P46776,P62081,P62851,P62753,P62266,Q02543,P26373,P63173,P61247,P61353,P36578,P62861,P62910,P62847,P83881,P18124,P62899,P15880,P84098,P39023,P32969,P60866,P62917,P47914,P62263,P25398,P46781,P46778,P61254,P61313,P46779,P62244 56 +Respiratory electron transport 0.5128352010249048 2.789940293508181 0.0052717762356806 0.9994109559316394 0.712720308882218 59 O75438,O43676,P38117,Q9NPL8,Q9UDW1,P19404,P09669,Q8IUX1,P28331,P14927,Q9BQ95,O14548,P20674,Q9BSH4,Q86Y39,O75380,P08574,P03915,O95139,O43819,O95168,Q9P0J0,Q16795,O14949 24 +Mitochondrial translation 0.5068974313549488 2.774325705973088 0.0055316266043587 0.9995921473774272 0.712720308882218 57 Q7Z7F7,Q5T653,P49406,P82664,Q96RP9,P82914,Q96EY7,Q92665,O75616,Q9Y3D3,P82675,Q8N983,Q9Y2R9,P82912,Q9H2W6 15 +Cellular response to starvation 0.5456374597951796 2.5040334929928987 0.0122786410100395 0.9999999717730144 0.712720308882218 89 P83731,P21283,Q02878,Q9UI12,P61513,P18077,Q9Y3U8,P62424,P50914,P62269,P62701,P62280,P62750,P62841,P62857,P20042,P39019,P36543,Q15382,P08708,P05388,P30050,P62277,P61927,P46777,P40429,P62241,P62854,P46776,P62081,P62851,P62753,P62266,Q02543,P26373,P63173,P61247,P61353,P36578,P62861,P62910,P62847,P83881,P18124,P62899,P15880,P84098,P39023,Q9Y2Q5,P32969,P60866,P62917,P47914,Q6IAA8,Q8N122,P62263,Q9Y5K8,P25398,P46781,P46778,P61254,P61313,P46779,P62244 64 +Srp dependent cotranslational protein targeting to membrane 0.5431370031790955 2.4606319343761696 0.0138692567909022 0.9999999970769298 0.712720308882218 90 P83731,P04844,Q02878,P62424,P61513,P18077,Q9Y3U8,P62269,P50914,P62750,P62701,P62280,P62841,P62857,P39019,Q9Y5M8,P08708,P08240,P05388,O76094,P30050,P62277,P61927,P46777,P40429,P62241,P62854,P46776,P62081,P62851,P62753,P62266,Q02543,P26373,P63173,P61247,P61353,P36578,P62861,P62910,P62847,P83881,P18124,P62899,P15880,P09132,P60468,P84098,P39023,P32969,P60866,P62917,P47914,P62263,P25398,P46781,P46778,P39656,P61254,P51571,P61011,P61313,P62244 63 +Formation of senescence associated heterochromatin foci sahf 0.8437175723785157 2.367768521278282 0.0178957285660004 0.9999999999907584 0.712720308882218 7 P10412,P07305,P17096,P16403 4 +Selenoamino acid metabolism 0.532172835637918 2.353023292695801 0.0186214675798859 0.9999999999967338 0.712720308882218 90 P83731,Q02878,P62424,P61513,P18077,Q9Y3U8,P62269,P50914,P62750,P62701,P62280,P62841,P62857,P39019,Q15046,P08708,P05388,P30050,P62277,P61927,P41252,P46777,P40429,P62241,P62854,P46776,P62081,P62851,P62753,P62266,Q02543,P26373,P63173,P61247,P61353,P36578,P62861,P62910,P62847,P83881,O43324,P62899,P18124,P15880,P84098,P39023,P32969,P60866,P62917,P47914,P62263,P25398,P46781,P46778,P61254,P61313,P62244 57 +Defects in biotin btn metabolism 0.8629182133218107 2.3274066781104628 0.0199436306687434 0.99999999999951 0.712720308882218 6 Q96RQ3,P05165 2 +Rna polymerase ii transcription termination 0.483639852187088 2.2863977011931373 0.0222310027017007 0.9999999999999816 0.712720308882218 46 Q13247,O75152,O95391,O43809,Q86V81,Q9Y3Y2,Q9BY77,Q8NI27,P33240,Q86W42 10 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.443575435982923 2.259188129137815 0.0238716849294784 0.9999999999999982 0.712720308882218 51 Q7L2H7,P62269,P62841,P62701,P62280,P62857,P20042,P39019,O75821,P08708,Q15056,P62277,Q13347,P62241,P62854,P62753,P62266,P62851,P62081,P61247,P62861,P62847,P15880,P60866,P62263,O00303,P25398,P62244 28 +Nonsense mediated decay nmd 0.5124898278923139 2.2152644368735244 0.0267419193257389 1.0 0.712720308882218 87 P83731,Q02878,P62424,P61513,P18077,Q9Y3U8,Q9HAU5,P50914,P62269,P62701,P62280,P62750,P62841,P62857,P39019,P08708,P05388,P30050,P62277,P61927,P46777,P40429,P62241,P62854,P46776,P62081,P62851,P62753,P62266,Q02543,P26373,P63173,P61247,P61353,P36578,P62861,P62910,P62847,P83881,P18124,P62899,P15880,Q9Y5S9,P84098,P39023,P32969,P60866,P62917,P47914,P62263,P25398,P46781,P46778,P61254,P61313,P46779,P62244 57 +Dna damage telomere stress induced senescence 0.7044579601282548 2.175051715600014 0.0296262411770453 1.0 0.712720308882218 15 P10412,P16403,Q15554,P17096,O60934,P62805,P07305 7 +Biotin transport and metabolism 0.7982316977624531 2.171904754054073 0.0298628478236033 1.0 0.712720308882218 7 Q96RQ3,P05165 2 +Wnt5a dependent internalization of fzd4 0.7437339686076052 2.053418791014378 0.0400319783915827 1.0 0.712720308882218 8 O14641 1 +Apoptosis induced dna fragmentation 0.6738746673871531 1.998792501281922 0.0456308094805368 1.0 0.7133616548790599 10 P10412,P07305,P16403,P16402 4 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4501426644561705 1.9403023104693575 0.0523429607595131 1.0 0.7685289537628707 69 P56134,O75438,O43676,P48047,P38117,Q9NPL8,Q9UDW1,P19404,P09669,Q8IUX1,P28331,P14927,Q9BQ95,O14548,P20674,Q9BSH4,Q86Y39,O75380,P08574,P03915,O95139,O43819,O95168,Q9P0J0,Q16795,O14949 26 +Amyloid fiber formation 0.7936569049323822 1.9261221106341888 0.054089128403937 1.0 0.7776435823984615 5 Q9UJY5 1 +Signaling by flt3 fusion proteins 0.7802268391655409 1.8696368387863385 0.0615342659572029 1.0 0.7776435823984615 5 Q92614 1 +B wich complex positively regulates rrna expression 0.6353345325933557 1.8478754618805897 0.0646203610560776 1.0 0.7776435823984615 19 O00159,P62875,O15446,Q9GZS1,O15160,Q9NR30,O60264,Q9NY93,O95602,Q9H9Y6,P62805,Q9BQG0 12 +Positive epigenetic regulation of rrna expression 0.5907971832002381 1.843704338456261 0.0652262404214754 1.0 0.7776435823984615 29 Q92769,Q9NY93,P62805,O00159,O15446,Q9GZS1,O15160,Q13185,P62875,Q9NR30,Q13330,Q14839,O94776,P16104,Q9H9Y6,P19388,O60264,O95602,Q9BQG0 19 +Dna damage reversal 0.7664798307406624 1.811526852660631 0.070059336265384 1.0 0.788910327819873 5 Q8N9N2,Q6P6C2 2 +Activated tak1 mediates p38 mapk activation 0.7642972099817018 1.8022743712681208 0.0715022486921546 1.0 0.7905147821068037 5 P46734 1 +Mrna splicing minor pathway 0.536791532724041 1.763271434949579 0.0778547206468123 1.0 0.7905147821068037 35 P24928,P55769,O75643,Q13247,O94906,Q9BWJ5,P62875,P13984,P62318,P62314,Q13435,Q6P2Q9,Q96DI7,P62304,Q15427,P19388,Q86XP3,Q8TBF4,Q9BUQ8,P62487 20 +Defects in vitamin and cofactor metabolism 0.6539264633045405 1.755815068943274 0.0791199905227577 1.0 0.7905147821068037 9 Q96RQ3,P05165 2 +Signaling by fgfr2 iiia tm 0.6256506906336364 1.7508044947037926 0.0799795921241055 1.0 0.7905147821068037 10 P62875,P19388,P24928,P13984,P62487 5 +Fgfr2 mutant receptor activation 0.6256506906336364 1.7508044947037926 0.0799795921241055 1.0 0.7905147821068037 10 P62875,P19388,P24928,P13984,P62487 5 +Complex i biogenesis 0.5497513015647201 1.7474045145487709 0.0805671949356303 1.0 0.7905147821068037 33 O95139,O75438,O43676,Q86Y39,Q8IUX1,O95168,O75380,P28331,Q9NPL8,P03915,Q9P0J0 11 +Deposition of new cenpa containing nucleosomes at the centromere 0.6462235649546901 1.7177123553779043 0.0858490946120658 1.0 0.7905147821068037 9 Q92674,O60264,Q96T23,P16104,Q16576,P62805,Q71F23,P06748 8 +G protein beta gamma signalling 0.6914705707055617 1.6965340183172608 0.089784793427134 1.0 0.7922718311934912 7 P31749,P60953,Q01970 3 +Cd163 mediating an anti inflammatory response 0.8646641492844572 1.693118142879658 0.0904329815231035 1.0 0.7922718311934912 3 Q16539 1 +Synaptic adhesion like molecules 0.7114965350237267 1.6845825226960631 0.0920691456643694 1.0 0.7922718311934912 6 P41440 1 +Dcc mediated attractive signaling 0.789342232846882 1.6770747495078706 0.0935278657403357 1.0 0.7967191846755033 4 O75962 1 +Rab geranylgeranylation 0.5909682586062 1.663501193504501 0.0962121521460632 1.0 0.799721248043796 23 Q92930,Q9NP72,P51148,Q15286,P20339,P61019,P51153,Q9BZG1,P62820,P20338 10 +Eukaryotic translation initiation 0.4819403571284137 1.6559049750506645 0.0977410639659441 1.0 0.799721248043796 101 P83731,Q7L2H7,Q02878,P62424,P61513,P18077,Q9Y3U8,P62269,P50914,P62750,P62701,Q9UI10,P62280,Q9NR50,P62857,P62841,P20042,P39019,O75821,P08708,P05388,P30050,Q15056,P62277,P61927,Q13347,P46777,P40429,P62241,P62854,P46776,P62081,P62851,P62753,P62266,Q02543,P26373,P63173,P61247,P61353,P36578,P62861,P62910,P62847,P83881,P18124,P62899,P15880,O60841,P84098,P39023,P32969,P60866,P62917,P47914,P62263,O00303,P25398,P46781,P46778,P61254,P61313,P62244 63 +Chromosome maintenance 0.3851557826899682 1.6386376289450506 0.1012887507207787 1.0 0.799721248043796 51 P24928,Q15554,Q96T23,Q5H9R7,P62805,Q71F23,P41440,P06748,P19387,P49642,P39748,O60832,Q9BUR4,P62875,Q9Y2S7,P16104,P35251,P46100,P54132,P0CG13,P19388,O60264,P40937,P28340,P49005,P62487 26 +Rab regulation of trafficking 0.475464794956708 1.621497548176052 0.1049109753857457 1.0 0.799721248043796 40 Q92930,Q9NP72,Q9HA65,Q15286,P51148,P62330,P31749,Q9UJY5,P20339,P51153,Q5VZ89,P62820 12 +Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.5982485649278086 1.6079866589125626 0.1078381006852209 1.0 0.799721248043796 10 O95782,P53680,Q10567,P04439,O94973 5 +Regulation of pyruvate dehydrogenase pdh complex 0.6706368141073146 1.6015494246192947 0.1092552823036303 1.0 0.799721248043796 7 P10515,P09622,Q15120,P08559,Q8NCN5 5 +Myogenesis 0.6907395134850096 1.5935171030401778 0.1110442346276903 1.0 0.799721248043796 6 P60953 1 +Metabolism of folate and pterines 0.6167296143370193 1.5709882421399384 0.1161853799315282 1.0 0.8052848746978335 9 P41440 1 +Protein protein interactions at synapses 0.581159704432084 1.5093209597752877 0.1312167809359179 1.0 0.8336352076157159 14 P10586,P41440 2 +Rna polymerase iii transcription initiation from type 1 promoter 0.5738404974926573 1.4799448847884176 0.1388879558965872 1.0 0.8336352076157159 10 P62875,O15160,Q12789,Q9Y5Q8,Q9Y5Q9,Q8WUA4 6 +Rna polymerase i promoter escape 0.5745574365797672 1.4734882951149997 0.1406194176895141 1.0 0.8336352076157159 14 P62875,O15446,Q9GZS1,O15160,P19388,Q13185,O95602,Q9H9Y6,P17480,P62805 10 +Integrin cell surface interactions 0.7390648567119165 1.4723766679912056 0.1409191901609072 1.0 0.8336352076157159 4 Q9Y624,P35613,Q08722 3 +Trafficking of glur2 containing ampa receptors 0.6603194660701295 1.4591272483128432 0.1445300878167987 1.0 0.8336352076157159 6 O95782,P53680 2 +Rna polymerase iii transcription 0.5699718699570693 1.4542070424246762 0.145888913107413 1.0 0.8336352076157159 11 P62875,O15160,Q12789,Q9Y5Q8,Q9Y5Q9,Q8WUA4 6 +Rna polymerase i transcription termination 0.569044397288262 1.4492918421153314 0.1472560983353874 1.0 0.8336352076157159 11 P62875,O15446,Q9GZS1,O15160,O95602,Q9H9Y6,P17480 7 +Loss of function of mecp2 in rett syndrome 0.6541333237084084 1.4316881129007453 0.1522330998631282 1.0 0.8336352076157159 6 Q9BZK7,Q96ST3 2 +Cytosolic sulfonation of small molecules 0.6768780021632961 1.426708789725192 0.153663851020307 1.0 0.8336352076157159 5 Q96IU4,Q8TB61 2 +Regulation of pten gene transcription 0.5619963208120597 1.422219373447533 0.1549625763139097 1.0 0.8336352076157159 18 Q15022,Q9Y2Q5,Q92769,Q13330,Q6IAA8,Q14839,Q8N122,O94776,Q15382 9 +Regulation of tp53 activity through acetylation 0.5644827745166255 1.4212290615235434 0.1552501786596394 1.0 0.8336352076157159 12 Q92769,Q14839,P31749,P78356,O94776,Q9HAF1 6 +Cardiac conduction 0.5632603385416102 1.4146973650037318 0.157157247300764 1.0 0.8336352076157159 12 Q12797,P20020,P17612,Q9HD47,Q99996,P54709,Q13555,P16615 8 +Transcriptional regulation of white adipocyte differentiation 0.5633038855055211 1.413807834242396 0.1574183327020497 1.0 0.8336352076157159 15 Q9BZK7,O60244,Q13503 3 +Fgfr2 alternative splicing 0.5603751994744531 1.4060051005723182 0.1597226101890836 1.0 0.8336352076157159 17 P62875,P19388,P24928,P13984,P52272,P62487,Q01085,P31483 8 +The role of nef in hiv 1 replication and disease pathogenesis 0.5610566184128369 1.4029215372950734 0.1606402376947207 1.0 0.8336352076157159 12 O95782,P53680,Q10567,P04439,O94973 5 +Nef mediated cd8 down regulation 0.6472556775873294 1.4011472292575131 0.1611700508228801 1.0 0.8336352076157159 6 O95782,O94973,P53680 3 +Nef mediated cd4 down regulation 0.6472556775873294 1.4011472292575131 0.1611700508228801 1.0 0.8336352076157159 6 O95782,O94973,P53680 3 +Epigenetic regulation of gene expression 0.4392389120072141 1.3964593504538605 0.1625762133765174 1.0 0.8336352076157159 41 Q92769,Q9NY93,Q96ST3,P62805,Q15022,O00159,O15446,Q9GZS1,O15160,Q13185,P62875,Q9NR30,Q13330,Q14839,O94776,P16104,Q9H9Y6,P17480,P19388,O60264,O95602,Q9BQG0 22 +Met activates ptk2 signaling 0.7183931792563513 1.3876742055558866 0.1652362740213433 1.0 0.8336352076157159 4 P11047 1 +Propionyl coa catabolism 0.7844002056724111 1.3828859268362133 0.1666998461229905 1.0 0.8336352076157159 3 P05165 1 +Signaling by notch1 pest domain mutants in cancer 0.5791194528697933 1.3825034160934635 0.1668171822990196 1.0 0.8336352076157159 9 Q9BZK7 1 +Formation of the beta catenin tcf transactivating complex 0.5789057075625081 1.3814296847383445 0.1671468839068488 1.0 0.8336352076157159 9 Q15291,P51532,P16104,P35222,P62805 5 +Recognition and association of dna glycosylase with site containing an affected purine 0.6642946913095705 1.3720592537448766 0.1700449925982305 1.0 0.8336352076157159 5 Q15554 1 +Base excision repair ap site formation 0.6642946913095705 1.3720592537448766 0.1700449925982305 1.0 0.8336352076157159 5 Q15554 1 +Triglyceride metabolism 0.6181458148685278 1.3600974515425142 0.1737990874379338 1.0 0.8397242957263279 7 P62140,O60664,P43304,P62136,Q9HCL2 5 +Retrograde transport at the trans golgi network 0.5453426383883346 1.359043897797097 0.1741326787825938 1.0 0.8397242957263279 21 Q96JB2,P53365,Q7Z6M1 3 +G beta gamma signalling through pi3kgamma 0.7763677223577641 1.3516789713628252 0.1764780349900228 1.0 0.8397242957263279 3 P31749 1 +Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.5499856953944675 1.3437564928164345 0.1790271426080925 1.0 0.8463266939298264 12 Q92769,Q13330,Q13185,Q14839,O94776,P16104,P62805 7 +Rna polymerase i transcription 0.5339348198513737 1.3407959008165655 0.1799867274870159 1.0 0.8463266939298264 24 P62875,Q92769,O15446,O15160,Q9GZS1,Q13330,Q13185,Q14839,P19388,O95602,O94776,P16104,Q9H9Y6,P17480,P62805 15 +Wnt mediated activation of dvl 0.7720144752714422 1.3347630586165216 0.1819539076335874 1.0 0.8463266939298264 3 P19784,O14641 2 +Meiotic recombination 0.5471212560524089 1.3330337228598403 0.1825207373552748 1.0 0.8463266939298264 11 P62805,P54132 2 +Flt3 signaling in disease 0.6072970134517817 1.3099643048469696 0.1902079113118375 1.0 0.8463266939298264 7 Q92614 1 +Mecp2 regulates transcription of neuronal ligands 0.7634733082303599 1.3015723948766704 0.1930626016304586 1.0 0.8463266939298264 3 Q96ST3 1 +The citric acid tca cycle and respiratory electron transport 0.4456166888093431 1.3011465277283327 0.193208304275652 1.0 0.8463266939298264 101 P56134,O75438,P50213,O43676,P48047,P38117,Q16775,Q6P587,Q9NPL8,Q96I99,Q99798,Q9UDW1,P10515,P19404,P09669,Q02218,Q8IUX1,O95563,P08559,P28331,P14927,Q9BQ95,O14548,P20674,P09622,Q9BSH4,Q86Y39,Q04760,Q15120,O75380,P08574,P03915,P23368,P36957,O95139,O43819,P35613,O95168,Q9P0J0,Q9P2R7,Q16795,O14949 42 +Rrna processing 0.5426041334145589 1.2980705630818563 0.1942630885761951 1.0 0.8463266939298264 163 P22087,P61513,P55769,Q2NL82,Q68CQ4,Q92979,P62857,Q8TED0,Q01780,P05388,Q8TCT8,P61927,P46087,P62241,P46776,P62081,P62851,Q96B26,P56182,Q13868,Q9NR30,Q99848,O15213,P62847,Q99547,P47914,Q9NW13,Q9NXG2,P62244,Q14137,O00541,P18077,Q9Y3U8,P50914,P62701,P62280,P39019,Q9Y4W2,O43709,P61247,P61353,Q9Y2L1,P84098,Q9Y3A2,P61313,Q8IY81,Q02878,Q9BVJ6,P62424,Q9NY93,O00567,P08708,P30050,Q13601,P62854,P62753,P62266,Q9Y6V7,P36578,P62861,P62910,P83881,P62899,Q14690,Q5RKV6,P78346,Q8NI36,Q9H9L3,Q9H583,P83731,P62269,P62750,P62841,O15091,Q9H0A0,P62277,P46777,P40429,Q02543,Q15061,O60832,P26373,P63173,Q12788,Q9H0S4,Q9UNQ2,P18124,Q9Y2P8,P15880,P39023,P32969,P60866,P62917,P62263,P46778,Q13895,Q06265 97 +Hdr through mmej alt nhej 0.6032405706014902 1.2912124320402696 0.1966300253778889 1.0 0.8486455389775761 7 P09874,O60934,P39748,P18887 4 +Hdacs deacetylate histones 0.5370592353861552 1.271422959446281 0.203578218960621 1.0 0.8551037168340554 13 Q92769,Q13330,Q14839,Q9BZK7,O94776,P62805 6 +Transport of mature transcript to cytoplasm 0.3754838806575915 1.2685707036920504 0.2045942186596645 1.0 0.8551037168340554 64 Q13247,O75152,O95391,Q86V81,Q92620,Q8NFH5,Q9Y3Y2,Q9BY77,Q8NI27,Q9BTX1,Q86W42 11 +Ksrp khsrp binds and destabilizes mrna 0.5362778982393013 1.2657592954957004 0.2055992721597865 1.0 0.8551037168340554 15 Q13868,Q5RKV6,Q16539,P31749,Q06265 5 +Netrin 1 signaling 0.5353610752577178 1.265649160429362 0.205638717366603 1.0 0.8551037168340554 12 O75962,P60953 2 +Attachment of gpi anchor to upar 0.7530278106062831 1.26099031279538 0.2073123373523566 1.0 0.8551037168340554 3 Q96S52 1 +Oxidative stress induced senescence 0.5341893085560014 1.255989755297836 0.2091196844504528 1.0 0.8551037168340554 13 P42771,P62805,Q16539,P46734 4 +Inactivation of cdc42 and rac1 0.7513473343309391 1.254463404296972 0.2096736192663462 1.0 0.8551037168340554 3 P60953 1 +Trafficking of ampa receptors 0.5523149544633673 1.247838573274976 0.2120901795249641 1.0 0.8582186432466827 9 O95782,Q13555,O94973,P53680 4 +Tbc rabgaps 0.5261598245765088 1.247330355835042 0.2122763912890359 1.0 0.8582186432466827 21 Q92930,Q15286,Q9HA65,P51148,P62330,P20339,Q9UJY5,P20338 8 +Signaling by notch1 0.5272853068872216 1.2349114791708218 0.2168634507600826 1.0 0.8624026607379242 10 Q9BZK7 1 +Pyruvate metabolism 0.5302344228196146 1.2327277708680668 0.217677347159555 1.0 0.8624026607379242 15 P10515,Q15120,Q04760,P35613,O95563,Q16775,P08559 7 +Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.680547045813231 1.2322811098965356 0.2178440936950239 1.0 0.8624026607379242 4 Q96ST3,P04179 2 +Mitochondrial trna aminoacylation 0.5287707929560352 1.2296756583713084 0.2188185855603688 1.0 0.8624026607379242 17 Q5T160,Q9BW92,Q15031,Q5ST30,Q5JTZ9,Q9H2U2,Q9NP81,Q9UGM6 8 +Cd28 co stimulation 0.5666961313485549 1.2142100969566676 0.2246675058101095 1.0 0.8708186795449699 8 P31749 1 +Prc2 methylates histones and dna 0.6236679375455215 1.1953319530044897 0.2319573603185223 1.0 0.8877947492534665 5 Q15022,P62805,P16104 3 +Triglyceride catabolism 0.5965522597644174 1.1754309129932874 0.2398223620285602 1.0 0.8974203813143198 6 P62140,O60664,P62136,P43304 4 +Ketone body metabolism 0.5957579163883567 1.1718953302362691 0.241239082143402 1.0 0.8989627715501445 6 P55809,Q9BUT1 2 +Role of abl in robo slit signaling 0.6143453202161155 1.15481699501631 0.2481653760164683 1.0 0.906931646896548 5 O75122,P40123 2 +Loss of mecp2 binding ability to the ncor smrt complex 0.7224652646107805 1.142471828079184 0.2532579496524776 1.0 0.9147954604774696 3 Q9BZK7 1 +Ion homeostasis 0.5068591154968605 1.1278053572834823 0.2594021303843279 1.0 0.9237924441389448 10 Q12797,P20020,P17612,P54709,Q13555,P16615 6 +Nef mediated downregulation of mhc class i complex cell surface expression 0.6547190748573286 1.1263880920615386 0.2600012849175708 1.0 0.9237924441389448 4 Q10567 1 +Gpvi mediated activation cascade 0.6069014432693322 1.1225062048485173 0.2616472708389925 1.0 0.9272990178097292 5 P61586,P60953 2 +Cell cell junction organization 0.5450413302554344 1.1103174878067736 0.2668622399133227 1.0 0.9397930039819138 8 Q9BY67,Q9Y624,P35222,P14923 4 +Free fatty acids regulate insulin secretion 0.650611761806769 1.109588463404534 0.2671764048278362 1.0 0.9397930039819138 4 P29992,Q01970 2 +Rna polymerase i transcription initiation 0.5032285818927515 1.105241750499089 0.2690548504188248 1.0 0.942662839251307 20 P62875,Q92769,O15446,O15160,Q9GZS1,Q13330,P19388,Q14839,O95602,O94776,Q9H9Y6,P17480 12 +Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.5618972984570849 1.1003481758060625 0.2711804492278165 1.0 0.942662839251307 7 O95782,P53680 2 +Vldlr internalisation and degradation 0.5618972984570849 1.1003481758060625 0.2711804492278165 1.0 0.942662839251307 7 O95782,P53680 2 +Amino acids regulate mtorc1 0.5028143143886878 1.0926889236623256 0.274530404602084 1.0 0.942662839251307 12 P21283,Q6IAA8,Q8N122,Q9Y5K8,Q15382 5 +Enos activation 0.643002949940104 1.0785096125012297 0.2808063943362238 1.0 0.9508072060414944 4 P31749,O75608 2 +Diseases associated with n glycosylation of proteins 0.5961555765174162 1.0759500203235273 0.2819496094780609 1.0 0.9508072060414944 5 O75340,Q13724 2 +Signaling by cytosolic fgfr1 fusion mutants 0.5363959712578352 1.0690020014420154 0.2850687675555408 1.0 0.9508072060414944 8 Q92614 1 +Mrna decay by 3 to 5 exoribonuclease 0.5000399658380158 1.068702142652832 0.2852039057520992 1.0 0.9508072060414944 15 Q96B26,Q5RKV6,Q06265,Q13868 4 +Fgfr1 mutant receptor activation 0.4950810297422239 1.0663920459329828 0.2862464557913955 1.0 0.9508072060414944 10 Q92614 1 +Wax and plasmalogen biosynthesis 0.6400049983755518 1.066281434212465 0.2862964395278407 1.0 0.9508072060414944 4 O00116,Q8WVX9 2 +Rab gefs exchange gtp for gdp on rabs 0.4778143856745703 1.0596119450682882 0.2893211770628641 1.0 0.9555748735386144 27 Q92930,Q9NP72,P51148,P31749,P20339,P51153,Q5VZ89,P62820 8 +Slbp dependent processing of replication dependent histone pre mrnas 0.6975689348848407 1.0464523222794095 0.2953522465597862 1.0 0.9641777515304388 3 P62318 1 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.4935938089203471 1.0391469532019368 0.2987363968995919 1.0 0.9670668304329784 13 Q13868,Q5RKV6,P31749,Q96B26,Q06265 5 +Telomere maintenance 0.3625047189110741 1.0386091540396185 0.2989865467223493 1.0 0.9670668304329784 45 P24928,Q15554,Q5H9R7,P41440,P62805,P19387,P49642,P39748,O60832,Q9BUR4,P62875,Q9Y2S7,P16104,P35251,P46100,P54132,P0CG13,P19388,P28340,P49005,P62487 21 +Basigin interactions 0.5605550569991807 1.0157207802523684 0.3097623695863825 1.0 0.9735248271870116 6 P08195,P35613 2 +Trna aminoacylation 0.4273081477454754 1.0147294743380568 0.3102348001582564 1.0 0.9735248271870116 36 Q5T160,Q9BW92,Q15031,Q5ST30,Q5JTZ9,Q9Y285,O43324,Q9H2U2,Q9NP81,Q9UGM6 10 +Rho gtpases activate iqgaps 0.4858748963248314 1.0103803072336186 0.3123131190054526 1.0 0.9735248271870116 11 Q13576 1 +Degradation of the extracellular matrix 0.4870857239836227 1.0099664839135805 0.3125113479448813 1.0 0.9735248271870116 12 P11047,P17655,P42574,P35613,P78536 5 +Receptor mediated mitophagy 0.6869722557298051 1.0058162512942097 0.3145039683117185 1.0 0.9735248271870116 3 P19784,P67870 2 +Signaling by fgfr1 in disease 0.4849136412826181 1.005384394286997 0.3147117913987096 1.0 0.9735248271870116 11 Q92614 1 +Apobec3g mediated resistance to hiv 1 infection 0.6830758240042423 0.9909183661700376 0.3217254434185435 1.0 0.9808632300838868 3 P17096 1 +Serine biosynthesis 0.6823943418246685 0.988315387552996 0.3229982116921581 1.0 0.9808632300838868 3 P78330 1 +Mecp2 regulates neuronal receptors and channels 0.5346372992596555 0.9754937469075684 0.3293154019564259 1.0 0.9858441926653004 7 Q9NWH9,Q96ST3 2 +Retrograde neurotrophin signalling 0.5151424986159971 0.9680698046394792 0.3330095088882001 1.0 0.9869044813022132 8 O95782,P53680 2 +Sumoylation of transcription factors 0.5673161500022537 0.9518026753514072 0.341197064987158 1.0 0.9960557619121968 5 P42771,Q13330 2 +Transport of vitamins nucleosides and related molecules 0.5459564042524716 0.9514581765117422 0.3413718399352476 1.0 0.9960557619121968 6 Q8TB61 1 +Piwi interacting rna pirna biogenesis 0.4926186484703685 0.9506887092995432 0.341762421430152 1.0 0.9960557619121968 9 P19388,P24928,P62875,P62487 4 +Tp53 regulates metabolic genes 0.3824722502234758 0.9325887100411429 0.3510323647757682 1.0 1.0 41 O14548,P20674,P09669,Q9BSH4,O43819,Q6IAA8,P31749,Q15382 8 +Regulation of lipid metabolism by pparalpha 0.468870721097206 0.9198015229986354 0.3576764873412301 1.0 1.0 21 Q9BZK7,O60244,Q13503 3 +Hiv transcription initiation 0.4705257762312036 0.9181667496704566 0.3585315734237229 1.0 1.0 13 P62875,Q00403,P19388,P24928,P13984,P62487 6 +Gluconeogenesis 0.4694338131671954 0.9157806830421752 0.359781937111626 1.0 1.0 20 P18669,P00505,Q16822,P04406,P09972,P60174,P00558,Q9UBX3,P11498,P53007,Q02978,P40925,P40926,P06733 14 +Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0.6613389626055476 0.908336423951464 0.3637005040110141 1.0 1.0 3 P46087,P06748 2 +Regulation of mecp2 expression and activity 0.4648610677045616 0.902032349252988 0.367039683661591 1.0 1.0 11 Q9BZK7,Q96ST3,P42858 3 +Transcriptional regulation by mecp2 0.4670802663831494 0.8931797957704142 0.3717608960505956 1.0 1.0 15 Q9NWH9,P42858 2 +L1cam interactions 0.360606272282886 0.8790387927234751 0.379380242602287 1.0 1.0 43 Q13740,O15020 2 +Foxo mediated transcription 0.4546111618683048 0.8499775511064741 0.3953375672706831 1.0 1.0 11 P31749,P04179 2 +Cell surface interactions at the vascular wall 0.4569950256574094 0.8484483728785316 0.3961883127987886 1.0 1.0 13 P08195,Q9Y624,P14174,P35613 4 +Polymerase switching 0.456752020211915 0.8425650690225294 0.3994717339507636 1.0 1.0 14 P49642,Q9Y2S7,P28340,P49005,P41440,P35251 6 +Thrombin signalling through proteinase activated receptors pars 0.5415239927292046 0.8423427370083646 0.3995961356925048 1.0 1.0 5 Q14344 1 +Polymerase switching on the c strand of the telomere 0.4567398626780662 0.8388002725276182 0.401581397766318 1.0 1.0 18 P0CG13,P41440,Q9Y2S7,Q15554 4 +Adherens junctions interactions 0.4991767129769386 0.8158981078666824 0.414558414429218 1.0 1.0 7 Q9BY67,P35222,P14923,P55196 4 +Pyruvate metabolism and citric acid tca cycle 0.4068461337245344 0.7990679330716794 0.4242510223054374 1.0 1.0 34 P50213,Q16775,Q6P587,Q96I99,Q99798,P31040,P10515,Q02218,O95563,P08559,P09622,Q15120,Q04760,P11177,P23368,O75390,P36957,P35613,Q8NCN5,Q9P2R7 20 +Telomere extension by telomerase 0.4435339570612028 0.7944591643113206 0.4269281728227196 1.0 1.0 11 Q5H9R7,Q15554 2 +Atf4 activates genes in response to endoplasmic reticulum stress 0.4415415918349095 0.7703161410053748 0.4411123839837714 1.0 1.0 13 Q96B26,Q5RKV6,Q06265,Q13868 4 +Synthesis of ketone bodies 0.5235377118830283 0.7673185307633386 0.4428921534303365 1.0 1.0 5 Q9BUT1,P35914 2 +Glyoxylate metabolism and glycine degradation 0.436913798787406 0.7538170438982523 0.4509590882300038 1.0 1.0 12 P36957,P10515,P00505,Q02218,P08559,P30038 6 +Activation of anterior hox genes in hindbrain development during early embryogenesis 0.4385403850591185 0.7436614691317616 0.457081305407512 1.0 1.0 18 Q15022,P19387,P62875,P19388,P24928,Q15291,P62487,P16104,Q16576,P62805 10 +Energy dependent regulation of mtor by lkb1 ampk 0.4310085782054139 0.7420693609142305 0.4580453122836752 1.0 1.0 10 Q6IAA8,Q8N122,Q15382 3 +Influenza infection 0.4242475905360331 0.7374080094896328 0.4608742661580256 1.0 1.0 127 P83731,Q02878,P09874,P61513,P18077,Q9Y3U8,P24928,P37198,P50914,P62701,P62280,P62424,Q9UKX7,P62857,P49790,P62841,P39019,Q86U42,P08708,P19387,P30050,P62277,Q12849,P46777,P40429,P62854,P46776,P62081,P62753,P62266,Q02543,Q5SRE5,Q9BTX1,P62269,P26373,P62875,P62750,P63173,P61247,P13984,P61353,P36578,P62861,P62910,P62847,P83881,P18124,P62899,P15880,P84098,P39023,P32969,P60866,P62917,P78406,P47914,P19388,P62263,Q8NFH5,P46778,P62487,P61313,P62244,Q8TEM1 64 +Processive synthesis on the c strand of the telomere 0.4346995141331625 0.736328783229224 0.4615306335928593 1.0 1.0 13 P54132,Q15554 2 +Eph ephrin mediated repulsion of cells 0.4471491637400975 0.7326571708765124 0.4637675522531173 1.0 1.0 9 O95782,P53680 2 +Intra golgi traffic 0.4345052395190044 0.726262359399359 0.4676779497502956 1.0 1.0 15 Q16706,Q96JB2 2 +Post translational modification synthesis of gpi anchored proteins 0.4757918848285636 0.7135043971816696 0.4755336931318341 1.0 1.0 7 Q969N2,Q96S52 2 +Tnf signaling 0.4246626576671746 0.7113779719208895 0.476850045589954 1.0 1.0 10 Q8TCT8 1 +Acetylcholine regulates insulin secretion 0.6071946076243223 0.7082991585318468 0.4787594995502355 1.0 1.0 3 Q01970 1 +Signaling by fgfr2 in disease 0.4268923992466761 0.7047781646280937 0.480948299131817 1.0 1.0 12 P62875,P19388,P24928,P13984,P62487 5 +Processing and activation of sumo 0.6001206272617602 0.6829849371740154 0.4946163606746625 1.0 1.0 3 P61956,Q9UBT2 2 +Sumo is transferred from e1 to e2 ube2i ubc9 0.6001206272617602 0.6829849371740154 0.4946163606746625 1.0 1.0 3 P61956,Q9UBT2 2 +Sumo is conjugated to e1 uba2 sae1 0.6001206272617602 0.6829849371740154 0.4946163606746625 1.0 1.0 3 P61956,Q9UBT2 2 +Mrna capping 0.4221062265058889 0.6749123240351697 0.4997314701456485 1.0 1.0 13 P62875,P19388,P24928,P13984,P62487 5 +Extension of telomeres 0.3869863134408529 0.6734095663557194 0.5006867642523325 1.0 1.0 34 P54132,Q9Y2S7,P0CG13,Q15554,Q5H9R7,P41440,O60832 7 +Circadian clock 0.420657782292265 0.6679519127118092 0.5041642884362296 1.0 1.0 13 Q9BZK7 1 +Crmps in sema3a signaling 0.4984391259742802 0.6651014746389444 0.5059855915378073 1.0 1.0 5 Q9BPU6 1 +Negative epigenetic regulation of rrna expression 0.4170557445130077 0.6550442813054446 0.5124392443633958 1.0 1.0 23 P62875,Q92769,O15446,Q9GZS1,O15160,P19388,O60264,O95602,Q96ST3,Q9H9Y6,P17480,P62805 12 +Met promotes cell motility 0.4300687836316481 0.6542764869794253 0.5129336915860483 1.0 1.0 9 P11047 1 +Rna polymerase iii transcription termination 0.4754835110706336 0.6508184697627991 0.5151636760565292 1.0 1.0 6 O15160 1 +Inhibition of dna recombination at telomere 0.4156858115842111 0.6442350721025683 0.5194230113466887 1.0 1.0 13 P19387,P46100,P62875,P19388,P24928,Q15554,P62487,P62805 8 +Meiosis 0.4067222127923027 0.6302358904842794 0.5285402605874219 1.0 1.0 26 P62805,P54132,O94901,Q15554 4 +Rho gtpases activate paks 0.4112853193953014 0.6234812119606632 0.5329683448807325 1.0 1.0 13 P60953 1 +Reduction of cytosolic ca levels 0.5829312424608007 0.6224985479720551 0.5336140982611333 1.0 1.0 3 P20020,P16615 2 +Platelet calcium homeostasis 0.5829312424608007 0.6224985479720551 0.5336140982611333 1.0 1.0 3 P20020,P16615 2 +Branched chain amino acid catabolism 0.4101883680580617 0.618343791400035 0.5363487410798451 1.0 1.0 13 Q96RQ3,O15382 2 +Trna modification in the nucleus and cytosol 0.4111701617385505 0.6096809795839941 0.5420731566164052 1.0 1.0 16 Q9NXH9,Q8TEA1,Q5VV42,Q9H974,Q9NPF4 5 +Maturation of sars cov 2 spike protein 0.4068102588027138 0.6095552733200997 0.5421564475300511 1.0 1.0 12 Q16706,P04844,P39656,Q13724,P46977 5 +Rna polymerase iii chain elongation 0.4806252884908562 0.5947928626091704 0.5519819390966827 1.0 1.0 5 O15160 1 +Rna polymerase iii transcription initiation from type 3 promoter 0.4806252884908562 0.5947928626091704 0.5519819390966827 1.0 1.0 5 O15160 1 +Neurexins and neuroligins 0.4322569911055335 0.5930404087536639 0.553154109514612 1.0 1.0 8 Q9HCM4 1 +Defective intrinsic pathway for apoptosis 0.4056607091834284 0.5837400789354221 0.559395198071589 1.0 1.0 16 Q07021,P42771,P17655,P04179 4 +Dual incision in tc ner 0.3587410274600846 0.5594864035295892 0.575829807892505 1.0 1.0 36 P62875,Q9Y2S7,Q9UNP9,P24928,P19388,P05114,P28340,Q9UMS4,P49005,P62487,Q9ULR0,P41440,O60306,P35251 14 +Microrna mirna biogenesis 0.3932070890488266 0.5559503581097265 0.5782447912166093 1.0 1.0 11 P19388,P24928,P62875,P62487 4 +Perk regulates gene expression 0.3971941896661815 0.5481994960090018 0.5835549281383687 1.0 1.0 15 Q96B26,Q5RKV6,Q06265,Q13868 4 +Stat3 nuclear events downstream of alk signaling 0.5051729416725927 0.5425603255330949 0.5874325617314153 1.0 1.0 4 Q96ST3 1 +Acyl chain remodeling of cl 0.801025022610794 0.5421367631073268 0.5877242946081735 1.0 1.0 2 P55084 1 +Cellular senescence 0.3457478870471347 0.5418553213340982 0.5879181775087723 1.0 1.0 38 P10412,P16403,P16402,Q16539,Q15554,P17096,O60934,P07305,P62805,P46734 10 +Telomere c strand lagging strand synthesis 0.3908292921773769 0.5387067585134273 0.5900892095621761 1.0 1.0 25 P54132,Q9Y2S7,P0CG13,Q15554,P41440 5 +Reproduction 0.3863241038824429 0.5364928705111058 0.5916179619481576 1.0 1.0 27 P62805,P54132,O94901,Q15554 4 +Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.5536791314837209 0.5235041557445126 0.600623459825516 1.0 1.0 3 Q9Y6K9,P61088 2 +Sumoylation of dna damage response and repair proteins 0.3196730293676922 0.5229246317307973 0.6010267027162335 1.0 1.0 42 P54132,P78406,P09874,P42771,P37198,Q96SB8,P49790,O60216,Q8NFH5,Q5SRE5,Q14676,Q9BTX1,Q8TEM1 13 +Extracellular matrix organization 0.3664330869455605 0.5094454143932614 0.6104400503945162 1.0 1.0 32 P11047,P17655,P35613,Q9Y624,O60568,P78536 6 +Trna processing 0.2877721174186685 0.5049062917823451 0.6136246547897377 1.0 1.0 61 Q9NXH9,Q9UJA5,P78406,Q99575,P37198,Q969Y2,Q8NFH5,Q8TEA1,Q5VV42,Q5SRE5,Q9H974,P33240,Q9BTX1,Q9NPF4 14 +Interleukin 4 and interleukin 13 signaling 0.3820685485625701 0.492220649583049 0.622563368156416 1.0 1.0 13 P31749 1 +Rrna processing in the mitochondrion 0.4533282501908065 0.4917036180303677 0.6229288801786947 1.0 1.0 5 O15091 1 +Signal transduction by l1 0.3702551787097949 0.4666504184231094 0.6407500085512159 1.0 1.0 10 P19784,P67870 2 +Citric acid cycle tca cycle 0.3797085065734602 0.4630700228032281 0.6433141764471393 1.0 1.0 19 P36957,P31040,P09622,P50213,Q02218,O75390,Q6P587,Q96I99,Q99798,Q9P2R7,P23368 11 +Glutamate and glutamine metabolism 0.4119483094934346 0.4540345585745963 0.6498039534057463 1.0 1.0 7 P00505,Q96C36,P04181,P54886,P32322 5 +Sumoylation 0.3023919232746012 0.4532444129546762 0.6503727548926885 1.0 1.0 74 Q53HL2,Q92769,P09874,P37198,Q9UKX7,Q96ST3,P49790,P62805,Q15022,P11388,P42771,Q5SRE5,Q15424,Q96SB8,Q9BTX1,Q14676,Q13330,O60216,Q9NQS7,P54132,P78406,P11387,Q02880,Q8NFH5,Q8TEM1 25 +N glycan trimming in the er and calnexin calreticulin cycle 0.3718621802949098 0.4436279675219021 0.6573115820272311 1.0 1.0 14 Q9BUN8,Q14165,Q13724 3 +Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.3697835503897873 0.4409926899808647 0.659218289095703 1.0 1.0 13 Q96B26,Q5RKV6,Q06265,Q13868 4 +Collagen biosynthesis and modifying enzymes 0.3657707278608034 0.4394751434730549 0.6603172889143556 1.0 1.0 11 O60568 1 +Signaling by fgfr in disease 0.373328035598566 0.4378420630929822 0.6615007767925816 1.0 1.0 21 O15164,P62875,Q92614,P19388,P24928,P13984,Q9UBW7,O94905,P62487 9 +Sphingolipid de novo biosynthesis 0.362799309486859 0.4363989247800101 0.6625473189436557 1.0 1.0 10 Q9NRA0,Q9P0L0,Q06136 3 +Meiotic synapsis 0.3720154543183726 0.4311202654165928 0.6663809260709068 1.0 1.0 18 Q15554,P62805,O94901,O60216 4 +Metabolism of steroid hormones 0.4159470853899245 0.4211938042449762 0.6736135682443891 1.0 1.0 6 Q8NBQ5 1 +Rac1 gtpase cycle 0.276894337650984 0.4160784966679625 0.6773525643890732 1.0 1.0 46 O75962,Q13576,Q07960,Q86Y07 4 +Met receptor recycling 0.4138005036620535 0.4135650278094111 0.6791926897433158 1.0 1.0 6 P62330,Q9NWH9 2 +Golgi cisternae pericentriolar stack reorganization 0.3591216802701283 0.4131400504076458 0.6795040076118473 1.0 1.0 11 P62820 1 +Ngf stimulated transcription 0.5159403311522182 0.405016616319335 0.6854652970033319 1.0 1.0 3 Q14839 1 +Erbb2 regulates cell motility 0.5154833590697763 0.4036566148953711 0.6864652472848751 1.0 1.0 3 P61586 1 +G alpha 12 13 signalling events 0.3685299454494515 0.3984939342657285 0.6902661286345912 1.0 1.0 9 Q9H8V3,P61586,O75962,Q14344 4 +Apoptotic cleavage of cell adhesion proteins 0.4088414193447083 0.3961499023875152 0.6919944464470378 1.0 1.0 6 P42574,P15924,Q14126 3 +Wnt ligand biogenesis and trafficking 0.4256428390875147 0.3943774723732622 0.6933023733149266 1.0 1.0 5 Q9Y3A6 1 +Metabolism of water soluble vitamins and cofactors 0.3359046935768319 0.3926889249701368 0.6945492515208749 1.0 1.0 34 Q96RQ3,P34896,P05165,P41440 4 +Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.3667708103828289 0.3919781226402419 0.695074378556908 1.0 1.0 9 Q9UKZ1 1 +Trna processing in the mitochondrion 0.4594290496250199 0.3891151871080585 0.6971909393868836 1.0 1.0 4 O15091 1 +Abortive elongation of hiv 1 transcript in the absence of tat 0.359766612143312 0.386873286359974 0.6988500186038475 1.0 1.0 16 P62875,P19388,P24928,P13984,P62487,Q8WX92 6 +Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0.3932618922917287 0.3861472137803282 0.6993876448041796 1.0 1.0 7 P46087,Q6PL18,P06748 3 +Rho gtpases activate formins 0.2773738685555438 0.3854003398171055 0.6999408308478463 1.0 1.0 65 Q53HL2,P35080,Q9Y6D9,Q2NKX8,O14641,O75122,P60953,P50748,Q71F23,Q9NQS7 10 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.4041434046577688 0.3799292014265785 0.7039979701889405 1.0 1.0 6 Q8NEB9,P08069,O14654 3 +Egfr downregulation 0.3469880222375811 0.3755506023321118 0.7072510203833 1.0 1.0 10 P60953,Q9Y6I3 2 +Transport of the slbp dependant mature mrna 0.3399750309990224 0.3667627489411618 0.7137959962066471 1.0 1.0 31 P78406,Q86V81,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 8 +Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.3421707862963867 0.3579704214507957 0.7203654490195477 1.0 1.0 10 Q12824,Q8TAQ2,P51532,P67870,P19784 5 +Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3423564583172017 0.3432768408701609 0.7313902017749208 1.0 1.0 12 P19784,P29992,P67870 3 +Phase 0 rapid depolarisation 0.7238468495628425 0.3422402527468773 0.7321700948643477 1.0 1.0 2 Q9HD47 1 +Activation of rac1 0.3909207250221909 0.3358107517985408 0.7370135817851691 1.0 1.0 6 O94813 1 +Josephin domain dubs 0.489746682750295 0.3303572517132019 0.74113003815795 1.0 1.0 3 P55072,P54725 2 +Pi3k akt signaling in cancer 0.3404587267570437 0.324920242181734 0.7452414363560969 1.0 1.0 14 Q9NWH9 1 +Mrna splicing 0.387500282137007 0.3197435654210031 0.7491627315941061 1.0 1.0 148 Q9NW64,P09234,Q96I25,P24928,Q86V81,P55769,Q9UMS4,Q86U42,O75643,P09012,O60306,Q13247,P19387,Q13242,O95391,Q15428,P08621,O94906,P52272,Q9BUJ2,Q9ULR0,Q9BWJ5,P33240,Q7L014,P62875,Q96BP3,Q9UNP9,O43809,Q92620,P13984,P62318,P62314,P08579,P62312,Q13435,Q9BZJ0,Q9H2H8,Q9Y3C6,Q6P2Q9,Q96DI7,P62304,Q15427,P19388,Q8WYA6,Q86XP3,Q8TBF4,O95400,Q9BUQ8,Q8IWZ8,P62487,Q15637,Q8IYB3 52 +Keratinization 0.3841080709793594 0.3140164697319536 0.7535085299661568 1.0 1.0 6 P14923,P15924,Q14126 3 +Formation of the cornified envelope 0.3841080709793594 0.3140164697319536 0.7535085299661568 1.0 1.0 6 P14923,P15924,Q14126 3 +Recognition of dna damage by pcna containing replication complex 0.3409297399610471 0.3116875399307366 0.7552779982631772 1.0 1.0 21 P41440,Q9Y2S7 2 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.3984747160124436 0.3076815344809229 0.758324671898734 1.0 1.0 5 P04439,P10321 2 +Rhog gtpase cycle 0.2943021544381963 0.2981468045375982 0.7655911201674048 1.0 1.0 39 Q07960,Q13576,P60953,O75962,Q86Y07 5 +Runx3 regulates p14 arf 0.7027434428700524 0.2951506273548905 0.7678788163549846 1.0 1.0 2 P42771 1 +Signaling by robo receptors 0.3715684200346953 0.2912973863383979 0.7708238862180885 1.0 1.0 141 P83731,Q02878,P62424,P61513,P18077,Q9Y3U8,Q9HAU5,P40123,P50914,P62701,P62280,P61586,P62269,P62857,P62750,P62841,P39019,P08708,P25788,P30050,P62277,P62854,P46776,P62081,P60953,P62753,O00487,O94813,Q8N8S7,P26373,P63173,P35080,P61247,P61353,P36578,P62861,P62910,P62847,O75122,P83881,P62899,P84098,Q9UNM6,O43347,P39023,P32969,P60866,P62917,P47914,O96013,P61313,P62244 52 +Fatty acids bound to gpr40 ffar1 regulate insulin secretion 0.6994271932469034 0.288085739118511 0.7732811086296136 1.0 1.0 2 Q01970 1 +Regulation of expression of slits and robos 0.3487450939804176 0.2861441898958279 0.7747676872097757 1.0 1.0 125 P83731,Q02878,P62424,P61513,P18077,Q9Y3U8,Q9HAU5,P50914,P62269,P62701,P62280,P62750,P62841,P62857,P39019,P08708,P05388,P25788,P30050,P62277,P35998,P61927,P46777,P40429,P62241,P62854,O43242,P62081,P62851,P46776,P62753,P62266,O00487,O94813,Q02543,P26373,P63173,P61247,P61353,P36578,Q99460,P62861,P62910,P62847,P83881,P18124,P62899,P15880,Q9Y5S9,P84098,Q9UNM6,O43347,P39023,P32969,P60866,P62917,P47914,P62263,P25398,P46781,P46778,P61254,P28072,P61313,Q15370,P62244 66 +Transcriptional regulation by small rnas 0.2954240075520207 0.2844801419581922 0.7760424500785226 1.0 1.0 38 P19387,P62875,P78406,P19388,P24928,P37198,Q9UKX7,Q8NFH5,P49790,P62487,P16104,Q5SRE5,P62805,Q9BTX1,Q8TEM1 15 +Copi mediated anterograde transport 0.243140696748667 0.2818605167033384 0.7780504656202145 1.0 1.0 55 Q96JB2,O15020 2 +Signaling by alk 0.3892830178725303 0.2806263794489714 0.7789969808639112 1.0 1.0 5 Q96ST3 1 +Base excision repair 0.3177222589005348 0.2788776901853351 0.7803386902261924 1.0 1.0 31 P62805,P41440,Q15554 3 +Rhof gtpase cycle 0.3287877756960807 0.2783645382544361 0.7807325384977308 1.0 1.0 16 Q5JTV8,Q02952,Q07960 3 +Transport of mature mrnas derived from intronless transcripts 0.3053849867871244 0.2779585125496537 0.781044206396468 1.0 1.0 35 P78406,Q86V81,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 8 +Aquaporin mediated transport 0.3722018392021886 0.2775638994461975 0.7813471476177614 1.0 1.0 6 P31323,Q99797 2 +Signaling by egfr 0.3267770094545067 0.2756897597940723 0.7827863614471509 1.0 1.0 15 P60953,P78536,Q9Y6I3 3 +Transcriptional activation of mitochondrial biogenesis 0.3254220124804281 0.2715155580680264 0.785994535373238 1.0 1.0 15 Q9BZK7,Q00059 2 +Dna damage bypass 0.3238328699256106 0.266975738768077 0.7894878409714583 1.0 1.0 26 P41440,Q9Y2S7 2 +Termination of translesion dna synthesis 0.3268536750196013 0.2659458614421328 0.7902809041592433 1.0 1.0 19 P41440 1 +Processing of capped intronless pre mrna 0.3229440301596918 0.2604963901118076 0.7944808994983628 1.0 1.0 16 Q86U42,O43809,P33240,P62318 4 +Nrage signals death through jnk 0.3406507522220791 0.2592472959606912 0.7954444412187798 1.0 1.0 8 Q9H8V3,O75962,Q14344 3 +Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0.413850123189217 0.2584458831122164 0.7960628094197792 1.0 1.0 4 P42126,P55084 2 +Attenuation phase 0.3154260028571375 0.2562812533460269 0.7977336716522705 1.0 1.0 12 P25685,P50454,P17066 3 +Factors involved in megakaryocyte development and platelet production 0.2345560058287484 0.2542521723615182 0.7993007467914415 1.0 1.0 48 O95235,O95140,O60333,P20339,Q96ST3,P60953,Q9UIJ7 7 +Mtor signalling 0.3205427953406208 0.2485221847598691 0.8037304074306091 1.0 1.0 18 Q15382 1 +Caspase activation via dependence receptors in the absence of ligand 0.4568639813712277 0.2471497481404556 0.8047923341892695 1.0 1.0 3 P42574 1 +Sumoylation of dna replication proteins 0.296682566816357 0.2467700258330012 0.8050862091180591 1.0 1.0 35 P11388,Q53HL2,P78406,Q02880,P37198,Q9UKX7,Q8NFH5,P49790,Q8TEM1,Q5SRE5,Q9BTX1,Q9NQS7 12 +Maturation of sars cov 1 spike protein 0.3759650184456772 0.2436607894535961 0.8074935436439452 1.0 1.0 5 Q13724 1 +Bbsome mediated cargo targeting to cilium 0.3349441256418012 0.2430249653604789 0.8079860575497995 1.0 1.0 8 P48643,P78371,Q9H0F7,Q9NQ48,P50990,P49368,P17987 7 +Folding of actin by cct tric 0.3349441256417947 0.2430249653604612 0.8079860575498132 1.0 1.0 8 Q99832,P48643,P40227,P78371,P50990,P49368,P17987 7 +Cdc42 gtpase cycle 0.2907651664725323 0.2384848471909463 0.8115050665504799 1.0 1.0 36 Q9Y5S2,O75962,Q13576,Q07960 4 +Negative regulation of the pi3k akt network 0.3140442997997762 0.2382863049249076 0.8116590425601597 1.0 1.0 15 P31749,Q9NWH9 2 +Viral messenger rna synthesis 0.2896426157137636 0.2347516367103468 0.8144015070961064 1.0 1.0 36 P62875,P78406,P19388,P24928,P37198,P13984,Q9UKX7,Q8NFH5,P49790,P62487,Q5SRE5,Q9BTX1,Q8TEM1 13 +Gap filling dna repair synthesis and ligation in gg ner 0.3153506326958114 0.2315539813543818 0.8168844536172213 1.0 1.0 20 P41440 1 +Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3150443103640897 0.2309676188887071 0.8173399582992045 1.0 1.0 22 P41440 1 +Pink1 prkn mediated mitophagy 0.3013976401017362 0.2294796187375634 0.8184961598889564 1.0 1.0 10 Q9NS69,O95140 2 +Initiation of nuclear envelope ne reformation 0.3118996868805792 0.22647089050103 0.8208351971273247 1.0 1.0 17 Q99986,Q86Y07 2 +Pcna dependent long patch base excision repair 0.3134789459257273 0.2264214771568163 0.8208736252757771 1.0 1.0 20 P41440 1 +Disinhibition of snare formation 0.663852879107625 0.2183311518430575 0.8271711042121088 1.0 1.0 2 O00186 1 +Translation 0.4392348508991249 0.218092163308958 0.8273573032239101 1.0 1.0 221 Q7Z7F7,Q5T653,P61513,P82914,Q9UI10,P62857,Q9BYD6,Q9UGM6,P46776,P62081,Q9BW92,P62847,P82675,Q8N983,Q5ST30,P47914,Q9NX20,P62244,P18077,Q9Y3U8,P50914,P62701,P62280,Q9Y3D3,P39019,Q9H2U2,P82912,Q9Y3D9,Q9Y285,Q5T160,P61247,P61353,O43324,P84098,Q5JTZ9,P39656,P61011,P61313,Q8N5N7,Q9H2W6,Q8TAE8,Q7L2H7,P04844,Q02878,P62424,Q9Y5M8,Q15046,P08708,P30050,Q13347,O75616,P62753,P62854,Q15031,P36578,P62861,P62910,P83881,P62899,P49406,P83731,P62269,P62750,P62841,Q15056,P62277,Q96EY7,Q9NP81,P26373,P63173,Q9Y2R9,P60468,P39023,P32969,P60866,P62917,P82664,Q96RP9,Q92665 79 +Rho gtpases activate nadph oxidases 0.3232463160801249 0.2117983289630006 0.832264372243849 1.0 1.0 8 Q16539 1 +Rac2 gtpase cycle 0.2784612984068151 0.2108016275132198 0.8330420685095461 1.0 1.0 37 O75962,P60953,Q07960,Q86Y07 4 +Metabolism of rna 0.35277818048278 0.2103140436667649 0.8334225751409197 1.0 1.0 474 P22087,P61513,Q86V81,P55769,Q969Y2,Q2NL82,Q68CQ4,P62857,Q9Y3Y2,Q86W42,O95391,Q15428,P08621,Q8TCT8,O94906,P46087,P52272,P46776,P62081,Q96B26,Q9BWJ5,Q5SRE5,Q13868,Q9NR30,Q96BP3,Q9UNP9,Q99848,P31749,O15213,P62847,Q99547,P62312,P08579,Q99575,P47914,Q15427,Q8WYA6,Q8TBF4,Q9BUQ8,Q9UKZ1,Q9NW13,Q9NXG2,P62244,Q9NW64,Q14137,O00541,P18077,Q9Y3U8,P24928,P37198,P50914,P62701,P62280,P49790,P39019,Q13247,Q9Y4W2,Q9Y6M1,O43709,Q9ULR0,P57678,O00487,O75175,P61247,Q16539,P61353,P62318,P62314,Q9H974,Q9Y2L1,P84098,Q9UNM6,O75152,Q6P2Q9,Q96DI7,Q9Y3A2,O95400,Q8NFH5,Q8IWZ8,P62487,P61313,Q8IY81,Q8TEM1,Q02878,P62424,Q9BVJ6,Q9HAU5,Q9NY93,Q9UKX7,Q8TEA1,Q9UMS4,Q5VV42,Q86U42,P09012,O00567,O60306,P08708,P25788,P30050,Q13601,P82979,P62854,P62753,Q9BTX1,Q9NPF4,Q9NXH9,Q9Y6V7,O43809,P13984,P36578,P62861,P62910,P83881,P62899,Q9BZJ0,Q9H2H8,Q9UJA5,Q9Y3C6,Q5RKV6,Q8NI27,Q9H9L3,Q9H583,P83731,P09234,P62269,P62750,P62841,Q9BY77,Q9H0A0,P62277,Q9BUJ2,P33240,O60832,P26373,P62875,P63173,Q12788,Q92620,Q9H0S4,Q9UNQ2,Q9Y2P8,P39023,P32969,P60866,P62917,P78406,Q86XP3,Q13895,Q15637,Q06265 150 +Gene silencing by rna 0.2349770665781782 0.2063060447242167 0.8365518570923813 1.0 1.0 46 P19387,P62875,P78406,P19388,P24928,P37198,Q9UKX7,Q8NFH5,P49790,P62487,P16104,Q5SRE5,P62805,Q9BTX1,Q8TEM1 15 +Costimulation by the cd28 family 0.3003118042635649 0.2061497703180516 0.8366739225144337 1.0 1.0 14 P31749 1 +Signaling by fgfr 0.3045221934736788 0.2053872185341732 0.8372696055505258 1.0 1.0 24 P62875,Q06124,P24928,P19388,P13984,P52272,P62487,Q01085,P31483 9 +Signaling by fgfr2 0.3045221934736788 0.2053872185341732 0.8372696055505258 1.0 1.0 24 P62875,Q06124,P24928,P19388,P13984,P52272,P62487,Q01085,P31483 9 +Lagging strand synthesis 0.3039323309016501 0.2017705254682931 0.8400961248834036 1.0 1.0 20 P41440 1 +Slc mediated transmembrane transport 0.3011092370644169 0.1971958978964491 0.8436742405959385 1.0 1.0 18 P35613,Q8TB61 2 +Rhoj gtpase cycle 0.2986613299404135 0.1927666306783679 0.8471417381615096 1.0 1.0 25 Q9Y5S2,O75962,Q07960 3 +Cytosolic trna aminoacylation 0.2971773091878394 0.186327468777699 0.8521879676666801 1.0 1.0 23 O43776,P41252,P26639,P23381,Q9Y285,P14868,P26640,O43324,Q15046 9 +Transcription coupled nucleotide excision repair tc ner 0.2166416142995178 0.1837387219052609 0.854218430330073 1.0 1.0 48 P62875,Q9Y2S7,P18887,Q9UNP9,P24928,P19388,P05114,P28340,Q9UMS4,P49005,P62487,Q9ULR0,P41440,O60306,P35251 15 +Estrogen dependent gene expression 0.2852025696735631 0.1775158132991614 0.8591032452657881 1.0 1.0 30 Q15185,P19387,P62875,P19388,P24928,P13984,O60216,Q9HCL2,P16104,P62487,P62805 11 +Infectious disease 0.1808195632837843 0.1771604179678646 0.8593823857039569 1.0 1.0 356 P05141,P61513,O14641,P62857,Q15022,P43487,Q00403,O15143,P46776,P62081,Q5SRE5,Q9NWH9,P62847,P04439,P46977,Q99720,P47914,Q8TBF4,Q9BZK7,P62244,P09874,P18077,Q9Y3U8,P24928,O43633,P37198,P50914,P62701,P62280,P49790,P39019,Q8NEB9,Q8WX92,P62805,P46734,P60953,O00487,Q16706,P61160,Q13330,P61247,Q14839,Q16539,P61353,P53680,P20339,Q96FJ2,Q9H444,P78536,P84098,Q9UNM6,O75475,Q8NFH5,P39656,P62487,P61313,Q8TEM1,P04844,Q02878,P62424,Q9UKX7,Q86U42,Q13724,P08708,P25788,P30050,P59998,O15144,P62854,P62753,Q9BTX1,P13984,P36578,P62861,P62910,P83881,P62899,P17096,P54709,P83731,P62269,P62750,P62841,O00159,P62277,P26373,P62875,P63173,Q10567,P39023,P32969,P60866,P62917,P78406,Q9Y3E5 95 +Mitochondrial fatty acid beta oxidation 0.2888135641831202 0.1764958730973919 0.8599043905826753 1.0 1.0 15 P42126,P05165,P22033,P55084 4 +Interactions of vpr with host cellular proteins 0.2751398286735468 0.1760700900218738 0.8602388785140835 1.0 1.0 34 P05141,P78406,P37198,O75475,P17096,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 10 +Processing of capped intron containing pre mrna 0.3845407576426321 0.174233081355565 0.861682287974568 1.0 1.0 190 Q9NW64,P09234,Q96I25,P24928,Q86V81,P37198,P55769,Q9UKX7,P49790,Q9Y3Y2,Q9UMS4,Q9BY77,Q86U42,O75643,P09012,O60306,Q86W42,Q13247,P19387,Q13242,O95391,Q15428,P08621,O94906,P82979,P52272,Q9BUJ2,Q9ULR0,Q9BWJ5,Q5SRE5,P33240,Q9BTX1,Q7L014,P62875,Q96BP3,Q9UNP9,O43809,Q92620,P13984,P62318,P62314,P08579,P62312,Q13435,Q9BZJ0,Q9H2H8,O00148,Q9Y3C6,O75152,Q6P2Q9,Q96DI7,P62304,Q15427,P19388,P78406,Q8WYA6,Q86XP3,Q8TBF4,O95400,Q8NFH5,Q9BUQ8,Q8IWZ8,P62487,Q8NI27,Q15637,Q8IYB3,Q8TEM1 67 +Cellular responses to stimuli 0.2636278902017823 0.1704422519974509 0.8646623459460587 1.0 1.0 332 P21283,P61513,P62857,Q15382,Q15022,O43909,O60884,P31689,P46776,P62081,Q96B26,Q5SRE5,P07305,O14548,Q13868,P62847,P19784,P47914,Q8N122,Q9BZK7,Q9HCU5,P62244,P16403,P18077,Q9Y3U8,P37198,P50914,Q15554,P62701,P62280,P49790,P39019,P62805,P46734,P10412,P09669,O00487,P30048,Q9BSH4,P61247,Q16539,P61353,Q96FJ2,Q9Y2L1,P84098,Q9UNM6,Q9Y2Q5,P25685,Q8NFH5,P67870,P61313,P50454,Q8TEM1,Q02878,P62424,Q9UKX7,Q9Y5M8,P08708,P25788,P30050,Q06210,P62854,O60934,P62753,P62266,Q9BTX1,P17066,P36578,P62861,P62910,P83881,P62899,Q5RKV6,O43819,P04179,P17096,P83731,P16402,P62269,P62750,P62841,Q96ST3,P62277,P42771,P26373,P20674,P63173,P39023,P32969,P60866,P62917,P78406,Q6IAA8,Q9Y5K8,Q06265 95 +Unfolded protein response upr 0.2374213713459183 0.166827417055619 0.8675058452983957 1.0 1.0 43 O43909,Q13868,Q5RKV6,Q06265,Q06210,P20042,Q9HCU5,Q96B26,Q9Y5M8,Q9Y2L1 10 +Rna polymerase ii transcription 0.2164975743400432 0.1648496630994816 0.8690623132387336 1.0 1.0 312 Q12824,O60244,Q86V81,Q96ST3,Q9Y3Y2,Q6PL18,Q9BY77,P62805,Q15382,Q86W42,Q13247,Q9ULK4,P09669,O95391,P42771,Q8N201,O60934,P42858,P33240,O14548,P20674,O75175,P62875,Q9BSH4,O43809,Q9NWH9,Q16539,P13984,P31749,P78356,Q9HAF1,P54132,O75152,O43819,Q9UHY1,P04179,Q9BZK7,Q9HCL2,Q9UKZ1,Q8NI27 40 +Ephb mediated forward signaling 0.2835516640882704 0.1632190251875397 0.8703459871396906 1.0 1.0 16 O15143,P61160,O15144,P61586,P60953 5 +Pi metabolism 0.2841117752950506 0.1594893461782542 0.8732833514015774 1.0 1.0 19 Q9UBF8,P20339,P78356,Q9NTJ5,P20338 5 +Synthesis of pips at the golgi membrane 0.2860510558191744 0.1590285219571536 0.8736464025052575 1.0 1.0 9 Q9NTJ5,Q9UBF8 2 +Slc transporter disorders 0.2723528271034484 0.1588731761458988 0.8737687945816179 1.0 1.0 32 P78406,P08195,P37198,P35613,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 9 +Developmental biology 0.3143968418575256 0.1522984289121602 0.8789515640128238 1.0 1.0 267 P61513,O60244,P40123,Q13740,P62857,O15020,Q14126,Q15022,P11047,O15143,P46776,P62081,Q9BPU6,Q8N8S7,P35080,Q9NWH9,P31749,P62847,O75962,P19784,O43347,P47914,Q9BZK7,P62244,Q13503,P18077,Q9Y3U8,P24928,P50914,P62701,P62280,P61586,P46939,P39019,P62805,Q9ULK4,P60953,O00487,O94813,P14923,P35241,P61160,P61247,Q15291,P61353,P53680,Q16539,O75122,P84098,Q9UNM6,O96013,P62487,P67870,P61313,Q02878,P62424,Q9HAU5,P08708,P25788,P30050,P59998,Q06124,O15144,P62854,P62753,P36578,P62861,P62910,P83881,P62899,P83731,P62269,P62750,P62841,P62277,P26373,P62875,P63173,P39023,P32969,P60866,P62917 82 +Deadenylation dependent mrna decay 0.2399089101271784 0.1520338241823201 0.8791602578964057 1.0 1.0 41 P62312,Q9UKZ1,Q13868 3 +Anti inflammatory response favouring leishmania parasite infection 0.2740997734147513 0.1506273908411238 0.880269653144006 1.0 1.0 14 Q16539,P78536 2 +Formation of the early elongation complex 0.2778827106842005 0.1492103990381602 0.8813876146063395 1.0 1.0 18 P62875,P19388,P24928,P13984,P62487,Q8WX92 6 +Formation of tc ner pre incision complex 0.2748126306739814 0.147278203883072 0.8829124356448825 1.0 1.0 27 P62875,Q9UNP9,P24928,P19388,P05114,Q9UMS4,P62487,Q9ULR0,O60306 9 +Sumoylation of chromatin organization proteins 0.2634702542052742 0.1463631771274741 0.883634694616896 1.0 1.0 33 Q15022,P78406,P37198,Q8NFH5,P49790,Q5SRE5,P62805,Q9BTX1,Q8TEM1 9 +Chl1 interactions 0.6186312933373475 0.1463281820003789 0.8836623192794435 1.0 1.0 2 P05556 1 +Dual incision in gg ner 0.2741424970110752 0.1411074330446132 0.8877850716884883 1.0 1.0 23 P41440 1 +Nervous system development 0.3146902519525936 0.1392491673202261 0.889253257027419 1.0 1.0 219 P83731,Q02878,P62424,P61513,P18077,Q9Y3U8,Q9HAU5,P40123,P50914,P62701,P62280,Q13740,P61586,P62857,P46939,O15020,P39019,P08708,P11047,P25788,O15143,P30050,P62277,P59998,Q06124,O15144,P62854,P46776,P62081,P60953,P62753,O00487,O94813,Q9BPU6,P62269,Q8N8S7,P26373,P35241,P62750,P35080,P61160,P63173,P61247,P62841,Q9NWH9,Q16539,P61353,P53680,P36578,P62861,P62910,P62847,O75122,P83881,P62899,O75962,P19784,P84098,Q9UNM6,O43347,P39023,P32969,P60866,P62917,P47914,O96013,P67870,P61313,P62244 69 +Leishmania infection 0.2443899007643589 0.1386991810067195 0.889687865306634 1.0 1.0 38 O00159,Q16539,O14641,O15144,Q9Y3E5,P60953,P78536 7 +Rac3 gtpase cycle 0.2470160215237155 0.1374596203395356 0.8906675080124364 1.0 1.0 37 O75962,Q07960,Q86Y07 3 +Diseases of programmed cell death 0.2686338679932323 0.1369438405789241 0.8910751854766594 1.0 1.0 27 Q15022,Q07021,P17655,P42771,P04179,P62805 6 +Mitophagy 0.2643313632772471 0.1369192013726488 0.8910946612724271 1.0 1.0 13 Q9NS69,P19784,O95140,Q8N4H5 4 +Mitochondrial iron sulfur cluster biogenesis 0.35780345612571 0.1367280205120286 0.8912457803606715 1.0 1.0 4 P22570,Q9H1K1 2 +Hsf1 dependent transactivation 0.2676034650889249 0.1352827161400511 0.8923883499701353 1.0 1.0 16 Q15185,Q8N122,P17066,P25685,P50454 5 +Galactose catabolism 0.6092854989448233 0.1338170509233578 0.8935472437778806 1.0 1.0 2 Q96G03 1 +Metabolism of amino acids and derivatives 0.3109411477060231 0.132354729775616 0.8947037199895482 1.0 1.0 189 P83731,P00505,Q02878,P62424,P61513,P18077,Q9Y3U8,P62269,P50914,Q9UBX3,P62701,P62280,P62750,P62841,P62857,P39019,Q15046,P30038,P08708,P25788,P10515,P30050,P26440,P62277,Q02218,P62854,P46776,P62081,P62753,P08559,O00487,Q92947,P26373,P52758,P63173,P09622,P61247,Q8TD30,P61353,P36578,P78330,P62861,P62910,P62847,P83881,O43324,P62899,P25325,P84098,P36957,Q9UNM6,P39023,P32969,P60866,O15382,P62917,Q96RQ3,P47914,P34896,P12532,P61313,P08195,P62244 63 +Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.2575011578863613 0.1322948575774268 0.894751074685119 1.0 1.0 11 Q96ST3,P62805,Q15291,P16104 4 +Nucleotide excision repair 0.1963626192660164 0.1244227595501793 0.90098055385069 1.0 1.0 57 P62875,Q9Y2S7,P18887,P09874,Q9UNP9,P24928,P19388,P05114,P28340,Q9UMS4,P62487,Q9ULR0,P41440,O60306,P35251 15 +Processing of intronless pre mrnas 0.2560673935016889 0.1223386637591815 0.9026308127048774 1.0 1.0 14 O43809,P33240 2 +Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.2778616732105115 0.1175342864217028 0.9064366756882548 1.0 1.0 8 Q13573,P09874,O75376,P27361,P28482,Q13547,Q93008 7 +Glycogen synthesis 0.3054381010833457 0.1171196000810776 0.9067652780073976 1.0 1.0 6 Q04446 1 +Eph ephrin signaling 0.2493582792204464 0.1163386181547996 0.907384180531826 1.0 1.0 30 O95782,O15143,P61160,P59998,P53680,O15144,P61586,P60953 8 +Intra golgi and retrograde golgi to er traffic 0.2344700101044641 0.1152833366366425 0.9082205457340852 1.0 1.0 101 Q16706,O75396,P53365,Q7Z6M1,Q9NP72,Q96JB2,O60333,P82094,Q9H9E3,P62820,Q5VZE5 11 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.2551776495446968 0.1146459028248422 0.9087257943645995 1.0 1.0 23 P41440 1 +Transcriptional regulation by tp53 0.1716812520017897 0.1138977181887579 0.9093188744185978 1.0 1.0 129 O14548,P20674,O75175,P62875,P54132,P09669,Q9BSH4,O43819,P42771,Q6IAA8,Q16539,P13984,P31749,O60934,P78356,Q9UKZ1,Q9HAF1,Q15382 18 +Trna processing in the nucleus 0.215698214514183 0.1136711358675312 0.9094984944216692 1.0 1.0 41 Q9Y3I0,P78406,Q99575,Q9Y224,P37198,P78346,Q9UKX7,Q8NFH5,P49790,Q5SRE5,P33240,Q9BTX1,Q8TEM1 13 +Rho gtpase effectors 0.1927398731965165 0.1128403711058129 0.9101571112111771 1.0 1.0 125 P62140,Q53HL2,P35080,Q9Y6D9,Q2NKX8,Q16539,O14641,O15144,Q13576,P60953,O75122,P50748,P62805,Q9NQS7 14 +Signaling by receptor tyrosine kinases 0.1824166731604251 0.1119798421694967 0.9108393896504604 1.0 1.0 122 P21283,O14654,P24928,P61586,Q96ST3,Q8NEB9,Q8WX92,P31483,P20338,P11047,Q9Y6I3,P52272,P60953,Q01085,P08069,P14923,P62875,Q9NWH9,Q07812,Q16539,P53680,P13984,P31749,P78536,Q9UBC2,P62330,Q9Y5K8 27 +Establishment of sister chromatid cohesion 0.2740352229929334 0.111545675592315 0.91118364767974 1.0 1.0 8 Q9NTI5,O60216,Q14683 3 +Asparagine n linked glycosylation 0.1766407323012652 0.1114160759244017 0.9112864126845934 1.0 1.0 120 O60762,Q16706,O75340,O75396,P04844,Q96JB2,Q14165,Q9Y673,Q13724,O95394,Q8NFW8,O15020,Q9H9E3,Q5H9R7,P62820 15 +Hats acetylate histones 0.2516305130676039 0.1103320601085102 0.9121460321779176 1.0 1.0 21 Q9NPF5,P62805 2 +Mitotic prophase 0.1868061579506501 0.1088633480546009 0.9133108778327584 1.0 1.0 61 Q99986,P78406,P37198,P62820,Q8NFH5,P49790,P61019,Q5SRE5,O95347,P62805,Q9BTX1,Q86Y07,Q8TEM1 13 +Mitochondrial protein import 0.2301664229250897 0.1078828350043235 0.9140886333267044 1.0 1.0 35 Q9NS69,P10809,P08574,P12235,O75431,Q9Y5J9,O60220,Q99595,O14925,Q99798,Q8N4H5,Q9Y5J7,P51553,P38646,O75390 15 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.5860717515827529 0.1061898029964126 0.9154317612320056 1.0 1.0 2 Q15005 1 +Synthesis secretion and deacylation of ghrelin 0.5860717515827529 0.1061898029964126 0.9154317612320056 1.0 1.0 2 Q15005 1 +Glucose metabolism 0.1803612273637157 0.1051337168219856 0.9162697053917874 1.0 1.0 60 P00505,P78406,P04406,P37198,Q9UBX3,P11498,Q9UKX7,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 12 +Activation of gene expression by srebf srebp 0.2447617471261603 0.1037236128227846 0.9173886874018022 1.0 1.0 19 Q9BZK7 1 +Transport to the golgi and subsequent modification 0.1888198741029714 0.1034898242852309 0.917574225174952 1.0 1.0 80 Q96JB2,Q5H9R7,P62820,O15020 4 +Er to golgi anterograde transport 0.1851131344242283 0.1027847095496952 0.91813384099572 1.0 1.0 75 Q96JB2,P62820,O15020 3 +Rhod gtpase cycle 0.2380281428228846 0.1018342162610779 0.9188882661679734 1.0 1.0 28 Q5JTV8,Q07960,Q86Y07 3 +Translation of sars cov 2 structural proteins 0.2404439509775097 0.0997244304305302 0.9205631045428186 1.0 1.0 19 Q16706,P04844 2 +Rmts methylate histone arginines 0.238049010491681 0.0976619686057936 0.9222007157972608 1.0 1.0 19 P62805 1 +Cobalamin cbl vitamin b12 transport and metabolism 0.3719688613574934 0.0954806185202399 0.9239330841009092 1.0 1.0 3 P22033 1 +Defects in cobalamin b12 metabolism 0.3719688613574934 0.0954806185202399 0.9239330841009092 1.0 1.0 3 P22033 1 +Glycolysis 0.1276136892433237 0.092294192542644 0.9264643023572032 1.0 1.0 49 P78406,P04406,P37198,Q9UKX7,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 9 +Nuclear envelope breakdown 0.1794446570922621 0.0907287059524805 0.9277081606425832 1.0 1.0 41 Q99986,P78406,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q86Y07,Q8TEM1 9 +Resolution of abasic sites ap sites 0.2227462839465466 0.0903218821285198 0.928031431795204 1.0 1.0 27 P41440 1 +Dna strand elongation 0.2188963001999587 0.0901398474142781 0.9281760844302542 1.0 1.0 29 P41440 1 +Global genome nucleotide excision repair gg ner 0.1712240539965838 0.0888378787357384 0.9292107538102412 1.0 1.0 41 P41440 1 +Scavenging by class a receptors 0.3664053075995215 0.0888323008361674 0.929215186803767 1.0 1.0 3 Q5KU26,P27797 2 +Regulation of glucokinase by glucokinase regulatory protein 0.2191609956362959 0.0884572254917739 0.9295132801317704 1.0 1.0 27 P78406,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 7 +Snrnp assembly 0.1616897387260029 0.0884498579115763 0.9295191356584902 1.0 1.0 42 P78406,P37198,P62318,Q8NFH5,P49790,P62314,P57678,Q5SRE5,Q9BTX1,Q8TEM1 10 +Caspase activation via extrinsic apoptotic signalling pathway 0.2989316168240393 0.0874764193797016 0.9302928281777678 1.0 1.0 5 P42574 1 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.2186214314219998 0.0867597508571762 0.9308624811004308 1.0 1.0 25 P60953,P14174 2 +Interactions of rev with host cellular proteins 0.1939587734904433 0.0860198554590957 0.9314506333533588 1.0 1.0 34 P43487,P78406,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 8 +Condensation of prometaphase chromosomes 0.2344215059461296 0.0844593353753797 0.9326912329457626 1.0 1.0 9 O95347,P19784 2 +Sumoylation of sumoylation proteins 0.2075470584959854 0.084432783961353 0.9327123425071489 1.0 1.0 28 P78406,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 7 +Tyrosine catabolism 0.5640639131745457 0.0843799500387213 0.9327543479788478 1.0 1.0 2 P16930 1 +Export of viral ribonucleoproteins from nucleus 0.2031685401149463 0.0838433602764608 0.933180972851652 1.0 1.0 29 P78406,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 7 +Sumoylation of ubiquitinylation proteins 0.2055893374747646 0.0837780321113229 0.9332329144403624 1.0 1.0 28 P78406,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 7 +Other interleukin signaling 0.3218299900041038 0.0834931238609906 0.9334594446674228 1.0 1.0 4 P42574,Q12846 2 +Antigen presentation folding assembly and peptide loading of class i mhc 0.2136678140197085 0.0828918606077082 0.9339375260627338 1.0 1.0 14 P04439,Q03518,P10321 3 +Raf independent mapk1 3 activation 0.2840325988530061 0.0826829093801368 0.9341036746735628 1.0 1.0 6 Q06124,P06493,P27361,P28482,Q02750 5 +Sumoylation of rna binding proteins 0.1899067322774202 0.0822937534423183 0.9344131216045192 1.0 1.0 31 P78406,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 7 +Beta oxidation of hexanoyl coa to butanoyl coa 0.3206480248795125 0.0820676874224239 0.9345928881230938 1.0 1.0 4 P55084 1 +Beta oxidation of lauroyl coa to decanoyl coa coa 0.3206480248795125 0.0820676874224239 0.9345928881230938 1.0 1.0 4 P55084 1 +Interleukin 12 signaling 0.2008073562532348 0.0816023430974542 0.9349629379888612 1.0 1.0 27 P60953,P14174 2 +Nuclear import of rev protein 0.1808219421217442 0.0808436739636761 0.9355662749167803 1.0 1.0 31 P78406,P37198,Q8NFH5,P49790,Q5SRE5,Q9BTX1,Q8TEM1 7 +Interleukin 12 family signaling 0.1790465403002937 0.0798444865826795 0.9363609420686032 1.0 1.0 30 P60953,P14174 2 +Vxpx cargo targeting to cilium 0.2022455156343131 0.0791290571089337 0.9369299717390498 1.0 1.0 10 Q9NV70 1 +Regulation of cholesterol biosynthesis by srebp srebf 0.1947523982114286 0.0787757652918375 0.9372109806255304 1.0 1.0 25 Q9BZK7 1 +Rho gtpases activate pkns 0.1951835814746708 0.0771107108449974 0.9385354723505206 1.0 1.0 22 P62805 1 +Downregulation of smad2 3 smad4 transcriptional activity 0.2776939329912494 0.0740515495434243 0.9409693672171436 1.0 1.0 6 O75376,P09874,Q13573,Q13547,Q93008 5 +Ion transport by p type atpases 0.2217464679952766 0.0740274490245793 0.9409885440147971 1.0 1.0 9 P20020,P05023,P54709,Q13555,Q9HD20,P16615 6 +Hsf1 activation 0.184896695966491 0.0719730805848663 0.9426233308588112 1.0 1.0 15 P25685,P50454,P17066 3 +Association of tric cct with target proteins during biosynthesis 0.1663132384126002 0.0705822798818251 0.9437302138398612 1.0 1.0 18 Q99832,P50991,Q9BUR4,P48643,P40227,Q15477,P61962,P04637,Q9Y2T2,P51784,P17987,Q9H0D6,P49368,P50990,P40763,O00567,P78371 17 +Signaling by ntrk3 trkc 0.3069660662749039 0.0669885328758404 0.946590832133793 1.0 1.0 4 Q07812 1 +Transcriptional regulation by e2f6 0.2090634441087558 0.0660659421016155 0.9473253258546428 1.0 1.0 9 Q15022,Q9UBK9,P45973,P38398,O14757,Q96KQ7,Q16576,Q13185 8 +Syndecan interactions 0.2995115643768763 0.0598363509145271 0.952285973589647 1.0 1.0 4 Q9Y296 1 +Inositol phosphate metabolism 0.2202752309829297 0.0559314644632115 0.9553964050377453 1.0 1.0 8 Q9BW91 1 +Molybdenum cofactor biosynthesis 0.5260777811275126 0.0559136658355494 0.9554105840992912 1.0 1.0 2 Q9Y697 1 +Protein methylation 0.2353496111937489 0.0493272149277167 0.9606585315355772 1.0 1.0 7 P38117,P15880 2 +Gaba synthesis release reuptake and degradation 0.3880012059089511 0.0182887068071098 0.9854085366237456 1.0 1.0 2 P11142 1 +Synthesis of pi 0.3705155260777766 0.0173650834426184 0.9861453643295256 1.0 1.0 2 O14735 1 +Atf6 atf6 alpha activates chaperones 0.3662948447392208 0.0171943467660875 0.9862815721509608 1.0 1.0 2 P27797 1 +Atf6 atf6 alpha activates chaperone genes 0.3662948447392208 0.0171943467660875 0.9862815721509608 1.0 1.0 2 P27797 1 +Rhot1 gtpase cycle 0.3578534820621042 0.0169027884747986 0.9865141682044274 1.0 1.0 2 Q8IXI2 1 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b896086fe878932987cbb35024a661e8e353f5b9 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective b4galt1 causes b4galt1 cdg cdg 2d", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 activates ptk6 signaling", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr3a mediated il10 synthesis", "Fertilization", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interaction with cumulus cells and the zona pellucida", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pou5f1 oct4 sox2 nanog repress genes related to differentiation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 promotes hif1a stabilization", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of gene expression in beta cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Release of hh np from the secreting cell", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "Runx3 regulates yap1 mediated transcription", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 hd domain mutants in cancer", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 dependent activation of irf3 irf7", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Yap1 and wwtr1 taz stimulated gene expression", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APC", "APEH", "APEX1", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRAP", "BRCA1", "BRD2", "BRD4", "BSG", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CDX2", "CENPE", "CENPI", "CENPU", "CEP250", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLINT1", "CLNS1A", "CLSPN", "CLTA", "CLTC", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COG4", "COG7", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTL", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHMT2", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM49B", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNTA", "FNTB", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "IKBKG", "ILF2", "ILK", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRPPRC", "LRRC1", "LRRC41", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "METTL3", "MFAP1", "MFN1", "MFN2", "MGAT1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO6", "NAA16", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFKB1", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNT", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA5", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIP4K2B", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RNASET2", "RNF14", "RNF20", "RNF220", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC38A2", "SLC3A2", "SLC6A15", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX18", "STX4", "STX6", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", 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file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d6c99f451e1e2a4df458cbd4aee31c4f23fb3114 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..324f7b3baf9a8a7f31072a07849a98d3e6088aeb --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,185 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytoplasmic ribosomal proteins 0.4989970386437868 2.3158483529282567 0.0205665500924137 0.999996743442791 0.7405079523469146 75 P83731,Q02878,P62424,P18077,P62269,Q9Y3U8,P61513,P50914,P62841,P62750,P62280,P62701,P62857,P39019,P08708,P05388,P30050,P62277,P46777,P40429,P61927,P62241,P62854,P62753,P62266,P62851,P62081,P46776,Q02543,P26373,P63173,P61247,P61353,P36578,P62861,P62910,P62847,P18124,P83881,P62899,P15880,P84098,P39023,P60866,P62917,P32969,P49406,P47914,P62263,P25398,P46781,P46778,P61254,P61313,P62244 55 +Biotin metabolism including iems 0.7982316977624531 2.171904754054073 0.0298628478236033 0.9999999901247744 0.7405079523469146 7 Q96RQ3,P05165 2 +Follicle stimulating hormone fsh signaling pathway 0.685246923469148 2.05654403234154 0.0397301065862243 0.9999999999802696 0.7405079523469146 10 P31749,Q15382 2 +Hostpathogen interaction of human coronaviruses apoptosis 0.8234761617380788 2.050482700799834 0.0403173502182778 0.999999999986398 0.7405079523469146 5 P42574,Q16539,Q07820,P31749 4 +Endoplasmic reticulum stress response in coronavirus infection 0.7275287246873933 1.9785990421084303 0.0478611675994835 0.999999999999888 0.7461433307816923 8 Q96QC0,Q12972,Q15435 3 +Angiogenesis 0.8382779495108115 1.8737017905198128 0.0609715390140133 1.0 0.8126948888142176 4 P31749 1 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.7530994815802197 1.8651956050265024 0.0621539913773752 1.0 0.8126948888142176 6 Q15382 1 +Mitochondrial complex i assembly model oxphos system 0.5840433641840721 1.840685601947669 0.0656676450811297 1.0 0.8126948888142176 30 O95139,P03915,O75438,O43676,Q8IUX1,O95168,O75380,P28331,Q9NPL8,Q96CU9,Q9P0J0 11 +Regucalcin in proximal tubule epithelial kidney cells 0.7181002395660855 1.816999991809335 0.0692171145998856 1.0 0.8126948888142176 7 P42574,P31749,Q8NE86 3 +Erk pathway in huntingtons disease 0.8092671118027688 1.7574896905894 0.0788343775548583 1.0 0.8295418476715958 4 P42858 1 +Cell migration and invasion through p75ntr 0.6963289442307348 1.7185950712484996 0.0856881297664529 1.0 0.8295418476715958 7 P31749 1 +Photodynamic therapyinduced ap1 survival signaling 0.6149547278698042 1.695198124988041 0.0900378424984951 1.0 0.8295418476715958 10 Q07820,P42771,Q16539,P46734 4 +Valproic acid pathway 0.7185158297698926 1.606675681821318 0.1081255308784185 1.0 0.8295418476715958 5 P26440,P55084 2 +Electron transport chain oxphos system in mitochondria 0.3892387711536748 1.595884327951655 0.1105146211536172 1.0 0.8295418476715958 55 O14548,P20674,P05141,P56134,P19404,O75438,O43676,P09669,O95139,O95168,O75380,P28331,P03915,Q9UDW1,Q9UII2,O14949 16 +Proteoglycan biosynthesis 0.7030974708276514 1.5402235348555122 0.1235058750462725 1.0 0.8593059573410112 5 O43909 1 +Neural crest cell migration during development 0.5843952365946246 1.5353887366007215 0.1246883687574971 1.0 0.8593059573410112 10 P31749 1 +Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma 0.6554231374621587 1.5318367650628562 0.1255627210843575 1.0 0.8593059573410112 7 Q9P0M6,O75367 2 +Nonalcoholic fatty liver disease 0.3838241731973534 1.5173667513822011 0.1291741135665747 1.0 0.8593059573410112 56 O75438,O43676,P42574,Q9UDW1,P19404,P09669,P60953,P28331,O14548,P20674,Q86Y39,Q07812,O75380,P31749,P08574,O95139,O95168,Q9P0J0,O14949 19 +Hematopoietic stem cell gene regulation by gabp alphabeta complex 0.7431974269177574 1.489280508066536 0.1364135183080133 1.0 0.8593059573410112 4 Q15554 1 +Krebs cycle disorders 0.6907191217483237 1.4867031886610282 0.1370932201678916 1.0 0.8593059573410112 5 P36957,Q9P2R7 2 +Notch signaling 0.6433892775728182 1.4765181585285556 0.1398048441947739 1.0 0.8673606660247197 7 O14641 1 +Immune response to tuberculosis 0.7345478816503841 1.4538879820354964 0.1459773652780209 1.0 0.8875423808903674 4 O60244 1 +Eukaryotic transcription initiation 0.561040639799157 1.4000696796912042 0.1614924535581372 1.0 0.9532758423625964 14 P19387,Q00403,Q9GZS1,O15160,P19388,P24928,P13984,O95602,P62487,Q9H9Y6 10 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.5787574144541858 1.380684738665939 0.1673759157362844 1.0 0.9619814353526356 9 P31749 1 +Regulation of apoptosis by parathyroid hormonerelated protein 0.622575902341755 1.3805567876528153 0.1674152776732633 1.0 0.9619814353526356 7 P31749,Q07820 2 +Cholesterol biosynthesis with skeletal dysplasias 0.6304695517479797 1.3264865145208886 0.1846785990687287 1.0 0.9689628518592744 6 Q15738,Q15125 2 +Homologous recombination 0.6013895490947239 1.2826551502861157 0.1996129193048152 1.0 1.0 7 O60934,P49005,Q9Y2S7,P28340 4 +Embryonic stem cell pluripotency pathways 0.5368473155250371 1.2687018707768092 0.2045474149905459 1.0 1.0 14 P31749,O14641 2 +Development of ureteric collection system 0.6841628959276029 1.247127434631684 0.2123507749593443 1.0 1.0 4 O94813,P05556,Q13418 3 +Glucuronidation 0.608688763433413 1.2294761932430696 0.2188933183984331 1.0 1.0 6 O95394 1 +Genes controlling nephrogenesis 0.6052611551178707 1.2142088911876914 0.2246679661334223 1.0 1.0 6 O94813,P11047,P05556,Q13418 4 +Bdnftrkb signaling 0.5227774279044103 1.2112264276695408 0.225808636812052 1.0 1.0 10 Q15382 1 +Alanine and aspartate metabolism 0.6714318433006368 1.1948716844400813 0.2321371674217207 1.0 1.0 4 P11498 1 +Peroxiredoxin 2 induced ovarian failure 0.735545589463847 1.1931373761016344 0.2328155756763892 1.0 1.0 3 P42574 1 +Tp53 network 0.7332673720745122 1.184305097446562 0.2362923117375737 1.0 1.0 3 P42771 1 +Mapk cascade 0.5793378706642398 1.1807507754118116 0.2377017440871516 1.0 1.0 7 Q16539,P46734 2 +Thiamine metabolic pathways 0.7242968516916559 1.149559206772422 0.2503254679164386 1.0 1.0 3 P08559 1 +Primary focal segmental glomerulosclerosis fsgs 0.5122202935583807 1.1483554366004856 0.2508218623917235 1.0 1.0 19 P11047,P46013 2 +Synaptic signaling pathways associated with autism spectrum disorder 0.5139847186637383 1.1476362448269528 0.2511187606376501 1.0 1.0 13 Q15382 1 +Triacylglyceride synthesis 0.7231604342581613 1.1451615016792704 0.2521422627102856 1.0 1.0 3 O00116,Q9HCL2 2 +Leptininsulin signaling overlap 0.7149010226668154 1.11323125329361 0.2656091231835724 1.0 1.0 3 P31749 1 +Mirna regulation of p53 pathway in prostate cancer 0.6467757372097169 1.0939124898788564 0.2739933603786804 1.0 1.0 4 P42574 1 +Tca cycle in senescence 0.5707471286640265 1.0607988382229 0.2887813303166382 1.0 1.0 6 P08559 1 +Alpha 6 beta 4 signaling pathway 0.4949535226727336 1.0512496940069131 0.2931439250351118 1.0 1.0 12 P31749,P11047 2 +7q1123 copy number variation syndrome 0.3353679108318414 1.0480998384330265 0.2945926107389587 1.0 1.0 48 O00159,P36957,Q15056,P09622,P04406,Q02218,Q9NR30,P37198,P48047,Q9NY93,Q9BY44,O60264,Q8NFV4,P17096,O75122,O43709,P78347,Q5TC12 18 +Mitochondrial complex iv assembly 0.4949423820952359 1.0462847517909837 0.2954295833032843 1.0 1.0 13 Q9BSH4,O43819,P09669 3 +Nrp1triggered signaling pathways in pancreatic cancer 0.4860421485098952 1.0195094576972887 0.3079611654561307 1.0 1.0 10 Q9NWH9 1 +Somatroph axis gh and its relationship to dietary restriction and aging 0.6245159328911656 1.0032937914412925 0.3157191308106482 1.0 1.0 4 P31749 1 +Wnt signaling pathway 0.486912015127498 0.9982076134814076 0.3181786953586527 1.0 1.0 15 O14641 1 +Extracellular vesiclemediated signaling in recipient cells 0.5559224507024034 0.9952848137688438 0.3195977616307197 1.0 1.0 6 Q9NWH9 1 +Epithelial to mesenchymal transition in colorectal cancer 0.4737060376362849 0.9393948114889272 0.3475280759340609 1.0 1.0 20 Q16539,P31749,P46734 3 +Glycolysis and gluconeogenesis 0.4610828795294476 0.9384152162850686 0.3480310691883801 1.0 1.0 26 P10515,P00505,P09622,P04406,O95563,P11498,P08559 7 +Integrated cancer pathway 0.4750037406994646 0.933945085592247 0.3503322204654227 1.0 1.0 16 P42574,P31749,P54132 3 +Copper homeostasis 0.4653941707445247 0.9135135688524249 0.3609725005474313 1.0 1.0 10 P31749,O43819,P78536 3 +Pathways affected in adenoid cystic carcinoma 0.4667999079156485 0.9012819742151442 0.3674384154400179 1.0 1.0 20 P10412,P31749,P46100 3 +Ectoderm differentiation 0.4653412705388731 0.9001601275760437 0.3680350416617981 1.0 1.0 21 Q92930,O15439,P40123,P51608,Q9P2E9,P17480 6 +Pi3kaktmtor vitd3 signaling 0.5051041692433232 0.8422664018622777 0.3996388529765071 1.0 1.0 7 P31749 1 +Focal adhesion pi3kaktmtorsignaling pathway 0.3216037819175268 0.8288946731507989 0.4071640098851992 1.0 1.0 47 Q9NWH9,P11047,Q15382 3 +Lung fibrosis 0.5377287414680538 0.8264090880822612 0.4085720698147304 1.0 1.0 5 P51608,Q86TI2 2 +Vitamin d in inflammatory diseases 0.4829160051117303 0.8177240497683956 0.4135147746443162 1.0 1.0 8 O60244,P46734 2 +P38 mapk signaling pathway 0.4628516486812946 0.8066449343687923 0.4198710776669261 1.0 1.0 9 P05114,P60953 2 +Transcription cofactors ski and skil protein partners 0.5637579447491192 0.7613341860346905 0.4464574865215991 1.0 1.0 4 Q96ST3 1 +Netrinunc5b signaling pathway 0.4393422060970281 0.7504923966627055 0.4529582013848472 1.0 1.0 15 P42574,Q06124,Q16539,P61586,P31749,Q15257 6 +Neural crest cell migration in cancer 0.4344116607825966 0.7494095908738778 0.4536103720495428 1.0 1.0 11 P31749 1 +Insulin signaling 0.29726129889997 0.7350203680040047 0.4623270896884319 1.0 1.0 51 P62330,P10586,P31749,P41440,P46734,Q15382 6 +Gdnfret signaling axis 0.6145836305470059 0.734977703498088 0.4623530732525138 1.0 1.0 3 O94813 1 +Regulation of sister chromatid separation at the metaphaseanaphase transition 0.4281812782673097 0.7283521959688704 0.466398018340924 1.0 1.0 10 O60216,Q9Y6D9,Q14683,O43683 4 +Complement system 0.4294853063883615 0.7253649424930168 0.4682281742829675 1.0 1.0 11 P11047 1 +Hedgehog signaling pathway wp4249 0.5533241119024952 0.7210295010551893 0.4708913641411894 1.0 1.0 4 Q9Y496 1 +Target of rapamycin tor signaling 0.4314765407485794 0.7204637793948806 0.4712394930964603 1.0 1.0 13 P31749,Q15382 2 +Heart development 0.6082873841300093 0.7122298600329217 0.4763224492839355 1.0 1.0 3 Q06124 1 +Oxidative phosphorylation 0.3949936325864223 0.6950091039104855 0.487049596251345 1.0 1.0 33 P19404,P56134,O75438,O95139,Q86Y39,O95168,O75380,P28331,P03915,O75787 10 +Parkinsons disease pathway 0.4382489237330716 0.6915115148223117 0.4892441469962083 1.0 1.0 9 P42574,Q16539 2 +Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc 0.4244530527820196 0.6766562464277854 0.4986240831266628 1.0 1.0 15 P36957,P10515,P09622,P50213,Q02218,P11498,P08559,Q96I99,O75390 9 +Egfr tyrosine kinase inhibitor resistance 0.4246515394906845 0.67335797596157 0.5007195771379005 1.0 1.0 17 Q9NWH9 1 +Mitochondrial complex iii assembly 0.4133866216192242 0.657764253207304 0.5106896276536681 1.0 1.0 10 O14949,Q9BRT2,P08574,Q9UDW1,P14927 5 +Histone modifications 0.4760134026845473 0.6529897318919397 0.513762898218578 1.0 1.0 6 P62805 1 +Clear cell renal cell carcinoma pathways 0.3505703682294519 0.6466409945094508 0.5178643197544424 1.0 1.0 40 P31749,Q15382 2 +Glycerophospholipid biosynthetic pathway 0.459337122030126 0.6433807082364592 0.5199770982311442 1.0 1.0 7 P48651,O00116,Q9HCL2,O15228,O14735 5 +Mecp2 and associated rett syndrome 0.4150797228820081 0.6380882295594755 0.5234162481515601 1.0 1.0 22 Q03518,Q13148,O75475,P51608,P31749,Q96ST3,Q05086,P08069 8 +Nonsmall cell lung cancer 0.4170041465520012 0.6375918868082474 0.5237393783684123 1.0 1.0 16 P42574,P31749,P42771 3 +Breast cancer pathway 0.404477407147479 0.6183720013510974 0.5363301496596664 1.0 1.0 26 P09874,Q07812,O14641,P31749,O60934,P08069,P19784 7 +Melanoma 0.4115710366727744 0.6147460626028258 0.538722434735047 1.0 1.0 15 P31749,P42771 2 +Ddx1 as a regulatory component of the drosha microprocessor 0.4850194640828407 0.6119370468128412 0.5405794094760157 1.0 1.0 5 O60934,Q92878,P49959 3 +Pi3kakt signaling pathway 0.3025773947877187 0.5990721743584047 0.5491247562212047 1.0 1.0 46 Q9NWH9,P11047,Q15382 3 +Effect of progerin on genes involved in hutchinsongilford progeria syndrome 0.4004773828039947 0.5886671583131233 0.5560845729290089 1.0 1.0 11 Q92769,Q13330,Q14839,O94776,Q13185 5 +Hif1a and pparg regulation of glycolysis 0.5669733781201358 0.5678189805998168 0.5701578902146176 1.0 1.0 3 P04406 1 +Focal adhesion 0.3382799490957743 0.5648511178564808 0.5721750344833301 1.0 1.0 40 P11047,P17655,Q9NWH9,P31749,P60953 5 +Glycerolipids and glycerophospholipids 0.471567143528636 0.5599035415836782 0.5755452329482866 1.0 1.0 5 Q9HCL2 1 +Leukocyteintrinsic hippo pathway functions 0.4389649437792116 0.5593784347684875 0.5759034758744723 1.0 1.0 7 P51153 1 +G13 signaling pathway 0.396564509540239 0.5418668267631294 0.5879102509344776 1.0 1.0 16 P62140,Q13576,P60953 3 +Urea cycle and associated pathways 0.3928136005032307 0.5390645805858207 0.5898422941987997 1.0 1.0 13 Q9Y619,P00367,P00505,P04181,P32322,P40925,P30038 7 +15q133 copy number variation syndrome 0.5572119071230303 0.5351625850540302 0.592537435927946 1.0 1.0 3 P50454 1 +Thyroid hormones production and peripheral downstream signaling effects 0.3940220562001199 0.5268339277597287 0.5983089199976099 1.0 1.0 18 Q15382 1 +Onecarbon metabolism 0.390178048861016 0.5168266165423 0.6052771980434213 1.0 1.0 15 P34896 1 +Gaba receptor signaling 0.4268859457324142 0.5113316045106102 0.6091188782826775 1.0 1.0 7 O95782,P53680 2 +Integrinmediated cell adhesion 0.3873989009921354 0.5082173642367095 0.6113009146745512 1.0 1.0 23 P31749,P17655,P46734 3 +Lipid metabolism pathway 0.3804006802011995 0.4920689419180049 0.6226706072444503 1.0 1.0 12 P31749 1 +Proximal tubule transport 0.3757420339345863 0.4895014032677072 0.624486761306295 1.0 1.0 10 O15439,Q9Y5K8,P08195 3 +Endochondral ossification with skeletal dysplasias 0.3742155140422271 0.4830955124924025 0.6290279202230782 1.0 1.0 10 P31749,P50454,P08069,Q9Y496 4 +Endochondral ossification 0.3742155140422271 0.4830955124924025 0.6290279202230782 1.0 1.0 10 P31749,P50454,P08069,Q9Y496 4 +Tgfbeta signaling pathway 0.3511388785916661 0.468568768389374 0.6393779055701068 1.0 1.0 34 P31749,Q9NWH9,P60953,P46734 4 +Rala downstream regulated genes 0.4279172072349289 0.4646864659344262 0.6421560017990928 1.0 1.0 6 P60953 1 +Physiological and pathological hypertrophy of the heart 0.3957632758922519 0.4457085410002488 0.655807794203491 1.0 1.0 8 P46734 1 +Preimplantation embryo 0.393742478121999 0.4380280209154643 0.6613659710251272 1.0 1.0 8 Q9P0M6 1 +Angiotensin ii receptor type 1 pathway 0.5255830606036122 0.4341576299896536 0.6641739785951841 1.0 1.0 3 Q06124 1 +Neuroinflammation and glutamatergic signaling 0.3675894030284798 0.4242610735879056 0.6713754246213883 1.0 1.0 24 P62140,P10515,P09622,P34896,Q01970,P78330,P31749,Q9Y617,P08559,P62136,Q13555 11 +Mirna regulation of dna damage response 0.3637524924326791 0.4204500197203393 0.674156733962382 1.0 1.0 26 P42574,Q7LG56,O60934,P41440,P35251 5 +Dna damage response 0.3650273279883332 0.4190157394743176 0.6752046294803149 1.0 1.0 25 P42574,Q7LG56,O60934,P41440,P35251 5 +Nucleotide excision repair in xeroderma pigmentosum 0.3371943347968817 0.4177317935967586 0.6761432240505247 1.0 1.0 35 P62805,P05114,P41440 3 +Pdgf pathway 0.3686349234791229 0.4172510971709562 0.6764947540397246 1.0 1.0 18 P53365 1 +Serotonin htr1 group and fos pathway 0.37142433227104 0.4093277606257602 0.6822991456220273 1.0 1.0 9 P46734 1 +Serine metabolism 0.3978585747145732 0.4024238601315575 0.6873721130743649 1.0 1.0 7 P78330,Q9Y617,P34896 3 +Small cell lung cancer 0.3600068591989769 0.3964310063022745 0.6917870960737718 1.0 1.0 14 P11047 1 +Malignant pleural mesothelioma 0.2904056511338302 0.3956021895894845 0.6923985215557358 1.0 1.0 72 P11047,Q9NWH9,Q16539,O14641,P31749,Q8NE86,P05114,P08195,P46734,Q15382 10 +P53 transcriptional gene network 0.3618689181969313 0.3741021970167242 0.7083282842028913 1.0 1.0 9 Q7LG56,P30038 2 +Glioblastoma signaling pathways 0.3549491921624232 0.3623552388177246 0.7170865841258283 1.0 1.0 20 P31749,Q9NWH9 2 +Orexin receptor pathway 0.3530121340344501 0.3613326667377073 0.7178507764309339 1.0 1.0 16 P17096,P55145,Q00059 3 +Praderwilli and angelman syndrome 0.3856141459682769 0.3597210320687941 0.7190557621733344 1.0 1.0 7 P42771 1 +Neuroinflammation 0.4126835374488594 0.3518278819111425 0.7249673470411051 1.0 1.0 5 Q16539 1 +Lncrna in canonical wnt signaling and colorectal cancer 0.3473029808642648 0.3405349718264249 0.7334536910379905 1.0 1.0 16 O14641 1 +Onecarbon metabolism and related pathways 0.3417663474874627 0.3348851570383086 0.7377117192366918 1.0 1.0 13 P34896,O15382 2 +Tca cycle aka krebs or citric acid cycle 0.3436308904421312 0.3275530678911891 0.7432496121697769 1.0 1.0 16 P36957,P31040,P09622,P50213,Q02218,Q96I99,Q99798,Q9P2R7,O75390 9 +16p112 distal deletion syndrome 0.3605669327319674 0.3206948167640007 0.748441675619218 1.0 1.0 8 P20339,Q9H2V7 2 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.3464151718657187 0.3205916879297237 0.748519837465099 1.0 1.0 9 P20339 1 +Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.3339946911006944 0.3084060295711414 0.7577733945009677 1.0 1.0 13 P17096,O43819,P00505 3 +Gpr40 pathway 0.4797832458609643 0.3038381914274961 0.7612511688184993 1.0 1.0 3 Q01970 1 +Translation inhibitors in chronically activated pdgfra cells 0.3373914513152652 0.3011604238267151 0.7632921668574173 1.0 1.0 18 P31749,P46734 2 +Pkcgamma calcium signaling pathway in ataxia 0.6994271932469034 0.288085739118511 0.7732811086296136 1.0 1.0 2 Q01970 1 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.3269503717099453 0.2856065708603343 0.7751794701912635 1.0 1.0 13 P31749,Q16539 2 +Tumor suppressor activity of smarcb1 0.3246915761384134 0.2843123989020922 0.7761709850999661 1.0 1.0 12 Q12824,P42771 2 +Ras signaling 0.3065535014371115 0.282385714381132 0.7776477677289029 1.0 1.0 35 P62330,Q9NWH9,P31749,P20339,P60953 5 +Microtubule cytoskeleton regulation 0.3286059417444192 0.2715288006061263 0.7859843517513561 1.0 1.0 22 P31749,O75962,P60953 3 +Type ii interferon signaling ifng 0.3439867805078356 0.2690234574928185 0.7879116314160903 1.0 1.0 8 P62805 1 +Photodynamic therapyinduced hif1 survival signaling 0.3171889907684094 0.2676945527565318 0.7889344431100704 1.0 1.0 11 P08559,Q07820 2 +Rett syndrome causing genes 0.324100157338808 0.2639626752711134 0.7918086797900323 1.0 1.0 16 P42858 1 +Microglia pathogen phagocytosis pathway 0.4149505980186135 0.2612898134180895 0.7938690215080011 1.0 1.0 4 O15143 1 +Angiopoietinlike protein 8 regulatory pathway 0.3064833061836589 0.2587238623714183 0.7958483067725117 1.0 1.0 33 P31749,P41440,P46734,Q15382 4 +Il1 signaling pathway 0.3221510763921532 0.2553413197764363 0.7984594887908798 1.0 1.0 17 P31749,P46734 2 +Male infertility 0.3224169627359352 0.2540094954565622 0.7994882223259132 1.0 1.0 18 P34896,P41440,P04179,P17096,P62805 5 +Phosphoinositides metabolism 0.3247224681255534 0.2534031706083209 0.799956677808948 1.0 1.0 9 Q9NTJ5,P78356,Q01970 3 +Tcell activation sarscov2 0.3212864310372683 0.2492472085366114 0.8031695642783052 1.0 1.0 19 Q15382 1 +Adipogenesis 0.314948413517405 0.2448098175352263 0.806603691897787 1.0 1.0 14 P17096,P14174,Q92879 3 +Aerobic glycolysis 0.3067391961317702 0.2441136351602567 0.8071428126196245 1.0 1.0 10 P19367,P04406,P00338,P06744,P00558,P60174,P08237,P04075,P06733 9 +Mrna processing 0.3012226812128786 0.2272107218343863 0.8202598908918997 1.0 1.0 102 Q96I25,P24928,P55769,Q9UKA9,Q15233,Q86U42,Q8WXA9,P09012,Q13247,Q13242,Q15428,P08621,O94906,P52272,Q92879,Q9BWJ5,Q13523,P33240,Q8IX01,O43809,Q92620,P62318,P62314,P08579,Q13435,Q6P2Q9,Q96DI7,P62304,Q15427,O95400,Q8IWZ8,P61011,Q8IYB3 33 +Acute viral myocarditis 0.3070301566316594 0.2162951438360485 0.8287576941375299 1.0 1.0 16 P42574,P31749,Q07812 3 +Gpr143 in melanocytes and retinal pigment epithelium cells 0.6617425384383387 0.2145497808204166 0.8301183511405843 1.0 1.0 2 Q01970 1 +Vitamin d receptor pathway 0.2967756282000343 0.201631398213668 0.8402048971090441 1.0 1.0 13 Q5VV42,Q92604 2 +Notch signaling pathway 0.2990492301927237 0.1995682831989517 0.8418182350900176 1.0 1.0 15 P31749 1 +Endoderm differentiation 0.2924555791163367 0.1950117530989235 0.8453837466234113 1.0 1.0 30 Q9HCM4,P11047 2 +Hepatitis c and hepatocellular carcinoma 0.2880685681759605 0.1816661254486155 0.8558447515351004 1.0 1.0 13 P31749,Q16539 2 +Dna replication 0.2862998424830136 0.1800453271082902 0.8571169837092902 1.0 1.0 30 Q7L590,P41440 2 +Thyroid stimulating hormone tsh signaling pathway 0.2918958338183523 0.1743282814358133 0.8616074741600666 1.0 1.0 20 P31749,P46734 2 +Dna damage response only atm dependent 0.2826477368026684 0.1560510191138168 0.8759928063439313 1.0 1.0 23 P42771,Q07812,O14641,P04179,P61586,P31749,P60953 7 +Mesodermal commitment pathway 0.280026767999006 0.1512324284467169 0.8797923702769883 1.0 1.0 23 Q9HCM4,Q8N3C0,P63173,P42858 4 +Gastric cancer network 2 0.2771117230258392 0.1493187289953843 0.8813021373424694 1.0 1.0 17 P11388,Q03701,P0CG13,Q86UE4,Q8TDN6,Q6PL18 6 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.2754400292253369 0.148212453821634 0.8821751036392551 1.0 1.0 16 P31749 1 +Agerage pathway 0.2738056786078063 0.1402114287925018 0.8884929422366783 1.0 1.0 21 P31749,P60953,Q16539 3 +Amino acid metabolism 0.2003448685925831 0.1380166430236074 0.890227264195538 1.0 1.0 54 P36957,P22033,P00505,Q15031,Q02218,Q96RQ3,Q8TD30,P11498,P08559,P40939,Q99798,P25325 12 +Smc1smc3 role in dna damage cornelia de lange syndrome 0.274106987172612 0.1367183109159777 0.8912534554253102 1.0 1.0 9 O60934,Q14676 2 +Dna irdouble strand breaks and cellular response via atm 0.2653052997836527 0.1359639555238735 0.8918497756252712 1.0 1.0 29 P54132,P42574,P42771,Q07812,Q15554,O60934,Q14676 7 +Nucleotide excision repair 0.2697949579496908 0.1358266584906481 0.8919583159308426 1.0 1.0 25 P41440 1 +Vegfavegfr2 signaling pathway 0.1900192645238136 0.1288933307287526 0.8974420539563666 1.0 1.0 183 P17655,Q9Y6I3,Q9Y5S2,P62330,P35613,P61353,P53680,Q16539,P31749,O60568,P60953,Q7Z478,Q8WU90,P46734,Q9Y613 15 +Transsulfuration and onecarbon metabolism 0.264301620388261 0.1267787441747073 0.8991155196614342 1.0 1.0 19 P34896 1 +Mirnas involved in dna damage response 0.3899276236429502 0.1196485852694919 0.9047615306645024 1.0 1.0 3 Q00534,P16104 2 +Hippomerlin signaling dysregulation 0.2555993552113005 0.115138007865614 0.9083357342965496 1.0 1.0 23 P62140,P17612,P05556,Q9NWH9,O96013,Q16531,P62136,P35222,P31323,P08069 10 +Hippo signaling regulation pathways 0.2517233405313387 0.1104935475290487 0.9120179668637278 1.0 1.0 22 P17612,P29992,Q9NWH9,Q01970,P61586,P60953,P35222,P31323,P08069 9 +Joubert syndrome 0.2500181645011599 0.1087464842884036 0.913403571323984 1.0 1.0 20 P09874,P61006,O75695,Q15382 4 +Cori cycle 0.2366989117291509 0.1051086154002222 0.9162896230743076 1.0 1.0 11 P19367,P18669,P04406,P00338,P06744,P00558,P60174,P37837,Q01813,P04075 10 +Extracellular vesicles in the crosstalk of cardiac cells 0.3360482654600322 0.1022259610838262 0.9185773217309976 1.0 1.0 4 P00533,Q96HC4,P04792 3 +Aryl hydrocarbon receptor pathway wp2873 0.2824894328411734 0.1015988817516632 0.919075067090288 1.0 1.0 7 P40123,Q07812 2 +Metabolic reprogramming in colon cancer 0.2140893927129423 0.0996026271362999 0.9206598080468972 1.0 1.0 37 P36957,P00505,Q96C36,P04406,P50213,P34897,P78330,P32322,Q9Y617,P08559,Q96I99,Q99798 12 +Transsulfuration pathway 0.2654184064431458 0.0991324726889492 0.9210330895874576 1.0 1.0 8 Q9NZL9 1 +Vitamin b12 disorders 0.3719688613574934 0.0954806185202399 0.9239330841009092 1.0 1.0 3 P22033 1 +Dopamine metabolism 0.5694905034669796 0.0893751765572482 0.9287837507448946 1.0 1.0 2 P17612 1 +Vitamin d metabolism 0.3637590890801007 0.085806068954726 0.9316205819469768 1.0 1.0 3 P38435 1 +Glycolysis in senescence 0.2127530976125767 0.0856210675175555 0.931767650500944 1.0 1.0 10 P19367,P11413,P00338,P04406,P00558,P04637,P09972,P06733,P14618 9 +Hereditary leiomyomatosis and renal cell carcinoma pathway 0.1919588875453464 0.0739141268992635 0.9410787149580122 1.0 1.0 11 P54619,P00338,Q13618,P04637,O00763,P62753,P08559,Q13131,P11177,Q13085 10 +Splicing factor nova regulated synaptic proteins 0.1764385849910441 0.0707419515266926 0.9436031319645828 1.0 1.0 16 Q9BY67,O43491,P20020 3 +Mbdnf and probdnf regulation of gaba neurotransmission 0.2289253252867755 0.0449092794041302 0.9641796204137374 1.0 1.0 7 P61586,O95782 2 +Mitochondrial fatty acid synthesis pathway 0.490804944226696 0.0383746220110416 0.9693889947753732 1.0 1.0 2 Q53GQ0 1 +Hostpathogen interaction of human coronaviruses autophagy 0.2570135746606357 0.0315704533084352 0.9748146064835594 1.0 1.0 4 Q8NEB9,Q99570,Q9NT62 3 +Insulin signaling in adipocytes normal condition 0.2569360675512793 0.0229751631951535 0.9816700846179698 1.0 1.0 3 P62753,O60343 2 +Insulin signaling in adipocytes diabetic condition 0.2569360675512793 0.0229751631951535 0.9816700846179698 1.0 1.0 3 P62753,O60343 2 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..578e03856580da032c6c3183855a8ab6882fecf1 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Arylamine metabolism", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir5093p alteration of yap1ecm axis", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanomaterialinduced inflammasome activation", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Overview of proinflammatory and profibrotic mediators", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin signaling", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selective expression of chemokine receptors during tcell polarization", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD11", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APC", "APEX1", "APMAP", "APPL1", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP2", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC9", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG9A", "ATIC", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "B3GALT6", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLM", "BLVRA", "BLVRB", "BPTF", "BRAP", "BRCA1", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "C15orf39", "C1QBP", "C21orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP2", "CASP3", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CEP170", "CEP250", "CEP44", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHUK", "CIP2A", "CKB", "CLASP1", "CLASP2", "CLIC1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERI1", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAH", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GID4", "GID8", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF2I", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP3", "IKBKB", "IKBKG", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIF15", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRP1", "LRPPRC", "LRRC59", "LRWD1", "LSM2", "LSS", "LTA4H", "LUC7L", "LZTFL1", "MACF1", "MAD1L1", "MAGED1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MAVS", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "METTL3", "MFAP1", "MFN2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MKLN1", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTOR", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA15", "NAA16", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFATC2IP", "NFKB1", "NIPBL", "NKRF", "NME1", "NME2", "NME3", "NONO", "NOP2", "NPC1", "NPC2", "NSD1", "NSDHL", "NSF", "NT5C3A", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OSBPL3", "OTUD7B", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PAXIP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNT", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PIBF1", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIP4K2B", "PISD", "PKM", "PKN1", "PKN2", "PLCB3", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", 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pval_100 pval_250 pval_500 +nucleolus_gc 34 83 2.130925298792802 0.0330952968091016 36.907766990291265 79.67718446601941 -1.342069158093771 0.3573216441012204 12.290032185888387 4.137815641901007 1.460174227676572 0.3627524615681838 0.3867843928672034 0.0028349238604318 5.060739147602957e-06 4.2271791175684993e-11 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f2e04fdc7409b19d1cf15d4bb51b0b26600c66ff --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 100.47058823529412 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6e9d675faba70c765cd1a5c8d190b2295d06e888 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6fb8f11e0bc6640d0ca9cd4f9d71ae38db8225fc --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +nucleolus_gc 0.4963398176987131 2.130925298792802 0.0330952968091016 0.4356839060702918 0.5626200457547275 83 Q14137,Q9BSC4,O00541,P09874,Q9NY93,Q2NL82,Q7L590,Q8TCT8,Q13823,P46087,P46013,O43709,Q9NZM5,P42696,O76021,P26373,Q9NR30,Q9Y4C8,O95478,Q99848,P61353,P36578,Q9BYG3,O15213,P62861,Q9H0S4,Q9BZE4,P84098,P54132,P17096,Q9H8V3,Q9NW13,Q13895,Q9Y237 34 +nucleolus_fc_dfc 0.5065267586001655 1.133700416801705 0.2569202347538697 0.9935790040084578 1.0 21 Q8IXT5,P22087,Q9GZS1,O15160,P19388,P55769,Q15233,O95602,Q9H9Y6,P17480,O60832 11 +nuclear_punctae 0.3716574590578771 0.9605142299342614 0.3367964727098131 0.9990710420295776 1.0 79 Q13503,Q8IXT5,P09234,O60244,P24928,P55769,Q15554,Q15233,P09012,O15160,Q15428,Q9GZS1,Q9ULX6,P50995,P46013,Q13148,Q96FJ2,P08579,P17480,P19784,P54132,O95400,P67870 23 +chromatin 0.3763771089140387 0.7449202856304289 0.4563199110489715 0.9999683161258092 1.0 96 O15164,Q9NW64,Q96T37,Q8IXT5,Q12824,Q92769,P09234,Q96I25,Q15233,Q9UMS4,P09012,P11388,P19387,P28370,Q15428,Q9ULX6,P51608,Q8TAQ2,P46013,Q9BWJ5,Q13523,Q9BTD8,P07305,Q9Y5B9,O60216,P08579,Q13435,P05204,P11387,Q6P2Q9,Q96DI7,Q15427,O60264,Q8WYA6,P17096 35 +membrane 0.3446774879990358 0.6606487999298453 0.5088375656751931 0.9999943658626004 1.0 83 Q15286,Q13740,P46939,P41440,O00159,Q9Y6I3,Q9Y5S2,O15144,P60953,P51153,P08069,P61160,Q13492,P53680,P31749,O43795,P78356,Q02952,P04439,Q13308,Q92930,P62330 22 +er 0.3342429819826366 0.540690768064763 0.5887207427792345 0.9999997243704914 1.0 86 P04844,Q9Y5M8,Q9NTJ5,O75340,O75396,Q9NP72,O96005,Q9P0L0,P48651,P51153,Q9H6H4,Q16513,P84085,Q6NUK4,P60468,P46977,Q15125,Q92930,Q86Y07,Q07960,P39656,P61011,P61019,Q9P0I2,Q06136,Q15738,Q8WVM8 27 +nucleoplasm 0.1768202361153364 0.1855694215101444 0.8527824351115227 0.9999999999999928 1.0 386 Q96T37,Q13503,Q12824,P53365,Q7Z6M1,O60244,Q15554,Q7L590,P46734,Q15382,P31483,Q9Y5S2,Q9Y4P1,P60953,P46013,P07305,Q9HD47,Q16539,P31749,P14174,P54132,Q9UHY1,P57076,Q969T9,O95400,Q9Y237 26 +cell_contact 0.2676587511843248 0.1458848250510435 0.8840123112750269 1.0 1.0 31 Q13740 1 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..060db96915c0fe3b52ce9909bdba7871d9abcd0c --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1", "AKT1S1", "ALCAM", "ALDH9A1", "ANAPC16", "ANAPC2", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "APC", "APPL1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATG9A", "ATL2", "ATL3", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLM", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1", "BUB1B", "BUD23", "BYSL", "C1orf123", "C21orf59", "CAD", "CALD1", "CALM3", "CAMK1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CASP2", "CASP3", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDKN2A", "CDS2", "CEP170", "CEP250", "CETN2", "CHEK1", "CHEK2", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLINT1", "CLNS1A", "CLPTM1", "CLTA", "CLTC", "CNN2", "COIL", "COMMD1", "COMMD2", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTCF", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCP1A", "DCP1B", "DCP2", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBNA1BP2", "EBP", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC8", "EMG1", "ENO1", "EPN1", "EPS15", "ESD", "ESYT1", "EWSR1", "EZR", "FAM50A", "FANCA", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GNL2", "GNL3", "GOLGA2", "GOLT1B", "GORASP2", "GPR107", "GRB2", "GSK3A", "GSK3B", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HIP1", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPBP1", "HSPH1", "HUS1", 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"NOL10", "NOL11", "NOM1", "NONO", "NOP2", "NOP53", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "OXSR1", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAK1", "PAK2", "PAK4", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PFDN6", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHGDH", "PI4K2A", "PI4KB", "PICALM", "PIK3C2A", "PIK3C3", "PIN4", "PIP4K2B", "PKM", "PKN1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "PPM1G", "PRKAA1", "PRKACA", "PRKCD", "PRKDC", "PRMT9", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTGES3", "PTK7", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGRF", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "REEP3", "REEP4", "REEP5", "RER1", "RHEB", "RHOA", "RHOG", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "SACM1L", "SAE1", "SAR1A", "SAR1B", "SARS", "SBDS", "SCAMP2", "SCD", "SCFD1", "SCYL2", "SEC16A", "SEC22B", "SEC23A", "SEC24C", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC35F2", "SLC6A15", "SLC9A3R1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPC", "SNRPD2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX9", "SPNS1", "SPOUT1", "SPPL2A", "SPTLC1", "SPTLC2", "SQSTM1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK2", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STIP1", "STK26", "STK4", "STT3A", "STT3B", "STX12", "STX18", "STX6", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "TARDBP", "TCOF1", "TERF2", "TFRC", "TIA1", "TJP1", "TJP2", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM192", "TMEM87A", "TMPO", "TMPO", "TNPO1", 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"FAU", "FBL", "GNL2", "GTPBP4", "H1F0", "HDAC2", "HLA-A", "HMGA1", "HMGN2", "IGF1R", "KDSR", "MAP2K3", "MAPK14", "MCM10", "MECP2", "MED14", "MED21", "MIF", "MKI67", "MYO1B", "MYO1C", "NIFK", "NOL10", "NONO", "NOP2", "NOP53", "NRBP1", "NSA2", "NSDHL", "PARP1", "PDCD6", "PES1", "PICALM", "PIN4", "PIP4K2B", "PKN2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2C", "POLR2E", "PRPF19", "PRPF4B", "PRPF8", "PTDSS1", "PTK7", "RAB13", "RAB18", "RAB2A", "RAB35", "RAB8B", "RABEPK", "RAD21", "RANGRF", "RBM12B", "RBM15", "RBM17", "RBM19", "RBM22", "RBM28", "RBM34", "RBM42", "REEP3", "REEP4", "RHEB", "RPL13", "RPL19", "RPL27", "RPL4", "RPN2", "RSL1D1", "SACM1L", "SCFD1", "SEC22B", "SEC61B", "SF3A2", "SF3B2", "SF3B4", "SF3B5", "SLC19A1", "SMARCA1", "SMARCA5", "SMARCB1", "SMARCC2", "SNRNP40", "SNRPA", "SNRPB2", "SNRPC", "SNU13", "SPPL2A", "SRP54", "SRPRB", "STT3A", "SUPT16H", "TARDBP", "TERF2", "TIA1", "TOP1", "TOP2A", "TRIM24", "TSR1", "UBTF", "UTRN", "VAPA", "VRK2", "WBP2", "WDR46"]} \ No 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sha256:a17f5c18c8fbe7b9ff7d6eb1ee76374924f1aac6bef02bbd4a42a8d5b55b6f86 +size 77744 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2af8ab590a1cb89e1d6f4781f84d66afeb9a2fab --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +histone 7 9 2.689108542585352 0.0071643119750166 6.609223300970874 9.031553398058252 -1.6306599901637746 0.1679998135987644 2.1722460253840654 0.5227582880559347 1.3516587276133298 0.2649142488697017 1.0 0.1951188871774342 0.0001593029984848 5.495573063421239e-06 +exoribonuclease 5 12 2.061528187044339 0.0392526772080024 4.483009708737864 9.9126213592233 -0.6791960165383605 0.4683675943914054 2.353927243124808 2.0988059301324924 0.7994175624696258 0.3019615814287166 1.0 1.0 0.4065747127007614 0.0809536104076691 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c419375ab7804c004f3f154e4b7281bbb4d6a3d1 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 159, + "title": "Average number of proteins per term", + "value": 14.169811320754716 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..861301ede7a08f2f2ff79cbfee4dec985ebc9d7b --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a7a72d136c55ec58f85d276e7055dd0f8bddf73e --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,47 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +histone 0.8512001287478345 2.689108542585352 0.0071643119750166 0.6812109640858325 0.6781595951454438 9 P10412,O75367,P16403,Q9P0M6,Q92522,P62805,P07305 7 +damaged DNA-binding protein 0.8877114230163612 2.0690600616447608 0.0385404509090019 0.9980678905413308 0.6781595951454438 4 Q9NQE9 1 +exoribonuclease 0.6860503370195802 2.061528187044339 0.0392526772080024 0.998282644967355 0.6781595951454438 12 Q5RKV6,Q06265,Q96B26,Q9H9L3,Q9GZR2 5 +ribosomal protein 0.5479243123075459 1.912272309490676 0.0558412755951014 0.9998923146368656 0.6781595951454438 124 Q7Z7F7,Q14137,P83731,Q5T653,Q02878,P62424,P18077,Q9Y3U8,P82914,P62269,P55769,P50914,P62701,P62280,P62750,P62841,P62857,Q9Y3D3,Q9UHA3,P39019,Q9BYD6,P82912,P62277,P46776,P62081,O76021,P26373,P63173,P61353,P36578,P62910,P62847,P82675,Q8N983,Q9H2W6,P83881,P62899,Q9Y2R9,P84098,P39023,P32969,P60866,P62917,P49406,Q6DKI1,P82664,P47914,Q92665,P61313,Q9NX20,P62244 51 +phosphatase modulator 0.6479676942839503 1.4975812863881055 0.1342420717951467 0.9999999998888166 0.7477826142407638 7 Q96QC0,Q15435 2 +secondary carrier transporter 0.6004173564661268 1.4893773710708778 0.1363880239810198 0.9999999999250682 0.7477826142407638 9 Q02978,O95202,Q9UBX3,Q8TB61 4 +DNA-directed RNA polymerase 0.5487074300664994 1.3408236813481162 0.1799777055534908 0.99999999999998 0.8065402900516663 17 P62875,Q13503,O15446,O15160,Q9GZS1,P19388,P24928,O95602,P62487,Q9H9Y6 10 +zinc finger transcription factor 0.6288266743199894 1.3191724970137555 0.1871114507033038 0.999999999999995 0.8065402900516663 6 Q9UBW7 1 +RNA methyltransferase 0.5458321749755107 1.3174570273826984 0.1876854763013311 0.9999999999999956 0.8065402900516663 14 Q9NXH9,Q8IY81,Q969Y2 3 +transaminase 0.5397894892399193 1.3006961457717388 0.193362482079396 0.9999999999999986 0.8090693329111569 10 P00505,O15382,Q8TD30,Q06210,Q9Y617 5 +mutase 0.6078680412393922 1.2258203544644777 0.22026628574296 1.0 0.8769753696532241 6 Q96G03,O95394,P22033 3 +RNA splicing factor 0.3934882652545546 1.067505141578189 0.2857437931330167 1.0 0.914204019563435 85 Q9NW64,Q8IXT5,Q96I25,Q8WXA9,P09012,Q13247,Q13242,O95391,Q15428,P08621,Q12849,O94906,P52272,Q12972,Q9ULR0,Q9BWJ5,Q8IX01,Q9Y4C8,O43809,Q9P2K5,P62318,P62314,P08579,P62312,Q13435,Q9BZJ0,Q6P2Q9,P62304,Q15427,O95400,Q8IWZ8,Q9H9Y2,Q9Y312,Q15637,Q86UA1 35 +RNA metabolism protein 0.4126129567197712 1.021263861151844 0.307129443372057 1.0 0.914204019563435 99 Q8NEF9,Q96T37,O00541,Q9BVJ6,Q9HAU5,Q86V81,Q68CQ4,Q15233,Q9Y3Y2,Q9BY77,O00567,Q9Y3A5,A0AV96,Q9NQ55,Q9BQ75,Q9UN86,Q96KR1,O75616,Q9Y520,Q9Y6M1,Q8TDN6,Q5T8P6,Q9P2N5,Q9Y2P8,Q8IY67,O75127,P78406,Q96BK5,Q9Y3A2,Q969S3,Q99700,P61011,Q12906,O75683,Q9H583 35 +nucleotidyltransferase 0.5650070835897936 0.9419310956396596 0.3462279185815919 1.0 0.9261505780085784 5 Q8NFW8 1 +endoribonuclease 0.5906385774967342 0.867099202934735 0.3858876572967942 1.0 0.9601282382873412 4 Q8N5L8 1 +RNA helicase 0.4580686730986209 0.8539396186606399 0.3931384462345484 1.0 0.9601282382873412 13 Q8IX18,Q9H2U1,Q92620,Q7L2E3,Q7Z478,Q9H6R0 6 +peroxidase 0.579524903084475 0.8230700017296694 0.4104681867236599 1.0 0.9601282382873412 4 P30048,Q13162 2 +carbohydrate kinase 0.5024466115836848 0.7633490831445342 0.4452552370945934 1.0 0.9681031290327404 6 P51570,P00558,Q03426,P17858 4 +mitochondrial carrier protein 0.4915267053034119 0.7173033174438723 0.4731869607163015 1.0 0.9899569309722624 6 Q9BSK2 1 +RNA processing factor 0.3990472272941807 0.6502394038972618 0.5155375919614498 1.0 1.0 30 O75152,Q13868,Q9NX58,Q6P6C2,Q9H0A0,Q9H974,Q9NPF4 7 +aldolase 0.5776217365784663 0.6041374252349464 0.5457522793010265 1.0 1.0 3 P37837 1 +general transcription factor 0.394991445542917 0.594310981488963 0.5523041351083249 1.0 1.0 28 Q9ULK4,Q00403,O75175,O60244,P13984,Q12789,Q9Y5Q9,Q92576,P78347 9 +small GTPase 0.3872617240572318 0.5216202742931794 0.6019347442791974 1.0 1.0 12 Q15382 1 +translation release factor 0.4980392156862762 0.517430176312695 0.6048558990320922 1.0 1.0 4 P62495,Q96E11,Q9BRX2 3 +translation initiation factor 0.2976655911519245 0.5088226079129895 0.6108765710783026 1.0 1.0 45 Q9UJA5,Q15056,Q9UI10,Q01085,P42696,P31483 6 +oxidoreductase 0.306040239320078 0.4756267901070207 0.6343402859142946 1.0 1.0 43 P09622,O43676,Q16795,Q86Y39,Q9Y320,O95168,P38117,P04179,O75380,P22570,Q8N4Q0,Q49A26,P03915,P23368,O14949 15 +ATP-binding cassette (ABC) transporter 0.3886553648078319 0.3701296499014446 0.7112858910103808 1.0 1.0 7 O15439 1 +chaperonin 0.3351465699607205 0.3331903433315296 0.7389906069920276 1.0 1.0 10 Q99832,P48643,P40227,O75347,P78371,P61604,P49368,P50990,P17987 9 +non-motor microtubule binding protein 0.324053112628964 0.256654047234908 0.7974458484230353 1.0 1.0 21 O75122,Q3KQU3,Q8WWK9 3 +ligase 0.3155411243687718 0.250157011928474 0.8024659280043307 1.0 1.0 28 A1L0T0,P05165,Q96RQ3,Q4G176,P11498,Q9P2R7,Q9UII2 7 +methyltransferase 0.3200865307091171 0.2493045711133292 0.8031251956997041 1.0 1.0 17 P34896,O43709 2 +vesicle coat protein 0.3194973351519902 0.2469175158249029 0.8049720602970063 1.0 1.0 24 P53365 1 +oxidase 0.3052064701828942 0.2147606811698556 0.8299539094643009 1.0 1.0 15 O14548,O43819 2 +glycosyltransferase 0.3020747335261744 0.1979232204030412 0.8431051362918505 1.0 1.0 23 O60762,O43909,P04844,Q9Y673,P46977 5 +chromatin/chromatin-binding, or -regulatory protein 0.2399951555905586 0.1618890368437183 0.8713932362667101 1.0 1.0 42 O15164,Q13610,Q9UQR0,P05114,Q96ST3,Q6PL18,Q9H0U9,Q9NPF5,P05204 9 +actin and actin related protein 0.326940248672909 0.1601387941953582 0.8727717421468204 1.0 1.0 6 Q9GZN1 1 +major histocompatibility complex protein 0.4122088092563285 0.1555355386366669 0.8763991390490451 1.0 1.0 3 P10321 1 +aminoacyl-tRNA synthetase 0.2610245648012159 0.1420326244519494 0.8870542363210514 1.0 1.0 33 Q5T160,Q9BW92,Q15031,Q5ST30,Q5JTZ9,Q9Y285,Q9NP81,Q9UGM6 8 +SNARE protein 0.2608544949836818 0.1375885810845982 0.8905655806666011 1.0 1.0 11 Q9UNK0,Q9NV70,Q86Y82,P51809,O15400 5 +primary active transporter 0.2696394609168816 0.1336767118592569 0.8936582211042399 1.0 1.0 22 Q9NS69,Q9Y5J7,P20020,Q96NB2,Q6P4A7,Q9BUN8,P54709,Q8N4H5,P09132,P16615 10 +chaperone 0.2234902943813787 0.1320278786037431 0.894962240829104 1.0 1.0 74 Q96JJ7,Q96BP3,Q9BRT2,Q9BT73,Q5TC12,P30405,Q9H2H8,P45877 8 +translation elongation factor 0.2314917587113336 0.096587187163524 0.9230542320787852 1.0 1.0 13 O43324,Q8NE71,Q9UG63 3 +actin or actin-binding cytoskeletal protein 0.2224116787431803 0.0880874157980549 0.929807198236274 1.0 1.0 24 O75340,Q9UHB6,P35241,O15143,P40123,P28289 6 +non-motor actin binding protein 0.1449562196799082 0.078700525461397 0.9372708275204852 1.0 1.0 31 Q9Y281,P35080 2 +glucosidase 0.3520861091887262 0.0734781677807015 0.9414256166920392 1.0 1.0 3 Q13724 1 +kinase modulator 0.2722607908240295 0.0672032201232505 0.9464199216345932 1.0 1.0 6 P54619,P13861,P67870,Q99570,P31323 5 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..82edcf73232acf55ac59c27ca15a67e41f6f19a1 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOBEC3C", "APPL1", "APRT", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6", "ARL6IP5", "ARMC9", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BDH2", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACTIN", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CCAR1", "CCAR2", "CCDC88A", "CCDC94", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CENPB", "CEP170", "CEP250", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNP", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF8", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOB", "ELOC", "ELP1", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FAHD1", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GGT7", "GID8", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HERC4", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUS1", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LETM1", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLAL1", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED14", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFSD5", "MGAT1", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTSS1L", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCDN", "NCOA5", "NCOR1", "ND5", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NENF", "NFKB1", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KB", "PICALM", "PIGL", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM47", "RBPMS", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF14", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC35B2", "SLC38A2", "SLC4A1AP", "SLC6A15", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTLC1", 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sha256:6477886c33588d08452c830acddcb2d5a36ce0b6aca8487b4577caaacaf2654d +size 140689 diff --git a/pharos_dto/basic/plot_5.png b/pharos_dto/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..56ce819bb40c65eea37716dcfd093f00d2a630bf --- /dev/null +++ b/pharos_dto/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fa223892352086857b40204a6003aa6ac0ff7cd52dc045bf1bce4ac94fdc21d7 +size 141994 diff --git a/pharos_dto/basic/plot_6.png b/pharos_dto/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..ddc3629dc1bb949a84248f82a7b8aba7e938987f --- /dev/null +++ b/pharos_dto/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:930b8f058aecbe6ddb316b7fbe81c658b7a53ff9b8640b9137ad25cee61dc078 +size 143847 diff --git a/pharos_dto/basic/plot_7.png b/pharos_dto/basic/plot_7.png new file mode 100644 index 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sha256:c7b1d98f287ab67398e8b788b085576792528203840a010d30b38f35089a9dfb +size 134826 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3e5f9c6c5e7bd72494bb5c26fa0f01a081e5890c --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a0e69698053ae38324316c9f636deafe04ada0ebaebb76f6b586d92fb6be99ef +size 173170 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4b190db74ed691dafa4eddbd2bb8ab0ba6fc9411 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Histone 7 11 2.510363741591617 0.0120606857511107 7.216019417475728 10.975728155339803 -1.5979454556388497 0.182832993896989 2.277887728681405 0.5524817827541809 1.3263740895704466 0.2762788415361712 1.0 0.1951188871774342 0.0001593029984848 5.495573063421239e-06 +Ribosomal protein 46 106 2.253235974039775 0.024244274292231 44.13834951456311 104.5509708737864 -0.839027584662447 0.4092064110759666 15.168720536445749 4.970282954685487 1.664286665300548 0.3711973750179467 0.029947979425984 0.0023202162213214 3.286343604756558e-05 1.980146463434677e-15 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bd249c8e8a3b792528b558744216fc3d44e36aa6 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 2075, + "title": "Average number of proteins per term", + "value": 3.1527710843373495 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6bf5a2782291c10e9323e6b0930cc446056871b0 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..52e4d9806703d901f9a068f3455e723378c12e2d --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,54 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histone 0.7761801231064092 2.510363741591617 0.0120606857511107 0.9999999999883772 0.3868330261999723 11 P10412,O75367,P16403,Q9P0M6,Q92522,P62805,P07305 7 +Ribosomal protein 0.5518041475814869 2.253235974039775 0.024244274292231 1.0 0.3868330261999723 106 Q14137,P83731,Q5T653,O00541,Q02878,P62424,P18077,Q9Y3U8,P62269,P62750,P55769,P50914,P62701,P62280,P62841,P62857,Q9Y3D3,Q9UHA3,Q9BYD6,P82912,P62277,P46776,P62081,Q8TDN6,O76021,P26373,P63173,P61353,P62910,P62847,P82675,Q8N983,P83881,P62899,Q9Y2R9,P84098,P39023,P32969,P60866,P62917,P49406,Q6DKI1,P47914,P61313,Q9NX20,P62244 46 +CK1 group 0.8862247120377862 1.7756161573951807 0.0757962050408989 1.0 0.3978433142420655 3 Q86Y07 1 +Oxygenase 0.700204933161428 1.5277296977457824 0.1265796634529687 1.0 0.4544166118770072 5 Q8NBJ5 1 +Exoribonuclease 0.5974490359311249 1.474499970803572 0.1403470255607419 1.0 0.469339502638128 9 Q96B26,Q06265,Q13868 3 +Decarboxylase 0.7937273823884242 1.4191061154017148 0.155868081316397 1.0 0.4915292837865105 3 A1L0T0,P23368 2 +DNA binding protein 0.3783293689839134 1.377227344034494 0.1684419703140802 1.0 0.5102439246740388 60 P10412,O75367,Q12824,P16403,Q9P0M6,Q9UQR0,P17096,O95400,Q9NQE9,O60934,P05114,Q92522,P62805,P07305 14 +Damaged DNA-binding protein 0.6451091972357268 1.28861457362611 0.1975321143098325 1.0 0.5413518966008244 5 Q9NQE9 1 +Transaminase 0.6025631143102482 1.2021928912648845 0.2292888028906952 1.0 0.5739134692378679 6 Q8TD30 1 +RNA helicase 0.5197960252712452 1.1955741287806652 0.231862792382848 1.0 0.5748927946528896 10 Q9BQ75,Q7Z478 2 +mRNA splicing factor 0.3582062276329706 1.1121857110365998 0.2660583102864347 1.0 0.6086780527501124 63 Q15233,P09012,Q13247,O95391,Q15428,P08621,Q13595,O94906,P33240,Q8IX01,Q9Y4C8,O43809,P62318,P62314,Q8IY67,P08579,P62312,Q9BZJ0,Q6P2Q9,P62304,Q8IWZ8,Q15637 22 +DNA-directed RNA polymerase 0.4970212610746278 1.057299664315279 0.2903748464277149 1.0 0.6296006335815135 13 P62875,O15160,P19388,P24928,O95602,P62487,Q9H9Y6 7 +VRK family 0.9234247814289986 0.920687716949573 0.357213490887398 1.0 0.698603198483837 2 Q86Y07 1 +Nuclease 0.3818044263944693 0.8723550413604266 0.3830147190849109 1.0 0.7192357847069594 40 Q9NW64,Q9UHB6,Q13868,Q8N5L8,Q9BVJ6,Q9BY44,Q06265,Q9H7B2,Q9Y3A2,Q7Z6E9,Q9Y520,Q8NHU6,Q96B26,Q9Y6A4,Q9Y2L1,Q9Y3A5 16 +Methyltransferase 0.4583199440984674 0.8506316452506398 0.3949740048585468 1.0 0.731107100875544 14 Q86VU5,P34896,P22061,O43709 4 +Peroxidase 0.579524903084475 0.8230700017296694 0.4104681867236599 1.0 0.7425645051888354 4 P30048,Q13162 2 +Mitochondrial nucleotide transporter subfamily 0.4682719530623475 0.750982613984702 0.4526631191590269 1.0 0.7756201257266564 8 Q9BSK2,O43808 2 +P-type ATPases 0.5136168136354244 0.7265279722573713 0.4675151658583063 1.0 0.7906226317489695 5 P20020,P54709,P16615 3 +Ribonucleoprotein 0.4026880783888144 0.5699210662852039 0.5687312359806156 1.0 0.8479653615790419 16 Q9P2K5,P52272,Q9H9Y2,P09132,Q9H583,O00567 6 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.5650523935169479 0.5613426015857544 0.5745640049202125 1.0 0.8493677929100802 3 Q9UBX3 1 +mRNA processing factor 0.3216442851881688 0.5446832461188317 0.5859713895647998 1.0 0.8514640289544535 78 Q96I25,Q15233,P09012,Q13247,O95391,Q15428,P08621,Q13595,O94906,Q96KR1,P33240,Q8IX01,Q9Y4C8,O43809,P62318,P62314,Q8IY67,P08579,P62312,Q9BZJ0,Q6P2Q9,P62304,Q8IWZ8,Q12906,Q15637,Q8IYB3,Q86UA1 27 +Lipid kinase 0.4458155201244811 0.5324648661870833 0.5944040692309362 1.0 0.8571692799524956 6 Q8NEB9,P78356,Q9UBF8 3 +Transcription cofactor 0.3908686242078234 0.5198801489070705 0.60314711211389 1.0 0.8618247527535969 15 O60244 1 +CK2 family 0.771781730479348 0.4617738979068905 0.6442434710441609 1.0 0.8825161021620866 2 P19784 1 +Lyase 0.3643262616357128 0.3991385113412727 0.6897911471383884 1.0 0.9093167254105 20 A1L0T0,O96005,P22830,Q9UJ83,Q9Y2P8,Q99798,P23368 7 +Chaperonin 0.3351465699607205 0.333190343331529 0.738990606992028 1.0 0.9217376389717418 10 Q99832,P48643,P40227,O75347,P78371,P61604,P49368,P50990,P17987 9 +ATP-binding cassette transporter family 0.4053947582085186 0.3288402594073392 0.7422764311912196 1.0 0.9217376389717418 5 O15439 1 +Signaling 0.3420442862520094 0.3190999563959535 0.7496507167264923 1.0 0.9255645422667842 17 Q5JRA6,Q9UHD1,Q07820,Q07812,O14641 5 +TK group 0.4354388261890782 0.3171591682402465 0.7511228307125433 1.0 0.9255645422667842 4 Q13308 1 +Small GTPase 0.338145904130048 0.308027551145659 0.7580613681323463 1.0 0.9280102294245536 24 P60953,Q15382 2 +Ca2+-ATPases 0.6822429906542037 0.2529915269231915 0.8002747607994889 1.0 0.9371163254282954 2 P20020 1 +KRAB box transcription factor 0.4072398190045269 0.2417133898287638 0.8090022535877526 1.0 0.939850755144409 4 P49711,Q7Z3K3,Q9Y2X9 3 +C2H2 zinc finger transcription factor 0.4072398190045269 0.2417133898287638 0.8090022535877526 1.0 0.939850755144409 4 P49711,Q7Z3K3,Q9Y2X9 3 +Non-protein kinase 0.3150421613809916 0.2305123145403443 0.8176936954996785 1.0 0.9405290566307276 21 Q9UBF8,P78356,Q8NEB9,Q03426,Q9UIJ7 5 +Nucleotidyltransferase 0.292827416539106 0.2014672648927273 0.8403332234566492 1.0 0.9415224045323968 31 P19387,P62875,P49642,O15160,P19388,P24928,Q5RKV6,P40937,O95602,P49005,Q8NFW8,P62487,Q9H9Y6,Q9BQG0 14 +CDK family 0.3542546771273333 0.1894394662814952 0.8497483948140421 1.0 0.941899232599677 5 P11802,Q00534,P06493,Q00535 4 +PI3/PI4 kinase family 0.4246576529246866 0.1784623776178195 0.8583598651761226 1.0 0.941899232599677 3 Q9UBF8 1 +Nucleic acid binding 0.4041411489316296 0.1764253188344302 0.8599598150739787 1.0 0.941899232599677 353 Q5T653,Q86V81,P55769,Q68CQ4,Q9NQE9,P62857,Q9Y3Y2,Q9BYD6,Q15022,O95391,Q15428,P08621,O94906,P49750,P52272,P46776,P62081,Q8TDN6,Q92576,P07305,Q9HCN4,Q9Y4C8,P05114,P62847,P82675,Q8N983,P62312,P08579,P47914,Q9Y5Q8,Q9HCU5,Q9NX20,P62244,Q14137,O00541,P16403,O15226,P18077,Q9Y3U8,P50914,P62701,P62280,Q9Y3D3,P49790,P39019,Q8WXA9,P82912,P62805,P10412,Q13247,Q9UBU8,Q9UN86,Q5T8P6,Q13330,P61353,P62318,P62314,Q8IY67,P84098,Q9ULM3,O75152,Q6P2Q9,Q9P0M6,Q5JTZ9,O95400,Q8IWZ8,P61011,P61313,Q12906,O75683,O75367,Q12824,Q8IXT5,Q02878,P62424,Q9UQR0,Q15233,Q9UHA3,P09012,O00567,P08708,P30050,P33992,Q13601,Q13347,P62854,O60934,P62753,Q92522,O43809,P13984,P62910,P83881,P62899,Q9BZJ0,Q9UJA5,P49406,Q6DKI1,P17096,Q969S3,Q9H583,P83731,P16402,P62269,P62750,P62841,Q9BY77,Q15056,P62277,Q13595,Q96KR1,P33240,O76021,P26373,P63173,Q9P2N5,Q9Y2R9,P05204,P39023,P32969,P60866,P62917,P78406,Q99700,Q9H9Y2,Q15637 126 +Actin and actin related protein 0.326940248672909 0.1601387941953582 0.8727717421468204 1.0 0.941899232599677 6 Q9GZN1 1 +RNA binding protein 0.4136039785463675 0.1587737717474568 0.8738471137642274 1.0 0.941899232599677 271 Q5T653,Q86V81,P55769,Q68CQ4,P62857,Q9Y3Y2,Q9BYD6,O95391,Q15428,P08621,O94906,P52272,P46776,P62081,Q8TDN6,Q9Y4C8,P62847,P82675,Q8N983,P08579,P62312,P47914,Q9NX20,P62244,Q14137,O00541,P18077,Q9Y3U8,P50914,P62701,P62280,Q9Y3D3,P49790,P39019,Q8WXA9,P82912,Q13247,Q9UN86,Q5T8P6,P61353,P62318,P62314,Q8IY67,P84098,Q6P2Q9,Q5JTZ9,Q8IWZ8,P61011,P61313,Q12906,Q8IXT5,Q02878,P62424,Q15233,Q9UHA3,O00567,P09012,P08708,P30050,Q13601,Q13347,P62854,P62753,P62266,Q8IX01,O43809,Q9P2K5,P62910,P83881,P62899,Q9BZJ0,Q9UJA5,P49406,Q6DKI1,P62304,Q969S3,Q8NC51,Q9H583,Q8IYB3,Q86UA1,P83731,Q96I25,P62269,P62750,P62841,Q6P1L8,P20042,Q9BY77,Q15056,Q13242,P62277,Q05519,Q12849,Q13595,P51398,P46777,Q96KR1,P33240,O76021,P26373,P63173,Q9P2N5,Q9Y2R9,P39023,P32969,P60866,P62917,P78406,Q99700,Q9H9Y2,Q15637 111 +Polymerase 0.2762548656373413 0.1453574405214579 0.8844286652579756 1.0 0.941899232599677 24 P19387,P62875,P49642,O15160,P19388,P24928,O95602,P49005,P62487,Q9H9Y6,Q9BQG0 11 +Glycosyltransferase 0.2621570210234703 0.125752527533636 0.8999278208988135 1.0 0.9421545047250444 17 O60762,Q8N128,P04844,Q9BT22,P46977 5 +CMGC group 0.2464250292897217 0.1087885360309042 0.913370216770944 1.0 0.9455593212536388 15 Q13523,P19784,Q16539,P67870 4 +Chromatin/chromatin-binding protein 0.2427377709263004 0.1015005725512208 0.9191531030772606 1.0 0.946074449341638 21 Q9UQR0,Q9UBU8,O95400,P05114,P05204 5 +G-protein 0.2147239456508743 0.0943198223425831 0.9248551041555066 1.0 0.9477085573122794 34 P60953,Q15382 2 +Reductase 0.2300754415728939 0.0920920616822199 0.9266248955108662 1.0 0.9477085573122794 17 Q7LG56,O95168,Q9UBM7,Q9UDW1,P14927 5 +BUB family 0.5649683448899514 0.0851954942444868 0.9321059726314508 1.0 0.950427465950988 2 O43683 1 +SNARE protein 0.1931049157991984 0.0747312680366168 0.9404285289301292 1.0 0.9584426313998122 10 Q9UNK0,P51809,O15400,Q86Y82 4 +Vesicle coat protein 0.1641440476582608 0.0722922305937904 0.9423693476080914 1.0 0.959949139070589 21 Q13492,O95486,P53680 3 +Aminoacyl-tRNA synthetase 0.1527225845904655 0.0683956885262613 0.9454706538528406 1.0 0.9616919640905118 16 Q15031 1 +Bromodomain 0.209039545442851 0.0344836161129886 0.9724915070263274 1.0 0.9867578861025084 7 P25440,Q6PL18,P51532 3 +Carbohydrate kinase 0.4115164305094929 0.0202564511557462 0.9838387955949004 1.0 0.9972962876694764 2 P17858 1 +Other small molecule kinase 0.2085722909749501 0.0193565725081313 0.9845566540292194 1.0 0.9975366489798 6 O00764,Q16822,P00558,Q03426,P14618 5 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..389aa9f9242dd99382764484cb768a0ebe86ed29 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent DNA helicase Q4", "ATP-dependent DNA helicase Q5", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Actin-related protein 6", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyl cyclase-associated protein 2", "Afadin", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Ankyrin repeat and SOCS box protein 6", "Annexin", "Antibacterial response protein", "Antigen peptide transporter 1", "Ap2-associated protein kinase 1", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-1,4-galactosyltransferase 1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biogenesis of lysosome-related organelles complex 1 subunit 1", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 3", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-regulated heat-stable protein 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-2", "Caspase-3", "Cat eye syndrome critical region protein 2", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cathepsin B", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere-associated protein E", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 4a", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "Clathrin heavy chain 1", "Clathrin light chain A", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytokine receptor", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidylate deaminase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydroorotate dehydrogenase (quinone), mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EGFR family", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Epidermal growth factor receptor", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase/racemase", "Epiplakin", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-mannose 4,6 dehydratase", "GEK subfamily", "GHMP kinase family", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Geranylgeranyl transferase type-1 subunit beta", "Geranylgeranyl transferase type-2 subunit alpha", "Geranylgeranyl transferase type-2 subunit beta", "Girdin", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione hydrolase 7", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Homeobox protein CDX-2", "Homeodomain transcription factor", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "INSR family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 1", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 1 receptor", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon gamma receptor 1", "Interferon-induced, double-stranded rna-activated protein kinase", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin heavy chain isoform 5C", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF15", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Low density lipoprotein receptor adapter protein 1", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase inducer phosphatase 3", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MARK subfamily", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "MTSS1-like protein", "Magnesium transporter protein 1", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Mevalonate kinase", "Mevalonate kinase subfamily", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 5", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neural Wiskott-Aldrich syndrome protein", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Nf-kappa-b essential modulator", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor NF-kappa-B p105 subunit", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 3", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase catalytic subunit type 3", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Phosphoserine phosphatase", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 39", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SLU7", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein LSM14 homolog A", "Protein LSM14 homolog B", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein VAC14 homolog", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA polymerase II subunit A C-terminal domain phosphatase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-1", "RNA-binding protein with multiple splicing", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Rap guanine nucleotide exchange factor 6", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribonucleoside-diphosphate reductase subunit M2 B", "Ribose-phosphate pyrophosphokinase 1", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark1", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tbk1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein kinase wnk2", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 35 member F2", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "T-complex protein 11-like protein 1", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10A", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 17", "TBC1 domain family member 2B", "TBC1 domain family member 4", "TBC1 domain family member 8B", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TRIO family", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tetratricopeptide repeat protein 28", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin, mitochondrial", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor IIB", "Transcriptional activator protein Pur-alpha", "Transcriptional coactivator YAP1", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Triple functional domain protein", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone C", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tudor domain-containing protein 7", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type II cytokine receptor", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein phosphatase non-receptor type 9", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm6", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 26B", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle transport through interaction with t-SNAREs homolog 1B", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "WNK family", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 7", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "mRNA-decapping enzyme 1B", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "ANAPC1", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOBEC3C", "ARCN1", "ARFIP1", "ARFIP2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "B4GALT1", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CDX2", "CEBPZ", "CECR2", "CENPE", "CEP170", "CEP250", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF8", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELOB", "ELOC", "ELP1", "EMC2", "EMG1", "ENO1", "ENO2", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERC1", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GID8", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLRAP1", "LETM1", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK1", "MARK2", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME2", "MECP2", "MED14", "MED21", "METAP1", "METTL1", "MFAP1", "MFN1", "MFN2", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTSS1L", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCBP1", "NCL", "NCOA5", "NCOR1", "ND5", "NDC80", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEK9", "NFKB1", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGGT1B", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3C3", "PIK3R4", "PINX1", "PIP4K2B", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN9", "PTPRF", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RAPGEF6", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBPMS", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNF14", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC6A15", "SLK", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMN1*", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPHK2", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TAP1", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TJP2", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIO", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TTC28", "TTK", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP28", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS18", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VRK1", "VRK2", "VTI1B", "WARS", "WASHC5", "WASL", "WDHD1", "WDR1", "WDR4", "WDR82", "WIZ", "WNK1", "WNK2", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YAP1", "YARS", "YARS2", "YEATS2", "YEATS4", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "ABCC4", "ACO2", "ACTR6", "AK3", "ALG1", "ALYREF", "AP2S1", "ATAD2", "ATP1B3", "ATP2A2", "ATP2B1", "ATXN2", "BAX", "BOP1", "BRD2", "BRIX1", "BUB1", "BUD23", "CCT2", "CCT3", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC42", "CDK1", "CDK4", "CDK5", "CDK6", "CFAP20", "CHORDC1", "CHTOP", "CLPTM1", "CMAS", "CMSS1", "COLGALT1", "COMTD1", "CRNKL1", "CSNK2A2", "CSNK2B", "CSTF2", "CTCF", "DAP3", "DHCR7", "DHX29", "DIEXF", "DIS3", "DPM1", "DVL2", "EIF2A", "EIF2S2", "EIF3I", "EIF4H", "EXOSC2", "EXOSC6", "EXOSC8", "EXOSC9", "FAM177A1", "FECH", "G3BP2", "GPN1", "GPT2", "GRSF1", "GTF2F2", "GTF3C5", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HEATR1", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HMGA1", "HMGN1", "HMGN2", "HNRNPM", "HSPE1", "ILF3", "ILVBL", "KRR1", "LARS2", "LIMA1", "LSM6", "MAPK14", "MCL1", "MCM5", "ME2", "MED14", "MIA3", "MORF4L1", "MRPL1", "MRPL14", "MRPL16", "MRPL19", "MRPL2", "MRPL43", "MRPS11", "MRPS16", "MRPS5", "MRPS7", "MTA1", "MVK", "MYBBP1A", "MYEF2", "NBN", "NDUFB4", "NKRF", "NONO", "NOP56", "NUDT21", "NUP153", "PCK2", "PCMT1", "PDXK", "PES1", "PFKL", "PGK1", "PHF3", "PI4KB", "PICALM", "PIK3C3", "PIP4K2B", "PKM", "POGZ", "POLD2", "POLDIP3", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "PRDX3", "PRDX4", "PREB", "PRIM1", "PRPF39", "PRPF4B", "PRPF6", "PRPF8", "PRRC2C", "PTK7", "RAE1", "RAVER1", "RBBP6", "RBM12B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RCL1", "RFC5", "RHEB", "RPF1", "RPF2", "RPL12", "RPL13", "RPL14", "RPL15", "RPL19", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL29", "RPL3", "RPL31", "RPL32", "RPL35A", "RPL36", "RPL36A", "RPL38", "RPL5", "RPL6", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN2", "RPP25L", "RPS11", "RPS13", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS4X", "RPS6", "RPS7", "RRM2B", "RSL1D1", "RSL24D1", "SBDS", "SCML2", "SEC24A", "SERBP1", "SF1", "SF3A2", "SHMT1", "SLC25A10", "SLC25A17", "SLC25A33", "SLU7", "SMARCA4", "SMARCB1", "SNRNP70", "SNRPA", "SNRPB2", "SNRPD1", "SNRPD3", "SNRPE", "SNU13", "SREK1", "SRP19", "SRP54", "SRRM1", "SRSF11", "SRSF6", "SRSF9", "STT3A", "STX12", "STX7", "STX8", "SUGP1", "SUGP2", "SURF6", "SUZ12", "TBCA", "TCP1", "TDRD7", "TRA2A", "TRMT6", "UQCR10", "UQCRB", "UTP11", "UTP14A", "VAMP7", "VRK2", "YEATS2", "YLPM1", "ZC3H11A", "ZFR", "ZNF281", "ZNF622"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f992833098e822440037d9e5cdd1693394a72ac0 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:279354dcc85a30a0278eff23d5af19caf51e0b28a6e5ba0420e178702595cb1d +size 230517 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d9752f64bcde7c3d52fb03a0871b9304fad457d3 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b7b8418c39a4a985f369aa8646b1652399f9d7f8 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:33631ccdb6551a20558db7951e5f444b2c5521fd76646b454914c17fc463c6c2 +size 132445 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..dcb3685775ef61c5cd9c73e47cc2463543d7aeff --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2907e5203eeeaa2d0936ea6acbd1e921b7e801f3777d29638fb184fbb2ca6e16 +size 137646 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..6e1bae03b9c19e55959d45512235c81a643ee6f5 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e2faa14c6e029327bf19e248b0c9e6f7326fa769c7ed501f387b27e9964ec6bd +size 82624 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5a0dab312f82b6d546901571a91446a39c9db658 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Tbio 582 2550 3.4490771183196154 0.0005625060290612 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 0.1619673335826244 0.3395364082725592 0.0079858992602162 7.099240989370756e-06 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..611863accb8af9b4f0e11ad2268365944437b1ba --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 829.5 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4cafe548eb0d58ac5580d9e9e5e44c2697404820 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..34ff472ebed48be31d8f657c6dd2e68e1cb15edd --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.2010207946929909 3.4490771183196154 0.0005625060290612 0.0022481263498855 0.002250024116245 2550 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582 +Tdark 0.2775146954810326 0.1743602282827066 0.8615823687296278 0.9996329158341132 1.0 346 Q7Z7F7,Q5T653,Q7Z6M1,Q9HA65,P82914,Q96P47,Q9NQE9,Q8WVC6,Q8WVJ2,Q9NPL8,Q9BYD6,Q9BU23,Q9NVU7,Q8IUX1,Q8NHQ9,Q9BWJ5,O94919,P42696,Q1ED39,Q9NWH9,P82675,Q8N983,Q5HYI7,P62312,Q5TC12,Q8TBF4,Q9BSC4,Q6GMV3,Q9H501,P82912,Q7L8L6,Q96S52,Q9Y4W2,Q9BQ75,Q8TF01,Q9ULR0,Q9NUD5,Q96IX5,Q9BSH4,Q86VU5,Q5MNZ6,Q96GQ7,Q9Y2D4,Q3KQU3,Q9H2W6,Q9Y3C0,Q9GZN1,A0AV96,Q6ZXV5,Q8NFC6,Q8N201,Q96C57,Q9BPY3,Q9BTD8,Q9Y6V7,Q8N5L8,Q9UJA5,Q9Y6G5,Q96LJ7,Q6DKI1,Q9H9L3,Q5TFE4,Q5VTL8,P83731,Q96ER9,Q96KR1,Q99590,Q9BU76,Q9HCN8,Q8N4H5,Q12788,Q9HBM1,Q9P2N5,Q9Y5Q9,P82664,Q8TBP6,Q92665,Q9H9Y2,Q9P0I2 79 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..56a4357165c891e8a0fd81b8fc32af115a52c8f4 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf50", "C20orf27", "C21orf59", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC88A", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDR2L", "CDS2", "CDV3", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG4", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A1", "FAM114A2", "FAM118B", "FAM160A2", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1211", "KIAA2013", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAR2", "ABHD11", "ACAD9", "ACBD3", "ACO2", "ACSF3", "ACTR2", "ACTR6", "ADRM1", "AGAP3", "AGPS", "AHNAK", "AK3", "AKAP12", "AKAP8L", "AKAP9", "ALCAM", "ALDH4A1", "ALG1", "ALG5", "ALKBH5", "ALYREF", "ANKLE2", "ANXA11", "AP1B1", "AP2S1", "APPL1", "ARF5", "ARF6", "ARFIP2", "ARHGAP1", "ARL8B", "ARMC1", "ARMC10", "ARPC1B", "ARPC2", "ASCC1", "ASCC3", "ATG4B", "ATG9A", "ATP5J2", "ATP5O", "ATP6AP2", "ATP6V1C1", "ATP6V1D", "ATPAF1", "ATPIF1", "ATRX", "ATXN2", "BASP1", "BDH2", "BIRC6", "BOD1L1", "BOP1", "BRAT1", "BRIX1", "BSG", "BUD23", "BYSL", "C12orf43", "C1QBP", "C1orf35", 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a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..abafa247893a2249bf7904fcf454dc3378015cee --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosome biogenesis 0.5529993457258894 3.098357793583726 0.0019459633617233 0.2832899579887413 0.3327597348546962 63 Q14137,Q9NY93,Q2NL82,Q9UHA3,Q9Y3A5,Q9NYY8,Q07021,Q9NVU7,Q13823,Q13610,P46087,O75616,Q8TDN6,O43709,Q9NZM5,O60832,O95478,Q99848,Q9Y2P8,Q9BZE4,Q9H7B2,Q8IY81,Q9H9Y2,Q13895,Q9H9L3,Q9H583,Q9NUL7 27 +rRNA processing 0.4807770410612801 2.3378965453316862 0.0193926155306281 0.9648704769149692 0.7674290576411251 65 Q14137,P22087,Q9NY93,Q9NX58,Q9H0A0,Q9Y4W2,P46087,O43709,Q96B26,O60832,Q13868,Q9NR30,O95478,Q9H0S4,Q9UNQ2,Q99547,P62312,Q5RKV6,Q06265,Q9Y3A2,Q9H9Y2,Q8IY81,Q9H583 23 +Carbohydrate metabolism 0.6103959271206767 1.803586436752924 0.0712961639057931 0.9999967862806708 0.7674290576411251 24 P62140,P10515,Q14165,O95394,Q96C23,P31749,P08559,Q9H488 8 +Autophagy 0.5026876621282016 1.695371797374859 0.0900049125085851 0.9999999009904288 0.7674290576411251 38 O95140,P53365,Q9HA65,Q9BXS4,Q9Y4P1,P62820 6 +Growth regulation 0.5953658953524978 1.5885265425562165 0.1121673239830951 0.9999999985390936 0.812948160960482 11 Q8N2F6 1 +Glucose metabolism 0.6081286890896054 1.527990939477358 0.1265147875520837 0.9999999999099052 0.8653611468562531 9 P10515,Q15120,P31749,Q96G03,P08559,P11177 6 +Glycogen metabolism 0.6192997842734512 1.3654276502326703 0.1721186783102637 0.9999999999999906 1.0 7 P31749 1 +Respiratory chain 0.4739933249537358 1.3056612512513652 0.1916677807026703 1.0 1.0 35 P19404,P03915,O75438,O43676,O95139,Q86Y39,O95168,O75380,Q9P0J0,P28331,P08574,Q96CU9,Q16795,Q9UDW1,O14949 15 +Electron transport 0.3420585635361786 1.221962067397769 0.2217219719770349 1.0 1.0 49 O75438,O43676,P38117,Q9UDW1,P19404,P28331,Q96HE7,Q96CU9,P14927,Q86Y39,O75380,P08574,P03915,O75489,O95139,O43396,O95168,Q9P0J0,P22570,Q16795,O14949 21 +Potassium transport 0.6070115661918294 1.1229838858487944 0.2614443383052567 1.0 1.0 5 P54709 1 +Serine biosynthesis 0.6823943418246685 0.988315387552996 0.3229982116921581 1.0 1.0 3 P78330 1 +One-carbon metabolism 0.4770045032877658 0.9729030819820323 0.3306014730776783 1.0 1.0 10 P34896 1 +Glycogen biosynthesis 0.56785619619109 0.9541131964891304 0.3400263468968525 1.0 1.0 5 P31749 1 +Amino-acid transport 0.521995865850279 0.9181362233557536 0.3585475527640773 1.0 1.0 7 P08195,Q6P4A7 2 +Unfolded protein response 0.4836601136968247 0.906909638333741 0.3644545838294641 1.0 1.0 9 P55145,O95140 2 +Angiogenesis 0.4965837096596097 0.8809887928076381 0.3783238859262829 1.0 1.0 8 P35613 1 +Phospholipid biosynthesis 0.4329049565534993 0.742033481168898 0.4580670502738901 1.0 1.0 11 Q92604 1 +Proline biosynthesis 0.6112786489746728 0.7230160385844796 0.4696700306140382 1.0 1.0 3 P32322,Q96C36 2 +Transcription termination 0.6041895208365137 0.6975174057075584 0.4854790504524024 1.0 1.0 3 Q9UNY4 1 +tRNA processing 0.3977127802311844 0.6630454267361733 0.5073014607186048 1.0 1.0 31 Q9NXH9,Q9UJA5,Q969Y2,Q5VV42,P62312,Q9H974,Q9NPF4 7 +GPI-anchor biosynthesis 0.4567930020104576 0.5044319998903556 0.6139578358627649 1.0 1.0 5 Q96S52 1 +Adaptive immunity 0.3644881333888555 0.4139505047951736 0.6789103552853999 1.0 1.0 14 Q13740,Q07021,Q03518,P10321 4 +Heme biosynthesis 0.4059380372517261 0.3860929495533379 0.6994278312389528 1.0 1.0 6 P22830 1 +Phospholipid metabolism 0.3539886530033689 0.3858124529671256 0.6996355718948895 1.0 1.0 12 Q92604 1 +Notch signaling pathway 0.3937930956272109 0.3451950443203301 0.729947744117903 1.0 1.0 6 P78536 1 +mRNA transport 0.2509673156256392 0.2654178115083426 0.790687616464274 1.0 1.0 62 O00159,O75152,P37198,Q9UN86,Q9UKX7,Q8NFH5,P49790,Q9Y3Y2,Q9Y6M1,Q9BY77,Q8TEM1,Q8NI27,Q5SRE5,Q9BTX1,Q86W42 15 +Cell adhesion 0.3097549325592402 0.2516445035013072 0.8013158564530387 1.0 1.0 31 Q13740,P11047 2 +Glycolysis 0.313536424121946 0.2308939733435465 0.81739717282338 1.0 1.0 17 P18669,P09972,Q02218,P04406,P00558,P60174,P17858,P08237,P52789 9 +Calcium transport 0.3552191756039711 0.2294167441965738 0.8185450231956888 1.0 1.0 6 Q8NE86,O95202,P20020,Q9UM00 4 +Lipid biosynthesis 0.2224449531640367 0.2291646919697207 0.8187409140902044 1.0 1.0 49 Q92604,Q9H3P7,P11498,Q9HCL2,Q8NBQ5 5 +Hearing 0.6454627675610485 0.1867577422992571 0.8518505806559697 1.0 1.0 2 O60610 1 +Protein transport 0.2113004756721594 0.1531217754684601 0.8783022440311488 1.0 1.0 270 O60831,Q9HA65,Q9UMY4,Q9Y3C0,Q15286,Q99584,Q8N5M9,P20338,O75695,O00159,O75396,Q9NVU7,Q9NP72,Q99653,Q96JB2,Q9Y4P1,Q9UJY5,Q9BUN8,O14828,P51153,Q8N4H5,Q5VZ89,Q9BTX1,Q9NS69,O95235,O60826,Q03518,Q9HD47,P51148,Q9NV70,P53680,Q10567,P20339,Q9P2E9,Q5HYI7,P60468,Q92930,Q9NVJ2,P62330,Q9Y2D4,Q86Y82,O60220,Q8NFH5,P61019,P62820 45 +mRNA processing 0.3236850603829159 0.1376666866327198 0.8905038488751142 1.0 1.0 211 Q9NW64,Q5VTL8,Q96DF8,Q96I25,P55769,Q9UKA9,Q15233,Q9UMS4,Q9UNY4,Q86U42,Q8WXA9,O75643,P09012,O60306,Q86W42,Q13247,Q07021,Q7L8L6,Q8TCS8,Q13242,O95391,Q15428,P08621,Q9ULX6,O94906,Q12849,Q13595,P52272,Q99590,Q12972,Q92879,Q9BWJ5,P57678,Q9ULR0,P33240,Q8IX01,Q7L014,Q13148,Q96BP3,Q9UNP9,O43809,Q14684,Q92620,Q9H0S4,P62318,P62314,P08579,P62312,Q13435,Q9BZJ0,Q9H2H8,O00148,Q9Y3C6,Q9Y312,Q6P2Q9,Q96DI7,P62304,Q15427,Q8WYA6,Q8TBF4,O95400,Q9BUQ8,Q8IWZ8,Q9NW13,Q8NI27,Q15637,Q8IYB3,Q86UA1 68 +mRNA splicing 0.3299782601049408 0.1355197924445692 0.8922009165022429 1.0 1.0 186 Q9NW64,Q5VTL8,Q96DF8,Q96I25,P55769,Q9UKA9,Q15233,Q9UMS4,Q9UNY4,Q8WXA9,O75643,P09012,O60306,Q86W42,Q13247,Q07021,Q13242,O95391,Q15428,Q9ULX6,Q13595,O94906,P52272,Q99590,Q12972,Q92879,Q9BWJ5,P57678,Q9ULR0,Q8IX01,Q7L014,Q13148,Q96BP3,Q9UNP9,Q14684,Q92620,Q9H0S4,P62318,P62314,P08579,P62312,Q13435,Q9BZJ0,Q9H2H8,O00148,Q9Y3C6,Q9Y312,Q6P2Q9,Q96DI7,P62304,Q15427,Q8WYA6,Q8TBF4,O95400,Q9BUQ8,Q8IWZ8,Q9NW13,Q8NI27,Q15637,Q8IYB3,Q86UA1 61 +Amino-acid biosynthesis 0.251753360561126 0.121077185063459 0.903629899895246 1.0 1.0 12 P78330,P32322,Q9Y617,O15382 4 +Virus entry into host cell 0.5954175459752669 0.1167281465638377 0.9070754850095312 1.0 1.0 2 P49790 1 +Viral penetration into host nucleus 0.5954175459752669 0.1167281465638377 0.9070754850095312 1.0 1.0 2 P49790 1 +Apoptosis 0.2105406051599396 0.1125492688120297 0.91038790700568 1.0 1.0 123 P04406,P42574,P30405,Q6FI81,P31483,Q86W42,O75340,Q07021,O95140,Q07820,Q96A26,Q66K74,P42858,Q01085,Q14684,Q16513,Q9NWH9,Q07812,Q16539,Q9H0S4,P31749,O60216,Q9BY67,P19784,Q9NR09,O60333,Q8WYA6,Q8WWK9,Q9Y3E5,Q9P0J0 30 +Translocation 0.1883190801248986 0.1082797516908972 0.9137737839802964 1.0 1.0 46 Q9NS69,O00159,P37198,O60220,Q9P2E9,Q99595,P49790,Q8NFH5,Q5SRE5,P60468,Q9BTX1,Q8TEM1 12 +Protein biosynthesis 0.2034011117972871 0.1066879956524786 0.915036506329618 1.0 1.0 94 Q5T160,Q9NP81,Q15031,Q15056,Q9BY44,Q9UI10,O43324,Q7Z478,Q9UGM6 9 +Pentose shunt 0.5854687971058127 0.1055365298733112 0.9159500851782076 1.0 1.0 2 P37837 1 +Tyrosine catabolism 0.5640639131745457 0.0843799500387213 0.9327543479788478 1.0 1.0 2 P16930 1 +Phenylalanine catabolism 0.5640639131745457 0.0843799500387213 0.9327543479788478 1.0 1.0 2 P16930 1 +Molybdenum cofactor biosynthesis 0.5260777811275126 0.0559136658355494 0.9554105840992912 1.0 1.0 2 Q9Y697 1 +Chemotaxis 0.2907975559738869 0.0523756882427863 0.9582293454939634 1.0 1.0 4 O94813 1 +DNA condensation 0.2303743961352628 0.0458571909431221 0.963424074935904 1.0 1.0 7 Q86XI2,Q9NTJ3,Q6IBW4,Q15021,O95347,Q9BPX3 6 +Nucleotide biosynthesis 0.2080314009661806 0.0340713464511061 0.9728202574334206 1.0 1.0 7 P23919,O60256,P04818,P32321,P11908,Q14558 6 +Neurotransmitter transport 0.3789568887548983 0.0177639315120897 0.9858271787007132 1.0 1.0 2 Q12846 1 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8feba22229264a97dd638adbeab8f21224d252bc --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Activation of host autophagy by virus", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA repair", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAM17", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP8", "AKAP8L", "AKT1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALG13", "ALKBH1", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEX1", "API5", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP2", "ARHGAP35", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL8B", "ARMC10", "ARMC9", "ARMT1", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AUP1", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CASP2", "CASP3", "CBL", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCDC88A", "CCDC94", "CCNA2", "CCNB1", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPU", "CENPV", "CEP250", "CEP55", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CMPK1", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COG7", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DSC3", "DSG2", "DST", "DTL", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHBP1", "EHD1", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMG1", "EML4", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAM160A2", "FAM162A", "FAM208A", "FAM50A", "FAM83D", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXRED1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCC2", "GCFC2", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGT7", "GHITM", "GID8", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPHN", "GPI", "GPKOW", "GPR89B", "GPSM1", "GRB2", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HERC4", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD13", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDLR", "LDLRAP1", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRP1", "LRPPRC", "LRRC41", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGT1", "MANF", "MAP1S", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "METTL1", "METTL3", "MFAP1", "MFN2", "MFSD10", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MICALL1", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMGT1", "MMS19", "MOB4", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MRC2", "MRE11", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NACC1", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFKB1", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NMD3", "NME1", "NME2", "NME3", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUCKS1", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PAXIP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDZD8", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3C3", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "PPAT", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKCD", "PRKDC", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB4A", 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0000000000000000000000000000000000000000..0f1c3f6ffd14ed8cb38bc2c7b3eedf4279195787 --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac345af3dcb7aa7776af407fab44bf89a6ae8c26c7400bdbe8c30330ea418117 +size 75204 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..471551c8b2548b5dfb5d1eb599ba5b17c0d00527 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 116, + "title": "Average number of proteins per term", + "value": 22.732758620689655 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7f0f306c3b954272a44befb2204b407e88c6ef80 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a56222f0a6cb2ef32f05964d3cf48123a40c19dc --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,21 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Dystonia 0.7524042287784654 1.7517356302426568 0.0798192771998969 0.9999355410574778 0.9178908410008452 5 Q9ULV3 1 +Primary mitochondrial disease 0.455585868952266 1.4487621192923794 0.1474040259345161 0.9999999907483286 0.9178908410008452 98 O43676,O14949,Q969Y2,Q9Y3D3,Q9NPL8,Q8NI60,Q9UGM6,Q9NYY8,Q07021,P19404,Q9Y3D9,Q99797,Q8TCS8,Q8IUX1,P08559,P28331,Q96CU9,Q96IX5,Q9UMS0,P14927,Q5T440,Q9BQP7,P20674,Q9BW92,Q9BSH4,Q86Y39,Q9BRT2,O75380,Q9H845,Q9Y2R9,P08574,P03915,Q5ST30,Q96RP9,Q5JTZ9,O43819,Q6P4A7,Q7LG56,Q9P0J0,Q00059,Q9P2R7,Q16795,Q53H12 43 +Obesity 0.6676623633938901 1.3866932990909675 0.1655353047714913 0.9999999992355938 0.9178908410008452 5 Q9Y4W2 1 +Microphthalmia 0.5595959105663038 1.0897617152924997 0.2758181224745577 1.0 0.9587755731740064 7 Q5SRE5,P53701,A6NHR9 3 +Williams-Beuren syndrome 0.5394655591726185 1.0836574727617134 0.2785166980892177 1.0 0.9587755731740064 8 Q8NFV4,Q15056,O43709 3 +Diamond-Blackfan anemia 0.4950534833997747 1.0434195200370877 0.2967540368066581 1.0 0.9587755731740064 17 P08708,P18077,P61353,P62081,P62857,P62847,P39019,P61313,P62244 9 +Leukodystrophy 0.441273830231173 0.7577564438474453 0.4485968017829023 1.0 1.0 18 Q9UI10 1 +Dyskeratosis congenita 0.559320054959467 0.7441332745897439 0.4567958505987231 1.0 1.0 4 O60832 1 +Leigh syndrome 0.4118638972463708 0.6412342559033255 0.5213704963944481 1.0 1.0 11 Q9BSH4,P03915,P08559 3 +Parkinsonism 0.4049620377976967 0.6185671074910136 0.5362015762440109 1.0 1.0 10 Q96A57,O75787 2 +Ectodermal dysplasia 0.4239130434782584 0.499732446441948 0.6172634827132546 1.0 1.0 7 Q9Y6K9,O60716,Q9H4L7,Q14692,P61586,Q9H1A4 6 +Glutaricaciduria 0.4897983600547769 0.4889076459838593 0.6249070823148934 1.0 1.0 4 Q92947 1 +Spinocerebellar ataxia 0.3773908517225254 0.4873537792529629 0.6260076424500036 1.0 1.0 11 O15020 1 +Cataract 0.2914200975966584 0.1977669561521524 0.8432274006776943 1.0 1.0 31 Q8WVX9,Q9H6K4,Q3LXA3,Q8NHU6,Q9H078,Q5SRE5,Q03426,Q15125 8 +Palmoplantar keratoderma 0.2967877728412124 0.1515944874612842 0.879506781524799 1.0 1.0 8 P14923,P15924,Q06136 3 +Retinitis pigmentosa 0.2571176004641561 0.1180276642427654 0.906045738184552 1.0 1.0 18 O75695,Q96S66,Q13868,Q6P2Q9,Q92620,O94906,O75643 7 +Schizophrenia 0.5694905034669842 0.0893751765572527 0.9287837507448912 1.0 1.0 2 Q9NTZ6 1 +Congenital myasthenic syndrome 0.332026537997602 0.0559885756583403 0.9553509081899404 1.0 1.0 3 P53007,Q06210 2 +Holoprosencephaly 0.4835694905034517 0.0356602562814186 0.9715532612741248 1.0 1.0 2 A5YKK6 1 +Elliptocytosis 0.4510099487488518 0.0264437055047925 0.9789034343736548 1.0 1.0 2 P11171 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b2eac7299a516765f7753cd8a32e1b4c84a29c08 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atherosclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital erythrocytosis", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hyperlipidemia", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABCB1", "ABCB7", "ABHD11", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APPL1", "APRT", "ARCN1", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARMC9", "ARPC1B", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATRX", "ATXN10", "ATXN2", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRB", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C19orf70", "C1QBP", "C21orf59", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CANX", "CAP2", "CAPN1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC88A", "CCNA2", "CCNB1", "CCT5", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDX2", "CENPE", "CEP250", "CEP55", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHP1", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLIC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "CNOT3", "COA3", "COA7", "COASY", "COG2", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTDP1", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCAF8", "DCPS", "DCTN1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DIS3L2", "DKC1", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "ECT2", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC6B", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FABP5", "FAF1", "FAH", "FAM50A", "FAM83D", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLM", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI3", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPHN", "GPI", "GPT2", "GRB2", "GSDME", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GTPBP3", "GUSB", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HARS2", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HEXA", "HEXB", "HIBCH", "HIP1", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGXB4", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD13", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2R", "IKBKB", "IKBKG", "ILF3", "ILK", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INTS1", "INTS12", "IPO7", "IRF2BPL", "IRS4", "ITGB1", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIF11", "KIF14", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LGALS3BP", "LIPA", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRPPRC", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARK1", "MARS", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED23", "MFN2", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOGS", "MORC2", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFS", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MVK", "MYH10", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NACC1", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCOR1", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NFKB1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP56", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAK1", "PARK7", "PARN", "PARP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PCNT", "PDAP1", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIN1", "PINX1", "PIP4K2B", "PISD", "PKM", "PLAA", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PSPH", "PTDSS1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RABEP1", "RAC1", "RAD21", "RAD23A", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM15", "RBM28", "RBMX", "RDH11", "RDX", "RECQL4", "REPS1", "RFC1", "RFC2", "RHEB", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "RRM2B", "RTN2", "SACS", "SAMHD1", "SAR1B", "SARS", "SART1", "SASS6", "SBDS", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC38A2", "SLC3A2", "SLC9A3R1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRP54", "SRP72", "SRSF2", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE1", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBC1D8B", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TCEA1", "TCOF1", "TDRD7", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TK1", "TKFC", "TKT", "TMCO1", "TMEM126B", "TMEM165", "TMEM199", "TMEM230", "TMEM43", "TMEM63A", "TMF1", "TMLHE", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMU", "TSC2", "TSFM", "TSG101", "TSR2", "TTC19", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXN2", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBE2T", "UBE3A", "UBQLN2", "UBQLN4", "UBR1", "UBTF", "UFSP2", "UGCG", "UGDH", "UGP2", "UMPS", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP9X", "UTP4", "VAC14", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC5", "WBP2", "WDR1", "WDR26", "WDR36", "WDR4", "WDR45B", "WDR5", "WFS1", "WIPI2", "WNK1", "WRAP53", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "YAP1", "YARS", "YARS2", "YBX1", "YEATS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2"], "leading_proteins": ["AARS2", "ABHD11", "ACAD9", "AGK", "ANAPC1", "ATP6AP2", "BMS1", "BUD23", "C1QBP", "CIZ1", "CLCC1", "CLPB", "CNOT1", "COQ8A", "COX5A", "CTNND1", "CYC1", "DHX38", "DKC1", "DSP", "EBP", "EIF2B4", "EIF4H", "EPB41", "EXOSC2", "FAR1", "FASTKD2", "FOXRED1", "GCDH", "GFM1", "GFPT1", "GTPBP3", "HCCS", "IBA57", "IKBKG", "JUP", "KDSR", "LAS1L", "MGME1", "MIPEP", "MRPS16", "MRPS23", "MRPS7", "MVK", "ND5", "NDUFA11", "NDUFA13", "NDUFA9", "NDUFB3", "NDUFS1", "NDUFS6", "NDUFV2", "NFU1", "NUP188", "OPA3", "PDHA1", "PNPT1", "PRPF6", "PRPF8", "RBM12", "RHOA", "RP2", "RPL15", "RPL27", "RPL35A", "RPS15A", "RPS17", "RPS19", "RPS24", "RPS28", "RPS7", "RRM2B", "SCO2", "SFXN4", "SLC25A1", "SMARCAD1", "SMCHD1", "SNRNP200", "SPTBN2", 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sha256:3ee769cc8f62b9670385360cd63165638d95e59368cd40f2395a880d9f0fbcfc +size 149221 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7abcbd2f7ee159e53e79a51a18b2481437f587c9 --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e7266a8711405f5b3e8e2047569a22fab5511581da70b679a12b85e8c07097cd +size 75860 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fd6dfb394594cce01df6d332f881a20da0b45180 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 96, + "title": "Average number of proteins per term", + "value": 40.614583333333336 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..45a473d3c782f35946355911a31bb55bdaeb52a4 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..532cc4c3b747a3b2b72cd7a023eede73c0a648b0 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,30 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +rRNA-binding 0.6484566769275013 1.9215370655661563 0.054664034137339 0.9954681722450576 0.625835767633787 19 Q9NYY8,Q7L8L6,P62917,P62269,P62750,P62701,Q96EY7,O75616,Q9H9Y2,Q9NUL7 10 +Ribosomal protein 0.5322500388363496 1.7936847697971094 0.0728634975872537 0.9992988784960248 0.625835767633787 122 Q7Z7F7,Q8TAE8,P83731,Q5T653,Q02878,P62424,P61513,P18077,P82914,Q9Y3U8,P50914,P62269,P62701,P62280,P62750,P62841,P62857,Q9Y3D3,P39019,Q9BYD6,P82912,P08708,Q9Y3D9,P30050,P62277,Q96EY7,P62854,P46776,P62081,P62753,P26373,P63173,P61247,P61353,P36578,P62910,P62847,P82675,Q8N983,Q9H2W6,P83881,P62899,Q9Y2R9,P84098,P39023,P32969,P60866,P62917,P49406,Q6DKI1,P82664,P47914,Q92665,P61313,Q9NX20,Q8N5N7,P62244 57 +Protein phosphatase inhibitor 0.8795853786417973 1.750260041404261 0.0800734525861619 0.9996686380852324 0.625835767633787 3 Q96QC0 1 +Aminotransferase 0.6622205639262495 1.5630174559865249 0.1180484890530064 0.9999942098205328 0.6383835514832406 7 Q06210,Q8TD30,P00505,O15382 4 +Heparin-binding 0.6822349095399007 1.5560470027495372 0.1196969159031076 0.9999951616927386 0.6383835514832406 6 P10586 1 +Myosin 0.5845807977078306 1.4099324140729446 0.1585596404280242 0.99999993657791 0.7610862740545166 9 O00159,Q92614 2 +Topoisomerase 0.7385404101326891 1.2047520137975858 0.2282990497930035 0.9999999999843286 0.9529003817447104 3 Q02880,P11388 2 +Peroxidase 0.5186766086750392 0.7472737583612047 0.4548983293033513 1.0 1.0 5 P30048,Q13162 2 +Tyrosine-protein kinase 0.4411307267046861 0.6309855527720036 0.5280499708514677 1.0 1.0 8 P46734 1 +Dioxygenase 0.4050028313962193 0.583068237691327 0.5598473645819222 1.0 1.0 21 O00625,O60568 2 +Ribonucleoprotein 0.4735302824829441 0.5329963112064218 0.5940361338060343 1.0 1.0 184 Q7Z7F7,Q8TAE8,P83731,Q5T653,P09234,P22087,Q02878,P62424,P61513,P18077,P82914,Q9Y3U8,P55769,P50914,P62701,P62280,P62269,P62750,P62857,Q9Y3D3,P62841,P39019,Q9BYD6,P82912,O00567,P09012,P08708,Q9Y3D9,P30050,P62277,P08621,Q13601,Q96EY7,P52272,P46776,P62081,P62854,P62753,Q9BUJ2,O60832,P26373,P63173,P61247,O95478,P61353,P36578,P62318,P62910,P62847,P82675,Q8N983,P62314,Q9H2W6,P08579,P62312,P83881,P62899,Q9H583,Q9Y2R9,P84098,P39023,P32969,P60866,P62917,Q6P2Q9,P49406,Q6DKI1,P47914,P82664,Q92665,P61011,P61313,Q9NX20,Q8N5N7,P62244 75 +Helicase 0.3295000061268701 0.5179070864122299 0.6045230975251465 1.0 1.0 85 Q9H2U1,Q9NY93,Q8N3C0,Q9UNY4,Q9NVP1,O75643,O60306,Q8IYB8,P28370,P33992,Q8NHQ9,Q8TDD1,Q7L2E3,Q6ZRS2,Q7Z478,Q9H6R0,Q9BQ39,Q7L014,Q9Y6V7,Q9NR30,Q14839,Q2NKX8,P13984,Q13206,Q92620,Q9H0S4,P46100,O00148,P54132,O60264,Q86XP3,Q9BUQ8,Q14527,Q8IX18,Q9NUL7 35 +Rotamase 0.3822232696188266 0.4842449912247266 0.6282120102748829 1.0 1.0 23 P26885,Q96BP3,P30405,Q9Y237,Q9H2H8,P45877 6 +Glycosyltransferase 0.3486229677570067 0.4769490029728958 0.6333984363756859 1.0 1.0 35 O60762,Q8NBJ5,O43909,Q9Y673,Q04446,Q9BT22,O60568,Q9H488,P46977,Q7Z4H8 10 +Isomerase 0.2661906196701242 0.3772334187379815 0.7060001471486737 1.0 1.0 59 Q96JJ7,P26885,Q96BP3,O95394,Q96C23,P42126,Q9Y237,P30405,P14174,Q9H2H8,P45877,Q15125 12 +Ion channel 0.3312627437114522 0.3199382886071413 0.7490151120186503 1.0 1.0 10 Q8NE86,Q9BVC6 2 +Antioxidant 0.3601477235624214 0.2429050051722525 0.8080789881125987 1.0 1.0 6 Q13162 1 +Translocase 0.3077090550691738 0.2121438873989671 0.8319947816388111 1.0 1.0 23 O15439,Q03518,P03915,P28331 4 +Initiation factor 0.2823012351985252 0.2116914387423246 0.8323477676338258 1.0 1.0 36 Q9UI10 1 +Ligase 0.2490394345996223 0.1924789952062038 0.8473670196830141 1.0 1.0 73 Q5T160,Q6UB35,Q9BW92,P05165,Q15031,Q5ST30,Q96I99,Q4G176,Q96RQ3,Q9P2R7,P11498,Q9NP81,Q9UGM6 13 +RNA-binding 0.3003549580891534 0.1824846294454021 0.8552024157615732 1.0 1.0 375 Q96T37,P22087,P55769,Q8NHU6,Q9Y3Y2,Q86W42,Q9NYY8,P08621,Q9Y5A9,P46087,Q8NHQ9,P52272,Q96B26,Q92879,Q9BWJ5,Q9BQ39,P42696,Q13868,Q9NR30,Q9Y4C8,Q9UNP9,Q9NWH9,Q99547,P62312,P08579,O43347,Q99575,Q15427,Q96DE0,Q8TBF4,Q96QC0,Q9NW13,Q9NW64,Q9BRJ7,P18077,P62701,P62280,P31483,Q13247,Q7L8L6,Q9UN86,Q8TDD1,Q12972,Q9Y6M1,Q5T8P6,Q9NUD5,P52758,Q13206,P62318,Q8IY67,Q9Y2L1,Q6P2Q9,Q5JTZ9,P61011,P62487,Q12906,O75683,Q9NUL7,Q8IXT5,Q9H2U1,Q9ULW3,Q9HAU5,Q9NY93,Q9UKA9,Q15233,Q8TEA1,Q86U42,P09012,O60306,A0AV96,Q8TCS8,P30050,Q13601,P82979,O75616,Q01085,Q9BTD8,Q15424,Q7L014,Q9NXH9,Q9BUR4,Q9Y6V7,Q9BV44,Q13148,O43809,O95793,O00148,P62304,Q5RKV6,P78346,Q8NI27,Q8NC51,Q8IYB3,P09234,Q96I25,P62269,P62750,Q9BY77,Q9NVP1,O75821,P06748,Q15056,Q13242,Q12849,Q05519,Q13595,P46777,Q96EY7,Q96KR1,Q8IWZ3,Q9BUJ2,Q7L2E3,Q15061,P33240,O60832,Q9H6S0,Q9UKM9,Q14151,Q9Y224,Q9Y2R5,Q9BYG3,Q9H0S4,Q9P2N5,Q9UNQ2,Q00839,P18124,P62917,Q86XP3,Q9H9Y2,Q15637,Q06265 131 +Aminoacyl-tRNA synthetase 0.2671655205009519 0.148841770051382 0.8816784899890162 1.0 1.0 32 Q5T160,Q9BW92,Q15031,Q5ST30,Q5JTZ9,Q9Y285,Q9NP81,Q9UGM6 8 +DNA-binding 0.21303601079721 0.1411364275440797 0.8877621666459123 1.0 1.0 227 O15164,O75367,Q12824,O15226,P16403,Q9H2U1,P09874,Q9ULW3,P16402,Q12789,Q15554,Q15233,P49790,Q9NX58,Q9UNY4,Q5SSJ5,Q7L590,P62805,A6NHR9,P10412,P11388,Q00403,P33992,P51608,Q66K74,Q96KR1,Q12972,P46013,Q92522,Q9NUD5,P07305,Q14151,Q12905,Q13330,Q13148,Q14839,Q2NKX8,P13984,P82094,P05114,P16989,Q9Y5Q9,Q92541,P17480,P05204,P78347,Q8TAF3,P35251,P46100,P54132,Q6NSI4,Q9P0M6,P0CG13,Q96KM6,Q02880,O75475,P17096,Q9Y5Q8,Q96QC0,Q14527,Q9HCU5,Q00059,Q12906,Q49A26,O75683,Q9Y237 66 +Activator 0.1884158909388625 0.1090610502742114 0.9131540679360636 1.0 1.0 111 Q13503,Q12824,O60244,Q96L73,Q6PL18,Q9ULK4,Q5VUA4,Q9BUJ2,Q92879,Q9NPF5,Q12905,Q9BSH4,Q14684,O60216,Q9HAF1,P17480,P35251,Q9BZK7,Q00059,Q14527 20 +Acyltransferase 0.2330264665320289 0.1080712995117607 0.9139391344585291 1.0 1.0 34 P36957,P10515,Q00403,Q92604,P55084,Q9HCL2,Q9H0A0,Q9GZZ1,Q9NPF4 9 +Chromatin regulator 0.1579942081410062 0.1013372657607476 0.9192827346446246 1.0 1.0 83 O75367,P46100,Q12824,Q9P0M6,Q96L73,Q9BZK7,O43709,Q9HAF1,Q9NPF5 9 +Motor protein 0.2194743216925667 0.099086608595636 0.921069504552836 1.0 1.0 35 O95235,O00159,Q92614,O60333,Q9Y496 5 +Signal transduction inhibitor 0.2864897466827603 0.031019446174151 0.9752540313300384 1.0 1.0 3 P49841,Q9NWT1 2 +Thiol protease inhibitor 0.2846803377563461 0.0303749058527174 0.9757680578475044 1.0 1.0 3 P04080,Q9NR09 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9f64c218784ee60e430e9846602d17fdc1c1cc51 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKT1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ANKHD1", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APOBEC3C", "APRT", "AQR", "ARFGAP1", "ARFGAP3", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATRX", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BSG", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "CACTIN", "CAD", "CADM1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPU", "CEP55", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CUL5", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGFR", "EGLN1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERP44", "ESD", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "F11R", "FAH", "FAHD1", "FAM208A", "FAM213A", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPSM1", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD13", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "L2HGDH", "LACTB", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LEMD3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRPPRC", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFN1", "MFN2", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MTA1", "MTA2", "MTAP", "MTERF3", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MUT", "MVK", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCL", "NCOA5", "NCOR1", "ND5", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFKB1", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM7", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KB", "PIGG", "PIGK", "PIGL", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKCD", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REXO2", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIOX2", "RIPK1", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SARNP", "SARS", "SARS2", "SART3", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPEN", "SPHK2", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE1", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TCEA1", "TCERG1", "TCP1", "TDRD7", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TMCO1", "TMEM109", "TMEM126B", "TMEM63A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBP1", "UBR1", "UBR4", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTRN", "UXT", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VRK1", "VRK2", "WARS", "WARS2", "WASL", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR48", "WDR5", "WNK1", "WNK2", "WRAP53", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "ZADH2", "ZC3H14", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZMPSTE24", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF638", "ZRANB2"], "leading_proteins": ["AARS2", "ABCC4", "ABT1", "ACSF3", "ALG1", "ALG5", "ANKHD1", "AQR", "ASCC3", "ATAD2", "ATRX", "BCAT2", "BIRC6", "BLM", "BUD23", "CELF1", "CHD4", "CHTF8", "CHTOP", "COLGALT1", "CSTB", "CSTF2", "CXorf57", "DDX10", "DDX18", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX42", "DDX46", "DDX47", "DDX49", "DDX50", "DDX54", "DDX55", "DDX56", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DIMT1", "DIS3", "DKC1", "DLAT", "DLST", "DMAP1", "DPM1", "EBP", "ECI1", "EIF2B4", "EIF3G", "EIF4H", "ERAL1", "ERCC6L", "EXOSC2", "EXOSC6", "EXOSC8", "EXOSC9", "EXTL3", "FARSA", "FASTKD2", "FASTKD5", "FBL", "FKBP2", "G3BP2", "GADD45GIP1", "GALM", "GBE1", "GFPT1", "GLYR1", "GOT2", "GPAM", "GPT2", "GRSF1", "GSK3B", "GTF2B", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HADHB", "HEATR1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLTF", "HMGA1", "HMGN1", "HMGN2", "HNRNPM", "HNRNPU", "HNRNPUL1", "HP1BP3", "IGF2BP2", "ILF2", "ILF3", "KDELC2", "KIF1B", "KIF20A", "KIF3A", "KRR1", "LARS2", "LPGAT1", "LSM6", "LYAR", "MAP1S", "MAP2K3", "MCCC1", "MCM10", "MCM5", "MCU", "MEAF6", "MECP2", "MED14", "MED21", "MED23", "MIF", "MKI67", "MPHOSPH6", "MRPL1", "MRPL16", "MRPL19", "MRPL2", "MRPL43", "MRPL46", "MRPL50", "MRPL55", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS23", "MRPS31", "MRPS5", "MRPS7", "MSI1", "MTA1", "MTHFD1L", "MYO18A", "MYO1C", "NAA50", "NAT10", "ND5", "NDUFS1", "NIFK", "NKRF", "NONO", "NOP2", "NOP56", "NPM1", "NSA2", "NSD1", "NSUN6", "NUDT16", "NUDT16L1", "NUDT21", "NUP153", "OSGEP", "PABPN1", "PAK1IP1", "PARP1", "PC", "PCCA", "PGM3", "PIN4", "PIR", "PLOD3", "PNPT1", "POFUT1", "POLDIP3", "POLR2G", "POP1", "PPIC", "PPIE", "PPIF", "PPIL3", "PPP1R10", "PPP1R8", "PPWD1", "PRDX3", "PRDX4", "PREB", "PRPF8", "PSIP1", "PTBP2", "PTCD3", "PTPRF", "RAD21", "RALY", "RARS2", "RAVER1", "RBM12B", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM28", "RBM34", "RBM42", "RBM47", "RFC1", "RIDA", "RPF1", "RPL12", "RPL13", "RPL14", "RPL15", "RPL19", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL29", "RPL3", "RPL31", "RPL32", "RPL35A", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPP30", "RPS11", "RPS13", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS20", "RPS24", "RPS26", "RPS28", "RPS3A", "RPS4X", "RPS6", "RPS7", "RRP1B", "RTF1", "RTRAF", "SAFB", "SAFB2", "SARNP", "SARS2", "SERBP1", "SF1", "SF3B4", "SF3B5", "SLTM", "SMARCA1", "SMARCA5", "SMARCB1", "SMCHD1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD3", "SNRPE", "SNU13", "SRCAP", "SRP54", "SRRM1", "SRSF11", "SRSF6", "SRSF9", "STAU1", "STT3A", "SUCLA2", "SUCLG2", "SUPV3L1", "SURF6", "TACO1", "TAP1", "TARDBP", "TARS2", "TBL1XR1", "TDRD7", "TERF2", "TFAM", "THOC2", "THOC6", "THUMPD3", "TIA1", "TIAL1", "TMEM109", "TMF1", "TMX3", "TOP2A", "TOP2B", "TRA2A", "TRIM24", "TRMT1", "TTF2", "UBTF", "UPF2", "VARS2", "WARS2", "WDR43", "WDR48", "WRAP53", "YBX3", "YTHDC2", "YTHDF2", "ZCCHC3", "ZCRB1", "ZFR", "ZNF318", "ZNF512B"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/idx2term.json b/protein_atlas_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..788db72b689f2c5e97e2950ae30474cb590c326b --- /dev/null +++ b/protein_atlas_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Ribosomal proteins", "1": "RNA polymerase related proteins", "2": "CD markers", "3": "Plasma proteins", "4": "Predicted membrane proteins", "5": "Citric acid cycle related proteins"} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/plot_0.png b/protein_atlas_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..71089bc20dbe53a1ea3238d85cc29615857efb72 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:590218a0f0bae3aa4bdee4890ffb7bd6f1269729b382e43c71071d75dc1c5aad +size 132189 diff --git a/protein_atlas_protein_class/basic/plot_1.png b/protein_atlas_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..161aa534b28d7f3d7186741cf14367d5525be9a7 --- /dev/null +++ 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sha256:39b743ee79ba306d779f7669110443ed0e4f52f695d78a89391d7293f3e30b05 +size 146775 diff --git a/protein_atlas_protein_class/basic/plot_4.png b/protein_atlas_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..36717580b1d4852f0b57d86c979b679bb6976376 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9cd1998bb75b0e3954865e76ef9c78f29e7341f0b3ecd48baae010dff5433d80 +size 142431 diff --git a/protein_atlas_protein_class/basic/plot_5.png b/protein_atlas_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..82a3e9abe70ccff252fdf39390ec761717186605 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e67d523318cd326941fe3a5a19b7328dcee44bbe67a43589186e9494dfa26cc +size 149612 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..79d9d41670507b7765e2d5564db31f17d469f977 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:773723dcb046d8697915b1afda9867411a7da18e0fbbbbc9e7941cf5e27cb7c0 +size 85588 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e7bc46783ea9042bfd9bc60fc82c6a37d188b6f0 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3319, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 528.55 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..88e984a2806066a5f04824f49ea417d12d4df4db --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C345/C345_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..98597acb20db70660cf7362e463e62ed85ceafce --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosomal proteins 0.5466478888892148 1.8205068656801813 0.0686818516628839 0.7590309196123373 0.3434092583144199 129 Q7Z7F7,P83731,Q5T653,Q02878,P62424,P61513,P18077,P82914,Q9Y3U8,P55769,P50914,P62701,P62280,P62269,P62750,P62857,Q9Y3D3,Q9UHA3,P39019,Q9BYD6,P82912,P62277,Q96EY7,P46776,P62081,O76021,P26373,P63173,P62841,O95478,P61353,P36578,P62910,P62847,P82675,Q8N983,Q9H2W6,P83881,P62899,Q9Y2R9,P84098,P39023,P32969,P60866,P62917,P49406,Q6DKI1,P82664,P47914,Q92665,P61313,Q9NX20,P62244 53 +RNA polymerase related proteins 0.5174228142797805 1.166027434904152 0.2436033534035306 0.9962416960918844 0.8120111780117689 13 P62875,Q9GZS1,O15160,P19388,O95602,P62487,Q9H9Y6 7 +CD markers 0.3787714887464737 0.4590298347507711 0.6462127415775021 0.9999999990562788 1.0 19 P35613,Q13740,Q9Y624,Q9UBG0,P08195,P78536 6 +Plasma proteins 0.1321488126996838 0.4144673676353446 0.6785318607419413 0.999999999861082 1.0 1306 O15164,P81605,Q96T37,O43491,O60664,Q92614,P05141,P00505,P22087,P50213,P48047,Q16775,Q13740,Q9Y3Y2,O15020,Q9ULV3,Q14126,Q9UI26,Q9Y3A5,Q15022,Q07021,P11047,P43487,Q00403,Q9Y6I3,O15143,Q15428,P08621,Q8TCT8,Q9Y5A9,P10586,O94906,P46087,P49750,P50995,Q9BRK5,P52272,Q13576,Q8TDN6,P42858,P46013,Q7Z478,Q9BWJ5,Q96CX2,Q9NPF5,Q92879,O94919,P07305,Q9BQ39,Q8N2G8,Q9BPU6,P17655,P35080,Q13868,Q9BYT8,Q9NR30,Q9Y4C8,Q12905,P10321,P82094,O00625,O00116,O15213,P62847,P04439,P08574,P08579,P55145,P17480,P14174,P78347,P28838,P05165,P23786,P54132,P22033,Q99575,Q96RQ3,Q5JRA6,Q14165,Q15427,P34896,Q8N122,Q07960,Q96IU4,Q9BZK7,Q9P2R7,P62820,Q9UH99,Q9Y613,Q9UIJ7,Q16795,P16403,P04406,O15439,P09874,Q9H3P7,P50914,P38117,P62701,P11498,P62280,Q9Y624,P46939,P40939,Q9H2U2,Q99798,P39019,Q96I99,Q8NDI1,Q96S52,Q99797,Q99653,Q9NQ55,Q9P0L0,Q9UBU8,Q8TDD1,Q9Y6M1,P60953,Q5T8P6,P57678,O00487,P08069,P13667,P14923,P15531,Q16706,P30048,P52758,Q03518,P09622,P61160,Q13330,Q86Y39,P61247,Q16513,Q14839,Q14344,P84085,P42126,P62318,P61604,P62314,Q9Y2Q3,Q9H9Y6,Q99536,Q9Y2L1,Q9NR09,O15347,P84098,P62140,Q6P2Q9,Q96KM6,O43396,O75475,P30046,O95602,P39656,P61011,P67870,P61313,P50748,P08195,O75683,Q12906,Q9Y237,P50454,Q9BQG0,Q99986,Q969N2,O75367,Q12824,P04844,O43808,Q5GLZ8,P62424,Q00325,Q9HAU5,Q9UQR0,Q9NTX5,Q9UKA9,Q9UKX7,Q96L73,Q15233,Q8NFW8,Q9UMS4,Q9UNY4,Q15257,Q5JTV8,Q86U42,P52789,P30405,P30038,P09012,O00567,O60306,O75368,O75340,P11388,P20020,P25788,P30050,P33992,P11766,P59998,Q06124,Q14746,Q13601,Q07820,Q04446,O15144,P82979,P62136,Q96QK1,Q96HE7,Q92522,Q92974,Q15424,Q8NE71,Q7L014,Q9NXH9,Q15185,Q15031,Q13148,P51148,Q04760,O95478,P17066,P36578,O75380,Q9NZJ4,P62910,Q9UHV9,Q9Y296,Q02952,P62899,Q9Y617,Q9BY67,Q14697,Q9BZJ0,Q15075,O95793,Q14690,Q9UBC2,P15924,Q13435,O15269,Q9Y281,Q9Y3C6,O15400,O75390,P49406,O75489,O60333,O60725,P04179,Q8NI27,P83731,P09234,P42574,P62269,P62750,Q09666,Q96ST3,Q9H0A0,Q9NVP1,Q5VZE5,O60762,Q15056,P62277,Q02218,Q99996,Q9BUN8,Q9BUJ2,Q9H078,Q8N9N2,P33240,O60832,P26373,P20674,P62875,Q14151,Q14684,Q92620,Q9BY44,Q9H0S4,Q10567,Q9P2E9,Q9Y2P8,Q13308,P23368,P25325,P35251,P39023,P32969,P60866,P62917,O75083,P78406,P80723,Q02880,Q86XP3,Q92665,Q15637,P22061 305 +Predicted membrane proteins 0.237654929609018 0.2309383456734164 0.8173627002654584 0.9999999999999984 1.0 547 O43491,P05141,Q8N2F6,Q9H6K4,Q13740,Q8WVC6,Q9NPL8,Q92544,Q7RTS9,Q9BU23,Q14126,Q9NTJ5,P41440,Q8N511,Q96JJ7,O43909,O96005,Q8TCT8,P10586,Q8IUX1,P48651,P42858,Q9H6H4,Q8IXB1,Q5VZ89,O94919,O14548,Q96A57,P35080,Q92604,Q9Y320,Q7Z3C6,P10321,P04439,P08574,P03915,P46977,P57088,Q86Y07,Q99720,Q5JRA6,Q14165,Q86UE4,Q8N122,P35613,Q07960,Q9BT22,Q9NX47,Q9HCL2,Q9HCU5,Q9NX62,Q9BVC6,Q9BSK2,Q9UH99,Q16795,P62244,Q14534,O75438,O60831,O15439,Q9BXS4,Q9Y624,Q8N5M9,Q9ULK4,Q96S52,P09669,O95140,Q9H2V7,Q8NE86,Q9UBG0,Q96IX5,Q8TB61,Q16706,Q03518,Q86Y39,O43324,Q6NUK4,P78536,Q15125,O95139,Q96DI7,Q9Y673,P08195,Q99986,Q969N2,P04844,O43808,O43676,Q00325,Q5VV42,Q5JTV8,Q567V2,Q13724,O94901,O75787,Q6ZXV5,Q86XL3,Q9NP72,Q8N201,Q07820,O95563,O14828,Q9BTX1,Q9NS69,Q9BY67,Q9H2H8,O43819,O60725,O95168,P54709,Q8WVX9,Q9P0J0,P56134,Q12789,Q96ER9,Q9UDW1,O75396,Q96A26,Q99590,Q9BUN8,O43760,Q4G176,Q9P2E9,Q9Y5Q9,Q13308,Q05086,P60468,P32969,Q6P4A7,Q7LG56,Q86Y82,Q8TBP6,Q9Y3E5,Q99595,Q9P0I2,P22061 136 +Citric acid cycle related proteins 0.3012737781026058 0.1991586173897839 0.8421386694581323 1.0 1.0 25 P36957,P31040,P10515,P09622,P50213,Q02218,P11498,P08559,P11177,Q96I99,Q99798,Q9P2R7,O75390 13 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8bb0ad490df76db723e696894467dc87508c5964 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf50", "C20orf27", "C21orf59", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC88A", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CDV3", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A1", "FAM114A2", "FAM118B", "FAM160A2", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1211", "KIAA2013", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", 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"ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCC4", "ABCF1", "ABHD14B", "ACBD3", "ACO2", "ACSF3", "ACTR2", "ADAM17", "ADH5", "AGPS", "AHNAK", "AK3", "AKAP12", "AKAP9", "ALCAM", "ALDH4A1", "ALG1", "ALG5", "ANKLE2", "ANXA11", "AP1B1", "AQR", "ARF5", "ARHGAP1", "ARHGEF2", "ARMC10", "ARPC1B", "ARPC2", "ARPC4", "ASCC1", "ATG9A", "ATP1B3", "ATP2B1", "ATP5J2", "ATP5O", "ATP6AP2", "BASP1", "BIRC6", "BLM", "BRIX1", "BSG", "C1QBP", "CADM1", "CAPN2", "CASP3", "CCDC51", "CDC42", "CDKAL1", "CELF1", "CFL2", "CHD4", "CHP1", "CHTOP", "CIZ1", "CLPB", "CLPTM1", "CMAS", "COG2", "COX5A", "COX6C", "COX7A2L", "CPT2", "CRNKL1", "CS", "CSNK2B", "CSTF2", "CYC1", "DCAKD", "DCD", "DDOST", "DDT", "DDX18", "DDX21", "DDX42", "DDX46", "DDX47", 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--- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Nucleoli rim 29 59 2.678843997437101 0.0073876804116217 26.29126213592233 54.949029126213595 -1.3176841375773052 0.3549913093662085 8.899253888177155 3.655667767234105 1.3959886459077675 0.3583848194117569 1.0 0.1074078448971524 0.0248688197494626 3.677161933476459e-06 +Mitotic chromosome 19 36 2.276122491199745 0.022838679285035 18.98543689320388 35.75728155339806 -1.3453226058379633 0.3101380062519321 6.50353015067777 1.776141883039992 1.344647045652705 0.3392315165259217 1.0 0.0191373699896123 0.0135656277048388 1.9159873565214744e-05 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 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0000000000000000000000000000000000000000..eec708af009d16a4e0927c50c15f603c51da66e6 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nucleoli rim 0.5017364500551785 2.678843997437101 0.0073876804116217 0.2228435146742019 0.1255905669975696 59 Q14137,Q8NEF9,O00541,P16403,Q9NX58,Q9UHA3,Q9NVP1,Q15022,Q8WTT2,Q06124,Q13823,Q13610,Q13601,P46013,Q92522,O76021,Q1ED39,Q9NR30,Q14684,Q9H6W3,Q9BYG3,Q99848,Q9UNQ2,Q6UXN9,Q9BZE4,Q9H7B2,Q13895,O75683,Q8IY81 29 +Mitotic chromosome 0.5985360385584092 2.276122491199745 0.022838679285035 0.5441173059481886 0.2588383652303969 36 Q14137,Q9NY93,Q9NVP1,Q8TDN6,Q96B26,P46013,P42696,O76021,Q9NR30,Q14684,Q9BYG3,Q99848,Q9H7B2,Q7L5D6,Q9UMY1,Q13895,O75683,Q8IY81,Q9Y237 19 +Nucleoli fibrillar center 0.3170640015076306 0.7347193977616442 0.4625104041725749 0.9999999993198854 1.0 62 Q12824,O95486,P22087,Q5GLZ8,P53365,P62750,Q9P016,Q15233,O00567,O15446,Q9GZS1,O15160,Q9H2V7,Q06210,Q96B26,O60832,Q9H9Y6,P17480,P78406,O60333,O60264,O95602,Q9BT22,Q9H583 24 +Nuclear membrane 0.2752451595942234 0.3523471198680421 0.7245779544358726 1.0 1.0 67 P56134,Q5SNT2,P04406,P37198,Q9UI10,P49790,Q5JTV8,O94901,Q9Y3D9,Q9BQ75,Q6BDS2,Q9BW91,O94919,Q9BTX1,Q9Y5Q9,Q9BZE4,Q6UW68,O95168,Q8NFH5,Q9BVC6,Q9UH99,Q9Y6D9 22 +Actin filaments 0.2520440983040961 0.2769816169161813 0.7817942217030598 1.0 1.0 46 Q9UI10,P62312,P07305,Q9BTX1 4 +Lipid droplets 0.3018278691265249 0.1934570249706879 0.8466010593482334 1.0 1.0 9 O60664,Q8NBQ5 2 +Mitochondria 0.3502169536229217 0.1928678996582137 0.8470624253604164 1.0 1.0 412 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145 +Nuclear speckles 0.307846828116114 0.1614331003618235 0.8717522982374695 1.0 1.0 127 O75438,Q7Z6E9,Q15233,Q9Y3Y2,Q9UMS4,Q5SSJ5,Q9BY77,Q86U42,Q8WXA9,Q86W42,P10412,Q13247,O95391,Q9ULX6,O94906,Q9UBU8,P49750,Q8TF01,P82979,Q12972,Q9BU76,Q5T8P6,Q9ULR0,Q7L014,Q9UNP9,Q16539,Q9P2N5,P08579,Q13435,Q9UNM6,O75152,Q6NSI4,Q96BK5,Q96DI7,Q15427,Q86XP3,O95400 37 +Nucleoli 0.3391090859364318 0.1592823284235399 0.8734464428838331 1.0 1.0 292 Q9NQE9,Q9GZZ1,Q15022,Q9NVU7,O60884,P46087,Q8NHQ9,Q8TDN6,Q5SRE5,Q9BQ39,P42696,O14548,Q1ED39,Q13868,Q9Y4C8,Q99848,O15213,Q99547,Q15435,P23786,Q99575,Q96BK5,P47914,Q7L5D6,Q96DE0,Q96IU4,Q9BUQ8,Q9NW13,Q14137,Q9BSC4,O00541,Q13503,O15226,P09874,O15439,Q9NX58,Q9H501,Q7L590,Q9BQ75,Q8TDD1,O43709,Q9NZM5,Q9H6R0,P61353,Q9H7B2,Q9GZR2,P84098,O75683,Q8IY81,Q9Y237,Q9NUL7,P62424,Q9UQR0,Q9NY93,Q8NFW8,Q9UHA3,Q8WTT2,Q92522,Q96C57,O95478,P36578,Q96GN5,Q9H2H8,Q9Y3C6,Q6DKI1,P17096,Q969S3,Q53HL2,Q12789,Q99584,Q9H0A0,Q9H0U9,Q9NVP1,Q13595,Q13823,P26373,Q12788,Q14684,Q15120,Q9BYG3,Q9H0S4,Q9UNQ2,Q9BZE4,P05204,P39023,P32969,P62917,Q92665,Q9H9Y2,Q9UMY1,Q13895,Q06265 92 +Endoplasmic reticulum 0.2440492223188927 0.1339039340324763 0.8934785393964675 1.0 1.0 201 P83731,P04844,O60831,P61513,Q9Y3U8,P62750,P62841,P50914,Q9UBM7,P62280,Q13724,P08708,P11047,Q86XL3,P62277,O96005,Q9NXN4,P48651,Q9P0L0,Q9UBW7,P62854,P46776,P62081,P62753,P62266,Q9BUN8,Q9H6H4,Q96AG4,P13667,P26373,Q96A57,O60826,Q03518,Q96S66,Q13162,P61247,P63173,P36578,Q9P2E9,P62910,P62847,Q14697,O75477,P83881,P55145,O15269,P60468,Q86Y07,P84157,Q15125,O94874,P32969,P60866,P62917,Q6UW68,P47914,Q86UE4,Q9BT22,P39656,Q9HCU5,Q15738,P50454,P62820 63 +Cytoplasmic bodies 0.2485340686095664 0.1071921309599592 0.9146365580460852 1.0 1.0 20 Q9Y5A9,Q8NHU6,Q9BY77 3 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..41e7e3c4abc36f533de6a56be6f8f08a8b4e98c1 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Aggresome", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARVCF", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1B3", "ATP2B1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B4GALT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKN2AIP", "CDR2L", "CDS2", "CDV3", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN6", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "CORO1B", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOC", "ELP1", "ELP2", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A1", "FAM114A2", "FAM160A2", "FAM162A", "FAM177A1", "FAM208A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGT7", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IER3IP1", "IFIT5", "IFNGR1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1211", "KIAA2013", "KIF11", "KIF14", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL37", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KB", "PIBF1", "PICALM", "PIGL", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB11B", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCL1", "RCN1", "RCN2", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D13", "TBC1D15", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKFC", "TKT", "TLN1", "TM9SF3", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM165", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TTC1", "TTC19", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXN2", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR77", "WDR82", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "ABCC4", "ABHD11", "ABHD14B", "ACAD9", "ACO2", "ACSF3", "AGK", "AK3", "AKAP8L", "ALDH4A1", "ALG1", "ANKLE2", "ARFIP2", "ARMC1", "ARMC10", "ATP5J2", "ATP5O", "ATPAF1", "ATPIF1", "BCAT2", "BOP1", "BRIX1", "BUD23", "BYSL", "C12orf43", "C12orf73", "C1QBP", "C1orf35", "CASP3", "CCDC22", "CCDC51", "CD2BP2", "CD3EAP", "CDCA7L", "CDCA8", "CHTOP", "CIAPIN1", "CLCC1", "CLPTM1", "CMAS", "CMSS1", "COQ8A", "COX6C", "COX7A2L", "CPT2", "CXorf57", "CYC1", "DDOST", "DDT", "DDX18", "DDX21", "DDX23", "DDX28", "DDX42", "DDX46", "DDX47", "DDX49", "DDX50", "DDX54", "DDX55", "DDX56", "DERL1", "DHCR7", "DHRS7", "DHX33", "DIMT1", "DKC1", "DLAT", "DLD", "DLST", "DNAJA2", "EBNA1BP2", "EBP", "ECI1", "EIF2A", "EIF2B4", "ENDOD1", "ERAL1", "ERLIN1", "ESF1", "ETFB", "EXOSC2", "EXOSC8", "EXOSC9", "FAHD1", "FAM160A2", "FAM162A", "FASTKD2", "FBL", "FDXR", "FOXRED1", "FTSJ3", "GANAB", "GAPDH", "GCDH", "GDAP1", "GDAP2", "GET4", "GFM1", "GFPT1", "GNL2", "GPAM", "GPN1", "GPT2", "GTF3C1", "GTF3C3", "GTPBP3", "GTPBP4", "H1F0", "H1FX", "HADHA", "HADHB", "HCCS", "HDHD5", "HEATR1", "HERC4", "HINT3", "HIST1H1C", "HIST1H1E", "HMGA1", "HMGN2", "HP1BP3", "HSD17B11", "IBA57", "IDH3A", "ILF3", "ISOC2", "ISY1", "IVD", "KCTD12", "KIF1B", "KNOP1", "KRR1", "LAMC1", "LARS2", "LETM1", "LRRC59", "LSM6", "LYAR", "MAD1L1", "MANF", "MAPK14", "MARCH5", "MCCC1", "MCL1", "MCM10", "MCU", "ME2", "MED21", "MFN2", "MGME1", "MIPEP", "MKI67", "MOGS", "MORF4L1", "MPHOSPH6", "MPST", "MRPL1", "MRPL19", "MRPL2", "MRPL43", "MRPL46", "MRPL50", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS23", "MRPS31", "MRPS5", "MRPS7", "MTDH", "MTHFD1L", "MTX3", "MUT", "MXRA7", "NAA50", "NADK2", "NAT10", "NDC1", "NDUFA11", "NDUFA13", "NDUFA9", "NDUFB1", "NDUFB4", "NDUFB6", "NDUFS1", "NDUFV2", "NIFK", "NKRF", "NLN", "NOC3L", "NOL10", "NOL7", "NONO", "NOP2", "NOP53", "NOP56", "NSA2", "NSDHL", "NUDT16", "NUDT9", "NUP153", "NUP188", "NUP35", "NUP62", "OGDH", "OXCT1", "PABPN1", "PARP1", "PC", "PCCA", "PDHA1", "PDIA4", "PDK3", "PES1", "PIN4", "PINX1", "PLIN3", "PNISR", "PNPT1", "POLDIP2", "POLDIP3", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POP1", "PPA2", "PPIE", "PPIF", "PPIL1", "PPIL3", "PPP1R7", "PPP1R8", "PRAF2", "PRDX3", "PRDX4", "PREB", "PRPF19", "PRPF6", "PSMD13", "PTCD1", "PTCD3", "PTDSS1", "PTPN11", "PTRH2", "PWP1", "RAB1A", "RAE1", "RARS2", "RBBP6", "RBM19", "RBM26", "RBM27", "RBM28", "RBM34", "REEP4", "REXO4", "RIOX1", "RPF1", "RPF2", "RPL13", "RPL14", "RPL19", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL29", "RPL3", "RPL32", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN2", "RPS11", "RPS13", "RPS15", "RPS17", "RPS20", "RPS23", "RPS24", "RPS26", "RPS3A", "RPS6", "RPS7", "RRBP1", "RRP1B", "RSL1D1", "RSL24D1", "S100A13", "SARNP", "SARS2", "SCML2", "SCO2", "SDAD1", "SEC24A", "SEC61B", "SERPINH1", "SF3B2", "SF3B4", "SFXN2", "SFXN4", "SLC25A3", "SLC25A5", "SLU7", "SMARCA5", "SMARCB1", "SNRNP40", "SNRPB2", "SOD2", "SPNS1", "SPTLC1", "SREK1", "SRFBP1", "SRSF6", "SUCLA2", "SUCLG2", "SUN1", "SUN2", "SUPV3L1", "SURF6", "SUZ12", "TACO1", "TAP1", "TBL3", "TBRG4", "TDRD7", "TFAM", "THOC6", "THYN1", "TIMM17A", "TIMM8A", "TIMMDC1", "TMEM109", "TMEM126B", "TMEM201", "TMEM205", "TMEM230", "TOMM22", "TOMM5", "TOR1AIP1", "TRA2A", "TSPYL1", "UBTF", "UFL1", "UHRF1BP1", "UQCC2", "UQCRQ", "USMG5", "VAPA", "VARS2", "VRK2", "WARS2", "WDR46", "WDR82", "XPNPEP3", "YLPM1", "YTHDF2", "ZC3H11A", "ZMYM2", "ZNF622"]} \ No newline at end of file