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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +4 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/basic/idx2term.json +1 -0
  11. interpro_binding_site/basic/plot_0.png +3 -0
  12. interpro_binding_site/consensus.joblib +3 -0
  13. interpro_binding_site/df_merge.tsv +1 -0
  14. interpro_binding_site/metrics.json +7 -0
  15. interpro_binding_site/paths.json +1 -0
  16. interpro_binding_site/result.tsv +4 -0
  17. interpro_binding_site/selections.json +1 -0
  18. interpro_conserved_site/advanced/idx2term.json +1 -0
  19. interpro_conserved_site/advanced/plot_0.png +3 -0
  20. interpro_conserved_site/basic/idx2term.json +1 -0
  21. interpro_conserved_site/basic/plot_0.png +3 -0
  22. interpro_conserved_site/basic/plot_1.png +3 -0
  23. interpro_conserved_site/consensus.joblib +3 -0
  24. interpro_conserved_site/df_merge.tsv +2 -0
  25. interpro_conserved_site/metrics.json +7 -0
  26. interpro_conserved_site/paths.json +1 -0
  27. interpro_conserved_site/result.tsv +28 -0
  28. interpro_conserved_site/selections.json +1 -0
  29. interpro_domain/advanced/idx2term.json +1 -0
  30. interpro_domain/advanced/plot_0.png +3 -0
  31. interpro_domain/basic/idx2term.json +1 -0
  32. interpro_domain/basic/plot_0.png +3 -0
  33. interpro_domain/basic/plot_1.png +3 -0
  34. interpro_domain/basic/plot_2.png +3 -0
  35. interpro_domain/basic/plot_3.png +3 -0
  36. interpro_domain/basic/plot_4.png +3 -0
  37. interpro_domain/basic/plot_5.png +3 -0
  38. interpro_domain/basic/plot_6.png +3 -0
  39. interpro_domain/basic/plot_7.png +3 -0
  40. interpro_domain/consensus.joblib +3 -0
  41. interpro_domain/df_merge.tsv +5 -0
  42. interpro_domain/metrics.json +7 -0
  43. interpro_domain/paths.json +1 -0
  44. interpro_domain/result.tsv +182 -0
  45. interpro_domain/selections.json +0 -0
  46. interpro_family/advanced/idx2term.json +1 -0
  47. interpro_family/advanced/plot_0.png +3 -0
  48. interpro_family/advanced/plot_1.png +3 -0
  49. interpro_family/basic/idx2term.json +1 -0
  50. interpro_family/basic/plot_0.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
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+ {}
interpro_active_site/basic/idx2term.json ADDED
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+ {}
interpro_active_site/consensus.joblib ADDED
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interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2948,
4
+ "annotations_size": 56,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.517857142857143
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+ }
interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C350/C350_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,4 @@
 
 
 
 
 
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Serine carboxypeptidase, serine active site [IPR018202] 0.919524617996604 1.8797355008655887 0.0601441347145059 0.968995099785492 0.414700645471299 3 Q9HB40,Q9H3G5 2
3
+ Histidine acid phosphatase active site [IPR033379] 0.9005431093007401 1.3610156344417177 0.1735087487208677 0.9999768077650169 0.4670136870840963 2 Q9NPH0 1
4
+ ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.3768992414808112 0.1442739875566896 0.8852841183095923 1.0 0.9533828966410992 4 P06576 1
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK3", "MAPKAPK2", "MARK2", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "YES1"], "leading_proteins": ["ACP6", "ATP5B", "CPVL", "SCPEP1"]}
interpro_binding_site/advanced/idx2term.json ADDED
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interpro_binding_site/basic/idx2term.json ADDED
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+ {"0": "EF-Hand 1, calcium-binding site [IPR018247]"}
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interpro_binding_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_binding_site/metrics.json ADDED
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+ {
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+ "signature_size": 2948,
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+ "title": "Average number of proteins per term",
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interpro_binding_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C350/C350_val_log2fc"}
interpro_binding_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ EF-Hand 1, calcium-binding site [IPR018247] 0.4719640947753307 1.8752217053661928 0.0607622292964586 0.8376355585543633 0.293684108266217 36 Q03001,P43304,O75746,P19174,Q9BPX6,Q02818,O43852,Q6NUK1,P80303,O95202,Q14257,P0DP25,Q96AY3,Q9UM19,Q9H223,Q9NWM8,Q9Y680,Q8IXI1 18
3
+ Beta tubulin, autoregulation binding site [IPR013838] 0.4940536867142422 0.6249171246109887 0.5320254524419157 0.9999999997268226 0.7554810305466693 5 P07437,P04350,Q9BVA1,Q9BUF5 4
4
+ Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.4616429056347553 0.0499135108311923 0.960191310638088 1.0 1.0 2 P34897 1
interpro_binding_site/selections.json ADDED
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1
+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK2", "CDK4", "CDK5", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "HPCAL4", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CALU", "DST", "EHD4", "FKBP10", "FKBP14", "FKBP7", "GPD2", "HPCAL4", "LETM1", "MICU1", "NUCB1", "NUCB2", "PLCG1", "RCN2", "RHOT2", "SHMT2", "SLC25A12", "SLC25A24", "TUBB", "TUBB2B", "TUBB4A", "TUBB6"]}
interpro_conserved_site/advanced/idx2term.json ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_conserved_site/metrics.json ADDED
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+ {
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+ "title": "Average number of proteins per term",
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interpro_conserved_site/paths.json ADDED
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interpro_conserved_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Syntaxin/epimorphin, conserved site [IPR006012] 0.8361658735553849 2.373472452999737 0.0176217074539259 0.9911661614035512 0.6741545893868098 6 O60499,O15400,O43752,Q9P2W9,Q13190 5
3
+ Intermediate filament protein, conserved site [IPR018039] 0.6971044113799343 1.7599876030516308 0.0784099085342442 0.9999999996309764 0.6741545893868098 7 P20700,Q03252,P07197,P08670,Q16352 5
4
+ Tetraspanin, conserved site [IPR018503] 0.9877800407331974 1.7187678365138834 0.0856566542651922 0.9999999999548064 0.6741545893868098 2 O43657 1
5
+ Haem oxygenase conserved site [IPR018207] 0.9867617107942972 1.714604334768892 0.0864177934665386 0.9999999999637864 0.6741545893868098 2 P09601 1
6
+ Thioredoxin, conserved site [IPR017937] 0.6243931582343532 1.5235623041914068 0.1276180857522422 0.9999999999999998 0.7205766713255528 11 Q9H1E5,Q9H3N1 2
7
+ Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.7949066213921809 1.377723080399081 0.168288802531485 1.0 0.7364415446859321 3 P04439,P55899 2
8
+ Ras GTPase-activating protein, conserved site [IPR023152] 0.6368885869565323 1.1440835642472058 0.2525889831569086 1.0 0.7814155179465248 4 P46940,P21359,Q9UJF2 3
9
+ Heavy-metal-associated, conserved site [IPR017969] 0.793618465716222 0.929152324038232 0.352810151114665 1.0 0.8400456628413644 2 P35670 1
10
+ Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.7854718262050211 0.8972107358319245 0.3696064775591936 1.0 0.840301906245688 2 Q07820 1
11
+ Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.7854718262050211 0.8972107358319245 0.3696064775591936 1.0 0.840301906245688 2 Q07820 1
12
+ Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.7854718262050211 0.8972107358319245 0.3696064775591936 1.0 0.840301906245688 2 Q07820 1
13
+ Guanylate kinase, conserved site [IPR020590] 0.5611340984464795 0.8105097343800829 0.4176472726145528 1.0 0.9032046708574882 4 Q14168 1
14
+ ABC transporter-like, conserved site [IPR017871] 0.4661496177156982 0.6344882968249435 0.5257622020748345 1.0 0.957895518848671 9 O75027,Q03519 2
15
+ Glycoside hydrolase, family 29, conserved site [IPR018526] 0.7067209775967358 0.6028165678710131 0.5466307237584689 1.0 0.9758642450990116 2 Q9BTY2 1
16
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.4444279987149415 0.5159234000057152 0.6059079100619817 1.0 0.984127802164422 8 P49721,P20618 2
17
+ HMG box A DNA-binding domain, conserved site [IPR017967] 0.5684210526315849 0.4948106351271134 0.6207337964750541 1.0 0.984127802164422 3 P26583,P09429 2
18
+ DnaJ domain, conserved site [IPR018253] 0.438277948832504 0.4865615359978464 0.6265690871214087 1.0 0.984127802164422 8 Q96KC8 1
19
+ Dynamin, GTPase region, conserved site [IPR019762] 0.6680244399185297 0.471981458597775 0.6369400230914388 1.0 0.984127802164422 2 P50570 1
20
+ 3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.6133740665308816 0.3102273947916463 0.756388039466751 1.0 0.984127802164422 2 Q16836 1
21
+ S100/Calbindin-D9k, conserved site [IPR001751] 0.5563475899524662 0.1779100691090643 0.8587936029972514 1.0 0.984127802164422 2 P60903 1
22
+ Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.4522920203735205 0.163489860037384 0.8701327562575505 1.0 0.984127802164422 3 Q9Y2T2,Q96CW1 2
23
+ Heat shock protein Hsp90, conserved site [IPR019805] 0.4431239388794658 0.1444033281324894 0.8851819888857215 1.0 0.984127802164422 3 P07900,P14625 2
24
+ Oxysterol-binding protein, conserved site [IPR018494] 0.3547400611620834 0.1064076366217999 0.9152589343309598 1.0 0.984127802164422 5 Q96SU4,Q9BZF1,Q9H4L5,Q9BXB4 4
25
+ Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.4193548387096864 0.1004437951322381 0.9199920020589358 1.0 0.984127802164422 3 Q16539,P28482 2
26
+ Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.4142614601018732 0.0920661560946847 0.9266454777401336 1.0 0.984127802164422 3 Q99536,Q8N4Q0 2
27
+ Ribosomal protein L24e, conserved site [IPR023442] 0.4928716904276947 0.0800071601719758 0.9362315612353348 1.0 0.984127802164422 2 Q9UHA3 1
28
+ Cyclic nucleotide-binding, conserved site [IPR018488] 0.3214528173794984 0.0056684483459302 0.9954772568013616 1.0 0.9954772568013616 2 P10644 1
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARHGEF7", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", "DTX3L", "DUS2", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRPL13", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASAL2", "RCL1", "RDH13", "RDX", "REL", "RIDA", "RIOK1", "RIOK2", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A8", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPTBN1", "SPTBN2", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP2", "TBL3", "TCP1", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB7", "AP2M1", "AP3M1", "ATP7B", "DNAJC1", "DNM2", "FCGRT", "FUCA2", "HADH", "HLA-A", "HMGB1", "HMGB2", "HMOX1", "HSP90AA1", "HSP90B1", "INA", "IQGAP1", "LMNB1", "LMNB2", "MAPK1", "MAPK14", "MCL1", "MPP2", "NEFM", "NF1", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "PRKAR1A", "PSMB1", "PSMB2", "RASAL2", "RSL24D1", "S100A10", "STX10", "STX18", "STX5", "STX6", "STX7", "TAP2", "TMX1", "TMX4", "TSPAN6", "VAT1", "VIM", "ZADH2"]}
interpro_domain/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]"}
interpro_domain/advanced/plot_0.png ADDED

Git LFS Details

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interpro_domain/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "1": "EF-hand domain [IPR002048]", "2": "Intermediate filament, rod domain [IPR039008]", "3": "Immunoglobulin-like domain [IPR007110]", "4": "Zinc finger, RanBP2-type [IPR001876]", "5": "RNA recognition motif domain, eukaryote [IPR003954]", "6": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "7": "Importin-beta, N-terminal domain [IPR001494]"}
interpro_domain/basic/plot_0.png ADDED

Git LFS Details

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  • Size of remote file: 143 kB
interpro_domain/basic/plot_1.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 128 kB
interpro_domain/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: 5ddb4b1dca315b5a2ea0545ad9768eebb5766d0284da429cf9e95158d0bf79a8
  • Pointer size: 131 Bytes
  • Size of remote file: 135 kB
interpro_domain/basic/plot_3.png ADDED

Git LFS Details

  • SHA256: ace86cbc72776ca8e138b67e1d1c491eb24cf68348bcf1b136866881f064563e
  • Pointer size: 131 Bytes
  • Size of remote file: 135 kB
interpro_domain/basic/plot_4.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 145 kB
interpro_domain/basic/plot_5.png ADDED

Git LFS Details

  • SHA256: 68ca9644c94655409ff31cf2991573cf342ce2e7222a0390ba998466275b00ec
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interpro_domain/basic/plot_6.png ADDED

Git LFS Details

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interpro_domain/basic/plot_7.png ADDED

Git LFS Details

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  • Size of remote file: 149 kB
interpro_domain/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:373b12de58e9864307425e02fbfe370a7c38302e633ca3ce8d2c59c2cbf7285f
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+ size 88629
interpro_domain/df_merge.tsv ADDED
@@ -0,0 +1,5 @@
 
 
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ GOLD domain [IPR009038] 4 6 2.3511204922573627 0.0187169717805353 2.8762135922330097 6.247572815533981 0.4192390492462461 0.3068843884052658 1.4199402534298398 0.930533270242389 1.3963570929114475 0.294203492723015 0.0002148456595075 1.0 0.1191939669275513 0.0388074443523606 0.0002528551610256
3
+ Tim10-like [IPR004217] 4 5 2.194566663019242 0.0281946971068483 1.2005141388174807 2.5167095115681235 0.6297728943083764 0.3036466482483842 1.011959204869136 1.1903007636326162 1.51035532787006 0.2968335314780513 6.802332917000595e-05 1.0 1.0 0.0002725491832247 1.5702078168631558e-06
4
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 4 6 2.1451774950642206 0.0319386582510814 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0017883442570374 0.0014481500629001 0.0001833288791406 0.0026887292270871 0.0001620848202149
5
+ P-type ATPase, haloacid dehalogenase domain [IPR044492] 6 8 2.120382506381824 0.0339738007615642 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0030905554460515 1.0 1.0 0.099708835751112 0.0035916782285116
interpro_domain/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2948,
4
+ "annotations_size": 2456,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.1294788273615635
7
+ }
interpro_domain/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C350/C350_val_log2fc"}
interpro_domain/result.tsv ADDED
@@ -0,0 +1,182 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Reticulon [IPR003388] 0.9813179347826092 2.6155000679852236 0.0089096903501979 0.9999999997154932 0.8409611729477436 4 O75298,Q9NQC3,Q16799 3
3
+ GOLD domain [IPR009038] 0.8311507236735701 2.3511204922573627 0.0187169717805353 1.0 0.8409611729477436 6 Q15363,Q9Y3B3,Q9BVK6,P49755 4
4
+ Tim10-like [IPR004217] 0.8369011213047775 2.194566663019242 0.0281946971068483 1.0 0.8409611729477436 5 Q9Y5J9,Q9Y5L4,Q9Y5J7,O60220 4
5
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.785561347455134 2.1451774950642206 0.0319386582510814 1.0 0.8409611729477436 6 O43169,Q9UMX5,O00264,O15173 4
6
+ P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7651534426942244 2.120382506381824 0.0339738007615642 1.0 0.8409611729477436 8 P23634,P16615,P35670,P05023,P20020,Q9HD20 6
7
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 0.823707128872232 1.9648883776277464 0.049427158201567 1.0 0.8409611729477436 4 Q15629,Q96G23 2
8
+ EF-hand domain [IPR002048] 0.4933125062233197 1.950775933968327 0.0510837058704991 1.0 0.8409611729477436 43 Q6NUK1,P0DP25,Q96AY3,P43304,O75746,Q02818,P80303,Q9H223,Q8NF37,P19174,P14649,Q9BPX6,O43852,Q14257,Q9UM19,Q9Y680,Q8IXI1,Q03001,P60660,O95202,Q9NWM8,Q66K14,Q9UJS0 23
9
+ LEM domain [IPR003887] 0.7377296820360165 1.923777864226619 0.0543824331940518 1.0 0.8409611729477436 6 P42167,Q86XL3,P50402 3
10
+ Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.771809916439732 1.906786031025534 0.0565483009794578 1.0 0.8409611729477436 5 P23634,P16615,P05023 3
11
+ Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.771809916439732 1.906786031025534 0.0565483009794578 1.0 0.8409611729477436 5 P23634,P16615,P05023 3
12
+ MHC class I-like antigen recognition-like [IPR011161] 0.7951766304347909 1.84236489786764 0.065421792720776 1.0 0.8409611729477436 4 P04439,P55899,P10321 3
13
+ Target SNARE coiled-coil homology domain [IPR000727] 0.7126718540183591 1.8056626408909684 0.0709710515731678 1.0 0.8409611729477436 6 O60499,O43752,O15400,Q13190 4
14
+ ABC transporter type 1, transmembrane domain [IPR011527] 0.7458172758665192 1.789498584062235 0.0735345553145305 1.0 0.8409611729477436 5 O75027,Q03519 2
15
+ Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8946363147355636 1.7806000793821286 0.0749778068108513 1.0 0.8409611729477436 3 Q9Y282 1
16
+ Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8946363147355636 1.7806000793821286 0.0749778068108513 1.0 0.8409611729477436 3 Q9Y282 1
17
+ Immunoglobulin C1-set [IPR003597] 0.7431192660550334 1.7772509024126235 0.0755269677904437 1.0 0.8409611729477436 5 P04439,P55899,P10321,P01889 4
18
+ Intermediate filament, rod domain [IPR039008] 0.6971044113799343 1.7599876030516308 0.0784099085342442 1.0 0.8409611729477436 7 P20700,Q03252,P07197,P08670,Q16352 5
19
+ Metaxin, glutathione S-transferase domain [IPR033468] 0.8776778808729369 1.7126640235948374 0.0867743673764502 1.0 0.8409611729477436 3 Q13505 1
20
+ Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.8776778808729369 1.7126640235948374 0.0867743673764502 1.0 0.8409611729477436 3 Q13505 1
21
+ Syntaxin 6, N-terminal [IPR015260] 0.982688391038696 1.6979446355753482 0.0895182117183757 1.0 0.8409611729477436 2 O60499 1
22
+ Glycosyltransferase 2-like [IPR001173] 0.7578547406497623 1.680135875450791 0.0929308822002381 1.0 0.8409611729477436 4 Q10472,Q8N4A0 2
23
+ Major facilitator superfamily domain [IPR020846] 0.7554347826087052 1.6695466225754898 0.0950090987198515 1.0 0.8409611729477436 4 Q9H2V7,Q6NT16,Q9NY64 3
24
+ Choline/carnitine acyltransferase domain [IPR039551] 0.9596062457569569 1.603392353414806 0.1088480581760085 1.0 0.8409611729477436 2 P23786 1
25
+ Sterol-sensing domain [IPR000731] 0.9436524100475208 1.5379349132304652 0.1240645297182876 1.0 0.8409611729477436 2 P04035 1
26
+ Acyltransferase, C-terminal domain [IPR032098] 0.8329371816638284 1.5321657896341772 0.125481528239207 1.0 0.8409611729477436 3 Q9NUQ2,Q92604 2
27
+ SET domain [IPR001214] 0.7208641361124426 1.5174574543543575 0.1291512274828434 1.0 0.8409611729477436 4 Q03164 1
28
+ START domain [IPR002913] 0.9375424304141194 1.5128536993325084 0.130316825016747 1.0 0.8409611729477436 2 Q14849 1
29
+ Band 7 domain [IPR001107] 0.6455847374704202 1.5074508331587468 0.131695137423186 1.0 0.8409611729477436 7 Q99623,O75955,P35232,P27105 4
30
+ Fatty acid hydroxylase [IPR006694] 0.9317718940936828 1.4891631721991911 0.1364444060154408 1.0 0.8409611729477436 2 Q15800 1
31
+ Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.6364836347724154 1.4383661134555186 0.1503302021576669 1.0 0.8409611729477436 6 P50570,Q9H223,O60313,O95140 4
32
+ Dynamin, N-terminal [IPR045063] 0.6364836347724154 1.4383661134555186 0.1503302021576669 1.0 0.8409611729477436 6 P50570,Q9H223,O60313,O95140 4
33
+ Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7972835314091674 1.3873914857789755 0.1653224198180194 1.0 0.856607306061299 3 O15460,Q32P28 2
34
+ Immunoglobulin-like domain [IPR007110] 0.6039398906811296 1.3807635601755577 0.1673516711103102 1.0 0.8580703637722796 10 Q08722,P55899,P10586,P10321,P35613,P04439,P01889 7
35
+ MHC class I, alpha chain, C-terminal [IPR010579] 0.7949066213921847 1.3777230803990967 0.1682888025314801 1.0 0.8592875239445223 3 P04439,P10321 2
36
+ MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.7949066213921847 1.3777230803990967 0.1682888025314801 1.0 0.8592875239445223 3 P04439,P10321 2
37
+ N-acetylgalactosaminyltransferase [IPR045885] 0.7856725196511147 1.3401527536776547 0.1801956882463686 1.0 0.8633059516306977 3 Q8N4A0 1
38
+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6803790177584341 1.3378243814221562 0.180953691997292 1.0 0.8633059516306977 4 O15460,Q32P28 2
39
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6803790177584341 1.3378243814221562 0.180953691997292 1.0 0.8633059516306977 4 O15460,Q32P28 2
40
+ Peptidase M48 [IPR001915] 0.8927359131025066 1.329026659612781 0.1838391745532797 1.0 0.8633059516306977 2 O75844 1
41
+ Ricin B, lectin domain [IPR000772] 0.675367123896538 1.315512171008129 0.1883378296251572 1.0 0.8652280730874293 4 Q8N4A0 1
42
+ Longin domain [IPR010908] 0.7786078098471936 1.3114039059801108 0.1897213399083661 1.0 0.8652280730874293 3 O15498,O75396 2
43
+ v-SNARE, coiled-coil homology domain [IPR042855] 0.7786078098471936 1.3114039059801108 0.1897213399083661 1.0 0.8652280730874293 3 O15498,O75396 2
44
+ Zinc finger, CHHC-type [IPR012996] 0.7694397283531424 1.2740986237945229 0.2026284661048665 1.0 0.8652280730874293 3 P55795,P52597 2
45
+ Intermediate filament head, DNA-binding domain [IPR006821] 0.7646859083191768 1.2547601379917397 0.2095658472121591 1.0 0.8652280730874293 3 P08670,Q16352 2
46
+ Exportin-2, central domain [IPR013713] 0.7616298811544935 1.2423311865849758 0.2141143933474154 1.0 0.8652280730874293 3 O15397,P55060 2
47
+ GMP phosphodiesterase, delta subunit [IPR008015] 0.7614143885775033 1.2414548749968193 0.214437758192362 1.0 0.8652280730874293 3 Q13432 1
48
+ ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8682959945689066 1.2291456710259527 0.219017194247336 1.0 0.8661936055901083 2 Q5T9A4 1
49
+ FAD linked oxidase, N-terminal [IPR006094] 0.864562118126266 1.2139321164234271 0.2247736475542541 1.0 0.8682149204424569 2 Q15392 1
50
+ FAD-binding domain, PCMH-type [IPR016166] 0.864562118126266 1.2139321164234271 0.2247736475542541 1.0 0.8682149204424569 2 Q15392 1
51
+ RBM3/CIRBP, RNA recognition motif [IPR034278] 0.8536999321113361 1.169764492777954 0.2420957563845789 1.0 0.8782676184350455 2 P98179 1
52
+ CNNM, transmembrane domain [IPR002550] 0.8496266123557354 1.1532402534549622 0.248811785606104 1.0 0.8856257180414371 2 Q6P4Q7 1
53
+ Ion transporter-like, CBS domain [IPR044751] 0.8496266123557354 1.1532402534549622 0.248811785606104 1.0 0.8856257180414371 2 Q6P4Q7 1
54
+ Phospholipid/glycerol acyltransferase [IPR002123] 0.6078599091711346 1.1497169331144033 0.2502604777274193 1.0 0.8860812333173556 5 Q9NUQ2,Q92604,Q8NF37 3
55
+ Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7361988101789307 1.1390648465328024 0.2546761083179336 1.0 0.8860812333173556 3 P51116 1
56
+ Agenet-like domain [IPR008395] 0.7361988101789307 1.1390648465328024 0.2546761083179336 1.0 0.8860812333173556 3 P51116 1
57
+ Fxr1, tudor domain [IPR041560] 0.7361988101789307 1.1390648465328024 0.2546761083179336 1.0 0.8860812333173556 3 P51116 1
58
+ Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7361988101789307 1.1390648465328024 0.2546761083179336 1.0 0.8860812333173556 3 P51116 1
59
+ Tim44-like domain [IPR007379] 0.8458927359131021 1.138113579216541 0.2550730586137502 1.0 0.8860812333173556 2 O43615 1
60
+ Lamin tail domain [IPR001322] 0.7320882852292045 1.122413813349467 0.2616865339483263 1.0 0.8913570617891382 3 P20700,Q03252 2
61
+ LEM-like domain [IPR013146] 0.8380855397148593 1.1065541102939935 0.2684867570920302 1.0 0.8936653060380984 2 P42167 1
62
+ Syntaxin, N-terminal domain [IPR006011] 0.8350305498981592 1.0942321435192544 0.2738531772588155 1.0 0.8936653060380984 2 O15400 1
63
+ CBS domain [IPR000644] 0.5639381978171216 1.0804817220995055 0.2799277217559639 1.0 0.8936653060380984 6 Q6P4Q7,Q8NE01,P51790,P54619 4
64
+ NOPS [IPR012975] 0.7215619694397103 1.0798469117736271 0.2802103570715788 1.0 0.8936653060380984 3 Q8WXF1,P23246 2
65
+ Marvel domain [IPR008253] 0.8302783435166242 1.0750976977701407 0.2823309901080919 1.0 0.8936653060380984 2 O43760 1
66
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.537517863665694 1.0537182609337905 0.2920119259132876 1.0 0.8936653060380984 11 P62942,Q02790,Q9NWM8,Q9Y680 4
67
+ Proteasome activator PA28, N-terminal domain [IPR003185] 0.7108658413226556 1.036724386117745 0.2998643236299574 1.0 0.8936653060380984 3 P61289 1
68
+ Proteasome activator PA28, C-terminal domain [IPR003186] 0.7108658413226556 1.036724386117745 0.2998643236299574 1.0 0.8936653060380984 3 P61289 1
69
+ Phox homology [IPR001683] 0.5479136194735592 1.0364976684478284 0.2999700265940621 1.0 0.8936653060380984 8 Q9Y5X3,O60749,Q96L92 3
70
+ Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.8194161575016943 1.0315268716586636 0.3022938135843329 1.0 0.8936653060380984 2 P23634 1
71
+ Peptidase M28 [IPR007484] 0.706621392190147 1.0196558992917382 0.3078916839301149 1.0 0.9007302924965872 3 Q969V3,Q7Z2K6 2
72
+ VPS13, repeated coiled region [IPR031642] 0.8129667345553222 1.0057766533702583 0.3145230203117961 1.0 0.9007302924965872 2 Q5THJ4 1
73
+ Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646] 0.8129667345553222 1.0057766533702583 0.3145230203117961 1.0 0.9007302924965872 2 Q5THJ4 1
74
+ Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543] 0.8129667345553222 1.0057766533702583 0.3145230203117961 1.0 0.9007302924965872 2 Q5THJ4 1
75
+ Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854] 0.8129667345553222 1.0057766533702583 0.3145230203117961 1.0 0.9007302924965872 2 Q5THJ4 1
76
+ Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645] 0.8129667345553222 1.0057766533702583 0.3145230203117961 1.0 0.9007302924965872 2 Q5THJ4 1
77
+ OCRE domain [IPR041591] 0.8058384249830288 0.977431279321897 0.3283556838411887 1.0 0.9071802116187132 2 P98175 1
78
+ Glycosyl transferase, family 1 [IPR001296] 0.8041412084181829 0.970701390585928 0.3316969991993503 1.0 0.9071802116187132 2 Q9BT22 1
79
+ ERAP1-like C-terminal domain [IPR024571] 0.5962473933405659 0.963870845276222 0.3351106823663816 1.0 0.9114304753397008 4 Q9UIQ6,Q9NZ08 2
80
+ Post-SET domain [IPR003616] 0.8014256619144531 0.9599494929159864 0.3370806351936881 1.0 0.9114304753397008 2 Q03164 1
81
+ YqgF/RNase H-like domain [IPR006641] 0.8004073319755596 0.9559226933398086 0.3391112928781483 1.0 0.9114304753397008 2 Q7KZ85 1
82
+ HHH domain 9 [IPR041692] 0.8004073319755596 0.9559226933398086 0.3391112928781483 1.0 0.9114304753397008 2 Q7KZ85 1
83
+ MD-2-related lipid-recognition domain [IPR003172] 0.797691785471814 0.94519867672169 0.3445574549155155 1.0 0.9168289374566696 2 P17900 1
84
+ Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.7970128988458931 0.9425209357136192 0.3459259976544333 1.0 0.917043371610167 2 O15460 1
85
+ Heavy metal-associated domain, copper ion-binding [IPR006122] 0.793618465716222 0.929152324038232 0.352810151114665 1.0 0.92047846229817 2 P35670 1
86
+ Heavy metal-associated domain, HMA [IPR006121] 0.793618465716222 0.929152324038232 0.352810151114665 1.0 0.92047846229817 2 P35670 1
87
+ FCP1 homology domain [IPR004274] 0.7929395790902914 0.9264826932453626 0.3541951871040094 1.0 0.92047846229817 2 Q3ZCQ8 1
88
+ SCP2 sterol-binding domain [IPR003033] 0.6825241703468254 0.923343959189902 0.3558279862493698 1.0 0.92047846229817 3 P51659 1
89
+ Threonine-tRNA ligase catalytic core domain [IPR033728] 0.790224032586547 0.9158181595696344 0.3597622772483575 1.0 0.92047846229817 2 Q9BW92 1
90
+ SUN coiled coil domain 2 [IPR040994] 0.7888662593346825 0.9104944357110796 0.3625618148774805 1.0 0.92047846229817 2 O94901 1
91
+ Ovarian carcinoma immunoreactive antigen domain [IPR009764] 0.7878479293957787 0.9065054509641588 0.3646683810326219 1.0 0.92047846229817 2 Q9NX40 1
92
+ Amino acid transporter, transmembrane domain [IPR013057] 0.7844534962661129 0.8932329110591024 0.3717324569590434 1.0 0.9344676707179228 2 Q96QD8 1
93
+ BRICHOS domain [IPR007084] 0.7837746096401784 0.8905829303788235 0.3731529600062984 1.0 0.9351670099749682 2 Q9NQX7 1
94
+ Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.7834351663272227 0.889258514963271 0.3738641613909252 1.0 0.9359942715352828 2 P51116 1
95
+ Peptidase M41 [IPR000642] 0.7803801765105214 0.8773562762982554 0.3802931541449308 1.0 0.9424823275276992 2 Q96TA2 1
96
+ Armadillo repeat-containing domain [IPR006911] 0.775288526816016 0.8575913435022616 0.3911181567008639 1.0 0.9463284059321708 2 Q8N2F6 1
97
+ Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.7674813306177862 0.827470193130997 0.4079706097196875 1.0 0.9514494443730156 2 O60506 1
98
+ Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.7640868974881161 0.8144478697922549 0.4153884247441097 1.0 0.9514494443730156 2 P51812 1
99
+ CARG-binding factor, N-terminal [IPR012956] 0.7634080108621839 0.8118489888252259 0.4168782879729975 1.0 0.9524214653597042 2 Q99729 1
100
+ Legume-like lectin [IPR005052] 0.7498302783435083 0.7602852939517103 0.4470840703845442 1.0 0.9737769404770732 2 P49257 1
101
+ Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.7376103190767108 0.7146106273700764 0.4748496760817589 1.0 0.9737769404770732 2 Q9NRF9 1
102
+ EH domain [IPR000261] 0.6288624787775937 0.7143774682725431 0.4749938007701684 1.0 0.9737769404770732 3 Q9H4M9,Q9H223 2
103
+ Potentiating neddylation domain [IPR005176] 0.623919667609026 0.6956658046256707 0.4866381452529094 1.0 0.9780550611629668 3 Q92564 1
104
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 0.4795930619823882 0.6669667633473778 0.5047933637024462 1.0 0.9892470230308252 6 Q9UIQ6,P09960,Q9NZ08 3
105
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.4795930619823882 0.6669667633473778 0.5047933637024462 1.0 0.9892470230308252 6 Q9UIQ6,P09960,Q9NZ08 3
106
+ Chromo domain subgroup [IPR017984] 0.6081494057724992 0.6367522245764717 0.5242862500677354 1.0 0.9922991488491008 3 P83916,Q13185 2
107
+ Chromo shadow domain [IPR008251] 0.6081494057724992 0.6367522245764717 0.5242862500677354 1.0 0.9922991488491008 3 P83916,Q13185 2
108
+ EF hand associated, type-2 [IPR013567] 0.715885947046839 0.6353854398527561 0.5251770618526244 1.0 0.9922991488491008 2 Q8IXI1 1
109
+ EF hand associated, type-1 [IPR013566] 0.715885947046839 0.6353854398527561 0.5251770618526244 1.0 0.9922991488491008 2 Q8IXI1 1
110
+ MIRO domain [IPR020860] 0.715885947046839 0.6353854398527561 0.5251770618526244 1.0 0.9922991488491008 2 Q8IXI1 1
111
+ ABC transporter-like, ATP-binding domain [IPR003439] 0.4661496177156982 0.6344882968249435 0.5257622020748345 1.0 0.9922991488491008 9 O75027,Q03519 2
112
+ L27 domain [IPR004172] 0.6061645779574706 0.6294289762938677 0.5290682527895738 1.0 0.9941787519902016 3 Q14168 1
113
+ L27 domain, C-terminal [IPR014775] 0.6061645779574706 0.6294289762938677 0.5290682527895738 1.0 0.9941787519902016 3 Q14168 1
114
+ TGS [IPR004095] 0.4683713558824226 0.6135587287012577 0.5395069630637102 1.0 0.9948920548071256 6 Q9BW92 1
115
+ Alpha-L-fucosidase, C-terminal [IPR031919] 0.7067209775967358 0.6028165678710131 0.5466307237584689 1.0 0.9948920548071256 2 Q9BTY2 1
116
+ Myb domain [IPR017930] 0.4581392359797223 0.5654631537929645 0.5717587793626393 1.0 0.9948920548071256 6 Q96KC8 1
117
+ RBM1CTR [IPR012604] 0.6934826883910329 0.5567762787565129 0.5776802929819493 1.0 0.9948920548071256 2 P38159 1
118
+ CRAL-TRIO lipid binding domain [IPR001251] 0.6924643584521297 0.5532867684903809 0.5800670599130526 1.0 0.9948920548071256 2 Q8NHP6 1
119
+ Major sperm protein (MSP) domain [IPR000535] 0.6870332654446615 0.5348076569694038 0.5927828677735865 1.0 0.9948920548071256 2 Q8NHP6 1
120
+ Sorting nexin Vps5-like, C-terminal [IPR015404] 0.4948936858925226 0.5346843393462234 0.5928681524960504 1.0 0.9948920548071256 4 Q9Y5X3 1
121
+ 4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.5718288886078647 0.5065629263516971 0.6124615267155376 1.0 0.9948920548071256 3 P21912 1
122
+ Class II aldolase/adducin N-terminal [IPR001303] 0.6771894093686321 0.501900949935502 0.615737197049155 1.0 0.9948920548071256 2 Q9UEY8 1
123
+ Man1/Src1, C-terminal [IPR018996] 0.6710794297352305 0.4818750425595559 0.6298947163770781 1.0 0.9948920548071256 2 Q9Y2U8 1
124
+ Dynamin GTPase effector [IPR003130] 0.6680244399185297 0.471981458597775 0.6369400230914388 1.0 0.9948920548071256 2 P50570 1
125
+ Dynamin stalk domain [IPR000375] 0.6680244399185297 0.471981458597775 0.6369400230914388 1.0 0.9948920548071256 2 P50570 1
126
+ GTPase effector domain [IPR020850] 0.6680244399185297 0.471981458597775 0.6369400230914388 1.0 0.9948920548071256 2 P50570 1
127
+ Zinc finger, RanBP2-type [IPR001876] 0.4277975857510645 0.4452749517795895 0.6561210671307727 1.0 0.9948920548071256 9 P35637,P49792,P98175,Q01844,P52756 5
128
+ RNA recognition motif domain, eukaryote [IPR003954] 0.4120993060356763 0.4364680657696951 0.6624971638891086 1.0 0.9948920548071256 14 Q14498,Q14011,Q9UHX1,Q01085,Q96I25,P38159 6
129
+ SUN domain [IPR012919] 0.543960789088873 0.4132223624642432 0.6794437055144935 1.0 0.9948920548071256 3 O94901 1
130
+ Rpn11/EIF3F, C-terminal [IPR024969] 0.4605978260869692 0.4039096304393496 0.6862791742670673 1.0 0.9948920548071256 4 O00303,Q7L5N1,P51665 3
131
+ RasGAP protein, C-terminal [IPR000593] 0.6364562118126211 0.3748067570895416 0.7078041885822945 1.0 0.9948920548071256 2 P46940 1
132
+ Mu homology domain [IPR028565] 0.4524456521739083 0.3745309944852822 0.7080093014962914 1.0 0.9948920548071256 4 P48444,Q9Y2T2,Q96CW1 3
133
+ EH domain-containing protein, N-terminal [IPR031692] 0.6337406653088871 0.3669093013995342 0.713686673102699 1.0 0.9948920548071256 2 Q9H223 1
134
+ Domain of unknown function DUF5600 [IPR040990] 0.6337406653088871 0.3669093013995342 0.713686673102699 1.0 0.9948920548071256 2 Q9H223 1
135
+ Pleckstrin homology domain, spectrin-type [IPR001605] 0.6320434487440533 0.3620128583786993 0.717342421635268 1.0 0.9948920548071256 2 O15020 1
136
+ Pleckstrin homology domain 9 [IPR041681] 0.6320434487440533 0.3620128583786993 0.717342421635268 1.0 0.9948920548071256 2 O15020 1
137
+ Cobalamin (vitamin B12)-binding domain [IPR006158] 0.6306856754921862 0.3581177625899028 0.7202551867900833 1.0 0.9948920548071256 2 Q99707 1
138
+ Heat shock protein Hsp90, N-terminal [IPR020575] 0.4432744565217462 0.3423839174420948 0.7320619899760517 1.0 0.9948920548071256 4 P07900,P14625,Q12931 3
139
+ MRH domain [IPR044865] 0.6221995926680173 0.3342255676557362 0.738209352048713 1.0 0.9948920548071256 2 P11717 1
140
+ Peptidase M16, N-terminal [IPR011765] 0.4057664916962945 0.3338447924094119 0.7384966811311668 1.0 0.9948920548071256 7 Q10713 1
141
+ Peptidase M16, C-terminal [IPR007863] 0.4057664916962945 0.3338447924094119 0.7384966811311668 1.0 0.9948920548071256 7 Q10713 1
142
+ 3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.6133740665308816 0.3102273947916463 0.756388039466751 1.0 0.9948920548071256 2 Q16836 1
143
+ 3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.6133740665308816 0.3102273947916463 0.756388039466751 1.0 0.9948920548071256 2 Q16836 1
144
+ Protein kinase, C-terminal [IPR017892] 0.4101001987097362 0.2825926549899688 0.7774891113992417 1.0 0.9948920548071256 5 P51812,P31751 2
145
+ Ras GTPase-activating domain [IPR001936] 0.4055548861657383 0.266289821260571 0.7900160116458899 1.0 0.9948920548071256 5 P46940,P21359,Q9UJF2 3
146
+ WW domain [IPR001202] 0.3730855058731933 0.2350283064455533 0.8141867631224926 1.0 0.9948920548071256 14 P46934 1
147
+ Far upstream element-binding protein, C-terminal [IPR015096] 0.5723014256619038 0.2107806247822671 0.8330584580716076 1.0 0.9948920548071256 2 Q96AE4 1
148
+ JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.3734693877551065 0.201723534317444 0.8401328630809695 1.0 0.9948920548071256 8 O15372,Q92905,O00303,O95630,O00487,Q7L5N1,P51665 7
149
+ Pumilio, RNA binding domain [IPR033712] 0.5553292600135659 0.1759250038000746 0.8603528615098175 1.0 0.9948920548071256 2 Q8TB72 1
150
+ Heat shock chaperonin-binding [IPR006636] 0.386209239130436 0.1679394961293518 0.866630877951128 1.0 0.9948920548071256 4 Q9UMX0,Q9NRR5,P54727 3
151
+ Ribosomal protein L10e/L16 [IPR016180] 0.5498981670061036 0.1655684609901087 0.8684965691535398 1.0 0.9948920548071256 2 Q9NX20 1
152
+ Cyclic nucleotide-binding domain [IPR000595] 0.3832659612479679 0.1602999279562308 0.872644815624148 1.0 0.9948920548071256 4 Q6P4Q7 1
153
+ Anticodon-binding [IPR004154] 0.3824389621960969 0.1581794959942711 0.8743153601645868 1.0 0.9948920548071256 4 Q9BW92 1
154
+ Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.4441426146010233 0.1464659254480388 0.8835535873513274 1.0 0.9948920548071256 3 Q8NEB9,Q9UBF8 2
155
+ ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100] 0.3768992414808112 0.1442739875566896 0.8852841183095923 1.0 0.9948920548071256 4 P06576 1
156
+ ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194] 0.3768992414808112 0.1442739875566896 0.8852841183095923 1.0 0.9948920548071256 4 P06576 1
157
+ eRF1 domain 2 [IPR005141] 0.5251188051595277 0.1232438774227732 0.9019139812279202 1.0 0.9948920548071256 2 P62495 1
158
+ eRF1 domain 1/Pelota-like [IPR005140] 0.5251188051595277 0.1232438774227732 0.9019139812279202 1.0 0.9948920548071256 2 P62495 1
159
+ eRF1 domain 3 [IPR005142] 0.5251188051595277 0.1232438774227732 0.9019139812279202 1.0 0.9948920548071256 2 P62495 1
160
+ Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297] 0.5183299389001919 0.1130481874270335 0.909992352003768 1.0 0.9948920548071256 2 Q13526 1
161
+ Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543] 0.5047522063815321 0.0944233899174112 0.9247728363420282 1.0 0.9948920548071256 2 Q13555 1
162
+ Ribosomal protein S7 domain [IPR023798] 0.4952477936184496 0.0827533174285427 0.9340476890416638 1.0 0.9948920548071256 2 Q9Y2R9 1
163
+ 26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.492532247114719 0.0796203657340258 0.9365391971248048 1.0 0.9948920548071256 2 Q15008 1
164
+ Adenylate kinase, active site lid domain [IPR007862] 0.4921928038017529 0.0792349443316991 0.9368457503981646 1.0 0.9948920548071256 2 Q9UIJ7 1
165
+ HECT domain [IPR000569] 0.3379556999893542 0.073310911415823 0.9415587090118492 1.0 0.9948920548071256 8 P46934 1
166
+ 60S ribosomal protein L10P, insertion domain [IPR040637] 0.4809911744738504 0.0672738365006855 0.9463637051389902 1.0 0.9948920548071256 2 P05388 1
167
+ ELMO domain [IPR006816] 0.4721656483367253 0.0588545120683833 0.953067989318762 1.0 0.9948920548071256 2 Q8IZ81 1
168
+ Survival motor neuron [IPR010304] 0.4684317718940931 0.0555485175775635 0.9557014781523084 1.0 0.9948920548071256 2 Q16637 1
169
+ Serine hydroxymethyltransferase-like domain [IPR039429] 0.4616429056347553 0.0499135108311923 0.960191310638088 1.0 0.9948920548071256 2 P34897 1
170
+ Rho GTPase-activating protein domain [IPR000198] 0.4599456890699246 0.0485786599686262 0.9612550767605132 1.0 0.9948920548071256 2 Q68EM7 1
171
+ Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.4365241004752169 0.0329629361294846 0.9737041442527152 1.0 0.9948920548071256 2 O15027 1
172
+ Exportin-1/Importin-beta-like [IPR013598] 0.3141983695652152 0.0243622294805767 0.9805636758851596 1.0 0.9948920548071256 4 Q9Y5L0,Q9HAV4,O14980 3
173
+ DNA mismatch repair protein MutS, clamp [IPR007861] 0.4131025118805143 0.0219356665309309 0.9824992738361488 1.0 0.995880403029955 2 P43246 1
174
+ PABP, RNA recognition motif 2 [IPR045305] 0.4097080787508408 0.0206614707189125 0.9835157043659106 1.0 0.9960589965615874 2 P11940 1
175
+ Importin-beta, N-terminal domain [IPR001494] 0.3232811266434509 0.0173322456502393 0.986171561154468 1.0 0.9963131856007296 14 Q8TEX9,Q92973,Q96P70,O15397,P55060 5
176
+ Thioredoxin domain [IPR013766] 0.2943730532933589 0.015956656998484 0.987268969992836 1.0 0.9970117558809232 24 Q9H3N1,Q9Y320,Q9H1E5,Q96JJ7 4
177
+ Arfaptin homology (AH) domain [IPR010504] 0.3852681602172454 0.0134797664355054 0.9892450281826192 1.0 0.9973669085453666 2 P53365 1
178
+ DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.3053668478260824 0.0129527811760506 0.989665464859626 1.0 0.9973813630263608 4 O60306,Q9HCE1,P51530 3
179
+ STAG [IPR013721] 0.3632043448743956 0.009411731357253 0.9924906357238952 1.0 0.9994083646321796 2 Q8WVM7 1
180
+ Stromalin conservative domain [IPR020839] 0.3632043448743956 0.009411731357253 0.9924906357238952 1.0 0.9994083646321796 2 Q8WVM7 1
181
+ GINS subunit, domain A [IPR021151] 0.3365025466893084 0.0068462251259696 0.9945375453438434 1.0 1.0 3 Q9Y248,Q9BRT9 2
182
+ cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.3214528173794984 0.0056684483459302 0.9954772568013616 1.0 1.0 2 P10644 1
interpro_domain/selections.json ADDED
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interpro_family/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Mitochondrial carrier protein [IPR002067]", "1": "P-type ATPase [IPR001757]"}
interpro_family/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: 4696bdcb55b6d3423181803af82f8d6d783d4edbd3653d1204528228b3252f38
  • Pointer size: 131 Bytes
  • Size of remote file: 181 kB
interpro_family/advanced/plot_1.png ADDED

Git LFS Details

  • SHA256: 0b2eafb127df0df332666602a0329d6547bc65138c07b113ce33c3ea606caa53
  • Pointer size: 131 Bytes
  • Size of remote file: 176 kB
interpro_family/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Mitochondrial carrier protein [IPR002067]", "1": "P-type ATPase [IPR001757]", "2": "Short-chain dehydrogenase/reductase SDR [IPR002347]"}
interpro_family/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 5b6863d7cbaf2c9c4e199a546ccff33fa86aefae1b4b934e6530d04a7fb798a4
  • Pointer size: 131 Bytes
  • Size of remote file: 139 kB