diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..bd97e69ef026ea08e3f3be34c52f8c824e215e2d --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84b041f16cd13dfe475038569b9c22b904dc75cb2c9be5c4090b20043a687ffd +size 66973 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..209d65d4e6c8cc5ca4dee15fe9c28cf4f6a8bad4 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 56, + "title": "Average number of proteins per term", + "value": 2.517857142857143 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f19b4a9463ebf08a96bff45bef341719dabe0bdc --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..074f404fc20486a9fa5b5fa8abf65fa38695cbc5 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.6768532618148109 1.266411571110783 0.2053657703819462 0.9999974333476328 0.6159670371092135 4 P21281 1 +Tyrosine-protein kinase, active site [IPR008266] 0.6437316019702691 1.2265594244520246 0.2199882275390048 0.9999990928798488 0.6159670371092135 5 Q05397 1 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.3821688758135551 0.2239765144443452 0.8227755777743384 1.0 0.9639343263360156 5 P61088,P61086 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..336d42b23f288aa89ee93058756d3b4ad90fbe06 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK3", "MAPKAPK2", "MARK2", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "YES1"], "leading_proteins": ["ATP6V1B2", "PTK2", "UBE2K", "UBE2N"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/advanced/plot_0.png b/interpro_binding_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..50f94dc3edee524a0caff06d66658185be0ebe19 --- /dev/null +++ b/interpro_binding_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2d152c555741e80373a9adfc5684d886a48fac5feaaf4eb010ea64e039ca3bff +size 193302 diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..73edc5cd7c298be496f07c5e6c0d6e1c40212645 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f3022264143adf7fa3291ad19cf14441053c5e144e6ec3ac53dabe79ef83bb21 +size 133430 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..360d6931e6c21f8aa4332f008d808f56dcc8be3f --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d589513d196859cc8ec07f37163c4459faf81823aef390f6eaa1ce64bd71cc16 +size 67123 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..876fb597eeccc201539acf578ba9c3e3c5b178ed --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Beta tubulin, autoregulation binding site [IPR013838] 2 5 2.0886500996036728 0.0367392318215795 3.5533980582524274 5.54126213592233 0.5823511994709325 0.3808337519133083 1.5578062452886454 0.9632803779920796 1.1906256051626651 0.3058955364405814 1.0 1.0 0.0190953097419897 0.0078003581692789 +EF-Hand 1, calcium-binding site [IPR018247] 8 36 2.080869098993809 0.0374458892580209 10.019417475728156 36.70631067961165 0.9532938980945532 0.3894555773109194 3.76037227687173 3.057484685571999 1.1082350706804749 0.3408841825650379 0.0571768496395965 0.0001193437580118 0.0001239561832085 0.0145017950635795 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a6a33c67697ceb1c9b9b8201b0ef694b177e5691 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 29, + "title": "Average number of proteins per term", + "value": 4.724137931034483 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9d3226f247d47177c88d80913d4cb1b11fda1e18 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d8cb3c58baf0c4bae191d72d8ea60a7ac785185c --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Beta tubulin, autoregulation binding site [IPR013838] 0.8478959576286953 2.0886500996036728 0.0367392318215795 0.6622679263720737 0.2171861576965214 5 P04350,Q13509 2 +EF-Hand 1, calcium-binding site [IPR018247] 0.5625312438278048 2.080869098993809 0.0374458892580209 0.6693797581932253 0.2171861576965214 36 Q15293,P80303,Q9Y680,Q03001,Q96D71,O43852,Q14257,Q9NWM8 8 +IQ motif, EF-hand binding site [IPR000048] 0.3655560078148655 0.2154479834317667 0.8294180628992658 1.0 0.9293171038550646 10 Q7Z406,Q12965 2 +Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.4564921821889974 0.0380395860750782 0.9696561197313645 1.0 0.9696561197313645 2 O15270 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3d1b073837d54ccd550edb4103eb6658ae28956d --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK2", "CDK4", "CDK5", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "HPCAL4", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALU", "DST", "FKBP14", "FKBP7", "MYH14", "MYO1E", "NUCB2", "RCN1", "RCN2", "REPS1", "SPTLC2", "TUBB3", "TUBB4A"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..23cf4e794d27a35dad54bb237740d6ea74a76d35 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Ubiquitin specific protease, conserved site [IPR018200]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4ac274787623a980f9f21f45665bb548d4ffb84a --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a2fc36a89f4cef4bbf6581ca0b990717fb83a13822f54a4f9712dc5a7d09c410 +size 150571 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7b64b055f7c6556451f4ffbb388e020b8812cc01 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a685a071edb4a076e70fe14e2b6e8bf22fce067f78ab60079e29db254e7431b2 +size 72850 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b43a03f2d5b2eafc061276ca748b82fbe13727a2 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Tubulin, conserved site [IPR017975] 2 6 2.0837649840842003 0.0371815498916539 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 1.0 1.0 0.0703212183088513 0.0547354250806853 +Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 2 7 2.032651040455806 0.0420877909608381 2.813106796116505 7.288834951456311 -0.5861883336862886 0.343247888518411 1.6359205295141483 0.5883757483977968 1.1482455180262974 0.2604113174624136 0.0012601973854463 0.0049445172385496 0.0020533662966424 0.0142438301551866 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9e66fbbe95be49545e996eb897293bfe850f8e7c --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 266, + "title": "Average number of proteins per term", + "value": 2.601503759398496 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..56c3156b660af049dfebf1c6a8e4f15ff88a3685 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b32cdc6a87005274bece735bb393cda4fca37583 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,30 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tubulin, conserved site [IPR017975] 0.7826484314400508 2.0837649840842003 0.0371815498916539 0.9999580423229096 0.5603837243124605 6 P04350,Q13509 2 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.8681159883452286 2.0472377529396293 0.0406347463107645 0.9999838660746164 0.5603837243124605 4 O75874,P48735 2 +Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.7694572769681502 2.032651040455806 0.0420877909608381 0.9999892195104616 0.5603837243124605 7 P30837,O94788 2 +Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.7516193874837721 1.9523787737940703 0.0508932512240236 0.9999990757140176 0.5603837243124605 7 O94788 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.9109146548792968 1.8373999190232135 0.0661508787786799 0.9999999875947352 0.5603837243124605 3 P04439,P55899 2 +Thioredoxin, conserved site [IPR017937] 0.7079746957469231 1.7902104972039192 0.0734200781956946 0.999999998448158 0.5603837243124605 11 O43396,Q8IXB1,O95881,Q9H1E5 4 +Mini-chromosome maintenance, conserved site [IPR018525] 0.6766274316759404 1.6051885542876427 0.1084523155696706 0.9999999999999452 0.6071192135066216 6 Q14566 1 +Intermediate filament protein, conserved site [IPR018039] 0.663825150252697 1.5485215545566662 0.1214967762953254 0.9999999999999988 0.631403335740457 7 Q16352,P08670 2 +Annexin repeat, conserved site [IPR018252] 0.6325654317404608 1.4008759057112858 0.1612511849723037 1.0 0.6808383365497269 6 P09525 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.579026490968136 1.1489606720535088 0.2505721977584918 1.0 0.7750256349274283 8 P28070,P49721,P28074,P28072 4 +Ras GTPase-activating protein, conserved site [IPR023152] 0.644897959183666 1.1339379283730704 0.2568205859509449 1.0 0.7762985893517199 4 Q13576,P21359,Q9UJF2 3 +Syntaxin/epimorphin, conserved site [IPR006012] 0.5359109608662675 0.9494700943492118 0.3423815750478391 1.0 0.8509618793482965 6 O15400 1 +Bromodomain, conserved site [IPR018359] 0.5163694381589082 0.8503821752392225 0.3951126428777129 1.0 0.8710586085587104 9 O60885,Q8WWQ0,P25440 3 +Ubiquitin specific protease, conserved site [IPR018200] 0.5086727184745982 0.8212548880206758 0.411501097874182 1.0 0.8806718182169455 13 Q96K76,Q93009,Q96RU2,Q9Y4E8,O94966,Q86UV5 6 +Haem oxygenase conserved site [IPR018207] 0.8167912984364164 0.6844427174278496 0.4936956494100495 1.0 0.9104475908958268 2 P30519 1 +Zinc finger, RING-type, conserved site [IPR017907] 0.4590869709563887 0.5819230001762992 0.5606185473273604 1.0 0.9104475908958268 12 Q9Y508,Q5VTR2,O75150,P19474 4 +Tetraspanin, conserved site [IPR018503] 0.7749830047586405 0.5548761607741955 0.5789793688361762 1.0 0.9104475908958268 2 O43657 1 +Guanylate kinase, conserved site [IPR020590] 0.4959183673469237 0.5457710782523366 0.5852233062090251 1.0 0.9104475908958268 4 O14936,Q14168,Q00013 3 +Chromo domain, conserved site [IPR023779] 0.4615399149566019 0.4274031433048695 0.6690857183430468 1.0 0.9532932769020036 4 P83916 1 +Cullin, conserved site [IPR016157] 0.375978223885675 0.2078028321013188 0.8353829211892656 1.0 0.9825672467849456 5 Q13618,Q13616,Q13620,Q93034 4 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.440666439986408 0.2008938603246885 0.8407815685998914 1.0 0.9825672467849456 3 P26583,O15347 2 +Heat shock protein Hsp90, conserved site [IPR019805] 0.4219653179190805 0.1652420917970556 0.8687534361493536 1.0 0.9825672467849456 3 P07900,P14625 2 +Vinculin, conserved site [IPR000633] 0.5978925900747816 0.1515853208422929 0.879514011874571 1.0 0.9825672467849456 2 P35221 1 +4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.5910944935418151 0.1420630663382039 0.8870301910259024 1.0 0.9825672467849456 2 P21912 1 +Heavy-metal-associated, conserved site [IPR017969] 0.589734874235221 0.1402147845357756 0.888490290931397 1.0 0.9825672467849456 2 Q04656 1 +Clathrin adaptor complex, small chain [IPR000804] 0.3239666715622738 0.050703717708038 0.9595616141592485 1.0 1.0 3 P61923 1 +Ribosomal protein S2, conserved site [IPR018130] 0.402447314751875 0.0273367781190042 0.9781911231241496 1.0 1.0 2 Q9Y399 1 +GHMP kinase, ATP-binding, conserved site [IPR006203] 0.3956492182189078 0.026614373930262 0.978767308582532 1.0 1.0 2 Q03426 1 +Actinin-type actin-binding domain, conserved site [IPR001589] 0.2892360333684851 0.0025023564787074 0.998003410483718 1.0 1.0 14 Q01082,Q03001 2 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8644b78a8da25cf969cd765ce74ba213c412ed90 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARHGEF7", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", 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sha256:4352365ff104200342828202032b7c1c603a8ff1fb430e1cdfb4d65e176e7919 +size 134433 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..74c377db9471713f80b60ef492dce4ed824a2abe --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c1491175fbeeaa7f97923c97ece8138de5b8d867675e24868c955b11902840d5 +size 146887 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1db2fcf1d89b17ca5f474bf59572482fb3c29606 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 3 6 2.584510527278764 0.0097517327477087 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0015075035399645 0.0058956460302812 0.0001472775053537 0.0020333503076747 +EF-hand domain [IPR002048] 9 43 2.315931702963612 0.0205619980119591 12.385922330097088 43.512135922330096 1.0171858714399242 0.3947118087831401 4.608360476919044 4.087317384177653 1.201458704248258 0.3652478399429377 0.086158736226278 0.0004337843976712 0.0007348691657886 0.0238902452884441 +Tubulin/FtsZ, GTPase domain [IPR003008] 2 6 2.0837649840842003 0.0371815498916539 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 1.0 1.0 0.0703212183088513 0.0547354250806853 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 2 6 2.0837649840842003 0.0371815498916539 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 1.0 1.0 0.0635022977163126 0.0472723399635447 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a264ebf3cd44e3a78b947f0d00cc430e94345ad6 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 2456, + "title": "Average number of proteins per term", + "value": 2.128257328990228 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..41ebd191d522ab0a75d6c15749998b89c7a5995a --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..14095ac2109bfc23ff10e5e599bc51369fce571e --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,248 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.8994336803183094 2.584510527278764 0.0097517327477087 0.9999999999647232 0.5366622929175038 6 Q8WUJ1,O00264,Q9UMX5 3 +EF-hand domain [IPR002048] 0.4877557211740539 2.315931702963612 0.0205619980119591 1.0 0.5366622929175038 43 Q15293,P80303,Q96AY3,Q9Y680,Q03001,Q96D71,O43852,Q14257,Q9NWM8 9 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.9281775428983474 2.2825732984512417 0.0224555152964909 1.0 0.5366622929175038 4 P13674,Q32P28 2 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.9281775428983474 2.2825732984512417 0.0224555152964909 1.0 0.5366622929175038 4 P13674,Q32P28 2 +SET domain [IPR001214] 0.8866804292073569 2.120583634988873 0.0339568565043968 1.0 0.5366622929175038 4 Q9H7B4 1 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.7826484314400508 2.0837649840842003 0.0371815498916539 1.0 0.5366622929175038 6 P04350,Q13509 2 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.7826484314400508 2.0837649840842003 0.0371815498916539 1.0 0.5366622929175038 6 P04350,Q13509 2 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.8681159883452286 2.0472377529396293 0.0406347463107645 1.0 0.5366622929175038 4 O75874,P48735 2 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.9506970418225112 1.9870566773423464 0.0469161163912774 1.0 0.5366622929175038 3 P13674,Q32P28 2 +MHC class I-like antigen recognition-like [IPR011161] 0.818707482993203 1.849518161771563 0.0643830277731551 1.0 0.5366622929175038 4 P01889,P04439,P55899 3 +Immunoglobulin-like domain [IPR007110] 0.7002769686792378 1.741407225230719 0.0816122226190463 1.0 0.5373716320439083 10 Q13308,P10586,Q08722,P55899,P04439 5 +Immunoglobulin C1-set [IPR003597] 0.7625111407461862 1.734449026941902 0.0828384425515922 1.0 0.5425365730845614 5 P01889,P04439,P55899 3 +Zinc finger, RanBP2-type [IPR001876] 0.6937796188207104 1.7009763822779411 0.0889474221775676 1.0 0.5484726819214312 9 P52756,Q92804,Q01844,P35637 4 +Aldehyde dehydrogenase domain [IPR015590] 0.6901322531430072 1.6929913239393228 0.0904571186667948 1.0 0.5484726819214312 10 P30837,O94788 2 +RNA recognition motif domain [IPR000504] 0.4970241012339994 1.662264625124535 0.0964597273428917 1.0 0.5484726819214312 110 Q9Y5S9,Q01844,Q8IUH3,Q96I25,P52756,Q8TBF4,Q99729,Q92804,Q07955,P31483,O43719,Q01085,Q96E39,Q13242,O43390,P98175,O14979,Q08170,P62995,P51991,P84103,Q8IXT5,Q9GZT3,Q76FK4,P19338,Q13243,Q8WXF1,P38159,Q9UN86,P98179,Q12849,P35637,Q86U42,P31942,Q96T58,P23246,Q8N684,Q8WVV9,P23588,Q96PK6,Q13247,Q9BWF3,Q15056,P11940,Q14011,P22626,O60506,Q9P2K5,Q9Y4C8 49 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8648376533775312 1.6619966986832917 0.0965134364163997 1.0 0.5484726819214312 3 Q16352 1 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.6817357293873945 1.628705753139509 0.1033753242744286 1.0 0.5556661185558089 6 P55786 1 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.6817357293873945 1.628705753139509 0.1033753242744286 1.0 0.5556661185558089 6 P55786 1 +DNA2/NAM7 helicase, helicase domain [IPR041677] 0.854983952558509 1.624240943644252 0.1043243957036812 1.0 0.5581057421846566 3 P51530 1 +LEM domain [IPR003887] 0.6777379835622169 1.610304613530563 0.1073313725640998 1.0 0.5682101342372771 6 P50402,Q8NC56,Q9Y2U8 3 +MCM OB domain [IPR033762] 0.6766274316759404 1.6051885542876427 0.1084523155696706 1.0 0.5682101342372771 6 Q14566 1 +MCM N-terminal domain [IPR027925] 0.6766274316759404 1.6051885542876427 0.1084523155696706 1.0 0.5682101342372771 6 Q14566 1 +MCM, AAA-lid domain [IPR041562] 0.6766274316759404 1.6051885542876427 0.1084523155696706 1.0 0.5682101342372771 6 Q14566 1 +MCM domain [IPR001208] 0.6766274316759404 1.6051885542876427 0.1084523155696706 1.0 0.5682101342372771 6 Q14566 1 +Intermediate filament, rod domain [IPR039008] 0.663825150252697 1.5485215545566662 0.1214967762953254 1.0 0.5816442909190905 7 Q16352,P08670 2 +MIF4G-like, type 3 [IPR003890] 0.660427607412895 1.5326379365686404 0.1253650888161712 1.0 0.5932498229913614 7 O43432,Q9H074 2 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.7298707682912791 1.4861864764583623 0.1372298035918189 1.0 0.6114129428319003 4 O60306,P51530 2 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.8184291057463512 1.4835948464136426 0.1379164374303227 1.0 0.6114129428319003 3 P01889,P04439 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.8184291057463512 1.4835948464136426 0.1379164374303227 1.0 0.6114129428319003 3 P01889,P04439 2 +ERAP1-like C-terminal domain [IPR024571] 0.7234255144054279 1.4595341038074936 0.1444181611701043 1.0 0.6163844904572254 4 P55786 1 +Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.6439270499166078 1.4552873658160643 0.1455897228452098 1.0 0.6163844904572254 7 Q8N4Q0 1 +Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.8067423752776902 1.438482304217775 0.1502972548387873 1.0 0.6235305031825366 3 Q9Y4E8 1 +JmjC domain [IPR003347] 0.803655810218831 1.4265595157444368 0.1537069004748243 1.0 0.6246479821148951 3 Q9NWT6 1 +SWAP/Surp [IPR000061] 0.6302459928312976 1.3900604377640704 0.1645105254980254 1.0 0.6413299216240484 6 Q12872,Q8IWZ8,Q15459 3 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.6221827785181886 1.3721479251813775 0.1700173926932129 1.0 0.6473840565186526 11 Q9NWM8,Q96AY3,Q9Y680 3 +BAG domain [IPR003103] 0.7014067077318726 1.3683091246803514 0.1712153358248884 1.0 0.6499302392363617 4 Q9UL15,O95429 2 +Zinc finger, CCHC-type [IPR001878] 0.6083488705436076 1.2875858157827411 0.1978901794754719 1.0 0.688867403169469 7 Q9BWF3,Q8TBF4,Q15637,Q9NUD5 4 +ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194] 0.6768532618148109 1.266411571110783 0.2053657703819462 1.0 0.6962822110154651 4 P21281 1 +ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100] 0.6768532618148109 1.266411571110783 0.2053657703819462 1.0 0.6962822110154651 4 P21281 1 +W2 domain [IPR003307] 0.5985753168037045 1.241382451571803 0.2144644986663069 1.0 0.7041775517706547 7 P55010 1 +Ras GTPase-activating domain [IPR001936] 0.6451173868662965 1.232530741914833 0.2177508902791243 1.0 0.7058251055661036 5 Q9UJF2,P21359,Q14C86,Q13576 4 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7504250255015429 1.2208105618911151 0.2221577538867514 1.0 0.7075205721756898 3 P51114,Q06787 2 +Fxr1, tudor domain [IPR041560] 0.7504250255015429 1.2208105618911151 0.2221577538867514 1.0 0.7075205721756898 3 P51114,Q06787 2 +Agenet-like domain [IPR008395] 0.7504250255015429 1.2208105618911151 0.2221577538867514 1.0 0.7075205721756898 3 P51114,Q06787 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7504250255015429 1.2208105618911151 0.2221577538867514 1.0 0.7075205721756898 3 P51114,Q06787 2 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.5937912666114845 1.2195112783976705 0.2226501978031672 1.0 0.7075205721756898 8 Q13308,Q9UHY1,Q05397 3 +Ras-associating (RA) domain [IPR000159] 0.7500850051003152 1.219497911819264 0.2226552679529554 1.0 0.7075205721756898 3 Q9Y4G8,Q96L92 2 +Cyclic nucleotide-binding domain [IPR000595] 0.6638547050364713 1.2124747576334052 0.2253306994623027 1.0 0.7087584619319709 4 Q6P4Q7,Q9Y4G8 2 +Zinc finger, MYND-type [IPR002893] 0.9694085656016276 1.2093318185959607 0.2265353913194381 1.0 0.7087584619319709 2 Q9H7B4 1 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.5884744536945954 1.1947207139819918 0.2321961666193801 1.0 0.7164243532879367 6 O95140,O00429,O60313 3 +Dynamin, N-terminal [IPR045063] 0.5884744536945954 1.1947207139819918 0.2321961666193801 1.0 0.7164243532879367 6 O95140,O00429,O60313 3 +Zinc finger, CHHC-type [IPR012996] 0.7402244134648062 1.1814568330789117 0.2374212921192251 1.0 0.7243561409252385 3 P55795,P52597 2 +SUN domain [IPR012919] 0.7398406100740381 1.179977294199059 0.2380092457241873 1.0 0.7252490167476479 3 Q9UH99 1 +Immunoglobulin subtype 2 [IPR003598] 0.655140366442258 1.176346421609942 0.2394564725349397 1.0 0.7278528422596684 4 P10586 1 +Immunoglobulin subtype [IPR003599] 0.655140366442258 1.176346421609942 0.2394564725349397 1.0 0.7278528422596684 4 P10586 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.958871515975525 1.1716208423003325 0.2413493163720095 1.0 0.7280369968629739 2 P98179 1 +NOPS [IPR012975] 0.7375042502550254 1.170972844906886 0.2416096924864814 1.0 0.7280369968629739 3 P23246,Q8WXF1 2 +UBX domain [IPR001012] 0.6523809523809588 1.164914353157622 0.2440536629642775 1.0 0.7298035769319617 4 Q96CS3,Q9UNZ2,O94888 3 +Bromodomain [IPR001487] 0.5732325993283758 1.1452349082201545 0.2521118615058377 1.0 0.7371270617361161 13 Q03164 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.9503738953093096 1.1412967239490035 0.2537464649855292 1.0 0.7399104184229117 2 P13674 1 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.7270467893290082 1.1307186577802326 0.2581735258091231 1.0 0.7463884689455754 3 O75431 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.7270467893290082 1.1307186577802326 0.2581735258091231 1.0 0.7463884689455754 3 O75431 1 +Ataxin-2, C-terminal [IPR009818] 0.6421768707482987 1.1226843374185267 0.2615715823093767 1.0 0.7488929324119981 4 Q9BPZ3,Q8WWM7,Q9H074 3 +Immunoglobulin I-set [IPR013098] 0.7227621300777232 1.114252521053117 0.265170869382012 1.0 0.753053772356319 3 P10586 1 +MIT domain [IPR007330] 0.7211832709962718 1.1081893625047912 0.2677800438961326 1.0 0.7554602412232364 3 O75351,Q8N0X7 2 +Peripheral subunit-binding domain [IPR004167] 0.720537003415064 1.1057082833032954 0.2688528035932063 1.0 0.7554602412232364 3 O00330 1 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.9401767505098536 1.1050265364138137 0.2691480908266823 1.0 0.7554602412232364 2 Q9NRG0 1 +Band 7 domain [IPR001107] 0.5691869353312204 1.1024473790197593 0.270267223320475 1.0 0.7562889936537951 7 P27105 1 +Mu homology domain [IPR028565] 0.6321789870225427 1.081395505594848 0.2795212200290766 1.0 0.7633221603216395 4 P48444 1 +Major facilitator superfamily domain [IPR020846] 0.6310814008270151 1.0768691792293004 0.2815387140049921 1.0 0.7633221603216395 4 Q9H2V7,P53985 2 +Guanylate kinase-like domain [IPR008144] 0.5617913240739075 1.0699009239011028 0.2846639071965504 1.0 0.7667851396669695 6 Q00013 1 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.5617913240739075 1.0699009239011028 0.2846639071965504 1.0 0.7667851396669695 6 Q00013 1 +BAT2, N-terminal [IPR009738] 0.711092942767471 1.0695039786873957 0.2848426370114532 1.0 0.7667851396669695 3 Q5JSZ5 1 +Rhodanese-like domain [IPR001763] 0.6921299674598473 0.9971650454844484 0.3186844045672747 1.0 0.8002953963366327 3 Q99956 1 +Lamin tail domain [IPR001322] 0.6905814348861038 0.9912827431669088 0.3215475370255551 1.0 0.8017469552637192 3 Q03252,P02545 2 +Dynamin, GTPase domain [IPR001401] 0.6889725186922379 0.9851755484222054 0.3245378490297415 1.0 0.8043036904309233 3 O00429 1 +Fatty acid hydroxylase [IPR006694] 0.905166553365058 0.9817390707140492 0.3262284118717713 1.0 0.8052431955347441 2 Q15800 1 +VHS domain [IPR002014] 0.6843697722171831 0.9677304865043944 0.3331789882940521 1.0 0.8067222402525855 3 O14964 1 +Transcription factor IIS, N-terminal [IPR017923] 0.682205071221273 0.9595399829886496 0.3372867874102696 1.0 0.8067222402525855 3 Q14241 1 +Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.682205071221273 0.9595399829886496 0.3372867874102696 1.0 0.8067222402525855 3 Q14241 1 +RNA recognition motif domain, eukaryote [IPR003954] 0.5295949046868641 0.9325830334051448 0.3510352968474937 1.0 0.82030703050185 14 P38159,Q96I25,Q8TBF4,Q96E39,Q01085,P31483,P19338,Q14011,Q9Y4C8 9 +Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.5239583250406226 0.9040345459839888 0.3659770835329767 1.0 0.8321058609262691 14 Q96K76,Q93009,Q96RU2,Q53GS9,Q9Y4E8,O94966,Q86UV5 7 +Ubiquitin specific protease domain [IPR028889] 0.5239583250406226 0.9040345459839888 0.3659770835329767 1.0 0.8321058609262691 14 Q96K76,Q93009,Q96RU2,Q53GS9,Q9Y4E8,O94966,Q86UV5 7 +DnaJ domain [IPR001623] 0.5202259489048804 0.8936558544690778 0.3715060519205666 1.0 0.8332592360885038 15 Q8IXB1,O75937,O14976,Q9UGP8,Q9NVH1 5 +K Homology domain, type 1 [IPR004088] 0.4862076982070744 0.8671286223938602 0.3858715395377712 1.0 0.8393331669671308 24 Q8N9N2,Q96AE4,P51114,Q15637,O75179,Q06787,P61978 7 +UAS [IPR006577] 0.6521591295477804 0.8469602821237243 0.3970172600408277 1.0 0.8518658937116582 3 Q96CS3,O94888 2 +RBM1CTR [IPR012604] 0.8636981645139296 0.8391414962208478 0.401389912507617 1.0 0.8587226699640309 2 P38159 1 +AMP-binding enzyme, C-terminal domain [IPR025110] 0.5666346448732437 0.8150196476354918 0.4150610637158025 1.0 0.8720187959675031 4 Q4G176 1 +Chromo shadow domain [IPR008251] 0.6415545635318725 0.8078174618002513 0.4191956713778326 1.0 0.876954487993149 3 P83916 1 +Chromo domain subgroup [IPR017984] 0.6415545635318725 0.8078174618002513 0.4191956713778326 1.0 0.876954487993149 3 P83916 1 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.6408585025634155 0.805260894381305 0.4206691431058433 1.0 0.877793895894606 3 Q9Y4E8 1 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.8490822569680448 0.7900646409956342 0.4294900184611079 1.0 0.8870295529020007 2 P20020 1 +Zinc finger, GATA-type [IPR000679] 0.5584877050805365 0.7827400626000999 0.4337797710567295 1.0 0.888712465538538 4 Q8WXI9 1 +Tyrosine-specific protein phosphatases domain [IPR000387] 0.499197160549566 0.7760290164157454 0.4377318534711139 1.0 0.8906954698633436 7 Q99956 1 +Pleckstrin homology domain 9 [IPR041681] 0.8402447314751872 0.7607498090401167 0.4468065181324383 1.0 0.9022199595790368 2 Q01082 1 +Pleckstrin homology domain, spectrin-type [IPR001605] 0.8402447314751872 0.7607498090401167 0.4468065181324383 1.0 0.9022199595790368 2 Q01082 1 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.5275523867954955 0.7341770392385529 0.4628408453997197 1.0 0.9084255515205476 5 Q14141 1 +CLASP N-terminal domain [IPR024395] 0.6120367222033438 0.7009936096317186 0.4833070032597977 1.0 0.9167220696966836 3 Q7Z460,Q14008 2 +Myosin tail [IPR002928] 0.6116967018021269 0.699784120904726 0.4840621328254242 1.0 0.9167220696966836 3 Q7Z406,P35579 2 +WW domain [IPR001202] 0.4814143883290562 0.6883891509540598 0.4912077539579949 1.0 0.9167220696966836 13 Q13526,Q6ZWJ1,O00213,O75400,O95817,P46939 6 +OCRE domain [IPR041591] 0.8144119646498988 0.6768334534233048 0.4985116301255816 1.0 0.9221164694541928 2 P52756 1 +SUN coiled coil domain 2 [IPR040994] 0.8079537729435529 0.6563123199496013 0.5116231922615708 1.0 0.9266903866816192 2 Q9UH99 1 +Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.8055744391570173 0.6488020636160625 0.5164663234493578 1.0 0.9319921310739332 2 Q08170 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.4679996005541807 0.6423622655600757 0.5206379943694373 1.0 0.9350697422249672 6 O15400 1 +Man1/Src1, C-terminal [IPR018996] 0.8031951053704904 0.6413195326806853 0.5213151012031467 1.0 0.9352446227574348 2 Q9Y2U8 1 +Beta-adaptin appendage, C-terminal subdomain [IPR015151] 0.5923155389323445 0.631772639198539 0.527535454718949 1.0 0.9380741439109082 3 O00203,Q10567 2 +Rab-GTPase-TBC domain [IPR000195] 0.5192780340701368 0.6315629108025058 0.5276725285781292 1.0 0.9380741439109082 4 Q8TC07,Q66K14 2 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.5185016972274388 0.6286532972838538 0.5295760595813259 1.0 0.9380741439109082 4 Q05397 1 +Ubiquitin-like domain [IPR000626] 0.4673883435297601 0.6216673603781083 0.5341606180641136 1.0 0.9380741439109082 13 O14920,Q86UV5,Q15459,P46379 4 +Disulphide isomerase [IPR005788] 0.4933650901667346 0.5976079820072455 0.5501015369939906 1.0 0.9481712289524034 5 P07237,P30101,P13667,Q8NBS9 4 +TOG domain [IPR034085] 0.4586335695140252 0.5950911650088473 0.5517825340072255 1.0 0.9481712289524034 7 Q86Y56,Q7Z460,Q14008,O75122,O00410 5 +SH3 domain [IPR001452] 0.3988711039565449 0.592304134845959 0.5536469475682766 1.0 0.9481712289524034 32 O60504,Q92783,Q12965,Q9UNF0,Q9UKS6,Q03001,Q14247,Q9Y5K6,Q13813,P41240,P62993,Q14847,Q9UQB8,Q5JRA6,Q00013,Q14155 16 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.7841604350781798 0.582513218387075 0.560221040546917 1.0 0.9481712289524034 2 O43390 1 +K Homology domain [IPR004087] 0.4390310411422813 0.5752681963173113 0.5651099271529345 1.0 0.9481712289524034 23 Q96AE4,P51114,Q15637,O75179,Q06787,P61978 6 +Death domain [IPR000488] 0.5742944576674659 0.5703744322427086 0.5684237670430381 1.0 0.9481712289524034 3 Q96FV9,Q12955 2 +F-BAR domain [IPR031160] 0.7675050985723746 0.5327281197099255 0.5942217978526161 1.0 0.960412525893046 2 Q9UKS6 1 +FCH domain [IPR001060] 0.7675050985723746 0.5327281197099255 0.5942217978526161 1.0 0.960412525893046 2 Q9UKS6 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.5575446846806056 0.5151621480678524 0.6064397171559968 1.0 0.9657278452494656 3 Q10472 1 +Zinc finger, RING-type [IPR001841] 0.4269410244275113 0.4947478762236614 0.6207781018432053 1.0 0.9674291386120624 22 Q9Y508,Q86TM6,O75150,Q5VTR2,Q9H270,Q96T88,P19474,O15344,Q14527 9 +NET domain [IPR027353] 0.7515295717199211 0.4866027243730014 0.6265398925254364 1.0 0.9696151703425636 2 O60885 1 +Brdt, bromodomain, repeat I [IPR043508] 0.7515295717199211 0.4866027243730014 0.6265398925254364 1.0 0.9696151703425636 2 O60885 1 +Brdt, bromodomain, repeat II [IPR043509] 0.7515295717199211 0.4866027243730014 0.6265398925254364 1.0 0.9696151703425636 2 O60885 1 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.7501699524133134 0.4827556664771522 0.629269232705185 1.0 0.9720032927823486 2 P51114 1 +SMCs flexible hinge [IPR010935] 0.4626511637847912 0.4815338458428342 0.6301371306782482 1.0 0.9727321137308468 5 Q9UQE7 1 +Zinc finger, C3HC4 RING-type [IPR018957] 0.5381797509443874 0.4538929888936571 0.6499058500627886 1.0 0.9771661325382284 3 Q5VTR2 1 +Ricin B, lectin domain [IPR000772] 0.4681088036759974 0.4491839313637339 0.6532989780616651 1.0 0.9771661325382284 4 Q10472 1 +Myb domain [IPR017930] 0.419335334327187 0.4392870452498035 0.6604535598480616 1.0 0.9779891945217092 6 Q8TAQ2,Q13330,Q96KC8 3 +Chromo/chromo shadow domain [IPR000953] 0.4187870856630446 0.4223299583632594 0.6727841941456105 1.0 0.9782287504471184 8 P83916,Q8TAQ2,P45973 3 +Peptidase M16, C-terminal [IPR007863] 0.4151249223491747 0.4147918492396867 0.6782942868657094 1.0 0.9782287504471184 7 O43847 1 +Peptidase M16, N-terminal [IPR011765] 0.4151249223491747 0.4147918492396867 0.6782942868657094 1.0 0.9782287504471184 7 O43847 1 +Chromo domain [IPR023780] 0.4120535448605701 0.4108552281186869 0.6811786936165376 1.0 0.9802778045660748 6 P83916,P45973 2 +Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253] 0.7209381373215533 0.4032784192721352 0.6867434158299521 1.0 0.9812147669790394 2 O75351 1 +CSN8/PSMD8/EIF3K [IPR033464] 0.5196646630694414 0.3982365087671421 0.6904558566545151 1.0 0.9812147669790394 3 Q99627 1 +Phox homology [IPR001683] 0.4080011507286245 0.3799642319159438 0.7039719662584174 1.0 0.9812147669790394 8 O60493,Q96L92 2 +SWIB/MDM2 domain [IPR003121] 0.7100611828687733 0.3753927806399235 0.7073683732107552 1.0 0.9812147669790394 2 P41214 1 +GINS subunit, domain A [IPR021151] 0.5108631420862998 0.3728858326305885 0.709233416739294 1.0 0.9812147669790394 3 Q9BRT9 1 +Extracellular Endonuclease, subunit A [IPR020821] 0.7056424201223521 0.3643433462297086 0.7156016353353007 1.0 0.9812147669790394 2 P22413 1 +DNA/RNA non-specific endonuclease [IPR001604] 0.7056424201223521 0.3643433462297086 0.7156016353353007 1.0 0.9812147669790394 2 P22413 1 +Coatomer subunit gamma, C-terminal [IPR032154] 0.693745751189671 0.3354258579203666 0.7373038648329437 1.0 0.9812147669790394 2 Q9Y678 1 +Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.693745751189671 0.3354258579203666 0.7373038648329437 1.0 0.9812147669790394 2 Q9Y678 1 +CTLH, C-terminal LisH motif [IPR006595] 0.4964297857871599 0.3329860675710498 0.7391448000773091 1.0 0.9812147669790394 3 Q9H7D7,Q96S59 2 +L27 domain, C-terminal [IPR014775] 0.4957497449847055 0.33115958932566 0.7405239426730215 1.0 0.9812147669790394 3 O14936,Q14168 2 +L27 domain [IPR004172] 0.4957497449847055 0.33115958932566 0.7405239426730215 1.0 0.9812147669790394 3 O14936,Q14168 2 +CNNM, transmembrane domain [IPR002550] 0.6832087015635443 0.31085884551288 0.7559079319740849 1.0 0.9812147669790394 2 Q6P4Q7 1 +Ion transporter-like, CBS domain [IPR044751] 0.6832087015635443 0.31085884551288 0.7559079319740849 1.0 0.9812147669790394 2 Q6P4Q7 1 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.4071700835245262 0.2951309310009515 0.7678938619934608 1.0 0.9812147669790394 5 P20020 1 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.4071700835245262 0.2951309310009515 0.7678938619934608 1.0 0.9812147669790394 5 P20020 1 +PDZ domain [IPR001478] 0.3851407993133247 0.2913388716522285 0.7707921609012001 1.0 0.9812147669790394 22 Q9UDY2,Q6ZWJ1,Q9HD26,Q53GG5,Q09666,O14641,Q9Y4G8,Q96RT1,Q96L92,Q00013 10 +Ubiquitin-associated domain [IPR015940] 0.3908070888987643 0.2890802701551234 0.7725199514802106 1.0 0.9812147669790394 14 Q14157,Q9Y5A7 2 +Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.3828080329177477 0.2801915888963425 0.7793305194195623 1.0 0.9812147669790394 9 P11310 1 +Nuclear transport factor 2, eukaryote [IPR018222] 0.4125006852794557 0.2800521152293225 0.7794375217203766 1.0 0.9812147669790394 4 Q9UN86 1 +Nuclear transport factor 2 domain [IPR002075] 0.4125006852794557 0.2800521152293225 0.7794375217203766 1.0 0.9812147669790394 4 Q9UN86 1 +Cullin homology domain [IPR016158] 0.372021783526214 0.2668251539425449 0.7896037861258762 1.0 0.9812147669790394 6 Q93034,Q13618,Q13620,Q13617,Q13616 5 +CARG-binding factor, N-terminal [IPR012956] 0.6600951733514584 0.2605804065816988 0.7944161010687734 1.0 0.9812147669790394 2 Q99729 1 +Cullin, N-terminal [IPR001373] 0.3721484508001341 0.2585939126705978 0.7959485805174591 1.0 0.9812147669790394 7 Q86Y37,Q93034,Q13618,Q13620,Q13617,Q13616 6 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.4644678680720955 0.2527259370733642 0.8004800034779329 1.0 0.9812147669790394 3 P21912,P61221 2 +Far upstream element-binding protein, C-terminal [IPR015096] 0.6549966009517224 0.2501806898173602 0.8024476178081206 1.0 0.9812147669790394 2 Q96AE4 1 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.3989795918367309 0.2448327156594415 0.806585961245379 1.0 0.9812147669790394 4 P07900,P14625,P08238 3 +R3H domain [IPR001374] 0.4549472968378143 0.2311446157535849 0.8172024550975898 1.0 0.9812147669790394 3 Q9H6S0,O95453 2 +SWIRM domain [IPR007526] 0.3933809297309592 0.231009578053051 0.817307361058339 1.0 0.9812147669790394 4 Q8NB78 1 +SCP2 sterol-binding domain [IPR003033] 0.4546072764365941 0.2303945308247856 0.817785210626623 1.0 0.9812147669790394 3 Q6YN16,P51659 2 +RasGAP protein, C-terminal [IPR000593] 0.6444595513256342 0.2295018797820592 0.8184788597607435 1.0 0.9812147669790394 2 Q13576 1 +ROCK, Rho binding domain [IPR015008] 0.6420802175390878 0.2249858730470443 0.821990264224054 1.0 0.9812147669790394 2 O75116 1 +Tim10-like [IPR004217] 0.3783154726062996 0.2138389078234978 0.8306726825980708 1.0 0.9812147669790394 5 Q9Y5J9,Q9Y5L4 2 +Zasp-like motif [IPR006643] 0.632902787219584 0.2081019309630564 0.8351493794753904 1.0 0.9812147669790394 2 Q53GG5 1 +Cullin protein, neddylation domain [IPR019559] 0.375978223885675 0.2078028321013188 0.8353829211892656 1.0 0.9812147669790394 5 Q13618,Q13616,Q13620,Q93034 4 +STAT transcription factor, DNA-binding [IPR013801] 0.6288239292997924 0.2008722539794677 0.8407984636160704 1.0 0.9812147669790394 2 P42224 1 +STAT transcription factor, all-alpha domain [IPR013800] 0.6288239292997924 0.2008722539794677 0.8407984636160704 1.0 0.9812147669790394 2 P42224 1 +STAT transcription factor, protein interaction [IPR013799] 0.6288239292997924 0.2008722539794677 0.8407984636160704 1.0 0.9812147669790394 2 P42224 1 +G-patch domain [IPR000467] 0.3627545656146133 0.1955812768399134 0.8449379161659969 1.0 0.9812147669790394 12 Q96I25,P52756,P98175,Q8IWZ8 4 +Copine, C2B domain [IPR037768] 0.4372662359741558 0.1940743137240243 0.8461176939069033 1.0 0.9812147669790394 3 O75131,Q86YQ8 2 +Copine, C-terminal [IPR010734] 0.4372662359741558 0.1940743137240243 0.8461176939069033 1.0 0.9812147669790394 3 O75131,Q86YQ8 2 +PWWP domain [IPR000313] 0.346433567461913 0.1791174637671588 0.8578454696555253 1.0 0.9812147669790394 7 Q7Z4V5 1 +Longin domain [IPR010908] 0.4240054403264288 0.1689098441966928 0.865867555910435 1.0 0.9812147669790394 3 P51809,O75396 2 +v-SNARE, coiled-coil homology domain [IPR042855] 0.4240054403264288 0.1689098441966928 0.865867555910435 1.0 0.9812147669790394 3 P51809,O75396 2 +Legume-like lectin [IPR005052] 0.6087695445275385 0.1678002305760797 0.8667404410979984 1.0 0.9812147669790394 2 Q12907 1 +EF-hand, Ca insensitive [IPR014837] 0.4233253995239893 0.1676812011202756 0.866834086109795 1.0 0.9812147669790394 3 Q13813,P12814 2 +Thioredoxin domain [IPR013766] 0.3513870097366262 0.1633402570142467 0.8702505389902817 1.0 0.9812147669790394 24 O43396,Q8IXB1,O95881,Q9H3N1,Q9BS26,Q9H1E5,Q96JJ7 7 +DNA mismatch repair protein MutS, core [IPR007696] 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 0.9812147669790394 3 P43246,P52701 2 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 0.9812147669790394 3 P43246,P52701 2 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 0.9812147669790394 3 P43246,P52701 2 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 0.9812147669790394 3 P43246,P52701 2 +HR1 rho-binding domain [IPR011072] 0.3585034013605508 0.155482315943674 0.8764410942329803 1.0 0.9812147669790394 4 Q16513,Q13464,O75116 3 +Cobalamin (vitamin B12)-binding domain [IPR006158] 0.5924541128484001 0.1439300324029906 0.8855557201656925 1.0 0.9812147669790394 2 Q99707 1 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.3520408163265335 0.1435509112342636 0.8858551062044799 1.0 0.9812147669790394 4 Q9UNH7,Q9Y5X3,O60749 3 +Elongation factor EFG, domain V-like [IPR000640] 0.3477373256209661 0.141852920296526 0.8871961823189058 1.0 0.9812147669790394 5 Q96RP9,Q7Z2Z2,Q8N442,Q15029 4 +Heavy metal-associated domain, HMA [IPR006121] 0.589734874235221 0.1402147845357756 0.888490290931397 1.0 0.9812147669790394 2 Q04656 1 +Heavy metal-associated domain, copper ion-binding [IPR006122] 0.589734874235221 0.1402147845357756 0.888490290931397 1.0 0.9812147669790394 2 Q04656 1 +HECT domain [IPR000569] 0.3309499489274664 0.1371752586515459 0.8908922667572352 1.0 0.9812147669790394 7 Q9ULT8,Q05086,Q7Z6Z7,Q96PU5,Q15386,Q14669 6 +Ribosomal protein S7 domain [IPR023798] 0.5822569680489533 0.1303816776752757 0.8962644619421329 1.0 0.9812147669790394 2 P46782 1 +OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365] 0.3405920381081954 0.1272724768577297 0.8987247434183936 1.0 0.9812147669790394 5 Q6PI48,O43776,P27694,P14868 4 +DDT domain [IPR018501] 0.3981638898334013 0.1264858311199813 0.899347364094387 1.0 0.9812147669790394 3 Q9NRL2,Q9UIG0 2 +WHIM2 domain [IPR028941] 0.3981638898334013 0.1264858311199813 0.899347364094387 1.0 0.9812147669790394 3 Q9NRL2,Q9UIG0 2 +AP complex, mu/sigma subunit [IPR022775] 0.3231635560563956 0.1263789389437065 0.8994319727607734 1.0 0.9812147669790394 6 Q92572,P61923 2 +Matrin/U1-C, C2H2-type zinc finger [IPR000690] 0.3418069820127463 0.1259933867699315 0.8997371594520176 1.0 0.9812147669790394 4 Q12874 1 +Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364] 0.3404761904761936 0.1238303264062656 0.9014496196065388 1.0 0.9812147669790394 4 Q6PI48,O43776,P14868 3 +Double-stranded RNA-binding domain [IPR014720] 0.3422532353218218 0.120277969240056 0.9042629554031468 1.0 0.9812147669790394 15 Q96SI9 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.3927235634138094 0.1186662534818264 0.9055397734063462 1.0 0.9812147669790394 3 P61289,Q9UL46 2 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.3927235634138094 0.1186662534818264 0.9055397734063462 1.0 0.9812147669790394 3 P61289,Q9UL46 2 +Peptidase M41 [IPR000642] 0.5723997280761391 0.1182707049319668 0.9058531685349092 1.0 0.9812147669790394 2 Q9Y4W6 1 +YTH domain [IPR007275] 0.5720598232494974 0.1178701501422977 0.906170545073588 1.0 0.9812147669790394 2 Q9H6S0 1 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.3920435226113675 0.1177157172875766 0.9062929127756674 1.0 0.9812147669790394 3 Q13464,O75116 2 +Myosin head, motor domain [IPR001609] 0.3246329017000218 0.1134155022340467 0.90970115000459 1.0 0.9812147669790394 8 Q12965 1 +Importin-beta, N-terminal domain [IPR001494] 0.3334470989761064 0.0992221498926759 0.9209618885652476 1.0 0.9864293058509588 14 P55060,Q14974,Q96P70,O00410,Q9UIA9,Q8TEX9,Q9HAV4,Q9UI26,O14980,O15397,O95373,O43592,Q92973 13 +FERM domain [IPR000299] 0.3172580354272795 0.0961020492093732 0.9234395238085328 1.0 0.9873606749994588 8 Q05397 1 +Nucleotidyl transferase domain [IPR005835] 0.3699421965317912 0.0900173791392484 0.928273404339516 1.0 0.9893042903822852 3 Q96IJ6,Q9NR50 2 +ZU5 domain [IPR000906] 0.5414683888511297 0.0863165679299543 0.9312147683264228 1.0 0.9893042903822852 2 Q12955 1 +PTB/PI domain [IPR006020] 0.3653208283036231 0.084989975137684 0.9322693605538904 1.0 0.9893042903822852 3 O00213 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.3098146523417641 0.0797719984717695 0.936418595313444 1.0 0.9893042903822852 8 P20020 1 +SLIDE domain [IPR015195] 0.5261726716519459 0.0737017245043578 0.9412477265670832 1.0 0.990141122994045 2 O60264 1 +ISWI, HAND domain [IPR015194] 0.5261726716519459 0.0737017245043578 0.9412477265670832 1.0 0.990141122994045 2 O60264 1 +Methyl-CpG DNA binding [IPR001739] 0.5234534330387577 0.0716649216056077 0.942868572858088 1.0 0.9913036022857296 2 O95983 1 +B-box, C-terminal [IPR003649] 0.3352601156069299 0.0582757321150821 0.953528997622789 1.0 0.9976524842875796 3 Q13263,O15344 2 +SANT domain [IPR017884] 0.2975052403362523 0.0552988844097427 0.9559003509202189 1.0 0.9982550512129272 8 Q8TAQ2,Q13330 2 +START domain [IPR002913] 0.496600951733524 0.0546250855013773 0.9564371532519744 1.0 0.9982550512129272 2 Q14849 1 +Glycosyltransferase 2-like [IPR001173] 0.2802460314250374 0.0533567324504425 0.957447678577574 1.0 0.9982550512129272 4 Q10472 1 +Vps4 oligomerisation, C-terminal [IPR015415] 0.3202711273479812 0.0484894301898429 0.961326188020814 1.0 0.9982550512129272 3 O75351 1 +Thioredoxin-like fold [IPR012336] 0.4799456152277453 0.0465917932874993 0.9628385729365404 1.0 0.9982550512129272 2 Q8NBF2 1 +FERM central domain [IPR019748] 0.2926430262505616 0.0392634080055247 0.9686803802882415 1.0 0.9982550512129272 9 Q05397 1 +Band 4.1 domain [IPR019749] 0.2926430262505616 0.0392634080055247 0.9686803802882415 1.0 0.9982550512129272 9 Q05397 1 +CCAAT-binding factor [IPR005612] 0.2893573614416841 0.0344197934631389 0.9725423999214028 1.0 0.9982550512129272 3 Q03701,Q9BVI4 2 +Domain of unknown function DUF4749 [IPR031847] 0.2890173410404555 0.0343043020442057 0.9726344943551049 1.0 0.9982550512129272 3 Q53GG5,O00151 2 +SANT/Myb domain [IPR001005] 0.2893240075506926 0.0335791961273637 0.9732127119968952 1.0 0.9982550512129272 9 Q8TAQ2,Q13330,Q96KC8 3 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059] 0.4384772263766211 0.0332923997277907 0.9734414145403892 1.0 0.9982550512129272 2 P07814 1 +Zinc finger, FYVE-related [IPR017455] 0.2440737043112158 0.0329170189368626 0.9737407610010338 1.0 0.9982550512129272 4 O14964 1 +FYVE zinc finger [IPR000306] 0.2440737043112158 0.0329170189368626 0.9737407610010338 1.0 0.9982550512129272 4 O14964 1 +Nop domain [IPR002687] 0.2845970758245443 0.0328705217625332 0.9737778403132114 1.0 0.9982550512129272 3 Q8WWY3,O00567 2 +NOSIC [IPR012976] 0.2845970758245443 0.0328705217625332 0.9737778403132114 1.0 0.9982550512129272 3 Q8WWY3,O00567 2 +Domain of unknown function DUF5600 [IPR040990] 0.4313392250170044 0.0317772361727939 0.9746497003692748 1.0 0.9982550512129272 2 Q9H4M9 1 +EH domain-containing protein, N-terminal [IPR031692] 0.4313392250170044 0.0317772361727939 0.9746497003692748 1.0 0.9982550512129272 2 Q9H4M9 1 +Proteasome component (PCI) domain [IPR000717] 0.3118216523649327 0.0305948438351818 0.9755926542499558 1.0 0.9982550512129272 18 Q7L2H7,Q99627,Q96PV6,Q9BT78,Q9UBQ5,O00231,Q9Y262 7 +Pleckstrin homology domain [IPR001849] 0.3132158629478752 0.0290354726667977 0.9768362994157164 1.0 0.9982550512129272 23 O15020,O75116,Q9BZF1,Q01082,Q96TA1,Q9UJF2,P31751 7 +Extended synaptotagmin, C2A domain [IPR037733] 0.4109449354180893 0.028395040075289 0.9773470800544132 1.0 0.9982550512129272 2 A0FGR8 1 +Synaptotagmin, SMP domain [IPR039010] 0.4109449354180893 0.028395040075289 0.9773470800544132 1.0 0.9982550512129272 2 A0FGR8 1 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.4109449354180893 0.028395040075289 0.9773470800544132 1.0 0.9982550512129272 2 A0FGR8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.4109449354180893 0.028395040075289 0.9773470800544132 1.0 0.9982550512129272 2 A0FGR8 1 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.4109449354180893 0.028395040075289 0.9773470800544132 1.0 0.9982550512129272 2 A0FGR8 1 +WSTF/Acf1/Cbp146 [IPR013136] 0.4082256968049017 0.028036385799273 0.9776331308734014 1.0 0.9982550512129272 2 Q9NRL2 1 +Glycogen synthase kinase 3, catalytic domain [IPR039192] 0.3990482664853879 0.0269626217342541 0.9784895467199152 1.0 0.9982550512129272 2 P49840 1 +GHMP kinase N-terminal domain [IPR006204] 0.3956492182189078 0.026614373930262 0.978767308582532 1.0 0.9982550512129272 2 Q03426 1 +GHMP kinase, C-terminal domain [IPR013750] 0.3956492182189078 0.026614373930262 0.978767308582532 1.0 0.9982550512129272 2 Q03426 1 +Domain of unknown function DUF1747 [IPR013719] 0.3745751189666937 0.0249523611101138 0.9800929620904972 1.0 0.9982550512129272 2 Q9Y5B9 1 +GUCT [IPR012562] 0.3718558803535059 0.0247911082389504 0.9802215834776912 1.0 0.9982550512129272 2 Q9BQ39 1 +BRK domain [IPR006576] 0.3555404486743773 0.0240218283098815 0.9808351972562795 1.0 0.9982550512129272 2 P51532 1 +Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.2378847426546398 0.0238131287447086 0.9810016677956804 1.0 0.9982550512129272 3 Q8NEB9 1 +ABC-transporter extension domain [IPR032781] 0.3358259687287613 0.0234423064960822 0.9812974585640288 1.0 0.9982550512129272 2 Q9NUQ8 1 +mRNA splicing factor Cwf21 domain [IPR013170] 0.3348062542488156 0.0234202166515812 0.9813150788722562 1.0 0.9982550512129272 2 O15042 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1d44a8054c10190ff04251f67d205ab796846ca1 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA C-terminal domain [IPR032423]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ASCH domain [IPR007374]", "ATF7-interacting protein , protein binding domain [IPR031870]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCAS3 domain [IPR022175]", "BCL10, CARD domain [IPR042143]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Basic-leucine zipper domain [IPR004827]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bms1/Tsr1-type G domain [IPR030387]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CCZ1/INTU, second Longin domain [IPR043988]", "CCZ1/INTU/HPS4, third Longin domain [IPR043989]", "CCZ1/INTU/HSP4, first Longin domain [IPR043987]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COQ9 [IPR013718]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Clusterin, C-terminal [IPR016015]", "Clusterin, N-terminal [IPR016014]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coactivator CBP, pKID [IPR003102]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cupin-like domain 8 [IPR041667]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DTX3L, RING-HC finger [IPR042843]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deltex, C-terminal [IPR039396]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3498 [IPR021887]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4187 [IPR025239]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF775 [IPR008493]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase AMFR, Ube2g2-binding region [IPR040675]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF114, RING finger, HC subclass [IPR042716]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAK1/PYK2, FERM domain C-lobe [IPR041784]", "FAM3C (ILEI) domain [IPR039475]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focal adhesion kinase, N-terminal [IPR041390]", "Focal adhesion kinase, targeting (FAT) domain [IPR005189]", "Follistatin-like, N-terminal [IPR003645]", "Follistatin/Osteonectin EGF domain [IPR015369]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gasdermin, PUB domain [IPR041263]", "Gasdermin, pore forming domain [IPR040460]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HBS1-like protein, N-terminal [IPR015033]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Int12, PHD finger [IPR039054]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KOW [IPR005824]", "Kazal domain [IPR002350]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM7, LYR domain [IPR045298]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIR motif [IPR016093]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTMR14, PH-GRAM domain [IPR039803]", "MTMR6, PH-GRAM domain [IPR035998]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "MgsA AAA+ ATPase C-terminal [IPR021886]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein FAM210A/B-like domain [IPR009688]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Proto-oncogene c-Rel, RHD, N-terminal subdomain [IPR042845]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "Quinolinate phosphoribosyl transferase, C-terminal [IPR002638]", "Quinolinate phosphoribosyl transferase, N-terminal [IPR022412]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Radical SAM [IPR007197]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SF3A3 domain [IPR031774]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm4 [IPR034101]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "SoHo domain [IPR003127]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Somatomedin B domain [IPR001212]", "Somatomedin B, chordata [IPR020436]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of fused C-terminal [IPR024314]", "Suppressor of fused-like domain [IPR020941]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Unconventional myosin-Ie/If, SH3 domain [IPR035507]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting protein 11, C-terminal [IPR024763]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 13D, UBA domain [IPR041969]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Vinexin, SH3 domain 1 [IPR035609]", "Vinexin, SH3 domain 2 [IPR035608]", "Vinexin, SH3 domain 3 [IPR035607]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WRNIP1, ubiquitin-binding domain [IPR040539]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZN598/Hel2, RING finger [IPR041888]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger C2HC RNF-type [IPR034734]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger CCCH domain [IPR041686]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARMC10", "ARMCX3", "ARMT1", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATF7IP", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7A", "ATP7B", "ATXN10", "ATXN2L", "AUP1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCL10", "BCS1L", "BIRC6", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPTF", "BRD1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C11orf58", "C1orf35", "C2CD2", "CACUL1", "CACYBP", "CAD", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CASK", "CASP3", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCZ1B", "CD2AP", "CD47", "CDC23", "CDC37", "CDC42", "CDC5L", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2AIP", "CEBPZ", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CERS4", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLU", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT3", "CNPY2", "COA3", "COG4", "COIL", "COLEC12", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "CORO7", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCK", "DCP1A", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "EMC1", "EMC7", "EMD", "EML4", "ENDOD1", "ENO1", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM129B", "FAM208A", "FAM210A", "FAM3C", "FAM49B", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXK1", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH11", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPCAL4", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISOC1", "ISYNA1", "ITGB1", "ITM2C", "ITPK1", "IVD", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRPPRC", "LRRC47", "LSM12", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LYAR", "LYPLA1", "LYPLA2", "LYRM7", "MACF1", "MAD2L1", "MAGED2", "MAN2B1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "METAP2", "METTL13", "MFN2", "MGME1", "MIA3", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCBP1", "NCEH1", "NCL", "NCLN", "NCSTN", "NDUFA10", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFE", "NEMF", "NENF", "NES", "NF1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCIAD2", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXNAD1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIH1D1", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLPBP", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR3A", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP4C", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PUM1", "PUM2", "PUM3", "PUS1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "QARS", "QKI", "QPRT", "QRICH1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RAD21", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDX", "RECQL", "REL", "REPS1", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOK1", "RIOK2", "RIPK1", "RMND1", "RNASEH2A", "RNF114", "RNF20", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRP12", "RSF1", "RSL24D1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL2", "SDAD1", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A4", "SLC2A8", "SLC38A1", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SMYD3", "SNAP23", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYVN1", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDP2", "TDRKH", "TECR", "TEDC1", "TELO2", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFRC", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM10", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT1L", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSR1", "TST", "TTC4", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4B", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN7", "UCHL5", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UQCRC1", "UQCRC2", "UQCRFS1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTRN", "VAMP7", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VKORC1L1", "VPS11", "VPS13A", "VPS13D", "VPS16", "VPS29", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WRNIP1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YES1", "YIPF4", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF598", "ZNF638", "ZNF830", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["ABCE1", "ABCF3", "ACADM", "ACSF3", "ACTN1", "AFG3L2", "AHNAK", "AKT2", "ALDH1A2", "ALDH1B1", "ANK3", "ANKRD17", "AP1B1", "AP3B1", "AP3S1", "APBB1", "AQR", "ARCN1", "ARHGEF7", "ASCC1", "ATP2B1", "ATP6V1B2", "ATP7A", "ATXN2L", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BRD4", "CACUL1", "CALU", "CASK", "CBX1", "CBX5", "CD2AP", "CD47", "CEBPZ", "CHRAC1", "CIRBP", "CKAP5", "CLASP1", "CLASP2", "CNNM4", "COPG1", "COPS4", "COPS8", "COPZ1", "CPNE3", "CPNE8", "CPSF7", "CSE1L", "CSK", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5D2", "DARS", "DARS2", "DDX50", "DNA2", "DNAAF5", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC8", "DNM1L", "DST", "DUSP9", "DVL2", "EFL1", "EFTUD2", "EHD1", "EIF2B3", "EIF2D", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4G3", "EIF4H", "EIF5", "ELOA", "EMD", "ENPP1", "EPRS", "ERBIN", "ERP44", "ESYT2", "EWSR1", "FAF2", "FAM129B", "FCGRT", "FKBP10", "FKBP14", "FKBP7", "FMR1", "FUBP1", "FUS", "FXR1", "G3BP2", "GAK", "GALNT1", "GAPVD1", "GATAD2B", "GFM1", "GINS4", "GMPPA", "GOPC", "GRB2", "GRSF1", "GSK3A", "GUF1", "HDGFL2", "HECTD1", "HGS", "HIF1AN", "HLA-A", "HLA-B", "HLTF", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPDL", "HNRNPF", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPLL", "HNRNPR", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HTATSF1", "HUWE1", "IDH1", "IDH2", "IKBKB", "INA", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP2", "KDM1B", "KMT2A", "KPNB1", "LASP1", "LEMD2", "LEMD3", "LENG8", "LMAN2", "LMNA", "LMNB2", "MBD3", "MCM6", "MFN2", "MIA3", "MID1", "MPP1", "MPP2", "MSH2", "MSH6", "MSMO1", "MTA1", "MTR", "MTX2", "MVK", "MYEF2", "MYH14", "MYH9", "MYO1E", "NARS", "NCL", "NEDD4L", "NENF", "NF1", "NHLRC2", "NOC4L", "NOL8", "NOP56", "NPEPPS", "NRBP1", "NRDC", "NSFL1C", "NUB1", "NUCB2", "OPA1", "OSBPL8", "P3H1", "P4HA1", "P4HB", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAIP1", "PAIP2", "PARN", "PDHX", "PDIA3", "PDIA4", "PDLIM1", "PDLIM3", "PGRMC1", "PIK3C3", "PIN1", "PKN2", "PRPF31", "PRPF40A", "PRRC2B", "PSMD11", "PSME2", "PSME3", "PSPC1", "PTK2", "PTK7", "PTPRF", "RANBP9", "RAPGEF2", "RASAL2", "RBM10", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM3", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RCN1", "RCN2", "REPS1", "RNF114", "RNF20", "RNF40", "ROCK1", "ROCK2", "RPA1", "RPS5", "SDHB", "SEC22B", "SEC63", "SEPT6", "SF1", "SF3A1", "SF3A3", "SFPQ", "SFSWAP", "SLC16A1", "SLIRP", "SMARCA4", "SMARCA5", "SMARCC2", "SMC3", "SMYD3", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SORBS3", "SPART", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SRSF1", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF9", "STAM", "STARD3", "STAT1", "STOM", "STRBP", "STX7", "STXBP4", "SUGP1", "SUN2", "SUPT16H", "SYNCRIP", "SYVN1", "TAF15", "TBC1D15", "TBC1D9B", "THOC1", "TIA1", "TIAL1", "TIMM13", "TIMM8B", "TJP2", "TMX1", "TMX3", "TMX4", "TNPO1", "TRA2B", "TRIM21", "TRIM28", "TRIP12", "TUBB3", "TUBB4A", "TXNDC12", "TXNDC5", "TXNL1", "U2SURP", "UBAP2L", "UBE3A", "UBE3C", "UBXN7", "UHRF1", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP7", "UTRN", "VAMP7", "VIM", "VPS11", "VPS4B", "WDR26", "XPO1", "XPO5", "XPO7", "XPOT", "YTHDC2", "ZADH2", "ZCCHC3", "ZCRB1"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1c4ac603dc505e0442fd9d3a294e8ed2289bc4c1 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:861159c1d69bb9621dce3d641d7b78b34f894b2a8257a7f7d64af13a4be229c8 +size 166984 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..90ed8aa40d25b3e71ee9753af85483c8adfb01e2 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Beta tubulin [IPR002453] 2 5 2.0886500996036728 0.0367392318215795 3.5533980582524274 5.54126213592233 0.5823511994709325 0.3808337519133083 1.5578062452886454 0.9632803779920796 1.1906256051626651 0.3058955364405814 1.0 1.0 0.0190953097419897 0.0078003581692789 +Tubulin [IPR000217] 2 6 2.0837649840842003 0.0371815498916539 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 1.0 1.0 0.0703212183088513 0.0547354250806853 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7d40597bf7ba1795f5e392d974dd16b75596672d --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 2300, + "title": "Average number of proteins per term", + "value": 1.2782608695652173 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..42b9cf362570e62969b3650bf30abe7ce889ce91 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1b568c48720cd7b6373d2ca77d3904d585458d02 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,89 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Beta tubulin [IPR002453] 0.8478959576286953 2.0886500996036728 0.0367392318215795 1.0 0.4374144784354016 5 P04350,Q13509 2 +Tubulin [IPR000217] 0.7826484314400508 2.0837649840842003 0.0371815498916539 1.0 0.4374144784354016 6 P04350,Q13509 2 +TAF15/EWS/TLS family [IPR034870] 0.9119347160829688 1.841259229759771 0.0655835792885568 1.0 0.4395043767368204 3 Q92804,P35637 2 +Proteasome B-type subunit [IPR023333] 0.6975830124539089 1.7054056403671796 0.0881187971238 1.0 0.4488751844326261 7 P28070,P49721,P28074,P28072 4 +Nucleosome assembly protein (NAP) [IPR002164] 0.8667120027201676 1.669169688292641 0.0950837554882702 1.0 0.4518133120109063 3 Q01105,Q99733 2 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.6817357293873945 1.628705753139509 0.1033753242744286 1.0 0.4600966896031853 6 P55786 1 +Mini-chromosome maintenance protein [IPR031327] 0.6766274316759404 1.6051885542876427 0.1084523155696706 1.0 0.4660883210303727 6 Q14566 1 +Small GTPase, Ras-type [IPR020849] 0.7462346854475572 1.553717845901058 0.1202517343317 1.0 0.4824832999460108 4 Q9UL25 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.8333900034002097 1.5412548031870463 0.1232547841956579 1.0 0.4853592075882342 3 P28074,P28072 2 +DNA2/NAM7-like helicase [IPR045055] 0.7298707682912791 1.4861864764583623 0.1372298035918189 1.0 0.5068962555438625 4 O60306,P51530 2 +Aminopeptidase N-type [IPR034016] 0.7234255144054279 1.4595341038074936 0.1444181611701043 1.0 0.5173017703189681 4 P55786 1 +Annexin [IPR001464] 0.6325654317404608 1.4008759057112858 0.1612511849723037 1.0 0.540378767726111 6 P09525 1 +Molecular chaperone regulator BAG [IPR039773] 0.7970078204692328 1.4008705460214808 0.1612527879963128 1.0 0.540378767726111 3 Q9UL15,O95429 2 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.9853840924541118 1.2666994555886066 0.205262774758528 1.0 0.5901304774307682 2 P48735 1 +Structural maintenance of chromosomes protein [IPR024704] 0.6686974216839301 1.232564674459567 0.2177382233283999 1.0 0.6036534521035011 4 Q9UQE7 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.7504250255015429 1.2208105618911151 0.2221577538867514 1.0 0.6111995621286224 3 P51114,Q06787 2 +Major facilitator superfamily [IPR011701] 0.6632853165349732 1.210113168318885 0.2262354708787426 1.0 0.6151541765621207 4 Q96ES6,P53985 2 +KH domain-containing BBP-like [IPR045071] 0.74430465827951 1.1971914961819443 0.2312319236422633 1.0 0.6207975501638919 3 Q96PU8,Q15637 2 +Microtubule associated protein 1 [IPR026074] 0.739544372662364 1.178835381411709 0.2384637325980116 1.0 0.6304213620407205 3 P78559,Q66K74 2 +Prolyl 4-hydroxylase [IPR045054] 0.9503738953093096 1.1412967239490035 0.2537464649855292 1.0 0.6475451959603155 2 P13674 1 +Kinesin light chain [IPR002151] 0.7266235974158475 1.1290915551697314 0.2588592133715295 1.0 0.6539445563331182 3 Q9H0B6,Q9NSK0 2 +Protein PRRC2 [IPR033184] 0.711092942767471 1.0695039786873957 0.2848426370114532 1.0 0.6776731509143256 3 Q5JSZ5 1 +Cytochrome P450 [IPR001128] 0.9201223657375937 1.0341417914639637 0.3010698814729402 1.0 0.69454436046917 2 Q16850 1 +Syntaxin [IPR045242] 0.5915066460091629 1.0022468556791135 0.3162243828241906 1.0 0.708687641045652 5 O15400 1 +Dynamin [IPR022812] 0.6889725186922379 0.9851755484222054 0.3245378490297415 1.0 0.7149780198931086 3 O00429 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.888851121685929 0.9251119254454158 0.3549076904490493 1.0 0.7418087719216983 2 Q5VTR2 1 +Prefoldin beta-like [IPR002777] 0.8874915023793233 0.9204213317101604 0.3573526254944079 1.0 0.7444846364466833 2 O15212 1 +Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591] 0.8800135961930657 0.8947075352486871 0.3709434495597987 1.0 0.7527890522900001 2 Q5H8A4 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.6534533826341882 0.8517611913417671 0.3943466501505277 1.0 0.7744835843388411 3 Q9Y5J9 1 +P-type ATPase, subfamily IIB [IPR006408] 0.8490822569680448 0.7900646409956342 0.4294900184611079 1.0 0.7989993814580595 2 P20020 1 +Stomatin/HflK/HflC family [IPR001972] 0.847042828008158 0.7832745209133679 0.4334659219970467 1.0 0.7989993814580595 2 P27105 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.8446634942216136 0.7753715651394927 0.4381201323441441 1.0 0.8010568564642478 2 Q96BP3 1 +THRAP3/BCLAF1 family [IPR029199] 0.8433038749150243 0.7708648487469238 0.4407870443252539 1.0 0.8040092942032948 2 Q9NYF8 1 +Spectrin, beta subunit [IPR016343] 0.8402447314751872 0.7607498090401167 0.4468065181324383 1.0 0.809814808277863 2 Q01082 1 +Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101] 0.8382053025152756 0.7540260699826757 0.450833567761667 1.0 0.8117034511121546 2 P49006 1 +Septin [IPR016491] 0.5275523867954955 0.7341770392385529 0.4628408453997197 1.0 0.8213996484717248 5 Q14141 1 +Protein disulphide isomerase [IPR005792] 0.6197912045855372 0.7287167902222716 0.466174920038654 1.0 0.8218493874561503 3 P13667 1 +Haem oxygenase [IPR002051] 0.8167912984364164 0.6844427174278496 0.4936956494100495 1.0 0.8326625827870915 2 P30519 1 +Haem oxygenase-like [IPR016053] 0.8167912984364164 0.6844427174278496 0.4936956494100495 1.0 0.8326625827870915 2 P30519 1 +SUN domain-containing protein 1-5 [IPR045119] 0.8079537729435529 0.6563123199496013 0.5116231922615708 1.0 0.8484018328778752 2 Q9UH99 1 +AP complex subunit beta [IPR026739] 0.5923155389323445 0.631772639198539 0.527535454718949 1.0 0.8560533995519014 3 O00203,Q10567 2 +HnRNP R/Q splicing factor [IPR006535] 0.7841604350781798 0.582513218387075 0.560221040546917 1.0 0.8796266151836419 2 O43390 1 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.5773546412784835 0.5806625958693643 0.5614678756020655 1.0 0.8796266151836419 3 Q92688,Q9BTT0 2 +Tetraspanin, animals [IPR000301] 0.7749830047586405 0.5548761607741955 0.5789793688361762 1.0 0.8859625535653738 2 O43657 1 +Tetraspanin/Peripherin [IPR018499] 0.7749830047586405 0.5548761607741955 0.5789793688361762 1.0 0.8859625535653738 2 O43657 1 +HAD hydrolase, subfamily IA [IPR006439] 0.7685248130523379 0.5357280621556082 0.592146506288723 1.0 0.8919037095376967 2 P34913 1 +Haloacid dehalogenase-like hydrolase [IPR041492] 0.7685248130523379 0.5357280621556082 0.592146506288723 1.0 0.8919037095376967 2 P34913 1 +Ras GTPase-activating protein [IPR039360] 0.754588715159735 0.4953047071121125 0.6203850487478966 1.0 0.907688048422495 2 Q9UJF2 1 +Ras GTPase-activating protein-binding protein [IPR039539] 0.7318150917743064 0.4321052102510708 0.6656649480490697 1.0 0.9301515069944474 2 Q9UN86 1 +Vacuolar protein sorting-associated protein 4 [IPR031255] 0.7209381373215533 0.4032784192721352 0.6867434158299521 1.0 0.938277740306592 2 O75351 1 +Coatomer gamma subunit [IPR017106] 0.693745751189671 0.3354258579203666 0.7373038648329437 1.0 0.9572821873334176 2 Q9Y678 1 +Ancient conserved domain protein family [IPR045095] 0.6832087015635443 0.31085884551288 0.7559079319740849 1.0 0.9572821873334176 2 Q6P4Q7 1 +Heat shock protein Hsp90 family [IPR001404] 0.3989795918367309 0.2448327156594415 0.806585961245379 1.0 0.9572821873334176 4 P07900,P14625,P08238 3 +Rho-associated protein kinase 1/2 [IPR020684] 0.6420802175390878 0.2249858730470443 0.821990264224054 1.0 0.9572821873334176 2 O75116 1 +Cullin [IPR045093] 0.375978223885675 0.2078028321013188 0.8353829211892656 1.0 0.9572821873334176 5 Q13618,Q13616,Q13620,Q93034 4 +Transcription factor STAT [IPR001217] 0.6288239292997924 0.2008722539794677 0.8407984636160704 1.0 0.9572821873334176 2 P42224 1 +Copine [IPR045052] 0.4372662359741558 0.1940743137240243 0.8461176939069033 1.0 0.9572821873334176 3 O75131,Q86YQ8 2 +Prenyltransferase subunit beta [IPR045089] 0.6091094493541872 0.168326444819769 0.8663264707158305 1.0 0.9572821873334176 2 P53611 1 +DNA mismatch repair MutS family [IPR045076] 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 0.9572821873334176 3 P43246,P52701 2 +Flotillin family [IPR027705] 0.6043507817811076 0.1610670934416387 0.872040557440495 1.0 0.9572821873334176 2 O75955 1 +Proteasome, subunit alpha/beta [IPR001353] 0.3537754848620026 0.1587370573615296 0.8738760407716564 1.0 0.9572821873334176 14 P28070,P49721,P28074,P28072 4 +NDRG [IPR004142] 0.6026512576478651 0.1585306096898505 0.8740387025838114 1.0 0.9572821873334176 2 Q9UGV2 1 +GDP dissociation inhibitor [IPR018203] 0.4175450527031684 0.1574825420607126 0.8748645656316603 1.0 0.9572821873334176 3 P31150,P24386 2 +Vinculin/alpha-catenin [IPR006077] 0.5978925900747816 0.1515853208422929 0.879514011874571 1.0 0.9572821873334176 2 P35221 1 +AP-1/2/4 complex subunit beta [IPR016342] 0.5921142080217521 0.1434615375389703 0.8859256855843212 1.0 0.9572821873334176 2 Q10567 1 +P-type ATPase, subfamily IB [IPR027256] 0.589734874235221 0.1402147845357756 0.888490290931397 1.0 0.9572821873334176 2 Q04656 1 +Ribosomal protein S5/S7 [IPR000235] 0.5822569680489533 0.1303816776752757 0.8962644619421329 1.0 0.9572821873334176 2 P46782 1 +E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322] 0.5768184908225769 0.1235810502443212 0.9016469971703712 1.0 0.9572821873334176 2 Q9ULT8 1 +Proteasome activator PA28 [IPR009077] 0.3927235634138094 0.1186662534818264 0.9055397734063462 1.0 0.9572821873334176 3 P61289,Q9UL46 2 +Peptidase, FtsH [IPR005936] 0.5723997280761391 0.1182707049319668 0.9058531685349092 1.0 0.9572821873334176 2 Q9Y4W6 1 +Importin beta family [IPR040122] 0.3324259952364722 0.111670914219627 0.9110843421380644 1.0 0.957519661265451 5 Q92973,Q14974,O00410,Q8TEX9 4 +Cytoplasmic FMR1-interacting [IPR008081] 0.5537049626104766 0.0978909153051745 0.922018913875658 1.0 0.9595398120343366 2 Q7L576 1 +Prefoldin alpha-like [IPR004127] 0.3675187608277618 0.0873489234968252 0.9303941672689532 1.0 0.962605444738783 3 Q9UBK9 1 +Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312] 0.3645018701122011 0.0841258055170383 0.9329564075295051 1.0 0.962605444738783 3 Q6PI48,O43776 2 +P-type ATPase [IPR001757] 0.3098146523417641 0.0797719984717695 0.936418595313444 1.0 0.9630004813712472 8 P20020 1 +Snf7 family [IPR005024] 0.2995468749853253 0.0749718924259516 0.9402370755309596 1.0 0.9637011023713042 6 Q9NZZ3,Q8WUX9,Q9Y3E7 3 +C-terminal binding protein [IPR043322] 0.5129163834126531 0.0643306003086758 0.948706988387396 1.0 0.9706521678340796 2 P56545 1 +Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311] 0.4945615227736327 0.0535442469622717 0.9572982772128572 1.0 0.9768349767478136 2 P33121 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.4911624745071468 0.0518048688345669 0.9586841759939608 1.0 0.9769488723022196 2 O43819 1 +Copper chaperone SCO1/SenC [IPR003782] 0.4911624745071468 0.0518048688345669 0.9586841759939608 1.0 0.9769488723022196 2 O43819 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.4605710401087775 0.0393194826781642 0.9686356736954328 1.0 0.9849080678600776 2 P07910 1 +Synaptobrevin [IPR001388] 0.4571719918422908 0.038247284613689 0.969490520784978 1.0 0.9853416693793412 2 P51809 1 +Ribosomal protein S2 [IPR001865] 0.402447314751875 0.0273367781190042 0.9781911231241496 1.0 0.9888676155171316 2 Q9Y399 1 +Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129] 0.3902107409925304 0.0261076160743675 0.9791715023855394 1.0 0.9888676155171316 2 O14880 1 +Sorting nexin-5/6/32 [IPR014637] 0.3885112168592854 0.0259612602587261 0.9792882378632302 1.0 0.9888676155171316 2 Q9Y5X3 1 +Phosphatidylinositol kinase [IPR015433] 0.2378847426546398 0.0238131287447086 0.9810016677956804 1.0 0.9888676155171316 3 Q8NEB9 1 +Ribosomal protein L14P [IPR000218] 0.3443235893949746 0.0236539333559543 0.9811286515696064 1.0 0.9888676155171316 2 Q6P1L8 1 +Kinesin-like protein [IPR027640] 0.2734557633217672 0.0164478388653545 0.9868771150055102 1.0 0.9937904398041476 8 Q02241 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cd0bacb22252afb4b052b3268737e3da397c2009 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S18b, mitochondrial [IPR040054]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit s, mitochondrial [IPR026063]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP synthase-coupling factor 6, mitochondrial [IPR008387]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating signal cointegrator 1-like [IPR039128]", "Activating transcription factor 7-interacting protein [IPR026085]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase [IPR011408]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat domain-containing protein 13 [IPR021832]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell lymphoma/leukemia 10/E10 [IPR033238]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Bet3 family [IPR016721]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicaudal-D protein [IPR018477]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-3/7 [IPR015471]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell division cycle protein 123 [IPR009772]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centromere protein I [IPR012485]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Clusterin [IPR016016]", "Clusterin-like [IPR000753]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 167 [IPR028194]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit G2 [IPR024741]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 16 [IPR028216]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Deltex family [IPR039398]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dysbindin [IPR007531]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase synoviolin/Hrd1 [IPR032832]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "ECSIT [IPR010418]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 7 [IPR039163]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [IPR029890]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G patch domain-containing protein 11 [IPR039249]", "G-protein alpha subunit, group I [IPR001408]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GMP reductase [IPR005993]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gasdermin-E [IPR042377]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "Guided entry of tail-anchored proteins factor CAMLG [IPR016719]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HIRA-interacting protein 3 [IPR037647]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin-interacting protein 1-related protein [IPR030555]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "Hypoxia-inducible factor 1-alpha inhibitor [IPR027445]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 10 [IPR026164]", "Integrator complex subunit 12 [IPR039053]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "Junction plakoglobin [IPR030461]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Lipoma-preferred partner [IPR028771]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med24, [IPR021429]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate kinase [IPR006205]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim10 [IPR027100]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 14 [IPR039802]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament medium polypeptide [IPR027697]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nicotinate-nucleotide pyrophosphorylase [IPR004393]", "Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD [IPR027277]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear RNA export factor [IPR030217]", "Nuclear RNA-splicing-associated protein, SR-25 [IPR019532]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "OPI10 family [IPR031318]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 6 [IPR008721]", "Origin recognition complex, subunit 6, metazoa/plant [IPR020529]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein GIPC1/2/3 [IPR017379]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Palmitoyltransferase ZDHHC13 [IPR030290]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phorbol-12-myristate-13-acetate-induced protein 1 [IPR024140]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol 3-kinase, Vps34 type [IPR008290]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphatidylserine lipase ABHD16A [IPR026604]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphoserine phosphatase [IPR004469]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein BRAWNIN [IPR027858]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM210A/B-like [IPR045866]", "Protein FAM3C [IPR039219]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein Lsm12-like [IPR039683]", "Protein NDRG1 [IPR030693]", "Protein NDRG3 [IPR030692]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase Mps1 family [IPR027084]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1356, TMEM106 [IPR009790]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF2452 [IPR019534]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Proto-oncogene c-Rel [IPR030505]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Purine-rich element-binding protein beta [IPR030499]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II subunit A [IPR006811]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, Rpb8 [IPR005570]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab protein geranylgeranyltransferase component A [IPR001738]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab33A/B [IPR041822]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Ran-interacting Mog1 protein [IPR007681]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Recoverin family [IPR028846]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinol-binding protein 1 [IPR031264]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L33 [IPR001705]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase Rio1 [IPR017407]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Sm-like protein Lsm6/SmF [IPR016487]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small acidic protein [IPR026714]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of fused [IPR007768]", "Suppressor of fused, eukaryotic [IPR016591]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex subunit 7/Mft1 [IPR008501]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TIP41-like protein [IPR007303]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "TSC-22 / Dip / Bun [IPR000580]", "Tankyrase 1-binding protein-like [IPR040006]", "Tapasin [IPR008056]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, enhancer of yellow 2 [IPR018783]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 161A/B [IPR019395]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "TspO/MBR-related protein [IPR004307]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier 1 [IPR005375]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0390 [IPR019034]", "Uncharacterised protein family UPF0687 [IPR026794]", "Uncharacterized protein C11orf98 [IPR037691]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "Vacuolar fusion protein Ccz1 [IPR013176]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 11 [IPR016528]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vinexin [IPR028510]", "Visinin-like protein 2 [IPR029534]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "Yos1-like [IPR013880]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 638 [IPR033096]", "Zinc finger protein 830-like [IPR040050]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP response element binding (CREB) protein [IPR001630]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "cAMP-responsive element-binding protein 1 [IPR029802]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP12", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1S1", "ALDH16A1", "ALDH18A1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANKRD13A", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFIP1", "ARFIP2", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC1", "ARMC6", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATF7IP", "ATG3", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BASP1", "BAX", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C11orf58", "C11orf98", "C12orf73", "C19orf53", "C19orf70", "C1QBP", "C1orf122", "C1orf35", "C1orf50", "C20orf27", "C2CD2", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAMLG", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZB", "CARM1", "CARS", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC167", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD3EAP", "CD47", "CDC123", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK5RAP3", "CDKAL1", "CDV3", "CEBPZ", "CENPI", "CEP44", "CEP55", "CERS1", "CERS2", "CERS4", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF16", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX54", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTX3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EHBP1", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "ENDOD1", "ENO1", "ENPP1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EZR", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM210A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GFM1", "GFPT1", "GGCT", "GGH", "GHDC", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMFB", "GMPR2", "GNAI3", "GNL1", "GNL2", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPATCH11", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRPEL1", "GRSF1", "GSDME", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPCAL4", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFT27", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS10", "INTS12", "INTS14", "INTS9", "IPO4", "IPO5", "IRGQ", "IRS4", "ISCU", "IST1", "ISYNA1", "ITGB1", "ITM2C", "ITPA", "ITPK1", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF5B", "KIFBP", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LPP", "LRPPRC", "LRRC47", "LSM12", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LYAR", "LZTFL1", "MACF1", "MAD2L1", "MAGED2", "MAN1A1", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED21", "MED24", "METAP2", "MFN2", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORF4L1", "MORF4L2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL48", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MTX3", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "NAA15", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NF1", "NHP2", "NIP7", "NIPBL", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRM", "NSA2", "NSF", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCIAD2", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PAWR", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGT", "PIGU", "PIK3C3", "PIK3R4", "PIN4", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP5C", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM3", "PURA", "PURB", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM8A", "RBP1", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDX", "RECQL", "REEP4", "REEP5", "REL", "REPS1", "RER1", "REXO2", "RFC1", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RNASEH2A", "RNF20", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC7A1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMCHD1", "SMPD4", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPNS1", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX5", "STX6", "STX7", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYVN1", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TAPBP", "TARBP1", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TECR", "TEDC1", "TES", "TEX10", "TFG", "TFRC", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TLE3", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM126A", "TMEM126B", "TMEM161A", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1AIP2", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT10C", "TRMT1L", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSR1", "TST", "TTC19", "TTC26", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXNDC12", "TXNDC17", "TXNDC9", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4B", "UBQLN1", "UBR4", "UBR7", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNG", "UPF1", "UPF2", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VKORC1L1", "VPS11", "VPS13A", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VTA1", "WAPL", "WARS", "WASHC5", "WBP11", "WBP2", "WDR12", "WDR18", "WDR33", "WDR46", "WDR82", "WDR91", "WFS1", "WIPI2", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YIF1A", "YIPF4", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H7A", "ZCCHC3", "ZCRB1", "ZDHHC13", "ZFYVE16", "ZMPSTE24", "ZNF326", "ZNF598", "ZNF638", "ZNF830", "ZPR1", "ZRANB2", "ZW10"], "leading_proteins": ["ACSL1", "AFG3L2", "ANP32B", "ANP32E", "ANXA4", "AP1B1", "AP3B1", "AQR", "ATP2B1", "ATP7A", "BAG4", 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b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8aa036c1d88f3c575685e1426454ff5058a08bc86a3ae0dc7179ad4446e2c329 +size 89364 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c2504e4e74d24ef04a0d2ea4fdd941206bd300fa --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 3 6 2.584510527278764 0.0097517327477087 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0015075035399645 0.0058956460302812 0.0001472775053537 0.0020333503076747 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 3 7 2.2417888391604186 0.0249750229057257 3.7524271844660193 6.847087378640777 0.510735400099038 0.3891602594566672 2.000453572849188 1.1755668998633355 1.2190917823770269 0.3170422836523225 0.0892490045576324 0.1709159600444602 0.0104402688493973 0.012134686324044 +Tubulin/FtsZ, C-terminal [IPR008280] 2 6 2.0837649840842003 0.0371815498916539 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 1.0 1.0 0.0703212183088513 0.0547354250806853 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 2 6 2.0837649840842003 0.0371815498916539 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 1.0 1.0 0.0569248849368824 0.0403506671570748 +Tubulin, C-terminal [IPR023123] 2 6 2.0837649840842003 0.0371815498916539 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 1.0 1.0 0.0703212183088513 0.0547354250806853 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7b56391f18b8730311dda375fa770c97ea46d801 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 947, + "title": "Average number of proteins per term", + "value": 4.616684266103484 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..afc365be4011c22581cd8334b8b51cfe6a0db85a --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..109a3e860d58b47c41dad27fb7322c4c4d331a56 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,136 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.8994336803183094 2.584510527278764 0.0097517327477087 0.9999067488249654 0.6455358129091325 6 Q8WUJ1,O00264,Q9UMX5 3 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.8166428929821087 2.2417888391604186 0.0249750229057257 0.9999999999603808 0.6455358129091325 7 Q9BUK6,P04350,Q13509 3 +Tubulin/FtsZ, C-terminal [IPR008280] 0.7826484314400508 2.0837649840842003 0.0371815498916539 0.9999999999999998 0.6455358129091325 6 P04350,Q13509 2 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.7826484314400508 2.0837649840842003 0.0371815498916539 0.9999999999999998 0.6455358129091325 6 P04350,Q13509 2 +Tubulin, C-terminal [IPR023123] 0.7826484314400508 2.0837649840842003 0.0371815498916539 0.9999999999999998 0.6455358129091325 6 P04350,Q13509 2 +EF-hand domain pair [IPR011992] 0.4407283821369178 1.9229978400852337 0.0544803211159969 1.0 0.6455358129091325 50 Q15293,P80303,Q9Y680,Q03001,Q96D71,O43852,Q14257,Q9NWM8 8 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.818707482993203 1.849518161771563 0.0643830277731551 1.0 0.6455358129091325 4 P01889,P04439,P55899 3 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.818707482993203 1.849518161771563 0.0643830277731551 1.0 0.6455358129091325 4 P01889,P04439,P55899 3 +Rhomboid-like superfamily [IPR035952] 0.9059976239296208 1.8187813740283971 0.0689447911390328 1.0 0.6455358129091325 3 Q9BUN8 1 +Immunoglobulin-like domain superfamily [IPR036179] 0.7002769686792378 1.741407225230719 0.0816122226190463 1.0 0.6455358129091325 10 Q13308,P10586,Q08722,P55899,P04439 5 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.6937796188207104 1.7009763822779411 0.0889474221775676 1.0 0.6455358129091325 9 P52756,Q92804,Q01844,P35637 4 +Aldehyde dehydrogenase, N-terminal [IPR016162] 0.6901322531430072 1.6929913239393228 0.0904571186667948 1.0 0.6455358129091325 10 P30837,O94788 2 +Aldehyde dehydrogenase, C-terminal [IPR016163] 0.6901322531430072 1.6929913239393228 0.0904571186667948 1.0 0.6455358129091325 10 P30837,O94788 2 +Aldehyde/histidinol dehydrogenase [IPR016161] 0.6901322531430072 1.6929913239393228 0.0904571186667948 1.0 0.6455358129091325 10 P30837,O94788 2 +NAP-like superfamily [IPR037231] 0.8667120027201676 1.669169688292641 0.0950837554882702 1.0 0.6455358129091325 3 Q01105,Q99733 2 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.4565665207543786 1.6342581401598573 0.102204659184953 1.0 0.6659621230468294 81 O75153,Q9H7B4,Q6PGP7,P33981,Q5R3I4,Q99747,Q9NYH9,Q96TC7,O15460,O95801,Q6ZXV5,Q07866,Q9H270,Q9UJX3,Q9H0B6,A0AVF1,Q9Y5A7,P13674,Q6DKK2,Q14CX7,Q13042,O15091,O15294,Q32P28,P49321,Q92791,Q9NSK0,O00231,Q12797,Q13451,O75718 31 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.6817357293873945 1.628705753139509 0.1033753242744286 1.0 0.6659621230468294 6 P55786 1 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.6817357293873945 1.628705753139509 0.1033753242744286 1.0 0.6659621230468294 6 P55786 1 +LEM/LEM-like domain superfamily [IPR011015] 0.6777379835622169 1.610304613530563 0.1073313725640998 1.0 0.682166508846997 6 P50402,Q8NC56,Q9Y2U8 3 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.4978944584441891 1.5645148624580678 0.1176967054038111 1.0 0.7067322865848146 119 Q9Y5S9,Q01844,Q8IUH3,Q96I25,P52756,Q8TBF4,Q99729,Q9Y2U8,Q92804,Q07955,P31483,O43719,Q01085,Q96E39,Q13242,O43390,P98175,O14979,Q08170,P62995,P51991,P84103,Q8IXT5,Q9GZT3,Q76FK4,P19338,Q9H501,Q13243,Q8WXF1,P38159,Q9UN86,P98179,Q12849,P35637,Q86U42,P31942,Q96T58,P23246,Q8N684,Q8WVV9,Q8NFH5,P23588,Q96PK6,Q13247,Q9BWF3,Q15056,P11940,Q14011,P22626,O60506,Q9P2K5,Q9Y4C8 52 +Chloramphenicol acetyltransferase-like domain superfamily [IPR023213] 0.6644293711117952 1.5488760189603663 0.1214115267641398 1.0 0.7067322865848146 6 O00330 1 +MFS transporter superfamily [IPR036259] 0.6620146164646051 1.5441704701681498 0.1225470405971733 1.0 0.7067322865848146 8 Q6N075,Q16625,Q9H2V7,O00400,Q96ES6,P53985 6 +RNA-binding domain superfamily [IPR035979] 0.4938019939613056 1.5130442542208753 0.130268418152492 1.0 0.7272880688658337 120 Q9Y5S9,Q01844,Q8IUH3,Q96I25,P52756,Q8TBF4,Q99729,Q9Y2U8,Q92804,Q07955,P31483,O43719,Q01085,Q96E39,Q13242,O43390,P98175,O14979,Q08170,P62995,P51991,P84103,Q8IXT5,Q9GZT3,Q76FK4,P19338,Q13243,Q8WXF1,P38159,Q9UN86,P98179,Q12849,P35637,Q86U42,P31942,Q96T58,Q71RC2,P23246,Q8N684,Q8WVV9,Q8NFH5,P23588,Q96PK6,Q13247,Q9BWF3,Q15056,P11940,Q14011,P22626,O60506,Q9P2K5,Q9Y4C8 52 +TFIIS/LEDGF domain superfamily [IPR035441] 0.7073404397631251 1.500044486668448 0.1336028793095236 1.0 0.7305969993331037 5 Q14241,Q7Z4V5 2 +DUSP-like superfamily [IPR035927] 0.8067423752776902 1.438482304217775 0.1502972548387873 1.0 0.7570824485762319 3 Q9Y4E8 1 +Annexin superfamily [IPR037104] 0.6325654317404608 1.4008759057112858 0.1612511849723037 1.0 0.7934744515403569 6 P09525 1 +BAG domain superfamily [IPR036533] 0.7970078204692328 1.4008705460214808 0.1612527879963128 1.0 0.7934744515403569 3 Q9UL15,O95429 2 +SWAP/Surp superfamily [IPR035967] 0.6302459928312976 1.3900604377640704 0.1645105254980254 1.0 0.794854426768521 6 Q12872,Q8IWZ8,Q15459 3 +GroES-like superfamily [IPR011032] 0.6243808052055764 1.3695429373507226 0.1708296227168477 1.0 0.8170487510750244 9 Q8N4Q0 1 +Cyclic nucleotide-binding-like [IPR018490] 0.6638547050364713 1.2124747576334052 0.2253306994623027 1.0 0.8709721322073499 4 Q6P4Q7,Q9Y4G8 2 +SPOC-like, C-terminal domain superfamily [IPR016194] 0.7345620886399369 1.15963895856005 0.246195832299545 1.0 0.8974541110781453 3 Q96T58 1 +Bromodomain-like superfamily [IPR036427] 0.5732325993283758 1.1452349082201545 0.2521118615058377 1.0 0.8974541110781453 13 Q03164 1 +Chromo-like domain superfamily [IPR016197] 0.5766651446837903 1.1377768841479623 0.2552136596927106 1.0 0.8974541110781453 7 P83916,P45973,Q9UBU8 3 +Ubiquitin-like domain superfamily [IPR029071] 0.4299713813865952 1.1206560075990413 0.2624343148182044 1.0 0.8974541110781453 37 P55196,P35241,Q9UNZ2,Q96K76,Q15459,Q96CS3,Q96T88,O14920,Q05397,Q9Y4E8,Q9Y5A7,O14641,Q86UV5,Q9Y4G8,Q96L92,P61960,P46379 17 +MIT domain superfamily [IPR036181] 0.7211832709962718 1.1081893625047912 0.2677800438961326 1.0 0.8974541110781453 3 O75351,Q8N0X7 2 +E3-binding domain superfamily [IPR036625] 0.720537003415064 1.1057082833032954 0.2688528035932063 1.0 0.8974541110781453 3 O00330 1 +Band 7/SPFH domain superfamily [IPR036013] 0.5691869353312204 1.1024473790197593 0.270267223320475 1.0 0.8974541110781453 7 P27105 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.6321789870225427 1.081395505594848 0.2795212200290766 1.0 0.8974541110781453 4 P48444 1 +Prefoldin [IPR009053] 0.6075728325412166 1.071005953135201 0.2841667528956213 1.0 0.8987154910522179 5 Q9UBK9,O15212,Q9UHV9 3 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 0.7081389628638604 1.058201644925663 0.2899635215120286 1.0 0.9003129667930856 3 Q5H8A4 1 +Cytochrome P450 superfamily [IPR036396] 0.9201223657375937 1.0341417914639637 0.3010698814729402 1.0 0.9167626294368952 2 Q16850 1 +WW domain superfamily [IPR036020] 0.5521717240079805 1.0230248043463763 0.3062961181529029 1.0 0.9215295933991404 10 Q13526,Q6ZWJ1,O00213,O75400,O95817,P46939 6 +Immunoglobulin-like fold [IPR013783] 0.5013014057066535 1.0219176509558086 0.3068198775595694 1.0 0.9215295933991404 26 Q13308,Q8NHP6,P10586,Q08722,P55899,P04439 6 +SNARE [IPR010989] 0.5915066460091629 1.0022468556791135 0.3162243828241906 1.0 0.9215295933991404 5 O15400 1 +Rhodanese-like domain superfamily [IPR036873] 0.6921299674598473 0.9971650454844484 0.3186844045672747 1.0 0.9215295933991404 3 Q99956 1 +Lamin tail domain superfamily [IPR036415] 0.6905814348861038 0.9912827431669088 0.3215475370255551 1.0 0.9215295933991404 3 Q03252,P02545 2 +Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866] 0.526488578287863 0.9059167349156584 0.3649799258951662 1.0 0.9457425569053136 6 Q5TA45 1 +Chaperone J-domain superfamily [IPR036869] 0.5202259489048804 0.8936558544690778 0.3715060519205666 1.0 0.9457425569053136 15 Q8IXB1,O75937,O14976,Q9UGP8,Q9NVH1 5 +Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039] 0.8684568320870042 0.8552677447517498 0.3924029398836577 1.0 0.96484213403078 2 P13984 1 +Death-like domain superfamily [IPR011029] 0.5744897959183617 0.846367309350756 0.3973478693474173 1.0 0.96484213403078 4 Q96FV9,Q12955,O95999 3 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.5727955088280325 0.8395884292339085 0.4011391890425373 1.0 0.9690786021002114 4 Q13724 1 +Zinc finger, CCHC-type superfamily [IPR036875] 0.57181510687772 0.8356701043928018 0.4033405180850189 1.0 0.9719172280572848 4 Q8TBF4,Q9NUD5 2 +Zinc finger, RING/FYVE/PHD-type [IPR013083] 0.3339570524111338 0.8060709414649186 0.4202019455378507 1.0 0.9767078489708446 43 Q9Y508,O14964,Q86TM6,Q96MF7,Q14839,O75150,Q5VTR2,Q9H270,Q96T88,Q03164,Q53GS9,P19474,O96028,O15344,Q14527 15 +Haem oxygenase-like, multi-helical [IPR016084] 0.8167912984364164 0.6844427174278496 0.4936956494100495 1.0 1.0 2 P30519 1 +RmlC-like jelly roll fold [IPR014710] 0.4785508296348805 0.6780535797570777 0.4977377217882575 1.0 1.0 8 Q9NWT6,Q9Y4G8 2 +MAN1, winged-helix domain [IPR041885] 0.8031951053704904 0.6413195326806853 0.5213151012031467 1.0 1.0 2 Q9Y2U8 1 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.5192780340701368 0.6315629108025058 0.5276725285781292 1.0 1.0 4 Q8TC07,Q66K14 2 +Protein-tyrosine phosphatase-like [IPR029021] 0.4682604847764611 0.6254851034490917 0.531652722334979 1.0 1.0 10 P10586,Q99956 2 +K Homology domain, type 1 superfamily [IPR036612] 0.4303675169683628 0.5915417969676078 0.5541574585250286 1.0 1.0 26 Q8N9N2,Q96AE4,P51114,Q15637,O75179,Q06787,P61978 7 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4498911064615086 0.556514636360536 0.5778590916178037 1.0 1.0 17 O95831,Q14534,Q9UHG3 3 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.7749830047586405 0.5548761607741955 0.5789793688361762 1.0 1.0 2 O43657 1 +Ricin B-like lectins [IPR035992] 0.5575446846806056 0.5151621480678524 0.6064397171559968 1.0 1.0 3 Q10472 1 +Cullin repeat-like-containing domain superfamily [IPR016159] 0.4372379243504638 0.4978749063894916 0.6185722151267687 1.0 1.0 8 Q13620,Q9UPT5,Q9UID3,Q93034 4 +NET domain superfamily [IPR038336] 0.7515295717199211 0.4866027243730014 0.6265398925254364 1.0 1.0 2 O60885 1 +SMCs flexible hinge superfamily [IPR036277] 0.4626511637847912 0.4815338458428342 0.6301371306782482 1.0 1.0 5 Q9UQE7 1 +SH3-like domain superfamily [IPR036028] 0.396114843426326 0.4441841673097585 0.6569094381617031 1.0 1.0 28 O60504,Q92783,Q12965,Q9UNF0,Q9UKS6,Q14247,Q9Y5K6,Q13813,P41240,P62993,Q14847,Q9UQB8,Q5JRA6,Q00013,Q14155 15 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.4151249223491747 0.4147918492396867 0.6782942868657094 1.0 1.0 7 O43847 1 +PX domain superfamily [IPR036871] 0.4080011507286245 0.3799642319159438 0.7039719662584174 1.0 1.0 8 O60493,Q96L92 2 +SWIB/MDM2 domain superfamily [IPR036885] 0.7100611828687733 0.3753927806399235 0.7073683732107552 1.0 1.0 2 P41214 1 +DNA/RNA non-specific endonuclease superfamily [IPR044929] 0.7056424201223521 0.3643433462297086 0.7156016353353007 1.0 1.0 2 P22413 1 +His-Me finger superfamily [IPR044925] 0.7056424201223521 0.3643433462297086 0.7156016353353007 1.0 1.0 2 P22413 1 +ENTH/VHS [IPR008942] 0.4022193916315387 0.3380157366176884 0.7353513289285205 1.0 1.0 12 O14964,Q5VT52 2 +Coatomer, gamma subunit, appendage domain superfamily [IPR037067] 0.693745751189671 0.3354258579203666 0.7373038648329437 1.0 1.0 2 Q9Y678 1 +L27 domain superfamily [IPR036892] 0.4957497449847055 0.33115958932566 0.7405239426730215 1.0 1.0 3 O14936,Q14168 2 +Longin-like domain superfamily [IPR011012] 0.393240819918573 0.3033066406490873 0.7616561859077611 1.0 1.0 12 P48444,Q92572,Q9Y296,P08240,P61923 5 +DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921] 0.3815503842294182 0.2990253872887597 0.7649206750213373 1.0 1.0 6 Q96S55 1 +Mitochondrial carrier domain superfamily [IPR023395] 0.3897472917618136 0.2969603477818175 0.7664967821573376 1.0 1.0 20 O43772,Q9BQT8,Q70HW3 3 +Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236] 0.6730115567641107 0.288053669073685 0.7733056568406547 1.0 1.0 2 Q8NEB9 1 +Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069] 0.3828080329177477 0.2801915888963425 0.7793305194195623 1.0 1.0 9 P11310 1 +Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] 0.3828080329177477 0.2801915888963425 0.7793305194195623 1.0 1.0 9 P11310 1 +Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] 0.3828080329177477 0.2801915888963425 0.7793305194195623 1.0 1.0 9 P11310 1 +Cullin homology domain superfamily [IPR036317] 0.372021783526214 0.2668251539425449 0.7896037861258762 1.0 1.0 6 Q93034,Q13618,Q13620,Q13617,Q13616 5 +F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276] 0.6621346023113577 0.2648113943923731 0.7911547587147847 1.0 1.0 2 P52907 1 +F-actin-capping protein subunit alpha/beta [IPR037282] 0.6621346023113577 0.2648113943923731 0.7911547587147847 1.0 1.0 2 P52907 1 +FERM/acyl-CoA-binding protein superfamily [IPR014352] 0.3802240443788327 0.2597189188083951 0.7950805981984079 1.0 1.0 11 Q9H3P7,Q05397 2 +HSP90, C-terminal domain [IPR037196] 0.3989795918367309 0.2448327156594415 0.806585961245379 1.0 1.0 4 P07900,P14625,P08238 3 +R3H domain superfamily [IPR036867] 0.4549472968378143 0.2311446157535849 0.8172024550975898 1.0 1.0 3 Q9H6S0,O95453 2 +SCP2 sterol-binding domain superfamily [IPR036527] 0.4546072764365941 0.2303945308247856 0.817785210626623 1.0 1.0 3 Q6YN16,P51659 2 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.3739155914744354 0.2243795627941711 0.8224619718204431 1.0 1.0 15 Q10471,Q8NBJ5,Q8NFW8,Q10472,Q9NYU2 5 +Tim10-like domain superfamily [IPR035427] 0.3783154726062996 0.2138389078234978 0.8306726825980708 1.0 1.0 5 Q9Y5J9,Q9Y5L4 2 +STAT transcription factor, N-terminal domain superfamily [IPR036535] 0.6288239292997924 0.2008722539794677 0.8407984636160704 1.0 1.0 2 P42224 1 +STAT transcription factor, coiled coil [IPR015988] 0.6288239292997924 0.2008722539794677 0.8407984636160704 1.0 1.0 2 P42224 1 +STAT transcription factor, DNA-binding, N-terminal [IPR012345] 0.6288239292997924 0.2008722539794677 0.8407984636160704 1.0 1.0 2 P42224 1 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.3515442492730551 0.1824285683707681 0.8552464076453328 1.0 1.0 26 Q8N6R0,Q96FX7,Q9BV86,Q08J23 4 +MutS, connector domain superfamily [IPR036678] 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 1.0 3 P43246,P52701 2 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 1.0 3 P43246,P52701 2 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 1.0 3 P43246,P52701 2 +Cobalamin-binding domain superfamily [IPR036724] 0.5924541128484001 0.1439300324029906 0.8855557201656925 1.0 1.0 2 Q99707 1 +Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037] 0.5921142080217521 0.1434615375389703 0.8859256855843212 1.0 1.0 2 Q10567 1 +EF-G domain III/V-like [IPR035647] 0.3477373256209661 0.141852920296526 0.8871961823189058 1.0 1.0 5 Q96RP9,Q7Z2Z2,Q8N442,Q15029 4 +HECT, E3 ligase catalytic domain [IPR035983] 0.3309499489274664 0.1371752586515459 0.8908922667572352 1.0 1.0 7 Q9ULT8,Q05086,Q7Z6Z7,Q96PU5,Q15386,Q14669 6 +Ribosomal protein S7 domain superfamily [IPR036823] 0.5822569680489533 0.1303816776752757 0.8962644619421329 1.0 1.0 2 P46782 1 +Proteasome activator superfamily [IPR036252] 0.3927235634138094 0.1186662534818264 0.9055397734063462 1.0 1.0 3 P61289,Q9UL46 2 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.3927235634138094 0.1186662534818264 0.9055397734063462 1.0 1.0 3 P61289,Q9UL46 2 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.3927235634138094 0.1186662534818264 0.9055397734063462 1.0 1.0 3 P61289,Q9UL46 2 +Peptidase M41-like [IPR037219] 0.5723997280761391 0.1182707049319668 0.9058531685349092 1.0 1.0 2 Q9Y4W6 1 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.3384905515616245 0.1039833454953241 0.9171825652853344 1.0 1.0 17 P28070,Q99436,P28072,P49721,P28074 5 +START-like domain superfamily [IPR023393] 0.326981966655326 0.1019001279126491 0.9188359484327326 1.0 1.0 5 Q14849,Q9NQZ5,Q00169,O95433 4 +PDZ superfamily [IPR036034] 0.3345729362006536 0.0953988260625293 0.92399804849341 1.0 1.0 23 Q9UDY2,Q6ZWJ1,Q9HD26,Q53GG5,Q09666,O14641,Q9Y4G8,Q96RT1,Q96L92,Q00013 10 +SNase-like, OB-fold superfamily [IPR035437] 0.3709622577354665 0.0911618865599857 0.9273639589281848 1.0 1.0 3 Q7KZF4,Q92667 2 +Alpha-catenin/vinculin-like superfamily [IPR036723] 0.3706222373342341 0.0907789758238462 0.92766821592506 1.0 1.0 3 P18206,P35221 2 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.3098146523417641 0.0797719984717695 0.936418595313444 1.0 1.0 8 P20020 1 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.3098146523417641 0.0797719984717695 0.936418595313444 1.0 1.0 8 P20020 1 +P-type ATPase, A domain superfamily [IPR008250] 0.3098146523417641 0.0797719984717695 0.936418595313444 1.0 1.0 8 P20020 1 +ISWI, HAND domain superfamily [IPR036306] 0.5261726716519459 0.0737017245043578 0.9412477265670832 1.0 1.0 2 O60264 1 +DNA-binding domain superfamily [IPR016177] 0.5234534330387577 0.0716649216056077 0.942868572858088 1.0 1.0 2 O95983 1 +Rho GTPase activation protein [IPR008936] 0.297463551149992 0.0629009846985507 0.9498453507232004 1.0 1.0 7 Q9UJF2,P21359,Q14C86,Q13576 4 +Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047] 0.2899931926480633 0.0573740922408938 0.954247200394577 1.0 1.0 6 Q9HCU5,Q8IWA0,Q15269,Q9HC35,Q8N766 5 +Leucine-rich repeat domain superfamily [IPR032675] 0.3174651080627253 0.0465279466642064 0.962889459984595 1.0 1.0 25 Q15404,Q15435,Q9UQ13 3 +Zinc finger, CCCH-type superfamily [IPR036855] 0.2803957058907632 0.0415305070224738 0.966872972740394 1.0 1.0 6 Q8WU90 1 +FERM superfamily, second domain [IPR035963] 0.2926430262505616 0.0392634080055247 0.9686803802882415 1.0 1.0 9 Q05397 1 +K homology domain-like, alpha/beta [IPR015946] 0.4425560842964036 0.0342463153393733 0.9726807338826132 1.0 1.0 2 P23396 1 +K homology domain superfamily, prokaryotic type [IPR009019] 0.4425560842964036 0.0342463153393733 0.9726807338826132 1.0 1.0 2 P23396 1 +Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056] 0.4384772263766211 0.0332923997277907 0.9734414145403892 1.0 1.0 2 P07814 1 +Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035] 0.4384772263766211 0.0332923997277907 0.9734414145403892 1.0 1.0 2 P07814 1 +Nop domain superfamily [IPR036070] 0.2845970758245443 0.0328705217625332 0.9737778403132114 1.0 1.0 3 Q8WWY3,O00567 2 +Nop, C-terminal domain [IPR042239] 0.2845970758245443 0.0328705217625332 0.9737778403132114 1.0 1.0 3 Q8WWY3,O00567 2 +Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591] 0.402447314751875 0.0273367781190042 0.9781911231241496 1.0 1.0 2 Q9Y399 1 +GHMP kinase, C-terminal domain superfamily [IPR036554] 0.3956492182189078 0.026614373930262 0.978767308582532 1.0 1.0 2 Q03426 1 +Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352] 0.3902107409925304 0.0261076160743675 0.9791715023855394 1.0 1.0 2 O14880 1 +BRK domain superfamily [IPR037259] 0.3555404486743773 0.0240218283098815 0.9808351972562795 1.0 1.0 2 P51532 1 +Ribosomal protein L14 superfamily [IPR036853] 0.3443235893949746 0.0236539333559543 0.9811286515696064 1.0 1.0 2 Q6P1L8 1 +Isoprenoid synthase domain superfamily [IPR008949] 0.3269884432358996 0.0232713393387296 0.9814338334149966 1.0 1.0 2 P14324 1 +TBP domain superfamily [IPR012295] 0.2532479251559297 0.0062309095943859 0.9950284856041084 1.0 1.0 6 Q9Y678,Q10567 2 +Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028] 0.2532479251559297 0.0062309095943859 0.9950284856041084 1.0 1.0 6 Q9Y678,Q10567 2 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..97791e22d4382a5b2148b453755ca9c0c37aa625 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP synthase-coupling factor 6 superfamily, mitochondrial [IPR036204]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deltex, C-terminal domain superfamily [IPR039399]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Focal adhesion kinase, targeting (FAT) domain superfamily [IPR036137]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "Hypoxia-inducible factor 1-alpha inhibitor, domain II [IPR027452]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kazal domain superfamily [IPR036058]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MAP kinase activated protein kinase, C-terminal [IPR027442]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "Mir domain superfamily [IPR036300]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mog1/PsbP, alpha/beta/alpha sandwich [IPR016123]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinolinate phosphoribosyl transferase, N-terminal domain superfamily [IPR037128]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L33 superfamily [IPR038584]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Somatomedin B-like domain superfamily [IPR036024]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Suppressor of fused, C-terminal domain superfamily [IPR038489]", "Suppressor of fused, N-terminal [IPR037181]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TRAF-like [IPR008974]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor EnY2 superfamily [IPR038212]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALKBH5", "ALYREF", "AMFR", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATF7IP", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5J", "ATP5O", "ATP5S", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATXN10", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCL10", "BCL2L13", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD2", "CAB39", "CACUL1", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP3", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2A", "CEBPZ", "CENPV", "CERS2", "CERS4", "CFL1", "CFL2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHM", "CHORDC1", "CHRAC1", "CHTF18", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "CNP", "COA7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCPS", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENPP1", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC6L", "ERH", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM129B", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGH", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLPH3", "GOLPH3L", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPCAL4", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPDH2", "INF2", "INTS1", "INTS11", "INTS12", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISYNA1", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRPPRC", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LYAR", "LYPLA1", "LYPLA2", "MACF1", "MAD2L1", "MAGED2", "MAN1A1", "MAN2B1", "MAP1A", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED21", "METAP2", "METTL13", "MFN2", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL33", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL55", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCEH1", "NCL", "NCOA5", "NDRG1", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAF1", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEK9", "NELFE", "NENF", "NF1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXNAD1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIK3C3", "PIK3R4", "PIN1", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM2", "PUM3", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDX", "RECQL", "REL", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNF114", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF4", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDAD1", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3B1", "SF3B3", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMU1", "SMYD3", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "SYVN1", "TAB1", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TEX10", "TFAM", "TFCP2", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT1L", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4B", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN7", "UCHL5", "UFD1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VPS11", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZCRB1", "ZDHHC13", "ZFR", "ZFYVE16", "ZNF280C", "ZNF281", "ZNF346", "ZNF512", "ZNF512B", "ZNF638", "ZNF830", "ZPR1", "ZRANB2"], "leading_proteins": ["ACADM", "ACBD3", "AFDN", "AFG3L2", "AHNAK", "AHSA1", "AIFM1", "AKAP1", "ALDH1A2", "ALDH1B1", "ANAPC7", "ANK3", "ANKRD17", "ANXA4", "AP1B1", "AP3S1", "APBB1", "ARCN1", "ARHGEF7", "ASCC1", "ASPH", "ATP2B1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BCL10", "BRD4", "CALU", "CAPZA1", "CASK", "CBX1", "CBX5", "CD2AP", "CD47", "CDC16", "CHD4", "CIRBP", "CLUH", "CMAS", "CNNM4", "COLGALT1", "COPG1", "COPZ1", "CPSF7", "CRTAP", "CSK", "CTNNA1", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5D2", "CYP51A1", "DERL1", "DNAJC10", "DNAJC11", "DNAJC8", "DST", "DUSP9", "DVL2", "EFL1", "EFTUD2", "EIF2D", "EIF4B", "EIF4H", "ELOA", "EMC1", "EMD", "EML4", "ENPP1", "EPRS", "ERBIN", "ESF1", "EWSR1", "EXOC7", "FAF2", "FCGRT", "FDPS", "FKBP14", "FKBP5", "FKBP7", "FMR1", "FUBP1", "FUS", "FXR1", "G3BP2", "GAK", "GALNT1", "GALNT2", "GAPVD1", "GFM1", "GOPC", "GRB2", "GRSF1", "GTF2F2", "GUF1", "HDGFL2", "HECTD1", "HGS", "HIF1AN", "HLA-A", "HLA-B", "HLTF", "HMOX2", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPDL", "HNRNPH3", "HNRNPK", "HNRNPLL", "HNRNPR", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HTATSF1", "HUWE1", "IKBKB", "INTS11", "IQGAP2", "KIAA0391", "KLC1", "KLC2", "KLC4", "KMT2A", "LARP4", "LASP1", "LEMD2", "LEMD3", "LMNA", "LMNB2", "MBD3", "METTL13", "MFSD3", "MFSD5", "MGST3", "MIA3", "MID1", "MOGS", "MORF4L1", "MOSPD2", "MPP1", "MPP2", "MRPL14", "MRPS2", "MSH2", "MSH6", "MSTO1", "MTR", "MVK", "MYEF2", "MYO1E", "NAA25", "NAP1L4", "NAPG", "NASP", "NCL", "NEDD4L", "NENF", "NF1", "NOL8", "NOP56", "NPEPPS", "NRDC", "NSD2", "NSFL1C", "NSMCE2", "NSUN2", "NTMT1", "NUB1", "NUCB2", "NUP35", "OCLN", "OGT", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PARN", "PCYOX1", "PDHX", "PDLIM3", "PFDN2", "PFDN6", "PGRMC1", "PIGG", "PIK3C3", "PIN1", "PITPNA", "PPP1R7", "PREB", "PRPF31", "PRPF40A", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PSME2", "PSME3", "PSPC1", "PTK2", "PTK7", "PTPRF", "PWP2", "RAPGEF2", "RASAL2", "RBM10", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM3", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RCN1", "RCN2", "RDX", "REPS1", "RMDN3", "RNF114", "RNF20", "RNF40", "RPRD2", "RPS3", "RPS5", "RSU1", "SEC63", "SET", "SF1", "SF3A1", "SFPQ", "SFSWAP", "SHOC2", "SLC16A1", "SLC25A20", "SLC25A21", "SLC25A26", "SLC33A1", "SLIRP", "SMARCA4", "SMARCA5", "SMC3", "SMYD3", "SND1", "SNX27", "SNX3", "SORBS3", "SPART", "SPEN", "SPNS1", "SPTAN1", "SQLE", "SRPRA", "SRSF1", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF9", "STAM", "STARD3", "STARD7", "STAT1", "STOM", "STX7", "STXBP4", "SUGP1", "SYNCRIP", "SYVN1", "TAF15", "TBC1D15", "TBC1D9B", "THOC1", "TIA1", "TIAL1", "TIMM13", "TIMM8B", "TJP2", "TMTC3", "TRA2B", "TRAPPC4", "TRIM21", "TRIP12", "TRMT61A", "TSPAN6", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTK", "TUBB3", "TUBB4A", "UBE3A", "UBE3C", "UFM1", "UGGT1", "UHRF1", "USP15", "USP39", "USP47", "USP48", "UTP6", "UTRN", "UXT", "VCL", "VPS11", "VPS4B", "VPS51", "WDR75", "WRNIP1", "YTHDC2", "ZADH2", "ZC3H15", "ZCCHC3", "ZCRB1"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3e88d79021b948cd06754303572d5466a35ef008 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a64793ab00e2896251fc9e1c4b886768f13eefecdf3677e40517e3468da727d +size 64837 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e88527f5ea5b3cfc0dc370170187022ec33813eb --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.75 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4cbbb2296420c7ebff566c2f38dd29a670535657 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..60a43dd951cb9ee20b82890f497ce5afd725f26a --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.3098146523417641 0.0797719984717695 0.936418595313444 0.9999836574254888 0.936418595313444 8 P20020 1 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5ebfbf987293a095cd2d7d849ec57e279205b6da --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7A", "ATP7B", "EIF5A", "FASN", "SLIT2"], "leading_proteins": ["ATP2B1"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e279d960bcf486ef125535a3f6c052485e7bbad1 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tetratricopeptide repeat [IPR019734]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..156af5b953066c16860e72ef7b83a703e66d21d3 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2cfd5f432ea0d22dbe8be80939841eaf603c4d62f5ee27878f33368d6baf9387 +size 143547 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8797c5a4ff092b86e53cf844f162d319128be19d --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:793ad844a46097da463f54a8c7b333fe846f777b6bef47c1e70d115c45de8534 +size 67128 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d73f45a3e31561adf00bd1092fdbe02cc79529ce --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 74, + "title": "Average number of proteins per term", + "value": 5.337837837837838 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9cf16a7ca75f6b4290cadc4f8fae1500c816ee5b --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..25a8438a5ef30b454f7cf9a4e270fb21b93878fc --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,15 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Spectrin repeat [IPR002017] 0.6704121361033573 1.5901347370247003 0.1118044374330708 0.9998452479774868 0.684127921053328 9 Q01082,Q13813,Q03001,O15020 4 +Annexin repeat [IPR018502] 0.6325654317404608 1.4008759057112858 0.1612511849723037 0.9999977676512096 0.684127921053328 6 P09525 1 +Leucine-rich repeat, typical subtype [IPR003591] 0.5924527966085353 1.2330195137751478 0.217568483866875 0.9999999869674674 0.684127921053328 12 Q15404,Q15435,Q9UQ13 3 +Tetratricopeptide repeat [IPR019734] 0.356651571131032 1.1519889096148432 0.2493256306797706 0.99999999939268 0.684127921053328 44 Q6PGP7,O15460,O95801,Q6ZXV5,Q07866,Q9H6T3,Q9UJX3,Q9H0B6,A0AVF1,P13674,Q6DKK2,Q13042,Q9BXJ9,Q9Y5Q9,O15294,Q9H3U1,P49321,Q9NSK0,Q13217,Q12797,Q13451 21 +Kinesin light chain repeat [IPR015792] 0.7266235974158475 1.1290915551697314 0.2588592133715295 0.9999999997641408 0.684127921053328 3 Q9H0B6,Q9NSK0 2 +Spectrin/alpha-actinin [IPR018159] 0.4987354353775354 0.7669866562652043 0.4430894492005366 1.0 0.7997224205082856 11 Q01082,Q13813,Q03001,O15020 4 +HEAT repeat [IPR000357] 0.4682895114173943 0.6436273468951854 0.5198171125570199 1.0 0.8533462598345551 6 P30154,Q6PJG6 2 +Pentatricopeptide repeat [IPR002885] 0.5396123767426164 0.4583233774462218 0.6467201312455397 1.0 0.9371695280728468 3 P42704,Q92552 2 +Leucine-rich repeat [IPR001611] 0.4097322047952809 0.3966005642186014 0.6916620364241983 1.0 0.9371695280728468 21 Q15404,Q15435,Q9UQ13 3 +Mitochondrial substrate/solute carrier [IPR018108] 0.3897472917618136 0.2969603477818175 0.7664967821573376 1.0 0.9492947162431132 20 O43772,Q9BQT8,Q70HW3 3 +Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547] 0.6240652617267031 0.1926520887338498 0.8472314480750454 1.0 0.9568381915368874 2 Q9H270 1 +PFTB repeat [IPR001330] 0.6091094493541872 0.168326444819769 0.8663264707158305 1.0 0.9568381915368874 2 P53611 1 +Hexapeptide repeat [IPR001451] 0.3699421965317899 0.090017379139247 0.9282734043395172 1.0 0.9725281586880842 3 Q13144,Q96IJ6 2 +Armadillo [IPR000225] 0.2967778188143797 0.0061118723871285 0.9951234617452333 1.0 0.9951234617452333 16 P25054,P52292,O60716,O60763 4 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b9941068a66bc70d357c0077879b69ffcc0adaf6 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "PQ-loop repeat [IPR006603]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD13A", "ANKRD17", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "APC", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ASPH", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CD320", "CDC16", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "CNOT10", "COA7", "COLEC12", "COPA", "COPB2", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GRWD1", "GTF2I", "GTF3C3", "HCFC1", "HECTD1", "HUWE1", "IGF2R", "ILK", "IPO4", "IPO5", "JUP", "KAT7", "KDELC2", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRPPRC", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "MACF1", "MAP1B", "MAP4", "MKI67", "MPDU1", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "POLR2A", "PPID", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD3", "PUM1", "PUM2", "PUM3", "PWP1", "PWP2", "RABGGTA", "RABGGTB", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP5", "RCC1", "RCC2", "RNH1", "RPAP3", "RPTOR", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SGTA", "SHOC2", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS11", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "XAB2", "XPO1", "YTHDC2", "ZDHHC13"], "leading_proteins": ["ANAPC7", "ANXA4", "APC", "ASPH", "BRAT1", "CDC16", "CTNND1", "DNAJC3", "DST", "EIF2B5", "FKBP5", "GMPPA", "GTF3C3", "KLC1", "KLC2", "KLC4", "KPNA2", "LRPPRC", "MRPS27", "NAA15", "NASP", "OGT", "P4HA1", "P4HA2", "PPP1R7", "PPP2R1B", "RABGGTB", "RPAP3", "RSU1", "SHOC2", "SLC25A20", "SLC25A21", "SLC25A26", "SPTAN1", 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1 9 2.1015665621192263 0.0355912615386906 1.9563106796116505 8.939320388349515 0.9100937072347148 0.3197058737817761 1.2933864561055997 1.001798152387997 1.0059424935454593 0.2746313949658078 0.0937235599037543 0.0161297090986061 0.0846217526668656 0.255405515221392 +Negative regulation of mrna 3 end processing 3 6 2.0861594418534497 0.0369641827512308 2.9635922330097086 6.468446601941747 0.2166539590331943 0.6001953854826652 1.905825180895102 1.086758123053347 0.7594435552730779 0.2898575846163733 1.0 1.0 0.1995721086637891 0.0078003581692789 +Response to cold 3 10 2.0801570374783247 0.0375111314065532 3.2063106796116503 11.762135922330096 -0.180809603809966 0.5021052609627927 1.8403933150181828 1.3712453771800803 0.958615312577382 0.2831803681488195 1.0 0.2636091346473535 0.0065049624434193 0.0623633603808868 +Leukocyte mediated immunity 9 43 2.0748038781221263 0.038004715022861 10.5873786407767 48.439320388349515 0.1870678619616392 0.6863169751438244 4.6094706140801085 4.980906020077718 0.7184127170430001 0.2997698808543378 0.1760534030430948 0.1946802572685101 0.1786437467168821 0.2261702049528859 +Regulation of dna methylation 3 9 2.06574475967375 0.0388525865292959 1.9927184466019416 8.83252427184466 0.7131887814592797 0.4532119966636778 1.6480189308548123 1.5386952097280358 0.8551167704417201 0.3087271346477002 0.0802348466038066 0.1543818096433915 0.0635022977163126 0.0080495273899022 +Fc receptor signaling pathway 2 6 2.045980805995253 0.0407582591467072 2.434567901234568 6.303703703703704 -0.1887920783238133 0.513488227334657 1.740949116326016 2.1335905194767566 0.9996183728939608 0.3078132725522039 0.1541506060207377 0.2851312580635185 0.0494008625159685 0.229933672353323 +Protein destabilization 2 8 2.044552743057856 0.0408989725250936 2.7354368932038833 10.45631067961165 0.1966664591237481 0.5900816170601417 2.0949329885702923 1.5455963063857037 0.7736089205355409 0.2850412838600868 0.0140700862732742 0.0507931717892238 0.0608575356821196 0.2698089294696847 +Regulation of rna splicing 43 78 2.0139929477323246 0.0440102739131835 27.91990291262136 86.5121359223301 0.1323494025528259 0.5572910110956871 9.72639747067558 5.208502039558804 1.4178017247437722 0.381677869420044 0.4847391385004878 0.1443148752822858 2.302669193919361e-05 5.606643627505319e-09 +Interferon gamma production 3 7 2.013345842044808 0.0440782588467865 2.3009708737864076 7.305825242718447 0.1518987527079034 0.5748478311166311 1.3659162539277057 0.7298523913430803 0.8243564394613923 0.2886113119342636 1.0 1.0 0.0608575356821196 0.1046016200934935 +Negative regulation of rna catabolic process 14 32 2.002150993788408 0.0452684945000545 11.186893203883496 32.42718446601942 0.419853700893663 0.5432159718224696 4.924332595678975 2.3133296381008863 1.0980554146273172 0.3596399931743501 1.0 0.0191373699896123 0.0004948612164357 0.0004436609938217 +Negative regulation of innate immune response 4 10 1.9955225107208407 0.0459859215059983 3.6601941747572817 12.856796116504857 -0.0157790405310476 0.590907781650552 2.2535986240705483 2.153429738357667 0.8093295300651749 0.2900978386224676 0.0155575631698287 0.0558103535730672 0.0691213376044611 0.0398975682783081 +Peptidyl proline hydroxylation to 4 hydroxy l proline 1 5 1.9844625468034816 0.047204299346939 1.91747572815534 4.978155339805825 0.4438057662566078 0.4820538119388955 1.3267177679592008 0.5324503670252024 0.940328511916904 0.3132987011445886 1.0 0.0666860823201616 0.0115035556388008 0.0424606815374328 +Positive regulation of binding 11 50 1.9820716435125645 0.0474712227347466 11.820388349514564 51.97330097087379 -0.0367767487556686 0.6444735417234735 5.2912064662609914 4.441831793991704 0.7729739616321648 0.3071478065657121 0.0305051812830626 0.1558849497402792 0.2525848733650708 0.03916050194843 +Mitochondrial electron transport cytochrome c to oxygen 2 7 1.981988324551209 0.0474805474028241 2.6189320388349513 6.021844660194175 0.7576771538928655 0.3133819177040797 1.4641113893518565 0.9306060741204804 1.2097595052740109 0.2966582872605096 1.0 0.1116045715736199 0.256848998879423 0.0183139901045195 +Negative regulation of immune system process 10 39 1.9757827749824344 0.0481793851395764 10.262135922330096 46.91019417475728 0.2444799455656694 0.6277319776406994 4.757132947946456 7.065174604728879 0.8023664740567815 0.321929768279026 0.2080546526177427 0.2407998196724879 0.0616392517605005 0.1398083453673571 +Somatic diversification of immune receptors via somatic mutation 0 5 1.9710938310394783 0.0487131442296879 1.5970873786407769 5.842233009708738 0.4117560170730587 0.426937860883498 1.54944125918537 0.7832362934246239 1.055920551903701 0.3055647908581022 0.0573151884822011 0.1116045715736199 0.256848998879423 0.451869757084416 +Histone h2b ubiquitination 2 7 1.9667565279177053 0.049211286517365 2.737864077669903 6.37621359223301 -0.1136080908874751 0.5691730594317124 1.6602793369402489 1.2154815390840317 0.8187558288131649 0.2865910021674811 1.0 0.1203280145079081 0.0388074443523606 0.022960782690956 +Negative regulation of response to external stimulus 9 40 1.9611399027200516 0.0498627050679518 9.381067961165048 47.019417475728154 0.8063071074275461 0.4700507256615295 4.127569023520378 6.3589713134688575 0.9364755672970396 0.3491987458588393 0.0511928730161325 0.0871808848826675 0.1254784047373908 0.3249900544250382 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e8adbc8bcaf5160def3efb65e474c8fd60ae6c99 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 6379, + "title": "Average number of proteins per term", + "value": 18.28750587866437 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..601255bb88d467098ce313b4c8c43aa1ebd5c3ef --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..895a84ffe3a93ab90a9fc81d2edc5eea8821d54c --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1624 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Negative regulation of mrna metabolic process 0.6414318416954109 3.8515577398649423 0.0001173688483309 0.527037806910381 0.7486958835028946 44 A2RRP1,Q99729,Q92804,Q13242,P49137,P61978,P98175,Q08170,O00267,Q6PJT7,Q06787,P67809,P38159,Q07021,O75150,Q5VTR2,Q9Y2W1,P35637,Q9H074,Q13247,P11940,Q14011,P22626,O60506 24 +Terpenoid biosynthetic process 0.924375048320607 2.6877339677656273 0.0071938684977586 1.0 1.0 6 P48449,O94788 2 +Response to l glutamate 0.9662603986195164 2.42879718834215 0.0151490038753978 1.0 1.0 4 O95831 1 +Retinoic acid metabolic process 0.9596957007883752 2.403759149695256 0.0162274606888055 1.0 1.0 4 O94788 1 +Regulation of t cell mediated immunity 0.8485996053552546 2.370089839191961 0.0177837634540936 1.0 1.0 6 Q9NUQ9,O15400,P04439 3 +Fatty acid transmembrane transport 0.8195964373656724 2.2453036855537927 0.0247486436057553 1.0 1.0 6 O43772,P31751 2 +Regulation of response to biotic stimulus 0.4821219788484607 2.2404528162180406 0.0250615407072529 1.0 1.0 56 Q9NZ08,Q9UIV1,P01889,O14920,O43657,Q9Y4E8,P19474,O75179,P04439,Q96PK6,Q8WXF1 11 +Positive regulation of t cell mediated cytotoxicity 0.9112244897959216 2.2167262348703103 0.0266418048996301 1.0 1.0 4 P04439,O15400,Q9NUQ9 3 +Regulation of t cell mediated cytotoxicity 0.9112244897959216 2.2167262348703103 0.0266418048996301 1.0 1.0 4 P04439,O15400,Q9NUQ9 3 +Regulation of leukocyte mediated cytotoxicity 0.8072317515090409 2.1915635669539943 0.0284110350716659 1.0 1.0 6 Q9NUQ9,O15400,P04439 3 +Positive regulation of cell killing 0.8072317515090409 2.1915635669539943 0.0284110350716659 1.0 1.0 6 Q9NUQ9,O15400,P04439 3 +Peptidyl proline hydroxylation 0.8039849317074622 2.1861489355991353 0.0288047107869495 1.0 1.0 7 P13674,Q32P28 2 +Formation of extrachromosomal circular dna 0.9021922349042412 2.181456500940989 0.029149668484147 1.0 1.0 4 O60934,Q9UQ84 2 +Regulation of protein binding 0.4615536306203107 2.175980813501368 0.0295566952475878 1.0 1.0 47 Q96EV8,P35269,Q13526,Q9BUN8,P10586,P62942,P19474,Q92797,Q08379,Q9Y4G8 10 +Positive regulation of t cell mediated immunity 0.8689591882255479 2.174169324081978 0.029692421234281 1.0 1.0 5 Q9NUQ9,O15400,P04439 3 +Response to mineralocorticoid 0.7995507789755427 2.1580180055295655 0.0309264319187669 1.0 1.0 6 O95831 1 +T cell mediated cytotoxicity 0.7985906463121248 2.1538160583577217 0.0312545998674385 1.0 1.0 6 Q9NUQ9,O15400,P04439 3 +Regulation of cell killing 0.7860866186753519 2.106892476855268 0.0351269008853178 1.0 1.0 7 Q9NUQ9,O15400,P04439 3 +Response to increased oxygen levels 0.7801070370503476 2.1015665621192263 0.0355912615386906 1.0 1.0 9 P00846 1 +Diterpenoid biosynthetic process 0.9807578215618216 2.098901655042551 0.0358255709398618 1.0 1.0 3 O94788 1 +Regulation of histone h2b ubiquitination 0.8797428814077856 2.0932366076065563 0.0363280383741444 1.0 1.0 4 Q5VTR2,Q9NW82 2 +Negative regulation of mrna 3 end processing 0.783191384390097 2.0861594418534497 0.0369641827512308 1.0 1.0 6 O75150,Q5VTR2,Q6PJT7 3 +Response to cold 0.7724827014301732 2.0801570374783247 0.0375111314065532 1.0 1.0 10 P11310,P00403,Q14011 3 +Leukocyte mediated immunity 0.4622712291433903 2.0748038781221263 0.038004715022861 1.0 1.0 43 O95999,Q07021,P01889,Q9NUQ9,O60934,Q9UQ84,P10909,P04439,O15400 9 +Regulation of dna methylation 0.7722505282546107 2.06574475967375 0.0388525865292959 1.0 1.0 9 Q8NB78,Q96TA1,Q03164 3 +Fc receptor signaling pathway 0.7740989029393156 2.045980805995253 0.0407582591467072 1.0 1.0 6 O14920,Q05397 2 +Protein destabilization 0.7700606533807143 2.0445527430578556 0.0408989725250936 1.0 1.0 8 Q9BUN8,P19474 2 +Antigen processing and presentation of exogenous peptide antigen 0.8644254853904133 2.03259392573553 0.0420935657020868 1.0 1.0 4 P04439,O14920 2 +Amyloid precursor protein biosynthetic process 0.8636054421768775 2.029337204142847 0.0424239563669672 1.0 1.0 4 Q9NQX7,P35610,Q96IZ0 3 +Regulation of rna splicing 0.4910464641446264 2.0139929477323246 0.0440102739131835 1.0 1.0 78 Q12872,Q9Y5S9,O75312,P52756,Q09161,Q96E39,Q07955,P31483,Q96QD8,Q13242,P61978,Q13573,P98175,Q08170,P51114,P62995,P84103,Q8IXT5,Q09666,Q15637,P19338,Q06787,Q13243,Q16629,P38159,Q07021,Q9Y2W1,P98179,Q12849,P35637,P31942,P51116,P55795,Q8WVV9,Q96PU8,Q07666,Q13247,Q14320,Q9BWF3,Q5BKZ1,Q14011,P22626,P52597 43 +Interferon gamma production 0.7651540729279879 2.013345842044808 0.0440782588467865 1.0 1.0 7 Q9NUQ9,Q08722,P04439 3 +Negative regulation of rna catabolic process 0.5998213585808253 2.002150993788408 0.0452684945000545 1.0 1.0 32 P98175,A2RRP1,Q14011,Q99729,Q9Y2W1,Q92804,Q9GZT3,P35637,P11940,Q06787,Q9H074,P67809,P49137,Q08J23 14 +Negative regulation of innate immune response 0.7542240833486069 1.9955225107208407 0.0459859215059983 1.0 1.0 10 P04439,Q9Y4E8,P19474,Q9UIV1 4 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.8224835839494959 1.9844625468034816 0.047204299346939 1.0 1.0 5 P13674 1 +Positive regulation of binding 0.4466406034991352 1.9820716435125645 0.0474712227347466 1.0 1.0 50 O00330,Q13526,Q06787,Q9BUN8,Q96TA1,Q09161,P62942,P19474,P18074,Q9Y4G8,Q96HY6 11 +Mitochondrial electron transport cytochrome c to oxygen 0.758182360976581 1.981988324551209 0.0474805474028241 1.0 1.0 7 P00403,Q7KZN9 2 +Negative regulation of immune system process 0.5094146343636743 1.9757827749824344 0.0481793851395764 1.0 1.0 39 P28070,Q9UIV1,Q92990,P01889,Q08722,Q9Y4E8,P19474,Q96IZ0,P04439,Q5JRA6 10 +Histone h2b ubiquitination 0.7548038092671123 1.9667565279177055 0.049211286517365 1.0 1.0 7 Q5VTR2,Q9NW82 2 +Negative regulation of response to external stimulus 0.4939014435403476 1.9611399027200511 0.0498627050679518 1.0 1.0 40 P28070,Q9UIV1,P04439,P01889,O43657,Q9Y4E8,P19474,P80303,Q9UMX5 9 +Mitochondrion distribution 0.8154231473930376 1.9553239181141395 0.0505448498375198 1.0 1.0 5 O75153 1 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.8408895133461209 1.9387233411041396 0.0525350349192792 1.0 1.0 4 O43657 1 +Regulation of innate immune response 0.5181429751654912 1.937404649395983 0.0526958987469297 1.0 1.0 38 Q9NZ08,Q9UIV1,P01889,O14920,Q9Y4E8,P19474,P04439,Q96PK6 8 +I kappab phosphorylation 0.8400873431591229 1.9355095984334136 0.0529277919589725 1.0 1.0 4 O14920 1 +Antigen processing and presentation of exogenous antigen 0.7476982367332483 1.9346466145163888 0.053033675640576 1.0 1.0 7 P04439,O14920 2 +Phosphatidic acid metabolic process 0.8093412064357396 1.9301581296579609 0.0535872477122558 1.0 1.0 5 Q9NPH0 1 +Protein hydroxylation 0.7278848764541247 1.918345241040334 0.0550672494748429 1.0 1.0 13 P13674,Q92791,Q96AY3,O15460,Q32P28 5 +Terpenoid metabolic process 0.7094627485838799 1.9181395086370017 0.0550933239809421 1.0 1.0 17 P48449,Q9BY49,O94788 3 +Amyloid fibril formation 0.741876804906178 1.91617053086495 0.0553433930570896 1.0 1.0 8 P10909,P62942,O15212 3 +Mrna splice site selection 0.7214521248477301 1.9064860563541048 0.0565871730572449 1.0 1.0 14 Q12874,Q13247,Q07955,Q15637,Q9NQ29,Q13242,Q13243,Q15459 8 +Regulation of membrane protein ectodomain proteolysis 0.8309353481211328 1.8987784217044648 0.0575936154857443 1.0 1.0 4 O43847 1 +Complement activation 0.8304919352960582 1.8969957715382135 0.0578284961725761 1.0 1.0 4 P10909 1 +Negative regulation of mrna processing 0.6868702006406345 1.89178424486652 0.0585197333095739 1.0 1.0 20 Q12872,P98175,P38159,Q07021,Q08170,O75150,Q5VTR2,Q13247,O00267,Q6PJT7,Q13242,P22626,P61978 13 +Dendrite extension 0.7983486835245159 1.8845221954451337 0.0594943754322421 1.0 1.0 5 Q9Y263 1 +Production of sirna involved in rna interference 0.8268474961102973 1.8823335664727192 0.0597907397353023 1.0 1.0 4 Q9UPY3 1 +Protein lipid complex subunit organization 0.8245838602223529 1.8732172129194524 0.0610383963478899 1.0 1.0 4 Q8WTV0 1 +Activation of immune response 0.427418940213947 1.866668131505506 0.0619479467257477 1.0 1.0 45 P61088,Q15233,P12956,O14920,Q13177,P10909,P43243,Q8WXF1,P46379,Q9UJZ1,Q07021,Q08722,Q96IZ0,P23246,O95999,Q9NUD5,Q07666,P41240,P04439,Q96PK6,Q05397 21 +Vasculogenesis 0.7310844826285036 1.8665825889163183 0.061959900868612 1.0 1.0 8 Q9NWT6,Q92990,Q4VCS5,Q12965,Q9Y4G8 5 +Isoprenoid biosynthetic process 0.7249569853795385 1.8583868873221217 0.0631140930371663 1.0 1.0 10 P48449,O94788 2 +Apoptotic dna fragmentation 0.817567462364897 1.844915052256228 0.0650498967006334 1.0 1.0 4 O95831 1 +Modified amino acid transport 0.9119085132299356 1.841160107438958 0.065598099430393 1.0 1.0 3 O43772 1 +Myotube cell development 0.8164186140063183 1.8402745129478324 0.0657279452545027 1.0 1.0 4 Q9H7B4 1 +Regulation of mrna splicing via spliceosome 0.4413133403315182 1.8378869957962791 0.0660790587284541 1.0 1.0 56 Q12872,Q9Y5S9,P52756,Q09161,Q96E39,P31483,Q13242,Q13573,P61978,P98175,Q08170,P51114,P62995,P84103,Q15637,P19338,Q06787,Q16629,P38159,Q07021,Q9Y2W1,P98179,P51116,Q96PU8,Q13247,Q9BWF3,Q14011,P22626 28 +Detection of external biotic stimulus 0.9109146548792976 1.8373999190232135 0.0661508787786799 1.0 1.0 3 P04439,Q8WTV0 2 +Positive regulation of mononuclear cell migration 0.7217911759928113 1.8236991410550147 0.0681975687918927 1.0 1.0 8 Q8NHP6,Q08722,Q07021 3 +Protein polyubiquitination 0.4287897868722397 1.8182954933167612 0.0690189812448975 1.0 1.0 49 Q9Y508,Q86TM6,Q15386,P61088,Q13042,O75150,Q5VTR2,P55786,Q9UIQ6,P19474,Q7Z7E8,Q9Y263,Q13951,P61086 14 +Regulation of bone mineralization 0.7808088553854831 1.8113126460804307 0.0700924692325943 1.0 1.0 5 P20020 1 +Long chain fatty acid transport 0.7109731605713748 1.804598412664494 0.0711375466582651 1.0 1.0 11 O43772,P31751 2 +Protein ufmylation 0.7768585284629771 1.794759815868867 0.0726919757253283 1.0 1.0 5 Q96JB5,Q9GZZ9,Q96HY6 3 +Convergent extension 0.8984879849793566 1.7902974879514288 0.0734060999012231 1.0 1.0 3 Q13308 1 +Negative regulation of supramolecular fiber organization 0.4195419655857917 1.786803398644547 0.0739692698651095 1.0 1.0 45 P46821,P35241,Q9NUQ9,P04350,Q01082,Q9UHV9,O15212,Q13177,Q7Z460,P35611,P16949,Q13813,O15344,O15020,P25054,P10909,P52907,Q14155 18 +Regulation of amyloid beta clearance 0.7739308528411881 1.7824772285992236 0.0746714414100653 1.0 1.0 5 Q16850,P10909 2 +Formation of translation preinitiation complex 0.7127160068936128 1.7816630807453362 0.0748041908813799 1.0 1.0 8 Q15056,P55010,P23588 3 +Positive regulation of neutrophil migration 0.7718667224687547 1.77380995390942 0.0760945910928081 1.0 1.0 5 Q8NHP6,Q07021,Q8NE86 3 +Positive regulation of granulocyte chemotaxis 0.7718667224687547 1.77380995390942 0.0760945910928081 1.0 1.0 5 Q8NHP6,Q07021,Q8NE86 3 +T cell mediated immunity 0.7079673324742201 1.7678169853438626 0.0770915044141022 1.0 1.0 9 Q9NUQ9,O15400,P04439 3 +Negative regulation of response to biotic stimulus 0.6804430437312832 1.767675461786642 0.0771151744864258 1.0 1.0 17 Q9UIV1,P01889,O43657,Q9Y4E8,P19474,P04439 6 +Positive regulation of viral life cycle 0.7107680012346055 1.76616929878938 0.0773674500845749 1.0 1.0 7 Q06787,P19474 2 +Humoral immune response mediated by circulating immunoglobulin 0.8898333900034073 1.7574005960984744 0.0788495517976066 1.0 1.0 3 P10909,Q9UQ84 2 +Regulation of skeletal muscle tissue development 0.7945657528559402 1.7516726995882528 0.0798301038240882 1.0 1.0 4 O94966 1 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.8881332879972865 1.7509297712718734 0.0799580078580071 1.0 1.0 3 P04439,O14920 2 +Cochlea development 0.7075547667354327 1.7469248725240658 0.080650370738752 1.0 1.0 6 Q13308 1 +Meiotic cell cycle 0.4290101721657104 1.744188989626983 0.0811261406049745 1.0 1.0 54 Q8N2A8,P24941,Q92791,Q9BSJ2,Q92878,Q96KQ7,Q12768,O60934,Q9UQ84,Q9UH99,Q5VUA4,Q08379,Q08J23,P46379 14 +Microtubule organizing center localization 0.7004953025140512 1.742447175197937 0.0814302272146594 1.0 1.0 10 Q9UH99,Q8TD16,Q13257,O94901,P33176 5 +Glyoxylate metabolic process 0.8838887549400194 1.7347624936719983 0.0827828820073128 1.0 1.0 3 P48735 1 +Cellular response to mineralocorticoid stimulus 0.8824824987226956 1.7294023868663848 0.083737103132552 1.0 1.0 3 O95831 1 +Membrane protein ectodomain proteolysis 0.6983930737450958 1.7227508381844563 0.0849335925360568 1.0 1.0 9 Q9UKS6,P38159,Q9NZ08,O43847 4 +Regulation of cellular response to insulin stimulus 0.6865658951419088 1.7153579665434515 0.0862796168902171 1.0 1.0 13 P20020,Q9BZF1,Q12965,O60763,Q9HCD5,Q9H1E3 6 +Negative regulation of cellular response to insulin stimulus 0.7576280141696256 1.713855752130958 0.0865552211683993 1.0 1.0 5 Q9HCD5 1 +Regulation of dna replication 0.4167861639982496 1.711978835482854 0.0869005688672104 1.0 1.0 48 Q96S55,P24941,P35250,Q9UJZ1,Q9NRG0,Q7Z5K2,O95785,Q96KQ7,O60934,Q9NRF9,Q9UNS1,Q29RF7,O75179,P51530,Q9H1E3,Q9BRT9 16 +Organic cation transport 0.7566315376051042 1.7096493498320735 0.0873307341118243 1.0 1.0 5 O43772,Q96QD8 2 +Cellular response to interleukin 1 0.6909677327364072 1.7082786391403733 0.0875846528958261 1.0 1.0 11 Q08722,P38159,O14920 3 +Intermediate filament based process 0.6904992844538068 1.7060142633781823 0.0880054239837115 1.0 1.0 11 Q16352,P08670,Q03001 3 +Positive regulation of glycoprotein metabolic process 0.6970089123952451 1.7027529725422634 0.0886143069592768 1.0 1.0 7 P35610,Q08379,Q96IZ0 3 +Positive regulation of leukocyte migration 0.6760109763423806 1.698957893411406 0.0893271175417016 1.0 1.0 15 Q07021,Q8NHP6,Q08722,Q8NE86,Q5JRA6,O00429,Q05397 7 +Negative regulation of mrna catabolic process 0.617813332803604 1.6977713547523496 0.0895509243501666 1.0 1.0 25 P98175,A2RRP1,Q14011,Q99729,Q9Y2W1,Q92804,P35637,P11940,Q06787,Q9H074,P49137,P67809 12 +Positive regulation of membrane protein ectodomain proteolysis 0.8734460308199956 1.6949158676415397 0.090091381948971 1.0 1.0 3 O43847 1 +Microtubule anchoring 0.6875025067362215 1.6804109241558554 0.0928773920518124 1.0 1.0 10 O95684 1 +Glycoprotein biosynthetic process 0.4103375039385536 1.6772575825764238 0.0934921232917498 1.0 1.0 46 Q8TCJ2,Q13724,Q96IZ0,Q9HC07,P33908,Q08379,Q9NQX7,O60701,Q96AA3,P35610,Q9NYU2 11 +Regulation of amyloid fibril formation 0.7486494181982033 1.6759064256886391 0.0937565229023449 1.0 1.0 5 P10909,O15212 2 +Negative regulation of amyloid fibril formation 0.7486494181982033 1.6759064256886391 0.0937565229023449 1.0 1.0 5 P10909,O15212 2 +Pancreas development 0.6862709525526292 1.674515183292626 0.0940293929348146 1.0 1.0 10 O94788 1 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.6881326228943165 1.6742733042143962 0.0940768985792659 1.0 1.0 9 O43657,Q9Y4E8,Q07021,O75179 4 +Reticulophagy 0.7744344160302838 1.669526376725489 0.0950131074816686 1.0 1.0 4 Q9GZZ9,Q96HY6 2 +Protein polyufmylation 0.7744344160302838 1.669526376725489 0.0950131074816686 1.0 1.0 4 Q96HY6,Q9GZZ9 2 +Secondary alcohol metabolic process 0.4604345280388183 1.668189615749037 0.0952780916440376 1.0 1.0 40 Q15392,Q15800,Q16850,O75874,Q14534,P48449,P48735,O75845,O43837,P35610,Q8WTV0 11 +Response to oxygen levels 0.4317363458282326 1.6674913061171903 0.0954167517121911 1.0 1.0 61 Q8N511,P00846,P55786,O95831,P30519,P05026 6 +Negative regulation by host of viral transcription 0.7731771370601377 1.6643805406396006 0.0960364063096552 1.0 1.0 4 Q9H1E3 1 +Cellular response to corticosteroid stimulus 0.681839750249476 1.6640855695056371 0.0960953304184055 1.0 1.0 11 Q9H7B4,O95831 2 +Isocitrate metabolic process 0.7442971696651886 1.657472838479427 0.0974239158659264 1.0 1.0 5 O75874,P48735 2 +Axon ensheathment in central nervous system 0.8633117987079306 1.6561552404260695 0.0976903849139518 1.0 1.0 3 P10909,P18074 2 +Positive regulation of amyloid precursor protein biosynthetic process 0.8633117987079297 1.656155240426065 0.0976903849139527 1.0 1.0 3 P35610,Q96IZ0 2 +Collagen fibril organization 0.6852014678884509 1.653305212993172 0.0982687625892833 1.0 1.0 8 P13674,Q92791,Q8NBJ5,Q96AY3,P21359 5 +Cholesterol storage 0.8621177379929128 1.6515826775082902 0.0986196537067471 1.0 1.0 3 Q8WTV0 1 +Regulation of bicellular tight junction assembly 0.685830075294262 1.64752578708247 0.0994500203142878 1.0 1.0 6 O14920 1 +Positive regulation of leukocyte chemotaxis 0.6757818156030582 1.6471932440286152 0.099518332031401 1.0 1.0 12 Q8NHP6,Q05397,Q07021,Q8NE86 4 +Intracellular receptor signaling pathway 0.4206884633876676 1.6448271138281323 0.100005469015159 1.0 1.0 55 Q07021,P42785,O94788,O43657,Q9Y4E8,Q96RT1,O75179,Q9GZZ9,Q96HY6 9 +Negative regulation of mrna splicing via spliceosome 0.6681009376118103 1.6399440025960537 0.1010168105857438 1.0 1.0 14 P38159,Q12872,P98175,Q07021,Q08170,Q13247,Q13242,P22626,P61978 9 +Protein localization to cytoplasmic stress granule 0.6828797213709912 1.6372943590480071 0.1015689790177414 1.0 1.0 7 Q9NPI6,P67809 2 +Adaptive immune response 0.4689510046022613 1.6329207995256825 0.102485655010456 1.0 1.0 39 Q9NZ08,Q07021,P01889,Q9NUQ9,O60934,Q9UQ84,P10909,P04439,O15400 9 +Quaternary ammonium group transport 0.8559106561006994 1.627794952857496 0.1035683710928982 1.0 1.0 3 O43772 1 +Meiotic spindle organization 0.6815104490222794 1.6276694694216574 0.1035949901219353 1.0 1.0 6 Q08379 1 +Dna catabolic process 0.6808985318611309 1.624854269516234 0.1041936142540416 1.0 1.0 6 O95831 1 +Regulation of dendrite extension 0.8548263158769602 1.6236363251500594 0.1044534480360228 1.0 1.0 3 Q9Y263 1 +Positive regulation of actin cytoskeleton reorganization 0.7362633881766223 1.6233835694627612 0.1045074348448924 1.0 1.0 5 Q9UQB8 1 +Cellular response to reactive nitrogen species 0.6804315976304054 1.6227056918742078 0.1046523340648299 1.0 1.0 6 O95831 1 +Response to nitric oxide 0.6804315976304054 1.6227056918742078 0.1046523340648299 1.0 1.0 6 O95831 1 +Positive regulation of protein tyrosine kinase activity 0.7342114478203442 1.6146640153633238 0.1063834742671159 1.0 1.0 5 Q13432,Q15334,O14641 3 +Negative regulation of microtubule polymerization 0.677471178597614 1.6090756738789644 0.1075997956925101 1.0 1.0 6 P04350,P16949 2 +Regulation of systemic arterial blood pressure 0.675588353797197 1.6081580779575548 0.107800562023071 1.0 1.0 8 P42785 1 +Regulation of lipid catabolic process 0.6754508885508635 1.599766466022323 0.1096504006463723 1.0 1.0 6 O75874,Q8WTV0 2 +Mitochondrial fission 0.6675893059541924 1.594808068423935 0.1107551622332629 1.0 1.0 11 Q8TB36,Q9NUQ9,Q8NE86,P11233,Q9UDX5,O00429 6 +Glycoprotein catabolic process 0.8467867763763036 1.5927763238520016 0.1112103783226938 1.0 1.0 3 Q8TCJ2 1 +Membrane protein proteolysis 0.6640062237775555 1.589192114785285 0.1120170261532513 1.0 1.0 12 Q9UKS6,Q9NZ08,Q9H300,O43847 4 +Peptidyl lysine hydroxylation 0.7547145018768044 1.5886240520778498 0.1121452946928784 1.0 1.0 4 Q92791,Q96AY3 2 +Amyloid precursor protein metabolic process 0.6193469564046363 1.5856386720719395 0.112821298396043 1.0 1.0 22 Q15392,Q13526,O75298,P62942,Q96IZ0,Q9NQX7,P10909,P35610 8 +Positive regulation of interferon gamma production 0.7534790748808614 1.5835426687960368 0.113297829375647 1.0 1.0 4 Q9NUQ9 1 +Fatty acid transport 0.6569476354090287 1.5835397730715706 0.1132984888201735 1.0 1.0 14 O43772,P31751,P09455 3 +Leukocyte mediated cytotoxicity 0.6644742789296968 1.5796210674522302 0.1141936716479377 1.0 1.0 11 Q9NUQ9,O15400,P04439 3 +Mrna methylation 0.7227700166002877 1.565954741223382 0.1173592130082339 1.0 1.0 5 Q96FX7 1 +Lymphocyte mediated immunity 0.5465288209590047 1.565522202287997 0.1174605156534929 1.0 1.0 31 Q07021,P01889,Q9NUQ9,O60934,Q9UQ84,P10909,P04439,O15400 8 +Cell death in response to hydrogen peroxide 0.6644900059185987 1.5619068989449338 0.1183099230110522 1.0 1.0 9 Q99720 1 +Centriole assembly 0.6636023152877011 1.5474802769180571 0.1217474768028734 1.0 1.0 7 P24941,Q9C0F1,P06748,O43633,O75351,Q96PK6 6 +Definitive hemopoiesis 0.8347745001117068 1.5465845367577715 0.1219634608245585 1.0 1.0 3 Q96JB5 1 +Regulation of endothelial cell development 0.7180554974134887 1.545841553011596 0.1221428388508703 1.0 1.0 5 P35611,O14920 2 +Negative regulation of defense response to virus 0.7177015398777329 1.5443305450405218 0.1225082764610747 1.0 1.0 5 O43657 1 +Humoral immune response 0.6543700906852775 1.541565671016555 0.1231791730478781 1.0 1.0 12 P10909,P04439,Q9UQ84 3 +Alternative mrna splicing via spliceosome 0.5031078756672493 1.53878794372135 0.1238560741245669 1.0 1.0 35 P51116,Q12872,Q9Y5S9,P98175,P38159,P23246,Q96I25,P52756,P51114,P62995,Q06787,Q9Y2W1,Q07955,P31483,Q13247,Q9BWF3,Q13242 17 +Regulation of response to extracellular stimulus 0.7422872102448264 1.5374468363167375 0.1241839244469287 1.0 1.0 4 Q9UMX5 1 +Dna methylation 0.6358523323168234 1.5330722102336178 0.1252580639480531 1.0 1.0 17 Q8NB78,Q8N2A8,Q96TA1,Q03164 4 +Negative regulation of rna splicing 0.643562022135033 1.5326663621615682 0.1253580812724677 1.0 1.0 15 P38159,Q12872,P98175,Q07021,Q08170,Q13247,Q13242,P22626,P61978 9 +Regulation of mitochondrial fission 0.6601414531581449 1.5312994448601975 0.1256954027052867 1.0 1.0 7 Q9NUQ9,O00429,Q8NE86 3 +Dna replication checkpoint signaling 0.6602075773701479 1.5293375415291022 0.1261807874602192 1.0 1.0 6 Q9Y619,Q9UNS1 2 +Negative regulation of leukocyte mediated immunity 0.7387888607967115 1.5230162394127424 0.1277546426241569 1.0 1.0 4 P01889,P04439 2 +Negative regulation of cell killing 0.8283924744295112 1.5220072261147957 0.1280072700844692 1.0 1.0 3 P04439 1 +Negative regulation of bmp signaling pathway 0.7102244427486522 1.512381968377275 0.1304367193881239 1.0 1.0 5 Q8N0X7,Q05D32,Q9Y2U8 3 +Regulation of neutrophil chemotaxis 0.6541417804739779 1.5032111841291431 0.1327845943747507 1.0 1.0 7 Q8NHP6,Q07021,Q8NE86 3 +Organic acid transport 0.4162045400523359 1.4973582083549806 0.1343000764035351 1.0 1.0 42 O60831,O43772,P23786,Q9Y619,Q96QD8,Q9BQT8,P31751,P09455 8 +Mrna 3 splice site recognition 0.8218293097585936 1.496709343728035 0.1344689039423729 1.0 1.0 3 Q15637,Q15459 2 +Insulin receptor signaling pathway 0.5844439264227869 1.4959501526885142 0.134666645470445 1.0 1.0 25 P22413,P62993,Q8WWQ0,P43490,Q6ZWJ1,Q9BZF1,Q9HCD5,P25054,Q9UQB8,Q9H1E3,P31751 11 +Negative regulation of leukocyte proliferation 0.6527982872678018 1.4949911264661209 0.1349167579902443 1.0 1.0 6 Q96IZ0 1 +Regulation of biomineralization 0.651714415031919 1.49183415844092 0.1357426267366319 1.0 1.0 7 P22413,P20020 2 +Cellular response to insulin stimulus 0.3950581137631536 1.4892089771063404 0.1364323476060249 1.0 1.0 48 P22413,P62993,P20020,P61026,Q8WWQ0,P43490,Q6ZWJ1,Q9BZF1,Q12965,P31751,O60763,Q9HCD5,P25054,Q9UQB8,Q9H1E3,Q13243,Q15043 17 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.8184291057463512 1.4835948464136426 0.1379164374303227 1.0 1.0 3 P01889,P04439 2 +Negative regulation of t cell proliferation 0.7022458219807739 1.4782315981602432 0.1393457990149795 1.0 1.0 5 Q96IZ0 1 +Negative regulation of phosphoprotein phosphatase activity 0.6485072566235895 1.4767912583110034 0.1397316005620423 1.0 1.0 7 P62942,O14920,O75116 3 +Macrophage proliferation 0.7008120178220335 1.4720885717317362 0.1409969611807706 1.0 1.0 5 P10909 1 +Negative regulation of protein dephosphorylation 0.6442374692124251 1.471861559678433 0.1410582658780148 1.0 1.0 10 P62942,O14920,O75116,O43768 4 +Interleukin 1 mediated signaling pathway 0.7002440742937887 1.469654776707079 0.1416552766481404 1.0 1.0 5 O14920 1 +Negative regulation of lymphocyte mediated immunity 0.8116002221873682 1.4572407402261134 0.1450499383633707 1.0 1.0 3 P04439 1 +Response to estradiol 0.6315328747908493 1.4542968914197594 0.1458640119400389 1.0 1.0 14 O94788 1 +Endoplasmic reticulum to cytosol transport 0.6355526727987808 1.448186885034742 0.1475647914428304 1.0 1.0 12 Q9BUN8 1 +Negative regulation of muscle tissue development 0.8064616775422956 1.4373981491704653 0.1506048944044085 1.0 1.0 3 O94966 1 +Negative regulation of muscle organ development 0.8064616775422956 1.4373981491704653 0.1506048944044085 1.0 1.0 3 O94966 1 +Positive regulation of protein binding 0.5934296932476812 1.4365821180786762 0.1508367676371556 1.0 1.0 22 Q13526,Q9BUN8,P62942,P19474,Q9Y4G8 5 +Protein homooligomerization 0.4342460505387158 1.4350909686034643 0.1512611768088638 1.0 1.0 40 Q99720,O94788,Q08379,P35637,Q96CX2 5 +Negative regulation of regulated secretory pathway 0.8055062761556595 1.433707856472457 0.1516556492581395 1.0 1.0 3 Q06787 1 +Dna catabolic process endonucleolytic 0.6913690239972552 1.4315889908131862 0.152261482184778 1.0 1.0 5 O95831 1 +Mitochondrion localization 0.6200214521379098 1.4288142264089514 0.1530576355087203 1.0 1.0 16 Q9BUK6,O75153 2 +Cellular component disassembly involved in execution phase of apoptosis 0.6370402617984422 1.4229109821664836 0.1547619622091613 1.0 1.0 7 Q9UPY3,O95831 2 +Regulation of granulocyte chemotaxis 0.6339583926833803 1.4219428378298595 0.1550428459119031 1.0 1.0 10 Q8NHP6,Q05397,Q07021,Q8NE86 4 +Positive regulation of locomotion 0.4242762921626002 1.420749866067472 0.1553894900566073 1.0 1.0 73 P35241,Q9H6U6,P09601,O60271,Q8NHP6,O95684,Q7Z460,P25054,Q9Y4G8,Q96HY6,Q8WTV0,Q07021,Q9UH99,Q12965,Q13685,Q08722,P61586,Q5JRA6,P31751,O00429,O75116,O95429,Q8NE86,Q9Y263,Q05397 25 +Gene silencing by rna 0.4324237021508854 1.418774950947602 0.1559646377484809 1.0 1.0 40 Q9UIV1,P51114,Q01085,Q9UPY3,Q9BWF3,O75175,Q06787 7 +Peptidyl proline modification 0.5249843028983079 1.416481627900772 0.156634539486516 1.0 1.0 31 P13674,Q96BP3,Q96AY3,Q9Y680,P62942,O15460,Q9BV86,Q32P28,Q9NWM8 9 +Hydrogen peroxide biosynthetic process 0.8002938019373439 1.413569560813075 0.1574883239118503 1.0 1.0 3 P00403 1 +Negative regulation of cellular response to growth factor stimulus 0.6281683366609634 1.4114265841689386 0.1581188689164736 1.0 1.0 12 O14964,Q96TA1,Q05D32,Q9Y2U8,Q8N0X7,P23634 6 +Interleukin 12 production 0.6345652960997042 1.4101972821884945 0.1584814381140786 1.0 1.0 6 P01889,Q08722 2 +Glomerulus development 0.6860835320116598 1.4088913697653678 0.1588672918458002 1.0 1.0 5 P80723 1 +Primary alcohol metabolic process 0.6158314680771231 1.4068024116853723 0.1594859872574434 1.0 1.0 16 Q9BY49,O94788 2 +Regulation of neutrophil migration 0.6324170072031473 1.403811649122849 0.1603749441613913 1.0 1.0 8 Q8NHP6,Q07021,Q8NE86 3 +Vasoconstriction 0.7099074711806579 1.40355488279041 0.1604514381190966 1.0 1.0 4 P20020 1 +Bone mineralization 0.630230838967222 1.397707552593342 0.1622009053358928 1.0 1.0 9 P22413,P20020,P18074 3 +Positive regulation of fibroblast migration 0.6832783524898429 1.3968374853372596 0.1624624470909084 1.0 1.0 5 Q14155,O95429,Q05397 3 +Neuron projection arborization 0.6310834878164474 1.3948685589811984 0.163055479853913 1.0 1.0 7 O14641 1 +Negative regulation of immune response 0.6058074802090753 1.3947429764564918 0.1630933601162207 1.0 1.0 18 P28070,Q9UIV1,Q9Y4E8,P19474,P04439 5 +Regulation of endothelial cell differentiation 0.6309281419546844 1.3932417727532875 0.1635466917312973 1.0 1.0 6 P35611,O14920 2 +Amino acid betaine metabolic process 0.6306084246075544 1.391750759566115 0.1639978855353541 1.0 1.0 6 P49419,P23786 2 +Response to misfolded protein 0.6264201555591296 1.3852652389701767 0.1659713786616916 1.0 1.0 10 P10909,Q9BUN8,P46379,Q9NYU2 4 +Regulation of rig i signaling pathway 0.6282468864155525 1.3839605078301322 0.1663705475408559 1.0 1.0 8 O75179,Q9Y4E8,Q07021 3 +Regulation of dna dependent dna replication initiation 0.6802599450959815 1.383861993825744 0.1664007161571126 1.0 1.0 5 Q96S55,P24941,O60934 3 +Tripartite regional subdivision 0.7045666120377072 1.3814138584173952 0.1671517472205093 1.0 1.0 4 P80723 1 +Blastoderm segmentation 0.7045666120377072 1.3814138584173952 0.1671517472205093 1.0 1.0 4 P80723 1 +Regulation of neuron projection arborization 0.7029260384400706 1.3746105096347092 0.1692522286073918 1.0 1.0 4 O14641 1 +Positive regulation of neuron differentiation 0.6257598258210973 1.3721141187656225 0.1700279148949539 1.0 1.0 8 Q8WUJ1 1 +Positive regulation of smooth muscle cell proliferation 0.6260308454966467 1.3710575156539384 0.1703570272809105 1.0 1.0 7 Q13547,P42224,O95140,P09601 4 +Protein localization to endoplasmic reticulum exit site 0.7017926748886841 1.3699099854203098 0.1707150022729329 1.0 1.0 4 Q5JRA6,O15027 2 +Smad protein signal transduction 0.6238360537164505 1.366918807513385 0.1716507561874087 1.0 1.0 9 P08670,Q9UIQ6,Q01082,P53999,Q96PK6 5 +Neutral lipid biosynthetic process 0.675740047635234 1.3644223965006317 0.1724346630063493 1.0 1.0 5 Q8WTV0,Q8NCC3,Q16822,Q92604 4 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.699589202672185 1.3607701060570934 0.1735863517535629 1.0 1.0 4 Q96TA1 1 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.699589202672185 1.3607701060570934 0.1735863517535629 1.0 1.0 4 Q96TA1 1 +Cellular response to hydrogen peroxide 0.6033407112590069 1.3600170596962016 0.1738245254230854 1.0 1.0 17 Q99720,O95831 2 +Rna interference 0.6231402249362357 1.359631016133262 0.1739467179836902 1.0 1.0 8 Q9UPY3 1 +Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.7854471268276211 1.356177135975648 0.175042814897214 1.0 1.0 3 Q99729,A2RRP1 2 +Regulation of vasoconstriction 0.7854350725347655 1.356130525624693 0.1750576419689467 1.0 1.0 3 P20020 1 +Dna methylation involved in gamete generation 0.785268135156515 1.3554850275096644 0.1752630757170949 1.0 1.0 3 Q8N2A8 1 +Glomerular epithelial cell differentiation 0.6962360705146659 1.3468588421170409 0.1780256992920788 1.0 1.0 4 P80723 1 +Glomerular epithelium development 0.6962360705146659 1.3468588421170409 0.1780256992920788 1.0 1.0 4 P80723 1 +Peptidyl asparagine modification 0.6204400614292177 1.346758583957066 0.1780579974517366 1.0 1.0 8 Q8TCJ2,Q9NYU2 2 +Protein localization to golgi apparatus 0.6181922624763232 1.34517575240029 0.1785684846547812 1.0 1.0 10 Q8TD16,O14976 2 +Cilium or flagellum dependent cell motility 0.6934828506469315 1.3354344210668667 0.1817342053232802 1.0 1.0 4 Q9GZT3 1 +Sperm motility 0.6934828506469315 1.3354344210668667 0.1817342053232802 1.0 1.0 4 Q9GZT3 1 +Regulation of mrna processing 0.4210140681361198 1.3327761383092438 0.1826052785469096 1.0 1.0 77 Q12872,Q9Y5S9,P52756,Q09161,Q96E39,P31483,Q13242,P61978,Q13573,P98175,Q08170,P51114,P62995,P84103,Q15637,O00267,P19338,Q6PJT7,Q06787,Q16629,P38159,Q07021,O75150,Q5VTR2,Q9Y2W1,P98179,P21127,P51116,Q8N684,Q96PU8,Q13247,Q9BWF3,Q14011,P22626 34 +Regulation of alternative mrna splicing via spliceosome 0.5570920920808748 1.3290255852906585 0.1838395289789285 1.0 1.0 25 P51116,P38159,Q9Y5S9,P98175,P51114,P52756,P62995,Q9Y2W1,Q13247,P31483,Q9BWF3,Q06787 12 +Cellular response to estrogen stimulus 0.6913266372940755 1.3264862165370832 0.1846786977075343 1.0 1.0 4 Q8IZL8,Q9H6U6 2 +Regulation of camp dependent protein kinase activity 0.6662021578083304 1.3233694977267765 0.1857125302635514 1.0 1.0 5 Q9Y4G8,P23634,P10644 3 +Cardiolipin metabolic process 0.6141003335943742 1.314656712263455 0.1886253009149925 1.0 1.0 6 Q6UWP7 1 +Response to insulin 0.3912866430564802 1.3144627572297791 0.1886905232092799 1.0 1.0 57 Q16836,Q08170,Q9BZF1,P25054,Q9UQB8,Q9H1E3,Q13243,Q15043,P61026,Q12965,O60763,P62993,P31751,P42224,P22413,P20020,Q8WWQ0,P43490,Q6ZWJ1,Q9HCD5 20 +Negative regulation of immune effector process 0.613619437936533 1.3124862268590158 0.1893561302006603 1.0 1.0 7 P01889,Q08722,P04439 3 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.5014072814350043 1.3122493742373131 0.1894360075340619 1.0 1.0 32 Q07021,P01889,Q9NUQ9,O60934,Q9UQ84,P10909,P04439,O15400 8 +Fc gamma receptor signaling pathway 0.6877935040063337 1.3118223220547989 0.1895800914432381 1.0 1.0 4 Q05397 1 +Negative regulation of cell junction assembly 0.6124789790034408 1.308777681129098 0.1906096692777084 1.0 1.0 8 O14920 1 +Mismatch repair 0.6088741109010644 1.3064864950187467 0.1913871686823571 1.0 1.0 11 Q9UQ84 1 +Negative regulation of release of cytochrome c from mitochondria 0.6122991326276805 1.306249841971898 0.191467608144976 1.0 1.0 7 P10909 1 +Response to interleukin 1 0.5997260484566728 1.3056732185308342 0.1916637092437274 1.0 1.0 15 Q08722,P38159,O14920,P78318 4 +Collagen biosynthetic process 0.6855136174193996 1.3023591875852103 0.1927936272799586 1.0 1.0 4 Q92791 1 +Regulation of kidney development 0.7714770456853269 1.3021576676106887 0.1928624930086679 1.0 1.0 3 P80723 1 +Metanephric mesenchyme development 0.7714770456853269 1.3021576676106887 0.1928624930086679 1.0 1.0 3 P80723 1 +Kidney mesenchyme development 0.7714770456853269 1.3021576676106887 0.1928624930086679 1.0 1.0 3 P80723 1 +Positive regulation of rna splicing 0.5645635991553091 1.3013345530613654 0.1931439648959827 1.0 1.0 23 P38159,P19338,Q8WVV9,O75312,P62995,Q09161,Q9Y2W1,Q96E39,P98179,Q96QD8,Q14011,Q13243 12 +Regulation of muscle organ development 0.6102816626334822 1.2982882870746344 0.1941882897710163 1.0 1.0 8 O94966,Q96TA1 2 +Regulation of glucose import 0.6083161319025123 1.296993752127546 0.1946333365431898 1.0 1.0 10 O75298,Q9BZF1,P31751 3 +Amino acid betaine transport 0.9925220938137314 1.292393868170491 0.1962207791357528 1.0 1.0 2 O43772 1 +Regulation of inclusion body assembly 0.6092059861659356 1.2916360960695903 0.1964831974863625 1.0 1.0 7 P10909 1 +Vitamin a metabolic process 0.9901427600271916 1.2838253305290643 0.1992030784207688 1.0 1.0 2 O94788 1 +Protein n linked glycosylation 0.5923790836947691 1.283307722574765 0.1993842881800391 1.0 1.0 16 Q8TCJ2,Q96AA3,Q9HC07,Q13724 4 +Isoprenoid metabolic process 0.5610840325227682 1.28080564000527 0.2002619425325038 1.0 1.0 23 P48449,Q9BY49,O94788 3 +Modulation by host of viral genome replication 0.6057265588478361 1.2751922446670878 0.2022412056183737 1.0 1.0 7 Q06787,Q9H1E3 2 +Peptide catabolic process 0.6030818165339638 1.2714372077092146 0.2035731528346434 1.0 1.0 10 P55786 1 +Sequestering of triglyceride 0.6779707289774315 1.2710498241975277 0.2037109239606866 1.0 1.0 4 P22413,Q9BZF1 2 +Rna stabilization 0.5338505258083804 1.267163123014613 0.2050969687058708 1.0 1.0 27 P98175,Q9Y2W1,Q92804,Q9H074,P35637,P11940,Q14011,Q08J23,P49137,P67809 10 +Triglyceride biosynthetic process 0.6755102040816532 1.260837127008666 0.2073675343422234 1.0 1.0 4 Q8WTV0,Q16822,Q92604 3 +Er associated misfolded protein catabolic process 0.6024690889939714 1.2597933120660714 0.2077439330379005 1.0 1.0 7 Q9BUN8,Q9NYU2,P46379 3 +Glucose import 0.597412199172346 1.257830434532535 0.2084530864490745 1.0 1.0 12 O75298,Q9BZF1,P31751 3 +Positive regulation of neurotransmitter transport 0.6509016672337457 1.25745589201202 0.2085886012442208 1.0 1.0 5 P05556,Q96EV8,P20337,Q15042 4 +Cristae formation 0.5996169072953873 1.2545143686491376 0.2096551064387486 1.0 1.0 10 Q96E52,Q16891,Q9NVH1,Q6UXV4 4 +Neural retina development 0.6007034155931631 1.2519767788223866 0.2105783255428051 1.0 1.0 6 P20020,P54802 2 +Positive regulation of mitochondrial fission 0.6493848628397456 1.2509198033872466 0.2109637379723494 1.0 1.0 5 O00429,Q8NE86 2 +Positive regulation of insulin secretion 0.6001351744874973 1.2498255460575962 0.2113632819884059 1.0 1.0 8 O00330 1 +Reverse cholesterol transport 0.9792658055744392 1.2447043611435609 0.2132404423014282 1.0 1.0 2 P10909 1 +Regulation of phospholipid catabolic process 0.9792658055744384 1.244704361143557 0.2132404423014295 1.0 1.0 2 O75874 1 +Cellular response to peptide hormone stimulus 0.3857325909142302 1.2427252760913368 0.2139690863823706 1.0 1.0 58 P46821,Q92572,P16435,Q9BZF1,P25054,Q9UQB8,Q9H1E3,Q13243,Q15043,P61026,Q12965,O60343,O60763,O15294,P62993,P31751,P42224,P22413,P20020,Q8WWQ0,P43490,Q6ZWJ1,Q9HCD5,P41240,O75116,Q05397 26 +Positive regulation of receptor mediated endocytosis 0.5940485418701207 1.241003230504446 0.2146045554786138 1.0 1.0 12 Q9UL25,Q06787,P10909,P61978 4 +Positive regulation of neurotransmitter secretion 0.755247363567983 1.2394325065822358 0.2151853693874632 1.0 1.0 3 Q15042 1 +Glutamate secretion neurotransmission 0.754845290717453 1.2378795079910017 0.2157607416617668 1.0 1.0 3 Q96EV8,Q15042 2 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.590902034079764 1.2347498039763116 0.2169236340442228 1.0 1.0 13 O43657,Q9Y4E8,Q07021,O75179 4 +Positive regulation of dna dependent dna replication 0.6452064793612 1.2329146447739605 0.2176076110208811 1.0 1.0 5 P24941,O95785 2 +Response to food 0.5962090225415562 1.2309359559199111 0.2183468183745316 1.0 1.0 6 P80303,Q9UMX5 2 +Calcium ion export 0.6446779479807369 1.2306371919004302 0.2184585885639698 1.0 1.0 5 P20020 1 +Negative regulation of phosphatase activity 0.5954723222012966 1.2300459798628092 0.218679887220587 1.0 1.0 9 P62942,O14920,O95429,O75116 4 +Regulation of mrna polyadenylation 0.5917314906231307 1.2294106138884684 0.2189178927685864 1.0 1.0 12 O75150,Q5VTR2,Q09161,O00267,Q6PJT7 5 +Lipid droplet organization 0.5957593580937204 1.228916373937096 0.2191031616783481 1.0 1.0 8 Q14534,Q9Y679,Q9NP72,Q15042,Q8N0X7 5 +Carbohydrate transport 0.5709168081172886 1.22660369602872 0.2199715793682306 1.0 1.0 19 P22413,O75298,Q9BZF1,Q96AA3,P31751 5 +Regulation of mrna export from nucleus 0.6670049778025342 1.2255427941682169 0.2203707765588753 1.0 1.0 4 Q08J23 1 +Deadenylation dependent decapping of nuclear transcribed mrna 0.7506101140573793 1.221525118913495 0.2218872609429552 1.0 1.0 3 Q9UIV1 1 +Regulation of presynaptic cytosolic calcium ion concentration 0.7502547761158269 1.2201533069265826 0.2224067637724136 1.0 1.0 3 P20020 1 +Regulation of leukocyte chemotaxis 0.583066452922664 1.219021924880206 0.2228358710325042 1.0 1.0 15 Q8NHP6,Q05397,Q07021,Q8NE86 4 +Mrna 5 splice site recognition 0.7496996901601716 1.218010465822896 0.223219995635699 1.0 1.0 3 Q07955 1 +Regulation of protein folding 0.6649659863945605 1.2170842279752712 0.2235721708959686 1.0 1.0 4 Q9H2J4,Q9UL15,P08621 3 +Regulation of synaptic vesicle recycling 0.5930810264549244 1.216290203879319 0.2238743919079904 1.0 1.0 6 P0DP25,Q9Y263,Q00535,Q13464 4 +Positive regulation of interleukin 2 production 0.5923421390691038 1.212830506420283 0.2251946293514635 1.0 1.0 6 Q01082,Q92990 2 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.6638296421015782 1.2123708044052512 0.2253704715445981 1.0 1.0 4 O00330 1 +Defense response to gram positive bacterium 0.663605442176866 1.2114409032289215 0.2257264709581323 1.0 1.0 4 Q96JM3,Q96EE3,P04439 3 +Regulation of cell aging 0.591441963536042 1.210575635275425 0.2260580868608359 1.0 1.0 9 P67809 1 +Antigen processing and presentation of peptide antigen via mhc class i 0.5859237006065355 1.2095257943809894 0.2264609074219494 1.0 1.0 13 P01889,O14920,Q9NZ08,P04439 4 +Regulation of centriole replication 0.6629251700680129 1.208619490903413 0.2268090647778615 1.0 1.0 4 P06748,O75351,Q96PK6 3 +Regulation of mononuclear cell migration 0.5809534826627545 1.208027946214902 0.227036513037274 1.0 1.0 15 Q8NHP6,Q08722,Q5JRA6,Q05397 4 +Regulation of glucose transmembrane transport 0.5858956822623647 1.2002113530867962 0.2300572672080596 1.0 1.0 12 P22413,Q9BZF1,P31751,O75298 4 +Secretory granule organization 0.6373070964710456 1.1988797996032297 0.2305746874840781 1.0 1.0 5 P16220,Q96EV8 2 +Establishment of planar polarity of embryonic epithelium 0.6602627796524289 1.197579043215967 0.231080938697608 1.0 1.0 4 Q13308 1 +Camera type eye development 0.5086810058503936 1.196095019938936 0.231659480819298 1.0 1.0 29 Q13547,Q96EV8,P20020,P08670,O94788,Q15042,Q15293,P54802 8 +Striated muscle adaptation 0.6595266730023456 1.194527072936321 0.2322718570461535 1.0 1.0 4 Q13555,P23634 2 +Myelin maintenance 0.6360351456596304 1.193400670907895 0.2327124923651675 1.0 1.0 5 P10909 1 +Regulation of exosomal secretion 0.5875186684831566 1.1916223996890496 0.2334093378973052 1.0 1.0 9 O14964,Q92783,Q9Y3E7,Q9UN37,O75351 5 +Mitochondrial transmembrane transport 0.3719569859442246 1.1895923316724923 0.2342066612801505 1.0 1.0 52 Q9H2D1,P00846,O43772,Q16762,O95831,P23786,Q9Y619,Q96AQ8,Q8NE86,Q9BQT8 10 +Antigen processing and presentation of peptide antigen 0.5795952231198078 1.1881901363772829 0.2347585088428072 1.0 1.0 14 P01889,O14920,Q9NZ08,P04439 4 +Negative regulation of defense response 0.5207272148122581 1.1834750096747193 0.2366209449502723 1.0 1.0 27 P28070,Q9UIV1,P01889,O43657,Q9Y4E8,P19474,P04439 7 +Establishment of endothelial barrier 0.5761910274701959 1.1832495312185145 0.2367102680502801 1.0 1.0 15 P35241,Q9UDY2,O14920,Q9Y4G8,O75116,P35611 6 +Positive regulation of mrna splicing via spliceosome 0.5725178711622526 1.1785280586244369 0.2385861531139492 1.0 1.0 16 P38159,P62995,Q09161,Q9Y2W1,Q96E39,P98179,P19338,Q14011 8 +Adrenergic receptor signaling pathway 0.7389906097229895 1.1767009319830026 0.2393148957421667 1.0 1.0 3 Q9Y4G8 1 +Adenylate cyclase activating g protein coupled receptor signaling pathway 0.7389906097229892 1.1767009319830026 0.2393148957421667 1.0 1.0 3 Q9Y4G8 1 +Biomineralization 0.5811773634743778 1.1766049808405827 0.2393532088349683 1.0 1.0 12 P22413,P20020,Q9UNW1,Q6P4Q7,P18074 5 +Protein k63 linked ubiquitination 0.5810799973018753 1.176117886661496 0.2395477712536686 1.0 1.0 12 P19474 1 +Cilium movement 0.6313834410536093 1.173366845579497 0.2406487266766017 1.0 1.0 5 Q9GZT3,P23634 2 +Positive regulation of cellular response to insulin stimulus 0.5836463193976755 1.1721153566274083 0.241150745245998 1.0 1.0 6 Q9H1E3,Q12965 2 +Negative regulation of dephosphorylation 0.5777520739484903 1.168125091682651 0.2427563104613443 1.0 1.0 13 O75116,O14920,P62942,O95429,O43768 5 +Positive regulation of intracellular protein transport 0.3668517597616651 1.1667476231302305 0.2433123044948328 1.0 1.0 50 P27105,Q9H6U6,O75312,P55786,Q9H270,Q05D32,Q9C0E2,Q12965,Q9Y282,P12270,P50402,P31751 12 +Regulation of actin cytoskeleton reorganization 0.5818458365881098 1.1642207089589969 0.2443345799030956 1.0 1.0 9 Q9Y5K6,Q9UQB8,P52565,Q9H6U6 4 +Positive regulation of peptide secretion 0.5806127081722142 1.1616737370711616 0.2453680175635255 1.0 1.0 10 O00330 1 +Regulation of transcription involved in g1 s transition of mitotic cell cycle 0.734936065284179 1.1610792567966024 0.2456096695223681 1.0 1.0 3 O75312 1 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.5804801256931051 1.155904566634932 0.2477201945388425 1.0 1.0 8 O00330,Q86TM6,O95881,Q9Y4L1 4 +Protein localization to nuclear envelope 0.5777482457100189 1.1445073273807933 0.2524133008537945 1.0 1.0 6 Q8NFQ8 1 +Wound healing 0.3730998282060977 1.1421795368704792 0.2533793999689719 1.0 1.0 56 Q13308,P42785,Q96AY3,Q03001,Q5JRA6,Q8WTV0,Q05397 7 +Immune response regulating signaling pathway 0.3713645152350807 1.1389963453626155 0.2547046785153548 1.0 1.0 55 Q9UJZ1,O95999,Q07021,O14920,Q9NUD5,O43657,Q08722,Q9Y4E8,Q96IZ0,Q96RT1,O75179,P04439,Q05397,P46379 14 +Gastrulation with mouth forming second 0.729013144660106 1.13828104251749 0.2550031473821774 1.0 1.0 3 Q4VCS5 1 +Collateral sprouting 0.7285120263616298 1.136353477555534 0.2558086578720759 1.0 1.0 3 Q8N0X7 1 +Regulation of collateral sprouting 0.7285120263616298 1.136353477555534 0.2558086578720759 1.0 1.0 3 Q8N0X7 1 +Protein geranylgeranylation 0.72696361781707 1.130398864442978 0.2583081924043042 1.0 1.0 3 Q92696,P24386 2 +Memory 0.5731579947391803 1.125274468942803 0.2604727451118023 1.0 1.0 10 Q96KQ7,Q96EV8,P78559,O00264 4 +Interleukin 2 production 0.5737404102480141 1.123955795233082 0.2610317794023751 1.0 1.0 7 Q01082,Q92990 2 +Collagen metabolic process 0.5736160178135237 1.123123063271121 0.2613852322348662 1.0 1.0 8 Q92791,Q32P28 2 +Intracellular lipid transport 0.5710853487618024 1.115159302484959 0.2647821625311954 1.0 1.0 10 O43772 1 +Tricarboxylic acid metabolic process 0.5715404287403222 1.1144698077864634 0.2650776900368592 1.0 1.0 9 O75874,P48735 2 +Abscission 0.7211832709962718 1.1081893625047912 0.2677800438961326 1.0 1.0 3 P53990,Q8N0X7 2 +Vascular associated smooth muscle contraction 0.7207073472862389 1.10636220709409 0.2685697765403083 1.0 1.0 3 P20020 1 +Carbohydrate transmembrane transport 0.5601933047770673 1.1000730853972436 0.271300279546979 1.0 1.0 15 P22413,Q9BZF1,P31751,O75298 4 +Regulation of establishment or maintenance of cell polarity 0.5686109396052619 1.0997276056581458 0.2714508230746197 1.0 1.0 7 Q9NUQ9,Q9H6U6 2 +Planar cell polarity pathway involved in neural tube closure 0.9381373215499664 1.097789515326787 0.2722964107797558 1.0 1.0 2 Q13308 1 +Cochlea morphogenesis 0.9381373215499664 1.097789515326787 0.2722964107797558 1.0 1.0 2 Q13308 1 +Prenylation 0.6358301882736361 1.0964623315608286 0.2728764991899899 1.0 1.0 4 Q92696,P24386 2 +Transcytosis 0.5673167393848664 1.0957156401320531 0.2732032360504122 1.0 1.0 6 P55899 1 +Regulation of appetite 0.937457511896662 1.0953785055440357 0.2733508468644761 1.0 1.0 2 Q9UMX5 1 +Regulation of response to food 0.937457511896662 1.0953785055440357 0.2733508468644761 1.0 1.0 2 Q9UMX5 1 +Negative regulation of response to food 0.937457511896662 1.0953785055440357 0.2733508468644761 1.0 1.0 2 Q9UMX5 1 +Cellular response to lipoprotein particle stimulus 0.7177830669840329 1.095140580007273 0.2734550528602599 1.0 1.0 3 Q5JRA6,O15118 2 +Positive regulation of exosomal secretion 0.5672719079705827 1.0928480217224883 0.2744605330963523 1.0 1.0 8 O14964,O75351,Q9UN37,Q92783 4 +Immune effector process 0.3806639223190339 1.090371658084634 0.2755494612684577 1.0 1.0 65 O95999,Q07021,P01889,Q9NUQ9,O60934,Q9UQ84,Q08722,O75179,P04439,P10909,O15400,Q05397 12 +Phosphatidylglycerol metabolic process 0.5659538641975543 1.0875255136780018 0.2768046292799366 1.0 1.0 9 Q8NCC3,Q9UJZ1,Q6UWP7 3 +Glycoprotein metabolic process 0.3660379664661822 1.0841637872669032 0.2782921846540456 1.0 1.0 55 Q86TM6,Q8TCJ2,Q13724,Q96IZ0,Q9HC07,P33908,Q08379,Q9NQX7,O60701,Q96AA3,P35610,Q9NYU2 12 +Positive regulation of rig i signaling pathway 0.6101749780956004 1.0821709652569358 0.2791765673670008 1.0 1.0 5 O75179,Q9Y4E8 2 +Regulation of natural killer cell mediated immunity 0.6322391242600043 1.081643545022881 0.2794109475788788 1.0 1.0 4 P04439 1 +Gdp metabolic process 0.631180591865032 1.077278174935698 0.281356009621905 1.0 1.0 4 Q00013 1 +Fat soluble vitamin metabolic process 0.6086192759431537 1.075495111685489 0.2821531195978772 1.0 1.0 5 O94788 1 +Regulation of smad protein signal transduction 0.710256223871238 1.0663014471402392 0.2862873955565266 1.0 1.0 3 Q01082 1 +Acetyl coa biosynthetic process from pyruvate 0.5607086352540686 1.0648457083197924 0.2869457569202982 1.0 1.0 6 O00330 1 +Organic acid transmembrane transport 0.4956873254201603 1.0648197910220036 0.2869574873332763 1.0 1.0 28 O60831,O43772,P23786,Q96QD8,Q9BQT8,P31751 6 +Cellular response to reactive oxygen species 0.5009298834890789 1.0573548830692598 0.2903496540668788 1.0 1.0 27 Q99720,O95831 2 +Mrna modification 0.5589506257766663 1.053786244489788 0.2919807926254671 1.0 1.0 9 Q96FX7,Q08J23 2 +Protein complex oligomerization 0.3671401615599322 1.0519284769443982 0.2928323655623512 1.0 1.0 58 Q99720,P38159,Q9UJZ1,O95999,Q9UN86,O94788,Q8NE86,Q08379,P35637,Q8NHH9,O60701,Q96CX2 12 +Amyloid precursor protein catabolic process 0.5392024360015255 1.0517603077713351 0.2929095340196919 1.0 1.0 19 Q15392,Q13526,O75298,P62942,P10909 5 +Metal ion export 0.5571899659463997 1.051224978678441 0.2931552734981062 1.0 1.0 11 P20020,P05026 2 +Cellular response to peptide 0.3781652977525214 1.0509519358513668 0.293280665373151 1.0 1.0 66 P46821,Q92572,P16435,Q9BZF1,P25054,Q9UQB8,Q9H1E3,Q13243,Q15043,P61026,Q9NZZ3,Q12965,O60343,O60763,Q9UNS1,O15294,P62993,P31751,P42224,P22413,P20020,Q8WWQ0,P43490,P08670,Q6ZWJ1,Q9HCD5,P41240,O75116,Q05397 29 +Positive regulation of small gtpase mediated signal transduction 0.6246732100189725 1.050471856015067 0.2935012239512509 1.0 1.0 4 Q9UQ13 1 +Positive regulation of rna binding 0.6025291613421859 1.0493854913367715 0.2940007330362681 1.0 1.0 5 Q06787 1 +Regulation of lipoprotein particle clearance 0.6024543421639276 1.0490649852702332 0.2941482101572821 1.0 1.0 5 Q92945,P41240,P61978 3 +Regulation of low density lipoprotein particle clearance 0.6024543421639276 1.0490649852702332 0.2941482101572821 1.0 1.0 5 Q92945,P41240,P61978 3 +Muscle cell differentiation 0.3682363408824292 1.048776750984158 0.2942808801512753 1.0 1.0 59 Q13547,O60271,Q9H7B4,Q92990,P09493,Q96TA1,P11310,Q9BWF3,O75179,Q9P2K5,P67809 11 +2 oxoglutarate metabolic process 0.5575963529302883 1.0472676666408869 0.2949761442227103 1.0 1.0 9 O75874,P48735 2 +Establishment of planar polarity involved in neural tube closure 0.7051032971904845 1.0465987390180724 0.2952846837463623 1.0 1.0 3 Q13308 1 +Mitochondrial fusion 0.5492606148220794 1.043345086468692 0.2967884965698879 1.0 1.0 15 Q8N2A8,Q8NAN2,Q9UJZ1,Q8TB36,Q9H300,Q96E52,Q9NX63,Q9Y6C9,O60313 9 +Apical protein localization 0.621340224038022 1.036763790108352 0.2998459547745264 1.0 1.0 4 Q9HD26 1 +Positive regulation of protein modification by small protein conjugation or removal 0.3790610400833293 1.0343437795516015 0.3009754770144921 1.0 1.0 41 Q13526,O95999,O75150,Q9BUN8,Q5VTR2,P62942,Q92564,Q96JB5 8 +Lipid localization 0.3805961873539516 1.0340126013273363 0.3011302722303304 1.0 1.0 69 Q99720,O43772,Q9UID3,Q14534,P23786,P07602,O15260,P10909,Q8WTV0,Q96AA3,P35610,P31751,P09455 13 +Regulation of insulin receptor signaling pathway 0.5536734576812405 1.0339129460453165 0.3011768622426229 1.0 1.0 11 Q9HCD5,Q9BZF1,Q9H1E3 3 +Netrin activated signaling pathway 0.9197824609109396 1.0329461157453388 0.3016291159587241 1.0 1.0 2 Q05397 1 +Regulation of long term synaptic potentiation 0.5982453755599199 1.031045994110543 0.302519251647017 1.0 1.0 5 Q9BPZ3,P21359,Q92542 3 +Negative regulation of nf kappab transcription factor activity 0.5480608511950371 1.0266067462333726 0.3046056760949849 1.0 1.0 14 Q96JB5,P09525,P19474,Q96RT1 4 +Regulation of glycoprotein metabolic process 0.5528712451286398 1.026425228742357 0.3046911912087444 1.0 1.0 10 Q9NQX7,Q96IZ0,Q08379 3 +Regulation of mitotic recombination 0.6994219653179317 1.024918524577818 0.3054016330760718 1.0 1.0 3 Q92878,P18074 2 +Polarized epithelial cell differentiation 0.551971303864558 1.0212872952312335 0.307118343893936 1.0 1.0 7 Q13308 1 +Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.5959031754649659 1.021028837750546 0.3072407761597273 1.0 1.0 5 Q99729,Q9Y5S9,A2RRP1 3 +Kidney morphogenesis 0.5512412659476172 1.0206945678228443 0.3073991689833277 1.0 1.0 6 P80723 1 +Negative regulation of tor signaling 0.6170068027210829 1.0189654768510863 0.3082193565997961 1.0 1.0 4 O75340,Q96B36,P49840 3 +Tetrapyrrole catabolic process 0.6158758310980644 1.0143251479230897 0.3104276281051845 1.0 1.0 4 P30519 1 +Negative regulation of small gtpase mediated signal transduction 0.5496590926189246 1.014170116549703 0.3105015853403525 1.0 1.0 11 P05556,P37198,Q9NUQ9,Q9Y5K6,P16949,P21359,O95140,O95630 8 +Mirna metabolic process 0.5504510504169724 1.0141365253355337 0.3105176114575756 1.0 1.0 7 Q8TCS8,Q9UPY3,Q92945,Q92841,O95453 5 +Cytoplasmic pattern recognition receptor signaling pathway 0.5411948435963434 1.0136139148147771 0.3107670153527193 1.0 1.0 16 Q07021,O43657,Q9Y4E8,Q96RT1,O75179 5 +Regulation of blood pressure 0.5385174247534654 1.013475008106012 0.3108333276266712 1.0 1.0 17 Q9NZ08,P09493,P42785,P20020 4 +Chemokine production 0.549415481054111 1.012192650397035 0.3114459496161053 1.0 1.0 6 P14174,P19525,P09601,Q96RT1 4 +Activation of innate immune response 0.5372747524123289 1.006860855730327 0.3140016451964751 1.0 1.0 17 P23246,Q15233,O14920,Q9NUD5,Q13177,P12956,Q96PK6,P43243,Q8WXF1 9 +Fc receptor mediated stimulatory signaling pathway 0.592163889301927 1.0050527601477026 0.3148714453749148 1.0 1.0 5 Q05397 1 +Post translational protein modification 0.5476301533811229 1.004200769998287 0.3152818510591062 1.0 1.0 11 O60725,Q32P28,Q9HA64 3 +Crd mediated mrna stabilization 0.5482604736141632 1.0023945957424842 0.3161530512097241 1.0 1.0 9 P11940,Q9H074,P67809 3 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5482604736141632 1.0023945957424842 0.3161530512097241 1.0 1.0 9 P11940,Q9H074,P67809 3 +Negative regulation of natural killer cell mediated immunity 0.9106050305914344 1.0007439457856429 0.3169506155813795 1.0 1.0 2 P04439 1 +Detection of other organism 0.9106050305914344 1.0007439457856429 0.3169506155813795 1.0 1.0 2 P04439 1 +Protection from natural killer cell mediated cytotoxicity 0.9106050305914344 1.0007439457856429 0.3169506155813795 1.0 1.0 2 P04439 1 +Positive regulation of embryonic development 0.5475522551436678 0.9989870776576252 0.3178009512337914 1.0 1.0 8 Q68CQ4,Q4VCS5,Q96TA1 3 +Meiotic spindle assembly 0.9099252209381288 0.998365054500152 0.3181023725559888 1.0 1.0 2 Q08379 1 +3 utr mediated mrna destabilization 0.54627951922878 0.9976008364766198 0.3184729553135705 1.0 1.0 6 Q92945,Q14103,Q9HCE1 3 +Negative regulation of protein targeting to mitochondrion 0.692047507103867 0.9968517041073032 0.3188364970927115 1.0 1.0 3 O95429 1 +Negative regulation of cytoskeleton organization 0.374980079078326 0.9964685619912452 0.3190225347138542 1.0 1.0 41 P35241,Q9NUQ9,P04350,Q01082,Q13177,Q7Z460,P16949,Q13813,O15344,O15020,P25054,P35611,Q96PK6,P52907,Q14155 15 +Response to hydrogen peroxide 0.5077032368404732 0.994931023375392 0.3197698130517095 1.0 1.0 24 Q99720,O95831 2 +Nitric oxide mediated signal transduction 0.6890633197558794 0.9855200915310072 0.324368667428581 1.0 1.0 3 O00330 1 +Synaptonemal complex organization 0.5436565912796619 0.9822195387960924 0.3259917037640272 1.0 1.0 7 Q92791,Q96KQ7,O60216,P54652,P46379 5 +Positive regulation of vascular permeability 0.6879198250708557 0.9811822138145024 0.3265028935313512 1.0 1.0 3 Q9UDY2 1 +Positive regulation of blood brain barrier permeability 0.6879198250708557 0.9811822138145024 0.3265028935313512 1.0 1.0 3 Q9UDY2 1 +Regulation of blood brain barrier permeability 0.6879198250708557 0.9811822138145024 0.3265028935313512 1.0 1.0 3 Q9UDY2 1 +Positive regulation of mitotic nuclear division 0.5404896283112008 0.973667837008086 0.3302214918280572 1.0 1.0 12 Q15398,P37198,Q8WWQ0,Q96MF7,Q13042,Q9UJX3,Q9UJX5 7 +Transcription coupled nucleotide excision repair 0.6857776569804787 0.97306234024508 0.3305223196453999 1.0 1.0 3 P18074 1 +Negative regulation of notch signaling pathway 0.9024473147518628 0.9722597339890942 0.3309213502638026 1.0 1.0 2 Q96TA1 1 +Negative regulation of smooth muscle cell proliferation 0.5412377032093079 0.9708750725310212 0.3316104927061676 1.0 1.0 7 P09601,P61586,Q15637,P09493 4 +Protein localization to microtubule organizing center 0.5415956835382036 0.970441665678938 0.3318263886847803 1.0 1.0 9 P25054,Q14789 2 +Establishment of lymphocyte polarity 0.6047619047618953 0.9688435280801608 0.33262326500703 1.0 1.0 4 Q14160,P35579,Q96L92 3 +Fat cell differentiation 0.4926679868362835 0.9682898827825782 0.3328996161017856 1.0 1.0 26 Q8N4Q0,Q9NZ08 2 +Negative regulation of striated muscle cell differentiation 0.583177698783244 0.9667505186829995 0.3336687658328994 1.0 1.0 5 P67809 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5384333335400943 0.963470615152946 0.3353114037305911 1.0 1.0 12 P11940,Q9H074,Q9UIV1,P67809 4 +Amyloid beta clearance 0.5400886720971538 0.9632276686551252 0.3354332827743218 1.0 1.0 9 Q16850,P10909 2 +Positive regulation of mitochondrial membrane potential 0.6828611264544826 0.962021300399163 0.3360389043798246 1.0 1.0 3 P31751 1 +Actin crosslink formation 0.6029318863325035 0.961377000926128 0.3363626440339455 1.0 1.0 4 Q9UQB8 1 +Negative regulation of lipid localization 0.6826841028531494 0.9613516814065376 0.3363753703702712 1.0 1.0 3 P31751 1 +Purine ribonucleoside salvage 0.5818041439193811 0.9609085042702776 0.3365981744157409 1.0 1.0 5 P55263 1 +Nucleoside salvage 0.5818041439193811 0.9609085042702776 0.3365981744157409 1.0 1.0 5 P55263 1 +Non canonical wnt signaling pathway 0.538184920544269 0.9600091821339044 0.337050593689971 1.0 1.0 6 Q13308 1 +Cellular response to retinoic acid 0.5380335589780846 0.9571434443156956 0.3384948581830329 1.0 1.0 11 Q13308,P16220,Q9P0J0,O94788 4 +Nuclear transcribed mrna poly a tail shortening 0.5373133589452059 0.9559685822392744 0.3390881076383119 1.0 1.0 6 Q9UIV1 1 +Methylguanosine cap decapping 0.5365543585572639 0.9524510160672462 0.3408682970200574 1.0 1.0 6 Q9UIV1 1 +Rna decapping 0.5365543585572639 0.9524510160672462 0.3408682970200574 1.0 1.0 6 Q9UIV1 1 +Regulation of cell morphogenesis 0.3642942227543515 0.9520199590324712 0.3410868597020213 1.0 1.0 63 Q8WWQ0,O60271,P09493,P35241,Q07021,Q9UEE9,Q9UL25,O14641,Q71RC2,Q7Z406,Q9UQB8,Q05397,Q9Y263,Q15334 14 +Nephron epithelium development 0.5367751669132224 0.9483825308120084 0.3429347494106978 1.0 1.0 10 P35610,P80723 2 +Response to corticosteroid 0.4832007284995639 0.944934618527237 0.3446922563277859 1.0 1.0 27 O00330,Q9H7B4 2 +Regulation of cell cell adhesion 0.358634740287744 0.9428075145692448 0.3457793673530536 1.0 1.0 42 O95999,Q92990,P35241,Q9NUQ9,Q5JRA6,Q08722,P61586,Q96IZ0,O43290,P10644,P41240,P04439,Q13951,P30825,Q05397 15 +Regulation of vasculogenesis 0.8936097892590074 0.9415646338879136 0.3464155835483593 1.0 1.0 2 Q9NWT6 1 +Positive regulation of vasculogenesis 0.8936097892590074 0.9415646338879136 0.3464155835483593 1.0 1.0 2 Q9NWT6 1 +Regulation of cell shape 0.4825351309220689 0.940730143467445 0.3468431675243288 1.0 1.0 27 Q8WWQ0,P09493,P35241,Q9UEE9,Q7Z406,Q9UQB8,Q05397 7 +Regulation of gtpase activity 0.3489648492200297 0.937904594027568 0.3482934420785848 1.0 1.0 53 Q9UJF2,Q13526,Q9H6U6,Q9H2M9,Q4VCS5,Q15042,P31751,Q15404,O14641,Q8WU90,Q9Y4G8,Q66K14,Q05397 13 +Ncrna export from nucleus 0.5333144564932586 0.937448780116435 0.3485277589845628 1.0 1.0 6 P06748,Q09161,Q9H814 3 +Embryonic body morphogenesis 0.6761166893365511 0.9365547665378116 0.3489876288026894 1.0 1.0 3 Q7Z460 1 +Striated muscle cell differentiation 0.3684556600829105 0.9360660646131136 0.3492391740269838 1.0 1.0 41 O60271,Q9H7B4,P09493,Q96TA1,P11310,Q9P2K5,P67809 7 +Negative regulation of biomineralization 0.6759830188407268 0.9360510071430508 0.3492469262533395 1.0 1.0 3 P22413 1 +Hair follicle maturation 0.5328580631234116 0.9353372211045342 0.349614539034321 1.0 1.0 6 P21359,Q08J23,P18074 3 +Regulation of endoplasmic reticulum tubular network organization 0.5754980261511183 0.934135032640996 0.3502342428955454 1.0 1.0 5 Q9H2M9,Q9C0E8,Q15042 3 +Substrate dependent cell migration 0.5754086929429176 0.93375634864738 0.3504295910623718 1.0 1.0 5 Q9Y5K6,P06576,Q14247 3 +Negative regulation of response to endoplasmic reticulum stress 0.529774712365873 0.9334950827431072 0.3505644081343946 1.0 1.0 14 O00330,P10909,Q86TM6,Q96HY6 4 +Epithelial cell differentiation involved in kidney development 0.5329692066993695 0.9321803900570416 0.3512433080624064 1.0 1.0 7 P80723 1 +Cell differentiation involved in kidney development 0.5329692066993695 0.9321803900570416 0.3512433080624064 1.0 1.0 7 P80723 1 +Regulation of mda 5 signaling pathway 0.8895309313392232 0.9274589413314952 0.3536883001874562 1.0 1.0 2 O75179 1 +Mda 5 signaling pathway 0.8895309313392232 0.9274589413314952 0.3536883001874562 1.0 1.0 2 O75179 1 +Regulation of immune effector process 0.4151229635348263 0.9274431073764882 0.3536965178239066 1.0 1.0 36 Q07021,P01889,Q9NUQ9,Q08722,O75179,P04439,O15400 7 +Alcohol metabolic process 0.3831591136856143 0.9255907764286386 0.3546586885473188 1.0 1.0 79 Q9BY49,Q15392,P61457,Q16850,O75874,O94788,Q14534,P48449,P30837,P48735,O43837,P35610,Q8WTV0 13 +Detection of stimulus 0.5241854166917869 0.9246531548523612 0.3551463540605903 1.0 1.0 16 O00330,Q9UNS1,P04439,Q8WTV0,Q05397 5 +Cellular response to steroid hormone stimulus 0.341706167790749 0.9216955983430454 0.35668737716987 1.0 1.0 49 P20020,Q9H7B4,O95831,Q96HY6,Q9GZZ9 5 +Isotype switching to iga isotypes 0.6715402924175453 0.9193304864816292 0.3579227363978847 1.0 1.0 3 O96028,P43246 2 +B cell mediated immunity 0.5179420548128073 0.918699483105694 0.358252780268308 1.0 1.0 18 P10909,O60934,Q9UQ84,Q07021 4 +Regulation of rna binding 0.5305503272267178 0.918543770307494 0.3583342546857007 1.0 1.0 8 Q06787,Q9H1E3 2 +Protein exit from endoplasmic reticulum 0.5037528188356145 0.917987132281541 0.358625602587189 1.0 1.0 22 Q86TM6,Q9BUN8,Q9Y679,O15260,O15027 5 +Chaperone mediated protein complex assembly 0.5264428144531945 0.9166077762495995 0.3593482080298247 1.0 1.0 14 P10909,O15212 2 +Negative regulation of organelle assembly 0.5295204572490835 0.9160840730097272 0.3596228007291775 1.0 1.0 7 Q96PK6 1 +Positive regulation of vacuole organization 0.591386867360542 0.9144418592600116 0.3604847151091137 1.0 1.0 4 Q9H2M9 1 +Diencephalon development 0.529690152132588 0.9135802233566028 0.3609374620527359 1.0 1.0 9 O94788 1 +Regulation of protein lipidation 0.670005964812223 0.9135664276841616 0.3609447138946127 1.0 1.0 3 Q9H2M9 1 +Regulation of lipoprotein metabolic process 0.670005964812223 0.9135664276841616 0.3609447138946127 1.0 1.0 3 Q9H2M9 1 +Antigen processing and presentation 0.4985828929928168 0.9130294458913788 0.3612270550958978 1.0 1.0 23 Q9NZ08,P61026,P01889,O14920,P04439 5 +Positive regulation of mrna processing 0.5104808684259643 0.9127596753494596 0.3613689507788278 1.0 1.0 20 P38159,P62995,Q09161,Q9Y2W1,Q96E39,P98179,P19338,Q14011 8 +Regulation of pattern recognition receptor signaling pathway 0.5165772479984055 0.9113811682773796 0.3620945724519466 1.0 1.0 18 Q07021,O43657,Q9Y4E8,Q96RT1,O75179 5 +Negative regulation of actin filament bundle assembly 0.5278216072291437 0.908165333328346 0.3637908767076798 1.0 1.0 7 Q7Z460,P16949 2 +Aggrephagy 0.6681400884053079 0.9065643458998331 0.3646372233455275 1.0 1.0 3 Q5T8D3,O95817 2 +Negative regulation of leukocyte cell cell adhesion 0.5273740222976311 0.9051007511508534 0.36541201423565 1.0 1.0 11 Q5JRA6,Q96IZ0,Q92990 3 +Response to reactive oxygen species 0.4365456283350556 0.9038611634479256 0.3660690246306783 1.0 1.0 33 Q99720,O95831 2 +Mitochondrial fragmentation involved in apoptotic process 0.5681726533154727 0.9031425033827568 0.3664502685275055 1.0 1.0 5 Q9NT62 1 +Sensory system development 0.4285896517429437 0.9028398656303278 0.3666108897054951 1.0 1.0 34 Q13547,Q96EV8,P20020,P08670,O94788,Q9NP72,Q15042,Q15293,P54802 9 +Negative regulation of muscle cell differentiation 0.5271198969833135 0.901821293937792 0.3671518062607199 1.0 1.0 10 O75179,P67809 2 +Negative regulation of cell cell adhesion 0.5215887897869415 0.900637219880887 0.3677812383147065 1.0 1.0 15 Q92990,P35241,Q96IZ0,Q5JRA6,Q05397 5 +Positive regulation of histone ubiquitination 0.5877849760573889 0.8998641725333396 0.3681925384824258 1.0 1.0 4 Q5VTR2 1 +Modification of synaptic structure 0.526324717572499 0.8986482721029344 0.368840037926605 1.0 1.0 8 Q9UQB8 1 +Vocalization behavior 0.8810333106730115 0.898205335317034 0.3690760895087008 1.0 1.0 2 Q7Z406 1 +Positive regulation of neuron projection arborization 0.8810333106730076 0.898205335317021 0.3690760895087077 1.0 1.0 2 O14641 1 +Positive regulation of excitatory postsynaptic potential 0.8810333106729978 0.8982053353169869 0.3690760895087259 1.0 1.0 2 Q9UQB8 1 +Negative regulation of epithelial cell apoptotic process 0.5256795615192399 0.8981909481943183 0.3690837583247872 1.0 1.0 7 O00330,P09601 2 +Positive regulation of myeloid leukocyte differentiation 0.5861556143387568 0.8932809200602159 0.3717067530468623 1.0 1.0 4 O00165,P16220 2 +Microtubule nucleation 0.5200996935828874 0.8930093709727689 0.371852154338034 1.0 1.0 15 Q96P70,Q9BSJ2,Q9ULW0,Q7Z460,Q9HD47,P0DMV9,Q14203,Q08379,Q14008,Q96S59,Q14155 11 +Antifungal innate immune response 0.8793337865397697 0.892377220797966 0.3721907765164827 1.0 1.0 2 Q9Y4E8 1 +Positive regulation of supramolecular fiber organization 0.3533223067436977 0.8919638680033495 0.3724122994138645 1.0 1.0 42 Q8NBJ5,O60504,P62993,P09493,Q14247,Q7Z460,Q08722,P61586,O95429,P10909,Q9UQB8 11 +Maintenance of dna methylation 0.5852869710062638 0.8897741918891628 0.3735871470075687 1.0 1.0 4 Q96T88 1 +Insulin secretion involved in cellular response to glucose stimulus 0.5229013851816801 0.8893907054335667 0.3737931384202495 1.0 1.0 6 O00330 1 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.5229013851816801 0.8893907054335667 0.3737931384202495 1.0 1.0 6 O00330 1 +Protein methylation 0.3396784938083391 0.88627600847674 0.3754688139566386 1.0 1.0 50 O60725,Q9H7B4,Q5VTR2,Q03164 4 +Intracellular transport of virus 0.5640246330950388 0.8856502858309101 0.3758060052852485 1.0 1.0 5 Q06787 1 +Transport of virus 0.5640246330950388 0.8856502858309101 0.3758060052852485 1.0 1.0 5 Q06787 1 +Regulation of cellular response to hypoxia 0.5834114782104786 0.8822098912024976 0.3776633140163927 1.0 1.0 4 O94966,Q9Y4L1 2 +Establishment of cell polarity 0.3821844397482018 0.8813853343913167 0.3781092927059024 1.0 1.0 39 Q13308,P61026,Q9H6U6,Q9UNZ2,Q9NUQ9,Q4VCS5,Q05397,Q7Z460,P61586,Q13257,Q96L92,Q15334 12 +Positive regulation of protein polyubiquitination 0.5826423119942681 0.8791105179096721 0.3793413554282359 1.0 1.0 4 O75150 1 +Response to salt 0.6603196191771499 0.8773107172871257 0.3803178926279607 1.0 1.0 3 P09651,P52758 2 +Detection of biotic stimulus 0.5615507795987281 0.8752394299992637 0.3814436430957091 1.0 1.0 5 P04439,Q8WTV0 2 +Secretory granule localization 0.659606061372597 0.8746494705158898 0.3817646615497594 1.0 1.0 3 O60763 1 +Regulation of mitochondrial rna catabolic process 0.5613818111151568 0.8745289559384842 0.381830258304296 1.0 1.0 5 Q9GZT3 1 +Outer mitochondrial membrane organization 0.5603946920721314 0.8703799228984691 0.3840928148894935 1.0 1.0 5 O14737,P07900,Q9Y512,Q9NS69 4 +Regulation of clathrin dependent endocytosis 0.5602122507599514 0.8696133875458085 0.3845117191383518 1.0 1.0 5 Q9H3U1,Q13432,Q6P3W7 3 +Microtubule organizing center organization 0.3989388125272554 0.868347544662042 0.3852041016714125 1.0 1.0 37 Q9H6U6,Q14203,O43633,O75351,P53985,Q9C0F1,Q9UBK9,Q7Z460,Q68CZ6,Q14008,P06748,P43487,P53350,P24941,Q9UNZ2,Q9NZZ3,Q9Y3E7,Q08379,O75116,Q96PK6,Q9H6D7 21 +Nuclear transcribed mrna catabolic process nonsense mediated decay 0.5143805081987446 0.8637768961350518 0.3877104620425462 1.0 1.0 15 Q15477,Q9Y5S9,A2RRP1,Q99729,Q09161,Q9NPI6 6 +Positive regulation of receptor internalization 0.5587341177037739 0.863406413321442 0.3879140545389676 1.0 1.0 5 Q06787 1 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.5186236780674663 0.86105286705652 0.3892089265427909 1.0 1.0 10 O00330,Q86TM6,O95881,Q9Y4L1,O60313 5 +Oligodendrocyte development 0.5184997290822873 0.8604539540587901 0.3895388553080461 1.0 1.0 9 P10909,P18074 2 +O glycan processing 0.5579342150898975 0.8600500721272956 0.3897614415139969 1.0 1.0 5 Q10471,Q9H488,Q10472 3 +Phosphatidylcholine catabolic process 0.8694765465669464 0.8587322668019135 0.3904882442034711 1.0 1.0 2 Q8WTV0 1 +Regulation of protein dephosphorylation 0.4889413291353942 0.8569965378354792 0.3914467980180889 1.0 1.0 23 Q13526,O75116,O14920,P62942,Q92797,O43768,Q15435 7 +Double strand break repair via break induced replication 0.5173783459211667 0.8551503793339709 0.392467902350754 1.0 1.0 9 Q14566,P33991 2 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.508198334743473 0.8531292427998388 0.3935876363839528 1.0 1.0 17 Q86TM6,O00330,Q8IXB1,O95881,O95831,P46379 6 +Positive regulation of response to external stimulus 0.3418913371086516 0.8513553601307202 0.3945719811058021 1.0 1.0 54 Q8NHP6,O14920,Q08722,Q9Y4E8,Q8NE86,O75179,Q96PK6,Q8WXF1,Q05397 9 +Cellular response to oxygen levels 0.4051924134622898 0.8495764028149012 0.395560635872044 1.0 1.0 36 P55786,Q8N511,O95831 3 +L amino acid transport 0.5129624511646005 0.8486098098326318 0.3960984465422186 1.0 1.0 14 O60831,P08195,Q9Y619,Q96QD8,O75915,O75746,P30825 7 +Protein folding in endoplasmic reticulum 0.5149693151522268 0.8454265258179383 0.3978727395048798 1.0 1.0 8 Q8IXB1,P27824,P27797,Q13217,P07237 5 +Positive regulation of vascular associated smooth muscle cell proliferation 0.651198276351991 0.8433992915867645 0.3990051679965911 1.0 1.0 3 O95140 1 +Regulation of glycogen metabolic process 0.5125147131231254 0.8417409579570068 0.3999329668404536 1.0 1.0 6 P31751 1 +Regulation of glucan biosynthetic process 0.5125147131231254 0.8417409579570068 0.3999329668404536 1.0 1.0 6 P31751 1 +Positive regulation of protein targeting to membrane 0.5138773752339134 0.8403295159019474 0.4007236566040606 1.0 1.0 8 Q12965,P31751 2 +Activin receptor signaling pathway 0.6498946360377544 0.8385723337312573 0.4017093412259991 1.0 1.0 3 Q9Y2U8 1 +Regulation of activin receptor signaling pathway 0.6498946360377544 0.8385723337312573 0.4017093412259991 1.0 1.0 3 Q9Y2U8 1 +Cytoplasmic translational initiation 0.5000533358005986 0.8381197501045422 0.4019634517124086 1.0 1.0 19 Q15056,P55010,Q9BWF3,P23588 4 +Rna polyadenylation 0.4481145024919029 0.8371706844281712 0.4024966332079889 1.0 1.0 30 Q8N684,O75150,Q5VTR2,Q09161,Q6UN15,Q12849,Q92797,O00267,Q6PJT7 9 +Cellular response to vitamin d 0.5721174272401212 0.8368780348796823 0.402661128108511 1.0 1.0 4 P20020,Q8TB36 2 +Glutamate receptor signaling pathway 0.8630183548606313 0.836843435488982 0.4026805786862686 1.0 1.0 2 Q06787 1 +Dna methylation or demethylation 0.4927069594827183 0.8336836281677272 0.404459286208108 1.0 1.0 21 Q8NB78,Q8N2A8,Q96TA1,Q03164 4 +Regulation of neurotransmitter uptake 0.6480788847330878 0.8318578245444787 0.4054892001993071 1.0 1.0 3 P05556,P20337 2 +Histone methylation 0.3668344226912604 0.8310173276878895 0.4059638406776216 1.0 1.0 40 Q5VTR2,Q9H7B4,Q03164 3 +Peptidyl lysine methylation 0.4534602902803064 0.830946392775656 0.4060039138041695 1.0 1.0 29 Q9H7B4 1 +Acetyl coa biosynthetic process 0.5120773582058733 0.830135032918895 0.4064624418124087 1.0 1.0 9 O00330,P35610 2 +Endoplasmic reticulum tubular network organization 0.5117234190143611 0.8292594777990718 0.4069575953926094 1.0 1.0 11 P61026,Q9H2M9,Q9C0E8,Q9NP72,Q15042,Q8NHH9 6 +Natural killer cell mediated immunity 0.5106481560132818 0.8285614769434709 0.4073525941739988 1.0 1.0 7 P04439 1 +Response to wounding 0.3681271052811073 0.8284112121979903 0.4074376589080515 1.0 1.0 75 Q13308,O00330,P42785,P10586,Q96AY3,Q03001,Q5JRA6,Q8WTV0,Q05397 9 +Rna capping 0.6462531415516743 0.825116693105874 0.4093053433440139 1.0 1.0 3 Q09161 1 +Lipopolysaccharide mediated signaling pathway 0.5104006320776251 0.8241274325755792 0.4098671543954642 1.0 1.0 8 O95999,Q8WTV0 2 +Positive regulation of synaptic transmission glutamatergic 0.8585995921142091 0.8219417110510201 0.4111100721223208 1.0 1.0 2 Q15042 1 +Regulation of glutamate secretion 0.8585995921142091 0.8219417110510201 0.4111100721223208 1.0 1.0 2 Q15042 1 +Positive regulation of glutamate secretion 0.8585995921142091 0.8219417110510201 0.4111100721223208 1.0 1.0 2 Q15042 1 +Negative regulation of neuron projection development 0.4936487984683904 0.8201062859203454 0.4121555191086505 1.0 1.0 20 Q96EV8,P08670,O14976,P61586,Q9NQX7,Q9UL15,Q8N0X7 7 +Regulation of response to endoplasmic reticulum stress 0.4825012180566388 0.8197788620956132 0.412342183287119 1.0 1.0 23 O00330,Q86TM6,O95881,Q9Y4L1,P10909,O94966,Q96HY6,P46379 8 +Histone h4 acetylation 0.5016746254152848 0.8190029830651333 0.412784711631097 1.0 1.0 17 Q03164 1 +Embryonic brain development 0.5480736136842884 0.8188360396493343 0.4128799658200341 1.0 1.0 5 P62995 1 +Sensory organ development 0.34113655878997 0.8154771554236849 0.4147992357748062 1.0 1.0 56 Q13308,Q96EV8,Q13547,P20020,P08670,O94788,Q9NP72,Q15042,O14641,Q15293,P54802 11 +Histone h4 k20 methylation 0.6434930539749621 0.8149458651863439 0.4151032979482465 1.0 1.0 3 O96028 1 +Negative regulation of telomere capping 0.8562202583276566 0.8139438690923969 0.4156771076411298 1.0 1.0 2 O60934 1 +Positive regulation of filopodium assembly 0.5062102928812429 0.8129846213581425 0.4162268754164555 1.0 1.0 6 Q06787,Q9H6U6 2 +Negative regulation of amyloid precursor protein catabolic process 0.5082305577855488 0.8124460406829767 0.4165357368800852 1.0 1.0 11 P10909,O75298 2 +Amino acid betaine biosynthetic process 0.6426913602904555 0.8119962923487242 0.4167937589702175 1.0 1.0 3 P49419 1 +Rig i signaling pathway 0.5064159207328994 0.8061217171053477 0.4201726706604467 1.0 1.0 12 O75179,Q9Y4E8,Q07021 3 +Response to muramyl dipeptide 0.5445198541742063 0.8040607064550418 0.4213619162228279 1.0 1.0 5 P08670 1 +Morphogenesis of an epithelium 0.3385794526156619 0.8036754794525622 0.4215844189741662 1.0 1.0 55 Q13308,O00330,O95999,Q92990,P61026,O94788,Q7Z460,P61586,Q12849,Q9UNS1,O14641,P62993,P11233 13 +Positive regulation of muscle tissue development 0.5628861337032495 0.8001364886308001 0.4236317222774652 1.0 1.0 4 Q96TA1 1 +Viral protein processing 0.5049128446585115 0.798641832643248 0.4244981237968555 1.0 1.0 8 Q13724 1 +Spermatid differentiation 0.4951875002812483 0.7975223661846694 0.4251477184671457 1.0 1.0 18 Q8N2A8,Q96SI9,Q96KQ7,Q9GZT3,Q08J23 5 +Morphogenesis of embryonic epithelium 0.4780502321437284 0.7941706193003415 0.4270961102852804 1.0 1.0 23 Q13308,O00330,O94788,Q92990 4 +Regulation of adherens junction organization 0.8501019714479943 0.7934652118794735 0.4275068298822986 1.0 1.0 2 P35241 1 +Nucleosome assembly 0.4350176091330556 0.7930204820854837 0.4277658895546601 1.0 1.0 31 Q9NRF9,Q01105,Q9H7B4,Q9NRG0 4 +Cd8 positive alpha beta t cell activation 0.849762066621345 0.792331283072396 0.4281675355874434 1.0 1.0 2 P04439 1 +Regulation of cd8 positive alpha beta t cell activation 0.849762066621345 0.792331283072396 0.4281675355874434 1.0 1.0 2 P04439 1 +Positive regulation of cd8 positive alpha beta t cell activation 0.849762066621345 0.792331283072396 0.4281675355874434 1.0 1.0 2 P04439 1 +Muscle hypertrophy in response to stress 0.6369674150267097 0.7909997593686074 0.4289441319072642 1.0 1.0 3 P23634 1 +Metanephros morphogenesis 0.6367762993158311 0.790300661130898 0.4293522008081853 1.0 1.0 3 P80723 1 +Adenylate cyclase activating adrenergic receptor signaling pathway 0.8490822569680496 0.7900646409956487 0.4294900184610994 1.0 1.0 2 Q9Y4G8 1 +Positive regulation of camp dependent protein kinase activity 0.8490822569680496 0.7900646409956487 0.4294900184610994 1.0 1.0 2 Q9Y4G8 1 +Cytoplasm organization 0.6358678887308363 0.7869794770962323 0.4312938801730319 1.0 1.0 3 Q8N2A8 1 +Positive regulation by host of viral genome replication 0.5394247614104013 0.782956113310647 0.4336528841446911 1.0 1.0 5 Q9H1E3 1 +Regulation of protein polyubiquitination 0.5013395498698702 0.7821096425074906 0.4341501403977843 1.0 1.0 8 O75150,Q9Y263 2 +Regulation of cellular response to vascular endothelial growth factor stimulus 0.6340944547047063 0.7805042389290909 0.4350941334369809 1.0 1.0 3 Q12965 1 +Smooth muscle contraction 0.5012851748837048 0.7795220516959134 0.4356722527859806 1.0 1.0 9 P20020,Q14247,P61586,O00213,P23634 5 +Glycosylation 0.3791989573597961 0.7793027322768536 0.4358014055614883 1.0 1.0 38 Q8TCJ2,Q13724,Q08379,Q9HC07,P33908,Q96AA3,Q9NYU2 7 +Antigen processing and presentation of endogenous peptide antigen 0.5005349002025856 0.7783940246074578 0.4363367603494366 1.0 1.0 8 P04439,Q9NZ08 2 +Antigen processing and presentation of endogenous antigen 0.5005349002025856 0.7783940246074578 0.4363367603494366 1.0 1.0 8 P04439,Q9NZ08 2 +Regulation of t cell receptor signaling pathway 0.4984738217654455 0.7778936632167059 0.4366317043002885 1.0 1.0 6 Q96IZ0 1 +Regulation of antigen receptor mediated signaling pathway 0.4984738217654455 0.7778936632167059 0.4366317043002885 1.0 1.0 6 Q96IZ0 1 +Neutrophil chemotaxis 0.5007439777288931 0.7765708223119986 0.4374120215304544 1.0 1.0 11 O00429,Q07021,Q8NHP6,Q8NE86,P35613,Q00013 6 +Regulation of defense response 0.3637758676840462 0.7724628349312842 0.4398403506780775 1.0 1.0 76 Q9NZ08,P28070,Q9UIV1,P01889,O14920,O43657,Q08722,Q9Y4E8,P19474,P04439,Q96PK6,Q8WXF1 12 +Regulation of telomere capping 0.4961757131042175 0.7675157978341712 0.4427749041118549 1.0 1.0 6 O60934 1 +Extracellular vesicle biogenesis 0.4986969537180558 0.7663993773702635 0.4434387031744726 1.0 1.0 10 O14964,Q92783,Q9Y3E7,Q9UN37,O75351 5 +Locomotor rhythm 0.6300605621881648 0.765818440362752 0.4437843403300809 1.0 1.0 3 P54802 1 +Neuropeptide signaling pathway 0.6298571592404354 0.765079544595258 0.4442241796259574 1.0 1.0 3 Q9Y4G8 1 +Nitric oxide synthase biosynthetic process 0.5539160391108108 0.7647395776765753 0.4444266338165952 1.0 1.0 4 P43490 1 +Positive regulation of nitric oxide synthase biosynthetic process 0.5539160391108108 0.7647395776765753 0.4444266338165952 1.0 1.0 4 P43490 1 +Snrna transport 0.6295123137582419 0.763827194511701 0.4449702286210484 1.0 1.0 3 Q09161 1 +Maintenance of synapse structure 0.5535430181883614 0.7632746363800513 0.4452996251516876 1.0 1.0 4 Q15334 1 +Regulation of protein targeting to membrane 0.4977662389512907 0.7631213061551159 0.4453910545438215 1.0 1.0 9 Q12965,P31751 2 +Regulation of myotube differentiation 0.4950964264249142 0.762649613557711 0.4456723875457022 1.0 1.0 6 Q13547,Q9BYT8,Q96TA1 3 +G quadruplex dna unwinding 0.5533113781785322 0.7623652253988278 0.4458420549245145 1.0 1.0 4 P51530 1 +Positive regulation of cytoplasmic translation 0.4975717698864907 0.7614423347176488 0.4463929094395993 1.0 1.0 11 P11940,Q9H074,P67809 3 +Protein quality control for misfolded or incompletely synthesized proteins 0.4962491962947731 0.760250110567804 0.4471050967906373 1.0 1.0 13 Q9Y679,Q9BUN8,P46379,Q9NYU2 4 +Tissue morphogenesis 0.3423784496884788 0.7589518445488141 0.4478813638554428 1.0 1.0 61 O94788,O60313,P11233,Q13308,O00330,Q92990,Q7Z460,P62942,P10644,O14641,P61026,Q13043,P61586,Q12849,Q9UNS1,P62993,P42224,O95999,P09493 19 +Digestive system development 0.4966347407129414 0.7569823789532051 0.4490604194117873 1.0 1.0 11 O94788 1 +Urogenital system development 0.3183667904436041 0.7556866253454297 0.4498371048439837 1.0 1.0 44 Q13308,P80723,O94788,P07602,P35610 5 +Actin filament based transport 0.4952961897687657 0.7542712160735442 0.4506863823817011 1.0 1.0 8 Q9UH99 1 +Regulation of response to cytokine stimulus 0.4815003875585961 0.7539944079171256 0.4508525796069542 1.0 1.0 20 O14920,Q9UIV1 2 +Actin filament bundle organization 0.3386666830492738 0.752963357423821 0.4514719335285593 1.0 1.0 42 Q9UQB8,O60504,P35241,P09493,Q7Z460,Q08722,P16949,P61586,Q96IZ0,O95429,O75116,P35611,P29966 13 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.6259775586535232 0.7510167541629904 0.4526425728087264 1.0 1.0 3 Q04637,P40763 2 +Magnesium ion homeostasis 0.6252975178510872 0.7485578140663794 0.4541237667111575 1.0 1.0 3 Q6P4Q7,Q8NE01 2 +Regulation of erad pathway 0.4918707610956944 0.7481363644516629 0.4543779097346991 1.0 1.0 6 O94966 1 +Carnitine metabolic process 0.5301969013817355 0.7449909490957236 0.4562771914462984 1.0 1.0 5 P23786 1 +Positive regulation of protein localization to early endosome 0.5292616590856423 0.7411630513578278 0.4585945834541043 1.0 1.0 5 P35241 1 +Positive regulation of double strand break repair via homologous recombination 0.4912979947743053 0.7361355729830219 0.4616481959264011 1.0 1.0 13 Q9UBU8,Q9UNS1,P35637 3 +Mrna 3 end processing 0.3982429759128302 0.7349203094521869 0.4623880286955457 1.0 1.0 35 Q5VT52,Q8N684,O75150,Q5VTR2,Q09161,Q6UN15,Q12849,Q92797,O00267,Q6PJT7 10 +Negative regulation of translational initiation 0.4902182722364964 0.7310079881476176 0.4647742737233735 1.0 1.0 8 P60228,Q9BPZ3,P12270,Q9BWF3,Q06787 5 +Cellular response to muramyl dipeptide 0.6200373780867432 0.7296011523529712 0.465634017637389 1.0 1.0 3 P08670 1 +Endothelial cell proliferation 0.4841504680752788 0.7282796251968469 0.4664424320802571 1.0 1.0 17 O94788 1 +Epoxide metabolic process 0.830047586675732 0.7272936555405384 0.4670460838617338 1.0 1.0 2 P34913 1 +Organelle fusion 0.3155679287374605 0.7272599917158361 0.4670667019068335 1.0 1.0 44 Q8NAN2,Q8N2A8,Q9UJZ1,Q8TB36,Q96E52,Q9H300,Q9H270,Q9NX63,Q9Y3E7,O60343,Q9Y6C9,O60763,O60313,O60499,O15400,P31751 16 +Regulation of immune response 0.4001853546495589 0.726811005172752 0.4673417404519295 1.0 1.0 109 P28070,P01889,P19474,O15400,Q9NZ08,Q9UIV1,O14920,P62942,P10909,O75179,Q8WXF1,Q07021,O43657,Q08722,Q96IZ0,Q9NUQ9,Q9Y4E8,Q96RT1,P04439,Q96PK6,Q05397 21 +Pathway restricted smad protein phosphorylation 0.5441975343771916 0.7267705556970003 0.4673665232530921 1.0 1.0 4 Q9Y4E8 1 +Regulation of protein modification by small protein conjugation or removal 0.3639637229513035 0.7234526827880186 0.4694018144179148 1.0 1.0 80 Q13526,Q92990,Q96DY7,O75150,Q9BUN8,Q5VTR2,Q9UL15,Q92564,P62942,P19474,Q13257,Q9NW82,Q9Y263 13 +Cytokine production involved in immune response 0.4886851775737206 0.7210608422919457 0.4708720817891354 1.0 1.0 9 P04439,O95999 2 +Positive regulation of protein dephosphorylation 0.4889826495884761 0.7208679667263196 0.4709907532751225 1.0 1.0 10 Q15435,Q13526 2 +Regulation of stress granule assembly 0.6167970078204835 0.7179810028246776 0.4727690003363598 1.0 1.0 3 Q9UN86,Q13283 2 +Neuron cellular homeostasis 0.4860472678461173 0.7163845348237181 0.4737539415940599 1.0 1.0 7 P78559,P20020,P23634 3 +Positive regulation of cytokine production involved in immune response 0.4869064394739421 0.7159034149059026 0.4740509896988598 1.0 1.0 8 P04439 1 +Endocrine system development 0.4859866431967409 0.7146551802645568 0.474822138940711 1.0 1.0 14 O94788 1 +Inclusion body assembly 0.4870180961722303 0.7133839264361854 0.4756082166166724 1.0 1.0 9 P10909,Q9UL15 2 +Positive regulation of translation in response to endoplasmic reticulum stress 0.6154369262155795 0.7131171979985663 0.4757732382401831 1.0 1.0 3 Q04637,Q13217 2 +Positive regulation of translation in response to stress 0.6154369262155795 0.7131171979985663 0.4757732382401831 1.0 1.0 3 Q04637,Q13217 2 +Myeloid leukocyte cytokine production 0.4852726753276467 0.712897076474735 0.4759094483791073 1.0 1.0 7 Q9NY93,O95999,P14174,P09601,Q9H2U1 5 +Positive regulation of cell cell adhesion mediated by cadherin 0.6153068584148382 0.7126524864600234 0.4760608245748532 1.0 1.0 3 P55196 1 +Erad pathway 0.3874690232822808 0.7123736808047327 0.4762334089350708 1.0 1.0 36 Q86TM6,Q8TCJ2,Q8IXB1,Q9BUN8,O94966,Q9NYU2 6 +Nucleosome mobilization 0.4864814530429903 0.7092216638999947 0.4781869317455864 1.0 1.0 10 Q9NRG0 1 +Rna mediated gene silencing by inhibition of translation 0.5213411756398985 0.7089035301098318 0.4783843443111097 1.0 1.0 5 Q9BWF3,Q04637,P40763 3 +Regulation of lysosomal lumen ph 0.4843822174559454 0.7088917822119154 0.4783916351238568 1.0 1.0 7 Q9HC07 1 +Kidney epithelium development 0.486195635251519 0.7087441402950112 0.478483267719638 1.0 1.0 12 P35610,P80723 2 +Notch signaling pathway 0.4818393946670876 0.7072995649541824 0.4793803358454394 1.0 1.0 16 Q96T58,Q9NWT6,Q96TA1,P09525,Q15334 5 +Negative regulation of i kappab kinase nf kappab signaling 0.4826395399974773 0.7068713962399632 0.4796464009452874 1.0 1.0 6 Q13547,P61586 2 +Anaphase promoting complex dependent catabolic process 0.4860019813429108 0.7066783180175037 0.4797664065804965 1.0 1.0 11 P24941,Q13042,Q9UJX3,Q16763,Q9UJX5,P53350 6 +Positive regulation of histone methylation 0.4777597724059421 0.7062853664340475 0.4800106918682503 1.0 1.0 18 Q5VTR2,Q03164,O15294,O60885,Q13573 5 +Ubiquitin dependent erad pathway 0.4088064214112459 0.7055456214709802 0.4804707513438495 1.0 1.0 33 Q86TM6,Q8TCJ2,Q8IXB1,Q9BUN8,O94966 5 +Response to arsenic containing substance 0.485117646413612 0.7036109175977645 0.4816751104671046 1.0 1.0 12 Q96QD8 1 +Dna double strand break processing 0.5195536607964857 0.7016641659663638 0.4828886252927031 1.0 1.0 5 Q9NW82 1 +Negative regulation of cell population proliferation 0.3741267025333281 0.6988827902901465 0.4846252834441173 1.0 1.0 90 Q96G23,P52756,Q96TA1,O94788,Q01085,O43815,P09601,P02545,P50402,O00330,O14964,Q15392,P98175,P52758,Q9UIV1,Q96DY7,Q92990,Q15637,P10644,P25054,Q9Y4G8,Q99627,Q13043,P61586,Q96IZ0,P21359,Q9UPY3,Q32P28,P42771,P42224,P09493,Q12797,O95140,P41240,P17096,P35221 36 +Regulation of sequestering of triglyceride 0.6102213505404673 0.6945422872519077 0.4873421910159057 1.0 1.0 3 Q9BZF1 1 +Cytoskeleton dependent cytokinesis 0.3137073998943253 0.6941596913205552 0.4875820680463243 1.0 1.0 45 Q13432,P53990,Q6DKK2,Q8WUX9,O95235,Q12768,Q01082,Q16181,Q9Y3E7,Q02241,O95630,P16949,P61586,O75116,P25054,O75935,Q14141 17 +Establishment or maintenance of cell polarity 0.3328922505544872 0.6918003052593613 0.489062744918681 1.0 1.0 59 Q13308,P61026,Q9H6U6,Q9NUQ9,Q4VCS5,Q03001,Q13257,Q96RT1,Q96L92,Q05397 10 +Mrna cleavage involved in mrna processing 0.4814773452805215 0.6912664176929739 0.4893981317926252 1.0 1.0 8 Q09161,Q6UN15 2 +Segmentation 0.4810036514873748 0.6903130891874809 0.4899973183135273 1.0 1.0 14 Q8N2A8,O94788,P80723 3 +Histone h3 acetylation 0.4818147672795892 0.6875838408464282 0.4917148869870824 1.0 1.0 10 Q03164 1 +Cell killing 0.4779019222243305 0.6875350443273145 0.4917456249551226 1.0 1.0 16 Q9NUQ9,O15400,P04439 3 +Positive regulation of actin filament polymerization 0.4817468544842062 0.6867172096622647 0.4922609499041401 1.0 1.0 11 P62993,Q9UQB8,O95429,Q14247 4 +Positive regulation of protein export from nucleus 0.4815775766336213 0.6859252805521465 0.4927602274214995 1.0 1.0 11 P50402,P12270,Q9C0E2,Q05D32 4 +Rrna transport 0.6076164569874349 0.6853120053589059 0.4931470576617385 1.0 1.0 3 P06748,Q16762 2 +Mast cell cytokine production 0.8167912984364389 0.6844427174279224 0.4936956494100035 1.0 1.0 2 O95999 1 +Response to cisplatin 0.8167912984364281 0.6844427174278869 0.4936956494100259 1.0 1.0 2 Q9UNS1 1 +Positive regulation of hormone secretion 0.4805379807056109 0.684182604838581 0.4938598651925092 1.0 1.0 13 O00330 1 +Hippo signaling 0.4772892376105959 0.6831539837771369 0.4945095464467479 1.0 1.0 6 Q4VCS5 1 +Positive regulation of glucose transmembrane transport 0.5145279969333364 0.6813964883805483 0.4956206442684143 1.0 1.0 5 P31751 1 +Positive regulation of glucose import 0.5145279969333364 0.6813964883805483 0.4956206442684143 1.0 1.0 5 P31751 1 +Regulation of mrna 3 end processing 0.4743399906565451 0.6782268041099434 0.4976278999743921 1.0 1.0 17 O75150,Q5VTR2,Q09161,O00267,Q6PJT7 5 +Positive regulation of lymphocyte mediated immunity 0.477142241981739 0.6767941446011343 0.4985365737726797 1.0 1.0 15 Q9NUQ9,O15400,P04439 3 +Ribonucleoprotein complex localization 0.4758207295001431 0.6766717965888855 0.4986142146791548 1.0 1.0 6 P12270,Q08J23 2 +Actin cytoskeleton reorganization 0.4534513651926503 0.6763959446176749 0.4987892913491509 1.0 1.0 24 Q13308,Q96EV8,Q9H6U6,Q14247,Q9Y5K6,Q8NE86,P62993,P11233,Q9UQB8 9 +Regulation of toll like receptor 3 signaling pathway 0.6045562733764085 0.6745097279850931 0.4999873031389013 1.0 1.0 3 Q9UMX0,O75955 2 +Asymmetric cell division 0.4751956817239404 0.6739164829855353 0.5003644122066337 1.0 1.0 6 Q08379 1 +Integrin mediated signaling pathway 0.4729260291326034 0.671063651720917 0.5021799812545522 1.0 1.0 17 Q08722,Q05397,Q03001 3 +Cellular response to ketone 0.47434273260709 0.6697543285194824 0.5030144123280951 1.0 1.0 16 Q9H7B4,O95831 2 +Female meiosis chromosome segregation 0.6030791337138479 0.6693118375270053 0.5032965771786229 1.0 1.0 3 P33981 1 +Rab protein signal transduction 0.510778831709193 0.6663630061147703 0.5051791022449836 1.0 1.0 5 Q9UL25,P51151 2 +Positive regulation of endocytosis 0.4677224491620403 0.6662623246218414 0.5052434424277035 1.0 1.0 19 Q9UL25,Q06787,P10909,P61978 4 +Histone serine phosphorylation 0.6021225846757358 0.6659516180409227 0.5054420256749104 1.0 1.0 3 Q13043 1 +Meiotic chromosome condensation 0.5273117774303286 0.6618846206596227 0.5080451688031744 1.0 1.0 4 Q9NTJ3 1 +Regulation of polysaccharide metabolic process 0.4744052039448657 0.6594225127352321 0.5096244894753879 1.0 1.0 8 P31751 1 +Negative regulation of muscle cell apoptotic process 0.5262640011352998 0.657908634562734 0.510596841970284 1.0 1.0 4 P09601 1 +Regulation of protein localization to centrosome 0.5260204116701204 0.6569851850418441 0.5111904424767555 1.0 1.0 4 P25054,Q9UNZ2 2 +Membrane depolarization during action potential 0.5994559673580458 0.6566085051916685 0.5114326786612049 1.0 1.0 3 Q12955,Q9HD47 2 +Positive regulation of sister chromatid cohesion 0.5076473632207681 0.6538656044113834 0.5131983954292112 1.0 1.0 5 P23246,Q96MF7 2 +Regulation of protein kinase a signaling 0.5984359061543769 0.6530440909616998 0.5137278542127701 1.0 1.0 3 P14174,O00170 2 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.470306286458565 0.6524425356634537 0.5141157319529204 1.0 1.0 6 P25054,O00410,P42771 3 +Response to hydroxyurea 0.5071911338788682 0.6520494640344026 0.5143692634537591 1.0 1.0 5 Q06787 1 +Zinc ion homeostasis 0.5068496509833416 0.6506908839649048 0.5152460489883133 1.0 1.0 5 Q8TAD4 1 +Escrt complex disassembly 0.4731552787947307 0.6501487859912919 0.5155961187338705 1.0 1.0 9 P53990,Q9NP79,Q8WUX9,Q9NZZ3,Q9UN37,O75351 6 +Myotube differentiation 0.4701962922961013 0.6491478081046659 0.5162428428870363 1.0 1.0 16 Q96TA1,Q9H7B4,Q9P2K5 3 +Positive regulation of fatty acid metabolic process 0.5239311070531278 0.6490786789769348 0.5162875222098553 1.0 1.0 4 P31751,Q92604 2 +Negative regulation of exocytosis 0.4707062023314183 0.6479302003656489 0.5170300965671417 1.0 1.0 7 Q06787,P09601 2 +Zinc ion transport 0.8052345343303886 0.6477314224592158 0.5171586769710099 1.0 1.0 2 Q8TAD4 1 +Positive regulation of immune response 0.3404353698705626 0.6472419057069192 0.517475393719371 1.0 1.0 68 P61088,Q15233,P01889,P12956,O15400,P61086,O14920,Q13177,P10909,P43243,Q8WXF1,O60828,P46379,Q9UJZ1,Q07021,Q08722,Q96IZ0,O96028,P23246,O95999,Q9NUQ9,Q9NUD5,Q07666,P41240,P04439,Q96PK6,Q05397 27 +Regulation of chemotaxis 0.4480152502757952 0.6454426921434974 0.5186403447418586 1.0 1.0 24 Q8NHP6,Q9NUQ9,Q8NE86 3 +Phosphatidylserine metabolic process 0.5053473401019806 0.6447220046235925 0.5191073538036628 1.0 1.0 5 Q9BZF1 1 +Regulation of phospholipid metabolic process 0.4718972701849056 0.6444680596760024 0.5192719631007903 1.0 1.0 9 O75874 1 +Positive regulation of cellular protein catabolic process 0.3114878551619164 0.6438275908424793 0.519687240150648 1.0 1.0 47 P10909,P35241,O75150,Q9Y5A7,Q96JB5,Q06787,Q96HY6,Q05397 8 +Positive regulation of metaphase anaphase transition of cell cycle 0.4722892098438753 0.6438186155444573 0.5196930609098067 1.0 1.0 10 Q15398,Q96MF7,Q13042,Q9UJX3,Q9UJX5 5 +Glial cell development 0.4607343590639032 0.6430059995258036 0.5202202069512749 1.0 1.0 20 P08670,Q9UPY3,P18074,P10909,P31751 5 +Negative regulation of androgen receptor signaling pathway 0.5953183378128749 0.642183973144154 0.5207537378369418 1.0 1.0 3 Q13547 1 +Regulation of protein targeting 0.4386554237092224 0.6400573433841742 0.5221353197292453 1.0 1.0 26 P27105,Q9H300,P55786,Q9H270,Q12965,O95429,P31751 7 +Actin filament polymerization 0.3449114139301185 0.6398382130853862 0.5222777864724235 1.0 1.0 40 P35241,Q14019,Q9NUQ9,Q12768,Q01082,Q14247,P35611,P61586,O95429,O15020,P62993,Q9UQB8 12 +Establishment of spindle orientation 0.4715593991317186 0.6393737777124917 0.5225798034229334 1.0 1.0 11 P05556,Q9UNZ2,Q7Z460,Q14203,Q13257,Q15334 6 +Negative regulation of cell adhesion 0.4286187165199146 0.6376771015022632 0.5236838944257747 1.0 1.0 28 Q92990,P35241,Q9H6U6,Q5JRA6,P61586,Q96IZ0,P21359,P10644,P06576,Q13951,P52565,Q05397 12 +Positive regulation of chromosome separation 0.470264391265012 0.6334041656011021 0.5264697454504346 1.0 1.0 11 Q15398,Q96MF7,Q13042,Q9UJX3,Q9UJX5 5 +Protein localization to early endosome 0.465884284006763 0.6331479626280211 0.526637023827464 1.0 1.0 6 Q14160,P35241,O75116 3 +Negative regulation of microtubule polymerization or depolymerization 0.4666400927260116 0.6315724168892298 0.5276663152163947 1.0 1.0 16 P04350,Q7Z460,P16949,O15344,P25054,Q14155 6 +Positive regulation of synaptic transmission 0.4664541475284899 0.6306560224682238 0.5282654597795209 1.0 1.0 16 Q96EV8,Q9BPZ3,P21359,Q15042,Q92542,P33176,Q06787,Q15334 8 +Negative regulation of rho protein signal transduction 0.5189186441450105 0.6302154999543133 0.5285535995198527 1.0 1.0 4 P05556,P16949 2 +Establishment of epithelial cell apical basal polarity 0.5015024512461994 0.6295065949596435 0.529017452516134 1.0 1.0 5 Q13308 1 +Negative regulation of golgi to plasma membrane protein transport 0.5915361543622875 0.6290783693417289 0.5292977507984256 1.0 1.0 3 Q9HD26 1 +Inorganic ion import across plasma membrane 0.4663990045094647 0.6289652692432239 0.5293717939221525 1.0 1.0 7 P23634,P05026 2 +Transport along microtubule 0.3141266097829334 0.6285865315578618 0.5296197800775704 1.0 1.0 50 P46821,Q66K74,Q9BW83,Q92572,O43805,Q9UL25,Q9Y678,O60313,Q96EV8,Q9UBK9,Q03001,A0AVF1,O94901,P33176,Q8TD16,O95817,P23246,P78559,Q00577 19 +Microtubule based transport 0.3141266097829334 0.6285865315578618 0.5296197800775704 1.0 1.0 50 P46821,Q66K74,Q9BW83,Q92572,O43805,Q9UL25,Q9Y678,O60313,Q96EV8,Q9UBK9,Q03001,A0AVF1,O94901,P33176,Q8TD16,O95817,P23246,P78559,Q00577 19 +Substrate dependent cell migration cell extension 0.7991162474507151 0.6285581671675868 0.5296383546123171 1.0 1.0 2 Q14247 1 +Response to vitamin 0.4691110172949503 0.6282258827721492 0.5298559770428246 1.0 1.0 12 O00330,O94788 2 +Embryonic organ development 0.3083648486575337 0.626709607222123 0.5308496051655878 1.0 1.0 46 Q13308,Q68CQ4,P62995,O94788,Q03164,O14641,P54802 7 +Regulation of vascular associated smooth muscle contraction 0.7980965329707567 0.6253810416804003 0.5317210018664149 1.0 1.0 2 P20020 1 +Negative regulation of vascular associated smooth muscle cell migration 0.7980965329707568 0.6253810416804 0.5317210018664151 1.0 1.0 2 P09493 1 +Cellular aldehyde metabolic process 0.4569694607544311 0.6232182523246586 0.5331411089230791 1.0 1.0 20 O75874,O94788,P48735 3 +Positive regulation of dephosphorylation 0.4671305864586876 0.619006669698452 0.5359119650583943 1.0 1.0 11 Q15435,Q13526 2 +Cardiac ventricle morphogenesis 0.4621434267064807 0.6169248125352947 0.5372843198212376 1.0 1.0 6 P09493 1 +Protein demannosylation 0.4981716565076681 0.6163986760447608 0.5376314269475124 1.0 1.0 5 Q86TM6,Q9NYU2 2 +Positive regulation of chromatin organization 0.4646898773451913 0.6161862839736897 0.5377715799070377 1.0 1.0 8 P24941,Q8NEY8 2 +Establishment of epithelial cell polarity 0.4634563927903597 0.6160795276340794 0.5378420330469025 1.0 1.0 7 Q13308,Q7Z460 2 +Gpi anchor metabolic process 0.4619188217828496 0.6159537614164322 0.5379250375750098 1.0 1.0 6 Q92643 1 +Glycerophospholipid catabolic process 0.4632917789089215 0.615360433158542 0.5383167153926165 1.0 1.0 7 Q8NCC3,Q8WTV0 2 +Aromatic amino acid transport 0.7946974847042841 0.6148295402709955 0.5386672985743006 1.0 1.0 2 P08195 1 +Ornithine transport 0.7946974847042738 0.6148295402709639 0.5386672985743215 1.0 1.0 2 Q9Y619 1 +Face development 0.4651090634773402 0.6139976125120756 0.5392169048814908 1.0 1.0 9 O94788 1 +Presynapse organization 0.5868752125127559 0.6130365998002281 0.5398521396471061 1.0 1.0 3 O95295,Q04637 2 +Regulation of leukocyte migration 0.4420320966001314 0.611670870662231 0.5407555381646887 1.0 1.0 24 Q07021,Q8NHP6,Q08722,Q8NE86,Q5JRA6,P09601,O00429,Q05397 8 +Foam cell differentiation 0.7933378653976677 0.610625921356116 0.5414472580545318 1.0 1.0 2 P35610 1 +Protein localization to adherens junction 0.5136054421768629 0.6103899788491173 0.5416035048576346 1.0 1.0 4 P18206,Q14160,Q07157 3 +Neuronal action potential 0.4958297807620176 0.6072245764157557 0.5437018844676662 1.0 1.0 5 Q06787 1 +Protein polymerization 0.3480135008083808 0.6069538027900887 0.5438815708741855 1.0 1.0 77 P46821,P35241,Q12768,Q01082,Q14203,P61086,Q14155,Q9BSJ2,Q14019,Q7Z460,Q9UQB8,P35611,P52907,Q13526,Q9Y3E7,Q14247,P16949,P61586,Q08379,O15020,P62993,O00429,Q9NUQ9,P04350,Q13813,O95429 26 +Positive regulation of chemokine production 0.4956823353074442 0.6066481579962495 0.5440844334033168 1.0 1.0 5 P14174,P19525,P09601 3 +Regulation of amyloid precursor protein catabolic process 0.4600546959477944 0.6065232774734187 0.5441673299158856 1.0 1.0 17 P10909,O75298,P62942 3 +I kappab kinase nf kappab signaling 0.3047809840508318 0.6050878572353392 0.5451206219891822 1.0 1.0 45 Q13547,P42224,O95999,O60885,O14920,O43657,Q86UE4,P62942,P61586,P19474,O75116,O75179,Q99584,P09601,Q96HY6 15 +Cardiac muscle tissue morphogenesis 0.4950522315975958 0.6041864530651344 0.5457196865167444 1.0 1.0 5 P09493 1 +Ventricular cardiac muscle tissue morphogenesis 0.4950522315975958 0.6041864530651344 0.5457196865167444 1.0 1.0 5 P09493 1 +Muscle organ morphogenesis 0.4950522315975958 0.6041864530651344 0.5457196865167444 1.0 1.0 5 P09493 1 +Regulation of protein k63 linked ubiquitination 0.4579190809551655 0.5987202941479707 0.5493594217223476 1.0 1.0 6 Q9Y263 1 +Positive regulation of nuclear division 0.4618699560262041 0.5957993733648944 0.5513092624037785 1.0 1.0 13 Q15398,P37198,Q8WWQ0,Q96MF7,Q13042,Q9UJX3,Q9UJX5 7 +Positive regulation of cellular amide metabolic process 0.3244174745972403 0.5955901340471592 0.5514490691638869 1.0 1.0 60 Q71RC2,Q07021,P08670,P51114,Q14011,P98179,P10909,Q06787,Q9H074,P67809 10 +Amino acid transmembrane transport 0.46043993356571 0.5955766214557203 0.5514580984275197 1.0 1.0 15 O60831,P08195,Q9Y619,Q96QD8,O75915,O75746,P30825 7 +Response to angiotensin 0.5804148248895054 0.5910090822395326 0.5545143355942062 1.0 1.0 3 Q13464,O75116 2 +Angiotensin activated signaling pathway 0.5804148248895054 0.5910090822395326 0.5545143355942062 1.0 1.0 3 Q13464,O75116 2 +Regulation of fc receptor mediated stimulatory signaling pathway 0.786539768864702 0.5897571402206032 0.5553534807782314 1.0 1.0 2 Q08722 1 +Negative regulation of vascular associated smooth muscle cell proliferation 0.4910323659647666 0.5885437123770502 0.5561674023863667 1.0 1.0 5 P09601,P09493 2 +Glycolipid transport 0.5074207955478065 0.5875447569494288 0.5568379004198798 1.0 1.0 4 Q96AA3 1 +Actin polymerization or depolymerization 0.3029499459273593 0.5870308074490547 0.5571830162785589 1.0 1.0 45 P35241,Q14019,Q9NUQ9,Q12768,Q01082,Q14247,P35611,P61586,O95429,O15020,P62993,Q9UQB8 12 +Export across plasma membrane 0.4586727831472073 0.5854101439862098 0.558271969582008 1.0 1.0 9 P05026 1 +Protein localization to cytoskeleton 0.4571597895806576 0.5851981961112958 0.5584144576883245 1.0 1.0 16 Q14789,Q9UNZ2,Q96JM3,O15344,P25054,P78559 6 +Protein k48 linked deubiquitination 0.4576178114388174 0.5851248667116845 0.558463759619533 1.0 1.0 8 O94966 1 +Positive regulation of dna binding 0.4579110762716627 0.5834668921653613 0.5595790384425263 1.0 1.0 15 O00330,Q96TA1,P18074 3 +Metanephric tubule development 0.5060263016127472 0.5824296387911325 0.560277322367885 1.0 1.0 4 P35610 1 +Dna replication initiation 0.4429249290909866 0.5789195947705189 0.5626434279296597 1.0 1.0 22 Q96S55,P24941,Q13416,O60934,Q9Y619,Q14566,P33991 7 +Positive regulation of cytoskeleton organization 0.3062707829700934 0.5786355482153723 0.5628351132474849 1.0 1.0 48 P46821,P62993,O60504,P09493,Q9H6U6,Q9UHV9,Q14247,Q7Z460,Q08722,P61586,Q14203,O95429,O75116,O00165,Q9UQB8 15 +Granulocyte chemotaxis 0.456725412240991 0.5778077707306807 0.5633939083508532 1.0 1.0 15 Q8NHP6,Q05397,Q07021,Q8NE86 4 +Negative regulation of protein import into nucleus 0.487945768455621 0.5766076303679422 0.5642045434718639 1.0 1.0 5 Q9ULC3,P61960 2 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4572352050188092 0.5764975349472015 0.56427893556475 1.0 1.0 14 O95831,Q9BXK5 2 +Regulation of response to external stimulus 0.3911614439749937 0.5762294592186724 0.5644600955821444 1.0 1.0 115 P28070,P01889,P19474,Q9UMX5,Q9NZ08,Q9UIV1,Q8NHP6,O14920,O75179,P80303,Q8WXF1,P10586,O43657,Q08722,Q9NUQ9,Q9Y4E8,Q8NE86,P04439,Q96PK6,Q05397 20 +Positive regulation of dendritic spine development 0.457419775089984 0.5748561059576943 0.565388617987773 1.0 1.0 11 Q9UQB8 1 +Monocarboxylic acid biosynthetic process 0.3614630142097745 0.5729122230785395 0.5667041280645391 1.0 1.0 37 Q9BY49,O94788 2 +Positive regulation of dna replication 0.4563894909934971 0.5725279730549246 0.566964340389374 1.0 1.0 14 P24941,Q9UJZ1,P51530,O95785 4 +Regulation of lymphocyte mediated immunity 0.4512107840088575 0.5711539856629616 0.5678952664344985 1.0 1.0 18 Q9NUQ9,O15400,P04439 3 +Negative regulation of schwann cell proliferation 0.7800815771583791 0.5701697095536132 0.568562598388717 1.0 1.0 2 Q9UPY3 1 +Schwann cell proliferation 0.7800815771583791 0.5701697095536132 0.568562598388717 1.0 1.0 2 Q9UPY3 1 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.5025144780508729 0.5696086828977858 0.5689431379751229 1.0 1.0 4 Q9Y6G9,Q13257 2 +Myeloid leukocyte migration 0.4344503734466423 0.5693698791912345 0.5691051533971025 1.0 1.0 24 Q8NHP6,Q08722,Q05397,Q8NE86 4 +Antibacterial humoral response 0.779741672331735 0.569145400968888 0.5692574698392288 1.0 1.0 2 P04439 1 +Smoothened signaling pathway 0.4487308263788967 0.5686156082710722 0.5696170301474823 1.0 1.0 19 O00330,O43805 2 +Regulation of binding 0.3591499430992974 0.5685531684626316 0.5696594140050348 1.0 1.0 89 O00330,Q96EV8,Q13526,P35269,Q9BUN8,P10586,Q96TA1,Q9Y4G8,Q09161,P35611,P62942,P19474,Q08379,Q92797,P18074,Q06787,Q9H1E3,Q96HY6 18 +Positive regulation of adaptive immune response 0.4554843104347859 0.5682861051395113 0.5698407123518325 1.0 1.0 14 Q9NUQ9,O15400,P04439 3 +Nephron development 0.4546085847624541 0.567734484768092 0.5702152719264009 1.0 1.0 15 P35610,P80723 2 +Trna transcription 0.4854074792391906 0.5668423591458663 0.5708212886017556 1.0 1.0 5 P62875,Q9Y5Q8 2 +Positive regulation of leukocyte mediated immunity 0.4477883091816116 0.563851976514654 0.5728548752040878 1.0 1.0 19 Q9NUQ9,O15400,P04439 3 +Ventricular septum development 0.4526608117233621 0.5635793590384254 0.5730404374892624 1.0 1.0 8 Q13308,Q9ULT8,Q06330,O96028,Q9UMX1,P43243 6 +Spindle elongation 0.4845155140961812 0.5634218616061898 0.5731476541155525 1.0 1.0 5 Q02241 1 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.50030746631262 0.561596794772143 0.5743907647170992 1.0 1.0 4 Q9NWT6 1 +Establishment of endothelial intestinal barrier 0.4508313051909328 0.5615037236450042 0.5744541925842019 1.0 1.0 7 Q9Y4G8,Q9UDY2 2 +Positive regulation of cold induced thermogenesis 0.4542496151402531 0.5604793191701735 0.5751525420162027 1.0 1.0 13 Q16836,Q96E52,P23786,O95140,O15294,P25054,O75175 7 +Mirna catabolic process 0.5705542332540002 0.5578813812675214 0.5769253861957142 1.0 1.0 3 Q8TCS8,O95453 2 +Negative regulation of anion transport 0.7746430999319964 0.5538620634732643 0.5796732496435866 1.0 1.0 2 Q9HD26 1 +Negative regulation of anion transmembrane transport 0.7746430999319964 0.5538620634732643 0.5796732496435866 1.0 1.0 2 Q9HD26 1 +Negative regulation of organic acid transport 0.7746430999319927 0.5538620634732533 0.5796732496435941 1.0 1.0 2 P31751 1 +Stem cell differentiation 0.3589190736192972 0.5535331298680003 0.5798984012659993 1.0 1.0 37 O00330,O94788,Q9NX40,P18074,Q08J23 5 +Regulation of phosphatase activity 0.4504792476802819 0.5529776274686738 0.5802787299397136 1.0 1.0 16 O14920,P62942,O95429,O75116,Q96JB5 5 +Proteasome assembly 0.4485868133303221 0.5519307528900094 0.5809957976072351 1.0 1.0 7 O95456 1 +Inner ear morphogenesis 0.448290933660329 0.550671893167835 0.5818586154848886 1.0 1.0 7 Q13308 1 +Spindle midzone assembly 0.4970476320154188 0.5498289455636451 0.5824367032308608 1.0 1.0 4 Q02241 1 +Amyloid beta formation 0.4514622647200975 0.5495252713444406 0.5826450266271925 1.0 1.0 14 P10909,O75298,Q13526 3 +Amine catabolic process 0.4808227901591039 0.5493237285365455 0.5827833061011081 1.0 1.0 5 P49419 1 +Autophagy of peroxisome 0.5673792228467225 0.5473484048521509 0.5841393947848881 1.0 1.0 3 Q8NEB9 1 +Pattern recognition receptor signaling pathway 0.4086118405849668 0.5463086217353185 0.584853810718772 1.0 1.0 29 O95999,Q07021,Q9NUD5,O43657,Q9Y4E8,Q96RT1,O75179 7 +Apical junction assembly 0.4395892827544914 0.5462467577662827 0.5848963291184937 1.0 1.0 21 P55196,O14920,Q12965,Q13177,P61586,O75116,P25054,O43815,P35221 9 +Positive regulation of gtpase activity 0.3723715106053456 0.5455281237546956 0.585390343331067 1.0 1.0 35 Q13526,Q9H6U6,Q15042,P31751,Q15404,O14641,Q9Y4G8,Q66K14 8 +Regulation of dephosphorylation 0.4084167539091057 0.5451158462874959 0.5856738447690646 1.0 1.0 29 Q13526,P78318,O75116,O14920,P62942,O95429,Q92797,O43768,Q96JB5,Q15435 10 +Negative regulation of protein polymerization 0.4259005794612681 0.5426657148867444 0.587359984168438 1.0 1.0 25 P35241,Q9NUQ9,P04350,Q01082,P16949,Q13813,O15020,P35611,Q14155 9 +Dna dependent dna replication maintenance of fidelity 0.4500703868191412 0.5413213334429148 0.588286118598758 1.0 1.0 13 Q8NFC6,P28340,Q9UNS1,P49959,P51530,Q9H1E3,Q07864 7 +Morphogenesis of a polarized epithelium 0.4494805012411892 0.5403353023273413 0.5889658168119034 1.0 1.0 14 Q13308,O14641 2 +Regulation of notch signaling pathway 0.4456272295989917 0.5393719266901953 0.58963024783023 1.0 1.0 7 Q9NWT6,Q96TA1 2 +Regulation of establishment of planar polarity 0.4456195207431101 0.5393393116803405 0.5896527481385618 1.0 1.0 7 Q13308 1 +Glucan biosynthetic process 0.44968573232133 0.5392375335768318 0.589722964941003 1.0 1.0 12 P11310,P22413,P31751 3 +Positive regulation of nuclease activity 0.5647738864331945 0.5387560553125895 0.590055189444836 1.0 1.0 3 P26583,P23396 2 +Calcium ion regulated exocytosis 0.4449098343247551 0.5363389263433348 0.5917243323785402 1.0 1.0 7 P16615,P35579,Q15042,Q00535 4 +Glial cell proliferation 0.4431843703160967 0.5362738877511033 0.5917692745770453 1.0 1.0 6 P10909 1 +Positive regulation of cell cycle checkpoint 0.4773031843195532 0.5359830887025282 0.5919702382662073 1.0 1.0 5 Q9Y6G9,Q13257 2 +Phosphatidylethanolamine metabolic process 0.7681849082256991 0.534727361394451 0.5928383984177641 1.0 1.0 2 Q8NCC3 1 +Positive regulation of myeloid leukocyte cytokine production involved in immune response 0.4427045177869704 0.5342699086084898 0.5931548081279536 1.0 1.0 6 P14174,Q9NY93,O95999,Q9H2U1 4 +Rna phosphodiester bond hydrolysis 0.3137042460986792 0.5314858280885182 0.595082159413217 1.0 1.0 57 Q8N2A8,Q9UIV1,Q5TA45,Q9BQ61,Q9UQ84,Q6UN15,O15091 7 +Prostanoid metabolic process 0.4476456071676856 0.5311962846734122 0.5952827673093526 1.0 1.0 11 Q8N4Q0,Q8N8N7 2 +Divalent inorganic cation homeostasis 0.3064762220402264 0.5273000893587754 0.5979852122231457 1.0 1.0 52 Q9UJZ1,P20020,Q8TAD4,Q6P4Q7,P62942,Q96AQ8,Q16891,Q9HC07,P05026,Q8NE86,P23634,Q15334 12 +Regulation of mrna catabolic process 0.3291925391265971 0.5270782827948086 0.598139227237809 1.0 1.0 69 Q9Y5S9,A2RRP1,Q99729,Q92804,O75175,P49137,P98175,Q9UIV1,P51114,Q6PJT7,Q06787,P67809,Q9Y2W1,P35637,Q9NPI6,Q9H074,P08670,O75116,P11940,Q14011,Q9P2K5 21 +Axoneme assembly 0.7654656696125106 0.5267477772575452 0.59836875256621 1.0 1.0 2 Q86Y56 1 +Vascular associated smooth muscle cell migration 0.4901317355285427 0.5251334288458598 0.5994904389187616 1.0 1.0 4 P09493 1 +Cellular response to nutrient 0.4402806538399374 0.5241778227987769 0.6001548643143868 1.0 1.0 6 P20020,P09601,Q8TB36 3 +Regulation of ire1 mediated unfolded protein response 0.4401016515190483 0.5234345680122888 0.600671873720136 1.0 1.0 6 Q96HY6 1 +B cell activation 0.3621930309284362 0.5229794247130314 0.6009885715728571 1.0 1.0 36 Q86TM6,P78318,O60934,Q9UQ84,Q96IZ0 5 +Neuron death 0.3313401758577496 0.5227282019425956 0.6011634097191292 1.0 1.0 71 Q99720,Q15392,O95831,P10909,Q9UMX5 5 +Regulation of nuclease activity 0.4412665985699573 0.5210055758049251 0.6023628871446052 1.0 1.0 7 P26583,P12004,O00273,P61221,P06748,P23396 6 +Cellular hormone metabolic process 0.4407907434924405 0.5197807532118542 0.6032163955321745 1.0 1.0 18 O94788 1 +Positive regulation of pattern recognition receptor signaling pathway 0.4444532691976759 0.5196708716185376 0.6032929922745862 1.0 1.0 10 O75179,Q9Y4E8 2 +Regulation of endothelial cell migration 0.4088883322803444 0.5185491012130857 0.6040752110422563 1.0 1.0 28 Q8WTV0,P42785,Q05397 3 +Regulation of microtubule nucleation 0.4404844849209469 0.5177293156867253 0.6046471414161636 1.0 1.0 7 Q14155,Q14203,Q14008,Q9HD47 4 +Negative regulation of establishment of protein localization to mitochondrion 0.4879637400819245 0.5174703974981828 0.6048278283663702 1.0 1.0 4 O95429 1 +Endothelial cell migration 0.3612955034731485 0.5164398092992527 0.6055472677757141 1.0 1.0 36 P42224,P42785,Q9H6U6,Q4VCS5,Q13685,P61586,O75116,Q5JRA6,P09601,P23634,Q8WTV0,Q05397 12 +Negative regulation of lipid biosynthetic process 0.4719292276284517 0.5158032037990451 0.6059918647006315 1.0 1.0 5 Q8NF37,O94905,O60678,P49748 4 +Regulation of hormone metabolic process 0.4719292276284423 0.5158032037990101 0.6059918647006559 1.0 1.0 5 P16435,O75844,O60678,Q9UNE7 4 +Protein o linked glycosylation via threonine 0.5575446846806056 0.5151621480678524 0.6064397171559968 1.0 1.0 3 Q10472 1 +Cellular process involved in reproduction in multicellular organism 0.3127287117272683 0.5147303526467972 0.6067414601781076 1.0 1.0 42 Q8NB78,Q8N2A8,Q96SI9,Q96KQ7,Q12768,Q01085,Q9GZT3,Q08J23 8 +Schwann cell development 0.442258092837906 0.5140147131721889 0.6072417039850295 1.0 1.0 9 P31751 1 +Positive regulation of chemotaxis 0.4408684762875483 0.5129352216246833 0.6079966345366774 1.0 1.0 17 Q8NHP6,Q05397,Q07021,Q8NE86 4 +Positive regulation of map kinase activity 0.4407364622340058 0.5125910518402879 0.6082374138306914 1.0 1.0 8 P14174,P41240,P30040,O14641 4 +Histone lysine demethylation 0.4864923999515761 0.5122917850186365 0.6084468137884067 1.0 1.0 4 Q8NB78 1 +Cytoskeleton dependent intracellular transport 0.3127400193502516 0.5095118006502543 0.6103935288986011 1.0 1.0 58 P46821,Q66K74,Q9BW83,Q92572,O43805,Q9UL25,Q9Y678,O60313,Q96EV8,Q9UBK9,Q03001,A0AVF1,O94901,P33176,Q9UH99,Q12965,Q8TD16,O95817,P23246,P78559,Q00577 21 +Positive regulation of response to biotic stimulus 0.3972174844924744 0.5081127119872427 0.611374300862134 1.0 1.0 30 P23246,Q15233,O14920,Q9NUD5,Q13177,Q9Y4E8,P12956,O75179,Q96PK6,P43243,P61086,Q8WXF1 12 +Muscle organ development 0.3374053063738513 0.5076868719257984 0.6116729565533789 1.0 1.0 39 Q9BYT8,Q8NC56,P09493,P80723,P51114,Q96TA1,P16220,P62942,P61586,P21359,Q9NQ29,Q7Z406,P46939,O94966,P50402 15 +Somatic diversification of immunoglobulins involved in immune response 0.4417219663311729 0.507307817351155 0.611938854361944 1.0 1.0 15 Q9UQ84 1 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.4417219663311729 0.507307817351155 0.611938854361944 1.0 1.0 15 Q9UQ84 1 +Leukocyte cell cell adhesion 0.3527510230608564 0.5070383171136584 0.6121279335017675 1.0 1.0 37 O95999,Q92990,Q9NUQ9,Q5JRA6,Q08722,P61586,Q96IZ0,O43290,P41240,P04439,Q13951,P30825 12 +Regulation of epithelial cell migration 0.3451236437925411 0.5065110402952298 0.6124979412823628 1.0 1.0 38 Q8WTV0,P42785,Q05397 3 +Negative regulation of calcium ion transport 0.4413368053071691 0.5061820012725751 0.6127288890562912 1.0 1.0 10 Q06787,Q9UKS6 2 +Regulation of synaptic vesicle endocytosis 0.5545732743964723 0.5055735402398103 0.6131560604608866 1.0 1.0 3 P0DP25,Q13464 2 +Cellular defense response 0.4830216263799594 0.5001477979525174 0.6169710122286605 1.0 1.0 4 Q9ULC3,O95999 2 +Ubiquitin recycling 0.4824944347472597 0.498312169530395 0.6182640316769197 1.0 1.0 4 Q9Y263,P61086 2 +Response to steroid hormone 0.3232998482169978 0.4964085865859702 0.6196061681557592 1.0 1.0 67 O00330,Q9H7B4,O75874 3 +Negative regulation of neurotransmitter secretion 0.7545887151597309 0.4953047071121005 0.620385048747905 1.0 1.0 2 Q06787 1 +Negative regulation of neurotransmitter transport 0.7545887151597309 0.4953047071121005 0.620385048747905 1.0 1.0 2 Q06787 1 +Regulation of dna helicase activity 0.551058803855844 0.4943174428459087 0.6210820082927333 1.0 1.0 3 Q04837 1 +Negative regulation of epithelial cell differentiation 0.4812921075807198 0.4941347726124184 0.6212110017195327 1.0 1.0 4 P42224 1 +Positive regulation of cell cycle g1 s phase transition 0.4354070149702262 0.4936803009751974 0.621531979474228 1.0 1.0 18 O75179,Q96HY6,Q96DY7,Q6ZWJ1 4 +Regulation of nitric oxide synthase activity 0.4341476834367758 0.4913938546370422 0.6231479098756039 1.0 1.0 7 Q8WTV0 1 +Schwann cell differentiation 0.4376809621631524 0.4904787221001386 0.6237951829740913 1.0 1.0 10 P31751 1 +Alcohol catabolic process 0.4374795480752845 0.4896174383721546 0.6244046342755865 1.0 1.0 10 P30837 1 +Histone h3 k36 methylation 0.7525492861998666 0.4894963231064509 0.6244903570364853 1.0 1.0 2 O60885 1 +Negative regulation of cell projection organization 0.4032050502550468 0.4851587286442787 0.627563755417627 1.0 1.0 28 P08670,O14976,Q9UL15,Q9NQX7,Q9Y4G8,Q8N0X7 6 +Regulation of gluconeogenesis 0.4350050604413475 0.4790698130888774 0.6318889640273739 1.0 1.0 10 Q9BYT8,P11310,Q13043,Q92520,O15294 5 +Regulation of skeletal muscle fiber development 0.7488103331067024 0.478921349505663 0.6319945821487496 1.0 1.0 2 Q96TA1 1 +Positive regulation of nf kappab transcription factor activity 0.4177148884706902 0.4782771734346829 0.6324529408638799 1.0 1.0 24 O14920,P19474 2 +Positive regulation of mrna metabolic process 0.3063894065656267 0.4750102618063393 0.6347796590464831 1.0 1.0 56 O60506,P38159,Q9UIV1,O75116,P62995,Q09161,Q9Y2W1,P11940,Q96E39,P98179,P19338,Q9NPI6,O75175,Q14011,Q9H074,P67809 16 +Microtubule polymerization 0.3864508673437408 0.4744529779333475 0.6351769219703756 1.0 1.0 31 P46821,Q96P70,Q13526,Q9BSJ2,Q16625,P04350,Q9ULW0,Q7Z460,Q9HD47,P16949,P0DMV9,Q14203,Q08379,Q14008,P23396,Q96S59,Q14155 17 +Regulation of peptidyl lysine acetylation 0.4334050230174094 0.4726165075739983 0.6364868031210746 1.0 1.0 16 Q03164 1 +L alpha amino acid transmembrane transport 0.4343999373462978 0.4715970436946302 0.6372144372629733 1.0 1.0 12 O60831,P08195,Q9Y619,O75915,O75746,P30825 6 +Trabecula morphogenesis 0.4746924494946164 0.4714323968979051 0.6373319854244281 1.0 1.0 4 P62942 1 +Circadian rhythm 0.2988664142051965 0.4712956064126011 0.6374296527519361 1.0 1.0 43 Q13547,P23246,P43490,Q9Y2W1,Q03164,Q13330,Q9BWF3,Q9UNS1,Q06210,P16220,P54802,Q8WXF1 12 +Natural killer cell activation 0.4285718532111769 0.4685434683173926 0.639395993474877 1.0 1.0 7 Q96L92,P46379 2 +Regulation of phosphoprotein phosphatase activity 0.4337372081264022 0.4680682565711797 0.6397357787708857 1.0 1.0 13 P62942,O14920,O75116 3 +Cell cycle g1 s phase transition 0.305453946554604 0.4662489925709004 0.6410372846636825 1.0 1.0 56 Q8N6R0,P35241,O75312,Q9UPP1,Q96DY7,P25054,O75179,Q07864,Q96HY6,P23634,P24941,Q6Y7W6,P15927,Q13620,O60885,O00213,O00743,P31350,P42771,P49321,Q6ZWJ1 21 +Carbohydrate homeostasis 0.3609323612879601 0.4650437519764286 0.6419001251324445 1.0 1.0 35 O00330,P42785,P62995,Q9HCD5,Q8NE86,Q9H1E3 6 +Negative regulation of fibroblast proliferation 0.4274227853478716 0.4638737213416295 0.6427382213019368 1.0 1.0 7 Q96IZ0 1 +Neuron apoptotic process 0.2956858017417871 0.4636932878136801 0.64286750685149 1.0 1.0 49 Q99720,O75312,O95831,Q01105,P31751 5 +Endochondral bone morphogenesis 0.472108843537404 0.4626528384392361 0.6436132281667313 1.0 1.0 4 P50454,P16435,P08133 3 +Cartilage development involved in endochondral bone morphogenesis 0.472108843537404 0.4626528384392361 0.6436132281667313 1.0 1.0 4 P50454,P16435,P08133 3 +Glucocorticoid metabolic process 0.4717687074829878 0.4615016311061209 0.6444387514301821 1.0 1.0 4 P51608,Q04917,Q9UNE7 3 +Synaptic vesicle cytoskeletal transport 0.4247784104513094 0.4609225480065111 0.6448541740364719 1.0 1.0 6 Q96EV8,O95295,Q92572 3 +Mitotic spindle midzone assembly 0.5397466511464137 0.4587394932048455 0.6464212499198543 1.0 1.0 3 Q02241 1 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.3333318049727151 0.4578291404510745 0.6470751983716427 1.0 1.0 78 Q96TA1,Q9UQ13,P49137,O14964,P49069,Q9BZF1,P25054,Q9Y4G8,Q9UQB8,Q9H1E3,Q15043,Q12965,P62993,P31751,Q8WWQ0,P22413,P43490,Q6ZWJ1,Q9HCD5,Q96RT1,Q05397 21 +Cellular response to virus 0.413721641767083 0.4570713449179512 0.647619765854528 1.0 1.0 24 O75179,Q9Y4E8,Q06787,O43657 4 +Response to peptide hormone 0.3356655664289064 0.4559777969918728 0.648405944407509 1.0 1.0 80 Q16836,Q08170,Q9BZF1,P25054,Q9UQB8,Q9H1E3,Q13243,Q15043,P61026,O75150,Q12965,O60763,P62993,P16220,P31751,P42224,Q8WWQ0,P20020,P22413,P43490,Q6ZWJ1,Q9Y266,Q13247,P41240,Q9HCD5,Q05397 26 +Microtubule polymerization or depolymerization 0.3059972607235068 0.4553807799907032 0.6488353201616164 1.0 1.0 42 P46821,Q66K74,Q13526,Q9BSJ2,P04350,Q7Z460,P16949,Q14203,Q08379,O15344,P25054,P78559,Q14155 13 +Establishment or maintenance of cytoskeleton polarity 0.4699321730668686 0.4553046578255925 0.6488900757610783 1.0 1.0 4 P02545,Q14008 2 +Replication fork processing 0.426912301971684 0.4551490441225344 0.6490020164958505 1.0 1.0 8 Q9H1E3 1 +Regulation of cytoplasmic translation 0.4306538749510569 0.4549972493943721 0.6491112176898883 1.0 1.0 14 P11940,Q06787,Q9H074,P67809 4 +Import across plasma membrane 0.4302326523766347 0.4548807508249776 0.6491950319275079 1.0 1.0 15 P31751,P05026,P08195,P30825,Q15043,P23634 6 +Stress granule assembly 0.4302053699783298 0.4547580415442858 0.6492833192294498 1.0 1.0 15 Q14157,Q9UN86,Q8WWM7,P31483,Q14011 5 +Blood vessel endothelial cell migration 0.4190182384486671 0.454156940776241 0.649715872469661 1.0 1.0 22 P42785,Q4VCS5,P61586,Q5JRA6,P09601,P23634,Q8WTV0 7 +Neutrophil migration 0.4299524577014473 0.4518925095457997 0.6513464208563038 1.0 1.0 14 O00429,Q07021,Q8NHP6,Q8NE86,P35613,Q00013 6 +Regulation of establishment of protein localization to mitochondrion 0.4243474365468049 0.4484282762164874 0.6538441385834217 1.0 1.0 19 P55786 1 +Positive regulation of translation 0.3021294250217218 0.4477997687224137 0.6542977103453986 1.0 1.0 55 Q07021,P08670,P51114,Q14011,P98179,Q71RC2,Q06787,Q9H074,P67809 9 +Lipid droplet formation 0.5360701678506016 0.4474003683466507 0.6545860099096392 1.0 1.0 3 Q14534 1 +Response to bacterium 0.3060523132492523 0.4468621800340424 0.6549745723862648 1.0 1.0 58 Q86U42,Q9NZ08,P08670,P01889,Q9NUQ9,Q96RT1,O75179,P04439,Q9UQB8,Q9Y263,Q8WTV0 11 +Positive regulation of immune effector process 0.3870614916866086 0.4462356454086034 0.6554270370683268 1.0 1.0 30 P01889,Q9NUQ9,O75179,P04439,O15400 5 +Mrna cis splicing via spliceosome 0.4281114652423941 0.4453667011889892 0.6560547721375274 1.0 1.0 15 P54105,Q12872,Q96I25,Q09161,Q9Y2W2,Q07955,O75400,Q15459 8 +Positive regulation of innate immune response 0.4114593802973659 0.4451579870263953 0.6562055857984519 1.0 1.0 24 P23246,Q15233,O14920,Q9NUD5,Q13177,P12956,Q96PK6,P43243,P61086,Q8WXF1 10 +Atp biosynthetic process 0.4196771641436758 0.4451463759656539 0.6562139761848247 1.0 1.0 21 P00846 1 +Dna replication independent chromatin organization 0.4524292881000226 0.4446815761532297 0.6565498854969234 1.0 1.0 5 P49321,O14929,Q9Y5B9 3 +Keratinocyte proliferation 0.4203241614332643 0.4431937924658579 0.6576255684811247 1.0 1.0 6 Q13247,Q6ZWJ1 2 +Regulation of keratinocyte proliferation 0.4203241614332643 0.4431937924658579 0.6576255684811247 1.0 1.0 6 Q13247,Q6ZWJ1 2 +Positive regulation of protein kinase activity 0.2973501699492554 0.441036226054493 0.659186771321584 1.0 1.0 52 Q13432,Q15334,Q99627,Q9BZF1,Q13177,Q13043,P61586,P12956,P41240,O14641,P10909,Q9Y4G8,Q05397,P23634,Q96M27 15 +Negative regulation of erk1 and erk2 cascade 0.426774931944216 0.438778708822144 0.6608218890809008 1.0 1.0 12 Q99956 1 +Golgi to endosome transport 0.4189925119128706 0.4379350954286897 0.6614333338077596 1.0 1.0 6 O95782,Q99523,P61106,Q92538,Q96RL7 5 +Positive regulation by host of viral transcription 0.4501672966439257 0.4366628549606499 0.662355871440325 1.0 1.0 5 Q9H1E3,Q13573 2 +Positive regulation of lipase activity 0.4182520920202169 0.435019613970902 0.6635481905834675 1.0 1.0 6 Q9Y263 1 +Neuron projection maintenance 0.7324949014276032 0.4339370884957687 0.6643341262045932 1.0 1.0 2 P78559 1 +Regulation of cell cycle g1 s phase transition 0.3496904746505 0.433338654982472 0.6647687597115659 1.0 1.0 36 P24941,Q8N6R0,Q6Y7W6,Q96DY7,P35241,P15927,P31350,Q6ZWJ1,Q13620,P25054,O00213,Q96HY6,P23634,O75179 14 +Negative regulation of phagocytosis 0.419519940881165 0.4321389459861161 0.6656404301956111 1.0 1.0 7 Q08722,O60493,Q9NT62 3 +Positive regulation of torc1 signaling 0.4629251700680129 0.43196054174843 0.6657700916853679 1.0 1.0 4 Q9NWS0,Q96EE3,Q9Y4R8 3 +Negative regulation of dna binding transcription factor activity 0.4087675947050911 0.4310807962818602 0.6664096233921155 1.0 1.0 24 Q9UN86,P19474,Q96RT1,Q96JB5,P09525,Q00577 6 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.3197867279133688 0.4308462516037538 0.6665801668178557 1.0 1.0 40 P10909,O75150,Q9Y5A7,Q96JB5,Q06787,Q96HY6,Q05397 7 +Regulation of microtubule depolymerization 0.4248907480717719 0.4307724633835618 0.6666338236816165 1.0 1.0 12 Q66K74,Q7Z460,O15344,P25054,P78559 5 +Endoplasmic reticulum organization 0.3115373355404971 0.4300604316874032 0.6671516821088925 1.0 1.0 41 Q9NPA0,P49069,P61026,Q9H2M9,O14976,Q9C0E8,Q9NP72,Q8NFQ8,Q15042,Q00765,Q8NHH9,Q5JRA6,O15027,O00429,P46379 15 +Regulation of histone ubiquitination 0.4230704969108367 0.4291212505871921 0.6678349881190828 1.0 1.0 10 Q5VTR2,Q9NW82 2 +Positive regulation of myelination 0.7301155676410364 0.4275408377133092 0.6689854470650052 1.0 1.0 2 Q9UPY3 1 +Chromosome attachment to the nuclear envelope 0.729775662814415 0.4266306014001764 0.6696484051472136 1.0 1.0 2 O94901 1 +Regulation of cardiac muscle adaptation 0.7297756628144151 0.4266306014001755 0.6696484051472142 1.0 1.0 2 P23634 1 +Negative regulation of muscle adaptation 0.7297756628144151 0.4266306014001755 0.6696484051472142 1.0 1.0 2 P23634 1 +Negative regulation of cardiac muscle adaptation 0.7297756628144151 0.4266306014001755 0.6696484051472142 1.0 1.0 2 P23634 1 +Protein peptidyl prolyl isomerization 0.410809647230429 0.4262709620729178 0.6699104144916315 1.0 1.0 23 Q96BP3,Q96AY3,Q9Y680,P62942,Q9NWM8 5 +Oxidative phosphorylation 0.3072760691266982 0.4214176951307636 0.6734501000904178 1.0 1.0 61 P00403,P03886,O96000,P00846 4 +Positive regulation of transcription regulatory region dna binding 0.413935033176144 0.418143381829891 0.6758422884941646 1.0 1.0 6 Q96TA1 1 +Cholesterol efflux 0.4159359590527263 0.4179761793631572 0.6759645334797799 1.0 1.0 7 Q8WTV0 1 +Regulation of protein secretion 0.3015767289556668 0.4171399384721791 0.676576053672191 1.0 1.0 42 O00330,Q9NV70,Q16836,O95486,Q8NEB9,Q6ZWJ1,Q16850,Q9Y5K6,Q8NE86,O43768,O00213,Q32P28,O00429,Q15334 14 +Regulation of neuron differentiation 0.4191288651211329 0.4168562521485687 0.6767835542392056 1.0 1.0 18 Q96JB5,Q8WUJ1,O60271 3 +Regulation of sister chromatid cohesion 0.4169675517851601 0.4150840316174854 0.6780803886902858 1.0 1.0 8 P23246,Q96MF7,Q7Z5K2 3 +Negative regulation of cell size 0.4576609947364752 0.414746061204426 0.6783278092975631 1.0 1.0 4 P61586,P35241 2 +Sterol biosynthetic process 0.4081762606526816 0.4129157019522569 0.6796683764769942 1.0 1.0 23 Q15392,Q15800,Q16850,Q14534,P48449 5 +Apoptotic process involved in development 0.4432858285384139 0.4125886619669073 0.679908009553263 1.0 1.0 5 O75312 1 +Positive regulation of dna templated transcription elongation 0.420489394172595 0.4122376625116608 0.6801652345064737 1.0 1.0 12 P35269,Q96FV9,Q9Y5B9,O00267,O60885,O95251 6 +Oocyte differentiation 0.4177011347589122 0.4120758261217253 0.6802838465396677 1.0 1.0 9 Q8N2A8 1 +Positive regulation of glial cell differentiation 0.4120912895547357 0.4110010291744428 0.6810717800473081 1.0 1.0 6 Q9UPY3 1 +Regulation of release of cytochrome c from mitochondria 0.4204722192661413 0.4107345390066307 0.6812671978464104 1.0 1.0 13 P10909 1 +Viral budding 0.4194162988835212 0.4103996187169412 0.6815128259314824 1.0 1.0 11 Q9NP79,Q8WUX9,Q9NZZ3,Q9Y3E7,Q9UN37,O75351 6 +Regulation of short term neuronal synaptic plasticity 0.7236573759347187 0.4103986620213184 0.6815135276134106 1.0 1.0 2 Q15042 1 +Sensory perception of pain 0.5236314178850858 0.4099017834025279 0.6818779970889937 1.0 1.0 3 P27361,Q00535 2 +Keratinization 0.7229775662814446 0.4086131249716648 0.6828235971753513 1.0 1.0 2 Q8NEY8 1 +Protein targeting to vacuole 0.419727157859706 0.4083070174886276 0.6830482879498194 1.0 1.0 15 P10909,Q5THJ4 2 +Cell migration involved in sprouting angiogenesis 0.4111675564634839 0.4074376417332513 0.6836865852317899 1.0 1.0 6 P61586,P09601,Q5JRA6 3 +Cytoplasmic microtubule organization 0.4197563324146087 0.4074352760678143 0.6836883224164032 1.0 1.0 14 Q9BSJ2,Q03001,Q7Z460,P61586,Q14203 5 +Immune response regulating cell surface receptor signaling pathway 0.39368888684402 0.407247007038273 0.6838265798200316 1.0 1.0 27 O95999,O14920,Q08722,Q96IZ0,P04439,Q05397,P46379 7 +Morphogenesis of an epithelial sheet 0.4131672156093342 0.4071374115949674 0.6839070673042866 1.0 1.0 7 Q7Z460,O14641 2 +Positive regulation of lipid transport 0.4547619047618897 0.4053885602170075 0.685191918551961 1.0 1.0 4 P14174,P33121,P07355 3 +Positive regulation of ubiquitin protein transferase activity 0.4180374482266605 0.4047314634377597 0.6856749120240189 1.0 1.0 11 Q9BTE7,Q92564,Q13526 3 +Regulation of deoxyribonuclease activity 0.4409663150731562 0.4045861669114923 0.6857817283661733 1.0 1.0 5 P06748,P23396,P12004,O00273 4 +Regulation of protein acetylation 0.416356109302389 0.4041147115714174 0.6861283671883216 1.0 1.0 18 Q03164 1 +Calcium ion transmembrane transport 0.3000162791860954 0.4037928140032231 0.6863650811989443 1.0 1.0 42 P20020,P62942,Q96AQ8,Q9HC07,P05026,Q8NE86,Q06787,P23634 8 +Interleukin 6 mediated signaling pathway 0.5209112546752891 0.4018866831460699 0.6877674236914126 1.0 1.0 3 P40763,Q13546 2 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.4399045266521523 0.4009422921968066 0.6884626115035204 1.0 1.0 5 Q9Y6G9,Q13257 2 +Protein stabilization 0.3200574048304876 0.3956512723905998 0.6923623071465737 1.0 1.0 73 Q9UL25,P78371,P49069,P40855,P05026,P10909,O15027,P46379,Q86TM6,Q13526,O95817,Q9UL15,O94966,O60716,Q32P28,O95785,Q6ZWJ1,Q9H2J4,O95429 19 +Peroxisome fission 0.518721769304564 0.3954852835048565 0.6924847803609457 1.0 1.0 3 O00429 1 +Nucleoside triphosphate metabolic process 0.28286774523955 0.3953175777024819 0.692608528550152 1.0 1.0 45 P22413,Q9UJZ1,P00846,Q9H773,P55263,Q9ULC3,Q9UIJ7,P00403,P61586,P17812,P06576 11 +Positive regulation of neurotransmitter uptake 0.7175390890550679 0.3944609277486154 0.6932407686586546 1.0 1.0 2 P20337 1 +Cellular response to low density lipoprotein particle stimulus 0.7175390890550679 0.3944609277486154 0.6932407686586546 1.0 1.0 2 O15118 1 +Nucleosome organization 0.2895034321414086 0.3936665700268991 0.6938272256867148 1.0 1.0 50 P49321,Q9NRG0,Q9H7B4,P55209,Q9NRF9,Q01105,Q99733,P17096 8 +Response to epidermal growth factor 0.4162934581426414 0.3933937752455222 0.6940286664666895 1.0 1.0 15 O75312,P12270,O95429,Q9UQB8 4 +Nadp metabolic process 0.4157292912382165 0.3929792694341069 0.6943347927830712 1.0 1.0 16 P48735 1 +Response to peptide 0.3410692754662758 0.392840929891538 0.6944369722339743 1.0 1.0 90 Q16836,O95251,Q08170,Q9BZF1,P25054,Q9UQB8,Q9H1E3,Q13243,Q15043,P61026,O75150,Q9NZZ3,Q12965,O60343,O15294,Q9UNS1,O60763,P62993,P16220,Q96RT1,P31751,P42224,Q8WWQ0,P20020,P22413,P43490,P08670,Q6ZWJ1,Q9Y266,Q13247,P41240,Q9HCD5,O75116,Q05397 34 +Mononuclear cell migration 0.4086943643004943 0.3916187456288813 0.695339935062379 1.0 1.0 21 Q8NHP6,Q08722,Q5JRA6,Q05397 4 +Positive regulation of defense response to virus by host 0.4370439205400533 0.3911867174341479 0.6956592255932388 1.0 1.0 5 P42224,O60828,Q8TDB6 3 +Positive regulation of isotype switching to iga isotypes 0.7158395649218253 0.3900870838973261 0.6964721533662495 1.0 1.0 2 O96028 1 +Granulocyte migration 0.4131148639206274 0.3893581090197748 0.6970112560428432 1.0 1.0 18 Q8NHP6,Q05397,Q8NE86 3 +Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway 0.5160292226682855 0.3876751878968536 0.6982564197354177 1.0 1.0 3 O75351 1 +Cell junction maintenance 0.4059780267157052 0.3876092338322059 0.6983052345534468 1.0 1.0 6 Q15334 1 +Regulation of actin filament length 0.3142985390964931 0.3873063072094829 0.6985294567455136 1.0 1.0 40 Q9UQB8,P35241,Q14019,Q9NUQ9,Q01082,Q14247,P61586,O95429,O15020,P62993,P35611 11 +Skeletal muscle organ development 0.3963509337201852 0.3831903563750057 0.7015786278375871 1.0 1.0 25 Q9BYT8,Q8NC56,P80723,P51114,Q96TA1,P61586,P21359,Q7Z406,O94966,P50402 10 +Pigment granule organization 0.4045072299363366 0.3820497687998838 0.7024244493594787 1.0 1.0 6 Q96EV8,O95295,Q9BXS5 3 +Vitamin transmembrane transport 0.4472371606244464 0.3815229948722904 0.7028152117558688 1.0 1.0 4 Q8WTV0 1 +Regulation of rac protein signal transduction 0.4469703331972361 0.3806881881001905 0.7034346346161628 1.0 1.0 4 P21359 1 +Extracellular matrix assembly 0.4333876760988027 0.3788509599373015 0.7047985425567689 1.0 1.0 5 Q96AY3 1 +Endothelial cell development 0.4103715625413692 0.3769881735652934 0.7061823937612339 1.0 1.0 18 P35241,Q9UDY2,O14920,Q9Y4G8,O75116,P35611 6 +Positive chemotaxis 0.4328002722014351 0.3768833080115439 0.706260326603547 1.0 1.0 5 P26583,P14174,Q14160,P09429 4 +Regulation of leukocyte mediated immunity 0.3981648129250619 0.3767376073519078 0.7063686119485844 1.0 1.0 24 Q9NUQ9,O15400,P04439 3 +Protein k29 linked ubiquitination 0.7104010876954487 0.37624951360026 0.7067314085823562 1.0 1.0 2 Q15386 1 +Free ubiquitin chain polymerization 0.7104010876954489 0.3762495136002594 0.7067314085823566 1.0 1.0 2 P61086 1 +Histone monoubiquitination 0.4091265924823101 0.3728959421145884 0.709225892280902 1.0 1.0 10 O75150,Q5VTR2,Q96T88 3 +Microvillus assembly 0.4314472930812785 0.3723663187795915 0.709620127495606 1.0 1.0 5 Q9Y4G8 1 +Camera type eye morphogenesis 0.4017448243542678 0.3716820486564044 0.7101295921058703 1.0 1.0 6 P21359,P54802 2 +Amyloid beta metabolic process 0.4105030119129018 0.3702330931312534 0.7112088209809992 1.0 1.0 16 P10909,O75298,Q13526 3 +Tight junction organization 0.4092670056122355 0.3677678410883883 0.7130463501148538 1.0 1.0 17 P55196,O14920,Q12965,Q13177,O75116,P25054,O43815 7 +Organic hydroxy compound catabolic process 0.4096661543037206 0.3677141606743484 0.7130863805535101 1.0 1.0 12 P30837 1 +Regulation of animal organ morphogenesis 0.4059605142991805 0.3658123655748164 0.7145050921037166 1.0 1.0 9 Q13308 1 +Negative regulation of lymphocyte activation 0.4091847055082757 0.3637051074984052 0.7160782289724688 1.0 1.0 13 Q96IZ0,Q92990 2 +Regulation of heart growth 0.4063208666265597 0.3618866767054959 0.7174367165770885 1.0 1.0 10 Q99956 1 +Endoplasmic reticulum mannose trimming 0.4404971509673007 0.3606841328517318 0.718335587542795 1.0 1.0 4 Q86TM6 1 +Cellular monovalent inorganic cation homeostasis 0.3850009715440133 0.3603037906887926 0.718619964869144 1.0 1.0 27 Q9HC07,P05026 2 +Regulation of phagocytosis 0.4081018693873416 0.3592857186949903 0.7193813569114109 1.0 1.0 13 Q9NT62,Q08722,P41240,O60493,Q8WTV0 5 +Protein depolymerization 0.2947202744882414 0.3591318439440022 0.7194964604591594 1.0 1.0 42 P46821,Q66K74,P35241,Q01082,O14976,Q7Z460,P35611,P16949,Q12797,Q13813,P78559,O15344,O15020,P25054,O75351,P52907 16 +Rna guanine n7 methylation 0.7032630863358296 0.3584620596257088 0.7199975559845386 1.0 1.0 2 O43148 1 +Muscle structure development 0.3417316332160757 0.3561275304416448 0.7217450607122518 1.0 1.0 94 Q9NWT6,Q13547,O60271,Q9H7B4,Q92990,P09493,P80723,P51114,Q96TA1,P11310,P62942,Q9BWF3,Q9NQ29,O75179,Q7Z406,O94966,Q9P2K5,P67809 18 +Dna replication dependent chromatin organization 0.3975493533015473 0.356124776720074 0.7217471228620376 1.0 1.0 6 P49321,O14929,Q8TEX9,Q13111,Q13112 5 +Mrna cleavage 0.4047419419115352 0.3557385233998339 0.7220363922512194 1.0 1.0 10 Q09161,Q6UN15 2 +Positive regulation of posttranscriptional gene silencing 0.4074821033537086 0.3557305124309967 0.7220423921753902 1.0 1.0 14 Q06787,Q01085 2 +Regulation of postsynaptic membrane potential 0.403623735379747 0.3514053002241192 0.7252843066336543 1.0 1.0 10 Q9UQB8,Q15042 2 +Chemical synaptic transmission postsynaptic 0.403623735379747 0.3514053002241192 0.7252843066336543 1.0 1.0 10 Q9UQB8,Q15042 2 +Positive regulation of tumor necrosis factor mediated signaling pathway 0.4374149659863835 0.3513302967126855 0.7253405683277103 1.0 1.0 4 P0DMV9,P61086,Q13546 3 +Negative regulation of telomere maintenance 0.4020371200746876 0.3507562363982774 0.7257712319884677 1.0 1.0 9 O60934 1 +Regulation of defense response to virus 0.4059945297851394 0.3507334142057601 0.7257883551341966 1.0 1.0 13 O43657,Q07021 2 +Monovalent inorganic cation homeostasis 0.3793290744700942 0.3506432545834935 0.7258560018748057 1.0 1.0 28 Q9HC07,P05026 2 +Regulation of protein polymerization 0.2993549515361989 0.3502328126562983 0.7261639833648517 1.0 1.0 61 P46821,P35241,Q01082,Q14203,Q14155,Q14019,Q7Z460,P35611,Q9UQB8,P52907,Q14247,P16949,P61586,O15020,P62993,Q9NUQ9,P04350,O95429,Q13813 19 +Tissue migration 0.285965283015502 0.3495105886068311 0.7267060228954192 1.0 1.0 51 P42224,P42785,Q9H6U6,Q4VCS5,Q13685,Q7Z460,P61586,O75116,Q5JRA6,P09601,P23634,Q8WTV0,Q05397 13 +Negative regulation of dna metabolic process 0.3374870698273129 0.3493236114874724 0.7268463742205209 1.0 1.0 36 O60934,P53999,Q96TA1,Q03164 4 +Toll like receptor 3 signaling pathway 0.4353741496598566 0.3451989788753106 0.7299447863764874 1.0 1.0 4 Q9UMX0,O75955,Q14254 3 +Cell death in response to oxidative stress 0.3944165342600586 0.3449532991506439 0.7301294800492373 1.0 1.0 23 Q99720 1 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.2798934511057381 0.3435798546344752 0.7311622770637591 1.0 1.0 47 Q13526,P08670,Q01082,Q9Y2U8,Q9UIQ6,Q9Y4E8,P62942,P53999,Q96PK6,Q8N0X7,Q05397 11 +Establishment of tissue polarity 0.4015142935567528 0.343278826199636 0.7313887083475987 1.0 1.0 10 Q13308 1 +Platelet derived growth factor receptor signaling pathway 0.3982969910376779 0.3431247352814284 0.7315046234122358 1.0 1.0 8 Q12965 1 +Mitochondrion morphogenesis 0.3999105603811399 0.3426845020482872 0.7318358231110957 1.0 1.0 9 Q7Z406,Q9GZT3 2 +Regulation of insulin secretion 0.4011390048872703 0.3411747974128832 0.7329719950310198 1.0 1.0 19 O00330,Q16836,Q8NE86,O43768 4 +Microtubule bundle formation 0.4029898383584379 0.3410511025063596 0.7330651111892474 1.0 1.0 12 P46821,Q66K74,Q86Y56,O43663,O95235,Q7Z460,A0AVF1 7 +Regulation of myeloid leukocyte mediated immunity 0.3928250381649235 0.3388882480236424 0.7346939178780572 1.0 1.0 6 Q92499,Q9NY93,P09601,Q9H2U1 4 +Mitochondrial respiratory chain complex assembly 0.3077771624590479 0.3368152618257493 0.7362561673627592 1.0 1.0 40 O95831,O96000,P03886 3 +Long term synaptic potentiation 0.3964737978157617 0.3363473173617416 0.7366089721097526 1.0 1.0 8 Q9BPZ3,P21359,Q92542 3 +Response to acid chemical 0.3870053106179604 0.3356819945138891 0.7371106850454208 1.0 1.0 25 O00330,O95831 2 +Regulation of intracellular protein transport 0.3092041182064691 0.3339973447378295 0.7383815623263077 1.0 1.0 70 P27105,Q9H300,Q9H6U6,O75312,P55786,Q9C0E2,Q05D32,Q9ULC3,Q12965,Q9Y282,O95429,P12270,P50402,P31751 14 +Response to fungus 0.393583489835417 0.3332318289738132 0.7389592937451284 1.0 1.0 7 Q9Y4E8,Q14019 2 +Defense response to fungus 0.393583489835417 0.3332318289738132 0.7389592937451284 1.0 1.0 7 Q9Y4E8,Q14019 2 +Ire1 mediated unfolded protein response 0.3934818933827211 0.332861858974411 0.7392385613450927 1.0 1.0 7 Q96HY6 1 +Protein targeting to lysosome 0.3999728290736747 0.33280213721509 0.7392836448533686 1.0 1.0 11 P10909 1 +Regulation of smooth muscle contraction 0.4311220768528484 0.3325863457018739 0.7394465517158129 1.0 1.0 4 P20020,Q14247 2 +Defense response to symbiont 0.2880694141056665 0.3325091411680939 0.7395048383512521 1.0 1.0 54 Q9UIV1,Q07021,O43657,Q9Y4E8,P19474,O75179,Q9NV70 7 +Positive regulation of double strand break repair 0.3999439440134468 0.3310268307394345 0.7406242189982521 1.0 1.0 18 Q9UBU8,Q9UNS1,P35637 3 +Negative regulation of lymphocyte apoptotic process 0.4184860677704238 0.3302032994644538 0.7412463539220873 1.0 1.0 5 Q99576 1 +Negative regulation of leukocyte apoptotic process 0.4184860677704238 0.3302032994644538 0.7412463539220873 1.0 1.0 5 Q99576 1 +Positive regulation of secretion 0.2783553304855927 0.3298846664954596 0.7414871099289986 1.0 1.0 47 O14964,Q96EV8,O00330,Q9NV70,O95486,Q92783,Q7Z460,Q9Y5K6,Q15042,Q8NE86,P16220,O00429 12 +Response to interleukin 6 0.4174889418169568 0.3270457632553035 0.7436332726007184 1.0 1.0 5 Q96JM3,Q6PD62,P40763,Q13546 4 +L aspartate transmembrane transport 0.4285714285714327 0.325127414731156 0.7450846411679906 1.0 1.0 4 O75746,Q15758,Q9H936 3 +Positive regulation of protein catabolic process 0.3002493055929285 0.3236838220439555 0.7461774201703806 1.0 1.0 64 P35241,Q96JB5,Q06787,O75150,Q9H270,O43847,Q9UKS6,Q9Y5A7,P25054,P10909,Q05397,Q96HY6,P46379 13 +Regulation of nmda receptor activity 0.6883072739632738 0.3226210042502151 0.7469822845737499 1.0 1.0 2 Q15334 1 +Regulation of neurotransmitter receptor activity 0.6883072739632738 0.3226210042502151 0.7469822845737499 1.0 1.0 2 Q15334 1 +Regulation of protein stability 0.3507492483167778 0.3211992857926481 0.7480593733483512 1.0 1.0 105 Q9BUN8,P48449,Q9UL25,P19474,P12270,P78371,P49069,Q9H270,P40855,P05026,P10909,O15027,Q96HY6,P46379,Q86TM6,Q13526,O95817,Q9UL15,O94966,Q32P28,O60716,Q68CQ4,O95785,Q6ZWJ1,Q9H2J4,O95429 26 +Regulation of nervous system process 0.3955882747631136 0.3207932470970874 0.7483670772012878 1.0 1.0 10 Q06787,Q9UQB8,Q9UPY3 3 +Early endosome to golgi transport 0.3901071795246247 0.3206564752955402 0.748470734503105 1.0 1.0 7 O15260,O60499 2 +Centriole elongation 0.6872875594833489 0.3202496744339668 0.7487790696518577 1.0 1.0 2 O75351 1 +Response to vitamin d 0.4149055265466203 0.3189243640985911 0.7497838684268698 1.0 1.0 5 P20020,Q8TB36 2 +Somatic diversification of immunoglobulins 0.3970143444555587 0.3184318459265768 0.750157384907479 1.0 1.0 18 Q9UQ84 1 +Regulation of peptide transport 0.3927964266491269 0.317503914321732 0.7508612698135542 1.0 1.0 21 O00330,Q16836,Q8NE86,O43768 4 +Embryonic axis specification 0.3868352425443618 0.3174811827929593 0.7508785154781079 1.0 1.0 6 P80723 1 +Embryonic pattern specification 0.3868352425443618 0.3174811827929593 0.7508785154781079 1.0 1.0 6 P80723 1 +Anterior posterior axis specification 0.3868352425443618 0.3174811827929593 0.7508785154781079 1.0 1.0 6 P80723 1 +Regulation of muscle cell differentiation 0.392290595205617 0.3152176941430013 0.7525963718963788 1.0 1.0 21 O75179,Q96TA1,Q9BWF3,P67809 4 +Regulation of protein autophosphorylation 0.3940882361122071 0.3151841141193918 0.752621866433459 1.0 1.0 10 O60934,P22413 2 +Deoxyribonucleoside triphosphate metabolic process 0.3859072234053369 0.3142105415219574 0.753361136870041 1.0 1.0 6 Q9H773 1 +Regulation of voltage gated calcium channel activity 0.4130809448540579 0.3132406696731871 0.7540978220836083 1.0 1.0 5 Q06787 1 +Negative regulation of cell matrix adhesion 0.3877605439155527 0.3122667705340539 0.75483779154134 1.0 1.0 7 P21359,Q9H6U6 2 +Protein localization to microtubule 0.3876284494881836 0.3117969168155242 0.7551948673514224 1.0 1.0 7 Q96JM3,P78559 2 +Positive regulation of protein autophosphorylation 0.3874607930391731 0.3112009431487609 0.7556478660828543 1.0 1.0 7 O60934 1 +Positive regulation of dendrite morphogenesis 0.3928389189791647 0.3105385687534668 0.7561514344950138 1.0 1.0 10 Q9UL25,Q9UQB8 2 +Synaptic vesicle recycling 0.396421975448411 0.3104363276472371 0.7562291722642416 1.0 1.0 15 O14976 1 +Regulation of adaptive immune response 0.3940542621940266 0.3101227224484101 0.7564676335129819 1.0 1.0 19 Q9NUQ9,O15400,P04439 3 +Rhythmic behavior 0.4232611192712892 0.3098612775729578 0.7566664504694518 1.0 1.0 4 P54802 1 +Cellular response to lipid 0.3374597308170137 0.3094552974443508 0.756975211843943 1.0 1.0 95 Q9H7B4,Q96JM3,O94788,Q13573,Q13308,Q9H270,O95831,O15118,P10909,Q96HY6,Q8WTV0,Q8TB36,Q9NS86,Q9P0J0,P61586,P16220,Q9GZZ9,Q86U42,Q13547,P20020,O95999,P08670,Q86UE4,O75116,Q9Y263,P61960 26 +Response to interferon gamma 0.3844423528865991 0.3093165394365711 0.7570807508159965 1.0 1.0 24 P08670,Q12965,Q08722,P19474,Q9Y5A7 5 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.41176930161612 0.3091818202982376 0.7571832221686841 1.0 1.0 5 Q9NP79,Q8WUX9,Q92783 3 +Sulfur amino acid biosynthetic process 0.411419748600063 0.3081039760979791 0.7580032158205638 1.0 1.0 5 Q13126 1 +Methionine biosynthetic process 0.411419748600063 0.3081039760979791 0.7580032158205638 1.0 1.0 5 Q13126 1 +Methionine metabolic process 0.411419748600063 0.3081039760979791 0.7580032158205638 1.0 1.0 5 Q13126 1 +Positive regulation of protein localization to cell surface 0.4221088435374007 0.3065963661919831 0.7591506198796771 1.0 1.0 4 P78559,Q92544,Q9HD47 3 +Regulation of chromatin assembly or disassembly 0.3948043918503721 0.3064377084313511 0.7592714012111585 1.0 1.0 13 P24941,Q9UPP1,Q66K74,Q8NEY8 4 +Positive regulation of extrinsic apoptotic signaling pathway 0.3952171931226151 0.3062752915401611 0.7593950503371985 1.0 1.0 14 O95999,Q13177,Q13043,P21359,P30154,Q9NQX7 6 +Regulation of dna binding transcription factor activity 0.2916728420932221 0.3061429241287239 0.7594958271314987 1.0 1.0 59 P22413,O95999,Q96RT1,O14920,Q9UN86,Q86UE4,P19474,O14641,Q96JB5,P10909,P09525,Q96HY6,Q00577 13 +Renal tubule development 0.3832331800966615 0.3048570689929221 0.7604750142066492 1.0 1.0 6 P35610 1 +Establishment of mitotic spindle localization 0.3931670388762981 0.3030266261006775 0.7618695703007148 1.0 1.0 12 P05556,Q9UNZ2,Q7Z460,Q14203,Q13257 5 +Negative regulation of protein binding 0.3854610760949354 0.3025233573098638 0.7622531305425226 1.0 1.0 23 Q96EV8,P35269,Q13526,P10586,Q08379 5 +Positive regulation of cell cycle phase transition 0.2877715646206615 0.3021673597737862 0.7625244850452957 1.0 1.0 42 Q96MF7,P35241,O43660,O75351,Q96DY7,Q9UJX3,Q9UJX5,P06748,O75179,Q96HY6,Q15398,Q13042,Q96FV9,Q13620,O60885,P31350,Q6ZWJ1,Q13618,P54652 19 +Regulation of synaptic vesicle exocytosis 0.3935385858979991 0.301550477183996 0.762994764895434 1.0 1.0 13 Q06787,Q15042,Q4J6C6 3 +Maintenance of dna repeat elements 0.4200680272108891 0.300856147797774 0.7635241908839985 1.0 1.0 4 O75844,P43246,P52701 3 +Lipoprotein localization 0.381785287905718 0.2998368846533218 0.7643015790772998 1.0 1.0 6 Q5JRA6,O15260 2 +Nucleotide excision repair dna gap filling 0.6777702243371899 0.2985755088673102 0.7652639545808442 1.0 1.0 2 Q07864 1 +Purine ribonucleoside metabolic process 0.3855447316391166 0.2967339959167769 0.7666696003680995 1.0 1.0 8 O60725 1 +Ribonucleoside metabolic process 0.3855447316391166 0.2967339959167769 0.7666696003680995 1.0 1.0 8 O60725 1 +Protein monoubiquitination 0.3878553632631457 0.2953749014286991 0.7677075041857742 1.0 1.0 21 Q5VTR2,P19474 2 +Positive regulation of helicase activity 0.4069411364409649 0.2944389446845626 0.7684225115407182 1.0 1.0 5 P52701,P20585,P43246,Q04837 4 +Regulation of gene silencing by rna 0.3919374463476883 0.2942512899249414 0.7685658907611868 1.0 1.0 17 Q06787,Q01085 2 +Protein targeting to mitochondrion 0.279597955372872 0.2936007367991622 0.7690630126993112 1.0 1.0 51 Q5JRX3,Q8TB36,Q9H300,Q99595,P55786,Q9H270,Q9P0J0,O95831,Q9Y5J9,Q9Y5J7,Q9Y5L4,O95429,O95817 13 +Lamellipodium morphogenesis 0.4168919457152642 0.2920315273102014 0.7702625188035805 1.0 1.0 4 O60749 1 +Plasma membrane organization 0.371712530200615 0.2913984983717461 0.7707465628682022 1.0 1.0 27 P10909,Q9UQB8,P31751 3 +Regulation of anaphase promoting complex dependent catabolic process 0.6743711760706779 0.2910381969280456 0.7710221063938887 1.0 1.0 2 P24941 1 +Positive regulation of transcription elongation from rna polymerase ii promoter 0.3812424827279181 0.2893955994318159 0.7722786621466038 1.0 1.0 7 P35269 1 +Membrane disassembly 0.4052398775093677 0.2893193801802393 0.7723369829489248 1.0 1.0 5 Q9ULX6,Q14203,Q99986,P53350 4 +Transmission of nerve impulse 0.3810481498022562 0.2887236800835905 0.7727928399919586 1.0 1.0 7 Q06787 1 +Germ cell development 0.3501282663473146 0.2874071162020571 0.7738006130131081 1.0 1.0 32 Q8N2A8,Q96SI9,Q96KQ7,Q12768,Q01085,Q9GZT3,Q08J23 7 +Mitotic cytokinesis 0.3338700457400527 0.2862909800630678 0.7746552660103307 1.0 1.0 35 Q13432,Q6DKK2,Q8WUX9,O95235,Q01082,Q9NZZ3,Q9Y3E7,Q02241,O95630,P16949,P61586,O75116,P25054,O75351,Q14141 15 +Protein localization to cell surface 0.3902737753369604 0.2860347019438203 0.7748515430869418 1.0 1.0 15 Q92643 1 +Negative regulation of production of molecular mediator of immune response 0.6713120326308608 0.2843475788716835 0.7761440275406817 1.0 1.0 2 P09601 1 +Protein acetylation 0.2774385643435709 0.2840948799543595 0.7763376705917298 1.0 1.0 43 Q9NRF9,Q03164,Q9UBU8 3 +Regulation of mitochondrial fusion 0.3769059483006387 0.2831535025481118 0.7770591698866607 1.0 1.0 6 Q8N2A8,Q96E52 2 +Negative regulation of intracellular steroid hormone receptor signaling pathway 0.3833948986550456 0.2822611176481252 0.7777432974846352 1.0 1.0 9 Q13547,Q9H270,P61586 3 +Regulation of organ growth 0.386462110949214 0.2821230659795656 0.7778491472184903 1.0 1.0 11 Q99956 1 +Ribosomal large subunit export from nucleus 0.3765792871742361 0.2820497006373587 0.7779054010373949 1.0 1.0 6 Q9NVU7,Q15050 2 +Inner mitochondrial membrane organization 0.3759552989977521 0.2817087677136662 0.7781668310069492 1.0 1.0 25 Q13505,Q6UXV4,Q96E52,Q9NX63,Q9P0J0,Q9Y5J9,Q9Y5J7,Q9Y5L4,Q16891,O75431,Q9NVH1 11 +Regulation of protein depolymerization 0.3536608209845827 0.2806112973228608 0.7790085500538235 1.0 1.0 31 Q66K74,P35241,Q01082,Q7Z460,P78559,Q12797,Q13813,O15344,O15020,P25054,P35611,P52907 12 +Indole containing compound metabolic process 0.4760319479702861 0.2804107748236148 0.7791623714064679 1.0 1.0 3 P05091 1 +Regulation of intrinsic apoptotic signaling pathway 0.2820394542445358 0.2802260118822938 0.7793041112161052 1.0 1.0 54 O00330,Q86TM6,Q13547,Q9H300,Q9NYF8,P10909,Q9UL15,Q8N2F6,P61978 9 +B cell activation involved in immune response 0.388650393727128 0.2797075627859606 0.7797018755818206 1.0 1.0 16 Q9UQ84 1 +Positive regulation of intracellular transport 0.2974276197271945 0.2774018700773262 0.7814715458386678 1.0 1.0 66 P27105,P35241,Q9H6U6,O75312,P55786,Q9C0E2,Q12965,Q9Y282,Q9UL25,P50402,P31751 11 +Non lytic viral release 0.3797068463175744 0.2763202398483216 0.7823021117038547 1.0 1.0 8 Q8WUX9,Q9NZZ3,Q9Y3E7,Q9UN37,O75351 5 +Positive regulation of immune system process 0.3453216406470428 0.2760984346204732 0.7824724629554389 1.0 1.0 105 P61088,P01889,P12956,O15400,P61086,P09601,Q8NHP6,O14920,Q13177,P10909,O75179,Q13951,Q8WXF1,P46379,Q9UJZ1,Q07021,Q08722,P61586,Q96IZ0,P16220,Q5JRA6,P30825,O00429,P23246,O95999,Q9NUQ9,Q9NUD5,P41240,Q8NE86,P04439,Q96PK6,Q05397 32 +Ventricular cardiac muscle tissue development 0.3760821763150628 0.2717548288822132 0.7858105397758335 1.0 1.0 7 P09493 1 +Erbb2 signaling pathway 0.4722883373002379 0.2712751276391624 0.7861794347374225 1.0 1.0 3 Q9UNE7,Q93034 2 +Regulation of dna dependent dna replication 0.3785710077033928 0.2709494720486651 0.7864298944440344 1.0 1.0 23 Q96S55,P24941,P35250,O95785,O60934,Q9UNS1,Q9BRT9 7 +Regulation of carbohydrate biosynthetic process 0.3855379026193043 0.2705400109007588 0.7867448398486891 1.0 1.0 18 P22413,Q9BYT8,P11310,Q92520,Q13043,O15294,P31751 7 +Serotonin metabolic process 0.6648538409245459 0.2705154655810944 0.7867637204915465 1.0 1.0 2 P05091 1 +Primary amino compound metabolic process 0.6648538409245459 0.2705154655810944 0.7867637204915465 1.0 1.0 2 P05091 1 +Cellular response to iron ion 0.6648538409245387 0.2705154655810791 0.7867637204915583 1.0 1.0 2 P09601 1 +Astrocyte development 0.408725787884919 0.2699632825350108 0.7871885014195326 1.0 1.0 4 P08670 1 +Histone h2a phosphorylation 0.4085034013605456 0.2693750358194456 0.787641094909957 1.0 1.0 4 Q13043,O75844,O60264 3 +Regulation of t cell proliferation 0.3857591049742259 0.2685309893334666 0.7882906244586407 1.0 1.0 15 Q96IZ0,Q92990 2 +5s class rrna transcription by rna polymerase iii 0.4081632653061167 0.2684766458280019 0.7883324491391868 1.0 1.0 4 Q9Y5Q8,Q9Y5Q9,Q12789 3 +Regulation of superoxide metabolic process 0.6634942216179518 0.2676544879443455 0.7889652852603617 1.0 1.0 2 P08754 1 +Centrosome duplication 0.3850799948067271 0.26657832351918 0.7897938471674573 1.0 1.0 17 P24941,Q9C0F1,Q9NZZ3,Q9Y3E7,Q14008,O75116,P06748,O43633,O75351,Q96PK6 10 +Second messenger mediated signaling 0.3753018262314025 0.2664623775638293 0.7898831306297998 1.0 1.0 24 O00330,P05026 2 +Positive regulation of centriole replication 0.6624745071380063 0.2655204881214739 0.7906085288655345 1.0 1.0 2 O75351 1 +Negative regulation of cell substrate adhesion 0.3800962795619625 0.2645624858496576 0.791346522549516 1.0 1.0 10 P61586,P21359,Q9H6U6 3 +Positive regulation of g1 s transition of mitotic cell cycle 0.3834518343855682 0.2635577639029104 0.7921207075360797 1.0 1.0 13 O75179,Q96DY7 2 +Response to endoplasmic reticulum stress 0.3133492761147756 0.2619410890509249 0.7933668607716065 1.0 1.0 80 Q9BUN8,Q9Y4L1,Q9Y679,P33908,O00330,Q8IXB1,Q96CS3,O95831,Q96JB5,P10909,P57088,O15027,Q96HY6,P46379,Q86TM6,Q8TCJ2,Q9BS26,O94966,Q9GZZ9,O95881,Q9NYU2 21 +Amine metabolic process 0.3839003211738654 0.2611047894947268 0.7940116982838381 1.0 1.0 16 Q96QD8 1 +Chromatin assembly or disassembly 0.3018593918298213 0.260827257334866 0.7942257234976298 1.0 1.0 71 P49321,P24941,Q9NRG0,Q9UPP1,Q66K74,Q9H7B4,Q13547,Q8NEY8,Q8TAQ2,P55209,Q9NRF9,Q01105,Q99733,P17096 14 +Positive regulation of atp dependent activity 0.3781562361988165 0.2603507346987194 0.7945932408567025 1.0 1.0 22 Q8NFQ8,Q8IXB1,P05026 3 +Mitochondrial electron transport nadh to ubiquinone 0.3781314718352135 0.2602426481623396 0.7946766087807948 1.0 1.0 22 O96000,P03886 2 +L glutamate transmembrane transport 0.3720428798128355 0.25824419461919 0.7962184519585207 1.0 1.0 7 O75915,O75746,O60831 3 +Negative regulation of inclusion body assembly 0.4665079904794401 0.2574942784350953 0.7967972315879526 1.0 1.0 3 P54652,P0DMV9 2 +Regulation of dendrite morphogenesis 0.3828134572954 0.2573065448262145 0.7969421404698178 1.0 1.0 15 Q9UL25,Q9UQB8,Q9Y4G8 3 +Nuclear transcribed mrna catabolic process 0.2739496936477216 0.2568425358135315 0.7973003323980987 1.0 1.0 50 Q15477,Q9Y5S9,Q6PGP7,A2RRP1,Q9UIV1,Q99729,Q09161,Q9Y2W1,Q9UKD2,P11940,Q9NPI6,O75175,Q9H074,P67809 14 +Homologous chromosome pairing at meiosis 0.3752297763799285 0.2539745734521511 0.7995152016230707 1.0 1.0 9 Q96KQ7,Q92791,O94901,P46379 4 +Positive regulation of mapk cascade 0.2892944184142803 0.253919591237409 0.7995576790945069 1.0 1.0 41 O14641,O60271,O60504,Q9UMX5 4 +Adipose tissue development 0.3749354693961661 0.2529757641713984 0.8002869415631739 1.0 1.0 9 P35610,Q8N0X7 2 +Rna phosphodiester bond hydrolysis endonucleolytic 0.3566183596389637 0.2516626048656964 0.8013018638168079 1.0 1.0 29 Q8N2A8,O15091,Q9UQ84,Q5TA45 4 +Negative regulation of actin filament depolymerization 0.3807184311065132 0.2510001726313959 0.8018139757197136 1.0 1.0 14 P35241,Q01082,Q13813,O15020,P35611 5 +Negative regulation of lipoprotein particle clearance 0.6549966009517368 0.2501806898173889 0.8024476178080984 1.0 1.0 2 P41240 1 +Negative regulation of low density lipoprotein particle clearance 0.6549966009517368 0.2501806898173889 0.8024476178080984 1.0 1.0 2 P41240 1 +Muscle cell development 0.3630396423268644 0.2485430217756372 0.8037142875161716 1.0 1.0 27 Q96TA1,Q9H7B4 2 +Regulation of dna demethylation 0.4624277456647522 0.2480079549656189 0.8041282518809627 1.0 1.0 3 Q13263,Q93009 2 +Axis specification 0.3686711702372134 0.2471723207377485 0.8047748656585021 1.0 1.0 7 P80723 1 +Signal release 0.2754178240165496 0.2467971555168175 0.8050652119820223 1.0 1.0 52 O00330,Q16836,Q6ZWJ1,Q96TA1,Q15042,Q8NE86,O43768,Q06787,Q4J6C6 9 +Cell differentiation involved in embryonic placenta development 0.6522773623385504 0.2447386971877806 0.8066587629882878 1.0 1.0 2 Q13043 1 +Natural killer cell differentiation 0.6522773623385503 0.2447386971877803 0.806658762988288 1.0 1.0 2 O95251 1 +Cellular response to hormone stimulus 0.3540291854994271 0.2438990802807326 0.807308981504258 1.0 1.0 116 Q9H7B4,P42785,Q9H6U6,Q9BZF1,O95831,Q9UQB8,Q9H1E3,Q96HY6,P61026,Q12965,O60763,P62993,Q9GZZ9,P31751,Q13547,Q8WWQ0,P20020,P22413,Q6ZWJ1,Q9HCD5,Q05397 21 +Negative regulation of intrinsic apoptotic signaling pathway 0.3265675793523366 0.2415867574520663 0.8091003842113298 1.0 1.0 35 O00330,Q86TM6,Q13547,Q9H300,P10909,Q9UL15,Q8N2F6 7 +Reactive oxygen species biosynthetic process 0.371520433309917 0.2414943059238006 0.8091720291291566 1.0 1.0 9 P00403,Q15067 2 +Serine phosphorylation of stat protein 0.6502379333786592 0.2407052175594913 0.809783594826212 1.0 1.0 2 Q13610 1 +Behavioral response to cocaine 0.6502379333786401 0.2407052175594543 0.8097835948262406 1.0 1.0 2 Q96KQ7 1 +Positive regulation of muscle cell differentiation 0.3688280243969934 0.2397582319475136 0.8105176886686403 1.0 1.0 8 Q96TA1 1 +Negative regulation of cyclic nucleotide phosphodiesterase activity 0.6492182188987052 0.2387039639422419 0.8113351428188371 1.0 1.0 2 Q15043 1 +Protein k11 linked ubiquitination 0.3725289706884669 0.2385361507150033 0.811465280177625 1.0 1.0 10 Q13042,Q9UJX2,Q9UJX3,Q9UJX4,Q16763,P30260,Q9UJX5,Q9H1A4,P68036 9 +Negative regulation of cell differentiation 0.2964693090461955 0.237527654182271 0.8122474680310212 1.0 1.0 69 Q13547,Q8N4Q0,O60271,Q9UPY3,O75179,Q9Y4G8,Q8N0X7,P67809 8 +Plasma membrane raft organization 0.6478585995921196 0.236051725719497 0.8133925327300298 1.0 1.0 2 Q9UNF0 1 +Plasma membrane raft assembly 0.6478585995921196 0.236051725719497 0.8133925327300298 1.0 1.0 2 Q9UNF0 1 +Vascular endothelial growth factor receptor signaling pathway 0.3697098103405625 0.2354888156316613 0.8138293586390153 1.0 1.0 9 O14964,Q96TA1,P49137,Q05397 4 +Thrombin activated receptor signaling pathway 0.4568118048305213 0.2352832485642245 0.8139888959303794 1.0 1.0 3 P16949 1 +Positive regulation of fatty acid transport 0.6468388851121739 0.2340746444023057 0.8149270300030329 1.0 1.0 2 P33121 1 +Odontogenesis of dentin containing tooth 0.36424244967721 0.2329209926861072 0.8158227569099117 1.0 1.0 7 Q13547,Q6P4Q7,P35613 3 +Centriole centriole cohesion 0.4555582775653261 0.2324960518428168 0.816152753387045 1.0 1.0 3 Q9C0F1 1 +Presynaptic modulation of chemical synaptic transmission 0.6458191706322283 0.2321079508938554 0.8164541695813476 1.0 1.0 2 Q00535 1 +Response to electrical stimulus 0.3611300204220574 0.2318122265499876 0.8166838602884565 1.0 1.0 6 Q14103,Q7L576,P04179,O95696,Q02952 5 +Regulation of hematopoietic stem cell proliferation 0.6454792658055797 0.2314546976215865 0.8169615759775857 1.0 1.0 2 O95251 1 +Osteoblast proliferation 0.6454792658055744 0.2314546976215762 0.8169615759775937 1.0 1.0 2 P61586 1 +Regulation of osteoblast proliferation 0.6454792658055744 0.2314546976215762 0.8169615759775937 1.0 1.0 2 P61586 1 +Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.6447994561522619 0.2301516614824432 0.8179739221293989 1.0 1.0 2 P23634 1 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.6437797416723372 0.2282057919921367 0.8194862588766212 1.0 1.0 2 Q13177 1 +Negative regulation of cytokine production 0.3686543234885464 0.2272768273629662 0.8202084907381533 1.0 1.0 23 P20020,Q07021,Q9BWS9,Q9Y5K6,P31483,Q9UPY3,Q96RT1,P09525,P09601 9 +Ribonucleoside triphosphate biosynthetic process 0.3552980030487771 0.2270931892102924 0.8203512799345931 1.0 1.0 28 P00846 1 +Mesenchymal cell proliferation 0.3916512957533976 0.2268313828174307 0.820554859716567 1.0 1.0 4 P42224 1 +Positive regulation of protein localization to centrosome 0.4522198809616773 0.225168539599726 0.8218481627873016 1.0 1.0 3 P25054 1 +Connective tissue replacement 0.6420802175390878 0.2249858730470443 0.821990264224054 1.0 1.0 2 O75116 1 +Positive regulation of connective tissue replacement 0.6420802175390878 0.2249858730470443 0.821990264224054 1.0 1.0 2 O75116 1 +Regulation of connective tissue replacement 0.6420802175390878 0.2249858730470443 0.821990264224054 1.0 1.0 2 O75116 1 +Positive regulation of tissue remodeling 0.6420802175390878 0.2249858730470443 0.821990264224054 1.0 1.0 2 O75116 1 +Cellular response to vitamin 0.382522842266892 0.2249192494592901 0.8220420940360615 1.0 1.0 5 P20020,Q8TB36 2 +Negative regulation of smooth muscle cell migration 0.3908041060088384 0.2248009011991124 0.8221341649657856 1.0 1.0 4 P09493 1 +Cellular response to alcohol 0.3712968774120424 0.2240722109627495 0.8227011151653265 1.0 1.0 12 O95831 1 +Rap protein signal transduction 0.3821289488239814 0.2238702960411914 0.8228582294569797 1.0 1.0 5 Q9Y4G8 1 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.4508670520231297 0.222238866599654 0.8241279393673708 1.0 1.0 3 Q16543,O95140 2 +Protein localization to nucleolus 0.3633701988285931 0.2221753109063694 0.8241774128703625 1.0 1.0 8 Q68CQ4,Q76FK4,Q15050 3 +Leukocyte chemotaxis 0.36284063650114 0.2211171735536232 0.8250011986349324 1.0 1.0 25 Q8NHP6,Q8NE86 2 +Arf protein signal transduction 0.6397008837525547 0.2205268132335041 0.8254608923908253 1.0 1.0 2 Q92538 1 +Skeletal muscle cell differentiation 0.3628103894310445 0.2204015116069602 0.8255584682644401 1.0 1.0 8 P50402,Q8NC56 2 +Response to amyloid beta 0.3887755102040762 0.219981964394314 0.8258852009967306 1.0 1.0 4 P49841,P09874,Q00535 3 +Cellular response to amyloid beta 0.3887755102040762 0.219981964394314 0.8258852009967306 1.0 1.0 4 P49841,P09874,Q00535 3 +Regulation of cell junction assembly 0.3422410958640383 0.2192404381290755 0.8264627565699245 1.0 1.0 31 O14920,Q12965,Q05397,Q9H6U6 4 +Amino acid transport 0.3699040367007388 0.2190560776421742 0.826606364758059 1.0 1.0 21 Q96EV8,O60831,P08195,Q9Y619,P21359,Q15042,Q96QD8,O75915,O75746,P30825 10 +Regulation of dendritic spine development 0.3724077718556406 0.2189500444442182 0.8266889622825206 1.0 1.0 15 Q96EV8,Q06787,Q9UQB8 3 +Odontogenesis 0.365193905976137 0.2142731557819378 0.830334050469655 1.0 1.0 10 Q13547,P61586,Q6P4Q7,P35613 4 +Regulation of striated muscle cell differentiation 0.3683831993360631 0.2141983201812406 0.8303924059857173 1.0 1.0 12 Q96TA1,P67809 2 +Regulation of jun kinase activity 0.3575644505330952 0.2120751828596353 0.8320483805466359 1.0 1.0 7 O14641 1 +Cardiac left ventricle morphogenesis 0.6346023113528269 0.2111642388050827 0.8327591148371987 1.0 1.0 2 P49840 1 +Endocardium development 0.6346023113528269 0.2111642388050827 0.8327591148371987 1.0 1.0 2 Q13043 1 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.3770588094967857 0.2105828506485108 0.833212795436802 1.0 1.0 5 P09493 1 +Caveolin mediated endocytosis 0.3765657065053405 0.2093119687009972 0.8342047090409572 1.0 1.0 5 Q13432 1 +Mitochondrial protein processing 0.3563488669008749 0.2083657908334555 0.834943365060312 1.0 1.0 7 Q9Y4W6,Q9UJZ1,Q96E52 3 +Ear morphogenesis 0.3685272423421311 0.2074714968821837 0.8356416505707878 1.0 1.0 14 Q13308,P54802 2 +Cytoplasmic translational elongation 0.3823127528535126 0.2050382621745445 0.8375422311377365 1.0 1.0 4 O60524 1 +Embryonic morphogenesis 0.2871917319676933 0.2041438488398995 0.8382410893491463 1.0 1.0 65 Q13308,O00330,Q13547,Q92990,Q4VCS5,O94788,O14641,P62993,O60701,P54802,P67809 11 +Positive regulation of dna binding transcription factor activity 0.3254042855202007 0.2039357802719288 0.8384036839841882 1.0 1.0 34 O14920,P19474,O14641,P10909,Q96HY6 5 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.3575011876927955 0.2038591652173345 0.8384635563553924 1.0 1.0 8 P61978 1 +Positive regulation of receptor recycling 0.3816326530612226 0.2035021485341703 0.8387425665300636 1.0 1.0 4 P07355,Q14160,P42892 3 +Regulation of endodeoxyribonuclease activity 0.4406664399864097 0.2008938603246924 0.8407815685998883 1.0 1.0 3 P06748,P23396 2 +Positive regulation of vascular endothelial cell proliferation 0.4406664399864029 0.2008938603246785 0.8407815685998992 1.0 1.0 3 P40763,P19174 2 +Vascular endothelial cell proliferation 0.4406664399864029 0.2008938603246785 0.8407815685998992 1.0 1.0 3 P40763,P19174 2 +Eating behavior 0.6288239292998019 0.2008722539794842 0.8407984636160575 1.0 1.0 2 P50416 1 +Regulation of histone methylation 0.3576438897227639 0.1982455596709853 0.8428529433218523 1.0 1.0 25 Q96KQ7,Q5VTR2,Q03164 3 +Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6271244051665592 0.197909932786661 0.8431155326510091 1.0 1.0 2 P23396 1 +Protein localization to plasma membrane 0.2915251442037668 0.197872762086137 0.8431446155106606 1.0 1.0 69 O00264,O14920,O14976,Q9HD26,P05026,O15400,P31751,Q4J6C6 8 +Atp synthesis coupled electron transport 0.3016891064630485 0.1975880959820856 0.8433673492160239 1.0 1.0 38 P00403,O96000,P03886 3 +Regulation of synaptic transmission glutamatergic 0.3710736050847034 0.1954170359525288 0.8450664809408606 1.0 1.0 5 Q15042 1 +Glycerolipid biosynthetic process 0.3013451773185337 0.1954058289136703 0.8450752537571615 1.0 1.0 38 Q92643,Q8WTV0,Q9NPH0 3 +Interleukin 8 production 0.3570578959004676 0.1951645518850052 0.8452641289160991 1.0 1.0 9 P09525 1 +Regulation of membrane depolarization during action potential 0.6250849762066679 0.1943940763846946 0.8458673278142839 1.0 1.0 2 Q9HD47 1 +Membrane depolarization during cardiac muscle cell action potential 0.6250849762066679 0.1943940763846946 0.8458673278142839 1.0 1.0 2 Q9HD47 1 +Regulation of membrane depolarization during cardiac muscle cell action potential 0.6250849762066679 0.1943940763846946 0.8458673278142839 1.0 1.0 2 Q9HD47 1 +Regulation of protein localization to membrane 0.3011719065615054 0.1943083117915854 0.8459344777998041 1.0 1.0 38 P27105,O00264,Q01082,Q12965,Q9HD26,O15400,P31751,Q15334 8 +Nucleoside triphosphate catabolic process 0.3706170338759249 0.1942835532061536 0.8459538629148837 1.0 1.0 5 Q9H773 1 +Intraciliary transport involved in cilium assembly 0.6247450713800138 0.1938122325422507 0.8463229084447244 1.0 1.0 2 A0AVF1 1 +Regulation of organic acid transport 0.35843545518597 0.1927942761330913 0.8471200863781345 1.0 1.0 10 P05556,Q96EV8,P14174,Q15042,P31751,O75915,P33121 7 +Dna templated transcription elongation 0.3180747910408035 0.1918630664244988 0.8478494686379598 1.0 1.0 35 P35269,Q8IXH7,P13984,Q9NPA8,O43719,Q5BKZ1,P18074,O60885,Q14241 9 +Phosphatidylglycerol acyl chain remodeling 0.6230455472467744 0.1909207356958993 0.848587694251072 1.0 1.0 2 Q92604 1 +Folic acid containing compound catabolic process 0.4348860931655913 0.1893893578765293 0.8497876647208435 1.0 1.0 3 P49914,Q9NRN7 2 +Neuron projection guidance 0.3624264851716883 0.1893164734406539 0.8498447848454993 1.0 1.0 21 O00264,Q96TA1,Q05397 3 +Negative regulation of actin filament polymerization 0.3642568160315486 0.1884665962624878 0.8505108985977512 1.0 1.0 18 P35241,Q9NUQ9,Q01082,Q13813,O15020,P35611 6 +Regulation of vesicle size 0.3679223187766541 0.1876619355343478 0.8511416711049593 1.0 1.0 5 Q12768 1 +Cardioblast differentiation 0.6206662134602371 0.186922295884276 0.8517215577038613 1.0 1.0 2 Q06330 1 +Mrna transport 0.2926052932804157 0.186399155842158 0.8521317543700149 1.0 1.0 71 Q86U42,Q8N1F7,Q06787,P51991,Q5SRE5,Q09161,Q9NPA8,P84103,Q12965,Q9UN86,Q8TD16,Q96PU8,Q07955,Q8NFH5,P12270,Q08J23 16 +Positive regulation of kinase activity 0.2849352734629502 0.1863371179753399 0.852180401220082 1.0 1.0 65 Q13432,O95999,Q15334,Q92878,Q99627,O60934,Q9BZF1,Q13177,Q13043,P61586,P12956,P41240,O14641,P10909,Q9Y4G8,Q05397,P23634,Q96M27 18 +Immunoglobulin production 0.3599118449022348 0.1843875634519926 0.8537094254789583 1.0 1.0 22 Q9UQ84 1 +Regulation of epithelial cell differentiation 0.3624172035575903 0.1841239012616196 0.853916256525346 1.0 1.0 15 Q13247,P42224,P35611,O14920 4 +Muscle tissue development 0.2702426674398592 0.1833470966892453 0.8545256828476337 1.0 1.0 54 P09493,Q96TA1,O94788,P11310,P62942,Q9NQ29,O94966 7 +Phosphatidylcholine metabolic process 0.3531074468802999 0.1831810915452549 0.8546559300964294 1.0 1.0 9 Q8WTV0 1 +Protein refolding 0.3586227299814386 0.182307603873418 0.8553413316555971 1.0 1.0 12 P48723,P62942,P0DMV9,P11142,Q0VDF9,P08621,P54652,Q9UL15 8 +Smooth muscle cell proliferation 0.3622330204574675 0.1811570040375645 0.8562443419563714 1.0 1.0 18 Q13547,P42224,P09493,P61586,P12956,Q15637,P09601 7 +Neural tube development 0.3536092047865773 0.1809618868477604 0.8563974919414479 1.0 1.0 25 Q13308,O94788,Q92990 3 +Metanephric epithelium development 0.3644784303296118 0.1793705014751423 0.8576467921443909 1.0 1.0 5 P35610 1 +Leukocyte proliferation 0.3103598847254045 0.1786783960244824 0.8581902336529188 1.0 1.0 36 Q92990,Q96IZ0,P10909,P04439,Q05397 5 +Positive regulation of protein k63 linked ubiquitination 0.6152277362338492 0.1780007730879704 0.8587223686002226 1.0 1.0 2 P61088 1 +Aspartate transmembrane transport 0.4284257055423381 0.1770434951556004 0.8594742249835272 1.0 1.0 3 O75746,Q9H936 2 +Recombinational repair 0.2613224062869826 0.175673864352688 0.8605501691777169 1.0 1.0 48 P15927,O60934,Q7Z4V5,Q9UBU8,Q14566,P33991,Q9UNS1,P35637,Q9H1E3 9 +Circadian regulation of gene expression 0.3601287499035668 0.1745648689467522 0.8614215551766309 1.0 1.0 16 Q13547,P43490,Q03164,Q13330 4 +Polysaccharide biosynthetic process 0.3597020368236797 0.1731177704574023 0.8625588570397094 1.0 1.0 16 P11310,P22413,P31751 3 +Positive regulation of g protein coupled receptor signaling pathway 0.3673469387755146 0.1728664302311481 0.8627564191496846 1.0 1.0 4 P35232,Q15043,P49840 3 +Positive regulation of blood pressure 0.4255401878465709 0.171704953212517 0.8636694915520933 1.0 1.0 3 P09493 1 +Gland development 0.2842197593364697 0.170812354970829 0.8643713139896987 1.0 1.0 66 O00330,O94788,P07602,P00403,P35610,P31751 6 +Male gamete generation 0.2854169914818149 0.1701762483599931 0.8648715303142345 1.0 1.0 67 Q9Y508,Q8N2A8,Q96SI9,Q14141,Q9P0K7,Q96KQ7,Q16181,Q96PU8,Q14320,Q9GZT3,Q15067,Q15102,P23634,Q08J23,P46379 15 +Regulation of defense response to virus by host 0.3400272294077684 0.169868787162953 0.8651133285655126 1.0 1.0 6 P42224,P07900,Q8TDB6,O94826,O60828 5 +Regulation of protein localization to cell surface 0.3485711527628603 0.1697894483409079 0.8651757254440406 1.0 1.0 9 Q9HD26 1 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.3508314321246379 0.1696721038941221 0.865268013799882 1.0 1.0 10 P10909 1 +Regulation of actin filament organization 0.2788834075296114 0.1693563937469742 0.8655163207392986 1.0 1.0 62 P35241,Q12768,Q01082,Q14019,Q13177,Q7Z460,P35611,Q9UQB8,O60504,Q14247,Q08722,P16949,P61586,O15020,P62993,P09493,Q9NUQ9,O95429,Q13813,O75116 20 +Positive regulation of protein kinase b signaling 0.358862842721496 0.1692488324424694 0.8656009210482889 1.0 1.0 17 Q86UE4,Q9BZF1,Q07021,Q05397 4 +Regulation of transcription regulatory region dna binding 0.3451408757296902 0.167371800996869 0.8670775117254983 1.0 1.0 8 Q96TA1 1 +Vesicle docking 0.3571785141283468 0.1666866256968986 0.8676166294539394 1.0 1.0 15 O15400,O60763,P61026 3 +Nadh dehydrogenase complex assembly 0.3478785804718827 0.166666825780813 0.8676322095745452 1.0 1.0 26 O96000,P03886 2 +Meiotic cell cycle checkpoint signaling 0.4225363318631817 0.1662631701446505 0.8679498485599066 1.0 1.0 3 Q08J23 1 +Positive regulation of hydrolase activity 0.308615595496677 0.1658360339669968 0.8682859877345328 1.0 1.0 86 Q13526,O95999,Q9H6U6,Q8WU90,Q9Y4G8,O95831,Q9NR28,P07602,Q15404,Q15042,O14641,Q9Y263,Q66K14,Q96HY6,P31751,Q9BXK5 16 +Developmental maturation 0.2770201312045414 0.1657464273303459 0.8683565076153839 1.0 1.0 41 Q8N2A8,Q12768,O94788,P18074,O75179,Q08J23 6 +Positive regulation of microtubule nucleation 0.3586253827832618 0.1657240774456616 0.8683740970026144 1.0 1.0 5 P51608,P0DMV9,Q14203,Q14008 4 +Carboxylic acid transport 0.327517155804056 0.1656401615860221 0.8684401394706764 1.0 1.0 32 Q96EV8,O60831,Q9H2D1,P08195,Q9Y619,P07602,Q15042,Q96QD8,O75915,Q9BQT8,P30825 11 +Nucleoside triphosphate biosynthetic process 0.3230756773644509 0.1654398610670496 0.8685977813275876 1.0 1.0 33 P00403,P55263,P00846 3 +Multivesicular body organization 0.3567550630617931 0.1653026209875915 0.8687057959509945 1.0 1.0 15 O14964,P53990,Q9NP79,Q8WUX9,Q92783,Q9NZZ3,Q9Y3E7,O75351 8 +T cell receptor signaling pathway 0.3568800938273332 0.1649856421180404 0.8689552831145713 1.0 1.0 20 Q9UJZ1,O95999,O14920,Q96IZ0,P41240,P04439 6 +Telomere capping 0.344180418246163 0.1646585395264946 0.869212752118435 1.0 1.0 8 Q92878,O60934,Q93009,P49959 4 +Entry into host 0.3532148452499992 0.1638314677113265 0.8698638187166883 1.0 1.0 23 P19474 1 +Positive regulation of membrane potential 0.3572065215948553 0.1625011634840209 0.870911212126317 1.0 1.0 5 P31751 1 +Peptidyl lysine acetylation 0.3019345486753078 0.1623914148548717 0.8709976310615548 1.0 1.0 37 Q9NRF9,Q03164,Q9UBU8 3 +Detection of abiotic stimulus 0.3431643130583267 0.1618076005030084 0.8714573675848674 1.0 1.0 8 Q05397 1 +Regulation of heterotypic cell cell adhesion 0.6043507817811076 0.1610670934416387 0.872040557440495 1.0 1.0 2 O75955 1 +Cellular pigmentation 0.345485519591126 0.16090948878093 0.8721646887287096 1.0 1.0 9 Q96EV8,O00203,Q9BXS5,Q9H267,Q13561,O14617,O95295,O43747 8 +Positive regulation of i kappab kinase nf kappab signaling 0.322184934468213 0.1608393847749726 0.8722199044817471 1.0 1.0 33 O95999,O60885,O14920,O43657,Q86UE4,P62942,P61586,P19474,O75179,Q99584,P09601 11 +Cytokine production 0.3042709765139734 0.1608238793875718 0.8722321170154637 1.0 1.0 83 P01889,Q01082,P31483,P19474,P09601,P49137,Q92990,Q9BWS9,P10909,Q9UJZ1,Q07021,Q9Y5K6,Q08722,Q9UPY3,P09525,P42224,P20020,O95999,Q9NUQ9,Q9NUD5,P41240,Q96RT1,P04439,Q99584 24 +Execution phase of apoptosis 0.3529132825431099 0.1599078652853765 0.8729536526501744 1.0 1.0 13 Q9UPY3,O95831 2 +Protein targeting to membrane 0.3341938405902983 0.159852057025809 0.8729976157097237 1.0 1.0 30 P27105,O60725,Q9UGP8,Q9NT62,P43307,Q12965,P40855,P08240,P31751,P46379 10 +Negative regulation of cell activation 0.3547122056318968 0.1586799800711669 0.8739210119035699 1.0 1.0 15 P09601,Q13951,Q96IZ0,Q92990 4 +Transcription elongation from rna polymerase ii promoter 0.3499986795533513 0.1577921377358585 0.8746205942206478 1.0 1.0 24 P35269,Q8IXH7,P13984,Q9NPA8,O60885,Q14241 6 +Chromatin remodeling 0.2963983715009912 0.1575665439425772 0.8747983682534564 1.0 1.0 77 Q13547,Q9NRG0,P49321,Q9H7B4,Q8WXI9,P55209,Q9UEE9,Q9NRF9,Q01105,Q99733,P17096,O60885,Q13330 13 +Viral gene expression 0.3168839431402334 0.1575205323706089 0.8748346273972996 1.0 1.0 34 Q13724,P41214,Q10472,P19474,Q9H1E3 5 +Regulation of mesenchymal cell proliferation 0.4166291142486468 0.1559067368810183 0.8761065349853767 1.0 1.0 3 P42224 1 +Regulation of cell migration involved in sprouting angiogenesis 0.415885733803386 0.1546359045582906 0.8771083627018188 1.0 1.0 3 P09601 1 +Release of cytochrome c from mitochondria 0.3544994843747888 0.1544656603080782 0.8772425853327064 1.0 1.0 17 P10909 1 +Regulation of protein localization to plasma membrane 0.3505032951281128 0.1533014367649409 0.8781605676940225 1.0 1.0 23 Q01082,O15400,Q9HD26,O00264 4 +Positive regulation of histone modification 0.3159917376845815 0.1528145544775296 0.8785445197332475 1.0 1.0 34 P61088,O75150,Q5VTR2,Q03164,O60885,O95251,Q06787,Q13573 8 +Inositol lipid mediated signaling 0.3538656121165742 0.1523537243119901 0.8789079535650375 1.0 1.0 17 Q8NEB9,Q07021,O95630,P21359,O15294,Q9NV70,Q05397 7 +Regulation of glial cell apoptotic process 0.5982324949014342 0.1520737576123981 0.8791287618417396 1.0 1.0 2 Q00535 1 +Positive regulation of protein kinase a signaling 0.5982324949014342 0.1520737576123981 0.8791287618417396 1.0 1.0 2 P14174 1 +Protein kinase c signaling 0.5982324949014342 0.1520737576123981 0.8791287618417396 1.0 1.0 2 O75955 1 +Iron ion homeostasis 0.3532570500656408 0.1503347026121506 0.8805005553681273 1.0 1.0 17 Q8N511 1 +Negative regulation of transmembrane transport 0.3493990617997871 0.1490679306121959 0.8815000307781315 1.0 1.0 23 Q06787,P62942,P31751,Q9HD26 4 +Establishment or maintenance of monopolar cell polarity 0.3410884556646756 0.1485811551288049 0.881884143963404 1.0 1.0 9 Q13308,P46821,P61586 3 +Regulation of chromatin assembly 0.347088380608252 0.1470754685795931 0.883072452529666 1.0 1.0 12 P24941,Q9UPP1,Q8NEY8 3 +Regulation of lymphocyte migration 0.3500816326069886 0.1468246941358811 0.883270392813039 1.0 1.0 5 Q5JRA6 1 +Regulation of t cell activation 0.3148338954875828 0.1467525486683436 0.8833273397361601 1.0 1.0 34 O95999,Q92990,Q9NUQ9,Q08722,P61586,Q96IZ0,O43290,P41240,P04439,Q13951,P30825 11 +Endoplasmic reticulum plasma membrane tethering 0.4110846650799059 0.1466031274776235 0.8834452849885279 1.0 1.0 3 A0FGR8,O95292 2 +Endoplasmic reticulum localization 0.4110846650799059 0.1466031274776235 0.8834452849885279 1.0 1.0 3 A0FGR8,O95292 2 +Skeletal muscle adaptation 0.5941536369816509 0.1462900609734303 0.8836924116444735 1.0 1.0 2 Q13555 1 +Regulation of skeletal muscle adaptation 0.5941536369816509 0.1462900609734303 0.8836924116444735 1.0 1.0 2 Q13555 1 +Positive regulation of receptor catabolic process 0.5938137321550034 0.145815713202382 0.8840668711479251 1.0 1.0 2 Q8TDB6 1 +Growth hormone receptor signaling pathway via jak stat 0.5938137321550033 0.1458157132023817 0.8840668711479254 1.0 1.0 2 P40763 1 +Retina development in camera type eye 0.3511796125604506 0.1450509298785766 0.884670660724961 1.0 1.0 16 Q96EV8,P20020,P54802 3 +Positive regulation of axon extension 0.3418541240627072 0.1438480723041748 0.8856204413872077 1.0 1.0 10 P46821,P78344,Q9UJU6,Q7L576,Q9UPN3,Q9H2P0,P31150,P43034,Q9UJX6 9 +Regulation of intracellular estrogen receptor signaling pathway 0.3487200083102909 0.1430857128825789 0.8862224883029304 1.0 1.0 14 Q9H270,Q9GZZ9,Q96HY6 3 +Peptidyl tyrosine modification 0.2927629313750128 0.1426322185282477 0.8865806509187115 1.0 1.0 38 O95684,Q9UIV1,Q05397 3 +Positive regulation of dna recombination 0.3489646520810318 0.1425949736634005 0.8866100673500497 1.0 1.0 22 Q9UBU8,P35637,Q9UNS1,P18074 4 +Amino acid import across plasma membrane 0.3296920443446284 0.1425583624225891 0.8866389834899535 1.0 1.0 6 O75915,P08195,P30825 3 +Activation of gtpase activity 0.349507552888039 0.14221806117247 0.8869077660420746 1.0 1.0 15 P31751,Q9H6U6 2 +Dopamine receptor signaling pathway 0.3359216035351667 0.1420743246445641 0.8870212983937169 1.0 1.0 8 Q92542 1 +Regulation of ribonuclease activity 0.591094493541815 0.1420630663382039 0.8870301910259024 1.0 1.0 2 P06748 1 +Transcription initiation from rna polymerase iii promoter 0.4080244814688866 0.141640979280909 0.8873635964474453 1.0 1.0 3 Q9Y5Q8,Q12789 2 +Phosphatidylinositol 3 kinase signaling 0.3431722224565213 0.1413225527047449 0.8876151339305187 1.0 1.0 11 O95630,P21359,Q07021,Q05397 4 +Positive regulation of clathrin dependent endocytosis 0.590414683888518 0.1411365918813298 0.8877620368232206 1.0 1.0 2 Q6P3W7 1 +Regulation of actin filament bundle assembly 0.3456893039488504 0.1408988217864594 0.8879498729406927 1.0 1.0 24 O60504,P09493,P35241,Q7Z460,Q08722,P16949,P61586,O95429,O75116 9 +Intracellular protein transmembrane transport 0.3500473801694079 0.140595501093945 0.8881895025409259 1.0 1.0 20 O75298,O95831 2 +Lipoprotein metabolic process 0.3500024104099553 0.1404387419010014 0.8883133495418924 1.0 1.0 20 Q5H8A4,Q9H2M9,Q92643,Q9BQE5,Q15042,Q9NUJ1 6 +Copper ion transmembrane transport 0.589734874235221 0.1402147845357756 0.888490290931397 1.0 1.0 2 Q04656 1 +Copper ion import 0.589734874235221 0.1402147845357756 0.888490290931397 1.0 1.0 2 Q04656 1 +Antimicrobial humoral response 0.3465538149029483 0.1393781640924517 0.8891513264589221 1.0 1.0 5 P04439 1 +Plasma membrane repair 0.334771826451014 0.1390375214147355 0.8894204991890122 1.0 1.0 8 P35579,Q9NZZ3,Q8WUX9,Q9Y3E7 4 +Glycosyl compound biosynthetic process 0.3278541189184025 0.1379186006208191 0.8903047497233669 1.0 1.0 6 P55263 1 +Nucleobase containing small molecule biosynthetic process 0.3278541189184025 0.1379186006208191 0.8903047497233669 1.0 1.0 6 P55263 1 +Purine nucleoside biosynthetic process 0.3278541189184025 0.1379186006208191 0.8903047497233669 1.0 1.0 6 P55263 1 +Arginine catabolic process 0.3487179705548765 0.1376706250603343 0.8905007361023938 1.0 1.0 4 P23634 1 +Arginine metabolic process 0.3487179705548765 0.1376706250603343 0.8905007361023938 1.0 1.0 4 P23634 1 +Regulation of filopodium assembly 0.3418325565026721 0.137550535819949 0.8905956505037547 1.0 1.0 11 Q06787,Q9H6U6 2 +Somatic diversification of immune receptors 0.3462779797186234 0.1372755207090171 0.8908130188840087 1.0 1.0 23 Q9UQ84 1 +Corpus callosum development 0.4049642978578753 0.1368016205032782 0.8911876027115122 1.0 1.0 3 Q96P11,Q00535 2 +Osteoclast development 0.4049642978578694 0.1368016205032692 0.8911876027115193 1.0 1.0 3 P07355,Q15904 2 +Terminal button organization 0.5866757307953842 0.1361242943421877 0.8917230221785648 1.0 1.0 2 O95295 1 +Regulation of presynapse organization 0.5866757307953842 0.1361242943421877 0.8917230221785648 1.0 1.0 2 Q04637 1 +Regulation of bmp signaling pathway 0.3432279791684569 0.1359003224547342 0.8919000805592951 1.0 1.0 12 Q8N0X7,Q05D32,Q9Y2U8 3 +Dna geometric change 0.2601024189238425 0.1357341996956196 0.8920314104634528 1.0 1.0 51 Q96S55,P35250,Q92878,O60934,P13984,Q14566,P33991,P51530,P18074,P17096,Q9BRT9 11 +Regulation of small gtpase mediated signal transduction 0.3344975851902335 0.1323639228443063 0.8946964489523574 1.0 1.0 28 P35241,Q96RT1,Q9NUQ9,Q4VCS5,Q92538,Q9Y5K6,O95630,P16949,Q9UQ13,P21359,O15294,O95140,P52565 13 +Sodium ion transport 0.3416220235695599 0.1321826630390687 0.8948398136797178 1.0 1.0 25 Q6P4Q7,P27105,P05026,Q96QD8 4 +Cellular response to exogenous dsrna 0.3429846550314646 0.1320584160381305 0.8949380869682046 1.0 1.0 5 Q9NUD5,O60828 2 +Membrane to membrane docking 0.4015640938456342 0.1315682886250934 0.8953257694433303 1.0 1.0 3 Q13464,P15311 2 +Leukocyte adhesion to vascular endothelial cell 0.3444412592526816 0.1303564833770508 0.8962843939785354 1.0 1.0 4 P05556,P61586 2 +Regulation of receptor recycling 0.3247106875425523 0.1301371083358521 0.8964579515404787 1.0 1.0 6 Q14160,Q9NZZ3,P07355,P46459,P42892 5 +Smooth muscle cell apoptotic process 0.324279398282321 0.1290846859005446 0.8972906395027083 1.0 1.0 6 P98175,P42771 2 +Microtubule anchoring at centrosome 0.3991839510370628 0.1279947577386524 0.8981531216372904 1.0 1.0 3 Q15154,Q14203 2 +Regulation of embryonic development 0.3466256556447434 0.1278627855396265 0.89825756208685 1.0 1.0 19 Q68CQ4,Q9Y4C8,Q4VCS5,Q96TA1,Q16181,P46379 6 +Fluid transport 0.580217539089062 0.1277970216036451 0.898309607153404 1.0 1.0 2 Q99797 1 +Anterior posterior pattern specification 0.3465174502027505 0.1275631329708605 0.8984947083377262 1.0 1.0 18 O94788,P80723 2 +Protein localization to lysosome 0.343481151918642 0.1274536325466604 0.8985813696774947 1.0 1.0 14 O14964,Q7Z3T8,P10909,O75116 4 +Negative regulation of developmental growth 0.3331019495381143 0.1271856105635175 0.898793493994801 1.0 1.0 9 Q8N0X7 1 +Dna strand elongation 0.3455649983079104 0.1271408436130924 0.8988289252220709 1.0 1.0 21 O60934,Q9NRF9,P33991,P51530,Q9H1E3 5 +Negative regulation of cation channel activity 0.3299428184932799 0.1265736559974679 0.8992778486769069 1.0 1.0 8 Q06787 1 +Regulation of rna export from nucleus 0.3298893747565299 0.1264383555891905 0.8993849423942992 1.0 1.0 8 P12270,Q08J23 2 +Interferon alpha production 0.3399115345355521 0.1259290265811073 0.899788105683422 1.0 1.0 5 P42224,Q9H2U1,O00571,P10809 4 +Positive regulation of interferon alpha production 0.3399115345355521 0.1259290265811073 0.899788105683422 1.0 1.0 5 P42224,Q9H2U1,O00571,P10809 4 +Epithelial cell proliferation 0.2569674403641414 0.1256857328877583 0.8999806958081729 1.0 1.0 43 P42224,Q6ZWJ1,Q9H2J4,O94788,Q13247,Q92542,P09601,Q8WTV0,Q00577 9 +Establishment of protein localization to vacuole 0.3452261845708337 0.1244898466622256 0.9009274390343648 1.0 1.0 17 O14964,Q5THJ4,P10909 3 +Regulation of hormone secretion 0.3396156723143385 0.1244092105455203 0.9009912810452664 1.0 1.0 25 O00330,Q16836,Q8NE86,O43768 4 +Regulation of actomyosin structure organization 0.3438020349738351 0.123946231488071 0.9013578477121116 1.0 1.0 22 O60504,P09493,Q7Z460,Q08722,P16949,P61586,O95429,O75116 8 +Peptidyl arginine methylation 0.3382102756039428 0.122604838613462 0.9024200226960116 1.0 1.0 5 Q86X55,Q7L592,O60678,O14744 4 +Peptidyl arginine n methylation 0.3382102756039428 0.122604838613462 0.9024200226960116 1.0 1.0 5 Q86X55,Q7L592,O60678,O14744 4 +Regulation of cellular ph 0.3433331866140602 0.1222873097046481 0.9026714819559872 1.0 1.0 22 Q9HC07 1 +Regulation of ph 0.3433331866140602 0.1222873097046481 0.9026714819559872 1.0 1.0 22 Q9HC07 1 +Regulation of organelle assembly 0.2609230995224991 0.1222649247541356 0.9026892095392652 1.0 1.0 53 P35241,Q92783,Q96KQ7,Q9H2M9,Q9H270,Q16181,Q9UN86,Q9NT62,Q9Y3E7,Q8TC07,Q15042,P12270,Q96PK6,Q66K14 14 +Intermediate filament bundle assembly 0.5754588715159826 0.1219266470185737 0.9029571117994286 1.0 1.0 2 P07197 1 +Receptor recycling 0.3248212461695481 0.1218771449308309 0.9029963163747136 1.0 1.0 7 P49069,Q14160,Q9NZZ3,P07355,P46459,P42892 6 +Regulation of calcium ion export across plasma membrane 0.5751189666893342 0.1215158921515788 0.9032824278628486 1.0 1.0 2 P0DP25 1 +Taxis 0.2684931139119204 0.1203953408535668 0.9041699820174632 1.0 1.0 59 O00264,Q8NHP6,Q9NUQ9,Q4VCS5,Q96TA1,Q13509,Q8NE86,Q05397 8 +Homologous chromosome segregation 0.3354861569802185 0.1201938798096185 0.9043295658342774 1.0 1.0 11 Q96KQ7,Q92791,O94901,P46379 4 +Lipoprotein biosynthetic process 0.3408528046390918 0.119839717882416 0.9046101183295084 1.0 1.0 14 Q9H2M9,Q15042,Q92643 3 +Leukocyte migration 0.2561333645695223 0.1197606310683105 0.9046727692746964 1.0 1.0 43 Q8NHP6,Q08722,Q05397,Q8NE86 4 +Regulation of leukocyte proliferation 0.3423740077748615 0.1189116436528032 0.9053453569158398 1.0 1.0 22 Q96IZ0,Q92990,Q05397 3 +Filopodium assembly 0.3367892584206579 0.1179682638092182 0.9060928040687974 1.0 1.0 12 Q06787,Q9H6U6 2 +Microtubule based movement 0.2846731867740266 0.1172292859185374 0.9066783601088448 1.0 1.0 72 Q66K74,Q9BW83,Q86UP2,O43805,Q9UL25,Q9Y678,O60313,Q96EV8,Q86Y56,Q9UBK9,Q03001,Q02241,Q9GZT3,A0AVF1,O94901,P33176,P23634,P78318,O95235,Q9Y6G9,Q8TD16,O95817,P23246,P78559,Q00577 25 +Mesenchyme development 0.3042288897228832 0.116625146981661 0.9071571092970344 1.0 1.0 35 O94788,P80723 2 +Antigen receptor mediated signaling pathway 0.3424388642182054 0.1163977592137906 0.9073373112124492 1.0 1.0 21 Q9UJZ1,O95999,O14920,Q96IZ0,P41240,P04439 6 +Negative regulation of protein localization to nucleus 0.3254283239240625 0.1153498480733604 0.9081678289650716 1.0 1.0 8 P61960,Q9ULC3,P21359 3 +Bleb assembly 0.3900034002040153 0.1148998316909413 0.9085245185031294 1.0 1.0 3 Q4KMQ2,Q13464 2 +Positive regulation of establishment of protein localization 0.3004499812229912 0.1145916516796939 0.9087687971124052 1.0 1.0 85 O95486,Q9H6U6,O75312,P55786,P12270,P78371,P50402,O00330,Q9H270,Q05D32,Q9Y282,Q9C0E2,Q12965,Q9Y5K6,O95817,P31751,O00429,P27105,Q8NE86,Q9NV70 20 +Regulation of rho protein signal transduction 0.3250818823975405 0.1145057585295404 0.9088368817790118 1.0 1.0 8 P05556,Q13618,P16949,P52565 4 +Nuclear migration 0.332926544441301 0.1134355653872624 0.9096852445686968 1.0 1.0 11 Q9UH99,Q9Y266 2 +Positive regulation of smooth muscle cell apoptotic process 0.3333218906589155 0.1133271437942035 0.909771198223058 1.0 1.0 5 P98175,P42771 2 +Regulation of ras protein signal transduction 0.339499980494663 0.1125667040342145 0.9103740835557428 1.0 1.0 23 P35241,Q96RT1,Q92538,O95630,P16949,Q9UQ13,P21359,O15294,O95140,P52565 10 +Chromosome organization involved in meiotic cell cycle 0.340569765609731 0.112399238812034 0.9105068588440504 1.0 1.0 16 Q92791,Q96KQ7,Q92878,O94901,O60216,P46379 6 +Negative regulation of blood vessel endothelial cell migration 0.3171587870834154 0.1122440497685671 0.9106299031596012 1.0 1.0 6 P23634 1 +Amine transport 0.3206718803476899 0.1119488449482117 0.9108639673179432 1.0 1.0 7 O75915,Q96EV8,P20337,Q15042 4 +Regulation of lipid localization 0.3415951925517189 0.1115245498889836 0.9112003990334436 1.0 1.0 19 O95486,Q9BZF1,O15260,P31751,Q8WTV0 5 +Cell cycle dna replication 0.3415208664819644 0.1112878631836314 0.9113880793969806 1.0 1.0 19 O75312,P51530,Q14566,O95785 4 +Vascular associated smooth muscle cell proliferation 0.3267647425123272 0.1111401088132615 0.9115052435075524 1.0 1.0 9 P09601,P61586,O95140,P09493 4 +Dna packaging 0.2886304089501022 0.1096009974616743 0.9127258195653204 1.0 1.0 76 P49321,P24941,Q9NRG0,Q9UPP1,Q9H7B4,Q7Z5K2,Q13547,P55209,O95831,Q9NRF9,Q01105,Q99733 12 +Cellular senescence 0.3407767958702104 0.1094406463036795 0.912852996256525 1.0 1.0 18 P24941,Q96MF7,Q96IZ0,P17096,O60313,P67809 6 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.3355089983034933 0.1093639620810296 0.9129138163488444 1.0 1.0 13 Q13526,Q05D32,Q9Y2U8,P62942,Q8N0X7 5 +Positive regulation of deoxyribonuclease activity 0.5645819170632297 0.1093419330630345 0.9129312881845772 1.0 1.0 2 P23396 1 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.3286975576486629 0.1089920500868462 0.91320879588196 1.0 1.0 10 P07602,Q9Y4G8 2 +Negative regulation of dna replication 0.3258822070994316 0.1089717715962993 0.9132248799764566 1.0 1.0 9 Q9UNS1,Q29RF7 2 +Mitotic cytokinetic process 0.3345611019940301 0.1068013969008736 0.914946539249069 1.0 1.0 13 Q8WUX9,O95235,Q9NZZ3,Q9Y3E7,P61586,Q9UN37,O43633,O75351 8 +Nephric duct development 0.5622025832766899 0.106741348615525 0.9149941785265704 1.0 1.0 2 Q15375 1 +Mesenchyme morphogenesis 0.56220258327669 0.106741348615525 0.9149941785265704 1.0 1.0 2 Q06330 1 +Nephric duct morphogenesis 0.5622025832766899 0.106741348615525 0.9149941785265704 1.0 1.0 2 Q15375 1 +Regulation of lipid storage 0.32121203359485 0.1052448430471852 0.916181528672569 1.0 1.0 8 Q9BZF1,Q8WTV0 2 +Regulation of double strand break repair via homologous recombination 0.3389789358271639 0.1048047570448788 0.916530735265072 1.0 1.0 21 Q9UBU8,P35637,Q9UNS1,P15927 4 +External encapsulating structure organization 0.3372947819637017 0.1047991575810815 0.9165351785225112 1.0 1.0 23 P13674,Q92791,Q12965,Q96AY3 4 +Regulation of cell cycle checkpoint 0.3293372371939264 0.1041952158764166 0.9170144304860992 1.0 1.0 11 Q9Y6G9,Q13257,P15927 3 +Positive regulation of mitotic cell cycle phase transition 0.3102875659089862 0.1022081956183728 0.9185914226632376 1.0 1.0 33 Q15398,Q96MF7,Q13042,Q96DY7,P35241,O60885,Q9UJX3,Q13620,P54652,Q9UJX5,O75179,O75351,P31350 13 +Positive regulation of small molecule metabolic process 0.3340882515072345 0.100957922432014 0.919583862486708 1.0 1.0 14 P00403 1 +Copii coated vesicle cargo loading 0.3193059285080742 0.1007969505941982 0.9197116475867396 1.0 1.0 8 Q5JRA6 1 +Golgi to plasma membrane protein transport 0.3373729093118578 0.1006859768060678 0.9197997436860316 1.0 1.0 17 Q01082,P61026,Q9HD26,Q4J6C6 4 +Ribonucleoprotein complex disassembly 0.3249747172066711 0.1006490958846296 0.9198290216764652 1.0 1.0 4 P33176 1 +Regulation of neurotrophin trk receptor signaling pathway 0.5537049626104766 0.0978909153051745 0.922018913875658 1.0 1.0 2 Q7L576 1 +Positive regulation of neurotrophin trk receptor signaling pathway 0.5537049626104766 0.0978909153051745 0.922018913875658 1.0 1.0 2 Q7L576 1 +Production of molecular mediator of immune response 0.3168769858068188 0.0974600360648904 0.9223610696987272 1.0 1.0 31 P04439,O60934,Q9UQ84 3 +Negative regulation of cell cycle g1 s phase transition 0.3303354394794056 0.0956218657751186 0.9238208983977728 1.0 1.0 13 P24941,Q8N6R0,P15927,P25054,O00213 5 +Lipid homeostasis 0.3352519792664009 0.0946209516181248 0.9246159075153052 1.0 1.0 22 P35610,P34913,P09455,O15260,Q8WTV0 5 +Positive regulation of stress fiber assembly 0.3316338314084658 0.0943640233642429 0.9248199934406184 1.0 1.0 14 O60504,P09493,Q08722,P61586,O95429 5 +Regulation of cilium assembly 0.3295545346512583 0.0935997499547073 0.9254271082507716 1.0 1.0 13 Q66K14,Q16181,Q9NT62 3 +Ribonucleoside triphosphate metabolic process 0.2895058712532571 0.0926317179068135 0.9261961448277782 1.0 1.0 37 Q9UJZ1,P00846,Q9ULC3,Q9UIJ7,P00403,P61586,P17812,P06576 8 +Histone h3 deacetylation 0.3187662476051648 0.0923899953793163 0.926388187961843 1.0 1.0 4 Q13547 1 +Neutrophil activation involved in immune response 0.5475866757308032 0.0919340868354682 0.9267504087527454 1.0 1.0 2 P51809 1 +Neutrophil degranulation 0.5475866757308032 0.0919340868354682 0.9267504087527454 1.0 1.0 2 P51809 1 +Peptidyl lysine modification 0.2885657745709464 0.0915281779286535 0.9270729174509986 1.0 1.0 78 Q92791,Q9H7B4,Q96AY3,Q03164,Q9NRF9,Q9UBU8 6 +Positive regulation of peptidase activity 0.2720428410298479 0.0914037920454066 0.927171748748276 1.0 1.0 40 O95999,Q9P0J0,O95831,Q9NR28,P61586,Q92542,O75116,Q96HY6,Q9BXK5 9 +Cell substrate junction organization 0.3266380098436005 0.0905526914895127 0.9278480241423832 1.0 1.0 27 Q05397,Q03001 2 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.331877555436348 0.0902253012179694 0.928108178856362 1.0 1.0 24 Q9NPI6,O75175,Q9UIV1,P67809 4 +Respiratory electron transport chain 0.2538161965547462 0.0898968174842913 0.9283692101934083 1.0 1.0 51 P00403,O96000,P03886 3 +Chondrocyte differentiation involved in endochondral bone morphogenesis 0.545207341944261 0.089709617065839 0.9285179734464232 1.0 1.0 2 P50454 1 +Presynaptic active zone organization 0.3156462585034028 0.0884560914251561 0.9295141814528788 1.0 1.0 4 P20810,P56545,Q8IUD2 3 +Histone phosphorylation 0.3331002831111185 0.0883601771788617 0.9295904114594628 1.0 1.0 17 Q86Y07,Q06787 2 +Golgi to plasma membrane transport 0.3296682241261672 0.0876009195591232 0.9301938712883936 1.0 1.0 25 Q9NV70,P61026,Q01082,Q9HD26,Q4J6C6,Q15334 6 +Positive regulation of stem cell differentiation 0.3146258503401385 0.0872005754412413 0.9305120819646484 1.0 1.0 4 Q9Y6C9,Q13610,Q9H2U1 3 +Establishment of mitochondrion localization 0.3163865607063699 0.086675502641045 0.930929449179172 1.0 1.0 9 Q9UBK9,Q66K74,O60313 3 +Aerobic respiration 0.2976975075319318 0.0865648420090467 0.9310174129705636 1.0 1.0 86 P00846,O75874,O96000,P48735,P03886 5 +Regulation of nucleobase containing compound transport 0.3161980189234676 0.0862520417350257 0.931266061486981 1.0 1.0 9 P12270,Q08J23 2 +Calcium ion transport 0.2583752133615935 0.085142512335634 0.9321480930355224 1.0 1.0 55 Q9UJZ1,P20020,Q9UKS6,P62942,Q96AQ8,Q9HC07,P05026,Q8NE86,Q06787,P23634 10 +Apoptotic process involved in morphogenesis 0.3646051399250793 0.0842343359108656 0.9328701190784496 1.0 1.0 3 P30154 1 +Mitochondrial transport 0.3058056969474031 0.0840921964931181 0.9329831289653852 1.0 1.0 93 Q9H300,P00846,O43772,P55786,O95831 5 +Pigment accumulation 0.3638218293097588 0.0834142919548346 0.9335221247792628 1.0 1.0 3 Q9BXS5,O43747 2 +Pigment granule maturation 0.3638218293097588 0.0834142919548346 0.9335221247792628 1.0 1.0 3 Q9BXS5,O43747 2 +Energy reserve metabolic process 0.3317944315008059 0.082710682293045 0.9340815907377662 1.0 1.0 18 P11310,P22413,P31751,Q06210 4 +Dna modification 0.3195286297314065 0.0823870382177184 0.9343389430124356 1.0 1.0 29 Q96TA1,Q03164 2 +Superoxide metabolic process 0.3143336744395041 0.0811361064059798 0.935333711572562 1.0 1.0 5 P08754,Q04656 2 +Stress granule disassembly 0.3614586262133439 0.080984312573209 0.9354544282757392 1.0 1.0 3 P33176 1 +Regulation of regulated secretory pathway 0.331156078007323 0.0808877757269436 0.9355312016650992 1.0 1.0 18 Q96EV8,Q06787,Q15042,Q4J6C6 4 +Cytokine mediated signaling pathway 0.2817463786756694 0.0799750050997523 0.9362571353211604 1.0 1.0 38 Q9UIV1 1 +Protein o linked glycosylation via serine 0.3135397871349446 0.0799224298529347 0.9362989504481884 1.0 1.0 5 Q10471,Q10472 2 +Positive regulation of protein secretion 0.3309956422223349 0.0792701704692487 0.936817732136092 1.0 1.0 21 O00330,Q9NV70,O95486,Q9Y5K6,Q8NE86,O00429 6 +Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process 0.3596812723421199 0.0792000253844833 0.9368735244035288 1.0 1.0 3 O75116 1 +Regulation of aspartic type peptidase activity 0.3596812723421199 0.0792000253844833 0.9368735244035288 1.0 1.0 3 O75116 1 +Regulation of cell adhesion 0.2978392407621535 0.0791481712242312 0.9369147685643155 1.0 1.0 87 P35241,Q9H6U6,Q14155,Q92990,Q7Z460,O43290,P10644,P46939,P52565,Q13951,Q07021,Q08722,Q13043,P61586,Q96IZ0,P21359,Q5JRA6,P30825,P42771,O95999,P09493,Q9NUQ9,Q15404,P41240,O95429,O75116,P06576,P04439,Q05397 29 +Regulation of torc2 signaling 0.5329707681849164 0.0790618000030483 0.9369834675462309 1.0 1.0 2 Q9NWS0 1 +Spliceosomal complex assembly 0.3088652331048516 0.0781625582167988 0.9376987450789652 1.0 1.0 32 P52756,Q09161,Q12874,Q53GS9,Q07955,Q15637,Q13247,Q9NQ29,Q13242,Q13243,Q15459 11 +Negative regulation of calcium ion transmembrane transport 0.3121610132866287 0.0773655404915963 0.9383327532965268 1.0 1.0 9 Q06787 1 +Blood vessel morphogenesis 0.2815202817366649 0.077278829797337 0.9384017319102784 1.0 1.0 74 P42785,Q9H6U6,Q4VCS5,Q96TA1,P09601,Q9NWT6,O14964,Q9NZ08,Q92990,P19338,Q9Y4G8,P23634,Q12965,Q13685,Q96AY3,P61586,Q5JRA6,P42224,Q9H2J4,Q96PU8,Q86UE4,O75116,P06576,Q05397 24 +Dna unwinding involved in dna replication 0.3278459755522277 0.07672431650649 0.938842859780714 1.0 1.0 16 Q14566,P33991,P17096,Q9BRT9 4 +Chromatin disassembly 0.3227415107052586 0.0765424989680858 0.9389875038390384 1.0 1.0 13 P51532,Q66K74,Q8TAQ2,Q969G3,Q01105,P17096,Q96GM5 7 +Cellular glucan metabolic process 0.3277262472628908 0.0764070545287188 0.9390952573125806 1.0 1.0 16 P11310,P22413,P31751 3 +Regulation of neuron projection development 0.2687278876172275 0.0763441581833823 0.9391452951811337 1.0 1.0 64 Q13308,Q96EV8,P53990,Q9UQB8,P08670,P10586,O14976,Q9UL15,Q32P28,Q9UL25,Q9NQX7,Q9Y4G8,Q8N0X7 13 +Activated t cell proliferation 0.3106498809118708 0.0755929097628047 0.9397429775148908 1.0 1.0 5 P23396,Q14160,P10644,P09429 4 +Heme transport 0.5282121006118372 0.0752692093539135 0.9400005193426344 1.0 1.0 2 O15173 1 +Iron coordination entity transport 0.5282121006118372 0.0752692093539135 0.9400005193426344 1.0 1.0 2 O15173 1 +Regulation of reactive oxygen species metabolic process 0.3224840706536593 0.0750550905317308 0.9401708795523108 1.0 1.0 27 P00403,P42785 2 +Pyrimidine nucleoside triphosphate metabolic process 0.3142727850279762 0.0749888957727437 0.9402235469059406 1.0 1.0 10 Q9H773 1 +Tube formation 0.3291296248316838 0.0748513169247774 0.9403330112999936 1.0 1.0 22 Q13308,O95999,Q92990,Q9H6U6,Q13043,O60313,O14641,P11233 8 +Nls bearing protein import into nucleus 0.3108170704934927 0.0744837690099382 0.9406254557433652 1.0 1.0 9 Q8NFH5,P52292 2 +Post embryonic development 0.3238633426154192 0.0744023956917326 0.9406902026026356 1.0 1.0 14 P11310,Q12965 2 +N terminal protein amino acid modification 0.3072105033774258 0.0743313361308672 0.9407467433653828 1.0 1.0 8 Q9BV86 1 +Regulation of exocytosis 0.2563507322025062 0.0742717825255519 0.9407941292846632 1.0 1.0 42 O14964,Q96EV8,P61026,Q92783,Q9Y3E7,Q9UL25,Q7Z460,Q15042,P11233,Q06787,P09601,Q4J6C6 12 +Regulation of microtubule cytoskeleton organization 0.2579480538355358 0.0731454044374956 0.9416904108839732 1.0 1.0 56 P46821,Q66K74,Q14203,O43633,P12270,O75351,P23396,Q13464,Q14155,Q9ULW0,Q7Z460,Q14008,P25054,P53350,Q8WUX9,Q16625,Q9NZZ3,Q9Y3E7,Q9Y6A5,Q9HD47,Q8TD16,P16949,P61586,Q00610,O15344,P37198,P54646,P04350,P0DMV9,P78559 30 +Nervous system process involved in regulation of systemic arterial blood pressure 0.5234534330387577 0.0716649216056077 0.942868572858088 1.0 1.0 2 P04179 1 +Tricarboxylic acid cycle 0.3277670076535131 0.0705935157201198 0.94372127124465 1.0 1.0 22 O75874,P48735 2 +Regulation of atp dependent activity 0.3164030764991731 0.0701525155608584 0.9440722682512452 1.0 1.0 29 Q8NFQ8,Q8IXB1,P05026 3 +Genomic imprinting 0.5207341944255696 0.0696880890370945 0.9444419223042256 1.0 1.0 2 Q13263 1 +Regulation of genetic imprinting 0.5207341944255696 0.0696880890370945 0.9444419223042256 1.0 1.0 2 Q13263 1 +Methylation 0.2962430554177866 0.0682851570163055 0.945558639533234 1.0 1.0 87 Q8NB78,Q8N2A8,Q8N6R0,Q9H7B4,O60725,Q5VTR2,Q96FX7,Q96TA1,Q03164,Q9BV86,Q08J23 11 +Nuclear pore complex assembly 0.3038147138964597 0.0674491320404335 0.946224156499682 1.0 1.0 8 Q92621,Q8N1F7,P52948,P49790,P57740,P12270,Q9BTX1 7 +Positive regulation of actin filament bundle assembly 0.322764705498989 0.0673400520594915 0.946310992302771 1.0 1.0 15 O60504,P09493,Q08722,P61586,O95429 5 +Gas homeostasis 0.5166553365057858 0.0668333275304618 0.946714391181278 1.0 1.0 2 P04179 1 +Receptor signaling pathway via stat 0.3235460705239977 0.0655480692002435 0.947737634910304 1.0 1.0 16 O14964,P42224,Q9UIV1,Q9NX40,O95630 5 +Scarna localization to cajal body 0.294557823129257 0.0655216625543173 0.9477586591691908 1.0 1.0 4 O60832,P78371,P17987 3 +Metanephros development 0.3095202880209592 0.0647657230341309 0.9483605331845026 1.0 1.0 10 P80723 1 +White fat cell differentiation 0.5129163834126531 0.0643306003086758 0.948706988387396 1.0 1.0 2 P56545 1 +Negative regulation of histone h4 acetylation 0.5129163834126516 0.0643306003086747 0.9487069883873968 1.0 1.0 2 Q9NWS0 1 +Changes to dna methylation involved in embryo development 0.5118966689327078 0.0636666552540466 0.949235656111586 1.0 1.0 2 Q13263 1 +Cell differentiation involved in phenotypic switching 0.5118966689327064 0.0636666552540458 0.9492356561115868 1.0 1.0 2 P04179 1 +Reversible differentiation 0.5118966689327064 0.0636666552540458 0.9492356561115868 1.0 1.0 2 P04179 1 +Positive regulation of synaptic plasticity 0.341040462427741 0.0626456698927208 0.9500486614973942 1.0 1.0 3 P46821,Q9UJX6 2 +Platelet derived growth factor receptor beta signaling pathway 0.5101971447994651 0.0625775768901469 0.9501028854637896 1.0 1.0 2 P18031 1 +Skin epidermis development 0.3165534253612541 0.0619646621677265 0.9505909734048557 1.0 1.0 13 Q08J23,P18074 2 +Hepaticobiliary system development 0.3013245137448871 0.0616925496558499 0.9508076731827076 1.0 1.0 33 O00330,P35610,O94788 3 +Semi lunar valve development 0.2901329962009341 0.0614816661160941 0.9509756151012044 1.0 1.0 4 Q13464,O75116 2 +Midbody abscission 0.3110379568322022 0.0614423521524635 0.951006923914174 1.0 1.0 11 Q8WUX9,O95235,Q9NZZ3,Q9Y3E7,Q9UN37,O75351 6 +Smooth muscle cell migration 0.2999583746122412 0.0599246805143546 0.9522156230060412 1.0 1.0 8 Q13685,P09493 2 +Endosome to lysosome transport 0.3210457071855029 0.059255872357769 0.952748308075674 1.0 1.0 16 Q6P3W7,Q9H270,Q9H267,Q9Y3E7,Q99816,O95295,P51809,Q8TDB6,O75351,Q96L92 10 +Regulation of dna recombination 0.2539204762607522 0.0590829344098357 0.952886051262262 1.0 1.0 42 P15927,P52292,Q7Z4V5,Q9UBU8,Q9UNS1,P18074,P35637 7 +Anatomical structure maturation 0.3105852805937928 0.0583858430259087 0.953441291163872 1.0 1.0 30 Q8N2A8,Q12768,O94788,O75179,Q08J23 5 +Nucleic acid phosphodiester bond hydrolysis 0.2885617646789569 0.0577783900971422 0.9539251516215674 1.0 1.0 82 Q8N2A8,P22413,Q9UIV1,Q5TA45,Q9BQ61,Q9UQ84,O95831,Q09161,Q6UN15,O15091,Q9UPY3,P51530,P18074,Q9NPI6,Q15631 15 +Positive regulation of calcineurin mediated signaling 0.5006798096533062 0.0568724802064554 0.9546467764338208 1.0 1.0 2 P26599 1 +Centrosome separation 0.2846392712638941 0.0568166191231446 0.9546912751771712 1.0 1.0 4 P43487,Q9UNZ2 2 +Negative regulation of protein secretion 0.3016716188830647 0.0558896542952185 0.9554297126249602 1.0 1.0 9 Q16850 1 +Negative regulation of ion transport 0.3230446500237331 0.0557793326967547 0.9555175994250896 1.0 1.0 20 Q06787,Q9HD26,Q9UKS6 3 +Nuclear envelope organization 0.309834464907606 0.0554840554904382 0.9557528322571986 1.0 1.0 30 Q8NC56,P02545,Q8WUX9,Q9UNZ2,Q8N1F7,Q9UH99,Q9Y2U8,Q9NZZ3,Q9Y3E7,P20700,Q14203,O94901,Q9UN37,O43633,P50402 15 +Positive regulation of protein localization to membrane 0.3201988041653645 0.0553286478265664 0.9558766394511756 1.0 1.0 25 P27105,O00264,Q01082,Q12965,P31751,Q15334 6 +Intrinsic apoptotic signaling pathway 0.2844846837146713 0.0552799417561414 0.9559154418874972 1.0 1.0 79 O00330,Q86TM6,Q13547,Q8IXB1,Q9H300,O60934,O95831,Q9NYF8,Q9NR28,P10909,Q9UL15,Q8N2F6,P61978 13 +Mrna alternative polyadenylation 0.2823129251700736 0.0549551117281565 0.9561742253673132 1.0 1.0 4 O43809,Q8N684,Q96MU7 3 +Positive regulation of cell cycle process 0.273171767798506 0.0548536705154053 0.9562550418426008 1.0 1.0 70 Q96MF7,P35241,Q13257,P12270,Q96DY7,Q9UJX3,Q02241,O60216,O75179,Q96HY6,Q15398,Q13042,Q9UNZ2,Q9Y6G9,P61586,O60885,O94966,P31350,P23246,Q8WWQ0,O95785,Q6ZWJ1,O75116 23 +Dendrite arborization 0.4959211420802268 0.0542616680203722 0.9567266890256892 1.0 1.0 2 Q13641 1 +Cardiac ventricle development 0.3168569338008007 0.0530634284044425 0.9576813702852376 1.0 1.0 15 Q13308,P09493 2 +Innate immune response 0.321100351289506 0.0525164476144125 0.958117190117494 1.0 1.0 110 Q96S55,P01889,P19474,Q9NZ08,Q9UIV1,Q9BWS9,O14920,Q9Y5A7,P10909,O75179,Q8WXF1,Q07021,Q12965,Q08722,O95999,P08670,Q9Y4E8,P04439,Q96PK6,Q05397 20 +Nephron morphogenesis 0.2789115646258551 0.0523521070955765 0.9582481347497204 1.0 1.0 4 P42224,O95747,Q13418 3 +Adherens junction assembly 0.278911564625855 0.0523521070955765 0.9582481347497204 1.0 1.0 4 P18206,Q9BTW9,Q13177 3 +Substantia nigra development 0.3195409756018602 0.0522234684108991 0.9583506333580116 1.0 1.0 17 P80723 1 +Protein deneddylation 0.2912176143120173 0.0515838859519482 0.9588602593920004 1.0 1.0 7 Q99627,Q9BT78 2 +Regulation of adenylate cyclase activity 0.3251328478373852 0.0514287191240544 0.9589839004956896 1.0 1.0 3 P21359 1 +Positive regulation of dna templated transcription initiation 0.2945861872774263 0.0499567961734035 0.9601568169639764 1.0 1.0 8 Q9NYF8 1 +Phagolysosome assembly 0.4870836165873651 0.0498174928882215 0.9602678266819692 1.0 1.0 2 P51149 1 +Phagosome maturation 0.4870836165873651 0.0498174928882215 0.9602678266819692 1.0 1.0 2 P51149 1 +Hormone mediated signaling pathway 0.2705355005159839 0.0495918820672251 0.9604476158455892 1.0 1.0 39 Q9GZZ9,Q96HY6,P42785 3 +Germ cell proliferation 0.4857239972807678 0.0491786915145941 0.9607768924235344 1.0 1.0 2 P20042 1 +Regionalization 0.3201266359594815 0.0490501766234709 0.9608793088705097 1.0 1.0 23 Q8N2A8,P80723,O94788,O14641 4 +Regulation of synaptic transmission gabaergic 0.3201229987297206 0.0484032750916728 0.9613948492205568 1.0 1.0 3 P33176 1 +Dephosphorylation of rna polymerase ii c terminal domain 0.319619177150627 0.048111722388714 0.9616272039103146 1.0 1.0 3 Q9NP77,Q9NQG5 2 +Regulation of response to wounding 0.3196751091895238 0.0478468646517401 0.961838286711328 1.0 1.0 19 P10586 1 +Regulation of iron ion transport 0.4802855200543945 0.0467383345234143 0.9627217771851044 1.0 1.0 2 Q04656 1 +Regulation of iron ion transmembrane transport 0.4802855200543945 0.0467383345234143 0.9627217771851044 1.0 1.0 2 Q04656 1 +Peripheral nervous system development 0.3068908945624504 0.0466499752528753 0.9627922008670552 1.0 1.0 12 P31751 1 +Insulin secretion 0.3192878660803813 0.0465456889475865 0.9628753190112852 1.0 1.0 23 O00330,Q16836,Q8NE86,O43768 4 +Mesoderm morphogenesis 0.3167663240103013 0.0465035933671377 0.9629088700939769 1.0 1.0 3 P10644 1 +Import into cell 0.3190033959020848 0.0457009958079493 0.9635485701003932 1.0 1.0 23 P30825,P05026,P08195,P20337,P31751,Q15043,P23634 7 +Negative regulation of activated t cell proliferation 0.3151984358990358 0.0456502997663422 0.9635889775170036 1.0 1.0 3 P10644 1 +Regulation of neurotransmitter transport 0.3162200072826676 0.0440715343288858 0.9648473830450686 1.0 1.0 17 Q06787,Q15042,Q4J6C6 3 +Negative regulation of nuclease activity 0.4738273283480685 0.0440703347880844 0.9648483392111477 1.0 1.0 2 P61221 1 +Diadenosine polyphosphate metabolic process 0.3107786467188004 0.0433583430783232 0.9654158838598051 1.0 1.0 3 Q9BW91,Q15046 2 +Regulation of histone h4 k16 acetylation 0.4717878993881798 0.0432775934346922 0.9654802523333974 1.0 1.0 2 Q9NWS0 1 +Calcium ion import into sarcoplasmic reticulum 0.4717878993881772 0.0432775934346911 0.9654802523333984 1.0 1.0 2 P16615 1 +Positive regulation of striated muscle contraction 0.47144799456153 0.0431477316645445 0.9655837703382744 1.0 1.0 2 P78417 1 +Developmental growth involved in morphogenesis 0.2797683299265828 0.0431243661964668 0.9656023959479354 1.0 1.0 37 Q13308,P53990,O60271,Q9UL25,Q8N0X7,Q9Y263 6 +Embryonic digit morphogenesis 0.2861563084219897 0.0429926904517324 0.965707360642294 1.0 1.0 7 Q13547 1 +Regulation of mrna metabolic process 0.3472475557005705 0.0412988316987077 0.9670576644467136 1.0 1.0 135 Q9Y5S9,A2RRP1,P52756,Q99729,Q09161,Q92804,Q96E39,P31483,O75175,Q13242,P49137,P61978,P98175,Q9UIV1,Q08170,P51114,P62995,P84103,Q15637,O00267,P19338,Q6PJT7,Q06787,P67809,P38159,Q07021,O75150,Q5VTR2,Q9Y2W1,P98179,P35637,Q9NPI6,Q9H074,Q8N684,P08670,Q96PU8,Q13247,Q9BWF3,O75116,P11940,Q14011,P22626,O60506,Q9P2K5 44 +Fibroblast proliferation 0.3095390148705169 0.04128434398358 0.9670692141206678 1.0 1.0 14 P50402,Q96IZ0 2 +Pore complex assembly 0.3042291950886745 0.0412679613412525 0.9670822744477304 1.0 1.0 12 P55196,P49368,Q92621,Q8N1F7,P52948,P49790,Q4KMQ2,P57740,P50990,P12270,Q9BTX1 11 +Nuclear pore organization 0.3042291950886704 0.0412679613412444 0.967082274447737 1.0 1.0 12 Q8NFH5,Q92621,Q8N1F7,Q96EE3,P52948,P49790,P57740,Q8WUM0,P12270,Q7Z3B4,Q9BTX1 11 +Maintenance of presynaptic active zone structure 0.4660095173351518 0.0411557190197835 0.9671717548433212 1.0 1.0 2 P56545 1 +Histone h4 k5 acetylation 0.2599734774979906 0.0402690173349046 0.9678786543199068 1.0 1.0 4 O95251 1 +Indolalkylamine metabolic process 0.4632902787219672 0.0402186442145564 0.967918813721338 1.0 1.0 2 Q04656 1 +Positive regulation of dna demethylation 0.4622705642420223 0.0398770708615414 0.9681911313614628 1.0 1.0 2 Q93009 1 +Regulation of skeletal muscle cell differentiation 0.2574829931972868 0.038961665714164 0.968920951720604 1.0 1.0 4 Q9BYT8,P17844,Q92841 3 +Response to lithium ion 0.4592114208021823 0.0388837987382582 0.96898303353432 1.0 1.0 2 P27797 1 +Cell junction disassembly 0.4588715159755347 0.0387763036993475 0.969068737530747 1.0 1.0 2 Q00535 1 +Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity 0.4588715159755335 0.0387763036993472 0.9690687375307472 1.0 1.0 2 P18031 1 +B cell proliferation 0.2962184306200467 0.0387359888051457 0.9691008800137024 1.0 1.0 10 Q96IZ0 1 +Negative regulation of neuron differentiation 0.283343553392672 0.0384402894803303 0.969336638346074 1.0 1.0 7 O60271 1 +Interleukin 6 production 0.3054207458837509 0.0379408853539794 0.9697348147037675 1.0 1.0 13 P01889,Q08722,O95999,P49137 4 +Regulation of hyaluronan biosynthetic process 0.4561522773623442 0.0379365665356179 0.9697382581432152 1.0 1.0 2 Q00610 1 +Hyaluronan biosynthetic process 0.4561522773623442 0.0379365665356179 0.9697382581432152 1.0 1.0 2 Q00610 1 +Hyaluronan metabolic process 0.4561522773623442 0.0379365665356179 0.9697382581432152 1.0 1.0 2 Q00610 1 +Response to alkaloid 0.3147818575744118 0.0376733792242232 0.9699481012258356 1.0 1.0 18 O00330 1 +Positive regulation of sterol transport 0.454452753229103 0.0374296870140822 0.9701424024353276 1.0 1.0 2 P07355 1 +Regulation of intracellular lipid transport 0.454452753229103 0.0374296870140822 0.9701424024353276 1.0 1.0 2 P07355 1 +Positive regulation of intracellular lipid transport 0.454452753229103 0.0374296870140822 0.9701424024353276 1.0 1.0 2 P07355 1 +Protein heterotetramerization 0.2826012938372428 0.0372652129903561 0.9702735422284728 1.0 1.0 7 Q9NSD9,O43809,P23921,Q8N684,Q9Y285,P31350 6 +Cellular response to cadmium ion 0.2508367505108979 0.0357634053388804 0.9714710126977149 1.0 1.0 4 P09601 1 +Mitochondrial transcription 0.2924175450526987 0.0354937439127217 0.9716860348682512 1.0 1.0 3 P52815,O00411 2 +Cd4 positive alpha beta t cell activation 0.2810099841682008 0.0347827682015921 0.9722529613000854 1.0 1.0 7 Q13951 1 +Regulation of neurogenesis 0.2429728101899605 0.0342631239459683 0.9726673304209456 1.0 1.0 49 Q14444,P53990,Q96T58,Q13547,Q9UQB8,Q96G23,P55209,Q9UL25,P21359,Q9UPY3,Q9Y4G8,Q8N0X7,Q13573,P35221 14 +Late endosome to vacuole transport 0.2936972555661493 0.0342287729364781 0.9726947224938484 1.0 1.0 10 Q9NP79,Q8WUX9,Q9Y3E7,Q92783 4 +Spliceosomal conformational changes to generate catalytic conformation 0.4422161794697591 0.034164265857501 0.9727461616109214 1.0 1.0 2 Q9HCS7 1 +Regulation of mitochondrial dna replication 0.2883302717239753 0.0340732346868299 0.972818751713554 1.0 1.0 3 Q9UJZ1 1 +Chemokine c x c motif ligand 2 production 0.4405166553365123 0.0337610471184994 0.9730676981216564 1.0 1.0 2 P14174 1 +Positive regulation of chemokine c x c motif ligand 2 production 0.4405166553365123 0.0337610471184994 0.9730676981216564 1.0 1.0 2 P14174 1 +Positive regulation of activated t cell proliferation 0.4405166553365123 0.0337610471184994 0.9730676981216564 1.0 1.0 2 P23396 1 +Myeloid dendritic cell activation 0.4405166553365114 0.0337610471184991 0.9730676981216566 1.0 1.0 2 Q06330 1 +Ether metabolic process 0.2848495331760741 0.0334019368404994 0.973354065150602 1.0 1.0 8 P34913 1 +Mammary gland development 0.3150122725509058 0.0333814925928384 0.9733703682086248 1.0 1.0 21 P00403 1 +Regulation of dna templated transcription in response to stress 0.2966613392459369 0.0330003278853033 0.973674326170336 1.0 1.0 11 Q9NWT6,P09601,Q9NYF8 3 +Endosomal vesicle fusion 0.2840087044524424 0.0326889318882541 0.9739226502492973 1.0 1.0 3 Q9H270 1 +Regulation of microtubule polymerization or depolymerization 0.2943819274512119 0.0325964276472075 0.973996418642785 1.0 1.0 33 P46821,Q66K74,P04350,Q7Z460,P16949,Q14203,O15344,P25054,P78559,Q14155 10 +Positive regulation of cell adhesion molecule production 0.4350781781101346 0.0325471625124304 0.9740357056874354 1.0 1.0 2 O75955 1 +Vitamin catabolic process 0.4347382732834885 0.0324750453491551 0.9740932164569034 1.0 1.0 2 P49914 1 +Endothelial cell morphogenesis 0.4323589394969466 0.031982169559297 0.974486270253857 1.0 1.0 2 Q9Y696 1 +Positive regulation of megakaryocyte differentiation 0.4316791298436501 0.0318451327740363 0.9745955541230412 1.0 1.0 2 P26583 1 +Negative chemotaxis 0.2798559125745061 0.0314666942241588 0.9748973531435864 1.0 1.0 3 P61586 1 +Neural tube formation 0.3118130032827781 0.0305744922399962 0.9756088848805224 1.0 1.0 18 Q13308,O95999,Q92990,Q13043,O60313,O14641,P11233 7 +Cap dependent translational initiation 0.4242012236573814 0.0304438775850846 0.975713051805907 1.0 1.0 2 Q04637 1 +Pyrimidine ribonucleoside triphosphate metabolic process 0.2780110658395239 0.0302399839177208 0.9758756605461634 1.0 1.0 7 P17812 1 +Regulation of nitric oxide metabolic process 0.3015051005794046 0.0301626242652545 0.9759373564750556 1.0 1.0 13 P10909 1 +Protein heterooligomerization 0.2826975476839284 0.0300024467057172 0.976065101861417 1.0 1.0 8 Q9NSD9,O43809,P23921,Q8N684,Q9Y285,P31153,P31350 7 +T helper 17 type immune response 0.4170632222977614 0.0292760648394084 0.9766444162095462 1.0 1.0 2 P40763 1 +Response to platelet derived growth factor 0.2820686079165166 0.0290264395365998 0.9768435037742936 1.0 1.0 8 Q13547 1 +3 utr mediated mrna stabilization 0.2818786038526032 0.0287331400649783 0.9770774253229824 1.0 1.0 8 P49137 1 +Golgi localization 0.2309523809523867 0.0284436832179776 0.9773082841120084 1.0 1.0 4 Q9Y678,P48444,P63104 3 +Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.2672560353621148 0.0283476003584311 0.9773849162412196 1.0 1.0 3 Q9UNN5,Q13043 2 +Regulation of wound healing spreading of epidermal cells 0.2302721088435435 0.0282460485549918 0.9774659104243416 1.0 1.0 4 Q7Z460,Q96AC1,O75122 3 +Wound healing spreading of epidermal cells 0.2302721088435435 0.0282460485549918 0.9774659104243416 1.0 1.0 4 Q7Z460,Q96AC1,O75122 3 +Aortic valve morphogenesis 0.2638558313498738 0.027643664806533 0.977946355479647 1.0 1.0 3 Q13464,O75116 2 +Ventricular septum morphogenesis 0.2638558313498742 0.027643664806533 0.977946355479647 1.0 1.0 3 O96028,Q06330 2 +Regulation of glycogen starch synthase activity 0.3990482664853879 0.0269626217342541 0.9784895467199152 1.0 1.0 2 P49840 1 +Regulation of type b pancreatic cell development 0.3990482664853879 0.0269626217342541 0.9784895467199152 1.0 1.0 2 P49840 1 +Response to interleukin 3 0.3990482664853879 0.0269626217342541 0.9784895467199152 1.0 1.0 2 P49840 1 +Gtp metabolic process 0.2931693520236708 0.026770319482949 0.978642926351748 1.0 1.0 11 P61586,Q9ULC3,Q9UIJ7 3 +Forebrain generation of neurons 0.2699767129031003 0.0263639740790393 0.9789670286756036 1.0 1.0 6 Q9Y4G8 1 +Regulation of glial cell differentiation 0.2890925402417832 0.0263431195978465 0.9789836623670398 1.0 1.0 10 Q9UPY3 1 +Glomerular visceral epithelial cell migration 0.3898708361658804 0.0260779023336443 0.9791952024512494 1.0 1.0 2 Q13464 1 +N acetylneuraminate metabolic process 0.2533151989119284 0.0257854169057523 0.9794284936059732 1.0 1.0 3 P46926,Q8NFW8 2 +Positive regulation of cell projection organization 0.2546315750615932 0.0255868399145503 0.9795868828616952 1.0 1.0 59 Q13308,P53990,Q9UQB8,Q9H6U6,Q06787,Q16181,O60493,Q9UL25,O14641,P25054,P11233,Q9Y4G8,Q32P28,Q15334 14 +Termination of rna polymerase ii transcription 0.3837525492862067 0.0255798857379469 0.9795924296763244 1.0 1.0 2 Q9NP77 1 +Neurotransmitter transport 0.3094838492359523 0.0255431794507967 0.979621707489618 1.0 1.0 26 Q06787,Q4J6C6,Q96QD8 3 +Regulation of histone h3 k27 methylation 0.2492349540972389 0.0251849623516017 0.9799074314579 1.0 1.0 3 Q7KZ85,O15294 2 +Response to mechanical stimulus 0.3117128353914459 0.0247935036869993 0.9802196727739824 1.0 1.0 21 Q05397,Q96QD8 2 +Trna catabolic process 0.2791800538351396 0.0246450810966724 0.980338060691565 1.0 1.0 8 Q9UPY3 1 +Isotype switching to igg isotypes 0.3480625424881086 0.0237643265605622 0.9810405952887786 1.0 1.0 2 P43246 1 +Response to insecticide 0.327328348062548 0.0232771098320327 0.9814292304743332 1.0 1.0 2 P46821 1 +Mammary gland involution 0.3232494901427655 0.0232116866165959 0.9814814165478132 1.0 1.0 2 P07384 1 +Epithelial cell proliferation involved in lung morphogenesis 0.2308738524311391 0.0231554691692635 0.981526259528398 1.0 1.0 3 Q02750,Q13247 2 +Zymogen inhibition 0.3154316791298496 0.0231074287831232 0.9815645799574796 1.0 1.0 2 P20810 1 +Macrophage apoptotic process 0.2974167233174774 0.0229486299093436 0.9816912495367408 1.0 1.0 2 P42771 1 +Regulation of macrophage apoptotic process 0.2974167233174774 0.0229486299093436 0.9816912495367408 1.0 1.0 2 P42771 1 +Autonomic nervous system development 0.2787219578518084 0.0228628213106622 0.9817596969342108 1.0 1.0 2 P21359 1 +Sympathetic nervous system development 0.2787219578518084 0.0228628213106622 0.9817596969342108 1.0 1.0 2 P21359 1 +Branching involved in blood vessel morphogenesis 0.2787219578518083 0.0228628213106622 0.9817596969342108 1.0 1.0 2 Q13043 1 +Negative regulation of oligodendrocyte differentiation 0.2787219578518084 0.0228628213106622 0.9817596969342108 1.0 1.0 2 P21359 1 +Negative regulation of osteoclast differentiation 0.2787219578518084 0.0228628213106622 0.9817596969342108 1.0 1.0 2 P21359 1 +Negative regulation of glial cell differentiation 0.2787219578518084 0.0228628213106622 0.9817596969342108 1.0 1.0 2 P21359 1 +Negative regulation of myeloid leukocyte differentiation 0.2787219578518084 0.0228628213106622 0.9817596969342108 1.0 1.0 2 P21359 1 +Forebrain morphogenesis 0.2709041468388923 0.0228417209101063 0.9817765282225964 1.0 1.0 2 P21359 1 +Cellular response to fatty acid 0.2626743790404874 0.0227952356748553 0.9818136084193352 1.0 1.0 5 P50416,Q15120,Q96GM5,P13010 4 +Positive regulation of fibroblast proliferation 0.2626743790404859 0.0227952356748542 0.981813608419336 1.0 1.0 5 P14174,Q08211,Q7Z5K2,P14635 4 +Cytoplasmic sequestering of protein 0.2867021651807336 0.0224246530911183 0.9821092149716016 1.0 1.0 10 Q9HD26 1 +Nucleus localization 0.2939392874300025 0.0219405162239633 0.9824954052719964 1.0 1.0 12 Q9UH99,Q9Y266 2 +Regulation of fibroblast migration 0.2815882613684665 0.0212094673723354 0.9830785621111232 1.0 1.0 9 O95429,Q05397,Q14155 3 +Reactive nitrogen species metabolic process 0.3077297334110521 0.0211812233102693 0.9831010925507936 1.0 1.0 18 P10909,Q08722 2 +Regulation of centrosome cycle 0.299158530349665 0.0202723961770897 0.9838260759204642 1.0 1.0 14 P37198,Q9NZZ3,Q9Y3E7,O75116,P06748,O43633,O75351,Q96PK6 8 +Stress activated protein kinase signaling cascade 0.2945304987507993 0.0200651836262678 0.9839913739918728 1.0 1.0 32 Q99956,O14920 2 +Regulation of gene expression epigenetic 0.2698494567138424 0.0193507716504556 0.9845612815772592 1.0 1.0 38 Q8NB78,P24941,Q13547,Q9UPP1,Q92990,Q8NEY8,Q9NRF9,Q13330 8 +Anion transport 0.2638554884009344 0.0192602669572996 0.9846334804189651 1.0 1.0 67 Q6N075,O60831,Q9UHG3,Q9HD26,Q9Y619,P07602,Q08722,Q15042,Q96QD8,Q96S66,Q9BQT8 11 +Endothelium development 0.3090112384399344 0.0186623210254642 0.985110486482204 1.0 1.0 24 P35241,Q9UDY2,O14920,Q9Y4G8,P61586,O75116,P35611 7 +Stress fiber assembly 0.3071902514465351 0.0185916277355663 0.9851668817823312 1.0 1.0 26 O60504,P09493,Q7Z460,Q08722,P16949,P61586,O95429,O75116 8 +Hormone transport 0.2935608332003679 0.0164384988309884 0.9868845662673322 1.0 1.0 32 O00330,Q16836,Q96TA1,Q8NE86,O43768 5 +Dendritic spine morphogenesis 0.3039691009073195 0.0163893795359303 0.9869237525154086 1.0 1.0 17 Q96EV8,Q9UQB8,Q15334 3 +Positive regulation of leukocyte cell cell adhesion 0.3080994582279476 0.0161388418108607 0.9871236262604384 1.0 1.0 24 O95999,Q9NUQ9,Q08722,P61586,P41240,P04439,Q13951,P30825 8 +Toxin transport 0.2901446283573098 0.0153999034958358 0.9877131404172544 1.0 1.0 12 P78371,Q93050 2 +Lipid storage 0.3033121064961255 0.0150107988054006 0.9880235651527371 1.0 1.0 17 P22413,O60664,Q9BZF1,Q14534,P35610,Q8WTV0 6 +T cell proliferation 0.3080775236267273 0.014972760601567 0.988053911837842 1.0 1.0 22 P04439,Q96IZ0,Q92990,P17812 4 +Sterol transport 0.3071238821509562 0.0133557729290247 0.9893439517816844 1.0 1.0 21 P10909,Q9BZF1,P35610,Q8WTV0 4 +Peroxisome organization 0.271045519260388 0.0131864325165573 0.9894790539843804 1.0 1.0 8 O00429 1 +Positive regulation of alpha beta t cell activation 0.2755067147087993 0.0123323531454668 0.990160455238528 1.0 1.0 9 P04439,Q13951 2 +Cardiac chamber morphogenesis 0.2749574962137803 0.011566721732279 0.9907712970944054 1.0 1.0 9 P09493 1 +Regulation of receptor mediated endocytosis 0.3065029893306727 0.0109522458226442 0.9912615468510456 1.0 1.0 23 Q13432,Q96EV8,Q9UL25,P10909,Q06787,P61978,Q15334 7 +Regulation of extent of cell growth 0.3050615595075089 0.0100771408065276 0.9919597410133962 1.0 1.0 20 P46821,Q00535,Q7L576,Q9H2P0,Q9UL25,Q16643,Q8N0X7,P50570,Q9UJX6,Q16555,Q9UPN3,Q14247,P43034,P53990,Q9UJU6,P49841,P31150,Q15375,P78344 19 +Synaptic transmission gabaergic 0.2421372454698166 0.009783627054518 0.992193919556914 1.0 1.0 5 P33176 1 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.2857830219046032 0.0082664360159661 0.9934044134471776 1.0 1.0 12 Q8WUX9,Q92783,Q9NZZ3,Q9Y3E7,Q9UN37,O75351,Q9Y263 7 +Negative regulation of protein containing complex assembly 0.276681855983565 0.0081392664802484 0.99350587664264 1.0 1.0 36 P35241,Q9NUQ9,P04350,Q01082,P16949,Q13813,O15020,P10909,P35611,Q14155 10 +Synaptic vesicle exocytosis 0.299470450446952 0.0071643021985136 0.9942837627866884 1.0 1.0 17 Q06787,Q15042,Q4J6C6 3 +Positive regulation of ubiquitin dependent protein catabolic process 0.3001340722630007 0.006053396160311 0.9951701181606628 1.0 1.0 28 P10909,Q96HY6,Q9Y5A7,Q05397 4 +Telomere maintenance 0.2448972290376609 0.0053334159462286 0.9957445699346896 1.0 1.0 54 P15927,O60934,Q9UQ84,P51530,P78371,P49750 6 +Positive regulation of proteolysis 0.2864374187381911 0.0052936761025961 0.9957762772947584 1.0 1.0 87 Q9BXK5,O95999,O43847,Q96JB5,O75150,P46379,O95831,Q9UKS6,Q9NR28,Q92542,Q9Y5A7,P10909,Q06787,Q96HY6,Q05397 15 +Reactive oxygen species metabolic process 0.2615525255120834 0.0041295829884374 0.9967050788559396 1.0 1.0 39 P00403,P42785 2 +Protein acylation 0.2368518031775158 0.0041145040598347 0.9967171099980524 1.0 1.0 48 Q9NRF9,Q03164,Q9UBU8 3 +Iron ion transmembrane transport 0.2266076896903647 0.0029117811299735 0.9976767380749084 1.0 1.0 5 Q9H1K1,Q04656,O75027,Q15043 4 +Spinal cord development 0.2775371997918176 0.0020482238289715 0.9983657549724648 1.0 1.0 11 Q6Y7W6,O95817,O75312,P21359,P18074 5 +Regulation of hormone levels 0.2533134587299093 0.0015370017242233 0.9987736505371644 1.0 1.0 61 O00330,O94788,P09455,Q8NE86 4 +Barbed end actin filament capping 0.2673221557434583 0.0015278369107439 0.998780962991756 1.0 1.0 9 P35611,P35241 2 +Dna strand elongation involved in dna replication 0.2851925680783971 0.0014580306761619 0.9988366602464952 1.0 1.0 13 Q9NRF9,P33991,P51530 3 +Response to temperature stimulus 0.2311052179234524 0.0012640579043595 0.9989914279827404 1.0 1.0 44 P11310,P00403,Q14011 3 +Response to bmp 0.2980585811521767 0.0006364893299036 0.9994921550248436 1.0 1.0 18 Q9Y4E8,Q8N0X7,Q05D32,Q9Y2U8 4 +Protein insertion into mitochondrial inner membrane 0.2661174120274073 4.528831753340863e-05 0.9999638651506676 1.0 1.0 9 Q9Y5J7,Q9Y5J9,Q9Y5L4 3 +Focal adhesion assembly 0.3014495126603385 2.6840365763701157e-05 0.9999785844865534 1.0 1.0 21 Q9H6U6,Q14247,Q7Z460,P61586,O75116,Q05397 6 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8a76bfb2eda5a8f056ccc7c85a5f6e73703fd2a7 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "Bundle of his cell to purkinje myocyte signaling", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate commitment involved in pattern specification", "Cell fate determination", "Cell fate specification", "Cell fate specification involved in pattern specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system myelin maintenance", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Corticotropin secretion", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Elastic fiber assembly", "Elastin metabolic process", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fructose transmembrane transport", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastric acid secretion", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune complex clearance", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal epithelial structure maintenance", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learning", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hexokinase activity", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal signal transduction", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Norepinephrine metabolic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation cycle", "Ovulation cycle process", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet dense granule organization", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix constituent secretion", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Quaternary ammonium group transport", "Quinolinate metabolic process", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardiac muscle tissue development", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of corticotropin secretion", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix constituent secretion", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gastric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of cardiac muscle", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Smoothened signaling pathway involved in ventral spinal cord patterning", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron cell fate specification", "Spinal cord motor neuron differentiation", "Spinal cord patterning", "Spindle assembly", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventral spinal cord interneuron differentiation", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATF7IP", "ATG3", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C19orf70", "C1QBP", "C20orf27", "C5orf51", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2D", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CENPI", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CERS4", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTX3L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENPP1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAF1", "FAF2", "FAH", "FAM129B", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGH", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPCAL4", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS10", "INTS11", "INTS12", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "IST1", "ISYNA1", "ITGB1", "ITM2C", "ITPA", "ITPK1", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LYAR", "LYPLA1", "LYPLA2", "LYRM7", "LZTFL1", "MACF1", "MAD2L1", "MAGED2", "MAN1A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED21", "MED24", "METAP2", "METTL13", "MFN2", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL20", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL55", "MRPL58", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGT", "PIGU", "PIH1D1", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM2", "PUM3", "PURA", "PURB", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QRICH1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDX", "RECQL", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF114", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDF2L1", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYVN1", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEDC1", "TELO2", "TES", "TFAM", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM126A", "TMEM126B", "TMEM161A", "TMEM165", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP2", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT10C", "TRMT1L", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4B", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VKORC1L1", "VMP1", "VPS11", "VPS13A", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF638", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "AASDHPPT", "ABCB7", "ABCE1", "ABHD10", "ACADM", "ACADVL", "ACBD5", "ACOX1", "ACP6", "ACSL1", "ADD1", "ADK", "ADNP", "AFDN", "AFG3L2", "AHNAK", "AIFM1", "AIP", "AK3", "AKAP12", "AKAP8L", "AKT1S1", "AKT2", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH7A1", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKRD17", "ANO6", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP1M1", "AP2A1", "AP3B1", "AP3D1", "AP3S1", "APBB1", "APC", "APOL2", "APOOL", "ARCN1", "ARHGDIA", "ARHGEF7", "ARL6IP5", "ARMC10", "ASPH", "ATG3", "ATL2", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP7A", "ATXN2L", "AUP1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BASP1", "BCAS3", "BCL10", "BCL2L13", "BCLAF1", "BICD2", "BOD1L1", "BRD1", "BRD4", "BSG", "C1QBP", "CALM3", "CALR", "CAMK2G", "CAMLG", "CANX", "CAPN1", "CAPRIN1", "CAPZA1", "CARM1", "CAST", "CBFB", "CCNB1", "CCT2", "CCT3", "CCT8", "CD2AP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDK11B", "CDK2", "CDK5", "CDK5RAP3", "CDKN2A", "CEP44", "CERS2", "CFDP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHID1", "CHM", "CHMP2A", "CHMP3", "CHMP5", "CHMP7", "CHRAC1", "CIRBP", "CKAP5", "CLASP1", "CLASP2", "CLCC1", 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b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b7fc6f3d004ec4b603211b28a46d12d584f42faa --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,259 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum lumen 0.5071096401204265 2.4950622790482764 0.0125935024622165 0.9999881449674308 1.0 55 Q15293,P13674,Q9NZ08,Q8IXB1,Q96AY3,Q9Y680,O15460,P10909,O43852,Q14257,Q5JRA6,Q32P28,Q9NWM8,Q07065 14 +Protein lipid complex 0.9489553554862312 2.3626439515210476 0.0181450929595778 0.999999923731206 1.0 4 P10909 1 +Hrd1p ubiquitin ligase erad l complex 0.8479650790243939 1.967029672577842 0.0491797900318762 1.0 1.0 4 Q9BUN8 1 +Er ubiquitin ligase complex 0.8479650790243939 1.967029672577842 0.0491797900318762 1.0 1.0 4 Q9BUN8 1 +Eukaryotic translation initiation factor 4f complex 0.7212746673520049 1.8143652625592728 0.069621510081743 1.0 1.0 7 Q15056,P23588 2 +Derlin 1 retrotranslocation complex 0.7801815929937033 1.8086858191426247 0.0704998273117381 1.0 1.0 5 Q9BUN8 1 +Cytoplasmic stress granule 0.4125398017254217 1.731153780732073 0.0834243403490211 1.0 1.0 44 Q14157,Q14011,Q7Z417,Q9BWF3,Q71RC2,Q06787,P61978,P67809 8 +Microbody 0.4191333012517736 1.7204091560083965 0.0853580938417515 1.0 1.0 49 Q8N4Q0,Q9BY49,P48735 3 +Proteasome core complex beta subunit complex 0.6975830124539089 1.7054056403671796 0.0881187971238 1.0 1.0 7 P28070,P49721,P28074,P28072 4 +Lipid droplet 0.5558874718129148 1.629908512518044 0.1031208342703096 1.0 1.0 31 Q99720,P48449,Q01105,Q15042,P09455,Q07065 6 +Site of polarized growth 0.4015227465822765 1.618171466771419 0.105625650186252 1.0 1.0 44 Q99720,P80723,P51114,O75312,Q13509,Q06787 6 +Mcm complex 0.6766274316759404 1.6051885542876427 0.1084523155696706 1.0 1.0 6 Q14566 1 +Cytoplasmic ubiquitin ligase complex 0.6757932659250512 1.6043429445057165 0.108638479967305 1.0 1.0 7 Q86TM6,Q9BUN8 2 +T tubule 0.6724845119879779 1.5935503380372475 0.1110367851997902 1.0 1.0 8 P05026,O75298,P35241 3 +Distal axon 0.4105465965599095 1.5717185991581035 0.1160158267938555 1.0 1.0 53 Q99720,P80723,P51114,O75312,Q13509,Q7Z406,Q06787,Q14141 8 +Basement membrane 0.720993709602146 1.5583794019371775 0.1191433364975771 1.0 1.0 5 Q03001 1 +Ubiquitin conjugating enzyme complex 0.7463483346565805 1.5541860963183671 0.120140033011121 1.0 1.0 4 O75150,Q5VTR2 2 +Immunological synapse 0.6519638480133225 1.5296514307188205 0.1261030317504468 1.0 1.0 12 P20020,O95999,Q9UJZ1,O15400,P10644,Q96L92 6 +Synaptonemal structure 0.6561213985202959 1.512484161437207 0.130410738907035 1.0 1.0 7 Q92791,Q7Z5K2,Q9UQE7,O60216,P54652 5 +Chromocenter 0.7336159677015252 1.5016605259108375 0.133184803330804 1.0 1.0 4 P83916,Q06787 2 +Nuclear inner membrane 0.6199975277905853 1.496701431594331 0.1344709636058971 1.0 1.0 19 Q99720,Q9UH99,P62995,Q9Y2U8,Q9H1E5,O94901,Q03252,P50402 8 +Mhc protein complex 0.8184291057463512 1.4835948464136426 0.1379164374303227 1.0 1.0 3 P01889,P04439 2 +Mhc class i protein complex 0.8184291057463512 1.4835948464136426 0.1379164374303227 1.0 1.0 3 P01889,P04439 2 +Excitatory synapse 0.6434319360113674 1.451477406507325 0.1466469690935659 1.0 1.0 6 Q9UQB8,P23634,Q15334 3 +Ccr4 not core complex 0.719113478342341 1.44168844001064 0.1493902862151752 1.0 1.0 4 Q9UIV1 1 +Epsilon dna polymerase complex 0.8061883713022889 1.4363425180674332 0.1509049010384711 1.0 1.0 3 Q9NRF9,Q9NRG0 2 +Azurophil granule membrane 0.6118359631279927 1.4273702141743063 0.153473211643897 1.0 1.0 18 P27105,P42785,P07602,Q9NQX7,O15260,Q07065 6 +Hemidesmosome 0.6877369505657427 1.4159937424671207 0.156777336577444 1.0 1.0 5 Q03001 1 +Micos complex 0.6870294176481349 1.4129547086745458 0.1576690415035733 1.0 1.0 5 Q16891,Q6UXV4 2 +Postsynaptic specialization membrane 0.6297478171301037 1.4094098026458344 0.1587140271382854 1.0 1.0 11 Q99720,P52292,Q15334 3 +Basal part of cell 0.3868158296230917 1.404068255399212 0.160298525428056 1.0 1.0 48 P22413,P20020,P42785,Q12965,Q03001,Q7Z460,Q6P4Q7,P05026,Q96RT1,P08195,P23634,Q15043 12 +Protein phosphatase type 2a complex 0.6987997238290784 1.357495039154659 0.1746239686604869 1.0 1.0 4 P30154 1 +Neuron projection terminus 0.609087562147281 1.3543074005791862 0.1756383260797305 1.0 1.0 15 O75150,Q06787,Q9UQB8,Q14141 4 +Cohesin complex 0.6707384564924807 1.3428993302979215 0.1793045733352496 1.0 1.0 5 Q9UQE7,Q8WVM7 2 +Microtubule organizing center attachment site 0.7791857386360922 1.3319652692448567 0.182871601428689 1.0 1.0 3 Q9UH99 1 +Postsynaptic density intracellular component 0.6893293957019917 1.3181970744146656 0.1874376846352448 1.0 1.0 4 Q9UQB8 1 +Postsynaptic specialization intracellular component 0.6893293957019917 1.3181970744146656 0.1874376846352448 1.0 1.0 4 Q9UQB8 1 +Sperm annulus 0.7710668373942293 1.3005716293741847 0.1934051233171545 1.0 1.0 3 Q14141 1 +Cd40 receptor complex 0.7708154737840255 1.2995997617500663 0.1937381813916381 1.0 1.0 3 O14920 1 +Mcrd mediated mrna stability complex 0.6558947443586387 1.2789704538823012 0.2009074606099945 1.0 1.0 5 P11940,Q9H074 2 +Nuclear inclusion body 0.6059826639428734 1.2777595506655115 0.2013342206836299 1.0 1.0 8 O60934,Q86U42 2 +Endoplasmic reticulum quality control compartment 0.6000808669495412 1.2495660686320305 0.2114581046616841 1.0 1.0 8 Q86TM6,Q9BUN8 2 +Intermediate filament 0.5809953124510425 1.2405113467805546 0.2147863199404418 1.0 1.0 17 Q16352,O75298,P08670,Q03001 4 +Mib complex 0.5927396382259423 1.2267650251983038 0.2199109197507085 1.0 1.0 11 Q13505,Q6UXV4,Q16891,O75431,Q9NVH1 5 +Endoplasmic reticulum tubular network 0.5914630595834857 1.220454787559787 0.2222925189803963 1.0 1.0 11 P61026,Q9NP72,Q15042,Q00765,Q8NHH9,P50402 6 +Endocytic vesicle lumen 0.5888359428182409 1.1964133095180032 0.231535309995323 1.0 1.0 6 O14964,P07900,P27797,Q9Y4L1,P14625 5 +Cuticular plate 0.7429952462858346 1.1921409324739063 0.2332059894584963 1.0 1.0 3 Q12965 1 +Intrinsic component of nuclear inner membrane 0.5825285467491476 1.1654954320755508 0.2438185081667128 1.0 1.0 7 Q9UH99,Q9Y2U8,O94901 3 +Intrinsic component of postsynaptic density membrane 0.7352816830940377 1.162410427942287 0.2450687894761674 1.0 1.0 3 Q15334 1 +Specific granule membrane 0.5715387236454739 1.159048660607185 0.2464363508049711 1.0 1.0 15 O00264,Q8NHP6,P30519,Q08722,Q07065 5 +Prefoldin complex 0.6485460581368265 1.1490345592597253 0.2505417305620876 1.0 1.0 4 O15212 1 +Cytosolic region 0.5786716670571099 1.1488290127861596 0.2506264935242606 1.0 1.0 6 Q9UQB8 1 +Spectrin associated cytoskeleton 0.6443973028727099 1.1318669068509422 0.2576903935246921 1.0 1.0 4 Q01082 1 +Messenger ribonucleoprotein complex 0.6213358595267852 1.130125896980584 0.2584231789038598 1.0 1.0 5 Q06787,P51991,P67809 3 +Brca1 c complex 0.7238200975468012 1.118316721857854 0.2634317476077981 1.0 1.0 3 O60934 1 +Neuronal ribonucleoprotein granule 0.7181230873852579 1.0964449039349036 0.2728841221139921 1.0 1.0 3 Q06787,Q99729 2 +Cleavage furrow 0.5528259494476861 1.0897957942826293 0.2758031070068645 1.0 1.0 17 P35241,O95235,Q16181,Q9UL25,O95630,P11233,O75935,Q14141 8 +Apical plasma membrane 0.3516625656066715 1.084653513671877 0.2780751440467397 1.0 1.0 45 O15020,P20020,P30825,Q8TAD4,P35241,Q9NV70,Q16181,Q9P289,Q86UE4,Q9NP72,P21281,P05026,P08195,Q9Y4G8,P36543,Q15043,P23634 17 +Platelet alpha granule lumen 0.5616045144296845 1.0689300284435586 0.2851011998770851 1.0 1.0 10 P10909 1 +Meiotic cohesin complex 0.6283506751769572 1.0656141594935655 0.2865980957798189 1.0 1.0 4 O60216,Q9UQE7 2 +Hops complex 0.7090984598981427 1.06187158340029 0.288293987082918 1.0 1.0 3 Q9H270 1 +Cytoplasmic region 0.3662778862961008 1.0575279512304685 0.2902707049950273 1.0 1.0 57 Q99729,Q9UL25,O60313,Q96EV8,Q16181,Q03001,Q7Z460,P10644,Q6PJT7,Q06787,Q9UQB8,O60716,Q15334,P23246,Q8WWQ0,Q8NEB9,P04350,P78559,Q00577 19 +Sin3 complex 0.70434791058736 1.0437134668545085 0.2966179773471573 1.0 1.0 3 Q9UBU8 1 +Postsynaptic cytosol 0.5995004548723031 1.0364167592967557 0.3000077550195779 1.0 1.0 5 Q9UQB8 1 +Ccr4 not complex 0.5510062016294661 1.0195997181221943 0.3079183387462545 1.0 1.0 6 Q9UIV1 1 +Endoplasmic reticulum protein containing complex 0.3675293455441668 1.01304036277149 0.3110408820226498 1.0 1.0 61 Q86TM6,Q8TCJ2,P13674,Q9NPA0,Q8IXB1,A2RRP1,Q9BUN8,Q92643,P04439 9 +Mitochondrial pyruvate dehydrogenase complex 0.5923064412381297 1.0056614308995309 0.3145784623456089 1.0 1.0 5 O00330 1 +Prespliceosome 0.5445895357012586 0.9865977006162188 0.3238398979181809 1.0 1.0 7 Q9NQ29,Q15459 2 +Sin3 type complex 0.579722392665418 0.9520612818305768 0.3410659035483245 1.0 1.0 5 Q9UBU8 1 +Intrinsic component of presynaptic membrane 0.5797187024338737 0.9520456062870676 0.3410738530363457 1.0 1.0 5 P20020,Q92542 2 +Secretory granule membrane 0.3651789811437239 0.9470670754625116 0.3436046006432933 1.0 1.0 64 P27105,O00264,P61026,P42785,P01889,Q8NHP6,Q93050,P30519,P07602,Q9NP72,Q08722,Q92542,Q9NQX7,Q96JJ7,O15260,Q07065 16 +Annulate lamellae 0.5772254729707659 0.9414610369348037 0.346468647263126 1.0 1.0 5 Q8TD16 1 +Origin recognition complex 0.5340751200201698 0.9409690615296612 0.3467207141527861 1.0 1.0 6 Q9Y619 1 +Collagen containing extracellular matrix 0.4690496082152332 0.9331711838173972 0.3507315904266352 1.0 1.0 29 P84157,Q03001,P07602,Q96RT1,P10909,P09525,Q32P28 7 +Hulc complex 0.888851121685929 0.9251119254454158 0.3549076904490493 1.0 1.0 2 Q5VTR2 1 +Ciliary basal body 0.5236311876485094 0.921765808785895 0.3566507455440444 1.0 1.0 16 Q8WWQ0,Q05397,O43805 3 +Cell division site 0.5054835659556716 0.9052341662721064 0.3653413450195073 1.0 1.0 21 P35241,Q9BSJ2,O95235,Q16181,Q9UL25,O95630,P11233,O75935,Q14141 9 +Golgi cis cisterna 0.8810333106729993 0.8982053353169919 0.3690760895087233 1.0 1.0 2 Q08379 1 +Wash complex 0.6623597415845115 0.8849269351142257 0.3761960396580328 1.0 1.0 3 Q12768,P52907 2 +Chitosome 0.6560944125392395 0.8615729094932609 0.3889225839084156 1.0 1.0 3 Q96EV8 1 +Platelet alpha granule 0.5149559515865516 0.8586289400675541 0.390545266285887 1.0 1.0 14 P10909,Q9NUQ9,Q96JJ7,Q6UXV4 4 +Rna cap binding complex 0.5511882340056304 0.8318207917489482 0.4055101061578439 1.0 1.0 5 Q06787 1 +Caveola 0.5037527910902335 0.8025143051998758 0.4222555168441566 1.0 1.0 14 Q9UNF0,P05026,P09601,P23634,Q8WTV0 5 +Inclusion body 0.4534440802189864 0.7929324095516828 0.4278172035510017 1.0 1.0 28 O60934,Q9UL15,O14641,P10909,P12270,P13807,Q86U42 7 +Histone deacetylase complex 0.4881814967876203 0.7743577831070104 0.4387192417336076 1.0 1.0 19 Q9UBU8,Q9UEE9 2 +Early endosome membrane 0.3408650826264864 0.7736669497361498 0.439127769433322 1.0 1.0 42 O14964,P04439,Q92783,P01889,Q9UL25,Q9HC07,O60749,Q96L92,P10321,O60493,O15400,Q15043,Q15334 13 +Intrinsic component of plasma membrane 0.3586008511437717 0.7733409117822646 0.4393206494417709 1.0 1.0 72 Q8NAN2,P01889,Q86UP2,Q9NR28,Q96QD8,Q13308,Q8NHP6,O14920,P05026,Q9Y4G8,Q8WTV0,O00264,P10586,Q9UIQ6,O43657,Q08722,Q15334,P27105,P22413,P20020,P04439 21 +Parallel fiber to purkinje cell synapse 0.8402447314751871 0.7607498090401167 0.4468065181324383 1.0 1.0 2 P23634 1 +Septin cytoskeleton 0.5275523867954955 0.7341770392385529 0.4628408453997197 1.0 1.0 5 Q14141 1 +Rpap3 r2tp prefoldin like complex 0.4908484868005063 0.7338884597566536 0.4630167210399367 1.0 1.0 8 O15212,P19388,Q9UHV9 3 +Hippocampal mossy fiber to ca3 synapse 0.5255682255543186 0.7260839775730789 0.4677872907302354 1.0 1.0 5 Q96EV8,P47756,O60716 3 +Nuclear stress granule 0.616429410838021 0.7166656366067223 0.4735804340001488 1.0 1.0 3 Q92797 1 +Retromer complex 0.4839943943430228 0.7026689483092806 0.482262083229624 1.0 1.0 8 O75436,O60493 2 +Myosin filament 0.6116967018021269 0.699784120904726 0.4840621328254242 1.0 1.0 3 Q7Z406,P35579 2 +Iswi type complex 0.4796285947378838 0.6829138523076369 0.4946612802274335 1.0 1.0 8 Q9NRG0 1 +Presynaptic active zone 0.4799221689334408 0.6789652805099121 0.4971598610400358 1.0 1.0 12 P20020,P23634,Q07021 3 +Nuclear pore nuclear basket 0.4755475940439039 0.6645462577395264 0.506340752854977 1.0 1.0 8 Q8NFH5,Q13257,Q9NPA8 3 +Ribbon synapse 0.5943556613396883 0.6388408730922576 0.5229264556371758 1.0 1.0 3 P56545,P11142 2 +A band 0.5177244280400006 0.6257439300108025 0.5314829140482837 1.0 1.0 4 Q03001 1 +Contractile ring 0.5174017779605363 0.6245373367989975 0.5322747580023737 1.0 1.0 4 O43663,P46939 2 +Endoplasmic reticulum tubular network membrane 0.5882450652635023 0.6177385563760031 0.5367476918569718 1.0 1.0 3 Q8NHH9 1 +Dna polymerase complex 0.464086497985368 0.6094353871175355 0.5422358881122966 1.0 1.0 9 Q9NRG0 1 +Dendrite cytoplasm 0.4646532488056292 0.6075403279739496 0.5434923878448061 1.0 1.0 12 P23246,Q15334,Q6PJT7,Q9UQB8,Q00577 5 +Spectrin 0.512596108275373 0.6066442459827531 0.544087030128334 1.0 1.0 4 Q01082,O15020 2 +Smooth endoplasmic reticulum 0.4616699107528674 0.5957407837028048 0.5513484083127294 1.0 1.0 10 Q86TM6 1 +Lumenal side of endoplasmic reticulum membrane 0.4595490728979095 0.5935705982886464 0.5527993509404621 1.0 1.0 8 P01889,P04439 2 +Intrinsic component of presynaptic active zone membrane 0.5053268218969375 0.5798690042542723 0.562002959429194 1.0 1.0 4 P20020 1 +Presynaptic active zone membrane 0.5053268218969375 0.5798690042542723 0.562002959429194 1.0 1.0 4 P20020 1 +Integral component of presynaptic active zone membrane 0.5053268218969375 0.5798690042542723 0.562002959429194 1.0 1.0 4 P20020 1 +U12 type spliceosomal complex 0.4574223964143102 0.5743103428873332 0.5657578113939268 1.0 1.0 12 Q7RTV0,Q13435,P67809 3 +Intermediate filament cytoskeleton 0.4077797626006724 0.5741130305829099 0.5658913161216395 1.0 1.0 30 Q16352,O75298,Q03001,Q9H6U6 4 +Nuclear periphery 0.3149782544523909 0.5697828437208011 0.5688249931554088 1.0 1.0 55 Q15233,Q96T88,P12270,P02545,Q13573,Q8N1F7,Q9UJX5,O60216,P60900,Q8WXF1,Q9UQE7,O75400,P23246,P08670,P80723,Q7RTV0,Q5BKZ1,P22626,Q8WVM7,P61962 20 +Nurd complex 0.4534606219298035 0.5670425187052254 0.5706852944848209 1.0 1.0 8 Q13547,Q8WXI9 2 +External encapsulating structure 0.3938260433739202 0.5587894683135043 0.5763054108947783 1.0 1.0 32 P84157,Q03001,P07602,Q96RT1,P10909,P09525,Q32P28 7 +Exocyst 0.4954191371070295 0.5439802754764899 0.5864550462032954 1.0 1.0 4 Q9NV70 1 +Intraciliary transport particle b 0.7654656696125106 0.5267477772575452 0.59836875256621 1.0 1.0 2 Q9BW83 1 +Intraciliary transport particle 0.7654656696125106 0.5267477772575452 0.59836875256621 1.0 1.0 2 Q9BW83 1 +Mitotic cohesin complex 0.763766145479268 0.5217842482571711 0.6018205581669365 1.0 1.0 2 Q9UQE7 1 +Mediator complex 0.4391214936883946 0.5193698036820662 0.6035028844389556 1.0 1.0 6 Q13503,Q9NYF8 2 +Proton transporting v type atpase complex 0.4438855121348162 0.5132987270701507 0.6077423742720918 1.0 1.0 12 Q8N511,P21281,Q93050 3 +Neuron projection cytoplasm 0.3738419675278517 0.5088449705670605 0.6108608948558119 1.0 1.0 34 Q96EV8,P23246,Q06787,Q99729,Q00577,Q03001,Q9UL25,P78559,O60313,Q6PJT7,Q9UQB8,Q15334 12 +Nuclear chromosome 0.3367477033707337 0.4891537705266384 0.6247328358419799 1.0 1.0 78 Q13547,Q9NRG0,Q13416,Q92791,Q7Z5K2,P15927,Q92878,Q9UEE9,Q9UQE7,Q9Y619,Q9UBU8,Q9NRF9,Q14566,P33991,Q9UNS1,Q9BRT9 16 +Plasma membrane raft 0.4333195459732729 0.4836475789235998 0.6286360020807351 1.0 1.0 18 Q9UNF0,P10644,P05026,P09601,P23634,Q8WTV0 6 +Presynaptic membrane 0.4335454312392665 0.469845524934267 0.6384653863823848 1.0 1.0 15 Q96CX2,Q06787,P20020,Q92542 4 +Cortical endoplasmic reticulum 0.743711760707003 0.4646577204039581 0.6421765902619498 1.0 1.0 2 P50402 1 +Proton transporting two sector atpase complex 0.4075983479581012 0.4423727627241149 0.6582194854011791 1.0 1.0 25 Q8N511,P00846,P21281 3 +U2 snrnp 0.4250387934295764 0.4303071764073593 0.6669722074768296 1.0 1.0 14 Q12874,Q7RTV0,O43719,Q13435,P08579,Q15459 6 +Spliceosomal complex 0.3713003638811835 0.4281303460888372 0.6685562243573004 1.0 1.0 112 Q9Y5S9,Q8WWY3,Q15459,Q96I25,P52756,Q8TBF4,Q12874,Q96E39,Q07955,O43719,Q9NQ29,Q13573,P61978,P62312,P54105,O60306,O43390,P62995,P51991,Q8IWZ8,Q9Y2W2,Q15637,P19338,P67809,Q96DF8,P38159,Q9Y3C6,Q92620,P98179,O75400,P31942,O43172,Q96BP3,O75934,Q13435,Q53GS9,Q7RTV0,Q9UJV9,P11940,Q14011,P22626,O60506,P52597,Q9P2K5 44 +Intrinsic component of postsynaptic specialization membrane 0.4616368130881531 0.4277213001676107 0.6688540403474867 1.0 1.0 4 Q15334 1 +Intrinsic component of endoplasmic reticulum membrane 0.3006435323991209 0.4216560248336405 0.6732761067535753 1.0 1.0 56 Q86TM6,Q9NPA0,Q5H8A4,P49069,P01889,Q9BUN8,O75298,Q9C0E8,Q86UP2,Q92643,Q9Y282,Q9Y679,P10321,P04439 14 +Haus complex 0.5259137901167055 0.4166792885545117 0.676913005570088 1.0 1.0 3 Q9H6D7 1 +Oxidoreductase complex 0.2984767602172372 0.4140769875743132 0.6788177254652743 1.0 1.0 55 O00330,P13674,O43676,O96000,O43837,P03886 6 +Trans golgi network transport vesicle membrane 0.4564625850340051 0.4108671661457863 0.6811699394125086 1.0 1.0 4 P09496,Q00610,O43747 3 +Respirasome 0.2915345630844981 0.4052666484079854 0.6852815190895547 1.0 1.0 43 P00403,O96000,P03886 3 +Dendrite membrane 0.4529110258353992 0.399461135034956 0.6895534552904197 1.0 1.0 4 P20020 1 +Neuron to neuron synapse 0.3046399814311262 0.3855824026261962 0.6998059679649584 1.0 1.0 62 Q99720,Q96EV8,P51114,Q06787,P51991,Q01082,Q9HD26,P35611,Q9UQB8,P23634,Q15334 11 +Main axon 0.4112081423519282 0.381131869653613 0.7031054003678454 1.0 1.0 10 P04350,Q01082,Q15334 3 +Atpase complex 0.3344483510118179 0.373956615147989 0.7084365942854811 1.0 1.0 37 Q9NRG0,Q9UEE9,Q8WXI9 3 +Cell body membrane 0.5102140955690162 0.3710462290752344 0.7106030996365122 1.0 1.0 3 P20020 1 +Proton transporting v type atpase v1 domain 0.4026663257320182 0.3668843491735575 0.7137052861916979 1.0 1.0 7 P36543,P21281 2 +Mrna cleavage and polyadenylation specificity factor complex 0.4068747631841387 0.359753253504371 0.7190316640209362 1.0 1.0 11 Q9NP77,Q8N684,Q92797,Q6UN15 4 +Cytoplasmic side of membrane 0.3565574120965404 0.3567554949867618 0.7212748565138325 1.0 1.0 33 P20020,O14920,Q9NR28,P62942,Q05397,Q9NV70,Q15334 7 +Tubular endosome 0.438140154720222 0.3535209974300283 0.7236978900453537 1.0 1.0 4 O75436 1 +Voltage gated calcium channel complex 0.6985044187627278 0.3468453019793854 0.7287075412119299 1.0 1.0 2 P62942 1 +Brush border membrane 0.4222524668254581 0.3422434156432239 0.7321677147891472 1.0 1.0 5 Q6P1M0,P40855,Q04656,Q9UHB6 4 +Aggresome 0.396839168924946 0.3311397619331002 0.7405389185849327 1.0 1.0 9 O14641,P28340,O95817 3 +Nuclear lamina 0.4185096971759266 0.3302782787688904 0.7411897039614654 1.0 1.0 5 O14936,P12004,P02545,P20700 4 +U1 snrnp 0.3954184341670164 0.3201564554185225 0.7488497307635573 1.0 1.0 10 P62316,P08621,O75400,Q9NQ29,P08579 5 +Gamma secretase complex 0.6866077498300374 0.3186740183056123 0.7499737186224633 1.0 1.0 2 Q92542 1 +Pwp2p containing subcomplex of 90s preribosome 0.4134991730090656 0.3145396304994247 0.7531112218454701 1.0 1.0 5 Q9NYH9 1 +Paraspeckles 0.3858660548304877 0.3140657411599662 0.7534711085898984 1.0 1.0 6 Q8WXF1,P23246,Q15233 3 +Cortical cytoskeleton 0.3113175753202389 0.3085208240529565 0.7576860572372104 1.0 1.0 39 P35241,Q14019,Q01082,Q12965,Q14247,Q7Z460,Q13813,O15020,Q14847,P46939,Q00013,Q15334 12 +Ciliary plasm 0.3945137586742638 0.308151349906829 0.7579671694262753 1.0 1.0 12 Q8WWQ0,Q16181,Q8NEB9,P04350 4 +Zonula adherens 0.4868470462935196 0.307709605339322 0.7583033101402652 1.0 1.0 3 O60716 1 +Endoplasmic reticulum golgi intermediate compartment 0.2797396527387679 0.3064605170676012 0.7592540373280581 1.0 1.0 50 Q14789,Q8N511,Q9Y282,Q08379,P33908,P80303,O15260,Q9NYU2 8 +Mitochondrial small ribosomal subunit 0.3940453340818535 0.3013227182907366 0.7631684187919563 1.0 1.0 16 Q9BYN8 1 +Sarcolemma 0.3759485637889607 0.2961096279872107 0.7671463614612852 1.0 1.0 26 Q96EV8,P35241,O75298,Q92542,P05026,Q96QD8 6 +Apical junction complex 0.3786753865363028 0.2947596931903449 0.7681774592525044 1.0 1.0 25 Q9UDY2,Q4VCS5,Q86UE4,P61586,Q92797,P25054,Q9Y4G8,O43815,O60716,P35221 10 +Multivesicular body membrane 0.3826793309505413 0.2943817370416369 0.7684662206892992 1.0 1.0 7 O14964,Q9NZZ3,Q8WUX9,Q9Y3E7 4 +Nadh dehydrogenase complex 0.3842899902500692 0.2875114418845074 0.773720742255658 1.0 1.0 22 O96000,P03886 2 +Cell trailing edge 0.4018373596461383 0.2792001376352029 0.780091238018672 1.0 1.0 5 P35579,O75955,Q14254,P15311 4 +Outer mitochondrial membrane protein complex 0.3860766626439498 0.2695771472597975 0.7874855834861356 1.0 1.0 16 Q13505,Q6UXV4,Q9NX63,Q16891,O75431,Q9NVH1 6 +Apical part of cell 0.2833553657685579 0.2689153964216613 0.7879947886260008 1.0 1.0 56 O15020,P20020,P30825,Q8TAD4,P35241,Q9NV70,Q16181,Q9P289,Q86UE4,Q9NP72,P21281,P05026,P08195,O14641,Q9Y4G8,P36543,Q15043,P23634 18 +Lamin filament 0.4711824688465507 0.2686079378118117 0.7882314032368267 1.0 1.0 3 P02545 1 +Transcription factor tfiiic complex 0.4081632653061167 0.2684766458280019 0.7883324491391868 1.0 1.0 4 Q9Y5Q8,Q9Y5Q9,Q12789 3 +Rna polymerase iii transcription regulator complex 0.4081632653061167 0.2684766458280019 0.7883324491391868 1.0 1.0 4 Q9Y5Q8,Q9Y5Q9,Q12789 3 +Tight junction 0.3810011758496266 0.2654541650319689 0.7906596145842755 1.0 1.0 21 P55196,Q9UDY2,Q4VCS5,Q86UE4,Q92797,P25054,Q9Y4G8,O43815 8 +Sperm connecting piece 0.6621346023113577 0.2648113943923731 0.7911547587147847 1.0 1.0 2 P10644 1 +Blood microparticle 0.3848125559789894 0.2646454833371012 0.7912825783162474 1.0 1.0 16 P10909,Q5TA45 2 +Transcription regulator complex 0.2949953579125536 0.2570883623002581 0.7971105612291143 1.0 1.0 66 Q8N9N2,P35269,Q15233,P13984,Q99729,P12956,P53999,P18074,P45973,Q13951,P24941,Q8WXI9,Q13330,P16220,Q96T58,Q13547,P23246,P42224,Q14839,Q13503,Q03701,P17096,P23193,Q96PK6 24 +Phagocytic vesicle 0.2736814861373934 0.2533062526320693 0.80003156473754 1.0 1.0 43 O14964,P61026,P08670,Q6ZWJ1,P01889,P04439,Q9ULC3,Q12965,Q93050,P50995,O60493 11 +Cilium 0.3082398348159363 0.2508356870012568 0.8019411491762574 1.0 1.0 77 Q8WWQ0,P28070,P61026,Q9NUQ9,P04350,O43805,Q9GZT3,P05026,Q05397 9 +Tertiary granule 0.2885042175413571 0.248026142856735 0.8041141795789604 1.0 1.0 41 O15400,P42785 2 +Mitochondrial tricarboxylic acid cycle enzyme complex 0.3650082902628873 0.2440524509390571 0.8071901978087419 1.0 1.0 6 O43837 1 +Pericentric heterochromatin 0.3657398268635943 0.2377019510549135 0.8121122703165145 1.0 1.0 7 P83916 1 +Respiratory chain complex iv 0.373557356320792 0.2365152346790493 0.8130328870184307 1.0 1.0 11 P00403 1 +Dendritic spine membrane 0.4572662060580273 0.2362984080563987 0.8132011221532942 1.0 1.0 3 P20020 1 +Dopaminergic synapse 0.647858599592118 0.2360517257194941 0.813392532730032 1.0 1.0 2 P20337 1 +Eukaryotic translation initiation factor 2 complex 0.4556273376402665 0.2326490984496179 0.816033898163961 1.0 1.0 3 P20042,Q9BY44 2 +Sperm principal piece 0.4555623656953165 0.2325051100509796 0.8161457187104879 1.0 1.0 3 P23634 1 +Schaffer collateral ca1 synapse 0.3760856220799109 0.2322712162366429 0.8163273672545377 1.0 1.0 15 Q16352,Q96EV8,Q9UQB8 3 +Proximal dendrite 0.6447994561522827 0.2301516614824826 0.8179739221293683 1.0 1.0 2 Q6Y7W6 1 +Cop9 signalosome 0.3666948873120484 0.2256168985839632 0.821499396541101 1.0 1.0 9 Q99627,P62993,Q9BT78 3 +Recycling endosome 0.3109321151330878 0.2170761409488675 0.8281490074028559 1.0 1.0 37 P61026,P01889,Q969E2,P04439,O15400 5 +Mitochondrial intermembrane space protein transporter complex 0.3783154726062996 0.2138389078234978 0.8306726825980708 1.0 1.0 5 Q9Y5J9,Q9Y5L4 2 +Nucleotide activated protein kinase complex 0.3860544217687088 0.2136139079907595 0.8308481527256937 1.0 1.0 4 P54646,P54619,P10644 3 +Transcription repressor complex 0.3675348521771275 0.2113535138905665 0.832611427873275 1.0 1.0 12 Q96T58 1 +Nucleotide excision repair complex 0.6281441196465047 0.1996837888258843 0.8417278930766532 1.0 1.0 2 P28340 1 +Actin based cell projection 0.2815148272236275 0.1971704197752282 0.8436941778120357 1.0 1.0 41 P35241,P61086,P51114,Q06787,Q12965,Q13509,Q7Z7E8,P21281,P46939,Q9UQB8,P36543,Q00013 12 +Integral component of synaptic vesicle membrane 0.3487271653590327 0.1944267654712989 0.8458417339608955 1.0 1.0 6 P20020 1 +Clathrin complex 0.6240652617267224 0.1926520887338827 0.8472314480750196 1.0 1.0 2 P09496 1 +Cell cortex region 0.360002775666751 0.1918313387784386 0.8478743220336082 1.0 1.0 11 P09496,Q7Z460,Q14203,O75122,O60716 5 +Stereocilium bundle 0.3434293544234518 0.1793043889420579 0.8576987008245716 1.0 1.0 6 Q12965,Q00013 2 +Potassium channel complex 0.6128484024473209 0.1741929394621292 0.8617138342040906 1.0 1.0 2 Q96ER9 1 +Photoreceptor ribbon synapse 0.6101291638341325 0.1699121896353876 0.8650791945753677 1.0 1.0 2 P11142 1 +9plus2 motile cilium 0.3578887445002467 0.1686810725912213 0.8660475073153404 1.0 1.0 20 Q9GZT3,Q16181,P05026,Q14141 4 +Neuron projection membrane 0.350282533916405 0.1680468175025943 0.8665464477122677 1.0 1.0 10 Q12965,P20020,Q01082 3 +Extrinsic component of cytoplasmic side of plasma membrane 0.3554722638398676 0.1678845279395749 0.8666741222789245 1.0 1.0 13 A0FGR8,Q9Y5X3,Q96A49,P08754,P61586,Q05397,Q15334 7 +Dendrite terminus 0.4219653179190814 0.1652420917970573 0.8687534361493523 1.0 1.0 3 P07900,Q7L576 2 +Dendritic growth cone 0.4219653179190814 0.1652420917970573 0.8687534361493523 1.0 1.0 3 P07900,Q7L576 2 +Mismatch repair complex 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 1.0 3 P43246,P52701 2 +Acrosomal membrane 0.6043507817810998 0.1610670934416271 0.8720405574405041 1.0 1.0 2 P35613 1 +Protein kinase complex 0.3549835935372659 0.1610110363389154 0.8720847083143495 1.0 1.0 21 O14920,P18074 2 +Multivesicular body 0.3521692894339918 0.1537048125059725 0.8778424900477804 1.0 1.0 14 O14964,Q9NP79,Q8WUX9,Q9Y3E7,P10644 5 +Platelet dense tubular network membrane 0.5941536369816518 0.1462900609734315 0.8836924116444727 1.0 1.0 2 Q9H4M9 1 +Platelet dense tubular network 0.5941536369816518 0.1462900609734315 0.8836924116444727 1.0 1.0 2 Q9H4M9 1 +Specific granule 0.31903995661648 0.1448255651051834 0.8848485969859843 1.0 1.0 33 O00264,Q8NHP6,P30519,Q08722,P50995,Q07065 6 +Organelle membrane contact site 0.3473267646023781 0.1328950526604657 0.8942763796045241 1.0 1.0 16 Q8NHP6 1 +Catalytic step 2 spliceosome 0.2738886614555288 0.1315784271429524 0.8953177497940297 1.0 1.0 62 Q9Y5S9,Q12874,Q07955,O60306,Q13573,P61978,O43390,P51991,Q96DF8,P38159,Q9Y3C6,Q92620,Q96BP3,Q13435,Q9UJV9,P11940,O75934,P22626,O60506,P52597,Q15459 21 +Gap junction 0.3412725416808526 0.1286237943514648 0.8976553375322776 1.0 1.0 5 Q99797,Q08554,Q07157,Q69YQ0 4 +Lumenal side of membrane 0.3350288877396775 0.1253148955885284 0.9002742601674154 1.0 1.0 10 P01889,P04439 2 +Lateral plasma membrane 0.3424738130801545 0.119261750130465 0.9050679861400936 1.0 1.0 22 P05026,O14641 2 +Endoribonuclease complex 0.3358657152103823 0.1103334950082539 0.912144894240924 1.0 1.0 13 O15091,Q9UPY3 2 +Npbaf complex 0.3193988565008869 0.108972813973547 0.9132240532032958 1.0 1.0 7 Q8TAQ2,P51532,Q96GM5 3 +Spindle pole centrosome 0.313967030114982 0.1050247873428379 0.9163561400312188 1.0 1.0 6 Q15398,P50402 2 +Cell surface 0.2841562705450235 0.0955998866191464 0.9238383552539556 1.0 1.0 74 P22413,Q07021,O43847,P01889,O75298,Q4VCS5,Q08722,P55899,P10909,P04439,P09525,Q8WTV0 12 +Inner mitochondrial membrane protein complex 0.2893025700135438 0.0880171614458561 0.9298630362174284 1.0 1.0 79 P00846,P00403,O96000,Q9NVH1,Q8NE86,P03886 6 +Condensed chromosome centromeric region 0.2727088446307176 0.086233602419322 0.9312807193196132 1.0 1.0 66 P33981,Q96JM3,Q9UEE9,Q96EE3,Q8NFC6,Q13257,P12270,O75935,Q96DY7,Q8NFH4,Q16181,Q7Z460,P25054,P45973,Q96IY1,Q13416,Q8WUX9,Q9NZZ3,Q9Y3E7,Q9Y6G9,Q14141,Q8IWS0 22 +Vcp npl4 ufd1 aaa atpase complex 0.3047593737848855 0.0853498263714309 0.9319832802962846 1.0 1.0 6 Q96CS3,O94888 2 +Ubiquitin ligase complex 0.2561706699036331 0.0788635703148894 0.9371411396355658 1.0 1.0 54 Q86TM6,Q13042,Q92990,O75150,Q9BUN8,Q5VTR2,Q92564 7 +Nuclear pore central transport channel 0.3057823129251771 0.0769508310402993 0.9386626600684074 1.0 1.0 4 Q8NFH5,P37198,P61970 3 +Rna polymerase ii core complex 0.3000327809277422 0.0759160905766448 0.9394858553729032 1.0 1.0 6 P62875,P52434 2 +Amphisome membrane 0.2995468749853253 0.0749718924259516 0.9402370755309596 1.0 1.0 6 Q9NZZ3,Q8WUX9,Q9Y3E7 3 +Amphisome 0.2995468749853253 0.0749718924259516 0.9402370755309596 1.0 1.0 6 Q9NZZ3,Q8WUX9,Q9Y3E7 3 +Condensed nuclear chromosome 0.3294744310932064 0.0742419193106254 0.9408178910801756 1.0 1.0 20 Q92791,Q7Z5K2,O60885,Q92878,Q15050,Q9UQE7,P54652,O60216,P53350 9 +Mitotic spindle astral microtubule 0.5251529571720003 0.0729308397017898 0.9418611527486735 1.0 1.0 2 Q15691 1 +Vesicle tethering complex 0.3287064308908932 0.0725767092479612 0.9421429611593264 1.0 1.0 19 A2RRP1,Q9H270,Q9H267,Q9UID3,Q6NUQ1,Q9UPT5,Q9NV70 7 +Sarcoplasmic reticulum membrane 0.3140181112599677 0.0679048638584883 0.945861366893507 1.0 1.0 11 O75298 1 +Signal peptidase complex 0.3437606256375358 0.0648232411302026 0.9483147366190888 1.0 1.0 3 P61009,Q15005 2 +P body 0.3137474830131648 0.0600271139540159 0.9521340398098868 1.0 1.0 29 Q9NPI6,P19474,Q9UIV1 3 +Elongator holoenzyme complex 0.499320190346712 0.0561105030614652 0.9552537768888604 1.0 1.0 2 O95163 1 +Cortical actin cytoskeleton 0.3098785951605408 0.0556540347737023 0.9556174176477308 1.0 1.0 30 P35241,Q14019,Q01082,Q12965,Q14247,Q13813,O15020,Q14847,P46939,Q15334 10 +Zona pellucida receptor complex 0.294658046954742 0.0541008302395647 0.9568548307825786 1.0 1.0 5 P49368,P78371,P17987,P50990 4 +Endoplasmic reticulum exit site 0.3185343212710716 0.0530894609234909 0.9576606285766232 1.0 1.0 16 P04439,Q5JRA6,O95486 3 +Filopodium 0.3169075120160656 0.0447615804110989 0.9642973487706292 1.0 1.0 25 Q9UQB8,P35241,P51114,Q13509,Q7Z7E8,P46939,Q06787,P61086 8 +Mitotic spindle microtubule 0.2819250133126988 0.0439333736651791 0.9649575126365016 1.0 1.0 6 Q9H6D7 1 +Rna polymerase ii transcription regulator complex 0.3114177098777618 0.0430691513212733 0.9656464101509248 1.0 1.0 28 P42224,P23246,P23193,P35269,Q14839,P13984,Q99729,Q13503,Q03701,P17096,P18074,P16220,Q13951 13 +Flotillin complex 0.2791014295439139 0.0395326265600139 0.9684657416069242 1.0 1.0 6 O75955,Q14254,Q9ULV4,P22681,P35221 5 +Proton transporting two sector atpase complex catalytic domain 0.2984388452653776 0.0362726945022982 0.9710649222376352 1.0 1.0 11 P06576,P36543,P21281 3 +Neuronal dense core vesicle 0.4449354180829428 0.0348340113959051 0.9722120999083226 1.0 1.0 2 Q96RL7 1 +Dense core granule 0.4449354180829428 0.0348340113959051 0.9722120999083226 1.0 1.0 2 Q96RL7 1 +Rna polymerase ii holoenzyme 0.3142607260195043 0.0323587497107655 0.9741859582093284 1.0 1.0 20 Q5VT52,P23193,P35269,P13984,P62875,P52434,P18074 7 +Beta catenin destruction complex 0.2791964589717397 0.0320145410909333 0.97446045472813 1.0 1.0 7 P48729,P49841,Q9HB71,P49840,P25054,Q9UJX6 6 +Aryl hydrocarbon receptor complex 0.4218218898708417 0.0300369956226815 0.976037548232218 1.0 1.0 2 O00170 1 +Centriolar subdistal appendage 0.4041468388851208 0.0275340185099302 0.9780338072787638 1.0 1.0 2 Q14203 1 +Polar microtubule 0.3810333106730156 0.0253797844653363 0.9797520355738316 1.0 1.0 2 Q13618 1 +Ap 3 adaptor complex 0.3636981645139434 0.0243669811865758 0.9805598856974644 1.0 1.0 2 Q92572 1 +Cul4b ring e3 ubiquitin ligase complex 0.3235893949694143 0.0232168290908957 0.9814773145524004 1.0 1.0 2 Q13620 1 +Axon cytoplasm 0.3088613529666415 0.0176169817272442 0.9859444093199206 1.0 1.0 21 Q96EV8,P33176,Q03001,Q9UL25,O60313,Q6PJT7,P78559 7 +Synaptic vesicle membrane 0.3014294079483784 0.0151893109341197 0.987881149318666 1.0 1.0 16 Q96EV8,P20020,O00429,O60499 4 +Eukaryotic translation initiation factor 3 complex 0.2932571056572883 0.0094342862505397 0.992472640321723 1.0 1.0 14 Q9Y262,O75822,Q7L2H7,Q9UBQ5 4 +Translation preinitiation complex 0.2957961053265667 0.00893504016549 0.9928709642596216 1.0 1.0 15 Q9Y262,O75822,Q7L2H7,Q9UBQ5 4 +Germ cell nucleus 0.2304369327823205 0.004398215562464 0.9964907430216507 1.0 1.0 5 P29966 1 +Anaphase promoting complex 0.2740430714878532 0.0036249875441662 0.9971076847398366 1.0 1.0 10 Q9UJX5,Q9UJX3,Q13042 3 +Nuclear pore 0.2420041360479499 0.003585902828929 0.9971388696279953 1.0 1.0 52 Q8WUX9,Q8N1F7,Q8NFH4,Q8NFH5,Q9C0E2,Q9NZZ3,Q9NPA8,Q12965,Q9Y3E7,Q5SRE5,Q8TD16,Q13257,P12270,O00410 14 +Escrt iii complex 0.2277879766912722 0.0033563511693284 0.9973220242493022 1.0 1.0 5 Q8WUX9,Q9Y3E7 2 +Chromosome centromeric region 0.2836648785034939 0.0032594058144276 0.9973993750279992 1.0 1.0 85 P33981,Q96JM3,Q9UEE9,Q96EE3,Q8NFC6,Q13257,Q29RF7,O95251,P12270,O75935,Q96DY7,Q8NFH4,Q16181,Q7Z460,O60216,P45973,Q06787,P25054,Q96IY1,Q13416,Q8WUX9,Q7Z5K2,Q9NZZ3,Q9UQE7,Q9Y3E7,Q9Y6G9,P83916,Q14141,Q8IWS0,Q9NTJ3,Q8WVM7 31 +Endoplasmic reticulum golgi intermediate compartment membrane 0.3007065293647865 0.0031856285954613 0.99745824042629 1.0 1.0 27 O15260,Q8N511,Q08379,Q9Y282 4 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..07f41b431f375c5d5d6e293dbda4821a724c8c29 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Mon1 ccz1 complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Muscle myosin complex", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spherical high density lipoprotein particle", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC1", "ARMC10", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ATAD1", "ATAD3A", "ATAD3B", "ATF7IP", "ATG3", "ATG9A", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPTF", "BRD1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf73", "C19orf70", "C1QBP", "C1orf35", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CENPI", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CERS4", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTC", "CLU", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCK", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTX3L", "DUS2", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENO1", "ENPP1", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM210A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GGA2", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPR2", "GNAI3", "GNL2", "GNL3", "GNL3L", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT2", "GPAA1", "GPATCH11", "GPATCH4", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEBP2", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HP1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS10", "INTS11", "INTS12", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISOC1", "IST1", "ITGB1", "ITM2C", "ITPK1", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRPPRC", "LRRC59", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LYAR", "LYPLA1", "LYPLA2", "LYRM7", "MACF1", "MAD2L1", "MAGED2", "MAN1A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED21", "MED24", "METTL13", "MFN2", "MGME1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NF1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCIAD2", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGT", "PIGU", "PIH1D1", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLRG1", "PLS1", "PLS3", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPM1F", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK2", "PTK7", "PTPN1", "PTPRF", "PTRH2", "PUM1", "PUM2", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDX", "RECQL", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF20", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDF2L1", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT2", "SHOC2", "SIGMAR1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYVN1", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAMM41", "TAP2", "TAPBP", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEDC1", "TELO2", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM126A", "TMEM126B", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4B", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFM1", "UGGT1", "UHRF1", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VKORC1L1", "VMP1", "VPS11", "VPS13A", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", 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setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +L ascorbic acid binding 2 5 2.229448539755773 0.0257840756505853 2.3300970873786406 7.104368932038835 0.5677763323556714 0.4604224594801547 1.449059618159932 1.3886783336592343 0.918266587379424 0.3051881949297183 1.0 0.0117676307173903 0.0075942890928168 0.0472723399635447 +Rna strand annealing activity 3 5 2.201436771983946 0.0277051181976015 2.3592233009708736 4.827669902912621 0.6605691137249392 0.4146825675209687 1.2354345089339345 0.3776670951052438 0.9657668988233084 0.309644633238528 1.0 1.0 0.0001387808195727 2.7039815749173976e-05 +Peptide antigen binding 3 7 2.02243490306508 0.0431314423255906 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.0711332726649859 0.009201700056446 0.0052676758380378 0.004988841333209 +Dynein complex binding 4 7 2.0172353986802256 0.0436709536028194 2.79126213592233 6.543689320388349 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0.0445602183527292 0.0281854945142632 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..acb879f19c9634679a2f21f672838b518331cb13 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 1351, + "title": "Average number of proteins per term", + "value": 15.80458919319023 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..59619cf2e1fc9feb81d3e6f0d953397992808beb --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..203ac7d1bd688a7166a1fab86004915d3319349d --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,346 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +L ascorbic acid binding 0.8826767475932678 2.229448539755773 0.0257840756505853 0.9999999999999996 0.8105088305903762 5 P13674,Q32P28 2 +Rna strand annealing activity 0.8757153829825913 2.201436771983946 0.0277051181976015 1.0 0.8105088305903762 5 Q15056,Q06787,P23588 3 +Procollagen proline dioxygenase activity 0.9059685635257332 2.1962183486032334 0.0280763186722357 1.0 0.8105088305903762 4 P13674,Q32P28 2 +Peptidyl proline dioxygenase activity 0.9059685635257332 2.1962183486032334 0.0280763186722357 1.0 0.8105088305903762 4 P13674,Q32P28 2 +Isocitrate dehydrogenase activity 0.8681159883452286 2.0472377529396293 0.0406347463107645 1.0 0.8105088305903762 4 O75874,P48735 2 +Peptide antigen binding 0.7671789993063921 2.02243490306508 0.0431314423255906 1.0 0.8105088305903762 7 P04439,Q15392,P55899 3 +Dynein complex binding 0.7660203859987208 2.0172353986802256 0.0436709536028194 1.0 0.8105088305903762 7 Q06787,Q8TD16,P12270,Q9UQE7 4 +Antigen binding 0.7569649676011565 1.9851034303976671 0.047132965224977 1.0 0.8105088305903762 8 P04439,Q15392,P55899 3 +Monooxygenase activity 0.7523205815470779 1.9742830345830653 0.0483495688897592 1.0 0.8105088305903762 9 Q15800,P61457,Q16850,Q14534,P30519 5 +Mhc protein complex binding 0.7532432709918154 1.968143438082315 0.0490515360836378 1.0 0.8105088305903762 8 Q9NUQ9,P05026 2 +Amyloid beta binding 0.7382347835537891 1.920822333449288 0.0547541098705404 1.0 0.8105088305903762 10 O00264,O15212,P10909,Q9NQX7,Q8WTV0 5 +Mhc protein binding 0.7405612783306292 1.9199274010785672 0.0548670702432949 1.0 0.8105088305903762 9 Q9BUN8 1 +Endodeoxyribonuclease activity producing 5 phosphomonoesters 0.7383946993149614 1.8865878619198848 0.0592157806256841 1.0 0.8105088305903762 6 Q9UQ84,Q9UPY3 2 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.9238354301258088 1.8862015918894277 0.059267794100499 1.0 0.8105088305903762 3 Q16850,Q14534 2 +Signal recognition particle binding 0.7329055125464623 1.861859728814078 0.0626228647639783 1.0 0.8105088305903762 6 Q9BUN8 1 +Aldehyde dehydrogenase nad p plus activity 0.7297707969239754 1.853187474099059 0.0638554923965692 1.0 0.8105088305903762 7 P30837,O94788 2 +Annealing activity 0.7252521639334543 1.8396891939706972 0.0658138809276378 1.0 0.8105088305903762 8 Q15056,Q06787,P23588 3 +Structural constituent of synapse 0.7202083631012269 1.8044415458401055 0.071162115023885 1.0 0.8105088305903762 6 Q16352,Q15334 2 +Sirna binding 0.8030096220577965 1.7859814483580634 0.0741022619584867 1.0 0.8105088305903762 4 Q06787 1 +Microtubule minus end binding 0.8015773769229855 1.7801683866062905 0.0750484074236168 1.0 0.8105088305903762 4 Q9H6D7 1 +Flap endonuclease activity 0.8009631774245338 1.777674726571117 0.0754572928802983 1.0 0.8105088305903762 4 Q9UQ84 1 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.6974298191208393 1.7690641543026933 0.0768831690331732 1.0 0.8105088305903762 13 Q8N4Q0,Q15392,Q9BY49 3 +Procollagen proline 4 dioxygenase activity 0.8850759308559542 1.739286115420436 0.0819844483550062 1.0 0.8105088305903762 3 P13674 1 +Peptidyl proline 4 dioxygenase activity 0.8850759308559542 1.739286115420436 0.0819844483550062 1.0 0.8105088305903762 3 P13674 1 +Adrenergic receptor binding 0.8813328799727984 1.7250191232660472 0.0845240262704485 1.0 0.8105088305903762 3 Q9Y4G8,Q07021 2 +Oxidoreductase activity acting on a heme group of donors 0.6988700284361243 1.711350327735322 0.0870164609241346 1.0 0.8105088305903762 7 P00403,Q7KZN9 2 +Mhc class ii protein complex binding 0.6978255570041212 1.706526163960675 0.0879101592126674 1.0 0.8105088305903762 7 P05026 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.6029324710648776 1.6541649937915406 0.0980939933841256 1.0 0.8240158523253317 26 Q9NWT6,P13674,Q15800,P61457,Q16850,Q6UW02,Q14534,P30519,O15460,O75845,Q32P28 11 +5 3 exonuclease activity 0.6834138752552779 1.6449211277899562 0.0999860772885314 1.0 0.8240158523253317 8 Q9UQ84 1 +Fad binding 0.6719398533631685 1.5909854832962973 0.1116128427926572 1.0 0.839892242282595 8 Q15392,O95831,Q14534 3 +Lipopolysaccharide binding 0.6684574490327158 1.5701519480393102 0.1163797655333402 1.0 0.839892242282595 7 Q8WTV0 1 +Mrna methyltransferase activity 0.7227700166002877 1.565954741223382 0.1173592130082339 1.0 0.839892242282595 5 Q96FX7 1 +Lys48 specific deubiquitinase activity 0.7219535740912112 1.5624733170469791 0.1181765270039127 1.0 0.839892242282595 5 O94966 1 +Histone lysine n methyltransferase activity 0.6639388294402035 1.5592771020661116 0.1189308088648783 1.0 0.839892242282595 9 Q9H7B4 1 +Lysine n methyltransferase activity 0.6639388294402035 1.5592771020661116 0.1189308088648783 1.0 0.839892242282595 9 Q9H7B4 1 +Sodium ion transmembrane transporter activity 0.6646196988847366 1.5522338142736862 0.1206062879369529 1.0 0.839892242282595 7 Q96QD8 1 +Oxidoreductase activity acting on the ch ch group of donors 0.5666816051461524 1.5260934655226417 0.1269865892124198 1.0 0.8481310963433417 28 Q8N4Q0,Q9BY49,Q8N8N7,Q15392 4 +Cis regulatory region sequence specific dna binding 0.4058392079835617 1.523759538632064 0.1275687903693647 1.0 0.8481310963433417 43 O00330,Q13547,P38159,P42224,Q9H7B4,O95785,Q9Y2W1,Q9Y2X9,P53999,P17096,P16220,Q13330 12 +Macrolide binding 0.6575703946842381 1.5192684094996538 0.1286949480017654 1.0 0.8481310963433417 7 Q96AY3,Q9Y680 2 +Fk506 binding 0.6575703946842381 1.5192684094996538 0.1286949480017654 1.0 0.8481310963433417 7 Q96AY3,Q9Y680 2 +Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity 0.7083615782579058 1.5044137102624586 0.1324748762776946 1.0 0.8482159139865659 5 P30837 1 +Isoprenoid binding 0.8196086563534735 1.4881449494549324 0.1367126715317113 1.0 0.867130606757474 3 O94788 1 +Structural constituent of postsynapse 0.8180489541133169 1.4821282819405808 0.1383061647822003 1.0 0.8690773424221057 3 Q16352 1 +Endodeoxyribonuclease activity 0.6449198189256626 1.468280692415214 0.1420279932888444 1.0 0.8883324950612445 9 Q9UQ84,Q9UPY3,P51530 3 +Ww domain binding 0.7897280329398724 1.3727292556982558 0.1698365306970157 1.0 0.9560381373819512 3 Q9Y4G8 1 +Protein lipid complex binding 0.6991218168309836 1.3588312283084003 0.1742000752270152 1.0 0.9765323719157571 4 Q8WTV0 1 +Transcription corepressor activity 0.3786690073392807 1.3350360641779142 0.1818645432332235 1.0 0.986453004808044 47 Q96T58,Q9UIV1,Q07021,P80723,Q15637,Q96IZ0,Q9HCD5 7 +Cytoskeleton nuclear membrane anchor activity 0.7791857386360922 1.3319652692448567 0.182871601428689 1.0 0.986453004808044 3 Q9UH99 1 +Cytoskeletal anchor activity 0.6093466864217263 1.2924246348680044 0.1962101299794767 1.0 0.986453004808044 6 Q9UQB8 1 +Mrna 3 utr binding 0.3743708279505725 1.2903998593207529 0.1969118609501974 1.0 0.986453004808044 47 Q14011,P51114,Q5VTR2,Q92804,Q01085,Q9BWF3,P35637,Q71RC2,Q06787 9 +Phosphatidic acid binding 0.7677660659639658 1.287810290006418 0.1978120094400768 1.0 0.986453004808044 3 Q9Y4G8,O60313 2 +Retinal binding 0.9901427600271916 1.2838253305290643 0.1992030784207688 1.0 0.986453004808044 2 O94788 1 +Endoribonuclease activity producing 5 phosphomonoesters 0.6001843872487892 1.2817693885136212 0.1999235555354499 1.0 0.986453004808044 13 Q8N2A8,O15091,Q9UQ84 3 +Poly g binding 0.6558282687018767 1.278684037378389 0.2010083430770053 1.0 0.986453004808044 5 Q06787 1 +Transforming growth factor beta receptor binding 0.6796963738876913 1.2782126100685358 0.2011744710673333 1.0 0.986453004808044 4 Q9Y4E8 1 +Organic cation transmembrane transporter activity 0.6781575328425171 1.2718251980814683 0.2034352338812097 1.0 0.986453004808044 4 O43772 1 +Molecular transducer activity 0.5197770746824303 1.2699452704204743 0.2041041259236116 1.0 0.986453004808044 29 Q99720,Q13308,P41214,Q9BUN8,P10586,Q08722,Q8WTV0 7 +Tap binding 0.6485510521842295 1.2473267915019397 0.2122776976838987 1.0 0.986453004808044 5 P01889,P04439 2 +Misfolded protein binding 0.5888846685299338 1.235874760366422 0.216505120184336 1.0 0.986453004808044 14 P10909,Q9BUN8 2 +Endoribonuclease activity 0.572056917136945 1.23289550645568 0.2176147521699873 1.0 0.986453004808044 19 Q8N2A8,O15091,Q9UQ84,Q5TA45 4 +Ubiquitin specific protease binding 0.5931550028099886 1.2229467539296444 0.2213498079749183 1.0 0.99350030091068 10 Q9BUN8 1 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.5833039892213109 1.220257843645327 0.222367145271267 1.0 0.9947616333161644 15 Q8N2A8,O15091,Q9UQ84,Q9UPY3 4 +L amino acid transmembrane transporter activity 0.5911216471218738 1.213012427770824 0.2251250690614226 1.0 0.9957691558248845 10 Q9Y619,P08195,Q96QD8 3 +High density lipoprotein particle binding 0.7481150364757411 1.2118939003320874 0.2255529973565107 1.0 0.9957691558248845 3 Q8WTV0 1 +Lysine acetylated histone binding 0.5920999288827391 1.211428523813323 0.2257312129471689 1.0 0.9957691558248845 8 Q03164 1 +Growth factor receptor binding 0.5878526877908784 1.2100031895003869 0.2262776690142409 1.0 0.9957691558248845 12 Q9NZ08,Q92990,Q9H2J4,Q92542,O60749,P62993 6 +Pdz domain binding 0.5862061616493487 1.1889971648196238 0.2344407826008647 1.0 1.0 10 P20020,Q9Y4G8,Q9UQB8,P23634,Q15334 5 +Molecular function activator activity 0.5844348873426457 1.1857139993794494 0.2357352640925865 1.0 1.0 11 Q8NFQ8,P05026 2 +Atpase activator activity 0.5844348873426457 1.1857139993794494 0.2357352640925865 1.0 1.0 11 Q8NFQ8,P05026 2 +Single stranded telomeric dna binding 0.6334728679464134 1.182364645696413 0.2370610450310857 1.0 1.0 5 Q92878,P15927 2 +Cation transmembrane transporter activity 0.4079336905240031 1.1739983626561306 0.2403956814563743 1.0 1.0 79 P20020,P00846,O43772,Q70HW3,Q7KZN9,Q93050,Q96ES6,Q9Y619,P00403,Q8NE86,Q9HC07,P05026,Q96QD8,P21281,Q9NW15 15 +Transferrin receptor binding 0.7322916595601556 1.1508971090812798 0.2497745672638776 1.0 1.0 3 O14920 1 +Threonine type peptidase activity 0.579026490968136 1.1489606720535088 0.2505721977584918 1.0 1.0 8 P28070,P49721,P28074,P28072 4 +Threonine type endopeptidase activity 0.579026490968136 1.1489606720535088 0.2505721977584918 1.0 1.0 8 P28070,P49721,P28074,P28072 4 +2 oxoglutarate dependent dioxygenase activity 0.5739616808445409 1.1339625295196742 0.2568102659883218 1.0 1.0 11 Q9NWT6,P13674,O15460,Q32P28 4 +Protein geranylgeranyltransferase activity 0.72696361781707 1.130398864442978 0.2583081924043042 1.0 1.0 3 Q92696,P24386 2 +Metalloaminopeptidase activity 0.570853653390356 1.12497693341313 0.2605988089425533 1.0 1.0 12 P55786 1 +Calcium channel regulator activity 0.6173574834536582 1.1130208867341067 0.2656994591205506 1.0 1.0 5 Q9UKS6 1 +Protein prenyltransferase activity 0.6358301882736361 1.0964623315608286 0.2728764991899899 1.0 1.0 4 Q92696,P24386 2 +Iron ion binding 0.5428698564872638 1.093210184564501 0.2743015264044528 1.0 1.0 20 P13674,Q15800,Q16850,Q6UW02,O15460,O75845,Q32P28 7 +S adenosylmethionine dependent methyltransferase activity 0.4257451666752707 1.086130414395376 0.2774212980327921 1.0 1.0 37 Q9H7B4,O60725,Q96FX7,Q03164,Q08J23 5 +Microtubule plus end binding 0.5649248256820575 1.0851115571427985 0.2778722492330936 1.0 1.0 10 P25054,Q7Z460,Q03001 3 +Rna polymerase core enzyme binding 0.5515842769170478 1.0831628786661636 0.2787361333527145 1.0 1.0 17 Q9H7B4,Q5BKZ1 2 +Guanylate kinase activity 0.631180591865032 1.077278174935698 0.281356009621905 1.0 1.0 4 Q00013 1 +Phosphatase regulator activity 0.5463442188092411 1.071955135768918 0.2837401836963107 1.0 1.0 18 P63151,P35269,P78318,Q01105,Q9UQ13,O43768,P30154,Q15435 8 +Histone methyltransferase binding 0.5620291656765454 1.071011583598633 0.2841642212475306 1.0 1.0 6 O95785 1 +Protein kinase a regulatory subunit binding 0.6059382010815986 1.0639957903872523 0.2873306065479255 1.0 1.0 5 Q9H3P7 1 +Metal ion transmembrane transporter activity 0.4861895002109009 1.0465499940205771 0.2953071755795016 1.0 1.0 29 P20020,Q8TAD4,Q6P4Q7,Q8NE86,Q9HC07,P05026,Q96QD8,P23634,Q15043 9 +Solute cation symporter activity 0.5553632912336569 1.0361106129387392 0.3001505415493084 1.0 1.0 8 Q96QD8 1 +P type transmembrane transporter activity 0.554463786342026 1.031831305725292 0.3021511509973873 1.0 1.0 8 P20020,P05026 2 +Rna polymerase binding 0.5131229326401235 1.027348327312888 0.3042564736872455 1.0 1.0 24 P27105,Q5VT52,Q9H7B4,Q5BKZ1,Q86U42 5 +Protein phosphatase regulator activity 0.5432433694091569 1.0243658314970436 0.3056625144221665 1.0 1.0 16 P63151,P78318,Q01105,Q9UQ13,O43768,P30154,Q15435 7 +Calcium ion transmembrane transporter activity 0.5475664182998409 1.024081230781955 0.3057969088442553 1.0 1.0 14 Q9HC07,Q8NE86 2 +Ribosomal small subunit binding 0.5506408952800441 1.0189965329271304 0.308204612514902 1.0 1.0 11 P23588 1 +Beta 2 microglobulin binding 0.9157036029911548 1.0186144238356905 0.3083860538708407 1.0 1.0 2 P55899 1 +N methyltransferase activity 0.5360687401763777 1.016335542982241 0.3094696285382285 1.0 1.0 18 Q9H7B4 1 +Gdp dissociation inhibitor activity 0.5495088763407296 1.012627441932205 0.3112381470799268 1.0 1.0 6 P52565,P55010,P24386 3 +Pyruvate dehydrogenase activity 0.5923064412381297 1.0056614308995309 0.3145784623456089 1.0 1.0 5 O00330 1 +Phosphatidylinositol 5 phosphate binding 0.6922815368922196 0.9977410252032608 0.3184049541669926 1.0 1.0 3 O60493,Q9NS86 2 +G rich strand telomeric dna binding 0.6059754010542475 0.9737983414294366 0.330156676787158 1.0 1.0 4 P22626,P15927 2 +Jun kinase binding 0.9014276002719164 0.9687090804672274 0.3326903606770537 1.0 1.0 2 Q05397 1 +Ubiquitin conjugating enzyme binding 0.5407035367929046 0.9683712657354662 0.3328589846507035 1.0 1.0 7 O75150,Q9Y679,Q92564 3 +Dioxygenase activity 0.5357165913849307 0.9636771324225404 0.335207822578774 1.0 1.0 14 Q9NWT6,P13674,O15460,Q32P28 4 +Tetrapyrrole binding 0.5225397993870177 0.9603556074472288 0.3368762722796936 1.0 1.0 19 O00264,Q16850,Q6UW02,P30519,Q8WUJ1,O43169 6 +S100 protein binding 0.5392524311063004 0.959646190520256 0.337233313481275 1.0 1.0 8 P16615,Q9HB71,Q09666,P31949,P50995,P46940 6 +Calcium channel inhibitor activity 0.8963290278721883 0.950990362949631 0.3416092679984501 1.0 1.0 2 Q9UKS6 1 +Lysophosphatidic acid phosphatase activity 0.8953093133922362 0.9474536969842114 0.34340764003291 1.0 1.0 2 Q9NPH0 1 +Cation channel activity 0.5039266996917553 0.9442218171549104 0.3450563085924896 1.0 1.0 23 P00846,Q8NE86 2 +Transferase activity transferring one carbon groups 0.343777544229862 0.9283393227485204 0.3532315824831094 1.0 1.0 50 Q8N6R0,Q9H7B4,O60725,Q96FX7,Q03164,Q9BV86 6 +Insulin receptor binding 0.5304045907744825 0.9202079637227314 0.3574640934813704 1.0 1.0 7 P22413,Q8WWQ0 2 +Oxidoreductase activity acting on the aldehyde or oxo group of donors 0.5034848671389538 0.9164523549780066 0.3594296861302752 1.0 1.0 22 O00330,P30837,O94788 3 +Histone methyltransferase activity 0.5239039497306608 0.9125092800569232 0.3615006866103811 1.0 1.0 15 Q9H7B4 1 +Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor 0.506167879201676 0.9090828101959528 0.3633064155992556 1.0 1.0 21 O00330,P30837,O94788 3 +Frizzled binding 0.8810333106730076 0.898205335317021 0.3690760895087077 1.0 1.0 2 O14641 1 +Immunoglobulin binding 0.8810333106729993 0.8982053353169919 0.3690760895087233 1.0 1.0 2 P55899 1 +Collagen binding 0.5260312639689788 0.897268287243813 0.3695757743266106 1.0 1.0 8 Q32P28 1 +Dopamine receptor binding 0.5870748299319659 0.8969940343333775 0.3697221003542812 1.0 1.0 4 Q9Y5X3,P50570,Q15334 3 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.878993881713112 0.8912125321931639 0.3728151624267608 1.0 1.0 2 Q8IXB1 1 +Glutamate receptor binding 0.5217172790653032 0.8839429466738277 0.3767270121446677 1.0 1.0 6 Q15334 1 +Notch binding 0.6606596395783906 0.8785793198957604 0.3796294126964179 1.0 1.0 3 Q9NWT6,Q13573 2 +Scaffold protein binding 0.512887739485966 0.8777579659822404 0.3800750799702994 1.0 1.0 17 P08670,O14920,P07602,Q9UQB8,Q15334 5 +Syntaxin binding 0.513708619933404 0.870223450273724 0.3841783029913934 1.0 1.0 16 Q6ZWJ1,O75150,Q9H270,Q99747,Q08379,O60499,O15400 7 +Sequence specific mrna binding 0.5171897378383727 0.8587800401377209 0.3904618816325158 1.0 1.0 7 Q08170 1 +Single stranded rna binding 0.405929581042048 0.8553365655537593 0.3923648501871373 1.0 1.0 36 Q96SI9,O14979,P51114,P23588,P31483,Q6PJT7,Q71RC2,P11940,Q06787,Q15056,O60306 11 +Atpase regulator activity 0.5164456217906069 0.8523238729827868 0.3940343594755213 1.0 1.0 8 Q9UL15,O95429 2 +Adenyl nucleotide exchange factor activity 0.5164456217906069 0.8523238729827868 0.3940343594755213 1.0 1.0 8 Q9UL15,O95429 2 +Trna methyltransferase activity 0.5133850444577789 0.8457212030356014 0.39770829195953 1.0 1.0 6 Q96FX7 1 +Amino acid transmembrane transporter activity 0.515130890959672 0.8457045581596238 0.3977175797058292 1.0 1.0 11 Q9Y619,P08195,Q96QD8 3 +Peptide binding 0.3631771311107482 0.8452109476175091 0.3979930710111525 1.0 1.0 70 Q15392,Q9NZ08,O00264,P01889,P52292,P55786,Q9UIQ6,Q96BP3,O15212,P55899,Q9NQX7,P04439,P10909,Q8WTV0 14 +N6 methyladenosine containing rna binding 0.5724489795918268 0.8382031103891833 0.4019166404722558 1.0 1.0 4 Q9H6S0,P22626,P07910 3 +Calcium ion binding 0.3765723064276031 0.8343986251604963 0.4040563917338602 1.0 1.0 81 Q15293,P22413,P80303,Q66K14,P04350,Q9Y4G8,Q96AY3,Q9Y680,Q03001,Q96D71,P50995,P33908,P09525,O43852,Q14257,Q9NWM8 16 +Lipase inhibitor activity 0.5701212975906975 0.8289080891714171 0.4071564176999707 1.0 1.0 4 P09525 1 +Symporter activity 0.5102534839695463 0.8211119146309699 0.4115825239924464 1.0 1.0 10 Q96QD8 1 +Aminopeptidase activity 0.5045268095508488 0.813679566994979 0.4158285426649817 1.0 1.0 15 P55786 1 +Prenyltransferase activity 0.5034330060425575 0.8003611295564969 0.4235015950284868 1.0 1.0 6 Q92696,P24386,P53611 3 +Translation activator activity 0.5623232824110089 0.797906207930553 0.4249249205964953 1.0 1.0 4 P11940,Q9H074 2 +Dna directed dna polymerase activity 0.501801546594663 0.7929592136154608 0.4278015862298767 1.0 1.0 6 Q9NRG0 1 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.6344974152208177 0.7819745498712647 0.4342295305604227 1.0 1.0 3 O75845 1 +Protein methyltransferase activity 0.4779538651107446 0.7714936052283661 0.4404144113441259 1.0 1.0 22 O60725,Q9H7B4,Q03164 3 +Nadh dehydrogenase activity 0.4874633938080196 0.7705225296042668 0.4409899959668051 1.0 1.0 19 O95831,O96000,P03886 3 +Nad binding 0.4496328897400475 0.7687991507638957 0.4420125531153429 1.0 1.0 28 Q16836,O75874,P30837,P48735,O43837 5 +Kinesin binding 0.4970485606609699 0.7597831161041745 0.4473842367827039 1.0 1.0 9 Q9NPI6,O60271,Q86UP2,Q15334 4 +Ribonuclease activity 0.3767936262019342 0.7595436017143333 0.4475274418922101 1.0 1.0 38 Q8N2A8,Q9UIV1,Q5TA45,Q9UQ84,O15091 5 +Endonuclease activity 0.4354592932148856 0.7531766692280168 0.4513437572633196 1.0 1.0 30 Q8N2A8,Q5TA45,Q9UQ84,O15091,Q9UPY3,P51530,Q15631 7 +D1 dopamine receptor binding 0.6257803438865746 0.7503034617335212 0.4530719581791727 1.0 1.0 3 Q15334 1 +Poly purine tract binding 0.4926597084144206 0.7474716172774182 0.4547789292184858 1.0 1.0 14 O14979,P31483,Q6PJT7,Q71RC2,P11940,Q06787 6 +Vitamin binding 0.3377648141874968 0.7444877553498381 0.4565814462644511 1.0 1.0 42 P13674,Q32P28,O94788,P09455 4 +Phosphatidylinositol 3 phosphate binding 0.5289568378049421 0.7399162608082918 0.4593508070506509 1.0 1.0 5 O60493,Q5MNZ6,Q96L92 3 +5 3 dna helicase activity 0.5452995886857515 0.7310547785090088 0.4647456944303871 1.0 1.0 4 P51530 1 +Flavin adenine dinucleotide binding 0.4577467847514357 0.7260407412598574 0.4678137950067644 1.0 1.0 25 P11310,Q15392,O95831,Q14534 4 +Protein kinase a binding 0.4881069971861952 0.7206608716988078 0.4711181920090026 1.0 1.0 13 P35241,Q9H3P7,P41240,P10644,P49840,Q92667,Q96M27 7 +Nf kappab binding 0.4851698236396382 0.7165015297533383 0.4736817232609325 1.0 1.0 15 Q9NWT6,Q13547,O95999,Q86UE4,Q96JB5,P09525,P60900 7 +Eukaryotic initiation factor 4e binding 0.6154369262155779 0.7131171979985595 0.4757732382401873 1.0 1.0 3 Q6PKG0,Q04637 2 +Cytokine activity 0.4833470738369294 0.7100192263992269 0.4776922135757093 1.0 1.0 6 Q92520 1 +Camp binding 0.612583348316166 0.7029391208337041 0.4820936898774555 1.0 1.0 3 Q9Y4G8 1 +Inorganic molecular entity transmembrane transporter activity 0.3651531299915903 0.6853630547483304 0.4931148514782975 1.0 1.0 84 Q6N075,P20020,P00846,Q7KZN9,Q93050,Q96ES6,Q6P4Q7,P00403,Q8NE86,Q9HC07,P05026,Q96QD8,Q96S66,P21281,P23634,P20674,Q9NW15 17 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.8167912984364164 0.6844427174278496 0.4936956494100495 1.0 1.0 2 P30519 1 +Atpase binding 0.4295431671606304 0.6768909429258514 0.4984751510145466 1.0 1.0 29 Q86TM6,Q8IXB1,P35241,Q9BUN8,Q93050,Q8NFQ8,Q92542,P05026,P11233,P36543 10 +Copper ion binding 0.4783490123144764 0.6715348122585104 0.5018798901252324 1.0 1.0 12 O60888 1 +Integrin binding 0.4758233239878532 0.6703088978936114 0.5026608961078289 1.0 1.0 15 Q03001 1 +Vinculin binding 0.4740385777513746 0.6688217422058284 0.5036091956051818 1.0 1.0 6 P46939,O60504 2 +Phosphatidylglycerol binding 0.5266656937437274 0.6594321950871804 0.5096182736950674 1.0 1.0 4 Q9UJZ1 1 +Structural constituent of cytoskeleton 0.41378732696855 0.6505373822788184 0.515345163000219 1.0 1.0 31 O60504,P09493,P08670,P04350,Q01082,Q13509,Q16204,Q16352,Q9BUF5,Q96RT1 10 +Protein kinase b binding 0.8055744391570372 0.6488020636161244 0.5164663234493179 1.0 1.0 2 O95999 1 +Zinc ion transmembrane transporter activity 0.8052345343303886 0.6477314224592158 0.5171586769710099 1.0 1.0 2 Q8TAD4 1 +Cyclin binding 0.4698477839587648 0.6326952110958755 0.5269326977563495 1.0 1.0 10 P24941,O14976,Q9BWF3 3 +Epidermal growth factor receptor binding 0.5020419364309207 0.631636131093701 0.527624671345698 1.0 1.0 5 P62993 1 +Vascular endothelial growth factor receptor binding 0.799116247450715 0.6285581671675868 0.5296383546123171 1.0 1.0 2 Q9H2J4 1 +Sequence specific single stranded dna binding 0.4646614576562417 0.6278346109861257 0.5301122902267374 1.0 1.0 6 Q92878,P15927 2 +Glycolipid binding 0.4668985234078657 0.6259602559363076 0.5313410102416722 1.0 1.0 8 Q92643 1 +Nitric oxide synthase binding 0.590615436926232 0.6258998415744196 0.5313806384537405 1.0 1.0 3 P0DP25,P23634 2 +Phosphatidylserine binding 0.4669067303787511 0.6220360164053296 0.5339181856622184 1.0 1.0 9 Q8WTV0 1 +Calcium dependent phospholipid binding 0.4663144291306811 0.6152685515463663 0.5383773826180671 1.0 1.0 11 P09525 1 +O acyltransferase activity 0.4663122089951324 0.6152583896095701 0.538384092511921 1.0 1.0 11 P35610,Q6UWP7,P23786 3 +Aromatic amino acid transmembrane transporter activity 0.7946974847042841 0.6148295402709955 0.5386672985743006 1.0 1.0 2 P08195 1 +L ornithine transmembrane transporter activity 0.7946974847042738 0.6148295402709639 0.5386672985743215 1.0 1.0 2 Q9Y619 1 +Ribosomal large subunit binding 0.463076691039702 0.6144211333104594 0.5389370742061257 1.0 1.0 7 P98179 1 +Acyltransferase activity 0.3148606178340016 0.6086299479448002 0.5427697493336834 1.0 1.0 52 O00330,Q6UWP7,P23786,Q96QD8,Q15102 5 +Active ion transmembrane transporter activity 0.303520807394024 0.606493087387214 0.5441873712362155 1.0 1.0 44 P20020,Q15043,P08195,Q7KZN9,Q96ES6,P00403,P21281,Q96QD8,P05026,P36543,P20674,P23634 12 +Protein c terminus binding 0.3063387015288422 0.5657952895632129 0.5715329489642649 1.0 1.0 49 Q9NP79,Q12965,Q03001,Q13257,P05026,P18074,Q9UQB8,Q15334 8 +Poly a binding 0.4544414657742354 0.5614652958119469 0.5744803820755369 1.0 1.0 11 O14979,P31483,Q6PJT7,Q71RC2,P11940 5 +Metalloexopeptidase activity 0.4449580665477018 0.5609141182438376 0.5748560849928115 1.0 1.0 20 P55786 1 +Cargo receptor activity 0.4505541094078894 0.5498105370426654 0.5824493306608058 1.0 1.0 9 Q5JRA6,O15260,Q8WTV0 3 +Snrnp binding 0.4462972346179156 0.5493214216250096 0.5827848889726579 1.0 1.0 6 P08579,Q8WWY3,P62316 3 +Channel inhibitor activity 0.4454938109619333 0.5459460881392019 0.5851029963806242 1.0 1.0 6 P62942,Q9UKS6 2 +Double stranded telomeric dna binding 0.4791389234643747 0.5429292676671553 0.5871785037536945 1.0 1.0 5 Q92878,Q00577 2 +Single stranded dna helicase activity 0.4472113693075786 0.5298579955301597 0.5962103912265164 1.0 1.0 14 Q96S55,Q14566,P33991,P51530 4 +Atpase coupled cation transmembrane transporter activity 0.4425597428689614 0.5210411546110011 0.6023381024552106 1.0 1.0 17 P20020,P05026,P21281,P36543,P23634 5 +Mutlalpha complex binding 0.5583134988099392 0.5176536019052872 0.604699976034234 1.0 1.0 3 P12004,P43246 2 +Mismatch repair complex binding 0.5583134988099392 0.5176536019052872 0.604699976034234 1.0 1.0 3 P12004,P43246 2 +Acetylgalactosaminyltransferase activity 0.5575446846806056 0.5151621480678524 0.6064397171559968 1.0 1.0 3 Q10472 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.5575446846806056 0.5151621480678524 0.6064397171559968 1.0 1.0 3 Q10472 1 +Channel regulator activity 0.4431525142216542 0.5139354299651331 0.6072971355835488 1.0 1.0 15 P62942,O15400,Q9UKS6,O43768 4 +Protein demethylase activity 0.4864923999515761 0.5122917850186365 0.6084468137884067 1.0 1.0 4 Q8NB78 1 +Hyaluronic acid binding 0.7528891910265052 0.4904624302337614 0.6238067088425723 1.0 1.0 2 Q07021 1 +Metallopeptidase activity 0.3097470102397197 0.4882846904754983 0.6253482039386822 1.0 1.0 42 P55786,Q9NZ08 2 +Translation initiation factor activity 0.3635836563778175 0.4834784857632931 0.6287560320974483 1.0 1.0 35 P55010,P41214,P23588,O75822,Q15056 5 +Exopeptidase activity 0.3822115324096919 0.4830629061302876 0.6290510711151063 1.0 1.0 32 P55786,P42785 2 +Gamma tubulin binding 0.4603427046046481 0.4731256810713536 0.6361235158430607 1.0 1.0 5 Q9BSJ2 1 +Toxic substance binding 0.7454112848402332 0.4693919083339747 0.638789531114359 1.0 1.0 2 P34913 1 +Ion transmembrane transporter activity 0.3687320294765792 0.4676154108316898 0.640059642288969 1.0 1.0 106 P00846,O43772,Q9HC07,Q96QD8,Q96S66,P20674,Q9NW15,Q9H2D1,Q96ES6,P05026,P21281,Q14847,Q6N075,Q70HW3,Q93050,P00403,Q9BQT8,P20020,Q7KZN9,Q9Y619,Q6P4Q7,Q8NE86 22 +Passive transmembrane transporter activity 0.3466958022689097 0.4621402599340139 0.6439807406310538 1.0 1.0 37 Q8NE86,P00846,Q96S66 3 +Cardiolipin binding 0.5371822397965034 0.4508183043411031 0.6521205077089576 1.0 1.0 3 Q9UJZ1 1 +Phosphatase binding 0.2872925890215042 0.4493778468426794 0.6531591093266091 1.0 1.0 44 P42224,P35269,P78318,P15927,Q9NX63,Q8NFC6,Q9UQ13,P41240,O43768,P62993,O60493,O43815,Q05397,P23634,Q15334 15 +Kinetochore binding 0.7379333786539798 0.4487166249281368 0.6536360902187934 1.0 1.0 2 Q7Z460 1 +Scavenger receptor activity 0.4518331024212663 0.4425631671400262 0.6580817313288141 1.0 1.0 5 Q8WTV0 1 +Atpase coupled ion transmembrane transporter activity 0.4222849577082331 0.4363674737584416 0.6625701340976475 1.0 1.0 8 P36543,P21281 2 +Pyrophosphate hydrolysis driven proton transmembrane transporter activity 0.422284957708233 0.436367473758441 0.662570134097648 1.0 1.0 8 P36543,P21281 2 +Endopeptidase activity 0.311410342933078 0.4350703052704748 0.6635113967273232 1.0 1.0 63 Q9NZ08,Q5JRX3,P28070,Q9H300,O43847,Q92643,P28072,Q9Y4E8,Q92542,P49721,P28074,Q86UV5,Q4J6C6 13 +Snare binding 0.4020185434760009 0.431750828657692 0.6659225207505415 1.0 1.0 26 A2RRP1,Q6ZWJ1,O75150,Q08379,O60499,O15400 6 +Dna polymerase activity 0.4197826844268044 0.4263111258874041 0.6698811518090184 1.0 1.0 8 Q9NRG0 1 +Acyl coa binding 0.4227744996891106 0.4218309548962706 0.6731484096460014 1.0 1.0 12 P35610 1 +Fatty acid derivative binding 0.4227744996891106 0.4218309548962706 0.6731484096460014 1.0 1.0 12 P35610 1 +Cis trans isomerase activity 0.4058209872035306 0.4157972830228872 0.6775583471726343 1.0 1.0 24 Q96BP3,Q96AY3,Q9Y680,P62942,Q9NWM8 5 +Regulatory rna binding 0.4181159366560637 0.4121892041031764 0.6802007494858939 1.0 1.0 18 Q06787,Q9UPY3,P67809 3 +Rna polymerase ii core promoter sequence specific dna binding 0.4565064320983473 0.4110088202604844 0.681066067149521 1.0 1.0 4 Q13547 1 +Four way junction dna binding 0.4409663150731687 0.4045861669115358 0.6857817283661414 1.0 1.0 5 P26583,P52701,O15347,P43246 4 +Protein phosphatase binding 0.3239892307722097 0.4028171410245927 0.6870827503203158 1.0 1.0 39 P42224,P35269,P78318,P15927,Q8NFC6,Q9UQ13,P41240,O43768,P62993,O60493,O43815,Q05397,P23634,Q15334 14 +Galactosyltransferase activity 0.718218898708365 0.396217005970447 0.6919449468057932 1.0 1.0 2 Q8NBJ5 1 +Signaling receptor complex adaptor activity 0.4315876060298438 0.3728337749288738 0.709272163578452 1.0 1.0 5 O60271 1 +Rna polymerase ii ctd heptapeptide repeat phosphatase activity 0.7080217539089008 0.3702726474898802 0.7111793519195984 1.0 1.0 2 Q05D32 1 +Dynein heavy chain binding 0.7059823249490145 0.3651874600275395 0.7149714783073664 1.0 1.0 2 Q9Y6G9 1 +Tau protein binding 0.407625459666941 0.3647188020441722 0.7153213220136807 1.0 1.0 18 Q13526,Q00535,Q14203,P54652,P49840,O75116,P10909,P78559 8 +Ephrin receptor binding 0.4283718778114072 0.3621783999010496 0.7172187198047013 1.0 1.0 5 P62993,Q15375,Q00535 3 +Proline rich region binding 0.395941727241139 0.3502253672482129 0.7261695705517239 1.0 1.0 6 O00213,Q9UQB8,P41240 3 +Cadherin binding involved in cell cell adhesion 0.4043155082285604 0.3496800099781177 0.7265788574265828 1.0 1.0 11 Q9UQB8 1 +Single stranded dna endodeoxyribonuclease activity 0.6991842284160388 0.3484928385398087 0.727470091181341 1.0 1.0 2 Q92878 1 +Cyclic nucleotide binding 0.4364584018817241 0.3484502308197506 0.7275020845259732 1.0 1.0 4 Q9Y4G8 1 +Sh3 domain binding 0.4051222511860353 0.3472123499204148 0.7284317934316271 1.0 1.0 13 Q96PU8,Q16204,Q96D71,Q9Y5K6,P62993 5 +Phosphatidylinositol 3 5 bisphosphate binding 0.3931832055758669 0.3401843112850067 0.7337177321813504 1.0 1.0 6 O60493,Q5MNZ6,Q92538 3 +Basal transcription machinery binding 0.3872167048054517 0.3367385336296836 0.7363140124520715 1.0 1.0 25 P35269,Q5VT52,Q9H7B4,Q5BKZ1 4 +Primary active transmembrane transporter activity 0.2862948373201507 0.3286484245978214 0.7424214417935682 1.0 1.0 53 P20020,O43676,Q7KZN9,P00403,O96000,P21281,P05026,P03886,P20674,P23634 10 +Acidic amino acid transmembrane transporter activity 0.4285714285714327 0.325127414731156 0.7450846411679906 1.0 1.0 4 O75746,Q15758,Q9H936 3 +L aspartate transmembrane transporter activity 0.4285714285714327 0.325127414731156 0.7450846411679906 1.0 1.0 4 O75746,Q15758,Q9H936 3 +Protein carrier chaperone 0.3973560319567446 0.319060863804446 0.7496803600068243 1.0 1.0 12 Q9NPA0,P10909,P40855,Q9Y5J7 4 +Protein kinase a catalytic subunit binding 0.3863172226004046 0.3156539643150333 0.752265172542687 1.0 1.0 6 P15311,P49841,P41240,P10644,P49840 5 +Proton transmembrane transporter activity 0.3049607742259723 0.3154659653762168 0.7524078884395049 1.0 1.0 40 P00846,Q7KZN9,Q93050,Q96ES6,P00403,P21281 6 +Serine hydrolase activity 0.3935762590353665 0.3137539218958026 0.7537079433518392 1.0 1.0 20 P42785,Q4J6C6 2 +P type calcium transporter activity 0.4244420020019523 0.31322500755811 0.7541097203889962 1.0 1.0 4 P20020 1 +Dna insertion or deletion binding 0.4200680272108872 0.300856147797769 0.7635241908840023 1.0 1.0 4 P12004,P43246,P52701 3 +Mismatched dna binding 0.4200680272108872 0.300856147797769 0.7635241908840023 1.0 1.0 4 P12004,P43246,P52701 3 +Oxidized dna binding 0.4200680272108766 0.3008561477977396 0.7635241908840247 1.0 1.0 4 P23396,P43246,P52701 3 +Cyclin dependent protein kinase activity 0.4082569688667921 0.2984257311071008 0.765378252679191 1.0 1.0 5 P24941 1 +Protein heterodimerization activity 0.289015819733193 0.2946213407114798 0.7682831578918139 1.0 1.0 58 Q8NAN2,Q9NRG0,P09493,O14920,Q9NRF9,P05026,Q06787,Q15102 8 +Anaphase promoting complex binding 0.6743711760707046 0.291038196928104 0.771022106393844 1.0 1.0 2 Q16763 1 +Protein disulfide isomerase activity 0.3862162486457902 0.2863175512858625 0.7746349165913249 1.0 1.0 10 Q9BS26,Q96JJ7,Q92643,P30040 4 +Long chain acyl coa dehydrogenase activity 0.4102040816326528 0.2738909240647481 0.7841684465394272 1.0 1.0 4 Q9NZ01,Q709F0,P49748 3 +Calmodulin binding 0.3061745936501061 0.2718200787635987 0.7857603656904735 1.0 1.0 39 P29966,P20020,Q01844,Q01082,Q12965,P49006,Q13813,Q7Z406,P35611,P23634,P49137 11 +Atp dependent activity acting on dna 0.2713189506944217 0.2686666792247199 0.7881861953922422 1.0 1.0 47 Q96S55,P35250,Q92878,P13984,Q14566,P33991,P51530,P18074,Q14527 9 +Ubiquitin like protein ligase activity 0.2973473325087259 0.2592663918299215 0.795429708458085 1.0 1.0 40 Q9Y508,Q86TM6,Q96MF7,O75150,Q5VTR2,Q9H270,Q96T88,P19474,Q14527,Q15386 10 +Single stranded dna binding 0.2764146395798896 0.2551364858891209 0.7986176847546975 1.0 1.0 52 Q96AE4,P15927,Q92878,Q8NFH5,Q9Y2W2,Q14566,P53999,P52434,P33991,Q15631,Q9H1E3,Q9P2K5,P67809 13 +Snap receptor activity 0.378424195485008 0.2533777758611298 0.7999762997352629 1.0 1.0 11 O15400 1 +Amide binding 0.3382231127411665 0.247072832030303 0.8048518589279143 1.0 1.0 102 P01889,P55786,P07602,Q9NQX7,P35610,Q15392,Q9NZ08,P52292,P62942,P10909,Q8WTV0,O00264,Q9UIQ6,Q96AY3,Q9Y680,P55899,Q96BP3,Q9H3P7,O15212,P04439 20 +Protein phosphatase 2a binding 0.372925152633465 0.2461927393423632 0.8055330357892367 1.0 1.0 9 P42224,Q8NFC6,P78318,O43768 4 +Acylglycerol o acyltransferase activity 0.3682035112317491 0.2456516741104361 0.805951884431146 1.0 1.0 7 Q6UWP7 1 +Nuclease activity 0.284456567331547 0.2451504585625921 0.8063399343699569 1.0 1.0 59 Q8N2A8,Q9UIV1,Q5TA45,Q9BQ61,Q9UQ84,O15091,Q9UPY3,P51530,Q15631 9 +Udp glucosyltransferase activity 0.3878612592723659 0.2393692060744481 0.8108193060022977 1.0 1.0 5 P13807,Q9NYU2 2 +Mirna binding 0.3776920412966854 0.2381714940151277 0.8117480854938885 1.0 1.0 15 Q06787,P67809 2 +Gtpase activating protein binding 0.3840142450756074 0.2289124862712953 0.8189369355859393 1.0 1.0 5 P08754,Q13526 2 +Beta tubulin binding 0.374562319623768 0.2267219594005645 0.8206399505855924 1.0 1.0 15 P50402,Q66K74,Q9UQE7,Q9H6U6 4 +Alpha tubulin binding 0.4505270316219055 0.2215061353377259 0.8246983599367359 1.0 1.0 3 Q9HC35,Q92598 2 +Oxidoreduction driven active transmembrane transporter activity 0.353368492279956 0.2177908455806397 0.827592077535835 1.0 1.0 28 P00403,O96000,P03886 3 +Deoxyribonuclease activity 0.371784704087373 0.2154621040667487 0.8294070547547334 1.0 1.0 17 Q66K74,Q92878,Q9UQ84,Q9UPY3,P51530 5 +Protein disaggregase activity 0.3816326530612231 0.2035021485341714 0.8387425665300627 1.0 1.0 4 P0DMV9,P11142,Q9UN37 3 +Chemoattractant activity 0.4406664399864103 0.2008938603246936 0.8407815685998874 1.0 1.0 3 P26583,P14174 2 +Ubiquitin like protein conjugating enzyme binding 0.3618008742274048 0.1975596552561133 0.8433896030222476 1.0 1.0 11 O75150,Q9Y679,Q92564 3 +Translation repressor activity 0.353414986121661 0.1914786889957485 0.8481505753527145 1.0 1.0 8 Q14011 1 +Protein membrane adaptor activity 0.3522672703387037 0.1806708242194678 0.8566259607802649 1.0 1.0 9 Q9UH99,P12270 2 +Acetyltransferase activity 0.3505182461581657 0.1779799441902365 0.8587387264795954 1.0 1.0 26 Q15102,Q96QD8 2 +Amide transmembrane transporter activity 0.3670068027210823 0.1721753098217671 0.8632997079097853 1.0 1.0 4 Q03519,Q9H2D1,O00400 3 +Dna helicase activity 0.3193310433920767 0.170580990011162 0.8645532465997277 1.0 1.0 34 Q96S55,P35250,P13984,Q14566,P33991,P51530,P18074 7 +Molecular function inhibitor activity 0.3486011102298001 0.1698765762717557 0.8651072027816 1.0 1.0 9 P62942,Q9UKS6,O43768 3 +Electron transfer activity 0.2603544844088897 0.1680920644782533 0.8665108521558471 1.0 1.0 48 O43676,P00403,O96000,O15460,P03886 5 +Protease binding 0.3453599993774208 0.1670783508520797 0.8673084000826377 1.0 1.0 27 Q86TM6,Q9BUN8 2 +Atp dependent protein binding 0.4219653179190747 0.1652420917970454 0.8687534361493616 1.0 1.0 3 Q13838,Q9UBE0 2 +Phosphatase inhibitor activity 0.3365169746247156 0.1603628257771598 0.8725952713304481 1.0 1.0 6 Q01105,O43768 2 +Active transmembrane transporter activity 0.2915169755484606 0.1586010430739005 0.8739832069447317 1.0 1.0 73 O43676,Q96ES6,P00403,O96000,Q8NE86,P05026,Q96QD8,P03886 8 +Insulin like growth factor receptor binding 0.5992522093813798 0.1535461281226872 0.8779676165786718 1.0 1.0 2 P61981 1 +Organic acid transmembrane transporter activity 0.3539741999994926 0.1528402260052286 0.8785242746280064 1.0 1.0 19 Q9H2D1,Q9Y619,Q96QD8,P08195,Q9BQT8,P30825 6 +Chaperone binding 0.2570182857986672 0.1525708577880467 0.8787367080081161 1.0 1.0 47 Q86TM6,Q8IXB1,P01889,O14976,O15212,Q9Y5J7,Q9Y4L1,O95429,O95817,P10909,Q9UL15 11 +Rna methyltransferase activity 0.352264961250463 0.1508655470316388 0.8800817788449442 1.0 1.0 15 Q96FX7,Q08J23 2 +Phosphatidylinositol binding 0.2628514097729879 0.1465363181661801 0.8834980215915547 1.0 1.0 52 O14964,Q9NV70,Q9H6U6,Q92783,Q9BZF1,Q12965,Q92643,Q5MNZ6,O60493,Q96L92,Q8WTV0 11 +Ubiquitin ubiquitin ligase activity 0.3308373042886369 0.1454829393936975 0.8843295848320634 1.0 1.0 6 Q9UKV5,Q9UNE7,Q9UMS4,O95155,P61086 5 +Methyl cpg binding 0.3386712095400304 0.1419687775339669 0.8871046677645409 1.0 1.0 9 O14744,Q96T88,Q9BQA1,Q9Y3Y2,P84090,O95983,P51608,P26358 8 +Gtpase inhibitor activity 0.3292738074990911 0.1414967259657147 0.8874775463230353 1.0 1.0 6 Q13098,O00410,Q13576 3 +Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.3437384851157261 0.1405066898183404 0.888259667214665 1.0 1.0 25 Q9UQ84 1 +Copper ion transmembrane transporter activity 0.589734874235221 0.1402147845357756 0.888490290931397 1.0 1.0 2 Q04656 1 +Oxidoreductase activity acting on nad p h 0.3385784525137458 0.1381344363183677 0.8901341703972592 1.0 1.0 27 O95831,O96000,P03886 3 +Carbohydrate binding 0.2657822548842827 0.1368229077489892 0.8911707761622882 1.0 1.0 42 Q9NPA0,P13674,Q9BWS9,Q10472,O15460,Q32P28 6 +Phosphoric diester hydrolase activity 0.3426370690241775 0.1342176034423646 0.8932305063237489 1.0 1.0 12 Q8N2A8,P22413,P09601 3 +Secondary active transmembrane transporter activity 0.345644092540022 0.1274159279238863 0.8986112103270378 1.0 1.0 21 Q8NE86,Q96QD8 2 +Virion binding 0.5788579197824679 0.1260968941925075 0.8996552259240451 1.0 1.0 2 Q99816 1 +Nucleocytoplasmic carrier activity 0.3456770047951418 0.1255954050583616 0.9000522003859068 1.0 1.0 20 Q9UI26,Q9C0E2,P52292 3 +Signaling receptor regulator activity 0.3445099863177223 0.1242225412631204 0.901139075122556 1.0 1.0 16 Q9UMX5 1 +Protein arginine n methyltransferase activity 0.3382102756039428 0.122604838613462 0.9024200226960116 1.0 1.0 5 Q86X55,Q7L592,O60678,O14744 4 +Transcription coactivator activity 0.2887872764478966 0.1197371695552352 0.9046913551162652 1.0 1.0 75 O95999,P61457,Q8TAQ2,Q5VTR2,Q96TA1,Q9H1E3,Q9Y2W1,Q96PK6,Q86UE4,P53999,P19474,Q13503,P17096,P35637,O60885,Q13330,Q13951 17 +Camp dependent protein kinase regulator activity 0.3859231553893256 0.1094281343101572 0.9128629197832084 1.0 1.0 3 P54619,P10644 2 +Glucocorticoid receptor binding 0.5594833446635019 0.1038352424811394 0.9173000981682686 1.0 1.0 2 Q04917 1 +Solute cation antiporter activity 0.3801428085685147 0.1020388513012156 0.9187258371298872 1.0 1.0 3 P08195,O95202 2 +Chemokine receptor binding 0.3258503401360594 0.101860570341288 0.918867347429996 1.0 1.0 4 P42224,P48681,O43776 3 +Pre mrna intronic binding 0.3267457538803138 0.1014875791800047 0.9191634170282584 1.0 1.0 5 Q9BWF3 1 +Wd40 repeat domain binding 0.3238095238095277 0.0990549463948069 0.9210946436604122 1.0 1.0 4 Q96K76,P40227,Q99459 3 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.5523453433038794 0.0965374522497917 0.9230937302227478 1.0 1.0 2 O00625 1 +Exonuclease activity 0.3081262342879461 0.0921416806477789 0.9265854729202035 1.0 1.0 33 Q9UQ84,Q9UIV1 2 +Tau protein kinase activity 0.3073519400953086 0.0907162861584661 0.9277180295075949 1.0 1.0 6 Q00535,P49841,P49840,O75116,Q13464 5 +Zinc ion binding 0.3441331695717265 0.0863469131307335 0.931190646419262 1.0 1.0 126 Q8N4Q0,Q8NCC3,Q96MF7,O95486,O75312,P55786,Q8TBF4,Q96T88,Q12874,Q03164,Q9Y5J9,P19474,O95251,Q14527,Q9NWT6,Q92696,Q9NZ08,Q9UPP1,Q8TAD4,Q9Y5J7,Q5JTZ9,Q8N8N7,Q15637,P46939,Q07864,Q8NB78,Q16629,Q5JRX3,Q8WXI9,Q96KQ7,Q99707,Q9UIQ6,Q5VUA4,Q9Y5L4,P62875,Q13330,Q9GZZ9,P22413,Q9NUD5,Q53GS9,Q7RTV0,Q9BWF3,P23193,Q99584 44 +Ether hydrolase activity 0.3154629298900747 0.0828806021799208 0.9339464781844596 1.0 1.0 5 P34913 1 +Epoxide hydrolase activity 0.3154629298900747 0.0828806021799208 0.9339464781844596 1.0 1.0 5 P34913 1 +Nuclear import signal receptor activity 0.3251368562030411 0.0824196193595089 0.9343130351331664 1.0 1.0 13 P52292,Q9UI26 2 +Nucleoside monophosphate kinase activity 0.3092511922857912 0.0785828137016595 0.9373644579388076 1.0 1.0 8 Q00013,Q9UIJ7,Q9UDY2 3 +Calcium dependent protein kinase activity 0.3583815028901741 0.0779185248964126 0.9378928634740302 1.0 1.0 3 Q16513,P49137 2 +Heme transmembrane transporter activity 0.5282121006118372 0.0752692093539135 0.9400005193426344 1.0 1.0 2 O15173 1 +U4 snrna binding 0.2987329808170624 0.0734010462617268 0.9414869850466778 1.0 1.0 6 O43172 1 +Cell cell adhesion mediator activity 0.3251747562287447 0.0666834779074277 0.9468336877518452 1.0 1.0 17 Q9UQB8,P61026 2 +Clathrin light chain binding 0.5101971447994649 0.0625775768901469 0.9501028854637896 1.0 1.0 2 Q00610 1 +Molecular carrier activity 0.2881944487918011 0.0604957367245562 0.9517608112339256 1.0 1.0 36 Q9NPA0,Q9Y5L0,P52292,Q9C0E2,Q9Y5J7,Q9UI26,P40855,P10909 8 +Phospholipase c activity 0.5064581917063313 0.0602575483697751 0.9519505119672872 1.0 1.0 2 P19174 1 +Double stranded rna adenosine deaminase activity 0.4959211420802267 0.0542616680203722 0.9567266890256892 1.0 1.0 2 P55265 1 +Protein phosphatase activator activity 0.492182188987093 0.0523186326071518 0.9582748069746994 1.0 1.0 2 P0DP25 1 +Metalloendopeptidase activity 0.3157482391890812 0.0504770075324231 0.9597422713741116 1.0 1.0 15 Q96E52,Q5JRX3,O43847 3 +Ubiquitin like protein transferase activity 0.251620402818015 0.0480238816632115 0.9616972097475276 1.0 1.0 54 Q9Y508,Q86TM6,P61088,Q96MF7,O75150,Q5VTR2,Q9H270,Q96T88,Q9NT62,P19474,Q7Z7E8,Q14527,Q15386 13 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3193654174193622 0.0451776776698739 0.963965686718752 1.0 1.0 21 O96000,P03886 2 +Structural constituent of nuclear pore 0.3184613922139493 0.0446867282538347 0.964357012450253 1.0 1.0 19 Q8NFH5,P12270,Q5SRE5 3 +Sodium ion binding 0.4714479945615327 0.0431477316645456 0.9655837703382736 1.0 1.0 2 O00764 1 +Structural constituent of presynaptic active zone 0.4660095173351518 0.0411557190197835 0.9671717548433212 1.0 1.0 2 P56545 1 +Ubiquinone binding 0.4643099932019135 0.0405655490757839 0.9676422493922504 1.0 1.0 2 P21912 1 +Oxidoreductase activity acting on a sulfur group of donors 0.3163983417451078 0.0400487140166805 0.9680542892524828 1.0 1.0 24 O43396,Q8IXB1,O95881,Q9UHG3 4 +Tat protein binding 0.2968378102686153 0.037158220475551 0.970358850819756 1.0 1.0 3 P06748,P51532 2 +Microfilament motor activity 0.2898198772618291 0.0344139388999504 0.972547068421195 1.0 1.0 9 Q12965 1 +Chemokine binding 0.4405166553365164 0.0337610471185002 0.9730676981216556 1.0 1.0 2 P05556 1 +Phospholipid binding 0.2883457294066667 0.0323951729715414 0.9741569118800566 1.0 1.0 85 Q8NCC3,Q9H6U6,Q01082,Q9UKS6,P07602,O14964,Q9BZF1,Q9Y4G8,Q96L92,Q8WTV0,Q9UJZ1,Q92783,Q12965,Q92643,P50995,O15020,P09525,Q8NFH5,Q5MNZ6,O60493,Q9NV70 21 +Anion channel activity 0.2982626770144757 0.0297761714217012 0.9762455627893722 1.0 1.0 12 Q9NW15,Q96S66 2 +Anion transmembrane transporter activity 0.2423080410429282 0.0285214254175246 0.9772462799669984 1.0 1.0 43 Q6N075,Q9Y619,Q96QD8,Q96S66,Q9BQT8 5 +Rna polymerase ii c terminal domain binding 0.2257433719885377 0.0270088355508791 0.9784526868528034 1.0 1.0 4 O60885 1 +Leukotriene c4 synthase activity 0.3902107409925304 0.0261076160743675 0.9791715023855394 1.0 1.0 2 O14880 1 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.3103331067301216 0.0230523158275279 0.9816085420234164 1.0 1.0 2 P42771 1 +Transcription coregulator activity 0.3338923459098949 0.0186203883191853 0.985143938128404 1.0 1.0 126 Q01844,Q8TAQ2,Q96TA1,Q9NYF8,Q92804,P19474,Q9UPP1,Q9UIV1,P61457,P53999,Q15637,Q9H1E3,Q13951,Q07021,Q5VTR2,Q9Y2W1,Q96IZ0,P35637,O60885,Q96T58,Q13547,O95999,P80723,Q7Z4V5,Q86UE4,Q13503,Q9HCD5,P17096,Q13330,Q96PK6 30 +Cell adhesion mediator activity 0.3073891081876326 0.0176545378832317 0.9859144485024662 1.0 1.0 19 Q9UQB8,P61026 2 +Inorganic anion transmembrane transporter activity 0.3054174941810909 0.0160519422089535 0.98719295313057 1.0 1.0 18 P0CG08,Q6N075,Q9NW15,Q96S66 4 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.2699260909212005 0.0117094532175522 0.9906574215582638 1.0 1.0 8 Q7Z3T8,Q92538,O15294,Q13576 4 +Histone binding 0.2710318444187741 0.0091209045650042 0.9927226719684116 1.0 1.0 74 Q9H6U6,Q8TAQ2,P55209,Q96T88,Q03164,O95251,Q9UPP1,P45973,Q06787,Q8NB78,Q5VTR2,P83916,Q01105,O60885,O00213,P25440,P49321,P42224,Q8WWQ0,Q7Z4V5,Q9Y4E8,Q99733 22 +Mrna binding 0.368140471978813 0.0083414008717531 0.9933446022083356 1.0 1.0 160 O75153,Q9Y5S9,P52756,Q99729,Q09161,Q92804,Q07955,P31483,Q01085,Q9NQ29,P12270,O43432,P61978,O60306,O43390,Q08170,P51114,P62995,P51991,Q15637,O00267,P19338,P42766,Q06787,Q13243,P67809,P38159,Q07021,O75150,Q5VTR2,Q9UN86,Q9BWU0,Q12849,P35637,Q9NPI6,Q15631,Q96T58,Q8N684,Q96AE4,Q8WVV9,Q96PU8,Q96PK6,Q13247,Q9BWF3,Q71RC2,P11940,Q14011,P22626,Q9P2K5 49 +Mitogen activated protein kinase binding 0.2602554224074466 0.0068660015132751 0.9945217664406024 1.0 1.0 7 Q96JB5,P12270 2 +Protein macromolecule adaptor activity 0.2805009521534262 0.0063721886738044 0.9949157634460636 1.0 1.0 82 Q99747,Q92542,P12270,O15400,O60271,Q92878,Q9H270,O94901,P05026,O14641,P45973,Q9UQB8,P18074,Q9UDY2,Q9UH99,Q9UN86,Q13620,Q8TD16,O60499,P62993,Q86VM9,P78559,P61962 23 +Rna cap binding 0.2726434436790348 0.0017435867761227 0.9986088197357984 1.0 1.0 10 O43432 1 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cdf806a0809836f3761ad7d15a1d4b860442945e --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Camp response element binding", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fructose transmembrane transporter activity", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Rage receptor binding", "Rdna binding", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATF7IP", "ATG3", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPIF1", "ATXN2L", "AUP1", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "C1orf50", "C20orf27", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CERS4", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ9", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCK", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENPP1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC6L", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC5", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGH", "GHDC", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOPC", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPCAL4", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "IST1", "ISYNA1", "ITGB1", "ITM2C", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LYAR", "LYPLA1", "LYPLA2", "LZTFL1", "MACF1", "MAD2L1", "MAN1A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED21", "MED24", "METAP2", "METTL13", "MFN2", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL33", "MRPL37", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL55", "MRPL58", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXNAD1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGU", "PIH1D1", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLPBP", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POGLUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM2", "PUM3", "PURA", "PURB", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDX", "RECQL", "REEP4", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNF114", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCB", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "SYVN1", "TAB1", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TES", "TFAM", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM106B", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM38B", "TMEM43", "TMEM70", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", 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3.783980582524272 16.274271844660195 0.5436026262586074 0.5269340846045785 2.1360147265981855 1.9458739529228473 0.8481478897769046 0.3232524565257521 0.0112943240362007 0.0412914524019695 0.1923105654227066 0.4841018564616677 +Head tremor 1 13 1.9802531743217209 0.0476750875547868 2.9563106796116503 13.3252427184466 0.4342055003305567 0.5012574626709954 2.027249794357098 1.0932465631703912 0.9190385225705504 0.3021636126820415 0.1157751708195439 0.0246740936940832 0.123579290468326 0.1204887281128287 +Visual loss 9 50 1.972835950529024 0.0485142558033595 12.189320388349516 49.779126213592235 0.7709512625515322 0.4025114627500821 4.5744204921606055 5.175300864908489 1.242827263568942 0.3662286004483653 0.0408125099476932 0.0670588556929843 0.0142430684063797 0.0796125915144056 +Parathyroid adenoma 1 5 1.9638726112999028 0.0495448667942022 1.953883495145631 5.334951456310679 0.1934336223413519 0.3476850576062903 1.202872559415007 0.967652422740595 1.374245033457798 0.3050616837572409 0.0012601973854463 0.0049445172385496 0.0282524409787331 0.0978216105640502 +Abnormality of the parathyroid morphology 1 5 1.9638726112999028 0.0495448667942022 1.9951456310679612 5.54126213592233 0.174968201326553 0.3509598237346392 1.2385301843824976 1.1216087437262623 1.374717808134014 0.307204091695738 0.0030581061915538 0.0117676307173903 0.0635022977163126 0.2004310968060411 +Neoplasm of the parathyroid gland 1 5 1.9638726112999028 0.0495448667942022 1.953883495145631 5.334951456310679 0.1934336223413519 0.3476850576062903 1.202872559415007 0.967652422740595 1.374245033457798 0.3050616837572409 0.0020655426456597 0.0080257871552124 0.0445602183527292 0.1472320281277068 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fb5ca0ce8d929789d3ccc205ad66944a13170195 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 4543, + "title": "Average number of proteins per term", + "value": 21.893682588597844 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b9297f5a648994299478314aa4bc6b3d17499dd7 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cdbc5bfeb01b05dcea58c9d75d72cbfd041f7aa2 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1403 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Anarthria 0.874999870399354 2.4821276683797495 0.0130600474121893 1.0 1.0 6 Q99720 1 +Oromandibular dystonia 0.8681378939402569 2.4531484945398985 0.0141611866230544 1.0 1.0 6 Q99720 1 +Mitochondrial inheritance 0.9690170823935916 2.4392904002092624 0.0147161368924275 1.0 1.0 4 P00846,P03886 2 +Optic disc pallor 0.4827313822656833 2.382370904786768 0.0172015620579257 1.0 1.0 47 P00846,Q8WWY3,Q96CU9,O96000,O60313,Q96S66,Q9BUK6,P03886,O43676,Q9UG56,O95831,Q9NPL8,Q9H0B6,Q9NX14,O43837,O00429,P04439,O43172,Q8IUX1,Q6P4Q7,O95140,O75489 22 +Lacticaciduria 0.918402044332109 2.371856734594919 0.0176989519359445 1.0 1.0 5 P03886,O96000,P00846 3 +Mitochondrial respiratory chain defects 0.9169883883946084 2.366264606380736 0.0179685967633316 1.0 1.0 5 P03886,P00846 2 +Hyperventilation 0.8468854320347734 2.362764179839267 0.0181392079051692 1.0 1.0 6 P00846 1 +Abnormal urine ph 0.4868166743257518 2.3071394939736156 0.0210470448653885 1.0 1.0 43 P00846,O43772,P23786,P11310,O96000,P48735,Q9BQT8,P03886 8 +Respiratory distress 0.4810005576467743 2.304590409660968 0.0211895235930119 1.0 1.0 51 Q8TCJ2,P00846,Q13724,P04350,O95831,P23786,Q9Y619,P07602,P49419,P21281,O60524,P03886 12 +Cerebral palsy 0.8222972176939104 2.291630789013627 0.021926957261048 1.0 1.0 9 P48735,P61457 2 +Psychotic mentation 0.922777988787434 2.2616510828746907 0.0237189692477692 1.0 1.0 4 P03886 1 +Retinal telangiectasia 0.8902962925027336 2.260010981686412 0.0238205692796551 1.0 1.0 5 P00846 1 +Mixed demyelinating and axonal polyneuropathy 0.9205024080557376 2.25281960285208 0.0242705256761817 1.0 1.0 4 P03886 1 +Neck flexor weakness 0.9193146563894304 2.2482066599917623 0.0245630152060813 1.0 1.0 4 Q99720 1 +Arm dystonia 0.9150518953607768 2.2316324822957103 0.0256392629802144 1.0 1.0 4 Q99720 1 +Head titubation 0.8132313048748459 2.226826419972232 0.0259588769358312 1.0 1.0 7 Q99720 1 +Hypothermia 0.7966512347206368 2.2077247683495265 0.0272634651662704 1.0 1.0 11 O43772,P00846 2 +Upper limb spasticity 0.8051213436946238 2.191158175616048 0.0284403480482966 1.0 1.0 7 Q99720,Q12768,P35637 3 +Stroke like episode 0.8069332238535742 2.1902621050360014 0.0285052334392335 1.0 1.0 6 P00403,P03886 2 +Hemianopia 0.8045446381961361 2.1886164341963714 0.0286247303241142 1.0 1.0 7 P03886 1 +Hypoketotic hypoglycemia 0.798060239401808 2.17044397119794 0.0299732287879896 1.0 1.0 8 O43772,P31751,P23786 3 +Vitiligo 0.7969170598922908 2.154932454079203 0.031167120296794 1.0 1.0 7 P00403,P03886 2 +Segmental peripheral demyelination remyelination 0.8629065952706911 2.149673855928744 0.0315810218519152 1.0 1.0 5 P00846 1 +Bulbar signs 0.7725256266794402 2.1334885520078104 0.0328846697768667 1.0 1.0 13 Q99720,P00846,P07602,P35637,P03886 5 +Centrocecal scotoma 0.8883119213702264 2.1270038889293414 0.0334197600715453 1.0 1.0 4 P00846 1 +Blurred vision 0.8561585485874476 2.12228873996401 0.0338134984640814 1.0 1.0 5 P03886,P00846 2 +Neonatal hypoglycemia 0.7841299510432967 2.1198574499373186 0.0340180686742837 1.0 1.0 9 O00330,O43772,P31751 3 +Unexplained fevers 0.8552687076016743 2.11867167664376 0.0341182235871939 1.0 1.0 5 Q9HC07 1 +Myoclonic spasms 0.8548841088380401 2.11710791986923 0.0342506896917078 1.0 1.0 5 P00846 1 +Abnormal upper motor neuron morphology 0.7859841935792731 2.116353102450396 0.034314787526976 1.0 1.0 8 Q99720 1 +Abnormality of krebs cycle metabolism 0.8518133496242302 2.1046132328785996 0.0353249887960189 1.0 1.0 5 P00846 1 +Mediastinal lymphadenopathy 0.8799319727891168 2.093982976398823 0.0362614967563801 1.0 1.0 4 P01889,O15460,Q01844 3 +Ventricular preexcitation 0.7830557882581344 2.093404489769264 0.0363130619758875 1.0 1.0 7 P03886,P00846 2 +Basal ganglia cysts 0.7829903266397498 2.093112955536802 0.0363390724694145 1.0 1.0 7 P00846 1 +Abnormal speech prosody 0.7789334665084409 2.084627266870013 0.0371031474334995 1.0 1.0 8 P00846 1 +Titubation 0.7682773441594296 2.0607278937959266 0.0393290069415914 1.0 1.0 10 Q99720,P35637 2 +Aortic dissection 0.8409725416550118 2.060373313188854 0.0393628661152629 1.0 1.0 5 P01889,O15460 2 +Polyphagia 0.7773280359049382 2.06026947470814 0.0393727864151109 1.0 1.0 6 Q4J6C6 1 +Abnormal morphology of the musculature of the neck 0.7572129180678724 2.060200856701946 0.0393793430609046 1.0 1.0 13 Q99720,P04350,P35637 3 +Retrocollis 0.9699091242941958 2.058666169674616 0.0395262291696516 1.0 1.0 3 Q99720 1 +Breast hypoplasia 0.8686916850285384 2.049520232927978 0.04041127144803 1.0 1.0 4 Q8WWQ0 1 +Abnormal circulating acetylcarnitine concentration 0.7725289215038382 2.0464077492295583 0.0407162702917736 1.0 1.0 7 O43772,P23786 2 +Vascular tortuosity 0.9629462557392294 2.032765372696604 0.0420762330985233 1.0 1.0 3 P00846 1 +Slow decrease in visual acuity 0.766963020109394 2.0305230385533823 0.0423034017827879 1.0 1.0 8 P00846 1 +Abnormal circulating citrulline concentration 0.8285600543173324 2.0094742160193975 0.0444868664362676 1.0 1.0 5 P03886,P00846 2 +Abnormal circulating non proteinogenic amino acid concentration 0.7622571485381495 2.0003280795552505 0.0454648488526538 1.0 1.0 7 P03886,P00846 2 +Chondrosarcoma 0.9510370622237364 1.9883279227090087 0.0467754345622415 1.0 1.0 3 O75874,P48735 2 +Abnormal head movements 0.7521917208242843 1.9860575062450232 0.0470269389401198 1.0 1.0 10 Q99720,P35637 2 +Abnormal corpus striatum morphology 0.7368758520246632 1.9824197792072356 0.0474322776736551 1.0 1.0 14 P00846 1 +Head tremor 0.7406351617282835 1.9802531743217209 0.0476750875547868 1.0 1.0 13 Q99720 1 +Visual loss 0.4457144721121627 1.9728359505290236 0.0485142558033595 1.0 1.0 50 P00846,A2RRP1,Q13509,P48449,P07602,P00403,O15460,P04439,P03886 9 +Parathyroid adenoma 0.8174924795891448 1.9638726112999028 0.0495448667942022 1.0 1.0 5 P48735 1 +Abnormality of the parathyroid morphology 0.8174924795891448 1.9638726112999028 0.0495448667942022 1.0 1.0 5 P48735 1 +Neoplasm of the parathyroid gland 0.8174924795891448 1.9638726112999028 0.0495448667942022 1.0 1.0 5 P48735 1 +Facial grimacing 0.9443611453065948 1.9633433286239936 0.0496062940227766 1.0 1.0 3 Q8WXI9 1 +Episodic vomiting 0.7431480302434886 1.9578409578192293 0.0502486777253301 1.0 1.0 11 P00403,P03886,P00846,P61978 4 +Pericarditis 0.8153441959142843 1.9549976198396608 0.0505833512049775 1.0 1.0 5 Q9NZ08,O15460 2 +Abnormal waist to hip ratio 0.7469506497941146 1.9394029997823847 0.0524522855460971 1.0 1.0 8 O00330,P22413,P31751 3 +Abnormal vascular physiology 0.4326378776644647 1.9193226797975955 0.0549435094850312 1.0 1.0 45 P35250,Q9NZ08,P22413,P01889,O95235,P00403,O96000,O15460,Q9NWM8,Q15056,P03886 11 +Low frustration tolerance 0.7402241353980841 1.9183648148027952 0.0550647692340229 1.0 1.0 9 Q03164 1 +Axial dystonia 0.932261144058372 1.9179261647551695 0.0551203740349981 1.0 1.0 3 Q99720 1 +Fluctuations in consciousness 0.7450229416079075 1.9163695738269604 0.0553180707961999 1.0 1.0 6 P03886 1 +Thick eyebrow 0.4306104164607605 1.9146080284153704 0.0555425105011684 1.0 1.0 44 Q96T58,Q8WWQ0,A2RRP1,Q9BSJ2,Q8TAQ2,Q01082,Q9Y2U8,O95831,Q03164,Q9UQE7,Q69YQ0,P21281,O60885,Q08J23 14 +Widened cerebral subarachnoid space 0.9265106838514628 1.8962831175080168 0.0579226174543776 1.0 1.0 3 P03886 1 +Action tremor 0.441056318961772 1.895710885193089 0.0579982851571765 1.0 1.0 52 Q99720,P00846,P04350,P07602,Q6PJG6,P35637,P03886 7 +Amyotrophic lateral sclerosis 0.7143678334200829 1.892906279607492 0.0583703340172312 1.0 1.0 15 Q99720,Q15165,P35637 3 +Enchondroma 0.7374946866842813 1.8883607615476217 0.058977535272793 1.0 1.0 7 P48735 1 +Furrowed tongue 0.8256950960317383 1.8776933910580216 0.0604231213485313 1.0 1.0 4 Q9H2M9,P61978 2 +Exostoses 0.794456934247063 1.8683194991356311 0.061717550293149 1.0 1.0 5 P48735 1 +Hemoptysis 0.823251190129183 1.8678468131194397 0.0617834261942653 1.0 1.0 4 Q9NZ08 1 +Abnormal muscle fiber morphology 0.4595884980230735 1.858952781486738 0.0630338316236938 1.0 1.0 67 Q99720,Q86U42,Q8N9N2,Q9Y5L0,P00846,O14979,P51114,O43676,Q70HW3,O95831,P23786,P00403,P35637,Q9BUK6,Q7Z406,P50402,P03886,P61978 18 +Congenital malformation of the right heart 0.730777638904994 1.8577790076172505 0.0632004033916944 1.0 1.0 7 P01889,Q12768,P40855,O15460,P21281 5 +Food allergy 0.8193005050374349 1.8519119318462924 0.0640384702772056 1.0 1.0 4 Q9Y5S9 1 +Stuttering 0.913896460918482 1.8486781999591395 0.0645042933640966 1.0 1.0 3 P03886 1 +Leg muscle stiffness 0.8157140373933464 1.837427635143203 0.0661467902787138 1.0 1.0 4 P00846 1 +Recurrent pancreatitis 0.9108741942322016 1.8372468169927416 0.0661734671365561 1.0 1.0 3 P03886 1 +Thick hair 0.7260590611742462 1.8362439418868497 0.0663215864634998 1.0 1.0 7 Q9BUK6,Q9UQE7 2 +Cerebellar cortical atrophy 0.9054743284597078 1.816798405109716 0.0692479871320692 1.0 1.0 3 O75312,Q9Y263 2 +Respiratory arrest 0.7816872565737061 1.8149901911103792 0.0695254168981116 1.0 1.0 5 O43772 1 +Abnormal serum iron concentration 0.8099523756057078 1.8141223488921416 0.0696588915268283 1.0 1.0 4 Q02241,Q15477 2 +Ventricular arrhythmia 0.5611192012201472 1.80880909581413 0.0704806667103927 1.0 1.0 33 P00846,O43772,Q03001,P00403,P03886 5 +Bloody diarrhea 0.8078231292517 1.8054986237426296 0.0709966906833043 1.0 1.0 4 Q02241,Q15477,Q6PGP7 3 +Spastic diplegia 0.642959952189945 1.8019113348257303 0.0715593565975698 1.0 1.0 24 Q99720,O00330,Q9H2M9,Q13509,P07602,P35637 6 +Urinary incontinence 0.5121614194105196 1.7873130664595205 0.0738869033257967 1.0 1.0 37 Q99720,O75298,P07602,P35637,Q06787 5 +Abnormality of the thoracic cavity 0.706988096605889 1.7854725370457156 0.0741847020599777 1.0 1.0 11 O95999,Q01844,Q92990,P01889,O15460 5 +Abnormality of the pituitary gland 0.4341979972184089 1.7814336989015012 0.0748416271272016 1.0 1.0 55 Q8WWQ0,O75874,Q03164,P48735,Q9BUK6,Q06787,Q4J6C6 7 +Degeneration of the lateral corticospinal tracts 0.7140366697218536 1.7811850371040716 0.0748822272402338 1.0 1.0 7 O75298,P35637 2 +Oval face 0.7729231468662969 1.7782466519014295 0.0753633539388625 1.0 1.0 5 Q96T58,Q01082 2 +Decreased plasma carnitine 0.7052158913401475 1.7769571116353071 0.0755752965684637 1.0 1.0 11 O43772,Q16836,P11310,P23786 4 +Muscle abnormality related to mitochondrial dysfunction 0.5344591566158969 1.7768508206635587 0.0755927877203372 1.0 1.0 35 P00846,O43676,P00403,O96000,Q9BUK6,P03886 6 +Impairment of activities of daily living 0.4230348875329924 1.7754982529597405 0.0758156537632956 1.0 1.0 48 Q99720,O75298,P07602,P35637,Q06787 5 +Increased csf lactate 0.4243534719033977 1.758010186501009 0.0787457760997338 1.0 1.0 50 O00330,P00846,O95831,P00403,O96000,P03886 6 +Abnormal middle phalanx morphology of the hand 0.7070798659656264 1.7554793765293712 0.0791773452562831 1.0 1.0 8 Q15233,Q8IWS0,Q9ULC3,Q03164,P02545 5 +Hand clenching 0.7084047812922853 1.755300981392263 0.0792078387174095 1.0 1.0 7 Q8TD16,Q03001 2 +Tremor by anatomical site 0.6264627183274053 1.749658336947958 0.0801772868992092 1.0 1.0 25 Q99720,P04350,P35637 3 +Disturbance of facial expression 0.7067453970272596 1.743236147657532 0.0812923737064552 1.0 1.0 6 Q8WXI9 1 +Clitoral hypoplasia 0.705369031304232 1.736960679804653 0.0823941115277544 1.0 1.0 6 Q9Y619,Q9H2M9,Q15042 3 +Hypoplastic labia minora 0.705369031304232 1.736960679804653 0.0823941115277544 1.0 1.0 6 Q9Y619,Q9H2M9,Q15042 3 +Hypermetropia 0.4161471609669401 1.736584448005667 0.0824605465678773 1.0 1.0 46 Q96T58,P35250,Q5H8A4,Q8WWQ0,A2RRP1,Q8WXI9,Q9UQ13,Q15056,O75175,P61978 10 +Clonus 0.528519144999484 1.7320263087238037 0.0832688783371662 1.0 1.0 35 Q99720,Q12768,O75298,Q9Y619,P07602,Q6PJG6,P35637,Q9BQT8,Q8N0X7 9 +Abnormality of the parathyroid gland 0.6569576402359858 1.7287728245741436 0.0838497616765794 1.0 1.0 20 Q96DF8,O75874,P03886,P48735 4 +Joint stiffness 0.4242275447854425 1.7261366844158683 0.0843228255046557 1.0 1.0 52 Q96T58,P35250,P01889,Q9H2M9,Q9Y2U8,O75874,Q9UQE7,Q96AY3,Q9NP72,O15460,Q15042,O75431,P48735,P18074,Q15056,P54802,P50402 17 +Late onset 0.6946064800227478 1.7258539381614697 0.0843736932285632 1.0 1.0 11 O00330,P22413,P31751,P17096 4 +Episodic respiratory distress 0.8812450612740585 1.7246842383083294 0.0845843930568257 1.0 1.0 3 P00846 1 +Pollakisuria 0.7867898239888647 1.7199996463664708 0.0854325058640437 1.0 1.0 4 O60934 1 +Arterial thrombosis 0.6989733788994452 1.7077568708759605 0.0876814647933272 1.0 1.0 6 Q9NZ08,O15460 2 +Macroorchidism 0.7831857471940616 1.7052948265432477 0.0881394519802352 1.0 1.0 4 Q06787 1 +Impaired visuospatial constructive cognition 0.6973957355824414 1.7045403770717793 0.0882801794222793 1.0 1.0 7 P03886 1 +Sparse lateral eyebrow 0.6971222330517977 1.7032766229414589 0.0885163132531949 1.0 1.0 7 Q92643,P61978,Q08J23 3 +Hyperglycemia 0.6948162265966253 1.6926163454042875 0.0905285177501693 1.0 1.0 7 O00330 1 +Abdominal aortic aneurysm 0.7788118893311538 1.687428895833866 0.091520911488907 1.0 1.0 4 P01889,O15460 2 +Abnormal b cell subset distribution 0.8714604012947875 1.6873282560598326 0.0915402506665197 1.0 1.0 3 O14920 1 +Ragged red muscle fibers 0.6694599878000489 1.6866487876312242 0.091670904889759 1.0 1.0 16 P03886,O95831,Q70HW3,P00846 4 +Hypoparathyroidism 0.6785636214740177 1.6756555657816437 0.0938056780867895 1.0 1.0 13 Q96DF8,P00403,P03886 3 +Abnormal circulating pyruvate family amino acid concentration 0.6472549117566375 1.675455610121272 0.0938448735509549 1.0 1.0 20 P03886,O96000,P00846 3 +Metaphyseal dysplasia 0.6895552157567644 1.673702981181968 0.0941889876068513 1.0 1.0 8 Q9HC07 1 +Retinopathy 0.6206172387809116 1.6705348485303677 0.0948135905707736 1.0 1.0 24 O00330,Q5H8A4,Q9NZ08,P00846,P01889,P18074,Q5JRA6 7 +Goiter 0.6908174920760494 1.6704147899367934 0.0948373254459036 1.0 1.0 6 O75874,Q9UPY3,P48735 3 +Abnormal full field electroretinogram 0.690055422662349 1.6669199935938883 0.0955303147087041 1.0 1.0 6 P00846 1 +Abnormal light and dark adapted electroretinogram 0.690055422662349 1.6669199935938883 0.0955303147087041 1.0 1.0 6 P00846 1 +Long eyelashes 0.5705336968883625 1.6655467865963878 0.0958037174877832 1.0 1.0 30 Q96T58,Q13724,Q9UID3,Q03164,Q9UQE7,Q9Y619,Q9UQ13,P21281,O60885,P20674,Q8WVM7,Q4J6C6 12 +Gangrene 0.6819460413963258 1.6646010186380271 0.0959923820083996 1.0 1.0 11 P01889,Q9NZ08,O15460,Q6UN15 4 +Increased muscle lipid content 0.6853166646950599 1.6609370880031626 0.0967260825517168 1.0 1.0 9 Q9BUK6 1 +Hyperextensibility of the finger joints 0.7694990201888484 1.6493166930811982 0.0990827715318112 1.0 1.0 4 Q9Y263 1 +Abnormality of hand joint mobility 0.7694990201888484 1.6493166930811982 0.0990827715318112 1.0 1.0 4 Q9Y263 1 +Tetraplegia tetraparesis 0.4074319755673283 1.6475037212745205 0.0994545519613967 1.0 1.0 46 O00330,O95831,P00846,P35637 4 +Large for gestational age 0.6801626656398199 1.6452351487020904 0.0999213277096535 1.0 1.0 10 O00330,P31751 2 +Elevated urinary carboxylic acid 0.6843631706063468 1.6407860612274818 0.1008418326956375 1.0 1.0 6 O96000 1 +Multiple enchondromatosis 0.7402523484176557 1.6403197035975812 0.1009387109004067 1.0 1.0 5 P48735 1 +Widely spaced incisors 0.8571914314858972 1.6327057896179469 0.1025308891966485 1.0 1.0 3 Q8WVM7,Q8WXI9 2 +Elevated urinary monocarboxylic acid level 0.8550282629099226 1.6244108934674526 0.1042881437041116 1.0 1.0 3 O96000 1 +Morphological abnormality of the pyramidal tract 0.6259100067810234 1.6231908199453533 0.1045486196549463 1.0 1.0 22 P11177,P00846,O75298,Q12768,O95831,Q9Y619,P35637,Q15056 8 +Retinal vascular tortuosity 0.6632512624151775 1.6154441809898914 0.1062145390928648 1.0 1.0 14 Q96DF8,P03886,P00846 3 +Abnormal circulating fatty acid anion concentration 0.6663758283718473 1.6149670045334894 0.1063178404445639 1.0 1.0 13 O43772,Q16836,P11310,P23786 4 +Abnormal sputum 0.7335880668283277 1.6120140114544994 0.1069588907658869 1.0 1.0 5 Q9NZ08 1 +Abnormal glial cell morphology 0.4179480258688811 1.601980292373555 0.109159967557082 1.0 1.0 56 P00846,O75874,O95831,Q6PJG6,P48735,P35637 6 +Abnormal circulating proteinogenic amino acid derivative concentration 0.6281161420282463 1.6012302228285653 0.1093259372024393 1.0 1.0 21 P03886,O96000,P00846 3 +Central scotoma 0.6718748830875823 1.597098837328426 0.1102436773250001 1.0 1.0 9 P00846 1 +Mitochondrial myopathy 0.5774497212502756 1.5954723201595338 0.1106066549869855 1.0 1.0 28 P00846,O43676,P00403,O96000,Q9BUK6,P03886 6 +Cardiac conduction abnormality 0.5677598768103422 1.5876860116699454 0.1123573577198238 1.0 1.0 29 O43772,P03886,P00403,P00846 4 +Misalignment of incisors 0.7538997409920334 1.585273054554672 0.1129043084108392 1.0 1.0 4 Q8WVM7,Q8WXI9 2 +Sensorimotor neuropathy 0.5837373924706206 1.583724117021257 0.113256514127334 1.0 1.0 27 P00403,P03886,O95831,P00846 4 +Abnormal circulating fatty acid concentration 0.6451358419676332 1.5822147292260575 0.1136005590049256 1.0 1.0 17 Q16836,O43772,P23786,P11310,Q4G0N4 5 +Dyspareunia 0.8439232120489261 1.5817734123957568 0.113701306676845 1.0 1.0 3 Q8WWQ0 1 +Keratoconjunctivitis 0.6699210121966159 1.5814746823410746 0.1137695433177861 1.0 1.0 8 P01889,Q9NZ08 2 +High myopia 0.6698539848415144 1.5766670487389884 0.1148721561606267 1.0 1.0 7 O15460 1 +Vasculitis 0.6677400624577836 1.57119342570319 0.1161377266995769 1.0 1.0 8 Q9NZ08,O15460 2 +Meningitis 0.6689989311899285 1.5699964358470455 0.1164159404619888 1.0 1.0 6 Q9NZ08,O15460 2 +Abnormal csf metabolite level 0.411715029166191 1.5685345055926656 0.1167564437058676 1.0 1.0 54 O00330,P00846,O95831,P00403,O96000,P03886 6 +Hepatic failure 0.3996651196962373 1.5677131166184 0.1169480991739881 1.0 1.0 46 Q16836,P00846,A2RRP1,P01889,O43772,P23786,Q9Y619,O15460,P03886 9 +Myositis 0.6668684244706201 1.5670824831736434 0.1170954130500918 1.0 1.0 8 Q9NZ08,P28070 2 +Demyelinating peripheral neuropathy 0.6582626553280077 1.5608214675175698 0.1185658807829757 1.0 1.0 12 P00846 1 +Abnormal csf protein level 0.663112705265956 1.5553346464134887 0.119866389978017 1.0 1.0 9 P00403,P03886 2 +Lower limb spasticity 0.4351103962733723 1.5437693584194312 0.1226442169280295 1.0 1.0 72 Q99720,O00330,P00846,Q8WXI9,Q9H2M9,Q12768,O75298,O95831,Q9Y619,P07602,P35637 11 +Narrow nose 0.7151087611236886 1.533258310729657 0.1252122220892946 1.0 1.0 5 O75431,Q9Y4L1 2 +Ascending tubular aorta aneurysm 0.7389216588709913 1.5235642081084435 0.127617609829854 1.0 1.0 4 Q06787 1 +Incomplete penetrance 0.5660141051518021 1.521784282714622 0.1280631409600328 1.0 1.0 28 P00846,O14979,Q9UJV9,Q92733,Q06787,P03886 6 +Morphological abnormality of the corticospinal tract 0.6370617016881813 1.5181115268496506 0.1289862857982007 1.0 1.0 16 P11177,P00846,O75298,Q12768,P35637,Q15056 6 +Toe walking 0.6131858413802228 1.5170365401754209 0.1292574587405308 1.0 1.0 21 Q99720,Q8TD16,O95831,P35637 4 +Abnormality of endocrine pancreas physiology 0.7110224838922614 1.515794515496456 0.1295713193087371 1.0 1.0 5 O00330,P16930 2 +Recurrent sinusitis 0.7367830779667494 1.5147380287271313 0.1298387598012755 1.0 1.0 4 Q13432,O14920 2 +Facial hypertrichosis 0.4046320141080375 1.511209768869524 0.130735014269145 1.0 1.0 53 Q96T58,Q8WWQ0,Q9UPP1,Q8WVM7,Q9BSJ2,Q01082,Q9Y2U8,Q9UQE7,Q03164,Q15042,P21281,O60701,P54802,P20674,Q08J23 15 +Neuroinflammation 0.8250730628096669 1.5092152288515042 0.1312437896881331 1.0 1.0 3 Q9NZ08 1 +Orchitis 0.8250730628096669 1.5092152288515042 0.1312437896881331 1.0 1.0 3 Q9NZ08 1 +Pleuritis 0.8250730628096669 1.5092152288515042 0.1312437896881331 1.0 1.0 3 Q9NZ08 1 +Pulmonary embolism 0.8250730628096669 1.5092152288515042 0.1312437896881331 1.0 1.0 3 Q9NZ08 1 +Round face 0.63891984187273 1.5087362731338785 0.1313661919558018 1.0 1.0 15 Q8WWQ0,Q32P28,Q03164 3 +Trichorrhexis nodosa 0.8248894933696069 1.5085076406381652 0.1314246526385183 1.0 1.0 3 Q15477,P18074 2 +Deep palmar crease 0.648680613596278 1.50240093977748 0.1329935938043456 1.0 1.0 11 Q69YQ0,Q9UQ13,O75431,P21281,P61978 5 +Pituitary adenoma 0.6495895528326775 1.4978043673161625 0.1341840858091942 1.0 1.0 10 P48735 1 +Non midline cleft lip 0.8200320867092759 1.4897781717959238 0.1362825723846232 1.0 1.0 3 O60934 1 +Limb dystonia 0.6351513534397795 1.4892874927125088 0.1364116798272876 1.0 1.0 15 Q99720,P35637 2 +Psoriasiform dermatitis 0.818429105746352 1.483594846413646 0.1379164374303219 1.0 1.0 3 P01889,Q15800 2 +Abnormal oral physiology 0.4017505702591369 1.4816698588504753 0.1384281608442128 1.0 1.0 53 Q96T58,Q15165,P01889,Q01082,Q13509,Q6UN15,Q02241,Q92804,O15460,P50995,P35637,Q8N0X7 12 +Narrow palpebral fissure 0.6298405102895192 1.4803167411451366 0.1387887375756287 1.0 1.0 16 Q96T58,Q96DF8,Q03164,Q8WXI9 4 +Abnormal astrocyte morphology 0.6206498173129074 1.4749934680620411 0.1402142995386033 1.0 1.0 18 O75874,P00846,P48735 3 +Sensory neuropathy 0.50490051722208 1.4745614554011637 0.1403304840184178 1.0 1.0 34 P03886,O95831,P00846,Q03001 4 +Contractures of the joints of the lower limbs 0.3980852858664676 1.474374860363488 0.140380689347066 1.0 1.0 51 Q99720,Q8TD16,O00330,P35637 4 +Eeg with multifocal slow activity 0.6472092886848608 1.4740885480168675 0.1404577515116567 1.0 1.0 8 Q8NC96 1 +Mixed hearing impairment 0.6464245454895379 1.467015980115373 0.1423717082969275 1.0 1.0 7 Q9NWM8,P78318 2 +Mania 0.6411985688981069 1.4657016241388292 0.1427295915179147 1.0 1.0 11 P03886 1 +Contractures of the joints of the upper limbs 0.4073940886448956 1.4646509378560777 0.1430161769732698 1.0 1.0 58 Q99720,Q96T58,Q15392,Q96AY3,Q13509,P23786,Q9Y619,Q15042,P35637 9 +Atrophy degeneration involving the corticospinal tracts 0.6334403107207536 1.4640273551955918 0.1431864742214983 1.0 1.0 14 P00846,Q12768,O75298,P35637,Q15056 5 +Axonal degeneration regeneration 0.7237092966477892 1.4607081634506744 0.1440955477862076 1.0 1.0 4 O95140,Q8TB36 2 +Bruxism 0.6451226609454142 1.459339494437366 0.1444716902514686 1.0 1.0 6 P61978 1 +Neoplasm of the adrenal cortex 0.6445943956350311 1.4584220068055929 0.1447242584395702 1.0 1.0 7 P48735 1 +Blepharophimosis 0.3989978174282128 1.455651955012505 0.1454888577515254 1.0 1.0 43 Q96DF8,P38159,Q13724,Q8WXI9,Q03164,Q9Y619,Q15056,O75175,O60701 9 +Ankylosis 0.6433025200999456 1.4508754770080228 0.146814537633156 1.0 1.0 6 P16435,P22413,P02545 3 +Bradycardia 0.6360316915742039 1.4505694419463744 0.1468997895414325 1.0 1.0 12 O43772,Q03001 2 +Fatigable weakness of swallowing muscles 0.6351388043850311 1.446128163951526 0.1481412575952827 1.0 1.0 12 Q92804,Q15165,P35637 3 +Lymphoproliferative disorder 0.8084874277136047 1.4452217306116464 0.1483956144319425 1.0 1.0 3 P17812 1 +Motor neuron atrophy 0.6001723979054008 1.4433492756867798 0.148922105381515 1.0 1.0 21 Q99720,Q15165,P35637 3 +Bilateral cryptorchidism 0.6383426325339894 1.4432484650071191 0.148950491411786 1.0 1.0 10 P48449,P36543,P78318 3 +Oral ulcer 0.6406983835074809 1.443184441904727 0.1489685210284301 1.0 1.0 8 Q9NZ08 1 +Muscle stiffness 0.6186605113976572 1.4417240403385725 0.1493802389039862 1.0 1.0 17 P07602,Q15392,P00846,P23786 4 +Abnormal circulating long chain fatty acid concentration 0.8052131232395499 1.4325754783764622 0.1519791936713734 1.0 1.0 3 P23786 1 +Abnormality of the hypothalamus pituitary axis 0.4039539759428852 1.4294981717039703 0.1528611000466839 1.0 1.0 58 Q8WWQ0,O75874,Q03164,P48735,Q9BUK6,Q4J6C6 6 +Basal ganglia calcification 0.6900600485036966 1.425969634350602 0.1538771073878906 1.0 1.0 5 P03886 1 +Limited hip movement 0.6248489817949682 1.4201665795187657 0.1555591907830957 1.0 1.0 14 Q8TD16,Q03001 2 +Increased serum iron 0.8006153785665486 1.41481218449061 0.1571235706639482 1.0 1.0 3 Q02241 1 +Decreased proportion of cd4 positive helper t cells 0.7116722421310054 1.410868234031103 0.1582834702529716 1.0 1.0 4 O14920 1 +Venous thrombosis 0.6250287498854337 1.407390550223538 0.15931161177184 1.0 1.0 13 Q9NZ08,P48735 2 +Abnormal circulating glutamine family amino acid concentration 0.6855157337527863 1.4064519389489676 0.1595899665288396 1.0 1.0 5 O96000 1 +Developmental cataract 0.3883216120852192 1.404281232778115 0.1602351205213708 1.0 1.0 49 Q15800,Q9H2M9,Q5SRE5,P48449,P00403,Q15042,P03886 7 +Postural tremor 0.6110596931858031 1.4012162839368076 0.1611494062569365 1.0 1.0 17 P04350,P03886,P00846,P35637 4 +Oral cavity bleeding 0.6325876995446684 1.4009797163529722 0.1612201387303655 1.0 1.0 6 Q02241,Q6UN15 2 +Impaired mastication 0.631759283790639 1.4006817128694753 0.161309273588377 1.0 1.0 8 O15460,Q13509 2 +Abnormal circulating carbohydrate concentration 0.4634285148978728 1.393994615924344 0.1633192305100632 1.0 1.0 37 O00330,Q70HW3,O95831,O96000,P03886 5 +Spinal muscular atrophy 0.6218731624601809 1.391461979324173 0.1640853813095435 1.0 1.0 13 Q99720,Q8TD16 2 +Joint laxity 0.4185208772915415 1.3905471099733548 0.1643628042291538 1.0 1.0 71 P35250,Q5H8A4,Q8WWQ0,Q8WVM7,Q8WXI9,Q9H2M9,Q96AY3,Q13509,Q15056,Q9Y619,Q9UQ13,Q9HC07,Q9BUK6,Q06787,Q32P28,Q96HY6,P61978,Q15334 18 +Urinary bladder sphincter dysfunction 0.6294626922241867 1.3897497377830237 0.1646048855995052 1.0 1.0 8 Q06787,O75298 2 +Esophageal carcinoma 0.7936076164569952 1.3877276254363746 0.1652200005752973 1.0 1.0 3 P25054,Q8N9N2 2 +Somatic mutation 0.3788299068797567 1.3832635589692233 0.1665840673420819 1.0 1.0 44 Q8N9N2,O95999,Q01844,P30154,O60934,O75874,Q9UNW1,Q92804,P61586,Q9UPY3,Q92733,P25054,Q13951 13 +Pharyngitis 0.7909273384725157 1.3773659833747995 0.1683991243486389 1.0 1.0 3 O15460 1 +Productive cough 0.6263863450791012 1.372052756846969 0.1700470149571753 1.0 1.0 6 P06748,P10644,Q86Y56,Q6UN15 4 +Ectrodactyly 0.6116331711267596 1.367521004196098 0.1714620582291217 1.0 1.0 15 Q99720 1 +Cutaneous syndactyly 0.624594190010687 1.3665602143171076 0.1717631949560396 1.0 1.0 8 Q9Y619,O60716,Q9Y2U8,P21281 4 +Iris hypopigmentation 0.6250805057862562 1.3659574432481238 0.1719523211600071 1.0 1.0 6 Q96T58 1 +Atrophic scars 0.6243913810541801 1.3627402542219564 0.1729643864993977 1.0 1.0 6 Q03001 1 +Insulin resistant diabetes mellitus 0.623779197632881 1.3626763850280403 0.1729845234972473 1.0 1.0 8 O00330,P31751 2 +Congenital hypothyroidism 0.6994206830907347 1.3600710359406094 0.1738074456863803 1.0 1.0 4 Q9Y263,P21281 2 +Impaired proprioception 0.458345580751052 1.352547883581722 0.1762001116225078 1.0 1.0 37 P00846,Q12768,O75298,Q9Y619,Q06787,P54802,Q8N0X7 7 +Generalized myoclonic seizure 0.4360884577464028 1.349152230415688 0.1772880747290819 1.0 1.0 39 O00330,P00846,P07602,Q01105,Q6PJG6,P49419,P03886 7 +Abnormal brain lactate level by mrs 0.6197583152962172 1.3472686433480656 0.1778937271930396 1.0 1.0 9 P03886 1 +Conical tooth 0.6716779110528182 1.346942886889598 0.1779986276343139 1.0 1.0 5 O60716,P21281 2 +Elevated hemoglobin a1c 0.7817069024141589 1.3417143895063195 0.1796886195624285 1.0 1.0 3 O00330,O75431 2 +Nasogastric tube feeding in infancy 0.6194417096434355 1.3399753364099565 0.1802533634438894 1.0 1.0 7 P07602 1 +Acne 0.6105562738937512 1.3342658506725658 0.1821167451020688 1.0 1.0 13 P22413,Q9NZ08,P01889,O14920,Q92542 5 +Hemiparesis 0.6077211627267518 1.3325038769121018 0.182694668346625 1.0 1.0 14 P00403,Q9NZ08,P03886 3 +Multiple lipomas 0.6178042786958733 1.3322465351193624 0.1827791895084534 1.0 1.0 7 Q9BUK6,P22413,Q9Y2U8 3 +Restrictive cardiomyopathy 0.7782308898914899 1.32827295303088 0.1840879514891664 1.0 1.0 3 O95235 1 +Delayed eruption of permanent teeth 0.7780575302715629 1.327602588265226 0.1843094290526621 1.0 1.0 3 Q5JRA6 1 +Nonketotic hypoglycemia 0.6669841439985571 1.3267366731591816 0.1845958051379714 1.0 1.0 5 P31751 1 +Prominent metopic ridge 0.6090580552719591 1.3266865613452 0.1846123882292418 1.0 1.0 13 O00330,O75845,Q5SRE5,P61978 4 +Abnormal retinal vascular morphology 0.379231046447839 1.3254993639246684 0.1850055802593673 1.0 1.0 48 Q96DF8,P22413,P00846,O43172,P04439,Q92620,P07602,Q96S66,Q15056,O43837,P03886 11 +Cone shaped epiphyses of the phalanges of the hand 0.6152311341486754 1.319943521952927 0.1868538752460422 1.0 1.0 6 P82673 1 +Fatigable weakness of respiratory muscles 0.6071874541460958 1.3172214389666603 0.187764409633854 1.0 1.0 13 Q92804,Q15165,P35637 3 +Increased serum pyruvate 0.501799470145168 1.3150461717804378 0.1884943855011596 1.0 1.0 32 O00330,Q70HW3,O95831,O96000,P03886 5 +Astrocytoma 0.611995488674355 1.3149506199920633 0.1885264986845771 1.0 1.0 10 P48735 1 +Focal dystonia 0.5774885918083217 1.314394882973864 0.1887133515756467 1.0 1.0 21 Q99720,P04350,P35637 3 +Axonal degeneration 0.6137235342316427 1.312894909560708 0.1892183624290893 1.0 1.0 6 Q9BQT8,Q6DKK2,Q8TB36 3 +Photophobia 0.4921712412697761 1.3099530293812027 0.1902117259353999 1.0 1.0 33 Q9NZ08,P04439,O43172,P01889,P48449,P07602,Q92620,Q96S66,O43837,P18074 10 +Abnormal blood glucose concentration 0.4344235742784788 1.3074418517705657 0.1910626913006106 1.0 1.0 89 O00330,P82673,Q8WWQ0,A2RRP1,O43772,O43676,P23786,P03886,O96000,P49419,P35610,P31751,Q4J6C6 13 +Aplasia hypoplasia of the skin 0.3844876175263094 1.3040320134202237 0.1922226674057419 1.0 1.0 53 Q96T58,Q15392,Q5H8A4,Q9Y2U8,Q03001,Q9Y619,O75431,P21281,P18074,Q06787,Q9NWM8,Q15334 12 +Increased connective tissue 0.6110096205702142 1.3001580343139103 0.1935468104991999 1.0 1.0 7 P31751,O75431,O95831 3 +Loss of subcutaneous adipose tissue in limbs 0.6838661024544916 1.295520634216035 0.1951406879204049 1.0 1.0 4 Q03252,O75431 2 +Clonic seizure 0.609297239757885 1.2921933222967317 0.1962902036681442 1.0 1.0 6 P07602,Q01082 2 +Short lingual frenulum 0.682540559642481 1.2900184674322854 0.1970442462003889 1.0 1.0 4 P21281,Q69YQ0 2 +Low plasma citrulline 0.9904826648538398 1.285049186402876 0.1987750965406882 1.0 1.0 2 P00846 1 +Multiple glomerular cysts 0.9904826648538398 1.285049186402876 0.1987750965406882 1.0 1.0 2 P00846 1 +Retinal arterial tortuosity 0.9904826648538398 1.285049186402876 0.1987750965406882 1.0 1.0 2 P00846 1 +Leber optic atrophy 0.9904826648538398 1.285049186402876 0.1987750965406882 1.0 1.0 2 P00846 1 +Abnormal protein o linked glycosylation 0.6808976970898941 1.2831991319860798 0.1994223200203482 1.0 1.0 4 Q10471,Q8N511 2 +Abnormal erythrocyte sedimentation rate 0.6073572027575553 1.2828993195559877 0.1995273512822235 1.0 1.0 7 P28070,O15460 2 +Papillary renal cell carcinoma 0.607257472400234 1.2826503106180205 0.199614615615618 1.0 1.0 6 Q92733 1 +Type i diabetes mellitus 0.6040359804714062 1.282590448055812 0.199635598402589 1.0 1.0 11 P00403,P03886 2 +Abnormal circulating amino acid concentration 0.3749910140577049 1.2815110004676236 0.2000142385767862 1.0 1.0 48 O00330,P03886,O96000,P00846 4 +Intestinal pseudo obstruction 0.6061617297840793 1.2786147854132757 0.2010327407561463 1.0 1.0 8 P00403,P03886 2 +Abnormal circulating free fatty acid concentration 0.6794892291347217 1.2773527872508263 0.2014777250546806 1.0 1.0 4 Q16836 1 +Rigidity 0.3775197051338029 1.277268635572961 0.2015074227124649 1.0 1.0 50 Q15392,P00846,P04350,Q8NC96,P07602,Q6PJG6,Q06787 7 +Type ii diabetes mellitus 0.4687960848213785 1.2750026531577927 0.2023083029115353 1.0 1.0 35 O00330,P22413,O43172,Q92620,P00403,P31751,Q15056,O43837,P03886 9 +Maturity onset diabetes of the young 0.9870836165873552 1.2728140636446346 0.2030840294632394 1.0 1.0 2 O00330 1 +Depressed nasal tip 0.7638424207810236 1.2726432857230563 0.2031446511997261 1.0 1.0 3 Q03164 1 +Brain neoplasm 0.6782312925170129 1.2721313558694802 0.2033264519880542 1.0 1.0 4 P25054,P21359,Q07864 3 +Lymphangioma 0.9853840924541118 1.2666994555886066 0.205262774758528 1.0 1.0 2 P48735 1 +Visceral angiomatosis 0.9853840924541118 1.2666994555886066 0.205262774758528 1.0 1.0 2 P48735 1 +Hemangiomatosis 0.9853840924541118 1.2666994555886066 0.205262774758528 1.0 1.0 2 P48735 1 +Small earlobe 0.6530268899367434 1.2666135160086358 0.2052935171893524 1.0 1.0 5 P10586 1 +Decreased cd4 cd8 ratio 0.761840789976781 1.2649072143598823 0.2059045909042289 1.0 1.0 3 P17812 1 +Deep plantar creases 0.6525431248514699 1.2645289933237915 0.206040221025773 1.0 1.0 5 P61978 1 +Rhizomelia 0.6019139904129827 1.2611604081425334 0.2072510598809822 1.0 1.0 9 Q03164 1 +Abnormality of the ovary 0.3799729411494255 1.257445789652967 0.2085922573050989 1.0 1.0 53 P35250,Q8WWQ0,Q01844,Q06787,O75312,O60934,O75874,Q5JTZ9,Q9UPY3,P48735,Q15056,Q03252,P31751 13 +Multifocal seizures 0.7597409462971783 1.2567926929358613 0.2088287126785868 1.0 1.0 3 Q6PJG6 1 +Neoplasm of the pituitary gland 0.5952110968393098 1.2565801863200612 0.20890569311875 1.0 1.0 13 P48735 1 +Neuronal loss in central nervous system 0.598730597836496 1.2563758342470237 0.2089797389696217 1.0 1.0 11 Q6PJG6,P35637 2 +Widened subarachnoid space 0.5568968878847426 1.2560942209633492 0.2090818111508676 1.0 1.0 23 P49419,P00403,O95831,P03886 4 +Bilateral sensorineural hearing impairment 0.5671526442858409 1.255498705772981 0.2092977776230467 1.0 1.0 21 P38159,Q13509,P07602,P00403,P35637,P18074,Q7Z406,P03886 8 +Peripheral demyelination 0.586897926575808 1.254397685041999 0.2096974935673468 1.0 1.0 16 P03886,P00846 2 +Abnormal epiphysis morphology of the phalanges of the hand 0.6010822774485188 1.2532365008478927 0.2101196498774671 1.0 1.0 7 P82673,Q9ULC3,Q5JRA6 3 +Asymmetric growth 0.599882898934913 1.2513508407759175 0.2108065042006446 1.0 1.0 9 Q96T58,P31751 2 +Abnormality of circulating adrenocorticotropin level 0.6004084411164103 1.250595967162508 0.2110819227030604 1.0 1.0 6 P16435,O00170,Q969G3,P10644,Q13423 5 +Upper airway obstruction 0.6728781810669235 1.249913442775869 0.211331168239919 1.0 1.0 4 P02545,Q96HY6 2 +Lower limb asymmetry 0.6001939545368167 1.2495919157242 0.2114486577968342 1.0 1.0 6 Q96T58 1 +Attenuation of retinal blood vessels 0.6001020912353262 1.2486019041956118 0.2118107155408999 1.0 1.0 7 O43837,Q96S66 2 +Keratitis 0.5985589390523643 1.244955965117717 0.2131479371900144 1.0 1.0 9 P01889,Q9NZ08 2 +Chorea 0.4107495558421323 1.242934709906563 0.2138918938111818 1.0 1.0 76 Q99720,P00846,P04350,P07602,Q01105,P35637,P18074,O60524,O60701,P03886,Q08J23 11 +Immunologic hypersensitivity 0.5156297366692587 1.2423463110418804 0.2141088154106087 1.0 1.0 29 Q9Y5S9,Q9NZ08,P01889,Q01082,Q9UID3,Q9UJV9,P18074,Q5JRA6,Q08J23 9 +Female sexual dysfunction 0.598283679819523 1.2406491051225257 0.2147354032893118 1.0 1.0 6 Q8WWQ0,O75298 2 +Moderate albuminuria 0.6703287676028109 1.2393337640892053 0.2152219196639375 1.0 1.0 4 O00330 1 +Abnormal c peptide level 0.6696955366116519 1.2367061659815803 0.2161961887402257 1.0 1.0 4 O00330 1 +Abnormality of the vasculature of the eye 0.396211830899187 1.234598352803482 0.2169800223554556 1.0 1.0 66 Q96DF8,P22413,P28070,Q9NZ08,P00846,O43172,P04439,P01889,Q92620,P07602,P18074,Q96S66,Q15056,O43837,P03886,Q9NW15 16 +Bulbous nose 0.4116017556818703 1.2318036579816876 0.2180224365568006 1.0 1.0 40 Q96T58,Q96DF8,P38159,Q9BSJ2,Q01082,Q9UQE7,P23786,O75431,P21281,O75845,Q06787 11 +Poikiloderma 0.7530384990174765 1.2309015750918146 0.2183596784454056 1.0 1.0 3 P18074 1 +Hepatic encephalopathy 0.6682733542798484 1.230805162747937 0.2183957441672772 1.0 1.0 4 A2RRP1 1 +Abnormality of the metopic suture 0.5852597586411088 1.230433717564833 0.2185347335913965 1.0 1.0 15 O00330,O75845,Q5SRE5,P61978 4 +Fair hair 0.6679277165305736 1.229371101520565 0.2189327000854497 1.0 1.0 4 Q13724 1 +Progressive gait ataxia 0.5932375072361405 1.229225996510324 0.2189870845685129 1.0 1.0 11 P07602,P00846,Q9NW15 3 +Obsessive compulsive trait 0.6431052193729946 1.223860414687439 0.2210048888945066 1.0 1.0 5 Q8WXI9 1 +Generalized onset motor seizure 0.3722448252962397 1.222628826977061 0.2214699200549015 1.0 1.0 50 O00330,P00846,P07602,Q01105,Q6PJG6,P49419,P03886 7 +Diastema 0.6423200111056143 1.2204771070747744 0.2222840627669486 1.0 1.0 5 Q8WVM7,Q8WXI9 2 +Skin nodule 0.5608601242447077 1.2196243407520886 0.2226073148106686 1.0 1.0 21 Q9NZ08,Q92990,P01889,Q9Y2U8,O75874,P34913,P48735,P35637 8 +Juvenile aseptic necrosis 0.66530612244897 1.218495158464513 0.2230358634949012 1.0 1.0 4 Q9Y619,Q9H3U1,Q8IWS0 3 +Ocular albinism 0.6414301840488742 1.2166431156277384 0.223740030787537 1.0 1.0 5 Q96T58 1 +Status epilepticus 0.3869244971993643 1.2154434212040406 0.2241970156273947 1.0 1.0 42 Q15392,O95999,Q9UID3,Q8NC96,P07602,Q01105,P49419,Q03252,Q9GZZ9 9 +Distal peripheral sensory neuropathy 0.6410635826891643 1.2150635766920912 0.2243418441017577 1.0 1.0 5 P03886 1 +11 pairs of ribs 0.5922729269092126 1.2115774759318525 0.2256741609096328 1.0 1.0 7 Q96T58 1 +Generalized osteosclerosis 0.747620260829979 1.2099843772840138 0.2262848876980279 1.0 1.0 3 Q15392 1 +Delayed ability to walk 0.3893794978261096 1.2076599132102397 0.2271781033536015 1.0 1.0 63 Q99720,P48449,Q96D71,Q01105,Q6PJG6,Q15042,Q9UQ13,P35637,O75175,P61978 10 +Restlessness 0.4503214928074607 1.2061651670822688 0.227753811825516 1.0 1.0 36 Q15165,P48449,Q6PJG6,Q92804,P35637,P49419 6 +Impaired vibration sensation in the lower limbs 0.5827643016478897 1.2044574408355446 0.2284128220944996 1.0 1.0 14 O75298,P00846 2 +Dysdiadochokinesis 0.5847080057784674 1.2033660849270025 0.2288346861244474 1.0 1.0 13 Q9BUK6,P04350 2 +Renal tubular dysfunction 0.4182708528830539 1.1942056296120742 0.2323975414962422 1.0 1.0 39 O00330,Q8IUX1,Q96CU9,O43676,Q9NX14,Q9H267,Q9NWS8,Q9NPL8,Q4G0N4,O96000,P40855,P00403,O75489,P16930,P03886 15 +Mastoiditis 0.7435196529627066 1.194163516121716 0.2324140114605284 1.0 1.0 3 O60934 1 +Abnormality of the mastoid 0.7435196529627066 1.194163516121716 0.2324140114605284 1.0 1.0 3 O60934 1 +Abnormal cd4 cd8 ratio 0.6359488344756199 1.1930288873282924 0.232858059851833 1.0 1.0 5 P17812 1 +Neurofibromas 0.6358274544516439 1.1925060489386468 0.2330628803435865 1.0 1.0 5 P21912,Q01082,P21359 3 +Eunuchoid habitus 0.9643099932019036 1.1910705004905209 0.2336259094280333 1.0 1.0 2 Q8WWQ0 1 +Horizontal eyebrow 0.634816680182862 1.1881523521448942 0.2347733919240027 1.0 1.0 5 Q96T58,Q8N201 2 +Concentric hypertrophic cardiomyopathy 0.741873916031996 1.187816615863825 0.2349056666551401 1.0 1.0 3 P03886 1 +Acquired abnormal hair pattern 0.6347290206162206 1.187774791230212 0.2349221485882431 1.0 1.0 5 P25054,P02545 2 +Widow s peak 0.6569355963756781 1.1837862314083796 0.2364976938729128 1.0 1.0 4 P21281,Q69YQ0 2 +Retinal arteriolar tortuosity 0.5850011109974842 1.183110079614429 0.236765523614139 1.0 1.0 10 P00846 1 +Progressive leukoencephalopathy 0.7400298416337567 1.1807067586884874 0.2377192356400692 1.0 1.0 3 Q9Y263 1 +Large earlobe 0.5846571500946126 1.1755606605388254 0.2397704835475411 1.0 1.0 7 Q96T58,Q15392 2 +Abnormal labia minora morphology 0.5843873474631591 1.1745722281099482 0.2401658995460944 1.0 1.0 8 Q9Y619,Q9H2M9,Q15042 3 +Retinal coloboma 0.5836720108046627 1.1730410213818885 0.2407793558901492 1.0 1.0 9 Q92620,Q9H2M9,Q9NP72,Q15042 4 +Soft skin 0.5836320962741509 1.1728482277890742 0.2408566740806317 1.0 1.0 9 Q9NWM8,P21281 2 +Insulin resistance 0.5649270448162201 1.1728152226600863 0.2408699122528736 1.0 1.0 18 O00330,P22413,Q96MF7,Q8NC56,O95140,O75431,P17096,Q03252,P31751 9 +Abnormal palmar dermatoglyphics 0.3642839214236857 1.1703222725946032 0.2418713020708516 1.0 1.0 48 P98175,A2RRP1,Q01082,Q5SRE5,Q9UID3,Q9UQE7,Q69YQ0,P40855,Q9UQ13,O75431,P21281,O60885,Q8WVM7,Q9Y263,P61978 15 +Elevated creatine kinase after exercise 0.6288028733233509 1.1622563588963009 0.2451313478462022 1.0 1.0 5 O43772 1 +Butterfly vertebrae 0.7351262197418575 1.161811639163382 0.2453119851930671 1.0 1.0 3 O75845 1 +Coma 0.4718482630722618 1.1612063287156014 0.245558001680568 1.0 1.0 33 O00330,O43772,P23786,P11310,Q9Y619,P35610,P31751 7 +Scaphocephaly 0.6511084183076579 1.1596438836543652 0.2461938262488532 1.0 1.0 4 P40855 1 +Aplasia hypoplasia of the cerebral white matter 0.5809821081991496 1.1581837157422792 0.2467890722673991 1.0 1.0 7 P03886 1 +Abnormality of the antitragus 0.953772943575796 1.1534162289819754 0.2487395834025123 1.0 1.0 2 Q92643 1 +Prominent antitragus 0.953772943575796 1.1534162289819754 0.2487395834025123 1.0 1.0 2 Q92643 1 +Abnormal posterior segment imaging 0.6494551753076996 1.152798201378784 0.2489932228218645 1.0 1.0 4 P04439,Q96S66 2 +Addictive behavior 0.6255920903434459 1.1484367262324418 0.250788319655038 1.0 1.0 5 P06748,P10644,Q6UN15 3 +Metrorrhagia 0.6255920903434459 1.1484367262324418 0.250788319655038 1.0 1.0 5 P06748,P10644,Q6UN15 3 +Diffuse alveolar hemorrhage 0.6255920903434459 1.1484367262324418 0.250788319655038 1.0 1.0 5 P06748,P10644,Q6UN15 3 +Poor fine motor coordination 0.5783036840499933 1.1471067855989026 0.2513374897677258 1.0 1.0 6 O00330 1 +Alkalosis 0.6477204198326268 1.1456170178903045 0.251953652656272 1.0 1.0 4 Q9Y619 1 +Panhypogammaglobulinemia 0.6474008324639475 1.1442942917026062 0.2525016098245412 1.0 1.0 4 Q15477,P18074 2 +Aplasia hypoplasia of the phalanges of the toes 0.7300238014280966 1.1421692101737864 0.2533836915703786 1.0 1.0 3 Q9ULC3,P21281 2 +Albuminuria 0.6238198412965228 1.140811013795507 0.2539485763265041 1.0 1.0 5 O00330 1 +Overlapping fingers 0.5764866753966583 1.138603608562872 0.2548685226573477 1.0 1.0 6 Q8TD16 1 +Pigmentary retinopathy 0.3566745015021016 1.1368734006338612 0.2555912131928006 1.0 1.0 45 P00846,P00403,Q96S66,Q9BUK6,O43837,P03886 6 +Abnormal circulating follicle stimulating hormone concentration 0.5760307756575563 1.1364703147775974 0.255759782464847 1.0 1.0 6 P16435,Q9UMX1,Q96MF7,Q969G3 4 +Lambdoidal craniosynostosis 0.7283236994219802 1.1356291288678575 0.2561118126285251 1.0 1.0 3 Q9ULC3,P61978 2 +Adrenal hyperplasia 0.7283236994219761 1.1356291288678415 0.2561118126285318 1.0 1.0 3 P10644,P21281 2 +Neck muscle weakness 0.5613442762387854 1.135335509212775 0.2562347695226368 1.0 1.0 17 Q99720,P35637 2 +Small basal ganglia 0.5755924894041708 1.134025822243793 0.2567837165754962 1.0 1.0 9 P00846 1 +Dermal atrophy 0.5249423147428443 1.1320855801961671 0.2575984566145979 1.0 1.0 25 Q96T58,Q15392,Q9Y2U8,Q03001,P18074,Q9NWM8,Q15334 7 +Supranuclear gaze palsy 0.5602886153148895 1.1296890109771864 0.2586072892935258 1.0 1.0 17 Q99720,P35637 2 +Very long chain fatty acid accumulation 0.6438683899483595 1.1296792200150103 0.2586114163947599 1.0 1.0 4 P40855 1 +Abnormal subarachnoid space morphology 0.5176899529186767 1.1240878352334909 0.2609757654372395 1.0 1.0 26 P49419,P00403,O95831,P03886 4 +Muscle fiber atrophy 0.5437597970149285 1.1221560959799484 0.2617960762077722 1.0 1.0 21 Q99720,P23786,P35637 3 +Muscle spasm 0.3680708861273516 1.1197839548908997 0.2628058383182852 1.0 1.0 54 Q5H8A4,Q15165,P00846,Q12768,O75298,P23786,P11310,Q92804,P51530,P35637 10 +Platyspondyly 0.4823241158516912 1.1195135560737146 0.262921110940423 1.0 1.0 31 P82673,O75874,Q96AY3,O95831,P48735,Q5JRA6,Q32P28 7 +Agitation 0.4822774950514007 1.1191889357831937 0.263059544598113 1.0 1.0 31 Q15165,P48449,Q6PJG6,Q92804,P35637 5 +Coronary artery atherosclerosis 0.7233551298615986 1.1165304061744146 0.2641951623641991 1.0 1.0 3 P34913 1 +Endocarditis 0.6181359861789921 1.116367177494448 0.2642649971226163 1.0 1.0 5 Q9NZ08 1 +Generalized joint laxity 0.5697960148306178 1.1133921742908708 0.2655400345167624 1.0 1.0 11 Q9BUK6 1 +Abnormal myeloid cell morphology 0.7215313015043465 1.1095256594017504 0.2672034814044128 1.0 1.0 3 Q9UJV9 1 +Periorbital fullness 0.5588788818602454 1.1066142511154475 0.2684607431348296 1.0 1.0 16 Q96T58,O75179,Q8WXI9 3 +Visual acuity test abnormality 0.6381766827060119 1.106152621513526 0.2686604657215641 1.0 1.0 4 P25054,Q13509 2 +Ventricular tachycardia 0.5651234551205616 1.104189627076278 0.2695108883504638 1.0 1.0 13 O43772,P23786 2 +Abnormality of the antihelix 0.5687335842108662 1.1036853055036056 0.269729672098606 1.0 1.0 10 Q9H2M9,Q5SRE5,Q15042 3 +Hyperinsulinemic hypoglycemia 0.5689698478790713 1.1034435202401995 0.2698346060829761 1.0 1.0 6 O00330 1 +Abnormality of thyroid physiology 0.3859717441462231 1.1023488828066672 0.2703100253675199 1.0 1.0 68 Q96T58,Q15477,P22413,Q8WWQ0,Q07021,Q13724,P00403,P21281,Q9BUK6,Q9Y263,Q06787,Q15056,P03886,P61978 14 +Aplasia hypoplasia of the breasts 0.5691049942223895 1.1015929680301384 0.2706386668154616 1.0 1.0 8 Q8WWQ0 1 +Diffuse cerebellar atrophy 0.614233022361771 1.0995955031041036 0.2715084021614502 1.0 1.0 5 Q06787 1 +Tube feeding 0.3675269828341331 1.0994862481505934 0.2715560290626508 1.0 1.0 55 Q99720,Q13724,P07602,Q01105,P35637,O60701,P61978,Q08J23 8 +Anal stenosis 0.636244709894402 1.0981737709330823 0.2721286171589203 1.0 1.0 4 O60934,Q08J23 2 +Abnormality of the proximal phalanx of the thumb 0.718123087385248 1.096444903934865 0.272884122114009 1.0 1.0 3 Q9ULC3,Q15233 2 +Synostosis of metacarpals metatarsals 0.7181230873852422 1.0964449039348436 0.2728841221140183 1.0 1.0 3 P16435,Q15233 2 +Eeg with burst suppression 0.5676715418605085 1.0958074838374718 0.2731630327044407 1.0 1.0 9 P49419 1 +Paraplegia 0.3584667788606155 1.094872184794349 0.2735726364789066 1.0 1.0 49 O00330,Q8WWQ0,P00846,Q9H2M9,Q12768,O75298,O95831,Q9Y619 8 +Xerostomia 0.561359751471697 1.0946529751691418 0.2736686975896527 1.0 1.0 14 Q92804,Q15165,P35637 3 +Abnormal renal vascular morphology 0.716763005780347 1.0912283699593566 0.2751724074326724 1.0 1.0 3 P42224,P21359 2 +Enlarged ovaries 0.7167630057803449 1.091228369959348 0.2751724074326762 1.0 1.0 3 P16435,P10644 2 +Scotoma 0.5640524336775642 1.0909968866877229 0.275274252516636 1.0 1.0 12 P03886,P00846 2 +Abnormality of coagulation 0.3651814178283106 1.090008185210611 0.2757095384823302 1.0 1.0 54 Q9Y5S9,A2RRP1,O75874,Q6UN15,Q9Y619,Q9UQ13,P48735,Q96AA3 8 +Polyneuropathy 0.5422740697652645 1.089875369799426 0.2757680475875381 1.0 1.0 20 P03886,O95831,P00846 3 +Progressive pes cavus 0.611930732074032 1.0897080536793171 0.2758417673284232 1.0 1.0 5 O75298 1 +Dicarboxylic aciduria 0.517736502270306 1.0879828474691566 0.2766026797951206 1.0 1.0 25 O43772,P23786,P48735,P11310 4 +Tachycardia 0.5332340823169655 1.0879022198585346 0.2766382760461279 1.0 1.0 22 O43772,P23786,Q03001 3 +Rib fusion 0.5653129932643309 1.0844361065940018 0.2781714819133127 1.0 1.0 9 Q96T58 1 +T lymphocytopenia 0.5652765248052569 1.0839877961220836 0.2783702098786489 1.0 1.0 7 O14920 1 +Aplasia hypoplasia involving the femoral head and neck 0.5645384745778431 1.0827324650702883 0.2789271895126615 1.0 1.0 6 Q96HY6,O95831 2 +Weight loss 0.3824541286752635 1.0805622693576715 0.27989187371838 1.0 1.0 67 Q99720,O00330,Q9NZ08,Q01844,P01889,O60934,Q6UN15,P11310,P07602,O15460,P35637,P18074,P35610 13 +Abnormality of the extraocular muscles 0.7129918810716365 1.0767753567502636 0.2815806372323217 1.0 1.0 3 Q13509 1 +Spastic paraplegia 0.3536738876432961 1.0752438385985266 0.2822655730342767 1.0 1.0 47 O00330,P00846,Q9H2M9,Q12768,O75298,O95831,Q9Y619 7 +Abnormal hair laboratory examination 0.5628861797519278 1.075014045269036 0.28236844013433 1.0 1.0 6 Q15477,Q6PGP7,P18074 3 +Hyperthyroidism 0.5627857157771041 1.0722360963321638 0.2836140012989827 1.0 1.0 7 Q9BUK6 1 +Abnormal lower motor neuron morphology 0.561879287800027 1.0702687356183418 0.284498362861237 1.0 1.0 10 Q99720 1 +Recurrent hand flapping 0.7110581208811151 1.069370680845887 0.2849026731434327 1.0 1.0 3 Q06787 1 +Recurrent paroxysmal headache 0.5614168356129914 1.068015693043184 0.2855134329862099 1.0 1.0 10 P03886 1 +T cell lymphoma 0.6288766068281278 1.0677811455431792 0.2856192449144905 1.0 1.0 4 O60934 1 +Delayed social development 0.709079730292278 1.0617999338868744 0.2883265198377027 1.0 1.0 3 Q13509 1 +Thin ribs 0.5581066292893053 1.061322901105533 0.2885431816219044 1.0 1.0 12 Q9Y619,Q32P28,O95831 3 +Fatigue 0.3873468356857689 1.0611437538113635 0.2886245762193038 1.0 1.0 72 Q9NZ08,Q15165,O95999,Q07021,P01889,Q01082,Q70HW3,Q6UN15,Q02241,P07602,Q92804,O15460,P11310,P50995,P35637,P18074,Q4J6C6 17 +Aphthous ulcer 0.5600985215622586 1.059564269239659 0.2893428761393433 1.0 1.0 7 Q9NZ08 1 +Dyspnea 0.4171757530194115 1.0592320581928485 0.2894941084088134 1.0 1.0 95 P00846,P01889,Q6UN15,P07602,Q92804,P03886,Q15165,O95831,P21281,O60524,Q8TCJ2,Q13724,O95235,P11310,P50995,P35637,P04350,P23786,Q9Y619,P51530,P49419 21 +Saccadic smooth pursuit 0.6048146738958977 1.0591791816323253 0.2895181842891903 1.0 1.0 5 Q06787 1 +Impaired vibratory sensation 0.4809310124552055 1.0584606610473994 0.2898454764375247 1.0 1.0 30 Q5TAQ9,P00846,Q12768,O75298,Q9Y619,O15020,Q06787,Q8N0X7 8 +Malar prominence 0.706902414144865 1.053473812989983 0.2921238900621445 1.0 1.0 3 O60934,Q96MF7 2 +Parkinsonism 0.4867295549963548 1.0501336615937211 0.2936566642374778 1.0 1.0 29 Q99720,P07602,P35637,P61457 4 +Vitritis 0.7059750428063809 1.0499294402752424 0.2937505547946752 1.0 1.0 3 P04439 1 +Esophageal neoplasm 0.5578103472439393 1.0487798628755225 0.2942794475793528 1.0 1.0 7 O60216,P42224,Q8N9N2,P25054 4 +Gingival fibromatosis 0.7049555980700813 1.0460345252722854 0.2955450925096261 1.0 1.0 3 Q15392 1 +Spondyloepimetaphyseal dysplasia 0.6012841937441055 1.0440532472891515 0.2964607548400477 1.0 1.0 5 O95831 1 +Abnormal renal tubule morphology 0.5239198328448464 1.034039476078934 0.3011177087908627 1.0 1.0 22 Q15056,P03886,P00846,P23786 4 +Repetitive compulsive behavior 0.7011021092031333 1.0313250894751398 0.3023883965778169 1.0 1.0 3 Q01082 1 +Dilated cardiomyopathy 0.4091364979357992 1.0287217524502883 0.3036104451815486 1.0 1.0 38 Q96T58,P09493,P00846,P23786,P00403,P03886 6 +Intellectual disability progressive 0.5528168071354969 1.026160577331962 0.3048159002823696 1.0 1.0 10 Q9H2M9,O95831 2 +Visual field defect 0.3884888072847055 1.0240487222450612 0.3058122625496362 1.0 1.0 40 P00846,P04439,P00403,O15460,O43837,P03886 6 +Macrovesicular hepatic steatosis 0.596161010422938 1.0221311803680777 0.3067188173695727 1.0 1.0 5 P23786 1 +Photoreceptor layer loss on macular oct 0.9157036029911592 1.0186144238357069 0.3083860538708329 1.0 1.0 2 Q96S66 1 +Abnormal optical coherence tomography 0.9157036029911592 1.0186144238357069 0.3083860538708329 1.0 1.0 2 Q96S66 1 +Abnormality of hepatobiliary system physiology 0.387146890372897 1.0185169102441114 0.3084323687098838 1.0 1.0 75 Q8TCJ2,Q16836,P00846,A2RRP1,Q8N511,P01889,O43772,P55263,Q9UID3,P23786,P11310,Q9Y619,O15460,P03886 14 +Optic neuropathy 0.5206844456327994 1.0153610101886708 0.3099337716606545 1.0 1.0 22 P03886,O96000,P00846 3 +Abnormal dentin morphology 0.6159946799178255 1.0148126824063224 0.3101951270813494 1.0 1.0 4 Q96AY3 1 +Abnormal metabolic brain imaging by mrs 0.5437345185149841 1.0147283033085843 0.3102353585215534 1.0 1.0 15 P07602,P00403,P03886 3 +Congenital contracture 0.3434254633095163 1.0141033848497598 0.3105334230706669 1.0 1.0 44 O00330,Q8N9N2,Q15392,Q96AY3,P11310,Q8TD16,Q96AA3 7 +Horizontal nystagmus 0.5201204308353443 1.012106800887869 0.3114869910025799 1.0 1.0 22 P00846,O95831,P07602,O15020,Q9NW15 5 +Confusion 0.5448973519879337 1.010454377327713 0.31227764681908 1.0 1.0 14 P01889,Q9Y619,Q9NZ08,Q16836 4 +Abnormal brainstem mri signal intensity 0.5240968014512158 1.010374590763139 0.3123158567349289 1.0 1.0 21 O95831,O96000,P03886 3 +Recurrent herpes 0.6951089501526846 1.0084926274899622 0.313218025271011 1.0 1.0 3 Q13432 1 +Abnormality of iron homeostasis 0.5929478693349406 1.0084005945282883 0.3132621876448387 1.0 1.0 5 Q02241,Q15477 2 +Increased susceptibility to fractures 0.3486583903683243 1.0082356733622349 0.3133413359597261 1.0 1.0 48 Q8N9N2,Q8WWQ0,Q13724,Q9Y2U8,O75874,Q96AY3,P48735,Q32P28 8 +Myoclonic seizure 0.3529164587159676 1.0077439121070182 0.313577418214501 1.0 1.0 51 O00330,P00846,P07602,Q01105,Q6PJG6,P49419,P03886 7 +Edema of the dorsum of hands 0.9123045547246768 1.0066951740423054 0.3140812819781304 1.0 1.0 2 Q9Y263 1 +Edema of the dorsum of feet 0.9123045547246768 1.0066951740423054 0.3140812819781304 1.0 1.0 2 Q9Y263 1 +Progressive spastic quadriplegia 0.5491698955308753 1.0066680532656602 0.3140943191520851 1.0 1.0 8 P07602,Q4G0N4,Q9Y263 3 +Abnormal exteroceptive sensation 0.3437820450889765 1.002682017059764 0.3160143091861491 1.0 1.0 45 Q9NZ08,O95831,P07602,O15460,Q06787,P54802,P61978 7 +Gastrointestinal infarctions 0.91060503059143 1.0007439457856264 0.3169506155813875 1.0 1.0 2 O15460 1 +Recurrent pharyngitis 0.91060503059143 1.0007439457856264 0.3169506155813875 1.0 1.0 2 O15460 1 +Glossitis 0.91060503059143 1.0007439457856264 0.3169506155813875 1.0 1.0 2 O15460 1 +Aqueductal stenosis 0.6121481108085479 0.9990454820826916 0.3177726591075207 1.0 1.0 4 Q9NPF4,P21359 2 +Cutaneous finger syndactyly 0.9092454112848404 0.995987087476936 0.3192564191212805 1.0 1.0 2 Q9Y619 1 +Hypermetric saccades 0.6907830756162497 0.9920484642788976 0.3211738844841099 1.0 1.0 3 Q9NW15 1 +Retinal hemorrhage 0.5456071725705036 0.991374958822998 0.3215025230898651 1.0 1.0 7 P22413 1 +Pancreatic islet cell hyperplasia 0.6904072684382985 0.9906214120671416 0.3218704782240877 1.0 1.0 3 P16930 1 +Cachexia 0.5367539338797159 0.9903299151962186 0.3220128891750007 1.0 1.0 16 Q99720,Q01844,O60934,P11310,P07602,P35637 6 +Recurrent fractures 0.4836750021919707 0.9869152704224304 0.3236841775133245 1.0 1.0 28 Q8WWQ0,Q13724,O75874,Q96AY3,P48735,Q32P28 6 +Proximal symphalangism 0.6892189431246372 0.9861106363988658 0.3240788247475425 1.0 1.0 3 Q15233 1 +Symphalangism affecting the phalanges of the hand 0.6892189431246372 0.9861106363988658 0.3240788247475425 1.0 1.0 3 Q15233 1 +Carcinoma 0.5435203586114253 0.9847747321315292 0.3247347348224174 1.0 1.0 6 P25054,P51532,Q07864,P43246 4 +Ambiguous genitalia male 0.9051665533650464 0.9817390707140068 0.3262284118717922 1.0 1.0 2 Q15392 1 +Neurodegeneration 0.5054480686940561 0.9814605832438776 0.3263656630417821 1.0 1.0 24 Q15165,O60934,Q5JTZ9,Q92804,P50995,P35637 6 +Cone shaped epiphysis 0.5436352129445088 0.9802115568932972 0.3269817009826528 1.0 1.0 9 P82673,O95831 2 +Abnormal cartilage morphology 0.542669204857889 0.979853393205023 0.3271584917508547 1.0 1.0 11 P48735 1 +Irregular menstruation 0.5858228372441474 0.9780106298878792 0.3280690667131236 1.0 1.0 5 Q06787,P02545,P10644 3 +Subcutaneous nodule 0.5289415371549792 0.9778594207699745 0.3281438574438073 1.0 1.0 18 Q9NZ08,P01889,Q9Y2U8,O75874,P48735,P35637 6 +Abnormal arterial physiology 0.5047473971712051 0.9772778176776094 0.3284316317999072 1.0 1.0 24 P22413,Q9NZ08,P01889,O15460,Q15056,Q9NWM8 6 +Knee clonus 0.9038069340584538 0.9769974317172816 0.3285704238488498 1.0 1.0 2 O75298 1 +Acne inversa 0.5854084753018698 0.9762458987935934 0.3289426228745802 1.0 1.0 5 O14920,Q92542,Q9Y4L1 3 +Glioma 0.5379282661704324 0.974931177971902 0.3295943994092527 1.0 1.0 14 O75874,P48735 2 +Broad palm 0.5404786648314065 0.9706498770644606 0.3317226595591338 1.0 1.0 6 O95831,Q69YQ0 2 +Patellar aplasia 0.5836613629576974 0.9688084821326524 0.3326407537378395 1.0 1.0 5 Q9Y619 1 +Hypogonadotropic hypogonadism 0.5031562649744793 0.96778383285019 0.333152339679359 1.0 1.0 24 Q8WWQ0,Q9H2M9,P00403,Q15042,Q15056,P03886 6 +Abnormal b cell morphology 0.5404770565523629 0.9662898076825436 0.333899184739006 1.0 1.0 10 Q13432,O60934,O14920,P17812 4 +Abnormal sternal ossification 0.5824656150420544 0.9637214349238274 0.3351856048262938 1.0 1.0 5 Q9Y619 1 +Spinal canal stenosis 0.5393311103987906 0.9596029156600174 0.3372551010785891 1.0 1.0 9 Q96T58,P22413,Q8IWS0,P10644 4 +Myalgia 0.3709293925082029 0.9589425473672942 0.3375876890024671 1.0 1.0 41 Q9NZ08,P01889,P23786,P11310,O15460,P51530,Q9BUK6,Q06787 8 +Difficulty walking 0.3758383048529441 0.9586863630267132 0.3377167704179591 1.0 1.0 71 Q99720,P00846,Q12768,O75298,Q8NC96,P07602,Q8TD16,P51530,P35637,Q9BUK6 10 +Genu varum 0.5383182008272409 0.9585366649324092 0.3377922121948056 1.0 1.0 11 Q9Y619,P22413,Q9Y5S9,Q96HY6 4 +Generalized hypopigmentation 0.5387002970941659 0.95658549239672 0.3387765142294126 1.0 1.0 9 Q96EV8,Q9Y2U8,O75312,Q15477 4 +Neoplasm of fatty tissue 0.5379210519336809 0.95392255146507 0.3401228472609512 1.0 1.0 10 P22413,P21912,Q9Y2U8,O95140,P25054,Q9BUK6 6 +Cerebral edema 0.5372129379262888 0.9520229574667096 0.3410853390693935 1.0 1.0 7 P11310,P23786 2 +Hip contracture 0.5364939433466859 0.9496105223770166 0.3423101898632845 1.0 1.0 11 Q8TD16 1 +Decreased circulating acth level 0.6000000000000052 0.9494293556233296 0.3424022859532534 1.0 1.0 4 O00170,Q969G3,P10644 3 +Headache 0.362481942558456 0.9476089533068094 0.3433285664944201 1.0 1.0 62 Q9NZ08,P00846,P01889,Q12965,P23786,P00403,O15460,P03886 8 +Downturned corners of mouth 0.4261745663487731 0.9465913989229128 0.3438470284420019 1.0 1.0 35 O00330,Q5H8A4,O60885,O75312,Q9Y2U8,Q9UQE7,Q9NP72,P21281,O75845,O75175,P61978 11 +Babinski sign 0.3865072619523599 0.9459055676439644 0.3441967534651904 1.0 1.0 80 Q99720,P00846,O75298,Q12768,O95831,Q6PJG6,P07602,P35637,O60701,Q8N0X7,Q9Y263 11 +Impotence 0.5358821115840777 0.9457963111715336 0.3442524874289809 1.0 1.0 7 Q8WWQ0 1 +Erectile dysfunction 0.5358821115840777 0.9457963111715336 0.3442524874289809 1.0 1.0 7 Q8WWQ0 1 +Abnormal neuron morphology 0.4833191861426471 0.9456830438478356 0.3443102734906955 1.0 1.0 27 Q99720,Q15165,Q5THJ4,Q92804,P35637 5 +Abnormal peripheral nervous system physiology 0.3395708027488328 0.94403931684553 0.3451495572117624 1.0 1.0 46 Q99720,Q13724,O95831,Q9Y619,P07602 5 +Optic nerve hypoplasia 0.5245766856287691 0.9394513571237586 0.3474990555410551 1.0 1.0 17 Q8WWQ0,Q13509,P61978,Q8WXI9 4 +Aplasia hypoplasia of the patella 0.5343777607517727 0.9387621926271768 0.3478528541560566 1.0 1.0 7 Q9Y619,Q96AY3 2 +Elevated circulating follicle stimulating hormone level 0.5968125244821019 0.9364614075896976 0.3490356737353275 1.0 1.0 4 Q96MF7 1 +Malignant neoplasm of the central nervous system 0.5025383014306986 0.9361093030470532 0.3492169136485641 1.0 1.0 23 Q96T58,O60934,O75874,P48735 4 +Severe global developmental delay 0.3599655949045292 0.936080031947602 0.349231983146498 1.0 1.0 61 Q8N201,Q5H8A4,P22413,P00846,Q9H2M9,O75312,Q9H270,P55263,Q9UID3,Q13509,O95630,P40855,P18074,O75175,O60701,P03886,Q00577 17 +Abnormality of mouth shape 0.3612651149429923 0.9352652003569508 0.3496516446642541 1.0 1.0 62 O00330,Q96DF8,Q5H8A4,O60885,O75312,P04350,Q9Y2U8,Q9UQE7,Q03001,Q9NP72,P21281,P18074,O75845,O75175,P61978,Q00577 16 +Spinal cord lesion 0.533108216579681 0.932829754058006 0.3509078760755277 1.0 1.0 7 Q12768,O75298 2 +Abnormal mitochondria in muscle tissue 0.5103455307015852 0.9326096603714206 0.3510215437352117 1.0 1.0 21 P00403,O96000,P03886 3 +Psychomotor deterioration 0.5324511844174543 0.9267389544241444 0.3540620869354836 1.0 1.0 9 Q03164 1 +Fetal distress 0.4909160706689149 0.9245834815812802 0.3551826086467897 1.0 1.0 25 Q96T58,P49419,O96000,P03886 4 +Pleural effusion 0.5312292093861681 0.9238914557501324 0.355542832076988 1.0 1.0 11 P01889,Q9NZ08 2 +Impaired t cell function 0.5316131596194775 0.9227431015442442 0.356141098579908 1.0 1.0 9 Q96DF8 1 +Periventricular cysts 0.5305169306189872 0.9207320854049192 0.3571903202919306 1.0 1.0 7 O00330 1 +Ovarian neoplasm 0.511544654571993 0.9186483788526204 0.3582795185276999 1.0 1.0 20 O60934,O75874,Q9UPY3,P48735 4 +Thick corpus callosum 0.6709638029903167 0.9171641236364284 0.3590566434226194 1.0 1.0 3 O75175 1 +Abnormal nipple morphology 0.3412258626347898 0.916756190795346 0.3592704139712106 1.0 1.0 49 Q5H8A4,Q8WWQ0,Q9H2M9,Q12768,P10586,Q5SRE5,Q9UQE7,P23786,Q9NP72,P18074,Q96AA3,P61978 12 +Abnormal insulin level 0.5033681609594076 0.9157839543262898 0.3597802209972986 1.0 1.0 22 O00330,Q16836,Q92620,O75431,O43837,P31751 6 +Urinary urgency 0.5291933042775274 0.9121496374743264 0.3616899513621647 1.0 1.0 8 O75298 1 +Contractures of the large joints 0.8847722637661461 0.9110541072985682 0.3622668654471317 1.0 1.0 2 Q9Y263 1 +Abnormal circulating nitrogen compound concentration 0.341424873867828 0.9041803956018348 0.3658997537197033 1.0 1.0 50 Q16836,A2RRP1,P61457,O43772,P23786,P11310,Q9Y619,P35610 8 +Protrusio acetabuli 0.6668109517543613 0.901581626879878 0.3672791546542284 1.0 1.0 3 Q96AY3 1 +Supraventricular tachycardia 0.6667800068004064 0.9014656708722746 0.3673407783875102 1.0 1.0 3 P02545,Q9HD47 2 +Limb undergrowth 0.3541488048989288 0.899861210322418 0.3681941150784977 1.0 1.0 42 Q15392,O75874,Q03164,P48735 4 +Broad nasal tip 0.3365424614163616 0.8979732629163566 0.3691998039289776 1.0 1.0 47 Q9UPP1,Q8WXI9,Q9H2M9,Q8TAQ2,P10586,O95831,Q15042,P21281,P36543,P61978,Q00577 11 +Abnormal morphology of the choroidal vasculature 0.8800135961930666 0.8947075352486895 0.3709434495597974 1.0 1.0 2 P04439 1 +Choroidal neovascularization 0.8800135961930666 0.8947075352486895 0.3709434495597974 1.0 1.0 2 P04439 1 +Enthesitis 0.8800135961930664 0.8947075352486883 0.3709434495597981 1.0 1.0 2 P01889 1 +Abnormal sacroiliac joint morphology 0.8800135961930664 0.8947075352486883 0.3709434495597981 1.0 1.0 2 P01889 1 +Enlargement of the wrists 0.8800135961930516 0.8947075352486377 0.3709434495598251 1.0 1.0 2 O95831 1 +Abnormal length of corpus callosum 0.8796736913664018 0.8935422221438846 0.3715668718210003 1.0 1.0 2 P48449 1 +Loss of consciousness 0.6644308089457929 0.8926697977431902 0.3720340288594874 1.0 1.0 3 P11310 1 +Speech articulation difficulties 0.6643998639918389 0.892554026342327 0.3720960483190074 1.0 1.0 3 P08754,P21359 2 +Hemiplegia hemiparesis 0.4424185472067095 0.892417108424042 0.3721694043712396 1.0 1.0 32 Q96T58,Q9NZ08,P01889,P00403,P03886 5 +Scleroderma 0.5649270207696568 0.8894519052456841 0.3737602599633547 1.0 1.0 5 Q9Y2U8,P02545 2 +Tetraparesis 0.4186061354091256 0.888756964877081 0.3741337089212164 1.0 1.0 35 O00330,P00846,P35637 3 +Hamartoma 0.5059473358920028 0.8877036821910481 0.374700164700358 1.0 1.0 20 P48735 1 +Spinal cord compression 0.5836576633499901 0.8832022534775057 0.3771270042747205 1.0 1.0 4 P51530,Q9UNW1 2 +Abnormality of the metaphysis 0.3321595022426319 0.8823762182829528 0.3775733918620947 1.0 1.0 45 O75874,Q9HC07,P48735 3 +Short philtrum 0.3476552935774302 0.8815431247913377 0.378023923399764 1.0 1.0 56 Q10471,Q9H2M9,Q96JM3,Q01082,Q9UID3,Q15042,P11233,O75175,Q08J23,Q9NP72,O75179,P25054,Q5H8A4,Q8WXI9,Q13620,O75431,O96028,Q96T58,Q8WWQ0 19 +Overtubulated long bones 0.6607187396295535 0.8787998513521409 0.3795098069010034 1.0 1.0 3 P21281 1 +Monochromacy 0.8752549286199756 0.8784218811482579 0.3797148141799691 1.0 1.0 2 A2RRP1 1 +Amelogenesis imperfecta 0.8752549286199702 0.878421881148239 0.3797148141799793 1.0 1.0 2 Q9HC07 1 +Dolichocephaly 0.4831690501261582 0.8777533171326798 0.3800776033545241 1.0 1.0 25 Q8N201,Q5H8A4,Q01082,Q03164,P21281,O75175,P61978,Q4J6C6 8 +Abnormal larynx physiology 0.5200269967246469 0.8775347446782905 0.3801962555733151 1.0 1.0 13 Q92804,Q15165,P35637 3 +Arthralgia 0.424823467647797 0.8749044313491927 0.3816259077374644 1.0 1.0 34 P35250,P28070,Q9NZ08,Q15800,P22413,P01889,Q9Y2U8,O15460,P18074,Q15056,Q96HY6 11 +Hypoglycemic seizures 0.519593163634805 0.8699162383255387 0.38434618069738 1.0 1.0 7 P31751 1 +Periauricular skin pits 0.5201135718383281 0.8698223705575376 0.384397484219769 1.0 1.0 11 Q9ULC3,Q69YQ0,P08754,Q9Y2W2,O96028,P61978 6 +Peroneal muscle atrophy 0.6568494467196306 0.864381592841459 0.3873783012409806 1.0 1.0 3 Q12768 1 +Gastritis 0.5585827950965012 0.8627713314257152 0.3882632044597784 1.0 1.0 5 Q15477 1 +Hypoplastic pubic rami 0.5780265478557888 0.8605473154098952 0.3894874132835333 1.0 1.0 4 Q5H8A4 1 +Aplasia hypoplasia of the pubic bone 0.5780265478557888 0.8605473154098952 0.3894874132835333 1.0 1.0 4 Q5H8A4 1 +Rib segmentation abnormalities 0.5780265478557888 0.8605473154098952 0.3894874132835333 1.0 1.0 4 Q5H8A4 1 +Abnormality of abdominal situs 0.5780265478557888 0.8605473154098952 0.3894874132835333 1.0 1.0 4 Q5H8A4 1 +Distal muscle weakness 0.3549694092738593 0.8577903546766811 0.3910082367010674 1.0 1.0 63 Q99720,Q8TD16,O95831,P00846 4 +Cupped ear 0.516363639007792 0.8502450895452829 0.3951888380605943 1.0 1.0 10 Q15392,P78318 2 +Impaired social interactions 0.3315869931681643 0.8470730485583658 0.3969544064063564 1.0 1.0 47 Q96T58,Q10471,Q8IUX1,Q96CU9,O43676,Q01082,Q9P0J0,Q9NX14,Q13509,Q9NPL8,O96000,Q15067,P21359,O75489,Q06787,Q9GZZ9,P03886 17 +Nodular goiter 0.8647178789938788 0.8425912831052971 0.3994570678841378 1.0 1.0 2 Q9UPY3 1 +Ventricular hypertrophy 0.3867340274152138 0.8415384753440056 0.4000463399191307 1.0 1.0 38 Q07021,Q13724,O43772,P23786,P00403,O75431,P03886 7 +Pulmonary edema 0.6496786337337805 0.8377730441450462 0.4021581806650887 1.0 1.0 3 Q13724 1 +Abdominal obesity 0.6494389663379978 0.8368863513321266 0.4026564529712648 1.0 1.0 3 O75312,Q13620 2 +Underdeveloped supraorbital ridges 0.5135529684227228 0.8368276850022879 0.4026894332503006 1.0 1.0 10 P98175,Q6PGP7,Q9ULC3,Q08J23 4 +Vascular neoplasm 0.4035195346913617 0.8365181596628 0.4028634650114302 1.0 1.0 36 Q96T58,Q12768,Q9Y2U8,O75874,Q9UQ13,P48735,P21281 7 +Abnormal connection of the cardiac segments 0.3347173193257155 0.8355656197918586 0.4033993167848324 1.0 1.0 50 Q96T58,Q15477,P35250,Q9Y5S9,P98175,Q6PGP7,Q96DF8,P01889,Q8TAQ2,Q12768,Q9ULC3,Q69YQ0,O15460,P21281,Q15056 15 +Inverted nipples 0.5103581233655868 0.8318889383401971 0.4054716361651218 1.0 1.0 6 Q96AA3 1 +Barrett esophagus 0.6473988439306536 0.8293457103344377 0.4069088122508273 1.0 1.0 3 O60216,Q8N9N2 2 +Angiofibromas 0.6473916261840327 0.829319055262415 0.4069238910842307 1.0 1.0 3 P21912 1 +Adenoma sebaceum 0.6473916261840327 0.829319055262415 0.4069238910842307 1.0 1.0 3 P21912 1 +Infectious encephalitis 0.5118672089292331 0.8291453108221474 0.4070221868671122 1.0 1.0 9 P01889,Q9NZ08,O95999,Q9Y4L1 4 +Atrophy degeneration affecting the brainstem 0.511176877929608 0.8277412193716067 0.4078170700928674 1.0 1.0 8 P20700,Q13813,O00429,O60313 4 +Abnormal circulating proline concentration 0.8599592114207839 0.8265202008203569 0.4085090636806927 1.0 1.0 2 O96000 1 +Aplasia of the uterus 0.510885788780198 0.8263858151509988 0.4085852673911763 1.0 1.0 8 Q9Y5S9,Q9UNW1 2 +Generalized clonic seizure 0.549499982477017 0.8247785421324452 0.4094973311429175 1.0 1.0 5 P07602 1 +Lymphopenia 0.4789856827894559 0.8245686641463499 0.4096165179076303 1.0 1.0 24 Q13432,Q15477,P28070,Q6PGP7,O60934,O14920,P17812 7 +Gonadal neoplasm 0.4741047482723433 0.8232702740537453 0.41035431390844 1.0 1.0 25 O95999,Q01844,O60934,O75874,Q9UPY3,P48735 6 +Metatarsus adductus 0.5084851758601738 0.8203291926875963 0.4120284687317004 1.0 1.0 13 Q15392,Q9H2M9,Q13509,Q03252,Q08J23 5 +Short chin 0.5084892133825141 0.8186198062517434 0.413003363129703 1.0 1.0 7 Q03001 1 +Stomatitis 0.5079812660104445 0.817842610110848 0.4134470638297414 1.0 1.0 13 Q9NZ08,Q6UN15 2 +Proximal muscle weakness 0.3495469359157351 0.8170180920475217 0.4139180889839258 1.0 1.0 62 Q99720,P00846,P51114,P11310,Q8TD16,P51530,P35637,Q9BUK6,Q7Z406,Q9BQT8 10 +Organic aciduria 0.3746354120083844 0.8167163879506439 0.414090523806959 1.0 1.0 39 O43772,P23786,P11310,O96000,P48735 5 +Subependymal cysts 0.8569000679809472 0.8162270653348582 0.4143702797585791 1.0 1.0 2 O00330 1 +Thick upper lip vermilion 0.5081012960026196 0.8114362647109068 0.4171151803976849 1.0 1.0 9 O75845,Q9UID3,Q08J23,Q9UNW1 4 +Aplasia hypoplasia of the ribs 0.4886406259905063 0.8110508505212124 0.4173364693145269 1.0 1.0 21 Q96T58,Q12768,Q03164,Q9Y619,P21281 5 +Oculogyric crisis 0.5066491905801839 0.8039902526312735 0.4214026044045384 1.0 1.0 10 Q01105,O00429,P61457 3 +Tibial bowing 0.5635839957391705 0.8029033888367577 0.422030577176181 1.0 1.0 4 Q32P28 1 +Pectus excavatum 0.3655325238562923 0.8027247322354711 0.4221338546176758 1.0 1.0 75 Q8N201,O00330,P35250,P78318,O60885,Q9H2M9,Q9UQE7,Q03164,Q9Y2W2,Q69YQ0,Q15056,Q9UQ13,O75431,Q9BUK6,Q06787,P50402,P61978,Q08J23 18 +Large placenta 0.640126080851418 0.8025725423548237 0.4222218439149809 1.0 1.0 3 Q6PGP7 1 +Epistaxis 0.504743187532837 0.8018881403610699 0.4226176669916199 1.0 1.0 13 P01889,O15460,Q6UN15 3 +Ankle clonus 0.5017118142955397 0.7994379819168569 0.4240364941455707 1.0 1.0 15 O75298,P07602,Q9NP72,Q8N0X7,Q9NW15 5 +Abnormality of the menstrual cycle 0.3267800811056588 0.7979413670760693 0.424904516162462 1.0 1.0 47 Q9BUK6,Q8WWQ0,P31751,Q6UN15 4 +Adenomatous colonic polyposis 0.5622444497641674 0.7975939310711363 0.4251061740275366 1.0 1.0 4 P25054,Q07864 2 +Foot acroosteolysis 0.5612705563355795 0.7937380225795534 0.4273479600771672 1.0 1.0 4 O75431 1 +Osteolysis involving bones of the feet 0.5612705563355795 0.7937380225795534 0.4273479600771672 1.0 1.0 4 O75431 1 +Poor eye contact 0.3804619772921849 0.789700243978897 0.4297028488361991 1.0 1.0 38 Q96T58,Q10471,Q8IUX1,O43676,Q01082,Q9P0J0,Q9NPL8,O96000,Q06787,Q9GZZ9,P03886 11 +Overweight 0.5013941158717257 0.7860683775218265 0.4318274291574659 1.0 1.0 7 O00330 1 +Multiple prenatal fractures 0.5001080255451065 0.7801889668438964 0.4352796555836433 1.0 1.0 7 Q32P28 1 +Sparse body hair 0.5004583523875045 0.7747024591484006 0.4385154975598762 1.0 1.0 10 P48449,Q8WWQ0 2 +Fever 0.3691932752009084 0.774545116041109 0.4386084991376568 1.0 1.0 80 P22413,Q9NZ08,P28070,P00846,P01889,Q12965,Q03001,P23786,Q6UN15,P00403,P07602,O15460,Q9HC07,P18074,P35610,P03886,P61978 17 +Symptomatic seizures 0.4996845471214651 0.7744703102730075 0.4386527189328579 1.0 1.0 8 P31751 1 +Abnormal female reproductive system physiology 0.3383270448870928 0.7732638151802862 0.4393662659457888 1.0 1.0 57 Q8WWQ0,P01889,O60934,O75298,Q6UN15,Q9BUK6,Q06787,P31751 8 +Abnormal paranasal sinus morphology 0.4814264435278352 0.7710927465555549 0.4406519596489104 1.0 1.0 21 O14920,O60934,P28070 3 +Abnormality of skeletal maturation 0.3739578355659117 0.7708103224689266 0.4408193678765286 1.0 1.0 84 Q8WWQ0,Q15800,Q5H8A4,A2RRP1,P22413,O95831,Q03164,P48449,Q9Y619,Q9UQ13,P18074,Q9BUK6,Q06787,Q15056,O75179,Q08J23 16 +Loss of ability to walk 0.4971319766846168 0.7695934572766178 0.4415410873070868 1.0 1.0 14 P00846 1 +Abnormal renal pelvis morphology 0.3224479005348948 0.7682808733081347 0.4423203353478122 1.0 1.0 46 Q96T58,P98175,Q9H2M9,Q12768,O60934,Q9ULC3,P23786,Q9NP72,P40855,Q15042,P21281,P25054,Q5JRA6,Q8N0X7,P61978,Q08J23 16 +Neoplasm of the small intestine 0.5356171216391588 0.7672488363540245 0.4429335818299058 1.0 1.0 5 P25054,P21912,P02545 3 +Abnormal sacrum morphology 0.4173411460822198 0.7659640495668756 0.4436976935117958 1.0 1.0 33 P35250,Q5H8A4,P22413,P01889,Q03164,Q15056,P61978,Q08J23 8 +Supernumerary spleens 0.4962670030451122 0.7626706136373547 0.4456598602533397 1.0 1.0 7 O96028,Q9ULC3,Q86Y56 3 +Abnormality of salivation 0.3590667781655873 0.7626252066748743 0.4456869473691038 1.0 1.0 40 Q96T58,Q15165,P01889,Q01082,Q92804,P50995,P35637,Q8N0X7 8 +Celiac disease 0.6290377422645506 0.7621044705493233 0.4459976548847884 1.0 1.0 3 Q9Y5L0,Q13043 2 +Gliosis 0.3769663272536775 0.760960387512722 0.4466807277636759 1.0 1.0 38 P00846,P35637 2 +Trigonocephaly 0.4970135593183112 0.7605996858091034 0.4468962074891884 1.0 1.0 12 O00330 1 +Mild short stature 0.6284195427121558 0.7598616643865386 0.4473372786170644 1.0 1.0 3 P10644 1 +Red eye 0.4933743828881399 0.7574654219073399 0.4487710742788591 1.0 1.0 15 P01889,Q9NZ08,P28070 3 +Male sexual dysfunction 0.4967758615178673 0.7573593939228108 0.448834576503156 1.0 1.0 10 Q8WWQ0,O75298 2 +Increased adipose tissue 0.5509517320691153 0.7531143257373532 0.4513812165196267 1.0 1.0 4 P31751 1 +Heterotaxy 0.5313482852821518 0.7497087049395792 0.453430163609908 1.0 1.0 5 Q5H8A4 1 +Gait ataxia 0.3453038041673815 0.747579456730674 0.4547138597783071 1.0 1.0 64 Q5H8A4,P00846,Q5THJ4,P04350,Q9UID3,P07602,Q6PJG6,P18074,Q06787,P03886,Q9NW15 11 +Proximal tubulopathy 0.469345305979282 0.7443966718855082 0.4566365318358119 1.0 1.0 23 P00403,O96000,P03886 3 +Preaxial foot polydactyly 0.5484548209169389 0.7433515830905094 0.4572688491833716 1.0 1.0 4 Q9ULC3 1 +Abnormality of pulmonary circulation 0.4500721663949659 0.7380113818152749 0.4605075327026515 1.0 1.0 27 P22413,Q9NZ08,P01889,O95235,P00403,O96000,P03886 7 +Fatigable weakness of bulbar muscles 0.4893722740028234 0.7374385601860073 0.4608556933314305 1.0 1.0 15 Q92804,Q15165,P35637 3 +Abnormal dermatoglyphics 0.3401317149616397 0.7365862289684226 0.4613740119790441 1.0 1.0 61 P35250,A2RRP1,Q9H2M9,Q01082,Q9UID3,Q9UQ13,Q15042,P61978,P98175,P40855,P21281,Q5SRE5,Q9UQE7,O75431,O60885,Q69YQ0,Q15056,Q9Y263,Q8WVM7 19 +Abnormal pleura morphology 0.4779793238942295 0.7349793649509646 0.4623520613781964 1.0 1.0 20 P01889,Q9NZ08,O15460,Q9UPY3 4 +Skin appendage neoplasm 0.5462507919489209 0.7347570976045006 0.4624874397901086 1.0 1.0 4 P25054,Q9UPY3 2 +Nephropathy 0.4806239066214686 0.7341330279127465 0.4628676658279926 1.0 1.0 19 O00330,P03886 2 +Laryngeal cleft 0.8320870156356225 0.7339518573148223 0.4629780800127021 1.0 1.0 2 Q01082 1 +Abnormal corneal epithelium morphology 0.4897616196973943 0.7331902469253542 0.4634424030527357 1.0 1.0 14 P01889,Q9NZ08 2 +Cerebral dysmyelination 0.4875135748960626 0.7286074823643867 0.466241800219854 1.0 1.0 6 P07602 1 +Abnormality of the nasal tip 0.3746810678120957 0.7284583307672449 0.4663330674472608 1.0 1.0 88 Q8N201,Q8TAQ2,Q9H2M9,Q01082,Q03164,Q15042,O75845,P36543,P61978,Q9UPP1,Q9BSJ2,O95831,P21281,Q06787,Q96DF8,P38159,Q8WXI9,P10586,Q9UQE7,O75431,Q96T58,P23786,Q00577 23 +Neoplasm of the tracheobronchial system 0.8290278721957767 0.7239709281579767 0.469083583247198 1.0 1.0 2 Q9UPY3 1 +Hypocalcemia 0.4887109442788422 0.7235855215041914 0.4693202327618624 1.0 1.0 13 Q96DF8 1 +Alternating esotropia 0.6181641301727343 0.7228780951339872 0.4697547823507624 1.0 1.0 3 P25054 1 +Increased total bilirubin 0.5429578565498653 0.7219581394053916 0.4703202144465759 1.0 1.0 4 P23786 1 +Serositis 0.4722960426350429 0.7209296412119888 0.4709528047200919 1.0 1.0 21 Q9NZ08,P01889,Q8N1F7,Q8NFH4,Q12965,Q9Y5K6,O15460,P52565 8 +Abnormality of female external genitalia 0.4037813233733798 0.7205331167850028 0.4711968172142553 1.0 1.0 34 Q96T58,Q15392,O60885,Q9H2M9,Q9NX14,Q9UQE7,Q9UNW1,Q69YQ0,Q9Y619,Q9NP72,P40855,Q15042,P10644,O60216,P02545,Q08J23 16 +Striae distensae 0.4871165726719851 0.7168601325005166 0.4734604035836496 1.0 1.0 8 Q96T58,P22413,P10644,Q15334 4 +Sarcoma 0.3281960991993907 0.7133103549535089 0.4756537312580491 1.0 1.0 54 Q15392,P62899,Q01844,O60885,O60934,Q01082,O75874,Q13126,Q92804,Q9UPY3,P48735,P21281,P25054 13 +Focal t2 hyperintense brainstem lesion 0.4787137511298781 0.7112351444761769 0.4769385336261253 1.0 1.0 18 O96000,P03886 2 +Uncombable hair 0.8246091094493537 0.7096224840016351 0.4779382729875636 1.0 1.0 2 Q15477 1 +Neonatal respiratory distress 0.4668124500095331 0.7092693994318958 0.4781573141076709 1.0 1.0 22 O96000,P49419,P23786 3 +Rhabdomyolysis 0.4849625325766019 0.7054662319127437 0.4805201392802609 1.0 1.0 13 O43772 1 +Bone pain 0.4658152086707481 0.7037385145987105 0.4815956303841777 1.0 1.0 22 P22413,Q9Y2U8,O75874,Q6UN15,P07602,P48735 6 +Neoplasm of the nervous system 0.3233411457040135 0.7023398150445741 0.4824672688778806 1.0 1.0 43 Q96T58,P51532,P21912,Q01844,O60885,O60934,Q01082,O75874,P42771,P21359,Q9UPY3,P48735,P10644,P25054,P02545,Q07864 16 +Abnormality of cranial sutures 0.3591889442345301 0.7021516414569461 0.4825845998767164 1.0 1.0 78 Q9Y2U8,O75845,P36543,P61978,Q08J23,O00330,P98175,O95831,P40855,P21281,P18074,Q5SRE5,Q9ULC3,Q96AY3,Q9UQE7,O75431,Q32P28,Q96T58,P22413,Q69YQ0,Q9Y619,Q00577 22 +High anterior hairline 0.476773687212409 0.7011749884575732 0.483193816765076 1.0 1.0 18 Q96T58,Q92643,P21281,O75179 4 +Slender long bone 0.4838219534111866 0.6999686087436962 0.4839469087480417 1.0 1.0 13 Q9H2M9,Q32P28 2 +Bronchitis 0.5368814097010084 0.698477240341328 0.4848787864818842 1.0 1.0 4 O60934 1 +Bone marrow hypercellularity 0.4828507135114593 0.6974836278499295 0.485500181864321 1.0 1.0 8 P06748,P40763,P10644,Q6UN15 4 +Aplasia hypoplasia of the eyebrow 0.3774666295707821 0.6971154037601546 0.4857305749756266 1.0 1.0 37 Q5SRE5,Q92643,P48449,Q9UQ13,Q8WVM7,P61978,Q08J23 7 +Absent brainstem auditory responses 0.6104766853097761 0.6954487575714755 0.4867741136997565 1.0 1.0 3 Q13724 1 +Pilomatrixoma 0.610094915587523 0.6940935393097166 0.4876235499823704 1.0 1.0 3 Q9UPY3 1 +Bladder diverticulum 0.482582341523781 0.6930296791418498 0.4882909262525547 1.0 1.0 9 Q15056,Q9NWM8 2 +Limitation of joint mobility 0.3734882756804623 0.6927484507103189 0.4884674275593319 1.0 1.0 90 P35250,P01889,Q9H2M9,Q9Y2U8,O15460,Q15042,P48735,P54802,P50402,O14979,O75874,Q03001,Q9NP72,P18074,Q96AY3,Q9UQE7,Q8TD16,O75431,Q96T58,P22413,P23786,Q15056,Q8WVM7 23 +Disproportionate short limb short stature 0.478923505669651 0.6926537159273698 0.4885268916421812 1.0 1.0 16 Q15392,Q03164 2 +Schizophrenia 0.4783406876919006 0.6897326808263379 0.4903623100727372 1.0 1.0 16 Q9BUK6 1 +Fused cervical vertebrae 0.4792131363053507 0.6857247075952396 0.4928867231752769 1.0 1.0 7 P22413,Q9Y5S9 2 +Neoplasm of the adrenal gland 0.4798475273068888 0.6846866498985759 0.4935416751153958 1.0 1.0 14 P48735 1 +Arterial stenosis 0.4786063679307386 0.6840065794442746 0.4939710111435242 1.0 1.0 15 P42224,P35250,P21912,P78347,P22413,P01889,P21359,P34913,Q15056,P02545 10 +Kyphoscoliosis 0.3222759632665347 0.6818939399255656 0.4953060176184234 1.0 1.0 52 P04350,Q9ULC3,Q96AY3,Q13509,Q9NP72,Q9NWM8,Q15042,Q9HC07,Q5MNZ6,P18074,O60524,P51530,Q8N0X7,P36543 14 +Alveolar ridge overgrowth 0.8144119646498742 0.6768334534232272 0.4985116301256309 1.0 1.0 2 Q15392 1 +Abnormal facial expression 0.3901304274675271 0.6746358042738249 0.4999071794438698 1.0 1.0 35 Q8WXI9,P51530,Q9BUK6,Q9Y263,Q06787,Q9GZZ9,P49419 7 +Abnormality of the mitochondrion 0.3728420854233533 0.6745920004948655 0.4999350167419751 1.0 1.0 91 O00330,P11177,Q16836,P00846,O43772,O43676,Q70HW3,P23786,P11310,P00403,O96000,Q4G0N4,P51530,P35637,Q7Z406,P03886,Q4J6C6 17 +Prenatal movement abnormality 0.3280124203715517 0.670547176555821 0.5025090431594208 1.0 1.0 57 Q8N9N2,Q5H8A4,P51114,Q5SRE5,Q70HW3,Q9UQE7,Q8NC96,Q7KZN9,Q8TD16,P49419,P51530,Q06210,O60885,Q9GZZ9,O00429,Q4J6C6 16 +Ectopia pupillae 0.5295373976664132 0.6703506775881785 0.5026342685129175 1.0 1.0 4 P61586 1 +Overgrowth 0.5288016812372742 0.6675490196506277 0.5044215091361495 1.0 1.0 4 P61978 1 +Epiretinal membrane 0.6016528187803285 0.6643030737737704 0.5064963541283567 1.0 1.0 3 P04439 1 +Cardiovascular calcification 0.4752179803463822 0.6630670853262737 0.5072875898758267 1.0 1.0 8 P42224,P22413,O75431 3 +Exaggerated cupid s bow 0.5098216703339684 0.6625372374750617 0.5076269782779006 1.0 1.0 5 P61978 1 +Abnormality of pancreas physiology 0.3473704183009586 0.6609635052325833 0.508635718084026 1.0 1.0 40 O00330,Q9NZ08,P03886 3 +Elevated circulating long chain fatty acid concentration 0.8089734874235004 0.6595393753050071 0.5095494698526097 1.0 1.0 2 P23786 1 +Hypoplasia of the ear cartilage 0.6000250838361543 0.6585995022679314 0.5101529826002507 1.0 1.0 3 Q9NPF4 1 +Chromosomal breakage induced by ionizing radiation 0.5997959877592819 0.6577978331101836 0.5106680469739615 1.0 1.0 3 Q92878,Q969G3 2 +Increased sensitivity to ionizing radiation 0.5997959877592727 0.6577978331101518 0.5106680469739819 1.0 1.0 3 Q969G3,P49959 2 +Secondary growth hormone deficiency 0.5997959877592698 0.6577978331101415 0.5106680469739886 1.0 1.0 3 O00170,Q969G3 2 +Partial agenesis of the corpus callosum 0.4753247774011213 0.6577039163767774 0.5107284053129684 1.0 1.0 10 O00330,Q15392,Q13509 3 +Peripheral axonal neuropathy 0.326647110015171 0.6570867005757667 0.5111251698757113 1.0 1.0 57 O00330,Q8N9N2,P00846,O95831,Q13509,P07602,P00403,O60524,P03886 9 +Congenital nystagmus 0.4715343818090829 0.6557845971437869 0.5119627282710641 1.0 1.0 16 O75175,P00846 2 +Abnormal nephron morphology 0.3305620940818488 0.6554754004952668 0.5121617195053352 1.0 1.0 60 P35250,Q9NZ08,P00846,P01889,Q12965,P23786,P00403,O75431,Q15056,P03886 10 +Convex nasal ridge 0.460220164843501 0.6554156064755532 0.512200206096316 1.0 1.0 21 Q8NC56,O75312,O60934,Q5SRE5,Q12797,P51530,P18074,P25054,O96028 9 +Abnormal pericardium morphology 0.4748432448039471 0.6545620459617296 0.5127497671576497 1.0 1.0 11 P01889,Q9NZ08,O15460 3 +Melena 0.8072739632902786 0.6541637299953951 0.5130063262004763 1.0 1.0 2 Q02241 1 +Posterior polar cataract 0.8072739632902688 0.6541637299953644 0.513006326200496 1.0 1.0 2 P08670 1 +Hypophosphatemic rickets 0.8069340584636313 0.6530902730855753 0.5136980826678377 1.0 1.0 2 P22413 1 +Specific learning disability 0.3342676764252866 0.6521406727699012 0.5143104279584492 1.0 1.0 63 Q96DF8,P04350,Q9Y2U8,Q13509,Q9Y619,P00403,P35637,O75845,Q06787,Q8N0X7,P03886 11 +Pulmonary infiltrates 0.4709680083825239 0.6490867959885539 0.5162822759442693 1.0 1.0 7 P01889,Q9NZ08 2 +Breast carcinoma 0.4643541531287227 0.648731051678612 0.5165122299907126 1.0 1.0 19 P21912,P43246,Q92878,O60934,O75874,O75330,P21359,P48735,P25054,Q07864,P42771 11 +Gowers sign 0.473268042510272 0.6476437242056142 0.5172154102538069 1.0 1.0 12 Q9BUK6,Q8TD16 2 +Dysmetric saccades 0.4706217186165753 0.6475570640669444 0.5172714751302672 1.0 1.0 7 O95140,Q9NW15,P49959,O15020 4 +Coxa vara 0.4722511987209775 0.6446492191098427 0.5191545312443409 1.0 1.0 13 Q96AY3,Q96HY6,O95831 3 +Delayed cns myelination 0.406482041311073 0.6434792445421798 0.5199131782091133 1.0 1.0 32 Q9Y5S9,Q5SRE5,O95831,Q15042,O75175,P49419 6 +Ovarian cyst 0.4709048545235111 0.6414576471396367 0.5212253894543446 1.0 1.0 14 P16435,P35250,P21912,P78347,P10644,Q15056,Q03252,P02545,P31751 9 +Abnormality of peripheral nerves 0.3350330595082595 0.6323817921523984 0.5271374287599706 1.0 1.0 41 Q99720,P07602,O95831,Q9Y619 4 +Colitis 0.4692110378536792 0.6323727771014114 0.5271433181571428 1.0 1.0 9 Q15477,O95999,Q6PGP7,P42224 4 +Abnormal t cell subset distribution 0.4700291255256715 0.6323208987776652 0.5271772101380257 1.0 1.0 11 O14920,O95999,P17812 3 +Migraine 0.4569813192623667 0.6232803962210931 0.53310027793139 1.0 1.0 20 P00403,Q9NZ08,P03886 3 +Abnormal circulating lipid concentration 0.3431660640760744 0.6227320255415816 0.5334606336861043 1.0 1.0 72 P35250,P28070,Q16836,Q15392,Q8N511,Q15800,O43772,Q15056,P23786,P11310,P07602,Q4G0N4,O75431,P34913,O75845,Q03252,P50402,P31751 18 +Distal amyotrophy 0.3231206755799811 0.6224902961155538 0.5336195226063789 1.0 1.0 57 Q99720,O60524,Q8TD16,P35637,Q9BUK6,Q7Z406,Q9BQT8,Q8N0X7 8 +Polygenic inheritance 0.4625839093820856 0.6188301856361036 0.5360282343767993 1.0 1.0 6 O60934 1 +Tissue ischemia 0.4585627220041638 0.6187921061525172 0.5360533231554063 1.0 1.0 19 P22413,Q9NZ08,P01889,O15460,Q15056 5 +Sagittal craniosynostosis 0.4619518603397834 0.6160965777613658 0.5378307806172753 1.0 1.0 6 P61978,P21281 2 +Abnormally lax or hyperextensible skin 0.3507546237631971 0.6160319468320211 0.5378734351752814 1.0 1.0 39 Q9NWM8,O96000,Q15056,A2RRP1 4 +Aplasia hypoplasia involving the pelvis 0.4664751563405881 0.6160043227005462 0.5378916668271216 1.0 1.0 11 Q5H8A4,Q96HY6,O95831 3 +Brisk reflexes 0.4461785188801468 0.6144429539554421 0.5389226587378131 1.0 1.0 23 Q99720,Q5JRX3,Q9BSJ2,Q01082,P35637,P20674,Q9NW15 7 +Ileus 0.5869266914247475 0.6132131046377581 0.5397354408900539 1.0 1.0 3 Q01844 1 +Abnormal thrombosis 0.4420216456844227 0.6116121695310597 0.5407943845476473 1.0 1.0 24 Q9NZ08,P01889,O75874,Q6UN15,O15460,P48735,Q96AA3 7 +Viral encephalitis 0.7933378653976901 0.6106259213561858 0.5414472580544856 1.0 1.0 2 Q9Y4L1 1 +Abnormal circulating methionine concentration 0.4602668388740773 0.6088223243089141 0.5426422146221295 1.0 1.0 6 P16930,P55263,Q6PGP7 3 +Premature rupture of membranes 0.4601769911504287 0.6084350058554749 0.5428990002102452 1.0 1.0 6 Q8NC56,P50454,Q9Y487,O75844,P02545 5 +Pancreatitis 0.4539532499685194 0.6074507296599398 0.5435518309560317 1.0 1.0 20 P01889,P00403,Q9NZ08,P03886 4 +Pierre robin sequence 0.4613868704926407 0.6070528801103159 0.5438158193615583 1.0 1.0 7 Q96DF8 1 +Glucose intolerance 0.3714404170740856 0.6028218796858438 0.5466271897008004 1.0 1.0 96 P35250,P00846,Q9Y2U8,O96000,Q03252,P03886,O00330,P61457,O43676,Q9NPL8,Q06787,Q92620,P00403,O75431,O43837,Q5JRA6,P31751,O00429,P22413,O43172,Q8IUX1,Q15056 22 +Erythroderma 0.4602385409007749 0.6020572992173893 0.5471359969087615 1.0 1.0 7 P48449 1 +Abnormality of the glabella 0.4597234189321082 0.5998194469752552 0.5486265714374239 1.0 1.0 7 Q01082,A2RRP1,P21359 3 +Shallow orbits 0.4605852618451586 0.59811356010038 0.5497641628941623 1.0 1.0 8 Q8NC56,P02545,P61978,O75431 4 +Stroke 0.4115258452400523 0.5978743703491283 0.5499237623746343 1.0 1.0 30 P22413,O95235,P00403,Q15056,Q96AA3,P03886 6 +Missing ribs 0.462174115159794 0.5963812665714044 0.550920552335328 1.0 1.0 11 Q96T58,Q12768 2 +Acanthosis nigricans 0.4612382044297871 0.5938036616878427 0.5526434396869169 1.0 1.0 10 P28070,Q96MF7,Q13620,O75431,P31751 5 +Memory impairment 0.38559000442863 0.5904581712099608 0.5548835209567891 1.0 1.0 34 Q9NZ08,P07602,P00403,Q06787,P03886 5 +Bird like facies 0.4913886975757618 0.5899259182522796 0.5552403169516684 1.0 1.0 5 Q92878,P18074 2 +Temporal pattern 0.4554890690723665 0.5883062241121209 0.5563267686161555 1.0 1.0 6 Q12768,P11182 2 +Aortic arch aneurysm 0.4583291655237027 0.5882324527985665 0.5563762773052157 1.0 1.0 8 Q96T58,Q15056 2 +Abnormality of the alveolar ridges 0.4546489722422094 0.5847160408638554 0.5587386663668736 1.0 1.0 6 Q15392,P21281 2 +Neoplasm of the breast 0.4395480116747668 0.5780847431302207 0.5632069070510126 1.0 1.0 23 P21912,P43246,Q92878,O60934,O75874,P42771,O75330,P21359,P48735,P10644,P25054,P02545,Q07864 13 +Gastrostomy tube feeding in infancy 0.4136600729856215 0.5773440544201409 0.5637070590806708 1.0 1.0 29 Q99720,Q01105,P35637 3 +Muscular ventricular septal defect 0.5743980209784422 0.5707216368593043 0.5681883495760347 1.0 1.0 3 Q5SRE5 1 +Paroxysmal involuntary eye movements 0.4490699279873076 0.570331557706731 0.5684528407859264 1.0 1.0 19 O96000,P03886 2 +Shawl scrotum 0.4858993715775164 0.5687311395508657 0.5695386120090697 1.0 1.0 5 Q9Y619 1 +Gynecomastia 0.4514908982861392 0.5643246660504329 0.5725331976611541 1.0 1.0 17 Q9Y4W2,Q8WWQ0,P21912,Q8IWS0,Q01082,Q13620,Q06787,P31751 8 +Abnormal lymphocyte morphology 0.3881693956831343 0.5626431843728785 0.5736778796456354 1.0 1.0 33 Q13432,Q15477,P28070,O95999,O60934,O14920,P33991,P17812,Q03252 9 +Tongue fasciculations 0.4544229248856067 0.5606511278022562 0.5750353899016369 1.0 1.0 12 P51114,Q9BQT8,O95831 3 +Short foot 0.4288906150409936 0.5594554213716396 0.5758509468208342 1.0 1.0 25 Q96T58,Q10471,O60885,Q93009,Q13620,Q9UQE7,Q13509,Q14320,Q13555,O60216,Q06787,Q8N0X7,Q08J23 13 +Abnormality of complement system 0.5700240198028464 0.5561177572870765 0.5781303566769296 1.0 1.0 3 Q03252 1 +Temporal optic disc pallor 0.775322909585318 0.5558909488136118 0.5782854061361369 1.0 1.0 2 O00429 1 +Morning glory anomaly 0.775322909585318 0.5558909488136118 0.5782854061361369 1.0 1.0 2 O00429 1 +Anomalous trichromacy 0.775322909585318 0.5558909488136118 0.5782854061361369 1.0 1.0 2 O00429 1 +Tritanomaly 0.775322909585318 0.5558909488136118 0.5782854061361369 1.0 1.0 2 O00429 1 +Paresthesia 0.4479915550261479 0.5551682456869558 0.5787795865151444 1.0 1.0 18 Q9NZ08,O15460,P54802 3 +Abnormal pancreas morphology 0.4508020822605912 0.5545253361878428 0.5792193711413505 1.0 1.0 16 Q96T58,O00330,Q9Y5S9 3 +Prominent nasal bridge 0.3512291373005251 0.5540129222327907 0.5795700021139605 1.0 1.0 38 Q96T58,P78318,Q9H2M9,O60934,Q9Y2U8,Q5JRA6,Q8WVM7 7 +Tapered finger 0.3986179635496701 0.5515570882817248 0.5812518434731446 1.0 1.0 31 Q96T58,Q8WWQ0,Q03164 3 +Chorioretinal coloboma 0.4809475000084406 0.5497981753417694 0.5824578103117592 1.0 1.0 5 Q12768 1 +Large face 0.313654000039124 0.5439456078317988 0.5864789029636142 1.0 1.0 56 Q96T58,A2RRP1,Q92643,Q6PJG6,Q9BUK6,O75175,Q06787,P61978 8 +Cns hypomyelination 0.3333773162708078 0.5421770005588135 0.5876965777785594 1.0 1.0 40 Q99720,P35637 2 +Progressive visual loss 0.4359153978922302 0.5416594718055253 0.5880531140713119 1.0 1.0 22 P00846 1 +Aortic aneurysm 0.300949696774524 0.540322390708857 0.5889747195473216 1.0 1.0 47 Q96T58,P35250,P01889,O15460,Q15056,O75175,Q06787,P61978 8 +Recurrent mycobacterial infections 0.7698844323589417 0.539738031026446 0.5893777084443359 1.0 1.0 2 P42224 1 +Polar cataract 0.5648690022350382 0.5390689286678852 0.5898392940946413 1.0 1.0 3 P08670 1 +Fibrous tissue neoplasm 0.4445430686266539 0.5381554829374071 0.5904697107977652 1.0 1.0 18 Q15392,P21912,P43246,Q01082,Q13126,P21359,P21281,P10644,P25054,P16220 10 +Abnormality of the temporomandibular joint 0.4937239709530484 0.5379139008588122 0.5906364910791957 1.0 1.0 4 P08754,P02545 2 +Abnormal dura mater morphology 0.5644338660319667 0.5376381042158417 0.5908269184609904 1.0 1.0 3 Q9UMX1,Q8N3U4 2 +Cyclopia 0.5644338660319667 0.5376381042158417 0.5908269184609904 1.0 1.0 3 Q9UMX1,Q8N3U4 2 +Panhypopituitarism 0.5644338660319667 0.5376381042158417 0.5908269184609904 1.0 1.0 3 Q9UMX1,Q8N3U4 2 +Nuclear cataract 0.4771994301378289 0.5355912858345161 0.5922410526114894 1.0 1.0 5 P08670 1 +Progressive external ophthalmoplegia 0.4486283407881026 0.5355479501941692 0.5922710097198876 1.0 1.0 11 P00403,P03886,P51530 3 +Entropion 0.4450336433477423 0.5308220901405097 0.5955420707776959 1.0 1.0 8 P01889,P36543,P18074 3 +Rotary nystagmus 0.4911564625850292 0.528768714153161 0.5969659033047074 1.0 1.0 4 Q14738,Q5T8D3,Q9Y4R8 3 +Hypermethioninemia 0.4749398737818564 0.5270798191628898 0.5981381603735716 1.0 1.0 5 P55263,Q6PGP7 2 +Raynaud phenomenon 0.4722694794147721 0.5170739146028226 0.6051045622407101 1.0 1.0 5 Q14739,P55265,O75792,P02545 4 +Early onset of sexual maturation 0.346228905761614 0.5150542838489991 0.6065150874797398 1.0 1.0 38 Q96T58,O75874,P48735,Q15056,Q5JRA6 5 +Abnormal social behavior 0.3185501461312408 0.5138618631502182 0.6073485725331207 1.0 1.0 62 Q96T58,P35250,O43676,Q9Y3C6,Q01082,Q13509,P07602,Q9NPL8,O96000,P18074,Q15056,Q06787,Q9GZZ9,P03886 14 +Long palpebral fissure 0.4352532580221981 0.5116115173262683 0.6089229232420894 1.0 1.0 20 Q96T58,Q01082,P61978,Q8WXI9 4 +Abnormal form of the vertebral bodies 0.3391534698278072 0.5114173245961738 0.6090588663215541 1.0 1.0 78 P82673,O75845,Q5H8A4,P22413,Q12768,O75874,O95831,Q96AY3,Q5JRA6,Q9Y619,P48735,P21281,Q15056,P54802,Q32P28,Q96HY6 16 +Cardiac arrest 0.397707095516576 0.5111370722764851 0.6092550785354072 1.0 1.0 30 P35250,P22413,P01889,Q9H2M9,O43772,O15460,Q15056 7 +Abnormal growth hormone level 0.4270842786717191 0.5109878927054627 0.6093595346441472 1.0 1.0 23 Q03164,Q4J6C6 2 +Abnormal visual electrophysiology 0.2991600489391728 0.5097624671486354 0.6102178835310434 1.0 1.0 48 P00846,Q13724,Q9H2M9,Q92620,P07602,Q15042,Q96S66,O43837 8 +Abnormal adipose tissue morphology 0.3043655180250084 0.5071209866460347 0.6120699304930752 1.0 1.0 52 P22413,P28070,Q8NC56,P09493,P25054,Q9Y2U8,O75431,P31751,P18074,Q9BUK6,Q03252,P50402,P36543 13 +Skin dimple 0.4113436229309746 0.5065575688666073 0.6124652866505391 1.0 1.0 27 P35250,Q5H8A4,Q03164,Q15056,P61978,Q08J23 6 +Cardiomegaly 0.3857580760474671 0.5059587485458003 0.6128856088515637 1.0 1.0 32 P35250,P22413,Q07021,Q13724,P23786,P11310,Q15056,P54802 8 +Thoracolumbar scoliosis 0.4355191912288561 0.5045055957511836 0.6139061309372218 1.0 1.0 6 P78318 1 +Focal t2 hyperintense basal ganglia lesion 0.4309770781883683 0.5019359409211036 0.6157125824911072 1.0 1.0 21 P00846 1 +Hyporeflexia 0.3735117756272072 0.500105440469433 0.6170008355425038 1.0 1.0 107 Q99720,P00846,P07602,Q9BUK6,P54802,P35610,P03886,O14979,O95831,P21281,P18074,Q7Z406,Q06787,Q5H8A4,Q8NC96,Q8TD16,P35637,Q9GZZ9,P11177 19 +Calvarial hyperostosis 0.4672008337574244 0.498245249571711 0.6183111925726887 1.0 1.0 5 Q15043,P22626,P10644 3 +Limb dysmetria 0.7545887151597409 0.4953047071121295 0.6203850487478846 1.0 1.0 2 Q12768 1 +Wide intermamillary distance 0.4335477771853236 0.4929857570730908 0.6220226511736573 1.0 1.0 19 Q8WWQ0,Q5SRE5,P23786 3 +Generalized muscle weakness 0.3947048318691727 0.492649359836052 0.6222603648206919 1.0 1.0 30 Q15165,O95831,Q5JTZ9,Q92804,P35637 5 +Gonadal dysgenesis 0.4369954966764394 0.4916384973727596 0.6229749233863637 1.0 1.0 9 P18074 1 +Decreased circulating igg level 0.436833874204344 0.490955565584949 0.6234578753667366 1.0 1.0 9 P17812,Q13724 2 +Abnormal platelet volume 0.4355727168402512 0.4909117408936601 0.6234888726048673 1.0 1.0 8 O75845,Q15477 2 +Abnormal nerve conduction velocity 0.3427996927516342 0.4886330559031501 0.6251015060127156 1.0 1.0 38 Q99720,P07602,O95831,Q9Y619 4 +Generalized hyperkeratosis 0.4796482984376596 0.4884438849431204 0.6252354638206623 1.0 1.0 4 P02545 1 +Limb joint contracture 0.3478446156898013 0.4869510313626921 0.6262930335992856 1.0 1.0 87 Q99720,O00330,Q15392,Q96T58,Q96AY3,Q13509,P23786,Q9Y619,Q8TD16,Q15042,P35637,Q08J23 12 +Abnormality of the ribs 0.3142412196707905 0.4858622026800251 0.6270648685289388 1.0 1.0 61 Q96T58,Q5H8A4,Q9Y5S9,Q12768,O95831,Q03164,Q9Y619,P21281,P54802,Q32P28,Q96HY6 11 +Bilateral ptosis 0.4375262957686112 0.4857136977147906 0.6271701704933119 1.0 1.0 14 O00330,Q13509,O60313,P21281,O00429 5 +Hypotelorism 0.3764997835195364 0.4844546075007772 0.6280632717520196 1.0 1.0 33 Q9H2M9,Q15042,Q9BUK6,O75175,Q08J23 5 +Chromosome breakage 0.4339234843269476 0.4840422880720099 0.6283558577763866 1.0 1.0 8 Q06787,P33991 2 +Velopharyngeal insufficiency 0.4780124363888388 0.4828041991953711 0.6292347689365243 1.0 1.0 4 Q96DF8 1 +Male reproductive system neoplasm 0.4367058796926292 0.4820192424696184 0.6297922768419066 1.0 1.0 14 Q01844,Q92878,O60934,Q9UPY3,P10644,P25054 6 +Abnormal oral mucosa morphology 0.3083283731608477 0.4805837988344668 0.6308123322621046 1.0 1.0 57 Q15392,Q9NZ08,Q92990,P01889,Q6UN15,Q02241,O75431,P21281,O75845,Q5JRA6,Q15056 11 +Asthma 0.4309232008511896 0.4801697565732271 0.6311066899833044 1.0 1.0 19 Q5JRA6,Q9UID3,Q08J23,Q9UJV9 4 +Decreased testicular size 0.4306818814218393 0.4789954812101747 0.6319418433519259 1.0 1.0 19 Q8WWQ0,Q9UPP1,O75312,Q8IWS0,Q13620,Q9NP72,O15294,P18074,Q06787,O43505,O60828 11 +Fibrosarcoma 0.5455338267636733 0.476813735849711 0.633494763721197 1.0 1.0 3 Q13126 1 +Wormian bones 0.4340191795999745 0.4754526409438168 0.6344643814635795 1.0 1.0 16 Q32P28,O95831 2 +Abnormality of neutrophil morphology 0.4758503401360445 0.4753870999805398 0.6345110874320636 1.0 1.0 4 O75533,P35579,P62263 3 +Arthrogryposis multiplex congenita 0.3483298171986364 0.4741782871025275 0.6353727755228995 1.0 1.0 37 O00330,Q8N9N2,Q15392,Q96AY3,Q8TD16,Q96AA3 6 +Unusual infection by anatomical site 0.4348652686259832 0.4737574839074828 0.6356728561266003 1.0 1.0 14 Q9NZ08,O95999,P01889,Q9Y4L1,O15460 5 +Impaired distal vibration sensation 0.4603172834766486 0.4730333607236774 0.6361893784658115 1.0 1.0 5 Q06787 1 +Irritability 0.3310845942890271 0.4723444466394229 0.6366809501609969 1.0 1.0 75 Q9NZ08,P00846,P61457,O43772,O95831,P07602,Q06787,P49419 8 +Dementia 0.3059752127502732 0.4711275825316429 0.6375496290948448 1.0 1.0 56 P00846,P04350,P07602,P00403,P35637,P03886 6 +Abnormal peripheral myelination 0.3854240092489896 0.4680543965536453 0.6397456900776566 1.0 1.0 31 P03886,P00846 2 +Abnormal morphology of the limbic system 0.4330689588173667 0.4677476423884183 0.6399650666198973 1.0 1.0 11 Q01105,Q13509 2 +Polysplenia 0.5423437583217624 0.4668170684713413 0.6406307630328782 1.0 1.0 3 Q9ULC3 1 +Dysuria 0.4293949358575634 0.4653213934210566 0.6417013166929382 1.0 1.0 8 P01889 1 +Open mouth 0.4038547224700538 0.4638423293173176 0.6427607137670965 1.0 1.0 27 Q96DF8,P04350,P61978,Q03001 4 +Abnormal t cell morphology 0.4322903226269023 0.4622630013438876 0.6438927286233154 1.0 1.0 14 O60934,O14920,O95999,P17812 4 +Adipose tissue loss 0.42688905496967 0.4617093490797233 0.6442897657648938 1.0 1.0 7 O75431,P18074 2 +Abnormal renal cortex morphology 0.3007371826689031 0.4600046660208762 0.6455128713251093 1.0 1.0 53 P03886,Q9NZ08,P00846 3 +Abnormality of corneal size 0.360180547303464 0.459842169508146 0.6456295122750924 1.0 1.0 35 P35250,Q5H8A4,Q9H2M9,Q9ULC3,Q9UQE7,Q9NP72,Q15042,P18074,O75845,Q15056,Q9NWM8 11 +Pseudoarthrosis 0.470731575081777 0.457998133302033 0.6469537823785214 1.0 1.0 4 P21359 1 +Increased urine alpha ketoglutarate concentration 0.470657978722575 0.4577499067110464 0.6471321285309783 1.0 1.0 4 P21912,P21281 2 +Thoracic scoliosis 0.4298332376270654 0.4572319138561586 0.6475043619472256 1.0 1.0 10 Q13724 1 +Intractable diarrhea 0.5387223517830335 0.4555689714603348 0.6486999598950702 1.0 1.0 3 Q15477 1 +Abnormality of upper limb epiphysis morphology 0.4305612709097738 0.4541524675672708 0.649719091842085 1.0 1.0 13 P82673,Q9ULC3,P10644,O96028,Q5JRA6 5 +Long toe 0.4266640765246219 0.4485253143912854 0.6537741209312053 1.0 1.0 9 Q8WXI9 1 +Deviated nasal septum 0.7372535690006827 0.4468571846347491 0.6549781794144178 1.0 1.0 2 P21359 1 +Depression 0.3470828160317799 0.4463548609446067 0.6553409334011913 1.0 1.0 90 Q8WWQ0,O60524,Q15165,P35250,P01889,P07602,P00403,Q92804,O15460,Q5JTZ9,P51530,P35637,Q9BUK6,P50995,Q06787,Q15056,P03886,Q08J23 18 +Aplasia hypoplasia of the nipples 0.4276701297141231 0.4463472606433878 0.6553464225977208 1.0 1.0 16 Q5H8A4,P10586,Q12768,Q9UQE7,O60216,O60885 6 +Shoulder girdle muscle weakness 0.4279716888048263 0.4460848252845402 0.6555359737775392 1.0 1.0 11 Q8TD16,P07602,O14979 3 +Decreased circulating copper concentration 0.7369136641740341 0.4459287406852993 0.6556487207114583 1.0 1.0 2 Q10567 1 +Focal segmental glomerulosclerosis 0.4192351033222565 0.4429586240265155 0.6577956626814083 1.0 1.0 21 Q8N1F7,Q8NFH4,Q12965,P00403,O75431,P03886 6 +Hyperammonemia 0.3576648441407284 0.4425226694681604 0.6581110296734598 1.0 1.0 35 A2RRP1,O43772,P23786,P11310,Q9Y619,P35610 6 +Abnormality of small intestinal villus morphology 0.4200268196736503 0.4420179039187868 0.6584762501433681 1.0 1.0 6 Q15477,Q6PGP7,P42224 3 +Abnormality of the ankles 0.2954169476398102 0.4400053478628519 0.6599332340303743 1.0 1.0 43 P35250,Q9H2M9,O75298,Q96AY3,P07602,Q15056,Q8N0X7,Q9NW15 8 +High hypermetropia 0.4243145867477333 0.4388813723664934 0.660747494743674 1.0 1.0 9 Q96T58,Q15056 2 +Abnormal elasticity of skin 0.3024303417346079 0.438127281702658 0.6612940187370697 1.0 1.0 56 Q96T58,P22413,A2RRP1,O96000,Q9UQ13,P21281,Q15056,Q9NWM8,Q15334 9 +Communicating hydrocephalus 0.4636054421768707 0.4342056676712103 0.6641390977604431 1.0 1.0 4 P07237,Q9NRZ9,O00754 3 +Suicidal ideation 0.7324949014275963 0.43393708849575 0.6643341262046067 1.0 1.0 2 Q01082 1 +Hypoplastic female external genitalia 0.4253138029198243 0.43290210048229 0.6650858939771105 1.0 1.0 15 Q9H2M9,Q9UQE7,Q9Y619,Q9NP72,Q15042 5 +Skin ulcer 0.3894147458950761 0.4316041118113842 0.666029169470344 1.0 1.0 29 O15460,O75874,P48735 3 +Supraventricular arrhythmia 0.424959079910198 0.4299594215797971 0.667225159295052 1.0 1.0 14 O95235,P00846 2 +Apnea 0.3353068269238913 0.4299292947484274 0.6672470748959742 1.0 1.0 82 P00846,Q13724,O43772,P51114,Q9UID3,P23786,Q03001,Q6PJG6,P07602,Q4G0N4,P51530,Q9Y263,P03886 13 +High pitched voice 0.421899151304045 0.4290319776167386 0.6678999534681367 1.0 1.0 9 Q9Y6X9,O75431,P28340,P07237,Q06787,P02545 6 +Abnormal retinal artery morphology 0.4139656266264093 0.4287135394846793 0.6681317061857088 1.0 1.0 22 Q15056,P03886,P00846 3 +Carcinoid tumor 0.729775662814415 0.4266306014001764 0.6696484051472136 1.0 1.0 2 P25054 1 +Xanthomatosis 0.7297756628143983 0.4266306014001307 0.6696484051472469 1.0 1.0 2 P34913 1 +Squamous cell carcinoma of the skin 0.7297756628143983 0.4266306014001307 0.6696484051472469 1.0 1.0 2 P18074 1 +Choreoathetosis 0.3837363621943267 0.4263580199111085 0.6698469862426943 1.0 1.0 30 P04350,P00846,P18074 3 +Peripheral pulmonary artery stenosis 0.4211262722425354 0.4258946406651415 0.6701846203005519 1.0 1.0 9 Q15056,Q15477,P35250 3 +Cloverleaf skull 0.7280761386811726 0.4220926888796448 0.6729573641855091 1.0 1.0 2 Q9ULC3 1 +Abnormal circulating aspartate family amino acid concentration 0.4185988146205722 0.4215784034723533 0.673332772548985 1.0 1.0 8 P16930,Q4G0N4,P55263,Q6PGP7 4 +Abnormal circulating dicarboxylic acid concentration 0.3263524569040983 0.4209477181137876 0.6737932594680491 1.0 1.0 39 Q9Y5L0,Q4G176,Q01082,P55263,Q9UGP8,P23786,Q02241,P40855,P48735,O75845 10 +Hypotension 0.4034399633724024 0.4202529872902265 0.6743006498892421 1.0 1.0 25 O43772,P07602,P35610 3 +Dystrophic toenail 0.4453895882953494 0.4198962944277306 0.6745612148952773 1.0 1.0 5 P51149,O75844,P02545,Q969G3 4 +Anhidrosis 0.4453895882953401 0.419896294427699 0.6745612148953004 1.0 1.0 5 P20700,P04066,Q9Y276,O15270 4 +Progressive sensorineural hearing impairment 0.4225850409066459 0.4197238002764845 0.6746872362958674 1.0 1.0 13 P00403,P03886 2 +Abnormality of retinal pigmentation 0.3185473718846668 0.4167975280657891 0.6768265106642399 1.0 1.0 70 Q13432,Q16836,Q8WWY3,P00846,Q96CU9,Q9H2M9,Q15042,Q96S66,Q9BUK6,P03886,Q9NP72,P40855,Q15067,P18074,P25054,Q9P0J0,Q92620,P00403,O43837,P24386,O43172,Q7KZN9,Q6P4Q7 23 +Micromelia 0.4114543767087927 0.4162042375000938 0.6772605592229564 1.0 1.0 22 Q15392,O75874,P48735 3 +Squamous cell carcinoma 0.4207688679207069 0.4159826906612506 0.6774226693319367 1.0 1.0 11 P42224,P18074,O60885,P02545,Q03426,P42771 6 +Abnormal circulating igg level 0.4205888065264351 0.4152381405915132 0.6779675804646677 1.0 1.0 11 P17812,Q13724 2 +Delayed ability to sit 0.4191597626203455 0.4118111026666288 0.6804778829165952 1.0 1.0 17 Q9H2M9,Q9UID3,Q13509 3 +Hypogonadism 0.3295046495004233 0.4118011456318673 0.6804851816134412 1.0 1.0 79 Q96T58,Q8WWQ0,O43172,Q9H2M9,P48449,Q92620,P00403,Q15042,P18074,Q15056,O43837,Q06787,P03886,Q4J6C6 14 +Streak ovary 0.4430078257910866 0.4116264935371074 0.6806132098038074 1.0 1.0 5 Q8IY37,P82650,P57740,P51809 4 +Papule 0.4186895511105619 0.409686449828135 0.682035971232561 1.0 1.0 17 P01889,Q9NZ08,Q92990 3 +Elevated pulmonary artery pressure 0.4073252694604919 0.4086226359395256 0.6828166163301004 1.0 1.0 23 P22413,P01889,P00403,O96000,P03886,P20674 6 +Severe muscular hypotonia 0.3891769638350907 0.4048940197994367 0.685555414368598 1.0 1.0 28 Q5H8A4,Q8N9N2,O95831,Q8TD16,Q01105,Q9NWM8 6 +Fasciculations 0.3314266886303613 0.4029750142877053 0.6869666054143664 1.0 1.0 38 P51114,Q5THJ4,Q9NWS8,O95831,P07602,Q8TD16,P35637,Q9BQT8,Q9NW15 9 +Brachycephaly 0.3065428773017961 0.4027383912262549 0.6871406880842961 1.0 1.0 62 Q96T58,Q9Y5S9,A2RRP1,O60885,Q9H2M9,Q12768,Q9ULC3,Q9UQE7,Q96AY3,Q9NP72,Q15042,O75431,P21281,O75179,O75175 15 +Dehydration 0.4167102874067548 0.4007764444058361 0.6885847230540627 1.0 1.0 17 P82673,O00330 2 +Sparse eyebrow 0.3792824314708688 0.4000535922929912 0.6891170443199379 1.0 1.0 30 Q5SRE5,Q92643,P48449,P61978,Q08J23 5 +Telangiectasia 0.3740626703272008 0.3985405577394887 0.6902317682327299 1.0 1.0 31 P03886,P00846 2 +Thin eyebrow 0.4174055076435513 0.3973727125589181 0.6910926347511335 1.0 1.0 14 P48449 1 +Abnormality of the thyroid gland 0.3510664570452617 0.3953464623464899 0.6925872143175043 1.0 1.0 98 P35250,Q9UNW1,P48735,Q9BUK6,P03886,P61978,Q15477,O75874,P21281,Q06787,Q07021,Q13724,P00403,Q9UPY3,Q96T58,Q8WWQ0,P22413,O95999,Q15056,Q9Y263 20 +Symphalangism of middle phalanx of finger 0.7178789938817165 0.3953385010389539 0.6925930890120009 1.0 1.0 2 Q15233 1 +Abnormal cardiac ventricular function 0.4154128588769367 0.3949654311976768 0.6928684001168071 1.0 1.0 17 O95235,P00403,P03886 3 +Rectal prolapse 0.4118526691937302 0.3949277894563254 0.69289618051891 1.0 1.0 8 Q15056,Q08J23 2 +Phenotypic variability 0.3484288129793256 0.3933368612110779 0.6940706964172283 1.0 1.0 96 O00330,P00846,O14979,P04350,Q5THJ4,Q70HW3,Q13509,Q8TD16,P00403,P07602,Q9UJV9,P50995,Q92733,Q9Y263,Q06787,P03886 16 +Glomus jugular tumor 0.7165193745751224 0.3918338114422016 0.6951810107610108 1.0 1.0 2 P21359 1 +Bone cyst 0.7165193745751224 0.3918338114422016 0.6951810107610108 1.0 1.0 2 P21359 1 +Follicular thyroid carcinoma 0.7165193745751142 0.3918338114421802 0.6951810107610266 1.0 1.0 2 Q9UNW1 1 +B cell lymphoma 0.4499686644497199 0.3901145339174673 0.6964518560996142 1.0 1.0 4 O60934 1 +Adenocarcinoma of the small intestine 0.7158395649218252 0.3900870838973255 0.6964721533662499 1.0 1.0 2 P25054 1 +Duodenal adenocarcinoma 0.7158395649218252 0.3900870838973255 0.6964721533662499 1.0 1.0 2 P25054 1 +Hypoplastic nipples 0.4132384004727894 0.3892196913622044 0.6971136380864082 1.0 1.0 10 O60885,P10586,Q9UQE7 3 +Vertebral segmentation defect 0.3719909817436895 0.3861368296891644 0.6993953348808688 1.0 1.0 31 P35250,Q9Y5S9,P22413,Q12768,Q9Y619,P21281,Q15056,P61978 8 +Extramedullary hematopoiesis 0.5153315554649218 0.3856628061490432 0.6997464121319559 1.0 1.0 3 P98175 1 +Submucous cleft of soft and hard palate 0.3993437883765329 0.3826888076129908 0.7019505141187314 1.0 1.0 24 Q9Y619,Q96DF8,Q15392 3 +Abnormality of the breast 0.3409976145081932 0.3814662614700271 0.7028573014415103 1.0 1.0 91 Q9H2M9,Q12768,Q01082,P48735,P61978,Q92878,O60934,O75874,Q9NP72,P18074,Q06787,Q5H8A4,P10586,Q5SRE5,Q9UQE7,P31751,Q8WWQ0,P23786,Q9Y619,Q96AA3 20 +Abnormal left atrium morphology 0.5137799879623943 0.381204222874194 0.7030517158810432 1.0 1.0 3 O95235 1 +Left atrial enlargement 0.5137799879623943 0.381204222874194 0.7030517158810432 1.0 1.0 3 O95235 1 +Hemivertebrae 0.4128450491608719 0.3806295215195955 0.7034781723629735 1.0 1.0 12 Q9Y619,Q12768 2 +Tetralogy of fallot 0.3131498760099318 0.3783108187715048 0.7051997094027693 1.0 1.0 40 Q96T58,Q15477,P35250,Q9Y5S9,Q96DF8,Q6PGP7,Q8TAQ2,Q12768,Q9ULC3,Q69YQ0,Q15056 11 +Abnormality of bladder morphology 0.4114179319292649 0.377859021842244 0.705535325300291 1.0 1.0 11 Q15056,Q9NWM8 2 +Porencephalic cyst 0.4452380952380913 0.3752881408663483 0.7074461849367912 1.0 1.0 4 O75792,P55265,Q06330 3 +Generalized hirsutism 0.399062071301312 0.3675415438583167 0.7132151093359096 1.0 1.0 23 Q96T58,Q9H2M9,Q9UQE7,Q03164,Q9NP72,Q15042,Q03252 7 +Moderately reduced visual acuity 0.50870633956992 0.3667889045433619 0.7137764845942742 1.0 1.0 3 O00429 1 +Abnormal endocardium morphology 0.4097712205699882 0.3655159840145874 0.7147262774849161 1.0 1.0 15 P01889,P22413,Q9NZ08,Q15056 4 +Pseudoepiphyses of hand bones 0.4288832591639294 0.3638647246378498 0.7159590272764222 1.0 1.0 5 Q9ULC3 1 +Pseudoepiphyses 0.4288832591639294 0.3638647246378498 0.7159590272764222 1.0 1.0 5 Q9ULC3 1 +Limb ataxia 0.400384538944696 0.3622245216718119 0.7171842563738164 1.0 1.0 22 Q12768,O75298,Q5THJ4,Q9BUK6,Q9NW15 5 +Low posterior hairline 0.3516773691873437 0.3618901091252207 0.7174341514897851 1.0 1.0 34 Q5H8A4,Q9UPP1,O60885,Q9H2M9,Q12768,P25054,Q9UID3,Q9UQE7,Q9Y2W2,P21359,Q15042,Q9UQ13,O60216,O75175 14 +Abnormal circulating hormone concentration 0.3225557620303096 0.3615009503671903 0.7177249946613138 1.0 1.0 78 O00330,Q8WWQ0,Q16836,Q12768,Q03164,Q92620,O75431,O43837,Q06787,P31751,Q4J6C6 11 +Abnormality of the basal ganglia 0.3200218398781761 0.3614870571682492 0.7177353786921086 1.0 1.0 76 O00330,P00846,O95831,Q13509,P23786,Q4G0N4,P00403,O60524,Q96AA3,P03886,Q08J23 11 +Fibroadenoma of the breast 0.5064009809930503 0.3603234234341712 0.7186052847439053 1.0 1.0 3 P25054 1 +Aplasia hypoplasia involving bones of the feet 0.3004194491246408 0.3596558623224966 0.7191045029559533 1.0 1.0 61 Q10471,Q9H2M9,Q03164,Q13555,O75175,Q8N0X7,P02545,Q08J23,P21281,P10644,P25054,O60216,Q06787,Q5H8A4,Q9ULC3,Q13620,Q9UQE7,Q9Y296,O60885,O96028,Q5JRA6,Q96T58,Q8IWS0,Q13509,Q69YQ0,Q14320 26 +Vascular calcification 0.4268236323824806 0.3570919220874884 0.721022991606374 1.0 1.0 5 P22413 1 +Dyskinesia 0.2972956261204092 0.3553510368514974 0.7223266251589568 1.0 1.0 59 P00846,Q8NC96,Q01105,O60524,P35610,P03886,Q08J23 7 +Amaurosis fugax 0.4014324925669079 0.3548888376764349 0.7226728711460071 1.0 1.0 8 O15460 1 +Decreased activity of mitochondrial complex i 0.3505734523619221 0.3548601817402536 0.7226943399586387 1.0 1.0 34 O96000,Q70HW3,P03886 3 +Vertigo 0.3907282670631887 0.3544141501341788 0.7230285316302656 1.0 1.0 25 Q9NZ08,O15460,Q6UN15 3 +Respiratory failure 0.3050079637442872 0.3538991106314389 0.7234144935767386 1.0 1.0 65 Q15165,O60934,Q5SRE5,Q70HW3,P23786,Q9Y619,P07602,Q92804,Q8TD16,P35637 10 +Anterior open bite malocclusion 0.7012236573759163 0.3534595095444954 0.7237439788992495 1.0 1.0 2 P21281 1 +Abnormal sharpey fiber morphology 0.3981745610396948 0.3501012734938735 0.7262626951939315 1.0 1.0 7 P01889 1 +Vertical nystagmus 0.6991842284160232 0.3484928385397715 0.727470091181369 1.0 1.0 2 Q9NW15 1 +Epispadias 0.3953123564634505 0.3479253015864214 0.7278962830840428 1.0 1.0 6 Q9Y619 1 +Aplasia hypoplasia affecting the fundus 0.3973550043842043 0.3478029794756883 0.727988151908086 1.0 1.0 22 Q8WWQ0,Q13509,P61978,Q8WXI9 4 +Small hand 0.370143901951757 0.3473269524321662 0.7283457045505761 1.0 1.0 30 Q10471,O60885,Q93009,Q13620,Q9UQE7,Q13509,Q69YQ0,Q9Y619,Q14320,Q96GM5,O60216,O75175,Q06787,Q08J23 14 +Abnormality of fundus pigmentation 0.5014678205883882 0.3466695546182037 0.7288395852917864 1.0 1.0 3 Q9Y619 1 +Aplasia hypoplasia of the optic nerve 0.3990156673618243 0.3459874750741977 0.7293521275664094 1.0 1.0 21 Q8WWQ0,Q13509,P61978,Q8WXI9 4 +Persistence of primary teeth 0.3940595150444307 0.3433627923596021 0.7313255472909992 1.0 1.0 6 P61586,Q9ULC3 2 +Abnormal circulating carboxylic acid concentration 0.3292148874012433 0.3432855485109326 0.7313836516210055 1.0 1.0 85 Q4G176,P00846,Q6PGP7,Q01082,O96000,P48735,O75845,P03886,P20674,O00330,Q9Y5L0,P61457,P55263,Q02241,P40855,P16930,Q9P0J0,Q4G0N4,P11182,Q8IUX1,P23786,Q9Y619 22 +Uveitis 0.3982024638099357 0.3427721967508497 0.7317698439613081 1.0 1.0 8 P01889 1 +Abnormality of head blood vessel 0.3883057910545994 0.3421954001293353 0.732203846675372 1.0 1.0 25 Q15056,P03886,P00846 3 +Long fingers 0.3061324406421506 0.3409631463456116 0.7331313260045917 1.0 1.0 67 Q96T58,Q5H8A4,Q8WWQ0,Q8WXI9,Q03164,P23786,O75175,Q03252,Q9Y263,Q15334 10 +Cervical spinal canal stenosis 0.6954452753229134 0.3394813651868332 0.7342471329094051 1.0 1.0 2 Q8IWS0 1 +Disproportionate short stature 0.3974214400267113 0.3386211764173786 0.734895127664597 1.0 1.0 21 Q15392,Q03164 2 +Hemorrhage of the eye 0.3997570639542129 0.3365577423231421 0.7364503162258016 1.0 1.0 10 P22413 1 +Abnormality of skeletal muscle fiber size 0.4008244469831112 0.3348403637138075 0.7377455104644419 1.0 1.0 18 Q9BUK6,Q8N9N2,O95831 3 +Bowing of the legs 0.2802356285576671 0.3345508730747418 0.7379639088883758 1.0 1.0 48 P35250,Q9Y5S9,P22413,O75312,Q13509,Q32P28,Q9Y619,O75431,Q15056,Q8N0X7,Q96HY6 11 +Abnormal nasal mucosa morphology 0.4315808905051622 0.3339366333512509 0.7384273755575244 1.0 1.0 4 Q13432 1 +Mild postnatal growth retardation 0.6930659415363739 0.3338108144724364 0.7385223223084694 1.0 1.0 2 P10644 1 +Abnormality of the pancreas 0.3091165882889093 0.3332379629601851 0.7389546638660842 1.0 1.0 70 Q9Y5S9,Q96MF7,Q01844,Q6PGP7,Q15904,P01889,P53985,P09601,P03886,O00330,Q9NZ08,Q92878,O60934,P10644,P25054,P16930,Q9UGP8,Q4G0N4,P00403,Q13043,O60885,P11182,P42771,Q96T58,P22413,O75489 26 +Hypopituitarism 0.3676062657001198 0.3330040499529216 0.7391312260489644 1.0 1.0 30 Q03164,Q4J6C6 2 +Short palpebral fissure 0.3885310452853353 0.3290351754537354 0.7421291008080422 1.0 1.0 24 Q9Y619,Q03164,Q13724 3 +Abnormality of the periorbital region 0.2995527112108227 0.3289713122802486 0.7421773717594911 1.0 1.0 63 Q96T58,P35250,P28070,P98175,Q6PGP7,Q9UPP1,P38159,Q8N1F7,Q8NFH4,Q8WXI9,Q01082,Q9ULC3,Q12965,P40855,O75179,Q15056,Q08J23 17 +Abnormal prostate morphology 0.394418130925367 0.3287623709427784 0.7423353070628222 1.0 1.0 8 Q92878,O60934,Q8IWS0,P25054,P42771 5 +Extra axial cerebrospinal fluid accumulation 0.6903467029231716 0.327391793242099 0.7433715728081716 1.0 1.0 2 Q03252 1 +Abnormal aortic valve cusp morphology 0.3927766242741954 0.3263145233120813 0.7441864010850165 1.0 1.0 22 Q15477,P35250,Q01082,Q9UQE7,Q15056,P61978 6 +Abnormality of temperature regulation 0.3499241263188621 0.3241510746617529 0.7458236606252051 1.0 1.0 104 Q9NZ08,P28070,P00846,O43772,Q03001,P23786,Q6UN15,P00403,P07602,O15460,Q9HC07,P35610,P03886 13 +Aplasia hypoplasia of the femur 0.3976553041223998 0.3239086548097135 0.7460071913548056 1.0 1.0 11 Q96HY6,O95831 2 +Synostosis involving digits 0.4268636602104177 0.3201788519590134 0.748832753729572 1.0 1.0 4 Q15233 1 +Abnormality of the testis size 0.3865963526170994 0.3196639421215928 0.749223096635844 1.0 1.0 24 P38159,Q9UPP1,Q8WWQ0,O75312,Q8IWS0,Q13620,Q9NP72,P21359,O15294,P18074,Q06787,O43505 12 +Erythema 0.3971127234671832 0.3188524423776431 0.7498384088458152 1.0 1.0 18 P01889,P00403,P03886 3 +Plagiocephaly 0.3691798300372899 0.3177716375855187 0.7506581663309826 1.0 1.0 29 Q01082,Q13509,Q9Y2W2,Q01105,P21281,O75175,O60701 7 +Finger clinodactyly 0.3098017278361022 0.317037649686217 0.7512150343798656 1.0 1.0 72 Q96T58,P35250,Q9Y5S9,Q8WVM7,Q9ULC3,Q9Y2U8,Q9UQE7,Q03164,Q9Y619,Q6PJG6,Q9NP72,P21281,O60885,O75175,Q03252,Q5JRA6,Q15056,Q08J23 18 +Paraplegia paraparesis 0.3082289892960734 0.3145190287128635 0.7531268663873745 1.0 1.0 71 O00330,Q8WWQ0,P00846,Q9H2M9,Q12768,O75298,O95831,Q9Y619,P35637,Q8N0X7 10 +Abnormal diaphysis morphology 0.2965598027126268 0.3143471466850892 0.7532573937551303 1.0 1.0 62 P35250,Q9Y5S9,P22413,O75312,Q96AY3,Q13509,Q32P28,Q9Y619,O75431,Q9HC07,Q15056,Q8N0X7,Q96HY6 13 +B lymphocytopenia 0.3883365403312971 0.3143185795048551 0.7532790883812917 1.0 1.0 7 Q13432,O60934 2 +Bilateral single transverse palmar creases 0.3943344321066229 0.3113064765250858 0.7555676441882919 1.0 1.0 11 O60885,P40855,Q5SRE5,Q9UQE7 4 +Genital neoplasm 0.3376937546059419 0.3103622843712298 0.7562854717001519 1.0 1.0 35 O95999,Q01844,O60934,O75874,Q9UPY3,P48735 6 +Microcornea 0.3869782911149859 0.3096041276384011 0.7568620170308635 1.0 1.0 23 Q9H2M9,Q9ULC3,Q9UQE7,Q9NP72,Q15042,P18074,O75845,Q9NWM8 8 +Increased intracranial pressure 0.3955947230395876 0.3093518892582407 0.7570538634054711 1.0 1.0 17 P07602,Q9NZ08 2 +Freckling 0.3937751384277674 0.3092007371297789 0.7571688332106763 1.0 1.0 11 O60934,P21359,P10644,P18074,P42771 5 +Disinhibition 0.2759841387685202 0.3089855331511529 0.75733253160549 1.0 1.0 47 Q96T58,Q8WWQ0,Q01082,Q8NC96,P35637,O60524,Q06787,Q9GZZ9,Q08J23 9 +Single transverse palmar crease 0.3312590832485118 0.3080097502210066 0.7580749131842228 1.0 1.0 36 P98175,A2RRP1,Q01082,Q5SRE5,Q9UID3,Q9UQE7,P40855,O60885,Q9Y263,Q8WVM7 10 +Pes valgus 0.3919458584391677 0.3072324051823854 0.758666481739714 1.0 1.0 10 Q96AA3 1 +Cerebral calcification 0.3710116119605711 0.3063647298455509 0.759326959562642 1.0 1.0 28 P23786,P00403,P18074,O75845,P03886 5 +Aplasia hypoplasia involving bones of the thorax 0.3479546616420985 0.3044929149649139 0.7607523896969717 1.0 1.0 33 Q96T58,Q12768,Q03164,Q9Y619,P21281,Q96HY6 6 +Tongue thrusting 0.4852091125467629 0.3034901843669072 0.7615163267037275 1.0 1.0 3 Q14683,P51608 2 +Decreased adipose tissue 0.3928996788030487 0.3020126672288505 0.7626424065306061 1.0 1.0 12 Q03252,O75431,P36543,P18074 4 +Opisthotonus 0.3828219734925618 0.3015935136245372 0.7629619532654794 1.0 1.0 24 Q99720,P35637 2 +Skin pit 0.3940838693609353 0.3010815809720792 0.7633522860062916 1.0 1.0 15 Q9ULC3,Q9H488,Q69YQ0,Q9Y2W2,O96028,P61978 6 +Lateral clavicle hook 0.4839834027168105 0.3003523179492727 0.7639084302833772 1.0 1.0 3 Q9Y619 1 +Schwannoma 0.4835434778009094 0.2992302118054556 0.764764399045218 1.0 1.0 3 P10644 1 +Elevated circulating parathyroid hormone level 0.4835434778009094 0.2992302118054556 0.764764399045218 1.0 1.0 3 P10644 1 +Spastic dysarthria 0.3856994899115193 0.2972824064869226 0.766250912405914 1.0 1.0 8 Q9H2M9 1 +Crumpled long bones 0.6764106050305958 0.2955475977418398 0.7675755975183147 1.0 1.0 2 O75718 1 +Elevated tissue non specific alkaline phosphatase 0.4814071920654221 0.293812342151069 0.7689013034650669 1.0 1.0 3 P22413 1 +Nonprogressive 0.3799560346901684 0.293539630019707 0.7691097124925699 1.0 1.0 6 Q9BUF5 1 +Tinnitus 0.3913751927260868 0.2932581054087708 0.7693248735965026 1.0 1.0 13 P21912,O95831,Q9NR28,P21359,O95140,Q15043 6 +Infantile spasms 0.3603505224405 0.2928773389381013 0.7696159106370779 1.0 1.0 30 P00846 1 +Progressive inability to walk 0.3865882909785955 0.2897744616244886 0.7719887866733579 1.0 1.0 21 P00846 1 +Volvulus 0.3786012835552675 0.2889087395427105 0.7726512156010492 1.0 1.0 6 Q9UQE7,Q9UID3,O60885 3 +Abnormal blood inorganic cation concentration 0.3342438458492373 0.2886247096444252 0.7728685843123198 1.0 1.0 35 Q96DF8,Q4J6C6,P61457 3 +Peripheral cyanosis 0.381001021450458 0.2885608189969339 0.7729174824222707 1.0 1.0 7 P04066,P55265,Q9UHD8,O75792,O95163,Q03426 6 +Small nail 0.2778611136419747 0.2876006422316028 0.7736524532119708 1.0 1.0 43 Q96T58,Q12768,P23786,Q9UQ13,O75431,P21281,P18074,Q15056,Q08J23 9 +Progeroid facial appearance 0.3777452724347979 0.2859972309498816 0.7748802424009256 1.0 1.0 6 O75431 1 +Pulmonic stenosis 0.3590699620843219 0.2859281560364356 0.7749331481988209 1.0 1.0 30 P35250,P22413,O95235,Q12768,P55263,Q9ULC3,Q9UQE7,Q9UQ13,Q15056 9 +Woolly hair 0.3774710471248259 0.2850669199123349 0.7755928730841601 1.0 1.0 6 Q15477 1 +Abnormality of the calf 0.2837038158045833 0.2831044170783774 0.7770967957136359 1.0 1.0 55 P35250,Q9Y5S9,P22413,O75312,O95831,Q13509,Q32P28,Q9Y619,O75431,Q15056,Q8N0X7,Q96HY6 12 +Hypoglycemic coma 0.3828194404683074 0.280231763727937 0.7792996986106671 1.0 1.0 9 P31751 1 +Abnormality of the lymph nodes 0.3268673374831457 0.2795866896706619 0.7797946201142953 1.0 1.0 36 P28070,Q9NZ08,Q01844,O95999,P01889,Q6UN15,O15460,P33991 8 +First degree atrioventricular block 0.6689326988443284 0.2792051353614289 0.7800874028452853 1.0 1.0 2 P02545 1 +Mandibular aplasia 0.4012624017166113 0.2775061404235434 0.7813914915275257 1.0 1.0 5 Q9Y619 1 +Abnormality of chromosome stability 0.3849881378728915 0.2767704375283656 0.7819563821778277 1.0 1.0 11 Q06787,O60934,P33991 3 +Single fiber emg abnormality 0.4743965800071902 0.2763997683893742 0.7822410345925646 1.0 1.0 3 Q06210 1 +Muscle fiber tubular inclusions 0.4743965800071902 0.2763997683893742 0.7822410345925646 1.0 1.0 3 Q06210 1 +Reduced forced vital capacity 0.4007255121148254 0.2759285023072432 0.7826029817360518 1.0 1.0 5 Q9BQT8,P06753,O95817 3 +Abscess 0.3828679837221821 0.2743387881322708 0.7838242788774439 1.0 1.0 10 O14920 1 +Epidermoid cyst 0.4098741964151654 0.2730118546001178 0.7848441029698636 1.0 1.0 4 P25054,O60716 2 +Abnormal prolactin level 0.4098639455782196 0.2729845623814861 0.7848650824802632 1.0 1.0 4 Q9UMX1,Q969G3,P10644 3 +Abnormal morphology of the conjunctival vasculature 0.3738067853794274 0.2727487594983731 0.7850463505081253 1.0 1.0 6 Q9NW15 1 +Abnormality of the fontanelles or cranial sutures 0.3317329063400003 0.2718679868785202 0.785723527173229 1.0 1.0 94 Q12768,Q01082,Q9Y2U8,O75845,P36543,P61978,Q08J23,O00330,P20674,P98175,O95831,P40855,P21281,P18074,Q5SRE5,Q9ULC3,Q96AY3,Q9UQE7,O75431,Q32P28,Q96T58,P22413,Q69YQ0,Q9Y619,Q00577 25 +Ketonuria 0.3832922408558019 0.2706566142562995 0.78665514844099 1.0 1.0 11 O00330 1 +Abnormal pelvis bone morphology 0.664853840924546 0.2705154655810949 0.7867637204915461 1.0 1.0 2 P16435 1 +Avascular necrosis of the capital femoral epiphysis 0.6648538409245459 0.2705154655810944 0.7867637204915465 1.0 1.0 2 Q9H3U1 1 +Loss of eyelashes 0.4719483168990294 0.2704535122771263 0.7868113764971212 1.0 1.0 3 P02545,P06132 2 +Peripheral axonal degeneration 0.3028130536007574 0.2687453886362926 0.7881256211403198 1.0 1.0 71 O00330,Q8N9N2,P00846,O95831,Q13509,P07602,P00403,O60524,Q9BQT8,P03886 10 +Persistent head lag 0.3751382570676966 0.2685738706664123 0.7882576219015778 1.0 1.0 7 Q01082 1 +Emotional lability 0.2765597887292437 0.2676071778305993 0.7890017053162857 1.0 1.0 51 Q15165,Q13509,Q7KZN9,P07602,Q92804,P50995,P35637,Q8N0X7 8 +Progressive hearing impairment 0.3849338439742159 0.2653704956041501 0.7907240626970069 1.0 1.0 15 P03886 1 +Aplasia hypoplasia of the vagina 0.469568174090453 0.2647404882643975 0.7912093848458204 1.0 1.0 3 Q8IY37,P51809 2 +Increased bone mineral density 0.3746403362469229 0.2634299374444767 0.7922192184844101 1.0 1.0 24 Q15392,P22413,Q9Y2U8,P18074,Q15056,P54802 6 +Urticaria 0.3775889615087314 0.2620339704776485 0.7932952522837551 1.0 1.0 9 Q9Y5L0,Q03426,P18074 3 +Prominent occiput 0.3808752895535616 0.2620271067782592 0.7933005439078538 1.0 1.0 11 O75175,Q12768,Q13724 3 +Oligodontia 0.3754959116780566 0.2619345599190897 0.7933718945804336 1.0 1.0 8 P61978,P21281 2 +Renovascular hypertension 0.3754726525182716 0.2618559074005169 0.7934325345198303 1.0 1.0 8 P42224,P35250,P78347,P21359,Q15056 5 +Abnormality of the hairline 0.3181949241708547 0.2609396572624819 0.7941390418789069 1.0 1.0 84 Q8TAQ2,Q9H2M9,Q12768,Q9UID3,Q9UQ13,Q15042,O75175,Q08J23,Q9UPP1,O60934,O95831,Q9Y2W2,Q9NP72,P40855,P21281,P25054,O75179,Q5H8A4,Q92643,Q9UQE7,O60885,Q96T58,P62899,Q69YQ0 24 +Abnormality of the intrahepatic bile duct 0.4671532566316059 0.2590128774474527 0.795625304696564 1.0 1.0 3 Q9Y5L0 1 +Abnormality of skull ossification 0.3812536723339489 0.2589883897605041 0.7956441985830034 1.0 1.0 12 Q32P28 1 +Hypoplastic aortic arch 0.4668480108806675 0.2582938749574521 0.7961801130048474 1.0 1.0 3 P30153,Q9UHX1 2 +Lacrimal duct stenosis 0.4668480108806652 0.2582938749574472 0.7961801130048511 1.0 1.0 3 P48651,Q13428 2 +Type 1 muscle fiber atrophy 0.3718251101558565 0.2575233843791476 0.7967747657539923 1.0 1.0 7 P61978 1 +Abnormal labia morphology 0.3817505706408552 0.2552684544683128 0.7985157626997366 1.0 1.0 18 O60885,Q9H2M9,Q9UQE7,Q9Y619,Q9NP72,Q15042,O60216,P02545 8 +Abnormal distal phalanx morphology of finger 0.2817445389201858 0.2544352016356045 0.7991593585773809 1.0 1.0 42 P82673,Q8WXI9,Q9H2M9,Q9Y2U8,Q15042,O75431,P21281 7 +Generalized osteoporosis 0.4650418400391277 0.2540623944794067 0.7994473551832006 1.0 1.0 3 P42224 1 +Abnormality of the elbow 0.2759634980532214 0.2513557043592977 0.801539111299701 1.0 1.0 52 P22413,Q96AY3,Q9UQE7,Q03164,Q13509,P23786,Q9Y619,Q9UQ13,P50402,Q8WVM7 10 +Prostate neoplasm 0.3698473640252356 0.2510131080070565 0.8018039748472254 1.0 1.0 7 Q92878,O60934,P25054,P42771 4 +Abnormal thoracic spine morphology 0.3735717014824897 0.2486623357184776 0.8036219855728932 1.0 1.0 23 Q13724,Q13509,O95831,P18074,O75845 5 +Aplasia hypoplasia involving bones of the lower limbs 0.3116387868115769 0.2479309334639169 0.8041878455205622 1.0 1.0 80 Q9Y5S9,Q9H2M9,Q03164,O75175,Q8N0X7,Q08J23,O95831,P21281,Q06787,Q96HY6,Q5H8A4,Q9ULC3,Q96AY3,Q9UQE7,O75431,O60885,Q5JRA6,Q96T58,Q13509,Q9Y619,Q14320 21 +Dysmetria 0.2795137467153194 0.2477902518424657 0.8042966976709758 1.0 1.0 55 P35250,Q5JRX3,Q12768,Q15056,Q96D71,Q9NPL8,Q6PJG6,Q9BUK6,Q06787,Q8N0X7,Q9NW15 11 +Cutaneous cyst 0.3906891196259845 0.2471977207018739 0.8047552091954697 1.0 1.0 5 P25054,O60716,Q9H488 3 +Coarse facial features 0.2820021854126945 0.2465598596079476 0.8052488729375864 1.0 1.0 57 Q96T58,P35250,P38159,O95831,P21281,P18074,Q15056,Q06787,P54802,Q9Y263,P61978 11 +Pes cavus 0.3284827111107199 0.2453986393679315 0.8061477824369048 1.0 1.0 94 Q99720,Q96T58,Q8WWQ0,O75298,Q12768,O95831,Q96D71,P21281,Q9BUK6,O75175,Q8N0X7,Q08J23,Q9NW15 13 +Abnormality of t cell physiology 0.3768360387617737 0.2432764688137731 0.8077912320608323 1.0 1.0 12 Q96DF8 1 +Typical absence seizure 0.3766623284261636 0.2426657410780989 0.8082643489160648 1.0 1.0 12 P49419,P61978 2 +Lethargy 0.3034475426056675 0.2425768860846303 0.8083331887012108 1.0 1.0 74 P62899,Q16836,A2RRP1,O43772,O43676,Q9NWS8,P23786,P11310,Q9NPL8,P03886,O96000,Q9Y619,P11182,P20674 14 +Abnormally folded helix 0.3778827138865532 0.2406250502137088 0.8098457332827944 1.0 1.0 14 P23786 1 +Proportionate tall stature 0.6492182188987137 0.2387039639422585 0.8113351428188242 1.0 1.0 2 P21359 1 +Elevated circulating growth hormone concentration 0.6492182188987137 0.2387039639422585 0.8113351428188242 1.0 1.0 2 P10644 1 +Pituitary prolactin cell adenoma 0.6492182188987137 0.2387039639422585 0.8113351428188242 1.0 1.0 2 P10644 1 +Dysmenorrhea 0.6492182188987136 0.2387039639422582 0.8113351428188245 1.0 1.0 2 P02545 1 +Increased circulating acth level 0.6492182188987136 0.2387039639422582 0.8113351428188245 1.0 1.0 2 P16435 1 +Anorexia 0.3712261105116996 0.2383937039146879 0.8115757502321725 1.0 1.0 23 Q9NZ08,O15460,P35610,Q6UN15 4 +Fetal onset 0.3874626957467237 0.2382754663706389 0.8116674484226185 1.0 1.0 5 O95235 1 +Abnormal size of the palpebral fissures 0.3053174129886467 0.2372710603321514 0.8124465116322643 1.0 1.0 76 Q96T58,Q96DF8,P38159,Q13724,Q8WXI9,Q03164,Q9Y619,Q15056,O75175,O60701,P61978 11 +Decreased circulating antibody level 0.3011104339352941 0.2366776095943245 0.8129069064512868 1.0 1.0 39 Q15477,Q9Y5S9,O95999,Q6PGP7,Q13724,O60934,O14920,Q9Y4L1,P17812,P18074 10 +Aplasia hypoplasia of the sacrum 0.455967358041487 0.2334034936347597 0.8154481005586223 1.0 1.0 3 Q8TAA9,P39019 2 +Recurrent viral infections 0.373788333523496 0.2326406216145346 0.8160404811206599 1.0 1.0 12 P42224,P33991,Q13432,P17812 4 +Abnormal metabolism 0.2641494409828098 0.2310214627371759 0.8172981281408627 1.0 1.0 45 Q8TCJ2,Q10471,Q4G176,P22413,Q8N511,Q9UDY2,Q99707,Q01082,Q13043,P18074,Q96AA3,P36543,P46783 13 +Dilatation of the cerebral artery 0.3657262476815907 0.2297015163305312 0.8183237165498496 1.0 1.0 8 P42224,Q01082,P10644 3 +Brain imaging abnormality 0.3392946152317624 0.2271109680370296 0.8203374556166603 1.0 1.0 32 P07602,P00403,P03886 3 +Abnormality of the distal phalanges of the toes 0.3917551463712634 0.2270810109514822 0.820360749439911 1.0 1.0 4 O75431 1 +Aortic regurgitation 0.3663998935895342 0.2264767887180584 0.820830610185403 1.0 1.0 24 Q15477,Q9NZ08,Q6PGP7,P01889,Q01082,Q9UQ13 6 +Medulloblastoma 0.364169304121387 0.2247169890352848 0.8221994472654934 1.0 1.0 8 P25054,O60934,Q9UPY3 3 +Fragile nails 0.3610501970093003 0.2228582583104359 0.8236458244103639 1.0 1.0 7 Q10567,Q13555,P18074 3 +Myopathy 0.3290925305626828 0.2215326799195668 0.8246776937499427 1.0 1.0 97 P35250,P00846,Q9BUK6,Q03252,P50402,P03886,O14979,O43676,P51114,Q7Z406,Q9NWM8,Q07021,P11310,P00403,Q86U42,Q96T58,P09493,Q9NWS8,P23786,P51530,Q15056 21 +Thickened cortex of long bones 0.4505270316219075 0.2215061353377307 0.8246983599367321 1.0 1.0 3 P21359,O00754 2 +Thin clavicles 0.4505270316218986 0.2215061353377114 0.8246983599367472 1.0 1.0 3 O75844,P02545 2 +Abnormality of metacarpal epiphyses 0.3807417488941828 0.220195170203338 0.8257191579461509 1.0 1.0 5 P16435,Q13363,O95202,O96028 4 +Abnormal large intestine physiology 0.3721702311998003 0.2178991450467463 0.8275076932961876 1.0 1.0 18 P07602,O75298 2 +Abnormality of metacarpophalangeal joint 0.3875460951499953 0.217091162879097 0.8281373007518764 1.0 1.0 4 P16435,Q15233 2 +Focal tonic seizure 0.6376614547926445 0.2167502199758417 0.8284030083299927 1.0 1.0 2 Q00577 1 +Abnormal blistering of the skin 0.3717669816636744 0.2163672263977526 0.828701510744883 1.0 1.0 18 Q96T58,Q9NZ08 2 +Prematurely aged appearance 0.3166568191556566 0.2159985064194672 0.8289889117915861 1.0 1.0 36 P35250,P22413,Q9H2M9,Q13126,Q15042,O75431,P18074,Q15056,Q03252 9 +Neoplasm of head and neck 0.367431185452187 0.2158952208439967 0.8290694224720412 1.0 1.0 11 P42224,Q8N9N2,O60216,Q9UNW1,P25054,P42771 6 +Delayed gross motor development 0.3342501098403714 0.215459121040231 0.8294093802555125 1.0 1.0 102 Q99720,Q9H2M9,Q13509,Q03164,Q9UID3,P48449,Q6PJG6,Q96D71,Q01105,Q9UQ13,Q15042,P35637,O75175,P61978 14 +Abnormal circulating sulfur amino acid concentration 0.3582504592791244 0.2141802550392857 0.8304064930133022 1.0 1.0 7 P16930,P55263,Q6PGP7 3 +Hyperpituitarism 0.3708078573531149 0.2127372283765857 0.8315319273117547 1.0 1.0 18 Q9BUK6,Q06787 2 +Hyperhidrosis 0.340987489950996 0.21273248149611 0.8315356300338421 1.0 1.0 31 P01889,Q03001,O15460,Q9Y263,P61978 5 +Muscle fiber inclusion bodies 0.3603156223090241 0.2125648519616725 0.8316663889523264 1.0 1.0 8 O43676,O75340,P09651,Q06210 4 +Skin rash 0.3706263592011308 0.2113779775536085 0.8325923398748363 1.0 1.0 16 P28070,P18074 2 +Heart block 0.3665451722683208 0.211130932946575 0.8327851032378186 1.0 1.0 22 O43772 1 +Abnormality of tibia morphology 0.369246696986542 0.2099610268675227 0.8336980910563689 1.0 1.0 14 Q9Y5S9,Q32P28,O95831 3 +Abnormal tongue physiology 0.369298475074267 0.2089760279824451 0.8344669523539501 1.0 1.0 19 P51114,Q9BQT8,O95831,P04350 4 +Insidious onset 0.3831997138366179 0.2070520879366545 0.8359691794927904 1.0 1.0 4 Q12768 1 +Hyperintensity of cerebral white matter on mri 0.3679967596755905 0.2070164790432616 0.8359969888476853 1.0 1.0 20 Q9BUK6,Q96AA3 2 +Oromotor apraxia 0.3529647003231621 0.2068920807947753 0.8360941413283878 1.0 1.0 6 Q9H270,P42356 2 +Short upper lip 0.3823129251700746 0.2050386522636849 0.837541926365863 1.0 1.0 4 Q8N766,O96028,Q13363 3 +Childhood onset sensorineural hearing impairment 0.4424703225735666 0.2045720708411368 0.8379064781334367 1.0 1.0 3 P23634 1 +Prelingual sensorineural hearing impairment 0.4424703225735666 0.2045720708411368 0.8379064781334367 1.0 1.0 3 P23634 1 +Subcortical heterotopia 0.3812925170067988 0.2027365184237816 0.8393409782791441 1.0 1.0 4 P43034,O00139,Q9BSJ2 3 +Subcortical band heterotopia 0.3812925170067988 0.2027365184237816 0.8393409782791441 1.0 1.0 4 P43034,O00139,Q9BSJ2 3 +Infantile axial hypotonia 0.3615001909630509 0.2024279374486552 0.8395821895406042 1.0 1.0 10 P07602 1 +Dysphagia 0.3610100337209108 0.2021395877888304 0.8398076000270078 1.0 1.0 127 Q99720,Q96T58,P82673,Q8N9N2,P00846,P01889,P04350,O75874,Q03164,Q96D71,P07602,Q01105,P48735,P35637,Q9Y263,Q06787,P03886 17 +Pseudoepiphyses of the metacarpals 0.380612244897965 0.2012105087026417 0.8405339747768119 1.0 1.0 4 O96028,Q13363,O95202 3 +Fine hair 0.3643490405818703 0.2007931158909466 0.8408603460306914 1.0 1.0 12 A2RRP1,Q08J23,Q8WXI9 3 +Abnormal iris pigmentation 0.3676550155559682 0.2003071171906549 0.841240396634924 1.0 1.0 17 Q96T58,Q96EV8,P35250,P78347,P40855,P10644,Q15056 7 +External ophthalmoplegia 0.3670175481649645 0.2002871319793538 0.8412560258471753 1.0 1.0 19 Q13509,P00403,P03886,P51530 4 +Abnormal cerebral artery morphology 0.3606694945488395 0.1997991698399777 0.8416376506087593 1.0 1.0 10 P42224,Q01082,P10644 3 +Flat cornea 0.3504810431982289 0.1995466366851657 0.8418351660089474 1.0 1.0 6 Q15056 1 +Phonophobia 0.3504810431982289 0.1995466366851657 0.8418351660089474 1.0 1.0 6 Q15056 1 +Nystagmus induced head nodding 0.3504810431982289 0.1995466366851657 0.8418351660089474 1.0 1.0 6 Q15056 1 +Overfriendliness 0.3504810431982289 0.1995466366851657 0.8418351660089474 1.0 1.0 6 Q15056 1 +Postnatal growth retardation 0.2774793710125921 0.1991125646797217 0.8421746928235341 1.0 1.0 58 A2RRP1,O60885,Q9H2M9,Q12768,Q8TAQ2,O95235,Q9UQE7,Q03164,Q13509,Q9NP72,O75431,P33991,O75179,Q08J23 14 +St segment elevation 0.6274643099932076 0.1985000388809742 0.8426538543331776 1.0 1.0 2 Q9HD47 1 +Abnormal st segment 0.6274643099932076 0.1985000388809742 0.8426538543331776 1.0 1.0 2 Q9HD47 1 +Unusual fungal infection 0.3619755226784931 0.1981193601754351 0.8429516778244635 1.0 1.0 11 P42224,Q9Y5L0,O14920,Q13043 4 +Low anterior hairline 0.2640648244183934 0.1974711838207086 0.8434588294167047 1.0 1.0 48 Q96T58,P62899,Q9H2M9,O60934,Q8TAQ2,O95831,Q9UQE7,Q9NP72,P21281,O60885,Q08J23 11 +Thick cerebral cortex 0.3718952024498149 0.1974651402927816 0.8434635583504115 1.0 1.0 5 P43034,P38606,Q9Y487,P36543 4 +Limitation of neck motion 0.4376062563753835 0.1947495674103305 0.8455890055824022 1.0 1.0 3 O94905,P02545 2 +Tics 0.3517082507674977 0.1944510860972985 0.8458226922821233 1.0 1.0 7 Q8WXI9 1 +Abnormal conjunctiva morphology 0.361533484190883 0.1908292637551318 0.8486593608132325 1.0 1.0 22 P01889,Q9NZ08,P28070,Q9NW15 4 +Bone fracture 0.346094749918704 0.1868478490224535 0.8517799294070951 1.0 1.0 6 Q13724 1 +Basal cell carcinoma 0.3582557492853122 0.186325717663875 0.8521893408091736 1.0 1.0 11 P25054,P02545,Q9UPY3,P18074 4 +Delayed epiphyseal ossification 0.4330727036962933 0.1858691975684774 0.8525473380312327 1.0 1.0 3 Q96HY6 1 +Scarring 0.3432254231300595 0.1857264213906824 0.8526593075239073 1.0 1.0 29 P04439,O43172,Q9Y2U8,Q03001,Q92620,O43837,Q9NWM8 7 +Truncal ataxia 0.3631701473299935 0.1845305196689408 0.8535972870046102 1.0 1.0 18 Q9BUK6,Q5THJ4,Q9NW15 3 +Primary peritoneal carcinoma 0.3660470984409245 0.1831232819943471 0.8547012882652236 1.0 1.0 5 O60934 1 +Lipid accumulation in hepatocytes 0.2896112046633283 0.1828805425903898 0.8548917501798252 1.0 1.0 69 Q96T58,Q16836,Q8N511,O43772,O75312,Q01082,P55263,Q9NWS8,Q7KZN9,P23786,P11310,O75431,P31751 13 +Abnormality of the nasal dorsum 0.2620969159536014 0.1817829402307178 0.8557530731750207 1.0 1.0 48 Q96T58,O75312,O60934,Q5SRE5,P51530,P18074,O75175,P61978 8 +Narrow nasal bridge 0.4308058483509049 0.1815288111936929 0.8559525207408709 1.0 1.0 3 Q9UMX1,Q15233 2 +Decreased light and dark adapted electroretinogram amplitude 0.4304907022538335 0.1809306873480105 0.8564219813306253 1.0 1.0 3 O43837 1 +Abnormality of humoral immunity 0.2672955459689885 0.1809127570308981 0.8564360554173582 1.0 1.0 52 Q15477,Q9Y5L0,Q9Y5S9,P28070,Q6PGP7,O95999,Q13724,O60934,O14920,Q9Y4L1,P17812,Q03252,P18074 13 +Supravalvular aortic stenosis 0.3468412192339253 0.1802839597727994 0.8569296475967594 1.0 1.0 7 Q15056 1 +Inflammatory abnormality of the eye 0.3258217149696463 0.1797992759846897 0.8573101520347559 1.0 1.0 33 Q15800,Q9NZ08,P28070,O95999,P01889,Q9UQE7,P18074,P04439 8 +Narrow vertebral interpedicular distance 0.4293324792828284 0.178743579492045 0.8581390486943772 1.0 1.0 3 Q96HY6 1 +Vertebral arch anomaly 0.4293324792828284 0.178743579492045 0.8581390486943772 1.0 1.0 3 Q96HY6 1 +Abnormal thyroid stimulating hormone level 0.6148878314072066 0.1774532435453088 0.8591523885532284 1.0 1.0 2 P10644 1 +Capillary malformation 0.3579013767024794 0.1755817316636151 0.8606225553938092 1.0 1.0 13 Q15056,P35250,Q9Y5S9 3 +Sinus bradycardia 0.6128484024473211 0.1741929394621294 0.8617138342040904 1.0 1.0 2 P02545 1 +Second degree atrioventricular block 0.6128484024473211 0.1741929394621294 0.8617138342040904 1.0 1.0 2 P02545 1 +Cerebral visual impairment 0.274269283066864 0.1738421410219098 0.8619895248542511 1.0 1.0 58 Q9BSJ2,Q9H2M9,Q9UID3,Q9NP72,Q4G0N4,Q15042,P00403,Q01105,O60524,P03886,Q08J23 11 +Epileptic spasm 0.2728402139691415 0.17288106863482 0.8627449126226279 1.0 1.0 57 P00846,Q01082,Q01105,P49419,Q6PJT7,O60524,O60701,P03886,Q08J23 9 +Chronic sinusitis 0.3670068027210941 0.1721753098217911 0.8632997079097664 1.0 1.0 4 Q03519,O95394,Q86Y56 3 +Somatic sensory dysfunction 0.3238887865506201 0.1719509691759048 0.8634760756803781 1.0 1.0 98 Q9NZ08,P00846,P01889,O75298,Q12768,O95831,Q9Y619,P07602,O15460,Q9BUK6,Q06787,P54802,P61978 13 +Poor motor coordination 0.3578824122258964 0.1718531463025998 0.8635529822971233 1.0 1.0 14 O00330 1 +Abnormal rib cage morphology 0.2878495046153863 0.1692654551659689 0.8655878466589839 1.0 1.0 69 Q96T58,Q5H8A4,Q9Y5S9,Q12768,O95831,Q03164,Q9Y619,P21281,P54802,Q32P28,Q96HY6 11 +Hoarse voice 0.3507524336854672 0.1689821480886554 0.8658106832221564 1.0 1.0 25 P35250,Q01082,Q9Y2U8,Q9UQ13,Q15056,Q7Z406,Q8N0X7,Q96HY6 8 +Menorrhagia 0.6087695445275387 0.16780023057608 0.8667404410979982 1.0 1.0 2 P35579 1 +Chorioretinal atrophy 0.3591631696026833 0.1669543704856666 0.867405951991221 1.0 1.0 5 Q9Y619 1 +Hand muscle weakness 0.3463463625287027 0.1633680233445953 0.8702286782902007 1.0 1.0 9 Q8TD16,O95140,P31483 3 +Cavum septum pellucidum 0.3485878364599696 0.1630665630728176 0.8704660261766537 1.0 1.0 10 Q9Y5S9,Q69YQ0 2 +Abnormal ovarian physiology 0.3561336725065786 0.1622664989583608 0.8710959949731332 1.0 1.0 20 Q06787,O60934,Q8WWQ0 3 +Hamartomatous polyposis 0.4199251955117317 0.1616289028325825 0.8715980953999725 1.0 1.0 3 P21912,Q9UMX1 2 +Personality changes 0.356468138150443 0.1610826986656968 0.8720282667535089 1.0 1.0 17 P03886 1 +Nevus 0.341054711417959 0.1608613928365474 0.8722025702883975 1.0 1.0 28 P35250,Q9Y5S9,Q01082,Q9Y2U8,Q96AY3,P18074,Q15056 7 +Brachydactyly 0.2799554583979448 0.1578110934800528 0.8746056568677514 1.0 1.0 64 Q96T58,A2RRP1,Q12768,O95831,Q92643,P48449,Q9UQ13,Q8N0X7,Q08J23 9 +Alopecia 0.3064664141029002 0.1563840022939468 0.8757303463500625 1.0 1.0 36 Q13724,P01889,O75312,P48449,O15460,P18074 6 +Elfin facies 0.3381450269988081 0.1560864173632212 0.8759649045135438 1.0 1.0 7 Q15056,P35250,Q9Y285,P78347 4 +Intracranial meningioma 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q969G3 1 +Transient global amnesia 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q969G3 1 +Hypothalamic hypothyroidism 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q969G3 1 +Neuralgia 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q969G3 1 +Decreased circulating follicle stimulating hormone concentration 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q969G3 1 +Decreased circulating gonadotropin concentration 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q969G3 1 +Ear pain 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q969G3 1 +Maternal diabetes 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q8TAA9 1 +Progressive pulmonary function impairment 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q969G3 1 +Brain stem compression 0.5995921142080283 0.1540392727840222 0.8775787699085105 1.0 1.0 2 Q969G3 1 +Neoplasm of the heart 0.5995921142080163 0.1540392727840047 0.8775787699085242 1.0 1.0 2 P10644 1 +Autism 0.3004805179627963 0.1538717124673766 0.8777108886249256 1.0 1.0 37 Q96T58,P35250,Q01082,Q9UQE7,Q8NC96,Q15056,Q06787,Q9GZZ9 8 +Glomerulopathy 0.3451265443300457 0.153073275332103 0.8783404906756338 1.0 1.0 10 P01889,Q9NZ08 2 +Tetraplegia 0.3503361835906122 0.1520132285638047 0.8791765020234501 1.0 1.0 13 O95831 1 +Adrenal hypoplasia 0.3393651549999007 0.151327216919013 0.8797176005071885 1.0 1.0 8 Q8WWQ0 1 +Impaired adp induced platelet aggregation 0.5975526852481372 0.1510980602084725 0.8798983626627026 1.0 1.0 2 P27797 1 +Abnormality of vitamin k metabolism 0.3513755668853207 0.1496084742770049 0.8810735219328829 1.0 1.0 5 Q9UDY2 1 +Flank pain 0.5951733514615974 0.1477201373492359 0.8825636386841731 1.0 1.0 2 P27797 1 +Joint contracture of the hand 0.2873881719286303 0.1469975998144483 0.8831339148117654 1.0 1.0 39 Q96T58,Q15392,Q13509,Q9Y619,Q15042 5 +Verrucae 0.5941536369816431 0.1462900609734191 0.8836924116444824 1.0 1.0 2 Q13043 1 +Deeply set eye 0.2756674430566365 0.1448541466853568 0.8848260301404851 1.0 1.0 62 Q96T58,Q8WXI9,Q06787,O75312,Q01082,Q9Y2U8,Q15042,P18074,O75179,O75175,O60701,Q8WVM7 12 +Abnormality of the frontal hairline 0.2795092639250667 0.1447350005207409 0.8849201036907541 1.0 1.0 65 Q96T58,Q5H8A4,P62899,O60885,Q9H2M9,O60934,O95831,Q9UQE7,Q92643,Q69YQ0,Q9NP72,P21281,O75179,Q08J23 14 +Abnormality of corneal thickness 0.3478091561928296 0.1444084163624881 0.8851779711754806 1.0 1.0 13 Q92620,O43837,Q8WWY3,O43172 4 +Abnormal response to endocrine stimulation test 0.4097245834750118 0.1443825580500513 0.8851983891523627 1.0 1.0 3 P16435,Q13423 2 +Reduced circulating prolactin concentration 0.4097245834750063 0.1443825580500423 0.8851983891523698 1.0 1.0 3 Q9UMX1,Q969G3 2 +Abnormality of earlobe 0.3477336528015428 0.1427434442559884 0.8864928044639819 1.0 1.0 23 P10586,Q15392 2 +Abnormality of extrapyramidal motor function 0.2830753106242302 0.14274112396086 0.886494637026656 1.0 1.0 68 Q99720,P61457,P07602,P35637,Q15056,P35610 6 +Caesarian section 0.3508671977245335 0.1414542746289619 0.8875110803076596 1.0 1.0 4 P33991 1 +Difficulty standing 0.3503401360544269 0.1405197087403581 0.8882493816594279 1.0 1.0 4 Q15813,Q92734,Q8WVX9 3 +Abnormal pyramidal sign 0.3381926786473698 0.1398233571566415 0.88879955823876 1.0 1.0 114 Q99720,Q9NZ08,P00846,P01889,O75298,Q12768,O95831,Q9Y619,Q6PJG6,P07602,P18074,P35637,O60701,Q8N0X7,Q9Y263 15 +Abnormal heart sound 0.3491253668933397 0.1383822822572382 0.8899382990020877 1.0 1.0 4 Q01082 1 +Abnormal brainstem morphology 0.2987596935352137 0.1380926421039042 0.8901672008151909 1.0 1.0 81 O00330,P11177,O43676,Q9Y3C6,O95831,Q13509,Q9UID3,Q9UNW1,Q9NPL8,O96000,Q06787,P03886,O00429 13 +Alopecia of scalp 0.3276387928310071 0.1373793560501164 0.8907309478106566 1.0 1.0 6 P18074 1 +Progressive spasticity 0.3476663648148211 0.1365376949163925 0.8913962273277287 1.0 1.0 15 P07602,Q4G0N4,Q9Y263 3 +Abnormality of male internal genitalia 0.3390488295370682 0.1361140558024739 0.8917311160198378 1.0 1.0 10 Q92878,O60934,Q8IWS0,P25054,P42771 5 +Focal onset seizure 0.2871007138377367 0.1349862164039448 0.8926227722983793 1.0 1.0 72 Q4G176,O00429,Q9Y3C6,Q01082,Q13509,P07602,P00403,Q01105,Q6PJG6,P49419,P21281,Q6PJT7,O60524,P03886,Q08J23,Q00577 16 +Abnormal renal insterstitial morphology 0.3407177718452246 0.1344402958773753 0.8930544193369288 1.0 1.0 11 Q15056,P23786 2 +Abnormality of the pineal gland 0.3439875842086584 0.1340934592517463 0.8933286716942921 1.0 1.0 5 Q10471,Q15233 2 +Abnormal pineal morphology 0.3439875842086584 0.1340934592517463 0.8933286716942921 1.0 1.0 5 Q10471,Q15233 2 +Pineal cyst 0.3439875842086584 0.1340934592517463 0.8933286716942921 1.0 1.0 5 Q10471,Q15233 2 +Ichthyosis 0.3318325503864677 0.1337827586778555 0.8935743612077569 1.0 1.0 29 Q15800,Q8WWQ0,P48449,Q9UQ13,P18074 5 +Skeletal dysplasia 0.3210093376156563 0.133674989695341 0.893659582969972 1.0 1.0 32 Q8WWQ0,Q9Y2U8,O95831,Q9HC07,Q96HY6 5 +Constriction of peripheral visual field 0.3482919859823594 0.1334121553064158 0.8938674327974319 1.0 1.0 19 P00846 1 +Abnormality of limb epiphysis morphology 0.3451756041813677 0.1331722671549567 0.8940571430681434 1.0 1.0 23 P82673,P16435,Q9ULC3,Q6NUQ1,O95831,P10644,O96028,Q5JRA6 8 +Aplasia hypoplasia of the spleen 0.4025841550493016 0.1331224240359757 0.8940965611638134 1.0 1.0 3 Q8TD19,Q86Y56 2 +Slowly progressive 0.2610095950444534 0.1326610728394926 0.8944614300589686 1.0 1.0 52 Q99720 1 +Abnormal labia majora morphology 0.3419254032529301 0.1322008874711692 0.8948253991827857 1.0 1.0 12 Q9Y619,Q9H2M9,Q9UQE7 3 +Hypoplastic labia majora 0.3419254032529301 0.1322008874711692 0.8948253991827857 1.0 1.0 12 Q9Y619,Q9H2M9,Q9UQE7 3 +Low set posteriorly rotated ears 0.2775959042328975 0.1304936098308254 0.896175909531159 1.0 1.0 65 P82673,Q96T58,P35250,Q9Y5S9,Q15392,Q5H8A4,Q9H2M9,Q9UQE7,Q9NP72,Q9UQ13,Q15042,Q15056,Q9Y263,Q08J23,Q4J6C6 15 +Abnormal circulating bilirubin concentration 0.3410901343053434 0.1301107016392587 0.8964788434121658 1.0 1.0 25 Q9Y5L0,Q01082,P55263,Q9UGP8,P23786,Q02241,P40855,O75845 8 +Hip pain 0.3419161843548448 0.1299091514662173 0.8966383038261614 1.0 1.0 5 P22626,P02545 2 +Cranial asymmetry 0.3243966618536257 0.1293704652862461 0.8970645165487605 1.0 1.0 6 P40855,Q69YQ0 2 +Genu valgum 0.3200664156204074 0.1291683275799351 0.8972244571552384 1.0 1.0 32 P35250,P22413,O75312,Q01082,Q13509,Q9Y619,O75431,Q15056,Q8N0X7 9 +Diabetes insipidus 0.342361104450624 0.1284790700420382 0.897769860629998 1.0 1.0 13 Q8WWQ0,O15460 2 +Gastrointestinal stroma tumor 0.3986423881845039 0.1271919646710032 0.8987884649925468 1.0 1.0 3 P21359 1 +Abnormal leukocyte physiology 0.2681108942155817 0.1271287141130067 0.8988385252646176 1.0 1.0 58 Q15477,Q9Y5L0,Q9Y5S9,P28070,Q6PGP7,Q96DF8,Q13724,O95999,O60934,O14920,Q9Y4L1,P17812,P18074 13 +Thin skin 0.3456909254914868 0.1256424265236034 0.9000149775368014 1.0 1.0 20 P46821,Q6ZXV5,Q9Y619,Q13126,O75431,P10644,P18074,Q06787 8 +Abnormal mitochondrial morphology 0.3392779527811919 0.1247936979625589 0.9006868766871419 1.0 1.0 12 P51530,P35637 2 +Abnormal mitral valve physiology 0.3057784966449029 0.1246617984190913 0.9007913018572702 1.0 1.0 35 Q9NZ08,P09493,P01889,O95235,O75431,Q15056 6 +Abnormality of the musculature of the upper arm 0.3259461938814577 0.124628744853935 0.9008174707095048 1.0 1.0 7 O14979 1 +Proximal upper limb amyotrophy 0.3259461938814577 0.124628744853935 0.9008174707095048 1.0 1.0 7 O14979 1 +Vestibular dysfunction 0.3295599599789046 0.1239109343629567 0.9013857953034836 1.0 1.0 29 Q9NZ08,O15460,Q6UN15 3 +Generalized onset seizure 0.3089455317752357 0.1232841445546325 0.9018820958609576 1.0 1.0 91 O00330,Q9NW15,P00846,Q8WXI9,Q9Y619,Q6PJG6,P07602,Q01105,P49419,P18074,Q9Y263,P03886,P61978,Q08J23 14 +Abnormal glycosylation 0.3440334424952183 0.1218459756878686 0.9030210018576006 1.0 1.0 21 Q96AA3,Q8N511 2 +Delayed cranial suture closure 0.3290214248530443 0.1215962788516575 0.9032187606672788 1.0 1.0 29 Q96T58,P16435,Q9UQE7,Q32P28,P40855,O75431,O75718,P02545,P36543,Q08J23 10 +Macrotia 0.2889477038477897 0.1209010532286094 0.903769407935926 1.0 1.0 75 P35250,P38159,Q8WWQ0,Q9H2M9,O60934,Q9UQE7,Q9UNW1,P48449,Q9NP72,Q01105,Q9UQ13,Q15042,P21281,Q15056,O75175,Q06787 16 +Abnormality of the septum pellucidum 0.3050051259231331 0.1206383427240612 0.9039774975174312 1.0 1.0 35 Q15392,Q9Y5S9,Q8WWQ0,Q6PJT7,O60524,Q08J23 6 +Increased proteinogenic amino acid level in urine 0.3304772758449548 0.1204391560708398 0.9041352750772264 1.0 1.0 9 Q4J6C6 1 +Retinal dystrophy 0.2538927410116898 0.1190407778424464 0.9052430494069652 1.0 1.0 48 P00846,O43172,O75312,Q92620,O43837,P03886 6 +Posterior embryotoxon 0.3425306725532244 0.118238094645302 0.9058790064858092 1.0 1.0 16 Q96DF8 1 +Talipes equinovarus 0.2771325171014862 0.1177341465788739 0.9062783098720808 1.0 1.0 66 Q15392,Q9Y5S9,Q9H2M9,Q96AY3,Q03001,Q9Y619,Q8TD16,O75845,Q9NWM8,P61978 10 +Abnormal aortic valve physiology 0.2940858118915078 0.117514208850121 0.9064525850229276 1.0 1.0 37 Q15477,P35250,Q9NZ08,Q6PGP7,P01889,Q12768,Q01082,Q9UQ13,Q15056 9 +Global brain atrophy 0.3429810196543801 0.1159628901117966 0.907681952722852 1.0 1.0 19 Q9H2M9,P35637 2 +Chronic neutropenia 0.3337870023817644 0.1141923759811699 0.909085295461806 1.0 1.0 5 Q9Y3C6,Q7Z2Z2,Q9Y3A5,P50851 4 +Abnormality of vitamin a metabolism 0.33378700238176 0.114192375981162 0.9090852954618124 1.0 1.0 5 Q9NSD9,Q7Z2Z2,Q9Y3A5,Q13043 4 +Delayed fine motor development 0.3306311517307835 0.1138874824326188 0.9093269885728832 1.0 1.0 10 O75175,Q13509 2 +Decreased facial expression 0.3270620349357511 0.1132552767158492 0.909828173046532 1.0 1.0 29 P51530,Q9BUK6,Q06787,Q9GZZ9,Q9Y263 5 +Abnormality of vitamin e metabolism 0.3336734693877611 0.1132024464809175 0.9098700561261568 1.0 1.0 4 Q13043,Q9Y3A5,Q7Z2Z2 3 +Nyctalopia 0.3297816607304447 0.1126944368969634 0.9102728118665508 1.0 1.0 28 Q13432,Q8WWY3,O43172,O75312,Q92620,Q6P4Q7,P40855,O95140,Q96S66,O43837,P24386 11 +Abnormal basal ganglia mri signal intensity 0.3297431153037726 0.1125365856986855 0.9103979627811478 1.0 1.0 28 P00846 1 +Gastrointestinal hemorrhage 0.3199068031220723 0.1108482364082455 0.9117366938919544 1.0 1.0 31 P22413,Q9NZ08,P01889,Q02241,P25054,P16930 6 +Dyscalculia 0.3288700832757881 0.1094256315415753 0.9128649047835332 1.0 1.0 10 P35637 1 +Median cleft lip 0.5642420122365812 0.1089671063378139 0.9132285802795016 1.0 1.0 2 Q8N3U4 1 +Unilateral ptosis 0.5642420122365811 0.1089671063378139 0.9132285802795016 1.0 1.0 2 Q9UHX1 1 +Abnormal 3rd finger morphology 0.5642420122365743 0.1089671063378064 0.9132285802795076 1.0 1.0 2 Q9Y3E5 1 +Left ventricular hypertrophy 0.3383772064448814 0.1085950105154917 0.9135237183818384 1.0 1.0 23 P00403,P03886,Q07021,Q13724 4 +Inflammation of the large intestine 0.3330320800419512 0.1079186120996956 0.9140602530262416 1.0 1.0 12 Q15477,P42224,O95999,Q6PGP7,P01889 5 +Tall stature 0.2522176577533455 0.1067876371978056 0.91495745547572 1.0 1.0 48 Q5H8A4,P04350,Q9UPY3,P51530,O75175,Q9NWM8,P61978 7 +Decreased number of peripheral myelinated nerve fibers 0.3345068983747431 0.1066554663793327 0.9150623136868248 1.0 1.0 13 Q9H0B6,Q92734,O95140,Q8TB36 4 +Abnormality of cartilage of external ear 0.3834702036136363 0.1062407941241617 0.9153913050503362 1.0 1.0 3 P22413 1 +Decreased proportion of cd3 positive t cells 0.5608429639700959 0.105279529046709 0.916154006148761 1.0 1.0 2 P00491 1 +Recurrent staphylococcal infections 0.5608429639700959 0.105279529046709 0.916154006148761 1.0 1.0 2 P40763 1 +Recurrent staphylococcus aureus infections 0.5608429639700959 0.105279529046709 0.916154006148761 1.0 1.0 2 P40763 1 +Acute coronary syndrome 0.3396163573053571 0.1052703179261695 0.9161613149461983 1.0 1.0 19 P01889,P22413,Q9NZ08,Q15056 4 +Rieger anomaly 0.3821829309758602 0.1045986262494745 0.9166943048212536 1.0 1.0 3 O96028,Q13363 2 +Craniofacial asymmetry 0.3821829309758602 0.1045986262494745 0.9166943048212536 1.0 1.0 3 O96028,Q13363 2 +Noncompaction cardiomyopathy 0.3813718601704354 0.1035746885945964 0.9175068751816408 1.0 1.0 3 Q15233 1 +Hyperextensible skin 0.3362429573088615 0.1030071030877453 0.9179573334957936 1.0 1.0 15 Q9UQ13,Q9NWM8 2 +Spastic tetraparesis 0.3317684634728698 0.1019361154806118 0.918807383251407 1.0 1.0 26 P00846 1 +Abnormal placental size 0.3258202173891685 0.1018187010765757 0.9189005814819068 1.0 1.0 4 Q6PGP7 1 +Abnormal fallopian tube morphology 0.3158943144529307 0.1009504946117686 0.9195897589056924 1.0 1.0 7 Q92878,O60934,Q9NX14 3 +Hypoplasia of the vagina 0.5560842963970164 0.100300754388842 0.920105558598437 1.0 1.0 2 P51809 1 +Female external genitalia in individual with 46 xy karyotype 0.5560842963970164 0.100300754388842 0.920105558598437 1.0 1.0 2 P51809 1 +Gonadoblastoma 0.5560842963970164 0.100300754388842 0.920105558598437 1.0 1.0 2 P51809 1 +Urogenital sinus anomaly 0.5560842963970164 0.100300754388842 0.920105558598437 1.0 1.0 2 P51809 1 +Abnormal sex determination 0.5560842963970164 0.100300754388842 0.920105558598437 1.0 1.0 2 P51809 1 +Ovarian gonadoblastoma 0.5560842963970164 0.100300754388842 0.920105558598437 1.0 1.0 2 P51809 1 +Accessory spleen 0.325961211296358 0.1001241596616756 0.9202457550701276 1.0 1.0 5 O96028,Q13363,O95202,Q15904 4 +Abnormal eyelash morphology 0.2772036541402149 0.0999564968177357 0.920378862919102 1.0 1.0 68 Q96T58,Q13724,Q9UID3,Q03164,Q9UQE7,P48449,Q9Y619,Q9UQ13,P21281,O60885,P20674,Q8WVM7,Q4J6C6 13 +Thromboembolism 0.3226607176116015 0.0975032399341329 0.9223267613965987 1.0 1.0 4 O95235 1 +Meningioma 0.3104076170839489 0.0972159153558751 0.9225549292852472 1.0 1.0 6 P21912,P02545,P21359 3 +Abnormal vitreous humor morphology 0.3100895662410609 0.0965306001374346 0.9230991720027644 1.0 1.0 6 P04439 1 +Neutropenia in presence of anti neutropil antibodies 0.3100748808713509 0.0964990064195069 0.9231242630072471 1.0 1.0 6 P42224,P40763,P29144,P00491,O95394 5 +Large intestinal polyposis 0.3204344089657702 0.0959479979176825 0.9235618735716388 1.0 1.0 9 P21912,Q9UPY3,P25054,Q07864,P42771 5 +Infantile muscular hypotonia 0.270160442903795 0.0952745900194231 0.9240967250535492 1.0 1.0 63 P00846,Q8WXI9,Q13724,P07602,P03886 5 +Midface retrusion 0.2815808387381975 0.0951519485222567 0.924194136264454 1.0 1.0 72 Q96T58,Q9H2M9,O95831,Q8TD16,Q9HC07 5 +Methylmalonic acidemia 0.3093941456773383 0.0950392736229726 0.9242836322467676 1.0 1.0 6 Q4G176,Q96EY8,P53597,P22033,Q9P2R7 5 +Thoracic aortic aneurysm 0.3195406865093502 0.0945834560180332 0.92464569110183 1.0 1.0 30 Q96T58,P01889,Q15056,O75175,Q06787 5 +Abnormal gastrointestinal motility 0.3297713151907153 0.0944499955571899 0.9247517025618226 1.0 1.0 26 P00403,P03886,P61978,P35637 4 +Joint hypermobility 0.3000211438588878 0.0942612584377583 0.9249016241329324 1.0 1.0 87 Q8WWQ0,Q5H8A4,P22413,P35250,O75175,Q03164,Q9Y619,Q01105,Q15042,P21281,Q15056,Q9Y263,Q8N0X7,Q9NWM8,O75179,Q08J23 16 +Conjugated hyperbilirubinemia 0.3721386602489295 0.0924975736187824 0.9263027189297952 1.0 1.0 3 Q9Y5L0 1 +Achilles tendon contracture 0.3269451855621856 0.0922942827447936 0.9264642306921812 1.0 1.0 12 Q8TD16,Q08J23 2 +Abnormal synaptic transmission at the neuromuscular junction 0.3245224197654199 0.0916022384298722 0.92701407292009 1.0 1.0 28 Q15165,P11310,Q92804,P50995,P35637 5 +Cardiac valve calcification 0.3178023062416677 0.0911592408220892 0.9273660611683624 1.0 1.0 4 O75431 1 +Mitral valve calcification 0.3178023062416677 0.0911592408220892 0.9273660611683624 1.0 1.0 4 O75431 1 +Neoplasm of the skeletal system 0.2837099765366273 0.0907004237548824 0.92773063391314 1.0 1.0 38 O75874,P48735 2 +Rod cone dystrophy 0.294146609034695 0.0900755979410478 0.9282271403997124 1.0 1.0 36 P00846 1 +Ophthalmoparesis 0.2795885865351257 0.0900131533333869 0.9282767624123642 1.0 1.0 71 P00846,Q07021,O43172,P01889,Q13509,Q92620,P00403,O15460,P51530,O43837,P03886,Q86U42 12 +Laryngomalacia 0.3280179686142026 0.0896610149407219 0.9285565966867362 1.0 1.0 13 P25054,P07602,P02545,P36543 4 +Neoplasm of the male external genitalia 0.320716448639494 0.089627205096899 0.9285834648647138 1.0 1.0 10 Q9UPY3,Q01844,P10644 3 +Large beaked nose 0.3192194032046244 0.0888373282870098 0.9292111912751102 1.0 1.0 5 P18074 1 +Shoulder dislocation 0.3155263186070821 0.0883077250478484 0.9296320992447542 1.0 1.0 4 Q6ZXV5 1 +Osteopenia 0.2704192272650919 0.0880811158764789 0.9298122053838832 1.0 1.0 64 Q8WWQ0,Q96AY3,P07602,O75431,P18074,Q15056,Q5JRA6,Q32P28,Q9NWM8,P61978 10 +Abnormal macroscopic urine appearance 0.3338633842150765 0.0874768662572725 0.930292472982662 1.0 1.0 20 Q8N1F7,Q8NFH4,Q12965,P23786,Q9Y5K6 5 +Vertebral clefting 0.3097241927764588 0.0874365982496508 0.930324479565823 1.0 1.0 7 O75845,Q9Y2W2 2 +Large basal ganglia 0.3267836429134084 0.0865356475997198 0.931040619656044 1.0 1.0 13 O60524,Q13509,Q08J23 3 +Hirsutism 0.2532606160491992 0.085979080777224 0.9314830467573104 1.0 1.0 51 Q96T58,Q13724,Q9H2M9,Q9UQE7,Q03164,Q9NP72,Q15042,O60885,Q03252,P54802,Q9Y263 11 +Melanocytic nevus 0.321846317269197 0.0858090406444662 0.9316182195945676 1.0 1.0 11 Q96AY3,P18074 2 +Allergy 0.3085805982542259 0.0850176231006972 0.932247380225721 1.0 1.0 7 Q9Y5S9 1 +Abnormal morphology of myocardial trabeculae 0.3119047619047659 0.0839268238083074 0.93311461247874 1.0 1.0 4 Q99797,P14923,Q15233 3 +Exercise induced myalgia 0.318211335443322 0.0838301076861608 0.9331915097937348 1.0 1.0 10 P23786 1 +Ketotic hypoglycemia 0.364161849710987 0.0837693614300836 0.9332398084095128 1.0 1.0 3 P53985,Q13423 2 +Thyroid adenoma 0.3098639455782383 0.0815418958240199 0.9350110077404136 1.0 1.0 4 Q6P1J9,P20585,P10644 3 +Deviation of the hand or of fingers of the hand 0.3027891547308901 0.079883061225321 0.9363302619552768 1.0 1.0 91 P35250,Q9Y5S9,Q9H2M9,Q9Y2U8,Q03164,Q15042,O75175,Q03252,Q08J23,Q9NP72,P21281,Q13724,Q9ULC3,Q9UQE7,Q8TD16,O60885,Q5JRA6,Q96T58,Q9Y619,Q6PJG6,Q15056,Q8WVM7 22 +Onycholysis 0.3133718952024444 0.0796671056110768 0.9365020221883285 1.0 1.0 5 P10321,P20810,O15446,P06132 4 +Aplasia cutis congenita of scalp 0.3015288027141113 0.0788530898034848 0.9371494759133264 1.0 1.0 6 Q5H8A4 1 +Increased hepatocellular lipid droplets 0.5326308633582681 0.0787845594595316 0.9372039856351696 1.0 1.0 2 P42704 1 +Overriding aorta 0.3122871312649566 0.0776379356370325 0.938116065165142 1.0 1.0 9 Q15056,P35250,Q9NX14,P78347 4 +Abnormality of blood circulation 0.2700908262036465 0.0769310442530915 0.938678400979034 1.0 1.0 65 O00330,P22413,Q9NZ08,Q8NBJ5,P01889,Q6UN15,Q02241,P23786,P25054,P16930,P36543 11 +Abnormality of the nasal septum 0.2996002254187427 0.0750753282090524 0.940154777651376 1.0 1.0 6 P21359,P21281 2 +Abnormal electroretinogram 0.3116137865648274 0.0750048524755446 0.940210851053495 1.0 1.0 31 P00846,Q8WWY3,O43172,Q92620,Q15067,Q96S66,O43837,P24386 8 +Curly hair 0.3171176198622131 0.0748331460422196 0.9403474690184476 1.0 1.0 11 Q9UQ13,Q6PGP7 2 +Degeneration of the striatum 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Csf lymphocytic pleiocytosis 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Csf pleocytosis 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Chilblains 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Moyamoya phenomenon 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Neonatal alloimmune thrombocytopenia 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Chronic leukemia 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Chronic lymphatic leukemia 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Multifactorial inheritance 0.3217760573150051 0.0742106006095307 0.940842811044858 1.0 1.0 13 O60934,P01889,P22413,P35611 4 +Generalized lipodystrophy 0.3018065650521941 0.0727046089643939 0.9420411808352258 1.0 1.0 4 O75431 1 +Abnormality of epiphysis morphology 0.2486652588760297 0.0722977091469251 0.9423649877635304 1.0 1.0 49 P82673,Q9Y2U8,O95831,Q9Y619,Q9HC07,Q5JRA6 6 +Lack of peer relationships 0.5234534330387577 0.0716649216056077 0.942868572858088 1.0 1.0 2 Q96CW1 1 +Hand apraxia 0.5234534330387576 0.0716649216056077 0.942868572858088 1.0 1.0 2 Q14683 1 +Corneal ulceration 0.3075876148349767 0.0711558963137965 0.9432736820408713 1.0 1.0 5 O95163,O75844,P02545,P06132 4 +Allergic rhinitis 0.5224337185588108 0.0709166291895574 0.9434641085177844 1.0 1.0 2 O95394 1 +Thoracic kyphosis 0.3200871542526918 0.070182393496619 0.9440484877210932 1.0 1.0 13 O95831,P18074 2 +Abnormal parotid gland morphology 0.5203942895989211 0.0694451573593214 0.944635285280709 1.0 1.0 2 P16615 1 +Ectropion 0.3117024869669017 0.0693994014377292 0.9446717053558648 1.0 1.0 10 O60716,P61978,P18074 3 +Myoclonus 0.2951243732600565 0.0689524959971555 0.945027432153204 1.0 1.0 86 P00846,Q5THJ4,Q9NWS8,Q8NC96,Q9UNW1,Q03252,Q6PJG6,P00403,P07602,Q01105,P21281,O75845,Q9Y4G8,Q96AA3,Q9GZZ9,P03886 16 +Chorioretinal degeneration 0.2951230375003882 0.0665948875714421 0.9469042158392722 1.0 1.0 6 Q9Y619 1 +Osteolytic defects of the distal phalanges of the hand 0.2941277807518834 0.0651177316025913 0.948080262617936 1.0 1.0 4 O75431 1 +Airway obstruction 0.3154138109515679 0.0649494155519028 0.9482142757009332 1.0 1.0 12 Q86Y56,P09601,P25054,P02545,Q96HY6 5 +Onion bulb formation 0.3023451845670992 0.0645453228265751 0.9485360199265248 1.0 1.0 8 Q5TAQ9,O95140,Q8TB36 3 +Bowel diverticulosis 0.302225852558554 0.064311494217803 0.9487222013402568 1.0 1.0 8 Q15056,P35250,P78347,P43246 4 +Color vision defect 0.3196557077439452 0.0641776994973872 0.9488287340051398 1.0 1.0 14 Q6P4Q7,Q8WWQ0,A2RRP1,O00429 4 +Abnormality of the dorsal column of the spinal cord 0.3427405644338613 0.0639974227354141 0.9489722789620668 1.0 1.0 3 Q6PI48,Q8WVX9 2 +Bilateral coxa valga 0.5112168592794091 0.0632284086897992 0.9495846231698396 1.0 1.0 2 Q96A33 1 +Truncal obesity 0.321058511048495 0.063131430841266 0.949661846018676 1.0 1.0 15 Q9UQE7,O60216,P10644,O60885,Q06787,P31751 6 +Neoplasm of the ear 0.340360421625292 0.062113522133747 0.9504724286863642 1.0 1.0 3 Q9UJX6,P10644 2 +Wide nose 0.2930231113406277 0.0615929319876853 0.950887005713847 1.0 1.0 35 Q15477,Q5H8A4,Q6PGP7,Q13724,Q9Y2U8,Q03164,Q9Y2W2,P21281 8 +Ischemic stroke 0.5084976206662224 0.0615101674524721 0.9509529172842588 1.0 1.0 2 P31153 1 +Agenesis of corpus callosum 0.2841570476691923 0.0613553114575141 0.9510762415601934 1.0 1.0 78 O00330,Q96T58,Q15392,Q5H8A4,P78318,Q9H2M9,Q13509,P23786,P00403,Q15042,P18074,P03886,P61978 13 +Hyperostosis 0.315758368927048 0.0601550615154846 0.9520321365754288 1.0 1.0 13 P22626,Q9Y2U8,Q15043,P18074 4 +Spina bifida occulta 0.3235982561460413 0.0600899223953177 0.9520840162238736 1.0 1.0 18 P35250,Q9Y2W2,P21281,Q15056,Q08J23 5 +Abnormal protein glycosylation 0.3225100789499895 0.0597454034207785 0.9523584095974232 1.0 1.0 17 Q8N511 1 +Exercise intolerance 0.3043760433554778 0.0590779258254002 0.9528900405660488 1.0 1.0 32 Q9H2D1,Q07021,Q8IUX1,P23786,P00403,P51530,P03886 7 +Primary microcephaly 0.319279166948425 0.0588162671718325 0.9530984515614972 1.0 1.0 15 Q03252,Q5SRE5,Q13509 3 +Arthritis 0.271951104809927 0.0571812679190426 0.9544007997776716 1.0 1.0 39 Q9NZ08,P28070,P01889,Q9Y2U8,O15460,Q7Z406 6 +Phimosis 0.3315198911934698 0.0556296859360649 0.9556368151585932 1.0 1.0 3 Q9UJX6,O60828 2 +Abnormal talus morphology 0.3225813755098906 0.0555715364408994 0.955683140082546 1.0 1.0 19 P98175,Q5SRE5,Q9UPT5,P18074,P02545,Q9Y263 6 +Inability to walk 0.290650554266547 0.0553547359953674 0.955855855955288 1.0 1.0 84 Q99720,P00846,Q96D71,P35637,Q9BUK6 5 +Glomerular sclerosis 0.3034554500912994 0.0552632546926644 0.9559287359160008 1.0 1.0 32 Q8N1F7,Q8NFH4,Q12965,Q9Y5K6,P00403,O75431,P16930,P52565,P03886 9 +Decreased pulmonary function 0.330159809588575 0.0547019688967202 0.9563759007605824 1.0 1.0 3 Q9UMX1,Q969G3 2 +Eeg with irregular generalized spike and wave complexes 0.4966009517335237 0.0546250855013773 0.9564371532519744 1.0 1.0 2 Q96CW1 1 +Cough 0.322303379264438 0.054047632943703 0.9568972140734509 1.0 1.0 22 O15460,P35610,Q6UN15 3 +Absent hypoplastic paranasal sinuses 0.3287997279836751 0.0537923543503057 0.9571006010461168 1.0 1.0 3 P04066,P10644 2 +Abdominal wall muscle weakness 0.3287997279836737 0.0537923543503046 0.9571006010461176 1.0 1.0 3 P46976,P21359 2 +Abnormal ovarian morphology 0.3202903923173948 0.051987310127841 0.9585388047920274 1.0 1.0 24 P16435,P35250,P21912,Q8WWQ0,P78347,O75312,Q9BW83,P10644,Q15056,Q03252,P02545,P31751 12 +Neoplasm of the genitourinary tract 0.2637967140203812 0.0516828857859051 0.958781374177362 1.0 1.0 63 P62899,O95999,Q01844,Q92878,O60934,O75874,Q9UNW1,Q9UPY3,P48735,Q92733,P25054,P42766 12 +Slender build 0.3027230532100655 0.0509901045621351 0.9593334057075072 1.0 1.0 10 P04350 1 +Polycystic liver disease 0.323536802850723 0.0504396776565817 0.9597720184129466 1.0 1.0 3 Q9UGP8 1 +Cystic liver disease 0.323536802850723 0.0504396776565817 0.9597720184129466 1.0 1.0 3 Q9UGP8 1 +Progressive spastic paraplegia 0.3134061042252032 0.0500549297963303 0.9600786154972872 1.0 1.0 28 O75298,P00846 2 +Lissencephaly 0.2480010885733853 0.050013690476991 0.9601114785525132 1.0 1.0 51 Q15392,P11177,Q9BSJ2,Q9H2M9,Q9NWS8,Q13509,P23786,Q15042 8 +Pituitary growth hormone cell adenoma 0.3223393403604184 0.0497131909314607 0.9603509446146514 1.0 1.0 3 O00170,P10644 2 +Neurogenic bladder 0.2905750255188785 0.0492658043102072 0.9607074706184532 1.0 1.0 5 Q8TAA9,Q9H270,O76024,Q9BTW9 4 +Broad neck 0.3017544187797049 0.0491079059372452 0.9608333029841216 1.0 1.0 10 Q07864,P78318 2 +Gaze evoked nystagmus 0.2932561307901912 0.0475809816407134 0.9620501893121576 1.0 1.0 8 Q9UNE7,Q9Y4W6,P31040,P49959,O15020,Q9UBB4,P35251 7 +Reduced consciousness confusion 0.3271131093316882 0.0469948584729279 0.9625173253471826 1.0 1.0 116 Q16836,A2RRP1,O43772,P01889,P07602,O96000,P35610,P03886,P20674,O00330,Q9Y5L0,Q9NZ08,O43676,Q9NPL8,P18074,Q5H8A4,P11310,P00403,P11182,P31751,P62899,Q9NWS8,P23786,Q9Y619 24 +Microvesicular hepatic steatosis 0.2929155313351496 0.0469784391367057 0.9625304116284896 1.0 1.0 8 P54577,Q9H845,P42704,Q9Y276,Q9UN37,Q9H3U1,Q9H9J2 7 +Neoplasm of the respiratory system 0.3070188489909125 0.0469126861667337 0.9625828171283488 1.0 1.0 12 Q01844,Q9UPY3,P30154,P02545,P42771 5 +Hypothalamic hamartoma 0.4789259007478003 0.0461563105355631 0.9631856644780136 1.0 1.0 2 O43924 1 +Peritonitis 0.315587142343364 0.0460495903070878 0.9632707244558204 1.0 1.0 16 Q8N1F7,Q8NFH4,Q12965,Q9Y5K6,P52565 5 +Lack of skin elasticity 0.3092797439610542 0.0459479065704804 0.9633517705518344 1.0 1.0 13 Q96T58,P22413,Q13620,P10644,Q15334 5 +Abnormality of cardiovascular system electrophysiology 0.3166055559128087 0.0457527375882915 0.9635073292714408 1.0 1.0 107 Q16836,P00846,P09493,O43772,Q9H2M9,Q03001,P23786,Q6PJG6,P00403,P07602,O15460,P11310,Q15056,P03886 14 +Parietal cortical atrophy 0.4765465669612599 0.0451640795415144 0.963976525392124 1.0 1.0 2 Q6P3W7 1 +Median cleft palate 0.4755268524813151 0.0447489467743274 0.9643074188639362 1.0 1.0 2 Q8N3U4 1 +Giant platelets 0.4755268524813151 0.0447489467743274 0.9643074188639362 1.0 1.0 2 P35579 1 +Axonal regeneration 0.3121387283236931 0.0440460538467874 0.9648676938053724 1.0 1.0 3 P54577,Q8TB36 2 +Abnormality of hair texture 0.2404271322328301 0.0434492623271294 0.9653434090943362 1.0 1.0 46 Q15477,A2RRP1,Q8WXI9,Q9UQ13,P54802,Q08J23 6 +Facial asymmetry 0.3091324944878707 0.0430283577440998 0.965678928570874 1.0 1.0 29 A2RRP1,Q9UQE7,Q03164,Q01105,P61586,P21359,O60716,Q00577 8 +Open bite 0.3117093374723844 0.0413032078108193 0.9670541757911222 1.0 1.0 15 P35250,P78347,O43709,Q13620,P21281,P10644,Q15056,P61978 8 +Pain in head and neck region 0.2824486694271558 0.0404009758803441 0.9677734522459828 1.0 1.0 5 Q15043 1 +Open operculum 0.4632902787219658 0.0402186442145558 0.9679188137213386 1.0 1.0 2 P07954 1 +Enlarged cisterna magna 0.3145948045053956 0.0401829125579147 0.9679473004304782 1.0 1.0 17 O75175,P49419,Q9UID3 3 +Abnormal pulmonary valve physiology 0.2883119729231727 0.04013946874513 0.9679819356347644 1.0 1.0 35 P35250,P22413,Q6PGP7,O95235,Q12768,P55263,Q9ULC3,Q9UQE7,Q9UQ13,Q15056 10 +Abnormal thyroid hormone level 0.4622705642420179 0.03987707086154 0.968191131361464 1.0 1.0 2 O14654 1 +Distal joint laxity 0.459551325628834 0.0389918621617266 0.9688968767354668 1.0 1.0 2 O75340 1 +Primary amenorrhea 0.3145259200612829 0.0373271563392198 0.9702241529491028 1.0 1.0 25 Q9BUK6 1 +Minimal change glomerulonephritis 0.3097686134059005 0.0370337067800331 0.9704581300418575 1.0 1.0 15 Q8N1F7,Q8NFH4,Q9Y5K6,Q12965 4 +Abnormal eating behavior 0.3160316349738556 0.0369121393554292 0.9705550605384884 1.0 1.0 20 Q96T58,Q4J6C6 2 +Agenesis of cerebellar vermis 0.2927575654539214 0.035616966511255 0.9715877795853772 1.0 1.0 3 O43924,Q03426 2 +Papilloma 0.2814145292350777 0.0354091145713655 0.9717535168939292 1.0 1.0 7 Q13043,P18074 2 +Variable expressivity 0.2752093093861658 0.0353341235358839 0.971813313664214 1.0 1.0 74 O00330,P04350,Q70HW3,Q13509,P07602,Q8TD16,P00403,P03886 8 +Abnormality of the periungual region 0.4449354180829424 0.0348340113959051 0.9722120999083226 1.0 1.0 2 P40763 1 +Paronychia 0.4449354180829424 0.0348340113959051 0.9722120999083226 1.0 1.0 2 P40763 1 +Abnormal femoral neck morphology 0.2911055547632933 0.0345267877233903 0.9724570815646584 1.0 1.0 34 Q9Y5S9,Q96AY3,O95831,Q9Y619,O75431,Q96HY6 6 +Calcinosis 0.2762844504933615 0.0343280508530757 0.9726155567009442 1.0 1.0 5 Q14739,Q9H1A4,O75844,P02545 4 +Hypoventilation 0.2997278951409053 0.0325251363226018 0.974053270744578 1.0 1.0 12 P61978 1 +Prominent nose 0.3110817361761708 0.0320035127130393 0.974469249593916 1.0 1.0 17 Q15233,O60934,Q13620,P40855,Q12797,Q8N0X7,Q08J23 7 +Abnormal cranial nerve physiology 0.2632409256430478 0.0314434347074275 0.9749159023741074 1.0 1.0 65 Q96T58,Q9NZ08,O75874,Q13509,P07602,P48735,P51530 7 +Functional abnormality of the middle ear 0.2832806428460735 0.0313800552667429 0.9749664469090528 1.0 1.0 81 Q96T58,P22413,P78318,O75175,P01889,O43172,O60885,Q9ULC3,O95831,Q9UQE7,Q92620,O15460,O75845,O43837,O60716,Q9NWM8,P61978 17 +Abnormality of the nasal bone 0.2788167290037347 0.0311767211136335 0.975128604748266 1.0 1.0 3 Q6NUK1,P10644 2 +Abnormal blood chloride concentration 0.4276002719238677 0.0310571821020324 0.9752239369154204 1.0 1.0 2 Q13618 1 +Abnormality of the incisor 0.3138132090684191 0.030709596725142 0.9755011376934836 1.0 1.0 23 Q9BSJ2,Q8WXI9,P21281,O75175,Q8WVM7 5 +Transposition of the great arteries 0.2730213572229246 0.0305810967034721 0.9756036177440486 1.0 1.0 6 Q9ULC3,Q86Y56 2 +Abnormality of the clitoris 0.3128165124636064 0.0305003293895061 0.9756680306897468 1.0 1.0 19 Q9H2M9,Q9UNW1,Q9Y619,Q9NP72,Q15042 5 +Chronic constipation 0.3131406464932185 0.030411103844213 0.975739189365449 1.0 1.0 24 P78318,Q8WXI9 2 +Obstructive sleep apnea 0.294911735574093 0.0298460483652245 0.976189833823722 1.0 1.0 11 P51530 1 +Papillary thyroid carcinoma 0.2911695205917314 0.0298447842041047 0.9761908420292328 1.0 1.0 10 P51532,Q8TAQ2,Q9UNW1,Q9UPY3,Q96GM5,P25054 6 +Adult onset 0.2603803792079227 0.02948038428668 0.9764814632132974 1.0 1.0 63 O00330,Q9Y5L0,P22413,O14979,Q07021,Q06787,Q12768,Q5THJ4,P07602,Q14566,Q9UJV9,P31483,P17096,Q9Y4G8,Q07864,P31751,Q86U42 17 +Anterior pituitary dysgenesis 0.4095853161114974 0.0282132733634425 0.9774920508257569 1.0 1.0 2 Q15233 1 +Abnormal response to acth stimulation test 0.4095853161114974 0.0282132733634425 0.9774920508257569 1.0 1.0 2 P16435 1 +Adrenocorticotropin deficient adrenal insufficiency 0.4095853161114927 0.0282132733634417 0.9774920508257574 1.0 1.0 2 O00170 1 +Abnormal serum insulin like growth factor 1 level 0.4095853161114927 0.0282132733634417 0.9774920508257574 1.0 1.0 2 O00170 1 +Keloids 0.2640120288032505 0.027674819451271 0.9779215071763268 1.0 1.0 3 P25054 1 +Elevated urinary delta aminolevulinic acid 0.2631757905474265 0.0275093247157619 0.9780535026154236 1.0 1.0 3 P16930,P36551 2 +Hypersomnia 0.4031271244051704 0.0274148438610878 0.9781288590096552 1.0 1.0 2 O00170 1 +Abnormality of malar bones 0.2523008689282517 0.0271869299694369 0.9783106402277146 1.0 1.0 57 Q9Y5S9,Q96MF7,Q15233,Q9H2M9,O60934,Q9ULC3,O95831,Q14320,P61586,Q15042,Q9HC07,P10644,P21359,P25054,O75175,P02545,P36543,Q07864 18 +Dental crowding 0.3126247756093242 0.0271366932353731 0.9783507085589922 1.0 1.0 21 Q96T58,Q92643,Q69YQ0,Q01105,O75431 5 +Emg axonal abnormality 0.3936097892590152 0.0264172814590437 0.9789245103489728 1.0 1.0 2 Q92734 1 +Anteverted ears 0.3783140720598306 0.0251918835222588 0.9799019109142406 1.0 1.0 2 O15347 1 +Spondyloepiphyseal dysplasia 0.3783140720598292 0.0251918835222585 0.9799019109142408 1.0 1.0 2 Q9NSE4 1 +Abnormality of the gingiva 0.2362689590010609 0.0250953725700745 0.9799788911755218 1.0 1.0 45 Q15392,Q6UN15,Q02241,P21281,O75845,Q5JRA6,Q15056 7 +Facial erythema 0.3721957851801562 0.0248106913193228 0.9802059632448308 1.0 1.0 2 O00170 1 +Exanthem 0.3596193065941612 0.0241853323589236 0.9807047777912876 1.0 1.0 2 Q03426 1 +Atrial flutter 0.349762066621352 0.0238183789635271 0.9809974799149752 1.0 1.0 2 P02545 1 +Renal hamartoma 0.3416043507817868 0.0235805709355996 0.9811871699898173 1.0 1.0 2 Q03426 1 +Abnormal chromosome morphology 0.34126444595514 0.0235717897872764 0.9811941743855712 1.0 1.0 2 O95453 1 +Sensory axonal neuropathy 0.2979650410406046 0.0234291364256051 0.9813079638745992 1.0 1.0 13 Q9H0B6,P22626,Q15067,O95831 4 +Lacrimal duct atresia 0.328687967369143 0.0233007981321584 0.9814103350702874 1.0 1.0 2 Q9NX14 1 +Homocystinuria 0.3089734874235276 0.0230391243554102 0.981619064500711 1.0 1.0 2 Q99707 1 +Decreased methylcobalamin 0.2627464309993276 0.0228258892733344 0.9817891567485724 1.0 1.0 2 Q99707 1 +Cutaneous melanoma 0.262406526172679 0.0228253417409384 0.9817895935024266 1.0 1.0 2 P42771 1 +Cutis laxa 0.3053015639525249 0.0224475268403327 0.9820909689531574 1.0 1.0 28 Q15056,O96000 2 +Colorectal polyposis 0.2751616893621538 0.0188238788571477 0.9849816046230986 1.0 1.0 8 P21912,Q07864,Q9UPY3,P42771 4 +Abnormal blood transition element cation concentration 0.2915583439066136 0.0178000527246243 0.985798362699075 1.0 1.0 12 Q02241,Q15477,Q10567,Q6PGP7 4 +Impaired smooth pursuit 0.2937563971340822 0.0157902828855501 0.9874017006057862 1.0 1.0 13 P13639,P46977,P11177,Q9BTW9,O00567,P54136,P49959,O15020,P43034,Q9UBB4,P35251,O00754 12 +Increased body weight 0.2905001958997258 0.0153464937282417 0.9877557502108134 1.0 1.0 89 P35250,O75312,Q01082,Q9UQ13,P50402,O00330,P51114,Q06787,P38159,Q9ULC3,Q9UQE7,Q92620,O43837,Q5JRA6,P31751,Q96T58,Q8WWQ0,P22413,O43172,Q15056 20 +Blue irides 0.277250531162083 0.0148026380408733 0.9881896349603864 1.0 1.0 9 Q15056,P35250,P78347,P10644 4 +Iron deficiency anemia 0.2509870981039193 0.0147921265131069 0.9881980210279342 1.0 1.0 5 P25054,Q10471 2 +Absent septum pellucidum 0.3028130335173204 0.0144342911007546 0.9884835018939782 1.0 1.0 28 O60524,Q15392,Q08J23,Q8WWQ0 4 +Macular thickening 0.266508265786717 0.0144249708253983 0.9884909376236346 1.0 1.0 7 P25054,P04439 2 +Abnormality of the pubic bone 0.2659469621803381 0.0137171645244074 0.9890556294256192 1.0 1.0 7 Q5H8A4 1 +Avascular necrosis 0.3059358565750232 0.0120959704515385 0.990349047271869 1.0 1.0 20 Q9Y619,Q9NZ08 2 +Short clavicles 0.2696276718791172 0.0113197365491463 0.9909683498560682 1.0 1.0 8 Q8NC56,Q14839,O75431 3 +Abnormality of the phalanges of the toes 0.2871629961541061 0.0104792715329689 0.9916389040648051 1.0 1.0 12 O75431,P21281 2 +Arnold chiari malformation 0.3058511658600061 0.0102879805406845 0.991791523966 1.0 1.0 21 P16435,P35250,P78347,Q15233,Q14839,O43709,Q8TAA9,Q9Y2U8,O75845,Q15056,Q15043 11 +Young adult onset 0.2786187020904235 0.0100462519479844 0.9919843855092196 1.0 1.0 10 Q14566,P07602,O15118,P31483 4 +Mask like facies 0.2902081407712342 0.0096564228693039 0.9922954090178786 1.0 1.0 13 Q06787,Q9GZZ9 2 +Pes planus 0.2621668568184509 0.0088185815604225 0.992963881121632 1.0 1.0 67 Q96T58,P35250,Q5H8A4,Q8WWQ0,P21281,Q15056,O75175,Q06787,Q9NWM8,P61978,Q15334 11 +Coronal craniosynostosis 0.2363201608912112 0.0069404214231606 0.9944623893583064 1.0 1.0 5 P16435,Q9ULC3 2 +Unsteady gait 0.2333194230225422 0.00668823755528 0.9946635983008072 1.0 1.0 45 O00330,Q5THJ4,O95831,Q8NC96 4 +Lower limb muscle weakness 0.2448906356505472 0.0061979217420695 0.9950548055939344 1.0 1.0 42 Q12768,O75298,Q8N0X7,P00846 4 +Abnormality of ocular smooth pursuit 0.302240828324169 0.0061873013807164 0.9950632792538108 1.0 1.0 19 Q06787,P11177,Q9NW15 3 +Generalized limb muscle atrophy 0.2653423477592015 0.005908096963656 0.9952860480728828 1.0 1.0 8 Q6PI48,Q9Y2U8 2 +Pseudobulbar paralysis 0.2636239782016361 0.0038339879961636 0.9969409276660132 1.0 1.0 8 P42356,Q15233,P54886,P20700,O94979,Q14203,P54136 7 +Hypodontia 0.2502485035163601 0.0027498284246195 0.9978059571202028 1.0 1.0 41 P35250,Q5H8A4,Q9Y2U8,Q8NC96,Q15067,O75431,P21281,P25054,Q15056,Q9GZZ9 10 +Aplasia hypoplasia of the clavicles 0.281970092088656 0.0023625336259478 0.998114972649046 1.0 1.0 12 Q9Y619,Q8NC56,Q14839,O75431 4 +Abnormality of the pulmonary vasculature 0.2660971976757738 0.0018396106527227 0.998532203890182 1.0 1.0 38 Q96DF8,O75175,Q15392,Q15056 4 +Rimmed vacuoles 0.288744451758943 0.0016798355905513 0.9986596857479724 1.0 1.0 14 Q9Y5L0,O14979,P31483,P50402,P22626,P02545,Q86U42 7 +Abnormality of prothrombin 0.281425134126626 0.0015437535488272 0.9987682633669468 1.0 1.0 12 A2RRP1 1 +Nail dystrophy 0.3011887097962042 0.0012224719429532 0.9990246087536464 1.0 1.0 26 P18074,P21281,Q03001 3 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b4cb08b566aef74c752406cc42e8069b5a5436a3 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal energy expenditure", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pulse", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of falx cerebri", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalomalacia", "Encephalopathy", "Enchondroma", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal bleeding", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long toe", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low serum calcitriol", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphadenitis", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orbital cyst", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic calcification", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent spontaneous abortion", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skewfoot", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Stapes ankylosis", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth abscess", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APOL2", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "ATXN10", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCL10", "BCS1L", "BICD2", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRD4", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CAPN1", "CARS", "CASK", "CAST", "CBFB", "CBL", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CD320", "CD3EAP", "CDC42", "CDC45", "CDC73", "CDH2", "CDK4", "CDK5", "CDKN2A", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHM", "CHMP1A", "CHMP2B", "CHORDC1", "CHST14", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT3", "CNP", "COA3", "COA7", "COG4", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREB1", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DICER1", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJC13", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTNBP1", "DYNC1H1", "DYNC1I2", "DYNC2H1", "EARS2", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "ENPP1", "EPB41", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERGIC1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EZR", "FAH", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GIGYF2", "GINS1", "GIPC1", "GLA", "GLB1", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNAI3", "GNS", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GRHPR", "GSDME", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFT27", "IGBP1", "IGF2BP2", "IGF2R", "IKBKB", "INF2", "INTS1", "IRF2BPL", "IRS4", "ISCU", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KIAA0319L", "KIF11", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMC1", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPP", "LRBA", "LRPPRC", "LSS", "LYRM7", "LZTFL1", "MACF1", "MAGED2", "MAN2B1", "MAP1B", "MAP2K1", "MAPK1", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MFN2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS14", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVK", "MYH14", "MYH9", "MYO1E", "MYO6", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEK9", "NEMF", "NF1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NT5C2", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC6", "OSGEP", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGT", "PIGU", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PSPH", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "RAB18", "RAB23", "RAB33B", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RANGRF", "RAPGEF2", "RARS", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RTN2", "SAR1B", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SHOC2", "SIGMAR1", "SKIV2L", "SLC12A2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC33A1", "SLC39A14", "SLTM", "SMARCA4", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUFU", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP2", "TAPBP", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL2", "TCOF1", "TDP2", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM22", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TKT", "TMCO1", "TMEM106B", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TSFM", "TTC19", "TTC37", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "UBA1", "UBA5", "UBE3A", "UBE4B", "UBR7", "UBTF", "UFD1", "UFM1", "UGDH", "UGP2", "UMPS", "UNC119", "UNC45A", "UNG", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS11", "VPS13A", "VPS13D", "VPS16", "VPS33B", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WASHC5", "WBP11", "WDR1", "WDR26", "WDR36", "WDR45B", "WFS1", "WIPI2", "XPNPEP3", "YARS", "YARS2", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZPR1"], "leading_proteins": ["AARS2", "ACAD9", "ACADM", "ACBD5", "ACOX1", "ACSF3", "ADAR", "ADD1", "ADK", "AFG3L2", "AIFM1", "AIP", "AKT2", "ALDH18A1", "ALDH7A1", "ANAPC1", "ANAPC2", "ANKRD17", "ANO10", "ANXA11", "AP1B1", "AP2M1", "APC", "ARHGDIA", "ASCC1", "ASPH", "ATP2A2", "ATP2B4", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATXN10", "B4GAT1", "BAG3", "BCL10", "BCS1L", "BICD2", "BRAT1", "BRD4", "BUD23", "C1QBP", "CALR", "CAMK2G", "CAST", "CBFB", "CCDC47", "CD2AP", "CD3EAP", "CDC73", "CDKN2A", "CHAMP1", "CHD4", "CHM", "CLCC1", "CNNM4", "CNOT3", "COLGALT1", "COX15", "COX2", "COX5A", "CPOX", "CPT2", "CREB1", "CRTAP", "CTBP1", "CTNND1", "CTPS1", "CUL3", "CUL4B", "DARS2", "DBT", "DCAF8", "DCTN1", "DDRGK1", "DDX41", "DHCR24", "DHX37", "DHX38", "DIABLO", "DICER1", "DNA2", "DNAAF5", "DNM1L", "DST", "DTNBP1", "EEF2", "EFL1", "EIF4H", "ELP1", "EMC1", "EMD", "ENPP1", "EPHX2", "ERAP1", "ERCC2", "ERLIN2", "ESS2", "EWSR1", "EXOC7", "FAH", "FAM50A", "FAR1", "FARSA", "FARSB", "FH", "FIP1L1", "FKBP10", "FKBP14", "FMR1", "FOXRED1", "FUCA1", "FUS", "FXR1", "GALNT2", "GATAD2B", "GDAP1", "GFPT1", "GLMN", "GNAI3", "GTF2I", "GYG1", "HADH", "HELLS", "HLA-A", "HLA-B", "HLA-C", "HMGA1", "HMGB3", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPK", "HYOU1", "IARS2", "IDH1", "IDH2", "IDH3B", "IFT27", "IGBP1", "IKBKB", "INTS1", "IRS4", "JUP", "KIF20A", "KIF23", "KIF2A", "KLC2", "KMT2A", "LAS1L", "LBR", "LEMD2", "LEMD3", "LETM1", "LLGL1", "LMNA", "LMNB1", "LMNB2", "LRBA", "LRPPRC", "LSS", "MAN2B1", "MAP1B", "MAT2A", "MCM4", "MCM6", "MECP2", "MFN2", "MIA3", "MINPP1", "MIPEP", "MMAB", "MOGS", "MORC2", "MRE11", "MRPL44", "MRPS22", "MRPS35", "MSH2", "MSH3", "MSMO1", "MSTO1", "MTAP", "MTR", "MTX2", "MUT", "MVK", "MYH14", "MYH9", "MYO1E", "NADK2", "NAGLU", "NBAS", "NBN", "NCSTN", "ND1", "NDUFA13", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFS3", "NECAP1", "NEK9", "NEMF", "NF1", "NNT", "NONO", "NOP56", "NPC1", "NPM1", "NSD2", "NSMCE2", "NSUN2", "NUP107", "NUP188", "NUP37", "NUP93", "OGT", "OPA1", "OSGEP", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PARN", "PCBD1", "PDCD6", "PDE6D", "PDHB", "PDHX", "PEX19", "PGM3", "PHF6", "PHF8", "PHIP", "PI4KA", "PIGG", "PIGK", "PISD", "PITRM1", "PLAA", "PNP", "POFUT1", "POLD1", "POLE", "PON2", "POR", "PPIL1", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PQBP1", "PRCC", "PREPL", "PRKAR1A", "PRPF31", "PRPF4", "PSAP", "PSMB4", "PTDSS1", "PTPRF", "PTRH2", "PUF60", "PURA", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAD21", "RAD50", "RALA", "RANGRF", "RAPGEF2", "RARS", "RBM10", "RBM8A", "RBMX", "RBPJ", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RMND1", "RNASEH2A", "RPL31", "RPL35", "RPS10", "RPS14", "RPS19", "RTN2", "SBDS", "SC5D", "SCYL2", "SDHA", "SDHB", "SEC31A", "SEC63", "SEPT9", "SERPINH1", "SET", "SF3B1", "SHOC2", "SIGMAR1", "SKIV2L", "SLC16A1", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC39A14", "SMARCA4", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SOAT1", "SPART", "SPECC1L", "SPEN", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC2", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUFU", "TAF15", "TAP2", "TBCD", "TBCE", "TCOF1", "TELO2", "TFG", "TIA1", "TIMMDC1", "TJP2", "TMEM126B", "TMEM165", "TMEM199", "TMTC3", "TNPO3", "TPM1", "TPM3", "TPP2", "TRAPPC4", "TTC19", "TTC37", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "UBA5", "UGDH", "UNC119", "UNC45A", "UROD", "USP7", "VAMP7", "VANGL1", "VIM", "VPS11", "VPS13D", "VPS33B", "VPS4A", "VPS51", "WASHC5", "WBP11", "WDR45B", "WFS1", "YARS", "ZC3H14", "ZMPSTE24", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_kegg/advanced/idx2term.json b/msigdb_kegg/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/msigdb_kegg/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/msigdb_kegg/basic/idx2term.json b/msigdb_kegg/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fa506879df91466ec8607da25e2105ad2c5a30e8 --- /dev/null +++ b/msigdb_kegg/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Hypertrophic 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score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..55dc96e8534d336c40746a56ce4707993b7fe78e --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 179, + "title": "Average number of proteins per term", + "value": 15.653631284916202 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e2898aafeb095ba8ef96949f079d87ad550c22a0 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6903141ec1207e4186c59b5a4cac159cf25e3ab8 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,70 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Type ii diabetes mellitus 0.713430561790167 1.7934565594899197 0.072899950756097 0.9999986948448486 0.9320779418100976 9 O00330 1 +Ascorbate and aldarate metabolism 0.6856391726933314 1.6466488741773644 0.0996302384608216 0.9999999930602906 1.0 6 P30837,P49419 2 +Histidine metabolism 0.6765846839983491 1.6049915883377026 0.1084956558494805 0.9999999988194076 1.0 6 P30837 1 +B cell receptor signaling pathway 0.639838116122746 1.450511168976581 0.1469160268794247 0.9999999999995558 1.0 10 P62993,O14920,P31751 3 +Gap junction 0.6348048908063142 1.4444670236386763 0.1486076492706618 0.9999999999996888 1.0 12 P62993,P04350,Q13509 3 +Acute myeloid leukemia 0.6232236517363824 1.3639685172459135 0.1725774744574351 0.999999999999998 1.0 9 O14920,P31751 2 +Allograft rejection 0.6991803353731629 1.35907398684734 0.1741231449254834 0.9999999999999988 1.0 4 P01889,P04439 2 +Graft versus host disease 0.6991803353731629 1.35907398684734 0.1741231449254834 0.9999999999999988 1.0 4 P01889,P04439 2 +Autoimmune thyroid disease 0.6991803353731629 1.35907398684734 0.1741231449254834 0.9999999999999988 1.0 4 P01889,P04439 2 +Small cell lung cancer 0.6170725739866361 1.334319843640598 0.1820990569726035 0.9999999999999998 1.0 9 O14920,P31751,Q05397 3 +Dilated cardiomyopathy 0.6132741577956723 1.3108554064274631 0.1899066192484775 1.0 1.0 7 P05556,P50402,P02545,P09493 4 +Limonene and pinene degradation 0.5982037868319492 1.2396255766564457 0.2151139159704196 1.0 1.0 7 P30837 1 +Rig i like receptor signaling pathway 0.593267923968875 1.217165310675262 0.223541325672214 1.0 1.0 6 O14920 1 +Viral myocarditis 0.5784966326402164 1.1563665638690117 0.2475312520207069 1.0 1.0 11 P01889,Q7Z406,O43432,P04439 4 +Hypertrophic cardiomyopathy hcm 0.5761499148211273 1.136716745591871 0.2556567166767798 1.0 1.0 9 P05556,P09493,P02545,P54646,P16615,P54619,P50402,P06753 8 +Type i diabetes mellitus 0.6192207211569222 1.1210304990111366 0.2622748803913723 1.0 1.0 5 P01889,P04439 2 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.6051653711820808 1.0606824864708972 0.2888342217411779 1.0 1.0 5 Q92643 1 +Jak stat signaling pathway 0.55868132539863 1.0528842146473778 0.2923940616212164 1.0 1.0 7 P62993,P31751,Q92783 3 +Apoptosis 0.5462628905175436 1.0278158042006198 0.3040364806039193 1.0 1.0 15 O14920,O95831 2 +Glycerolipid metabolism 0.5463346254597758 0.9978385248495818 0.3183576657595206 1.0 1.0 11 P30837,Q6UWP7 2 +Beta alanine metabolism 0.5311451026144143 0.9212050444203496 0.3569433851216295 1.0 1.0 10 P30837,P49419 2 +Nod like receptor signaling pathway 0.5273040621427834 0.9027072464596534 0.3666812894928757 1.0 1.0 10 O14920 1 +Arginine and proline metabolism 0.4966026708833581 0.8771143521113643 0.3804245299751074 1.0 1.0 22 P30837,P49419,P13674,Q96QD8 4 +Homologous recombination 0.5124654967415041 0.8319634230497983 0.4054295906835774 1.0 1.0 9 P35244,P15927,Q92878,O60934,P49959,Q04837 6 +Notch signaling pathway 0.5085186929859061 0.8133964872572004 0.4159907726845961 1.0 1.0 9 Q13547,Q92542,O14641 3 +Prostate cancer 0.4997481801989647 0.7895237933524407 0.4298059289177891 1.0 1.0 15 P24941,O14920,P31751 3 +N glycan biosynthesis 0.4948530668317681 0.7583086935534061 0.4482662040710368 1.0 1.0 14 Q8TCJ2,Q96AA3,Q13724 3 +Toll like receptor signaling pathway 0.4954475791617559 0.7530566849586853 0.4514158517034294 1.0 1.0 12 O14920 1 +Tryptophan metabolism 0.4823920511335176 0.6970807082456489 0.485752286565448 1.0 1.0 14 P30837,P35610,P49419 3 +Chemokine signaling pathway 0.4671829302581134 0.6771554450831031 0.4983073333851635 1.0 1.0 20 P42224,O14920,P61586,P41240,P62993,P31751,Q05397 7 +Steroid biosynthesis 0.4795193161216478 0.6763098408851249 0.4988439460261138 1.0 1.0 11 Q15800,Q15392,Q16850,Q14534,P48449,P35610 6 +O glycan biosynthesis 0.5284648284875141 0.666267265920943 0.5052402846057609 1.0 1.0 4 Q10471,Q10472 2 +Parkinsons disease 0.3224710516218998 0.6564447995563806 0.5115379735556695 1.0 1.0 54 P00403,P03886,O96000,P00846 4 +Fatty acid metabolism 0.4069552899719046 0.5361964737378697 0.591822770335866 1.0 1.0 29 P23786,P11310,P30837,P35610,P49419 5 +Pancreatic cancer 0.4431146450052696 0.5097961287212824 0.6101942981260031 1.0 1.0 13 O14920 1 +Oxidative phosphorylation 0.315299343989919 0.5083604624747718 0.6112005749964613 1.0 1.0 60 P00403,P03886,O96000,P00846 4 +Peroxisome 0.3976992171237726 0.4804068738114467 0.6309381075400595 1.0 1.0 29 Q9BY49,P48735 2 +Fc epsilon ri signaling pathway 0.4287896752261229 0.4573029403541453 0.6474533165736198 1.0 1.0 9 P31751 1 +Lysine degradation 0.4236649373672648 0.4451651995505912 0.6562003739050228 1.0 1.0 19 P30837,P35610,P49419 3 +Ecm receptor interaction 0.4563673054504706 0.4105594218378404 0.6813956232810661 1.0 1.0 4 O75330,Q08722 2 +Mismatch repair 0.4148257274244373 0.3923435511322704 0.6948043887523316 1.0 1.0 17 Q9UQ84,P15927 2 +T cell receptor signaling pathway 0.4127120163162462 0.3875346537879023 0.6983604352521096 1.0 1.0 18 P62993,O14920,P31751 3 +Antigen processing and presentation 0.4061702576467334 0.3582640648191805 0.720145707781672 1.0 1.0 18 P04439,Q9UL46,P01889,P27824,P27797,P0DMV9,P54652,P11142,P10321,P16220,P61289 11 +Adipocytokine signaling pathway 0.402950648299862 0.3370281101016127 0.7360957096996625 1.0 1.0 15 O14920 1 +Chronic myeloid leukemia 0.401715959787687 0.3329047133300044 0.7392062114656748 1.0 1.0 16 P62993,O14920,P31751 3 +Cell adhesion molecules cams 0.3937149052027769 0.3261815805529125 0.7442869765563682 1.0 1.0 8 P10586,P04439 2 +Butanoate metabolism 0.3955842577819357 0.3123365819655444 0.7547847412556696 1.0 1.0 18 P35610,P30837,Q16836,P49419 4 +Snare interactions in vesicular transport 0.378424195485008 0.2533777758611298 0.7999762997352629 1.0 1.0 11 O15400 1 +Hedgehog signaling pathway 0.3993197278911521 0.245687094070234 0.8059244634783564 1.0 1.0 4 Q9ULC3,Q9UMX1,P48729 3 +Dna replication 0.3590617921309785 0.2294975931312803 0.8184821911163382 1.0 1.0 27 P35250,P15927,Q9NRF9,Q14566,P33991,P51530,Q07864 7 +Alpha linolenic acid metabolism 0.6295037389530853 0.2020654320907106 0.8398655716044512 1.0 1.0 2 Q15067 1 +Non small cell lung cancer 0.359674994544925 0.1966691836689979 0.844086426949682 1.0 1.0 10 P62993,Q13043,P31751 3 +Mtor signaling pathway 0.3630028706899944 0.1963896557299464 0.8443051921448059 1.0 1.0 12 P31751 1 +Pathways in cancer 0.2711535942556173 0.180171914508335 0.8570176065731883 1.0 1.0 55 P05556,P24941,Q13547,P62993,P42224,Q92734,O14920,Q16204,Q13043,P61586,O14641,P25054,P11233,P12270,Q05397,P31751,P42771,P35221 18 +Alzheimers disease 0.2697722529706521 0.139493672487049 0.889060055681258 1.0 1.0 58 P00403,O96000,P00846 3 +Non homologous end joining 0.3264719060619 0.134472965931952 0.893028586969667 1.0 1.0 6 Q92878,P12956 2 +Adherens junction 0.3456430021566448 0.1305162760786467 0.8961579778362005 1.0 1.0 22 Q9UQB8 1 +Nucleotide excision repair 0.3432513233183465 0.1171543297028089 0.9067377572347636 1.0 1.0 18 P35244,P35250,P15927,Q9NRF9,P18074,Q07864 6 +Cardiac muscle contraction 0.3366316841377753 0.0992190589366699 0.9209643426814892 1.0 1.0 22 P00403,P05026 2 +Porphyrin and chlorophyll metabolism 0.3308660155900607 0.092329591722707 0.9264361779843312 1.0 1.0 14 Q7KZN9,P30519 2 +Vegf signaling pathway 0.3257560054308094 0.0893373579075679 0.9288138054352786 1.0 1.0 12 P31751 1 +Progesterone mediated oocyte maturation 0.3295928888134901 0.0823705920629327 0.9343520206957148 1.0 1.0 24 P24941,P31751,Q13257 3 +Basal cell carcinoma 0.2961481588255207 0.0604515699689035 0.9517959868278404 1.0 1.0 7 O14641 1 +Endometrial cancer 0.3118696095191908 0.057142156988772 0.9544319548445022 1.0 1.0 12 P62993,P31751 2 +Natural killer cell mediated cytotoxicity 0.3152492643108202 0.0539124149659525 0.9570049453397698 1.0 1.0 14 P62993,P01889,P04439 3 +Epithelial cell signaling in helicobacter pylori infection 0.3190956647628161 0.0444313382805811 0.9645605819715948 1.0 1.0 21 O14920,P36543,P21281,Q93050 4 +Tight junction 0.2929925979182816 0.0270202739026068 0.9784435636981424 1.0 1.0 33 P63151,P55196,Q9UDY2,Q16625,Q14247,P08754,P61586,Q13813,Q92797,P35221,P30154,Q7Z406,P20337,P31751,Q15334 15 +Fc gamma r mediated phagocytosis 0.307272766640311 0.0173876919412634 0.986127328080642 1.0 1.0 19 P49006 1 +Tgf beta signaling pathway 0.2727569838191953 0.0018947777558823 0.998488186987043 1.0 1.0 10 P30154,P61586,O75116 3 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d7e01fb286f7a762f508c72cd65a7011c4cf37e5 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "APRT", "AQR", "ARFGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCL10", "BIRC6", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CASP3", "CBL", "CBR1", "CCDC6", "CCNB1", "CD47", "CDC16", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDKN2A", "CFL1", "CFL2", "CHD8", "CHEK2", "CHERP", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHST14", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CREB1", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBT", "DCK", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNM1L", "DNM2", "DNMT1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTX3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENDOD1", "ENO1", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERBIN", "ERCC2", "ERO1A", "ESPL1", "EXO1", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAH", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA2", "GGCT", "GGH", "GLA", "GLB1", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNAI3", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAA1", "GPD2", "GPI", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IKBKB", "ILK", "IMPDH2", "IQGAP1", "IQGAP2", "IRS4", "ISYNA1", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KDELR1", "KDELR3", "L2HGDH", "LAMC1", "LAMP1", "LAP3", "LARS", "LARS2", "LCLAT1", "LDHA", "LDHB", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LYPLA1", "LYPLA2", "MAD2L1", "MAN1A1", "MAN2B1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPI", "MPST", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVK", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEFM", "NF1", "NIT2", "NLN", "NME1", "NME2", "NNT", "NPC1", "NPC2", "NSD2", "NSDHL", "NSF", "NT5C2", "NUDT12", "NUDT5", "NUDT9", "OAT", "OCLN", "OCRL", "OGDH", "ORC2", "ORC3", "ORC6", "OXA1L", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PECR", "PEX14", "PEX19", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHF5A", "PHGDH", "PI4KA", "PI4KB", "PIGG", "PIGK", "PIGT", "PIGU", "PIK3C3", "PIK3R4", "PIN1", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLRG1", "PMAIP1", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLD1", "POLDIP2", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "PPA1", "PPA2", "PPAT", "PPID", "PPIH", "PPIL1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP5C", "PPT1", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTDSS1", "PTGES2", "PTK2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QPRT", "RAB13", "RAB23", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RABEP1", "RAC1", "RAD21", "RAD23B", "RAD50", "RALA", "RAPGEF2", "RARS", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RIPK1", "RNASEH2A", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRM1", "RRM2", "RSL24D1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", 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a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..989d30ccfa2f5305f5d7b6a1314e95cdfb502f44 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..920d45372ab7ac58cd1828cab31fc0ba3931bf25 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,426 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Synthesis of pa 0.829282147947843 2.30883129274155 0.0209529448248875 0.9999999999997428 1.0 8 Q8NAN2,Q6UWP7,Q9NPH0 3 +Regulation of tp53 activity 0.4558468948941077 2.1664601359548548 0.0302760429238944 1.0 1.0 44 Q13547,P24941,P35250,Q13526,P15927,Q92878,Q96KQ7,O60934,Q8WXI9,Q9UQ84,Q92804,P51530,P31751 13 +Activation of ampk downstream of nmdars 0.7836767020415731 2.088299207754584 0.0367708528870973 1.0 1.0 6 P04350,Q13509 2 +Carboxyterminal post translational modifications of tubulin 0.8442453300949719 2.0737503221822258 0.0381025050291783 1.0 1.0 5 P04350,Q13509 2 +Downregulation of erbb2 signaling 0.765873773087853 2.0094888161589664 0.044485319569022 1.0 1.0 6 P31751 1 +Transport of connexons to the plasma membrane 0.8503278651451999 1.976465818611706 0.0481020433966334 1.0 1.0 4 P04350,Q13509 2 +Gap junction assembly 0.8503278651451999 1.976465818611706 0.0481020433966334 1.0 1.0 4 P04350,Q13509 2 +Regulation of beta cell development 0.8453946140667391 1.9567547985904463 0.0503763037625772 1.0 1.0 4 O00330 1 +Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.8145550344878556 1.9517355372445784 0.0509696111223467 1.0 1.0 5 O60934,Q9UQ84,P51530 3 +Resolution of d loop structures 0.8145550344878556 1.9517355372445784 0.0509696111223467 1.0 1.0 5 O60934,Q9UQ84,P51530 3 +Diseases of dna repair 0.74537137818799 1.9321773000640177 0.0533376259663984 1.0 1.0 8 O60934,Q9UQ84,P51530 3 +Small interfering rna sirna biogenesis 0.8268474961102973 1.8823335664727192 0.0597907397353023 1.0 1.0 4 Q9UPY3 1 +Endosomal vacuolar pathway 0.8187074829932031 1.849518161771563 0.0643830277731551 1.0 1.0 4 P01889,P04439,Q9UIQ6 3 +Recruitment of numa to mitotic centrosomes 0.5967491954497177 1.8399491917882271 0.0657756970047698 1.0 1.0 30 Q9BSJ2,O95684,P04350,Q13509,O43805,Q7Z460,Q9H6D7,Q9BUF5,O75935 9 +Constitutive signaling by overexpressed erbb2 0.8121595445715456 1.823055341564545 0.0682950094670471 1.0 1.0 4 Q96RT1 1 +Regulation of innate immune responses to cytosolic dna 0.9036536866283736 1.8098970799152525 0.0703117490675668 1.0 1.0 3 P19474 1 +Glucuronidation 0.8900754959435302 1.7583218589787095 0.0786927604228786 1.0 1.0 3 Q9NUJ1 1 +Signaling by erbb2 in cancer 0.7654420290300724 1.7467932955314518 0.0806731999861509 1.0 1.0 5 Q96RT1 1 +Signaling by erbb2 ecd mutants 0.7654420290300724 1.7467932955314518 0.0806731999861509 1.0 1.0 5 Q96RT1 1 +Copi independent golgi to er retrograde traffic 0.6398155430047837 1.741258838885832 0.0816382177070143 1.0 1.0 23 Q9H2M9,P04350,Q13509,Q10472,Q8TD16,Q9NP72,Q9BUF5,Q15042,Q15102,O75935 10 +Signaling by flt3 fusion proteins 0.8663719823189412 1.6678686725418286 0.0953417997766554 1.0 1.0 3 P62993,Q14789 2 +Collagen formation 0.6794216870345989 1.6523541557885202 0.0984623753223523 1.0 1.0 11 P13674,Q32P28,Q03001 3 +Ncam signaling for neurite out growth 0.6816831788268287 1.6367989646758143 0.1016724821561299 1.0 1.0 8 Q01082,O15020,P62993,P16220,Q05397 5 +Signaling by notch3 0.6804701828859528 1.6260989730744568 0.1039286024668735 1.0 1.0 7 P42224,Q92542,Q13573,P67809 4 +Sensing of dna double strand breaks 0.7621427408035618 1.619145725031929 0.1054159125686751 1.0 1.0 4 P52292,O60934 2 +Signaling by pdgfr in disease 0.7265392516510354 1.582017804744919 0.1136455059600485 1.0 1.0 5 P62993,P42224,Q6UN15 3 +Fgfr1 mutant receptor activation 0.6706869347204655 1.5805515710004974 0.1139806064521016 1.0 1.0 7 P62993,O95684,O95429 3 +Transport of bile salts and organic acids metal ions and amine compounds 0.7517006802721107 1.576225520177411 0.1149738391397656 1.0 1.0 4 P53985,Q8TAD4,Q15043 3 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.6648671682221796 1.55090076456364 0.1209254671802204 1.0 1.0 6 P31751 1 +E3 ubiquitin ligases ubiquitinate target proteins 0.6382871990424799 1.5245181724911838 0.1273793208212743 1.0 1.0 16 O95999,O75150,Q5VTR2,Q9BUN8,P04439 5 +Transcriptional regulation of granulopoiesis 0.654224803398833 1.5128594740588142 0.1303153578517228 1.0 1.0 9 P24941,Q13951,Q03164 3 +Sting mediated induction of host immune responses 0.6549124376045519 1.5047985285270569 0.1323758821976586 1.0 1.0 6 P19474 1 +Signaling by fgfr1 in disease 0.6530037508314092 1.501550270607608 0.1332132946051465 1.0 1.0 8 P62993,O95684,O95429 3 +Homologous dna pairing and strand exchange 0.6454288298923714 1.4972534409187694 0.1343273246530785 1.0 1.0 12 P35250,P15927,O60934,Q9UQ84,P51530 5 +Hdr through single strand annealing ssa 0.6454288298923714 1.4972534409187694 0.1343273246530785 1.0 1.0 12 P35250,P15927,O60934,Q9UQ84,P51530 5 +Collagen biosynthesis and modifying enzymes 0.6487323593007719 1.4865589326697597 0.1371313410466745 1.0 1.0 9 P13674,Q32P28 2 +Amino acid transport across the plasma membrane 0.6987129695698466 1.4630922259906762 0.1434421447878178 1.0 1.0 5 P08195,Q96QD8 2 +Potential therapeutics for sars 0.4929031351011272 1.460605332905564 0.1441237819300518 1.0 1.0 35 Q99720,P05026 2 +Interaction between l1 and ankyrins 0.7213282219466067 1.4508556888673696 0.1468200488529607 1.0 1.0 4 Q01082,O15020 2 +Signaling by erbb4 0.6918929095168826 1.433837654560676 0.1516185967307017 1.0 1.0 5 P62993,Q92542,Q15334 3 +Signal regulatory protein family interactions 0.7124107178013421 1.4139281086416715 0.157383011863371 1.0 1.0 4 Q08722,Q05397 2 +Recruitment of mitotic centrosome proteins and complexes 0.5536774044183824 1.3934107707195125 0.1634956105437637 1.0 1.0 27 Q9BSJ2,O95684,P04350,O43805,Q7Z460,Q9H6D7,O75935 7 +Striated muscle contraction 0.682189814921809 1.3921587148760284 0.1638743415446719 1.0 1.0 5 P09493 1 +Binding and uptake of ligands by scavenger receptors 0.6296298050682747 1.38802017644647 0.1651309013434536 1.0 1.0 7 Q8WTV0 1 +Notch3 activation and transmission of signal to the nucleus 0.7925954238560594 1.3838147446998017 0.1664151870390262 1.0 1.0 3 P67809 1 +Mecp2 regulates transcription of neuronal ligands 0.7900577261507349 1.3740039276801828 0.1694404630726884 1.0 1.0 3 Q13547 1 +Post chaperonin tubulin folding pathway 0.6252525439320991 1.373741705034828 0.1695218845694772 1.0 1.0 9 P04350,Q13509 2 +Aurka activation by tpx2 0.5504287406781911 1.3727529711721118 0.1698291554654127 1.0 1.0 27 O95684,P04350,O43805 3 +Integrin signaling 0.6723516205645249 1.349842402676811 0.1770665402187494 1.0 1.0 5 P62993,Q05397 2 +Platelet aggregation plug formation 0.6723516205645249 1.349842402676811 0.1770665402187494 1.0 1.0 5 P62993,Q05397 2 +Pkmts methylate histone lysines 0.6184084083718854 1.3462295599325262 0.1782284947345096 1.0 1.0 10 Q9H7B4 1 +Grb2 sos provides linkage to mapk signaling for integrins 0.7828052053430714 1.3459613907390475 0.1783149684270926 1.0 1.0 3 Q05397 1 +Sealing of the nuclear envelope ne by escrt iii 0.6167063941139627 1.34514371813919 0.1785788274201811 1.0 1.0 11 P53990,Q8NC56,Q8WUX9,P04350,Q13509,Q9Y3E7,Q9BUF5,Q9UN37 8 +Signaling by cytosolic fgfr1 fusion mutants 0.6662727763829854 1.32367358476685 0.1856114749534581 1.0 1.0 5 P62993,O95684 2 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.6601917740090355 1.29748295353307 0.1944650666396312 1.0 1.0 5 P01889,P10321,P04439 3 +Synaptic adhesion like molecules 0.6591837447667375 1.2931404801059567 0.1959624768026842 1.0 1.0 5 P10586 1 +Signaling by hippo 0.6063317137280386 1.2794266328215211 0.2007468602024209 1.0 1.0 8 O14641,Q4VCS5,Q9UDY2 3 +Signaling by fgfr in disease 0.5880787489462118 1.2784209633515276 0.2011010363464924 1.0 1.0 17 P35269,O95684,P13984,Q09161,P62875,P52434,O95429,P62993,P19388 9 +Inlb mediated entry of listeria monocytogenes into host cell 0.6039675433329375 1.267254949641917 0.2050641433392184 1.0 1.0 6 O14964,P62993 2 +Rhobtb gtpase cycle 0.51109587964258 1.2636902364011424 0.2063412308935346 1.0 1.0 30 Q96T58,O43396,P38159,Q8WWQ0,P08670,Q5VTR2,P62995,Q9BT78 8 +Nuclear envelope ne reassembly 0.373271570748326 1.2484257199870343 0.2118751949133659 1.0 1.0 49 Q9Y2U8,Q96EE3,P20700,P02545,P50402,P63151,Q8N1F7,Q8NFH4,Q9BUF5,Q9UN37,Q8NC56,Q8WUX9,Q5SRE5,Q9Y3E7,P53990,Q8NFH5,Q86Y07,P04350,Q13509,P42166,Q9BVL2 21 +Nef mediated downregulation of mhc class i complex cell surface expression 0.6719976659292034 1.2462592936624162 0.212669217037777 1.0 1.0 4 P04439,Q10567 2 +Signaling by retinoic acid 0.5977875549209803 1.2455783953148198 0.2129192180083612 1.0 1.0 10 O94788 1 +Dap12 interactions 0.6432515019928877 1.2244907256988502 0.2207671628092105 1.0 1.0 5 P62993,P01889 2 +Runx3 regulates p14 arf 0.7511050663039796 1.2234360176242616 0.2211650564772764 1.0 1.0 3 Q13951,P25440 2 +Hdr through homologous recombination hrr 0.5734582289800721 1.219170641491433 0.2227794324319805 1.0 1.0 18 P35250,P15927,Q92878,O60934,Q9UQ84,Q9NRF9,P51530,Q07864 8 +Regulation of gene expression in beta cells 0.9687287559483316 1.206895526731572 0.2274723806286556 1.0 1.0 2 O00330 1 +Formation of the early elongation complex 0.5821141420325101 1.201120003806134 0.229704654468368 1.0 1.0 14 P35269,Q8IXH7,P13984,Q09161,P62875,P52434,O00267,P18074 8 +Rhobtb3 atpase cycle 0.6608843537415041 1.2001563352890128 0.2300786298725086 1.0 1.0 4 O14964,O60664,P51151 3 +Signaling by nuclear receptors 0.3765003386712944 1.1919005343059443 0.2333002486661783 1.0 1.0 55 P50416,P35269,P13984,O94788,O43815,O00330,P52292,O60216,Q13951,Q8NB78,Q9UQE7,P62875,P16220,P19388,P31751,Q13547,P11177,P52434,Q13451,O00767,Q8WVM7,Q05397 22 +Notch3 intracellular domain regulates transcription 0.6587893079656086 1.1914701318453549 0.2334690753095993 1.0 1.0 4 P42224,Q13573 2 +Hiv transcription initiation 0.5851780756606644 1.1839745984002477 0.2364231181984875 1.0 1.0 10 P35269,P13984,P62875,Q92804,P52434,P18074 6 +Gap junction trafficking and regulation 0.5837813297721506 1.177151283142016 0.2391351292485408 1.0 1.0 10 P04350,Q13509 2 +Transport of inorganic cations anions and amino acids oligopeptides 0.5826164936410415 1.1714611906624384 0.2414134487048658 1.0 1.0 10 Q96QD8 1 +Meiotic recombination 0.5825060178647891 1.1709215455842508 0.241630313848475 1.0 1.0 10 Q92878,P24941,O60934,P15927 4 +Meiosis 0.5472987733190977 1.1694026044957784 0.2422414609959056 1.0 1.0 22 P35244,P24941,P15927,Q92878,Q9UH99,O60934,Q9UQE7,P54652,O94901,P49959,O60216,P02545,Q8WVM7 13 +Reproduction 0.5472987733190977 1.1694026044957784 0.2422414609959056 1.0 1.0 22 P35244,P24941,P15927,Q92878,Q9UH99,O60934,Q9UQE7,P54652,O94901,P49959,O60216,P02545,Q8WVM7 13 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.732403944236665 1.151329346101989 0.2495967685809668 1.0 1.0 3 P16220,P52292 2 +Carnitine metabolism 0.5782113836906176 1.1466748108606362 0.251516044737651 1.0 1.0 6 O43772 1 +Signaling by erbb2 0.5755997082213269 1.142053827288232 0.2534316461988912 1.0 1.0 11 P62993,P31751,Q96RT1 3 +Negative regulation of met activity 0.5774700723805495 1.1415813347359058 0.253628086179128 1.0 1.0 7 O14964,P62993 2 +Response to elevated platelet cytosolic ca2 0.5124557031526864 1.130740467560452 0.2581643433735858 1.0 1.0 27 Q9BWS9,Q9NUQ9,P07602,P10909,O43852 5 +Depolymerisation of the nuclear lamina 0.5738783436743343 1.1257519126101698 0.2602705435850132 1.0 1.0 9 Q8NC56,P02545,Q9Y2U8,P42166,P50402 5 +Rhobtb1 gtpase cycle 0.546953136813564 1.1160746089785414 0.2643901996929956 1.0 1.0 20 Q96T58,O43396,P38159,P08670,Q5VTR2,P62995,Q9BT78 7 +Integrin cell surface interactions 0.7177830669840335 1.0951405800072749 0.2734550528602593 1.0 1.0 3 Q08722,P35613 2 +G0 and early g1 0.6121024516834483 1.0904453624098902 0.2755170088563776 1.0 1.0 5 P24941 1 +N glycan trimming in the er and calnexin calreticulin cycle 0.5570155796332614 1.0835714296032164 0.2785548641828941 1.0 1.0 15 Q86TM6,Q9BUN8,Q13724 3 +Cytosolic iron sulfur cluster assembly 0.609871481038057 1.0808684090263605 0.2797556528967724 1.0 1.0 5 P28340,P18074 2 +Rnd3 gtpase cycle 0.5473436517116974 1.0773723137726208 0.2813139678166063 1.0 1.0 18 O43396,P38159,Q9Y2U8,Q03001,Q9UJF2,Q07065 6 +Basigin interactions 0.5633872550163876 1.077354488276326 0.2813219282425343 1.0 1.0 6 P08195,P53985,P35613,P05026 4 +Abortive elongation of hiv 1 transcript in the absence of tat 0.5563187496480054 1.059682088348593 0.28928925419037 1.0 1.0 13 P35269,Q8IXH7,P13984,Q09161,P62875,P52434,O00267 7 +Interferon alpha beta signaling 0.559438876332712 1.0555119351502182 0.2911912538533898 1.0 1.0 8 P01889,P10321,P04439 3 +Listeria monocytogenes entry into host cells 0.5586972238396799 1.0519799817554685 0.292808734075316 1.0 1.0 8 O14964,P62993,Q92783 3 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.5556261929616053 1.0411309488131366 0.2978147776122484 1.0 1.0 6 P62993,P31751 2 +Mrna capping 0.5538996977030846 1.0403503636401752 0.2981771534694895 1.0 1.0 12 P35269,P13984,Q09161,P62875,P52434,O00267,P18074 7 +Signaling by fgfr2 in disease 0.5537495448056179 1.0342873617368755 0.301001843382795 1.0 1.0 11 P35269,P13984,Q09161,P62875,P52434,P62993 6 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5445879189320068 1.0314264279073229 0.3023408929350162 1.0 1.0 16 P04350,O15212,Q9UHV9,Q13509,P78371 5 +Nod1 2 signaling pathway 0.5949274035496703 1.0168578918118747 0.3092210373269657 1.0 1.0 5 O14920,Q13685 2 +Heme degradation 0.6158758310980644 1.0143251479230897 0.3104276281051845 1.0 1.0 4 P30519 1 +Runx1 regulates expression of components of tight junctions 0.6944960056797003 1.0061606916824797 0.3143382775313952 1.0 1.0 3 Q13951 1 +Regulation of tp53 activity through phosphorylation 0.4926068960842978 1.0044880107657308 0.3151434472458594 1.0 1.0 27 P24941,P35250,Q13526,P15927,O60934,Q9UQ84,Q92804,P51530 8 +Translation of sars cov 1 structural proteins 0.5480240058373207 1.0027273172116338 0.3159924458582601 1.0 1.0 7 Q13724 1 +Mastl facilitates mitotic progression 0.5878011296769022 0.986440121754112 0.3239171848521387 1.0 1.0 5 O43768 1 +Interleukin 2 family signaling 0.687510001472827 0.9796281196588018 0.3272697193002076 1.0 1.0 3 P62993 1 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.687510001472827 0.9796281196588018 0.3272697193002076 1.0 1.0 3 P62993 1 +Flt3 signaling in disease 0.5858884662885951 0.9782901659947648 0.3279308322827339 1.0 1.0 5 P62993,Q14789 2 +Regulation of pyruvate dehydrogenase pdh complex 0.5419661767632638 0.9742904908081004 0.3299123248210081 1.0 1.0 7 O00330 1 +Assembly and cell surface presentation of nmda receptors 0.5420786580066184 0.9727545524804562 0.3306753052293183 1.0 1.0 9 P04350,Q13509,Q15334 3 +Irs mediated signalling 0.5821050815474185 0.9621881498688069 0.3359551006158405 1.0 1.0 5 P62993,P31751 2 +Transcription of the hiv genome 0.5108116080273727 0.9584947475902216 0.3378133387777722 1.0 1.0 22 P23193,P35269,Q8IXH7,P13984,Q09161,P62875,Q92804,P52434,O00267,P18074,Q14241 11 +Signaling by notch2 0.6818214389273064 0.9580894156401768 0.3380176722140524 1.0 1.0 3 Q92542 1 +Insulin processing 0.5347442907709261 0.940475592314715 0.3469736636552671 1.0 1.0 7 Q8TAD4,Q9NV70,P33176 3 +Syndecan interactions 0.5976190476190478 0.9397405184021238 0.3473506760719371 1.0 1.0 4 P05556,Q9Y296,P12814 3 +Fgfr2 mutant receptor activation 0.5337182307981072 0.9327835634818246 0.3509317293216671 1.0 1.0 9 P35269,P13984,Q09161,P62875,P52434 5 +Signaling by fgfr2 iiia tm 0.5337182307981072 0.9327835634818246 0.3509317293216671 1.0 1.0 9 P35269,P13984,Q09161,P62875,P52434 5 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.525708175040172 0.93259038739531 0.3510314983989451 1.0 1.0 16 Q07065,Q15293,Q5JRA6,O43852 4 +Formation of fibrin clot clotting cascade 0.8895309313392101 0.9274589413314503 0.3536883001874795 1.0 1.0 2 P42785 1 +Intrinsic pathway of fibrin clot formation 0.8895309313392101 0.9274589413314503 0.3536883001874795 1.0 1.0 2 P42785 1 +Signalling to ras 0.5937395115149602 0.9239811812510912 0.3554961138444306 1.0 1.0 4 P62993,P11233 2 +Mismatch repair 0.5304541854104634 0.9201108653510862 0.3575148269883001 1.0 1.0 11 Q9UQ84 1 +Lipophagy 0.5918367346938637 0.916264892507165 0.3595279769618862 1.0 1.0 4 P54646,P11142,O60664 3 +Ngf stimulated transcription 0.590816326530615 0.9121305393957018 0.3617000036133837 1.0 1.0 4 P16220,Q00535,Q14839 3 +Meiotic synapsis 0.5244908570563469 0.90672809598369 0.3645506019931177 1.0 1.0 14 Q9UH99,Q9UQE7,O60216,P20700,O94901,P54652,P02545,Q8WVM7 8 +Scavenging by class f receptors 0.5884353741496472 0.9024940016974852 0.3667945063792825 1.0 1.0 4 P07900,P27797,Q9Y4L1 3 +Regulation of tp53 activity through acetylation 0.525077621212673 0.8939263618536522 0.371361291982355 1.0 1.0 11 Q13526,P31751,Q8WXI9 3 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.5249546609918271 0.8922074414183053 0.372281754330297 1.0 1.0 8 O14920,P09601,Q13685 3 +Nephrin family interactions 0.5243685555249583 0.8920920932495078 0.3723435725509063 1.0 1.0 7 Q9Y5K6,Q01082 2 +Mitochondrial biogenesis 0.4181136743639568 0.8850037090631346 0.3761546309079835 1.0 1.0 35 Q13505,P00846,Q6UXV4,Q9NX63,Q16891,O75431,Q9NVH1,P48735,P16220 9 +Activation of the pre replicative complex 0.5048783985586242 0.8818057863612433 0.3778818420014409 1.0 1.0 20 P24941,Q13416,P15927,Q9Y619,Q9NRF9,Q14566,P33991,Q07864 8 +Adora2b mediated anti inflammatory cytokines production 0.5620292453590473 0.8772516943393931 0.3803499434811375 1.0 1.0 5 P08754,P16220,P10644 3 +Rnd1 gtpase cycle 0.5169783076317076 0.8770420486696964 0.380463799442003 1.0 1.0 15 O43396,P38159,Q9UJF2,Q03001 4 +Trna modification in the nucleus and cytosol 0.5192670675833706 0.8640853401898186 0.3875410115781241 1.0 1.0 9 Q96FX7 1 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.5161773510412304 0.8510699842221375 0.3947304779097027 1.0 1.0 8 P30154,O14641 2 +Anchoring of the basal body to the plasma membrane 0.4682782580991502 0.851062895662799 0.3947344153613672 1.0 1.0 27 O95684,P04350,O43805 3 +Fgfr2 alternative splicing 0.5094929452861648 0.8484217508617491 0.3962031335186491 1.0 1.0 16 P35269,P13984,Q09161,P62875,Q01085,P52434,P31483,P19388 8 +Cholesterol biosynthesis 0.5059937559349845 0.8415782746695406 0.4000240541490045 1.0 1.0 17 Q15800,Q15392,Q16850,Q14534,P48449 5 +Establishment of sister chromatid cohesion 0.5137118419981651 0.8395571764009206 0.4011567184067441 1.0 1.0 8 Q9UQE7,Q7Z5K2,Q8WVM7,Q29RF7 4 +Noncanonical activation of notch3 0.8630183548606232 0.8368434354889556 0.4026805786862835 1.0 1.0 2 P67809 1 +Hiv transcription elongation 0.4965230516277781 0.8358500709578776 0.4032392539532847 1.0 1.0 20 P23193,P35269,Q8IXH7,P13984,Q09161,P62875,P52434,O00267,P18074,Q14241 10 +Platelet calcium homeostasis 0.5671077025663647 0.8169014917248172 0.4139847252548598 1.0 1.0 4 P20020 1 +Reduction of cytosolic ca levels 0.5671077025663647 0.8169014917248172 0.4139847252548598 1.0 1.0 4 P20020 1 +Formation of tubulin folding intermediates by cct tric 0.5080747691522496 0.8141916808576538 0.4155351505378655 1.0 1.0 12 P04350,P78371,Q13509 3 +Esr mediated signaling 0.3447416274930268 0.8103136761648955 0.4177599170999406 1.0 1.0 42 Q13547,P35269,P52292,P13984,Q9UQE7,P62875,P52434,Q13951,Q13451,P16220,P19388,O43815,P31751,Q8WVM7,Q05397 15 +Flt3 signaling 0.5433217123498169 0.7990892645806006 0.4242386540812819 1.0 1.0 5 P62993,P31751 2 +Runx2 regulates genes involved in cell migration 0.8497620666213297 0.7923312830723457 0.4281675355874728 1.0 1.0 2 P31751 1 +Cdc6 association with the orc origin complex 0.5588926103955852 0.7843383897690228 0.4328415790851074 1.0 1.0 4 Q9Y619 1 +Regulation of plk1 activity at g2 m transition 0.4389628984564546 0.7763250884110127 0.4375570633599102 1.0 1.0 30 O95684,P04350,O43805 3 +Glycerophospholipid biosynthesis 0.4660856492750076 0.7754080236800145 0.4380985954015766 1.0 1.0 25 Q8NAN2,Q8N2A8,Q6UWP7,Q9NPH0,Q9BZF1 5 +Egfr downregulation 0.4975919123255148 0.7687062481151484 0.4420677149022833 1.0 1.0 7 O14964,P62993,Q92783 3 +Protein ubiquitination 0.4687186486879133 0.7645067422743111 0.4445653203365241 1.0 1.0 24 O95999,O75150,Q9BUN8,Q5VTR2,P04439 5 +Rna polymerase ii transcribes snrna genes 0.4759027072985822 0.759981993593412 0.447265348184958 1.0 1.0 22 Q8N201,Q5VT52,P35269,Q5TA45,P13984,Q09161,P62875,P52434,O00267 9 +Budding and maturation of hiv virion 0.497171869686061 0.7595384384294486 0.4475305292954104 1.0 1.0 11 Q9NP79,Q8WUX9,Q9NZZ3,Q9Y3E7,Q9UN37,O75351 6 +Rhobtb2 gtpase cycle 0.4819529547891013 0.7564435640533158 0.4493832970684599 1.0 1.0 20 O43396,P62995,P38159,Q8WWQ0 4 +Interleukin 35 signalling 0.6266575994559769 0.7534775263699465 0.451163011155349 1.0 1.0 3 P42224,P40763 2 +Interleukin 27 signaling 0.6266575994559769 0.7534775263699465 0.451163011155349 1.0 1.0 3 P42224,P40763 2 +Diseases associated with n glycosylation of proteins 0.4913465329427857 0.7457821029442198 0.4557990528949993 1.0 1.0 6 Q96AA3 1 +Chromatin modifying enzymes 0.3326636393958133 0.7441632199977906 0.4567777362144745 1.0 1.0 55 Q9UBU8,Q9H7B4,Q03164 3 +Ire1alpha activates chaperones 0.45932545664384 0.7353519144255856 0.462125198849725 1.0 1.0 25 Q86TM6,P43307,Q9Y4L1,P08240,P35611,Q9NWM8 6 +Ddx58 ifih1 mediated induction of interferon alpha beta 0.4883982080855104 0.7181436662287467 0.4726687084348815 1.0 1.0 10 O14920 1 +G protein beta gamma signalling 0.5391893702754254 0.7073742801272395 0.4793339159068615 1.0 1.0 4 P31751 1 +Insulin receptor signalling cascade 0.4807368723351868 0.6925387362612107 0.4885990684792056 1.0 1.0 7 P62993,P31751 2 +Formation of rna pol ii elongation complex 0.4515643523835704 0.6897476167483528 0.4903529157354089 1.0 1.0 25 P23193,P35269,Q8IXH7,P13984,Q09161,P62875,P52434,O00267,P18074,Q14241 10 +Ros and rns production in phagocytes 0.4818205047100149 0.6895448075882171 0.4904804861057383 1.0 1.0 9 P21281,Q93050 2 +Rhou gtpase cycle 0.4731938490653291 0.6826752014540445 0.4948121030946311 1.0 1.0 18 O14964,O43396,Q92783,Q01082,Q03001,Q13813,P62993,Q14155 8 +O linked glycosylation 0.5284648284875142 0.6662672659209433 0.5052402846057606 1.0 1.0 4 Q10471,Q10472 2 +O linked glycosylation of mucins 0.5284648284875141 0.666267265920943 0.5052402846057609 1.0 1.0 4 Q10471,Q10472 2 +Sema4d induced cell migration and growth cone collapse 0.4725646738785735 0.656149754531532 0.511727774062908 1.0 1.0 7 P61586,P35579,O75116,Q7Z406,Q13464 5 +Zinc transporters 0.8052345343303886 0.6477314224592158 0.5171586769710099 1.0 1.0 2 Q8TAD4 1 +Metal ion slc transporters 0.8052345343303886 0.6477314224592158 0.5171586769710099 1.0 1.0 2 Q8TAD4 1 +Rnd2 gtpase cycle 0.4686095684142867 0.6350474620511166 0.5253974607098888 1.0 1.0 15 O43396,P38159,Q9Y2U8,Q86UP2,Q03001,Q07065 6 +Rho gtpases activate ktn1 0.468857565569765 0.6307847965210625 0.5281812455528576 1.0 1.0 9 Q9NSK0,Q86UP2,Q9H0B6,P61586,P33176 5 +Extracellular matrix organization 0.440942788958077 0.6281087509459653 0.5299327008135131 1.0 1.0 25 P13674,O15460,Q32P28,Q03001 4 +Rho gtpases activate iqgaps 0.4685191156828909 0.6266587107283303 0.530882974460618 1.0 1.0 10 P04350,Q13509 2 +Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.7980965329707664 0.6253810416804304 0.5317210018663951 1.0 1.0 2 P62942 1 +G beta gamma signalling through pi3kgamma 0.798096532970745 0.6253810416803627 0.5317210018664396 1.0 1.0 2 P31751 1 +Beta oxidation of octanoyl coa to hexanoyl coa 0.4999582621816668 0.6234210329534131 0.533007879889249 1.0 1.0 5 P11310 1 +Beta oxidation of decanoyl coa to octanoyl coa coa 0.4999582621816668 0.6234210329534131 0.533007879889249 1.0 1.0 5 P11310 1 +Tryptophan catabolism 0.7963970088375268 0.6200977613647842 0.5351934259420741 1.0 1.0 2 Q6YP21 1 +E2f enabled inhibition of pre replication complex formation 0.4627105822418204 0.6193783726993304 0.5356671252617762 1.0 1.0 6 Q9Y619 1 +Akt phosphorylates targets in the nucleus 0.7960571040108535 0.6190429069260734 0.5358880932122068 1.0 1.0 2 P31751 1 +Cytosolic sensors of pathogen associated dna 0.4621570769387172 0.6169781759577075 0.5372491207529948 1.0 1.0 17 O14920,P62875,P52434,P19474,Q9UJV9,P19388 6 +Post translational modification synthesis of gpi anchored proteins 0.4619188217828496 0.6159537614164322 0.5379250375750098 1.0 1.0 6 Q92643 1 +Phase i functionalization of compounds 0.4651554756071221 0.6111725640750455 0.5410853445948729 1.0 1.0 13 Q16850,P30837 2 +Caspase mediated cleavage of cytoskeletal proteins 0.4599989791204821 0.6076677931789332 0.5434078278969445 1.0 1.0 6 P35611,P08670 2 +Activation of atr in response to replication stress 0.4559413783639888 0.6053310316765537 0.5449590665337771 1.0 1.0 19 P24941,P35250,Q13416,P15927,Q9Y619,Q14566,P33991 7 +Nuclear signaling by erbb4 0.5812358486407894 0.5937946984358671 0.5526494353897555 1.0 1.0 3 Q92542 1 +Cristae formation 0.4436198915158172 0.5826411186934826 0.5601349188244982 1.0 1.0 22 Q13505,P00846,Q6UXV4,Q9NX63,Q16891,O75431,Q9NVH1 7 +Hiv elongation arrest and recovery 0.4506250355936606 0.5682380579564512 0.569873332536526 1.0 1.0 18 P35269,Q8IXH7,P13984,P62875,P52434,O00267,P23193,Q14241 8 +Lysine catabolism 0.4517535911848311 0.5654492272377358 0.571768249427548 1.0 1.0 7 P49419 1 +Ctla4 inhibitory signaling 0.4490805794977337 0.5610557751561049 0.574759515332651 1.0 1.0 6 P31751 1 +Sars cov infections 0.3208290065909323 0.56100749015697 0.5747924310849468 1.0 1.0 60 Q99720,Q13547,Q8NEB9,Q13724,Q8WXI9,Q8TBF4,Q9Y3E7,Q10472,P62942,P05026,O60885,Q13330 12 +Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.4504728636010692 0.5599721758953895 0.5754984164333095 1.0 1.0 7 P11310 1 +Creb1 phosphorylation through the activation of adenylate cyclase 0.570089289750724 0.5563347614920564 0.5779820278591168 1.0 1.0 3 P16220 1 +Pka mediated phosphorylation of creb 0.5700892897507239 0.5563347614920554 0.5779820278591175 1.0 1.0 3 P16220 1 +Foxo mediated transcription 0.4517930438016505 0.5552081078406436 0.578752323826907 1.0 1.0 9 P31751 1 +Rhov gtpase cycle 0.4471262205359007 0.5430741016463624 0.5870787832462412 1.0 1.0 17 O43396 1 +Translation of replicase and assembly of the replication transcription complex 0.4437564946188441 0.5386657948015272 0.5901174796363131 1.0 1.0 6 Q8WUX9,Q8NEB9,Q9Y3E7 3 +Peroxisomal protein import 0.4444829222080609 0.5302946698506418 0.5959076416942148 1.0 1.0 17 Q9BY49 1 +Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.4441105585395472 0.5268917562549281 0.5982687589295224 1.0 1.0 8 Q9UIV1 1 +Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.4463347330003711 0.5242129233559389 0.6001304532800584 1.0 1.0 12 Q13547,Q96KQ7,Q8WXI9 3 +Gene silencing by rna 0.2975077670416299 0.5204387831581145 0.602757784700092 1.0 1.0 46 Q8N2A8,Q8N1F7,Q8NFH4,Q8NFH5,Q5SRE5,P62875,P52434,Q9UPY3,O15397,Q15631,P12270 11 +Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.4441180769222905 0.5182156547752738 0.604307813485772 1.0 1.0 10 Q13547,Q03164 2 +Metabolism of porphyrins 0.4428100076835091 0.5163767346239377 0.6055913117804805 1.0 1.0 9 Q7KZN9,P30519 2 +Signaling by insulin receptor 0.4412913637419988 0.5149592242748638 0.6065815140054258 1.0 1.0 17 P36543,Q93050,P21281,P62993,P31751 5 +Mecp2 regulates neuronal receptors and channels 0.4386359949232409 0.5100082164294988 0.6100457055100506 1.0 1.0 7 Q13547,P16220 2 +Interferon gamma signaling 0.4420756845565959 0.5052713319532248 0.6133682753088734 1.0 1.0 12 P42224,P01889,P19474,O15344,P10321,P04439 6 +Signaling by egfr 0.4414633442071882 0.5040281910100406 0.614241566788714 1.0 1.0 11 O14964,Q92783,Q13685,P41240,P62993 5 +Proton coupled monocarboxylate transport 0.7511896668932725 0.4856397705206706 0.6272225936517071 1.0 1.0 2 P53985 1 +Signaling by fgfr2 0.4214593377538174 0.4813063936649756 0.6302987536016769 1.0 1.0 23 P35269,P13984,Q09161,P62875,Q01085,P31483,P52434,P62993,P19388 9 +Signaling by fgfr 0.4214593377538174 0.4813063936649756 0.6302987536016769 1.0 1.0 23 P35269,P13984,Q09161,P62875,Q01085,P31483,P52434,P62993,P19388 9 +Mitotic telophase cytokinesis 0.4359985294166975 0.4785592460241986 0.6322522168095992 1.0 1.0 12 Q7Z5K2,O95235,Q02241,Q29RF7,Q8WVM7 5 +Insulin receptor recycling 0.4336283442306083 0.4732289050786186 0.63604987780408 1.0 1.0 10 P36543,P21281,Q93050 3 +Mitotic prophase 0.3081149899944178 0.4660347455973279 0.6411906302267081 1.0 1.0 58 Q9UPP1,Q8N1F7,Q8NFH4,Q8NFH5,Q5SRE5,Q9Y2U8,Q86Y07,Q01105,O60763,Q08379,O43768,P30154,P12270,P50402 14 +Lysosome vesicle biogenesis 0.4331157779164493 0.4660243338086331 0.6411980827716273 1.0 1.0 12 O14964,P09496,Q9BXS5,Q00610,Q10567,P51809,P11142,O43633 8 +Ptk6 regulates proteins involved in rna processing 0.7440516655336533 0.4656029160557065 0.6414997553054269 1.0 1.0 2 P23246 1 +Rhod gtpase cycle 0.4151166923410038 0.4644543917469695 0.6423222285620347 1.0 1.0 24 Q8NHP6,Q86Y07,Q9Y2U8 3 +Downregulation of smad2 3 smad4 transcriptional activity 0.424737388755028 0.4607583164956845 0.644972010619878 1.0 1.0 6 Q13547 1 +Signaling by the b cell receptor bcr 0.2893663588309194 0.4559170350858822 0.6484496391449666 1.0 1.0 45 P28070,O95999,O14920,P28072,O00231,P62942,P49721,P28074,P62993 9 +Golgi to er retrograde transport 0.3156018788440706 0.4493878907742452 0.6531518651002033 1.0 1.0 65 Q10471,A2RRP1,Q9H2M9,Q99747,Q9Y678,Q15042,Q15102,O75935,P61923,Q6NUQ1,Q10472,Q02241,Q9H0B6,Q9NP72,Q9BUF5,P33176,O95235,Q9Y6G9,Q8TD16,O15260,Q9NSK0,P04350,Q13509 23 +Cell cell communication 0.4069009431329103 0.4386443291402298 0.660919271334103 1.0 1.0 25 P55196,Q01082,Q03001,Q9Y5K6,Q08722,Q13813,Q15404,P62993,O60716,Q05397 10 +Runx2 regulates bone development 0.4505192888376751 0.43790730428552 0.661453480468158 1.0 1.0 5 Q96PK6 1 +Intraflagellar transport 0.4140001599377546 0.3973036452373971 0.6911435596275908 1.0 1.0 9 P04350,Q9BUF5,Q13509,Q9BW83 4 +Signaling by kit in disease 0.4519033303362443 0.3962495113861236 0.6919209693280752 1.0 1.0 4 P62993 1 +Hdms demethylate histones 0.4383361671710566 0.3955824996085913 0.6924130494699656 1.0 1.0 5 Q8NB78 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.4154844050586735 0.3952852599314964 0.692632376405856 1.0 1.0 17 P01889,P04439,Q9NZ08,O95486 4 +Wnt ligand biogenesis and trafficking 0.4349307844904642 0.3840387786478042 0.7009497059721912 1.0 1.0 5 O75436 1 +Mhc class ii antigen presentation 0.2847549864655169 0.375139743153584 0.7075565409709714 1.0 1.0 48 O15020,O95486,O95235,Q9NSK0,P04350,Q13509,Q02241,Q9H0B6,Q9Y6G9,Q9BUF5,Q14203,Q10567,P33176,P52907,O75935 15 +Dna replication initiation 0.4256210506974048 0.3531609172236837 0.7239678059722388 1.0 1.0 5 Q9NRF9 1 +Prevention of phagosomal lysosomal fusion 0.4370468142400727 0.3502205548680416 0.7261731818682191 1.0 1.0 4 O14964 1 +Unfolded protein response upr 0.3080957117593815 0.339247928617628 0.7344229659394015 1.0 1.0 40 Q9NWM8,P43307 2 +G alpha s signalling events 0.6930659415363738 0.333810814472437 0.7385223223084689 1.0 1.0 2 P08754 1 +Deadenylation of mrna 0.4021319461474916 0.3336563397017991 0.7386388991200237 1.0 1.0 15 O75175,Q9UIV1,P23588 3 +Piwi interacting rna pirna biogenesis 0.3957798860572663 0.3271897089029168 0.7435244040256805 1.0 1.0 9 P62875,Q8N2A8,P52434 3 +Estrogen dependent gene expression 0.3659536732206736 0.3237551955165673 0.7461233794547699 1.0 1.0 30 Q13547,P35269,P52292,P13984,Q9UQE7,P62875,P52434,Q13951,Q8WVM7 9 +Processive synthesis on the c strand of the telomere 0.393349930041368 0.3181907018504705 0.7503402853898362 1.0 1.0 9 P51530,P15927 2 +Aggrephagy 0.3976067127551066 0.3173486708003989 0.7509790504534228 1.0 1.0 13 P04350,Q9BUF5,Q13509,P08670 4 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.4896293777626753 0.3149453225079926 0.7528031689520687 1.0 1.0 3 P07900,P00374 2 +Endosomal sorting complex required for transport escrt 0.396059365758173 0.3140682111467473 0.753469232663881 1.0 1.0 12 O14964,Q9NP79,Q8WUX9,Q92783,Q9NZZ3,Q9Y3E7,Q9UN37,O75351 8 +Processing of intronless pre mrnas 0.396303695826731 0.3099609168794405 0.7565906774009254 1.0 1.0 15 Q8N684,P51003,Q09161,Q6UN15,Q92797,Q86U42 6 +Negative regulation of the pi3k akt network 0.3948346869292343 0.3093768306635608 0.7570348929123114 1.0 1.0 12 P62993,P30154,P31751 3 +P38mapk events 0.4865147539294181 0.3068511804204601 0.7589566498478071 1.0 1.0 3 P11233 1 +Golgi cisternae pericentriolar stack reorganization 0.3914649878480489 0.305457287733314 0.7600178958524593 1.0 1.0 10 Q08379 1 +Muscle contraction 0.3704875873803234 0.3036258771041076 0.7614129346662568 1.0 1.0 28 P20020,O60504,P09493,P05026 4 +Fatty acid metabolism 0.2899189408649854 0.302382314652085 0.76236063498474 1.0 1.0 58 Q9BY49,Q16836,Q15165,O43772,P23786,P11310,Q8N8N7 7 +Er quality control compartment erqc 0.4091303199902384 0.3010848053413187 0.7633498273365475 1.0 1.0 5 Q86TM6 1 +P75ntr regulates axonogenesis 0.4837050746525508 0.2996421397144787 0.7644501373744754 1.0 1.0 3 P61586 1 +Sars cov 1 infection 0.3905900984931183 0.2874205452468974 0.7737903317288612 1.0 1.0 16 P17844,Q8NEB9,Q8WUX9,Q13724,P14314,Q8TBF4,Q9Y3E7,Q10472,P49840,O43633 10 +Sensory processing of sound 0.3895694298301335 0.287092949656421 0.7740411504158677 1.0 1.0 18 P20020,P35241,Q01082,Q12965,Q13813,P52907,P23634 7 +Protein folding 0.347407384446899 0.2719489700639049 0.7856612569669179 1.0 1.0 32 Q15477,P04350,O15212,Q9UHV9,Q13509,P78371 6 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3803015638831328 0.2714155520659936 0.7860714420023944 1.0 1.0 9 Q9UJX5,Q9UJX3,Q13042 3 +Tp53 regulates transcription of cell cycle genes 0.3863436409545395 0.2706224369703158 0.7866814373474291 1.0 1.0 16 O75175,Q9UIV1 2 +Mtor signalling 0.3840547272508162 0.2620172569018765 0.7933081377656861 1.0 1.0 15 P31751,P23588 2 +Mitotic prometaphase 0.3145254899694083 0.2613629936032933 0.7938125922607178 1.0 1.0 81 Q7Z5K2,Q9BSJ2,O95684,P04350,Q8NFH4,Q13509,Q9UQE7,O43805,Q7Z460,Q9Y6G9,Q9H6D7,Q9BUF5,Q9Y266,Q13257,Q29RF7,P30154,O75935,Q8WVM7 18 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.2901961574250372 0.2606790932332929 0.7943399899464079 1.0 1.0 41 P28070,Q03164,P28072,O00231,P49721,P28074,Q13951 7 +Hcmv early events 0.2964781644845921 0.2529995559040967 0.8002685563736378 1.0 1.0 40 Q8N1F7,Q8NFH4,Q8NFH5,Q5SRE5,P04350,Q13509,Q9Y6G9,P83916,Q9BUF5,P12270 10 +Processing of smdt1 0.3773798400431556 0.2497241417774297 0.8028006871466118 1.0 1.0 11 Q9H300 1 +Cd28 co stimulation 0.3717499072185865 0.2493834283610481 0.8030642025438357 1.0 1.0 8 P31751 1 +Initiation of nuclear envelope ne reformation 0.380115085203655 0.2487593289651354 0.8035469530647212 1.0 1.0 18 P63151,Q8NC56,P02545,Q86Y07,Q9Y2U8,P42166,P50402 7 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.2925203575134236 0.2473005131017828 0.804675661721246 1.0 1.0 65 P00403,P03886,O96000,P00846 4 +Dual incision in tc ner 0.3586603268047981 0.2435378853754397 0.8075887400821147 1.0 1.0 28 P35250,P23193,P15927,Q9NRF9,P62875,P52434,P18074,P19388,Q07864,O60306 10 +Dna methylation 0.397278911564622 0.2405857616639315 0.8098761866414506 1.0 1.0 4 P16104,Q96T88,P26358 3 +Cell junction organization 0.3780337730024173 0.2394329906167413 0.8107698510064396 1.0 1.0 15 Q03001 1 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.3725289706884672 0.2385361507150047 0.8114652801776239 1.0 1.0 10 Q13042,Q9UJX2,Q13309,Q9UJX3,Q9UJX4,Q16763,P30260,Q9UJX5,Q9H1A4 9 +Transcriptional regulation by e2f6 0.3624371415824864 0.2359090702506858 0.8135032298349212 1.0 1.0 6 Q96KQ7,P31350,Q9UBK9 3 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3602195312467903 0.2349996352018742 0.8142090163604043 1.0 1.0 27 Q13409,P04350,Q13509,Q9Y6G9,Q9BUF5,Q14203,Q13451,P52907,O75935 9 +Rna polymerase i transcription initiation 0.3759290584611978 0.2323402381373348 0.8162737618696532 1.0 1.0 18 Q13547,Q8WXI9,Q96KQ7,P62875,P52434,P18074,Q13330 7 +Stimuli sensing channels 0.3713664088402556 0.2290620586441586 0.8188206822853639 1.0 1.0 11 Q99576,Q9NW15 2 +Cyclin d associated events in g1 0.3676314361222717 0.2286662311633243 0.8191283430322096 1.0 1.0 9 P30154,P24941,P63151 3 +Ion homeostasis 0.3708793388545487 0.227416964170888 0.8200995303411489 1.0 1.0 11 P20020,P05026 2 +Sensory perception 0.3666092577714879 0.2273963058261896 0.8201155925798986 1.0 1.0 24 P20020,P35241,Q01082,Q12965,Q13813,P52907,P23634,P09455 8 +Downstream signaling events of b cell receptor bcr 0.2700669164127933 0.2243641519707351 0.8224739622328605 1.0 1.0 43 P28070,O95999,O14920,P28072,O00231,P62942,P49721,P28074 8 +Cilium assembly 0.2739968595946249 0.2240982958172236 0.8226808185040277 1.0 1.0 53 O95684,P04350,Q13509,O43805,Q9H6D7,P78371,O75935,Q9NV70 8 +Formation of incision complex in gg ner 0.3692870184693103 0.2220691206966762 0.8242600758143972 1.0 1.0 11 P35244,P61088,P18074,P15927 4 +Apoptotic factor mediated response 0.3621212309768102 0.218225538409663 0.8272533877862247 1.0 1.0 8 Q9NR28 1 +Irf3 mediated induction of type i ifn 0.3792665848655104 0.216319681015166 0.8287385689978868 1.0 1.0 5 Q9UJV9,P12956 2 +Organelle biogenesis and maintenance 0.3174918390716794 0.215683999612702 0.8292340741403761 1.0 1.0 88 P00846,Q6UXV4,O43805,Q9NVH1,P48735,P78371,O75935,O95684,Q7Z460,Q68CZ6,Q9BUF5,Q13505,Q9NX63,Q16891,O75431,P16220,P04350,Q13509,P06576,Q9H6D7,Q9NV70 21 +Extra nuclear estrogen signaling 0.3662592477428896 0.2120294569807621 0.8320840533992673 1.0 1.0 11 P31751 1 +Notch4 intracellular domain regulates transcription 0.6346023113528241 0.2111642388050776 0.8327591148372027 1.0 1.0 2 Q13573 1 +Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0.6346023113528241 0.2111642388050776 0.8327591148372027 1.0 1.0 2 Q13573 1 +Runx3 regulates notch signaling 0.6346023113528241 0.2111642388050776 0.8327591148372027 1.0 1.0 2 Q13573 1 +Notch2 intracellular domain regulates transcription 0.6346023113528169 0.2111642388050642 0.8327591148372131 1.0 1.0 2 P16220 1 +Translocation of slc2a4 glut4 to the plasma membrane 0.3358653478526878 0.2087524422702448 0.8346414988835411 1.0 1.0 32 P61026,P04350,Q9UIQ6,Q12965,Q13509,P31751,Q9NV70 7 +Regulation of tp53 expression and degradation 0.3618944698278052 0.2036801908230153 0.8386034231289863 1.0 1.0 10 P30154,P24941,P31751,P42771 4 +Linoleic acid la metabolism 0.6295037389530989 0.2020654320907345 0.8398655716044325 1.0 1.0 2 P33121 1 +Transcription coupled nucleotide excision repair tc ner 0.3084599124717944 0.2017235692360415 0.8401328357810973 1.0 1.0 37 P35250,P23193,P15927,Q99627,Q9BT78,Q9NRF9,P62875,P52434,P18074,P19388,Q07864,O60306 12 +Interleukin 7 signaling 0.6288239292998019 0.2008722539794842 0.8407984636160575 1.0 1.0 2 P51532 1 +Interleukin 23 signaling 0.6288239292998017 0.2008722539794839 0.8407984636160577 1.0 1.0 2 P07237 1 +Interleukin 21 signaling 0.6288239292997924 0.2008722539794677 0.8407984636160704 1.0 1.0 2 P42224 1 +Interleukin 9 signaling 0.6288239292997924 0.2008722539794677 0.8407984636160704 1.0 1.0 2 P42224 1 +Heme signaling 0.3725653430570217 0.1991436759340884 0.8421503569321183 1.0 1.0 5 P09601 1 +Myoclonic epilepsy of lafora 0.6274643099931916 0.1985000388809467 0.8426538543331992 1.0 1.0 2 P13807 1 +Signaling by ctnnb1 phospho site mutants 0.352517859084107 0.196850327595964 0.8439446658368113 1.0 1.0 7 P30154 1 +Beta catenin phosphorylation cascade 0.352517859084107 0.196850327595964 0.8439446658368113 1.0 1.0 7 P30154 1 +Dna double strand break repair 0.259767845972958 0.1952171181621759 0.8452229785134528 1.0 1.0 45 P35244,P24941,P35250,P61088,P15927,Q92878,P52292,O60934,Q9UQ84,Q9NWV8,Q9NRF9,Q9UNS1,P51530,O00213,Q07864 15 +Gab1 signalosome 0.4376430197831288 0.1948226659867688 0.8455317773858348 1.0 1.0 3 P62993 1 +Dna damage telomere stress induced senescence 0.3634816128529786 0.1937186272488022 0.8463962056925824 1.0 1.0 13 Q92878,P24941,O60934 3 +Acyl chain remodelling of pg 0.6230455472467744 0.1909207356958993 0.848587694251072 1.0 1.0 2 Q92604 1 +Scavenging by class a receptors 0.4352261135668177 0.1900541513586541 0.8492666970973872 1.0 1.0 3 P27797,P14625 2 +Mrna splicing 0.3658614768787719 0.1891422029085849 0.849981365272338 1.0 1.0 133 Q9Y5S9,P35269,Q8WWY3,O75937,Q96I25,P52756,Q8TBF4,P13984,Q09161,Q12874,Q6UN15,Q07955,Q13242,Q13573,P61978,P62312,O60306,O43390,Q7L014,Q08170,P62995,P51991,P84103,Q8IWZ8,Q9Y2W2,Q15637,O43290,Q92797,Q92733,Q13243,P67809,P38159,Q9Y3C6,Q92620,P62875,O75400,P35637,P19388,Q86U42,Q8N684,O43172,Q96BP3,Q53GS9,Q7RTV0,Q13247,P52434,O75934,P22626,Q13435,P52597,Q15459 51 +Notch hlh transcription pathway 0.373736465549183 0.186181768068214 0.8523022209580378 1.0 1.0 4 Q13547 1 +Platelet homeostasis 0.3531091001790967 0.1831860445920723 0.8546520438901064 1.0 1.0 9 P20020,P23634 2 +Cohesin loading onto chromatin 0.3526028831597999 0.1816719385106371 0.8558401892925642 1.0 1.0 9 Q7Z5K2,Q8WVM7,Q29RF7 3 +Cardiac conduction 0.3565773419630061 0.1758622578906608 0.8604021570073912 1.0 1.0 12 P20020,P05026 2 +Epha mediated growth cone collapse 0.3505475130963559 0.1755749294461349 0.8606278997625316 1.0 1.0 9 P61586,P35579,Q15375,O75116,Q7Z406,Q13464 6 +P75 ntr receptor mediated signalling 0.3577743976152645 0.1751763677001822 0.8609410530365535 1.0 1.0 13 Q13547,O14920,P61586,Q92542,Q14155 5 +Chl1 interactions 0.6125084976206724 0.1736537008856428 0.8621376259104436 1.0 1.0 2 P05556 1 +Atf6 atf6 alpha activates chaperones 0.6121685927940239 0.1731156466517255 0.8625605263884253 1.0 1.0 2 P27797 1 +Atf6 atf6 alpha activates chaperone genes 0.6121685927940239 0.1731156466517255 0.8625605263884253 1.0 1.0 2 P27797 1 +Ion channel transport 0.3239416638307805 0.1699395593382315 0.8650576697290213 1.0 1.0 33 P27105,P20020,Q99576,Q93050,P05026,P21281,P23634,Q9NW15 8 +Vegfr2 mediated vascular permeability 0.3485152723256646 0.1628545937978568 0.8706329223504385 1.0 1.0 10 O60716,P31751,Q13177 3 +Mrna splicing minor pathway 0.3308259748267103 0.161782255517742 0.871477326995411 1.0 1.0 31 P35269,P13984,Q8TBF4,Q09161,P62875,Q07955,P52434,P19388,Q13435,P67809 10 +Diseases of mismatch repair mmr 0.4199251955117314 0.1616289028325819 0.8715980953999729 1.0 1.0 3 P43246,P52701 2 +Calnexin calreticulin cycle 0.3474194959663799 0.1596664857051272 0.8731438026798597 1.0 1.0 10 Q86TM6 1 +Hcmv infection 0.2601557572578735 0.1562529678754647 0.875833627092744 1.0 1.0 49 Q8N1F7,Q8NFH4,Q8NFH5,Q5SRE5,P04350,Q13509,Q9Y3E7,Q9Y6G9,P83916,Q9BUF5,P12270,P61978 12 +Antigen processing cross presentation 0.2627333354047899 0.1557101353960608 0.876261507731853 1.0 1.0 51 P28070,P01889,O14920,Q9UIQ6,Q99436,P28072,O00231,P49721,P28074,P04439 10 +Rna polymerase i transcription 0.3523997661755682 0.1553854196853488 0.8765174779623952 1.0 1.0 22 Q13547,Q8WXI9,Q96KQ7,P62875,P52434,P18074,Q13330 7 +Regulation of lipid metabolism by pparalpha 0.3519354197238211 0.1529767014241284 0.8784166485838452 1.0 1.0 14 P11310,Q13503,Q9Y2W1,P23786 4 +Hdr through mmej alt nhej 0.3359724616739409 0.1502690073400423 0.8805523838729701 1.0 1.0 7 O60934 1 +Diseases of mitotic cell cycle 0.3480958488521476 0.1500435008361486 0.8807302950100222 1.0 1.0 12 P24941,Q9UJX5,Q9UJX3,Q13042 4 +Pi3k akt signaling in cancer 0.3459439472265171 0.1437297571148426 0.8857138723857412 1.0 1.0 12 P62993,P16220,P31751 3 +Copi mediated anterograde transport 0.2543644337750768 0.142474203161985 0.8867054543837773 1.0 1.0 46 Q14789,P04350,Q01082,Q99747,Q13509,Q9Y678,Q9Y6G9,Q9BUF5,Q13813,O60763,Q08379,O15020,O75935,P61923 14 +Hiv life cycle 0.2886642485039358 0.1372315367139317 0.8908477840254274 1.0 1.0 73 P35269,P13984,Q09161,Q92804,P12270,Q9NP79,Q8IXH7,Q8N1F7,Q8NFH4,O00267,P18074,Q5SRE5,Q9Y3E7,P62875,Q8NFH5,P52434,P17096,P23193,Q14241 19 +Hdacs deacetylate histones 0.3408529301967225 0.134815999471858 0.8927573555779469 1.0 1.0 11 Q13547,Q8WXI9 2 +Suppression of phagosomal maturation 0.3296849597040951 0.1339561651164925 0.8934372371118913 1.0 1.0 7 O14964 1 +Translesion synthesis by polk 0.3353047448750333 0.1329570452663814 0.8942273517253789 1.0 1.0 9 P35250,P15927 2 +Formation of tc ner pre incision complex 0.3461801851955597 0.1324501707111203 0.8946282337016647 1.0 1.0 22 P23193,Q7L5N1,Q99627,Q9BT78,Q13620,P62875,P52434,P18074,P19388,O60306 10 +Glyoxylate metabolism and glycine degradation 0.3398987278989916 0.1321717798897861 0.8948484216529526 1.0 1.0 11 O00330,P11177 2 +Defective cftr causes cystic fibrosis 0.2714808954749007 0.1285041427550428 0.8977500199629163 1.0 1.0 41 P28070,Q9BUN8,P28072,O00231,P49721,P28074 6 +Abc transporter disorders 0.2714808954749007 0.1285041427550428 0.8977500199629163 1.0 1.0 41 P28070,Q9BUN8,P28072,O00231,P49721,P28074 6 +Vegfr2 mediated cell proliferation 0.580217539089062 0.1277970216036451 0.898309607153404 1.0 1.0 2 P19174 1 +Apoptotic cleavage of cellular proteins 0.3460500094407711 0.1268570269908852 0.8990535592673001 1.0 1.0 20 P08670,Q9UDY2,Q16625,Q9P289,Q13813,P25054,P35611,P02545,Q05397 9 +Sensory processing of sound by outer hair cells of the cochlea 0.3424661572741967 0.1244951046091633 0.900923276183708 1.0 1.0 14 P35241,Q01082,Q12965,Q13813,P23634 5 +Sema4d in semaphorin signaling 0.3314430391832544 0.1229050198162033 0.9021823105291632 1.0 1.0 9 Q7Z406,P61586,O75116 3 +Transport of mature mrnas derived from intronless transcripts 0.2993191978054477 0.1171054030346671 0.9067765281963248 1.0 1.0 36 Q8N1F7,Q8NFH5,Q5SRE5,Q09161,Q6UN15,Q92797,P12270 7 +Ephrin signaling 0.3353482426244529 0.1157525132955798 0.90784868633929 1.0 1.0 4 Q14155 1 +Recognition of dna damage by pcna containing replication complex 0.3402916869473869 0.1145501056224934 0.908801729217743 1.0 1.0 15 P35244,P35250,P15927,Q9NRF9,Q07864 5 +Costimulation by the cd28 family 0.3372871533544164 0.1142249158518488 0.909059501176504 1.0 1.0 13 P62993,P30154,P31751,P41240 4 +E2f mediated regulation of dna replication 0.3326079822783961 0.112604254603927 0.9103443118207744 1.0 1.0 11 Q9Y619,Q13416 2 +Signaling by notch1 pest domain mutants in cancer 0.3200264612032455 0.1104358899835133 0.9120636911023814 1.0 1.0 7 Q13547,Q92542 2 +Aquaporin mediated transport 0.3859231553893282 0.1094281343101605 0.9128629197832056 1.0 1.0 3 Q99797,P10644 2 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.3859231553893282 0.1094281343101605 0.9128629197832056 1.0 1.0 3 P10644,P46940 2 +Negative regulators of ddx58 ifih1 signaling 0.3297536252987769 0.1074025928932336 0.9144695975755844 1.0 1.0 4 Q13526 1 +Activation of nima kinases nek9 nek6 nek7 0.3292517006802727 0.1066769386451311 0.9150452784841684 1.0 1.0 4 Q8TD19,P06493,P53350 3 +Apc c cdc20 mediated degradation of cyclin b 0.3300375042618428 0.1059762013487096 0.9156012344087194 1.0 1.0 11 Q13042,Q9UJX2,Q9UJX3,P06493,Q9UJX4,Q16763,P30260,Q9UJX5,Q9H1A4,Q9UJX6 10 +Phosphorylation of the apc c 0.3301500682128143 0.100419101739906 0.9200116054212926 1.0 1.0 12 Q13042,Q9UJX2,Q9UJX3,P06493,Q9UJX4,Q16763,P30260,Q9UJX5,Q9H1A4,Q9UJX6,P53350 11 +Viral messenger rna synthesis 0.3050453217504953 0.0976081438057913 0.9222434575677072 1.0 1.0 34 P35269,Q8N1F7,Q8NFH4,P13984,Q5SRE5,Q8NFH5,P62875,P52434,P12270 9 +Rhoh gtpase cycle 0.3358784920615502 0.0946850802970219 0.9245649689286932 1.0 1.0 21 P27105,Q8WWQ0,Q9UNZ2,Q13177,P41240,P11182,O75116,P52565 8 +Assembly of the orc complex at the origin of replication 0.3189924868574202 0.0926053038438154 0.9262171300001478 1.0 1.0 9 Q9Y619 1 +Role of second messengers in netrin 1 signaling 0.5418082936777782 0.086619888155563 0.9309736568549104 1.0 1.0 2 P19174 1 +Rna polymerase ii transcription termination 0.2512648498063732 0.0861007026294121 0.931386365082962 1.0 1.0 43 Q9Y5S9,Q8N684,Q08170,Q09161,P84103,Q6UN15,Q92620,Q07955,Q92797,Q13242,Q13243,Q86U42 12 +Creb phosphorylation 0.3137039731228074 0.0860793878273031 0.9314033089283758 1.0 1.0 4 P49137 1 +Met promotes cell motility 0.3126595930502169 0.0858773246308544 0.9315639372297876 1.0 1.0 8 Q05397 1 +Microrna mirna biogenesis 0.3209071902330961 0.0835902492850126 0.9333822197465108 1.0 1.0 11 P62875,P52434,Q9UPY3 3 +Nucleotide excision repair 0.2435747966732621 0.0829594389154447 0.9338837914497716 1.0 1.0 44 P35244,P35250,P23193,P15927,Q99627,Q9BT78,Q9NRF9,P62875,P52434,P18074,P19388,Q07864,O60306 13 +Smooth muscle contraction 0.3265567165270562 0.0811633729186237 0.9353120275584246 1.0 1.0 14 O60504 1 +Phospholipid metabolism 0.2701853712104319 0.080403201847965 0.935916580445144 1.0 1.0 40 Q8NAN2,Q6UWP7,Q9NPH0 3 +Generation of second messenger molecules 0.3583815028901702 0.0779185248964087 0.9378928634740332 1.0 1.0 3 Q13177,P19174 2 +Signaling by wnt in cancer 0.3123805288854559 0.0778398771429656 0.9379554252902392 1.0 1.0 9 P30154 1 +Nr1h2 and nr1h3 mediated signaling 0.3113886673833147 0.0766865420506383 0.9388729108994348 1.0 1.0 5 Q8NB78,O00767 2 +Complex i biogenesis 0.3227554092327025 0.0760503441302006 0.9393790453120668 1.0 1.0 27 O96000,P03886 2 +Recycling pathway of l1 0.3297029212365753 0.0749183398736055 0.9402796844552036 1.0 1.0 20 P04350,Q13509,P35241 3 +Ripk1 mediated regulated necrosis 0.3103918228279327 0.0735798976912111 0.9413446670909116 1.0 1.0 9 Q9UNE7,Q13546,P07900,Q16543,O75955,Q14254,O15294,Q8WUM4 8 +Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.3067455623934472 0.0699628496288405 0.944223228851681 1.0 1.0 5 Q92696,P24386 2 +2 ltr circle formation 0.3063659276601398 0.0694287691607278 0.944648329686662 1.0 1.0 5 P17096 1 +Protein protein interactions at synapses 0.3169583539891293 0.0684397915653489 0.9454355469825066 1.0 1.0 12 P10586 1 +Tp53 regulates transcription of dna repair genes 0.3253651745248936 0.0682417773184824 0.9455931709740272 1.0 1.0 24 P23193,P35269,Q8IXH7,P13984,P62875,P52434,O00267,P18074,Q14241 9 +Synthesis secretion and deacylation of ghrelin 0.3437606256375358 0.0648232411302026 0.9483147366190888 1.0 1.0 3 P61009,Q15005 2 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.3437606256375358 0.0648232411302026 0.9483147366190888 1.0 1.0 3 P61009,Q15005 2 +Interleukin 17 signaling 0.3246252207400638 0.0628306269243585 0.9499013772839386 1.0 1.0 18 P30154,P16220,O14920,P49137 4 +Mtorc1 mediated signalling 0.3111125819444499 0.0616017961763882 0.9508799465193704 1.0 1.0 11 P23588 1 +Termination of translesion dna synthesis 0.3197171417360555 0.0598714133920059 0.95225804784684 1.0 1.0 15 Q9NRF9,P35250,Q07864,P15927 4 +Neuronal system 0.2455004404284675 0.0596833022955904 0.9524078708631644 1.0 1.0 48 P10586,P52292,P04350,Q13509,Q96QD8 5 +Nuclear envelope breakdown 0.2664622851491415 0.058956714290717 0.9529865850971866 1.0 1.0 40 Q8NC56,Q8N1F7,Q8NFH4,Q8NFH5,Q5SRE5,Q9Y2U8,Q96EE3,Q86Y07,Q8TEM1,P20700,P42166,P50402,P12270,Q9BVL2,P02545,P53350 16 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.3009802437494094 0.0545559051972711 0.9564922689615304 1.0 1.0 9 P50402,P09601,P46379 3 +Unwinding of dna 0.3076426600829971 0.0543173202475169 0.9566823503618131 1.0 1.0 11 Q14566,P33991 2 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.3294109611703065 0.0541989155905833 0.9567766846498048 1.0 1.0 3 Q8NB78 1 +Polo like kinase mediated events 0.3291397483849048 0.0540180709228351 0.9569207667467868 1.0 1.0 3 Q99640,P53350 2 +Phosphorylation of emi1 0.3291397483849043 0.0540180709228345 0.9569207667467872 1.0 1.0 3 P06493,P53350 2 +G2 m dna replication checkpoint 0.3291397483849023 0.0540180709228334 0.956920766746788 1.0 1.0 3 Q99640,P06493 2 +Signaling by notch1 0.2946340431726515 0.0500429578441914 0.960088155776868 1.0 1.0 8 Q13547,Q92542 2 +Regulation of runx1 expression and activity 0.3226746937413256 0.0499153101458467 0.96018987678001 1.0 1.0 3 Q13951 1 +Slc mediated transmembrane transport 0.3208688172826435 0.0498438351316079 0.9602468346914148 1.0 1.0 22 Q96QD8 1 +Transcriptional regulation by ventx 0.312895299592521 0.0486144295839186 0.9612265704172428 1.0 1.0 14 Q13042,Q96KQ7,Q9UJX3,Q9HCE1,Q9UJX5,P42771 6 +Mitotic g2 g2 m phases 0.2868485828114412 0.046476056517795 0.9629308175904958 1.0 1.0 82 P63151,P24941,P28070,Q9BSJ2,O95684,P04350,Q99436,Q13509,P28072,O43805,Q7Z460,O00231,Q9H6D7,Q9BUF5,P49721,P28074,P30154,O75935 18 +Processing of dna double strand break ends 0.3191442602249721 0.0461189738505295 0.9632154231523125 1.0 1.0 23 P24941,P35250,P15927,O60934,Q9UQ84,Q9UNS1,P51530 7 +Cd28 dependent vav1 pathway 0.2865249019076655 0.0447231847383256 0.9643279534363522 1.0 1.0 5 P62993 1 +Processing of capped intronless pre mrna 0.3162619390694193 0.0441727408807534 0.9647667104633452 1.0 1.0 17 Q09161,Q92797,Q86U42,Q6UN15 4 +Activated tak1 mediates p38 mapk activation 0.284565753507757 0.0426148830273845 0.9660085313278696 1.0 1.0 5 P49137 1 +Orc1 removal from chromatin 0.2466524909607259 0.0411269087692623 0.967194722651432 1.0 1.0 51 P24941,Q13416,P28070,P28072,O00231,Q9Y619,Q14566,P49721,P28074,P33991 10 +Kinesins 0.3156072960812994 0.0396873976496088 0.968342348980798 1.0 1.0 18 O95235,P04350,Q9NSK0,Q13509,Q02241,Q9H0B6,Q9BUF5 7 +Signal amplification 0.2922937043448134 0.0354490601272673 0.971721664948482 1.0 1.0 3 Q13685 1 +Transport to the golgi and subsequent modification 0.2685048386454636 0.0326496487443905 0.9739539769416068 1.0 1.0 69 Q92734,O95486,Q01082,Q99747,Q9Y678,Q14203,P33908,O75935,P61923,Q14789,Q9BUF5,O15027,P52907,Q9Y296,Q9Y6G9,O60763,Q08379,O15020,Q5JRA6,O00743,Q12907,P04350,Q13509,Q13813 24 +Met interacts with tns proteins 0.4323589394969501 0.0319821695592976 0.9744862702538566 1.0 1.0 2 P05556 1 +Interferon signaling 0.2569143696057952 0.0319247011121306 0.9745321000379954 1.0 1.0 60 P42224,Q13526,P01889,Q8N1F7,P52292,Q8NFH4,Q5SRE5,Q8NFH5,P19474,P10321,P04439,P12270,O43432 13 +Integration of provirus 0.2738040709977681 0.0316936552813014 0.9747163546986316 1.0 1.0 6 P17096 1 +Sumo is transferred from e1 to e2 ube2i ubc9 0.4286199864038149 0.0312487501879225 0.9750711618502276 1.0 1.0 2 Q9UBE0 1 +Sumo is conjugated to e1 uba2 sae1 0.4286199864038149 0.0312487501879225 0.9750711618502276 1.0 1.0 2 Q9UBE0 1 +Processing and activation of sumo 0.4286199864038149 0.0312487501879225 0.9750711618502276 1.0 1.0 2 Q9UBE0 1 +Sema4d mediated inhibition of cell attachment and migration 0.2767766065963926 0.030625334036747 0.9755683379834388 1.0 1.0 3 P61586,Q9NWH9 2 +Transferrin endocytosis and recycling 0.2947002041386557 0.0294691615145468 0.976490413801101 1.0 1.0 11 P21281,Q93050 2 +Transcriptional regulation of white adipocyte differentiation 0.2773563631284571 0.0292716466093658 0.9766479399369156 1.0 1.0 7 Q13503 1 +Late endosomal microautophagy 0.2862473376316464 0.0285131172561858 0.9772529062257596 1.0 1.0 9 Q9Y3E7,O60664,P08670 3 +Maturation of sars cov 1 nucleoprotein 0.3990482664853879 0.0269626217342541 0.9784895467199152 1.0 1.0 2 P49840 1 +Signaling by bmp 0.3973487423521495 0.0267853471592967 0.9786309402988898 1.0 1.0 2 Q7Z3T8 1 +Respiratory electron transport 0.2469763321569282 0.0263675093916429 0.978964208884522 1.0 1.0 53 P00403,O96000,P03886 3 +Mitotic g1 phase and g1 s transition 0.2737920178419605 0.0262991319879586 0.9790187472462966 1.0 1.0 74 P28070,P63151,Q9NRF9,P49721,Q07864,P24941,Q13416,P15927,P28074,P31751,P31350,Q13547,Q99436,P28072,O00231,Q9Y619,Q14566,P33991,P30154 19 +Signaling by vegf 0.3092485649233309 0.0248221071445255 0.980196857538476 1.0 1.0 26 Q13685,P61586,O75116,Q9UQB8,O60716,P31751,P49137,Q05397 8 +Neurotransmitter clearance 0.3633582596872932 0.0243511129016696 0.9805725430012512 1.0 1.0 2 P05091 1 +Rho gtpases activate wasps and waves 0.3056628417594094 0.0239052072104139 0.9809282207177512 1.0 1.0 16 Q9UQB8,Q05397 2 +Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.2785318529852306 0.023684607746609 0.981104183801694 1.0 1.0 8 Q13547 1 +Gap filling dna repair synthesis and ligation in gg ner 0.3033017676119636 0.0234546238890418 0.9812876334078138 1.0 1.0 15 Q9NRF9,P35250,Q07864,P15927 4 +Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.3096532970768245 0.0230456450632103 0.9816138631096584 1.0 1.0 2 O00767 1 +Ca2 pathway 0.2787219578518083 0.0228628213106622 0.9817596969342108 1.0 1.0 2 Q9HCE1 1 +Activation of nmda receptors and postsynaptic events 0.3107141477355439 0.0221394439047093 0.982336722492686 1.0 1.0 23 P52292,P04350,Q13509,Q14155,Q9BUF5,P16220,Q15334 7 +Fcgr3a mediated il10 synthesis 0.266569244474332 0.0218507574845645 0.9825670052190942 1.0 1.0 6 P16220 1 +Positive epigenetic regulation of rrna expression 0.30253696987358 0.0200721116739832 0.9839858473226112 1.0 1.0 29 Q13547,Q8WXI9,Q96KQ7,Q12965,P62875,P52434,Q13330 7 +Mitochondrial calcium ion transport 0.3020471308483159 0.0164340209136726 0.9868881386458505 1.0 1.0 16 Q9H300 1 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.2621874645688816 0.0163621313073476 0.986945490541415 1.0 1.0 6 Q16850,P46939 2 +Ion transport by p type atpases 0.2936476282665947 0.0155981064886206 0.9875550163030264 1.0 1.0 13 P05026 1 +Rna polymerase i transcription termination 0.2769040025455936 0.014306969266172 0.9885850795307812 1.0 1.0 9 P62875,P52434,P18074 3 +Gastrin creb signalling pathway via pkc and mapk 0.2558975580286252 0.0090876564934183 0.9927491989919974 1.0 1.0 6 P62993 1 +Raf activation 0.276790255086701 0.0074302255103642 0.9940715923315502 1.0 1.0 10 Q9UQ13 1 +Pcna dependent long patch base excision repair 0.2972066792036437 0.0069270227182956 0.994473079721072 1.0 1.0 16 Q9NRF9,P35250,Q07864,P15927 4 +Tgf beta receptor signaling activates smads 0.2801790882054952 0.005869506832673 0.9953168380087204 1.0 1.0 11 Q9Y4E8 1 +Cell surface interactions at the vascular wall 0.2863630816217443 0.0033222959298671 0.9973491962475824 1.0 1.0 13 P08195,Q08722,P05026,P62993,P53985 5 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e8ff594234e0c0f5fa21921acd08a344f0883d7c --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retinoid cycle disease events", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Terminal pathway of complement", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFIP2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3B", "ATF7IP", "ATG3", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1B", "BCAP31", "BCAS2", "BCL10", "BCS1L", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRD1", "BRD2", "BRD4", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZB", "CARM1", "CARS", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2A", "CENPI", "CERS1", "CERS2", "CERS4", "CFL1", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTC", "CLU", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "COG4", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ9", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCD", "DCK", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DTNBP1", "DTX3L", "DUS2", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EHD1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENPP1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC6L", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTB", "FOXK1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGH", "GHDC", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNAI3", "GNL3", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILK", "IMMT", "IMP4", "IMPDH2", "INCENP", "INTS1", "INTS10", "INTS11", "INTS12", "INTS14", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "IST1", "ISYNA1", "ITGB1", "ITM2C", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRPPRC", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LTV1", "LYPLA1", "LYPLA2", "LZTFL1", "MAD2L1", "MAGED2", "MAN1A1", "MAN2B1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARCKS", "MARS", "MAT2A", "MAT2B", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED21", "MED24", "METAP2", "MFN2", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINPP1", "MIPEP", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO1C", "MYO1E", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCL", "NCSTN", "ND1", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSUN2", "NT5C2", "NT5C3B", "NUB1", "NUBP2", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGT", "PIGU", "PIK3C3", "PIK3R4", "PIN1", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLRG1", "PLS1", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "POFUT1", "POGLUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM2", "PUS1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP5", "RBBP6", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBP1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDX", "REL", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RNF114", "RNF20", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35B2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC7A1", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORBS3", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX5", "STX6", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SYMPK", "SYNE2", "SYVN1", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP2", "TAPBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TEX10", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126B", "TMEM87A", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP12", "TRMT10C", "TRMT6", "TRMT61A", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXNDC5", "TXNL1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBQLN1", "UBR4", "UBTF", "UBXN7", "UCHL5", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCRB1", "ZFYVE16", "ZNF512B", "ZNF638", "ZNF830", "ZW10"], "leading_proteins": ["AAMP", "ABHD10", "ACADM", "ACP6", "ACSL1", "ACTN1", "ADD1", "AFDN", "AKT2", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH7A1", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANO10", "AP1B1", "AP1M1", "APBB1", "APC", "APOOL", "AQR", "ARHGDIA", "ARHGEF7", "ATP1B1", "ATP2B1", "ATP2B4", "ATP5B", "ATP6", "ATP6V0A1", "ATP6V1B2", "ATP6V1E1", "BABAM1", "BAG4", "BAG6", "BAIAP2", "BCAS2", "BCL10", "BICD2", "BRD2", "BRD4", "BSG", "CALR", "CALU", "CAPZA1", "CBFB", "CBX1", "CCT2", "CD2AP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDK1", "CDK2", "CDK5", "CDKN2A", "CHCHD3", "CHD4", "CHID1", "CHM", "CHMP2A", "CHMP3", "CHMP5", "CHMP7", "CKAP4", "CLASP1", "CLTA", "CLTC", "CLU", "CNOT3", "CNOT7", "COPG1", "COPS4", "COPS6", "COPS8", "COPZ1", "COX15", "COX2", "CPSF7", "CPT1A", "CPT2", "CREB1", "CSK", "CTNND1", "CUL4B", "CYP51A1", "DBT", "DCTN1", "DCTN3", "DDX41", "DDX46", "DDX5", 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sha256:87e4036f7c6c14e3f6e97a8039b43499acd56ce164cd493651fe4063f541cd7a +size 73752 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a497c12256f9917d7c7fa10923aa35ca9ca114d1 --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Cytosine methylation 1 5 2.590690529133308 0.0095783583655713 2.0533980582524274 4.839805825242719 -0.0649747594084269 0.3077365108683944 1.3517565367896365 0.4045469252427314 1.4549970578233429 0.2999126289601936 0.0008300469730069 0.0032780640178306 0.0190953097419897 0.0682492372420068 +Vitamin a and carotenoid metabolism 2 5 2.33603084684506 0.0194896339083507 1.0606796116504855 4.106796116504855 0.9332890102257668 0.3070288768360753 0.8805930946368925 1.0255249317378814 1.0615219291263185 0.2652373693874932 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a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..35a4b5845912ca009abb23bb42f3cfa341dcf6bc --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 600, + "title": "Average number of proteins per term", + "value": 10.296666666666667 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6c19fb2092c2183a821bc26cfd8453dbf57e8975 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..860c44aa3df8a3be65991de097e2b9d20b40984a --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,163 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytosine methylation 0.974443772318407 2.590690529133308 0.0095783583655713 0.996894919163262 1.0 5 P48735 1 +Vitamin a and carotenoid metabolism 0.9093609522798332 2.33603084684506 0.0194896339083507 0.9999925644402172 1.0 5 O94788,P09455 2 +Histone modifications 0.8494053181109162 2.094803773992018 0.0361884394991351 0.9999999997515272 1.0 5 Q9H7B4,Q03164 2 +Mitochondrial long chain fatty acid betaoxidation 0.7542978001769017 2.0675383926483413 0.0386834504116835 0.9999999999475372 1.0 14 O43772,Q9BY49,P11310,P23786 4 +Statin inhibition of cholesterol production 0.8207185630854805 1.9771859593524783 0.0480206141031791 0.99999999999985 1.0 5 P35610,Q8WTV0 2 +Ketogenesis and ketolysis 0.8118361451462347 1.940488937052801 0.0523202973705052 0.99999999999999 1.0 5 O43772,P23786 2 +Resistin as a regulator of inflammation 0.7397321551225405 1.8926041395343272 0.0584105328614232 0.9999999999999998 1.0 6 O14920 1 +Type ii diabetes mellitus 0.8218663917924612 1.8622637449513884 0.0625659231441657 1.0 1.0 4 O00330 1 +Modulators of tcr signaling and t cell activation 0.6926823599727142 1.7051791377508367 0.088161019658721 1.0 1.0 10 O96000,P62993,O14920 3 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.8572347017758084 1.6328716775631391 0.1024959879811564 1.0 1.0 3 P31751 1 +Striated muscle contraction pathway 0.7313825958827227 1.60263482846684 0.109015299675067 1.0 1.0 5 P09493 1 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.6465999618231933 1.5030636804899338 0.1328226234279841 1.0 1.0 12 P13674,O15460,Q32P28,Q96AY3 4 +15q112 copy number variation syndrome 0.8044553121164882 1.429648115574077 0.1528180385182564 1.0 1.0 3 Q06787 1 +Sarscov2 and covid19 pathway 0.7794766700688127 1.3330902774293725 0.1825021796050476 1.0 1.0 3 Q8WTV0 1 +Acquired partial lipodystrophy barraquersimons syndrome 0.6908163265306217 1.324368331412736 0.1853807468087867 1.0 1.0 4 O60725,Q03252,P02545 3 +Cerebral organic acidurias including diseases 0.6624722067416268 1.3073059019852415 0.1911088405646153 1.0 1.0 5 P48735 1 +Translation factors 0.4525273147302886 1.305047998438237 0.1918765042383396 1.0 1.0 37 O75153,P55010,P23588,O75822,Q15056,O43432 6 +Allograft rejection 0.5979402507605309 1.2463243084755578 0.2126453570677811 1.0 1.0 10 P04439,Q9BY49,P08670 3 +Glucocorticoid receptor pathway 0.5983515762021806 1.2409669701746593 0.2146179508729027 1.0 1.0 6 P27105,Q99576 2 +Endochondral ossification with skeletal dysplasias 0.5938686982714763 1.219978289080673 0.2224731053170976 1.0 1.0 6 P22413,Q96QD8 2 +Endochondral ossification 0.5938686982714763 1.219978289080673 0.2224731053170976 1.0 1.0 6 P22413,Q96QD8 2 +Nanomaterial induced apoptosis 0.5899795475934279 1.201768036124522 0.2294534127850198 1.0 1.0 6 O95831 1 +Nucleotidebinding oligomerization domain nod pathway 0.5818726770117659 1.162557324950184 0.2450091536811789 1.0 1.0 8 O14920,Q9P0J0,Q96RT1 3 +Cellular proteostasis 0.6485460581368265 1.1490345592597253 0.2505417305620876 1.0 1.0 4 O15212 1 +Neuroinflammation 0.6409713505892467 1.117700701536461 0.2636948430498429 1.0 1.0 4 P00403 1 +Oxidation by cytochrome p450 0.61812871532857 1.1163359226487586 0.2642783704560498 1.0 1.0 5 Q16850,O43169 2 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.5586102559158845 1.0918512998410494 0.2748984663633289 1.0 1.0 15 Q13547,O60725,P55209,Q9Y2U8,Q9UPY3,P50402 6 +Notch signaling 0.5668092018226075 1.0906410341188135 0.2754308662002231 1.0 1.0 8 Q13547,O14641 2 +Familial partial lipodystrophy fpld 0.5660402677723659 1.0875922113148158 0.2767751706757515 1.0 1.0 7 O60725,P31751 2 +Retinoblastoma gene in cancer 0.3503939076466438 1.0714434795046108 0.2839700716395246 1.0 1.0 45 Q13547,P24941,P15927,P31350,Q9UQE7,Q16204,Q9Y619,Q14566,P16949,P33991,Q14527,Q07864,P09455 13 +Ranklrank signaling pathway 0.5538696531975651 1.056302976783794 0.2908298164122549 1.0 1.0 14 O14920,P31751 2 +Nrp1triggered signaling pathways in pancreatic cancer 0.5566635790798934 1.048632566631052 0.2943472611351092 1.0 1.0 11 P31751,Q05397 2 +Fatty acid betaoxidation 0.5281548773161409 1.0333996707398376 0.3014169005021281 1.0 1.0 21 O43772,P35610,P23786,P11310 4 +Nodlike receptor nlr signaling pathway 0.9163834126444504 1.021000905271114 0.3072540098134899 1.0 1.0 2 O14920 1 +Influence of laminopathies on wnt signaling 0.5501120813070318 1.011284665404978 0.3118802033233101 1.0 1.0 9 O60725,P50402,Q9UPY3 3 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.5405570605288305 0.9695008213952409 0.3322953705894096 1.0 1.0 11 O14920,P31751 2 +Small cell lung cancer 0.5389671528037622 0.9617136772370682 0.3361934500493408 1.0 1.0 11 O14920,P31751,Q05397 3 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.5376566149920142 0.9596210738202442 0.3372459588780465 1.0 1.0 12 P62993,O14920 2 +Overview of nanoparticle effects 0.6744506362065011 0.930278773346834 0.3522267652083604 1.0 1.0 3 Q05397 1 +Electron transport chain oxphos system in mitochondria 0.344906026556927 0.9108078688484073 0.3623966156895588 1.0 1.0 52 P00403,P03886,O96000,P00846 4 +Congenital generalized lipodystrophy cgl 0.8834126444595396 0.9063775981185316 0.3647360258327654 1.0 1.0 2 P31751 1 +Mecp2 and associated rett syndrome 0.5108039281914718 0.8963582788331376 0.3700614424176067 1.0 1.0 19 Q13547,Q9UQE7,P21359,Q13451,P35637,P16220,P52597,Q00013,P67809 9 +Cholesterol biosynthesis with skeletal dysplasias 0.5207820533275129 0.8796429034228349 0.3790527891421289 1.0 1.0 6 Q16850,Q15392 2 +Smc1smc3 role in dna damage cornelia de lange syndrome 0.5203507057468479 0.8734298138579067 0.3824288465031169 1.0 1.0 7 Q92878,O60934,Q9UQE7,O60216 4 +Novel intracellular components of rigilike receptor rlr pathway 0.5206706504102402 0.8721009215512501 0.3831533234619151 1.0 1.0 8 O14920 1 +Type 2 papillary renal cell carcinoma 0.5204532453656199 0.8710819512846842 0.3837094081919026 1.0 1.0 8 Q92733 1 +Transcription cofactors ski and skil protein partners 0.5734866524451899 0.8423525858154604 0.3995906244825211 1.0 1.0 4 Q13547 1 +Arachidonate epoxygenase epoxide hydrolase 0.8599592114208026 0.8265202008204215 0.4085090636806561 1.0 1.0 2 P34913 1 +Mfap5mediated ovarian cancer cell motility and invasiveness 0.5481403804002072 0.8191140490653668 0.4127213470630173 1.0 1.0 5 Q05397 1 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4756473296605938 0.804978001847172 0.4208323742193416 1.0 1.0 24 Q15392,Q15800,Q16850,Q14534,P48449,P35610 6 +Initiation of transcription and translation elongation at the hiv1 ltr 0.4998133802825016 0.7839529062610913 0.4330677440932593 1.0 1.0 6 Q13547,Q8IXH7 2 +Tolllike receptor signaling pathway 0.4954475791617559 0.7530566849586853 0.4514158517034294 1.0 1.0 12 O14920 1 +Tryptophan metabolism 0.4899995341441488 0.7405718969255869 0.4589530529698389 1.0 1.0 15 Q15392,P35610,O94788 3 +Oxidative phosphorylation 0.4316722859693618 0.7282584665466935 0.4664553817405856 1.0 1.0 30 O96000,P00846 2 +Cell migration and invasion through p75ntr 0.5207944789036931 0.7066877683648055 0.4797605324404284 1.0 1.0 5 P31751 1 +Dna mismatch repair 0.4798799749291141 0.7064186190310702 0.4799278454400852 1.0 1.0 17 P35250,P15927,Q9UQ84,Q9NRF9,Q07864 5 +Pdgfrbeta pathway 0.4829967670527672 0.7026682612754025 0.4822625114854184 1.0 1.0 7 P62993,P42224,P19525,P40763 4 +Wnt signaling in kidney disease 0.6086773237960698 0.6890672714631045 0.490780934812385 1.0 1.0 3 O14641 1 +Wnt signaling pathway and pluripotency 0.4791294666888785 0.6774319587948954 0.4981319269659934 1.0 1.0 13 P63151,P25054,O14641,P30154,O60716 5 +Prion disease pathway 0.4788000974392964 0.6736725019752801 0.5005195478003064 1.0 1.0 10 P16220,Q9UQE7,Q05397 3 +Cardiac hypertrophic response 0.4755592989862426 0.6578833264900751 0.5106131053918275 1.0 1.0 11 O14920 1 +Ddx1 as a regulatory component of the drosha microprocessor 0.5062624482468663 0.6483562882721396 0.5167545354379188 1.0 1.0 5 O60934 1 +Zinc homeostasis 0.8052345343303886 0.6477314224592158 0.5171586769710099 1.0 1.0 2 Q8TAD4 1 +Met in type 1 papillary renal cell carcinoma 0.4573552057052339 0.6400315268194877 0.5221521032338603 1.0 1.0 21 Q14241,P31751,Q92733 3 +Airway smooth muscle cell contraction 0.5036742043335831 0.6380900092407386 0.5234150897233816 1.0 1.0 5 P61586 1 +Chemokine signaling pathway 0.4636696027910326 0.6338895020306554 0.5261529371672162 1.0 1.0 18 P42224,O14920,P41240,P62993,P31751,Q05397 6 +Tgfbeta receptor signaling in skeletal dysplasias 0.5012576566649193 0.6285408927143578 0.5296496670195627 1.0 1.0 5 P62942 1 +Tgfbeta receptor signaling 0.5012576566649193 0.6285408927143578 0.5296496670195627 1.0 1.0 5 P62942 1 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.4615342443645489 0.5980815755837681 0.5497855032565389 1.0 1.0 9 Q05397 1 +Mthfr deficiency 0.4575254852342512 0.5902927368171946 0.5549944079669231 1.0 1.0 7 Q96KQ7,P49419 2 +Regulation of wnt bcatenin signaling by small molecule compounds 0.4901143734180509 0.5849868501615817 0.5585565587318628 1.0 1.0 5 O14641 1 +Pparalpha pathway 0.4553040162414283 0.5807006496007472 0.5614422238412105 1.0 1.0 7 P23786 1 +White fat cell differentiation 0.5769817732260639 0.5794058848374386 0.562315334244663 1.0 1.0 3 P16220 1 +Insulin signaling 0.3360652749623322 0.5647064450365592 0.5722734497449036 1.0 1.0 40 P22413,P10586,O14920,Q12965,P62993,P31751 6 +Ras signaling 0.4206285781396652 0.5605776014571109 0.5750855243414645 1.0 1.0 27 O14920,Q13177,Q13043,P61586,Q9UQ13,P21359,Q9UJF2,P62993,P11233,P31751 10 +Homologous recombination 0.4446584622875356 0.5424423490642235 0.587513812475952 1.0 1.0 6 O60934 1 +Hostpathogen interaction of human coronaviruses autophagy 0.488584798255455 0.5196616742859307 0.6032994037898765 1.0 1.0 4 Q9NT62 1 +Cholesterol biosynthesis pathway 0.4432853324153217 0.5118482172076464 0.6087572416324358 1.0 1.0 14 Q16850,P48449,Q15800,Q14534 4 +Nanoparticlemediated activation of receptor signaling 0.4334231361561087 0.4884070844969277 0.6252615247931994 1.0 1.0 7 Q05397 1 +Adipogenesis 0.4370552345494539 0.4827262735874332 0.6292901054039124 1.0 1.0 13 P42224,P43490,P40763,Q16822,P14174,P17096,O00767,P16220,P02545 9 +Nonalcoholic fatty liver disease 0.2950254022037474 0.4574787197861919 0.6473269944169706 1.0 1.0 49 O14920,P00403,O96000,P31751 4 +Ethanol effects on histone modifications 0.4182433822844779 0.4093826878740529 0.68225884236244 1.0 1.0 10 Q13547,O94788 2 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.4197863854339154 0.4078287628327833 0.6833993953925823 1.0 1.0 13 P55010 1 +Pi3kakt signaling pathway 0.3504723195375113 0.3937788603522019 0.69374431304316 1.0 1.0 35 P24941,P63151,P30154,O14920,P23588,P62993,P13807,P31751,Q05397 9 +Transcription factor regulation in adipogenesis 0.7141400407885826 0.3857367362577871 0.6996916528624242 1.0 1.0 2 P16220 1 +Neural crest cell migration during development 0.4087338019756406 0.382796135529217 0.701870927057457 1.0 1.0 8 P61586,P31751 2 +Complement system in neuronal development and plasticity 0.4103323511422787 0.3735071113648273 0.7087710535719471 1.0 1.0 11 P10909 1 +Proteasome degradation 0.30419237085326 0.3698969005055856 0.7114593109507301 1.0 1.0 41 P28070,P01889,Q99436,P28072,O00231,P49721,P28074,P04439 8 +Mitochondrial gene expression 0.4215068541467414 0.3398458030431667 0.7339726527404715 1.0 1.0 5 Q9P2K5 1 +Neural crest cell migration in cancer 0.3970623252813996 0.3319739904711241 0.7399088989208709 1.0 1.0 9 P61586,P31751 2 +Sterol regulatory elementbinding proteins srebp signaling 0.3712416741433469 0.3289801794543275 0.7421706694492498 1.0 1.0 29 P48449,Q14534,Q8WTV0 3 +G1 to s cell cycle control 0.3824818504237683 0.3288703780161878 0.7422536649463245 1.0 1.0 26 P24941,Q13416,P15927,Q9Y619,Q14566,P33991,P16220,Q07864 8 +Mitochondrial complex iv assembly 0.3979019550742302 0.3185054481338973 0.7501015626581373 1.0 1.0 13 P00403,Q7KZN9 2 +Epo receptor signaling 0.3869500768463225 0.3178867675379216 0.750570830356472 1.0 1.0 6 P62993 1 +Il9 signaling pathway 0.3869500768463225 0.3178867675379216 0.750570830356472 1.0 1.0 6 P62993 1 +Regulation of sister chromatid separation at the metaphaseanaphase transition 0.3882450452753125 0.2995743563804206 0.7645018469227389 1.0 1.0 9 Q13257,Q8WVM7 2 +Cytosolic dnasensing pathway 0.3886236353535507 0.2950421015522321 0.7679617180635576 1.0 1.0 10 P62875,O14920,P52434 3 +Progeriaassociated lipodystrophy 0.3858603223661155 0.2910153740161117 0.7710395613790975 1.0 1.0 9 P20700,O60725,Q03252,P02545 4 +Tnfalpha signaling pathway 0.3883164484225755 0.2907543077408001 0.7712392333656473 1.0 1.0 20 Q9NR28,O14920 2 +Il4 signaling pathway 0.3830323607264927 0.2749225814361292 0.7833757179066119 1.0 1.0 10 O14920 1 +Embryonic stem cell pluripotency pathways 0.3809527012865613 0.2544152428612629 0.799174776203587 1.0 1.0 13 P31751,O14641 2 +T cell receptor and costimulatory signaling 0.3993197278911547 0.2456870940702403 0.8059244634783516 1.0 1.0 4 P48729,P19174,P49840 3 +Apoptosis modulation and signaling 0.3788718011104676 0.2438462786869643 0.8073498767199561 1.0 1.0 18 O14920 1 +Pathways affected in adenoid cystic carcinoma 0.3771700359492904 0.2407898232714824 0.8097180174511089 1.0 1.0 13 Q9UBU8 1 +Dna irdamage and cellular response via atr 0.3463261670827866 0.2407700223509129 0.8097333649050271 1.0 1.0 31 P24941,P15927,Q92878,O60934,Q9UQ84 5 +Acute viral myocarditis 0.3781308173474749 0.2397916315655938 0.8104917947768273 1.0 1.0 15 P16220,Q9NRG0,P42224 3 +Tcell activation sarscov2 0.3769082922300392 0.237094274795541 0.8125836538094791 1.0 1.0 14 P62993,O14920 2 +Serotonin receptor 467 and nr3c signaling 0.3860802399728152 0.2345002802235785 0.8145966156659767 1.0 1.0 5 P49137 1 +Type i interferon induction and signaling during sarscov2 infection 0.6454792658055751 0.2314546976215779 0.8169615759775923 1.0 1.0 2 P42224 1 +22q112 copy number variation syndrome 0.3367463735915843 0.213434007620514 0.8309884573020314 1.0 1.0 32 Q96DF8,O94788 2 +Notch signaling pathway 0.3651126945266924 0.2082723328803414 0.8350163331243923 1.0 1.0 11 Q96T58,Q13547 2 +Micrornas in cardiomyocyte hypertrophy 0.3690657020079805 0.2080841344952284 0.8351632748676516 1.0 1.0 19 O14920,P31751 2 +Tcell receptor tcr signaling pathway 0.3693089070325095 0.2071028951958437 0.8359295010774637 1.0 1.0 18 P62993,O14920,P08670 3 +Il10 antiinflammatory signaling pathway 0.3747023400980533 0.2045440629980579 0.8379283624715617 1.0 1.0 5 P09601 1 +Estrogen receptor pathway 0.6288239292997884 0.2008722539794609 0.8407984636160757 1.0 1.0 2 Q15067 1 +Apoptosis 0.3638188774389061 0.1990546960565932 0.8422199593045008 1.0 1.0 12 O14920 1 +Type ii interferon signaling ifng 0.368359802848105 0.1887289861454884 0.8503052321682969 1.0 1.0 5 P01889 1 +Synaptic signaling pathways associated with autism spectrum disorder 0.3581961540464858 0.1861389569614222 0.8523357924878376 1.0 1.0 11 P31751 1 +Leptininsulin signaling overlap 0.6148878314072121 0.1774532435453175 0.8591523885532215 1.0 1.0 2 P40763 1 +Glioblastoma signaling pathways 0.3594530237112588 0.1741861493150566 0.8617191703852058 1.0 1.0 15 P24941,P31751 2 +Ccl18 signaling pathway 0.3456291541007457 0.1687580273153205 0.8659869740681732 1.0 1.0 8 Q86UE4,P42224,P00403,P08670 4 +Dna repair pathways full network 0.2842141513314645 0.1681752211568399 0.8664454339426917 1.0 1.0 40 P35250,P15927,O60934,Q9UQ84,Q9NRF9,P18074 6 +Interactome of polycomb repressive complex 2 prc2 0.4131183450280434 0.14996876795066 0.8807892561130828 1.0 1.0 3 Q9NYF8 1 +Dna replication 0.3410438379886107 0.1485007315105879 0.8819476086943316 1.0 1.0 27 P24941,P35250,Q13416,P15927,Q9Y619,Q14566,P33991,Q07864 8 +Circadian rhythm genes 0.2742007031900194 0.1465794188609078 0.8834639995648599 1.0 1.0 41 Q13547,P23246,P43490,Q9Y2W1,Q03164,Q13330,Q9BWF3,Q9UNS1,Q06210,P16220,P54802,Q8WXF1 12 +Male infertility 0.3515774666709742 0.1441927402396108 0.8853482734882774 1.0 1.0 18 Q15165 1 +Rac1pak1p38mmp2 pathway 0.3505031174883705 0.1428922255811281 0.8863752986526041 1.0 1.0 16 O14920,Q05397 2 +Focal adhesion pi3kaktmtorsignaling pathway 0.297479516572995 0.136580526255352 0.8913623700320676 1.0 1.0 37 O14920,P31751,P23588,Q05397 4 +Hedgehog signaling pathway wp4249 0.3998639918395122 0.1290082329124076 0.8973511343486611 1.0 1.0 3 Q13618,Q9UMX1 2 +Brainderived neurotrophic factor bdnf signaling pathway 0.257160957762111 0.1270669142572462 0.8988874377530236 1.0 1.0 43 O14920,P67809 2 +Nucleotide excision repair 0.3432513233183465 0.1171543297028089 0.9067377572347636 1.0 1.0 18 P35244,P35250,P15927,Q9NRF9,P18074,Q07864 6 +Pilocytic astrocytoma 0.3907092809504701 0.115868070459075 0.9077571012970048 1.0 1.0 3 P62993 1 +Thermogenesis 0.3283586281987195 0.1068985712614604 0.9148694466654588 1.0 1.0 28 O43772 1 +3q29 copy number variation syndrome 0.3218987563423723 0.0993874980315589 0.9208306087412734 1.0 1.0 9 O95684,P61088,Q09161,Q13177 4 +Interleukin11 signaling pathway 0.3289145081347717 0.0972599158911447 0.9225199875194916 1.0 1.0 12 P62993,P16220,O14920 3 +Hepatitis b infection 0.3346952591015552 0.0958168227436603 0.9236660562170356 1.0 1.0 23 O14920 1 +Methylation pathways 0.3634818089085373 0.0830605951709239 0.9338033580330454 1.0 1.0 3 P31153,Q9NZL9 2 +Pathways of nucleic acid metabolism and innate immune sensing 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Neural crest differentiation 0.3102657341972227 0.0733126308708443 0.9415573407670748 1.0 1.0 9 O14641 1 +Dna irdouble strand breaks and cellular response via atm 0.3275483959094601 0.0721086626664973 0.9425154323633425 1.0 1.0 23 Q92878,O60934,Q9UQ84 3 +Mitochondrial complex i assembly model oxphos system 0.3233219321104407 0.0711205887591997 0.9433017822009986 1.0 1.0 26 Q8IUX1,Q96CU9,O43676,Q9P0J0,Q9NX14,Q9NPL8,Q16718,O96000,Q7L592,P03886 10 +Tca cycle aka krebs or citric acid cycle 0.3199301827594004 0.0603863150306571 0.9518479577902884 1.0 1.0 15 P48735 1 +Bdnftrkb signaling 0.2990980532476287 0.0582881922823838 0.9535190727183902 1.0 1.0 8 P62993,Q15334 2 +Hippoyap signaling pathway 0.3087385243114521 0.0423554910350006 0.9662153094925984 1.0 1.0 3 Q13043,Q92597 2 +Breast cancer pathway 0.3179299040001228 0.0414154968646055 0.9669646586853604 1.0 1.0 22 P62993,O60934,P31751,O14641 4 +Dna damage response only atm dependent 0.3173309918339397 0.0403072413773372 0.9678481806880228 1.0 1.0 20 P62993,P61586,O14641,P25054,P31751 5 +Regulation of actin cytoskeleton 0.2919444615910415 0.038082725092784 0.9696217246974062 1.0 1.0 34 Q8NEB9,P35241,P61586,P41240,O75116,P25054,Q9UQB8,Q05397,Q14155 9 +Wntbetacatenin signaling pathway in leukemia 0.2790064647839374 0.0369420161961403 0.9705312385160614 1.0 1.0 5 P25054,P49841,P14923,P48729 4 +Nanoparticle triggered regulated necrosis 0.4381373215499751 0.0332158793779277 0.9735024351973134 1.0 1.0 2 Q13546 1 +Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.2992567621159786 0.0316360440648154 0.9747622987598156 1.0 1.0 12 Q86UE4,O14641 2 +Hedgehog signaling pathway wp47 0.4208021753908983 0.029868101340715 0.9761722459361226 1.0 1.0 2 Q9UMX1 1 +Calcium regulation in cardiac cells 0.3134052090684139 0.0289242588561531 0.9769249979443522 1.0 1.0 22 P62942,P20020,P05026 3 +Malignant pleural mesothelioma 0.2608390905418211 0.024287464356359 0.9806233121774924 1.0 1.0 64 Q4VCS5,Q96T88,Q13257,P49137,Q13177,Q02241,O14641,P25054,P24941,Q08722,Q13043,O15294,P62993,P08195,P16220,P31751,P42224,P23588,Q8NE86,Q05397 20 +Ras and bradykinin pathways in covid19 0.2074829931972853 0.0232386025856931 0.981459946502963 1.0 1.0 4 Q99829,P61586,Q13464 3 +Mitochondrial complex ii assembly 0.3116927260367158 0.0230661191396653 0.981597531501462 1.0 1.0 2 P21912 1 +Liver x receptor pathway 0.3096532970768245 0.0230456450632103 0.9816138631096584 1.0 1.0 2 O00767 1 +Pdgf pathway 0.2987869302629337 0.0195664232457 0.9843892490712548 1.0 1.0 14 P62993,P00403,P61586 3 +Il6 signaling pathway 0.283486827804977 0.0173406739066252 0.9861648373893226 1.0 1.0 10 Q13547,P62993 2 +Hepatocyte growth factor receptor signaling 0.284085313919327 0.0117824125984153 0.9905992124103278 1.0 1.0 11 Q05397 1 +Eukaryotic transcription initiation 0.2837524606427912 0.011266238652886 0.9910110322797596 1.0 1.0 11 P13984,P52434,P18074 3 +Oxidative damage response 0.23103096291255 0.0046404050327546 0.996297505756354 1.0 1.0 5 P12004,O95429,O95551,P42574 4 +Endometrial cancer 0.2847574265994335 0.0007725463851417 0.9993835972281058 1.0 1.0 13 P62993,P31751 2 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9483d43f66c8f748b53fba2b7dda9735730f9c4b --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Arylamine metabolism", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna for targeting cancer growth and vascularization in glioblastoma", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthesis ii from tryptophan", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Srf and mirs in smooth muscle differentiation and proliferation", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCD3", "ABCF1", "ABCF2", "ABHD16A", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APC", "APEX1", "APMAP", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARFIP2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARL2", "ARL3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG9A", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "BAG2", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCL10", "BCL2L13", "BCLAF1", "BCS1L", "BLVRA", "BLVRB", "BPTF", "BRD1", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP3", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2A", "CEBPZ", "CEP44", "CERS1", "CERS2", "CERS4", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CIP2A", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLTA", "CLTC", "CLU", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT10", "CNOT9", "CNP", "COA3", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "COQ9", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CREB1", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DARS", "DBNL", "DCAF7", "DCK", "DCP1A", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC1", "DSC3", "DSG2", "DSP", "DSTN", "DTX3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHBP1", "EHD1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "EMD", "EML4", "ENO1", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERBIN", "ERCC2", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC5", "EXOC6", "EXOC7", "EXOSC2", "EXOSC4", "EXOSC7", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GCC2", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGH", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNAI3", "GNS", "GOT1", "GOT2", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F2", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "ILK", "IMPDH2", "INF2", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF22", "KIF23", "KIF2C", "KIF4A", "KIF5B", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LPP", "LRPPRC", "LRRC59", "LSM2", "LSM4", "LSS", "LTA4H", "LUC7L", "LYRM7", "LZTFL1", "MACF1", "MAD2L1", "MAP1B", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MFN2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPDU1", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1C", "MYO1E", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCSTN", "ND1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NIPBL", "NKRF", "NME1", "NME2", "NONO", "NOP2", "NPC1", "NPC2", "NSDHL", "NSF", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC6", "OSBPL3", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PIGT", "PIK3C3", "PIK3R4", "PIN1", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PMAIP1", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLD1", "POLDIP2", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PSPH", "PTBP1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUM2", "PURA", "PUS1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QKI", "QPRT", "RAB10", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABGAP1", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RASAL2", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBP1", "RBPJ", "RCC1", "RCN1", "RDX", "RECQL", "REL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNF20", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAP18", "SAR1A", "SAR1B", "SARS", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDF2L1", "SDHA", "SDHB", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35B2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMYD3", "SNAP23", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR4", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TACO1", "TALDO1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCP1", "TDP2", "TECR", "TEDC1", "TELO2", "TFAM", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMED10", "TMEM126B", "TMEM165", "TMEM38B", "TMEM43", "TMEM70", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRIP4", "TSC22D3", "TSG101", "TSPO", "TTC19", "TTC26", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUFM", "TXNDC5", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE2N", "UBE3A", "UBR5", "UBTF", "UBXN7", "UCHL5", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNG", "UPF1", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VANGL1", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS11", "VPS16", "VPS4A", "WAPL", "WARS", "WDHD1", "WDR1", "WDR26", "WDR5", "WFS1", "WIPI2", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ACADM", "ACOX1", "ADAR", "AIFM1", "AKT2", "ALDH1A2", "ALDH7A1", "AMOT", "APC", "ARHGEF7", "ATG3", "ATP1B1", "ATP2B1", "ATP6", "BAG4", "BAIAP2", "BCLAF1", "CASP3", "CCDC6", "CD47", "CDK2", "CHRAC1", "CLU", "CLUH", "COX15", "COX2", "CPNE1", "CPT2", "CREB1", "CSK", "CSNK1A1", "CTNND1", "CUL3", "CYB5B", "CYP51A1", "DHCR24", "DIABLO", "DICER1", "DVL2", "EHMT2", "EIF2AK2", "EIF3J", "EIF4B", "EIF4G3", "EIF4H", "EIF5", "ELOA", "EMD", "ENPP1", "EPHX2", "ERBIN", "ERCC2", "ESS2", "EXO1", "FGFR1OP", "FKBP10", "FKBP1A", "FKBP5", "FMR1", "FOXRED1", "FUS", "GFPT1", "GRB2", "GSK3A", "GSK3B", "GTF2F2", "GYS1", "HDAC1", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMOX1", "HNRNPF", "ICMT", "IDH2", "IKBKB", "JUP", "KIF23", "KMT2A", "LEMD3", "LLGL1", "LMNA", "LMNB1", "LMNB2", "LSS", "MAD2L1", "MAPKAPK2", "MAT2A", "MAT2B", "MCM4", "MCM6", "MCU", "MIF", "MORF4L1", "MPP1", "MSMO1", "MTA1", "MTDH", "MYEF2", "MYO1E", "NAGLU", "NAMPT", "NAP1L1", "NBN", "NCBP1", "ND1", "NDRG1", "NDUFA13", "NDUFA5", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NELFCD", "NF1", "OGT", "ORC2", "P3H1", "P4HA1", "P4HA2", "PAK2", "PCK2", "PCNA", "PDHX", "PECR", "PFDN6", "PIK3C3", "PLCG1", "POLE", "POLE3", "POLR2H", "POLR2L", "PON2", "PPP2R1B", "PPP2R2A", "PRCC", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PSPC1", "PTK2", "PTPRF", "RAD21", "RAD50", "RALA", "RASAL2", "RBM4", "RBP1", "RDX", "RFC2", "RHOA", "RIPK1", "ROCK1", "ROCK2", "RPA2", "RPA3", "RRM2", "SCARB1", "SCD", "SDHB", "SFPQ", "SHOC2", "SLC25A15", "SLC25A20", "SLC30A5", "SLC38A2", "SLC3A2", "SMC3", "SMYD3", "SOAT1", "SPEN", "SQLE", "STAG1", "STAT1", "STAT3", "STK4", "STMN1", "STOM", "SUFU", "TDP2", "THRAP3", "TIMELESS", "TIMMDC1", "TMEM126B", "TPM1", "TSC22D3", "UBE2N", "UHRF1", "VIM", "YBX1"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..eb998ade52f9ee8eb79ddd4d1e9ebb057532bc59 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "nuclear_membrane", "1": "er"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..48b3f3fb1ffbf60798ab4c5618bf70295ef85aed --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5ccb538e41131a91167cb8c95bd60dd0d8474607022bf5300342ad29f424e51e +size 146845 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..006a210a70769d8100087feb2a3ea7c5dab8e579 --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:60f44e2b6cad606390cacd0f2ee6b01c707904ee1ec9376363f6dca7b9f2c33f +size 138921 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3e88d79021b948cd06754303572d5466a35ef008 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a64793ab00e2896251fc9e1c4b886768f13eefecdf3677e40517e3468da727d +size 64837 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..113acf5f3ae5cec5309c2776eba99bb8fd974639 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 91.47058823529412 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1bedebf5c044b3b84dcc764182e6d47defa73914 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1975711a2a1a50a20570d7d639f969d323908645 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +focal_adhesions 0.6103625405893361 1.297100841913428 0.194596491893912 0.9747518368471422 1.0 7 Q14155,P41240,Q05397 3 +nuclear_membrane 0.3254352102865913 0.1361216130123537 0.8917251418408918 1.0 1.0 31 Q8NFH5,P52292,Q9C0E2,Q9Y2U8,Q9NPA8,P12270,Q9H074 7 +er 0.2967412069274019 0.0969482477596795 0.9227674930636728 1.0 1.0 84 Q86TM6,Q8TCJ2,Q15392,O00264,Q9NPA0,P61026,Q16850,Q86Y07,Q9BZF1,P48449,P08240,O60499,O75845,Q07065 14 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..59bb8c45fdc5287234caa078d4ad92d761d0eb6f --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKAP8L", "AKR1A1", "AKT1S1", "AKT2", "ALDH16A1", "ALDH9A1", "ANAPC2", "ANAPC4", "ANKRD13A", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "APC", "ARF4", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGEF7", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARPC2", "ARPC3", "ATG3", "ATG9A", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1B", "BUD23", "BYSL", "C19orf53", "C8orf33", "CAD", "CALD1", "CALM3", "CAMK1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CASP3", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKN2A", "CHEK2", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP7", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLINT1", "CLNS1A", "CLPTM1", "CLTA", "CLTC", "CNN2", "COIL", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCP1A", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL2", "EBNA1BP2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC4", "EMC7", "EMG1", "ENO1", "ENY2", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FAM50A", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GNL2", "GNL3", "GOLGA2", "GOLT1B", "GORASP2", "GPR107", "GRB2", "GSK3A", "GSK3B", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPBP1", "HSPH1", "IDI1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF3", "ILK", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IST1", "KIAA0319L", "KIAA0368", "KIF11", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LAMP1", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LIG1", "LMAN1", "LMNA", "LMNB1", "LNPK", "LPCAT1", "LSS", "LTV1", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARK2", "MBOAT7", "MDH1", "MECP2", "MED21", "MED24", "METAP2", "MFN2", "MIF", "MKI67", "MMGT1", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MVK", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1E", "MYO6", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NDRG1", "NECAP1", "NECAP2", "NEK9", "NEMF", "NHP2", "NIFK", "NOL11", "NOM1", "NONO", "NOP10", "NOP2", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "OXSR1", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAK2", "PAK4", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PFDN6", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C3", "PIN4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "PPM1G", "PRKDC", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTGES3", "PTK2", "PTK7", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB23", "RAB24", "RAB2A", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB8B", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGRF", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "REEP4", "REEP5", "RER1", "RHOA", "RHOG", "RIOK1", "RIOK2", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "SACM1L", "SAE1", "SAR1A", "SAR1B", "SARS", "SBDS", "SC5D", "SCAMP1", "SCAMP2", "SCAMP4", "SCD", "SCFD1", "SCYL2", "SEC16A", "SEC22B", "SEC23A", "SEC24C", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35F2", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPD2", 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pval_100 pval_250 pval_500 +translation initiation factor 8 44 2.1859473261233173 0.0288194592367161 12.444174757281552 44.851941747572816 0.1145008827355917 0.6467304989659429 6.887394567659453 2.159854614961781 0.9002593912782545 0.3253626339773532 0.270648213584465 0.4688773052385803 0.0197625026052712 0.0036879765758405 +tubulin 2 6 2.0837649840842003 0.0371815498916539 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 1.0 1.0 0.0703212183088513 0.0547354250806853 +transmembrane signal receptor 3 8 2.0788475880922785 0.0376313613328853 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.0102615341834231 0.0615174189559832 0.1873239007657934 0.664071456208553 +oxidoreductase 6 40 1.9998731878731848 0.0455139590515447 12.558252427184469 43.60436893203884 0.9664652969079414 0.3656199292680728 5.072676172192643 3.8442089013841825 1.3118377214144643 0.3470065139863294 0.0011734825476199 0.0023682370591 0.0084996601315941 0.0923199749687444 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4f30041a219b1f42f1a21aaeca0154224f540265 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 157, + "title": "Average number of proteins per term", + "value": 12.980891719745223 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c00ac2f1d8db0e37ac3f1da210b9738074b00d93 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ae2527affed9cafdd228ee73ec5000c614e91f91 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,50 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +translation initiation factor 0.4578222992683834 2.1859473261233173 0.0288194592367161 0.9898586539187938 0.6496083246447752 44 O75153,P55010,P41214,P23588,O75822,Q01085,Q15056,O43432 8 +tubulin 0.7826484314400508 2.0837649840842003 0.0371815498916539 0.9973910160246088 0.6496083246447752 6 P04350,Q13509 2 +transmembrane signal receptor 0.7776515204522068 2.0788475880922785 0.0376313613328853 0.9975755707091616 0.6496083246447752 8 Q99720,Q8WUJ1,Q9UMX5 3 +oxidoreductase 0.4983828164401226 1.9998731878731848 0.0455139590515447 0.9993334629832712 0.6496083246447752 40 Q8N4Q0,O43396,O43676,O95831,P00403,O96000 6 +major histocompatibility complex protein 0.818707482993203 1.849518161771563 0.0643830277731551 0.9999709998432332 0.7392964923135559 4 P01889,P04439,P55899 3 +oxygenase 0.6769868975568852 1.6098986582476684 0.1074199819716701 0.9999999821514004 0.8700695239638897 7 Q16850,Q14534,P30519 3 +DNA helicase 0.6491420946408131 1.4832532359307538 0.138007141874928 0.99999999992517 0.8858964707748811 8 Q96S55,P12956,P18074 3 +histone modifying enzyme 0.6456602287719124 1.471831751899581 0.1410663170023696 0.9999999999571784 0.8858964707748811 9 Q9H7B4 1 +calcium-binding protein 0.6325654317404608 1.4008759057112858 0.1612511849723037 0.9999999999989764 0.9034256465311452 6 P09525 1 +amino acid transporter 0.6153547372251913 1.320521356434403 0.1866610104751487 0.9999999999999918 0.94534769821285 6 Q96QD8 1 +cytoskeletal protein 0.6052336530225358 1.273180233478543 0.2029540930718709 0.9999999999999996 0.9525233606649902 6 P27105,Q14141 2 +G-protein modulator 0.6440750154363722 1.2280391700970583 0.2194322641741539 1.0 0.9525233606649902 5 Q9H2M9,P24386 2 +nucleic acid metabolism protein 0.6386971039699294 1.204867924759392 0.2282542928115669 1.0 0.9525233606649902 5 P49750,Q9NYF8 2 +protein-binding activity modulator 0.6503401360544194 1.1564623845586923 0.2474920769709445 1.0 0.9927099754719736 4 O14737,Q9UNZ2,O14530 3 +phosphatase modulator 0.608214076839096 1.0737567079916672 0.2829317377880587 1.0 0.9968362982493664 5 Q15435 1 +RNA splicing factor 0.3827817118654464 1.0286863691548307 0.3036270772464717 1.0 0.9968362982493664 71 Q96G21,Q12872,Q8WWY3,Q15459,Q96I25,Q09161,Q12874,Q07955,O43719,Q13242,Q13573,P62312,Q08170,P84103,Q8IWZ8,Q8IXT5,Q15637,Q13243,Q16629,Q9BWU0,Q12849,P31942,P55795,O43172,Q96PU8,Q07666,Q13247,Q9BWF3,O75934,Q96PK6,Q13435,P52597,Q9P2K5,Q9Y4C8 34 +protein modifying enzyme 0.5300503296043219 1.02155240511211 0.3069927939326584 1.0 0.9968362982493664 20 P13674,Q92791,O60725,O15460,Q15102 5 +dehydrogenase 0.365512775446793 0.9643810731172728 0.3348549077665816 1.0 1.0 63 O75874,O94788,P11310,P30837,P49419,P48735,P03886 7 +calmodulin-related 0.5335519837712298 0.9392993719080988 0.3475770610038626 1.0 1.0 12 Q15293,Q14257,O43852 3 +primary active transporter 0.4609145977865797 0.7447417984533886 0.4564278254972347 1.0 1.0 25 Q9BUN8,O60888 2 +viral or transposable element protein 0.8327668252889194 0.7361749988654126 0.461624205163937 1.0 1.0 2 Q9H2J4 1 +GTPase-activating protein 0.4871741924207785 0.7134095081271505 0.475592391187174 1.0 1.0 12 Q8TC07,O60343,Q15042,Q9UJF2,Q66K14 5 +C2H2 zinc finger transcription factor 0.5264162816188193 0.6584861034714778 0.5102258236825548 1.0 1.0 4 O95785 1 +membrane traffic protein 0.3310126269254735 0.620445500783586 0.534964524025743 1.0 1.0 63 Q13432,Q12768,Q99747,Q9NX40,Q96D71,O60313,Q9NP79,Q9HD26,P43307,P40222,P40855,Q8WUX9,Q5THJ4,Q9NZZ3,Q9Y3E7,Q9UPT5,Q9Y296,Q10567,O60763,Q08379,Q00765,O75436,Q5JRA6,O00429,Q12907,O14976,P30040 27 +SNARE protein 0.4523971656818906 0.5578447312005785 0.5769504147741005 1.0 1.0 9 O15400,O60499 2 +DNA-binding transcription factor 0.4460581551892688 0.5551298960126816 0.5788058153516671 1.0 1.0 19 Q9NRG0,P42224,Q8WXI9,Q9NPA8,Q8IVW6,Q03701,Q13951,Q00577 8 +transporter 0.3036806350595077 0.4497187561815955 0.6529132453654753 1.0 1.0 56 P54105,P53985,Q9Y5L0,Q9H2D1,Q9UJZ1,Q6N075,O43772,Q8N1F7,P52292,Q8NFH4,Q9C0E2,Q99595,Q9Y619,Q9UI26,O15397,O43615,O00410 17 +metalloprotease 0.3969980215621171 0.4492444207472583 0.6532553465414466 1.0 1.0 28 P55786,Q9NZ08 2 +translation factor 0.4159186578740035 0.4179081702832786 0.6760142586894009 1.0 1.0 7 Q06787 1 +acyltransferase 0.4114439896742553 0.377338541554964 0.7059220334341356 1.0 1.0 17 Q8NCC3,P50416,Q92696,Q6UWP7,P53611,Q92604,P23786,P35610 8 +RNA methyltransferase 0.4075521747320291 0.3667050108226917 0.7138390684750444 1.0 1.0 10 Q96FX7,Q08J23 2 +endoribonuclease 0.5049302958177633 0.3562268606653371 0.7216706777107038 1.0 1.0 3 O75792,Q9H9J2 2 +heterotrimeric G-protein 0.7012236573759247 0.3534595095445161 0.7237439788992339 1.0 1.0 2 Q8NHH9 1 +ATP synthase 0.3969234384559099 0.3457615270192602 0.7295219407966902 1.0 1.0 22 P00846,P21281 2 +actin binding motor protein 0.3874880725203534 0.3036472267068257 0.7613966675737758 1.0 1.0 8 Q12965 1 +serine protease 0.3912774223507708 0.303639180861147 0.7614027980040756 1.0 1.0 20 P42785,Q4J6C6 2 +non-motor microtubule binding protein 0.388613020249481 0.2831388807795279 0.7770703779580845 1.0 1.0 18 P46821,Q66K74,Q9BSJ2,Q9UH99,O43663,Q7Z460,O94901,Q9UN37,P78559,O75351 10 +Hsp90 family chaperone 0.3989795918367309 0.2448327156594415 0.806585961245379 1.0 1.0 4 P07900,P14625,P08238 3 +decarboxylase 0.646838885112174 0.2340746444023063 0.8149270300030325 1.0 1.0 2 Q9UG56 1 +oxidase 0.3577452496590229 0.1714093685384867 0.8639018887702499 1.0 1.0 14 Q8NB78,O75845,Q15800 3 +chaperone 0.28644845421768 0.1585670203772028 0.8740100139180358 1.0 1.0 69 Q8IXB1,Q13526,P78318,O75937,Q9Y3C6,Q96BP3,Q9UHV9,O95456,Q9Y680,Q7KZN9,P62942,Q9NVH1,Q96JJ7,O15260,Q9NWM8,P46379 16 +ubiquitin-protein ligase 0.258030251133868 0.0919008170148485 0.9267768423265365 1.0 1.0 54 Q15386,Q5TAQ9,P61088,Q92990,Q13042,Q96T88,Q9UJX3,Q9NT62,Q13620,P19474,Q7Z7E8,Q9Y263,Q9GZZ9,P61086 14 +transcription cofactor 0.3271125201809468 0.087365011960814 0.9303813794187128 1.0 1.0 13 Q9HCD5 1 +protein phosphatase 0.3230598300197005 0.058663771108242 0.9532199160852608 1.0 1.0 18 Q99956 1 +nucleotidyltransferase 0.2687074829932051 0.045354024145111 0.9638251266663622 1.0 1.0 4 Q8TCS8,P31153,Q8NFW8 3 +scaffold/adaptor protein 0.2709034082267366 0.0238854661192201 0.9809439673334288 1.0 1.0 72 O60271,Q92783,Q99627,Q96PV6,Q9Y679,P07602,Q96CX2,Q9UQ13,Q15404,O60749,O14641,Q5BKZ1,Q9UQB8,Q96RT1,Q96L92,O60664 16 +acetyltransferase 0.2903250674774322 0.0218892631319997 0.9825362895040048 1.0 1.0 11 O00330,Q14CX7 2 +glycosyltransferase 0.3030468830942892 0.0144573186865698 0.9884651304557716 1.0 1.0 17 Q8TCJ2,Q9NYU2 2 +membrane trafficking regulatory protein 0.2886980260029977 0.0016024345074299 0.998721442794003 1.0 1.0 14 Q9H270,Q8WTV0,Q15334 3 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..97897e3dae7bb2810e5a258729ae6a11052adb34 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin receptor superfamily", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMFR", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APOL2", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARID3B", "ARIH1", "ARL1", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATF7IP", "ATG3", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCLAF1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKN2AIP", "CEBPZ", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNP", "COA3", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DUS2", "DUSP12", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "EMC2", "EMG1", "ENO1", "ENY2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNTB", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GINS1", "GINS2", "GIPC1", "GLA", "GLB1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNAI3", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOT1", "GOT2", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISYNA1", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LENG8", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRRC40", "LRRC47", "LRRC59", "LSM2", "LSM4", "LSM6", "LSS", "LYAR", "LYPLA1", "LYPLA2", "LYRM7", "LZTFL1", "MACF1", "MAGED2", "MAN1A1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARK2", "MARS", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED21", "MED24", "METAP2", "METTL13", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMS19", "MOB4", "MOGS", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCDN", "NCEH1", "NCOA5", "ND1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NENF", "NF1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSGEP", "OTUB1", "OXA1L", "OXNAD1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PARG", "PARL", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C3", "PIK3R4", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PUM1", "PUM2", "PURA", "PURB", "PUS1", "PWP1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDX", "RECQL", "REEP4", "REEP5", "REL", "REPS1", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIOK1", "RIOK2", "RIPK1", "RNASEH2A", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAP130", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC33A1", "SLC35B2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC4A1AP", "SLC7A1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP2", "TAPBP", "TARBP1", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM38B", "TMEM87A", "TMOD3", "TMPO", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAP1", "TRAPPC4", "TRIM13", "TRIM21", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT10C", "TRMT1L", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TST", "TTK", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4B", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UFL1", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", 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0000000000000000000000000000000000000000..b631acbf43360c2f2264d6b2f52bdb2b29be754b --- /dev/null +++ b/pharos_dto/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4aa9a669ef468925bc4001e4708af2dd0412d11c90f7f6e52828bf0dca8d6948 +size 149088 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b0afa590510b82553ac49d7fe285642db697ee68 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:60763e79658788a6b161eabc2f8418e3ab35d0533b608bc8533d880f48341062 +size 154759 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ad6c43f8d7595dd4e434a9c39caff41ef4f12e5c --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +mRNA splicing factor 31 56 3.1166774662301133 0.0018290155765747 20.18446601941747 60.25 -0.0534479997211008 0.543839505368344 8.174667919166573 3.2318387263906065 1.3503022593676848 0.3639653466937346 1.0 0.1920773275443584 6.285893785971488e-07 2.1818549828996387e-10 +mRNA processing factor 33 71 2.372582902354908 0.0176641985717755 25.347087378640776 75.25485436893204 -0.2985441958276097 0.5602779604890878 10.316515944124484 3.6776154061944775 1.2913421409729118 0.3651678095317845 1.0 0.2752945686830158 1.523799532819889e-06 4.967642745109438e-09 +Dehydrogenase 8 52 2.209726178479156 0.0271241717715313 14.00485436893204 56.08009708737864 -0.4370363771193292 0.4692872079440394 7.431563212064344 3.4983896420583886 1.174195224675972 0.3512016895000671 7.631546446818042e-06 0.0003891202112685 0.0006341449532491 0.0496450716031089 +F-type ATPase 0 9 2.084509477733097 0.037113849020524 3.174757281553398 7.754854368932039 0.3978961134348252 0.300656405601223 2.006916121747128 0.8649601417133376 1.341428125637103 0.2766885427231999 0.0526645480715484 0.1027954944442906 0.2382253475836706 0.4236908718837023 +Tubulin 2 6 2.0837649840842003 0.0371815498916539 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 1.0 1.0 0.0703212183088513 0.0547354250806853 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..19334f78115541fcc55956a94f2788ce5493f93b --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 1919, + "title": "Average number of proteins per term", + "value": 3.108910891089109 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5fb529f17b900865a5efe9bbca624141ed46902d --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..413e4cad7ee9c8f4f2c0c00a5a2d8ef4cce7d35a --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,72 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +mRNA splicing factor 0.5762278734951787 3.1166774662301133 0.0018290155765747 0.9701954622657216 0.3973858121123944 56 Q12872,Q01844,Q09161,Q12874,Q92804,Q07955,Q96E39,O43719,Q13242,P62312,Q08170,P62995,P84103,Q8IWZ8,Q15637,P19338,Q13243,Q8WXF1,P38159,P98179,P35637,P23246,O43172,Q14011,Q96PU8,Q13247,Q9BWF3,O75934,Q96PK6,Q15459,Q9Y4C8 31 +mRNA processing factor 0.5183596541362538 2.372582902354908 0.0176641985717755 0.9999999999999986 0.3973858121123944 71 Q12872,Q01844,Q96I25,Q09161,Q12874,Q92804,Q07955,Q96E39,O43719,Q13242,P62312,Q96SI9,Q08170,P62995,P84103,Q8IWZ8,Q15637,P19338,Q13243,Q8WXF1,P38159,P98179,P35637,P23246,O43172,Q14011,Q96PU8,Q13247,Q9BWF3,O75934,Q96PK6,Q15459,Q9Y4C8 33 +Dehydrogenase 0.4728031294960163 2.2097261784791553 0.0271241717715313 1.0 0.3973858121123944 52 Q8N4Q0,Q9BY49,O94788,O95831,P30837,Q8N8N7,P49419,P03886 8 +Tubulin 0.7826484314400508 2.0837649840842003 0.0371815498916539 1.0 0.3973858121123944 6 P04350,Q13509 2 +Growth factor 0.8531078622522981 1.987557584765759 0.0468606412418717 1.0 0.3973858121123944 4 Q5JRA6 1 +Mitochondrial amino acid transporter subfamily 0.807897354295556 1.924174961441576 0.0543326564856827 1.0 0.3973858121123944 5 O43772 1 +Phosphatase inhibitor 0.744597417297062 1.9144602038076712 0.0555613793942377 1.0 0.3973858121123944 6 Q01105,Q99733 2 +Phospholipase 0.8129733682588177 1.8263474637902648 0.0677979400024724 1.0 0.4091328517759262 4 Q8N2A8 1 +Phosphatase modulator 0.7203773840684972 1.810257252472306 0.0702559028260272 1.0 0.4092981362676396 7 Q01105,Q99733 2 +Translation initiation factor 0.6680635527377022 1.7895430850485317 0.0735273951884361 1.0 0.4092981362676396 20 O75153,P55010,P23588,O75822,Q15056 5 +Damaged DNA-binding protein 0.8863632101233885 1.7441896755409516 0.0811260210396773 1.0 0.419624890499032 3 Q9NYH9 1 +Extracellular structure 0.6934759655281776 1.692044939612115 0.0906374054198528 1.0 0.4248531379884122 8 Q32P28 1 +Oxygenase 0.7644599210083823 1.6286554485702918 0.1033859790085307 1.0 0.4478503244184436 4 Q16850,Q14534 2 +DNA helicase 0.6716805205100568 1.6147312303494985 0.1063689113165318 1.0 0.4518962813625981 11 Q96S55,Q14566,P33991 3 +SLC superfamily of solute carriers 0.4160266966577823 1.3782822942846151 0.1681161476016093 1.0 0.531492097226063 41 Q6N075,O43772,Q70HW3,Q9HC07,Q96QD8,Q9BQT8 6 +F-type and V-type ATPases 0.606006178299363 1.3742500388190335 0.1693640709652997 1.0 0.5318113054343518 17 P00846,P21281 2 +TK group 0.6437316019702691 1.2265594244520246 0.2199882275390048 1.0 0.5774859761186644 5 Q05397 1 +Acyltransferase 0.5768048314586335 1.143077904234431 0.2530062473369692 1.0 0.614387926808521 10 Q92696,P53611,Q9Y679,P35610,P24386 5 +Translation factor 0.5098097489735371 1.113880641827298 0.2653303951740287 1.0 0.6331498880408564 27 O75153,P55010,P23588,O75822,Q15056 5 +Calcium-binding protein 0.536711547473339 1.0198103045818063 0.3078184351388024 1.0 0.6743191518622853 18 Q15293,Q14257,P43307,O43852 4 +Tight junction 0.6879198250708557 0.9811822138145024 0.3265028935313512 1.0 0.6879256459589121 3 Q9UDY2 1 +Cell-cell junction 0.6879198250708557 0.9811822138145024 0.3265028935313512 1.0 0.6879256459589121 3 Q9UDY2 1 +Other group 0.532951456842227 0.9363293833158284 0.3491036240164362 1.0 0.7061949904657494 12 O14920 1 +Chromodomain 0.6415545635318725 0.8078174618002513 0.4191956713778326 1.0 0.7771973358528084 3 P83916 1 +Intracellular calcium-sensing protein 0.5030976650077115 0.8064450808309545 0.4199862622612622 1.0 0.7771973358528084 15 Q15293,Q14257,O43852 3 +Calmodulin 0.5030976650077115 0.8064450808309545 0.4199862622612622 1.0 0.7771973358528084 15 Q15293,Q14257,O43852 3 +Epigenetic regulator 0.4519628024594857 0.7192534067841666 0.4719847984126744 1.0 0.8189143727716119 26 Q8NB78,Q13547,Q8WWQ0,Q9H7B4,Q96KQ7,P83916 6 +Receptor 0.4646554653194177 0.717770795067474 0.4728986235784558 1.0 0.8189143727716119 23 Q9BUN8,Q9UQB8,Q8WTV0 3 +V-type ATPase 0.4841883618170253 0.7035490779556938 0.4817136329043414 1.0 0.8222296675490317 8 P21281 1 +P-type ATPases 0.4734607271366212 0.651529622823216 0.5147046612363928 1.0 0.8456491822882172 9 P20020,P05026 2 +Oxidoreductase 0.3912310244553288 0.6420460235456446 0.520843300739616 1.0 0.8499135154075877 109 Q8N4Q0,Q9BY49,Q15392,Q16850,O94788,O95831,Q14534,P11310,P30837,P00403,Q8N8N7,P49419,O43169,O43837,O15260,P03886 16 +Bromodomain 0.4645335803564354 0.6272795361325596 0.5304760150767471 1.0 0.8549538909189399 6 O60885,Q8WWQ0,P25440 3 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.7946974847042841 0.6148295402709955 0.5386672985743006 1.0 0.8585569318638563 2 P08195 1 +KRAB box transcription factor 0.5713033237793624 0.5603761978784004 0.5752228633271805 1.0 0.8786287419628909 3 O95785 1 +C2H2 zinc finger transcription factor 0.5713033237793624 0.5603761978784004 0.5752228633271805 1.0 0.8786287419628909 3 O95785 1 +STE20 family 0.4461032625094916 0.5485060173814765 0.5833444986225309 1.0 0.8793700650876958 6 Q13043,Q9P289,Q13177 3 +Non-motor microtubule binding protein 0.4492662646682043 0.5424910498132434 0.5874802714951897 1.0 0.8800820706071225 15 P46821,Q66K74,Q9BSJ2,Q9UH99,O43663,O94901,Q9UN37,P78559,O75351 9 +Oxidase 0.4376321860535011 0.523603498790407 0.6005543474844133 1.0 0.8844040568607051 20 Q15800,P11310,O75845,O15260,O43169,P20674 6 +Chromatin/chromatin-binding protein 0.4415294147373218 0.5233863442893852 0.6007054251831982 1.0 0.8844040568607051 18 Q9UBU8,Q8WXI9 2 +Signaling 0.4406554905505898 0.5191211848032142 0.6036762360248669 1.0 0.8844040568607051 18 P43490,O00264,Q7Z4V5,Q8WUJ1,O14641,Q5JRA6 6 +DNA-directed DNA polymerase 0.4338863046917899 0.4978073765235051 0.6186198162189154 1.0 0.891491962771177 6 Q9NRG0 1 +Glycosyltransferase 0.4391733278620452 0.4955530808472937 0.6202097628471508 1.0 0.8915224980551928 15 Q8TCJ2,Q8N128,Q9NYU2 3 +G-protein 0.3990281692079252 0.4609243796716774 0.6448528598617147 1.0 0.8982676488897096 28 Q5TAQ9,Q16181,Q9UI26,P61586,O15397,Q8NHH9,P11233,O00429,Q14141 9 +Metalloprotease 0.3289297939465696 0.4408966226480402 0.6592878388149241 1.0 0.9088889099754592 39 P55786,Q9NZ08 2 +SNARE protein 0.4214853318554071 0.4331461071521949 0.6649086283601162 1.0 0.9113997555879022 8 O15400 1 +Nuclease 0.3618632521044357 0.4281290578203779 0.6685571622311419 1.0 0.9122561672306057 34 Q9UQ84,Q5JSZ5,Q5TA45 3 +Zinc finger transcription factor 0.430347552633634 0.3687104527320015 0.7123435567271508 1.0 0.9302142816712344 5 Q8WU90,O95785 2 +Helicase 0.4036190646919639 0.3675000488603889 0.713246055398342 1.0 0.9302142816712344 21 Q96S55,Q9BQ75,Q92620,Q14566,P33991 5 +Reader 0.4095506648786063 0.3672475626861968 0.7134343642381709 1.0 0.9302142816712344 12 Q8WWQ0,P83916,O60885,P45973,P25440 5 +Ion channel 0.4063310187656618 0.361926319150075 0.7174070915098905 1.0 0.9305024537318982 10 Q8NE86 1 +Heterotrimeric G-protein 0.7012236573759247 0.3534595095445161 0.7237439788992339 1.0 0.9308744607959988 2 Q8NHH9 1 +Ca2+-ATPases 0.4244420020019523 0.31322500755811 0.7541097203889962 1.0 0.9409877962297386 4 P20020 1 +Actin binding motor protein 0.3874880725203534 0.3036472267068257 0.7613966675737758 1.0 0.9409877962297386 8 Q12965 1 +CDK family 0.4082569688667921 0.2984257311071008 0.765378252679191 1.0 0.9409877962297386 5 P24941 1 +SLC25 family of mitochondrial transporters 0.3897472917618136 0.2969603477818175 0.7664967821573376 1.0 0.9409877962297386 20 O43772,Q9BQT8,Q70HW3 3 +Protein phosphatase 0.3837161608041753 0.2721803607079314 0.7854833418729843 1.0 0.9409877962297386 11 P30154,P10586 2 +Small GTPase 0.3740623702163453 0.2607882497554388 0.794255806318592 1.0 0.9409877962297386 24 Q16181,Q9UI26,P61586,O15397,P11233,O00429,Q14141 7 +Cytokine 0.6563562202583152 0.252929019632058 0.8003230639798922 1.0 0.9409877962297386 2 P43490 1 +Hsp90 family chaperone 0.3989795918367309 0.2448327156594415 0.806585961245379 1.0 0.9409877962297386 4 P07900,P14625,P08238 3 +DMPK family 0.6420802175390878 0.2249858730470443 0.821990264224054 1.0 0.9409877962297386 2 O75116 1 +ROCK subfamily 0.6420802175390878 0.2249858730470443 0.821990264224054 1.0 0.9409877962297386 2 O75116 1 +Microtubule family cytoskeletal protein 0.2875221939948348 0.1903629837103401 0.8490247019745403 1.0 0.9409877962297386 40 Q66K74,Q9BSJ2,Q9UH99,O95235,P04350,Q13509,Q9Y266,Q02241,Q9Y6G9,Q9BUF5,P78559 11 +Cu+-ATPases 0.589734874235221 0.1402147845357756 0.888490290931397 1.0 0.9409877962297386 2 Q04656 1 +Methyl-lysine/arginine binding protein 0.3426938060577562 0.1314714449242709 0.8954023741298411 1.0 0.9409877962297386 5 P83916 1 +mRNA polyadenylation factor 0.324029952348539 0.1284776750720431 0.8977709645066434 1.0 0.9409877962297386 6 Q96GM8,P51003,Q12996,Q10570,O95453 5 +DNA binding protein 0.2628748001276004 0.1269997409713504 0.8989406035646512 1.0 0.9409877962297386 54 Q13416,Q8WXI9,O60934,Q9NYH9,Q9UBU8,P17096,Q29RF7,Q13330,Q8WVM7 9 +Eraser 0.3209085307488464 0.1209863635459072 0.9037018361615512 1.0 0.9409877962297386 6 Q8NB78 1 +STE group 0.31925674223768 0.1006831696461266 0.9198019721515291 1.0 0.944339399600954 8 Q13043,Q9P289,Q13177 3 +TKL group 0.4490142760027281 0.0358972923349316 0.9713642548813364 1.0 0.9790168094103384 2 Q13546 1 +GSK family 0.3990482664853879 0.0269626217342541 0.9784895467199152 1.0 0.9841307338341284 2 P49840 1 +GSK subfamily 0.3990482664853879 0.0269626217342541 0.9784895467199152 1.0 0.9841307338341284 2 P49840 1 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ada192c46468663fbf334e9c46465596d7409d1e --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S14, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP synthase-coupling factor 6, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase WRNIP1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Activating signal cointegrator 1", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase family 16 member A1", "Aldehyde dehydrogenase, mitochondrial", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Arsenite methyltransferase", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 3", "CCR4-NOT transcription complex subunit 7", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit delta", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-3", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centromere/kinetochore protein zw10 homolog", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class II transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Copper-transporting ATPase 1", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine protease", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytokine receptor", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "DCK/DGK family", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication complex GINS protein PSF1", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidine kinase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase DTX3L", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase ZNF598", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FAK family", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Focal adhesion kinase 1", "Follistatin-related protein 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-mannose 4,6 dehydratase", "GHMP kinase family", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-tubulin complex component 2", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Geranylgeranyl transferase type-2 subunit beta", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SMYD3", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1-related protein", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin receptor superfamily", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF13B", "Kinesin-like protein KIF14", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lipoma-preferred partner", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAPK family", "MAPKAPK family", "MAPKAPK subfamily", "MARK subfamily", "MCU family", "MFS-type transporter SLC18B1", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Map kinase-activated protein kinase 2", "Mediator of RNA polymerase II transcription subunit 21", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloendopeptidase OMA1, mitochondrial", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Mevalonate kinase", "Mevalonate kinase subfamily", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Multidrug resistance protein 1", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light chain 6B", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurofibromin", "Neurolysin, mitochondrial", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "OCIA domain-containing protein 1", "OCIA domain-containing protein 2", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 6", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 3", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PDZ domain-containing protein GIPC1", "PEK family", "PH-interacting protein", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PITSLRE subfamily", "PKN family", "PLK family", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase catalytic subunit type 3", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Phosphoserine phosphatase", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein ABHD16A", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein NDRG1", "Protein NDRG3", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Proto-oncogene c-Rel", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Pumilio homolog 2", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIO family", "RIO1 subfamily", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab proteins geranylgeranyltransferase component A 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein nGAP", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 1", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC18 family of vesicular amine transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio1", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium-coupled neutral amino acid transporter 1", "Sodium-coupled neutral amino acid transporter 2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 2, facilitated glucose transporter member 8", "Solute carrier family 35 member F2", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-binding protein 3", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TTK family", "Tapasin", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcriptional activator protein Pur-alpha", "Transcriptional activator protein Pur-beta", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4A chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm6", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-Ie", "Unconventional myosin-VI", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 11 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuole membrane protein 1", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "WEE family", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger and BTB domain-containing protein 10", "Zinc finger protein 281", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 5", "Zinc transporter ZIP14", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "ANAPC1", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APOL2", "ARCN1", "ARFIP1", "ARFIP2", "ARHGDIA", "ARID3B", "ARIH1", "ARPC1A", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATIC", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCLAF1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRD2", "BRD4", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP3", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC37", "CDC42", "CDC45", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKN2AIP", "CEBPZ", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHM", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCK", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DTX3L", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "EMC2", "EMG1", "ENO1", "ENPP1", "EPHA7", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTB", "FOXRED1", "FSCN1", "FSTL1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GINS2", "GIPC1", "GLB1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNAI3", "GNPDA1", "GNS", "GOLGA2", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HEATR1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPP", "LRRC47", "LSM2", "LSM4", "LSM6", "MACF1", "MAGED2", "MAN1A1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARK2", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED21", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MIPEP", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL48", "MRPL9", "MRPS14", "MRPS16", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCBP1", "NCEH1", "NCL", "NCOA5", "ND1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS7", "NEDD4L", "NEK9", "NF1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCIAD2", "OCLN", "OCRL", "OLA1", "OMA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSGEP", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C3", "PIK3R4", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPT1", "POGZ", "POLDIP3", "POLR1A", "POLR1C", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKAG1", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PSPH", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPRF", "PUM1", "PUM2", "PURA", "PURB", "PUS1", "PWP1", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QSOX2", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RASAL2", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDX", "RECQL", "REEP4", "REEP5", "REL", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIOK1", "RIOK2", "RIPK1", "RNASEH2A", "RNH1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIRT2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SMYD3", "SNAP23", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TAP2", "TAPBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM38B", "TMEM97", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIP4", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TST", "TTK", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXNDC12", "TXNDC17", "TXNDC9", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4B", "UCHL5", "UGGT1", "UNC119", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP36", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP6", "VAMP7", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS11", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VRK1", "VRK2", "WARS", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR82", "WIZ", "WRNIP1", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM4", "ZNF281", "ZNF598", "ZW10", "ZYX"], "leading_proteins": ["ACADM", "AIFM1", "ALDH1A2", "ALDH1B1", "ALDH7A1", "ATL2", "ATP1B1", "ATP2B1", "ATP6", "ATP6V1B2", "ATP7A", "AUP1", "BAIAP2", "BCAS2", "BRD2", "BRD4", "CALU", "CBX1", "CBX5", "CDK2", "CHM", "CHRAC1", "CIRBP", "CLUH", "CMSS1", "COX2", "COX5A", "CPSF1", "CSTF3", "CYB5B", "CYB5D2", "CYP51A1", "DCAF8", "DERL1", "DHCR24", "DHX38", "DNM1L", "DVL2", "DYNC1LI1", "EHMT2", "EIF3J", "EIF4B", "EIF4H", "EIF5", "ERAP1", "EWSR1", "EXO1", "FAM177A1", "FUS", "GATAD2B", "GSK3A", "HDAC1", "HDGFL2", "HMGA1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HTATSF1", "IDH3B", "IKBKB", "INTS11", "IPO11", "IPO8", "KDM1B", "KIF20A", "KIF23", "LSM6", "MAP1A", "MAP1B", "MAP1S", "MCM4", "MCM6", "MCU", "MFSD5", "MIA3", "MORF4L1", "MSMO1", "MTA1", "MYO1E", "NAMPT", "NAP1L4", "NBN", "NCBP1", "NCL", "ND1", "NPEPPS", "NUDC", "ORC2", "P3H1", "PAK2", "PAPOLA", "PARN", "PDS5A", "PECR", "PGRMC1", "PHIP", "PLD6", "PPP2R1B", "PRC1", "PRPF4", "PRRC2B", "PSPC1", "PTGR2", "PTK2", "PTPRF", "QKI", "RABGGTA", "RABGGTB", "RALA", "RBM14", "RBM17", "RBM19", "RBM3", "RBM4", "RBMX", "RBMXL1", "RCN1", "RCN2", "RHOA", "RIPK1", "ROCK2", "SC5D", "SCARB1", "SEPT6", "SEPT7", "SET", "SF1", "SF3A1", "SF3A3", "SFPQ", "SFSWAP", "SLC25A20", "SLC25A21", "SLC25A26", "SLC38A2", "SLC3A2", "SMYD3", "SOAT1", "SQLE", "SRSF1", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF9", "SSR1", "STAG1", "STK26", "STK4", "STRBP", "STT3B", "STX7", "SUGP1", "SUN1", "SUN2", "SURF4", "TAF15", "TJP2", "TMEM165", "TOE1", "TRA2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "UGGT1", "UTP6", "VPS4A", "VPS4B", "WIZ", "WRNIP1", "ZADH2", "ZC3H15"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3108bc22a4c1658288854bb2b358b7a8822f3f40 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f86127cba8983d988a525ef7f2f6a705043926e6f22eb14ad0e96d078948faa6 +size 219700 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ddd662d46a4f8971ba47d18342352a728e89ddee --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..fc37f490e8f4b007b0432235381c5b9f993f8116 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e9f3391b8421037cadacb167fa17561390c4e4ff6cb2eabdf8bec36d3324b4f4 +size 127377 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..1c8994da053b564465814ec6415014d2c379dcf9 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cd9d6a765390af373063177edc1c38a5bf853491198d9f6aa467050964c90a55 +size 138066 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9f389c8c3183c49d88cee8133d7ecdaad892dae0 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94957aa3aa2421d1bc7fcad31b3a9782ea0062d699dd8394ffa7c246d2d27746 +size 73194 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3fdc83b860bdfbcb4d7db481857c574e3874abb9 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Tbio 471 2267 2.296090011863731 0.0216707352777536 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 0.7097245108839214 0.5084200543941844 0.0187298948799197 5.704507780418299e-06 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..155e02ba2ea5faf00d1950def4ca553fb4d4e4e5 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 735.75 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1de76bbef7f07fbfd9b4b5d47c8399292764e22f --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..45d499900ab064bfc9d9b2c7f632cce224883892 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.2144995939844008 2.296090011863731 0.0216707352777536 0.0839057040718103 0.0866829411110146 2267 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471 +Tclin 0.3372363607722544 0.4703052825871855 0.6381369238722359 0.9828534368658944 0.6624330828860101 80 Q99720,O43676,P04350,Q13509,P62942,O96000,P05026,P48735,P03886 9 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..04418e3d0b75e66f75828ea35c4c27523ee7aef5 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", 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"DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTX3L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENPP1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM210A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPATCH11", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPCAL4", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS10", "INTS11", "INTS12", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISYNA1", "ITGB1", "ITM2C", "ITPA", "ITPK1", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRPPRC", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LSM12", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LYAR", "LYPLA1", "LYPLA2", "LYRM7", "LZTFL1", "MACF1", "MAD2L1", "MAGED2", "MAN1A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED21", "MED24", "METAP2", "METTL13", "MFN2", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXNAD1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGT", "PIGU", "PIH1D1", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM2", "PUM3", "PURA", "PURB", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QRICH1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDX", "RECQL", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF114", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYVN1", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEDC1", "TELO2", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM126A", "TMEM126B", "TMEM161A", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT10C", "TRMT1L", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4B", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VKORC1L1", "VMP1", "VPS11", "VPS13A", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF598", "ZNF638", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "AARS2", "ABHD10", "ACADM", "ACBD3", "ACOX1", "ACP6", "ACSF3", "ADD1", "AIFM1", "ALDH1A2", "ALDH1B1", "ALDH7A1", "AMOT", "ANKRD17", "ANO10", "ANXA11", "ANXA4", "APBB1", "APC", "APOL2", "APOOL", "AQR", "ARMC10", "ASCC1", "ATG3", "ATL2", "ATP1B1", "ATP2B1", "ATP2B4", "ATP6", "ATP6V0A1", "ATP6V1E1", "AUP1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BASP1", "BCAS2", "BCAS3", "BCL10", "BCL2L13", "BCLAF1", "BICD2", "BRAT1", "C1QBP", "CALU", "CAMLG", "CAPRIN1", "CBX1", "CCDC6", "CCDC86", "CCT2", "CD2AP", "CD47", "CDC16", "CDK5RAP3", "CFDP1", "CHCHD3", "CHID1", "CHM", "CHMP3", "CIP2A", "CIRBP", "CKAP4", "CLASP1", "CLCC1", "CLU", "CLUH", "CNNM4", "CNOT3", "COLGALT1", "COPS4", "COPS8", "COPZ1", "COTL1", "COX15", "COX5A", "CREB1", "CTNND1", "CTPS1", "CTTN", "CUTA", "CYB5B", "DBT", "DCP1A", "DDRGK1", "DDX41", "DERL1", "DHCR24", "DHX38", "DIABLO", "DICER1", "DIEXF", "DIMT1", "DNA2", "DNAJC10", "DNAJC11", "DNAJC8", "DNM1L", "DST", "DTNBP1", "DUSP9", "DVL2", "DYNC1LI1", "EIF2D", "EIF3J", "EIF4B", "EIF4G3", "EIF5", "ELOA", "EMD", "ENSA", "ENY2", "ERBIN", "ERCC2", "ERGIC3", "ERP44", "ESS2", "EWSR1", "EXO1", "EXOC1", "FAF2", "FAH", "FAM3C", "FGFR1OP", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP7", "FMR1", "FN3KRP", "FUBP1", "FUS", "FXR1", "G3BP2", "GALNT1", "GATAD2B", "GDAP1", "GDPD1", "GINS4", "GLMN", "GOLGA2", "GOLGA5", "GOLGB1", "GOPC", "GRSF1", "GTF2F1", "GTF2F2", "HADH", "HAUS3", "HAUS4", "HDGFL2", "HGS", "HIF1AN", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMGA1", "HNRNPA3", "HNRNPAB", "HNRNPDL", "HNRNPK", "HNRNPR", "HTATSF1", "HYOU1", "IDH2", "IDH3B", "IGBP1", "IMMT", "INA", "INTS11", "IPO11", "IPO8", "IST1", "ITM2C", "KCTD12", "KDM1B", "KIAA0391", "KIF23", "KLC2", "KPNA2", "KTN1", "KYAT3", "LARP4", "LASP1", "LCLAT1", "LEMD3", "LLGL1", "LMNB2", "LNPK", "LUC7L", "MAD2L1", "MAN1A1", "MAP1A", "MAP1S", "MARCKS", "MARCKSL1", "MCM4", "MCM6", "MCU", "MCUR1", "MED21", "MIA3", "MIGA1", "MINPP1", "MOGS", "MORF4L1", "MOSPD2", "MRPL15", "MRPS30", "MSMO1", "MSTO1", "MTA1", "MTBP", "MTDH", "MTFP1", "MTX1", "MTX2", "MYH14", "MYO1E", "NAA25", "NADK2", "NAGLU", "NAP1L1", "NAP1L4", "NASP", "NBAS", "NBN", "NCBP1", "NCL", "NCOA5", "NCSTN", "ND1", "NDUFB10", "NDUFB3", "NELFCD", "NEMF", "NENF", "NOL8", "NRBP1", "NRDC", "NSFL1C", "NSUN2", "NTMT1", "NUB1", "NUCB2", "NUCKS1", "NUDC", "NUDT9", "NUFIP2", "NUP188", "NUP35", "NUP93", "OCIAD1", "OMA1", "ORC2", "OSBPL8", "P3H1", "P3H4", "P4HA2", "PABPN1", "PACSIN3", "PAFAH1B3", "PAIP1", "PARL", "PAWR", "PCBD1", "PCNP", "PCYOX1", "PDCL3", "PDHB", "PDHX", "PDS5A", "PECR", "PEX19", "PFDN2", "PFDN6", "PGRMC1", "PHF5A", "PHIP", "PIGG", "PIGK", "PLA2G15", "PLD6", "PLIN3", "POLE3", "POLR2E", "POLR2H", "POLR2L", "PON2", "PPHLN1", "PPIL1", "PPP1R7", "PPP2R1B", "PPWD1", "PRAF2", "PRCC", "PRPF40A", "PRRC2A", "PSAP", "PSMB4", "PSMB6", "PSMB7", "PSMD11", "PSMG1", "PSPC1", "PTGR2", "PTK7", "PURA", "QKI", "RAB10", "RAB18", "RAB21", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAD50", "RALA", "RAPGEF2", "RASAL2", "RBM10", "RBM14", "RBM17", "RBM19", "RBM3", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBP1", "RCN1", "RCN2", "RDX", "REEP5", "REPS1", "RFC2", "RFT1", "RHOA", "RINT1", "RMND1", "RNF114", "RNF20", "RNF40", "RPA2", "RPL31", "RPL35", "RSU1", "RTN2", "S100A13", "SC5D", "SEC16A", "SEC24A", "SEC63", "SEPT6", "SEPT7", "SET", "SF1", "SF3A1", "SF3A3", "SF3B2", "SHOC2", "SIGMAR1", "SKIV2L", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC30A5", "SLC38A2", "SLC39A14", "SLC3A2", "SLIRP", "SMARCC2", "SMC3", "SNX2", "SNX27", "SNX3", "SORBS3", "SPAG9", "SPART", "SPECC1L", "SPEN", "SPTBN1", "SPTBN2", "SRPRA", "SRSF1", "SRSF3", "SRSF4", "SRSF5", "SRSF9", "SSNA1", "SSR1", "STAG1", "STAM", "STAMBP", "STMN1", "STOM", "STOML2", "STT3B", "STX10", "STX7", "STXBP4", "SUB1", "SUGP1", "SUN1", "SUN2", "SUPT5H", "SURF4", "SYMPK", "SYVN1", "TAF15", "TBC1D15", "TCEA1", "THRAP3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM8B", "TIMM9", "TMEM165", "TMEM199", "TMEM33", "TMX1", "TMX3", "TNPO3", "TOR1AIP2", "TOX4", "TPD52", "TPM1", "TPR", "TRA2B", "TRIM21", "TSC22D3", "TSN", "TSPAN6", "TST", "TTC37", "TUBB3", "TUBB4A", "TXNDC12", "TXNDC9", "TXNL1", "UBA5", "UBAP2L", "UBE3C", "UGDH", "UGGT1", "USO1", "USP15", "USP19", "USP48", "UTP15", "UTP6", "VIM", "VPS11", "VPS26A", "VPS51", "VRK2", "VTA1", "WAPL", "WASHC5", "WBP11", "WIZ", "WRNIP1", "XPO4", "YBX1", "ZADH2", "ZC3H14", "ZC3H15", "ZNF318", "ZNF326", "ZPR1"]} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/idx2term.json 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-0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4232c1e7f81b68060a94a1043b9aa08f009faf99 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,44 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Sodium transport 0.7143849942980881 1.7780074542178157 0.0754026306237214 0.999997589052118 1.0 6 Q96QD8 1 +Sugar transport 0.8950790636658249 1.777348694235989 0.0755108865672595 0.999997635184698 1.0 3 P31751 1 +RNA-mediated gene silencing 0.6589353187883571 1.6549870473291022 0.0979271253448357 0.9999999588027788 1.0 17 Q9UIV1,Q9UPY3,Q9BWF3,O75175,Q06787 5 +Meiosis 0.6185979001791231 1.441390634949124 0.1494743545223249 0.9999999999974972 1.0 17 P24941,Q8N2A8,Q9UH99,Q92878,O60934,Q9UQ84,Q9UQE7,Q5VUA4 8 +Glycogen biosynthesis 0.6787912649927628 1.274455672470627 0.2025019727664985 1.0 1.0 4 P31751 1 +Glyoxylate bypass 0.9853840924541118 1.2666994555886066 0.205262774758528 1.0 1.0 2 P48735 1 +Ion transport 0.3790973790129922 1.145599025589667 0.2519611006425801 1.0 1.0 60 Q6N075,P20020,P00846,Q8TAD4,Q14847,Q93050,Q6P4Q7,Q96AQ8,Q8NE86,P21281,Q96QD8,Q96S66,P05026,P0CG08,P36543,P23634 16 +Phospholipid metabolism 0.5736802317278427 1.1325724018927543 0.257393863723387 1.0 1.0 11 Q9NPH0 1 +GPI-anchor biosynthesis 0.6051653711820808 1.0606824864708972 0.2888342217411779 1.0 1.0 5 Q92643 1 +Notch signaling pathway 0.5851020004745964 0.9749408452873308 0.3295896037595915 1.0 1.0 5 Q96T58 1 +Purine salvage 0.5818041439193811 0.9609085042702776 0.3365981744157409 1.0 1.0 5 P55263 1 +Complement pathway 0.8895309313392123 0.9274589413314585 0.3536883001874753 1.0 1.0 2 P10909 1 +Biomineralization 0.875254928619986 0.8784218811482931 0.37971481417995 1.0 1.0 2 P22413 1 +mRNA capping 0.6462531415516743 0.825116693105874 0.4093053433440139 1.0 1.0 3 Q09161 1 +Exocytosis 0.5106320350143285 0.8240010411136224 0.4099389663992365 1.0 1.0 11 P40222,P11233,Q5JRA6,Q9NV70,Q15334 5 +Electron transport 0.3353415112099062 0.8197047058813045 0.4123844666722931 1.0 1.0 43 O43396,O43676,P00403,O96000,O43169,P03886 6 +Adaptive immunity 0.4965795614213166 0.7618634242442096 0.4461415216933098 1.0 1.0 13 Q9NZ08,O95999,Q07021,P01889,P10321,P04439 6 +Lipid biosynthesis 0.3256331110461106 0.7434404933312809 0.4572150360720382 1.0 1.0 50 Q9BY49,Q15800,Q15392,Q6UWP7,Q16850,Q9H3P7,P48449 7 +Aromatic hydrocarbons catabolism 0.830047586675732 0.7272936555405384 0.4670460838617338 1.0 1.0 2 P34913 1 +Detoxification 0.830047586675732 0.7272936555405384 0.4670460838617338 1.0 1.0 2 P34913 1 +Zinc transport 0.8052345343303886 0.6477314224592158 0.5171586769710099 1.0 1.0 2 Q8TAD4 1 +Cell adhesion 0.417033124739937 0.6331064724318186 0.5266641158895702 1.0 1.0 30 Q13308,O60504,P10586,Q03001,P05026 5 +Immunity 0.3252889994748381 0.5150406802646814 0.6065245933069752 1.0 1.0 67 Q96S55,Q9NZ08,Q9BWS9,Q07021,P01889,Q9UQ84,P17812,O75179,P04439,P10909,Q96PK6,Q8WXF1 12 +Biological rhythms 0.3209442280644058 0.5094684363860538 0.6104239170948969 1.0 1.0 41 Q13547,P23246,P43490,O00429,Q9Y2W1,Q03164,Q9UNS1,Q06210,P16220,Q13330,Q8WXF1 11 +Translation regulation 0.3004320090290702 0.5087702181224579 0.6109132970245499 1.0 1.0 49 Q9Y5S9,Q9UIV1,O75175,Q06787,O43432,Q9H074,P31751 7 +Lipid transport 0.4323052162495505 0.5087144611355441 0.6109523844959655 1.0 1.0 21 Q99720,Q9UID3 2 +Steroid biosynthesis 0.4261491195251975 0.477473940199502 0.6330246733665112 1.0 1.0 21 Q15392,Q15800,Q16850,Q9H3P7,P48449 5 +Sensory transduction 0.4310597489242602 0.4721791710658783 0.6367989056406123 1.0 1.0 8 Q6P4Q7,Q96EV8,P24386,Q13432 4 +Neurogenesis 0.3069249847626658 0.4634832307446027 0.6430180321038905 1.0 1.0 42 Q8IUH3,Q06787,Q8TAQ2,P55209,Q16352,Q8WUJ1,Q9Y4G8,Q9Y263 8 +Growth regulation 0.4255945911102564 0.444127737335438 0.6569502336652915 1.0 1.0 9 Q9UBU8 1 +Calcium transport 0.4242171075059565 0.43848259126522 0.6610364871318866 1.0 1.0 9 P20020,Q96AQ8,Q8NE86 3 +Nonsense-mediated mRNA decay 0.4068329028834573 0.3595877502327286 0.719155445553088 1.0 1.0 11 Q9NPI6,Q9Y5S9,Q09161 3 +Cell shape 0.3911861879433589 0.3329806843074441 0.7391488636578494 1.0 1.0 6 P35580,Q7Z406,P35579 3 +Angiogenesis 0.3795422019246428 0.257310096704536 0.7969393987608699 1.0 1.0 11 Q9H2J4,Q05397,Q13685,Q9H6U6 4 +Vision 0.370370869722104 0.2527300329263779 0.800476838177635 1.0 1.0 7 Q6P4Q7,Q13432,P24386 3 +Hydrogen ion transport 0.3756330617285124 0.2494047022046101 0.803047748220429 1.0 1.0 22 P00846,P21281 2 +Respiratory chain 0.3461028837787043 0.2179903568166797 0.8274366249074685 1.0 1.0 30 P00403,O96000,P03886 3 +Tricarboxylic acid cycle 0.3633916039134386 0.1867099433507492 0.8518880595341118 1.0 1.0 19 O43837,O75874,P48735 3 +Innate immunity 0.2656184369540214 0.167794122874002 0.8667452462146128 1.0 1.0 52 Q96S55,Q15233,P01889,P12956,Q13283,P10321,O95801,Q9BWS9,P10909,O75179,P43243,Q8WXF1,Q07021,Q9UN86,O00743,P23246,O95999,Q9NUD5,P04439,Q96PK6 20 +Copper transport 0.589734874235221 0.1402147845357756 0.888490290931397 1.0 1.0 2 Q04656 1 +Spermatogenesis 0.3376673532131947 0.1061020144455015 0.9155014128731416 1.0 1.0 23 Q9Y508,Q8N2A8,Q96SI9,Q9P0K7,Q16181,Q08J23,Q14141 7 +mRNA transport 0.2635160476503844 0.0670171843592397 0.9465680228149372 1.0 1.0 61 Q9Y5S9,Q8N1F7,Q06787,Q8NFH5,Q5SRE5,Q09161,Q9NPA8,P84103,Q9UN86,Q96PU8,Q8TD16,Q07955,P12270 13 +Stress response 0.3043939551733239 0.0142249692059397 0.9886504994554062 1.0 1.0 27 Q86TM6,P98179 2 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0422b99dd6921b82e07cac2d7650902c142a55fc --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine metabolism", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP8L", "AKT2", "ALDH18A1", "ALDH3A2", "ALDOA", "ALDOC", "ALKBH5", "AMFR", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "API5", "APOL2", "APOO", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFIP2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARMC10", "ARMT1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATF7IP", "ATG3", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "AUP1", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "CACUL1", "CACYBP", "CAD", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CASP3", "CBL", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCNB1", "CD2AP", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CEBPZ", "CENPV", "CEP55", "CERS1", "CERS2", "CERS4", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHID1", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CLU", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPZ1", "COQ8A", "COQ9", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCP1A", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDB1", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC1", "DSC3", "DSG2", "DST", "DTNBP1", "DTX3L", "DUS2", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "EMC4", "EMG1", "EML4", "ENO1", "ENPP1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXK1", "FOXRED1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLRX", "GM2A", "GMPR2", "GMPS", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS3", "HAUS4", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "IST1", "ISYNA1", "ITGB1", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KCTD5", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF20A", "KIF23", "KIF2A", "KIF2C", "KIFBP", "KIFC1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "LAMC1", "LAMP1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LPP", "LRPPRC", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LYAR", "LYPLA1", "LYPLA2", "MACF1", "MAD2L1", "MAP1S", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED21", "MED24", "MFN2", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MMGT1", "MMS19", "MOB4", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MRE11", "MRI1", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NME1", "NME2", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NSA2", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGT", "PIGU", "PIH1D1", "PIK3C3", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMAIP1", "PMVK", "PNN", "PNP", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1C", "POLR1E", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "POP1", "PPAT", "PPHLN1", "PPID", "PPIF", "PPIH", "PPIL1", "PPM1F", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK2", "PTK7", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM2", "PURA", "PURB", "PUS1", "PWP1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QRICH1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANGRF", "RAPGEF2", "RARS", "RBBP5", "RBBP6", "RBM10", "RBM14", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPJ", "RCC1", "RCC2", "RCL1", "REEP4", "REL", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN3", "RMND1", "RNF114", "RNF20", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIGMAR1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORBS3", "SORT1", "SPATA5", "SPC24", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPTLC1", "SPTLC2", "SREK1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX6", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "SYVN1", "TACC3", "TACO1", "TAF6L", "TALDO1", "TAMM41", "TAP2", "TARDBP", "TARS", "TARS2", "TBCB", "TCAF1", "TCEA1", "TCERG1", "TDP2", "TDRKH", "TECR", "TFAM", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TK1", "TLE3", "TLN1", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM214", "TMEM38B", "TMX1", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOLLIP", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT1L", "TRMT6", "TRMT61A", "TROVE2", "TSFM", "TSG101", "TSNAX", "TSR1", "TTC19", "TTC26", "TTC4", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TXLNA", "TXNL1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4B", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UXT", "VAMP7", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS11", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WASHC5", "WBP11", "WDR12", "WDR33", "WDR36", "WDR43", "WDR45B", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "WRNIP1", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "ZBTB10", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "ACBD3", "ACP6", "ADK", "AKT2", "ANKRD17", "ATP1B1", "ATP2B1", "ATP2B4", "ATP6", "ATP6V0A1", "ATP6V1B2", "ATP6V1E1", "ATP7A", "BCAS3", "BCL10", "BICD2", "C1QBP", "CDK2", "CHID1", "CHM", "CLCC1", "CLU", "CNNM4", "CNOT3", "CNOT7", "COX2", "CREB1", "CTPS1", "CYB5B", "CYB5D2", "CYP51A1", "DCP1A", "DHCR24", "DICER1", "DNM1L", "DST", "DTNBP1", "EIF4G3", "ENPP1", "ENY2", "EPHX2", "ERAP1", "EXO1", "EXOC1", "FMR1", "G3BP1", "G3BP2", "GFPT1", "GPR89B", "HDAC1", "HLA-A", "HLA-B", "HLA-C", "IDH1", "IDH2", "IDH3B", "INA", "KMT2A", "LASP1", "LCLAT1", "LLGL1", "LSS", "MATR3", "MCU", "MCUR1", "MFSD5", "MIA3", "MORF4L1", "MSMO1", "MTA1", "MYH10", "MYH14", "MYH9", "NAMPT", "NAP1L1", "NBN", "NCBP1", "ND1", "NDUFB10", "NDUFB3", "NONO", "NSUN2", "NUP188", "NUP35", "NUP93", "PAIP1", "PDCL3", "PECR", "PIGK", "PLAA", "PLD6", "PPP6C", "PSPC1", "PTK2", "PTK7", "PTPRF", "QKI", "RAD50", "RAI14", "RALA", "RAPGEF2", "RBM14", "RBM3", "RBM4", "RBM45", "RBM8A", "RNF114", "SEPT6", "SEPT7", "SFPQ", "SIGMAR1", "SLC30A5", "SLC38A2", "SMARCC2", 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b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d7ada823ddbd03860bc5618d92640b4626ba822d --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 112, + "title": "Average number of proteins per term", + "value": 21.098214285714285 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..56dad7d382a518d5057ca68cf841dab37b20b3b5 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..78a53a11a68c25410eb6458535962ed6936c90ff --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,24 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Leber hereditary optic neuropathy 0.9904826648538398 1.285049186402876 0.1987750965406882 0.9999999999833852 1.0 2 P00846 1 +Microphthalmia 0.6518830617398019 1.261684779099452 0.2070622360364016 0.9999999999948146 1.0 5 Q5SRE5 1 +Retinitis pigmentosa 0.5835479224575489 1.221527043494105 0.2218865327187158 0.9999999999993736 1.0 15 Q92620,O43837,P00846,Q96S66 4 +Proto-oncogene 0.4504489120851583 1.2071770463997078 0.22736396820796 0.999999999999716 1.0 36 Q9H6U6,Q03164,Q01105,Q92804,P35637,Q92733,P31751 7 +Amyotrophic lateral sclerosis 0.5848821152922586 1.20424826292655 0.2284936369562635 0.999999999999759 1.0 13 Q99720 1 +Premature ovarian failure 0.896668932698844 0.9521697842051006 0.3410108823403219 1.0 1.0 2 Q06787 1 +Craniosynostosis 0.6766405984359157 0.938529579287616 0.3479723233068519 1.0 1.0 3 P16435,Q9ULC3 2 +Dystonia 0.5324179762900499 0.9296058205084672 0.3525752127028676 1.0 1.0 7 P04350 1 +Cataract 0.4887861604553149 0.8560976873994779 0.3919437477181633 1.0 1.0 23 Q15800,P08670,Q9H2M9,Q5SRE5,P48449 5 +Osteogenesis imperfecta 0.4889596930072843 0.7295242876222422 0.4656810165703846 1.0 1.0 7 Q32P28 1 +Cone-rod dystrophy 0.8259687287559487 0.7140286395186357 0.475209470189458 1.0 1.0 2 Q6P4Q7 1 +Congenital disorder of glycosylation 0.4741180003893114 0.6771013052583152 0.4983416808178817 1.0 1.0 17 Q96AA3,Q8N511,Q9HC07 3 +Diabetes mellitus 0.4676759099368013 0.6230216595142587 0.5332702885695646 1.0 1.0 13 P03886 1 +Neuropathy 0.2938604678492535 0.446552385675089 0.6551982808415073 1.0 1.0 49 O95831,P00846,Q03001 3 +Congenital myasthenic syndrome 0.5266352300521793 0.4188314307775183 0.6753393324611947 1.0 1.0 3 Q4J6C6 1 +Ectodermal dysplasia 0.4418367391972438 0.407582422607444 0.6835802711423813 1.0 1.0 5 O60716 1 +Cushing syndrome 0.6492182188987137 0.2387039639422585 0.8113351428188242 1.0 1.0 2 P10644 1 +Williams-Beuren syndrome 0.3484179734412133 0.1848252459401539 0.8533661055973714 1.0 1.0 7 Q15056 1 +Dwarfism 0.2896484257603001 0.1243162192282541 0.90106490583092 1.0 1.0 38 A2RRP1,O95831,P51530,P18074,Q32P28 5 +Aicardi-Goutieres syndrome 0.5271923861318915 0.0744811658890035 0.9406275269801574 1.0 1.0 2 P55265 1 +Deafness 0.2417701149485632 0.0612891850179424 0.951128903716372 1.0 1.0 45 O95831,Q9NR28,P21281,P18074,Q7Z406,Q9NWM8 6 +FDA approved drug targets 0.331421914792657 0.05306966313146 0.9576764026922516 1.0 1.0 119 Q99720,P20020,Q16836,Q16850,O14920,O75874,Q14534,Q13509,P23786,Q9NRF9,P62942,P49721,P48735,Q96QD8,P09525,P35610,P03886 17 +Hereditary spastic paraplegia 0.3046298323235718 0.0310357035818952 0.975241066037814 1.0 1.0 14 Q12768,O75298 2 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..748941aef3b1f17362b9a30b068b9a4d124ef4cc --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Phenylketonuria", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABCB1", "ABCB7", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKR1B1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APOL2", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASCC1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7A", "ATP7B", "ATXN10", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCL10", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLMH", "BLVRB", "BMS1", "BPTF", "BRAT1", "BRD4", "BUB1B", "BUD23", "C19orf70", "C1QBP", "CAD", "CALM3", "CALR", "CAMK2G", "CAMLG", "CANX", "CAPN1", "CARM1", "CARS", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNB1", "CCT5", "CD320", "CDC16", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDKAL1", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHM", "CHMP1A", "CHMP2B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CLU", "CNNM4", "CNOT1", "CNOT3", "COA3", "COA7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREB1", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBN1", "DBT", "DCAF8", "DCK", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DTNBP1", "DYNC1H1", "DYNC1I2", "DYNC2H1", "EARS2", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENPP1", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERC1", "ERCC2", "ERGIC1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOSC2", "EXOSC3", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTB", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GIGYF2", "GINS1", "GIPC1", "GLA", "GLB1", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNAI3", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GRB2", "GSDME", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", 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"NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEK9", "NF1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NSD2", "NSDHL", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OMA1", "OPA1", "ORC6", "OSGEP", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGT", "PIGU", "PIN1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", 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"RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "RTN2", "SAR1B", "SARS", "SART1", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC31A", "SEC61A1", "SEC63", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SHOC2", "SIGMAR1", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC33A1", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SMARCA4", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMYD3", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", 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sha256:fe26b38f591d5757f178744632bbfadf448387a6d033d78377c521296fc07d84 +size 147008 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e1b66dfabbd43bee7375a30dea18c0acc54accb7 --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:070cb387169cdfc1fa8fcabf9071098231f3cbc96890027c3cadf41b9565cb17 +size 67403 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..76ea8a7aa1f99f76cb78d7065b202f89e25de271 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 96, + "title": "Average number of proteins per term", + "value": 36.09375 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ea04265d0de302f227a33d3b7202251428db3fd6 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c7413d18ad77b523a49147a9d815bb8555778fdc --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,27 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Actin capping 0.6972263646215354 1.699767472241501 0.0891746722048962 0.9998724238530786 0.6759118881965419 6 Q01082,Q13813,P35241,O15020 4 +Methyltransferase 0.5120231451411834 1.6928353497996618 0.0904868119566142 0.9998889127864417 0.6759118881965419 36 Q8N6R0,Q9H7B4,O60725,Q96FX7,Q03164,Q9BV86,Q08J23 7 +Threonine protease 0.8333900034002097 1.5412548031870463 0.1232547841956579 0.9999967202038428 0.6759118881965419 3 P28074,P28072 2 +Muscle protein 0.64293106677465 1.4506081419384065 0.1468890068293347 0.9999997620248128 0.7050672327808065 7 Q03001 1 +Aminopeptidase 0.6141401828963895 1.341449033987011 0.1797747065625499 0.9999999945350886 0.8179503139033268 12 P55786 1 +Receptor 0.4711450920682167 1.2931266401005104 0.1959672627060054 0.9999999991941052 0.8179503139033268 35 Q99720,Q13308,P10586,P55899,Q8WTV0 5 +Dioxygenase 0.5787371578718488 1.164398089440822 0.24426272150427 0.9999999999978934 0.9082014814042142 12 Q9NWT6,P13674,O15460,Q32P28 4 +Endonuclease 0.5659898249644617 1.160190547724258 0.2459712345469746 0.9999999999983048 0.9082014814042142 17 Q8N2A8,Q9UQ84,Q9UPY3,P51530 4 +Nuclease 0.4599134807778645 1.073907085158624 0.2828643274923892 0.9999999999999862 0.9354188490736762 33 Q8N2A8,Q9UIV1,Q9BQ61,Q9UQ84,O15091,Q9UPY3,P51530 7 +Repressor 0.4246641808162602 1.0592517493356697 0.2894851429357481 0.9999999999999944 0.9354188490736762 101 Q01844,Q9NYF8,O75175,Q13242,P61978,Q9UIV1,O14979,Q08170,P62995,Q9GZT3,Q15637,Q06787,Q8WXF1,P67809,Q8NB78,P38159,Q8WXI9,Q5VUA4,P49750,Q96T58,Q9HCD5,Q14011,Q96PK6 23 +Exonuclease 0.5321990760040125 0.9954331060196248 0.3195256638032298 1.0 0.9354188490736762 18 Q9UQ84,Q9UIV1 2 +Serine protease 0.5028959776377623 0.7862154381386334 0.4317412831206688 1.0 1.0 10 Q4J6C6 1 +Prenyltransferase 0.6093165589935448 0.6913326044569347 0.4893565467045599 1.0 1.0 3 Q92696,P53611 2 +Monooxygenase 0.6054868680663578 0.6777898832067156 0.4979049264732218 1.0 1.0 3 Q16850 1 +Activator 0.360343077378947 0.5565340877184973 0.5778457982420135 1.0 1.0 91 Q9NPA8,O43719,Q14527,P61978,Q9UPP1,O14979,P61457,P62995,P53999,O00267,Q06787,Q8WXF1,P67809,P38159,Q9Y2W1,Q5VUA4,P16220,O00213,Q96T58,P42224,Q7RTV0,Q13503,Q9HCD5,Q5BKZ1,Q9BWF3,Q14011,Q13330,Q00577 28 +DNA-directed DNA polymerase 0.4925368538887626 0.5336790286027011 0.593563620879608 1.0 1.0 4 Q9NRG0 1 +Initiation factor 0.3740441978101432 0.5102307773700341 0.6098897924336457 1.0 1.0 34 P55010,P41214,P23588,O75822,Q15056 5 +Rotamase 0.4329045451665428 0.4998346263080962 0.6171915269515542 1.0 1.0 20 Q96BP3,Q96AY3,Q9Y680,P62942,Q9NWM8 5 +Metalloprotease 0.4036111719012079 0.4875292226127182 0.6258833390573351 1.0 1.0 28 P55786,Q9NZ08 2 +Ion channel 0.4110484233344261 0.3763759438714113 0.7066374274585177 1.0 1.0 11 Q8NE86 1 +Developmental protein 0.3207629193818251 0.3349931450628595 0.7376302572193556 1.0 1.0 79 Q9Y508,Q8IUH3,Q9UEE9,O75175,Q96SI9,P51114,Q9C0E8,Q92520,Q9NP72,O14641,Q9Y4G8,Q8NB78,Q9ULC3,Q13685,Q9UNS1,P31751,Q68CQ4,Q6UWP7,Q96PU8,Q16352,Q05397,Q9Y263,Q9Y4C8 23 +Protease 0.3186109617686103 0.2953405756508597 0.7677337232598189 1.0 1.0 81 Q9NZ08,Q9H300,P42785,P55786,Q92643,O94966,Q4J6C6 7 +GTPase activation 0.38281563781286 0.2902863198925502 0.77159720363732 1.0 1.0 23 Q9H2M9,Q8TC07,O60343,Q15042,Q9UJF2,Q9Y4G8,P52565,P24386,Q66K14 9 +Calmodulin-binding 0.3362829698665138 0.2368414060936599 0.8127798278359133 1.0 1.0 33 P20020,Q01844,Q01082,Q12965,P49006,Q7Z406,P35611,P23634 8 +Tyrosine-protein kinase 0.3403599713961618 0.1465759901849647 0.8834667060215904 1.0 1.0 9 Q15375,P33981,P41240,Q05397 4 +tRNA-binding 0.3211938655240408 0.0728146701073298 0.9419535968888568 1.0 1.0 13 Q08J23 1 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5a4a7dddb7e30e3adcd4ec422b9c376c97ff1dc3 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "AMFR", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APBB1", "APEH", "APEX1", "APRT", "AQR", "ARFGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATF7IP", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "CAD", "CALD1", "CALR", "CAMK1", "CAMK2D", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP3", "CAST", "CBL", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC37", "CDC42", "CDC5L", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2AIP", "CEBPZ", "CEP55", "CERS1", "CERS2", "CERS4", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHM", "CHMP1A", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLU", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF7", "DCD", "DCK", "DCP1A", "DCPS", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTX3L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "EMD", "EMG1", "ENDOD1", "ENO1", "ENPP1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC6L", "ERMP1", "ERO1A", "ERP44", "ESD", "ESPL1", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGH", "GLA", "GLB1", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNAI3", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPD2", "GPHN", "GPI", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPDH2", "INA", "INF2", "INTS11", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISYNA1", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD3", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRPPRC", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LYAR", "LYPLA1", "LYPLA2", "LYRM7", "MACF1", "MAGED2", "MAN1A1", "MAN2B1", "MAP1S", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED21", "MED24", "METAP2", "METTL13", "MFN2", "MGEA5", "MGME1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL48", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCEH1", "NCL", "NCOA5", "ND1", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NF1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "ORC6", "OSGEP", "OTUB1", "OTULIN", "OXNAD1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM7", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PIGG", "PIGK", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLS1", "PLS3", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR2B", "POLR2G", "POLR2H", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM2", "PUM3", "PURA", "PURB", "PUS1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RDH11", "RDH13", "RDX", "RECQL", "REL", "RETSAT", "REXO2", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK1", "RIOK2", "RIPK1", "RNASEH2A", "RNF114", "RNF20", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAP130", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3B1", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SIGMAR1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "SSU72", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "SYVN1", "TACO1", "TAF15", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDP2", "TDRKH", "TECR", "TFAM", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TMCO1", "TMEM109", "TMEM126B", "TMEM38B", "TMOD3", "TMPPE", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP12", "TRIR", "TRMT10C", "TRMT1L", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSN", "TSNAX", "TST", "TTK", "TTYH3", "TUFM", "TWF1", "TXNDC12", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4B", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTRN", "UXT", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VPS4A", "VPS4B", "VRK1", "VRK2", "WARS", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WRNIP1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "ZADH2", "ZBTB10", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZCRB1", "ZDHHC13", "ZFR", "ZMPSTE24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF638", "ZNF830", "ZRANB2"], "leading_proteins": ["AAMP", "ADD1", "AKT2", "APBB1", "ARHGDIA", "ATP2B1", "ATP2B4", "BCLAF1", "CFDP1", "CHM", "CHRAC1", "CIRBP", "CNOT3", "CNOT7", "CREB1", "CSK", "CYP51A1", "DICER1", "DIEXF", "DNA2", "DST", "DVL2", "EIF2D", "EIF3J", "EIF4B", "EIF4H", "EIF5", "ENY2", "EPHA7", "ERAP1", "EWSR1", "EXO1", "FAM3C", "FCGRT", "FKBP10", "FKBP14", "FKBP1A", "FKBP7", "FMR1", "FXR1", "GATAD2B", "HIF1AN", "HLTF", "HNRNPDL", "HNRNPK", "HTATSF1", "ICMT", "INA", "KDM1B", "KIAA0391", "KMT2A", "LCLAT1", "LNPK", "MARCKSL1", "MCU", "MED21", "METTL13", "MTA1", "MYH14", "MYO1E", "NCOA5", "NPEPPS", "NSUN2", "NTMT1", "P3H1", "P4HA1", "P4HA2", "PARL", "PCBD1", "PHF5A", "PHF8", "PIGK", "PLAA", "PLD6", "PPWD1", "PRCP", "PREPL", "PSMB5", "PSMB6", "PSPC1", "PTK2", "PTK7", "PTPRF", "PURA", "QKI", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RABGGTA", "RABGGTB", "RAPGEF2", "RASAL2", "RBM14", "RBM19", "RBM4", "RBM45", "RBMX", "RDX", "RNF114", "SCARB1", "SF1", "SIGMAR1", "SLIRP", "SMYD3", "SPEN", "SPTAN1", "SPTBN1", "SPTBN2", "SRSF4", "SRSF9", "STAT1", "STRBP", "SUB1", "SUPT5H", "TBC1D15", "TBC1D4", "TBC1D9B", "THRAP3", "TIMELESS", "TRA2B", "TRIR", "TRMT61A", "TTK", "USP19", "YBX1", "YLPM1", "ZNF318", "ZNF326"]} \ No newline at end of file diff --git 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sha256:b0ee269be61a2f9d5f65f03689ab5c54301d3ba84ffb0efd8272060626567886 +size 151137 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3d9c7dd5b6400e2f2deee9f7e3672dc531bd72a2 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:903d267a847e9a8c5011268147dae57f13db355d4fcd708527fe1d176de70899 +size 74673 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b21db103c5a2db413b416abfbd791b99899897bf --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Predicted intracellular proteins 523 2722 3.2232206158164023 0.0012675788496756 1052.9126213592233 2930.233009708738 -5.248196350890207 0.108353777008802 367.4824441165934 294.4528727150831 7.24167812525605 0.3049463326237019 0.8652044774886228 0.6735985412885503 0.8023632254069643 0.1608442185985165 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4f06bede9722febf81cf5239a056d32d1decc9e3 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 478.35 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..87db03506eaf32947043d7ed436efd813bfcd21c --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ded8baf04e5b503899a32d99f78c53b5836aa390 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,8 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted intracellular proteins 0.1778848909858193 3.2232206158164023 0.0012675788496756 0.0250486026960069 0.0253515769935131 2722 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523 +Predicted secreted proteins 0.4281908796077779 1.8432270221536389 0.0652958710957261 0.7408905679401521 0.652958710957261 47 Q13308,P22413,Q9NZ08,Q15165,P84157,Q07021,Q8WUJ1,Q92520,O60888,P10909,P80303,Q8N128,Q9UMX5 13 +Transcription factors 0.3945349326859829 1.4684165088147372 0.1419911199482826 0.9532441826989708 0.9142534077414944 49 P42224,P23246,Q8WXI9,Q96KC8,Q8TAQ2,O95785,Q00577,Q99576,Q03164,Q9Y2X9,Q7RTV0,Q8IVW6,P17096,O94842,P16220,Q13330,Q8WXF1,P67809 18 +Candidate cardiovascular disease genes 0.5334374235858581 0.9314436183534324 0.351624136857928 0.9998276001899356 0.9142534077414944 9 P10909,Q15165 2 +RAS pathway related proteins 0.4418615143558044 0.6334012427878358 0.5264716536415901 0.9999996786934068 1.0 25 O14920,Q13177,Q13043,P61586,Q9UQ13,P21359,Q9UJF2,P62993,P11233,P31751 10 +Disease related genes 0.2092665624224236 0.1282584293862729 0.8979444618731804 1.0 1.0 958 Q99720,Q8N201,Q13432,Q4G176,Q5TAQ9,P00846,Q6PGP7,O43772,Q8TAQ2,Q03164,Q9Y4L1,P48449,Q13126,O95630,P31483,Q9HC07,P48735,Q06210,Q9BUK6,P10321,P12270,P13807,P09601,P03886,P36543,O00330,Q15392,P98175,P61457,Q8N1F7,O95684,Q8NFH4,O14920,O75874,O95831,Q9H270,Q03001,Q9C0E8,Q6NUQ1,Q9H0B6,P40855,Q15067,Q92733,P25054,P16930,P42766,Q07864,Q9NWM8,Q15043,Q86TM6,Q8NBJ5,Q8N511,Q8NC56,Q8WXI9,P10586,O75298,Q5SRE5,Q70HW3,Q92643,Q8TD16,P00403,P35637,Q32P28,P31751,Q4J6C6,Q8WWQ0,P04350,P23786,Q6PJG6,Q15056,Q96AA3,P49419,Q8WVM7,Q05397,Q8N6R0,P28070,A2RRP1,Q9H6U6,Q9H2M9,Q6UN15,Q96D71,P07602,Q92804,O15460,Q9UQ13,Q96S66,P54802,P61978,Q92990,O43676,O60934,P55263,Q9HD26,Q06787,Q8TCJ2,P38159,P78318,Q13724,Q12965,Q96AY3,Q8NC96,P11310,Q01105,Q9UPY3,O43837,Q9BQT8,Q15800,P09493,P08670,Q13509,Q9Y619,Q9UJV9,P51530,P04439,Q9Y263,Q8N9N2,Q9Y5S9,Q16836,Q01844,P01889,Q12768,Q9Y2U8,Q9UID3,Q9NR28,Q8TBA6,Q15042,P17812,O75845,O75175,O60701,Q8N0X7,Q08J23,Q9NW15,Q15477,O14979,P51114,Q5JTZ9,P21281,P18074,Q7Z406,Q9Y4G8,Q96HY6,Q5H8A4,Q07021,Q5THJ4,Q92620,Q4G0N4,P50995,Q9GZZ9,Q86U42,P22413,P11177,O95999,O43172,Q9NWS8,Q7KZN9,Q6P4Q7,P33991,P35250,P35241,Q9UNW1,Q92542,Q03252,P50402,P20674,Q96EV8,Q9Y5L0,Q9UPP1,Q9H2D1,Q9BSJ2,Q92878,Q16204,Q9NPL8,Q9NP72,Q9BUF5,Q6PJT7,Q13951,Q9ULC3,Q9UQE7,O15020,O60885,P11182,O60716,O00429,Q8IUX1,Q69YQ0,Q5MNZ6,P07099,P17096,P23193,O60493,Q00577 192 +FDA approved drug targets 0.331421914792657 0.05306966313146 0.9576764026922516 1.0 1.0 119 Q99720,P20020,Q16836,Q16850,O14920,O75874,Q14534,Q13509,P23786,Q9NRF9,P62942,P49721,P48735,Q96QD8,P09525,P35610,P03886 17 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cc6c2e7b8d2b0292ca35ab1f024579168bc70fb2 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATF7IP", "ATG3", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C11orf98", "C12orf73", "C19orf53", "C19orf70", "C1QBP", "C1orf122", "C1orf35", "C1orf50", "C20orf27", "C2CD2", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC167", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDV3", "CEBPZ", "CENPI", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CERS4", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTX3L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENPP1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EZR", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM210A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPATCH11", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPCAL4", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS10", "INTS11", "INTS12", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISYNA1", "ITGB1", "ITM2C", "ITPA", "ITPK1", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRPPRC", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LSM12", "LSM2", "LSM4", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LYAR", "LYPLA1", "LYPLA2", "LYRM7", "LZTFL1", "MACF1", "MAD2L1", "MAGED2", "MAN1A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED21", "MED24", "METAP2", "METTL13", "MFN2", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL48", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS17", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXNAD1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGT", "PIGU", "PIH1D1", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM2", "PUM3", "PURA", "PURB", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QRICH1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB33B", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RASAL2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDX", "RECQL", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF114", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYVN1", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEDC1", "TELO2", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM126A", "TMEM126B", "TMEM161A", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT10C", "TRMT1L", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4B", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VKORC1L1", "VMP1", "VPS11", "VPS13A", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF638", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "ABHD10", "ACADM", "ACBD3", "ACOX1", "ACP6", "ACSF3", "ADD1", "ADK", "AIFM1", "AKT2", "ALDH1A2", "ALDH1B1", "ALDH7A1", "AMOT", "ANKRD17", "ANO10", "ANXA11", "ANXA4", "APC", "APOL2", "APOOL", "AQR", "ARID3B", "ARMC10", "ASCC1", "ATG3", "ATL2", "ATP1B1", "ATP2B1", "ATP2B4", "ATP6", "ATP6V0A1", "ATP6V1B2", "ATP6V1E1", "BAG4", "BAG5", "BAG6", "BAIAP2", "BASP1", "BCAS2", "BCAS3", "BCL10", "BCL2L13", "BCLAF1", "BICD2", "BRAT1", "BRD4", "C11orf98", "C1QBP", "CALU", "CAMLG", "CBFB", "CBX1", "CCDC6", "CCDC86", "CCT2", "CD47", "CDC16", "CDK2", "CDK5RAP3", "CEP44", "CFDP1", "CHID1", "CHRAC1", "CIP2A", "CIRBP", "CKAP4", "CLASP1", "CLCC1", "CLU", "CLUH", "CNNM4", "CNOT3", "CNOT7", "COLGALT1", "COPS4", "COPZ1", "COTL1", "COX15", "COX2", "COX5A", "CPT2", "CREB1", "CTDSPL2", "CTNND1", "CTPS1", "CUTA", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DBT", "DCAF8", "DCP1A", "DCTN3", "DCTPP1", "DCUN1D4", "DDRGK1", "DDX41", "DHCR24", "DHX38", "DIABLO", "DICER1", "DIEXF", "DIMT1", "DNA2", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC8", "DNM1L", "DST", "DTNBP1", "DUSP9", "DVL2", "DYNC1LI1", "EHMT2", "EIF2D", "EIF3J", "EIF4B", "EIF4G3", "EIF4H", "EIF5", "ELOA", "EMD", "ENPP1", "ENSA", "ENY2", "EPHX1", "EPHX2", "ERAP1", "ERBIN", "ERCC2", "ERGIC3", "ERP44", "ESF1", "ESS2", "EWSR1", "EXO1", "EXOC1", "FAF2", "FAH", "FAM129B", "FAM177A1", "FAM3C", "FAM49B", "FAM50A", "FCGRT", "FGFR1OP", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP7", "FMR1", "FN3KRP", "FUBP1", "FUS", "FXR1", "G3BP2", "GAK", "GALNT1", "GATAD2B", "GFPT1", "GINS4", "GLMN", "GOLGA2", "GOLGA5", "GOLGB1", "GOPC", "GRB2", "GRSF1", "GTF2F1", "GTF2F2", "GYS1", "HADH", "HAUS3", "HAUS4", "HDAC1", "HDGFL2", "HGS", "HIF1AN", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMGA1", "HMOX1", "HMOX2", "HNRNPA3", "HNRNPAB", "HNRNPDL", "HNRNPK", "HNRNPR", "HTATSF1", "HYOU1", "IDH1", "IDH2", "IDH3B", "IGBP1", "IKBIP", "IKBKB", "IMMT", "IMP4", "INA", "INTS1", "INTS11", "IPO11", "IRGQ", "ISOC1", "IST1", "ITM2C", "KCTD12", "KDM1B", "KIAA0391", "KIF20A", "KIF23", "KLC2", "KMT2A", "KPNA2", "KTN1", "LARP4", "LASP1", "LEMD2", "LEMD3", "LENG8", "LLGL1", "LMNB2", "LNPK", "LSM6", "LSS", "LUC7L", "MAD2L1", "MAP1A", "MAP1S", "MARCKS", "MARCKSL1", "MCM4", "MCM6", "MCU", "MCUR1", "MED21", "METTL13", "MINPP1", "MOGS", "MORF4L1", "MOSPD2", "MRPL11", "MRPL15", "MRPL16", "MRPL55", "MRPS26", "MRPS30", "MRPS35", "MRPS9", "MSMO1", "MSTO1", "MTA1", "MTAP", "MTBP", "MTDH", "MTFP1", "MTX2", "MXRA7", "MYH14", "MYO1E", "NAA25", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NASP", "NBAS", "NBN", "NCBP1", "NCL", "NCOA5", "NCSTN", "ND1", "NDUFA5", "NDUFB10", "NDUFB3", "NECAP1", "NELFCD", "NEMF", "NENF", "NF1", "NOL8", "NPEPPS", "NRBP1", "NRDC", "NSUN2", "NTMT1", "NUB1", "NUCB2", "NUCKS1", "NUDC", "NUDT9", "NUFIP2", "NUP188", "NUP35", "NUP37", "NUP93", "OCIAD1", "ORC2", "OSBPL8", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPN1", "PACSIN3", "PAFAH1B3", "PAIP1", "PAK2", "PARL", "PAWR", "PBDC1", "PCBD1", "PCNP", "PCYOX1", "PDCL3", "PDHB", "PDHX", "PDS5A", "PDXDC1", "PECR", "PEX19", "PFDN2", "PFDN6", "PHF5A", "PHF8", "PHIP", "PIGG", "PIGK", "PIN1", "PITRM1", "PLA2G15", "PLAA", "PLIN3", "POLE", "POLE3", "POLR2H", "PON2", "PPHLN1", "PPIL1", "PPP1R7", "PPP2R1B", "PPP2R2A", "PPWD1", "PRCC", "PRCP", "PREPL", "PRPF4", "PRRC2A", "PSAP", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PSMG1", "PSPC1", "PTGR2", "PTK2", "PTK7", "PTPRF", "PURA", "PWP2", "QKI", "RAB10", "RAB18", "RAB21", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAD50", "RAI14", "RALA", "RAPGEF2", "RASAL2", "RBM10", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM3", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCN1", "RCN2", "RDX", "REPS1", "RFC2", "RFT1", "RHOA", "RINT1", "RMND1", "RNF114", "RNF20", "RNF40", "RPA2", "RPL31", "RPL35", "RPRD2", "RSU1", "RTN2", "S100A13", "SC5D", "SCAMP4", "SCARB1", "SDAD1", "SEC16A", "SEC24A", "SEPT6", "SEPT7", "SET", "SF1", "SF3A1", "SF3A3", "SF3B2", "SFPQ", "SHOC2", "SIGMAR1", "SKIV2L", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC30A5", "SLC38A2", "SLC39A14", "SLC4A1AP", "SLIRP", "SMARCC2", "SMC3", "SMYD3", "SNX2", "SNX27", "SNX3", "SOAT1", "SORBS3", "SPAG9", "SPART", "SPECC1L", "SPEN", "SPTBN1", "SPTBN2", "SQLE", "SRPRA", "SRSF1", "SRSF3", "SRSF4", "SRSF9", "SSNA1", "STAG1", "STAM", "STAMBP", "STAT1", "STK4", "STOML2", "STRBP", "STT3B", "STX10", "STX7", "STXBP4", "SUB1", "SUGP1", "SUN1", "SUN2", "SUPT5H", "SYMPK", "SYVN1", "TAF15", "TBC1D15", "TBC1D9B", "TCEA1", "TEDC1", "THRAP3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM8B", "TIMM9", "TIMMDC1", "TMEM126B", "TMEM165", "TMEM199", "TMX3", "TNPO3", "TOX4", "TPD52", "TPM1", "TPR", "TRA2B", "TRIM21", "TRIR", "TRMT61A", "TSC22D3", "TSN", "TSPAN6", "TST", "TTC37", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TXNDC12", "TXNL1", "UBA5", "UBAP2L", "UBE3C", "UGDH", "UGGT1", "UNC119", "USO1", "USP15", "USP19", "USP48", "UTP15", "UTP6", "VIM", "VPS11", "VPS13D", "VPS26A", "VPS51", "VRK2", "VTA1", "WAPL", "WASHC5", "WBP11", "WDR45B", "WDR70", "WIZ", "WRNIP1", "XPO4", "YBX1", "YLPM1", "ZADH2", "ZC3H14", "ZC3H15", "ZC3H18", "ZCCHC3", "ZCRB1", "ZNF281", "ZNF318", "ZNF326", "ZPR1"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/idx2term.json b/protein_atlas_subcellular_location_all/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..010cf3327b99156196079bf3a2774e2a9918203b --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Microtubules", "1": "Actin filaments", "2": "Mitotic spindle", "3": "Nuclear membrane", "4": "Nuclear bodies"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/plot_0.png 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--- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..80c70ccea33e590db9aee08312c0074664586df2 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2944, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 137.66666666666666 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3e43e281a373b8bca41a5c651fccb0c2f656ad77 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C352/C352_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..df36fef1e194cf1fdb1e674ecbe969fabd541e06 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Microtubules 0.3416329816983676 0.965377192359135 0.3343559209152991 0.9999985311128926 1.0 46 P54105,Q96EV8,P13984,P55209,Q9NZZ3,Q13685,P04350,Q03001,Q13509,Q68CZ6,Q9BUF5,Q13813,P30040,O43768,O75330,P13807,Q9NV70 17 +Lipid droplets 0.4833339297503876 0.6946142129759625 0.4872971026996144 0.9999999997335778 1.0 10 Q01105,Q969E2,O60664 3 +Actin filaments 0.2908130840582087 0.4436454461693757 0.6572989430954381 0.9999999999999996 1.0 47 P09493,Q9P0K7,Q16181,Q6UW02,Q69YQ0,P49006,Q6P4Q7,Q96IZ0,Q9HCD5,P17812 10 +Lysosomes 0.4006425729544666 0.3275494260415857 0.7432523661725936 1.0 1.0 15 O15400 1 +Mitotic spindle 0.3838638202647286 0.2670336888479258 0.7894432226381047 1.0 1.0 19 Q15477,P04350,Q13509,Q02241,Q68CZ6,Q9BUF5 6 +Nuclear membrane 0.2812992082028695 0.22995393658608 0.8181275638116774 1.0 1.0 58 Q8NC56,A2RRP1,Q96G23,Q9UH99,Q8NFH5,Q9BW91,Q9Y2U8,Q9UKD2,Q9H1E5,P12270,O15260,Q96SK2,O94901,O75179,Q03252,P50402 16 +Intermediate filaments 0.3409026759388777 0.1920735780686253 0.8476845711995384 1.0 1.0 30 Q16352,Q15102,Q9BWS9 3 +Nuclear bodies 0.3210863574986353 0.0524240615697616 0.9581908021147404 1.0 1.0 110 Q15477,O60524,O75153,Q9UIV1,Q96DY7,P41214,P15927,Q7Z417,Q96BP3,Q9UQ84,O75874,Q9Y4E8,O14641,Q15056,Q8WVM7 15 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..83301ed63349e13921d8425120e74babefc8b81c --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATF7IP", "ATG3", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf73", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C20orf27", "C2CD2", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZB", "CARM1", "CARS", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC167", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKN2AIP", "CDV3", "CEBPZ", "CENPI", "CENPV", "CEP55", "CERS1", "CERS2", "CERS4", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHID1", "CHM", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "COQ9", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DPF2", "DPH5", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTNBP1", "DTX3L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EZR", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM210A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIPC1", "GLB1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAA1", "GPATCH11", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HEXA", "HGH1", "HGS", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1R", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPCAL4", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS10", "INTS11", "INTS12", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "ISCU", "ISOC1", "IST1", "ISYNA1", "ITGB1", "ITPA", "ITPK1", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF11", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LPP", "LRBA", "LRPPRC", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LSM12", "LSM2", "LSM4", "LSM6", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LYAR", "LYPLA1", "LYPLA2", "LZTFL1", "MACF1", "MAD2L1", "MAGED2", "MAN1A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED21", "METAP2", "METTL13", "MFN2", "MFSD3", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS14", "MRPS15", "MRPS16", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NELFCD", "NELFE", "NEMF", "NES", "NF1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXNAD1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGU", "PIH1D1", "PIK3R4", "PIN1", "PIN4", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLPBP", "PLRG1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLR1A", "POLR1C", "POLR1E", "POLR2B", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4C", "PPP5C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTK2", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM2", "PUM3", "PURB", "PUS1", "PWP1", "PWP2", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QRICH1", "QSOX2", "QTRT2", "RAB13", "RAB14", "RAB1A", "RAB23", "RAB24", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RASAL2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RDH13", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF114", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A8", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYVN1", "TAB1", "TACC3", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDP2", "TDRKH", "TECR", "TEDC1", "TELO2", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM106B", "TMEM109", "TMEM126A", "TMEM126B", "TMEM161A", "TMEM165", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM70", "TMEM87A", "TMEM97", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT10C", "TRMT1L", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TST", "TTC1", "TTC19", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXNDC5", "TXNDC9", "TXNL1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN7", "UCHL5", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VKORC1L1", "VMP1", "VPS11", "VPS13D", "VPS25", "VPS26A", "VPS29", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR77", "WDR82", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMYM4", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF638", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "ANKRD17", "CERS2", "CHID1", "CHMP5", "CLNS1A", "CLUH", "CNNM4", "CNOT7", "CTPS1", "CYP20A1", "DST", "DTNBP1", "DVL2", "EIF2D", "EIF4H", "EMD", "ENSA", "ERP29", "EXO1", "EXOC1", "GTF2F2", "GYS1", "HAUS3", "HMMR", "IDH1", "INA", "KIF23", "LEMD2", "LEMD3", "LMNB2", "MARCKSL1", "MRTO4", "MTBP", "NAP1L1", "NBAS", "NCOA5", "NEMF", "NUDT9", "NUFIP2", "NUP35", "PAFAH1B3", "PAWR", "PLIN3", "PPWD1", "RAI14", "RPA2", "SCAMP4", "SEPT7", "SET", "SKIV2L", "SPECC1L", "SPTAN1", "STAG1", "STX7", "SUN1", "SUN2", "SURF4", "TMEM209", "TMX4", "TPM1", "TPR", "TUBB3", "TUBB4A", "TUBB6", "USP15"]} \ No newline at end of file