diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..884813dd16650df34831385d765007d0befa28c2 --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Serine/threonine-protein kinase, active site [IPR008271]"} \ No newline at end of file diff --git a/interpro_active_site/basic/plot_0.png b/interpro_active_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ee79ba41c3dfd5253fd49690c8816c8b8d3bdf19 --- /dev/null +++ b/interpro_active_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:36bb2852c3a2162dca3619f93626618b5a55e6dacc400941982974ab2b3f8ce9 +size 150952 diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8d290706b2329e4970ec7d0a290ce6c1d75c52c0 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a29bd669647788d6772d7d78aef705a14bbe27995fdf7121659d37ad51f57b2c +size 84562 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cb12d35265d5747041586da7e5d2e3d9390f3622 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 57, + "title": "Average number of proteins per term", + "value": 2.9298245614035086 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3f6796694a1384965d96f5e3648a01d6792c2830 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fe0717527562e64a9b5f155d4a7609c5bdeece13 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Serine carboxypeptidase, serine active site [IPR018202] 0.9227439894623686 1.6161925143699285 0.1060526967300399 0.9983220486676844 0.2084484039176646 3 Q9H3G5 1 +Histidine acid phosphatase active site [IPR033379] 0.8425899280575528 1.4010345952636425 0.1612037281338352 0.9999554938510812 0.2429916023209237 2 Q9NPH0 1 +Serine/threonine-protein kinase, active site [IPR008271] 0.3199023138257428 1.0128699070754494 0.3111223039822341 0.9999999994055696 0.3855211158040728 56 P51812,Q15418,P49761,P31749,P05771 5 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..442c2a4f499c106a2a169712b51200d82af984be --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP3", "CASP7", "CDC34", "CDC7", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MARK3", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCB", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "RIPK1", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TAOK2", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1", "YES1"], "leading_proteins": ["ACP6", "AKT1", "CLK3", "CPVL", "PRKCB", "RPS6KA1", "RPS6KA3"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/advanced/plot_0.png b/interpro_binding_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ad8ea7a1c5ecb06242ccc2f6107a435848a2d3bf --- /dev/null +++ b/interpro_binding_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0aa8ecfeaa15d7ee7986de03d6ae324b6e2156fd40abc7f4ef82a706e481b64 +size 191017 diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..73c30eb04cc7ed44e0e71d59c90648406a898b8d --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Protein kinase, ATP binding site [IPR017441]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1ec56be3a6b4453721f1a26743b61e6c578bb73a --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e0a87fbedd96d150c3482c2cbe5335063ae47f08a1b86a2370283fb49ae87845 +size 141526 diff --git a/interpro_binding_site/basic/plot_1.png b/interpro_binding_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7ab2da35ca3a6aa1fa24630d57a53ebb352d1236 --- /dev/null +++ b/interpro_binding_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:31b61c7c6f7113e19c583ea5df427fc9a7d22156996ee6d326bdcf5ada3a0b1d +size 148830 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..fadd96e10d2b76c7987f9eca14440b2c22ae6e1c --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:08d0efb91a0bf77cf7553f1878f9b03e9bd70fbb1f20b39e6f093ec9ce590fcf +size 80365 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..57bb4ebeddb4674ea203ce9e576abaec409d22c2 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EF-Hand 1, calcium-binding site [IPR018247] 9 40 3.0981842212811737 0.0019471035133762 10.019417475728156 36.70631067961165 0.9532938980945532 0.3894555773109194 3.76037227687173 3.057484685571999 1.1082350706804749 0.3408841825650379 0.0007847566614169 0.0060275441501108 0.0402942577421927 1.926020230279072e-05 0.0001030255174711 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..51dd0bf8b7cc046196561188d48899df7d6ce013 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 30, + "title": "Average number of proteins per term", + "value": 5.366666666666666 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..47ebee2a9ca4e6d286429f3e679843fd874d9e1c --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..13a695334f8a1b656b8f16b250bdf77bf9450620 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.5549411608106891 3.0981842212811737 0.0019471035133762 0.0567935086399151 0.0235156588494556 40 Q96AY3,O43852,Q14257,Q02818,Q9BRK5,O95302,Q9Y680,Q9UBV8,Q9NWM8 9 +Peptidase M16, zinc-binding site [IPR001431] 0.7645143777320599 1.7713683562423082 0.0764994671176308 0.9081425233102022 0.1639274295377804 5 P22695,Q10713 2 +Protein kinase, ATP binding site [IPR017441] 0.3494024670687863 1.377765956052828 0.1682755601444781 0.996024571959448 0.2722689620752385 56 P51812,Q15418,P49761,P31749,P05771 5 +Beta tubulin, autoregulation binding site [IPR013838] 0.6570109046895831 1.287713168972308 0.1978458277201431 0.9986580528796504 0.2826368967430616 5 P07437,P68371 2 +PPM-type phosphatase, divalent cation binding [IPR000222] 0.3448474381116747 0.0051746020462481 0.9958712833444424 1.0 0.9958712833444424 3 P49593,O15355 2 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d51a6e43eef1607ece564880765542e6b90a011b --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "APEX2", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDC7", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQCB1", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARK2", "MARK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKACA", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TAOK2", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["AKT1", "CALU", "CLK3", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "NUCB1", "PEF1", "PMPCA", "PPM1F", "PPM1G", "PRKCB", "RCN2", "RPS6KA1", "RPS6KA3", "SDF4", "TUBB", "TUBB4B", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..57f6f9dafce477d2ab9290983cf12712a7411c24 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Intermediate filament protein, conserved site [IPR018039]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0c604742c359b07137e91d95489c99ec66836937 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:040a376eac5bd91ea729c8857d14d2a3c8d8ecda7d0f0c628ff3236f9aafd610 +size 182998 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..2f788a850fb62b80f5e786177233d211432b51c6 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Intermediate filament protein, conserved site [IPR018039]", "1": "Zinc finger, PHD-type, conserved site [IPR019786]", "2": "Zinc finger, RING-type, conserved site [IPR017907]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d4a8857b5cee0573b73c05cc9a5a4c49015344e9 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:36f8a0bbcccc7a648b206ab624b9f7034acc20b9d51543b422d0b4a7693f7114 +size 142588 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..67ad3c44001d538ddf610b7ec66643a453d80837 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d5783b20bb07bd36d5eab6f7ecfd999ad168270ea571ef5f5786a5d2d86abd3 +size 148634 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ef9a31f608ec159fefeed7156dfe6de7ac1e54ab --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72a966f65a5a7bc51fa801462dcef71ac0fdd3d8b7198bc3fc3cbf23f5277751 +size 150551 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..6d162637a36bd6800269436e428620c1c41deb76 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:882a85b26921088a23d9cc1ed741ecf21e6111627667f887410e360f6ff1f96b +size 117308 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8ee9947d2ea3cce56a757aef182c538a7d47632e --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Aldehyde dehydrogenase, cysteine active site [IPR016160] 2 8 2.509080372066254 0.0121045939449075 2.478155339805826 7.286407766990291 -0.1163447967243902 0.4155558234730984 1.8026432844079276 0.5916159446457568 1.150914295148441 0.2845969995849257 0.0010300959297083 0.0011617774889038 0.0001343549216781 0.0020064706347618 0.0141665154869097 +Intermediate filament protein, conserved site [IPR018039] 6 7 2.5087502859313235 0.0121159101326331 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.004613560888322 1.0 0.1596960736798767 0.0087554356838108 0.0001461959825676 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8095c6b6636548d944996d47a0f566e575afb13b --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 278, + "title": "Average number of proteins per term", + "value": 2.8309352517985613 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b1fa4ff8ed9a147bafaae6a53807998a27d65a2c --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ca3b29068b6c99f9f5c8b8db57e2c69fb7f7acad --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,28 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.795110761361625 2.509080372066254 0.0121045939449075 0.9661429971143471 0.043182346370154 8 P30837,O94788 2 +Intermediate filament protein, conserved site [IPR018039] 0.8435158501440898 2.5087502859313235 0.0121159101326331 0.9662506420635482 0.043182346370154 7 P08670,Q16352,P48681,Q03252,P07197,P20700 6 +Oxysterol-binding protein, conserved site [IPR018494] 0.756567136302336 1.9494078831183297 0.0512467338612703 0.9999995547407512 0.1344018114474825 6 Q9BZF3 1 +Haem oxygenase conserved site [IPR018207] 0.9381294964028772 1.7989635823104515 0.0720244416222084 0.9999999990555968 0.1654776427353218 2 P30519 1 +Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.6444335433544351 1.7557885938561508 0.0791245126964974 0.9999999998883512 0.1773920526582765 8 O94788 1 +Zinc finger, PHD-type, conserved site [IPR019786] 0.4575224086410248 1.328602583772571 0.1839791191786559 1.0 0.3321181502056257 19 O96028,P29375,Q9UPP1,Q92576,Q9UPN9,O94880,O15164,Q96L73,Q9ULU4 9 +Tubulin, conserved site [IPR017975] 0.6570109046895831 1.287713168972308 0.1978458277201431 1.0 0.3503257331605082 5 P07437,P68371 2 +Acyl-CoA-binding protein, ACBP, conserved site [IPR022408] 0.8327947295313286 1.2682268409356712 0.2047169543938292 1.0 0.3579327881854372 3 O75521 1 +Zinc finger, RING-type, conserved site [IPR017907] 0.4229231793546174 1.078001120122028 0.2810332562584263 1.0 0.4542281699990844 19 Q5VTR2,O75150,Q9UPN9,P38398,Q96EP0,P22681,Q9NS91,Q99590,Q9P1Y6 9 +Mini-chromosome maintenance, conserved site [IPR018525] 0.5697554048300135 1.0639550520182892 0.2873490619509344 1.0 0.4593310801759305 6 Q14566 1 +Polyprenyl synthetase, conserved site [IPR033749] 0.7328769020835315 0.8863836845152355 0.3754108080163267 1.0 0.5492852875186255 3 O95749 1 +DnaJ domain, conserved site [IPR018253] 0.3991215360395534 0.7354018157870007 0.4620948163320748 1.0 0.6236036841762952 12 Q96EY1,Q8WXX5,Q9Y2G8,Q96KC8 4 +ABC transporter-like, conserved site [IPR017871] 0.3778555016761653 0.6089864999422999 0.5425333872216718 1.0 0.6841991677600059 12 P08183 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.4260511266414398 0.6049443446645706 0.5452159772055514 1.0 0.6841991677600059 8 P20618,P28072,P49721,P28070 4 +Homeobox, conserved site [IPR017970] 0.6397122302158245 0.5899668043053368 0.5552129049949015 1.0 0.6859963892825894 2 P40425 1 +Guanylate kinase, conserved site [IPR020590] 0.4710933304541463 0.4737898885891913 0.6356497457711732 1.0 0.7424816358167485 5 Q9NZW5,Q00013 2 +Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.5835971223021547 0.4019461938206249 0.6877236253505763 1.0 0.7803557871324907 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.5835971223021547 0.4019461938206249 0.6877236253505763 1.0 0.7803557871324907 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.5835971223021547 0.4019461938206249 0.6877236253505763 1.0 0.7803557871324907 2 Q07820 1 +Chromo domain, conserved site [IPR023779] 0.4201309009464417 0.3852186471125546 0.7000754290105182 1.0 0.7911421514834311 6 Q14781,Q13185,P45973 3 +Bromodomain, conserved site [IPR018359] 0.3035621662060758 0.2183516077782634 0.8271551671835993 1.0 0.8982388143634398 12 O15164,Q92830,O60885,Q86U86 4 +Cyclic nucleotide-binding, conserved site [IPR018488] 0.4920863309352475 0.1701901780644668 0.8648605758062811 1.0 0.9190662955498552 2 P10644 1 +Methylthiotransferase, conserved site [IPR020612] 0.4785611510791323 0.1454808684486651 0.8843312198130833 1.0 0.9312275723789286 2 Q5VV42 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.3381625935030565 0.1093078417572279 0.9129583270440738 1.0 0.9505708423904587 6 Q9P2W9,O60499 2 +Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.4135251798561108 0.0614614999904531 0.950991674969663 1.0 0.9791692060798752 2 Q14155 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.3865860679332 0.0258038747801776 0.9794137712516195 1.0 0.997351752410074 3 O00429,Q9UQ16 2 +Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.3087769784172607 0.016345731188895 0.9869585741929884 1.0 1.0 2 O60573 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fe472fea4b9571349e57a7bf936f623e2b8bd38d --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site [IPR018168]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP4M1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CIAO1", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "COQ6", "CORO1B", "CORO1C", "CPOX", "CREBBP", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FTH1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HOXD13", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPA1", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KAT2A", "KATNA1", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSF", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PBX2", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAD18", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK2", "RNF114", "RNF14", "RNF2", "RNF20", "RNF31", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STARD9", "STMN1", "STRN", "STRN4", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP38", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ALDH1A2", "ALDH1B1", "ARHGEF7", "BRCA1", "BRD4", "CBL", "CBX2", "CBX3", "CBX5", "CDKAL1", "DNAJA3", "DNAJC1", "DNAJC16", "DNAJC9", "DNM1L", "DNM3", "ECI2", "EIF4E2", "GGPS1", "HMOX2", "INA", "KAT2A", "KDM5A", "LMNB1", "LMNB2", "MCL1", "MCM6", "MPP1", "MPP6", "NEFM", "NES", "NSD1", "NSD2", "OSBPL6", "PBRM1", "PBX2", "PHF14", "PHF3", "PHF8", "PHRF1", "PRKAR1A", 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[IPR000504]", "1": "EF-hand domain [IPR002048]", "2": "RNA recognition motif domain, eukaryote [IPR003954]", "3": "Intermediate filament, rod domain [IPR039008]", "4": "Zinc finger, RanBP2-type [IPR001876]", "5": "G-patch domain [IPR000467]", "6": "PWWP domain [IPR000313]", "7": "SET domain [IPR001214]", "8": "K Homology domain, type 1 [IPR004088]", "9": "K Homology domain [IPR004087]", "10": "WW domain [IPR001202]", "11": "Zinc finger, PHD-finger [IPR019787]", "12": "Zinc finger, PHD-type [IPR001965]", "13": "DnaJ domain [IPR001623]", "14": "Bromodomain [IPR001487]", "15": "GOLD domain [IPR009038]", "16": "Zinc finger, RING-type [IPR001841]", "17": "C2 domain [IPR000008]", "18": "Ubiquitin-associated domain [IPR015940]", "19": "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "20": "SAP domain [IPR003034]", "21": "Protein kinase domain [IPR000719]", "22": "Dbl homology (DH) domain [IPR000219]", "23": "PDZ domain [IPR001478]", "24": "Zinc finger C2H2-type [IPR013087]", "25": 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sha256:d1949b6dd92ac26bf92020b09cba4f37fd456ab9ccd0028cec8474378844844b +size 418811 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7158354e90dd4283bbd0f23a04c950e215e5ec45 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,20 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +RNA recognition motif domain [IPR000504] 52 120 5.372726882491356 7.75547528676608e-08 39.713592233009706 116.0 0.2316956716939257 0.5316884276370477 13.873754985119357 5.729331786381952 1.713447249572458 0.3950212299678106 6.243149399225533e-06 0.1973594205035791 0.0002610669975291 6.942966862407242e-09 2.48885077184093e-15 +EF-hand domain [IPR002048] 14 47 3.4562776639431982 0.0005476908281889 12.385922330097088 43.512135922330096 1.0171858714399242 0.3947118087831401 4.608360476919044 4.087317384177653 1.201458704248258 0.3652478399429377 0.0030919383331723 0.0115064399742295 0.0714976342213511 0.0001483335777357 9.272076262338654e-05 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 4 12 3.1620692799672523 0.0015665229007892 3.1262135922330097 10.111650485436892 0.9686720267359892 0.3700536707457866 1.7316562118191232 1.203619216216406 0.9607394322697528 0.3108814801432357 8.265557082495089e-05 0.0016377422378922 0.0066572828402184 0.0002022933287296 0.0002504856541451 +Protein kinase, C-terminal [IPR017892] 4 8 2.973544989374537 0.0029438124782277 2.0194174757281553 5.813106796116505 -0.2988592628930643 0.4464463186043645 1.2958528512612006 1.4996838042955702 1.115578313938598 0.314572943307665 0.0001427136226383 1.0 0.0274603336438859 0.0004179970223822 0.0089325963600969 +RNA recognition motif domain, eukaryote [IPR003954] 7 12 2.919027577003375 0.0035112516002 4.084951456310679 13.157766990291265 0.4053633607283609 0.5044278905686779 2.611599730621696 1.3534791070715837 0.9876170990304802 0.3281969373801077 0.0607884384663988 0.0944323477659319 0.0170518298819148 0.001453665706999 0.0003770934365041 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 4 7 2.768401943420722 0.0056331934117459 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.001354096353283 0.0550816697898294 0.0056684159955205 0.000142755965642 0.000160552482799 +AGC-kinase, C-terminal [IPR000961] 4 11 2.710390560863374 0.006720402222418 2.983009708737864 9.12378640776699 -0.2973365060025665 0.4860151458305204 1.8726966875073192 2.3855790921417372 1.0207222480726916 0.3173037742419929 0.0019871329871855 1.0 0.0748026769138462 0.0053616069246772 0.0772454186514108 +Intermediate filament, rod domain [IPR039008] 6 7 2.5087502859313235 0.0121159101326331 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.0082299219600807 1.0 0.191600110602388 0.0153906222854723 0.0004973671187583 +Zinc finger, RanBP2-type [IPR001876] 7 10 2.306652433874394 0.0210742039532541 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 0.0607884384663988 1.0 0.0170518298819148 0.0135296171343662 0.002864460747413 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 3 5 2.248282194745712 0.0245582013424412 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 8.72823867368061e-06 0.0370595951599339 0.002465796513642 2.1797401302891516e-05 0.0003337445501144 +Aminopeptidase N-like , N-terminal domain [IPR045357] 3 5 2.248282194745712 0.0245582013424412 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 8.72823867368061e-06 0.0370595951599339 0.002465796513642 2.1797401302891516e-05 0.0003337445501144 +Alpha/beta hydrolase fold-1 [IPR000073] 2 7 2.2465585333957856 0.0246682547753507 2.1480582524271843 6.504854368932039 -1.1232357203836367 0.1889577993756418 1.0168106985111116 1.3768106271609897 1.2614879173700857 0.2036079596667034 0.003256901879322 0.0024970154667983 0.000440337804097 0.0062267265321947 0.0401461367370898 +Aldehyde dehydrogenase domain [IPR015590] 2 10 2.216200014154553 0.0266778069192621 3.2985436893203883 9.529126213592232 -0.5613485854973601 0.3657232034282902 1.9683657938952 0.6908740865654212 1.1218179525542225 0.2726859723953302 0.0021777683667008 0.0019049706229129 0.0002902447274798 0.0041946485896371 0.0280386150660574 +G-patch domain [IPR000467] 8 15 2.0544331370206392 0.0399337886046229 5.650485436893204 13.444174757281552 -0.405487239385642 0.5555291788030755 2.990953148283137 1.7637917145111943 0.8276088274784031 0.3061571987973734 1.0 1.0 1.0 0.0983610682747182 0.0004973671187583 +Pleckstrin homology domain [IPR001849] 3 30 2.0333902733080955 0.0420131092531304 7.577669902912621 25.652912621359224 -0.0316373490872633 0.6250683324241235 5.069544167456597 6.588340411720883 0.8478431018941189 0.3044798814492656 0.5429002340542437 0.6163162766509123 0.8592353865109894 0.7222606509700791 0.989958407867872 +PWWP domain [IPR000313] 6 9 2.0019344252650275 0.0452917845947644 3.3058252427184467 8.240291262135923 -0.3576134211980867 0.4993280051564587 1.9666306133740248 1.4508209636493494 0.9362848674719632 0.2971220842011314 0.0459708160418879 1.0 0.1596960736798767 0.0087554356838108 0.0544656750173612 +Peptidase M16, C-terminal [IPR007863] 3 7 1.9873333085967173 0.0468854728445067 2.6067961165048543 7.0 0.7914914082442276 0.4366893661235884 1.5075062759483802 0.0 0.8715475629418188 0.3304871916560691 1.0 1.0 1.0 1.0 0.0034775277607499 +Peptidase M16, N-terminal [IPR011765] 3 7 1.9873333085967173 0.0468854728445067 2.6067961165048543 7.0 0.7914914082442276 0.4366893661235884 1.5075062759483802 0.0 0.8715475629418188 0.3304871916560691 1.0 1.0 1.0 1.0 0.0034775277607499 +Major facilitator superfamily domain [IPR020846] 3 5 1.9684565956747733 0.0490155255054087 1.8883495145631068 4.121359223300971 0.8776223597987594 0.2728824130413255 1.233496960525634 1.4580976091979958 1.2936014196902064 0.266909732326598 0.1127228947746968 1.0 0.2518545844225215 0.0352396407582777 0.0560616912320164 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e1168ab4d11632d604cf48566f79e18e98162cec --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 2760, + "title": "Average number of proteins per term", + "value": 2.2333333333333334 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c4a17351faf05db42dcbe28d34b4a07910fe9849 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..17c44593f3697f56fc55e482eb4b8f4cbf7a99a4 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,254 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +RNA recognition motif domain [IPR000504] 0.5709055733354446 5.372726882491356 7.75547528676608e-08 0.00021402821891 0.0002140511179175 120 O60506,Q96DH6,Q07955,Q9UHX1,P18615,O43390,P33240,P19338,Q9P2K5,Q13148,P98175,O14979,Q86V81,P22626,Q13595,Q8IXT5,P98179,Q14011,Q99729,Q13151,P62995,P38159,Q96PK6,P31942,Q96I25,Q15056,P23246,P23588,Q01844,P35637,Q96E39,P52272,O75494,P78332,Q01130,Q92804,Q01085,P43243,Q15233,P52597,O15047,P52756,Q8WXF0,Q13242,P55795,Q8N684,Q96EP5,Q76FK4,P51991,Q15427,P31943,Q8WXF1 52 +EF-hand domain [IPR002048] 0.557825055088661 3.4562776639431982 0.0005476908281889 0.7795403929911031 0.0752019592236019 47 Q96AY3,Q9UJS0,Q14257,O43852,Q02818,Q9BRK5,O95302,Q96D71,P0DP25,Q9Y680,Q9UBV8,Q9NWM8,P41208,Q8IYU8 14 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.8146744908351062 3.1620692799672523 0.0015665229007892 0.9867928015215388 0.0752019592236019 12 O95302,Q96AY3,Q9NWM8,Q9Y680 4 +Protein kinase, C-terminal [IPR017892] 0.8946966041805415 2.973544989374537 0.0029438124782277 0.9997074588115992 0.0752019592236019 8 Q15418,P31749,P51812,P05771 4 +RNA recognition motif domain, eukaryote [IPR003954] 0.7684441694312378 2.919027577003375 0.0035112516002 0.99993921139556 0.0752019592236019 12 Q14011,Q9UHX1,Q96E39,P38159,Q01130,Q01085,Q96I25 7 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.9020241513254688 2.768401943420722 0.0056331934117459 0.999999830696069 0.0755922931429085 7 O43169,Q8WUJ1,Q9UMX5,O15173 4 +AGC-kinase, C-terminal [IPR000961] 0.7642694738473319 2.710390560863374 0.006720402222418 0.9999999917323608 0.0769209913732234 11 Q15418,P31749,P51812,P05771 4 +Intermediate filament, rod domain [IPR039008] 0.8435158501440898 2.5087502859313235 0.0121159101326331 0.9999999999999976 0.0907552623874927 7 P08670,Q16352,P48681,Q03252,P07197,P20700 6 +Zinc finger, RanBP2-type [IPR001876] 0.7184721123073857 2.306652433874394 0.0210742039532541 1.0 0.1075134989112408 10 P52756,Q01844,P49790,P35637,Q96EP0,Q92804,P98175 7 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8745600833761595 2.2482821947457117 0.0245582013424412 1.0 0.1139648987866733 5 P55786,Q9UIQ6,P09960 3 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8745600833761595 2.2482821947457117 0.0245582013424412 1.0 0.1139648987866733 5 P55786,Q9UIQ6,P09960 3 +Alpha/beta hydrolase fold-1 [IPR000073] 0.7862213137320173 2.2465585333957856 0.0246682547753507 1.0 0.1142355422482684 7 P07099,P34913 2 +Aldehyde dehydrogenase domain [IPR015590] 0.7011467058862818 2.216200014154553 0.0266778069192621 1.0 0.1189227876760215 10 P30837,O94788 2 +G-patch domain [IPR000467] 0.5949175452177877 2.0544331370206392 0.0399337886046229 1.0 0.1493762445695116 15 Q5T3I0,P52756,Q8IWX8,P78332,Q9UBB9,Q8IWZ8,P98175,Q96BK5 8 +Pleckstrin homology domain [IPR001849] 0.4813944729720474 2.0333902733080955 0.0420131092531304 1.0 0.1523464533767565 30 P31749,Q9H4L5,Q9BZF3 3 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.9902158273381296 2.013139433074656 0.0440999628166456 1.0 0.1574591169132496 2 P98179 1 +PWWP domain [IPR000313] 0.6767285886643463 2.0019344252650275 0.0452917845947644 1.0 0.1596130550028595 9 O75475,O96028,Q9Y3E1,Q7Z4V5,Q96L73,P51858 6 +Peptidase M16, C-terminal [IPR007863] 0.7311971155203967 1.9873333085967175 0.0468854728445067 1.0 0.1620210364804677 7 P22695,Q5JRX3,Q10713 3 +Peptidase M16, N-terminal [IPR011765] 0.7311971155203967 1.9873333085967175 0.0468854728445067 1.0 0.1620210364804677 7 P22695,Q5JRX3,Q10713 3 +Major facilitator superfamily domain [IPR020846] 0.8093827106506213 1.9684565956747733 0.0490155255054087 1.0 0.167261344911923 5 Q9Y5Y0,Q14728,P53985 3 +Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.9792805755395684 1.968407005521582 0.0490212264909422 1.0 0.167261344911923 2 P51812 1 +SET domain [IPR001214] 0.6519936452959157 1.954660478918726 0.0506231577505555 1.0 0.1703901407213822 10 O15047,O96028,Q9H7B4,Q03164,Q8WTS6 5 +Poly(ADP-ribose) polymerase, regulatory domain [IPR004102] 0.9720863309352517 1.938906688421372 0.0525127013904787 1.0 0.1739916636707337 2 Q9UGN5 1 +WGR domain [IPR008893] 0.9720863309352517 1.938906688421372 0.0525127013904787 1.0 0.1739916636707337 2 Q9UGN5 1 +K Homology domain, type 1 [IPR004088] 0.4857488133021617 1.873031284167343 0.0610640651151948 1.0 0.1894573148545126 25 P51114,P61978,Q96I24,Q96AE4,O75525,Q07666,Q92945 7 +Pleckstrin homology domain 8 [IPR041680] 0.9484892086330932 1.8417739657133865 0.0655082197097147 1.0 0.1962101715814505 2 Q9BZF3 1 +Protein Kinase B, pleckstrin homology domain [IPR039026] 0.9450359712230216 1.8275145046965624 0.0676224473714373 1.0 0.199902430567088 2 P31749 1 +Survival motor neuron [IPR010304] 0.944460431654676 1.8251368753247497 0.0679803767292814 1.0 0.2006693473506063 2 O75940 1 +K Homology domain [IPR004087] 0.4828981944844157 1.8198191671461903 0.0687865478347518 1.0 0.2017543804717481 24 P51116,P51114,Q9NRX1,Q92667,Q96PU8,P61978,Q96AE4,O75525,Q96I24,Q07666,Q92945 11 +Post-SET domain [IPR003616] 0.7741241439982289 1.8138659470438503 0.0696983665127239 1.0 0.2029192949104622 5 O15047,O96028,Q03164 3 +RBM1CTR [IPR012604] 0.941007194244604 1.8108648929506597 0.0701617681602257 1.0 0.2035340899454419 2 P38159 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.9378417266187048 1.7977730582301477 0.072212978450695 1.0 0.2061094317724078 2 O15460 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.9372661870503594 1.7953917977610572 0.0725912983751806 1.0 0.206548436613916 2 A6NIH7 1 +Far upstream element-binding protein, C-terminal [IPR015096] 0.9364028776978416 1.7918193786934773 0.0731619035903161 1.0 0.2077436768613915 2 Q96AE4 1 +Zinc finger, CHHC-type [IPR012996] 0.9668969487622334 1.785606323280539 0.0741630223589919 1.0 0.2096380801261494 3 P55795,P52597 2 +ERAP1-like C-terminal domain [IPR024571] 0.964306275187103 1.775708798595394 0.0757809264280167 1.0 0.2132062761889155 3 P55786,Q9UIQ6 2 +KHDRBS, Qua1 domain [IPR032571] 0.9283453237410068 1.758447009937674 0.0786714803429733 1.0 0.2180053069745044 2 O75525 1 +Sam68, tyrosine-rich domain [IPR032335] 0.9283453237410068 1.758447009937674 0.0786714803429733 1.0 0.2180053069745044 2 O75525 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.9225899280575536 1.7345780435416105 0.0828155712910834 1.0 0.2243091037913545 2 O60506 1 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.9526981940913845 1.7312906015481544 0.0833999468742452 1.0 0.2252288193472767 3 O43823 1 +BSD domain [IPR005607] 0.9105035971223016 1.6843746761566858 0.0921092817006308 1.0 0.2400581846022106 2 Q9NW68 1 +HDGF-related, PWWP domain [IPR035496] 0.7981572127843475 1.6761281630711338 0.0937130913849233 1.0 0.242634270377475 4 Q7Z4V5,Q9Y3E1,P51858 3 +GYF domain [IPR003169] 0.9018705035971216 1.6484564652994198 0.0992590372187334 1.0 0.2491936677958754 2 O95400 1 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.6175364666541295 1.6152612011419851 0.1062541419995766 1.0 0.2609087472587468 8 Q13464,P05771,Q9H0H5 3 +Poly(ADP-ribose) polymerase, catalytic domain [IPR012317] 0.9210093919053496 1.6095087096560008 0.107505152085578 1.0 0.2632779234748851 3 Q9UGN5 1 +OCRE domain [IPR041591] 0.9194012665515248 1.6033106102805277 0.1088660951269266 1.0 0.26623568741193 3 P78332,P52756 2 +FAD-binding domain, PCMH-type [IPR016166] 0.8791366906474811 1.5536853979894736 0.1202594778052463 1.0 0.2805715627578022 2 Q15392 1 +FAD linked oxidase, N-terminal [IPR006094] 0.8791366906474811 1.5536853979894736 0.1202594778052463 1.0 0.2805715627578022 2 Q15392 1 +Small acidic protein-like domain [IPR028124] 0.8699280575539559 1.515240723777646 0.1297114535029271 1.0 0.2934168623773824 2 O00193 1 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.8610071942446034 1.4779790822543055 0.1394133771978714 1.0 0.3039343768294826 2 Q15067 1 +Sirtuin family, catalytic core domain [IPR026590] 0.8831773934259888 1.463353823003924 0.1433705871646775 1.0 0.3098690842400235 3 Q8IXJ6 1 +SWAP/Surp [IPR000061] 0.650235157363308 1.4505070822712445 0.1469171656615611 1.0 0.3162959260732516 6 Q8IWZ8,Q8IWX8 2 +Zinc finger, TFIIB-type [IPR013137] 0.8480575539568336 1.4238763253042508 0.1544822762045647 1.0 0.3253577962261411 2 Q00403 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8684513529073062 1.4063293349797996 0.1596263531346258 1.0 0.3312986290227484 3 P07197,P08670 2 +GPAT/DHAPAT, acyltransferase domain [IPR041728] 0.8402877697841716 1.3914182319549702 0.1640986391265619 1.0 0.3342525785898974 2 O15228 1 +Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520] 0.8402877697841716 1.3914182319549702 0.1640986391265619 1.0 0.3342525785898974 2 O15228 1 +WW domain [IPR001202] 0.495748760300515 1.3867696059865218 0.165512027907738 1.0 0.3353988230729492 14 Q6ZWJ1,O75400,Q8WYQ5,Q96PU5,P46934 5 +Zinc finger, PHD-finger [IPR019787] 0.4275507986285055 1.371823477021592 0.1701183968869841 1.0 0.3405576498923848 24 O96028,P29375,Q9UPP1,Q92576,Q9UPN9,Q03164,O94880,O15164,Q96L73,Q9P1Y6,Q9ULU4 11 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.8511801957397771 1.3394199786478462 0.1804339890244901 1.0 0.3497560671798355 3 O15460,P13674 2 +LEM domain [IPR003887] 0.6242582809340999 1.3260757392423184 0.1848146112073643 1.0 0.3534915640556656 6 Q9Y2U8,P42166,Q86XL3 3 +Lamin tail domain [IPR001322] 0.8425446171560111 1.3059717475365358 0.1915621655108963 1.0 0.3616358254514869 3 Q03252,P20700 2 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.8161151079136677 1.2905448860699518 0.1968615376910747 1.0 0.369869192666689 2 P51114 1 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.6570109046895831 1.287713168972308 0.1978458277201431 1.0 0.371154192955124 5 P07437,P68371 2 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.6570109046895831 1.287713168972308 0.1978458277201431 1.0 0.371154192955124 5 P07437,P68371 2 +Acyl-CoA-binding protein, ACBP [IPR000582] 0.8327947295313286 1.2682268409356712 0.2047169543938292 1.0 0.3786989236775929 3 O75521 1 +NSD, Cys-His rich domain [IPR041306] 0.8094964028776964 1.2629758943818812 0.2065978429173252 1.0 0.3806823179230059 2 O96028 1 +AWS domain [IPR006560] 0.8094964028776964 1.2629758943818812 0.2065978429173252 1.0 0.3806823179230059 2 O96028 1 +NOPS [IPR012975] 0.8267127230857773 1.2446975638240585 0.2132429418165156 1.0 0.3881815918905237 3 Q8WXF1,P23246 2 +Protein of unknown function DUF3715 [IPR022188] 0.8040287769784158 1.2402256515900918 0.2148919430425357 1.0 0.3889191887196057 2 Q9UK61 1 +YTH domain [IPR007275] 0.6424696808698326 1.2216027071951336 0.2218579043880648 1.0 0.3986676401901483 5 Q9Y5A9,Q7Z739,Q96MU7 3 +Zinc finger, PHD-type [IPR001965] 0.4034783429302101 1.2191605183822112 0.2227832738713944 1.0 0.3992739194058756 26 O96028,P29375,Q9UPP1,Q92576,Q9UPN9,Q03164,O94880,Q7Z5J4,O15164,Q96L73,Q9P1Y6,Q9ULU4 12 +Lens epithelium-derived growth factor, integrase-binding domain [IPR021567] 0.7976978417266172 1.2139152816124863 0.2247800767670003 1.0 0.4012332285039101 2 Q7Z4V5 1 +RABX5, catalytic core helical domain [IPR041545] 0.7948201438848905 1.2019687745058525 0.2293756263319393 1.0 0.4059669384076235 2 Q14C86 1 +VPS9 domain [IPR003123] 0.7948201438848905 1.2019687745058525 0.2293756263319393 1.0 0.4059669384076235 2 Q14C86 1 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.7942446043165452 1.199580501254117 0.2303023030658324 1.0 0.4061561383141837 2 Q13505 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.7942446043165452 1.199580501254117 0.2303023030658324 1.0 0.4061561383141837 2 Q13505 1 +Heat shock chaperonin-binding [IPR006636] 0.6371803826216278 1.1975531368863117 0.231091029392531 1.0 0.4070269566837176 5 Q9BSL1,Q9NRR5 2 +Zinc finger, C3HC4 RING-type [IPR018957] 0.8126079447322944 1.1902006070055675 0.233967554679622 1.0 0.4102607693238607 3 Q5VTR2,O75150 2 +Mab-21 domain [IPR024810] 0.7907913669064733 1.1852584227439458 0.2359152869484582 1.0 0.411387481710915 2 Q8IWB1 1 +Tudor domain [IPR002999] 0.5252025154759704 1.18490988928964 0.2360530769284383 1.0 0.411387481710915 9 O75940 1 +DnaJ domain [IPR001623] 0.4305964432607115 1.1837546198124649 0.2365102107318391 1.0 0.4115089840816887 20 O14976,Q8WXX5,Q13217,Q96KC8,Q9Y2G8,O75190,O75937,Q96EY1,Q9UGP8 9 +SAC3/GANP/THP3, conserved domain [IPR005062] 0.7902158273381279 1.1828727108353447 0.2368595983274828 1.0 0.4115532312758063 2 O60318 1 +Glutathione S-transferase, N-terminal [IPR004045] 0.5943131931538953 1.1820676487198185 0.2371788597366446 1.0 0.4115532312758063 6 P21266 1 +Sterol-sensing domain [IPR000731] 0.7833093525179838 1.154275384710882 0.248387284918917 1.0 0.423972706388769 2 O15118 1 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.6239548556134967 1.137446393598816 0.255351722207942 1.0 0.4329058681166584 5 Q96G23,Q15629 2 +Bromodomain [IPR001487] 0.4342461684071666 1.1150597084501408 0.2648248359541956 1.0 0.4435173223504732 18 Q6PL18,O60885,Q86U86,Q9UPN9,Q9NPI1,Q03164,O15164,Q92830,Q9ULU4 9 +COMM domain [IPR017920] 0.7732374100719406 1.1126865276819025 0.2658430836390693 1.0 0.4444136346722176 2 Q86X83 1 +GOLD domain [IPR009038] 0.5221594980127221 1.107682625264629 0.2679989056285898 1.0 0.447475486711983 8 Q15363,Q9Y3B3,Q9BVK6,Q9H3P7,P49755 5 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.7880924369843243 1.0958337871362347 0.2731515195347074 1.0 0.4499489458286588 3 Q9BYT8 1 +Histidine kinase domain [IPR005467] 0.7689208633093507 1.0949103435532623 0.2735559170653947 1.0 0.4499489458286588 2 Q15118 1 +Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955] 0.7689208633093507 1.0949103435532623 0.2735559170653947 1.0 0.4499489458286588 2 Q15118 1 +BAG domain [IPR003103] 0.6596602361071255 1.087508582004808 0.2768121078978507 1.0 0.4543806871613983 4 Q9UL15,O95817,O95429 3 +ABC transporter type 1, transmembrane domain [IPR011527] 0.5141745998311094 1.0649829369091075 0.2868836513638517 1.0 0.4652873769112474 8 P08183 1 +MCM N-terminal domain [IPR027925] 0.5697554048300135 1.0639550520182892 0.2873490619509344 1.0 0.4652873769112474 6 Q14566 1 +PB1 domain [IPR000270] 0.7571223021582714 1.0464904218486932 0.2953346648269104 1.0 0.4727941187690405 2 Q13501 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.7748992515831848 1.0453188512054623 0.295875627865525 1.0 0.4728527694897794 3 P61289,Q9UL46 2 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.7748992515831848 1.0453188512054623 0.295875627865525 1.0 0.4728527694897794 3 P61289,Q9UL46 2 +CARG-binding factor, N-terminal [IPR012956] 0.7553956834532354 1.0394272389059038 0.2986060812908371 1.0 0.4758387900477543 2 Q99729 1 +Transcription factor IIS, N-terminal [IPR017923] 0.6467952661635825 1.0329408201826022 0.3016315943056944 1.0 0.4769394075312734 4 Q14241,Q96ST2 2 +BAT2, N-terminal [IPR009738] 0.7714450201496785 1.0321326078412163 0.3020100002094716 1.0 0.4769394075312734 3 Q9Y520,Q5JSZ5 2 +Ubiquitin-like domain, USP-type [IPR028135] 0.7528057553956815 1.0288442031133342 0.303552891411742 1.0 0.476961346107798 2 P51784 1 +Spen paralogue and orthologue SPOC, C-terminal [IPR012921] 0.6446140649324567 1.0237094282561008 0.3059725408085372 1.0 0.47846131027284 4 Q96T37,Q92576 2 +Potentiating neddylation domain [IPR005176] 0.7467625899280557 1.004208013833136 0.3152783602059683 1.0 0.4854422683009868 2 Q92564 1 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.530004716499519 0.9915745040619264 0.3214051316278377 1.0 0.4898176217584044 7 O15460,P13674 2 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.530004716499519 0.9915745040619264 0.3214051316278377 1.0 0.4898176217584044 7 O15460,P13674 2 +Fxr1, tudor domain [IPR041560] 0.7602187679907806 0.9894086018248756 0.3224632676576162 1.0 0.4898176217584044 3 P51114,P51116 2 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7602187679907806 0.9894086018248756 0.3224632676576162 1.0 0.4898176217584044 3 P51114,P51116 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7602187679907806 0.9894086018248756 0.3224632676576162 1.0 0.4898176217584044 3 P51114,P51116 2 +Agenet-like domain [IPR008395] 0.7602187679907806 0.9894086018248756 0.3224632676576162 1.0 0.4898176217584044 3 P51114,P51116 2 +Sorting nexin, N-terminal [IPR005329] 0.7381294964028756 0.9691648863693298 0.3324629275442325 1.0 0.4986943913163488 2 Q13596 1 +F-box domain [IPR001810] 0.5864614999417708 0.9677756752589916 0.3331564146304739 1.0 0.498921163526917 5 Q8NEZ5 1 +Ran binding domain [IPR000156] 0.623054984847691 0.932881481829343 0.3508811645899099 1.0 0.5170485927753078 4 Q9H6Z4 1 +High mobility group box domain [IPR009071] 0.4484869651568259 0.921476637496145 0.3568016331182757 1.0 0.5235648521068738 11 Q969G3,O96028 2 +EXPERA domain [IPR033118] 0.7254676258992785 0.9181318548830724 0.3585498395265221 1.0 0.5247070822339347 2 Q5BJF2 1 +RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130] 0.7194244604316524 0.8939459079231563 0.3713508334100484 1.0 0.537174161536548 2 Q96DH6 1 +RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126] 0.7194244604316524 0.8939459079231563 0.3713508334100484 1.0 0.537174161536548 2 Q96DH6 1 +MCM domain [IPR001208] 0.5075616128929783 0.8797267466479303 0.3790073563272482 1.0 0.5426247511407931 7 Q14566 1 +MCM OB domain [IPR033762] 0.5075616128929783 0.8797267466479303 0.3790073563272482 1.0 0.5426247511407931 7 Q14566 1 +MCM, AAA-lid domain [IPR041562] 0.5075616128929783 0.8797267466479303 0.3790073563272482 1.0 0.5426247511407931 7 Q14566 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.7251409337063828 0.8575583207308141 0.3911363980093338 1.0 0.5516282363340631 3 P35611 1 +Zinc finger, RING-type [IPR001841] 0.3340299909243418 0.8500675669961352 0.3952875221166605 1.0 0.555213008163859 35 Q5VTR2,O96028,O75150,Q9UPN9,Q5W0B1,P38398,Q96T51,Q9H270,Q96DX4,P22681,Q5XPI4,Q9NS91,O15164,Q99590,Q9P1Y6,Q6UWE0 16 +Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.6011420675522803 0.8415936275516426 0.4000154574490251 1.0 0.5592921289560837 4 P51784,Q9Y4E8 2 +C2 domain [IPR000008] 0.3890734738003098 0.8342347028455095 0.4041487392791325 1.0 0.5618759950540305 19 Q96PE3,Q86YQ8,O14795,Q6WKZ4,Q96PU5,P05771 6 +GRIP domain [IPR000237] 0.7033093525179831 0.8300684721309181 0.4065000713690532 1.0 0.5624668001619475 2 Q8IWJ2 1 +BTB/POZ domain [IPR000210] 0.5969684108033183 0.8243581520974118 0.409736085469415 1.0 0.5646187950492922 4 Q96DT7,Q96CX2 2 +Ubiquitin-associated domain [IPR015940] 0.3868687932435282 0.7829639571997203 0.433648277820398 1.0 0.5832696134426406 18 Q9NRR5,Q14157,Q9BSL1,Q96EP0,P22681,Q13501,Q7KZI7 7 +Matrin/U1-C-like, C2H2-type zinc finger [IPR003604] 0.4572346577187474 0.7639623929360398 0.4448896539352387 1.0 0.5926136316897967 8 Q9ULV3,Q5VUA4,Q96KR1,P43243,Q14966 5 +Methyl-CpG DNA binding [IPR001739] 0.5390254118559005 0.7570968889691202 0.4489918177720147 1.0 0.5952878621387625 5 O95983,Q9UIS9,P51608 3 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.5799492200574099 0.754693398125763 0.4504329686407702 1.0 0.596130944505684 4 Q13596 1 +Death domain [IPR000488] 0.696028659750773 0.7507258554851828 0.4528176592510191 1.0 0.5970868636657529 3 Q13546 1 +GINS subunit, domain A [IPR021151] 0.6846415194838142 0.7097770287229319 0.4778424161994214 1.0 0.6159948943065873 3 Q9BRT9 1 +SAP domain [IPR003034] 0.3883872012658081 0.6977642253678479 0.4853246552998094 1.0 0.6221532970866113 14 Q9BUJ2,Q1KMD3,P12956,Q9NS91,Q14151,Q15424,P82979 7 +LEM-like domain [IPR013146] 0.6566906474820116 0.6517937847676579 0.514534211662518 1.0 0.641432258106224 2 P42166 1 +Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750] 0.6543884892086305 0.6432990465733496 0.5200300748255071 1.0 0.6452321403969895 2 Q7Z5L9 1 +VHS domain [IPR002014] 0.6517985611510764 0.6337828409076842 0.5262225529450435 1.0 0.6507374887120079 2 O14964 1 +Matrin/U1-C, C2H2-type zinc finger [IPR000690] 0.476300962499352 0.625160909136326 0.5318654552120416 1.0 0.6532473487197791 6 P43243,Q12874 2 +3'-5' exonuclease domain [IPR002562] 0.6587442125376923 0.6188227376230692 0.5360331414753596 1.0 0.6551563393298387 3 Q14191 1 +Extended PHD (ePHD) domain [IPR034732] 0.5447865487298489 0.6147806561938661 0.5386995856725447 1.0 0.6561003881544998 4 Q03164,O94880 2 +NudC N-terminal domain [IPR025934] 0.6457553956834503 0.6117498245438381 0.540703291410016 1.0 0.6563174974366969 2 Q9Y266 1 +ABC transporter-like, ATP-binding domain [IPR003439] 0.3778555016761653 0.6089864999422999 0.5425333872216718 1.0 0.6579051620087056 12 P08183 1 +Transcription elongation factor S-II, central domain [IPR003618] 0.655440414507762 0.6074644891771162 0.5435427021307855 1.0 0.6582614558494813 3 P23193,Q92576 2 +Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346] 0.6423021582733783 0.5992709763763406 0.5489921989479927 1.0 0.660801774573249 2 Q8WXI9 1 +PSP, proline-rich [IPR006568] 0.6417266187050331 0.597199267022676 0.5503743485133497 1.0 0.6621145913659102 2 Q6NZY4 1 +DDE superfamily endonuclease domain [IPR004875] 0.6405755395683423 0.5930628872780274 0.5531390664975728 1.0 0.6634784109227732 2 Q7Z3K3 1 +HTH CenpB-type DNA-binding domain [IPR006600] 0.6405755395683423 0.5930628872780274 0.5531390664975728 1.0 0.6634784109227732 2 Q7Z3K3 1 +Guanylate kinase-like domain [IPR008144] 0.447106079026737 0.5876109188963485 0.556793480399949 1.0 0.6635594371797046 7 Q9NZW5,Q00013,Q9UDY2,O14936 4 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.447106079026737 0.5876109188963485 0.556793480399949 1.0 0.6635594371797046 7 Q9NZW5,Q00013,Q9UDY2,O14936 4 +Zinc finger, CCHC-type [IPR001878] 0.4211553588457293 0.5806134716355934 0.5615009907512409 1.0 0.6678984009563574 8 Q6NZY4,Q9BWF3,Q15637 3 +Zinc finger, CCCH-type [IPR000571] 0.3640281454284878 0.5631256545330026 0.573349323321934 1.0 0.6744175186972392 15 Q6PJT7,O15504,Q86VM9,Q9UGR2 4 +GRAM domain [IPR004182] 0.5312410020155554 0.5627396936378882 0.5736121508687773 1.0 0.6744175186972392 4 Q13614,Q0IIM8,Q969T9 3 +Chromo domain subgroup [IPR017984] 0.6404720782959018 0.556790229935324 0.5776707598923867 1.0 0.6764409407310086 3 Q13185,P45973 2 +Chromo shadow domain [IPR008251] 0.6404720782959018 0.556790229935324 0.5776707598923867 1.0 0.6764409407310086 3 Q13185,P45973 2 +EF-hand, Ca insensitive [IPR014837] 0.6318364997121366 0.5281842547815094 0.5973714565646051 1.0 0.6910080553723009 3 P12814,Q13813 2 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.6272308578007946 0.5131299363492481 0.6078604320066869 1.0 0.7019643482587682 3 P51784,Q9Y4E8 2 +Protein kinase domain [IPR000719] 0.262124657994592 0.4837073341324076 0.6285935874626076 1.0 0.7172047546080186 70 P51812,Q15418,P49761,P31749,P05771 5 +Phospholipid/glycerol acyltransferase [IPR002123] 0.4009531960652654 0.4826078102151132 0.6293742325020768 1.0 0.7177171589059981 8 O15228,Q6UWP7 2 +MHC class I-like antigen recognition-like [IPR011161] 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.7177171589059981 3 P10321 1 +Immunoglobulin C1-set [IPR003597] 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.7177171589059981 3 P10321 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.7177171589059981 3 P10321 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.7177171589059981 3 P10321 1 +BRCT domain [IPR001357] 0.3703479373615665 0.479710610001271 0.631433182438002 1.0 0.7180698737243039 11 P09874,P38398 2 +Fatty acid desaturase domain [IPR005804] 0.6060431654676226 0.4737689664811828 0.6356646669495853 1.0 0.7211075185915493 2 O15121 1 +U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.6131679282266012 0.4680930916075918 0.6397180193824272 1.0 0.7248036672805825 3 P39687 1 +ROCK, Rho binding domain [IPR015008] 0.599712230215824 0.4530132545647292 0.6505391972291568 1.0 0.7346514665926648 2 Q13464 1 +NET domain [IPR027353] 0.598848920863306 0.4502122951230143 0.6525573716569664 1.0 0.7357264484367758 2 O60885 1 +Brdt, bromodomain, repeat I [IPR043508] 0.598848920863306 0.4502122951230143 0.6525573716569664 1.0 0.7357264484367758 2 O60885 1 +Brdt, bromodomain, repeat II [IPR043509] 0.598848920863306 0.4502122951230143 0.6525573716569664 1.0 0.7357264484367758 2 O60885 1 +LsmAD domain [IPR009604] 0.593669064748198 0.4335584392556502 0.6646091205045197 1.0 0.7468734416093137 2 Q99700 1 +Ataxin 2, SM domain [IPR025852] 0.593669064748198 0.4335584392556502 0.6646091205045197 1.0 0.7468734416093137 2 Q99700 1 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.3604129976211064 0.4279330685566888 0.6686998506310555 1.0 0.7508590674295009 11 P21266 1 +SMARCC, N-terminal [IPR032450] 0.5905035971222988 0.4235117178730063 0.6719219510031322 1.0 0.7535573282278119 2 Q92922 1 +SMARCC, C-terminal [IPR032451] 0.5905035971222988 0.4235117178730063 0.6719219510031322 1.0 0.7535573282278119 2 Q92922 1 +SMARCC, SWIRM-associated domain [IPR032448] 0.5905035971222988 0.4235117178730063 0.6719219510031322 1.0 0.7535573282278119 2 Q92922 1 +Beta-Casp domain [IPR022712] 0.5766906474820108 0.3808829949769794 0.7032900711671031 1.0 0.7842123985105679 2 Q9UKF6 1 +Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108] 0.5766906474820108 0.3808829949769794 0.7032900711671031 1.0 0.7842123985105679 2 Q9UKF6 1 +Dynamin, GTPase domain [IPR001401] 0.4734812062170024 0.3573093012387204 0.7208602675961808 1.0 0.7993468616172997 4 O60313 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.373260179209296 0.3561474597197257 0.7217301365489059 1.0 0.7999900308734861 8 P98194,P35670,Q9HD20 3 +MRH domain [IPR044865] 0.5736902705814484 0.3502019331177288 0.7261871560987738 1.0 0.8042843301896532 3 P11717,P20645 2 +Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528] 0.5617266187050323 0.3370603370841278 0.7360714160906794 1.0 0.8126228433641101 2 Q99996 1 +FAD dependent oxidoreductase [IPR006076] 0.4638308717423421 0.3262366475638334 0.7442453160630129 1.0 0.8186995106950641 4 Q9H9P8 1 +EB1, C-terminal [IPR004953] 0.5576978417266151 0.3257046342735244 0.744647837630104 1.0 0.8188159489478434 2 Q15691 1 +CID domain [IPR006569] 0.3860969888582704 0.3221542412973538 0.7473358481378585 1.0 0.8214444208922698 7 Q8IWX8,O15042,Q9UPN6,Q5VT52 4 +PDZ domain 6 [IPR041489] 0.5600117758874943 0.3127069791472047 0.7545032927213278 1.0 0.8286227651721159 3 O00233 1 +R3H domain [IPR001374] 0.5514037030739467 0.2900929174311412 0.7717451540175029 1.0 0.8455802402097292 3 O95453 1 +Dbl homology (DH) domain [IPR000219] 0.3863439930855629 0.2581100116664435 0.7963220051208073 1.0 0.8683716847623185 6 Q92974,Q9NZM3,Q14155,Q9H8V3,Q12802 5 +PDZ domain [IPR001478] 0.2842351752551892 0.2567044207569756 0.7974069586149284 1.0 0.868605841087426 26 Q96RT1,Q9NR12,O00233,Q6ZWJ1,Q9NZW5,Q13425,O43464,Q14160,Q00013,Q9Y4G8 10 +Target SNARE coiled-coil homology domain [IPR000727] 0.3361017356650248 0.2518739503664094 0.8011384951753495 1.0 0.8695014733322708 10 O95721,O60499,Q9UNK0,Q5SQN1 4 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.405817972350235 0.2420135155833597 0.8087696905664288 1.0 0.8750311038664615 5 Q05397,P07947,P41240,P07948 4 +Zinc finger, CXXC-type [IPR002857] 0.4326492260572695 0.2337669872312382 0.815165879886437 1.0 0.8798818257671357 4 Q03164 1 +Marvel domain [IPR008253] 0.526962604475878 0.2302989889324035 0.8178594462138256 1.0 0.8817547154492806 3 Q16625 1 +UBX domain [IPR001012] 0.3607052272313918 0.2265827335691468 0.8207482197408078 1.0 0.8838334321048107 7 Q92575 1 +PABP, RNA recognition motif 2 [IPR045305] 0.5107913669064708 0.2086009487969505 0.8347597698370381 1.0 0.8961248404318263 2 Q13310 1 +Peptidase M41 [IPR000642] 0.5093525179856073 0.2054729829850617 0.8372026042199026 1.0 0.8975282870329089 2 Q9Y4W6 1 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.4218255110855185 0.204772504201434 0.8377498702541506 1.0 0.8975891467008756 4 Q8WVV9,Q9UKA9,P14866 3 +Saposin B type domain [IPR008139] 0.5058992805755353 0.1980830363626201 0.8429800968868708 1.0 0.9021423293554724 2 P07602 1 +Adenylate kinase, active site lid domain [IPR007862] 0.5047482014388447 0.1956565872448798 0.8448789659335989 1.0 0.903123914011128 2 P54819 1 +ZU5 domain [IPR000906] 0.5015827338129455 0.1890792161317004 0.8500307307837396 1.0 0.9068746876548592 2 Q12955 1 +WHIM1 domain [IPR028942] 0.413187446012094 0.1828676453108841 0.8549018700777602 1.0 0.910312176471689 4 Q96T23,Q9NRL2,Q9UIF9 3 +GAR domain [IPR003108] 0.4975539568345282 0.1809109192580323 0.8564374979473925 1.0 0.9115956399285784 2 Q03001 1 +Zinc finger C2H2-type [IPR013087] 0.2677731202576514 0.1769516608472704 0.8595463593465202 1.0 0.9141995960679752 30 P52756,Q96JM3,O95785,P98175,Q8ND82 5 +B-box-type zinc finger [IPR000315] 0.3601267646211464 0.1718142535714785 0.8635835594352477 1.0 0.9170798861259268 6 P19474,Q9UPN9,O15344,Q12899,O15164 5 +cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.4920863309352475 0.1701901780644668 0.8648605758062811 1.0 0.91772979208971 2 P10644 1 +Histone-binding protein RBBP4, N-terminal [IPR022052] 0.4890616004605485 0.1514877276778546 0.8795909910119759 1.0 0.9280088437282314 3 Q9BQ67,Q09028 2 +SLC12A transporter, C-terminal [IPR018491] 0.4811510791366863 0.1500127921677162 0.880754522777675 1.0 0.928526540437885 2 Q9BXP2 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.4811510791366863 0.1500127921677162 0.880754522777675 1.0 0.928526540437885 2 Q9BXP2 1 +Methylthiotransferase, N-terminal [IPR013848] 0.4785611510791323 0.1454808684486651 0.8843312198130833 1.0 0.9305200787968394 2 Q5VV42 1 +TRAM domain [IPR002792] 0.4785611510791323 0.1454808684486651 0.8843312198130833 1.0 0.9305200787968394 2 Q5VV42 1 +Complex 1 LYR protein domain [IPR008011] 0.4687769784172616 0.1292105239198247 0.8971910691343963 1.0 0.9393958083501266 2 Q9Y6M9 1 +Ataxin-2, C-terminal [IPR009818] 0.387273250791821 0.1240431949297774 0.9012810745351868 1.0 0.941891618976568 4 Q9H074,Q99700,Q8WWM7 3 +Forkhead-associated (FHA) domain [IPR000253] 0.3070934256055259 0.1228215302931547 0.902248424633734 1.0 0.9424900803375303 9 Q14676,Q9P2P6,Q9BWU0,P46013,Q15058,O60934,Q5SW79,P55196 8 +ELMO domain [IPR006816] 0.4644604316546716 0.1224575078259143 0.9025366964971352 1.0 0.9424900803375303 2 Q96JJ3 1 +B-box, C-terminal [IPR003649] 0.3600230414746578 0.1166033183513989 0.9071744080018168 1.0 0.9469642153878112 5 Q9UPN9,O15344,O15164,Q9BTV5 4 +Stromal interaction molecule, Orai1-activating region [IPR032393] 0.4587050359712182 0.1138544901239343 0.9093531425118976 1.0 0.9469642153878112 2 Q9P246 1 +Methyltransferase domain [IPR025714] 0.4569784172661829 0.1113622990606253 0.9113290550479884 1.0 0.9480845050631164 2 Q7L2J0 1 +Zinc finger, MYND-type [IPR002893] 0.4645350558990497 0.1099857905769449 0.9124206440187692 1.0 0.9488624632599107 3 Q9H7B4 1 +Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187] 0.4509352517985571 0.102958858946691 0.917995623171328 1.0 0.9528649567329316 2 Q8WUM0 1 +Double-stranded RNA-binding domain [IPR014720] 0.27519491770142 0.100885731607162 0.9196411698430133 1.0 0.9542141461529008 14 O15226,Q9UPY3,Q8WYQ5,P19525,Q96SI9,P18583,Q12906,P55265,O95793,Q08211,Q9H9J2,Q9NUL3,Q9NXV6 13 +RecF/RecN/SMC, N-terminal [IPR003395] 0.3321809276865503 0.093953686888474 0.9251459464379932 1.0 0.9588444657036655 6 Q9UQE7,Q9NTJ3,O95347,Q96SB8,Q8IY18 5 +Morc, S5 domain 2-like [IPR041006] 0.4417266187050312 0.0910940855362539 0.927417832163158 1.0 0.960477754885672 2 Q14149 1 +Small-subunit processome, Utp12 [IPR007148] 0.442429476108218 0.0790011732415001 0.937031689870096 1.0 0.9693431274518232 3 Q15061,Q15269 2 +Zinc finger, CW-type [IPR011124] 0.4418537708692954 0.0782739246376933 0.9376101589352404 1.0 0.969378117349345 3 Q14149,Q8NB78 2 +Zinc finger, FYVE-related [IPR017455] 0.3252664938058175 0.0771246982879442 0.9385243451225844 1.0 0.9694338295427892 6 Q9NYA4,Q96T51,Q15075,O14964,Q7Z3T8 5 +FYVE zinc finger [IPR000306] 0.3252664938058175 0.0771246982879442 0.9385243451225844 1.0 0.9694338295427892 6 Q9NYA4,Q96T51,Q15075,O14964,Q7Z3T8 5 +YqgF/RNase H-like domain [IPR006641] 0.4264748201438808 0.0738572091445254 0.9411240049657208 1.0 0.9713920170925168 2 Q7KZ85 1 +HHH domain 9 [IPR041692] 0.4264748201438808 0.0738572091445254 0.9411240049657208 1.0 0.9713920170925168 2 Q7KZ85 1 +SH3 domain [IPR001452] 0.2439835724067254 0.0643767170131881 0.9486702686949968 1.0 0.9773534683083954 39 P46108,Q00013,Q9UQB8 3 +WSTF/Acf1/Cbp146 [IPR013136] 0.4129496402877647 0.0609559789074713 0.9513942675672956 1.0 0.9792405510752716 2 Q9NRL2 1 +SMCs flexible hinge [IPR010935] 0.3320852534562272 0.0584450084189513 0.9533941644855116 1.0 0.9803904224962788 5 A6NHR9,Q9UQE7,O95347,Q9NTJ3 4 +CTLH, C-terminal LisH motif [IPR006595] 0.3446587964296005 0.050581514110937 0.9596589935692432 1.0 0.9835611234786512 4 Q96S59,Q9UL63,Q2TAY7 3 +Protein of unknown function DUF3504 [IPR021893] 0.3426432479124631 0.047818265061788 0.961861079792911 1.0 0.9850599555578606 4 Q2TAL8,Q9UBW7,Q14202 3 +Glycosyltransferase 2-like [IPR001173] 0.3406276993953299 0.0451172675971394 0.9640138378849584 1.0 0.9864879071470628 4 Q10472,Q10471,Q9Y673 3 +CAP Gly-rich domain [IPR000938] 0.4107656879677418 0.0447235383818059 0.9643276715517302 1.0 0.9864879071470628 3 Q14203,Q99426 2 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.4018422567645278 0.0370598704544666 0.9704372687705644 1.0 0.99075467625128 3 Q9UPN9,O15344 2 +L27 domain, C-terminal [IPR014775] 0.3340984981970415 0.036790050214603 0.9706524074577758 1.0 0.99075467625128 4 Q9NZW5,O14936 2 +L27 domain [IPR004172] 0.3340984981970415 0.036790050214603 0.9706524074577758 1.0 0.99075467625128 4 Q9NZW5,O14936 2 +Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.3741007194244556 0.034779341399366 0.9722556938393684 1.0 0.992024293898949 2 Q13243 1 +GTPase effector domain [IPR020850] 0.3865860679332 0.0258038747801776 0.9794137712516195 1.0 0.9962139211125948 3 O00429,Q9UQ16 2 +Dynamin GTPase effector [IPR003130] 0.3865860679332 0.0258038747801776 0.9794137712516195 1.0 0.9962139211125948 3 O00429,Q9UQ16 2 +Dynamin stalk domain [IPR000375] 0.3865860679332 0.0258038747801776 0.9794137712516195 1.0 0.9962139211125948 3 O00429,Q9UQ16 2 +Sterile alpha motif domain [IPR001660] 0.2688929208362646 0.0255574113777783 0.979610355760718 1.0 0.9962139211125948 10 Q9Y3Z3 1 +Ribosome receptor lysine/proline rich [IPR007794] 0.3435971223021533 0.0231873032923793 0.981500866390928 1.0 0.9974666748935932 2 Q86UP2 1 +SGS domain [IPR007699] 0.3433093525179805 0.0231068617667028 0.9815650322503622 1.0 0.9974666748935932 2 Q9HB71 1 +Citron homology (CNH) domain [IPR001180] 0.339568345323736 0.0221032098298016 0.9823656260287454 1.0 0.9978089923764726 2 Q8WUH2 1 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.2728870261119971 0.0213249169689709 0.9829864674897206 1.0 0.9978089923764726 8 O60313,Q8IWA4 2 +Dynamin, N-terminal [IPR045063] 0.2728870261119971 0.0213249169689709 0.9829864674897206 1.0 0.9978089923764726 8 O60313,Q8IWA4 2 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.3785261945883545 0.0207336780947894 0.98345810355465 1.0 0.9979207227245714 3 Q9NUQ9,Q96F07 2 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.2670126874279043 0.0142663028352683 0.9886175233369512 1.0 1.0 9 Q13546,P41240,Q13418,Q15375,Q05397,P07947,Q9UHY1,P07948 8 +Reticulon [IPR003388] 0.309818600633455 0.0112299323567636 0.99103999868043 1.0 1.0 4 Q9NQC3,O95197,Q16799 3 +HR1 rho-binding domain [IPR011072] 0.3015552995391695 0.0112209580474021 0.9910471586921804 1.0 1.0 5 O75116,Q13464,Q5T0N5,Q16513 4 +Initiation factor eIF-4 gamma, MA3 [IPR003891] 0.2918467300489816 0.0098943303328239 0.9921055953956044 1.0 1.0 6 O43432,Q5C9Z4,Q9HCG8,Q53EL6,Q04637 5 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.3534830166954407 0.00838445785291 0.99331024890917 1.0 1.0 3 Q96EY1,P31689 2 +Zinc finger, MYM-type [IPR010507] 0.3425446171560051 0.0043984453602761 0.9964905596712978 1.0 1.0 3 Q14202,Q9UBW7 2 +Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.329324254909213 0.0005333277793306 0.999574466019198 1.0 1.0 3 P42356 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..15614a260a936c59e110b5b89050a387b6a871ea --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3, C-terminal [IPR007177]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AF-9, ANC1 homology domain [IPR040930]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "APPL1, BAR domain [IPR037929]", "ARF GTPase-activating protein GIT1, C-terminal [IPR022018]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATF7-interacting protein , protein binding domain [IPR031870]", "ATM, catalytic domain [IPR044107]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adaptor protein ClpS, core [IPR003769]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 1 [IPR041880]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 2 [IPR041882]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arf GTPase-activating protein GIT1/2, coiled-coil domain [IPR032352]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCL10, CARD domain [IPR042143]", "BCS1, N-terminal [IPR014851]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBP/p300-type histone acetyltransferase domain [IPR031162]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CREB-binding protein/p300, atypical RING domain [IPR010303]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbohydrate kinase, FGGY, N-terminal [IPR018484]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class V myosin, motor domain [IPR036103]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coactivator CBP, KIX domain [IPR003101]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDB1- and CUL4-associated factor 15, WD40 repeat-containing domain [IPR032734]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4706 [IPR031600]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase AMFR, Ube2g2-binding region [IPR040675]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF114, RING finger, HC subclass [IPR042716]", "E3 ubiquitin-protein ligase RNF31, PUB domain [IPR040641]", "E3 ubiquitin-protein ligase RNF31, UBA-like domain [IPR032065]", "E3 ubiquitin-protein ligase UBR-like, C-terminal [IPR044046]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERCC4 domain [IPR006166]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "F-box/LRR-repeat protein 18, LRR domain [IPR045627]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain [IPR002938]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAK1/PYK2, FERM domain C-lobe [IPR041784]", "FAM192A/Fyv6, N-terminal [IPR019331]", "FAM69, protein-kinase domain [IPR022049]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FNBP1L, F-BAR domain [IPR035494]", "FNBP1L, SH3 domain [IPR035493]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferritin-like diiron domain [IPR009040]", "Ferritin/DPS protein domain [IPR008331]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "Fibronectin type III and SPRY containing 1, PRY/SPRY domain [IPR035742]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focal adhesion kinase, N-terminal [IPR041390]", "Focal adhesion kinase, targeting (FAT) domain [IPR005189]", "Follistatin-like, N-terminal [IPR003645]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GA-binding protein alpha subunit, N-terminal [IPR024668]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GIT, Spa2 homology (SHD) domain [IPR013724]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gasdermin, PUB domain [IPR041263]", "Gasdermin, pore forming domain [IPR040460]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Germinal-centre associated nuclear protein, CID domain [IPR031910]", "Germinal-centre associated nuclear protein, MCM3AP domain [IPR031907]", "Germinal-centre associated nuclear protein, nucleoporin homology domain [IPR031908]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAT, C-terminal dimerisation domain [IPR008906]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HEPN domain [IPR007842]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase Helix-turn-helix domain [IPR029491]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox protein Hox1A3 N-terminal [IPR022067]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Knl1, C-terminal RWD domain [IPR040850]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L1 transposable element, RRM domain [IPR043636]", "L1 transposable element, dsRBD-like domain [IPR035300]", "L1 transposable element, trimerization domain [IPR035301]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIM interaction domain [IPR041363]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM7, LYR domain [IPR045298]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Liprin-beta, SAM domain repeat 1 [IPR037617]", "Liprin-beta, SAM domain repeat 2 [IPR037618]", "Liprin-beta, SAM domain repeat 3 [IPR037619]", "Listerin, zinc finger, RING-type [IPR039804]", "Little elongation complex subunit 2 , C-terminal [IPR019535]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "LysM domain [IPR018392]", "Lysine-specific demethylase 4, Tudor domain [IPR040477]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MCM3AP, RNA recognition motif [IPR034265]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MGA, conserved domain [IPR032060]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MMS22-like, C-terminal [IPR029424]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTF2, PHD domain 1 [IPR042014]", "MTF2, PHD domain 2 [IPR042015]", "MTMR14, PH-GRAM domain [IPR039803]", "MTMR4, PH-GRAM domain [IPR035997]", "MTMR6, PH-GRAM domain [IPR035998]", "MUN domain [IPR010439]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Mammalian uncoordinated homology 13, domain 2 [IPR014772]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Munc13 homology 1 [IPR014770]", "Muskelin, N-terminal [IPR010565]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin 5a, cargo-binding domain [IPR037988]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase chain 4, N-terminal [IPR000260]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nas2, N-terminal [IPR040815]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear receptor coactivator, CREB-bp-like, interlocking [IPR014744]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain [IPR019601]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PBX [IPR005542]", "PCAF, N-terminal [IPR009464]", "PCNA-associated factor, histone-like domain [IPR031444]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUB domain [IPR018997]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Par3/HAL, N-terminal [IPR021922]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain-containing protein 2 [IPR033903]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Pointed domain [IPR003118]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb protein, VEFS-Box [IPR019135]", "Polycomb-like MTF2 factor 2, C-terminal domain [IPR025894]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-mRNA-splicing factor SLU7 domain [IPR021715]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Programmed cell death protein 2, C-terminal [IPR007320]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 3,4-dihydroxylase TPA1/OFD1, N-terminal domain [IPR039558]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein MMS22-like, N-terminal [IPR029425]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein Unc-13, C2B domain [IPR037302]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Putative zinc-finger domain [IPR019607]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAD51 interacting motif [IPR031419]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RFX1 transcription activation region [IPR007668]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger and SPRY domain-containing protein 1, SPRY domain [IPR035774]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNF31, C-terminal [IPR041031]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Right handed beta helix domain [IPR039448]", "Ring finger protein 123, SPRY domain [IPR035773]", "RmlD-like substrate binding domain [IPR029903]", "Rpn11/EIF3F, C-terminal [IPR024969]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCAN domain [IPR003309]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD3, SET domain [IPR044428]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIR2-like domain [IPR039444]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX8/Mvp1, PX domain [IPR035704]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Selenoprotein F/M domain [IPR014912]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm4 [IPR034101]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 8/Mvp1, BAR domain [IPR045734]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Sphingolipid delta4-desaturase, N-terminal [IPR013866]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Star-PAP, RNA recognition motif [IPR034388]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 1, SAM domain [IPR037609]", "Stromal interaction molecule 2, SAM domain [IPR037610]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "Syntrophin, split Pleckstrin homology (PH) domain [IPR041428]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBC1D8B, PH-GRAM domain 1 [IPR036012]", "TBC1D8B, PH-GRAM domain 2 [IPR036015]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TROVE domain [IPR008858]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomere-length maintenance and DNA damage repair [IPR021668]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 38 [IPR033840]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Unconventional myosin-Ie/If, SH3 domain [IPR035507]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting protein 11, C-terminal [IPR024763]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain [IPR030383]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WASP family, EVH1 domain [IPR033927]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger C2HC RNF-type [IPR034734]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, BED-type [IPR003656]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, HIT-type [IPR007529]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TAZ-type [IPR000197]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APC", "APEH", "APEX1", "APEX2", "APMAP", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC9", "ARMCX3", "ARMT1", "ARSA", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD5", "ATF7IP", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7B", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCL10", "BCOR", "BCS1L", "BEND3", "BIRC6", "BLVRA", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD7", "BRIX1", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C11orf58", "C1orf198", "C1orf35", "C2CD2", "C2CD5", "C3orf58", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC7", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CENPB", "CENPE", "CENPF", "CENPV", "CEP170", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNPY2", "COA3", "COASY", "COIL", "COMMD2", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "CPD", "CPNE3", "CPNE8", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCP1A", "DCTN1", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC8", "EMD", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM118B", "FAM129B", "FAM192A", "FAM208A", "FAM208B", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBXL18", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLVCR1", "FMR1", "FNBP1L", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FSD1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GAK", "GALK1", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDE1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA4", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS14", "INTS3", "INTS5", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "KARS", "KAT2A", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KIN", "KMT2A", "KNL1", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCOR", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRSAM1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MEPCE", "METAP2", "METTL13", "MFAP1", "MFN1", "MFN2", "MFSD10", "MGA", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MLEC", "MLLT1", "MMAB", "MMS19", "MMS22L", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD1", "MOSPD2", "MOV10", "MPHOSPH8", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL2", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS10", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MUT", "MVD", "MYADM", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA20", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP2", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCOR1", "NCSTN", "ND4", "NDC80", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OCRL", "OFD1", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PBX2", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD2L", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYCR3", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RAC3", "RACGAP1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAI1", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP4", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDX", "RECQL", "RECQL4", "RELA", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOK2", "RIOX2", "RIPK1", "RMND1", "RNASEH2A", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RPUSD3", "RRBP1", "RRM1", "RRP12", "RRP7A", "RSF1", "RSL24D1", "RSPRY1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SC5D", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCO2", "SCP2", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SELENOF", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHPK", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A4", "SLC2A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD7", "STARD9", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIM2", "STIP1", "STK26", "STK4", "STOML2", "STRBP", "STRIP1", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAOK1", "TAOK2", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TECR", "TEDC1", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "TIAL1", "TIMELESS", "TIMM13", "TIMM44", "TIMM50", "TJP1", "TJP2", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM104", "TMEM201", "TMEM205", "TMEM97", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSR1", "TSR3", "TST", "TSTA3", "TTC4", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TUT1", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "URB2", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS11", "VPS13A", "VPS16", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "VTA1", "WAPL", "WARS", "WASHC4", "WASL", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WDR62", "WFS1", "WIZ", "WNK1", "WRN", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YBX1", "YES1", "YIPF4", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBED1", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF106", "ZNF148", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF638", "ZNF644", "ZNF687", "ZNHIT2", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["ABCB1", "ACBD3", "ACOX1", "ACTN1", "ADAR", "ADD1", "AFDN", "AFG3L2", "AK2", "AKAP1", "AKAP13", "AKAP8", "AKAP9", "AKT1", "ALDH1A2", "ALDH1B1", "ALG5", "ALYREF", "ANK3", "ANKLE2", "ANP32A", "ARHGEF2", "ARHGEF7", "ATAD2", "ATP13A1", "ATP2C1", "ATP7B", "ATXN2", "ATXN2L", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAZ1A", "BAZ2A", "BRCA1", "BRD4", "BRD7", "BSDC1", "C11orf58", "CACYBP", "CALM3", "CALU", "CASK", "CBL", "CBX3", "CBX5", "CD2BP2", "CDKAL1", "CDKN2AIP", "CEP170", "CERS2", "CETN2", "CHAMP1", "CHERP", "CIRBP", "CIZ1", "CLK3", "COMMD2", "CPNE8", "CPSF3", "CPSF7", "CRK", "CSK", "CSTF2", "CWC22", "CYB5B", "CYB5D2", "CYFIP2", "DAZAP1", "DCTN1", "DCUN1D4", "DEGS1", "DGCR8", "DHCR24", "DHX9", "DICER1", "DNAJA1", "DNAJA3", "DNAJB6", "DNAJC1", "DNAJC16", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM3", "DST", "ECI2", "ECT2", "EEA1", "EIF2AK2", "EIF4B", "EIF4G1", "EIF4G3", "EIF4H", "ELMO2", "ELOA", "EPHA7", "EPHX1", "EPHX2", "ERBIN", "EWSR1", "FAM208A", "FAM49B", "FBXO22", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FLVCR1", "FNBP1L", "FSD1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "GAK", "GALNT1", "GALNT2", "GAPVD1", "GATAD2B", "GCC2", "GINS4", "GNPAT", "GPATCH4", "GRWD1", "GSTM3", "GTF2B", "HDGF", "HDGFL2", "HDGFL3", "HGS", "HLA-C", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPUL1", "HNRNPUL2", "HTRA2", "IGF2R", "ILF3", "ILK", "INA", "INPP4A", "IRF2BP2", "ITPRIP", "ITSN2", "IWS1", "KAT2A", "KCTD12", "KDM1B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF14", "KMT2A", "KTN1", "L2HGDH", "LCLAT1", "LEMD3", "LMNB1", "LMNB2", "LNPEP", "LRSAM1", "LTA4H", "LYN", "M6PR", "MAPRE1", "MARK2", "MATR3", "MBD1", "MBD3", "MCM3AP", "MCM6", "MDC1", "MECP2", "MEPCE", "MFN1", "MFSD10", "MICU2", "MID1", "MKI67", "MKLN1", "MORC3", "MPP1", "MPP6", "MRPL44", "MSI2", "MTMR2", "MTMR4", "MTX1", "MYEF2", "NBN", "NCL", "NDUFB9", "NEDD4", "NEDD4L", "NEFM", "NELFE", "NENF", "NES", "NKRF", "NLN", "NOL8", "NOM1", "NONO", "NPC1", "NPEPPS", "NRBP1", "NSD1", "NSD2", "NUCB1", "NUDC", "NUP133", "NUP153", "NUPL2", "OCLN", "OPA1", "OSBPL3", "OSBPL6", "P4HA1", "P4HA2", "PABPC4", "PAIP1", "PARN", "PARP1", "PARP2", "PBRM1", "PDCD4", "PDK1", "PDLIM7", "PEF1", "PGRMC2", "PHF14", "PHF3", "PHF8", "PHRF1", "PI4KA", "PINX1", "PITRM1", "PKN2", "PMPCA", "PNO1", "POGZ", "PRKAR1A", "PRKCB", "PRPF40A", "PRRC2B", "PRRC2C", "PSAP", "PSIP1", "PSMD9", "PSME2", "PSME3", "PSPC1", "PTBP2", "PTK2", "PUF60", "PWP2", "QKI", "QRICH1", "RAB11FIP1", "RACGAP1", "RAD18", "RAI1", "RANBP3", "RANBP9", "RAPGEF2", "RBBP4", "RBM10", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM3", "RBM4", "RBM5", "RBM6", "RBMX", "RBMXL1", "RCN2", "REPS1", "RIPK1", "RNF123", "RNF20", "RNF219", "RNF31", "RNF40", "ROCK1", "ROCK2", "RPRD2", "RPS6KA1", "RPS6KA3", "RSF1", "RSPRY1", "RTN1", "RTN3", "RTN4", "RUFY1", "SAFB", "SAFB2", "SAMHD1", "SARNP", "SCAF11", "SCAF8", "SCRIB", "SDF4", "SEC63", "SETD1A", "SETD7", "SF1", "SF3A3", "SF3B4", "SFPQ", "SIRT2", "SLC12A9", "SLC16A1", "SLC25A13", "SLC4A1AP", "SMARCC1", "SMARCE1", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMNDC1", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SNTB2", "SNX1", "SON", "SPTAN1", "SQSTM1", "SRSF1", "SRSF10", "SRSF12", "SRSF2", "SRSF5", "SRSF9", "STARD9", "STAU1", "STAU2", "STIM2", "STRBP", "STX10", "STX8", "STXBP4", "SUGP1", "SUPT6H", "SYNCRIP", "TAF15", "TARDBP", "TBC1D8B", "TBCB", "TCEA1", "TFIP11", "TGFBRAP1", "TIAL1", "TJP2", "TMED10", "TMED2", "TMED7", "TMED9", "TMEM97", "TMPO", "TRA2A", "TRA2B", "TRAM1", "TRIM21", "TRIM24", "TRIM26", "TRIM33", "TUBB", "TUBB4B", "U2SURP", "UBAC1", "UBAP2L", "UBQLN4", "UBXN4", "UNC119B", "UNC13B", "UQCRC2", "USP11", "USP15", "VIM", "VPS11", "WBP2", "WDR43", "WIZ", "WRN", "XRCC6", "YES1", "YTHDC1", "YTHDF2", "YTHDF3", "ZBTB10", "ZC3H14", "ZC3H18", "ZC3H7B", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM3", "ZMYND8", "ZNF280C", "ZNF318", "ZNF638"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..249314cfd73091f1962317d23a0b51c7b428aecf --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a62aec38208bdb64555db88adc2dee33eaf83eb18f39833ab635f8034459f55b +size 528131 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fbf4453ff2ec8eae01839115634d3ef87c9c4f71 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Major facilitator superfamily [IPR011701] 4 5 2.3036058913130133 0.021244776845795 1.900485436893204 4.145631067961165 1.0239318262629833 0.2378354197978781 1.3191273068698348 1.552684909115802 1.329586452483978 0.2573287434106264 0.0769843908651827 1.0 0.2070995190727305 0.0195244436529747 0.0053032680205866 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 3 5 2.248282194745712 0.0245582013424412 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 8.72823867368061e-06 0.0370595951599339 0.002465796513642 2.1797401302891516e-05 0.0003337445501144 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4c93c24c76e600fd8bd64a6f826abcabcba68828 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 2657, + "title": "Average number of proteins per term", + "value": 1.2860368837034248 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0be78e3ffcc16cdde33ea4b0d51d89294e112d4c --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d9643e0020c5ffbafaec100bb7e2dfda182ac1f3 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,123 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Major facilitator superfamily [IPR011701] 0.8876728110599104 2.3036058913130133 0.021244776845795 1.0 0.0715429303919866 5 Q9Y5Y0,Q9H2V7,Q14728,P53985 4 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.8745600833761595 2.2482821947457117 0.0245582013424412 1.0 0.0774034886914192 5 P55786,Q9UIQ6,P09960 3 +Nucleosome assembly protein (NAP) [IPR002164] 0.923417513459042 2.191758926949725 0.0283969183061993 1.0 0.0843966576505277 4 P55209,Q01105 2 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.999136690647482 2.0495317483337203 0.0404101466359037 1.0 0.1051613708242861 2 Q99595 1 +Ribosomal protein S6 kinase II [IPR016239] 0.9792805755395684 1.968407005521582 0.0490212264909422 1.0 0.1195088536383667 2 P51812 1 +Oxysterol-binding protein [IPR000648] 0.756567136302336 1.9494078831183297 0.0512467338612703 1.0 0.1240017582749252 6 Q9BZF3 1 +Epoxide hydrolase-like [IPR000639] 0.9784569201852896 1.8296974520944111 0.0672951921171303 1.0 0.1490612529563661 3 P07099 1 +Haem oxygenase [IPR002051] 0.9381294964028772 1.7989635823104515 0.0720244416222084 1.0 0.1558038748186521 2 P30519 1 +Haem oxygenase-like [IPR016053] 0.9381294964028772 1.7989635823104515 0.0720244416222084 1.0 0.1558038748186521 2 P30519 1 +Prolyl 4-hydroxylase [IPR045054] 0.9378417266187048 1.7977730582301477 0.072212978450695 1.0 0.1558650558436204 2 O15460 1 +Aminopeptidase N-type [IPR034016] 0.964306275187103 1.775708798595394 0.0757809264280167 1.0 0.1610799372153923 3 P55786,Q9UIQ6 2 +Palmitoyl protein thioesterase [IPR002472] 0.9274820143884888 1.754868295765419 0.0792818382701106 1.0 0.1658675939241605 2 Q9UMR5 1 +Eukaryotic porin/Tom40 [IPR027246] 0.8156951058016121 1.7496583321457952 0.0801772877283402 1.0 0.1672143277034536 4 P21796,P45880 2 +HnRNP R/Q splicing factor [IPR006535] 0.9225899280575536 1.7345780435416105 0.0828155712910834 1.0 0.1703103505575918 2 O60506 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.9526981940913845 1.7312906015481544 0.0833999468742452 1.0 0.1711147944748027 3 O43823 1 +HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380] 0.8047107533917112 1.7036488647700272 0.08844670663037 1.0 0.1784380406354541 4 Q9H857,P49902 2 +Tropomodulin [IPR004934] 0.9125179856115104 1.6927488643326023 0.0905032798474994 1.0 0.1810601809065658 2 Q9NYL9 1 +HAD hydrolase, subfamily IA [IPR006439] 0.9084892086330928 1.6759978637547364 0.0937386110484554 1.0 0.1851773156548299 2 P34913 1 +Haloacid dehalogenase-like hydrolase [IPR041492] 0.9084892086330928 1.6759978637547364 0.0937386110484554 1.0 0.1851773156548299 2 P34913 1 +CD36 family [IPR002159] 0.9058992805755388 1.6652239348438291 0.0958680874888517 1.0 0.187157610916884 2 Q8WTV0 1 +Cytochrome P450 [IPR001128] 0.8989928057553951 1.636474007911563 0.1017404212279591 1.0 0.195174004310393 2 Q6UW02 1 +KH domain-containing BBP-like [IPR045071] 0.7886553412035794 1.6361377900013665 0.1018107527189329 1.0 0.195174004310393 4 Q07666,O75525,Q96PU8 3 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9227439894623686 1.6161925143699285 0.1060526967300399 1.0 0.200985745514776 3 Q9H3G5 1 +THRAP3/BCLAF1 family [IPR029199] 0.8889208633093517 1.5945015687954522 0.1108237396447151 1.0 0.2072193358451851 2 Q9NYF8 1 +AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752] 0.8869064748201432 1.5861013691943753 0.1127163163362421 1.0 0.2097249667404729 2 O00400 1 +Tropomyosin [IPR000533] 0.8823021582733805 1.5668946447111327 0.1171393196400272 1.0 0.2159883221953867 2 P67936 1 +Acyl-CoA oxidase [IPR012258] 0.8610071942446034 1.4779790822543055 0.1394133771978714 1.0 0.2449876608563123 2 Q15067 1 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.8610071942446034 1.4779790822543055 0.1394133771978714 1.0 0.2449876608563123 2 Q15067 1 +Nucleobindin [IPR040250] 0.8584172661870494 1.4671590969195845 0.1423327809567913 1.0 0.2491292483545419 2 Q02818 1 +Sirtuin family [IPR003000] 0.8831773934259888 1.463353823003924 0.1433705871646775 1.0 0.249957775653903 3 Q8IXJ6 1 +TAF15/EWS/TLS family [IPR034870] 0.8704663212435183 1.4141343075450072 0.1573224716533017 1.0 0.2667554608697017 3 Q92804,P35637 2 +E3 ubiquitin ligase Bre1 [IPR013956] 0.8437410071942436 1.4058430889883389 0.1597707238047481 1.0 0.2685077882031725 2 O75150 1 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.8425899280575528 1.4010345952636425 0.1612037281338352 1.0 0.2702323694962776 2 Q9NPH0 1 +Porin, eukaryotic type [IPR001925] 0.8667242371905534 1.3996389750187417 0.1616214565022136 1.0 0.2703603218412767 3 P21796,P45880 2 +Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284] 0.8402877697841716 1.3914182319549702 0.1640986391265619 1.0 0.2731892757890195 2 O15228 1 +Polyprenyl synthetase [IPR000092] 0.7227478984055149 1.35647574697048 0.1749478469299301 1.0 0.2846518244291637 4 O95749,Q5T2R2 2 +Beta tubulin [IPR002453] 0.6570109046895831 1.287713168972308 0.1978458277201431 1.0 0.3099294254745283 5 P07437,P68371 2 +Tubulin [IPR000217] 0.6570109046895831 1.287713168972308 0.1978458277201431 1.0 0.3099294254745283 5 P07437,P68371 2 +YTH domain containing protein [IPR045168] 0.7063057875036124 1.2863258812053535 0.198329353650599 1.0 0.3100611492424708 4 Q9Y5A9,Q7Z739,Q96MU7 3 +Peptidase A22B, signal peptide peptidase [IPR007369] 0.8135251798561137 1.2797535379890668 0.2006318290044597 1.0 0.3118699909906129 2 Q8TCT9 1 +Presenilin/signal peptide peptidase [IPR006639] 0.8135251798561137 1.2797535379890668 0.2006318290044597 1.0 0.3118699909906129 2 Q8TCT9 1 +Purine 5'-nucleotidase [IPR016695] 0.8294959160212478 1.2554629828773334 0.2093107378394689 1.0 0.3210962069511946 3 P49902 1 +Sister chromatid cohesion protein Pds5 [IPR039776] 0.8051798561151063 1.2450131772261464 0.2131269065395822 1.0 0.3257478810286001 2 Q29RF7 1 +Proteasome B-type subunit [IPR023333] 0.5781451586588122 1.2334233484396264 0.217417858362968 1.0 0.329725599126944 7 P20618,P28072,P49721,P28070 4 +Vacuolar protein sorting-associated protein 9-like [IPR045046] 0.7948201438848905 1.2019687745058525 0.2293756263319393 1.0 0.3408562858858852 2 Q14C86 1 +SAC3/GANP/THP3 [IPR045107] 0.7902158273381279 1.1828727108353447 0.2368595983274828 1.0 0.3484695197985171 2 O60318 1 +Sulfotransferase [IPR005331] 0.7810071942446026 1.1447565849619958 0.252310004268947 1.0 0.3632119523330194 2 Q8NCH0 1 +Mitochondrial carrier protein [IPR002067] 0.5033635708989835 1.1273181468762972 0.2596079925765322 1.0 0.3700420086581739 10 Q9BQT8 1 +DNA helicase, ATP-dependent, RecQ type [IPR004589] 0.7957722808500893 1.1253348122837767 0.2604471831857293 1.0 0.3706524722680679 3 Q14191 1 +Peptidase M3A/M3B [IPR045090] 0.7880924369843243 1.0958337871362347 0.2731515195347074 1.0 0.3817798986868583 3 Q9BYT8 1 +PDK/BCKDK protein kinase [IPR039028] 0.7689208633093507 1.0949103435532623 0.2735559170653947 1.0 0.3821440965524467 2 Q15118 1 +Nuclear pore complex protein [IPR026054] 0.7686330935251782 1.09372636656218 0.274075006770186 1.0 0.3823221378625716 2 P35658 1 +Calponin/LIMCH1 [IPR001997] 0.7666187050359694 1.0854425248097035 0.2777257066277152 1.0 0.3861322993448052 2 Q99439 1 +Mitochondrial carrier UCP-like [IPR002030] 0.758273381294962 1.0512025972951138 0.2931655505449337 1.0 0.4015123380571889 2 Q9UBX3 1 +Proteasome activator PA28 [IPR009077] 0.7748992515831848 1.0453188512054623 0.295875627865525 1.0 0.40397818254815 3 P61289,Q9UL46 2 +Protein PRRC2 [IPR033184] 0.7714450201496785 1.0321326078412163 0.3020100002094716 1.0 0.4100360605807696 3 Q9Y520,Q5JSZ5 2 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.747338129496401 1.0065507129279094 0.3141507296911658 1.0 0.419981316815576 2 P35610 1 +Defective-in-cullin neddylation protein [IPR014764] 0.7467625899280557 1.004208013833136 0.3152783602059683 1.0 0.4209520618428431 2 Q92564 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.7602187679907806 0.9894086018248756 0.3224632676576162 1.0 0.4283924510831431 3 P51114,P51116 2 +Ran binding protein RanBP1-like [IPR045255] 0.623054984847691 0.932881481829343 0.3508811645899099 1.0 0.4549981719450418 4 Q9H6Z4 1 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.7182733812949618 0.8893525894357983 0.3738136164330994 1.0 0.4753571768524313 2 Q13868 1 +Tricarboxylate/iron carrier [IPR004686] 0.7336199801454689 0.8891608589041328 0.37391663516055 1.0 0.4753571768524313 3 Q96NB2 1 +Mini-chromosome maintenance protein [IPR031327] 0.5075616128929783 0.8797267466479303 0.3790073563272482 1.0 0.4790782805715978 7 Q14566 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.7148201438848898 0.8755996999449271 0.3812476885861429 1.0 0.4803106252126039 2 O96005 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.7148201438848898 0.8755996999449271 0.3812476885861429 1.0 0.4803106252126039 2 O96005 1 +Tumour protein D52 [IPR007327] 0.7139568345323717 0.8721679548828049 0.3831167585390305 1.0 0.4817516457350705 2 P55327 1 +Glutathione Transferase family [IPR040079] 0.4776083205916934 0.8706164368062709 0.3839636186972386 1.0 0.4823599692097224 8 P21266,Q9H7Z7 2 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.7231557543815936 0.8501879048658801 0.3952206251629482 1.0 0.4895284144981301 3 Q9BTT0 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.5206810603664824 0.8300748834459388 0.4064964466979517 1.0 0.4991040013292319 6 Q9BVK6,Q15363,P49755,Q9Y3B3 4 +Prefoldin alpha-like [IPR004127] 0.698417266187048 0.8108739067047215 0.4174380863220865 1.0 0.5073801442624812 2 Q99471 1 +Enoyl-CoA hydratase/isomerase [IPR001753] 0.4882050468028585 0.7843481767198585 0.4328358379243906 1.0 0.5201469115174608 7 Q13011 1 +Molecular chaperone regulator BAG [IPR039773] 0.7011049925453509 0.769144958321151 0.4418072613808868 1.0 0.528537547721304 3 Q9UL15 1 +FAM98 [IPR018797] 0.6866187050359686 0.7650045727607767 0.4442688216864161 1.0 0.5302885261549001 2 Q52LJ0 1 +CPSF6/7 family [IPR034772] 0.683741007194242 0.7539139795488413 0.4509008757709642 1.0 0.5346022431608444 2 Q8N684 1 +Torsin-1A-interacting protein 1/2 [IPR008662] 0.6756834532374074 0.7230784776436112 0.4696316711604456 1.0 0.5496966300763454 2 Q8NFQ8 1 +Snf7 family [IPR005024] 0.4731078732052527 0.7109851898717923 0.4770934133948159 1.0 0.5531720254320782 7 Q9HD42 1 +Nonaspanin (TM9SF) [IPR004240] 0.6798904683166617 0.6928533851237212 0.4884015658248883 1.0 0.5620108100462228 3 Q99805 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.674726540011505 0.674574225847728 0.4999463127634622 1.0 0.5701104519367035 3 P28072,Q99436 2 +Prenyltransferase subunit beta [IPR045089] 0.6572661870503569 0.6539226651952786 0.5131616307727549 1.0 0.5792142960761298 2 P49356 1 +Transcriptional repressor p66 [IPR040386] 0.6423021582733783 0.5992709763763406 0.5489921989479927 1.0 0.6067233606018122 2 Q8WXI9 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.6351079136690616 0.5735457305011682 0.5662752448636919 1.0 0.616889432391484 2 P07910 1 +H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504] 0.626187050359709 0.5421845509202626 0.5876913769180903 1.0 0.627692483937048 2 Q96HR8 1 +Translin family [IPR002848] 0.6043165467625866 0.4680711689884868 0.6397336961077147 1.0 0.6721124675991292 2 Q15631 1 +Rho-associated protein kinase 1/2 [IPR020684] 0.599712230215824 0.4530132545647292 0.6505391972291568 1.0 0.6829247914017659 2 Q13464 1 +Ataxin2-like [IPR045117] 0.593669064748198 0.4335584392556502 0.6646091205045197 1.0 0.6957708562570957 2 Q99700 1 +Kinesin-like protein [IPR027640] 0.3487890838825727 0.3693391824357376 0.711874923507102 1.0 0.7420367484340409 11 O95235,Q86Y91 2 +Dynamin [IPR022812] 0.4734812062170024 0.3573093012387204 0.7208602675961808 1.0 0.7499317662502163 4 O60313 1 +P-type ATPase [IPR001757] 0.373260179209296 0.3561474597197257 0.7217301365489059 1.0 0.7505428465011519 8 P98194,P35670,Q9HD20 3 +Cell-cycle alteration and expression-elevated protein in tumour [IPR032337] 0.5739781232009072 0.3510108403986985 0.725580215755308 1.0 0.7542514214639487 3 Q9NQG5,Q5VT52 2 +Erlin1/2 [IPR033294] 0.5620143884892048 0.3378788111353143 0.7354545157679775 1.0 0.7628974723880727 2 O94905 1 +A-kinase anchor protein 9/Pericentrin [IPR028745] 0.5617266187050323 0.3370603370841278 0.7360714160906794 1.0 0.7630674024787105 2 Q99996 1 +Microtubule-associated protein RP/EB [IPR027328] 0.5576978417266151 0.3257046342735244 0.744647837630104 1.0 0.770755475100579 2 Q15691 1 +Protein arginine N-methyltransferase [IPR025799] 0.428671920245777 0.3170438685461339 0.7512103156587031 1.0 0.7766403924922857 5 Q6P2P2 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.5107913669064708 0.2086009487969505 0.8347597698370381 1.0 0.8576785415533683 2 Q13310 1 +Peptidase, FtsH [IPR005936] 0.5093525179856073 0.2054729829850617 0.8372026042199026 1.0 0.8596933724232495 2 Q9Y4W6 1 +HnRNP-L/PTB [IPR006536] 0.4218255110855185 0.204772504201434 0.8377498702541506 1.0 0.8597533430920349 4 Q8WVV9,Q9UKA9,P14866 3 +Adenylate kinase subfamily [IPR006259] 0.5047482014388447 0.1956565872448798 0.8448789659335989 1.0 0.8664003907701939 2 P54819 1 +Taxilin family [IPR026183] 0.5021582733812909 0.1902646832706223 0.8491017267762198 1.0 0.8693885503061333 2 Q9NUQ3 1 +Tight junction protein ZO [IPR005417] 0.5015827338129453 0.1890792161316998 0.85003073078374 1.0 0.8700044883252686 2 Q9UDY2 1 +Smooth muscle protein/calponin [IPR003096] 0.5059962808985743 0.1845341257869059 0.8535944583126609 1.0 0.8729793978971285 3 Q99439 1 +Pyridoxal phosphate-dependent decarboxylase [IPR002129] 0.4935251798561108 0.1729706250864468 0.8626745173476829 1.0 0.8812480555912316 2 O95470 1 +cAMP-dependent protein kinase regulatory subunit [IPR012198] 0.4920863309352475 0.1701901780644668 0.8648605758062811 1.0 0.8831416410135622 2 P10644 1 +SLC12A transporter family [IPR004842] 0.4811510791366863 0.1500127921677162 0.880754522777675 1.0 0.8983358030788032 2 Q9BXP2 1 +Methylthiotransferase [IPR005839] 0.4785611510791323 0.1454808684486651 0.8843312198130833 1.0 0.9016377786045134 2 Q5VV42 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.4742446043165425 0.1381373390013476 0.8901318763827113 1.0 0.906855979888368 2 O75880 1 +Copper chaperone SCO1/SenC [IPR003782] 0.4742446043165425 0.1381373390013476 0.8901318763827113 1.0 0.906855979888368 2 O75880 1 +Stromal interaction molecule [IPR037608] 0.4587050359712182 0.1138544901239343 0.9093531425118976 1.0 0.9241746990157996 2 Q9P246 1 +Mpv17/PMP22 [IPR007248] 0.4594760161369301 0.1023627079101287 0.9184687829199902 1.0 0.9321510909925188 3 Q9NR77 1 +Sorting nexin-5/6/32 [IPR014637] 0.4425899280575492 0.0921588614588374 0.9265718226961456 1.0 0.9396569972914728 2 Q9Y5X3 1 +Sas10/Utp3/C1D [IPR007146] 0.4256115107913626 0.0729685269088743 0.9418311626128596 1.0 0.9540394201534 2 Q9NQZ2 1 +Constitutive coactivator of PPAR-gamma [IPR026784] 0.4241726618704994 0.0715075419374493 0.9429938223278612 1.0 0.954651896970996 2 Q96EK7 1 +Dephospho-CoA kinase [IPR001977] 0.4155395683453191 0.0632606083475379 0.9495589828902444 1.0 0.9600373734929144 2 Q13057 1 +Kinesin light chain [IPR002151] 0.4197372673748651 0.0532837423771672 0.9575058335027202 1.0 0.967703689470037 3 Q9H0B6 1 +G-protein alpha subunit, group I [IPR001408] 0.3902158273381249 0.0438489077186043 0.965024841827362 1.0 0.9745613853041812 2 P08754 1 +Glycosyl transferase, family 8 [IPR002495] 0.3769784172661821 0.0362316221831893 0.9710976716798848 1.0 0.9799493025649276 2 P46976 1 +Structural maintenance of chromosomes protein [IPR024704] 0.3319896343219082 0.0342365803851056 0.9726884967001276 1.0 0.9811819801565068 4 Q9UQE7,O95347,Q9NTJ3 3 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.3903281519861646 0.0283582537913182 0.9773764194475232 1.0 0.984789209887019 3 P08754,Q14344 2 +Tetraspanin, animals [IPR000301] 0.3208633093525128 0.0181348636317309 0.98553126536369 1.0 0.9922533429599564 2 O60637 1 +Translation Initiation factor eIF- 4e [IPR001040] 0.3087769784172607 0.016345731188895 0.9869585741929884 1.0 0.9933139892540794 2 O60573 1 +Chaperone DnaJ [IPR012724] 0.3534830166954407 0.00838445785291 0.99331024890917 1.0 0.9970628376847998 3 Q96EY1,P31689 2 +Proteasome, subunit alpha/beta [IPR001353] 0.245235847343479 0.0032851499574543 0.9973788342837212 1.0 1.0 14 P49721 1 +Phosphatidylinositol kinase [IPR015433] 0.329324254909213 0.0005333277793306 0.999574466019198 1.0 1.0 3 P42356 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..dcaf0489fd8e1e55c51c1ad036a2f516631aa8d6 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3 [IPR022968]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome non-ATPase regulatory subunit 9 [IPR035269]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S10, mitochondrial [IPR040055]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S18b, mitochondrial [IPR040054]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abl interactor 1 [IPR028456]", "Acetoacetyl-CoA synthase [IPR005914]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating transcription factor 7-interacting protein [IPR026085]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat and SAM domain-containing protein 1A [IPR033637]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit [IPR006111]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-type fold containing protein ARMC8/Vid28 [IPR038739]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2 [IPR033093]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell lymphoma/leukemia 10/E10 [IPR033238]", "B-cell receptor-associated protein 29/31 [IPR008417]", "B9-type C2 domain [IPR010796]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Bet3 family [IPR016721]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-2-syntrophin [IPR028550]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-adducin [IPR027773]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "C2H2-type Zinc finger protein, YY1-like [IPR017114]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 2 [IPR037354]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-2 [IPR035702]", "Caspase-3/7 [IPR015471]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein Cenp-K [IPR020993]", "Centromere protein Cenp-M [IPR020987]", "Centromere protein I [IPR012485]", "Centromere protein U [IPR025214]", "Centrosomal protein of 131kDa [IPR030465]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 44kDa [IPR033603]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 167 [IPR028194]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit VIb [IPR003213]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 15 [IPR038914]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XPF [IPR006167]", "DNA repair protein XRCC4 [IPR010585]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA replication/checkpoint protein [IPR021110]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit RPB6 [IPR028363]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dim1 family [IPR004123]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF123/RSPRY1-like [IPR045129]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase RNF31-like [IPR026254]", "E3 ubiquitin-protein ligase Rad18 [IPR039577]", "E3 ubiquitin-protein ligase UBR1-like [IPR039164]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "ETS family [IPR046328]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM98 [IPR018797]", "FUN14 [IPR007014]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferritin [IPR001519]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Formin-binding protein 1-like [IPR030116]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Rheb [IPR037586]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Gasdermin-E [IPR042377]", "Gem-associated protein 4 [IPR033265]", "Gemin6 [IPR009422]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glucocorticoid receptor [IPR001409]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-rich protein 1 [IPR026719]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione Transferase family [IPR040079]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-binding protein, beta subunit [IPR016346]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS augmin-like complex subunit 7-like [IPR029711]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HIRA-interacting protein 3 [IPR037647]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group nucleosome-binding domain-containing protein 5 [IPR040164]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase GCN5 [IPR037800]", "Histone acetyltransferase GCN5/PCAF [IPR016376]", "Histone acetyltransferase Rtt109/CBP [IPR013178]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Hyccin [IPR018619]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "I-BAR domain containing protein MTSS1/MTSS2 [IPR030127]", "I-BAR domain containing protein MTSS2 [IPR030059]", "ICln [IPR003521]", "IQ calmodulin-binding motif-containing protein 1 [IPR028765]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor-interacting protein [IPR024797]", "Inositol 1,4,5-trisphosphate receptor-interacting protein family [IPR026250]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase [IPR033942]", "Inositol monophosphatase, lithium-sensitive [IPR020552]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 8 [IPR038751]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "Junctional protein associated with coronary artery disease [IPR028221]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Katanin p60 subunit A1 [IPR028596]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-associated protein 3 [IPR008658]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore scaffold 1 [IPR037388]", "Kinetochore-associated protein Dsn1/Mis13 [IPR013218]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LIM domain-binding protein 1 [IPR030167]", "LIM domain-containing protein 1 [IPR028734]", "LIM-domain binding protein/SEUSS [IPR029005]", "LMBR1-like membrane protein [IPR006876]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine carboxyl methyltransferase 1 [IPR016651]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat flightless-interacting protein 1/2 [IPR019139]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Liprin-beta-1 [IPR030437]", "LisH domain-containing protein ARMC9 [IPR040369]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "MAX gene-associated protein [IPR037935]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MICRORCHIDIA ATPase family [IPR045261]", "MOB kinase activator family [IPR005301]", "MORF4 family-associated protein 1 [IPR029254]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Menin [IPR007747]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial dynamics protein MID49/MID51 [IPR045909]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Motile sperm domain-containing protein 1 [IPR039283]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 14 [IPR039802]", "Myotubularin-related protein 4 [IPR030590]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyltransferase II [IPR007754]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "N6-adenosine-methyltransferase non-catalytic subunit METTL14-like [IPR045123]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain M/4 [IPR010227]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase [IPR003918]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5 [IPR019342]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "NURS complex subunit red1 [IPR039278]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural Wiskott-Aldrich syndrome protein [IPR030214]", "Neurochondrin [IPR008709]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuroplastin [IPR027112]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Notch [IPR008297]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OCIA domain-containing protein 1/2 [IPR040187]", "ORC ubiquitin ligase 1 [IPR039209]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "PSME3-interacting protein [IPR039845]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Patatin-like phospholipase domain-containing protein [IPR033562]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phorbol-12-myristate-13-acetate-induced protein 1 [IPR024140]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polycomb protein EED [IPR037352]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SLU7 [IPR039974]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable cytosolic iron-sulfur protein assembly protein, CIAO1/Cia1 [IPR028608]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein C10 [IPR026317]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM118 [IPR038916]", "Protein FAM118B [IPR033352]", "Protein FAM8A1 [IPR039871]", "Protein FRG1 [IPR010414]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein MMS22-like [IPR042320]", "Protein Mon2-like [IPR026829]", "Protein NDRG1 [IPR030693]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A11 [IPR028482]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein Unc-13 [IPR027080]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF3512 [IPR021900]", "Protein of unknown function DUF4559 [IPR027897]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF5565 [IPR041211]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, RluC/RluD [IPR006225]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RAD51-associated protein 1 [IPR026632]", "RFT1 [IPR007594]", "RFX-like DNA-binding protein [IPR039779]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cap guanine-N2 methyltransferase [IPR019012]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, Rpb8 [IPR005570]", "RNA polymerase, subunit omega/Rpo6/RPB6 [IPR006110]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit Pop5/Rpp14/Rnp2-like [IPR002759]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab protein geranylgeranyltransferase component A [IPR001738]", "Rab-like protein 6 [IPR040385]", "Rab11-family interacting protein class I [IPR037789]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab39 [IPR041818]", "Rab3GAP regulatory subunit [IPR026059]", "Rad21/Rec8-like protein [IPR039781]", "Raftlin family [IPR028169]", "Ral GTPase-activating protein subunit beta [IPR039930]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinoblastoma-like protein 1 [IPR028310]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose 5-phosphate isomerase, type A [IPR004788]", "Ribose-5-phosphate isomerase, type A, subgroup [IPR020672]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L33 [IPR001705]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S27 [IPR000592]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SPRY domain-containing protein 7 [IPR035766]", "SSNA1 family [IPR033362]", "ST7 [IPR007311]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Sedoheptulokinase [IPR042027]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Selenoprotein F/M [IPR039992]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 12 [IPR034477]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase ATM/Tel1 [IPR015519]", "Serine/threonine-protein kinase MARK3 [IPR033628]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase TOUSLED-like 2 [IPR027086]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small acidic protein [IPR026714]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-8/Mvp1 [IPR028662]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingolipid delta(4)-desaturase DES1 [IPR031196]", "Sphingolipid delta4-desaturase [IPR011388]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 1 [IPR009829]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "StAR-related lipid transfer protein 9 [IPR042990]", "Stathmin family [IPR000956]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule 1 [IPR030463]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "Syntrophin [IPR015482]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex subunit 7/Mft1 [IPR008501]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TIP41-like protein [IPR007303]", "TMEM14 family [IPR005349]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPMT family [IPR008854]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "TSC-22 / Dip / Bun [IPR000580]", "Tankyrase 1-binding protein-like [IPR040006]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thiopurine S-methyltransferase [IPR025835]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor RelA (p65) [IPR030495]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, GA-binding, alpha subunit [IPR016312]", "Transcription factor, T-box [IPR001699]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Transposase, L1 [IPR004244]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin polyglutamylase TTLL4 [IPR027748]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosyl-DNA phosphodiesterase I [IPR010347]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis hydroxylase UbiH/COQ6 [IPR010971]", "Ubiquinone biosynthesis monooxygenase COQ6 [IPR000689]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein C3orf38 (DUF4518) [IPR026698]", "Uncharacterised protein family UPF0390 [IPR019034]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterized protein C11orf98 [IPR037691]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar (H+)-ATPase G subunit [IPR005124]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 11 [IPR016528]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps52 [IPR007258]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "Yos1-like [IPR013880]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger HIT domain-containing protein 2 [IPR039646]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 106 [IPR042622]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APC", "APEX1", "APEX2", "API5", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFIP1", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC8", "ARMC9", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BEND3", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD7", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C11orf58", "C11orf98", "C12orf29", "C12orf57", "C12orf73", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C21orf59", "C2CD2", "C2CD5", "C2orf49", "C3orf38", "C3orf58", "C5orf15", "C8orf33", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASP2", "CASP3", "CASP7", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CENPB", "CENPF", "CENPI", "CENPK", "CENPM", "CENPU", "CEP131", "CEP170", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHM", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CIAO1", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COIL", "COLGALT1", "COMMD2", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF15", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSN1", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFHD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC8", "EMD", "EMG1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERGIC3", "ERH", "ERICH1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAM114A2", "FAM118B", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM136A", "FAM162A", "FAM192A", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLVCR1", "FMR1", "FN3KRP", "FNBP1L", "FNTB", "FRG1", "FRYL", "FSCN1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GALK1", "GALM", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLS", "GLUD1", "GM2A", "GMFB", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPS1", "GPT2", "GRPEL1", "GRSF1", "GSDME", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAUS7", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGN5", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HYOU1", "IARS", "IARS2", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS5", "INTS7", "INTS8", "IPO4", "IPO5", "IQCB1", "IRGQ", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JCAD", "JPT2", "JUP", "KARS", "KAT2A", "KATNA1", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF5B", "KIFAP3", "KIFBP", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNL1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "LAMP1", "LAMTOR1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT1", "LDAH", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMBRD2", "LMF2", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LRRFIP1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED17", "MED23", "MED24", "MED4", "MEN1", "MEPCE", "MESD", "METAP2", "METTL1", "METTL14", "METTL16", "METTL3", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC3", "MORF4L1", "MOSPD1", "MOV10", "MPC2", "MPDU1", "MPHOSPH10", "MPI", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTR", "MTSS1L", "MTX1", "MTX2", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "ND4", "NDC1", "NDC80", "NDRG1", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFAF3", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NF1", "NFS1", "NGDN", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRDE2", "NRM", "NSA2", "NSF", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARG", "PARK7", "PARN", "PATL1", "PAWR", "PBDC1", "PBRM1", "PC", "PCBD1", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA2", "PNPT1", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABAC1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RAC3", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBL1", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFT1", "RFTN1", "RFX1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX2", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG5", "SMIM4", "SMPD4", "SMS", "SMU1", "SMYD3", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPNS1", "SPPL2A", "SPR", "SPRYD7", "SPTBN1", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "ST7", "STAG1", "STAG2", "STARD3", "STARD9", "STAT1", "STAT3", "STIM1", "STIM2", "STIP1", "STMN1", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP1", "TECR", "TEDC1", "TEFM", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", 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sha256:95d79ecc5ab508f494ae570c85ef20fb2007b73d21e9ed870890fa0517d25163 +size 133103 diff --git a/interpro_homologous_superfamily/basic/plot_8.png b/interpro_homologous_superfamily/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..ba05c449c76f74e3920c134976d3d5c7e1e4ee1f --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bcb3576c8290e931b5b9ee041dbbe8a1203b7de4738189f06dee2f1f651695f9 +size 134538 diff --git a/interpro_homologous_superfamily/basic/plot_9.png b/interpro_homologous_superfamily/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..fb32ab810f30461f60f57d7bb6ee5290a9715f6e --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5de948b090b94bd02f4af0031a64e51ed3534f4dab889a095056d6d15d050b19 +size 136036 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7fb6cfea033b13149bc5e72b7c0ff35b5375acf5 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:21f27b7f663771c393926c5dc4cc9e1db6211bb1c4aae126d74c0e568f561833 +size 191733 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0f2c4b6c673daeec2214d420fb9ec830133c2351 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,18 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 57 131 5.789779956870737 7.047869392429947e-09 41.78155339805825 126.65533980582524 0.1165973051667422 0.543214063567699 13.579176287791377 6.87987395678373 1.6323826073741117 0.3875195330163939 7.737357832762677e-06 0.2459530387672467 0.0007074828077167 1.7536568067188944e-08 2.8345143604883364e-15 +RNA-binding domain superfamily [IPR035979] 56 133 5.6757970605547206 1.3804435758435613e-08 42.40291262135922 128.71601941747574 0.0615554024640467 0.5527296641044032 14.098054374547743 6.713949807605091 1.6556654950344032 0.3906506493803742 3.04243241231912e-05 0.2424540817316537 0.0006627325516806 7.47474383833615e-08 5.531430588194543e-14 +EF-hand domain pair [IPR011992] 16 52 3.633241840939527 0.0002798824633432 13.3252427184466 49.37378640776699 0.9065364020670126 0.4404331516970506 4.9772339658485505 4.730718887980642 1.169914018421813 0.3730081256676846 0.0030827872533409 0.0217241970341978 0.1231026090672371 0.0002523211654808 0.0001382833794345 +MFS transporter superfamily [IPR036259] 8 11 3.0923801267023903 0.0019855840946934 3.6432038834951457 8.356796116504855 0.9436301622284156 0.2543148229816532 1.924895010927015 2.2984539817025564 1.2198539986610124 0.2448337840515702 0.06443512813817 0.2031027035797352 0.0775813155228076 0.005869339632186 0.0004418539826712 +Alpha/Beta hydrolase fold [IPR029058] 10 27 3.0091348643529714 0.002619927889303 7.793689320388349 25.487864077669904 0.3803730368869525 0.1931612116461074 2.8504230618688027 2.5849355029363217 1.9090082785106757 0.2379814650369476 4.86965927429328e-06 0.0395283360833688 0.0004462949229121 3.1176850956108185e-05 0.0003552725958063 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 4 7 2.768401943420722 0.0056331934117459 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.001354096353283 0.0550816697898294 0.0056684159955205 0.000142755965642 0.000160552482799 +Zinc finger, RanBP2-type superfamily [IPR036443] 7 10 2.306652433874394 0.0210742039532541 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 0.0607884384663988 1.0 0.0170518298819148 0.0135296171343662 0.002864460747413 +Mitochondrial carrier domain superfamily [IPR023395] 5 20 2.293530096331017 0.021817504694535 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.036064976370089 0.1644315705571846 0.0513963234576887 0.0130060888805635 0.0095095891823194 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 3 5 2.248282194745712 0.0245582013424412 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 1.5474587290270297e-05 0.04159641685533 0.0031504918831051 3.848915456526504e-05 0.0005776438679051 +Peptidase M4/M1, CTD superfamily [IPR027268] 3 5 2.248282194745712 0.0245582013424412 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 1.5474587290270297e-05 0.04159641685533 0.0031504918831051 3.848915456526504e-05 0.0005776438679051 +Aldehyde dehydrogenase, C-terminal [IPR016163] 2 10 2.216200014154553 0.0266778069192621 3.2985436893203883 9.529126213592232 -0.5613485854973601 0.3657232034282902 1.9683657938952 0.6908740865654212 1.1218179525542225 0.2726859723953302 0.0021777683667008 0.0019049706229129 0.0002902447274798 0.0041946485896371 0.0280386150660574 +Aldehyde dehydrogenase, N-terminal [IPR016162] 2 10 2.216200014154553 0.0266778069192621 3.2985436893203883 9.529126213592232 -0.5613485854973601 0.3657232034282902 1.9683657938952 0.6908740865654212 1.1218179525542225 0.2726859723953302 0.0021777683667008 0.0019049706229129 0.0002902447274798 0.0041946485896371 0.0280386150660574 +Aldehyde/histidinol dehydrogenase [IPR016161] 2 10 2.216200014154553 0.0266778069192621 3.2985436893203883 9.529126213592232 -0.5613485854973601 0.3657232034282902 1.9683657938952 0.6908740865654212 1.1218179525542225 0.2726859723953302 0.0021777683667008 0.0019049706229129 0.0002902447274798 0.0041946485896371 0.0280386150660574 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 3 7 2.120571005690673 0.0339579202581512 1.9684466019417477 5.997572815533981 0.2946237832337159 0.497347338748234 1.2113839131393174 0.825852858399742 0.8897370326497382 0.2801827517665021 3.932001466113351e-05 0.0506073598520519 0.0047533286028597 9.701143498590324e-05 0.0013990642028563 +HAD superfamily [IPR023214] 8 21 2.09481386914003 0.0361875417354826 5.905339805825243 19.805825242718445 0.5764874318568467 0.4905542596212732 2.7813998415737995 2.7290535093395536 0.8549369097345116 0.3043048374614219 0.0926012272363195 0.0284424316807039 0.1009015630926116 0.0463117823544705 0.0183758279429038 +HAD-like superfamily [IPR036412] 8 21 2.09481386914003 0.0361875417354826 5.905339805825243 19.805825242718445 0.5764874318568468 0.4905542596212732 2.7813998415737995 2.7290535093395536 0.8549369097345116 0.3043048374614219 0.1082892137815036 0.0323055044295255 0.1132051672598368 0.0571243888921134 0.0259419504317075 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 3 7 1.9873333085967173 0.0468854728445067 2.6067961165048543 7.0 0.7914914082442276 0.4366893661235884 1.5075062759483802 0.0 0.8715475629418188 0.3304871916560691 1.0 1.0 1.0 1.0 0.0034775277607499 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..95b75b381b9563b6374c6af95357e0a5536eb2be --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 995, + "title": "Average number of proteins per term", + "value": 5.089447236180905 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3594a8286c3e09b401d8b55266b9fdba158b2b22 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..171908b39d7809e3f3934c5d99ddaff23e6c346c --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,137 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.570645869096883 5.789779956870737 7.047869392429947e-09 7.012605482742067e-06 6.867706790319215e-06 131 O60506,Q96DH6,Q07955,Q9UHX1,P18615,Q9H501,O43390,P33240,P19338,Q9P2K5,Q13148,P98175,O14979,Q86V81,P22626,Q13595,Q8IXT5,P98179,Q14011,Q99729,Q13151,P62995,P38159,Q53F19,Q96PK6,P31942,Q96I25,Q15056,P23246,P23588,Q01844,P35637,Q96E39,P52272,O75494,P78332,Q9Y2U8,Q01130,Q92804,Q01085,P43243,Q15233,P52597,O15047,P52756,Q16540,Q8WXF0,Q13242,P55795,Q8N684,Q96EP5,O95453,Q76FK4,P51991,Q15427,P31943,Q8WXF1 57 +RNA-binding domain superfamily [IPR035979] 0.5558984139302784 5.6757970605547206 1.3804435758435611e-08 1.3735319345080722e-05 6.867706790319215e-06 133 O60506,Q96DH6,Q07955,Q9UHX1,P18615,O43390,P33240,P19338,O60318,Q9P2K5,Q13148,P98175,O14979,Q86V81,P22626,Q13595,Q8IXT5,P98179,Q14011,Q99729,Q13151,Q71RC2,P62995,P38159,Q96PK6,P31942,Q96I25,Q15056,P23246,P23588,Q01844,P35637,Q96E39,P52272,O75494,P78332,Q9Y2U8,Q01130,Q92804,Q01085,P43243,Q15233,P52597,O15047,P52756,Q8WXF0,Q13242,P55795,Q8N684,Q96EP5,O95453,Q76FK4,P51991,Q15427,P31943,Q8WXF1 56 +EF-hand domain pair [IPR011992] 0.5625984228559238 3.633241840939527 0.0002798824633432 0.2430984066433981 0.0518754402107889 52 Q96AY3,Q9UJS0,Q14257,O43852,Q02818,Q9BRK5,O95302,Q96D71,Q8N163,P0DP25,Q9Y680,Q9UBV8,P22681,Q9NWM8,P41208,Q8IYU8 16 +MFS transporter superfamily [IPR036259] 0.8394615409699422 3.0923801267023903 0.0019855840946934 0.8616017928777151 0.0518754402107889 11 O00400,P41440,Q99808,Q16625,Q9H2V7,P53985,Q9Y5Y0,Q14728 8 +Alpha/Beta hydrolase fold [IPR029058] 0.6220709450183105 3.0091348643529714 0.002619927889303 0.9264837697241188 0.0518754402107889 27 Q9H3G5,Q4J6C6,Q9HB40,Q9UMR5,P07099,Q9NUJ1,Q8NCC3,P34913,P42785,P50897 10 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.9020241513254688 2.768401943420722 0.0056331934117459 0.9963785257548572 0.0544177421814293 7 O43169,Q8WUJ1,Q9UMX5,O15173 4 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.7184721123073857 2.306652433874394 0.0210742039532541 0.9999999993747928 0.1145837865217914 10 P52756,Q01844,P49790,P35637,Q96EP0,Q92804,P98175 7 +Mitochondrial carrier domain superfamily [IPR023395] 0.5845333223337227 2.293530096331017 0.021817504694535 0.9999999997063788 0.1173427955192559 20 O43772,Q9UJS0,Q9Y619,Q70HW3,Q9BQT8 5 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.8745600833761595 2.2482821947457117 0.0245582013424412 0.9999999999819966 0.1227910067122062 5 P55786,Q9UIQ6,P09960 3 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.8745600833761595 2.2482821947457117 0.0245582013424412 0.9999999999819966 0.1227910067122062 5 P55786,Q9UIQ6,P09960 3 +Aldehyde dehydrogenase, C-terminal [IPR016163] 0.7011467058862818 2.216200014154553 0.0266778069192621 0.999999999997933 0.1270057052814801 10 P30837,O94788 2 +Aldehyde dehydrogenase, N-terminal [IPR016162] 0.7011467058862818 2.216200014154553 0.0266778069192621 0.999999999997933 0.1270057052814801 10 P30837,O94788 2 +Aldehyde/histidinol dehydrogenase [IPR016161] 0.7011467058862818 2.216200014154553 0.0266778069192621 0.999999999997933 0.1270057052814801 10 P30837,O94788 2 +NAP-like superfamily [IPR037231] 0.923417513459042 2.191758926949725 0.0283969183061993 0.999999999999644 0.1291899992047319 4 P55209,Q01105 2 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.7592877250003573 2.1205710056906732 0.0339579202581512 0.9999999999999988 0.148193555512546 7 Q9NTG7,P49366,Q8IXJ6 3 +HAD superfamily [IPR023214] 0.545079090415963 2.09481386914003 0.0361875417354826 1.0 0.1525703560457849 21 Q5TFE4,P49902,Q9H857,Q9HD20,P98194,Q969T7,P34913,Q9BSH5 8 +HAD-like superfamily [IPR036412] 0.5450790904159629 2.09481386914003 0.0361875417354826 1.0 0.1525703560457849 21 Q5TFE4,P49902,Q9H857,Q9HD20,P98194,Q969T7,P34913,Q9BSH5 8 +Regulatory factor, effector binding domain superfamily [IPR011256] 0.9884892086330934 2.0060852733409225 0.0448471507945549 1.0 0.1736300196131601 2 Q9NRV9 1 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.7311971155203967 1.9873333085967175 0.0468854728445067 1.0 0.180119866719244 7 P22695,Q5JRX3,Q10713 3 +Oxysterol-binding protein superfamily [IPR037239] 0.756567136302336 1.9494078831183297 0.0512467338612703 1.0 0.186778388981553 6 Q9BZF3 1 +WGR domain superfamily [IPR036930] 0.9720863309352517 1.938906688421372 0.0525127013904787 1.0 0.1869721621142085 2 Q9UGN5 1 +Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616] 0.9720863309352517 1.938906688421372 0.0525127013904787 1.0 0.1869721621142085 2 Q9UGN5 1 +WW domain superfamily [IPR036020] 0.6160271542733455 1.903574389102883 0.0569656369361051 1.0 0.1975111427150217 11 Q6ZWJ1,O75400,Q8WYQ5,Q96PU5,P46934 5 +Isoprenoid synthase domain superfamily [IPR008949] 0.775875880370084 1.8215964649412968 0.068516237719872 1.0 0.2199150210686215 5 P37268 1 +Haem oxygenase-like, multi-helical [IPR016084] 0.9381294964028772 1.7989635823104515 0.0720244416222084 1.0 0.2275057759177695 2 P30519 1 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.9372661870503594 1.7953917977610572 0.0725912983751806 1.0 0.2285707021623567 2 A6NIH7 1 +Porin domain superfamily [IPR023614] 0.8156951058016121 1.7496583321457952 0.0801772877283402 1.0 0.2488127047334981 4 P21796,P45880 2 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4966252115464303 1.7396768598852883 0.0819157747759409 1.0 0.2488127047334981 21 Q6NUM9,Q16134,Q9UHG3,O95831,Q9Y2Z9 5 +TFIIS/LEDGF domain superfamily [IPR035441] 0.7028840077352106 1.7000181829321166 0.089127505393967 1.0 0.2584992800072073 6 Q7Z4V5,Q14241,Q96ST2 3 +BSD domain superfamily [IPR035925] 0.9105035971223016 1.6843746761566858 0.0921092817006308 1.0 0.2593930096060411 2 Q9NW68 1 +K Homology domain, type 1 superfamily [IPR036612] 0.4527110991647801 1.6667077815920088 0.0955725248356222 1.0 0.2648876384719894 27 P51114,P61978,Q96I24,Q96AE4,O75525,Q07666,Q92945 7 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.793752951034498 1.6576047499918038 0.0973972703052381 1.0 0.2665471898338191 4 Q9BYT8,P42892 2 +Death-like domain superfamily [IPR011029] 0.6602783387672817 1.6430845668428635 0.1003654375292752 1.0 0.2691741518642289 7 Q7Z434,P42575,Q13546 3 +Cytochrome P450 superfamily [IPR036396] 0.8989928057553951 1.636474007911563 0.1017404212279591 1.0 0.2711310718392724 2 Q6UW02 1 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.8791366906474811 1.5536853979894736 0.1202594778052463 1.0 0.296918561826849 2 Q15392 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.8791366906474811 1.5536853979894736 0.1202594778052463 1.0 0.296918561826849 2 Q15392 1 +Sirtuin, catalytic core small domain superfamily [IPR026591] 0.8831773934259888 1.463353823003924 0.1433705871646775 1.0 0.3249515586078682 3 Q8IXJ6 1 +SWAP/Surp superfamily [IPR035967] 0.650235157363308 1.4505070822712445 0.1469171656615611 1.0 0.3307298186272698 6 Q8IWZ8,Q8IWX8 2 +Prefoldin [IPR009053] 0.6852572806185745 1.4159057086634137 0.1568031133219258 1.0 0.3467091061229249 5 Q99471,Q9UHV9,O15212 3 +Bcl-2-like superfamily [IPR036834] 0.73566272137946 1.411514390651773 0.158092995410402 1.0 0.3487860985218403 4 Q9BXK5 1 +Zinc finger, FYVE/PHD-type [IPR011011] 0.4080467813752862 1.384322090552584 0.1662598528442427 1.0 0.3611977152402216 30 O96028,P29375,Q9UPP1,Q92576,Q96L73,Q9UPN9,Q03164,Q96T51,O94880,O15164,O14964,Q9P1Y6,Q9ULU4 13 +Six-bladed beta-propeller, TolB-like [IPR011042] 0.7213498261047949 1.3505135685174348 0.1768513043206141 1.0 0.3696786718466619 4 Q15165 1 +LEM/LEM-like domain superfamily [IPR011015] 0.6242582809340999 1.3260757392423184 0.1848146112073643 1.0 0.378375592903966 6 Q9Y2U8,P42166,Q86XL3 3 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.319456920400704 1.3073111124299637 0.1911070716854743 1.0 0.3872740047394032 94 Q96TC7,Q5R3I4,O75718,Q32P28,Q9H7B4,Q07866,Q13217,Q9H270,Q9UJX3,Q9UJX4,Q9NYH9,Q6P3X3,O15091,Q9UPR3,P49792,P33981,Q75QN2,Q6P2P2,Q9H0B6,Q15020,Q96EK5,A0AVF1,O15460,Q92791,Q9Y3D6,Q9Y6X3,P13674,Q86UA1,O00231,Q15006,O43765,Q9UNE7,Q9Y5A7,Q9UGR2,Q6DKK2,Q9UJX2,O75153,Q14318,P49321 39 +Lamin tail domain superfamily [IPR036415] 0.8425446171560111 1.3059717475365358 0.1915621655108963 1.0 0.3874072249661419 3 Q03252,P20700 2 +Tubulin/FtsZ, C-terminal [IPR008280] 0.6570109046895831 1.287713168972308 0.1978458277201431 1.0 0.3945022015662172 5 P07437,P68371 2 +Tubulin, C-terminal [IPR023123] 0.6570109046895831 1.287713168972308 0.1978458277201431 1.0 0.3945022015662172 5 P07437,P68371 2 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.6570109046895831 1.287713168972308 0.1978458277201431 1.0 0.3945022015662172 5 P07437,P68371 2 +Acyl-CoA binding protein superfamily [IPR035984] 0.8327947295313286 1.2682268409356712 0.2047169543938292 1.0 0.4033532071720001 3 O75521 1 +C2 domain superfamily [IPR035892] 0.403240096404728 1.217136965073121 0.2235521084702729 1.0 0.425574441339242 26 Q96PE3,O14976,Q86YQ8,O14795,Q6WKZ4,Q96PU5,Q9UGP8,P46934,P05771 9 +HIV integrase-binding domain superfamily [IPR036218] 0.7976978417266172 1.2139152816124863 0.2247800767670003 1.0 0.4257232559810586 2 Q7Z4V5 1 +VPS9 domain superfamily [IPR037191] 0.7948201438848905 1.2019687745058525 0.2293756263319393 1.0 0.4330716284635286 2 Q14C86 1 +Chaperone J-domain superfamily [IPR036869] 0.4305964432607115 1.1837546198124649 0.2365102107318391 1.0 0.4423452249589847 20 O14976,Q8WXX5,Q13217,Q96KC8,Q9Y2G8,O75190,O75937,Q96EY1,Q9UGP8 9 +ESCRT assembly domain [IPR037202] 0.7775539568345307 1.130492214298252 0.2582688772752368 1.0 0.4605910412550376 2 Q9H9H4 1 +AH/BAR domain superfamily [IPR027267] 0.4422194139086957 1.1304152111125727 0.2583013075581015 1.0 0.4605910412550376 17 Q9Y5X2,Q9UQB8,P53367,Q9UKG1,Q13596,Q9Y5X1 6 +Bromodomain-like superfamily [IPR036427] 0.4342461684071666 1.1150597084501408 0.2648248359541956 1.0 0.469452282569524 18 Q6PL18,O60885,Q86U86,Q9UPN9,Q9NPI1,Q03164,O15164,Q92830,Q9ULU4 9 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.7880924369843243 1.0958337871362347 0.2731515195347074 1.0 0.4817489158939252 3 Q9BYT8 1 +Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784] 0.7689208633093507 1.0949103435532623 0.2735559170653947 1.0 0.4817489158939252 2 Q15118 1 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.5141745998311094 1.0649829369091075 0.2868836513638517 1.0 0.5007969397993255 8 P08183 1 +Ribokinase-like [IPR029056] 0.775762809441556 1.048618150940457 0.2943538985217899 1.0 0.5038372216256879 3 P55263,Q9BRR6 2 +Proteasome activator superfamily [IPR036252] 0.7748992515831848 1.0453188512054623 0.295875627865525 1.0 0.5038372216256879 3 P61289,Q9UL46 2 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.7748992515831848 1.0453188512054623 0.295875627865525 1.0 0.5038372216256879 3 P61289,Q9UL46 2 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.7748992515831848 1.0453188512054623 0.295875627865525 1.0 0.5038372216256879 3 P61289,Q9UL46 2 +GOLD domain superfamily [IPR036598] 0.5951229153508295 1.0068194948312734 0.3140215245373463 1.0 0.5149750696378416 5 Q15363,Q9Y3B3,Q9H3P7 3 +DCN1-like, PONY binding domain [IPR042460] 0.7467625899280557 1.004208013833136 0.3152783602059683 1.0 0.5149750696378416 2 Q92564 1 +UBA-like superfamily [IPR009060] 0.3829520711078912 0.9882026826050722 0.3230533946411622 1.0 0.5235148659087239 23 Q9NRR5,Q14157,Q9UNZ2,Q9BSL1,Q9H1I8,Q96RU2,P22681,Q13501 8 +Heavy metal-associated domain superfamily [IPR036163] 0.7395683453237389 0.97499228676129 0.3295640860302624 1.0 0.5306088440131248 2 Q9NVT9 1 +Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930] 0.752516137459347 0.960224235035412 0.3369423721251716 1.0 0.5338497774913149 3 P48449 1 +Zinc finger, RING/FYVE/PHD-type [IPR013083] 0.2950958390927166 0.9450533471091176 0.3446316413574963 1.0 0.5417195626393505 69 O75150,Q03164,P38398,Q9H270,P29083,Q96L73,Q5VTR2,Q96DX4,P22681,O95155,Q9NS91,O14964,Q99590,Q6UWE0,Q92576,Q9UPN9,Q5W0B1,O15164,Q9ULU4,Q96T23,P29375,O96028,Q96T51,Q96EP0,Q9UNE7,Q5XPI4,O94880,Q7Z5J4,Q9P1Y6 29 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.5435414896340651 0.9384516339300004 0.3480123615219619 1.0 0.5424829719459523 6 P07437,P68371 2 +High mobility group box domain superfamily [IPR036910] 0.4484869651568259 0.921476637496145 0.3568016331182757 1.0 0.5495628869236601 11 Q969G3,O96028 2 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.7251409337063828 0.8575583207308141 0.3911363980093338 1.0 0.5826058623043222 3 P35611 1 +Enoyl-CoA hydratase, C-terminal [IPR014748] 0.7221583939414826 0.8464892642317643 0.3972798603933907 1.0 0.5864888146757029 3 Q13011 1 +DUSP-like superfamily [IPR035927] 0.6011420675522803 0.8415936275516426 0.4000154574490251 1.0 0.5896524150544888 4 P51784,Q9Y4E8 2 +Protein kinase-like domain superfamily [IPR011009] 0.2877888259163868 0.8045128191601997 0.4211008689422963 1.0 0.6054846309213655 84 P51812,Q9HBU6,Q15418,P49761,P31749,P35790,P05771 7 +ENTH/VHS [IPR008942] 0.4099256503769015 0.800943362423031 0.423164435190432 1.0 0.606481974868967 12 O15042,Q8IWX8,Q5VT52,Q14677,O14964,Q9NQG5,Q9UJY4,Q9UPN6 8 +Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236] 0.68892086330935 0.7739053208451296 0.4389867828269631 1.0 0.6165579968959891 2 P42356 1 +BAG domain superfamily [IPR036533] 0.7011049925453509 0.769144958321151 0.4418072613808868 1.0 0.6191524296816653 3 Q9UL15 1 +GYF-like domain superfamily [IPR035445] 0.6997452729678753 0.7642018674798453 0.4447469538648425 1.0 0.6217779783393094 3 O95400 1 +Zinc finger, NHR/GATA-type [IPR013088] 0.686330935251796 0.7638937312495421 0.4449305734448123 1.0 0.6217779783393094 2 P04150 1 +PH-like domain superfamily [IPR011993] 0.2868172351526306 0.757519911194616 0.4487384415676709 1.0 0.6234934476607703 65 P05067,P31749,Q9H4L5,Q9BZF3 4 +DNA-binding domain superfamily [IPR016177] 0.5390254118559005 0.7570968889691202 0.4489918177720147 1.0 0.6234934476607703 5 O95983,Q9UIS9,P51608 3 +Glycoside hydrolase superfamily [IPR017853] 0.3902691934423259 0.7273188761662743 0.4670306373440316 1.0 0.6313797339093905 15 P06865,O60502,P16278,Q9BTY2 4 +LAP1C-like, C-terminal domain superfamily [IPR038599] 0.6756834532374074 0.7230784776436112 0.4696316711604456 1.0 0.632985103417728 2 Q8NFQ8 1 +Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882] 0.6543884892086305 0.6432990465733496 0.5200300748255071 1.0 0.6746152861165313 2 Q7Z5L9 1 +Transcription elongation factor S-II, central domain superfamily [IPR036575] 0.655440414507762 0.6074644891771162 0.5435427021307855 1.0 0.6897964959630846 3 P23193,Q92576 2 +Histidine phosphatase superfamily [IPR029033] 0.503730891520157 0.606142764170377 0.5444199558608158 1.0 0.6897964959630846 5 Q9NPH0 1 +H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664] 0.626187050359709 0.5421845509202626 0.5876913769180903 1.0 0.721917185226543 2 Q96HR8 1 +Acyl-CoA N-acyltransferase [IPR016181] 0.3572972675179086 0.4913284202948665 0.6231941819203646 1.0 0.7475269135501384 12 O60502,Q92830,Q86UY6 3 +Zinc finger, CCCH-type superfamily [IPR036855] 0.400626105173583 0.4810565193828061 0.6304763296162508 1.0 0.7508827865758608 8 Q86VM9,Q9UGR2 2 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.7508827865758608 3 P10321 1 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.7508827865758608 3 P10321 1 +RuvA domain 2-like [IPR010994] 0.4699197428726706 0.469196653274777 0.6389290774616723 1.0 0.7559798427876201 5 Q14807,Q7KZ85,Q96QE5 3 +Translin, N-terminal [IPR016068] 0.6043165467625866 0.4680711689884868 0.6397336961077147 1.0 0.7559798427876201 2 Q15631 1 +Translin, C-terminal [IPR016069] 0.6043165467625866 0.4680711689884868 0.6397336961077147 1.0 0.7559798427876201 2 Q15631 1 +Translin superfamily [IPR036081] 0.6043165467625866 0.4680711689884868 0.6397336961077147 1.0 0.7559798427876201 2 Q15631 1 +NET domain superfamily [IPR038336] 0.598848920863306 0.4502122951230143 0.6525573716569664 1.0 0.7702189618015203 2 O60885 1 +Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151] 0.5694964028776943 0.359497061783475 0.7192232754648502 1.0 0.8292319340527531 2 Q9C0B1 1 +P-type ATPase, A domain superfamily [IPR008250] 0.373260179209296 0.3561474597197257 0.7217301365489059 1.0 0.8292395910694704 8 P98194,P35670,Q9HD20 3 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.373260179209296 0.3561474597197257 0.7217301365489059 1.0 0.8292395910694704 8 P98194,P35670,Q9HD20 3 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.373260179209296 0.3561474597197257 0.7217301365489059 1.0 0.8292395910694704 8 P98194,P35670,Q9HD20 3 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.5736902705814484 0.3502019331177288 0.7261871560987738 1.0 0.8324380418413364 3 P11717,P20645 2 +RmlC-like jelly roll fold [IPR014710] 0.3648754115784479 0.3486177659738995 0.727376288232892 1.0 0.832841664892667 9 Q8IY17 1 +BRCT domain superfamily [IPR036420] 0.3262902748153186 0.3359320568597842 0.7369221025153943 1.0 0.8408686834894694 14 P09874,P38398 2 +EB1, C-terminal domain superfamily [IPR036133] 0.5576978417266151 0.3257046342735244 0.744647837630104 1.0 0.8448399070033678 2 Q15691 1 +SAP domain superfamily [IPR036361] 0.321863531495321 0.3075664061848845 0.7584122857861517 1.0 0.85654963037142 13 Q9BUJ2,Q1KMD3,P12956,Q9NS91,Q14151,Q15424,P82979 7 +R3H domain superfamily [IPR036867] 0.5514037030739467 0.2900929174311412 0.7717451540175029 1.0 0.8702293796599586 3 O95453 1 +SH3-like domain superfamily [IPR036028] 0.2723075558291085 0.2762574734187456 0.7823503166315757 1.0 0.8794267996683651 35 P46108,Q00013,Q9UQB8 3 +GINS, helical bundle-like domain superfamily [IPR036224] 0.4456597628145692 0.2707985375807156 0.786545984709464 1.0 0.8820168459372699 4 Q9BRT9 1 +Immunoglobulin E-set [IPR014756] 0.3105645537316323 0.2686908012956615 0.7881676310669734 1.0 0.8820168459372699 16 A6NIH7 1 +Dbl homology (DH) domain superfamily [IPR035899] 0.3863439930855629 0.2581100116664435 0.7963220051208073 1.0 0.8862867954085047 6 Q92974,Q9NZM3,Q14155,Q9H8V3,Q12802 5 +Peptidase M41-like [IPR037219] 0.5093525179856073 0.2054729829850617 0.8372026042199026 1.0 0.9133953850864068 2 Q9Y4W6 1 +GAR domain superfamily [IPR036534] 0.4975539568345282 0.1809109192580323 0.8564374979473925 1.0 0.9242465406265246 2 Q03001 1 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.3549216015966262 0.1561535395726108 0.8759119974475842 1.0 0.9392850262532008 6 Q96DT7,Q96CX2 2 +Methylthiotransferase, N-terminal domain superfamily [IPR038135] 0.4785611510791323 0.1454808684486651 0.8843312198130833 1.0 0.9441089739420792 2 Q5VV42 1 +Radical SAM, alpha/beta horseshoe [IPR023404] 0.4785611510791323 0.1454808684486651 0.8843312198130833 1.0 0.9441089739420792 2 Q5VV42 1 +Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438] 0.4748201438848876 0.1391013553660502 0.889370057212592 1.0 0.9441856806680256 2 Q4G0N4 1 +NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064] 0.4748201438848876 0.1391013553660502 0.889370057212592 1.0 0.9441856806680256 2 Q4G0N4 1 +p53-like tetramerisation domain superfamily [IPR036674] 0.4722302158273337 0.1347998535779591 0.8927701216091162 1.0 0.9441856806680256 2 Q13043 1 +SH2 domain superfamily [IPR036860] 0.2827098723190367 0.1317506285765807 0.89518153870747 1.0 0.9441856806680256 12 P46108 1 +FERM/acyl-CoA-binding protein superfamily [IPR014352] 0.2812720412654502 0.1248123173021743 0.900672135851802 1.0 0.9473242866517368 13 O75521 1 +SMAD/FHA domain superfamily [IPR008984] 0.3070934256055259 0.1228215302931547 0.902248424633734 1.0 0.9479801293670173 9 Q14676,Q9P2P6,Q9BWU0,P46013,Q15058,O60934,Q5SW79,P55196 8 +K homology domain-like, alpha/beta [IPR015946] 0.4480575539568297 0.0991301777228627 0.9210349117303172 1.0 0.9596122902321104 2 O75616 1 +K homology domain superfamily, prokaryotic type [IPR009019] 0.4480575539568297 0.0991301777228627 0.9210349117303172 1.0 0.9596122902321104 2 O75616 1 +ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366] 0.4302158273381246 0.0778140015461016 0.9379760085981064 1.0 0.9711614240948137 2 P25705 1 +Tex-like domain superfamily [IPR023323] 0.4264748201438808 0.0738572091445254 0.9411240049657208 1.0 0.9713883661212576 2 Q7KZ85 1 +Tex-like protein, HTH domain superfamily [IPR023319] 0.4264748201438808 0.0738572091445254 0.9411240049657208 1.0 0.9713883661212576 2 Q7KZ85 1 +YqgF/RNase H-like domain superfamily [IPR037027] 0.4264748201438808 0.0738572091445254 0.9411240049657208 1.0 0.9713883661212576 2 Q7KZ85 1 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.4360202905801256 0.0711282335630838 0.9432956979386616 1.0 0.9726209527968582 3 P06865 1 +SMCs flexible hinge superfamily [IPR036277] 0.3320852534562272 0.0584450084189513 0.9533941644855116 1.0 0.9799867703131036 5 A6NHR9,Q9UQE7,O95347,Q9NTJ3 4 +CAP Gly-rich domain superfamily [IPR036859] 0.4107656879677418 0.0447235383818059 0.9643276715517302 1.0 0.9881627530318964 3 Q14203,Q99426 2 +L27 domain superfamily [IPR036892] 0.3340984981970415 0.036790050214603 0.9706524074577758 1.0 0.9936205199799248 4 Q9NZW5,O14936 2 +G protein alpha subunit, helical insertion [IPR011025] 0.3903281519861646 0.0283582537913182 0.9773764194475232 1.0 0.9994753724052268 3 P08754,Q14344 2 +Translation Initiation factor eIF- 4e-like [IPR023398] 0.3087769784172607 0.016345731188895 0.9869585741929884 1.0 1.0 2 O60573 1 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.3534830166954407 0.00838445785291 0.99331024890917 1.0 1.0 3 Q96EY1,P31689 2 +Zinc finger, CCHC-type superfamily [IPR036875] 0.2949308755760389 0.0031251753606342 0.9975064748888764 1.0 1.0 5 Q16629,Q5TAX3,Q7Z6E9,Q9NUD5 4 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fe84282d33c3ebb1bf2914c262a9ec9b34d8dc97 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CBP/p300, atypical RING domain superfamily [IPR038547]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coactivator CBP, KIX domain superfamily [IPR036529]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit VIb superfamily [IPR036549]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like [IPR012347]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Focal adhesion kinase, targeting (FAT) domain superfamily [IPR036137]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L1 transposable element, C-terminal domain [IPR042566]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MAP kinase activated protein kinase, C-terminal [IPR027442]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nuclear receptor coactivator, CREB-bp-like, interlocking domain superfamily [IPR037073]", "Nuclear receptor coactivator, interlocking [IPR009110]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PUB-like domain superfamily [IPR036339]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily [IPR038085]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPB6/omega subunit-like superfamily [IPR036161]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L33 superfamily [IPR038584]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S27, zinc-binding domain superfamily [IPR023407]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCAN domain superfamily [IPR038269]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKA1 microtubule binding domain [IPR042031]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Selenoprotein F/M, thioredoxin-like domain superfamily [IPR038219]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "T-box superfamily [IPR036960]", "TAP42/TAP46-like superfamily [IPR038511]", "TAZ domain superfamily [IPR035898]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "Wiscott-Aldrich syndrome protein, C-terminal [IPR011026]", "XPC-binding domain superfamily [IPR036353]", "XRCC4, N-terminal domain superfamily [IPR009089]", "XRCC4-like, N-terminal domain superfamily [IPR038051]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "AMFR", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APC", "APEH", "APEX1", "APEX2", "API5", "APMAP", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC8", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD5", "ATF7IP", "ATG4B", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATXN10", "ATXN2", "AURKA", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCAT2", "BCL10", "BCL2L12", "BCL2L13", "BCOR", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BMS1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD2", "C2CD5", "C3orf38", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CENPB", "CENPE", "CENPM", "CENPV", "CEP170", "CERS2", "CERS5", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHERP", "CHID1", "CHKA", "CHM", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FBL", "FBXL18", "FBXO22", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLVCR1", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSD1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLPH3", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD1L", "GPD2", "GPI", "GPKOW", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS14", "INTS4", "INTS7", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT2A", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT1", "LCOR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRSAM1", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MEPCE", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MLLT1", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD1", "MOSPD2", "MOV10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL33", "MRPL38", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA20", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDC80", "NDRG1", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF1", "NDUFAF3", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEK9", "NELFE", "NENF", "NF1", "NFATC2IP", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBDC1", "PBK", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RELA", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RPUSD3", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSU1", "RTCB", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SAAL1", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SELENOF", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPK", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMS", "SMU1", "SMYD3", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STARD3", "STARD7", "STARD9", "STAT1", "STAT3", "STIM1", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TAOK2", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "TGS1", "THADA", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "TIAL1", "TIGAR", "TIMM13", "TIMM44", "TIMM50", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM4", "TPMT", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TUT1", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBL5", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS11", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "VTA1", "WAPL", "WARS", "WARS2", "WASL", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR54", "WDR6", "WDR61", "WDR62", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP73", "WRN", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBED1", "ZBTB10", "ZC3H13", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZFC3H1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF106", "ZNF148", "ZNF24", "ZNF280C", "ZNF281", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZRANB2"], "leading_proteins": ["ABCB1", "ABHD10", "ACBD3", "ACP6", "ADD1", "ADK", "ADPGK", "AFDN", "AFG3L2", "AIFM1", "AKAP13", "AKT1", "ALDH1A2", "ALDH1B1", "ALYREF", "ANAPC5", "ANAPC7", "ANKLE2", "APP", "APPL1", "ARFIP1", "ARHGEF2", "ARHGEF7", "ARMC1", "ASCC2", "ATAD2", "ATP13A1", "ATP2C1", "ATP5A1", "ATP7B", "BAG5", "BAIAP2", "BCL2L13", "BRCA1", "BRD4", "BRD7", "BSDC1", "CALM3", "CALU", "CASK", "CASP2", "CBL", "CCAR2", "CD2BP2", "CDC23", "CDKAL1", "CEP170", "CETN2", "CHERP", "CHKA", "CIRBP", "CLINT1", "CLK3", "CLUH", "COQ6", "CPNE8", "CPSF7", "CPVL", "CRK", "CRTAP", "CSTF2", "CYB5B", "CYB5D2", "CYP20A1", "DAZAP1", "DCTN1", "DCUN1D4", "DGCR8", "DHCR24", "DHPS", "DNAJA1", "DNAJA3", "DNAJB6", "DNAJC1", "DNAJC16", "DNAJC3", "DNAJC8", "DNAJC9", "DST", "ECE1", "ECH1", "ECI2", "ECT2", "EIF4B", "EIF4E2", "EIF4H", "ELOA", "EMC2", "EPHX1", "EPHX2", "ERAL1", "ESF1", "ETFDH", "ETNK1", "EWSR1", "FDFT1", "FIS1", "FKBP10", "FKBP14", "FKBP7", "FKBP8", "FKBP9", "FLVCR1", "FTO", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "GAK", "GAPVD1", "GGA2", "GINS4", "GLB1", "GNA13", "GNAI3", "GTF2E1", "HDGFL2", "HDHD3", "HEBP1", "HEXA", "HGS", "HLA-C", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPUL1", "HNRNPUL2", "IGF2R", "INPP4A", "INTS8", "IRF2BP2", "ITSN2", "IWS1", "KAT2A", "KCTD12", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF14", "KIF22", "KIFBP", "KLC1", "KLC2", "KMT2A", "LARP4", "LEMD3", "LMNB1", "LMNB2", "LNPEP", "LRSAM1", "LSS", "LTA4H", "M6PR", "MAPRE1", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCM3AP", "MDC1", "MECP2", "MFSD10", "MGEA5", "MICU2", "MKI67", "MPP1", "MPP6", "MRPL23", "MSI2", "MYEF2", "NAA40", "NADK2", "NAF1", "NAP1L1", "NASP", "NBN", "NCBP3", "NCL", "NEDD4", "NEDD4L", "NELFE", "NENF", "NLN", "NOL8", "NONO", "NPEPPS", "NR3C1", "NSD1", "NSD2", "NSFL1C", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NUB1", "NUCB1", "NUP153", "OCLN", "OSBPL3", "OSBPL6", "P3H1", "P3H4", "P4HA1", "P4HA2", "PARN", "PARP1", "PARP2", "PBRM1", "PCYOX1", "PDK1", "PEF1", "PFDN2", "PFDN5", "PFDN6", "PGRMC2", "PHF14", "PHF3", "PHF8", "PHRF1", "PI4KA", "PITRM1", "PLA2G15", "PMPCA", "PNPLA6", "PON2", "PPT1", "PPT2", "PRCP", "PREPL", "PRKCB", "PRMT9", "PRPF39", "PRPF40A", "PSMD11", "PSME2", "PSME3", "PSPC1", "PUF60", "RAB11FIP1", "RAD18", "RAI1", "RANBP2", "RBBP6", "RBM10", "RBM12B", "RBM14", "RBM17", "RBM3", "RBM5", "RBM6", "RBMX", "RBMXL1", "RCN2", "REPS1", "RETSAT", "RIPK1", "RMDN3", "RNF123", "RNF20", "RNF219", "RNF31", "RNF40", "RPRD1B", "RPRD2", "RPS6KA1", "RPS6KA3", "RSF1", "RSPRY1", "RUFY1", "SAFB", "SAFB2", "SARNP", "SART3", "SCAF11", "SCAF8", "SCPEP1", "SDF4", "SEC63", "SET", "SETD1A", "SF3B4", "SFPQ", "SGTA", "SIRT2", "SIRT3", "SLC16A1", "SLC19A1", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A26", "SLC29A1", "SLC33A1", "SLC4A1AP", "SMARCE1", "SMC2", "SMC3", "SMC4", "SMCHD1", "SMG5", "SMYD3", "SNX1", "SNX8", "SNX9", "SPNS1", "SQSTM1", "SRSF1", "SRSF10", "SRSF12", "SRSF2", "SRSF7", "SRSF9", "STARD9", "STK4", "STUB1", "STXBP4", "SUGP1", "SUPT6H", "SYNCRIP", "TAF15", "TARDBP", "TBCB", "TCEA1", "TEFM", "TIAL1", "TMED2", "TMED7", "TMPO", "TOR1AIP2", "TRA2A", "TRA2B", "TRIM24", "TRIM33", "TSN", "TTC19", "TTC26", "TTC27", "TTC38", "TTK", "TUBB", "TUBB4B", "U2SURP", "UBAC1", "UBAP2L", "UBE4B", "UBQLN4", "UNC119B", "UNC13B", "UQCRC2", "USP11", "USP15", "USP28", "UTP6", "VDAC1", "VDAC2", "VPS11", "VPS37B", "XRCC6", "ZBTB10", "ZC3H18", "ZC3H7B", "ZCCHC11", "ZCCHC3", "ZMYND8"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..670688b629577b6647ab0f93cd12683a35af98d7 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:617a9d51188dffac3f9130442f35e14f737a4d853cb4de16d753bef124279b6b +size 77261 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5c6ad89e6eb4a9fd7829fc755d075522c55d600b --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 3.0 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8c07985fc92a66849e6b878c08523a3dcaaae14e --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3bcf3ca12716d11215f398d88ee9d5c25f6bafc3 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.373260179209296 0.3561474597197257 0.7217301365489059 0.9940039575391288 0.7217301365489059 8 P98194,P35670,Q9HD20 3 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..984945ed7c764a004efc7d8ffb3112df6f069911 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7B", "EIF5A", "FASN", "NOTCH2", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP2C1", "ATP7B"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..daffa54466a1c6257d97ac31b2c43979a11c9fb9 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ecd40aba04a5553a59513fb2ba68983c5c8eecd7d9be8d7879326fb9e39bc946 +size 188680 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..89347332fd727e794f5dc31a862dff01327a7f4e --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Tetratricopeptide repeat [IPR019734]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d152f6542ee5763521fce714be3f63d38c300fca --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc146cd62399a35304891d1e432dbdbf6825825f245276a448d2d3a9e2656531 +size 144842 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..62abf3a1c7ac395d64d8ec47b7d27fdd857db37a --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aa89fbb2a7ffd46a0e8a82a6f7c20f4ddc5bf95aca33149198f346697f12e404 +size 151208 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ff907fc2541df9987d5c60d2153cb0108bf89d7f --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8a4356da17f08ef8753602a6cb9d6769c665b2578acd402a23887d0af12949e +size 87508 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6ef1b82392aaebb4aa274a9228f7d67dbe213c46 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 5 20 2.293530096331017 0.021817504694535 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.036064976370089 0.1644315705571846 0.0513963234576887 0.0130060888805635 0.0095095891823194 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..642483646ae509295e30f60f123534994fa82ce9 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 81, + "title": "Average number of proteins per term", + "value": 5.716049382716049 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bf1f8a0ed029413ab334f94d13d4cdf59c0f543c --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4cc81999c00634e7e516beda1f41ae946f52894c --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.5845333223337227 2.293530096331017 0.021817504694535 0.8325015351600797 0.0930114673819651 20 O43772,Q9UJS0,Q9Y619,Q70HW3,Q9BQT8 5 +Spectrin repeat [IPR002017] 0.5121531500216332 1.054181297883449 0.2917999207911581 0.9999999999992712 0.5518843515252637 8 O43707,P12814,Q8WXH0,Q13813 4 +Tetratricopeptide repeat [IPR019734] 0.3125804540813915 0.8436660128725558 0.3988560647168344 1.0 0.6411224261461562 48 Q15006,O43765,Q13217,A0AVF1,O15460,Q9UJX3,Q9UGR2,Q6P2P2,Q6DKK2,Q9UJX2,P13674,Q6P3X3,Q14318,P49321,Q9H0B6 15 +Protein prenyltransferase, alpha subunit [IPR002088] 0.686240644789859 0.7154952902771979 0.4743030500260798 1.0 0.6716035835357711 3 P49354,Q7Z6K3 2 +PFTB repeat [IPR001330] 0.6572661870503569 0.6539226651952786 0.5131616307727549 1.0 0.6927682015432192 2 P49356 1 +Calponin repeat [IPR000557] 0.5059962808985743 0.1845341257869059 0.8535944583126609 1.0 0.9218820149776736 3 Q99439 1 +Tetratricopeptide repeat 2 [IPR013105] 0.3597350230414844 0.1159304228821687 0.907707684278765 1.0 0.930687625652911 5 Q6P3X3,Q02790,Q14318,P31948 4 +Kinesin light chain repeat [IPR015792] 0.4197372673748651 0.0532837423771672 0.9575058335027202 1.0 0.9575058335027202 3 Q9H0B6 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2f914df968b6259932519b07a799b49e4a001b43 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "KNL1 MELT repeat [IPR043651]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANKS1A", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "APC", "ARMC1", "ARMC6", "ARMC8", "ARMCX3", "ARPC1A", "ARPC1B", "ASPH", "BCOR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CHAF1B", "CIAO1", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COPA", "COPB2", "CORO1B", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DTL", "DYNC1I2", "EDC4", "EED", "EHMT1", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GIT1", "GLG1", "GLS", "GMPPA", "GMPPB", "GNB1", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HERC5", "HTT", "HUWE1", "IFIT5", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "JUP", "KAT7", "KDELC1", "KDELC2", "KDM2A", "KIDINS220", "KIFAP3", "KLC1", "KLC2", "KLC4", "KNL1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRCH2", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRSAM1", "LRWD1", "MACF1", 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0.0282547904280988 0.0656244339904668 0.0540767090111314 9.30136188832786e-06 2.335210357559597e-11 +Anion transport 19 74 3.807552858908767 0.0001403487462485 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 0.0001250529346548 0.0023851341481663 0.0001252183647456 0.0003568865728054 0.0002922195610233 +Organic acid transmembrane transport 12 33 3.6221144993938506 0.0002922047246449 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 2.80249150652954e-06 0.0543724481878489 0.0001144472789083 3.233709184205146e-06 0.0001176569873145 +Alternative mrna splicing via spliceosome 21 41 3.483471185889626 0.0004949563975986 14.009708737864075 40.728155339805824 0.0708159133159534 0.5694011596603432 6.451830696216548 3.032011011191426 1.225863726972057 0.3649890000258197 0.1249266923826934 1.0 0.4620800234731917 0.0001451869950716 2.950732285529002e-07 +Mitochondrial transport 32 92 3.474184898800528 0.0005124078058766 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 9.901179434347444e-05 1.2610802803762405e-05 4.782164622252979e-06 0.0008241549035924 2.3351594692880105e-05 +Anion transmembrane transport 12 46 3.466992793561957 0.000526316000271 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 5.655842687331236e-05 0.0155956893556562 9.714238185978128e-05 8.188374825428545e-05 0.0003355986872213 +Protein targeting to mitochondrion 17 50 3.4140825583684244 0.0006399718018539 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 0.0014867890599371 3.192618481319163e-06 0.0001940435749139 0.0053953153197205 8.232739661509709e-05 +Transmembrane transport 50 228 3.353916872487609 0.0007967629526612 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 4.250649426174354e-05 0.0007155395593198 0.0001285362081583 5.778853436448136e-06 6.329565364384183e-05 +Organic acid transport 14 48 3.3484502155957943 0.0008126487958983 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0003026425134392 0.1357968236714454 0.0020186844379805 0.0004857227802637 0.00272126093832 +Protein localization to mitochondrion 20 65 3.3331111141786542 0.0008588063681864 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 0.0011025103637559 1.0502153126795358e-05 0.0005873272870129 0.0012066818666679 6.359121675788395e-05 +Protein transmembrane transport 6 25 3.221185295577363 0.0012766158091284 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0005060278437631 0.0001068921937335 0.0016384890204764 0.0002678672315905 0.0138300064936424 +Protein targeting 34 121 3.204527020142916 0.0013528459156197 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 0.0011072428599653 0.0010814435001639 0.0104311471068346 0.000395332975748 1.3074198992740306e-05 +Negative regulation of mrna processing 12 23 3.1710282545265662 0.0015190036769585 7.699029126213592 21.66747572815534 0.1748680804835885 0.5472984180526073 3.879457852865703 1.8456483684321656 1.0884740123370542 0.3440194219213014 0.1003771830822555 1.0 0.2372212797486779 0.0294507732567689 3.941061696608172e-05 +Regulation of alternative mrna splicing via spliceosome 17 29 3.056139730034188 0.0022420674312255 10.609223300970871 30.575242718446603 0.1468114472042654 0.5502297177540902 5.108075880658377 2.6128265930148187 1.194088433027589 0.3536418549118582 0.2426036558357668 1.0 0.3777229935777695 0.0011113418092766 2.7871059860660337e-06 +Organic anion transport 11 49 3.015949517458981 0.0025617590683739 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 0.0210532035044858 0.1470901062438777 0.0124644356717177 0.0237635173186347 0.0484861136064748 +Negative regulation of mrna splicing via spliceosome 7 16 2.9818118714367685 0.0028654802334224 6.087378640776699 15.199029126213592 0.1078323316448317 0.4870213286066137 2.88823121239329 1.0677073837920623 1.2108018519405566 0.3438522963849697 0.0507436344096852 1.0 0.1677870330809631 0.0102137155300364 1.414656434197586e-06 +Protein transmembrane import into intracellular organelle 3 12 2.9093083985197747 0.0036222934307161 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0193974046888486 0.0003636173209342 0.0028960612595367 0.0056128198685199 0.0560616912320164 +Intracellular protein transmembrane transport 5 21 2.884545549892381 0.0039197904860179 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0016324979049606 0.0012094933792174 0.0091243340822671 0.0007016746800212 0.0210947346086547 +Rna stabilization 12 28 2.8644497665520183 0.0041773440577306 9.359223300970871 27.37621359223301 0.4792302048577673 0.5262457931829767 4.411160534464403 1.6856669427134765 1.0994939820726763 0.3614208213771557 0.0143014435112411 0.2068720246493716 0.0115248505447769 0.0304079267330467 1.7824094846844216e-05 +Negative regulation of rna catabolic process 18 35 2.829731862490608 0.0046587029940279 11.186893203883496 32.42718446601942 0.419853700893663 0.5432159718224696 4.924332595678975 2.3133296381008863 1.0980554146273172 0.3596399931743501 0.0050088609492012 0.2400196775334175 0.0181443698350236 0.0129296559640097 1.8042165381148847e-05 +Phospholipid catabolic process 4 12 2.8199393700539748 0.0048032723982667 2.8519417475728157 11.6626213592233 -0.4947797705004225 0.2407875191525107 1.5516734206570804 1.908148322767312 1.4202743542297325 0.210826310814772 0.0014210741798379 0.1155957163384056 0.0255840399150975 0.0033024410276518 0.0075753503172145 +Negative regulation of mrna catabolic process 9 26 2.8014458445296424 0.0050874179131652 9.169902912621358 24.631067961165048 0.5652120707700043 0.4958815262040553 4.097153521759381 1.8459627491120816 1.1372403168685192 0.3560626632344691 0.010670012652184 0.1916891885455893 0.0091243340822671 0.0230341265569123 4.717474112626933e-05 +Insulin receptor signaling pathway 16 32 2.76558394555528 0.0056820978330365 6.410194174757281 27.196601941747577 0.4458503447638467 0.5800076074910292 3.334752718036452 4.318360902053531 0.801520614655186 0.3231564676168196 0.0729306540338043 1.0 0.5484830827387088 0.1374400519295191 0.0458454406557164 +Negative regulation of autophagy 8 27 2.763387414887254 0.0057204823383287 5.063106796116505 24.313106796116504 0.449887145270975 0.5377284095479077 2.9855473971181983 2.929018368027943 0.8516059018543028 0.3205218740462018 0.1379711291481713 0.0395283360833688 0.1355867800667393 0.0789974698724344 0.1071972712501636 +Positive regulation of mrna processing 10 22 2.7264735181444384 0.0064015089197821 7.257281553398058 20.73543689320388 -0.0677041718348574 0.5626080634690505 3.882600018197884 1.2008922869485354 1.0164518882129698 0.3320351770060843 0.0018887893960436 0.0075879492488378 0.0023694947377154 0.0004989114687539 4.346622147922913e-06 +Protein import 32 85 2.6983704929963857 0.0069679843839358 18.941747572815533 84.88106796116504 0.6008949453203009 0.582747226306641 7.950789473798742 5.928615059974957 0.9194508312715092 0.3730411656244653 0.126009897559723 0.0094271760484152 0.0907183874210868 0.028253689956658 0.0505159831644612 +Peptide catabolic process 5 9 2.692260811085111 0.0070969421749662 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 2.3294731310246106e-05 0.0035263772514821 0.0007461625149634 7.054294597105141e-05 0.0002049367226 +Negative regulation of rna splicing 7 18 2.6882175413941805 0.0071834580961069 6.550970873786408 17.652912621359224 0.080708148531743 0.5352211753198439 3.085327637418694 1.454292695708865 1.0888581549716274 0.3350559056430555 0.0769843908651827 1.0 0.2070995190727305 0.0195244436529747 1.1085160867237355e-05 +Nuclear envelope organization 12 33 2.6800912553560696 0.0073602092050246 8.555825242718447 29.70873786407767 0.3742592988081523 0.5658154731413123 3.620906131367995 3.382223856109787 0.8839532199066901 0.3277754788938732 4.929583881454536e-05 0.2143583684675494 0.3896854720293997 0.0002096397492041 4.386525515453401e-06 +Rna splicing via transesterification reactions 81 191 2.677199104647112 0.0074240502609788 57.62378640776699 175.9247572815534 -0.5311319544097726 0.5586481823524154 19.183116495466795 10.962720088427156 1.3427529129902214 0.3667601092782501 0.0019937901942732 0.1314977741365594 0.0145543964999889 1.3155784555947737e-07 7.458495898185223e-13 +Circulatory system process 15 78 2.665725154119495 0.0076822470206858 17.152912621359224 72.00970873786407 0.7968086684699157 0.4206667688960129 5.8797345113877215 8.195718922280731 1.282615010632819 0.3676426088525382 0.0070382387260883 0.1050127227394533 0.008632132186118 0.0007998390624453 0.1330077859853712 +Positive regulation of oxidoreductase activity 4 11 2.6641333215943743 0.0077186964766673 2.179611650485437 8.660194174757281 0.9323097289205834 0.3351781724420858 1.467039765796201 1.084340415669104 0.8660275673035036 0.2662046996688798 0.0039111376132457 0.0110614955842043 0.0041517217414646 0.0012549484261259 0.0233089974379561 +Regulation of dna templated transcription in response to stress 5 13 2.6623731061382707 0.0077591819040696 2.8470873786407767 11.885922330097088 0.1387380176828835 0.4895467516437726 1.976418321285878 2.194232482701444 1.0022724956514792 0.2960877477393434 0.0048218288677721 0.1564797373419447 0.0003733671894444 0.0016346598494465 0.0072821786511837 +Smad protein signal transduction 6 9 2.6419708754719644 0.0082425143358042 2.9223300970873787 8.470873786407767 1.0610232243819884 0.2706100861951009 1.609675360071813 0.9712499271368484 0.9663464864325269 0.2495327076802485 0.0064388310937419 1.0 0.0538434207197609 0.0142235096743441 0.010788368915323 +Mitochondrion organization 63 202 2.60955974351596 0.0090658814089468 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 0.0002619960600078 0.0008639625494933 0.0237623949592503 0.0003582331575709 7.665853976274154e-05 +Tetrapyrrole metabolic process 7 19 2.6050465183222093 0.0091861786943459 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0014737667222467 0.0011325878612279 0.0085749794431607 0.0006205149914719 0.0002221540307242 +Porphyrin containing compound metabolic process 8 17 2.5589964504860374 0.0104974813233806 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.0005066149297173 0.0005765764868268 0.0045096021611559 0.0001711644149485 3.2730608309419086e-05 +Regulation of postsynaptic membrane potential 3 14 2.558552777763997 0.0105108863815093 2.4733009708737863 11.111650485436892 0.5657463373755282 0.4860434502535432 1.819998340098205 2.2081403224579756 0.8629150008491288 0.311233189592999 0.0048218288677721 0.1564797373419447 0.0466281418945222 0.0107757845080475 0.0962848984941054 +Chemical synaptic transmission postsynaptic 3 14 2.558552777763997 0.0105108863815093 2.4733009708737863 11.111650485436892 0.5657463373755282 0.4860434502535432 1.819998340098205 2.2081403224579756 0.8629150008491288 0.311233189592999 0.0043504308627301 0.1524760813950871 0.0443091130960601 0.0097601039903573 0.0888289826938022 +Peripheral nervous system development 4 14 2.5541016372171934 0.010646217494669 2.9757281553398056 11.519417475728156 0.6034295307069711 0.4690475043667866 1.8206990026194103 2.156973709389053 0.837829879270116 0.2915098257052096 0.009866678008158 0.1878492321971458 0.0666692325567911 0.0213813720021448 0.0614446561434308 +Positive regulation of rna splicing 10 23 2.545535212591264 0.0109110358653048 7.463592233009709 22.305825242718445 0.1184175596008347 0.5999000078688589 3.811216800921852 1.12287125395347 0.9928161550495398 0.3391592847788065 0.0027751979160182 0.0092510900433489 0.0031841845740684 0.000812960139445 8.789062803877673e-05 +Glial cell development 4 23 2.519171622576823 0.0117631305446452 5.114077669902913 20.08495145631068 0.342527471970151 0.5482793913252476 2.6656928412824445 3.2664916525364203 0.9072377099594536 0.3081373734674846 0.0071147866434086 0.2578448493622087 0.1226746045160812 0.0180040169030602 0.1921847889599738 +Ion transmembrane transport 35 165 2.5129261033203547 0.0119734412395993 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 0.014934503107679 0.1669355564057927 0.0122120396511153 0.007634461548638 0.0052213701289831 +Cellular response to amyloid beta 2 7 2.506941700207124 0.0121780796034733 1.8713592233009708 5.91747572815534 0.2206633711995859 0.4678383207618323 1.2867717931543454 1.328545973894273 1.1144604515178314 0.3257294628423651 0.0093323386517168 1.0 1.0 0.0173886328284286 0.09905667817091 +Response to amyloid beta 2 7 2.506941700207124 0.0121780796034733 1.8713592233009708 5.91747572815534 0.2206633711995859 0.4678383207618323 1.2867717931543454 1.328545973894273 1.1144604515178314 0.3257294628423651 0.0093323386517168 1.0 1.0 0.0173886328284286 0.09905667817091 +Macromolecule deacylation 13 42 2.5036367493249294 0.0122924166790996 8.196601941747574 37.97572815533981 0.0337115600431618 0.6979662528596892 5.054334687455092 4.721299928354385 0.6876836523582107 0.2889526377185229 0.0042758499800372 0.395163544863046 0.0189133156354044 0.004144931190839 0.0336318224351112 +Response to oxidative stress 17 98 2.502864147728403 0.0123192821241702 18.145631067961165 95.9757281553398 0.5057872201816154 0.5358657948719677 6.785060354870026 9.30128883458378 0.9511882590088212 0.3606217523881886 0.004296639387933 0.0484019731694876 0.0627959525445574 0.0007686896320591 0.0290484093484997 +Purine nucleoside metabolic process 4 9 2.501732508902475 0.0123587261506439 1.980582524271845 9.033980582524272 -0.561573150407665 0.256884982647158 1.1965207046214466 0.8088171151975914 1.3639961437518346 0.2190432338017035 3.950925220152876e-05 0.0043047615253927 0.0010099703116007 0.0001186481206876 0.002864460747413 +Inorganic anion transport 8 30 2.4966980273044723 0.0125355654752381 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.0003432382435751 0.0041267723764488 0.0043038530101662 0.0013505003452077 0.001762316825366 +Fatty acid transmembrane transport 3 8 2.48841245270322 0.0128314824806581 2.3519417475728157 6.720873786407767 1.487456141723218 0.1763040127694548 1.5547987465385102 1.1092073674791965 0.7935702169981724 0.2103298472796338 5.8094658902717255e-05 1.0 0.0056684159955205 0.000142755965642 0.0020183200628615 +Ribonucleoside metabolic process 4 8 2.482410753420867 0.0130496752469582 2.1189320388349513 8.12621359223301 1.1914157696469383 0.2635896161542528 1.2648845164842024 0.7462477223524518 0.9827848183963048 0.2624193088278075 7.87427409742689e-05 0.0056070915236824 0.0015052123544451 0.0002335266734922 0.0053032680205866 +Purine ribonucleoside metabolic process 4 8 2.482410753420867 0.0130496752469582 2.063106796116505 7.834951456310679 1.2047777662844132 0.2574288772305114 1.199068432200366 0.6246876870736083 0.9870596763535292 0.2611531847589775 1.279118279937529e-05 0.0028214739728005 0.0005309775927247 3.906142953800441e-05 0.0010238181908857 +Protein processing 16 47 2.4735530791303635 0.0133776930146491 12.08252427184466 45.980582524271846 0.9011703887478908 0.3916089016010577 4.43430858840224 4.931040148104543 1.176660792763282 0.3507158233798557 0.2785067994443859 0.4833603043022704 0.7411972663513849 0.2474616777336352 0.0180042278108211 +Protein import into mitochondrial matrix 1 9 2.460293882460885 0.0138823287484268 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0327528823448254 0.0021914548918381 0.0088504827764808 0.0498779046475234 0.1641299211995837 +Fat cell differentiation 8 27 2.4409227250505565 0.0146497891497012 5.640776699029126 26.395631067961165 0.292103738106274 0.6298117566529499 2.847599462303203 3.951929642936992 0.7652650842907566 0.3130614605725025 0.012639953812855 0.4606405324486534 0.3561708686960925 0.0385480470877788 0.1833350276114758 +Phosphatidylinositol 3 kinase signaling 8 17 2.4203009131831204 0.0155076683716122 3.5242718446601944 12.592233009708735 0.2057565975909978 0.5941804445034684 1.93383094909889 2.797144498191813 0.7839173658636757 0.2964688562102807 0.0475081480300579 0.2855170484549717 0.1487873266068847 0.0931141624023252 0.0216432397728663 +Inositol lipid mediated signaling 9 22 2.414769398668378 0.0157451745501397 4.339805825242719 16.79126213592233 0.1627670420337234 0.6351296521833775 2.3996496429475087 3.445148743279975 0.7306083436618722 0.2884815643674678 0.1101692569468587 0.3626106066392318 0.2319888267069046 0.1984756435735147 0.0915124164360535 +Rna splicing 79 246 2.413222272198024 0.0158121734219971 73.21844660194175 227.36165048543688 -0.5595293373386813 0.5630575519934683 24.43896398568791 13.966422466014652 1.2766368335479483 0.3596377513528329 9.724855019604216e-05 0.2549101813482316 0.0093840736975395 6.059524111960399e-09 2.1052909347810767e-14 +Collagen fibril organization 3 9 2.40841849633147 0.0160218032681587 2.75 8.449029126213592 0.7618465155681635 0.4237593014631459 1.546409872946248 1.4346015410823785 0.9057772992250752 0.3095171034083678 0.0943570240414836 0.1197698958477507 0.0274603336438859 0.0267619345648551 0.0402069493791732 +Negative regulation of gliogenesis 2 6 2.40440663330239 0.0161987435265416 1.3470873786407769 5.104368932038835 0.7908721225635217 0.3008340423028514 0.9967988871839628 1.1559387979758486 1.13650278668033 0.2567959459302846 0.0082299219600807 0.004721075682937 0.018640880521655 0.0153906222854723 0.0892170338783466 +Protein hydroxylation 4 15 2.3913921828155424 0.0167846129735071 5.04126213592233 14.87621359223301 0.7765678108992397 0.4273021352291809 2.482119818897232 1.8660787070180411 0.9906439819977368 0.3285418073460514 0.0769843908651827 0.1071891284628969 0.0219975904219434 0.0024379570615939 0.0053032680205866 +Lipid localization 24 81 2.3874504485164767 0.0169656896678371 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 0.0003347225666456 0.0198575553584506 0.0053334692213979 0.0009634786030379 0.0056297151391449 +Positive regulation of mrna splicing via spliceosome 9 17 2.3701422143811164 0.0177812443164262 5.868932038834951 16.20873786407767 0.0871896031470175 0.5437393324787213 3.2098612959239534 0.8533892220402522 1.0533370630695786 0.3337140371767123 0.0003280352666488 0.0031646532309382 0.0006327439593496 5.302129833761715e-05 8.553254679917977e-07 +Carboxylic acid transport 8 35 2.360055435411335 0.0182722043506853 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0516313674535067 0.3922727602504912 0.0801526286479979 0.0420396019683425 0.0700280573838956 +Vascular process in circulatory system 8 36 2.347635368786341 0.018893006519542 8.218446601941748 31.361650485436893 0.5302527350177477 0.4259259059419516 3.6564678051714665 4.365329555745678 1.181021277396986 0.3310828049268227 0.0200297858139263 0.0152275178253789 0.0219950308691545 0.0054752443246288 0.0917767700893373 +Peptidyl proline modification 8 38 2.344672529532307 0.0190437974654493 7.95873786407767 32.38106796116505 0.6521103584457676 0.5266525958057561 3.2591538539789924 3.194797169860135 0.931894104733149 0.3508680261875629 0.002395008164251 0.0221752921749746 0.0803922289273931 0.000162079776431 0.0005183300980067 +Mrna transport 35 80 2.3360872050980066 0.0194866970176117 22.820388349514563 74.85922330097087 -0.3243975063403491 0.6631560494995676 9.43741633253777 5.020307051554142 0.9410187854636848 0.3234443435490755 0.3652515030196219 1.0 1.0 0.0545097952893404 0.0003355986872213 +Regulation of gliogenesis 2 14 2.333879186770338 0.0196020488646604 2.5776699029126213 12.766990291262136 0.4275984781816435 0.4940387299474685 2.0387713813482975 2.058389810399436 0.9188590751221472 0.30630744557224 0.0710486005935812 0.0230307909848423 0.0832345551471358 0.1203869764331773 0.4430646629601374 +Positive regulation of nitric oxide synthase activity 3 5 2.333525776575519 0.0196205670722349 1.133495145631068 3.2257281553398056 1.2499027113696062 0.2397393339560919 0.765864203453703 0.836090186455318 1.0443138207064888 0.2366833109852498 0.0010300959297083 0.0011617774889038 0.0047533286028597 9.701143498590324e-05 0.0013990642028563 +Pigment metabolic process 8 29 2.329503982917457 0.0198323822487282 6.730582524271845 27.429611650485437 0.7330558837492486 0.3938325994367372 3.1680652652278396 2.973572406869117 1.1788232115476622 0.3357800616079686 0.0006189959987613 0.0021637050259114 0.0018806372047711 0.000338442961232 0.0002790542910114 +Peptidyl lysine hydroxylation 1 6 2.3223228736312462 0.0202155567995385 1.9077669902912624 6.308252427184466 0.5185432142936987 0.5039052199507211 1.4816803187819223 1.2712771097123454 0.8587843232642178 0.3110172359904222 0.0121098863456871 0.04159641685533 0.0031504918831051 0.0188064524051028 0.0680064706612652 +Organophosphate ester transport 7 29 2.321005308364334 0.0202865573554558 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 0.0654218965752266 0.0060275441501108 0.0402942577421927 0.1246036458142231 0.0380095176885234 +Organic cation transport 2 5 2.295407384585818 0.0217097885506221 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 0.0607884384663988 0.0944323477659319 0.0170518298819148 0.0135296171343662 0.0798154053066686 +Regulation of lipid transport 7 18 2.2933373685484284 0.0218285894219438 4.084951456310679 16.67718446601942 0.3665821344953645 0.5500608719110902 2.096012568417446 3.1783802180721676 0.8243482455883206 0.2999534514421824 0.0311024976150473 0.0343104139968933 0.1194965359594502 0.0629955787418294 0.0804683260329309 +Plasma lipoprotein particle clearance 3 12 2.256721498927878 0.0240254826023198 2.8033980582524274 11.597087378640778 0.2841472336869506 0.2922439265613805 1.7215617505529983 1.5431625772865891 1.3638326625090953 0.2354738993646769 0.3219766706732374 0.0901405579438761 0.1758008751515455 0.01180448121602 0.0144964406909979 +Enzyme linked receptor protein signaling pathway 32 145 2.2503098970306943 0.0244292801194399 25.24271844660194 117.68932038834951 0.1053848292396163 0.7149684279491084 9.284046259048107 15.168490031291515 0.7848849412953816 0.3313693252810506 0.4188482132010844 0.91982860360905 0.5663215010567435 0.6140200852171833 0.3220160267746322 +Positive regulation of lipid biosynthetic process 2 13 2.237721828541148 0.0252392008624919 2.1359223300970873 10.885922330097088 -0.8215246715859575 0.2430796532798289 1.3459651583750671 2.014292589159799 1.255322641842122 0.2284698722718244 0.036064976370089 0.1644315705571846 0.0513963234576887 0.063688713570506 0.2822516950414785 +Positive regulation of blood vessel endothelial cell migration 4 12 2.234900248621237 0.0254238982432966 2.6019417475728157 10.563106796116504 0.3237772908251186 0.4766826426301273 1.87906093994424 1.7813483652288025 0.94855386034594 0.2829738076650456 0.4735295928267487 1.0 1.0 0.1899587232036964 0.0747991773170861 +Embryonic digit morphogenesis 1 11 2.234174640369279 0.0254715843556974 1.4684466019417477 6.54126213592233 0.5989020645284063 0.4429704011231127 1.569266266788618 1.559731853735315 0.934963282113679 0.3039103680308826 0.2000246847682082 0.1839914155878272 0.3404254693467198 0.2797556636969028 0.6269975513332796 +Regulation of nucleobase containing compound transport 6 12 2.233993918615901 0.0254834732051867 3.7936893203883497 10.235436893203884 -0.0755175695248488 0.5839883836345571 2.245526076399216 1.3147433406725342 0.8376392375067842 0.3001788353881168 0.2231322746699767 1.0 1.0 0.2731207001200411 0.0028040242445346 +Positive regulation of monooxygenase activity 3 7 2.230440469666553 0.025718215404495 1.6844660194174756 5.415048543689321 1.0370130759472405 0.2898065983925483 1.0180179945339054 0.878583782950111 0.884976405150879 0.2417237008540366 0.0026839350013314 0.0021914548918381 0.0088504827764808 0.000371706641515 0.0049531384619904 +Vascular transport 5 16 2.2176481667647727 0.0265788309843202 4.774271844660194 13.094660194174756 0.7274519419599351 0.3186647470404632 2.3913310677559982 2.1617303908189505 1.2183781465172474 0.2807075669512824 0.0153171951264675 0.0230307909848423 0.0121763996061805 0.006984722202598 0.0336187943157164 +Regulation of dna binding 6 28 2.207783916272937 0.0272593397764693 5.288834951456311 25.783980582524272 0.0505315068205256 0.661274360409742 3.0737806962884457 2.432473606081504 0.6876690752190667 0.2837049878121863 0.0949746241749899 0.3472525306689195 0.5823300890010559 0.0060971418335812 0.1488121865857744 +Neutral lipid biosynthetic process 2 8 2.2063240031585023 0.0273613219065709 2.1067961165048543 6.288834951456311 1.1186547336258812 0.1821371148552785 1.2515048910859687 1.3298556757746482 1.2887117600293918 0.213034599641239 0.0943570240414836 0.1197698958477507 0.2297987482657219 0.1383652025719425 0.3817623273994432 +Positive regulation of lipid metabolic process 3 23 2.203554562765395 0.0275556857366252 2.9902912621359223 18.145631067961165 -0.6923656283003756 0.327811102660136 2.046759909896273 3.1070160723108415 1.1745388913123724 0.2783912514529492 0.0606532913314917 0.3056056721424713 0.1690424872723929 0.1163456461629851 0.5213801336363022 +Facultative heterochromatin assembly 6 20 2.2024298395522326 0.0276349600201779 5.883495145631068 14.451456310679612 -0.595318666977757 0.5045619407243719 3.1983034667633423 2.585447101394778 0.8561589089422644 0.3202484513141315 0.1065011954383621 0.1280604643503683 0.2445730022705269 0.0049571663496986 0.012132108209414 +Schwann cell development 2 10 2.202135772384666 0.0276557192733826 2.4150485436893203 7.487864077669903 0.0164677406559132 0.5754256017702141 1.6880697161478695 2.129849874141248 0.8900651354666074 0.3003336502630982 0.0093323386517168 0.1029565435856987 0.1993869387044997 0.0173886328284286 0.09905667817091 +Phosphatidylcholine metabolic process 3 12 2.202015148451437 0.0276642384372545 3.75 12.592233009708735 0.9144963280277142 0.2812959412325629 1.879404212556404 2.4412987678409657 1.1545250012369797 0.2602001877022786 0.0064388310937419 0.1683799151698467 0.0538434207197609 0.0142235096743441 0.1203149601397993 +Atp synthesis coupled proton transport 2 12 2.1995651321577 0.0278377633089506 4.067961165048544 11.769417475728156 0.4798560195228825 0.3249136059986872 2.5150503707528173 0.8937412640542226 1.340203957668315 0.2941072770431484 0.3219766706732374 0.0901405579438761 0.1758008751515455 0.3879443652654283 0.0708751155690715 +Glial cell proliferation 1 6 2.1810002791329617 0.0291833958363947 1.6262135922330097 5.412621359223301 1.1035845317400614 0.2421873681292294 1.0594430818589295 1.1842969002295405 1.0977939547178823 0.257309212646388 0.0714454283497719 0.1029565435856987 0.1993869387044997 0.1060727287920157 0.3097803043008575 +Protein adp ribosylation 3 13 2.172416427867655 0.0298242670055772 4.439320388349515 10.723300970873789 -0.4505346561484063 0.4968522141540497 2.561611204947478 1.5504903003735482 0.9005229933113351 0.305395974883262 0.0016433977549959 0.1197698958477507 0.0021303683071518 0.0038040834633598 0.0402069493791732 +Terpenoid metabolic process 6 20 2.1616711783053635 0.0306435307308614 4.992718446601942 17.42233009708738 0.6301104025923489 0.3704291423404849 2.365292196147205 2.02323551503238 1.1104102314092092 0.2862846297230793 0.0076955319238213 0.0158345246348345 0.0588586045542952 0.016869226769582 0.0033280295566654 +Regulation of centrosome cycle 9 21 2.161352169787965 0.0306681458316337 5.349514563106796 14.550970873786408 -0.4049270935814868 0.6062972703312597 2.936078680277183 2.518826978707793 0.7123951110518449 0.2953496296682568 0.214136639869363 1.0 1.0 0.0949405615621671 0.174947649934789 +Negative regulation of lymphocyte apoptotic process 3 6 2.158169649532649 0.0309146441805676 1.4368932038834952 4.827669902912621 0.5394724631500855 0.429843922437068 1.0942914798916792 1.2373285534927012 1.0763953212919928 0.3167022382829639 0.2812476453561096 1.0 0.1515272625734178 0.3411306657380243 0.0470360579614364 +Negative regulation of leukocyte apoptotic process 3 6 2.158169649532649 0.0309146441805676 1.4368932038834952 4.827669902912621 0.5394724631500855 0.429843922437068 1.0942914798916792 1.2373285534927012 1.0763953212919928 0.3167022382829639 0.3604088419145768 1.0 0.1993869387044997 0.4314443861210575 0.09905667817091 +Negative regulation of macroautophagy 6 13 2.1547256372133865 0.0311833103692227 2.657766990291262 11.342233009708735 0.5734063046472396 0.4235310399182105 1.9797182461289764 1.5349845399675808 0.9579244223739132 0.2955499758703153 0.4526232097391984 1.0 1.0 0.1724444479617574 0.0619922366647863 +Glycerolipid catabolic process 3 10 2.143476723405892 0.0320748381842155 2.313106796116505 9.682038834951456 -0.6906699682904549 0.2344337110397997 1.480134820103212 2.05940129824901 1.3437574149282263 0.2068175776304703 0.0193974046888486 0.1321770275159086 0.2518545844225215 0.0352396407582777 0.0560616912320164 +Schwann cell differentiation 2 11 2.1382241202637515 0.0324985576383751 2.728155339805826 8.487864077669903 0.0772419244875512 0.5793500773339586 1.8138848228668836 2.129849874141248 0.8733832080799478 0.3006049084677616 0.0160949565083758 0.1239247827595126 0.2372212797486779 0.0294507732567689 0.1539585868211262 +Protein maturation 16 72 2.134647923537792 0.0327897797530041 16.635922330097088 69.29611650485437 0.7279397561088901 0.5092233260742579 5.6828366082703345 6.923625268615643 1.0037762420957868 0.3621314209884535 0.1905473042961467 0.6163162766509123 0.8592353865109894 0.2153144790843455 0.0189682177282974 +Mrna splice site selection 11 21 2.134054781854712 0.0328382967479341 6.313106796116505 19.45631067961165 -0.0882007901962953 0.6106662837845365 4.074729493463986 1.85009419350405 0.8768494806167952 0.3199572041194961 0.4083005998785439 1.0 1.0 0.1383652025719425 0.0016034677277021 +Mitochondrial atp synthesis coupled proton transport 2 11 2.129497533571087 0.0332131187286122 3.9927184466019416 10.769417475728156 0.5022502301293951 0.29867761594221 2.4440229028906213 0.8937412640542226 1.3849431163992842 0.2834040324316194 0.2950874588528388 0.0814971443263516 0.1596960736798767 0.357118555081159 0.0544656750173612 +Regulation of mrna 3 end processing 9 20 2.1163002099539856 0.0343192829099932 6.733009708737864 18.68446601941747 -0.2999404033833792 0.6305592379674424 3.6974903151967418 1.703067323125468 0.6887917516345976 0.2867122938175264 1.0 1.0 1.0 1.0 0.7657233578788754 +Positive regulation of b cell activation 8 11 2.112413708882059 0.0346509801815035 3.092233009708738 11.186893203883496 0.1859276114166038 0.5045227221699764 1.8118375224733587 1.264344128777142 1.0073127631140006 0.3002532228225043 0.5406390866464361 1.0 0.3209553841799009 0.2526409373615763 0.1288473164062758 +Embryonic appendage morphogenesis 2 17 2.112299439482942 0.0346607739107855 2.3228155339805827 10.531553398058252 0.2830839749911006 0.5346739883331655 1.9546220638717424 2.634991297965238 0.8859883497178963 0.2947695295685748 0.209000423976626 0.0568079337981731 0.1862598674919939 0.3195580599455 0.5716036991382609 +Sterol homeostasis 6 12 2.104180715054844 0.0353626861120299 3.2597087378640777 11.594660194174756 0.7425754872590924 0.2773502445350785 1.6018884221780605 1.6170423171351411 1.3033948892752858 0.2615762483252933 0.1653357597547718 0.0136970422924113 0.0513963234576887 0.2345960405017343 0.2822516950414785 +Regulation of sterol transport 1 8 2.102867041435641 0.0354773936018735 2.2645631067961167 7.949029126213592 -0.2660435952469734 0.4696867674075412 1.5281839445392789 1.3346844393150472 0.977377779136872 0.2786928507413737 0.1319153679526289 0.0104419310742173 0.0398064357050217 0.1899587232036964 0.4830287271925335 +Low density lipoprotein particle clearance 3 11 2.100931174771088 0.0356470083443563 2.628640776699029 10.633495145631068 0.2652848599989675 0.2775304047094778 1.52978680445189 1.394909057645927 1.3932465899654711 0.2286950604253255 0.2671375230127674 0.0727733471903131 0.1432798584585485 0.0062267265321947 0.0063533232968262 +Regulation of striated muscle cell differentiation 4 13 2.100276377111024 0.0357045360614773 3.3592233009708736 10.609223300970871 0.2787167098340025 0.6120605082066465 2.5631987332731696 2.4035193408793982 0.7366004751948119 0.29286917084059 0.5406390866464361 1.0 0.3209553841799009 0.2526409373615763 0.0435237537141962 +Positive regulation of nuclear division 2 15 2.096470892131859 0.0360404394102655 3.968446601941748 11.99271844660194 -0.0337553343960273 0.6937466258729355 2.3977081521884553 2.163789688008418 0.6374809594980775 0.2708234828163465 0.0884470864963728 0.1155957163384056 0.2223047329091382 0.1300982938321277 0.1309583783231107 +Regulation of glial cell proliferation 1 5 2.0945361418732444 0.0362122470046206 0.9563106796116504 4.089805825242719 0.9341050469143442 0.3274204875894432 0.8829748814899869 0.9675276073756384 1.0425311720733597 0.2839327622585455 0.0413755654688228 0.0771453392642774 0.1515272625734178 0.062605312422627 0.1998160014011807 +Microtubule organizing center organization 17 52 2.0941758810005147 0.0362443154818492 10.985436893203884 40.730582524271846 0.0531780861213523 0.6579413251048066 5.115632006755549 6.500017673649269 0.8024863779803786 0.3148854550379723 0.2446093169548854 1.0 1.0 0.0985495091000189 0.1890228326658032 +Negative regulation of cellular catabolic process 30 100 2.093969753557825 0.0362626747184096 19.81553398058253 90.747572815534 0.0733496829412586 0.7250307274927189 7.827630390507636 7.261373331021129 0.65098001342687 0.3014089856109174 0.0164847249606671 0.0700360595534253 0.0457497734465388 0.0259314359531412 0.0003604537446259 +Regulation of glycoprotein metabolic process 6 12 2.08997960352288 0.0366196319486229 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 1.0 1.0 1.0 0.4972078859355511 0.1539585868211262 +Xenobiotic metabolic process 2 13 2.089662960641028 0.0366480864608234 3.361650485436894 12.766990291262136 0.2888989680701592 0.4079174523039034 1.7314299590460738 2.070147893479259 1.0739221767516711 0.2525712773999662 0.0410866703643027 0.1723099894081314 0.0065760397653667 0.0720513532108381 0.3092787829323835 +Glycerophospholipid catabolic process 3 7 2.088778226816981 0.036727691249353 2.216019417475728 7.563106796116505 0.8419758607208171 0.2558936783676348 1.405411068501889 1.391164232085279 1.2384126210044872 0.2497846504551273 0.003256901879322 0.0727733471903131 0.1432798584585485 0.0062267265321947 0.0063533232968262 +Positive regulation of adaptive immune response 9 16 2.075501181786098 0.0379401094488687 4.638349514563107 16.04126213592233 0.0444780909393623 0.5363245981420569 2.2998069134178674 2.0207050483556 0.953162271864993 0.3079428375592325 0.6503846921300606 1.0 0.4072036678679048 0.3776649172031714 0.4939569265883401 +Cytochrome complex assembly 4 13 2.0739054103444063 0.0380880964848795 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0039111376132457 0.0110614955842043 0.0041517217414646 0.0088087297166582 0.0233089974379561 +Modulation of excitatory postsynaptic potential 1 5 2.0696050500138976 0.0384893447750569 0.8616504854368932 4.184466019417476 0.8716049128546732 0.3904030169730884 0.8964791942932838 0.8154761884284932 0.955782621454512 0.3079648786148587 0.0413755654688228 1.0 0.1515272625734178 0.062605312422627 0.1998160014011807 +Positive regulation of mrna metabolic process 15 71 2.063629662576228 0.0390528429432361 17.91747572815534 63.4247572815534 -0.1303459782637173 0.6455677617407789 7.627427860293009 4.983630357784323 0.7848480579932345 0.3072284024535978 0.0607150104129523 0.0944907526770622 0.0892411854271464 0.0173348540530166 7.971186223718879e-05 +Protein peptidyl prolyl isomerization 5 29 2.062786146565686 0.0391329508209763 5.805825242718447 24.152912621359224 0.2517409431057898 0.5902438884006979 3.2955051837407017 2.757763315973305 0.91993420852781 0.3179002106692878 0.0005792468221625 0.0123481232007499 0.0466281418945222 0.0016346598494465 0.0072821786511837 +Appendage morphogenesis 2 18 2.0587545384802985 0.0395177587206516 2.733009708737864 12.356796116504857 0.1736162467757523 0.5679910710115588 2.1781299697112395 2.7670701317045303 0.8540375906091052 0.2978148567402963 0.2861788319783708 0.0762203496734667 0.2391023108138102 0.4186732079295251 0.7027360525677749 +Organic hydroxy compound transport 9 31 2.0565830686980244 0.0397263482541627 7.145631067961165 30.32766990291262 0.3121985122058121 0.5028073494895335 3.2773354290298986 4.4061862301676955 1.0194405540894098 0.3270691777029814 0.058829985031924 0.0145062062606783 0.020727790300862 0.0489196207839397 0.281557453352205 +Response to light stimulus 10 67 2.053771514722017 0.0399978111549861 12.70873786407767 56.38106796116505 0.0070300704017528 0.7633564533174257 6.037714908774202 7.441873839168449 0.5541923286861473 0.2639102378917758 0.0033861916485512 0.2215319004109305 0.2704786451153059 0.0060245074428593 0.1289615277198751 +Membrane lipid biosynthetic process 4 27 2.0518586265905694 0.040183403721768 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 0.0729306540338043 0.3219228357858488 0.1862598674919939 0.0485304500002844 0.2097414112479707 +Cellular response to biotic stimulus 11 42 2.046786423648032 0.0406790592465797 8.070388349514563 35.616504854368934 0.7964477296470692 0.4798420500319036 3.1871094803090645 3.824235365857021 0.8467616012566905 0.3489796792314515 0.0060586199766527 0.0159688820707086 0.0045866083337414 0.0198065600649204 0.0088483081667491 +Regulation of lymphocyte apoptotic process 3 10 2.0428849597733088 0.0410638275239727 2.029126213592233 7.381067961165049 0.4739111260724032 0.458828678896727 1.5277771827044868 1.703203955440417 1.0212880846326546 0.3148137372778026 0.3966730600330987 1.0 0.2223047329091382 0.4718643991127431 0.1309583783231107 +Regulation of fatty acid transport 3 6 2.0303042464002 0.0423256228559627 1.3810679611650485 4.548543689320389 0.6157357570119139 0.4735209512695758 1.030096057940794 0.7883082633044994 0.8644473952298549 0.3082995501275736 0.014947386852539 1.0 1.0 0.0231366382468947 0.0009257875785001 +Transition metal ion transport 9 16 2.026876926030039 0.0426750008069858 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 0.682892698243545 1.0 1.0 0.1714591409165242 0.0664517794665692 +Positive regulation of leukocyte proliferation 6 17 2.019369877893187 0.0434487899181514 3.861650485436894 14.71359223300971 0.6007881424807215 0.4761380762722816 1.9750347653754128 2.1890082226375087 0.9342511129724644 0.3127219346815347 0.1003207197813801 1.0 0.107004894081217 0.1655021226103433 0.3129479757165558 +Membrane protein proteolysis 7 12 2.015097806676859 0.0438944020192386 4.138349514563107 11.781553398058252 1.0093176076341577 0.3069750059979975 2.078037067185485 1.3902746514167437 1.0484204695389652 0.2877212872591311 0.1790900895171192 1.0 0.3209553841799009 0.2526409373615763 0.3092787829323835 +Regulation of peptidyl threonine phosphorylation 2 11 2.0136900788928616 0.0440420822900127 2.563106796116505 8.009708737864077 0.03818910591028 0.5293686155535875 1.8704129802666387 1.424440926820526 0.934047724902416 0.3020531226500109 0.0884470864963728 0.1155957163384056 0.2223047329091382 0.0242110622206542 0.1309583783231107 +Steroid metabolic process 16 72 2.007890878149939 0.0446548887264328 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 0.0104329284304046 0.0007920633951553 0.0171014477496401 0.0135728765206948 0.0200125426146435 +Regulation of rna export from nucleus 5 11 2.0034032242943938 0.0451340256714267 3.638349514563106 9.516990291262136 -0.1000785089757399 0.5618225409730601 2.180626344993646 1.1308569952010117 0.8835605969950311 0.3064943312074072 0.2078873733672205 1.0 1.0 0.2550529546148332 0.0182159139614431 +Glycosyl compound catabolic process 3 10 1.99878383919992 0.0456317470979223 3.216019417475728 9.74271844660194 -0.2866012386822237 0.2471021044870933 1.8641835401772064 0.9067280280460008 1.4904201092322935 0.2120144867281597 0.0105168407066085 1.0 0.0219975904219434 0.0195244436529747 0.0272826327042602 +Centriole assembly 6 12 1.997380594076994 0.0457838542771562 2.320388349514563 7.703883495145631 0.0981091302442458 0.5997008732262058 1.7761286155268692 1.6219622737581103 0.7702273875411833 0.2808997267914532 0.5406390866464361 1.0 1.0 0.2526409373615763 0.3092787829323835 +Ion transport 39 218 1.9962248105574656 0.0459094580211534 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 0.004997617981256 0.0749659506094906 0.0178991825176604 0.002907801834208 0.0163466437734398 +Amyloid precursor protein biosynthetic process 3 5 1.9863444813779592 0.046995086721731 1.529126213592233 4.050970873786408 0.5724883308647799 0.4003128139433519 1.0007891127244537 1.1319816926742772 1.117383900072293 0.3129811194531851 1.0 1.0 1.0 0.1981219124770219 0.0680064706612652 +Vitamin transport 2 9 1.985410398974688 0.0470988299421077 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0769843908651827 0.1071891284628969 0.2070995190727305 0.1139407547181512 0.1093101132411038 +Sterol transport 7 24 1.9821975723000445 0.0474571322966832 5.516990291262136 23.23058252427185 0.3564989162781894 0.4550431454343515 2.7566693478017315 3.339632072416373 1.1016145306573315 0.3225081354886266 0.0415966028762325 0.0039603320298963 0.0275216398495969 0.0824194625829831 0.2364098572110782 +Nucleolar chromatin organization 2 8 1.9818537879403573 0.0474956073614429 2.4441747572815533 4.864077669902913 -0.6335115225329127 0.4691600222135045 1.4512432060982403 1.3674335942721625 0.9304432912780984 0.3188912874322187 0.014947386852539 0.0461123069087121 0.0921025797166938 0.001485709034831 0.010684483318579 +Regulation of b cell mediated immunity 9 11 1.9605254884263568 0.049934401838694 3.6310679611650487 10.941747572815531 -0.2262823982680208 0.5353342457163944 2.2800966223017314 0.9786581135773657 0.9161373302920904 0.3120819864892412 1.0 1.0 1.0 0.5329697587184232 0.450369534817547 +Regulation of isotype switching 9 11 1.9605254884263568 0.049934401838694 3.5728155339805827 10.650485436893204 -0.2172905213059532 0.5385447197496226 2.299649368577626 0.7999846826698388 0.9187928565939126 0.3116798414486451 1.0 1.0 1.0 0.4452488918515388 0.3280048671308403 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ab9d73263101e6abfcabf646db15bcb840a3a13c --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 6589, + "title": "Average number of proteins per term", + "value": 20.767491273334347 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b003bbcc16da7d9556687a7744e00f00a9bebc04 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..431591908e113635494bb6f8b87618d5b7dfea63 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1982 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Regulation of rna splicing 0.5529847307798184 4.428154762511093 9.504269747218077e-06 0.0607033523374923 0.0208745444548088 89 P51116,Q07955,Q9Y2W1,Q9UHX1,P19338,Q8IY67,P98175,P22626,Q13595,Q14320,Q8IXT5,P98179,Q14011,Q92841,Q96PU8,P62995,Q07021,P38159,P49761,P31942,P35637,Q96E39,O75494,O75525,Q01130,P52597,P51114,O75312,P52756,Q8WXF0,Q13242,P55795,Q96EP5,Q15427,P31943,Q07666,P61978,Q15007 38 +Mitochondrial transmembrane transport 0.6307733492643791 4.244445893349013 2.1913423210673244e-05 0.1344491271889299 0.0279602070952361 51 Q99595,P21796,O75964,O60830,Q9Y619,P06576,Q9UJS0,O43772,P00846,P23786,Q9BQT8,O95831,Q8IYU8,Q96NB2 14 +Regulation of mrna processing 0.5358158444906795 4.210675673505737 2.546080476117929e-05 0.1544461125659307 0.0279602070952361 88 P51116,O75150,Q9Y2W1,Q9UHX1,P18615,P50750,P19338,Q8IY67,P98175,P22626,Q13595,Q5VTR2,P98179,Q14011,Q92841,Q96PU8,P62995,Q07021,P38159,Q96ST2,Q96E39,O75494,Q8N7H5,O75525,Q01130,Q6PJT7,P51114,Q15637,P52756,Q8WXF0,Q13242,Q96EP5,Q8N684,Q9BWF3,Q15427,Q07666,Q15424,P61978,Q15007 39 +Regulation of mrna metabolic process 0.4379225163700515 4.0235719290112995 5.732206626118952e-05 0.3145679572113452 0.0419661216216649 161 P51116,O60506,O75150,A2RRP1,Q9UHX1,P18615,Q9Y2W1,Q8NC51,Q9Y5A9,Q13464,P50750,P07910,P19338,Q9P2K5,Q13148,Q8IY67,P98175,Q969T7,Q53R41,P22626,Q13595,Q5VTR2,Q96MU7,P98179,Q14011,Q99729,Q13573,Q13151,Q13868,Q7Z739,Q92841,P09651,Q96PU8,P62995,Q07021,P38159,Q96ST2,P31749,Q15717,P67809,Q06787,P08670,P35637,Q96E39,P52272,O75494,Q14103,Q8N7H5,O75525,Q01130,Q6Y7W6,Q6PJT7,Q92804,Q92945,P51114,Q15637,P52756,Q8WXF0,Q13242,Q96EP5,Q8N684,Q9BWF3,O95453,Q15427,P61978,Q07666,Q15424,P52948,Q15007 69 +Negative regulation of mrna metabolic process 0.5959836828017518 3.837904675187011 0.0001240886319355 0.5585412649686213 0.0711352222332207 48 O60506,O75150,Q9Y2W1,P18615,Q13148,P98175,P22626,Q5VTR2,Q14011,Q99729,Q13151,Q07021,P38159,P67809,P35637,O75494,Q6PJT7,Q92804,Q8WXF0,Q13242,P61978 21 +Regulation of mrna splicing via spliceosome 0.5356757028840561 3.820908657499483 0.0001329608935549 0.5836119224858473 0.0711352222332207 64 P51116,Q9Y2W1,Q9UHX1,P19338,Q8IY67,P98175,P22626,Q13595,P98179,Q14011,Q92841,Q96PU8,Q07021,P62995,P38159,Q96E39,O75494,O75525,Q01130,P51114,Q15637,P52756,Q8WXF0,Q13242,Q96EP5,Q9BWF3,Q15427,Q07666,P61978,Q15007 30 +Anion transport 0.51315779185109 3.807552858908767 0.0001403487462485 0.6033983051314784 0.0711352222332207 74 P21796,Q9UHG3,Q9BQT8,P08183,O00400,P41440,Q9Y619,Q99808,P30536,O43681,Q14728,Q9UJS0,Q9C0H2,Q15043,P30825,P45880,Q96NB2,P53985,P33527 19 +Organic acid transmembrane transport 0.6528775342217666 3.6221144993938506 0.0002922047246449 0.8542144075883856 0.1153314846748592 33 P31751,P08183,O43772,Q9Y619,P41440,P30825,P33527,P23786,P53985,Q9BQT8,P31749,Q96NB2 12 +Alternative mrna splicing via spliceosome 0.5938589626997611 3.483471185889626 0.0004949563975986 0.9616911777301822 0.1368162989711646 41 P51116,Q07955,Q9Y2W1,Q9UHX1,Q8IY67,P98175,Q92841,O95391,P62995,P38159,Q96I25,P23246,P52272,O75525,Q01130,P51114,P52756,Q8WXF0,Q13242,Q07666,Q15007 21 +Mitochondrial transport 0.4725967199787059 3.474184898800528 0.0005124078058766 0.9658543588080596 0.1368162989711646 92 Q99595,O75964,O60830,P06576,P00846,Q5JRX3,Q9NS69,Q9P0J0,Q9UBX3,O95831,Q10713,O14925,P55786,Q15070,O95429,O00165,P30536,Q9Y5Y0,Q9UJS0,Q99797,O75431,Q3ZCQ8,P23786,P45880,Q9Y3D6,Q8N4H5,O43615,Q9UII2,O43772,Q96EP0,O14737,Q9Y512 32 +Anion transmembrane transport 0.5648506768993969 3.466992793561957 0.000526316000271 0.968845888457774 0.1368162989711646 46 P21796,P08183,Q9Y619,P41440,P30825,Q9UHG3,P45880,P53985,Q9BQT8,P33527,Q96NB2,Q14728 12 +Protein targeting to mitochondrion 0.5458978992557536 3.4140825583684244 0.0006399718018539 0.9852737562330276 0.1368162989711646 50 P55786,Q99595,Q9UII2,O60830,O95429,O00165,Q5JRX3,P30536,Q3ZCQ8,Q9NS69,O14737,Q9P0J0,Q9Y3D6,Q9Y512,Q8N4H5,O95831,Q10713 17 +Transmembrane transport 0.4118888175730671 3.353916872487609 0.0007967629526612 0.9947627758222196 0.1368162989711646 228 Q99595,P21796,O75964,O60830,P06576,Q99523,P00846,Q96ES6,Q9UHG3,Q9NS69,Q9BQT8,Q8WTV0,O95831,P13073,P08183,Q13423,Q9Y619,P41440,O00400,Q99808,Q9Y5Y0,P31749,P46934,Q14728,P31751,Q9UJS0,Q9C0H2,O75381,Q15043,P30825,Q16625,P23786,P45880,Q9HD20,Q8IYU8,Q9BSK2,Q96NB2,O43772,Q70HW3,Q6ZWJ1,P0DP25,Q8IXU6,Q9H2V7,P53985,Q15629,Q8NEW0,O75844,P33527,P05067,P05771 50 +Organic acid transport 0.5442024413718557 3.3484502155957943 0.0008126487958983 0.9952836485539944 0.1368162989711646 48 P31751,P08183,Q9UJS0,O43772,Q9Y619,P41440,P30825,P33527,P23786,P53985,Q9BQT8,Q9Y3D6,P31749,Q96NB2 14 +Protein localization to mitochondrion 0.4879074999323937 3.3331111141786542 0.0008588063681864 0.9965213340458172 0.1368162989711646 65 Q99595,O60830,Q5JRX3,Q9NS69,Q9P0J0,O95831,Q10713,P55786,Q15070,O95429,O00165,P30536,P31749,Q3ZCQ8,Q9Y3D6,Q8N4H5,Q9UII2,P0DP25,O14737,Q9Y512 20 +Protein transmembrane transport 0.6652209395946298 3.221185295577363 0.0012766158091284 0.9997789220812088 0.1368162989711646 25 P31751,Q99595,O60830,Q9NS69,Q15629,O95831 6 +Protein targeting 0.4152995841784148 3.204527020142916 0.0013528459156197 0.9998663032990758 0.1368162989711646 121 Q99595,O60830,P46379,Q99523,Q5JRX3,Q9NS69,O60725,Q9P0J0,O95831,Q10713,Q9H9H4,P55786,O95429,O00165,P30536,Q9H444,O43681,Q9UHB9,P46934,P31751,Q14108,O75381,Q3ZCQ8,Q9Y3D6,Q8N4H5,Q9UII2,O43765,Q6ZWJ1,P56589,O14737,P43307,Q9Y512,P40855,Q15629 34 +Negative regulation of mrna processing 0.6708459767017213 3.1710282545265662 0.0015190036769585 0.9999553351880844 0.1368162989711646 23 Q5VTR2,O75150,P18615,Q8WXF0,Q13242,O75494,Q07021,P38159,P61978,Q6PJT7,P98175,P22626 12 +Regulation of alternative mrna splicing via spliceosome 0.6139915203579167 3.056139730034188 0.0022420674312255 0.9999996224519953 0.1368162989711646 29 P51116,P51114,Q9Y2W1,Q9UHX1,Q01130,P52756,Q8WXF0,Q07666,Q9BWF3,Q92841,P09651,P62995,P38159,O75525,Q8IY67,P98175,Q15007 17 +Organic anion transport 0.5083193963397109 3.015949517458981 0.0025617590683739 0.9999999542963656 0.1368162989711646 49 Q9UJS0,O00400,P41440,Q9Y619,Q99808,P30825,P53985,Q9BQT8,P33527,Q96NB2,Q14728 11 +Negative regulation of mrna splicing via spliceosome 0.7409193341200883 2.9818118714367685 0.0028654802334224 0.9999999938557682 0.1368162989711646 16 Q13242,O75494,Q07021,P38159,P98175,P22626,P61978 7 +Protein transmembrane import into intracellular organelle 0.7666234774578349 2.9093083985197747 0.0036222934307161 0.9999999999587192 0.1529517621211235 12 O95831,Q99595,O60830 3 +Intracellular protein transmembrane transport 0.6593300361778534 2.884545549892381 0.0039197904860179 0.9999999999942294 0.1529517621211235 21 P31751,Q99595,O60830,Q15629,O95831 5 +Rna stabilization 0.5960008270467791 2.8644497665520183 0.0041773440577306 0.99999999999895 0.1529517621211235 28 O60506,P67809,Q9Y2W1,Q14011,Q13151,Q08J23,P35637,O95453,Q9H814,Q13148,Q92804,P98175 12 +Negative regulation of rna catabolic process 0.5433357169588994 2.829731862490608 0.0046587029940279 0.9999999999999566 0.1529517621211235 35 O60506,Q15717,P67809,Q9Y2W1,Q14011,Q99729,Q13151,Q96HR8,Q08J23,Q06787,P35637,O95453,Q14103,Q9H814,Q13148,Q92804,P98175,A2RRP1 18 +Phospholipid catabolic process 0.7499812568316524 2.8199393700539748 0.0048032723982667 0.9999999999999832 0.1542406925967427 12 Q8WTV0,Q8NCC3,Q8IY17,Q8NHP8 4 +Negative regulation of mrna catabolic process 0.600544088414778 2.8014458445296424 0.0050874179131652 0.9999999999999974 0.1603019533152153 26 O60506,Q14011,Q9Y2W1,Q99729,Q13151,P35637,Q13148,Q92804,P98175 9 +Insulin receptor signaling pathway 0.5547738537615108 2.7655839455552793 0.0056820978330365 1.0 0.1649310247659809 32 P31751,Q9UQB8,P25054,P18031,Q6ZWJ1,Q15043,Q9UKG1,Q9BZF1,Q9H1E3,Q9H2Y7,Q9HCD5,Q8TBX8,Q96EB6,P31749,P05771,P43490 16 +Negative regulation of autophagy 0.5892750253237866 2.763387414887254 0.0057204823383287 1.0 0.1652034093793307 27 Q9NRR5,Q8IXJ6,P30536,Q9H444,O15118,Q08379,P09601,P31749 8 +Positive regulation of mrna processing 0.6216951512770182 2.7264735181444384 0.0064015089197821 1.0 0.1652034093793307 22 P98179,Q14011,Q9Y2W1,Q96EP5,Q96E39,P62995,Q8N7H5,P38159,Q15427,Q13595 10 +Protein import 0.4191763186008415 2.6983704929963857 0.0069679843839358 1.0 0.1719429279666 85 Q99595,O60830,P35658,Q9NS69,Q13501,Q13148,O95831,O14925,P02545,P49790,Q9UKG1,P49792,P31749,P37198,Q92973,Q15717,Q99567,Q9BVL2,O75381,Q7Z4Q2,Q3ZCQ8,Q14978,P52292,O43615,Q8N1F7,O75312,P56589,O14737,P57740,Q9Y512,P40855,P52948 32 +Peptide catabolic process 0.8142236295010676 2.692260811085111 0.0070969421749662 1.0 0.1719429279666 9 P55786,P42892,Q9UIQ6,P09960,Q9NZ08 5 +Negative regulation of rna splicing 0.6680550773555577 2.6882175413941805 0.0071834580961069 1.0 0.1719429279666 18 Q13242,O75494,Q07021,P38159,P98175,P22626,P61978 7 +Nuclear envelope organization 0.5369920410758057 2.6800912553560696 0.0073602092050246 1.0 0.174703811319962 33 Q8IXJ6,Q9ULX6,Q9H444,Q9Y2U8,Q86XL3,Q13148,Q9HD42,Q9UH99,O75844,P05771,Q8N1F7,P20700 12 +Rna splicing via transesterification reactions 0.3682137172492088 2.677199104647112 0.0074240502609788 1.0 0.174703811319962 191 O75940,Q86V81,P98179,Q14011,O75400,Q92841,P38159,Q96PK6,P31942,Q96I25,P23246,P52272,P55081,P52597,P62312,Q15427,P31943,P51116,P19338,Q8IY67,O60828,P22626,Q9Y2W2,Q15459,O95391,P62310,P62995,O75475,Q16637,Q96E39,P78332,O75525,Q01130,Q92945,Q86UA1,P51114,Q15637,P52756,Q13242,Q9BWF3,Q96DF8,P51991,O95400,Q07666,P61978,P52948,O60506,Q07955,Q9UHX1,O43390,Q13123,Q9UBB9,P98175,Q13595,P09651,Q96PU8,O75934,Q07021,Q9Y3B4,Q96RS0,Q99590,Q15020,Q06787,O60508,O75494,Q12874,Q9P013,Q8WXF0,Q8WWY3,Q92917,P38432,O43290,Q15007,Q9Y2W1,Q14562,P07910,Q96MU7,Q6NZY4,Q13573,Q96EP5,O00566 81 +Circulatory system process 0.4196095541237565 2.665725154119495 0.0076822470206858 1.0 0.1788633414109513 78 P08183,O75844,P0DP25,Q99808,P42892,P30825,Q9HB40,Q16625,P53985,Q9UIQ6,P09601,P00813,P33527,P42785,Q9NZ08 15 +Positive regulation of oxidoreductase activity 0.7553961305720831 2.6641333215943743 0.0077186964766673 1.0 0.1790791939604264 11 Q9NTG7,P31749,Q8WTV0,P00374 4 +Regulation of dna templated transcription in response to stress 0.7130689608603655 2.6623731061382707 0.0077591819040696 1.0 0.1793868405821578 13 P51812,Q8IXJ6,Q15418,P09601,P46934 5 +Smad protein signal transduction 0.8038320708837462 2.6419708754719644 0.0082425143358042 1.0 0.1876840180012644 9 P53999,P09874,O00400,P08670,Q9UIQ6,Q8N1F7 6 +Mitochondrion organization 0.3669647257158063 2.60955974351596 0.0090658814089468 1.0 0.1991169753451686 202 Q99595,P21796,Q9Y375,O60830,Q9Y2S7,O43676,O60313,Q8N163,Q5JRX3,Q9NS69,Q9P0J0,Q13501,Q9Y2R0,O95831,Q96EY1,Q13505,Q10713,O14925,P55786,Q15070,Q04837,P02545,O95429,Q9NUQ9,Q8N183,Q69YU5,P30536,O00165,P27544,Q8IWA4,P31749,Q00059,Q9H061,Q99797,Q9Y4P1,Q5XKP0,O75431,Q3ZCQ8,P45880,Q9Y3D6,Q7KZI7,Q9NVT9,Q9NQG6,Q8N4H5,O96000,Q92830,O43615,Q9BSK2,Q16891,Q9UII2,P09874,O75489,P0DP25,O95169,P14406,Q9NX63,Q9UDX5,Q96EP0,O14737,Q5TC12,Q9Y512,Q6DKK2,Q7Z3C6 63 +Tetrapyrrole metabolic process 0.642996734818683 2.6050465183222093 0.0091861786943459 1.0 0.2010863634440003 19 P30519,P22830,P30536,Q9Y5Y0,P09601,P33527,O00264 7 +Porphyrin containing compound metabolic process 0.6585325712716437 2.5589964504860374 0.0104974813233806 1.0 0.2169024104892114 17 P36551,P30519,P22830,P30536,Q9Y5Y0,P09601,P33527,O00264 8 +Regulation of postsynaptic membrane potential 0.6865480595097238 2.558552777763997 0.0105108863815093 1.0 0.2169024104892114 14 Q99808,Q9UQB8,P05067 3 +Chemical synaptic transmission postsynaptic 0.6865480595097238 2.558552777763997 0.0105108863815093 1.0 0.2169024104892114 14 Q99808,Q9UQB8,P05067 3 +Peripheral nervous system development 0.6857788410825693 2.5541016372171934 0.010646217494669 1.0 0.2178507051937102 14 P31751,P31749,P21266,Q8IXJ6 4 +Positive regulation of rna splicing 0.5821486768163671 2.545535212591264 0.0109110358653048 1.0 0.2225783755928594 23 P98179,Q14011,Q9Y2W1,O75312,Q96EP5,Q96E39,P62995,Q15427,P38159,Q13595 10 +Glial cell development 0.5785437219529415 2.519171622576823 0.0117631305446452 1.0 0.2292610471636748 23 P08670,P31749,P05067,Q8IXJ6 4 +Ion transmembrane transport 0.3527922373071334 2.5129261033203547 0.0119734412395993 1.0 0.2292610471636748 165 P21796,O75964,P06576,P00846,Q96ES6,Q9UHG3,Q9BQT8,P13073,P08183,Q13423,Q9Y619,P41440,O00400,Q8IWX8,P46934,Q14728,Q9UJS0,Q9C0H2,Q15043,P30825,P45880,Q9Y277,Q9HD20,P98194,Q8IYU8,Q96NB2,O43772,Q70HW3,Q13546,P0DP25,P53985,Q8NEW0,O75844,P33527,P05067 35 +Cellular response to amyloid beta 0.8431146310516165 2.5069417002071237 0.0121780796034733 1.0 0.2292610471636748 7 P09874,P33527 2 +Response to amyloid beta 0.8431146310516165 2.5069417002071237 0.0121780796034733 1.0 0.2292610471636748 7 P09874,P33527 2 +Macromolecule deacylation 0.4832170966187482 2.5036367493249294 0.0122924166790996 1.0 0.2306015622618112 42 Q8IXJ6,Q8N163,Q9ULX6,O95983,Q9UMR5,Q9NTG7,O75608,Q9NUJ1,Q96PK6,O43823,Q96EB6,Q92830,P50897 13 +Response to oxidative stress 0.3966921889028053 2.502864147728403 0.0123192821241702 1.0 0.2306015622618112 98 P09874,P00374,P30519,Q8IXJ6,Q9NR28,Q99720,Q15392,P31749,P05067,P46108,O95831,O43169,Q7Z2K6,P33527,Q15165,Q96IZ0,P09601 17 +Purine nucleoside metabolic process 0.7751804723736203 2.501732508902475 0.0123587261506439 1.0 0.2306845512934641 9 P55263,P00813,Q13126,P49902 4 +Inorganic anion transport 0.536356834405972 2.4966980273044723 0.0125355654752381 1.0 0.2317080934168745 30 P21796,P08183,Q9C0H2,P30536,Q9UHG3,P45880,O43681,P33527 8 +Fatty acid transmembrane transport 0.7908067026236297 2.48841245270322 0.0128314824806581 1.0 0.2323962764109034 8 O43772,P31749,P23786 3 +Ribonucleoside metabolic process 0.789558814900976 2.482410753420867 0.0130496752469582 1.0 0.2332689940970734 8 P55263,P00813,Q13126,P49902 4 +Purine ribonucleoside metabolic process 0.789558814900976 2.482410753420867 0.0130496752469582 1.0 0.2332689940970734 8 P55263,P00813,Q13126,P49902 4 +Protein processing 0.4594125013383682 2.4735530791303635 0.0133776930146491 1.0 0.2338080086830863 47 P67812,P09874,Q9NQH7,Q9HB09,P42892,Q5JRX3,Q15392,O75503,P42575,O75787,Q8TCT9,O75844,O75976,Q9H9S5,Q92896,Q10713 16 +Protein import into mitochondrial matrix 0.7668045124277458 2.460293882460885 0.0138823287484268 1.0 0.2419858839242981 9 Q99595 1 +Fat cell differentiation 0.5475495455035289 2.4409227250505565 0.0146497891497012 1.0 0.2494081243774226 27 P31751,Q8IXJ6,Q9BRK5,Q02252,Q96A49,P31749,Q9NZ08,Q8N4Q0 8 +Phosphatidylinositol 3 kinase signaling 0.6362380469102605 2.4203009131831204 0.0155076683716122 1.0 0.2562388487736111 17 O95630,Q8IXJ6,O00165,P22681,Q07021,P31749,P46934,Q10713 8 +Inositol lipid mediated signaling 0.5775502332907672 2.414769398668378 0.0157451745501397 1.0 0.2578871551424237 22 O95630,Q8IXJ6,O00165,P42356,P22681,Q07021,P46934,P31749,Q10713 9 +Rna splicing 0.3640252509101195 2.413222272198024 0.0158121734219971 1.0 0.2578871551424237 246 O75940,Q86V81,P98179,Q14011,O75400,Q92841,P38159,Q96PK6,P31942,Q96I25,P23246,P35637,P52272,P55081,Q92804,Q15233,P52597,O75312,P55795,P62312,Q15427,P31943,P51116,Q8N163,Q9ULX6,P19338,Q8IY67,O60828,P22626,Q9Y2W2,Q5T200,Q15459,O95391,P62310,P62995,Q96ST2,P49761,O75475,Q16637,Q6I9Y2,Q96E39,P78332,O75525,Q01130,Q92945,Q86UA1,P51114,Q15637,P52756,Q13242,Q9BWF3,P51991,O95400,Q07666,P61978,O60506,Q07955,Q9UHX1,O43390,Q13123,Q9UBB9,P98175,Q13595,Q14320,Q96PU8,Q07021,O60508,O75494,Q9P013,Q8WXF0,P38432,Q15007,Q9Y2W1,Q13148,Q8IXT5,Q8IWZ8,P67809,Q96EP5,O00566 79 +Collagen fibril organization 0.7563757959151808 2.40841849633147 0.0160218032681587 1.0 0.259474952524504 9 P13674,Q96AY3,Q92791 3 +Negative regulation of gliogenesis 0.8580662841309167 2.40440663330239 0.0161987435265416 1.0 0.2609621542698842 6 P30536,Q8IXJ6 2 +Protein hydroxylation 0.6499243591998257 2.3913921828155424 0.0167846129735071 1.0 0.2664624811930645 15 O15460,P13674,Q96AY3,Q92791 4 +Lipid localization 0.3979547111352509 2.3874504485164767 0.0169656896678371 1.0 0.2664624811930645 81 Q9BZF3,Q8WTV0,Q9H6V9,Q96EB6,P08183,Q9BQE5,P35610,P30536,O15118,Q9H4L5,P31749,P31751,Q14108,Q16739,P23786,Q9UHB6,Q9Y3D6,P35790,O43772,Q99720,Q9H2V7,P14174,P33527,Q7Z3C6 24 +Positive regulation of mrna splicing via spliceosome 0.6282595289646206 2.3701422143811164 0.0177812443164262 1.0 0.2693347558642128 17 P98179,Q14011,Q9Y2W1,Q96EP5,Q96E39,P62995,Q15427,P38159,Q13595 9 +Carboxylic acid transport 0.4905736066353353 2.360055435411335 0.0182722043506853 1.0 0.2705518077902598 35 Q9UJS0,Q9Y619,P41440,P30825,P53985,Q9BQT8,P33527,Q96NB2 8 +Vascular process in circulatory system 0.4865223418994254 2.347635368786341 0.018893006519542 1.0 0.2771034637161573 36 P08183,Q99808,P30825,P42892,Q9HB40,Q16625,P53985,P33527 8 +Peptidyl proline modification 0.4803962687916215 2.344672529532307 0.0190437974654493 1.0 0.2782252361415652 38 Q96AY3,O75718,O95302,Q9Y680,O15460,Q15257,Q9NWM8,P13674 8 +Mrna transport 0.3944935691797249 2.3360872050980066 0.0194866970176117 1.0 0.2810432966064258 80 Q07955,Q8TD16,P82979,Q9ULX6,P35658,O60318,Q96FV9,Q86V81,P22626,Q96MU7,Q9UPR3,P49790,Q08J23,Q16629,P49792,P09651,Q96PU8,Q96ST2,Q8NFH4,Q53F19,P37198,Q06787,Q99567,Q9BVL2,Q6I9Y2,O15504,Q9BZI7,Q9BTX1,Q92945,Q8N1F7,Q86U42,P51991,P57740,P41208,P52948 35 +Regulation of gliogenesis 0.6482041520215904 2.333879186770338 0.0196020488646604 1.0 0.2810432966064258 14 P30536,Q8IXJ6 2 +Positive regulation of nitric oxide synthase activity 0.8947972725979736 2.333525776575519 0.0196205670722349 1.0 0.2810432966064258 5 P31749,Q8WTV0,P00374 3 +Pigment metabolic process 0.5222234900525533 2.3295039829174575 0.0198323822487282 1.0 0.2828475468330536 29 P30519,P22830,P30536,Q9Y5Y0,P09601,P00813,P33527,O00264 8 +Peptidyl lysine hydroxylation 0.8393777980598145 2.3223228736312462 0.0202155567995385 1.0 0.2870696201555164 6 Q96AY3 1 +Organophosphate ester transport 0.5211912608853788 2.321005308364334 0.0202865573554558 1.0 0.2874583363765556 29 P08183,O00400,P41440,Q99808,Q14108,Q8WTV0,P33527 7 +Phosphatidylethanolamine metabolic process 0.9520834615942696 2.3063306442746865 0.0210921640952845 1.0 0.2913548621044656 4 P35790,Q9HBU6 2 +Organic cation transport 0.8857246556424055 2.295407384585818 0.0217097885506221 1.0 0.2955491668596056 5 Q99808,O43772 2 +Regulation of lipid transport 0.6061230438021371 2.2933373685484284 0.0218285894219438 1.0 0.2965537643323468 18 P31751,Q9BZF3,P30536,Q9Y3D6,P14174,Q96EB6,P31749 7 +Plasma lipoprotein particle clearance 0.649037757736806 2.256721498927878 0.0240254826023198 1.0 0.3153464240372221 12 P09601,Q8WTV0,Q92945 3 +Enzyme linked receptor protein signaling pathway 0.3327276770005342 2.2503098970306943 0.0244292801194399 1.0 0.3193740609265664 145 P53999,Q8NEM2,Q8IXJ6,Q99523,Q8TBX8,Q96EB6,Q92896,P16949,P25054,O00400,Q9UKG1,Q9P266,Q9H1E3,Q53EL6,P22681,P31749,P37198,P46934,P31751,Q9UQB8,Q04721,P08670,Q15043,Q9Y2U8,Q9UIQ6,Q6Y7W6,Q8N1F7,P09874,Q6ZWJ1,P46108,Q9HCD5,P05771 32 +Positive regulation of lipid biosynthetic process 0.6391363446710217 2.237721828541148 0.0252392008624919 1.0 0.3251841213255633 13 Q9NTG7,Q8WTV0 2 +Positive regulation of blood vessel endothelial cell migration 0.6452560150733738 2.234900248621237 0.0254238982432966 1.0 0.3254081491259213 12 P09601,Q9P266,P31749,P06576 4 +Embryonic digit morphogenesis 0.6751724912523089 2.234174640369279 0.0254715843556974 1.0 0.3254081491259213 11 P42892 1 +Regulation of nucleobase containing compound transport 0.645099138934895 2.2339939186159015 0.0254834732051867 1.0 0.3254081491259213 12 Q13546,P49790,Q08J23,Q9ULX6,Q96ST2,Q07666 6 +Positive regulation of monooxygenase activity 0.7827547017224665 2.230440469666553 0.025718215404495 1.0 0.3271376859077564 7 P31749,Q8WTV0,P00374 3 +Embryonic digestive tract development 0.9321906987962298 2.226967031267163 0.0259494772764998 1.0 0.3288098187978032 4 O94788 1 +Vascular transport 0.6134483279106223 2.2176481667647727 0.0265788309843202 1.0 0.3335026925821596 16 P08183,Q99808,P30825,P53985,P33527 5 +Regulation of dna binding 0.5130115508802591 2.207783916272937 0.0272593397764693 1.0 0.3363516662680831 28 Q00403,P09874,Q8IXJ6,P0DP25,P09601,O75844 6 +Neutral lipid biosynthetic process 0.7330778162603965 2.2063240031585023 0.0273613219065709 1.0 0.3369789720418613 8 Q8NCC3,Q8WTV0 2 +Positive regulation of lipid metabolic process 0.5361632979751998 2.203554562765395 0.0275556857366252 1.0 0.3372809115883842 23 Q9NTG7,Q8WTV0,P31749 3 +Facultative heterochromatin assembly 0.5713335893448402 2.2024298395522326 0.0276349600201779 1.0 0.3372809115883842 20 Q9UPP1,Q8IXJ6,O95983,Q5T5X7,Q9UK61,Q8NEY8 6 +Schwann cell development 0.6984684058221791 2.202135772384666 0.0276557192733826 1.0 0.3372809115883842 10 P31749,Q8IXJ6 2 +Phosphatidylcholine metabolic process 0.6395738790712494 2.202015148451437 0.0276642384372545 1.0 0.3372809115883842 12 Q8WTV0,Q8IY17,P35790 3 +Atp synthesis coupled proton transport 0.6391513602249863 2.1995651321576997 0.0278377633089506 1.0 0.3372809115883842 12 O75964,P00846 2 +Glial cell proliferation 0.8076039135734044 2.1810002791329617 0.0291833958363947 1.0 0.3489825683593555 6 P30536 1 +Protein adp ribosylation 0.6280748032591128 2.172416427867655 0.0298242670055772 1.0 0.3550398131680557 13 Q9NTG7,Q9UGN5,Q8IXJ6 3 +Terpenoid metabolic process 0.5654681306033341 2.1616711783053635 0.0306435307308614 1.0 0.362787096740817 20 P37268,Q9HB40,Q6NUM9,Q9BY49,O95749,O94788 6 +Regulation of centrosome cycle 0.5543393745149335 2.161352169787965 0.0306681458316337 1.0 0.362787096740817 21 Q9UPN4,Q9H0A0,Q9H444,P38398,Q96PK6,Q9HD42,Q96EB6,Q92830,P37198 9 +Negative regulation of lymphocyte apoptotic process 0.8025170869856358 2.158169649532649 0.0309146441805676 1.0 0.3637439116174291 6 P00813,Q99576,P14174 3 +Negative regulation of leukocyte apoptotic process 0.8025170869856358 2.158169649532649 0.0309146441805676 1.0 0.3637439116174291 6 P00813,Q99576,P14174 3 +Negative regulation of macroautophagy 0.6250916234796291 2.1547256372133865 0.0311833103692227 1.0 0.3655993452363141 13 Q9NRR5,Q9Y2S7,Q9H444,O15118,P09601,P31749 6 +Glycerolipid catabolic process 0.6873420393064023 2.143476723405892 0.0320748381842155 1.0 0.3747182780067307 10 Q8WTV0,Q8NCC3,Q8IY17 3 +Schwann cell differentiation 0.6577948173035236 2.1382241202637515 0.0324985576383751 1.0 0.378709484648883 11 P31749,Q8IXJ6 2 +Protein maturation 0.3808299244712624 2.134647923537792 0.0327897797530041 1.0 0.380266322095146 72 P67812,P09874,O75976,Q9BU89,Q9HB09,P42892,Q5JRX3,P49366,Q15392,O75503,Q5VZE5,Q8TCT9,O75844,Q9NRN7,Q92896,Q10713 16 +Mrna splice site selection 0.5505328832461597 2.134054781854712 0.0328382967479341 1.0 0.380266322095146 21 O75475,Q15637,Q07955,Q9UHX1,Q8WXF0,Q13242,Q15459,O95391,O75494,Q12874,Q86UA1 11 +Mitochondrial atp synthesis coupled proton transport 0.6562232484615582 2.129497533571087 0.0332131187286122 1.0 0.3825895792007445 11 O75964,P00846 2 +Regulation of mrna 3 end processing 0.5589674285272133 2.1163002099539856 0.0343192829099932 1.0 0.3898788880930089 20 Q5VTR2,O75150,P18615,Q8N684,P50750,Q16630,Q8N7H5,Q6PJT7,Q96MU7 9 +Positive regulation of b cell activation 0.653150851068212 2.112413708882059 0.0346509801815035 1.0 0.3908699854046887 11 P43246,O96028,Q12888,Q9NQT5,P14174,P00813,Q5RKV6,Q5UIP0 8 +Embryonic appendage morphogenesis 0.5879187088269314 2.112299439482942 0.0346607739107855 1.0 0.3908699854046887 17 P42892,O94788 2 +Sterol homeostasis 0.6227878881403912 2.104180715054844 0.0353626861120299 1.0 0.3948657879100416 12 Q5BJF2,P35610,Q9UHB6,Q8WTV0,Q96EB6,P34913 6 +Regulation of sterol transport 0.7123584192850789 2.102867041435641 0.0354773936018735 1.0 0.3948657879100416 8 Q9BZF3 1 +Low density lipoprotein particle clearance 0.6510889279867806 2.100931174771088 0.0356470083443563 1.0 0.395587357151657 11 P09601,Q8WTV0,Q92945 3 +Regulation of striated muscle cell differentiation 0.6159448249867789 2.100276377111024 0.0357045360614773 1.0 0.395587357151657 13 Q9BYT8,Q9UGN5,Q92830,Q8NEZ5 4 +Positive regulation of nuclear division 0.6016737811206344 2.096470892131859 0.0360404394102655 1.0 0.395587357151657 15 P37198,Q8IXJ6 2 +Regulation of glial cell proliferation 0.8385204542219487 2.0945361418732444 0.0362122470046206 1.0 0.395587357151657 5 P30536 1 +Microtubule organizing center organization 0.4163726776923198 2.0941758810005147 0.0362443154818492 1.0 0.395587357151657 52 Q9UPN4,Q9H0A0,Q96CS2,Q9H444,Q9C0F1,P38398,Q15154,O43379,P53985,Q9H6D7,Q96PK6,P41208,Q08379,Q9HD42,Q96EB6,Q92830,P37198 17 +Negative regulation of cellular catabolic process 0.3676327855929506 2.0939697535578254 0.0362626747184096 1.0 0.395587357151657 100 O60506,Q9Y2W1,Q9Y2S7,P46379,Q8IXJ6,Q8N163,Q9H814,Q13148,P98175,Q14011,Q99729,Q13151,Q08J23,P30536,Q9H444,O15118,P31749,Q96HY6,Q9UL15,Q9NRR5,P67809,P35637,P09601,Q92804,O43765,Q96JB5,Q92530,O95453,Q08379,Q9H2J4 30 +Regulation of glycoprotein metabolic process 0.6203657671705549 2.08997960352288 0.0366196319486229 1.0 0.3978158841686415 12 Q9NY61,P35610,O14734,Q08379,Q9NQX7,Q96IZ0 6 +Xenobiotic metabolic process 0.6141679649909123 2.0896629606410277 0.0366480864608234 1.0 0.3978158841686415 13 O43169,P07099 2 +Glycerophospholipid catabolic process 0.7525490626161668 2.088778226816981 0.036727691249353 1.0 0.3980242724374789 7 Q8WTV0,Q8NCC3,Q8IY17 3 +Positive regulation of adaptive immune response 0.5909021710857608 2.075501181786098 0.0379401094488687 1.0 0.4034200837352924 16 P43246,O96028,P00813,Q9NUQ9,Q12888,P04439,Q96EB6,Q5RKV6,Q5UIP0 9 +Cytochrome complex assembly 0.6115334934430101 2.0739054103444063 0.0380880964848795 1.0 0.4041263570674256 13 Q69YU5,P53701,Q6DKK2,Q9Y2R0 4 +Modulation of excitatory postsynaptic potential 0.8327299175888725 2.0696050500138976 0.0384893447750569 1.0 0.4047092303436001 5 Q9UQB8 1 +Positive regulation of mrna metabolic process 0.375578709016269 2.0636296625762274 0.0390528429432361 1.0 0.4071506046724418 71 O60506,P98179,Q9Y2W1,Q14011,P67809,Q9Y5A9,Q96E39,P62995,Q8N7H5,P38159,Q13148,Q6Y7W6,Q969T7,Q92945,Q13595 15 +Protein peptidyl prolyl isomerization 0.4902398904079621 2.062786146565686 0.0391329508209763 1.0 0.4073412527004946 29 Q96AY3,O95302,Q9Y680,Q15257,Q9NWM8 5 +Appendage morphogenesis 0.5705610131195915 2.0587545384802985 0.0395177587206516 1.0 0.4094064657395815 18 P42892,O94788 2 +Organic hydroxy compound transport 0.4784259761293278 2.0565830686980244 0.0397263482541627 1.0 0.4109213636525565 31 Q9BZF3,P35610,P30536,P53985,Q9UHB6,Q8WTV0,Q9H4L5,Q96EB6,Q14728 9 +Response to light stimulus 0.3776746958939099 2.0537715147220172 0.0399978111549861 1.0 0.4117899651565682 67 P31751,P09874,Q14011,Q9BRK5,P22830,Q8N163,Q96RU2,P31749,P05067,P46934 10 +Membrane lipid biosynthetic process 0.4990346074428295 2.0518586265905694 0.040183403721768 1.0 0.4125284914959156 27 Q9NTG7,Q96G23,Q06136,Q8NBX0 4 +Cellular response to biotic stimulus 0.4374473981609382 2.046786423648032 0.0406790592465797 1.0 0.4162023623846492 42 Q04721,Q8IXJ6,P08670,P30536,Q53EL6,Q96JM3,Q8WTV0,O43823,P14174,O75844,P31749 11 +Regulation of lymphocyte apoptotic process 0.6684240010642598 2.0428849597733088 0.0410638275239727 1.0 0.4171028071027695 10 P00813,Q99576,P14174 3 +Regulation of fatty acid transport 0.7742555122414965 2.0303042464002 0.0423256228559627 1.0 0.4247406351172887 6 P31751,Q9Y3D6,P31749 3 +Transition metal ion transport 0.5832646744582394 2.026876926030039 0.0426750008069858 1.0 0.4260387580564085 16 Q8NEW0,Q07960,O15173,Q15043,Q9HD20,O75027,P98194,Q9Y5Y0,Q8N4V1 9 +Tetrapyrrole catabolic process 0.8815214556072145 2.0219108462172777 0.0431855630550543 1.0 0.4297458376315436 4 P33527,P30519 2 +Epoxide metabolic process 0.9922302158273382 2.021365021916085 0.0432419927682066 1.0 0.4297458376315436 2 P07099 1 +Positive regulation of leukocyte proliferation 0.5736415442364194 2.019369877893187 0.0434487899181514 1.0 0.43071274733179 17 P30825,P49366,Q9HCL2,P04439,P14174,P00813 6 +Membrane protein proteolysis 0.6076527882952864 2.015097806676859 0.0438944020192386 1.0 0.4329643935700053 12 O43847,Q8TCT8,P38159,Q9Y5X1,Q8TCT9,Q16740,Q9NZ08 7 +Regulation of peptidyl threonine phosphorylation 0.6355035059575852 2.0136900788928616 0.0440420822900127 1.0 0.4337717192958054 11 P05067,Q8IXJ6 2 +Steroid metabolic process 0.3715060334671984 2.007890878149939 0.0446548887264328 1.0 0.437843841991765 72 P37268,O75845,Q16850,Q9BQE5,P48449,Q9BZF3,P35610,P30536,Q15392,O14734,P05067,Q9UHB6,Q8WTV0,Q9H4L5,Q96EB6,P34913 16 +Regulation of rna export from nucleus 0.6336749835380072 2.0034032242943938 0.0451340256714267 1.0 0.440310813604777 11 P49790,Q08J23,Q9ULX6,Q96ST2,Q07666 5 +Glycosyl compound catabolic process 0.6601924840412554 1.99878383919992 0.0456317470979223 1.0 0.4415258776478865 10 P00813,Q13126,Q9NUJ1 3 +Centriole assembly 0.6046590470874401 1.997380594076994 0.0457838542771562 1.0 0.4415258776478865 12 Q9C0F1,P38398,P41208,Q96PK6,Q92830,P37198 6 +Ion transport 0.3382493030522819 1.9962248105574656 0.0459094580211534 1.0 0.4415258776478865 218 P21796,O75964,P06576,P00846,Q96ES6,Q9UHG3,Q9BQT8,P13073,P08183,Q13423,Q9Y619,P41440,O00400,Q99808,P30536,O43681,Q9Y5Y0,P31749,P46934,Q14728,Q9UJS0,Q9C0H2,O15173,Q15043,P30825,P45880,Q9HD20,Q8IYU8,Q96NB2,O43772,Q70HW3,P0DP25,P53985,P14174,Q8NEW0,O75844,P33527,P05067,P05771 39 +Amyloid precursor protein biosynthetic process 0.8134949731515876 1.9863444813779592 0.046995086721731 1.0 0.444379285039242 5 Q9NQX7,Q96IZ0,Q9NY61 3 +Adenosine metabolic process 0.9835971223021585 1.9860803558936928 0.0470244021247838 1.0 0.444379285039242 2 P49902 1 +Vitamin transport 0.6735636522142547 1.985410398974688 0.0470988299421077 1.0 0.444379285039242 9 P33527,Q8WTV0 2 +Sterol transport 0.5034318505987968 1.9821975723000445 0.0474571322966832 1.0 0.4451615318699115 24 Q9BZF3,P35610,P30536,Q9UHB6,Q8WTV0,Q9H4L5,Q96EB6 7 +Nucleolar chromatin organization 0.6884102163994419 1.9818537879403573 0.0474956073614429 1.0 0.4451615318699115 8 Q9UPP1,Q8IXJ6 2 +Regulation of b cell mediated immunity 0.6260736890525842 1.9605254884263572 0.049934401838694 1.0 0.4569691301599373 11 P43246,O96028,Q96QE3,Q96FZ2,Q12888,Q96FV9,Q9NQT5,Q5RKV6,Q5UIP0 9 +Regulation of isotype switching 0.6260736890525842 1.9605254884263572 0.049934401838694 1.0 0.4569691301599373 11 P43246,O96028,Q96QE3,Q96FZ2,Q12888,Q96FV9,Q9NQT5,Q5RKV6,Q5UIP0 9 +Nucleoside metabolic process 0.5366044028592263 1.9586516886694876 0.0501535918419429 1.0 0.4579197290878831 20 Q13126,P31939,P49902,P55263,P00813 5 +Response to oxygen levels 0.3676437901244658 1.9548048759053784 0.050606105450625 1.0 0.460874658432208 73 P55786,P30519,Q8IXJ6,Q99808,P00846,O95831,P00813,P31749 8 +Establishment of protein localization to organelle 0.33002187787875 1.954509816964996 0.0506409550318589 1.0 0.460874658432208 190 Q99595,O60830,P46379,Q99816,Q99523,Q5JRX3,P35658,Q9NS69,O00189,Q9P0J0,Q13501,Q13148,O95831,Q10713,O14925,P55786,Q9H9H4,Q15070,P02545,O95429,P49790,O00165,Q9UKG1,P30536,Q9H444,P49792,O43681,O43464,P31749,Q9P275,P37198,Q9UHB9,P46934,Q6UWE0,Q92973,Q99797,Q99567,Q9BVL2,O75381,Q14108,Q7Z4Q2,Q3ZCQ8,Q14978,P52292,Q9Y3D6,Q8N4H5,O43615,Q8N1F7,Q9UII2,O75312,O43765,Q9Y2T2,P0DP25,P56589,Q96EP0,O14737,P57740,Q9H1Z9,Q9Y512,P40855,Q15629,P52948 62 +Mrna processing 0.3451188029452681 1.9524695873663171 0.0508824782854029 1.0 0.461797037772066 288 O75150,O75940,P18615,Q86V81,Q5VTR2,P98179,Q14011,O75400,Q92841,P38159,Q96PK6,P31942,Q96I25,P23246,P52272,P55081,Q6PJT7,Q15233,P52597,O75312,Q8N684,P62312,Q15427,P31943,P05067,P51116,Q8N163,Q9ULX6,P50750,P33240,P19338,Q8IY67,O60828,P22626,Q9Y2W2,Q5T200,Q15459,O95391,P62310,P62995,Q6P2P2,Q96ST2,O75475,Q16637,Q6UN15,Q6I9Y2,Q96E39,P78332,O75525,Q01130,Q92945,Q86UA1,P51114,Q15637,P52756,Q13242,Q9BXP5,Q9BWF3,Q96DF8,P51991,O95400,Q07666,Q15424,P61978,P52948,O60506,Q07955,Q9UHX1,O43390,Q13123,Q9UBB9,P98175,Q13595,Q14320,P09651,Q96PU8,O75934,Q07021,Q53F19,Q9Y3B4,Q96RS0,Q99590,Q15020,Q06787,Q9H0D6,O60508,O75494,Q12874,Q9P013,Q86U42,Q8WXF0,Q12849,Q8WWY3,Q92917,P38432,O43290,Q15007,Q9Y2W1,Q14562,P07910,Q96FV9,Q13148,Q96MU7,Q6NZY4,Q13573,Q13151,Q8IWZ8,P67809,Q8N7H5,Q96EP5 110 +Negative regulation of microtubule polymerization or depolymerization 0.571210181434058 1.9496548776219065 0.0512172678205977 1.0 0.4641961178403282 16 P16949,Q9Y3E1,P25054 3 +Nucleus organization 0.3668712350919179 1.944419030817814 0.0518449407722438 1.0 0.4659799811914826 72 Q8NC51,Q8IXJ6,Q9ULX6,Q86XL3,Q13148,Q96EB6,Q9Y3E7,P20700,P50402,P02545,P49790,Q9H444,P12270,Q9HD42,Q9P275,Q5T5X7,Q14978,Q9Y2U8,O43159,Q9NZZ3,Q9BTX1,Q8N1F7,Q9BPY3,Q15637,O75312,Q9UPP1,Q9UNZ2,Q9NQC3,P57740,Q9UH99,O75844,P52948,P05771 33 +Organophosphate catabolic process 0.4361281201311889 1.9439545139921983 0.0519009364973268 1.0 0.4659799811914826 39 Q8IY17,P49902,Q9BQG2,Q8WTV0,Q8NHP8,Q9Y3Z3,Q8NCC3,P00813,Q9H773,Q10713 10 +Negative regulation of cellular response to insulin stimulus 0.7216301338996244 1.9415359700382704 0.0521933008337449 1.0 0.4659799811914826 7 Q9HCD5,Q8TBX8,P05771 3 +Peroxisome organization 0.6495421043608706 1.9414292512847424 0.0522062331354173 1.0 0.4659799811914826 10 O75381,P56589,P40855,O14734 4 +Centrosome duplication 0.4855113882423183 1.940738044414904 0.0522900592840431 1.0 0.4659799811914826 27 Q9UPN4,Q9H0A0,Q9H444,Q9C0F1,P38398,Q96PK6,P41208,Q9HD42,Q96EB6,Q92830,P37198 11 +Cellular response to zinc ion 0.9720863309352517 1.938906688421372 0.0525127013904787 1.0 0.4659799811914826 2 P30536 1 +Protein auto adp ribosylation 0.9720863309352517 1.938906688421372 0.0525127013904787 1.0 0.4659799811914826 2 Q9UGN5 1 +Cellular response to oxygen levels 0.4267498739471982 1.9372169989289376 0.0527188231745692 1.0 0.4659799811914826 42 Q15118,P55786,Q8IXJ6,Q99808,P22681,O95831,Q96EB6,P31749,P09601 9 +Signal peptide processing 0.8010922181300262 1.9323017802936424 0.0533222688229977 1.0 0.4659799811914826 5 P67812,O75503 2 +Gmp biosynthetic process 0.59358474504513 1.9315691367628496 0.0534127082822828 1.0 0.4659799811914826 12 P55263,P31939 2 +Neuron projection regeneration 0.6626641395487018 1.92829372762971 0.0538186015611956 1.0 0.4659799811914826 9 P30536,P00374 2 +Terpenoid biosynthetic process 0.7508584226627567 1.923159991724114 0.0544599600543964 1.0 0.4702970862364591 6 O95749,O94788 2 +Regulation of blood pressure 0.5589046132923995 1.9225533040339955 0.0545361732020672 1.0 0.4703388026550016 17 P42892,Q9HB40,Q9UIQ6,P42785,Q9NZ08 5 +Regulation of centriole replication 0.7172392044871264 1.9204464698698072 0.0548015285706409 1.0 0.4713933051592075 7 Q96PK6,Q92830,P37198 3 +Response to nerve growth factor 0.5796439412074739 1.9179626725447705 0.0551157443959646 1.0 0.4734780180247865 14 Q99523,P05067,P46108,P31749,Q92830 5 +Lipid translocation 0.7162279369321033 1.9155831942516977 0.0554181703831682 1.0 0.4742212008502536 7 P08183,P33527 2 +Regulation of membrane lipid distribution 0.6750079512627182 1.9134737206442851 0.0556874346372406 1.0 0.474806848256083 8 P08183,P33527 2 +Farnesyl diphosphate metabolic process 0.854546286560047 1.9111025702404083 0.055991400929034 1.0 0.474806848256083 4 P37268 1 +Sphingolipid translocation 0.964892086330935 1.9093519695959649 0.056216702339467 1.0 0.474806848256083 2 P08183 1 +Xenobiotic transport across blood brain barrier 0.964892086330935 1.9093519695959649 0.056216702339467 1.0 0.474806848256083 2 P08183 1 +Regulation of mrna polyadenylation 0.5714248244332871 1.906880404142584 0.0565360762800826 1.0 0.474806848256083 15 Q5VTR2,O75150,P18615,Q8N684,P50750,Q16630,Q6PJT7,Q96MU7 8 +Xenobiotic transport 0.7136635776714939 1.9032406281525192 0.0570091540205492 1.0 0.474806848256083 7 P08183,P41440,P11166,Q5T3U5,P33527 5 +Negative regulation of response to cytokine stimulus 0.6155466105604177 1.900842419833872 0.0573226559450545 1.0 0.474806848256083 11 Q14166,Q9Y5A9,Q9UJ41,Q01804,Q7Z739,Q9Y3Z3 6 +Microtubule anchoring 0.6155438040522978 1.9008264622772293 0.057324746762996 1.0 0.474806848256083 11 Q9UIS9,Q8IWJ2,O75381,Q8TD16,Q15154,O95684 6 +Negative regulation of mrna 3 end processing 0.7130350226646942 1.900213062472646 0.0574051647554441 1.0 0.474806848256083 7 Q5VTR2,Q6PJT7,O75150,P18615 4 +Tetrapyrrole biosynthetic process 0.5823971448273884 1.8979460098884695 0.057703194563605 1.0 0.474806848256083 13 P36551,P22830,P30536,Q9Y5Y0,O00264 5 +Membrane lipid metabolic process 0.4228435919307271 1.896954021784915 0.0578340066171814 1.0 0.474806848256083 42 Q96G23,Q8NBX0,Q16739,Q9NTG7,Q8NCC3,Q06136 6 +Lipoprotein localization 0.7450370398061155 1.8963250715823945 0.0579170729923825 1.0 0.474806848256083 6 A6NIH7,P05771 2 +Oocyte maturation 0.7115522494874368 1.8930674701252896 0.0583488974974006 1.0 0.474806848256083 7 Q9Y5A9,Q8IXJ6 2 +Regulation of adaptive immune response 0.5173469774388966 1.8929468884117464 0.0583649328881654 1.0 0.474806848256083 21 P43246,O96028,P00813,Q9NUQ9,Q12888,P04439,Q96FV9,Q96EB6,Q5RKV6,Q5UIP0 10 +Response to food 0.7111717741460993 1.8912331387480057 0.058593229494388 1.0 0.474806848256083 7 P31749,Q9UMX5,P53985 3 +Bile acid biosynthetic process 0.6554519523626217 1.8903224632214828 0.0587148462862467 1.0 0.474806848256083 9 Q9H4L5,O14734,Q9BZF3 3 +Appendage development 0.5063080728137428 1.8891999751114403 0.0588650380761559 1.0 0.474806848256083 22 Q9Y5Y0,P42892,O94788 3 +Response to interleukin 7 0.6550632444778108 1.8882720047487345 0.0589894436164177 1.0 0.474806848256083 9 P31939,P06576,P51858 3 +Response to manganese ion 0.7908404499618181 1.88742612762708 0.0591030336509472 1.0 0.474806848256083 5 P30536 1 +Peroxisomal transport 0.8485981819814091 1.8865229671429289 0.0592245164309161 1.0 0.474806848256083 4 O75381,P56589 2 +Regulation of fat cell differentiation 0.5805115752138105 1.886454326371839 0.0592337576667931 1.0 0.474806848256083 13 Q8IXJ6,Q99523,Q96A49,P31749,Q8N4Q0 5 +Regulation of plasma lipoprotein particle levels 0.5743656032621477 1.885207969874004 0.0594017652347007 1.0 0.4755750074501133 14 P09601,Q8WTV0,Q92945 3 +Endothelial cell proliferation 0.5255793819504153 1.8800575201272984 0.0601002390930551 1.0 0.4769911434145942 20 Q9UII2,Q9P266,Q8WTV0,P09601,Q96EB6,P31749,O94788 7 +Regulation of lipoprotein particle clearance 0.7414485685450201 1.879748871589048 0.0601423115735668 1.0 0.4769911434145942 6 Q92945 1 +Cellular response to estradiol stimulus 0.7409093249400995 1.8772556977115236 0.0604830570219929 1.0 0.4769911434145942 6 O95831 1 +Negative regulation of peptidyl threonine phosphorylation 0.8462651099811631 1.876867912272674 0.0605361997006865 1.0 0.4769911434145942 4 Q8IXJ6 1 +Regulation of myelination 0.578917302406293 1.8767283045776688 0.0605553412128849 1.0 0.4769911434145942 13 O75312,P31749,Q15058,Q8IXJ6 4 +Phosphatidylcholine catabolic process 0.9562589928057548 1.87381713016538 0.0609556345057695 1.0 0.4781388997125187 2 Q8WTV0 1 +Sphingolipid metabolic process 0.4460062845434366 1.869565164301876 0.061544226579153 1.0 0.4789166538923151 33 O15269,Q96G23,Q99805,Q16739,P27544,Q9NTG7,P16278,P06865,Q8NCC3,Q06136,P50897 11 +Histone h2b ubiquitination 0.705419324618963 1.8634604348017163 0.0623975141048585 1.0 0.481144765898323 7 Q5VTR2,O75150,Q8N7H5 3 +Ceramide biosynthetic process 0.5703997000653787 1.8605317290190109 0.0628103337143108 1.0 0.481144765898323 14 Q9NTG7,Q96G23,Q16739 3 +Ornithine transport 0.9528057553956832 1.8595827825852136 0.062944577117556 1.0 0.481144765898323 2 P30825 1 +Nitrogen compound transport 0.2682344603487553 1.8569998080343637 0.0633111813940825 1.0 0.481144765898323 620 Q99595,O60830,P46379,Q32P28,Q14C86,Q9NS69,O75608,O95831,A6NIH7,Q86V81,Q12768,P55786,P08183,Q15070,P02545,O95429,Q99808,P30536,Q9UKG1,Q9P253,P46934,Q9UHB9,Q6UWE0,P24390,O15260,P53367,Q9BVL2,P30825,Q7Z4Q2,Q3ZCQ8,Q13596,O95235,O15504,Q9H2J7,O43823,O43615,Q96NB2,O43772,O75312,P43307,P57740,Q15629,P33527,P82979,P05771,Q9UPN4,Q9ULX6,P35658,O60725,O60318,Q9H814,P22626,O14925,Q4J6C6,Q9Y5X2,Q9UPR3,Q9Y619,Q8N183,O00165,O95391,O43681,Q96ST2,Q9Y5Y0,Q9HD42,P31749,P37198,P31751,Q6NUQ1,Q9Y679,Q96ED9,Q99797,O15173,Q6I9Y2,O75381,Q9UJ41,Q14978,A0AVF1,P52292,Q9HD20,Q9NVZ3,Q9NQG6,Q9BZI7,O95721,Q13432,Q92945,Q15904,P18031,Q9Y2T2,P56589,Q96EP0,P53985,P51991,Q6P4A7,P04035,P40855,Q07666,Q9Y282,P50897,P52948,Q07955,Q99816,Q8TD16,O60499,O00189,Q9NV70,Q10713,O00400,P41440,Q08J23,P49790,Q9H444,P49792,Q96PU8,P09651,O75746,O43464,Q96C92,O15027,O00330,Q53F19,Q9Y5X1,Q9P275,P00367,Q92973,Q15717,Q9UJS0,Q07960,Q06787,Q9UNK0,Q9Y4P1,Q14108,Q9H2D1,Q96KC8,Q8N6H7,Q9Y3D6,Q8N4H5,Q9BSK2,Q8N1F7,Q16850,O43765,O00233,Q6ZWJ1,P41208,Q96PC5,Q9P2W9,P49321,Q99523,Q5JRX3,Q15154,Q9P0J0,Q13501,Q13148,Q9H9H4,Q6WKZ4,Q8N6T3,Q8NFH4,Q8TCT9,Q15363,P67809,Q99567,Q9Y277,P98194,Q9BTX1,Q9UII2,Q13546,Q7Z7E8,Q9H6Z4,O14737,Q9Y512,Q08379 170 +Macrophage differentiation 0.7039735610845556 1.8564688097404405 0.0633867647680168 1.0 0.481144765898323 7 P09874,P05067,Q13546 3 +Regulation of mrna catabolic process 0.3589884157088669 1.8559896746433024 0.0634550298075031 1.0 0.481144765898323 85 P51116,O60506,Q9Y2W1,Q8NC51,Q9Y5A9,Q13464,P07910,Q9P2K5,Q13148,P98175,Q969T7,Q53R41,Q14011,Q99729,Q13151,Q13868,Q7Z739,P31749,Q15717,Q86U44,P67809,Q06787,P08670,Q14671,P35637,P52272,Q14103,Q6Y7W6,Q6PJT7,Q92804,Q92945,P51114,O95453,A2RRP1 34 +Mitochondrial respiratory chain complex assembly 0.4126025472604153 1.8559794423330027 0.0634564883238189 1.0 0.481144765898323 44 Q9H061,O75489,O43676,O95169,Q8N183,Q69YU5,Q9P0J0,Q9Y512,Q6DKK2,Q9Y2R0,O95831,O96000,Q9BSK2 13 +Embryonic organ development 0.3885462480404181 1.853995999962549 0.0637397322651163 1.0 0.4827368918331625 56 Q15363,Q04721,Q9H6E4,P42892,O60508,O95983,P62995,Q9Y5Y0,Q8IZL8,P00813,P31749,O94788 12 +Regulation of reproductive process 0.5012347280636376 1.8507429367461092 0.0642065438675212 1.0 0.4850092037209222 22 Q8IXJ6,Q96B01,Q9Y5A9,Q7Z739,P33981,Q07021,Q13162,Q9NVM9,P00813 9 +Glycosyl compound metabolic process 0.4653353012322424 1.8503675610814807 0.0642605911137297 1.0 0.4850092037209222 29 Q13126,P31939,P49902,Q9NUJ1,P55263,P00813 6 +Regulation of oxidoreductase activity 0.5301416074524394 1.8457717040605697 0.0649253607830058 1.0 0.4877915646513401 19 Q9NTG7,P31749,Q8WTV0,P00374 4 +Negative regulation of b cell apoptotic process 0.8365777045782221 1.836695131353092 0.0662549144123523 1.0 0.4915065464610869 4 P00813 1 +Nuclear membrane organization 0.4847532910614382 1.8345840468474777 0.0665673442157968 1.0 0.4915065464610869 24 Q8IXJ6,Q9ULX6,Q9H444,Q86XL3,Q9HD42,P05771 6 +Execution phase of apoptosis 0.5283828623995593 1.8334766228896424 0.0667317219393588 1.0 0.4915065464610869 19 O95831,Q8IXJ6 2 +Modified amino acid transport 0.6989654041463832 1.832214267922728 0.066919503967894 1.0 0.4915065464610869 7 O43772,P33527 2 +Regulation of nitric oxide synthase activity 0.6444448775383332 1.832105020470064 0.0669357755423125 1.0 0.4915065464610869 9 P31749,Q8WTV0,P00374 3 +Positive regulation of glycogen metabolic process 0.9450359712230216 1.8275145046965624 0.0676224473714373 1.0 0.4927006694223141 2 P31749 1 +Mammary gland epithelial cell differentiation 0.9450359712230216 1.8275145046965624 0.0676224473714373 1.0 0.4927006694223141 2 P31749 1 +Regulation of superoxide metabolic process 0.7770711649187063 1.8268684122967032 0.0677195566475641 1.0 0.4927006694223141 5 P00374 1 +Positive regulation of chemokine production 0.6977668823633253 1.826401724488396 0.0677897723074494 1.0 0.4927006694223141 7 P09601,P05067 2 +Regulation of b cell activation 0.5264323543186331 1.8198255831525176 0.0687855704473996 1.0 0.4975061730822351 19 P43246,O96028,Q12888,Q96FV9,P14174,P00813,Q5RKV6,Q96IZ0,P07948,Q5UIP0 10 +Regulation of amyloid fibril formation 0.7282874642551427 1.818733236315484 0.0689521384581606 1.0 0.4981640792772152 6 P05067 1 +Triglyceride biosynthetic process 0.7279042873457561 1.8169516845560376 0.069224511712749 1.0 0.4988458551584013 6 Q8WTV0 1 +Ribonucleoprotein complex localization 0.6955004012113122 1.815401354404568 0.0694622531038207 1.0 0.4988458551584013 7 Q08J23,Q9ULX6,Q8WWY3,Q9BVS4,Q96ST2 5 +Cation transport 0.3152477835314409 1.8143804737930491 0.0696191698068124 1.0 0.4991520237835555 162 P21796,O75964,P06576,P00846,Q96ES6,P13073,Q13423,Q9Y619,O00400,Q99808,P30536,Q9Y5Y0,P31749,P46934,O15173,Q15043,P30825,Q9HD20,Q8IYU8,Q96NB2,O43772,Q70HW3,P0DP25,Q8NEW0,O75844,P05067,P05771 27 +Negative regulation of leukocyte migration 0.6408883736183459 1.8132267485655569 0.0697968558727508 1.0 0.4995941517289627 9 P09601,P00813,P31749 3 +Regulation of b cell apoptotic process 0.7264021544482563 1.8099648751961923 0.0703012343477169 1.0 0.5007727925590346 6 P00813 1 +Positive regulation of mitochondrial translation 0.6246286043376326 1.8060031478557008 0.0709178478692262 1.0 0.5031557120984852 10 Q07021,Q567V2,Q9Y2R0 3 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.541175811162048 1.8049179248368643 0.0710875264042154 1.0 0.5032823575208897 17 Q15118,P09874,P23246,Q9NR28,Q96EB6,P31749,Q9UL15 7 +Sphingolipid biosynthetic process 0.5147476834599498 1.8023013946280444 0.0714979992423567 1.0 0.5038506064255496 20 Q16739,P27544,Q9NTG7,Q96G23,Q06136 5 +Response to radiation 0.3483762083500877 1.7991767219438213 0.0719907304449383 1.0 0.5040847522206029 100 P31751,P09874,Q14011,P16104,Q9BRK5,P22830,Q8N163,Q96RU2,P12956,Q70UQ0,O75844,P31749,P05067,P46934 14 +Chemokine production 0.6524565627405566 1.7973873124393829 0.0722741535344968 1.0 0.5040847522206029 8 Q7Z434,P05067,P14174,P09601 4 +Export across plasma membrane 0.6226440255069565 1.7951415185410131 0.0726311552393674 1.0 0.5040847522206029 10 P08183,P33527 2 +Response to molecule of bacterial origin 0.4035479867611019 1.7942775614265811 0.0727688777242723 1.0 0.5040847522206029 45 P51812,Q13151,Q8IXJ6,P08670,P30536,Q53EL6,Q96JM3,Q8WTV0,O43823,P14174,P31749 11 +Positive regulation of isotype switching 0.6371139416051799 1.7931562184097125 0.0729479484764061 1.0 0.5040847522206029 9 P43246,O96028,Q96FZ2,Q12888,Q9NQT5,Q5RKV6,Q5UIP0 7 +Positive regulation of b cell mediated immunity 0.6371139416051799 1.7931562184097125 0.0729479484764061 1.0 0.5040847522206029 9 P43246,O96028,Q96FZ2,Q12888,Q9NQT5,Q5RKV6,Q5UIP0 7 +Positive regulation of actin cytoskeleton reorganization 0.7688586558162087 1.7905987236219405 0.0733577120215278 1.0 0.5040847522206029 5 Q9UQB8 1 +Digestive system development 0.5531361117968348 1.7905799389673056 0.0733607286622373 1.0 0.5040847522206029 15 O94788 1 +Phosphatidylethanolamine biosynthetic process 0.9678248558113915 1.7891499091914007 0.0735906761933367 1.0 0.5045670816211192 3 Q9HBU6 1 +Long chain fatty acid metabolic process 0.4813728082244141 1.7802595018092977 0.0750335015926344 1.0 0.5097271114559427 23 P07099,Q9H7Z7,P23786,O14734 4 +Rna polyadenylation 0.4305471882980392 1.7797501125364603 0.0751168652638822 1.0 0.5097271114559427 34 Q5VTR2,O75150,Q6UN15,P18615,Q8N684,P50750,Q8N7H5,Q6PJT7,P05067 9 +Fatty acid transport 0.528113575074656 1.7715156313012284 0.0764749956642982 1.0 0.5107911940195756 18 P31751,O43772,P23786,Q9Y3D6,P31749 5 +Membrane protein ectodomain proteolysis 0.6181816047085926 1.7706801077057794 0.0766139122245013 1.0 0.5107911940195756 10 O43847,Q8TCT8,P38159,Q9Y5X1,Q8TCT9,Q9NZ08 6 +External encapsulating structure organization 0.4557843329270531 1.7678631084775025 0.077083791515502 1.0 0.5112482339923445 29 Q96AY3,O75718,Q92791,P13674,P05067 5 +Purine nucleoside biosynthetic process 0.7172568626016076 1.7673339839836832 0.0771723116561462 1.0 0.5112482339923445 6 P55263,P00813 2 +Autophagy of mitochondrion 0.4291251944741908 1.7662171467297707 0.0773594254392526 1.0 0.5112482339923445 34 Q9UII2,P21796,Q9Y4P1,O00165,P30536,P27544,Q9Y3D6,Q13501,Q7KZI7 9 +Homologous chromosome pairing at meiosis 0.6319671187063239 1.7657299300585214 0.0774411689423217 1.0 0.5112482339923445 9 Q92791,Q9BTX1,Q9BXW9 3 +Regulation of protein acetylation 0.4683134607507889 1.763391917804472 0.0778344119987564 1.0 0.5112482339923445 26 O75844,Q03164,Q9NPI1,P38398,Q9NYB0,Q96EB6,Q92830,Q01105 8 +Regulation of phosphatidylinositol 3 kinase signaling 0.5655784287767214 1.763279387094859 0.0778533800963818 1.0 0.5112482339923445 12 O95630,O00165,P22681,P46934,Q10713 5 +Protein import into peroxisome membrane 0.9294964028776976 1.7632177137042702 0.0778637773166601 1.0 0.5112482339923445 2 P56589 1 +Positive regulation of b cell proliferation 0.8179231564352687 1.7589722048924985 0.0785822297141756 1.0 0.5117078038718662 4 P00813 1 +B cell activation 0.4035079595444252 1.7589428463068313 0.0785872166810766 1.0 0.5117078038718662 44 O96028,Q9UQ84,P55327,P14174,P00813,Q5RKV6,Q96IZ0,P05771 8 +Regulation of leukocyte proliferation 0.4627017882997118 1.7508178535263688 0.0799772902680058 1.0 0.5171446178369875 27 P30825,P49366,Q9HCL2,P04439,P14174,P00813,Q96IZ0 7 +Positive regulation of dna binding 0.5241596687971896 1.7443835815043658 0.0810922259996755 1.0 0.5197633045835238 18 Q00403,P09874,Q8IXJ6,P0DP25 4 +Cell death in response to oxidative stress 0.4654521019797794 1.739763550844893 0.0819005451126602 1.0 0.5219576624760454 26 Q15118,P09874,P23246,Q13546,Q9NR28,Q99720,Q96EB6,P31749,Q96IZ0,Q9UL15 10 +Membrane biogenesis 0.4569394978064257 1.738539154157104 0.082115857203795 1.0 0.5219576624760454 28 P41440,Q8IXJ6,Q16739,Q86XL3,Q9HD42 5 +Positive regulation of endothelial cell migration 0.4725684634026931 1.737273390212294 0.0823389261288343 1.0 0.5219576624760454 24 P09601,Q8WTV0,P31749,P06576 4 +Lipopolysaccharide mediated signaling pathway 0.6117541465575815 1.7353548009938935 0.0826779806927495 1.0 0.5219576624760454 10 Q8WTV0,P31749 2 +Macromolecule depalmitoylation 0.7097958321316975 1.7324372986111638 0.0831957318751719 1.0 0.5219576624760454 6 Q9NUJ1,P50897,Q9UMR5 3 +Regulation of peptidyl lysine acetylation 0.485704692852386 1.732235159604984 0.0832317013211609 1.0 0.5219576624760454 22 O75844,Q03164,Q9NPI1,P38398,Q96EB6,Q92830,Q01105 7 +Cellular modified amino acid metabolic process 0.383319782354647 1.7313215324391849 0.0833944330761626 1.0 0.5219576624760454 53 P00374,P31939,Q9UHG3,O60725,Q9H7Z7,P23786,P21266 7 +Cellular response to inorganic substance 0.4068083730470274 1.730318250618751 0.083573430552774 1.0 0.5219576624760454 42 P09874,P30536,O95831,P31749,P05067,P09601 6 +Cellular response to insulin like growth factor stimulus 0.8103281575582588 1.7271969704480377 0.0841322947609048 1.0 0.5233064172029054 4 Q96A49,P46108 2 +Regulation of t cell apoptotic process 0.7545326200223339 1.7270701536186497 0.0841550650650033 1.0 0.5233064172029054 5 P00813,Q99576 2 +Mrna 5 splice site recognition 0.7082966354027453 1.7254128491257603 0.0844530973368737 1.0 0.5242109476136607 6 O75475,Q07955,Q8WXF0 3 +Nuclear pore organization 0.5592996394151406 1.7252017215100872 0.0844911255677201 1.0 0.5242109476136607 12 P49790,P52948,Q9NQC3,P57740,P12270,Q9BTX1,Q8N1F7 7 +Calcium import into the mitochondrion 0.7080304361670982 1.7241651498963535 0.0846780335234689 1.0 0.5248763526680496 6 P21796 1 +Detection of biotic stimulus 0.7536019689554931 1.7229321432742362 0.0849007968022479 1.0 0.5253320720737489 5 Q8WTV0 1 +Regulation of binding 0.3385996301495247 1.7228756654868973 0.0849110118012661 1.0 0.5253320720737489 107 Q9Y2S7,Q8IXJ6,Q7Z5K2,P50750,Q9UBB9,Q00403,P16949,P41440,Q9H1E3,P31749,Q96HY6,O14981,O75381,P35611,P48681,O75503,Q7KZI7,P09601,P09874,P0DP25,O60869,P46108,P40855,Q08379,O75844,P05067,Q96BK5 27 +Olefinic compound metabolic process 0.4844232691593967 1.7224055769457831 0.0849960741390043 1.0 0.5253650398704499 22 Q9H7Z7,O14734,P07099,P34913,O94788 5 +Response to zinc ion 0.7531144596220118 1.7207639747266852 0.0852936620868884 1.0 0.5262771921435091 5 P09874,P30536 2 +Arachidonic acid metabolic process 0.6760820923055761 1.720710386512454 0.0853033906828453 1.0 0.5262771921435091 7 P07099 1 +Respiratory chain complex iii assembly 0.6750021107544816 1.7154212407497729 0.0862680238415627 1.0 0.5289847474529257 7 Q69YU5,Q6DKK2 2 +Vitamin transmembrane transport 0.6748820561091978 1.714833136032803 0.0863758244239871 1.0 0.5289847474529257 7 Q8WTV0 1 +Response to hepatocyte growth factor 0.636231224887381 1.7131047458008126 0.0866932711067409 1.0 0.5298905040095697 8 P46108,Q8IXJ6 2 +Cellular response to molecule of bacterial origin 0.4283031022761041 1.7046177859994391 0.0882657320023991 1.0 0.5349806112007806 33 Q8IXJ6,P08670,P30536,Q53EL6,Q96JM3,Q8WTV0,O43823,P14174,P31749 9 +Positive regulation of antigen receptor mediated signaling pathway 0.7488953355526644 1.701984690968875 0.0887582381254119 1.0 0.5349806112007806 5 P00813 1 +Nucleobase containing compound transport 0.3283043912165782 1.7008034224696131 0.0889799064051188 1.0 0.5349806112007806 117 Q07955,Q8TD16,Q9ULX6,P35658,P52948,O60318,Q9H814,Q86V81,P22626,Q9UPR3,P49790,P41440,O00400,Q99808,Q08J23,P49792,P09651,Q96PU8,Q96ST2,Q8NFH4,Q53F19,P37198,P67809,Q06787,Q99567,Q9BVL2,Q6I9Y2,O15504,Q9BZI7,Q9BSK2,Q92945,Q8N1F7,Q9BTX1,Q13546,P51991,P57740,P41208,Q07666,P82979 39 +Regulation of low density lipoprotein particle clearance 0.7485618069037305 1.7004990214472402 0.0890371003108712 1.0 0.5349806112007806 5 Q92945 1 +Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 0.9142446043165464 1.6999245983261255 0.0891451093418358 1.0 0.5349806112007806 2 P09601 1 +Blood vessel endothelial cell proliferation involved in sprouting angiogenesis 0.9142446043165464 1.6999245983261255 0.0891451093418358 1.0 0.5349806112007806 2 P09601 1 +Bile acid metabolic process 0.5803796227826693 1.6990355322967616 0.0893124888887806 1.0 0.5349806112007806 11 Q9H4L5,Q96EB6,O14734,Q9BZF3 4 +Cellular response to reactive nitrogen species 0.6330434511827531 1.6964746457882234 0.0897960277857792 1.0 0.5349806112007806 8 O95831 1 +Response to nitric oxide 0.6330434511827531 1.6964746457882234 0.0897960277857792 1.0 0.5349806112007806 8 O95831 1 +Cellular component disassembly 0.3120575842761506 1.6954091910208142 0.0899978235745662 1.0 0.5349806112007806 172 P21796,Q9ULX6,Q9UBB9,Q13501,O95831,P16949,P25054,P41440,Q9Y6I9,O00165,P30536,Q9H444,P27544,P28289,Q9HD42,Q9ULW0,Q01105,Q9NRR5,Q9NYL9,Q9Y4P1,O75381,Q9Y3E1,P35611,P48681,Q9UHB6,Q9Y3D6,Q7KZI7,O95721,Q9UII2,Q969G3,Q96JB5,Q08379,Q86Y91,O75844,P05771 35 +Lysosomal lumen acidification 0.8024762453210558 1.6942711136665831 0.0902137770004718 1.0 0.5349806112007806 4 O75787,P50897,O75503 3 +Mitochondrial calcium ion transmembrane transport 0.6184317597408041 1.693291925851364 0.0903999142443163 1.0 0.5349806112007806 9 P21796 1 +Pointed end actin filament capping 0.9125179856115104 1.6927488643326023 0.0905032798474994 1.0 0.5349806112007806 2 Q9NYL9 1 +Lens fiber cell development 0.91251798561151 1.692748864332601 0.0905032798474996 1.0 0.5349806112007806 2 P08670 1 +Lens fiber cell differentiation 0.91251798561151 1.692748864332601 0.0905032798474996 1.0 0.5349806112007806 2 P08670 1 +Detection of stimulus 0.5165268547444835 1.6918380764091154 0.0906768514470375 1.0 0.5349806112007806 18 Q8WTV0,P30536,Q13432 3 +Humoral immune response mediated by circulating immunoglobulin 0.911942446043165 1.690356511009152 0.090959769785553 1.0 0.5349806112007806 2 Q9UQ84 1 +Neuron death 0.3483146247962312 1.690240483755517 0.0909819561803031 1.0 0.5349806112007806 81 P51858,O95831,Q96EB6,O95630,Q9UMX5,Q9H444,P22681,Q9UGN5,P31749,Q01105,Q9UL15,P31751,Q9NR28,Q15392,P48681,P09601,Q9UER7,Q15233,O75312,P09874,Q99720,P05067,P50897 23 +Proteoglycan biosynthetic process 0.6177630904868374 1.6897019970403226 0.0910849810177443 1.0 0.5349806112007806 9 Q8WVQ1,Q99805,Q8N6G5,Q8NCH0,Q96L58 5 +B cell activation involved in immune response 0.5161914671080126 1.6895242360538458 0.0911190113510644 1.0 0.5349806112007806 18 P43246,O96028,Q04721,Q9UQ84,Q12888,Q96FV9,P00813,Q5RKV6,Q5UIP0 9 +Regulation of muscle cell differentiation 0.4666173887597623 1.6894714807685522 0.0911291127215194 1.0 0.5349806112007806 24 P67809,Q53EL6,P50750,Q8NEZ5,Q9BYT8,Q9UGN5,Q96EB6,Q92830 8 +Phospholipid dephosphorylation 0.6696564803751657 1.6892072099784003 0.0911797277854722 1.0 0.5349806112007806 7 P34913 1 +Positive regulation of myeloid leukocyte differentiation 0.7450468353231839 1.6848319468242188 0.0920209993691851 1.0 0.5370611580022082 5 O00165,Q04721 2 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.940577811590814 1.684796435613489 0.0920278528567744 1.0 0.5370611580022082 3 P30536 1 +Ether metabolic process 0.6167754036160176 1.6843974244289688 0.092104888229245 1.0 0.5370611580022082 9 O15228,P07099,P34913 3 +Amp biosynthetic process 0.5517038412851406 1.6789761430197985 0.0931566933771996 1.0 0.5392032168264743 12 P55263,P31939 2 +Purine nucleotide transport 0.5516946970325256 1.6789203904068302 0.0931675600361006 1.0 0.5392032168264743 12 Q99808,O00400 2 +Negative regulation of nervous system development 0.5063907457159504 1.678655504076018 0.0932192025352491 1.0 0.5392032168264743 19 P30536,Q8IXJ6 2 +Organic cyclic compound catabolic process 0.3156372708319169 1.6767822496408005 0.0935850699945322 1.0 0.5392032168264743 189 P51116,O60506,Q13126,Q9Y2W1,P30519,Q9Y5A9,Q8WTV0,Q9H814,Q9P2K5,Q13148,O95831,P98175,Q9H773,P34913,Q969T7,Q14011,Q99729,Q13151,Q08J23,P35610,P49902,Q02252,Q9BQG2,P21964,Q9Y3Z3,Q9BQ61,P00813,P31749,Q9NRN7,P67809,P08670,P35637,P52272,Q6Y7W6,P09601,Q92804,Q6PJT7,Q86VM9,Q92945,P51114,O75312,O95453,P62312,P33527,Q5RKV6 45 +Intermediate filament based process 0.5512566035470624 1.676249041829884 0.0936894217598791 1.0 0.5392032168264743 12 Q16352,P07197,P08670 3 +Mitotic chromosome condensation 0.5499588461673748 1.668332453440383 0.0952497489251118 1.0 0.544319684013497 12 Q9ULX6,O43823 2 +Nucleotide transport 0.5339734681839587 1.66746331016429 0.0954223141046901 1.0 0.544361582368661 15 Q99808,O00400,P41440 3 +Nucleoside monophosphate catabolic process 0.7407313700373082 1.6655722745250183 0.0957986371928099 1.0 0.5445847511406468 5 P49902 1 +Zinc ion transport 0.9056115107913664 1.664026577769461 0.0961071182138137 1.0 0.545434799234125 2 Q8NEW0 1 +Gmp salvage 0.7941692703075236 1.6593566556933677 0.0970439449929498 1.0 0.5483898401016697 4 P55263 1 +Regulation of response to biotic stimulus 0.345774176694728 1.6498233916193132 0.0989790630160749 1.0 0.5496762663596315 74 Q14166,P23246,Q8IXJ6,O75844,Q9Y5A9,Q8WXF1,Q9UKG1,P12956,P04439,Q07021,Q86UT6,Q9Y3Z3,P46108,P14174,P43243,Q96PK6,Q9NZ08,Q6UWE0 18 +Histone deacetylation 0.4223487572364747 1.6486698735935232 0.0992152852945416 1.0 0.5496762663596315 33 Q8IXJ6,Q9ULX6,O95983,Q9NTG7,Q96PK6,O43823,Q96EB6,Q92830 8 +Deoxyribonucleoside monophosphate metabolic process 0.6238806895294997 1.6485492587234991 0.0992400112736 1.0 0.5496762663596315 8 P55263 1 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.3746777003817378 1.6472123916879666 0.0995143976621899 1.0 0.5496762663596315 54 P53999,P09874,Q04721,O00400,P08670,Q9UKG1,Q53EL6,Q9Y2U8,Q9UIQ6,Q96PK6,Q96EB6,Q92896,Q8N1F7 13 +Nuclear pore complex assembly 0.6096604777349599 1.64611888103543 0.0997392858769368 1.0 0.5496762663596315 9 P49790,P52948,P57740,P12270,Q9BTX1,Q8N1F7 6 +Regulation of steroid biosynthetic process 0.571163126142255 1.6455672258124925 0.0998528914138781 1.0 0.5496762663596315 11 Q96EB6,P30536 2 +Protein targeting to peroxisome 0.9297639608520432 1.643222785277073 0.1003368472453423 1.0 0.5496762663596315 3 O75381,P56589 2 +Carbohydrate derivative transport 0.5011524762209959 1.641498990709935 0.1006938764191647 1.0 0.5496762663596315 19 Q99808,Q8WTV0,O00400 3 +Purine nucleoside monophosphate metabolic process 0.4606422621417695 1.6413035541602612 0.1007344186981078 1.0 0.5496762663596315 24 P55263,P31939,P49902 3 +Cellular response to cadmium ion 0.690360113237479 1.6410612788582215 0.100784695485165 1.0 0.5496762663596315 6 P09601,P31749 2 +Negative regulation of response to external stimulus 0.3741278734571494 1.6406524712156632 0.1008695762708582 1.0 0.5496762663596315 54 Q14166,Q9UMX5,Q8IXJ6,P28070,Q9Y5A9,P80303,P04439,Q07021,P46108,Q9Y3Z3,P14174,Q96G23,P00813 13 +Cellular response to chemical stress 0.3446779682177939 1.639741600804037 0.101058905260162 1.0 0.5496762663596315 82 P09874,P00374,Q8IXJ6,Q9NR28,Q99720,P30536,P31749,O95831,Q7Z2K6,P33527,P09601 11 +Negative regulation of organic acid transport 0.7893911497331622 1.6392381974983972 0.1011636615653561 1.0 0.5496762663596315 4 P31751,P31749 2 +Chloride transport 0.5351712392778777 1.6389838308737643 0.1012166271747654 1.0 0.5496762663596315 14 P08183,Q9UHG3 2 +Positive regulation of smad protein signal transduction 0.8995683453237404 1.6388708659126436 0.1012401564385445 1.0 0.5496762663596315 2 P09874 1 +Negative regulation of glial cell proliferation 0.9285885847720934 1.6386992396967526 0.1012759124845337 1.0 0.5496762663596315 3 P30536 1 +Positive regulation of long term synaptic potentiation 0.7343616657958545 1.63709638444642 0.1016103319385459 1.0 0.5505842739663481 5 P05067 1 +Response to interleukin 1 0.5231994325483506 1.6366289831614982 0.1017080158732937 1.0 0.5506607367207331 16 Q96JM3,P05067,P38159 3 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.6891894460240326 1.6355366027964509 0.101936608087749 1.0 0.5508390799377254 6 P46934 1 +Nucleolus organization 0.5397629123493284 1.6352194739008326 0.1020030472245321 1.0 0.5508390799377254 13 Q9UPP1,Q8IXJ6 2 +B cell proliferation 0.5387514028607128 1.6289171877830235 0.1033305510100552 1.0 0.5511530344712616 13 P00813,Q96IZ0 2 +Long chain fatty acid transport 0.5334783043918625 1.6282372559380691 0.1034745878875553 1.0 0.5511530344712616 14 P31751,O43772,P31749,P23786 4 +Nucleobase containing small molecule biosynthetic process 0.656881493743167 1.626337731520628 0.1038778293031441 1.0 0.5511530344712616 7 P55263,P00813 2 +Glycosyl compound biosynthetic process 0.656881493743167 1.626337731520628 0.1038778293031441 1.0 0.5511530344712616 7 P55263,P00813 2 +Dermatan sulfate proteoglycan metabolic process 0.8964028776978412 1.6256859501948198 0.104016480380028 1.0 0.5511530344712616 2 Q8NCH0 1 +Regulation of monooxygenase activity 0.542754732702654 1.6242979523697498 0.1043122340560573 1.0 0.5511734644710201 12 P31749,Q8WTV0,P00374,P0DP25 4 +Proteoglycan metabolic process 0.5915226926374664 1.6234829833743143 0.1044861981005373 1.0 0.5516502878881737 10 Q8WVQ1,Q99805,Q8N6G5,Q8NCH0,Q96L58 5 +Phospholipid metabolic process 0.3426474643920018 1.6179934698574567 0.1056640049763664 1.0 0.5560863648476663 85 P37268,Q8IY17,Q6UWP7,Q9HBU6,Q9NPH0,Q8WTV0,Q8NHP8,P35790,O95749 9 +Histone h3 k9 trimethylation 0.6846101665106631 1.6139040573000711 0.1065482384839189 1.0 0.5583861418460269 6 Q96EB6,Q5T5X7 2 +Mrna cis splicing via spliceosome 0.488483818500086 1.611688042046173 0.1070298411151093 1.0 0.5596981135773458 20 O75475,Q07955,Q9Y2W2,O75400,Q8WXF0,Q15459,Q9P013,Q96I25 8 +Protein poly adp ribosylation 0.9210093919053496 1.6095087096560008 0.107505152085578 1.0 0.5599167719726109 3 Q9UGN5 1 +Purine containing compound salvage 0.6162274178467819 1.6083823048550552 0.1077514747095569 1.0 0.5599167719726109 8 P55263,P00813 2 +Transition metal ion homeostasis 0.445459899130658 1.6053365955689674 0.1084197496659042 1.0 0.5616177126954743 27 Q8NEW0,P30519,Q9Y5Y0,P09601,P05067 5 +Pteridine containing compound metabolic process 0.5112395902363814 1.6036106965628496 0.1087998914727303 1.0 0.5618939355174616 17 P61457,P31939,P00374,P41440 4 +Histone h3 deacetylation 0.6819307387185588 1.6012306169046395 0.109325849951948 1.0 0.5618939355174616 6 Q96EB6,Q8IXJ6 2 +Positive regulation of t cell proliferation 0.5870079581766772 1.598384977641333 0.1099573258013473 1.0 0.5638200931557024 10 P04439,P30825,P49366,Q9HCL2 4 +Positive regulation of cell population proliferation 0.2976029135618699 1.5915044087954693 0.1114961040170667 1.0 0.5708219342412222 137 O43663,Q9P032,Q9UPN4,Q7Z5K2,P49366,P04439,Q96JM3,Q9UBL3,Q96EY1,O95684,Q96EB6,Q00577,O94788,P43490,O95630,P30536,Q9HCL2,Q9P266,P33981,P82970,Q52LJ0,P00813,P31749,Q96HY6,Q15058,P31751,P55209,Q04721,Q96ER3,P30825,Q14978,P48681,O43379,P09601,Q01085,Q86X55,Q9BSK2,Q6ZWJ1,P43307,P14174,Q9H2J4,Q86Y37 42 +Photoreceptor cell maintenance 0.7758312926481674 1.5820098348455105 0.1136473253416352 1.0 0.5747412420909421 4 P11166,Q15051 2 +Histone h4 k20 methylation 0.6776233609929068 1.5808332614840517 0.1139161671784181 1.0 0.5747412420909421 6 Q5T5X7,Q14166,O96028,P38398 4 +Regulation of microtubule depolymerization 0.5308699271687743 1.5797123276997798 0.1141727611673202 1.0 0.5747412420909421 13 Q9Y3E1,P25054 2 +Collagen biosynthetic process 0.7752597211832492 1.5795934189368177 0.114200007353358 1.0 0.5747412420909421 4 P08670 1 +Regulation of long chain fatty acid import across plasma membrane 0.9127686006183388 1.5777309242868645 0.1146274387563788 1.0 0.5747412420909421 3 P31749 1 +Muscle cell differentiation 0.3398495082240653 1.5750950647644089 0.1152345030555439 1.0 0.5747412420909421 69 P67809,P02545,P41440,Q9NYL9,Q9H7B4,Q99523,O75844,Q53EL6,Q8NEZ5,Q96PU8,P28289,Q9BYT8,Q9UGN5,Q9P2K5,Q96EB6,P31749,Q92830 17 +Positive regulation of reproductive process 0.6096186505036577 1.5736017261488249 0.11557955394905 1.0 0.5747412420909421 8 Q8IXJ6 1 +Regulation of lysosomal lumen ph 0.7198268919931504 1.571914045738544 0.1159704866657647 1.0 0.5747412420909421 5 O75787,P50897,O75503 3 +Retinoic acid metabolic process 0.911202768590367 1.571688549989713 0.116022798901525 1.0 0.5747412420909421 3 O94788 1 +Embryonic heart tube development 0.6755309557755396 1.570914386187472 0.1162025365023717 1.0 0.5747412420909421 6 Q15363,P42892 2 +Tubulin deacetylation 0.6754849875648918 1.5706964024512706 0.1162531852402695 1.0 0.5747412420909421 6 Q8IXJ6 1 +Positive regulation of jnk cascade 0.6087061505072553 1.568792712988166 0.1166962469168457 1.0 0.5751021472962579 8 P05067 1 +Glycoside catabolic process 0.6746111473160337 1.5665519944186912 0.1172194462530156 1.0 0.575360431500692 6 Q9NUJ1 1 +Hormone metabolic process 0.4236304380185968 1.566384506990702 0.1172586277864713 1.0 0.575360431500692 31 P30536,O75844,P42892,O94788 4 +Positive regulation of necrotic cell death 0.6740842049879122 1.564052278832943 0.1178052916189749 1.0 0.575360431500692 6 P30536,Q13546 2 +Lipid biosynthetic process 0.3030646373264019 1.563916037862498 0.117837287609027 1.0 0.575360431500692 164 P37268,Q6UWP7,Q9BZF3,Q9NPH0,O15228,O14734,Q8WTV0,Q8TBX8,Q8NCC3,Q9BY49,Q10713,O94788,O00116,Q9HBU6,Q8NBX0,P30536,Q96PU8,P27544,Q9NTG7,Q9H4L5,Q06136,P31749,Q16739,Q15392,Q9H7Z7,P35790,Q16850,P48449,P14174,Q96G23,O95749 31 +Response to testosterone 0.5326204178359758 1.5621114359884438 0.1182617392801381 1.0 0.575360431500692 12 P22681,P30536,Q13126,P49321 4 +Positive regulation of histone acetylation 0.5804819011701512 1.562025369192319 0.1182820125546979 1.0 0.575360431500692 10 Q9NPI1,Q92830 2 +Regulation of histone h4 k16 acetylation 0.7171661249448309 1.5599525562196344 0.1187710932620031 1.0 0.5759791060886299 5 O75844,Q96EB6 2 +Regulation of histone h4 acetylation 0.6062189258412035 1.5556765999961022 0.1197850136201554 1.0 0.5786388964392994 8 O75844,Q96EB6,P38398 3 +Negative regulation of blood pressure 0.7689321473247974 1.552821472261254 0.1204657914125713 1.0 0.580953728715461 4 P42785 1 +Nucleobase containing small molecule catabolic process 0.7154520287141655 1.5522423052532357 0.1206042570116148 1.0 0.580953728715461 5 P00813 1 +Steroid biosynthetic process 0.3728431183846708 1.5493504609190365 0.1212974955710066 1.0 0.58380511199223 49 P37268,Q16850,Q9BZF3,P30536,Q15392,O14734,Q9H4L5 7 +Gmp metabolic process 0.5098606102011825 1.5482670714408475 0.1215580089529244 1.0 0.5846319131319848 16 P55263,P31939 2 +Sterol metabolic process 0.3892278742241747 1.5453156913562842 0.1222699218221254 1.0 0.5870672279896119 42 P37268,O75845,Q16850,Q9BQE5,P48449,P35610,Q15392,P05067,Q9UHB6,Q8WTV0,P34913 11 +Striated muscle cell differentiation 0.3724053489642282 1.5443179020198043 0.1225113377784394 1.0 0.5870672279896119 49 P67809,P41440,Q9NYL9,Q9H7B4,Q99523,Q8NEZ5,P28289,Q9BYT8,Q9UGN5,Q9P2K5,O75844,P31749,Q92830 13 +Regulatory t cell differentiation 0.8765467625899273 1.5428753171783816 0.1228610306756827 1.0 0.5870672279896119 2 Q92830 1 +Purine nucleoside monophosphate biosynthetic process 0.5146581146541929 1.5421867377869147 0.1230282219164506 1.0 0.5870672279896119 15 P55263,P31939 2 +Benzene containing compound metabolic process 0.6397189021878619 1.5414115852506018 0.1232166461883608 1.0 0.5870672279896119 7 P34913 1 +Folic acid containing compound metabolic process 0.5197753891141735 1.540950860941115 0.1233287458952412 1.0 0.5870672279896119 14 P31939,P00374,P41440 3 +Phospholipid transport 0.5197330721624219 1.540680510580798 0.1233945624179235 1.0 0.5870672279896119 14 Q14108,P08183,Q8WTV0,P33527 4 +Folic acid metabolic process 0.6395183574360532 1.540416284629776 0.1234589144544275 1.0 0.5870672279896119 7 P00374 1 +Negative regulation of fatty acid transport 0.90299366724237 1.5399900704183649 0.1235627738280364 1.0 0.5870672279896119 3 P31751,P31749 2 +Long chain fatty acid import across plasma membrane 0.7657978277570896 1.539546348558587 0.1236709718963491 1.0 0.5870672279896119 4 P31751,P31749 2 +Response to oxygen glucose deprivation 0.8756834532374089 1.53927149140154 0.1237380307250202 1.0 0.5870672279896119 2 O95831 1 +Cellular response to oxygen glucose deprivation 0.8756834532374089 1.53927149140154 0.1237380307250202 1.0 0.5870672279896119 2 O95831 1 +Regulation of neurotransmitter levels 0.4158072068880372 1.5390721211134442 0.1237866902494957 1.0 0.5870672279896119 32 Q4J6C6,P41440,P0DP25,Q99808,P21964,Q5SQN1,O95721,P50897,P05771 9 +Vascular endothelial growth factor receptor signaling pathway 0.5527098355623437 1.5378667211222583 0.1240812056760736 1.0 0.5877577744066492 11 P46934 1 +Nucleotide salvage 0.6384791778564878 1.535257815682054 0.1247205117136616 1.0 0.5886700943275905 7 P55263 1 +Peptidyl threonine modification 0.3995337806967359 1.5330746925118464 0.1252574524060743 1.0 0.5897897620016125 37 Q8IXJ6,P0DP25,P31749,P05067,P05771 5 +Negative regulation of fat cell differentiation 0.6673786783893676 1.5322065842798565 0.1254714642640531 1.0 0.5897897620016125 6 Q99523,Q8IXJ6,Q8N4Q0 3 +Negative regulation of protein maturation 0.7106631407762434 1.530682929066396 0.1258477748123725 1.0 0.5897897620016125 5 Q92896 1 +Regulation of dna methylation 0.5511888070470033 1.5289537028599436 0.1262759215930722 1.0 0.5897897620016125 11 P09874,Q03164,O95983,O75844 4 +Nuclear membrane reassembly 0.5178953268202169 1.5289352196550368 0.1262805040510999 1.0 0.5897897620016125 14 Q9HD42,Q86XL3,Q8IXJ6 3 +Purine nucleoside monophosphate catabolic process 0.7631048253228869 1.5281333795707597 0.1264794253617056 1.0 0.5897897620016125 4 P49902 1 +Ribonucleoside monophosphate catabolic process 0.7631048253228869 1.5281333795707597 0.1264794253617056 1.0 0.5897897620016125 4 P49902 1 +Regulation of endodeoxyribonuclease activity 0.6644648073495586 1.518347914919912 0.1289267145688946 1.0 0.5927198799550814 6 P31749 1 +Embryonic heart tube morphogenesis 0.8705035971223013 1.5176441765096749 0.1291041238503028 1.0 0.5927198799550814 2 Q15363 1 +Positive regulation of keratinocyte proliferation 0.8705035971223014 1.5176441765096749 0.1291041238503028 1.0 0.5927198799550814 2 Q6ZWJ1 1 +Mature b cell differentiation 0.8705035971223012 1.517644176509674 0.129104123850303 1.0 0.5927198799550814 2 P00813 1 +Regulation of b cell proliferation 0.5857737469233425 1.516808632206477 0.1293150069767217 1.0 0.5927198799550814 9 P00813,Q96IZ0 2 +Regulation of histone h2b ubiquitination 0.7075079559346311 1.5164641660376854 0.1294020246772271 1.0 0.5927198799550814 5 Q5VTR2,O75150 2 +Regulation of long chain fatty acid import into cell 0.758628116061957 1.5091472862282145 0.1312611477695799 1.0 0.5981187431907071 4 P31749 1 +Nerve development 0.632556707819644 1.5058263106211518 0.1321117672501444 1.0 0.6010516413371386 7 P42892 1 +Cellular hormone metabolic process 0.4821203167202016 1.5056875992738945 0.1321473888353521 1.0 0.6010516413371386 19 P30536,P42892,Q9HB40,O94788 4 +Positive regulation of carbohydrate metabolic process 0.5836532900872594 1.5052748272796377 0.1322534342224965 1.0 0.6010516413371386 9 P31751,P31749,P05067 3 +Regulation of membrane potential 0.3396333674121918 1.5052116392770607 0.1322696736893081 1.0 0.6010516413371386 66 P31751,P09874,Q9UQB8,Q99808,P30536,O75844,P31749,P05067,P46934 9 +Embryonic camera type eye development 0.8673381294964018 1.5044242915127777 0.1324721534961641 1.0 0.6015568707003622 2 O94788 1 +Positive regulation of vasculature development 0.456104065893626 1.503370974492369 0.1327434071001216 1.0 0.6019589190521003 22 Q9P266,P38398,Q96JM3,P09601,Q9H2J4,Q96EB6,Q9NZ08,P05771 8 +Negative regulation of cell development 0.4435506384038856 1.5026400201421228 0.1329318974709297 1.0 0.6023990869573286 24 P30536,Q8IXJ6 2 +Diacylglycerol metabolic process 0.7567245619973446 1.5010691447633906 0.1333376784250213 1.0 0.6032852786838064 4 Q8NCC3 1 +Intestinal lipid absorption 0.8661870503597113 1.499616556718471 0.1337137564087693 1.0 0.6032852786838064 2 Q16739 1 +Positive regulation of glucose transmembrane transport 0.5955011111083688 1.4990277343896992 0.1338664372452496 1.0 0.6032852786838064 8 P31751,P31749,Q16625 3 +Dna packaging 0.3318306325640935 1.497288320128981 0.1343182526820057 1.0 0.6032876393467863 94 Q8IXJ6,P16104,Q9H7B4,Q9ULX6,Q7Z5K2,Q9UK61,O95831,Q96EB6,Q9HD42,Q01105,P55209,Q5T5X7,O95983,O43823,Q8N7H5,Q8NEY8,Q9UPP1,Q99733,P49321 19 +Isoprenoid metabolic process 0.4286834303968853 1.4951375642353737 0.1348785440451034 1.0 0.6053915032106176 28 P37268,Q9HB40,Q6NUM9,Q9BY49,O95749,O94788 6 +Positive regulation of histone deacetylation 0.6302480021770648 1.4943387396674142 0.1350871045031536 1.0 0.6054800308341406 7 Q9ULX6,O43823 2 +Folic acid containing compound biosynthetic process 0.7023893104325833 1.4933741194043897 0.1353392836394138 1.0 0.6054800308341406 5 P00374 1 +Tetrahydrofolate biosynthetic process 0.7023893104325833 1.4933741194043897 0.1353392836394138 1.0 0.6054800308341406 5 P00374 1 +Cellular modified amino acid catabolic process 0.6296128778084346 1.4911771224000658 0.135914998404526 1.0 0.6063262860442938 7 Q8WUX2,Q9UHG3 2 +Positive regulation of chromosome segregation 0.5937377300735511 1.4896881787965277 0.1363062442697835 1.0 0.6072493870815442 8 Q9NS91,Q8IXJ6 2 +Homologous chromosome segregation 0.5203142984653872 1.4862495646097096 0.1372131217698553 1.0 0.6093173125588855 12 Q92791,Q9BTX1,Q9BXW9 3 +Activation of immune response 0.3582217136937435 1.4861751608223632 0.1372327958472281 1.0 0.6093173125588855 56 P23246,P46379,Q8WXF1,Q9UJ41,Q9UKG1,Q07666,P12956,P04439,Q07021,Q96PK6,Q96IZ0,P43243,P00813,Q15233,O60828,P05771 16 +Endocrine system development 0.4936208519672314 1.4837581936079058 0.1378730817121187 1.0 0.6106320045458187 17 P30536,O94788 2 +Response to l glutamate 0.7526457636783391 1.483750282860002 0.13787518114585 1.0 0.6106320045458187 4 O95831 1 +Response to bacterium 0.3356065906028541 1.4836442607258813 0.1379033207429962 1.0 0.6106320045458187 67 Q9UQB8,Q04721,P51812,Q13151,Q8IXJ6,Q9BTY2,P08670,P30536,Q53EL6,Q96JM3,Q8WTV0,O43823,P14174,P31749,Q9NZ08 15 +Positive regulation of striated muscle cell differentiation 0.7001600030567575 1.483309241432338 0.1379922681391294 1.0 0.6106320045458187 5 Q9UGN5 1 +Regulation of antigen receptor mediated signaling pathway 0.566275718758783 1.482569609830094 0.1381887963980115 1.0 0.6107132004861883 10 P00813,P05771 2 +T cell apoptotic process 0.5104643147240118 1.4813562658202126 0.1385116623143902 1.0 0.6107525213840905 14 P24390,Q13546,Q9HCL2,Q99576,Q96EY1,P00813,P31749 7 +Regulation of t cell proliferation 0.4861318160639236 1.4805910797382906 0.1387155738427621 1.0 0.6107525213840905 18 P30825,P49366,Q9HCL2,P04439,Q96IZ0 5 +Secondary alcohol metabolic process 0.3718553273721852 1.4804163239239887 0.1387621762732414 1.0 0.6107525213840905 46 P37268,O75845,Q16850,Q9BQE5,P48449,P35610,Q15392,P48735,P05067,Q9UHB6,Q8WTV0,P34913 12 +Ceramide metabolic process 0.4435785308611793 1.479332504510989 0.1390514695984841 1.0 0.6107525213840905 23 Q96G23,Q99805,Q16739,P27544,Q9NTG7,Q8NCC3 6 +Positive regulation of response to oxidative stress 0.8607194244604308 1.4767768947915492 0.1397354520311577 1.0 0.6107525213840905 2 Q96IZ0 1 +Positive regulation of response to reactive oxygen species 0.8607194244604308 1.4767768947915492 0.1397354520311577 1.0 0.6107525213840905 2 Q96IZ0 1 +Neurotransmitter transport 0.4217870511720308 1.4700474051784882 0.1415489153959546 1.0 0.6148831349547869 29 Q4J6C6,Q9P253,P41440,P0DP25,Q99808,Q5SQN1,O95721,P50897,P05771 9 +Amino acid transmembrane transport 0.5086913218441268 1.4699846916098205 0.1415659000950693 1.0 0.6148831349547869 14 P30825,Q9Y619,Q96NB2 3 +Negative regulation of protein containing complex disassembly 0.4129856623799814 1.4690957654700825 0.1418068161597603 1.0 0.6155237889833075 31 Q9NRR5,P25054,Q9NYL9,Q9Y3E1,P35611,P28289,Q9ULW0 7 +Regulation of hormone levels 0.3325954552608275 1.4685596063780832 0.1419522777702275 1.0 0.6157484376919988 71 O00233,Q8N183,Q15043,P42892,P30536,Q9HB40,P53985,Q6NUM9,O75844,P00367,O94788 11 +Regulation of response to food 0.8584172661870494 1.4671590969195845 0.1423327809567913 1.0 0.6157785250980291 2 Q9UMX5 1 +Regulation of appetite 0.8584172661870494 1.4671590969195845 0.1423327809567913 1.0 0.6157785250980291 2 Q9UMX5 1 +Negative regulation of response to food 0.8584172661870494 1.4671590969195845 0.1423327809567913 1.0 0.6157785250980291 2 Q9UMX5 1 +B cell mediated immunity 0.4765031047212239 1.4653842446028142 0.1428161135370604 1.0 0.6160652511581524 19 P43246,Q96QE3,O96028,Q9UQ84,Q96FZ2,Q7KZ85,Q12888,Q07021,Q96FV9,Q9NQT5,Q5RKV6,O60934,Q5UIP0 13 +Tetrahydrofolate metabolic process 0.5630976844446566 1.464741524067795 0.1429914512745647 1.0 0.6160652511581524 10 P00374 1 +Peptidyl lysine deacetylation 0.8831773934259888 1.463353823003924 0.1433705871646775 1.0 0.6160652511581524 3 Q8IXJ6 1 +Mammary gland epithelium development 0.5882329485894067 1.4604999211733192 0.1441527291914308 1.0 0.6169885976786899 8 P31749 1 +Behavioral response to pain 0.7453313381817129 1.4526620393863692 0.1463176116317961 1.0 0.6199338619726208 4 P30536 1 +Response to pain 0.745331338181713 1.4526620393863692 0.1463176116317961 1.0 0.6199338619726208 4 P30536 1 +Neural crest cell differentiation 0.5379533174033928 1.4511895702042517 0.1467270803304874 1.0 0.6199338619726208 11 O94788 1 +Mesenchymal cell development 0.5379533174033928 1.4511895702042517 0.1467270803304874 1.0 0.6199338619726208 11 O94788 1 +Cellular response to interleukin 1 0.5379308103174529 1.4510570349481284 0.1467639790896151 1.0 0.6199338619726208 11 Q96JM3,P38159 2 +Regulation of caveolin mediated endocytosis 0.854388489208632 1.4503270554523418 0.1469673377891764 1.0 0.619953769969836 2 Q13432 1 +Amyloid fibril formation 0.5732760403717442 1.4487153107802229 0.1474171028929756 1.0 0.6210558126354324 9 Q13546,O15212,Q99471,P61758,Q9UHV9,P05067 6 +Response to axon injury 0.4995507746877153 1.4434915191598228 0.1488820598291749 1.0 0.6245801732208269 15 P30536,P00374 2 +Cellular response to lipoprotein particle stimulus 0.742704877744625 1.4414900011278018 0.1494463001259394 1.0 0.6256046197775189 4 P31749 1 +Purine nucleotide salvage 0.6480882852899699 1.4402497984680935 0.1497967388135244 1.0 0.6262758325141575 6 P55263 1 +Purine ribonucleotide salvage 0.6480882852899699 1.4402497984680935 0.1497967388135244 1.0 0.6262758325141575 6 P55263 1 +Response to toxic substance 0.3619671782821063 1.4357615168428273 0.1510702137379092 1.0 0.6284101252014417 50 P08183,P00374,P21266,P07099,O95831,P34913 6 +Synaptic signaling 0.3268607621631524 1.4335380664199742 0.1517041284144737 1.0 0.6288336767583201 96 Q4J6C6,Q9UQB8,P51812,P41440,P0DP25,Q99808,Q15418,Q13432,Q9NR77,Q92830,O95721,P31749,P05067,P50897,P05771 15 +Selective autophagy 0.413315034128402 1.4318811131860745 0.1521778482947349 1.0 0.629070160608881 30 O15269,P21796,Q9Y679,Q9Y4P1,Q9Y6I9,Q96EP0,P27544,Q5T8D3,Q13501,Q96HY6,Q6UWE0 11 +Mrna 3 splice site recognition 0.6883581151352484 1.4299465928065165 0.1527323480094093 1.0 0.629070160608881 5 Q15637,Q15459,O95391 3 +Negative regulation of response to biotic stimulus 0.4315749986766248 1.429556228535717 0.1528444259398353 1.0 0.629070160608881 25 Q14166,Q8IXJ6,Q9Y5A9,P04439,Q07021,P46108,Q9Y3Z3 7 +Somitogenesis 0.5340260979052593 1.4280496614339513 0.1532775649504358 1.0 0.629070160608881 11 Q92830,O94788 2 +Walking behavior 0.7394932857253795 1.427823148373614 0.1533427682494577 1.0 0.629070160608881 4 O75844,O15118 2 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.3255336987259188 1.4269171484671326 0.1536037773084115 1.0 0.629070160608881 98 Q8NEM2,Q8IXJ6,Q99523,Q8TBX8,Q96EB6,P16949,P25054,Q9UKG1,Q9P266,P22681,P31749,P37198,P46934,P31751,Q9UQB8,Q15043,Q6Y7W6,Q6ZWJ1,P46108,Q9HCD5,P05771 21 +Cell aging 0.403722921522211 1.4263178972974764 0.1537766007854664 1.0 0.629070160608881 32 P67809,P02545,P16104,O75844,Q96SB8,Q53EL6,P14174,Q96IZ0,Q96EB6,Q14191,P37198 11 +Amp salvage 0.6872043404664107 1.4247231068856512 0.1542372569921104 1.0 0.629070160608881 5 P55263 1 +Protein containing complex remodeling 0.8480575539568331 1.4238763253042492 0.1544822762045652 1.0 0.629070160608881 2 Q8WTV0 1 +Diol metabolic process 0.6160630088765672 1.4235922254099826 0.1545645477185862 1.0 0.629070160608881 7 P00374 1 +Diol biosynthetic process 0.6160630088765672 1.4235922254099826 0.1545645477185862 1.0 0.629070160608881 7 P00374 1 +Bone morphogenesis 0.5812407099068938 1.4233571469134465 0.1546326484562272 1.0 0.629070160608881 8 O75844,Q92896 2 +Antibacterial humoral response 0.8477697841726608 1.4226740566150695 0.1548306646917931 1.0 0.629216131973577 2 Q96JM3 1 +Cellular lipid catabolic process 0.3311517271460132 1.422130807460508 0.1549882808002907 1.0 0.629216131973577 67 P31751,Q8IY17,Q8IXJ6,Q13011,O75521,Q16134,Q15067,P23786,Q8WTV0,Q8NHP8,Q8NCC3,P31749,P50897 13 +Intracellular distribution of mitochondria 0.7379786927728309 1.421375706095708 0.1552075651982796 1.0 0.6297183787509016 4 O75153,Q92830,Q9NVT9 3 +Protein localization to perinuclear region of cytoplasm 0.8720139661183843 1.4201287223052013 0.1555702097771607 1.0 0.63008064507074 3 Q96ED9 1 +Positive regulation of protein deacetylation 0.5806243677511004 1.4200797267585898 0.1555844716544236 1.0 0.63008064507074 8 P49354,Q96EB6,Q9ULX6,O43823 4 +Response to mineralocorticoid 0.6432948488477124 1.4173288409138471 0.1563868067201741 1.0 0.6310059212977509 6 O95831,P09874 2 +Negative regulation of amyloid fibril formation 0.6852572806185745 1.4159057086634137 0.1568031133219258 1.0 0.6315254973582943 5 Q99471,Q9UHV9,O15212 3 +Negative regulation of amyloid precursor protein biosynthetic process 0.8460431654676247 1.4154605833044418 0.1569334974883227 1.0 0.6316645173796938 2 Q9NY61 1 +Blood vessel endothelial cell migration 0.4296092581282142 1.4132269109712725 0.1575890163215962 1.0 0.632526387528011 25 P06576,Q8WTV0,P09601,P31749,P42785 5 +Regulation of mrna export from nucleus 0.6846237769515598 1.413036188714015 0.1576450838304284 1.0 0.632526387528011 5 Q9ULX6,Q96ST2,Q08J23 3 +Mrna export from nucleus 0.3767197857544409 1.4124428549217038 0.1578196055692897 1.0 0.632526387528011 42 Q8N1F7,Q9UPR3,Q08J23,Q6I9Y2,Q99567,P82979,Q9ULX6,P35658,O60318,P57740,Q53F19,Q86V81,P22626 13 +Regulation of leukocyte apoptotic process 0.4947061820702249 1.4117296628405636 0.1580295757764123 1.0 0.6325983443443381 15 Q96EB6,Q99576,P00813,P14174 4 +Iron ion transport 0.5304691417615554 1.4070679172806653 0.1594072504068862 1.0 0.6356563459711612 11 Q07960,O15173,Q15043,Q9Y5Y0,Q8N4V1 5 +Cellular response to exogenous dsrna 0.6402990979544106 1.402991266548803 0.160619443262824 1.0 0.6381595574766578 6 O60828,P41440 2 +Amp metabolic process 0.4879615592632071 1.402146151033973 0.1608716079782559 1.0 0.6381595574766578 16 P55263,P31939 2 +Positive regulation of smooth muscle cell proliferation 0.5645695895381191 1.4011279375125707 0.1611758186340668 1.0 0.6383314611299901 9 P31749 1 +Dna ligation 0.6101244377842275 1.3938972510409289 0.1633486345365631 1.0 0.6412952545953585 7 P12956 1 +Manganese ion transmembrane transport 0.8647092688543434 1.3918331906344124 0.1639729166964159 1.0 0.6412952545953585 3 Q15043,Q9HD20 2 +Manganese ion transport 0.8647092688543434 1.3918331906344124 0.1639729166964159 1.0 0.6412952545953585 3 Q15043,Q9HD20 2 +Intermediate filament organization 0.6374555086719713 1.38937340726475 0.1647192323801047 1.0 0.6414295661274324 6 P08670 1 +Tumor necrosis factor superfamily cytokine production 0.4656539296511354 1.3873017762979851 0.1653497617028816 1.0 0.6419305194559003 19 P14174,P30536,P05067,O43823 4 +Cellular metabolic compound salvage 0.5041994032802409 1.3864098967659848 0.1656217761534422 1.0 0.6419305194559003 12 P55263,P00813,Q13126 3 +Pigment biosynthetic process 0.4261625493616068 1.3845654657862791 0.1661853773015056 1.0 0.6425259111011308 25 Q9UII2,P36551,P22830,P30536,Q9Y5Y0,P00813,O00264 7 +Negative regulation of map kinase activity 0.5481353810835901 1.3805778749967434 0.1674087900346408 1.0 0.645817633219115 10 P18031,Q96JB5,Q53EL6,P04035,P37198 5 +Positive regulation of macroautophagy 0.464523308260869 1.3791483130553124 0.1678490304546809 1.0 0.6464153667401723 19 P21796,Q96EP0,P27544,Q8TBX8,P09601,Q96EB6,Q6UWE0 7 +Establishment of rna localization 0.3203959797851526 1.378287720793864 0.1681144728415118 1.0 0.6464153667401723 102 Q07955,Q8TD16,P82979,Q9ULX6,P35658,O60318,Q96FV9,Q9H814,Q86V81,P22626,Q96MU7,Q9UPR3,P49790,P41440,Q08J23,Q16629,P49792,P09651,Q96PU8,Q96ST2,Q8NFH4,Q53F19,P37198,P67809,Q06787,Q99567,Q9BVL2,Q6I9Y2,O15504,Q9BZI7,Q9BTX1,Q92945,Q8N1F7,Q86U42,P51991,P57740,P41208,Q07666,P52948 39 +Rna export from nucleus 0.3477675811408844 1.3766912637700623 0.1686077208881813 1.0 0.6464153667401723 57 Q9ULX6,P35658,O60318,Q96FV9,Q9H814,Q96MU7,Q86V81,P22626,Q9UPR3,P49790,Q08J23,P09651,Q96ST2,Q53F19,P37198,Q99567,Q6I9Y2,Q8N1F7,Q86U42,P57740,Q07666,P82979 22 +Regulation of vacuole organization 0.5026246749515522 1.3766277879034978 0.1686273550834376 1.0 0.6464153667401723 12 Q14108,Q8TBX8,Q9H444 3 +Protein insertion into membrane 0.4149876123892104 1.3758665814936253 0.1688629432134079 1.0 0.6464153667401723 28 O43765,P46379,Q9NS69,O43681,Q9P0J0,O14737,Q9Y512,Q15629 8 +Calcium ion import 0.4983691128395795 1.3751900035150153 0.1690725466464466 1.0 0.6464153667401723 13 P21796,O75844 2 +Negative regulation of lipid transport 0.7270745712351101 1.3749226472783938 0.1691554272192461 1.0 0.6464153667401723 4 P31751,P31749 2 +Negative regulation of lipid localization 0.6344237349790258 1.3748456544716394 0.1691793006804507 1.0 0.6464153667401723 6 P31751,P31749 2 +Regulation of i kappab phosphorylation 0.8356834532374089 1.3721886728406345 0.1700047106874018 1.0 0.6471888893106952 2 P31749 1 +Positive regulation of i kappab phosphorylation 0.8356834532374089 1.3721886728406345 0.1700047106874018 1.0 0.6471888893106952 2 P31749 1 +Neuromuscular junction development 0.5006950195109169 1.364635398931352 0.1723676730521979 1.0 0.6487373759327787 12 P46934 1 +Mitochondrial fusion 0.492294458220225 1.3645054963710268 0.17240852551172 1.0 0.6487373759327787 14 Q9NQG6,Q8IWA4,Q9Y3D6,Q9NX63 4 +Peptidyl proline hydroxylation 0.5700234960985291 1.36363083916052 0.1726837810074744 1.0 0.64881078936074 8 O15460,P13674,O75718 3 +Regulation of insulin receptor signaling pathway 0.4873685150253443 1.3635341175213334 0.1727142395718224 1.0 0.64881078936074 15 P18031,Q9H1E3,Q96EB6,Q8TBX8,Q9HCD5,P05771 6 +Intraciliary transport involved in cilium assembly 0.7241577886553456 1.3624876336060814 0.1730440442301635 1.0 0.6493363177449898 4 Q9UPN4,A0AVF1,Q15154 3 +Regulation of steroid metabolic process 0.4871000770512109 1.3617691035621289 0.1732707650379761 1.0 0.6493363177449898 15 P34913 1 +Regulation of t cell differentiation in thymus 0.8330935251798548 1.3613743753948055 0.1733954097262613 1.0 0.6493363177449898 2 P00813 1 +Cation transmembrane transport 0.3015477716818927 1.3603664049053172 0.1737140041025284 1.0 0.6496036169305107 124 P21796,O75964,P06576,P00846,Q96ES6,P13073,Q13423,Q9Y619,O00400,P46934,Q15043,P30825,Q9HD20,Q8IYU8,Q96NB2,O43772,Q70HW3,P0DP25,Q8NEW0,P05067 20 +Microtubule depolymerization 0.4542462969995576 1.3595092356013831 0.1739852779150639 1.0 0.6500147966971196 20 P16949,Q9Y3E1,P25054,Q86Y91 4 +Regulation of lipid localization 0.4231018457378916 1.3590841826412532 0.1741199144286562 1.0 0.6500147966971196 25 P31751,Q9BZF3,P30536,Q8WTV0,Q9Y3D6,P31749 6 +Collagen metabolic process 0.5565422036730088 1.357157827402991 0.1747310675066951 1.0 0.6502132275990928 9 P08670 1 +Nucleoside catabolic process 0.7228341492243304 1.356843547815356 0.1748309272080015 1.0 0.6502132275990928 4 P00813 1 +Retina homeostasis 0.6722160714239934 1.356775847238338 0.1748524440735752 1.0 0.6502132275990928 5 P11166,Q15051 2 +Glycosphingolipid biosynthetic process 0.8319424460431641 1.3565686576667684 0.174918306164695 1.0 0.6502132275990928 2 Q16739 1 +Mitochondrial fragmentation involved in apoptotic process 0.6305961821190991 1.3564926334261354 0.1749424776391539 1.0 0.6502132275990928 6 Q8N163 1 +Triglyceride metabolic process 0.495394437033946 1.3563643060049797 0.1749832842674661 1.0 0.6502132275990928 13 Q8NCG7,Q96EB6,Q8WTV0,Q9HCL2 4 +Sulfur compound transport 0.4991833759013132 1.3552368024962085 0.1753421227233715 1.0 0.6502132275990928 12 P33527,Q70HW3 2 +Maternal process involved in female pregnancy 0.5435122785144391 1.354505355042097 0.175575206100371 1.0 0.6502895070238025 10 Q8IZL8,Q15363,P31749,Q9BQE5 4 +Regulation of smad protein signal transduction 0.8546229010541124 1.3527570494757153 0.1761332582340633 1.0 0.6510791534963407 3 P09874 1 +Regulation of nuclear cell cycle dna replication 0.853973036925616 1.3502394097927506 0.176939200606025 1.0 0.6516782519804915 3 O75844 1 +Heterochromatin organization 0.3794423037622598 1.349788389466307 0.1770838701736499 1.0 0.6517683915745537 38 Q9UPP1,Q8IXJ6,O95983,Q5T5X7,Q9UK61,Q96EB6,Q8NEY8 7 +Negative regulation of phosphatidylinositol 3 kinase signaling 0.7210828317577527 1.3493748782064732 0.1772165857221335 1.0 0.6517683915745537 4 Q10713 1 +Negative regulation of type i interferon mediated signaling pathway 0.6011745048096895 1.349070888804878 0.1773141977081525 1.0 0.6517683915745537 7 Q14166,Q7Z739,Q9Y3Z3,Q9Y5A9 4 +Pyrimidine containing compound transmembrane transport 0.8531765430265752 1.3471537448201962 0.1779307216844059 1.0 0.6525998611284329 3 Q99808 1 +Negative regulation of immune response 0.414920714600316 1.3443354166578123 0.1788399478001023 1.0 0.6525998611284329 27 Q14166,P28070,Q9Y5A9,Q7Z739,Q9UJ41,P04439,Q96FV9,Q86UT6,Q9Y3Z3,P46108,P09601,Q9Y4E8,P07948 13 +3 utr mediated mrna destabilization 0.6277856251363176 1.3430081025276088 0.1792693502265083 1.0 0.6525998611284329 6 Q92945,Q13148 2 +Caveolin mediated endocytosis 0.6689594125834329 1.341993041421483 0.179598251913267 1.0 0.6534361578445702 5 Q13432 1 +Glutamate receptor signaling pathway 0.7191657035332821 1.3411979600190975 0.1798561885413068 1.0 0.6536527447869116 4 Q8NCG7,P05067 2 +Positive regulation of glucose import 0.599512480198262 1.3407377992848395 0.1800055974764887 1.0 0.6536656490831007 7 P31751,P31749,Q16625 3 +Icosanoid transport 0.6685682672215001 1.3402171477768934 0.180174758261812 1.0 0.6536656490831007 5 P33527,P14174 2 +Regulation of water loss via skin 0.6270926076555932 1.3396821523556617 0.1803487024191561 1.0 0.6536656490831007 6 Q16739 1 +Epithelial cell proliferation 0.3592502749157547 1.33881033996099 0.1806324237921559 1.0 0.6542200048176375 46 Q9UII2,Q04721,Q6ZWJ1,Q15418,Q9P266,Q8WTV0,P09601,Q9H2J4,Q96EB6,P31749,O94788 11 +Negative regulation of leukocyte mediated immunity 0.6267738155253331 1.3381520694230933 0.1808468699496046 1.0 0.6542811637968601 6 P46108,Q9UJ41,P04439,P09601 4 +Positive regulation of cell death 0.2947258054003894 1.3377473012066936 0.1809788259544789 1.0 0.6542811637968601 129 Q7Z3C6,Q8IXJ6,Q8N163,Q9NS69,Q15257,Q13501,Q9NQX7,O95831,P98175,O94788,P25054,P30536,Q53EL6,Q07021,Q04721,Q9NR28,Q9Y3D6,P09601,Q96IZ0,P09874,P52756,Q13546,O14737,Q9NYF8 24 +Cellular response to copper ion 0.8267625899280564 1.334948599218568 0.1818931700701895 1.0 0.6552506807232104 2 P05067 1 +Neuron apoptotic process 0.3443914117477671 1.334663655005951 0.1819864540481826 1.0 0.6552506807232104 57 P31751,P09874,Q9NR28,Q99720,P51858,O95831,P05067,Q01105,P09601 9 +Negative regulation of catabolic process 0.3102184482941549 1.3333031391792998 0.1824323439420203 1.0 0.6553008178866645 113 O60506,Q9Y2W1,Q9Y2S7,P46379,Q8IXJ6,Q8N163,Q9H814,Q13148,P98175,Q14011,Q99729,Q13151,Q08J23,P30536,Q9H444,O15118,P31749,Q96HY6,Q9UL15,Q9NRR5,P67809,P35637,P09601,Q92804,Q16850,O43765,Q96JB5,Q92530,O95453,Q08379,Q9H2J4 31 +Superoxide metabolic process 0.5978679761910166 1.3324901078543812 0.1826991899126997 1.0 0.6553008178866645 7 P00374 1 +Negative regulation of cell population proliferation 0.3137400944872139 1.3304760092836223 0.1833614856738126 1.0 0.6553008178866645 108 Q8IXJ6,Q32P28,Q9NR77,P98175,Q92845,O94788,P25054,Q8IWX8,P30536,Q53EL6,P37198,Q15392,Q99627,P09601,Q01085,Q96IZ0,Q9UII2,P52756,Q9NPI1,O14737,Q96G23,P05067,Q96BK5 23 +Extrinsic apoptotic signaling pathway 0.3517900479139417 1.3288913102311832 0.1838838311528567 1.0 0.6553008178866645 51 P02545,Q13546,Q9NR28,Q99523,Q9HB09,P38398,Q9P0J0,P42575,P61289,Q9UGN5,Q8IWB1,Q9NQX7,P30154,Q9UER7,P31749,P09601 16 +Positive regulation of fibroblast migration 0.6245945574555101 1.3276903742305777 0.1842804147849825 1.0 0.6553008178866645 6 P31749 1 +Cell cycle phase transition 0.2943113406361154 1.3269580675644677 0.1845225540993422 1.0 0.6553008178866645 175 Q8IXJ6,P16104,Q96BK5,Q8N163,Q9ULX6,Q13123,Q9UJX3,P08183,P25054,Q9Y619,Q08J23,Q9UKG1,Q9H444,Q9UL46,Q9BXW9,P61289,P31749,Q96HY6,Q9NYL9,P48681,Q96EA4,Q9BVS4,O43823,Q96DY7,Q6Y7W6,Q8N7H5,O75312,Q9UPP1,Q6ZWJ1,P0DP25,Q96JB5,Q9NPI1,Q96RU2,P42575,O75663,Q07666,Q86Y37,P05067,P49321 39 +Lipoprotein metabolic process 0.4642449703103086 1.3268741700061744 0.184550310097451 1.0 0.6553008178866645 18 Q16739,Q9BQE5,Q9NUJ1 3 +Cellular nitrogen compound catabolic process 0.2965028914725713 1.3267967989083087 0.1845759096723134 1.0 0.6553008178866645 183 P51116,O60506,Q13126,Q9Y2W1,P30519,Q9Y5A9,Q9H814,Q9P2K5,Q13148,O95831,P98175,Q9H773,Q969T7,Q14011,Q99729,Q13151,Q08J23,P35610,P49902,Q02252,Q9BQG2,Q9Y3Z3,Q9BQ61,P00813,P31749,Q9NRN7,P67809,P08670,P35637,P52272,Q6Y7W6,P09601,Q92804,Q6PJT7,Q86VM9,Q92945,P51114,O75312,O95453,P62312,P33527,Q5RKV6 42 +Mitotic nuclear membrane organization 0.6244019901803446 1.3267657706270477 0.1845861766577097 1.0 0.6553008178866645 6 Q8IXJ6 1 +Organelle disassembly 0.3513219905688667 1.3233659784629606 0.1857137000361699 1.0 0.6578857900743675 51 Q9UII2,P21796,Q9Y4P1,Q9Y6I9,O00165,P30536,P27544,Q9Y3D6,Q13501,Q7KZI7,Q08379,Q7Z3C6 12 +Negative regulation of centrosome duplication 0.7148826845548759 1.32292635184715 0.1858598709430894 1.0 0.658049806364329 4 Q96PK6,Q92830 2 +Astrocyte development 0.6645581043726749 1.3220056940675562 0.1861662548383282 1.0 0.6584269743047477 5 P08670 1 +Positive regulation of histone modification 0.3657862113302076 1.321672800873331 0.1862771295514473 1.0 0.6584656687845959 43 O75150,P18615,Q9ULX6,P50750,P38398,Q03164,Q96EB6,Q5VTR2,P02545,Q13573,Q9GZS3,Q5UIP0,Q15020,Q06787,O43159,O43823,Q8N7H5,Q92830,Q9NPI1 19 +Negative regulation of glycoprotein metabolic process 0.8462867012089776 1.3204645746539951 0.1866799561055305 1.0 0.6589114296427033 3 Q9NY61,O14734 2 +Primary mirna processing 0.5953270772008402 1.319742171515517 0.186921114884945 1.0 0.6589114296427033 7 Q86U44,Q8WYQ5,Q9BXP5,P22626 4 +Negative regulation of histone acetylation 0.5951597741049309 1.318902609482728 0.1872016736629878 1.0 0.6589114296427033 7 Q96EB6,Q01105 2 +Protein targeting to membrane 0.3699192098517007 1.3152662874344734 0.1884204240665765 1.0 0.6617081652069406 41 P31751,O43765,P46379,Q9H444,P56589,O60725,O43681,P43307,Q9Y3D6,P40855,Q15629,Q9H9H4 12 +Collateral sprouting in absence of injury 0.821870503597121 1.314539775867799 0.1886646217501955 1.0 0.6617081652069406 2 P05067 1 +Protein depalmitoylation 0.6629105925910911 1.3145216826998485 0.1886707062683283 1.0 0.6617081652069406 5 Q9NUJ1,P50897 2 +Pteridine containing compound biosynthetic process 0.5942690049390283 1.3144321689559355 0.1887008108095069 1.0 0.6617081652069406 7 P31939,P00374 2 +Cartilage development 0.4687683729921128 1.3133753489941498 0.1890564998186192 1.0 0.6618986595668875 17 Q15043,O75844,Q92830,Q92896 4 +Regulation of protein folding 0.7123545706671532 1.3121392714291245 0.1894731475961066 1.0 0.6625913939557323 4 Q9UL15,O14737 2 +Connective tissue development 0.4076500170983665 1.3117071708801165 0.1896189563265489 1.0 0.6625913939557323 28 O75844,O15173,P35610,Q15043,Q92830,Q96EB6,Q96HY6,Q92896 8 +Pyrimidine containing compound catabolic process 0.5935763618712551 1.310955622392793 0.1898727570425051 1.0 0.6626438538946327 7 Q9H773 1 +Regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4880651474196321 1.3099236101412224 0.1902216790778754 1.0 0.662821972305732 13 P09874,P23246,Q96EB6,P31749,Q9UL15 5 +Lipid import into cell 0.5933397523906522 1.3097679368838355 0.1902743529727639 1.0 0.662821972305732 7 P31749 1 +Cellular response to xenobiotic stimulus 0.4168803129700744 1.3072117717983316 0.1911407986306021 1.0 0.6633564076641492 25 O43169,P07099 2 +Prenylation 0.6202684951105141 1.3069127300631802 0.1912423521487776 1.0 0.6633564076641492 6 P49354,Q7Z6K3,Q92696,P49356 4 +Negative regulation of nitric oxide metabolic process 0.6611429541470351 1.3064907479403842 0.191385723322135 1.0 0.6633564076641492 5 P30536 1 +Mating 0.6606423934916734 1.3042163264110105 0.1921598348041477 1.0 0.6639439703851755 5 P00813,P05067 2 +Histone phosphorylation 0.4164300365691462 1.303454014327366 0.1924198062025937 1.0 0.6641912444118494 25 O75844,O43823,P05771 3 +B cell homeostasis 0.5917932101855925 1.3020038826402582 0.192915058340213 1.0 0.6644377271094293 7 P00813 1 +Acute inflammatory response 0.6600529481699167 1.3015379180969835 0.1930743942253108 1.0 0.6644377271094293 5 P42785 1 +Negative regulation of t cell apoptotic process 0.8405296488197976 1.2981690909978127 0.1942292368151252 1.0 0.6672452770463297 3 P00813,Q99576 2 +Mitotic dna replication 0.5119102987508645 1.2972868370262909 0.1945325117286083 1.0 0.6673457182102499 11 Q14566,O75844 2 +Positive regulation of histone h3 k9 methylation 0.6586981566820327 1.2953813579143294 0.1951887057191066 1.0 0.6683893173375307 5 Q96EB6,P02545,P38398,Q5UIP0 4 +Negative regulation of defense response 0.3720693179511071 1.2939115015189575 0.1956959912406843 1.0 0.6683975569306364 39 Q14166,Q8IXJ6,P28070,Q9Y5A9,P04439,Q07021,P46108,Q9Y3Z3,P00813 9 +Peripheral nervous system axon regeneration 0.839188200626878 1.2929750684321528 0.196019682117112 1.0 0.6683975569306364 3 P30536 1 +Meiotic cell cycle 0.3304666824620809 1.2928899168898988 0.1960491353580071 1.0 0.6683975569306364 63 Q9UQ84,P16104,Q08J23,P46379,Q9Y5A9,Q8IXJ6,Q9H2V7,Q9BXW9,Q92791,Q08379,Q9UH99,Q9BTX1 12 +Viral transcription 0.4716469417405139 1.2926349592145063 0.1961373425799486 1.0 0.6683975569306364 16 Q00403,Q9H1E3,Q13148 3 +Neutral amino acid transport 0.6574454071677376 1.2896879706789397 0.1971590178871887 1.0 0.6693406132441997 5 Q96NB2 1 +Meiotic spindle assembly 0.6569848920959902 1.2875949406864522 0.1978870014137057 1.0 0.6703740114729599 5 Q08379 1 +Positive regulation of binding 0.3368722309440203 1.2806486673734756 0.2003170976259289 1.0 0.6727115601368546 59 Q00403,P16949,P09874,Q9Y2S7,Q8IXJ6,P41440,P0DP25,O60869,P35611,O75503,P05067,Q96HY6,Q96BK5 13 +Icosanoid metabolic process 0.4189722304313423 1.2805573826593717 0.2003491772140049 1.0 0.6727115601368546 23 Q15067,Q9H7Z7,P09960,P07099,P33527 5 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.4697830796059374 1.2800987620005777 0.2005104040162839 1.0 0.6727115601368546 16 P43246,O96028,Q96QE3,Q96FZ2,Q9UQ84,Q7KZ85,Q12888,Q96FV9,Q9NQT5,Q5RKV6,O60934,Q5UIP0 12 +Somatic diversification of immunoglobulins involved in immune response 0.4697830796059374 1.2800987620005773 0.2005104040162841 1.0 0.6727115601368546 16 P43246,O96028,Q96QE3,Q96FZ2,Q9UQ84,Q7KZ85,Q12888,Q96FV9,Q9NQT5,Q5RKV6,O60934,Q5UIP0 12 +Regulation of cell aging 0.4833037105613027 1.2797172618662784 0.2006445914517176 1.0 0.6727115601368546 13 P67809,O75844,P14174,Q96EB6,Q96IZ0 5 +Histone h3 k9 modification 0.4745932100710052 1.2794148462797246 0.2007510085425603 1.0 0.6727115601368546 15 P02545,Q03164,Q5T5X7,Q96EB6,Q8WTS6 5 +Histone h3 k4 dimethylation 0.8129496402877685 1.2773560479774837 0.2014765743879216 1.0 0.673503283105579 2 O15047 1 +Histone h3 k4 monomethylation 0.8129496402877685 1.2773560479774837 0.2014765743879216 1.0 0.673503283105579 2 O15047 1 +Positive regulation of lipid transport 0.613906808517273 1.276337026202469 0.201836406848912 1.0 0.673503283105579 6 P14174 1 +Iron ion homeostasis 0.4564851828581075 1.272155750072588 0.2033177862286113 1.0 0.6749394404357248 18 P09601,P30519,Q9Y5Y0 3 +Amino acid import 0.541015326059987 1.2719054248516608 0.2034067241574293 1.0 0.6749394404357248 9 P30825 1 +Mrna 3 end processing 0.3677627145873408 1.2700316681885226 0.2040733499245743 1.0 0.6749394404357248 40 Q5VTR2,O75150,Q6UN15,P18615,Q8N684,P50750,Q8N7H5,Q6PJT7,P05067 9 +Leptin mediated signaling pathway 0.8329250104616985 1.2687310096664273 0.2045370185692632 1.0 0.6752981561457182 3 Q16739 1 +Cellular response to leptin stimulus 0.702033767030223 1.2680930247852242 0.2047647321742391 1.0 0.6752981561457182 4 Q16739 1 +Response to leptin 0.702033767030223 1.2680930247852242 0.2047647321742391 1.0 0.6752981561457182 4 Q16739 1 +Gliogenesis 0.3374118004645129 1.2668672677016686 0.2052027544137538 1.0 0.6752981561457182 58 P08670,Q8IXJ6,P30536,Q96G23,P31749,P05067 6 +Cellular lipid metabolic process 0.3035035206194554 1.266700687734407 0.2052623340178843 1.0 0.6752981561457182 226 P37268,Q15118,Q6UWP7,Q8IXJ6,Q9NPH0,O15228,Q16134,O14734,Q8WTV0,P07099,Q8TBX8,Q8NCC3,P34913,Q9BY49,Q10713,O94788,O00116,Q9HBU6,Q8NBX0,O75521,Q15067,Q9HB40,Q96PU8,Q9NTG7,Q06136,P31749,Q8N4Q0,P31751,Q16739,Q9H7Z7,P23786,Q8NHP8,Q6NUM9,P35790,P50897,Q8IY17,P48449,Q13011,Q9NZC3,Q5T8D3,P14174,Q96G23,O75844,O95749 44 +Positive regulation of cell migration involved in sprouting angiogenesis 0.701475500882876 1.2657103363090172 0.2056168063615753 1.0 0.6753784332584345 4 P09601 1 +Positive regulation of transcription by rna polymerase ii 0.2925940901106567 1.2648380907640988 0.2059293737913452 1.0 0.6755189873702877 180 P53999,Q9Y2W1,P18615,Q8IXJ6,Q9H7B4,Q9ULX6,Q03164,P50750,P38398,Q8NCF5,P19338,P12956,P04150,Q13501,P51858,Q96EB6,Q92905,O00165,Q9HB09,Q9H1E3,Q92841,P38159,Q96PK6,P31749,Q96HY6,Q9NPJ6,P67809,P51812,P23246,Q9NY61,Q15418,Q92830,Q6PL18,P09874,Q13546,Q96JB5,Q96I24,Q8IZL8,P05067,Q9NYF8,P61978 41 +Purine containing compound transmembrane transport 0.5393733765095035 1.2628779492964206 0.2066330456394185 1.0 0.677042069025682 9 Q99808 1 +Mitophagy 0.4765595027940019 1.2628667755820395 0.2066370618926463 1.0 0.677042069025682 14 P21796,Q13501,Q9Y4P1 3 +Cellular response to radiation 0.3437674324873614 1.260092021094699 0.2076361682632643 1.0 0.677619966660054 53 P31751,P09874,P16104,O75844,Q96B01,Q96RU2,P38398,Q9H1E3,P27544,P12956,Q96EB6,Q14191,P46934 13 +Insulin like growth factor receptor signaling pathway 0.6996488710212128 1.25791430175857 0.2084227508440452 1.0 0.6788420688637737 4 P31749 1 +Glucose import 0.4709488269202622 1.2553815243356536 0.2093402930580463 1.0 0.6794508247738249 15 P31751,Q99523,Q9UKG1,Q16625,P11166,P31749 6 +Organic hydroxy compound biosynthetic process 0.3391775650745099 1.2515274771386526 0.2107420952998098 1.0 0.6816787756163214 56 P37268,O75845,Q16850,P00374,P48449,Q9BZF3,Q15392,O14734,Q9H4L5,P61457,Q96EB6 11 +Regulation of organic acid transport 0.525237593222093 1.2512100827340775 0.2108578405800913 1.0 0.6817185042111001 10 P31751,Q9Y3D6,P31749 3 +Regulation of protein localization to centrosome 0.6975193848484595 1.2488258970923591 0.2117287597647861 1.0 0.6838631363187136 4 P25054,P37198 2 +Positive regulation of cell differentiation 0.2909353600783398 1.246361966333687 0.212631537788217 1.0 0.6852453724790771 128 P55209,P09874,Q9UQB8,P51812,Q8IXJ6,Q15418,O00165,P30536,P12956,P46108,Q07021,Q9UGN5,Q8WUJ1,P00813,P31749,Q92830 16 +Myofibroblast differentiation 0.8269951913383702 1.245790002024816 0.212841501049275 1.0 0.685354436893025 3 P09874 1 +Neurotransmitter uptake 0.6074527588246985 1.2452970047849503 0.2130225962599659 1.0 0.685354436893025 6 Q99808 1 +Plasma membrane organization 0.369078778614664 1.2439834961510214 0.2135056370940111 1.0 0.6862383623475314 38 P31751,Q9UQB8,P41440,Q16739,Q9HD42,P31749 6 +L amino acid transport 0.5027309872067691 1.2428457501573118 0.2139246799096188 1.0 0.6872499833858988 11 P30825,Q9Y619 2 +Nucleoside triphosphate biosynthetic process 0.3749113114356237 1.24130778330424 0.214492070507374 1.0 0.6875338313698404 34 O75964,P09874,P06576,P00846,P55263,Q05682 6 +Positive regulation of mitochondrial membrane potential 0.6467448752948888 1.2410420520900716 0.2145902145660359 1.0 0.6875338313698404 5 P31749 1 +Atp biosynthetic process 0.438234011643102 1.2405878669331718 0.2147580363689623 1.0 0.6875805158576737 20 O75964,P00846,P06576,P09874 4 +Transepithelial transport 0.6062310491348042 1.239419539395597 0.215190169033995 1.0 0.6879611954221219 6 P08183 1 +Regulation of toll like receptor signaling pathway 0.5344999975167094 1.2360742130952975 0.2164309791282157 1.0 0.6893839689018 9 P41440,Q9UKG1,Q01804,Q9NQC3,P07948 5 +Carbohydrate transmembrane transport 0.4375762899522182 1.2356953803683153 0.2165718153671161 1.0 0.6893839689018 20 P31751,Q6ZWJ1,Q99523,Q16625,P31749,P05771 6 +Membrane disassembly 0.6054353946573454 1.2355915124816377 0.2166104411906184 1.0 0.6893839689018 6 P05771 1 +Negative regulation of transmembrane transport 0.4109050418574123 1.2349870823560083 0.2168353117408243 1.0 0.6893839689018 24 P31751,P21796,P31749,P46934,P05771 5 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.6450716822370687 1.2334340857137875 0.217413854511753 1.0 0.6893839689018 5 O15460 1 +Response to uv 0.3469052890841416 1.2313944539266115 0.2181753702542463 1.0 0.6911334204832834 47 P09874,Q14011,Q9BRK5,Q8N163,Q96RU2,P46934 6 +Peroxisome fission 0.6442018100956463 1.2294787556578666 0.2188923582320452 1.0 0.6930714792844527 5 P40855,O14734 2 +Glycolipid biosynthetic process 0.5331600888804022 1.228702496964338 0.2191833696807168 1.0 0.6935378538236365 9 Q8NBX0 1 +Amide transport 0.3547497979351943 1.228524423196443 0.2192501668712452 1.0 0.6935378538236365 44 P08183,O00233,O00400,P41440,Q8N183,P53985,P33527,P00367 8 +Isoprenoid biosynthetic process 0.4784481443368267 1.2260352167998814 0.2201854227155923 1.0 0.6936955016880307 12 P48449,Q86YH6,Q5T2R2,O95749,O94788 5 +Dna conformation change 0.280622364136169 1.225335448857713 0.2204488573206264 1.0 0.6936955016880307 147 Q8IXJ6,P16104,Q9H7B4,Q9ULX6,Q7Z5K2,P12956,O94761,Q9UK61,O95831,Q96EB6,P22626,P33991,Q04837,Q9BRT9,Q8WXX5,Q9HD42,Q01105,Q2NKX8,P55209,Q5T5X7,O95983,O43823,Q8N7H5,Q9UER7,Q8NEY8,Q9UPP1,Q99733,Q14566,Q9NRG0,Q14191,P49321 31 +Cellular response to dexamethasone stimulus 0.6031805422036172 1.224742091665123 0.2206724095837997 1.0 0.6936955016880307 6 Q9H7B4 1 +Exit from mitosis 0.478144692716936 1.2241416329153023 0.2208988028637968 1.0 0.6936955016880307 12 Q8IXJ6 1 +Labyrinthine layer blood vessel development 0.603008515227161 1.2239143169882103 0.2209845521023274 1.0 0.6936955016880307 6 P31749 1 +Regulation of muscle organ development 0.5321646531495438 1.22322544701706 0.2212445567642169 1.0 0.6936955016880307 9 Q8IXJ6 1 +Regulation of mitophagy 0.6028080909516256 1.2229498892644688 0.2213486236850601 1.0 0.6936955016880307 6 P21796 1 +Cellular response to insulin stimulus 0.3354257755804887 1.2227990046797002 0.2214056214979403 1.0 0.6936955016880307 57 P31751,P09874,Q9UQB8,P25054,Q6ZWJ1,Q15043,Q9UKG1,Q9HCD5,Q8TBX8,Q96A49,Q96EB6,P31749,Q9BSK2,P05771 14 +Regulation of immune response 0.2824787870562951 1.220335877705615 0.2223375743397599 1.0 0.6943591527988952 134 P43246,Q9NW08,P46379,P28070,Q8TCT8,Q9Y5A9,P12956,P04439,Q96FV9,Q86UT6,Q96EB6,O60828,P07948,Q9NUQ9,P41440,Q7Z739,Q9UKG1,Q07021,Q9Y3Z3,P00813,Q96PK6,Q5UIP0,Q86U44,P51812,P23246,Q9UJ41,Q01804,Q14671,Q12888,Q7Z434,P09601,P43243,Q15233,Q96IZ0,Q9Y4E8,Q96RT1,O96028,Q14166,P18031,Q96EP0,P46108,Q8WXF1,Q07666,Q5RKV6,Q9NZ08,P05771 46 +Cardiac septum morphogenesis 0.5754928956578886 1.2200860834715324 0.2224322435431343 1.0 0.6943591527988952 7 O96028 1 +Regulation of synaptic plasticity 0.3817706922102689 1.2200390973315942 0.2224500539857385 1.0 0.6943591527988952 32 Q96A49,P05067,Q9UQB8,Q92830 4 +Cholesterol efflux 0.5425577841887819 1.2168640772128 0.2236559353046527 1.0 0.6943591527988952 8 P35610,Q96EB6,Q8WTV0 3 +Import into cell 0.3931100107835691 1.2150727580588605 0.2243383426089265 1.0 0.6943591527988952 29 P31751,P41440,Q99808,P30825,P31749 5 +Purine deoxyribonucleoside monophosphate metabolic process 0.8189225456841884 1.2145845634029404 0.224524579323956 1.0 0.6943591527988952 3 P55263 1 +Damp metabolic process 0.8189225456841884 1.2145845634029404 0.224524579323956 1.0 0.6943591527988952 3 P55263 1 +Maintenance of protein location in mitochondrion 0.689403672351651 1.2141943870867289 0.2246735033794573 1.0 0.6943591527988952 4 P30536 1 +Regulation of glucose import 0.4764992690853115 1.213873164063529 0.2247961620306076 1.0 0.6944125230284451 12 P31751,P31749 2 +Neurotransmitter metabolic process 0.6891059117824783 1.2129240304584257 0.2251588671500544 1.0 0.6945402116335317 4 P21964 1 +Multicellular organismal response to stress 0.541772631224134 1.212661843634974 0.2252591337472844 1.0 0.6945402116335317 8 P30536 1 +Lymphocyte apoptotic process 0.4413271305763602 1.2113806165374903 0.225749564707858 1.0 0.6950818523639872 19 P24390,Q13546,Q9HCL2,Q99576,P14174,Q96EY1,P00813,P31749 8 +Negative regulation of secretion 0.410297557145717 1.2101663417847957 0.2262150705902024 1.0 0.6955348110680558 23 Q16850,O00233,Q8N183,P09601,P00813 5 +Positive regulation of calcium mediated signaling 0.8170755449515019 1.207449776811107 0.2272589756348781 1.0 0.6964694839340523 3 P00813 1 +Positive regulation of phosphatidylinositol 3 kinase signaling 0.572734337778237 1.2062122594903728 0.2277356581174201 1.0 0.6971199270761766 7 P22681,O00165,P46934 3 +Neuronal stem cell population maintenance 0.5992924457777219 1.2060316022305402 0.2278053055080851 1.0 0.6971199270761766 6 Q9BXP5,Q9BXW9,Q15154 3 +Double strand break repair via break induced replication 0.5171711961942153 1.2055353317575332 0.2279967069196531 1.0 0.6971199270761766 10 P33991,Q14566,Q9BRT9 3 +I kappab phosphorylation 0.6870895439486111 1.2043220989984464 0.2284651084262348 1.0 0.6971199270761766 4 P31749,Q96HY6 2 +Negative regulation of mast cell degranulation 0.7948201438848906 1.2019687745058514 0.2293756263319397 1.0 0.6971199270761766 2 P09601 1 +Negative regulation of myeloid leukocyte mediated immunity 0.7948201438848906 1.2019687745058514 0.2293756263319397 1.0 0.6971199270761766 2 P09601 1 +Negative regulation of leukocyte degranulation 0.7948201438848906 1.2019687745058514 0.2293756263319397 1.0 0.6971199270761766 2 P09601 1 +Negative regulation of mast cell activation involved in immune response 0.7948201438848906 1.2019687745058514 0.2293756263319397 1.0 0.6971199270761766 2 P09601 1 +Negative regulation of mast cell activation 0.7948201438848906 1.2019687745058514 0.2293756263319397 1.0 0.6971199270761766 2 P09601 1 +Negative regulation of cell aging 0.5983050792271052 1.2012797823778745 0.2296426902567545 1.0 0.6972390087523549 6 P67809,P14174 2 +Response to growth factor 0.2905772820136805 1.19996243728552 0.2301539290828826 1.0 0.6979758200216232 126 Q8NEM2,Q8IXJ6,Q99523,P04150,P33240,Q96EB6,Q92896,O00400,O95429,Q9UKG1,Q9P266,Q53EL6,P22681,Q96A49,P31749,P46934,Q9UQB8,Q04721,Q9Y2U8,Q92830,O75312,P09874,Q13546,Q8N0X7,O14737,P46108,P05067,P05771 28 +Macroautophagy 0.3037546483992059 1.199426490117275 0.230362152336544 1.0 0.6979758200216232 111 P21796,Q9Y2S7,Q99816,Q93050,P16615,O00189,Q8TBX8,Q9NV70,Q13501,Q96EB6,Q9Y3E7,Q9H9H4,O15269,Q8NCE2,Q9Y6I9,Q9H444,P27544,O15118,O43464,O14964,Q9HD42,P36543,P31749,Q96HY6,Q9P275,P46934,Q6UWE0,Q9NRR5,Q9Y679,Q9Y4P1,Q9NZZ3,P09601,O95721,Q9UPT5,O14681,Q96HS1,Q9UNZ2,Q96EP0,Q9Y263,Q9UI12,Q5T8D3,Q9Y5K8,Q7Z3C6 43 +Entry of bacterium into host cell 0.6858623668298429 1.1990874918751706 0.2304939272025712 1.0 0.6979758200216232 4 P22681,Q9UPT5,Q9BTY2 3 +G protein coupled receptor signaling pathway 0.3433848519462752 1.1990598171039213 0.230504687261656 1.0 0.6979758200216232 48 P0DP25,Q99523,Q15043,Q99720,P42892,Q9BYT8,P00813,P31749 8 +Hepatocyte growth factor receptor signaling pathway 0.5975704775400739 1.1977443597978368 0.2310165541161681 1.0 0.6985706988177977 6 Q8IXJ6 1 +Lens development in camera type eye 0.6370924779426719 1.197153475581555 0.2312467399106923 1.0 0.6985706988177977 5 P28289,P08670 2 +Regulation of chromosome segregation 0.3430375866103234 1.195046828764616 0.2320687344205798 1.0 0.6991773621843623 48 P25054,Q8IXJ6,Q96SB8,Q7Z5K2,Q13123,Q96EA4,Q9UJX3,Q9NS91,Q9BVS4 9 +Response to thyroglobulin triiodothyronine 0.792805755395682 1.193611371017564 0.2326300238836269 1.0 0.6995888760242894 2 P16278 1 +Negative regulation of centriole replication 0.8126079447322915 1.1902006070055575 0.233967554679626 1.0 0.7007328262654801 3 Q96PK6,Q92830 2 +Copi coated vesicle budding 0.6350146129295848 1.1877067928793803 0.2349489466082723 1.0 0.7022418991486524 5 Q8N6H7 1 +Regulation of transcription regulatory region dna binding 0.4717181728310453 1.1840306213790088 0.2364009415581267 1.0 0.7035893014180662 12 P09874,O75844 2 +Heme transport 0.8109369207915127 1.1837522863279246 0.2365111347118782 1.0 0.7035893014180662 3 Q9Y5Y0 1 +Iron coordination entity transport 0.8109369207915127 1.1837522863279246 0.2365111347118782 1.0 0.7035893014180662 3 Q9Y5Y0 1 +Purine ribonucleoside salvage 0.634012834584254 1.183152678303653 0.2367486435683656 1.0 0.7036250845611013 5 P55263 1 +Nucleoside salvage 0.634012834584254 1.183152678303653 0.2367486435683656 1.0 0.7036250845611013 5 P55263 1 +Regulation of mast cell activation involved in immune response 0.6815358017224672 1.180636486938577 0.2377471624113964 1.0 0.7051191592900764 4 P09601,Q9UJ41 2 +Regulation of mast cell activation 0.6815358017224672 1.180636486938577 0.2377471624113964 1.0 0.7051191592900764 4 P09601,Q9UJ41 2 +Cellular component disassembly involved in execution phase of apoptosis 0.5357713114914648 1.1805376941599857 0.237786427673782 1.0 0.7051191592900764 8 Q96JB5,O95831 2 +L alpha amino acid transmembrane transport 0.5126140641713878 1.1797209542712723 0.2381112169911383 1.0 0.7056760109639098 10 P30825,Q9Y619 2 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.8097294185377015 1.1790938834815965 0.2383607939101635 1.0 0.7056760109639098 3 O75844,Q96HY6 2 +Regulation of histone h3 k9 trimethylation 0.633099274777574 1.178999814178222 0.2383982498270653 1.0 0.7056760109639098 5 Q9NWS0,Q96EB6,P02545 3 +Regulation of amyloid beta clearance 0.6330381397061429 1.1787219136382878 0.2385089267618383 1.0 0.7056760109639098 5 Q16850,P04035 2 +Somatic diversification of immunoglobulins 0.4064063255654453 1.1785647828614765 0.2385715218623532 1.0 0.7056760109639098 23 P43246,O96028,Q9UQ84,Q96FZ2,Q7KZ85,Q12888,O60318,Q96FV9,Q9NQT5,Q9Y3Z3,Q5UIP0,Q5RKV6,O60934,Q96QE3 14 +Mrna metabolic process 0.3096153754665106 1.1765753872796605 0.2393650263554638 1.0 0.7057644199525969 384 O75150,O75940,P18615,Q9P2K5,Q86V81,Q5VTR2,P98179,Q14011,O75400,Q92841,Q9BQG2,P38159,Q96PK6,P31942,Q96I25,P23246,P08670,P35637,P52272,P55081,Q8IZ73,Q92804,Q6PJT7,Q15233,P52597,O75312,Q8N684,O95453,P62312,P31943,Q15427,P05067,P51116,Q8N163,Q9ULX6,P50750,P33240,P19338,Q8IY67,Q969T7,O60828,P22626,Q99729,Q9Y2W2,Q9UPR3,Q5T200,Q15459,O95391,P62310,P62995,Q6P2P2,Q96ST2,P31749,O75475,Q16637,Q6UN15,Q6I9Y2,Q96E39,P78332,O75525,Q01130,Q9BZI7,Q92945,Q86UA1,P51114,Q15637,P52756,Q13242,Q9BXP5,Q9BWF3,Q96DF8,P51991,O95400,Q07666,Q15424,Q5RKV6,P61978,P52948,O60506,Q07955,Q9UHX1,Q9Y5A9,O43390,Q13123,Q9UBB9,P98175,Q53R41,Q13595,Q14320,Q08J23,Q7Z739,Q96PU8,P09651,O75934,Q07021,Q53F19,Q9Y3B4,Q96RS0,Q99590,Q15717,Q15020,Q06787,Q9H0D6,O60508,O75494,Q14103,Q9P013,Q12874,Q6Y7W6,Q86U42,Q8WXF0,Q12849,Q8WWY3,Q92917,P38432,O43290,A2RRP1,Q15007,Q9Y2W1,Q8NC51,Q14562,Q13464,P07910,Q96FV9,Q13148,Q96MU7,Q6NZY4,Q13573,Q13151,Q13868,Q8IWZ8,P67809,Q8N7H5,Q96EP5 134 +Regulation of leukocyte migration 0.3727800674132601 1.1759534777359195 0.2396134670839775 1.0 0.7057644199525969 33 P00813,P46108,Q07021,P09601,Q00013,P31749,P05067 7 +Regulation of mitochondrial gene expression 0.4660948401125208 1.1703985437143505 0.2418406214484743 1.0 0.709414649166171 13 Q07021,Q567V2,Q9Y2R0 3 +Regulation of notch signaling pathway 0.5334882641793991 1.1683159443474576 0.2426793462288805 1.0 0.710131849581315 8 Q9Y5A9,P31749 2 +Outer mitochondrial membrane organization 0.6307136635730294 1.1681563668843316 0.2427436970861967 1.0 0.710131849581315 5 Q9NS69,O14737 2 +Cellular response to peptide 0.3122928309792079 1.166316861296063 0.2434863584368067 1.0 0.711770903167755 83 P31751,P09874,Q9UQB8,P25054,P08670,Q6ZWJ1,Q15043,Q9UKG1,P31749,P46108,Q9HCD5,Q8TBX8,Q96A49,Q96EB6,P33527,P05067,Q9BSK2,P05771 18 +Regulation of lipid metabolic process 0.3226361746986545 1.1642093939416025 0.2443391642200503 1.0 0.7136306529458827 62 P31751,P30536,Q9NTG7,Q8WTV0,Q96G23,O75844,P31749,P34913 8 +Associative learning 0.4611908286879099 1.1633824706625835 0.2446743584289548 1.0 0.7140253549888865 14 P05067,P50897 2 +Response to ketone 0.3553832644376715 1.1613559996610094 0.2454971547811473 1.0 0.714901163449135 41 P09874,Q13126,P0DP25,Q9H7B4,P30536,P04150,O43823,O95831,P31749,P49321 10 +Deoxyribonucleoside triphosphate metabolic process 0.5208787392798173 1.1611106480333433 0.2455969050377868 1.0 0.714901163449135 9 P55263,P00813,Q9H773 3 +Carbohydrate derivative catabolic process 0.3640463167563329 1.1605195595218474 0.2458373349379563 1.0 0.714901163449135 36 P49902,Q9NUJ1,O60502,P00813,Q9H773 5 +Allantoin metabolic process 0.8047596774019736 1.159932809966458 0.2460761631055756 1.0 0.714901163449135 3 P49902 1 +Positive regulation of cell aging 0.6285793287776099 1.1584566071784608 0.2466777499341115 1.0 0.715346567614239 5 Q96EB6,Q96IZ0 2 +Positive regulation of lipid catabolic process 0.6279538232748307 1.155614233280858 0.2478389835035399 1.0 0.7171765754522725 5 P31751,Q8NCG7,P50416 3 +B cell apoptotic process 0.530995051504284 1.1549693651422412 0.2481029718452903 1.0 0.7173104350542421 8 P00813 1 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4874736228769294 1.152259634142575 0.2492143989945254 1.0 0.7186556800016541 11 Q96RU2,P14174,P46379,P61978 4 +Establishment of protein localization to membrane 0.3096736188266618 1.1519174258532017 0.2493550067648631 1.0 0.7187227207233958 93 P46379,Q9NS69,O60725,Q9P0J0,O75608,Q9H9H4,Q15070,Q4J6C6,Q9H444,O43681,O15118,P31751,Q9Y3D6,Q9HD20,P98194,O43765,P0DP25,P56589,O14737,P43307,Q9Y512,P40855,Q15629 23 +Regulation of autophagy of mitochondrion 0.4505355056151991 1.1504858191776188 0.249943831590242 1.0 0.720104900021034 16 P21796,O00165,P30536 3 +Negative regulation of notch signaling pathway 0.6740403769906835 1.1486916225060146 0.250683161494361 1.0 0.720573605496929 4 P31749 1 +Cell maturation 0.3890419648479105 1.1484988759116506 0.2507626767953343 1.0 0.720573605496929 28 Q9Y5A9,P05067,Q8IXJ6,Q9Y5Y0 4 +Response to inorganic substance 0.2992146401023928 1.1473614628204027 0.251232261441406 1.0 0.7208388409983755 113 P09874,P00374,P0DP25,Q99720,P30536,P31939,Q9UBV8,O60888,P09960,O95831,P31749,P05067,Q96IZ0,P46934,P09601 15 +Regulation of glucose transmembrane transport 0.4446557293665804 1.1472154656699325 0.251292581237406 1.0 0.7208388409983755 17 P31751,P31749,Q16625,P05771 4 +Endomembrane system organization 0.2888515539454615 1.1466193154107145 0.2515389899645748 1.0 0.7212159046965265 188 P46379,Q8IXJ6,Q9ULX6,Q8TBA6,Q86XL3,Q13501,Q13148,Q12768,P20700,Q9H9H4,P02545,P41440,Q9H444,O43681,Q9P253,Q9HD42,Q8NHH9,P31749,Q9UL15,P31751,Q15363,Q9UQB8,Q96ED9,O15260,Q14108,Q16739,Q9Y2U8,Q5SQN1,O95721,Q8N1F7,Q9BTU6,O43765,Q08379,Q15629,Q9UH99,O75844,Q9P2W9,Q7Z3C6,P05771 39 +Positive regulation of epithelial cell migration 0.3648285430452732 1.1424136794832105 0.2532821078232787 1.0 0.7220438238492458 34 P09601,Q8WTV0,P31749,P06576 4 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4492631355608122 1.1419142016935313 0.2534896848634969 1.0 0.7220438238492458 16 O95831,Q9NR28 2 +Regulation of gtp binding 0.5595300660439166 1.1397946248671562 0.2543718736221545 1.0 0.7222232292008146 7 P16949,O75503 2 +Negative regulation of gene expression epigenetic 0.3619674383449276 1.139693365101854 0.2544140723303545 1.0 0.7222232292008146 36 Q9UPP1,Q8IXJ6,O95983,Q5T5X7,Q9UK61,Q8NEY8 6 +Glycerolipid biosynthetic process 0.3313507385904775 1.138704161104111 0.254826566604821 1.0 0.7222232292008146 55 Q6UWP7,Q9BTU6,Q9HBU6,Q9NPH0,O15228,P42356,Q8WTV0,Q8TBX8,Q8NCC3,P35790,Q10713 11 +Glycerophospholipid metabolic process 0.3128674827380327 1.1383990332198262 0.2549538975749119 1.0 0.7222232292008146 66 Q8IY17,Q6UWP7,Q9BTU6,Q9HBU6,Q9NPH0,O15228,Q9NZC3,P42356,Q8WTV0,Q8TBX8,Q8NCC3,P35790,Q10713 13 +Viral budding 0.452781630606411 1.135463758533365 0.2561810584771169 1.0 0.72414285470001 15 Q99816,Q9H9H4,Q9H444,Q9HD42,Q9Y3E7,P46934,Q6UWE0 7 +Regulation of response to oxidative stress 0.4089783652368323 1.1334600896741844 0.2570210921479554 1.0 0.7255008607393886 22 P09874,P23246,P00374,Q13546,Q96EB6,P31749,Q96IZ0,Q9UL15 8 +Ubiquitin dependent endocytosis 0.7775539568345307 1.130492214298252 0.2582688772752368 1.0 0.7268701678484045 2 Q6UWE0 1 +Lipid catabolic process 0.3097095374473706 1.1291451862862842 0.2588365922526832 1.0 0.7275914276249699 78 P31751,Q8IY17,Q8IXJ6,Q13011,O75521,Q16134,Q15067,P23786,O14734,Q8WTV0,Q8NHP8,Q8NCC3,P31749,P50897 14 +Deoxyribose phosphate metabolic process 0.4558284819397212 1.1286614713069745 0.2590406683876169 1.0 0.7278545688724982 14 P55263,Q9H773 2 +Lipoprotein catabolic process 0.5827015919407131 1.1261915141069838 0.2600844646198814 1.0 0.7295430129333328 6 Q9NUJ1,P50897 2 +Regulation of translation initiation in response to endoplasmic reticulum stress 0.7761151079136674 1.124553839034933 0.2607781439008834 1.0 0.730245299686749 2 Q15363 1 +Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation 0.7761151079136674 1.124553839034933 0.2607781439008834 1.0 0.730245299686749 2 Q15363 1 +Anatomical structure maturation 0.3571262757883903 1.121655459873213 0.2620089611550396 1.0 0.7321361514209312 38 Q8IXJ6,Q08J23,Q9Y5A9,Q9Y5Y0,P05067,O94788 6 +Regulation of defense response 0.3027616823897083 1.1210751131847958 0.2622558909984898 1.0 0.7322950063617714 105 Q8IXJ6,P28070,Q9Y5A9,P12956,P04439,Q86UT6,Q9UKG1,Q53EL6,Q9BXW9,Q07021,Q9Y3Z3,Q96PK6,P00813,Q6UWE0,P23246,P43243,Q14166,Q13546,P46108,Q8WXF1,O75844,P33527,P05067,Q9NZ08 24 +Mitochondrial fission 0.4583202083526935 1.1209904691495196 0.2622919193449657 1.0 0.7322950063617714 13 O60313,Q9NUQ9,Q9UDX5,O00429,Q9Y3D6,Q9NQG6 6 +Activation of innate immune response 0.4221309787128263 1.120738409798737 0.2623992275034363 1.0 0.7322950063617714 20 P23246,Q8WXF1,Q7Z434,P12956,P43243,Q96PK6,Q15233,O60828 8 +Positive regulation of mitochondrial calcium ion concentration 0.5814181647561415 1.1200177015548565 0.2627062188498574 1.0 0.7324607850452459 6 Q9Y3D6 1 +Phosphatidic acid metabolic process 0.5241664178101507 1.1184209212426317 0.2633872631234508 1.0 0.7325470965864832 8 O15228,Q6UWP7,Q9NPH0 3 +Establishment of protein localization to mitochondrial membrane 0.4403939250297688 1.1178284949460942 0.2636402490069769 1.0 0.7325470965864832 17 P0DP25,O14737,Q9NS69,Q9P0J0,Q9Y512 5 +Ubiquinone metabolic process 0.5551282958413654 1.1176593561841284 0.263712507679942 1.0 0.7325470965864832 7 Q5T2R2,Q9Y5Z9,Q9Y2Z9 3 +Import across plasma membrane 0.4144534912279967 1.116721659928115 0.2641133537211648 1.0 0.7326458038699138 21 P31751,P30825,P31749,P41440 4 +Response to ionizing radiation 0.3420642816677425 1.1157127285229 0.2645451203712863 1.0 0.7326458038699138 45 P09874,P16104,O75844,Q96B01,Q96RU2,Q9H1E3,Q9BXW9,P12956,P22681,Q70UQ0,Q96EB6,Q14191 12 +Response to aldosterone 0.7932154527925142 1.1155061289676234 0.2646335934980168 1.0 0.7326458038699138 3 O95831 1 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.4496782127161118 1.1149782578115044 0.2648597389322593 1.0 0.7326458038699138 15 Q9HD42,Q9H444,P46934 3 +Mitochondrial depolarization 0.5803164001508773 1.1147182997507692 0.2649711565673098 1.0 0.7326458038699138 6 P09874,P30536 2 +Ensheathment of neurons 0.3705378969290049 1.114096018250858 0.2652379966548239 1.0 0.7326912538262379 32 P31751,Q8IXJ6,Q96PU8,Q9NR77,P31749 5 +Adaptive immune response 0.3393010184300052 1.1134275054155849 0.2655248673621804 1.0 0.7326912538262379 46 O96028,Q9UQ84,Q07021,P00813,Q5RKV6,Q9NZ08,P05771 7 +Positive regulation of phosphoprotein phosphatase activity 0.6177671988028177 1.1093517583534398 0.2672784648956785 1.0 0.7362449018384724 5 Q15257 1 +Defense response to gram positive bacterium 0.6636219512502134 1.10434772343224 0.26944232839059 1.0 0.7404040605690692 4 Q96JM3 1 +Positive regulation of peptidyl serine phosphorylation 0.4199152698689675 1.1042478639702509 0.2694856319855598 1.0 0.7404040605690692 20 O95429,Q9H7B4,O00165,P14174,P31749,P05067 6 +Cellular response to gamma radiation 0.4792207861710624 1.103262957121557 0.2699129881267332 1.0 0.7405743672561589 11 O75844,P16104 2 +Positive regulation of amyloid precursor protein biosynthetic process 0.7898922651222785 1.1027417997288729 0.2701393089624941 1.0 0.740709626162763 3 Q96IZ0 1 +Toll like receptor signaling pathway 0.4476983772766331 1.1019122356605031 0.2704998286513109 1.0 0.7410907987457329 15 Q01804,P51812,P41440 3 +Amino acid transport 0.4320791818126338 1.0997520135939796 0.2714401853868924 1.0 0.7424322878846966 18 P30825,Q9Y619,Q96NB2 3 +Protein insertion into er membrane 0.4548376519978135 1.098866640799642 0.2718262392681934 1.0 0.7428714601983103 13 O43765,P46379,O43681,Q15629,Q8N4V1 5 +Positive regulation of gene expression 0.2974637085187637 1.0964806197013903 0.2728685000295436 1.0 0.7435570833638486 238 P51116,O60506,Q9Y2W1,Q9Y5A9,P38398,P19338,P04439,Q9Y2R0,Q13148,Q96EB6,P98175,P34913,O60828,Q567V2,O94788,Q13595,P98179,Q14011,Q99729,P02545,P41440,Q13151,Q9UKG1,Q96PU8,Q71RC2,P82970,P62995,Q07021,Q52LJ0,P38159,P31749,Q96HY6,Q15363,P67809,P08670,P35637,Q16625,Q96E39,Q96AE4,P09601,Q92804,Q92830,Q96IZ0,P51114,O96028,O75312,Q9UPP1,Q13546,Q9NWS8,Q96EP5,Q07666,O14737,O75787,Q15427,Q96I24,Q5RKV6,P14174,Q9H2J4,O75844,P05067 60 +Maternal placenta development 0.5763019611261357 1.0954141073863568 0.2733352563996174 1.0 0.7435581757502713 6 Q15363,P31749 2 +Histone h3 k9 acetylation 0.6615116008213222 1.0953759500141829 0.2733519659843983 1.0 0.7435581757502713 4 Q03164,P38398 2 +Regulation of acyl coa biosynthetic process 0.7689208633093507 1.0949103435532623 0.2735559170653947 1.0 0.7435581757502713 2 Q15118 1 +Hypoxia inducible factor 1alpha signaling pathway 0.7689208633093507 1.0949103435532623 0.2735559170653947 1.0 0.7435581757502713 2 Q15118 1 +Mitochondrial protein processing 0.5756408048805309 1.092235657979742 0.2747295330672237 1.0 0.7438746792434785 6 Q9Y4W6,Q99797,Q10713 3 +Negative regulation of immune system process 0.3249527124709806 1.0918637533417102 0.2748929916824933 1.0 0.7438746792434785 57 Q14166,P28070,Q9Y5A9,Q9UKG1,P04439,Q99576,Q86UT6,Q9Y3Z3,P46108,P14174,P09601,P00813,P31749,Q96IZ0 14 +Regulation of toll like receptor 4 signaling pathway 0.6603972532934194 1.0906401442280114 0.2754312579247915 1.0 0.7438746792434785 4 Q9UKG1,P41440 2 +Toll like receptor 4 signaling pathway 0.6603972532934194 1.0906401442280114 0.2754312579247915 1.0 0.7438746792434785 4 Q9UKG1,P41440 2 +Peripheral nervous system myelin maintenance 0.6602683490225094 1.09009239649863 0.2756724453142691 1.0 0.7438746792434785 4 P31749 1 +Regulation of mitochondrion organization 0.3330369538679141 1.0875528646330477 0.2767925488189726 1.0 0.7448756380312311 49 Q9UII2,P21796,O60313,P02545,Q9NUQ9,O00165,P30536,P27544,O14737,Q9Y3D6,O43464,Q13501,Q9NQG6,P31749 14 +Positive regulation of membrane depolarization 0.6595849409114696 1.0871886847134529 0.2769534304812273 1.0 0.7448756380312311 4 P30536 1 +Cell cycle g2 m phase transition 0.3256865560693735 1.0844849401373882 0.2781498407161282 1.0 0.7448756380312311 56 P08183,Q6NUQ1,Q9Y619,P0DP25,Q96JB5,Q9ULX6,P38398,P48681,P05067,O43823,Q9HAW4,Q07666,Q15058,Q96BK5 14 +Response to sodium arsenite 0.7660431654676241 1.0830770175653257 0.2787742391000871 1.0 0.7448756380312311 2 Q9UER7 1 +Cellular response to sodium arsenite 0.7660431654676241 1.0830770175653257 0.2787742391000871 1.0 0.7448756380312311 2 Q9UER7 1 +Cellular response to salt 0.7660431654676241 1.0830770175653257 0.2787742391000871 1.0 0.7448756380312311 2 Q9UER7 1 +Mitotic cell cycle phase transition 0.2716510774477317 1.0805247201804262 0.2799085848154237 1.0 0.7448756380312311 142 Q8IXJ6,Q96BK5,P38398,Q13123,Q06323,Q9UJX3,P08183,P25054,Q9Y619,Q9UKG1,Q9H444,Q9UL46,P61289,P31749,Q15058,Q6NUQ1,Q9NYL9,P48681,Q96EA4,Q9BVS4,Q96DY7,Q6Y7W6,O75312,Q9UPP1,P0DP25,Q96JB5,Q9NPI1,P42575,Q9UJX2,Q9HAW4,Q07666,Q86Y37,P05067,P49321 34 +Snrna transport 0.6110701946170899 1.0789744970701982 0.2805990967087588 1.0 0.7448756380312311 5 Q9H814 1 +Tail anchored membrane protein insertion into er membrane 0.4946399796033406 1.0779258475229787 0.2810668494088348 1.0 0.7448756380312311 10 O43681,O43765,Q8N4V1,P46379 4 +Positive regulation of protein acetylation 0.4478769053787728 1.0772010370449503 0.2813904620911907 1.0 0.7448756380312311 14 Q9NPI1,Q92830,P38398 3 +Negative regulation of peptidyl lysine acetylation 0.5051091323272537 1.0743490157928843 0.282666284122234 1.0 0.7448756380312311 9 Q96EB6,Q01105 2 +Positive regulation of autophagy 0.3805697164820634 1.074114086874036 0.2827715516433557 1.0 0.7448756380312311 28 O15269,P21796,O00443,Q13464,Q96EP0,P27544,Q8TBX8,O95817,P09601,P08754,Q96EB6,Q86UE4,Q6UWE0 13 +Pore complex assembly 0.4502359682808743 1.0696479092754076 0.2847778215969518 1.0 0.7448756380312311 13 P49790,P52948,Q9NQC3,P57740,P12270,Q9BTX1,Q8N1F7 7 +Response to wounding 0.3054452602463225 1.0694719961101598 0.2848570408921471 1.0 0.7448756380312311 87 Q96AY3,P00374,P30536,Q16625,P46108,Q8WTV0,Q9HD42,Q96G23,P42785,P09601 10 +Regulation of translation in response to stress 0.4733336911817537 1.0683355173105504 0.2853691926706438 1.0 0.7448756380312311 11 Q15418,Q15363,Q9BWF3,P51812 4 +Oocyte differentiation 0.4531497067318461 1.068162744853324 0.2854471066973529 1.0 0.7448756380312311 12 Q8IXJ6 1 +Regulation of rig i signaling pathway 0.503597942614149 1.0660423811285782 0.2864044840815691 1.0 0.7461732502468233 9 Q07021,Q86UT6,Q9Y4E8 3 +Glial cell migration 0.4527755663182766 1.0658304923876083 0.2865002742193896 1.0 0.7461732502468233 12 P30536 1 +Lysine metabolic process 0.6542395799007896 1.0644933460102428 0.2871052671381191 1.0 0.747426552814329 4 Q9BQT8 1 +Bleb assembly 0.6536135905557321 1.0618375387459995 0.2883094448889003 1.0 0.7487863351883974 4 Q13464,Q4KMQ2,Q9NR77 3 +Positive regulation of phosphatase activity 0.5692267628978077 1.0614160967617534 0.2885008448020021 1.0 0.7489882058315177 6 Q15257,Q8IV63,P0DP25 3 +Tetrahydrobiopterin metabolic process 0.7788965460747095 1.060599711757552 0.2888718536186827 1.0 0.7490659754008266 3 P00374 1 +Negative regulation of voltage gated calcium channel activity 0.759999999999998 1.058275826847097 0.2899297102308202 1.0 0.7502899097373955 2 P0DP25 1 +Dna methylation dependent heterochromatin assembly 0.4479669631953978 1.0552488938093665 0.2913115078263277 1.0 0.7515471907077814 13 Q9UK61,O95983,Q8NEY8 3 +Intracellular lipid transport 0.4707746625503646 1.053163084793633 0.292266254087159 1.0 0.7528312541752504 11 P23786 1 +Response to gamma radiation 0.4192663733594124 1.051522968812758 0.2930184659183745 1.0 0.7536745269374037 19 P09874,P16104,Q9BXW9,P12956,O75844 5 +Folate transmembrane transport 0.7582733812949621 1.051202597295115 0.2931655505449333 1.0 0.7536745269374037 2 P41440 1 +Folic acid transport 0.7582733812949621 1.051202597295115 0.2931655505449333 1.0 0.7536745269374037 2 P41440 1 +Sphingoid metabolic process 0.6038616361215958 1.046322220613794 0.2954122896019551 1.0 0.7553246318150105 5 Q06136 1 +Regulation of protein deacetylation 0.4390598421637641 1.0449441694964643 0.2960487739401956 1.0 0.7554130602272056 15 Q8N163,Q9ULX6,O43823 3 +Histone h3 k9 methylation 0.4428477375962147 1.044684940759815 0.2961686071365415 1.0 0.7554130602272056 14 Q5T5X7,Q96EB6,Q8WTS6,P02545 4 +Cellular response to lipid 0.2950894024953121 1.0435533034663116 0.2966921071609347 1.0 0.7554130602272056 110 Q9H7B4,P04150,Q9P0J0,Q8WTV0,Q96JM3,Q96JN0,O95831,Q96EB6,O94788,P30536,Q53EL6,Q92841,O15118,Q9P253,P31749,Q96HY6,P46934,P08670,O15173,O43823,Q8N7H5,P09874,P14174 23 +Positive regulation of mitophagy 0.6492299169072252 1.043252420951907 0.2968314007353736 1.0 0.7554130602272056 4 P21796 1 +Regulation of autophagy 0.2998679809945493 1.0431049487500723 0.2968996889677835 1.0 0.7554130602272056 101 P21796,Q9Y2S7,Q8IXJ6,Q93050,Q8TBX8,Q9NV70,Q96EB6,O15269,O00165,P30536,Q9H444,P27544,O15118,O43464,P31749,Q86UE4,P46934,Q6UWE0,Q9NRR5,P09601,Q96EP0,Q9Y5K8,Q08379,O75844 24 +Inner mitochondrial membrane organization 0.4116884796022683 1.0430590810514064 0.2969209305298868 1.0 0.7554130602272056 20 O60313,Q5XKP0,O75431,Q9NX63,Q9P0J0,Q9Y512,Q13505,Q16891 8 +Response to insulin 0.3017012428779893 1.0426442890073864 0.297113068964415 1.0 0.7555685107705638 68 P31751,P09874,Q9UQB8,P25054,Q6ZWJ1,Q99523,Q15043,Q9UKG1,Q9HCD5,Q8TBX8,Q96A49,Q96EB6,P31749,Q9BSK2,P05771 15 +Protoporphyrinogen ix metabolic process 0.6022288378567537 1.038933971945653 0.2988354454629909 1.0 0.755682088572583 5 P22830 1 +Proton transporting two sector atpase complex assembly 0.6018764405444236 1.0373398221354166 0.2995775130939495 1.0 0.755682088572583 5 Q15070,Q5TC12 2 +Diacylglycerol biosynthetic process 0.7726781933628428 1.0368380998978246 0.299811316015899 1.0 0.755682088572583 3 Q8NCC3 1 +Ribonucleoside monophosphate metabolic process 0.3697089225099341 1.03634099581413 0.3000430868572834 1.0 0.755682088572583 30 P31939,P49902,P55263,P00813,Q05682 5 +Positive regulation of protein localization to centrosome 0.772069845859801 1.0345165042879625 0.3008947651974578 1.0 0.755682088572583 3 P37198 1 +Positive regulation of glucose metabolic process 0.5083306971429472 1.0337675935966597 0.3012448248232726 1.0 0.755682088572583 8 P31751,P31749,Q92830 3 +Positive regulation of cellular carbohydrate metabolic process 0.5083306971429472 1.0337675935966597 0.3012448248232726 1.0 0.755682088572583 8 P31751,P31749,Q92830 3 +Response to bmp 0.4167186805240637 1.0330870724639465 0.3015631525688933 1.0 0.755682088572583 19 Q04721,O00400,Q8N0X7,Q53EL6,Q9Y2U8,Q14318 6 +Synaptonemal complex organization 0.5382403665783722 1.032837568332193 0.3016799193410586 1.0 0.755682088572583 7 Q92791 1 +Phosphatidylglycerol metabolic process 0.4469267175220529 1.0293943217317063 0.3032944163168238 1.0 0.7566856906897207 12 Q6UWP7 1 +Reactive nitrogen species metabolic process 0.4214362320324654 1.0246415292149325 0.3055323615378778 1.0 0.7604241417386852 18 O43169,P30536,P31749 3 +Pancreas development 0.4396708134997195 1.02416288073728 0.3057583480168513 1.0 0.7604241417386852 14 O94788 1 +Regulation of t cell receptor signaling pathway 0.5063641028044127 1.023271748090515 0.306179377713458 1.0 0.7604241417386852 8 P00813 1 +Liver morphogenesis 0.6444537148878173 1.0230310478850917 0.3062931662125467 1.0 0.7604241417386852 4 Q15418 1 +Negative regulation of neuron death 0.3359963255520489 1.022064181218043 0.3067505246634785 1.0 0.7607973544143458 44 O95630,Q9UMX5,Q9H444,P48681,P22681,Q9UGN5,P51858,P09601,P50897,Q96EB6,P31749,Q15233,Q01105 13 +Actin crosslink formation 0.644222172029983 1.022051542020806 0.306756506396854 1.0 0.7607973544143458 4 Q9UQB8 1 +Chromatin assembly or disassembly 0.3021726341681301 1.0203653089824782 0.3075552401594248 1.0 0.7607973544143458 87 P55209,Q9UPP1,Q8IXJ6,P16104,Q9H7B4,Q8WXX5,Q969G3,Q5T5X7,Q99733,O95983,Q9UK61,Q8N7H5,Q96EB6,Q9UER7,Q01105,P49321,Q8NEY8 17 +Signal release 0.3132615262535908 1.0190579304208258 0.3081754650071162 1.0 0.7607973544143458 61 Q4J6C6,O00233,Q6ZWJ1,P0DP25,Q8N183,P53985,Q6WKZ4,P14174,Q5SQN1,O95721,P50897,P00367,P05771 13 +Specification of symmetry 0.4947720252415789 1.0175760485362375 0.3088794746179937 1.0 0.7617054307668495 9 Q15363,O94788 2 +Purine deoxyribonucleoside triphosphate metabolic process 0.6424710977242375 1.014646397318934 0.3102744140937425 1.0 0.7617054307668495 4 P55263,P00813 2 +Lymphocyte homeostasis 0.4344494889073172 1.0145822577983603 0.3103050002730425 1.0 0.7617054307668495 15 Q9HCL2,Q99576,P14174,P00813,P31749 5 +Adult locomotory behavior 0.4301593621170398 1.013364840777195 0.3108859267291677 1.0 0.7617054307668495 16 P28289,O75844,P05067,P50897 4 +Negative regulation by host of viral transcription 0.6419419502549302 1.0124095628259482 0.3113422679190289 1.0 0.7619769868009421 4 Q13148 1 +Negative regulation of amyloid beta clearance 0.7660864406303187 1.011713166680997 0.3116752182148459 1.0 0.7622104792466473 3 Q16850 1 +Cell recognition 0.3855579734997221 1.009312636113376 0.3128247219024798 1.0 0.7634057323729377 23 Q8WTV0,P05067,P45880 3 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.3499830101424508 1.00749774510511 0.3136956407751772 1.0 0.7644011009865542 35 O96028,P00813,Q5RKV6,Q9UQ84 4 +Suckling behavior 0.6405397582976095 1.0064841976205652 0.3141827094146316 1.0 0.7650221257697738 4 P05067 1 +Positive regulation of toll like receptor signaling pathway 0.5946360849673332 1.0046218482998523 0.3150789727342684 1.0 0.765071376401712 5 Q9NQC3,P41440 2 +Positive regulation of protein neddylation 0.7467625899280557 1.004208013833136 0.3152783602059683 1.0 0.765145162208886 2 Q92564 1 +Regulated exocytosis 0.344026656961215 1.0037079681724164 0.3155193952272079 1.0 0.7654481940913378 39 Q4J6C6,Q06787,Q5SQN1,Q9BRK5,P0DP25,Q9UJ41,O14795,P16615,O14936,O43760,P22681,Q6WKZ4,Q14160,Q9P253,P09601,O95721,P07948,P05771 18 +Negative regulation of protein secretion 0.44202842468177 0.9989215036047836 0.3178327184204741 1.0 0.7686503086226861 12 Q16850,Q8N183,O00233 3 +Negative regulation of telomere maintenance via telomere lengthening 0.4615993537125028 0.9988340649699724 0.317875081086846 1.0 0.7686503086226861 11 P09874,Q9H0A0,P09651,Q9NVN8,Q96BK5 5 +Cellular response to acid chemical 0.4354854593096664 0.9971540087471596 0.3186897608732182 1.0 0.7700208413618023 14 Q9UQB8 1 +Cell proliferation in forebrain 0.5921903083122478 0.993586497560375 0.3204242204437255 1.0 0.7717083505776385 5 Q9UIS9,Q15058,Q15154 3 +Glycerolipid metabolic process 0.2999667269776854 0.9935494607007812 0.3204422593990619 1.0 0.7717083505776385 75 Q8IY17,Q6UWP7,Q9BTU6,Q9HBU6,Q9NPH0,O15228,Q9NZC3,P42356,Q8WTV0,Q8TBX8,Q8NCC3,Q96EB6,P35790,Q10713 14 +Placenta blood vessel development 0.4899270605351423 0.9910146879635632 0.3216784082344048 1.0 0.7735808755334842 9 Q15363,P31749 2 +Extraembryonic membrane development 0.7433093525179836 0.9901684619003652 0.3220917849620779 1.0 0.7737013383576855 2 Q15363 1 +Chorion development 0.7433093525179836 0.9901684619003652 0.3220917849620779 1.0 0.7737013383576855 2 Q15363 1 +Dsrna processing 0.3830789264300819 0.9892298941468288 0.3225506753897831 1.0 0.7741895900225799 23 Q86U44,O00571,Q13546,Q9BXP5,Q14671,Q9UGR2,O75376,Q8WYQ5,O75844,P22626 10 +Positive regulation of histone h4 acetylation 0.6362949341293505 0.9885653245665388 0.3228758586787685 1.0 0.7741895900225799 4 P38398 1 +Dna templated transcription termination 0.4997981847240799 0.9882682712119109 0.3230212801947443 1.0 0.7741895900225799 8 O75844 1 +Pyridine containing compound catabolic process 0.7597349040283671 0.9875720159156094 0.3233622970619305 1.0 0.7741895900225799 3 Q9BQG2 1 +Response to tumor cell 0.5908441231385917 0.9875164581035848 0.3233895186673265 1.0 0.7741895900225799 5 Q04721 1 +Alcohol metabolic process 0.2996982420352757 0.9869183127891205 0.3236826859243173 1.0 0.7741895900225799 89 P37268,Q16850,O75845,Q9BQE5,P00374,P48449,P61457,Q9NZC3,Q15392,P48735,P30837,P05067,Q8WTV0,Q9BY49,Q6NUM9,P34913,Q10713,O94788 18 +Nuclear body organization 0.5906618663818466 0.9866948728513923 0.3237922443159915 1.0 0.7741895900225799 5 Q15637,O75312,Q9BPY3 3 +Positive regulation of isotype switching to iga isotypes 0.7424460431654656 0.9866631309930576 0.3238078101312935 1.0 0.7741895900225799 2 O96028 1 +Intrinsic apoptotic signaling pathway in response to dna damage 0.3752048453254183 0.9790492936603802 0.327555623962652 1.0 0.7756252911086657 26 P46379,Q8N163,Q96RU2,P42575,P14174,P09601,Q96EB6,P61978 8 +Ribonucleoside triphosphate biosynthetic process 0.3666152025221824 0.9785786435689292 0.3277882158047238 1.0 0.7756252911086657 29 O75964,P09874,P06576,P00846,Q05682 5 +Regulation of nervous system development 0.2969840357376617 0.9762229974717608 0.3289539691147825 1.0 0.7756252911086657 68 P55209,Q9UQB8,Q8IXJ6,P30536,Q96G23,P31749 6 +Mitochondrial membrane organization 0.3232887635894683 0.9740402263426624 0.3300365663884212 1.0 0.7756252911086657 49 Q9UII2,Q15070,P0DP25,Q5XKP0,O75431,Q3ZCQ8,Q9NX63,Q9NS69,P45880,Q9P0J0,O14737,Q9Y512,Q13505,Q8IWA4,Q16891 15 +G quadruplex dna unwinding 0.5877583375555557 0.9736136352874908 0.3302484135416847 1.0 0.7756252911086657 5 P22626 1 +Positive regulation of mitotic nuclear division 0.4350520883010561 0.9734485119570394 0.3303304382008527 1.0 0.7756252911086657 13 P37198 1 +Autophagosome membrane docking 0.7389928057553937 0.9726606751896544 0.3307219759549882 1.0 0.7756252911086657 2 O95721 1 +Regulation of bmp signaling pathway 0.4345408458758967 0.9702174874487516 0.3319380957895208 1.0 0.7756252911086657 13 Q9Y2U8,Q04721,Q8N0X7 3 +Regulation of long term synaptic potentiation 0.4861168854243867 0.9701540854571208 0.3319696931532845 1.0 0.7756252911086657 9 P05067 1 +Response to abiotic stimulus 0.2922124608125047 0.9698161715932824 0.3321381305410178 1.0 0.7756252911086657 243 P30519,Q8IXJ6,P16104,P22830,P00846,Q8N163,P12956,O95831,P55786,P08183,Q14011,Q9BRK5,Q99808,P30536,O95391,P00813,P31749,P46934,P31751,Q70UQ0,P09601,P09874,Q96RU2,O75844,P05067 25 +Positive regulation of interferon gamma production 0.6317304923697187 0.9693311179752396 0.3323800080793027 1.0 0.7756252911086657 4 P04439,Q14160,Q9NUQ9 3 +Regulation of guanyl nucleotide exchange factor activity 0.6316953198437157 0.9691830480259656 0.3324538675167681 1.0 0.7756252911086657 4 P16949 1 +Regulation of sulfur metabolic process 0.7544617156016058 0.9675850196843482 0.33325166172843 1.0 0.7756252911086657 3 Q15118,Q15120 2 +Iron ion transmembrane transport 0.7544617156016052 0.967585019684346 0.3332516617284311 1.0 0.7756252911086657 3 Q15043,Q8N4V1 2 +Negative regulation of production of molecular mediator of immune response 0.736978417266185 0.964506908730064 0.3347918463614547 1.0 0.777181297126682 2 P09601 1 +Somite development 0.4303763604920128 0.9642355671070704 0.334927836358694 1.0 0.777181297126682 14 Q92830,O94788 2 +Response to estrogen 0.4302784308069945 0.963605228350806 0.3352438845679324 1.0 0.777181297126682 14 Q8IZL8,P21266,P38398,P09601 4 +Regulation of endothelial cell migration 0.3506695111869816 0.9634223310074398 0.3353356241813867 1.0 0.777181297126682 33 P06576,Q8WTV0,P09601,P31749,P42785 5 +Histone h3 k14 acetylation 0.5241091516940445 0.9620965393375148 0.3360011123262034 1.0 0.7773872721156012 7 Q96EB6,Q92830 2 +Regulation of skeletal muscle cell differentiation 0.6300050587803248 0.9620700637654132 0.3360144105304647 1.0 0.7773872721156012 4 Q9BYT8 1 +Negative regulation of innate immune response 0.4217869405481877 0.9572157705341028 0.3384583586690888 1.0 0.7805747725833483 16 Q14166,Q9Y5A9,P46108,P04439,Q9Y3Z3 5 +Meiotic spindle organization 0.4936954413317941 0.955799071141048 0.3391737577135432 1.0 0.7808268781789658 8 Q08379 1 +Microtubule anchoring at microtubule organizing center 0.5837163715937078 0.955427985097274 0.3393613074364201 1.0 0.7808268781789658 5 Q8TD16,Q15154 2 +Negative regulation of toll like receptor signaling pathway 0.7338129496402855 0.9517159924194 0.3412410365327771 1.0 0.7808268781789658 2 Q01804 1 +Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules 0.7498863209380473 0.950286882802448 0.3419665021329718 1.0 0.7810482515221427 3 Q92845 1 +Cytokine production involved in inflammatory response 0.5214177981131244 0.948659743456512 0.3427936947676562 1.0 0.7813063257629754 7 Q9UKG1,Q53EL6 2 +Extrinsic apoptotic signaling pathway via death domain receptors 0.3989427606330972 0.948506872796558 0.3428714756525175 1.0 0.7813063257629754 20 Q9NR28,Q99523,Q8IWB1,P09601,Q9UER7 5 +Hematopoietic stem cell homeostasis 0.626475778783251 0.9472357616782808 0.3435186562050902 1.0 0.7813063257629754 4 Q14157 1 +Adult behavior 0.3984776365263259 0.945064988307875 0.3446256984965683 1.0 0.7824452560828148 20 P28289,O75844,P05067,P50897 4 +Nucleoside phosphate catabolic process 0.404498883976341 0.9448569477911936 0.3447319135541677 1.0 0.7824452560828148 19 Q9BQG2,Q9H773,P49902 3 +Smooth muscle cell apoptotic process 0.4909696348777341 0.9413205979756232 0.3465405901993119 1.0 0.7833931402367517 8 Q96EB6,P98175,Q53EL6 3 +Mrna alternative polyadenylation 0.5803727817592246 0.9404078139203408 0.3470084156448991 1.0 0.7841009776009055 5 Q8N684,Q16630,Q96MU7 3 +Imp metabolic process 0.4323621120578493 0.9389395788058136 0.3477617669541391 1.0 0.7841796245267268 12 P31939 1 +Positive regulation of peptidyl lysine acetylation 0.451422970127361 0.9387610567321628 0.3478534374831792 1.0 0.7841796245267268 11 Q9NPI1,Q92830 2 +Cellular response to estrogen stimulus 0.5799443447883407 0.9384847919010988 0.3479953288990969 1.0 0.7841796245267268 5 Q8IZL8,Q9H6U6,O15164 3 +Lipid metabolic process 0.2978614661894585 0.9367328274636746 0.3488960056848662 1.0 0.7850377297993362 298 P37268,Q15118,Q6UWP7,Q8IXJ6,Q9BZF3,Q9NPH0,P06576,O15228,Q16134,O14734,P42356,O75608,P07099,Q8WTV0,Q9H6V9,Q8TBX8,Q8NCC3,Q96EB6,P34913,Q9BY49,Q10713,O94788,Q9BQE5,O00116,Q9HBU6,Q8NBX0,P35610,O75521,P30536,Q9HCL2,Q9HB40,Q96PU8,Q15067,Q9NTG7,P21964,O15118,O43681,Q9H4L5,P27544,Q06136,P31749,Q8N4Q0,P31751,O75845,Q16739,Q15392,Q9H7Z7,P23786,Q9UHB6,Q8NHP8,Q6NUM9,P35790,P50897,Q9BTU6,Q16850,Q8IY17,O15254,P48449,Q13011,O60869,Q9NZC3,P49356,P53985,Q5T8D3,P09960,P46108,P14174,Q96G23,O75844,P05067,O95749 71 +Autophagosome maturation 0.4086618551422672 0.9347845182460032 0.3498993597064204 1.0 0.7860507606906253 18 Q9HD42,O95721,Q9H444 3 +Positive regulation of viral life cycle 0.5173231660332704 0.9282441509844038 0.3532809369943717 1.0 0.788637805616653 7 P52292,Q99816,Q9H9H4 3 +Feeding behavior 0.4884740419378408 0.9280794796680704 0.353366343129186 1.0 0.788637805616653 8 P05067,Q6Y7W6 2 +Positive regulation of erad pathway 0.6218451025832428 0.9278105350052372 0.3535058582966486 1.0 0.788637805616653 4 O43765 1 +Leukotriene metabolic process 0.541248130410625 0.9275233859455784 0.3536548554356851 1.0 0.788637805616653 6 P09960 1 +Regulation of lipid biosynthetic process 0.3506258952676335 0.9265489535396146 0.3541607689657788 1.0 0.788637805616653 32 Q9NTG7,P30536,Q8WTV0 3 +Membrane protein intracellular domain proteolysis 0.7429156223791054 0.924017599907431 0.3554771525002369 1.0 0.788637805616653 3 Q8TCT9 1 +Hippo signaling 0.5163850901158398 0.9235719099713936 0.355709244483132 1.0 0.788637805616653 7 Q01085 1 +Reactive oxygen species metabolic process 0.3269876194848418 0.923093966559869 0.3559582385648696 1.0 0.788637805616653 44 Q9UII2,Q13423,O75489,P00374,Q8IXJ6,Q9NY61,P30536,Q15067,Q9P0J0,P42785,Q9BSK2 11 +Leukotriene transport 0.7419854709330536 0.9205204639416724 0.3573008441498269 1.0 0.7905491142052415 3 P33527 1 +Myotube differentiation 0.4065603430817787 0.9200489506009282 0.3575471795618214 1.0 0.7908285888327766 18 P41440,Q99523,Q9H7B4,Q8NEZ5,Q9BYT8 5 +Multi multicellular organism process 0.3655618832656393 0.9187779074138788 0.358211750322531 1.0 0.7913521250140746 27 Q15363,Q9BQE5,P41440,Q7Z7E8,Q9UIQ6,Q07021,Q8IZL8,P31749 8 +Interferon gamma production 0.5152023386364777 0.9176837970266132 0.3587844328849265 1.0 0.7915244631428747 7 P04439,Q07021 2 +Regulation of neurotransmitter transport 0.4158636758134237 0.9176104946831126 0.3588228215826023 1.0 0.7915244631428747 16 Q4J6C6,P05771,P0DP25 3 +Sterol biosynthetic process 0.3651888391980692 0.9155764983031044 0.3598890625183997 1.0 0.793345276993555 27 P37268,Q15392,Q16850,P48449 4 +Regulation of cell cycle phase transition 0.265504782707187 0.9153426148710466 0.360011793937675 1.0 0.7933504047676725 135 Q8IXJ6,P16104,Q8N163,P38398,Q13123,Q06323,Q9UJX3,P25054,Q9Y619,Q08J23,Q9UKG1,Q9UL46,Q9BXW9,P61289,P31749,Q15058,Q96HY6,Q6NUQ1,Q9NYL9,Q96EA4,Q9BVS4,Q8N7H5,Q96DY7,Q6Y7W6,Q6ZWJ1,Q96JB5,Q9NPI1,Q96RU2,P42575,Q9UJX2,O75663,Q9HAW4,P05067,Q96BK5 34 +Fibroblast proliferation 0.4056567045406509 0.9137177420955016 0.360865178862197 1.0 0.7941014874910729 18 Q96IZ0,O75844,P14174 3 +Cell activation involved in immune response 0.3337090219834523 0.91365578699996 0.3608977428416473 1.0 0.7941014874910729 40 O96028,Q9UQ84,P05067,P22681,P09601,P00813,Q5RKV6 7 +Dicarboxylic acid catabolic process 0.5381979088897393 0.913005392877574 0.3612397052392353 1.0 0.7941970029433839 6 P00367,O14734 2 +Astrocyte differentiation 0.4469448904926403 0.912408303744268 0.3615538199228494 1.0 0.7942183969521803 11 P08670 1 +Delamination 0.7240287769784151 0.9123627154205964 0.3615778099117022 1.0 0.7942183969521803 2 Q9Y5A9 1 +Regulation of neuronal synaptic plasticity 0.4755204505770968 0.9122995572832135 0.3616110473298741 1.0 0.7942183969521803 9 P05067 1 +Peptidyl lysine modification 0.2876191502356079 0.9096738922247368 0.3629945167430652 1.0 0.7959304062629142 109 Q96AY3,P18615,P46379,Q8IXJ6,Q9H7B4,Q03164,P49366,P38398,O60318,Q86U70,Q96EB6,Q8WTS6,Q00403,P02545,Q9BU89,Q9NTG7,Q86UY6,Q01105,Q5T5X7,O95983,Q92791,O95619,Q92830,O15047,O96028,Q14166,Q9NPI1,O75844 28 +Golgi vesicle budding 0.5130718120045087 0.9070854516377378 0.3643616108383267 1.0 0.7962704267044339 7 Q8N6H7 1 +Atrial septum morphogenesis 0.7382279720167071 0.9064137721364532 0.3647168859702576 1.0 0.7962704267044339 3 O96028 1 +Cardiac atrium development 0.7382279720167071 0.9064137721364532 0.3647168859702576 1.0 0.7962704267044339 3 O96028 1 +Atrial septum development 0.7382279720167071 0.9064137721364532 0.3647168859702576 1.0 0.7962704267044339 3 O96028 1 +Cardiac atrium morphogenesis 0.7382279720167071 0.9064137721364532 0.3647168859702576 1.0 0.7962704267044339 3 O96028 1 +Cellular response to carbohydrate stimulus 0.3614062085095363 0.906333861521274 0.3647591679337081 1.0 0.7962704267044339 28 Q99808,Q8N183,Q15043,P62995,P05771 5 +Regulation of neutrophil chemotaxis 0.5129198313952053 0.9063298304712258 0.3647613009068329 1.0 0.7962704267044339 7 Q07021 1 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4640019658150683 0.9052140458984952 0.3653520021182683 1.0 0.7963295871509328 10 Q8N163,P14174,P61978 3 +Neuron maturation 0.4839558014134245 0.9041453812522214 0.3659183174807487 1.0 0.7964158367264651 8 P05067 1 +Isotype switching to iga isotypes 0.7371905584340726 0.9025249803807824 0.3667780576818766 1.0 0.7968020514559463 3 P43246,O96028 2 +Positive regulation of smooth muscle cell apoptotic process 0.5718058254302527 0.9020310184480154 0.3670403905814803 1.0 0.7971091409167349 5 P98175 1 +Positive regulation of peptidyl threonine phosphorylation 0.4832973580659693 0.9006619328366432 0.367768094497833 1.0 0.7972193144115448 8 P05067 1 +Negative regulation of organelle assembly 0.4631753835675646 0.9005824029195734 0.3678103942729174 1.0 0.7972193144115448 10 Q96PK6,Q92830,Q9H444 3 +Neurotransmitter secretion 0.3792526474581524 0.899912977747649 0.3681665631825617 1.0 0.7972193144115448 22 Q4J6C6,P0DP25,Q5SQN1,O95721,P50897,P05771 6 +Regulation of actin cytoskeleton reorganization 0.4447294142475827 0.8993927866211371 0.3684434800340586 1.0 0.7972193144115448 11 O00165,Q9UQB8 2 +Protein trimerization 0.6149519032512648 0.8989825247170701 0.3686619689252741 1.0 0.7972193144115448 4 Q99720 1 +Positive regulation of cell activation 0.3247040601001306 0.8980704470127954 0.3691479933631238 1.0 0.7972193144115448 44 O96028,Q15418,P30825,P49366,P12956,P00813,P31749 7 +Positive regulation of dna dependent dna replication 0.534431408252745 0.8951066417048267 0.3707300838829972 1.0 0.7977147258736331 6 O95785 1 +Recombinational repair 0.2951214755866698 0.8945334828527867 0.3710365233013855 1.0 0.7977361339907413 66 P33991,Q9NRR5,P09874,P23246,P16104,Q96B01,Q9BRT9,Q96SB8,P35637,P38398,Q9H1E3,Q7Z4V5,Q14566,O94761,Q9Y3Z3,O95619,Q14191 17 +Peptidyl serine modification 0.2936072543695285 0.8937689806828428 0.3714455090428887 1.0 0.7977361339907413 79 P31751,P09874,P51812,Q15418,O00165,Q9UGN5,P31749,P05067,P05771 9 +Regulation of transcription by glucose 0.7191366906474796 0.8927971623766416 0.3719658062371151 1.0 0.7978511079260913 2 Q96EB6 1 +Multicellular organism growth 0.3432188565763207 0.8920863286099996 0.3723466621448976 1.0 0.7978511079260913 33 Q15363,Q04721,P05067,Q6Y7W6,Q9Y5Y0,O75844,Q92830 7 +Positive regulation of muscle cell differentiation 0.4715448703457945 0.8906670249642502 0.3731078301330965 1.0 0.7989624610812393 9 Q96EB6,Q92830,Q9UGN5 3 +Protein acetylation 0.2983472263008961 0.8888901903824106 0.3740620979571005 1.0 0.7998926585351351 64 Q00403,P46379,O75844,Q03164,Q9NPI1,P38398,O95983,Q5T5X7,O60318,Q86U70,Q01105,Q9NYB0,Q96ST2,Q86UY6,Q96EB6,O95619,Q92830,Q5VZE5 18 +Alcohol biosynthetic process 0.3343101807104932 0.8885023123187333 0.3742706125760846 1.0 0.7998926585351351 38 P37268,Q16850,P00374,P48449,Q15392,P61457 6 +Regulation of long term synaptic depression 0.7179856115107892 0.8882049561090296 0.3744305133302461 1.0 0.7999355665376936 2 Q06787 1 +Negative regulation of immune effector process 0.4427128141995365 0.8875595419466272 0.37477772459353 1.0 0.7999399927612086 11 P46108,P04439,Q9UKG1,P09601 4 +Leukocyte homeostasis 0.4017772476591434 0.8865740942081299 0.3753082463474222 1.0 0.8001064564560486 18 Q9HCL2,Q99576,P14174,P00813,P31749 5 +Positive regulation of response to dna damage stimulus 0.3236426490177301 0.886450983889821 0.3753745561180639 1.0 0.8001064564560486 44 P51116,P51114,P09874,P16104,Q96B01,Q8N163,P35637,Q7Z4V5,Q96EB6,O95619,Q9NYF8 11 +Cellular response to corticosteroid stimulus 0.4235841320938273 0.8847064028673413 0.3763150014429779 1.0 0.8011436331204463 12 Q9H7B4,O95831 2 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.4702749262214669 0.8837665487566776 0.3768222475117246 1.0 0.8017054532950448 9 O43681,O43765,Q9H444 3 +Positive regulation of membrane potential 0.5078423715380587 0.8811188254280732 0.3782535089558356 1.0 0.8019484548212397 7 P31749 1 +Regulation of secondary metabolic process 0.7159712230215804 0.8801794255776234 0.3787621173780084 1.0 0.8019484548212397 2 Q9UKG1 1 +Dendritic cell apoptotic process 0.7159712230215804 0.8801794255776234 0.3787621173780084 1.0 0.8019484548212397 2 P07948 1 +Collateral sprouting 0.6102765652598067 0.8794955587924203 0.3791326401022372 1.0 0.8022173942304563 4 P05067 1 +Response to metal ion 0.2920816887442936 0.8792655183927662 0.379257327342652 1.0 0.8022236050917285 67 Q9UJS0,P09874,P0DP25,P30536,Q9UBV8,O60888,P09960,P09601,P31749,P05067,P46934 11 +Response to retinoic acid 0.4167926197926328 0.8770897102686283 0.3804379131803803 1.0 0.8025271330150076 14 P11717,Q9P0J0,O43464,P07948,O94788 5 +Regulation of macroautophagy 0.3064468643238842 0.8764287333809118 0.3807970035742221 1.0 0.8025271330150076 58 O15269,P21796,Q9NRR5,Q9Y2S7,Q93050,Q9H444,Q96EP0,P27544,O15118,Q8TBX8,Q9Y5K8,Q9NV70,P09601,Q96EB6,P31749,P46934,Q6UWE0 17 +Regulation of protein depolymerization 0.3365937289119377 0.8752746810586916 0.3814244669561633 1.0 0.8025271330150076 35 P25054,Q9NYL9,Q9Y3E1,P35611,P48681,P28289,Q9ULW0 7 +Intestinal absorption 0.4686134750185791 0.8747462995773513 0.3817119619625253 1.0 0.8025271330150076 9 Q16739,Q8WTV0 2 +Regulation of nervous system process 0.4131095698210755 0.874740745254508 0.3817149848033137 1.0 0.8025271330150076 15 Q9UQB8 1 +Purine deoxyribonucleotide metabolic process 0.5648124077464367 0.8708334857887334 0.3838450786658125 1.0 0.8055047149087807 5 P55263,P00813 2 +Wound healing 0.2894395339656617 0.8702698816020367 0.3841529342331107 1.0 0.8055047149087807 68 Q96AY3,Q16625,P46108,Q8WTV0,Q9HD42,P42785,P09601 7 +Histone h3 k36 trimethylation 0.7130935251798538 0.8687388519215434 0.3849899856373229 1.0 0.8055047149087807 2 Q96ST2 1 +Alditol phosphate metabolic process 0.563946388539843 0.8669792094091178 0.3859534012659393 1.0 0.805928818469724 5 Q9NPH0 1 +Cellular response to dsrna 0.4764210064766481 0.864358372975214 0.3873910527437585 1.0 0.8072444723449659 8 Q7Z434,O60828,P41440 3 +Negative regulation of small gtpase mediated signal transduction 0.4175487945333771 0.8632851302367135 0.3879807177367134 1.0 0.8073929592533458 13 P16949,O95630,Q9NUQ9,P37198 4 +Neutral lipid metabolic process 0.4032906383866915 0.8632422418738284 0.3880042929783749 1.0 0.8073929592533458 17 Q8NCC3,Q96EB6,Q8WTV0 3 +Calcium ion regulated exocytosis of neurotransmitter 0.7116546762589906 0.863029621869131 0.3881211806480515 1.0 0.8073929592533458 2 P16615 1 +Regulation of mitochondrial fission 0.4563825783303206 0.8626005820056061 0.3883571102660934 1.0 0.8073929592533458 10 Q9NQG6,O00429,Q9Y3D6,Q9NUQ9 4 +Positive regulation of rig i signaling pathway 0.6057297025532721 0.8605995716824194 0.3894586219260878 1.0 0.8084886136959649 4 Q9Y4E8 1 +Leukocyte proliferation 0.3250635284561405 0.8593236249866327 0.3901619935254174 1.0 0.8088322045458035 42 P30825,P49366,Q9HCL2,P04439,P14174,Q96EY1,P00813,Q96IZ0 8 +Regulation of neutrophil migration 0.4754390168153649 0.8591859957999017 0.390237908370179 1.0 0.8088322045458035 8 Q07021 1 +Regulation of protein containing complex disassembly 0.3187894562629089 0.8566358892969999 0.391646144722193 1.0 0.8104762712231564 45 Q9NRR5,P25054,Q9NYL9,O75844,Q9Y3E1,P35611,P48681,P28289,Q9ULW0 9 +Aging 0.2896580953995395 0.8558131748890285 0.3921011265786345 1.0 0.8111630527556115 72 P43246,O60313,Q14191,P16104,P00846,Q96EY1,Q96EB6,P02545,P30536,Q53EL6,O43464,O00330,P37198,P67809,O95983,Q86X55,Q9UGP8,Q96IZ0,Q96SB8,P42575,P14174,O75844,P05067 23 +Acylglycerol homeostasis 0.7238889217101111 0.8529086381370146 0.3937099710231553 1.0 0.8127052002103917 3 Q8WTV0 1 +Regulation of dendrite morphogenesis 0.4016880302884054 0.8523470570811151 0.394021495415199 1.0 0.8128168619029844 17 P46934 1 +Post anal tail morphogenesis 0.708776978417264 0.8516338774573851 0.3944173306610148 1.0 0.8128168619029844 2 Q15363 1 +Detection of external biotic stimulus 0.72337873434489 0.8510152044004236 0.3947609068399242 1.0 0.8130914708247142 3 Q8WTV0 1 +Regulation of gene silencing by rna 0.3856270872567798 0.8503216355498843 0.3951462910465899 1.0 0.8132911638923926 20 Q15717,P51114,Q06787,Q13546,Q14671,O60573,Q01085,O75844,O75376 9 +Intrinsic apoptotic signaling pathway 0.2908169466597305 0.8490845069830781 0.3958342707085012 1.0 0.8136875916757256 84 Q15118,P46379,Q8N163,Q9P0J0,O95831,Q96EB6,P31749,Q9UL15,P23246,Q9NR28,P45880,Q9Y3D6,P09601,Q15233,P09874,O75489,Q96RU2,P42575,P14174,Q9NYF8,P61978 21 +Leukocyte apoptotic process 0.3616898246897915 0.8466877619057749 0.3971691818522576 1.0 0.815275728435229 25 P24390,P00813,Q13546,Q9HCL2,Q99576,P14174,Q96EY1,Q96EB6,P31749 9 +Positive regulation of epithelial cell apoptotic process 0.6020071348334668 0.8451727216455628 0.3980144102847784 1.0 0.8154592504248772 4 Q53EL6 1 +Oxaloacetate transport 0.7067625899280552 0.8436753038116621 0.3988508714746885 1.0 0.8166651311829468 2 Q9UBX3 1 +Succinate transmembrane transport 0.7067625899280552 0.8436753038116621 0.3988508714746885 1.0 0.8166651311829468 2 Q9UBX3 1 +3 utr mediated mrna stabilization 0.4720247527297567 0.841227748153432 0.400220358347243 1.0 0.8184518749689584 8 Q15717,P98175,Q13151,Q13148 4 +Regulation of calcium mediated signaling 0.4621764235829058 0.8398860338011571 0.4009722890164375 1.0 0.8189432848475976 9 P00813,P0DP25 2 +Lymphocyte mediated immunity 0.3307670874809004 0.8395690794550371 0.4011500420626923 1.0 0.8189432848475976 37 P43246,O96028,P07437,Q9NUQ9,Q9UQ84,Q12888,P04439,Q96FV9,Q07021,P68371,P46108,Q5RKV6,Q5UIP0 13 +Ribonucleoside monophosphate biosynthetic process 0.3780440748953926 0.8394686167861418 0.4012063930016762 1.0 0.8189432848475976 21 P55263,P31939 2 +Regulation of synaptic vesicle exocytosis 0.4339666383176896 0.8364108505626991 0.40292381046854 1.0 0.8189856093838984 11 Q4J6C6,P05771 2 +Stem cell proliferation 0.4156887294853717 0.8361791971489941 0.4030540996315905 1.0 0.8189856093838984 12 P08183,Q9Y5A9 2 +Organic hydroxy compound metabolic process 0.2757645285516604 0.8358028318530507 0.4032658331215373 1.0 0.8189856093838984 120 P37268,Q9BZF3,O14734,Q8WTV0,P61457,Q96EB6,Q9BY49,P34913,Q10713,O94788,Q9BQE5,P00374,P35610,Q9UKG1,P30837,P21964,Q9H4L5,O75845,Q15392,P48735,Q9UHB6,Q6NUM9,Q16850,P48449,Q9NZC3,P05067 26 +Phospholipid homeostasis 0.7047482014388465 0.8357323100461532 0.403305514297203 1.0 0.8189856093838984 2 Q9HCL2 1 +Regulation of lymphocyte mediated immunity 0.3775014001132846 0.8353758864181325 0.403506102348709 1.0 0.8189856093838984 21 P43246,O96028,Q9NUQ9,Q12888,P04439,Q96FV9,P46108,Q5RKV6,Q5UIP0 9 +Centrosome separation 0.5566542585173819 0.8346113053418267 0.4039365947008118 1.0 0.8189856093838984 5 P37198 1 +Positive regulation by host of viral transcription 0.4984087492963547 0.8344701593059339 0.4040160960983097 1.0 0.8189856093838984 7 P50750,Q9H1E3 2 +Negative regulation of double strand break repair via homologous recombination 0.5561929758132435 0.8325692315896464 0.4050877177878154 1.0 0.8189856093838984 5 Q9NRR5,Q5UIP0 2 +Negative regulation of cellular response to growth factor stimulus 0.4150553571460501 0.8322984944324807 0.4052404802268592 1.0 0.8189856093838984 12 P18031,Q8N0X7,O14936,Q9Y2U8,O14964,P46934 6 +Negative regulation of phosphoprotein phosphatase activity 0.4606272334255063 0.8315186771622098 0.4056806816118423 1.0 0.8189856093838984 9 O75663,Q13464,Q15257 3 +Regulation of cell population proliferation 0.2858564418834858 0.831452732434435 0.4057179200436787 1.0 0.8189856093838984 245 O43663,Q8NEM2,Q9P032,Q9UPN4,Q8IXJ6,Q32P28,Q99816,Q7Z5K2,P49366,P12956,P04439,Q9NR77,Q96JM3,Q9UBL3,Q96EY1,Q96EB6,O95684,Q00577,P98175,Q92845,O94788,P43490,O95630,P25054,P02545,Q9NTI5,Q99439,Q8IWX8,P30536,Q9HCL2,Q9P266,Q53EL6,Q14534,P33981,P82970,Q52LJ0,O43815,P00813,P31749,Q96HY6,Q15058,P37198,P31751,P55209,Q04721,Q96ER3,P30825,Q15392,Q14978,P48681,Q99627,O43379,Q96DY7,P09601,Q01085,Q86X55,Q96IZ0,Q9BSK2,Q9UII2,Q96G23,Q15637,P52756,Q6ZWJ1,Q9NPI1,O14737,P43307,P14174,Q9H2J4,O75844,Q86Y37,P05067,Q96BK5 72 +Protein polyubiquitination 0.2986153812890086 0.8291797370781064 0.4070027091143622 1.0 0.8189856093838984 61 Q5VTR2,P55786,O75150,Q7Z7E8,P38398,Q8NEZ5,Q66K64,Q96EP0,P22681,O95155,Q9UIQ6,Q9UJX3,Q9UJX2,Q96PU5,P46934,Q6UWE0 16 +Early endosome to golgi transport 0.4599763643331439 0.828006022880155 0.4076670889827016 1.0 0.8189856093838984 9 Q9Y5X2,O15260,O60499,Q13596,O60749 5 +Cellular transition metal ion homeostasis 0.3630676758362709 0.8279943256447412 0.4076737134438173 1.0 0.8189856093838984 23 P09601,Q8NEW0,P05067,Q9Y5Y0 4 +Leydig cell differentiation 0.7024460431654653 0.8266741216852738 0.4084217928901508 1.0 0.8189856093838984 2 Q15637 1 +Cell adhesion mediated by integrin 0.459724887866927 0.826649284013128 0.4084358747213721 1.0 0.8189856093838984 9 P00813 1 +Glycoprotein biosynthetic process 0.3034912117327666 0.8243764278371349 0.4097257043115925 1.0 0.8189856093838984 57 Q8WVQ1,Q9NY61,P35610,Q8N6G5,O95394,Q96L58,O14734,O15118,Q08379,Q8NCH0,Q9NQX7,O60502,Q9H9S5,Q96IZ0 14 +Carbohydrate transport 0.3607004633994264 0.8227087897937055 0.4106736156327819 1.0 0.8189856093838984 24 P31751,Q6ZWJ1,Q16625,P31749,P05771 5 +Positive regulation of histone ubiquitination 0.5535497373858921 0.8208809798108191 0.4117140660421765 1.0 0.8205638176503027 5 Q5VTR2,O75150 2 +Primary alcohol metabolic process 0.3922520039231517 0.8202294300781536 0.4120853276470999 1.0 0.82080720189442 18 Q6NUM9,Q9BY49,P30837,O94788 4 +Negative regulation of transport 0.288453898862621 0.8192485603681742 0.4126446143691966 1.0 0.8216728208155445 90 P21796,O75608,O95429,Q8N183,Q9UKG1,Q6WKZ4,P00813,P31749,P46934,P31751,P53367,Q9Y3D6,P09601,Q13432,Q16850,O00233,P0DP25,Q96PU5,P05067,P05771 20 +Regulation of leukocyte mediated immunity 0.3422092846363957 0.8163358048045034 0.4143081014755707 1.0 0.8222177514099135 31 P43246,O96028,Q9NUQ9,Q9UJ41,Q12888,Q7Z434,P04439,Q96FV9,P46108,P09601,Q5RKV6,P07948,Q5UIP0 13 +Chromatin disassembly 0.4039812674199872 0.8154579176894656 0.4148102434048204 1.0 0.8225051741782612 15 Q01105 1 +Negative regulation of rig i signaling pathway 0.5943574075723977 0.81360412950372 0.4158717714460413 1.0 0.8231322303291233 4 Q07021 1 +Regulation of map kinase activity 0.374505851198059 0.8128175124177885 0.4163226934119621 1.0 0.8234580586217599 21 P18031,Q99816,Q96JB5,Q53EL6,P04035,P14174,O14964,P37198,P07948 9 +Positive regulation of dna templated transcription initiation 0.4093117686214866 0.811867674610951 0.4168675647175952 1.0 0.8236103100222595 13 P53999,Q9NPJ6 2 +Negative regulation of cysteine type endopeptidase activity 0.3591551757571405 0.8101707100346617 0.4178420690179629 1.0 0.8240530957076797 24 Q15418,P31749,P51812 3 +Corticosteroid receptor signaling pathway 0.4932348273100629 0.8090073527787831 0.4185109169434646 1.0 0.8248783822137268 7 P46934 1 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4931067399864631 0.8083781951452081 0.4188729003872713 1.0 0.8253449583288669 7 Q8N163,P14174 2 +Nucleoside monophosphate metabolic process 0.3273381644905825 0.805238906882458 0.420681828725022 1.0 0.8265048671737606 37 P55263,P31939,P49902 3 +Regeneration 0.3302927511883344 0.8047735324686808 0.4209503777296388 1.0 0.8265048671737606 34 P31939,Q96G23,P30536,P00374 4 +Regulation of cell adhesion mediated by integrin 0.4650417047280977 0.8046328088944646 0.4210316034987338 1.0 0.8265048671737606 8 P00813 1 +Regulation of ras protein signal transduction 0.3338639342429145 0.8029907569873678 0.421980076968284 1.0 0.8265048671737606 33 P16949,O95630,P41440,P22681,P46108,Q13501,Q8N6T3,P37198 8 +Chemokine c c motif ligand 5 production 0.6961151079136667 0.8018756169080904 0.4226249119403449 1.0 0.8265584876149992 2 Q7Z434 1 +Positive regulation of chemokine c c motif ligand 5 production 0.6961151079136667 0.8018756169080904 0.4226249119403449 1.0 0.8265584876149992 2 Q7Z434 1 +Branching involved in labyrinthine layer morphogenesis 0.6958273381294939 0.8007524216095134 0.423274988017186 1.0 0.8273387410398215 2 Q15363 1 +Process utilizing autophagic mechanism 0.2679377292138349 0.7997341504610348 0.4238648422770144 1.0 0.828245980356835 175 P21796,Q9Y2S7,Q8IXJ6,Q99816,Q13464,Q93050,P16615,O00189,O00429,Q8TBX8,Q9NV70,Q13501,Q96EB6,Q9Y3E7,Q9H9H4,O15269,Q8NCE2,Q9Y6I9,O00165,P30536,Q9H444,P27544,O15118,O43464,O15027,Q9P253,Q9HD42,O14964,P36543,P31749,Q86UE4,Q96HY6,P46934,Q6UWE0,Q9P275,Q9NRR5,Q9Y679,Q9Y4P1,Q9Y3D6,Q7KZI7,Q9NZZ3,P09601,O95721,Q9UPT5,O14681,Q9UII2,Q96HS1,Q9UNZ2,Q969Q5,Q96EP0,Q9UNE7,Q9Y263,Q5T8D3,Q9UI12,Q86UE8,Q9Y5K8,Q08379,O75844,Q7Z3C6 59 +Regulation of oxidative stress induced cell death 0.3783470194973803 0.7970323410501537 0.4254322487639026 1.0 0.8295865898506523 20 P09874,P23246,Q13546,Q96EB6,P31749,Q96IZ0,Q9UL15 7 +Response to epidermal growth factor 0.3975322356764498 0.7959628445267909 0.4260536318018517 1.0 0.830306826365691 16 O75312,Q9UQB8,O95429,Q96A49,P31749 5 +Glial cell differentiation 0.3132303598076698 0.7952449455337837 0.426471031696177 1.0 0.8308745203566265 45 P08670,P31749,P05067,Q8IXJ6 4 +Regulation of cellular response to insulin stimulus 0.3930484111912187 0.793850271886192 0.4272826023011875 1.0 0.8314664486051093 17 P18031,Q9H1E3,Q96EB6,Q8TBX8,Q9HCD5,P05771 6 +Regulation of response to extracellular stimulus 0.5470425877259277 0.7922077819708894 0.4282395317785377 1.0 0.8319710494607148 5 P80303,Q13573,Q9UMX5 3 +Negative regulation of regulated secretory pathway 0.5469033129804654 0.7915957289970851 0.4285964380789988 1.0 0.8319710494607148 5 P09601,Q9UJ41 2 +Sulfate transport 0.7069660333908963 0.7905282897998934 0.4292193074774946 1.0 0.8319710494607148 3 Q9UBX3,Q9H0H5 2 +Positive regulation of response to endoplasmic reticulum stress 0.4529447385104418 0.7901689539294109 0.4294291045404872 1.0 0.8319710494607148 9 O43765,Q96EB6,P46379 3 +Skeletal muscle cell differentiation 0.4526829639205519 0.7887645253441112 0.4302496469101948 1.0 0.8319710494607148 9 Q9BYT8,P50402,Q92841 3 +Protein processing involved in protein targeting to mitochondrion 0.7064483281037088 0.7886346312103368 0.4303255839746394 1.0 0.8319710494607148 3 Q10713 1 +Response to peptide 0.281218319803163 0.7875068256368276 0.4309852343392508 1.0 0.8319710494607148 107 O75150,Q99523,Q8TBX8,Q96EB6,P25054,Q9UKG1,Q96A49,P31749,P31751,Q9UQB8,P08670,Q15043,Q9BSK2,P09874,Q6ZWJ1,P09960,P46108,Q9HCD5,P33527,P05067,P05771 21 +Keratinocyte proliferation 0.4886776047524032 0.7866607511265229 0.4314804857927301 1.0 0.8319710494607148 7 Q6ZWJ1 1 +Regulation of keratinocyte proliferation 0.4886776047524032 0.7866607511265229 0.4314804857927301 1.0 0.8319710494607148 7 Q6ZWJ1 1 +Vacuolar acidification 0.4520329559458779 0.7852785820758516 0.4322902505469317 1.0 0.8319710494607148 9 Q93050,O75787,P50897,O75503 4 +Growth hormone receptor signaling pathway via jak stat 0.7052571050766461 0.7842809173871759 0.4328752940684346 1.0 0.8319710494607148 3 P18031 1 +Protein acylation 0.2832605772668865 0.7839360198155104 0.4330776530141382 1.0 0.8319710494607148 68 Q00403,P46379,O75844,Q03164,Q9NPI1,P38398,O95983,Q5T5X7,O60318,Q86U70,Q01105,Q9NYB0,Q96ST2,Q86UY6,Q96EB6,O95619,Q92830,Q5VZE5 18 +Positive regulation of glycoprotein metabolic process 0.4608022698211618 0.7825134534715316 0.4339128820023459 1.0 0.8319710494607148 8 Q96IZ0,Q08379 2 +Single strand break repair 0.5445253248976334 0.7811566562762798 0.4347103628260673 1.0 0.8319710494607148 5 P09874 1 +Heart morphogenesis 0.3383492643373683 0.7811316009244912 0.4347250974931382 1.0 0.8319710494607148 31 Q15363,O96028,Q53EL6,O75844,O94788 5 +Positive regulation of dna recombination 0.3494071009097254 0.780893299344707 0.4348652534017996 1.0 0.8319710494607148 27 P43246,O96028,P09874,Q96B01,P35637,Q12888,Q7Z4V5,Q9UBU8,O95619,Q5RKV6,Q5UIP0 11 +Lytic vacuole organization 0.3514884700917385 0.7794768564923144 0.4356988655224012 1.0 0.8324616536834476 26 Q96ED9,P11117,Q14108,O75503,Q8N511,O75787,Q9P253,P50897,Q12768 9 +Protein demethylation 0.450759499869583 0.7784548773671349 0.4363008978019698 1.0 0.8325475284150532 9 P29375,Q9UPP1,Q9Y570,Q7LBC6,Q8NB78 5 +Regulation of histone h3 k14 acetylation 0.7033462747423749 0.7773075804709301 0.4369773237322727 1.0 0.8331144635624841 3 Q96EB6 1 +Cellular response to ionizing radiation 0.3530282804510922 0.775367139198034 0.43812274689636 1.0 0.8334533633808123 25 P16104,O75844,Q96B01,Q9H1E3,P12956,Q96EB6,Q14191 7 +Muscle cell development 0.3344304487703748 0.7753147617752827 0.4381536886798662 1.0 0.8334533633808123 32 Q9NYL9,Q9H7B4,P28289,Q9UGN5,O75844 5 +Regulation of neurogenesis 0.2958106455363472 0.7752440685214476 0.438195452470455 1.0 0.8334533633808123 60 P55209,Q9UQB8,Q8IXJ6,P30536,Q96G23 5 +Regulation of pattern recognition receptor signaling pathway 0.356343841462849 0.7743468203114077 0.4387257229306756 1.0 0.8334533633808123 23 Q96RT1,P41440,Q9UKG1,Q01804,Q14671,Q9NQC3,Q07021,Q86UT6,Q9Y4E8,P07948 10 +Notch signaling pathway 0.3751153672288769 0.7734904423146708 0.439232182995287 1.0 0.8334533633808123 20 Q9Y5A9,P31749,P05067 3 +Antigen receptor mediated signaling pathway 0.3484390926936336 0.7726920386814962 0.4397046594333504 1.0 0.8334533633808123 27 P00813,Q96IZ0,P05771 3 +Plasma membrane phospholipid scrambling 0.6883453237410047 0.7716778133839947 0.4403052744730806 1.0 0.8334533633808123 2 Q7Z3C6 1 +Negative regulation of cell volume 0.6883453237410047 0.7716778133839947 0.4403052744730806 1.0 0.8334533633808123 2 P51790 1 +Protein localization to microtubule organizing center 0.3971680344709198 0.7715077854988223 0.4404060094801774 1.0 0.8334533633808123 15 P25054,Q9UPN4,Q9UNZ2,Q14789,Q13561,Q15154,P37198 7 +Response to catecholamine 0.380063266730287 0.7702167202740865 0.4411713472189014 1.0 0.8343996610209372 19 Q8IXJ6 1 +Cardiac muscle tissue development 0.3337335409861974 0.7688541243403297 0.4419799139130802 1.0 0.8349213454051851 32 O75844,Q9UGN5,O94788 3 +Cellular response to retinoic acid 0.4044656891960652 0.7677298983037891 0.4426476696402752 1.0 0.8349298201140805 12 Q9P0J0,O43464,P07948,O94788 4 +Mesenchymal cell differentiation 0.3300078230289613 0.7664755448777185 0.4433933975848207 1.0 0.835545299818181 33 Q99729,Q53EL6,Q9UBV8,Q9UK61,O94788 5 +Regulation of response to external stimulus 0.2580774280088992 0.76494348032669 0.4443052011361255 1.0 0.835545299818181 149 Q8IXJ6,P28070,Q9Y5A9,P12956,P04439,Q86UT6,Q9UMX5,Q9UKG1,Q53EL6,Q9BXW9,Q07021,Q9Y3Z3,Q96PK6,P00813,Q6UWE0,P23246,P43243,Q00013,Q14166,Q13546,Q8WXF1,P80303,P46108,P14174,Q96G23,O75844,P33527,P05067,Q9NZ08 29 +Immune response regulating signaling pathway 0.2818807360987982 0.7647322960732351 0.4444309706705835 1.0 0.835545299818181 68 P51812,P41440,P46379,Q07666,Q01804,P04439,Q07021,Q86UT6,P00813,Q96IZ0,P05771 11 +Ncrna export from nucleus 0.457371634269184 0.7646735335963962 0.4444659699290825 1.0 0.835545299818181 8 Q9H814 1 +Cardiac cell development 0.395968667219373 0.7638014242906671 0.4449855879355746 1.0 0.8358734769810355 15 O75844,Q53EL6,Q9UGN5 3 +Positive regulation of protein dephosphorylation 0.3989148222389418 0.7636321018551371 0.4450865133526736 1.0 0.8358734769810355 14 Q15257,Q86XL3 2 +Negative regulation of bmp signaling pathway 0.581567603381657 0.7612713840981388 0.4464949888713794 1.0 0.837099536481434 4 Q9Y2U8 1 +Regulation of ire1 mediated unfolded protein response 0.5058786134726398 0.7607448278713104 0.4468094939088083 1.0 0.8373230248478777 6 Q92905,Q96HY6 2 +Negative regulation of interleukin 6 production 0.5810967712118255 0.7593565874245867 0.4476392754252352 1.0 0.8376085761835149 4 Q86UT6 1 +Regulation of phosphatase activity 0.3731143795593638 0.7589530154227121 0.4478806634145931 1.0 0.8376085761835149 20 O95429,P0DP25,Q96JB5,Q15257,O75663 5 +Gland development 0.2841103047001212 0.7585922760014339 0.4480964946002199 1.0 0.8376085761835149 78 P31751,O75844,Q99808,Q15418,P30536,P09601,P00813,P31749,O94788 9 +Semi lunar valve development 0.5053446282042743 0.7582594064468643 0.4482957035857651 1.0 0.8376085761835149 6 Q04721 1 +Regulation of innate immune response 0.3018992479816473 0.7573175998038559 0.4488596092159853 1.0 0.8376085761835149 53 Q9NW08,Q9Y5A9,P12956,P04439,Q86UT6,O60828,P07948,Q7Z739,Q9UKG1,Q9Y3Z3,Q96PK6,P23246,Q7Z434,P43243,Q9Y4E8,Q15233,Q14166,P18031,P46108,Q8WXF1,Q9NZ08 21 +Meiotic cell cycle process 0.3072377687955698 0.7526367091376952 0.4516682521020767 1.0 0.8411650969758574 46 P46379,Q08J23,Q8IXJ6,Q9Y5A9,Q9BXW9,Q92791,Q08379,Q9BTX1 8 +Dicarboxylic acid transport 0.3940892357788768 0.7517452050937078 0.4522042997156648 1.0 0.841925439623203 15 Q9BQT8,P41440 2 +Protein geranylgeranylation 0.5788596894376046 0.7502709085004885 0.4530915599499141 1.0 0.8421167716759562 4 P49354,Q92696 2 +Mast cell activation involved in immune response 0.481008108248434 0.7492443780339606 0.4537099258059405 1.0 0.8425858796886533 7 P09601,P22681,Q9UJ41 3 +Regulation of systemic arterial blood pressure 0.4535325937682761 0.7447777773121798 0.4564060713027968 1.0 0.8441197711718205 8 P42892 1 +Synaptic vesicle exocytosis 0.3761008691921457 0.7422467862314301 0.4579378264438982 1.0 0.8441676028804401 19 Q4J6C6,P0DP25,Q5SQN1,O95721,P05771 5 +Respiratory system development 0.3469173210287573 0.7414643815794746 0.4584119205540702 1.0 0.8441676028804401 26 P00813,O94788 2 +Protection from non homologous end joining at telomere 0.535329522559061 0.7409988340032073 0.4586941472943016 1.0 0.8441676028804401 5 Q9UBB9 1 +Pyridine containing compound metabolic process 0.4523408826423965 0.7386171379146746 0.4601395146121043 1.0 0.845013131907707 8 Q9BQG2 1 +Regulation of insulin secretion 0.3485339055570798 0.7386051805287573 0.4601467775511993 1.0 0.845013131907707 25 Q8N183,O00233,P00367,P53985 4 +Regulation of histone h3 k9 methylation 0.4166244144457567 0.7360476977038586 0.4617016707911832 1.0 0.8463033722390633 11 P02545,Q9NWS0,P38398,Q96EB6,Q8WTS6,Q5UIP0 6 +Regulation of cartilage development 0.4781531970865572 0.7353835059115617 0.462105964197304 1.0 0.8463033722390633 7 Q92830 1 +Regulation of cysteine type endopeptidase activity 0.2951074861911943 0.7348664755121921 0.462420817221028 1.0 0.8463033722390633 58 P51812,Q9NR28,Q9BXK5,Q9HB09,Q15418,Q15392,O14737,Q9P0J0,P42575,Q9Y3D6,O95831,Q96EB6,P31749 13 +Response to salt 0.5750480666898727 0.7348379729200005 0.4624381777605786 1.0 0.8463033722390633 4 Q9UER7,P09651 2 +Negative regulation of phosphatase activity 0.4163904046213662 0.7347050990877657 0.4625191141953053 1.0 0.8463033722390633 11 O75663,Q15257 2 +Positive regulation of peptidase activity 0.303254539785285 0.7329250870447145 0.4636041211762922 1.0 0.8478178058369663 47 Q9NR28,Q9BXK5,Q9UL46,O14737,P05067,Q9P0J0,Q9Y3D6,P61289,O95831,Q96EB6,Q96HY6 11 +Positive regulation of neural precursor cell proliferation 0.4771515386330309 0.730529566476675 0.4650665471160042 1.0 0.8482524878474778 7 O43379,P55209,P48681 3 +Cellular response to light stimulus 0.3295744088293433 0.7304024424058111 0.4651442258790952 1.0 0.8482524878474778 32 P09874,Q96RU2,P46934 3 +Negative regulation of intrinsic apoptotic signaling pathway 0.3260630301485083 0.729279339662627 0.4658308075602573 1.0 0.8482524878474778 33 O60313,O75489,P18031,Q8N163,P45880,Q9P0J0,O43464,P14174,Q96EB6,P31749,Q15233,Q9UL15 12 +Dna modification 0.322311273259555 0.727790923373744 0.4667415815948343 1.0 0.8482524878474778 34 P09874,Q5T5X7,Q9UGN5,O75844,Q5RKV6 5 +Positive regulation of pattern recognition receptor signaling pathway 0.4319063387486035 0.7273077266506301 0.4670374658942553 1.0 0.8482524878474778 10 Q9NQC3,Q14671,Q9Y4E8,P41440 4 +Protein targeting to lysosome 0.3953068305664708 0.7253312733097237 0.4682488245176719 1.0 0.8492050032023727 13 Q9Y2T2,Q99523,Q14108,O00189,O14964,P46934 6 +Regulation of mitotic cytokinesis 0.6889346929009166 0.7251532521642339 0.468358018157144 1.0 0.8492050032023727 3 P37198 1 +Apoptotic signaling pathway 0.2579686126306191 0.7240402980181079 0.469040995394508 1.0 0.8497418528057227 155 Q15118,P46379,Q99523,Q8N163,Q9P0J0,Q9NQX7,O95831,Q96EB6,P02545,Q9HB09,O95155,P61289,Q9UGN5,P31749,Q9UL15,P23246,Q9NY61,Q9NR28,Q3ZCQ8,P45880,Q9Y3D6,P09601,Q9UER7,Q15233,Q96IZ0,Q9UII2,P09874,O75489,Q13546,Q96RU2,O14737,P14174,Q8IWB1,Q9NYF8,P61978 35 +Dna unwinding involved in dna replication 0.3732631169972332 0.7222943491474774 0.4701135263894216 1.0 0.8502776442022987 19 P33991,Q14191,Q04837,Q9BRT9,Q14566,O94761,Q9Y248,Q00577 8 +Cardiac epithelial to mesenchymal transition 0.6879093335560361 0.7214738429365944 0.4706180283823027 1.0 0.8502776442022987 3 Q53EL6 1 +Cardiac muscle cell differentiation 0.3731141889779019 0.7212491494198899 0.4707562370693559 1.0 0.8502776442022987 19 O75844,Q9UGN5 2 +Positive regulation of fat cell differentiation 0.4972974240813678 0.7209535799995912 0.4709380755439238 1.0 0.8503729733513056 6 Q96A49,P31749 2 +Response to lipid 0.2584419807560155 0.720679529973768 0.4711067096067616 1.0 0.850444413588754 157 Q13126,Q9H7B4,O15228,P04150,Q9P0J0,Q8WTV0,Q96JM3,Q96JN0,O95831,Q96EB6,O94788,Q13151,P30536,Q53EL6,Q92841,P22681,O15118,Q9P253,P31749,P46934,P51812,P08670,O15173,O95983,O43823,Q8N7H5,P09874,P0DP25,P14174,P49321 30 +Response to estradiol 0.3775328216678674 0.7188250716355273 0.4722487078164203 1.0 0.8513397361976454 18 O95831,Q96JN0,O94788 3 +Monocarboxylic acid transport 0.4395193325887162 0.7185854763110345 0.4723963647199336 1.0 0.8513729888237536 9 P53985 1 +Regulation of translational initiation by eif2 alpha phosphorylation 0.5705557644687161 0.7167294442693798 0.4735410541506071 1.0 0.8518562621106698 4 Q15363,Q13217 2 +Nucleoside monophosphate biosynthetic process 0.3458406085094694 0.7166698079493458 0.4735778595388926 1.0 0.8518562621106698 25 P55263,P31939 2 +Neuron projection guidance 0.3456588562038675 0.7151922810908494 0.4744902380154543 1.0 0.8528140148073728 25 P42892,P05067 2 +Response to extracellular stimulus 0.281242235183631 0.714581918048629 0.474867421131514 1.0 0.8532591867563529 92 Q8IXJ6,Q9UMX5,P35610,O15228,P30536,P31749,Q8NEZ5,P53985,O95983,P22681,P80303,Q92830,Q01130,O95831,Q96EB6,Q9H773,P09601,O94788 18 +Regulation of entry of bacterium into host cell 0.6856649395509407 0.7134353882399711 0.4755763814408578 1.0 0.8540672601018838 3 Q9UPT5,Q9BTY2 2 +Regulation of nitric oxide metabolic process 0.3932137160129326 0.7125132694281111 0.4761469974594288 1.0 0.8543934003976514 13 P30536,P31749 2 +Negative regulation of hormone secretion 0.4382262776169779 0.7117434513344916 0.4766236555674579 1.0 0.8546547842377039 9 Q8N183,O00233 2 +Cristae formation 0.4380174106487288 0.7106392065681075 0.4773078409992568 1.0 0.8551839307373568 9 Q16891,Q5XKP0,Q9NX63,Q9Y512 4 +Regulation of granulocyte chemotaxis 0.4286269631254483 0.7094193617900756 0.478064276086549 1.0 0.8559688899821389 10 Q07021 1 +Regulation of anion transport 0.4278394586342617 0.7051337283188894 0.4807270185288044 1.0 0.8582437897128465 10 P08183,P14174 2 +Peptidyl lysine dimethylation 0.4456613298508674 0.7042314745548509 0.4812886330230639 1.0 0.8582437897128465 8 O15047,Q8WTS6 2 +Negative regulation of calcium ion transmembrane transport 0.4364845687083681 0.7025435290176726 0.4823402655344275 1.0 0.8598863662354824 9 P21796 1 +Cellular response to nitrogen compound 0.2548410250204819 0.7013430334995796 0.4830889638460303 1.0 0.8605323456636882 149 Q8IXJ6,Q96JM3,Q8TBX8,O95831,Q99729,P41440,Q96A49,P31749,P31751,Q9UQB8,P08670,Q15043,Q9BSK2,P09874,Q6ZWJ1,P46108,P33527,P05067,P05771 19 +Stress granule assembly 0.3792145523433401 0.7012294402116139 0.4831598398462087 1.0 0.8605323456636882 17 Q14011,Q14157 2 +Cellular response to growth hormone stimulus 0.5660719828561759 0.6987466347560645 0.4847103841653772 1.0 0.8622229244212725 4 P18031 1 +Protein kinase b signaling 0.3414936109361854 0.6966354819929849 0.4860309446778019 1.0 0.8622665305552065 26 Q8IXJ6,O00165,Q07021,Q96EB6,P31749 5 +Positive regulation of cellular amide metabolic process 0.2786168226402415 0.6962612391260038 0.4862652425932414 1.0 0.8624499820852942 73 O60506,P51114,P98179,Q14011,P08670,Q9Y5A9,Q9NTG7,Q9Y2R0,Q07666 9 +Endosome organization 0.3182295757105398 0.6960343356966702 0.4864073271400977 1.0 0.8624698273751625 35 Q96ED9,Q9BTU6,Q14108,Q9H444,Q13501,Q9HD42,Q12768,Q9H9H4 8 +Muscle structure development 0.2778224894371198 0.6943568528724844 0.4874584452671517 1.0 0.8632513929778154 101 Q8IXJ6,Q9H7B4,Q99523,Q9BYT8,Q9P2K5,Q96EB6,P02545,P41440,Q53EL6,Q92841,Q96PU8,P28289,Q9UGN5,P31749,P67809,Q9NYL9,Q92830,P51114,Q8NEZ5,O75844 20 +Positive regulation of endothelial cell proliferation 0.3877075708682169 0.6935417452610498 0.487969637628959 1.0 0.8632513929778154 14 P09601,Q96EB6,Q9P266,P31749 4 +Positive regulation of fibroblast proliferation 0.4693879799135371 0.6930811971307719 0.4882585968609501 1.0 0.8634288498971552 7 P14174 1 +Peptidyl lysine acetylation 0.2955342675552098 0.6915212910438314 0.4892380055255074 1.0 0.8638674567800444 54 Q00403,P46379,O75844,Q03164,Q9NPI1,P38398,O95983,Q5T5X7,O60318,Q86U70,Q86UY6,Q96EB6,O95619,Q92830,Q01105 15 +Regulation of system process 0.276446336366253 0.6894432328712456 0.4905443850155657 1.0 0.8646861832176466 68 P09874,Q9UQB8,O75844,P42892,Q9UGN5,P00813 6 +Regulation of multicellular organism growth 0.3769367782173213 0.6861296567216864 0.4926313509878359 1.0 0.8666040640151311 17 O75844 1 +Mitotic dna replication checkpoint signaling 0.5627519680179877 0.6854930160637172 0.4930328662012169 1.0 0.8666040640151311 4 Q9Y619 1 +Nerve growth factor signaling pathway 0.6777437737120358 0.6852396813608067 0.4931926875595074 1.0 0.8666040640151311 3 Q99523 1 +Lipid homeostasis 0.3379761048983538 0.6846439778526882 0.4935686085757804 1.0 0.8666040640151311 27 Q5BJF2,O15254,P35610,Q9HCL2,Q15067,O15118,Q8WTV0,Q9UHB6,Q96EB6,P34913 10 +Regulation of double strand break repair via nonhomologous end joining 0.4415662200222789 0.6832805644630859 0.4944295729200527 1.0 0.8666040640151311 8 O96028 1 +Proton transporting v type atpase complex assembly 0.6650359712230187 0.6828598091913147 0.4946954323115982 1.0 0.8666040640151311 2 Q8N511 1 +Vacuolar proton transporting v type atpase complex assembly 0.6650359712230187 0.6828598091913147 0.4946954323115982 1.0 0.8666040640151311 2 Q8N511 1 +Response to reactive oxygen species 0.312689142980201 0.6827907302666025 0.4947390879811322 1.0 0.8666040640151311 39 P00374,Q99720,O95831,P31749,Q96IZ0,P09601 6 +Antigen processing and presentation of peptide antigen 0.3901473398496688 0.6815789266374341 0.4955052438827305 1.0 0.8669385671254349 12 Q9UIQ6,Q9NZ08,P10321 3 +Protein localization to condensed chromosome 0.3899873305353041 0.6806250894588018 0.4961087472613745 1.0 0.8669385671254349 12 Q8NG31,Q13123,Q96EA4,Q96JM3,Q96DY7 5 +Lipid droplet formation 0.675665498680438 0.6778887585021802 0.4978422281321544 1.0 0.8684888644857732 3 Q14534 1 +B cell differentiation 0.378987313355995 0.6750354966210287 0.4996532129903965 1.0 0.8693916103826776 16 P00813,P55327 2 +Regulation of histone deacetylation 0.3870558605133114 0.6750064775101291 0.4996716495677376 1.0 0.8693916103826776 13 Q9ULX6,O43823 2 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4870380671640903 0.673842292271439 0.5004115837552876 1.0 0.8698393567801125 6 P14174,P61978 2 +Cellular response to abiotic stimulus 0.277486447135491 0.6730372480421056 0.500923594335736 1.0 0.8698393567801125 75 P09874,P16104,P30536,Q96RU2,P12956,O75844,P46934 7 +Cellular response to peptide hormone stimulus 0.2766021448670358 0.6722216654109179 0.501442590338782 1.0 0.8698393567801125 72 P31751,P09874,Q9UQB8,P25054,Q6ZWJ1,Q15043,Q9UKG1,Q9HCD5,P46108,Q8TBX8,Q96A49,Q96EB6,P31749,Q9BSK2,P05771 15 +Regulation of voltage gated calcium channel activity 0.5192715292583703 0.671790593746545 0.5017170177744159 1.0 0.8698393567801125 5 P0DP25 1 +Myeloid leukocyte cytokine production 0.430403272923276 0.6705742262864555 0.5024918061313037 1.0 0.870096864136502 9 P09601,P14174 2 +Calcium mediated signaling 0.3606540569063048 0.669220096023618 0.5033550887804574 1.0 0.8702444077858068 20 P00813,Q9Y3D6,O75844,P0DP25 4 +Chemical homeostasis 0.2673973143599548 0.6691109641261255 0.5034246964400697 1.0 0.8702444077858068 197 P30519,P06576,Q93050,P49366,Q8WTV0,Q96EB6,P34913,Q5BJF2,P16949,Q8IWX8,Q99808,P35610,Q8N183,P30536,Q9HCL2,Q9H1E3,Q15067,P62995,Q9Y5Y0,P31749,Q15043,Q16739,O75503,Q9UHB6,Q9Y3D6,Q9HD20,P09601,P98194,Q8IYU8,P42785,P09874,O15254,Q6ZWJ1,P0DP25,P53985,Q8NEW0,Q9HCD5,Q96PU5,P05067,P50897,P05771 41 +Somatic diversification of immune receptors via somatic mutation 0.4643691434165711 0.6690480244507783 0.5034648435997795 1.0 0.8702444077858068 7 O60318,Q9Y3Z3,Q9UQ84 3 +Phenol containing compound catabolic process 0.6610071942446014 0.6678100901927029 0.5042548248870635 1.0 0.8707716043479851 2 P21964 1 +Response to nutrient 0.3257980622428694 0.6677317841588891 0.5043048174521036 1.0 0.8707716043479851 31 P09601,Q01130,P30536,O94788 4 +Aggrephagy 0.558010182175983 0.6666592678444682 0.5049898021834931 1.0 0.871188656242193 4 Q5T8D3 1 +Positive regulation of mitochondrial fission 0.4382353547346831 0.6663186535752188 0.5052074450601638 1.0 0.871188656242193 8 Q9NQG6,O00429,Q9Y3D6 3 +Positive regulation of dephosphorylation 0.3806027038430886 0.6660363532215811 0.5053878644348695 1.0 0.8712482876388371 15 Q15257,Q86XL3 2 +Formation of translation preinitiation complex 0.4286201242341468 0.661247839030077 0.5084533864521981 1.0 0.8756940555767555 9 P55010 1 +Cholesterol storage 0.67037439441223 0.6592659051533537 0.5097250323703315 1.0 0.8766844788013872 3 Q8WTV0 1 +Chondroitin sulfate proteoglycan biosynthetic process 0.5558155226136142 0.6579819591393127 0.5105497238106929 1.0 0.8774260986103147 4 Q8N6G5 1 +Chondroitin sulfate biosynthetic process 0.5558155226136142 0.6579819591393127 0.5105497238106929 1.0 0.8774260986103147 4 Q8N6G5 1 +Cerebellar purkinje cell layer morphogenesis 0.6699801111927715 0.6578835748272083 0.5106129458046147 1.0 0.8774260986103147 3 Q86U70 1 +Positive regulation of anion transport 0.4827377439513038 0.6542629132878812 0.5129424350609888 1.0 0.8796922708529036 6 P08183 1 +Negative regulation of telomere maintenance 0.3757091074330473 0.6539635755302067 0.5131352728062397 1.0 0.8797939923289914 16 P09874,Q9H0A0,P09651,Q9NYB0,Q9NVN8,Q96BK5 6 +Mitochondrial proton transporting atp synthase complex assembly 0.6687845413119671 0.6536966690742181 0.5133072496736815 1.0 0.8798599032517918 3 Q5TC12 1 +Positive regulation of inflammatory response 0.3811747895531279 0.653161993014859 0.5136518498246456 1.0 0.8798696282236177 14 P05067,P33527,Q53EL6 3 +Regulation of membrane depolarization 0.4177702778122603 0.6507108080627169 0.5152331849872345 1.0 0.8799948355951026 10 P30536 1 +Positive regulation of muscle hypertrophy 0.4265349832222381 0.6503708833272207 0.5154526803652764 1.0 0.8799948355951026 9 Q9UGN5 1 +Memory 0.4173869969055206 0.6486538499057035 0.5165621404268168 1.0 0.8806281871338412 10 Q92830 1 +Fatty acid beta oxidation using acyl coa oxidase 0.481122160117071 0.6469348265830601 0.5176741247717587 1.0 0.8811349113431289 6 Q15067,O14734 2 +Negative regulation of lymphocyte mediated immunity 0.5528295169850631 0.6462175445252792 0.5181384788692314 1.0 0.8811349113431289 4 P04439,P46108 2 +Liposaccharide metabolic process 0.3667671126227766 0.6458144526437845 0.5183995270100619 1.0 0.8811349113431289 18 P06865,Q99805,Q16739,Q8NBX0 4 +Negative regulation of muscle cell apoptotic process 0.5126391304958021 0.6435978526738099 0.5198362430665191 1.0 0.8821048319300717 5 Q8NDZ4,P09601 2 +Positive regulation of oxidative stress induced cell death 0.5124580296582353 0.6428315757381914 0.5203333920207416 1.0 0.8821048319300717 5 Q96IZ0,Q13546 2 +Dna methylation 0.3457824036056385 0.6424224784844902 0.5205989084733518 1.0 0.8821048319300717 22 P09874,Q03164,Q5T5X7,O95983,O75844 5 +Regulation of neural precursor cell proliferation 0.3737328971074819 0.6413127911780819 0.5213194803252701 1.0 0.8822869980252707 16 P55209,Q8IXJ6 2 +Positive regulation of mitochondrial depolarization 0.6652022054800999 0.6411940691256719 0.5213966024910581 1.0 0.8822869980252707 3 P30536 1 +Positive regulation of synapse assembly 0.6538129496402848 0.6411806095124912 0.521405346262666 1.0 0.8822869980252707 2 Q9NUL3 1 +Glomerular visceral epithelial cell migration 0.6532374100719396 0.6390642921708876 0.5227811080932951 1.0 0.8830634985864789 2 Q13464 1 +Regulation of dna templated transcription initiation 0.3733780745562386 0.6390456858707436 0.5227932118182004 1.0 0.8830634985864789 16 P53999,Q9NPJ6 2 +Regulation of cell division 0.310416310998572 0.6377695364985565 0.5236237126976904 1.0 0.8830634985864789 37 O43663,P67809,Q9Y2S7,Q8IXJ6,O75400,P0DP25,O95235,Q96C92,P41208,Q86Y91,Q92830,P37198 12 +Response to vitamin 0.3784747092881893 0.6365899189035833 0.5243919934299097 1.0 0.8830634985864789 14 P30536,O94788 2 +Regulation of mitochondrial membrane permeability involved in apoptotic process 0.3825221471967462 0.6363764397457413 0.5245310933374179 1.0 0.8830634985864789 12 P45880 1 +Regulation of stem cell population maintenance 0.4574747507777733 0.636282527465451 0.5245922911960639 1.0 0.8830634985864789 7 Q5T200,Q92830 2 +Lymphocyte activation involved in immune response 0.3299961050831174 0.6362721504423496 0.5245990535988332 1.0 0.8830634985864789 28 O96028,P00813,Q9UQ84 3 +Regulation of type i interferon mediated signaling pathway 0.3783507537430732 0.6358308759144495 0.5248866606298708 1.0 0.8830634985864789 14 Q14166,P18031,Q9Y5A9,Q7Z739,Q7Z434,Q9Y3Z3 6 +Negative regulation of type b pancreatic cell apoptotic process 0.5104183736449011 0.634214820799474 0.5259406365869828 1.0 0.8830634985864789 5 O76024,O00330,Q13247 3 +Antigen processing and presentation of peptide antigen via mhc class i 0.4142947014318068 0.632100768270091 0.5273210332224472 1.0 0.8830634985864789 10 Q9UIQ6,Q9NZ08,P10321 3 +Positive regulation of posttranscriptional gene silencing 0.3748264565824462 0.6298296016765537 0.528806076036739 1.0 0.8830634985864789 15 P51114,Q06787,Q13546,O60573,Q01085 5 +Positive regulation of isotype switching to igg isotypes 0.6506474820143855 0.6295673750933024 0.5289776745467467 1.0 0.8830634985864789 2 P43246 1 +Regulation of trans synaptic signaling 0.2815619737609702 0.6283620888388016 0.529766766349248 1.0 0.8830634985864789 62 Q4J6C6,Q9UQB8,P41440,P0DP25,P05067,Q96A49,Q92830,P05771 8 +Regulation of reactive oxygen species metabolic process 0.3183154177237227 0.6274006759811567 0.5303966247529426 1.0 0.8830634985864789 32 P30536,P00374,Q8IXJ6 3 +Negative regulation of microtubule polymerization 0.5087901024929108 0.6273540502280215 0.5304271807356669 1.0 0.8830634985864789 5 P16949,Q02790,Q14155 3 +Regulation of translation in response to endoplasmic reticulum stress 0.5479930797386205 0.6272686007276063 0.5304831820107974 1.0 0.8830634985864789 4 Q15363,Q13217 2 +Positive regulation of dna methylation dependent heterochromatin assembly 0.4302423556839078 0.6259301332253998 0.5313607687530921 1.0 0.8830634985864789 8 Q9UK61,Q8NEY8 2 +Platelet degranulation 0.6494964028776951 0.6253606181341321 0.5317344031805773 1.0 0.8830634985864789 2 P07948 1 +Cytokine production involved in immune response 0.3970534983914132 0.6251364403891806 0.5318815130951933 1.0 0.8830634985864789 11 P09601,P04439,P14174 3 +Response to x ray 0.3757879767122747 0.6201732760407942 0.5351437136793264 1.0 0.8850716386602074 14 Q70UQ0 1 +Negative regulation of response to wounding 0.4206998832820911 0.6201074235725633 0.5351870650590662 1.0 0.8850716386602074 9 Q96G23 1 +Positive regulation of endothelial cell apoptotic process 0.6588434735808103 0.619164913445782 0.5358077234265948 1.0 0.8850716386602074 3 Q53EL6 1 +Regulation of myotube differentiation 0.4747367298327682 0.6181279049136083 0.5364910291417788 1.0 0.8850716386602074 6 Q8NEZ5 1 +Regulation of gene expression by genomic imprinting 0.6583189407023505 0.6173573314376101 0.5369990592289631 1.0 0.8850716386602074 3 Q8NB78,P38398 2 +Cardiocyte differentiation 0.3349491016909717 0.616731431488752 0.5374118856782999 1.0 0.8850716386602074 24 O75844,Q92830,Q53EL6,Q9UGN5 4 +Tor signaling 0.342147219933351 0.615139193844578 0.5384628002202003 1.0 0.8850716386602074 22 O75844,O75663,Q96A49,Q96EB6,P31749 5 +Positive regulation of transcription regulatory region dna binding 0.4280685626763466 0.6150284025888275 0.5385359634126856 1.0 0.8850716386602074 8 P09874 1 +Maintenance of protein localization in organelle 0.3621292532213521 0.6147383416000542 0.5387275345227303 1.0 0.8850716386602074 18 P30536,P31749 2 +Mitochondrial outer membrane permeabilization 0.395111975996842 0.6143062841445606 0.5390129506994299 1.0 0.8850716386602074 11 P45880 1 +Protein localization to chromosome centromeric region 0.3746345552606464 0.6131489944628513 0.5397778268101425 1.0 0.8856927143369888 14 Q8NG31,Q13123,Q96EA4,Q96JM3,Q96DY7 5 +Attachment of spindle microtubules to kinetochore 0.3471087542626481 0.6100816931278455 0.5418076929879971 1.0 0.8868056682685628 21 Q96JM3,Q8IXJ6 2 +Spindle midzone assembly 0.5045279765422818 0.6094737498635083 0.5422104670502839 1.0 0.8868056682685628 5 O43663,Q9NQS7,Q9H0H5 3 +Chondroitin sulfate proteoglycan metabolic process 0.5045107085115492 0.6094015436221586 0.5422583149877127 1.0 0.8868056682685628 5 Q8N6G5 1 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.3651307083274128 0.6087009504683523 0.5427226769143796 1.0 0.8870606146355341 17 O60313,P18031,P46379,O00330,O95831,Q96EB6 6 +Response to interleukin 6 0.4725388368351843 0.6082729908197634 0.5430064313945924 1.0 0.8870606146355341 6 Q96JM3 1 +Regulation of lymphocyte activation 0.282498754221023 0.6076533293303227 0.5434174228314683 1.0 0.8873797767128984 60 O96028,O96005,P30825,P49366,Q9HCL2,Q9BXW9,Q66K64,P12956,P04439,Q5RKV6,P14174,Q96EY1,P00813,P31749,Q92830,Q96IZ0 16 +Negative regulation of cold induced thermogenesis 0.4094590084118934 0.6063735203778919 0.5442667479408447 1.0 0.8882205396985381 10 Q9UIQ6 1 +Mammary gland development 0.3409600363893831 0.606268151862636 0.5443367034910755 1.0 0.8882205396985381 22 Q99808,P31749,P31751 3 +Regulation of response to cytokine stimulus 0.3302846512914418 0.6051417557434265 0.545084811906926 1.0 0.8889345198226987 26 Q14166,P18031,Q13546,Q9Y5A9,Q8TCT8,Q7Z739,Q9UJ41,Q01804,Q9Y3Z3 9 +Digestive system process 0.377032849575603 0.604181436822342 0.5457230211767721 1.0 0.8893813966197751 12 Q16739,Q8WTV0 2 +Regulation of tube size 0.3769315762604693 0.6035904045599122 0.5461159938756608 1.0 0.8898017516436025 12 P42892 1 +Positive regulation of stress activated protein kinase signaling cascade 0.3750546973210903 0.6029059631542086 0.5465712487787893 1.0 0.8898833600700377 13 P05067 1 +Regulation of regulated secretory pathway 0.3512103981399559 0.6023179589939622 0.5469625086899166 1.0 0.8903003877860327 20 P09601,Q4J6C6,P05771 3 +Somatic diversification of immune receptors 0.3235153844893472 0.6011406889209172 0.5477462845295489 1.0 0.891111221913085 29 P43246,O96028,Q9UQ84,Q12888,O60318,Q96FV9,Q9Y3Z3,Q5RKV6,Q5UIP0 9 +Histone h4 k16 acetylation 0.4084366786442088 0.6009603772820675 0.5478663772909254 1.0 0.891111221913085 10 Q96EB6,O75844,Q03164 3 +Cellular senescence 0.334054191456773 0.5997186166277799 0.548693779053655 1.0 0.8916577526600556 23 P67809,P16104,Q96SB8,O75844,Q96IZ0 5 +Mitotic cytokinesis 0.3053591240399841 0.598289702835322 0.5496466461636333 1.0 0.8924646997467176 38 P16949,O95630,Q9Y2S7,P25054,Q9NQS7,Q13464,Q9H444,Q9H0H5,O95235,Q9Y5X1,Q6DKK2,Q9HD42,Q13432,Q9Y3E7,P37198 15 +Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.4244731694864473 0.5970801518409916 0.5504538687603897 1.0 0.8927651905887135 8 P09601,Q8IWB1 2 +Regulation of histone phosphorylation 0.4162173140310835 0.5970456417460359 0.5504769084527796 1.0 0.8927651905887135 9 O43823 1 +Negative regulation of g protein coupled receptor signaling pathway 0.448925466009463 0.5960947705344891 0.551111917500263 1.0 0.8933816009535618 7 P00813 1 +Regulation of myeloid leukocyte differentiation 0.3754258188722946 0.5948158805783845 0.5519665511009406 1.0 0.8938237873093268 12 O00165,Q04721 2 +Ribonucleoprotein complex disassembly 0.5010095381353992 0.5948019447944984 0.5519758674399227 1.0 0.8938237873093268 5 Q9UBB9,Q07866 2 +Phosphorylation of rna polymerase ii c terminal domain 0.5009156390056331 0.5944115195026887 0.5522369056243424 1.0 0.8940267742404894 5 P50750,Q9NYV4,Q8WUA2 3 +Body fluid secretion 0.3661118454053172 0.5929256724746629 0.5532308961397077 1.0 0.8940889148959503 16 Q99808,P00813 2 +Regulation of dephosphorylation 0.3066390166428063 0.592428171273747 0.5535639065142579 1.0 0.8940889148959503 36 Q9UPR3,O95429,P0DP25,Q96JB5,P78318,Q15257,Q86XL3,O75663,Q69YH5 9 +Regulation of response to dna damage stimulus 0.2730182806555801 0.5922718212381195 0.5536685821828748 1.0 0.8940889148959503 82 P51116,P16104,Q96B01,Q8N163,P50750,P38398,Q9UBB9,Q96EB6,Q7Z4V5,Q9NRR5,P35637,O95619,P51114,O96028,P09874,P14174,O75844,Q9NYF8,P61978 19 +Response to osmotic stress 0.3445040531398173 0.5912508126081689 0.5543523812832678 1.0 0.8940889148959503 21 P08183 1 +Microtubule anchoring at centrosome 0.5384570484159685 0.5903150601805423 0.554979444478708 1.0 0.8940889148959503 4 Q15154 1 +Regulation of peptide transport 0.3281478471078456 0.5879075144058002 0.5565943723810323 1.0 0.8940889148959503 26 Q8N183,O00233,P00367,P53985 4 +Crd mediated mrna stabilization 0.4143999264466316 0.5877448226680871 0.5567035849410331 1.0 0.8940889148959503 9 O60506,P67809 2 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4143999264466316 0.5877448226680871 0.5567035849410331 1.0 0.8940889148959503 9 O60506,P67809 2 +Reproductive behavior 0.5376793040328002 0.5873263621142935 0.5569845393008983 1.0 0.8940889148959503 4 P05067 1 +Mating behavior 0.5376793040328002 0.5873263621142935 0.5569845393008983 1.0 0.8940889148959503 4 P05067 1 +Embryonic hemopoiesis 0.4987625816757322 0.5854757777353559 0.5582278489751338 1.0 0.8950720083905993 5 Q9H6E4 1 +Negative regulation of protein containing complex assembly 0.3016395518551231 0.584541328399055 0.5588561683089093 1.0 0.8950720083905993 40 P16949,Q9NYL9,Q8IXJ6,P45880,P28289,Q9UBB9 6 +Embryonic brain development 0.4671382060506856 0.5841977341501352 0.5590872858048921 1.0 0.8950720083905993 6 P62995 1 +Cytokinesis 0.2686706187322041 0.5829329532224301 0.559938435956779 1.0 0.8950720083905993 68 O43663,P16949,O95630,Q9Y2S7,P25054,O75400,P0DP25,Q9H444,O95235,Q96C92,O75935,Q9HD42,Q6DKK2,P41208,Q13432,Q15058,P37198,Q12768 18 +Negative regulation of cellular senescence 0.4976087469576322 0.5807002523874227 0.5614424915970766 1.0 0.8950720083905993 5 P67809 1 +Nucleoside triphosphate catabolic process 0.4662060163886508 0.580063070475307 0.5618720863764382 1.0 0.8950720083905993 6 P00813,Q9H773 2 +Deoxyribonucleoside triphosphate catabolic process 0.4662060163886508 0.580063070475307 0.5618720863764382 1.0 0.8950720083905993 6 P00813,Q9H773 2 +Amino acid salvage 0.6466696628984436 0.5776103851757448 0.5635271938855781 1.0 0.8950720083905993 3 Q13126 1 +L methionine salvage from methylthioadenosine 0.6466696628984436 0.5776103851757448 0.5635271938855781 1.0 0.8950720083905993 3 Q13126 1 +Nuclear ncrna surveillance 0.4655718813022027 0.5772540304756716 0.563767862573765 1.0 0.8950720083905993 6 Q13868,Q06265,Q9NQT5,Q01780,Q96B26 5 +Response to ischemia 0.403822123386798 0.576645756841546 0.5641787823007807 1.0 0.8950720083905993 10 O95831 1 +Negative regulation of sequestering of triglyceride 0.6359712230215799 0.5766128177263079 0.5642010384612304 1.0 0.8950720083905993 2 Q9BZF1 1 +Negative regulation of lipid storage 0.6359712230215799 0.5766128177263079 0.5642010384612304 1.0 0.8950720083905993 2 Q9BZF1 1 +Regulation of triglyceride catabolic process 0.6359712230215797 0.5766128177263059 0.5642010384612317 1.0 0.8950720083905993 2 Q8NCG7 1 +Positive regulation of triglyceride catabolic process 0.6359712230215797 0.5766128177263059 0.5642010384612317 1.0 0.8950720083905993 2 Q8NCG7 1 +Triglyceride catabolic process 0.6359712230215797 0.5766128177263059 0.5642010384612317 1.0 0.8950720083905993 2 Q8NCG7 1 +Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4121507205648202 0.5762751307120089 0.5644292297560995 1.0 0.8950720083905993 9 Q96EB6,P31749,Q15233,Q9UL15 4 +Regulation of hormone secretion 0.3181174023208467 0.5760658740977064 0.5645706567642677 1.0 0.8950808607843501 30 O00233,Q6ZWJ1,Q8N183,P53985,P00367 5 +Glycosphingolipid metabolic process 0.4035437414233125 0.5751853559027995 0.5651659456401703 1.0 0.8954952525930471 10 P06865,Q99805,Q16739 3 +Negative regulation of protein serine threonine kinase activity 0.3281822522452473 0.5750762100764859 0.5652397564933196 1.0 0.8954952525930471 25 P18031,P25054,Q96JB5,Q53EL6,Q96EB6,P31749,P37198 7 +Endothelial cell migration 0.2992737960279025 0.5740455051163393 0.5659370084289521 1.0 0.896133560210286 41 P06576,Q8WTV0,P09601,P31749,P42785 5 +Negative regulation of histone h3 k9 trimethylation 0.6455039986888371 0.5736765844068868 0.5661866764540022 1.0 0.896133560210286 3 Q96EB6 1 +Type b pancreatic cell apoptotic process 0.464259529528471 0.5714501121716561 0.5676945682145393 1.0 0.8976096558601402 6 O76024,Q13247,O00330,P20810 4 +Regulation of cell activation 0.2695687055729781 0.5705051982137669 0.5683350974431911 1.0 0.8978086686773402 73 O96028,Q15418,P30825,P49366,Q66K64,P12956,Q5RKV6,P14174,P09601,P00813,P31749,Q92830,Q96IZ0 13 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.3673624876712302 0.5692091323207418 0.569214223876223 1.0 0.8981783630729846 14 P05067,P14174 2 +Multicellular organism reproduction 0.246396505360347 0.5690177056541688 0.569344124327485 1.0 0.8981783630729846 136 Q9UPN4,P46379,Q8IXJ6,P16104,O75718,Q9Y5A9,Q96EB6,Q12768,Q14320,Q9BQE5,Q08J23,Q15067,Q96PU8,Q9BXW9,P00813,P31749,Q15363,O95394,Q01085,Q9BTX1,Q7Z7E8,Q96EP5,Q9H2V7,O95453,P42575,P41208,Q8IZL8,Q07666,P05067 29 +Platelet derived growth factor receptor beta signaling pathway 0.6333812949640257 0.567428255880197 0.5704232571757788 1.0 0.8989521266518073 2 P18031 1 +Regulation of wound healing 0.3618671561800433 0.5662757683204236 0.5712063302273571 1.0 0.8993258088095714 16 Q16625 1 +Apoptotic process involved in development 0.4627367787194049 0.564731868086695 0.5722561548557603 1.0 0.8996888103900273 6 P30154,O75312 2 +Heparan sulfate proteoglycan metabolic process 0.4930164884971109 0.5617876131308095 0.5742607325896512 1.0 0.8999808103723851 5 Q99805,Q96L58 2 +Heparan sulfate proteoglycan biosynthetic process 0.4930164884971109 0.5617876131308095 0.5742607325896512 1.0 0.8999808103723851 5 Q99805,Q96L58 2 +Regulation of epidermal growth factor activated receptor activity 0.4618700375250716 0.5609157587622888 0.5748549665826437 1.0 0.8999808103723851 6 P22681,P05067 2 +Deoxyribose phosphate catabolic process 0.4168577509315239 0.5594283234032941 0.5758694358918075 1.0 0.8999808103723851 8 P00813,Q9H773 2 +Rna capping 0.4922097276181013 0.55848095666725 0.5765160047850393 1.0 0.8999808103723851 5 Q53F19 1 +Poly a plus mrna export from nucleus 0.3846865898602455 0.5567900741792116 0.5776708663229104 1.0 0.8999808103723851 11 O60318,P82979,Q96ST2,Q8N1F7 4 +Positive regulation of rna metabolic process 0.2831955019511584 0.5566566876355228 0.5777620147679767 1.0 0.8999808103723851 374 P18615,Q8IXJ6,Q96EB6,Q92905,Q86V81,Q5VTR2,P98179,Q14011,Q9H1E3,Q92841,P38159,Q96PK6,Q96HY6,Q9NPJ6,P51812,P23246,Q15418,P35637,Q9H7Z7,Q92804,Q9UER7,P09874,O75312,Q9UPP1,O95453,Q15427,P05067,P05771,P53999,Q8N163,Q9ULX6,Q03164,P50750,P38398,P19338,P12956,Q86U70,P51858,Q96L73,Q969T7,Q99729,O00165,P62995,P31749,P37198,Q96E39,Q92830,Q92945,O60869,Q96I24,P61978,O60506,Q9H7B4,Q9Y5A9,Q8NCF5,Q13595,P41440,P82970,Q9NY61,Q6Y7W6,O00233,Q969G3,Q9NPI1,Q9H2V7,Q8IZL8,Q9NYF8,Q9Y2W1,P04150,Q13501,Q13148,P61457,Q9BRT9,Q9HB09,P67809,Q9BVS4,Q8N7H5,O95619,Q86VM9,Q6PL18,Q13546,Q96JB5,Q96EP5 82 +Regulation of necrotic cell death 0.3686842883495722 0.5558463609505979 0.578315889325365 1.0 0.8999808103723851 12 P30536,Q13546 2 +Positive regulation of histone h3 k9 acetylation 0.6401812993438042 0.555819216183391 0.5783344476395804 1.0 0.8999808103723851 3 P38398 1 +Regulation of endocytosis 0.2839259022708872 0.5550985991193349 0.5788272209303018 1.0 0.8999808103723851 54 Q06787,P18031,P41440,Q99816,P0DP25,Q9UJ41,Q9UKG1,Q96T51,Q13432,P22681,Q8N6T3,Q96PU5,Q2M2I8,P05067,P50897,P61978,Q6UWE0 17 +Positive regulation of small molecule metabolic process 0.356764471348918 0.5548197497673546 0.5790179569700551 1.0 0.8999808103723851 17 P31751,P31749,P05067 3 +Rna localization 0.2549490359573579 0.554614522658085 0.5791583534348228 1.0 0.8999808103723851 126 Q07955,Q96HR8,Q8TD16,Q9ULX6,P35658,P52948,O60318,Q96FV9,Q9H814,Q86V81,P22626,Q96MU7,Q99729,Q9UPR3,P49790,P41440,Q08J23,Q16629,P49792,P09651,Q96PU8,Q96ST2,Q8NFH4,Q53F19,P37198,P67809,Q06787,Q99567,Q9BVL2,Q6I9Y2,O15504,Q9BZI7,Q9BTX1,Q92945,Q8N1F7,Q86U42,O95453,Q8WWY3,P51991,P57740,P41208,Q07666,P82979 43 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.3565489506122541 0.5534440249852125 0.5799593996870023 1.0 0.8999808103723851 17 P09874,Q04721,P33981,Q14318,Q8N1F7 5 +Regulation of dendrite extension 0.5287168001630851 0.5531778241143194 0.5801416504091392 1.0 0.8999808103723851 4 Q96PU5,Q9Y263 2 +Regulation of t cell activation 0.2982691331360135 0.5509092620126741 0.5816958779391599 1.0 0.9013437260829996 40 O96005,P30825,P49366,Q9HCL2,Q9BXW9,P04439,Q96EY1,P00813,P31749,Q92830,Q96IZ0 11 +Regulation of pinocytosis 0.5272950336267231 0.5478119605938456 0.5838210250953826 1.0 0.9017338805329292 4 P50897 1 +Positive regulation of pinocytosis 0.5272950336267231 0.5478119605938456 0.5838210250953826 1.0 0.9017338805329292 4 P50897 1 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.5266797335776696 0.5454942782118237 0.5854136147215512 1.0 0.9032565331846072 4 P14174 1 +Positive regulation of immune system process 0.2551384860348942 0.543683684252618 0.5866591618795853 1.0 0.9043451761823932 125 P46379,P49366,P12956,P04439,Q96EY1,Q96EB6,O60828,O00165,Q9UKG1,Q9HCL2,Q07021,P00813,Q96PK6,P31749,Q04721,P23246,P30825,P09601,P43243,Q15233,Q96IZ0,O96028,Q13546,Q5RKV6,P14174,Q8WXF1,Q07666,P05067,P05771 29 +Negative regulation of natural killer cell mediated immunity 0.6358597734968527 0.5414514291545023 0.5881964671408202 1.0 0.9051215621244084 3 P46108 1 +Intraciliary transport 0.4048835881957826 0.5395448525689833 0.5895109570521604 1.0 0.9054756056895308 9 Q9UPN4,O43805,Q15154 3 +Histone h4 acetylation 0.322093703145803 0.5395002663771687 0.5895417132202287 1.0 0.9054756056895308 26 O75844,Q03164,Q5T5X7,P38398,Q86UY6,Q96EB6,O95619,Q92830 8 +Protein containing complex disassembly 0.2667795431622098 0.537923716627791 0.5906297141742711 1.0 0.9065127385730892 104 Q9NRR5,P16949,P25054,Q9NYL9,Q969G3,O75381,Q9Y3E1,O95721,Q9H444,P35611,P48681,Q9ULW0,P28289,Q9UBB9,Q86Y91,Q9HD42,O75844,Q01105 18 +Segmentation 0.3571230852661278 0.5367715637236924 0.5914254163195853 1.0 0.9066426820890572 16 Q15363,Q92830,O94788 3 +Positive regulation of cell growth 0.2909673924771997 0.5355983185196707 0.5922361911148513 1.0 0.9066436248832552 44 Q15418,O95684,P51812,Q9UGN5 4 +Regulation of rna binding 0.4040192494610718 0.5352112521029738 0.5925037864239333 1.0 0.9066436248832552 9 Q86X55,P50750,Q9H1E3 3 +Response to arsenic containing substance 0.3644020541592002 0.5313799128877089 0.5951555383537463 1.0 0.9081471308803052 12 P36551,Q9BXP5,Q9BWF3,P09601,Q9UER7 5 +Humoral immune response 0.3604398302418324 0.5279887730701287 0.5975071282365771 1.0 0.9081471308803052 14 Q04721,Q9UQ84,Q9Y5A9,Q96JM3,Q07021 5 +Regulation of xenophagy 0.6316576204989323 0.5275968747819176 0.5977791625872384 1.0 0.9081471308803052 3 Q6UWE0 1 +Isotype switching to igg isotypes 0.6315486470926774 0.5272391474267827 0.5980275264557757 1.0 0.9081471308803052 3 P43246,Q96QE3 2 +Regulation of retrograde protein transport er to cytosol 0.621870503597119 0.5272350445049618 0.5980303753146776 1.0 0.9081471308803052 2 Q9GZP9 1 +Developmental maturation 0.2837570884470867 0.527207413307718 0.598049561164224 1.0 0.9081471308803052 50 Q8IXJ6,Q08J23,Q9Y5A9,Q9Y5Y0,P05067,O94788 6 +Copper ion transport 0.6312607944732188 0.5262945961916758 0.5986835370136234 1.0 0.908504335647804 3 P35670,Q8N4V1 2 +Axon development 0.2683637570085603 0.5246680238075813 0.5998139897825019 1.0 0.9091515409019372 83 P16949,Q9UQB8,Q04721,P00374,P41440,P30536,P42892,Q96G23,P05067,O00264 10 +Membrane organization 0.2706862716932142 0.5219775725510198 0.6016859459925543 1.0 0.9097913925853252 245 Q7Z3C6,P46379,Q8IXJ6,O15228,Q9ULX6,Q9NS69,P42356,Q9P0J0,Q86XL3,Q13148,Q13505,P20700,P08183,Q15070,P02545,P41440,P30536,Q9H444,O43681,O15118,Q9HD42,Q8NHH9,P31749,P31751,Q15363,Q9UQB8,O14976,Q16739,Q15392,Q3ZCQ8,P45880,Q9UBV8,Q9Y2U8,Q8N6H7,Q5SQN1,P98194,O95721,Q8N1F7,Q9UII2,O43765,P0DP25,Q9NX63,O14737,Q9Y512,Q15629,Q9UH99,O75844,P33527,Q9P2W9,P50897,P05771 51 +Membrane depolarization 0.3610827239790095 0.5209868895823607 0.6023759044102286 1.0 0.9099162847682248 13 Q9UII2,P09874,P30536 3 +Regulation of t cell mediated immunity 0.4524639828368635 0.5198882489401719 0.603141466172181 1.0 0.9100010606152557 6 P04439 1 +Positive regulation of vacuole organization 0.4825554479166661 0.5193002286649302 0.6035513939445998 1.0 0.9100010606152557 5 Q8TBX8 1 +C4 dicarboxylate transport 0.4319754874892441 0.5181022738851132 0.6043869138240061 1.0 0.910069596894709 7 Q9UJS0,O75746,Q9UBX3 3 +Negative regulation of sodium ion transport 0.4821377472726006 0.5176218861951264 0.6047221085178687 1.0 0.910069596894709 5 P46934 1 +Labyrinthine layer morphogenesis 0.5191007399982303 0.5171764830683188 0.6050329669039316 1.0 0.910069596894709 4 Q15363,O75190 2 +Regulation of transcription involved in g1 s transition of mitotic cell cycle 0.5190724007902584 0.5170714182367429 0.605106304813581 1.0 0.910069596894709 4 O75312 1 +Regulation of epithelial cell apoptotic process 0.3618444260494579 0.5168813020987404 0.6052390208134537 1.0 0.910069596894709 12 Q13247,Q53EL6,O00330,P09601,Q4KMQ2,O76024 6 +Regulation of receptor mediated endocytosis 0.3109615031470061 0.5148815977233188 0.606635760949483 1.0 0.9115445903982082 30 P41440,Q13432,P05067,P50897,P61978 5 +Mitochondrial calcium ion homeostasis 0.3768030645068929 0.5140933372730334 0.6071867354376572 1.0 0.9116647513113814 11 Q8WWC4,Q9Y3D6,Q9Y4W6,Q8IYU8,Q9BPX6,Q16891 6 +Pinocytosis 0.407392743696048 0.513392742521495 0.6076766212344324 1.0 0.9116647513113814 8 P50897 1 +Negative regulation of receptor mediated endocytosis 0.3612032107458324 0.5132603335940892 0.607769227022724 1.0 0.9116647513113814 12 P05067 1 +Response to growth hormone 0.4507910303388832 0.5126687184198307 0.6081830750051433 1.0 0.9116647513113814 6 P18031,P31749 2 +Plasma membrane repair 0.3914515546865103 0.5125179077135971 0.6082885905349091 1.0 0.9116647513113814 10 Q9HD42 1 +Protein localization to phagophore assembly site 0.4805401564440887 0.5112161067544906 0.6091997415177279 1.0 0.9116647513113814 5 Q9Y4P1 1 +Muscle tissue development 0.2746123827673839 0.5104278369754759 0.6097517588667509 1.0 0.9116647513113814 60 Q04721,P02545,P41440,Q8IXJ6,Q8NEZ5,Q9BYT8,Q9UGN5,O75844,Q92830,O94788 10 +Replication fork processing 0.3606545070375959 0.5101663030703818 0.6099349575063975 1.0 0.9116647513113814 12 Q9NVH0,P50750,Q9H1E3,Q9Y3Z3,Q14191,Q86V81 6 +Lipid modification 0.281127931370598 0.5085294440468235 0.6110820954692988 1.0 0.9116647513113814 52 P31751,Q13011,O75521,Q16134,Q15067,P23786,O14734,P31749,P34913 9 +Vacuole organization 0.2783692558877601 0.5085242228007242 0.6110857561348189 1.0 0.9116647513113814 56 Q96ED9,P11117,Q9UNZ2,Q9Y4P1,Q14108,Q9H444,Q6UWE0,O75503,Q8N511,Q8TBX8,O75787,Q9P253,P50897,Q7Z3C6,Q12768,P54802 16 +Regulation of neuron migration 0.4298057362913078 0.5083007306897723 0.6112424577000828 1.0 0.9116647513113814 7 O43379,Q9Y4G8 2 +Positive regulation of t cell mediated cytotoxicity 0.5165094428765096 0.5075955749248876 0.6117369945612177 1.0 0.9117247358434434 4 P04439 1 +Regulation of t cell mediated cytotoxicity 0.5165094428765096 0.5075955749248876 0.6117369945612177 1.0 0.9117247358434434 4 P04439 1 +Regulation of membrane repolarization 0.4494623199151978 0.5069522605231251 0.6121883155378582 1.0 0.9119848091971396 6 O75844 1 +Cd40 signaling pathway 0.478893462750402 0.5046359937143678 0.6138145242903641 1.0 0.9132971022846128 5 Q9BXW9 1 +Long term synaptic depression 0.624464107355464 0.5041566812135321 0.6141512785939127 1.0 0.9132971022846128 3 Q06787 1 +Synaptic vesicle docking 0.6146762589928025 0.50266238584822 0.6152016593957657 1.0 0.9142002105905954 2 O14795 1 +Regulation of mitotic cell cycle 0.2445726554200986 0.502192278779682 0.6155322737167146 1.0 0.9142325020254024 149 O75150,Q9Y2S7,Q8IXJ6,P50750,P38398,Q13123,Q06323,Q9UJX3,Q96EB6,Q69YH5,Q5VTR2,P25054,Q9Y619,Q9UKG1,Q9UL46,Q9BXW9,P61289,P31749,Q15058,P37198,Q6NUQ1,Q9NYL9,Q9NY61,Q96EA4,Q9BVS4,Q96DY7,Q6Y7W6,Q14166,Q96JB5,Q9NPI1,P42575,Q9UJX2,Q9NVM9,Q9HAW4,O75844,P05067,Q96BK5 37 +Response to uv a 0.6238173115025119 0.5020667238531032 0.6156205865075441 1.0 0.9142325020254024 3 P31749 1 +Negative regulation of leukocyte cell cell adhesion 0.3559039994538981 0.5013375421015724 0.6161335881941128 1.0 0.9147598496194252 14 P31749 1 +Myeloid leukocyte activation 0.3182872879464397 0.4979074404592364 0.6185492827744827 1.0 0.9172645898685746 25 P22681,Q96JM3,P14174,P09601,P05067 5 +Retinol metabolic process 0.4040260017760921 0.4972405405921427 0.619019435977632 1.0 0.9173907025768372 8 O94788 1 +Negative regulation of sodium ion transmembrane transport 0.5135064664201755 0.4965596122868666 0.6194996398807362 1.0 0.9174832832488584 4 P46934 1 +Midbrain development 0.3202575786734191 0.4952060291498776 0.6204546951713359 1.0 0.9182785234689874 23 Q8IXJ6,P0DP25,Q16352,Q92830,P00367 5 +Immune response regulating cell surface receptor signaling pathway 0.2955107011626061 0.4943212444510333 0.6210793238954713 1.0 0.9187902256729368 37 P46379,Q9UJ41,Q9UKG1,Q07666,P04439,P00813,Q96IZ0,P05771 8 +Positive regulation of chromatin organization 0.3729149614699164 0.4933177520285038 0.621788087028257 1.0 0.9190133928733032 11 Q8NEY8,Q9UK61,Q6VMQ6 3 +Neural crest formation 0.4758439319850098 0.4925119642169644 0.6223574661715634 1.0 0.919314788555439 5 Q9UBV8 1 +Production of molecular mediator of immune response 0.293417318041904 0.4921720201089632 0.6225977424787206 1.0 0.919314788555439 39 P43246,O96028,Q9UQ84,Q12888,Q7Z434,O60318,P04439,Q96FV9,Q9Y3Z3,P14174,P09601,Q96EB6,Q5RKV6,Q5UIP0 14 +Maintenance of protein location in cell 0.3187809706886579 0.4920618333296664 0.6226756323585128 1.0 0.919314788555439 24 P30536,P31749 2 +Protein localization to endoplasmic reticulum exit site 0.5122713971672317 0.4920420474131791 0.6226896192628508 1.0 0.919314788555439 4 Q5JRA6,O15027 2 +Regulation of monocyte chemotaxis 0.4456928838951182 0.4908217683804692 0.6235525123231285 1.0 0.9195256644470232 6 Q8NHP6,O94813,P09429,Q4KMQ2,P07948 5 +Leukocyte tethering or rolling 0.511373452346682 0.4887655187135135 0.625007712369926 1.0 0.920468443631078 4 Q13464,P35612,Q9H4A6 3 +Mrna modification 0.3511278903767461 0.4854401890854105 0.6273641299854833 1.0 0.9217458642866952 15 Q8IZ73,Q99729,Q15007,Q08J23 4 +Protein depolymerization 0.2805453342272819 0.4847557443060737 0.6278496189621046 1.0 0.9217458642866952 48 P16949,P25054,Q9NYL9,Q9Y3E1,P35611,P48681,P28289,Q86Y91,Q9ULW0 9 +Protein localization to cytoskeleton 0.3188485862947167 0.4847342914506181 0.6278648384626946 1.0 0.9217458642866952 23 P25054,Q9UPN4,Q9UNZ2,Q14789,Q15154,P33981,Q13561,Q96JM3,P37198 9 +Erythrocyte development 0.4012443609845041 0.4839897500560222 0.6283931434778927 1.0 0.9217458642866952 8 Q9Y5Y0 1 +Skeletal system morphogenesis 0.3419016145356892 0.4825799208782811 0.6293940388928347 1.0 0.9220568938296 18 O75844,Q92896,Q9Y5Y0 3 +Antifungal innate immune response 0.608345323741004 0.4814085625233352 0.6302261522852133 1.0 0.9220568938296 2 Q9Y4E8 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.9220568938296 3 P10321 1 +Neutral lipid catabolic process 0.5090699683271059 0.4803911888010682 0.630949258465973 1.0 0.9220568938296 4 Q8NCG7,Q96AD5,Q8N2K0 3 +Regulation of establishment of protein localization to mitochondrion 0.3180666138415099 0.4789405598937099 0.6319809153096569 1.0 0.9220568938296 23 P55786,Q9UII2,O95429,O00165,Q96EP0,O14737,O43464 7 +Negative regulation of signal transduction in absence of ligand 0.4229104983115176 0.4774576956641952 0.633036238309975 1.0 0.9220568938296 7 P31749,Q13546 2 +Regulation of glucan biosynthetic process 0.4423913436782112 0.4768021084137201 0.6335030442201546 1.0 0.9220568938296 6 P31749 1 +Regulation of glycogen metabolic process 0.4423913436782112 0.4768021084137201 0.6335030442201546 1.0 0.9220568938296 6 P31749 1 +Spliceosomal complex assembly 0.2881828714470942 0.4762430724435608 0.6339012168147773 1.0 0.9224326673128462 42 Q16637,Q07955,Q9UHX1,P52756,Q13242,O95391,O75494 7 +Double strand break repair 0.2636267137866102 0.475706868850705 0.634283226697058 1.0 0.9225810553436896 101 P16104,Q96B01,P38398,P12956,O94761,Q9UBB9,P33991,Q9BRT9,Q9H1E3,Q9BXW9,Q7Z4V5,Q9UGN5,Q9Y3Z3,Q9NRR5,P23246,P35637,O95619,O96028,P09874,Q96SB8,Q14566,Q14191 22 +Negative regulation of cell cell adhesion 0.3174644183099385 0.474487710573628 0.6351521595429688 1.0 0.9231965485855912 23 P31749,Q96IZ0 2 +Regulation of phosphoprotein phosphatase activity 0.3439844958029653 0.4744529312437245 0.6351769552577367 1.0 0.9231965485855912 17 O75663,Q15257,P0DP25 3 +Positive regulation of neuron migration 0.4416295726831961 0.4735821408459445 0.6357979133609581 1.0 0.9233392212618392 6 O43379,Q9Y4G8 2 +Fatty acid alpha oxidation 0.605467625899277 0.4718666433737451 0.6370219786048419 1.0 0.92397414735182 2 A1L0T0 1 +Cohesin loading 0.5061054057522358 0.4696801170851836 0.6385835752985951 1.0 0.9250552277460492 4 Q7Z5K2 1 +Regulation of mitotic cell cycle phase transition 0.2616627418446494 0.4695847428161816 0.6386517272752736 1.0 0.9250552277460492 106 Q8IXJ6,P38398,Q06323,Q13123,Q9NZJ0,Q9UJX3,P25054,Q9Y619,Q9UKG1,Q9UL46,P61289,P31749,Q15058,Q6NUQ1,Q9NYL9,Q96EA4,Q9BVS4,Q96DY7,Q6Y7W6,Q96JB5,Q9NPI1,P42575,Q9UJX2,Q9HAW4,P05067,Q96BK5 26 +Digestion 0.3519643626022848 0.4689493791504674 0.6391058195310033 1.0 0.9251028657490732 13 Q8WTV0 1 +Myelin maintenance 0.4404437665815547 0.4685810660279428 0.6393691136363859 1.0 0.9252807137601904 6 P31749 1 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.3003124984109264 0.4673377460064074 0.6402582548884315 1.0 0.925608525271756 32 P09874,Q04721,Q13573,Q8N0X7,Q9UNE7,P33981,Q9Y2U8,P62942,Q96EB6,Q14318,Q92896,Q8N1F7 12 +Regulation of actin nucleation 0.4201937175556979 0.4654388540229587 0.6416172153704935 1.0 0.926499196159584 7 P53367 1 +Carbohydrate homeostasis 0.278202629613774 0.46226516297741 0.6438911786638135 1.0 0.9281555406291548 49 Q6ZWJ1,Q99808,Q8N183,Q15043,P49366,P53985,Q9HCD5,P62995,Q96EB6,P31749,P42785 11 +Regulation of production of molecular mediator of immune response 0.3103575073451463 0.4599090595497516 0.6455814971552549 1.0 0.9290150780682812 27 P43246,O96028,Q12888,Q7Z434,P04439,Q96FV9,P14174,P09601,Q96EB6,Q5RKV6,Q5UIP0 11 +Positive regulation of transmembrane transport 0.2908114793422318 0.4580026729049405 0.646950520947686 1.0 0.9290150780682812 38 P31751,P08183,P31749,Q16625 4 +Hepaticobiliary system development 0.2897961044509922 0.4573450663959054 0.6474230421835216 1.0 0.9290150780682812 39 Q15418,P00813,O75844,O94788 4 +Regulation of post translational protein modification 0.6096157706974441 0.4569506938897058 0.6477064855846417 1.0 0.9290150780682812 3 O75718 1 +Cellular iron ion homeostasis 0.3460844059569613 0.4557624380081134 0.6485608175260225 1.0 0.9290150780682812 15 Q15904,Q15043,Q8N511,Q9Y5Y0,P09601 5 +Response to iron ion 0.4373468828237404 0.4555860176164211 0.648687699698677 1.0 0.9290150780682812 6 P09601 1 +Muscle cell apoptotic process 0.345959478045089 0.4550327493539991 0.6490856783275862 1.0 0.9290150780682812 15 P09601,P98175,Q53EL6 3 +Protein targeting to vacuole 0.3406744531384122 0.4540771438103851 0.6497733033983171 1.0 0.9290150780682812 17 Q99523,Q14108,P46934 3 +Cellular response to uv 0.3058729817357792 0.4539998970125639 0.6498289009197054 1.0 0.9290150780682812 29 P09874,P46934 2 +Negative regulation of myosin light chain phosphatase activity 0.599712230215824 0.4530132545647292 0.6505391972291568 1.0 0.9290150780682812 2 Q13464 1 +Regulation of myosin light chain phosphatase activity 0.599712230215824 0.4530132545647292 0.6505391972291568 1.0 0.9290150780682812 2 Q13464 1 +Negative regulation of bicellular tight junction assembly 0.599712230215824 0.4530132545647292 0.6505391972291568 1.0 0.9290150780682812 2 Q13464 1 +Negative regulation of cell killing 0.5014121934180699 0.4528810714844654 0.6506343816244957 1.0 0.9290150780682812 4 P46108 1 +Epithelial cell apoptotic process 0.3473375834800755 0.4518607329298656 0.6513693141285315 1.0 0.9290150780682812 14 Q13247,Q53EL6,O00330,P09601,Q4KMQ2,O76024 6 +Negative regulation of chromatin binding 0.5010069455776472 0.4514397859371483 0.6516726138756039 1.0 0.9290150780682812 4 O14981 1 +Glucosamine containing compound metabolic process 0.4652521681453107 0.4510577725171786 0.6519479111883553 1.0 0.9290150780682812 5 O60502 1 +Negative regulation of cytoskeleton organization 0.2770906103107536 0.4502266713362514 0.6525470066560113 1.0 0.9296502112122071 49 P16949,P25054,Q9NUQ9,Q9NYL9,Q9Y3E1,P35611,P38398,Q9ULW0,P28289,Q9UHB6,Q96PK6,Q92830 12 +Vasculature development 0.2603937163629515 0.4499815023090749 0.6527237784639948 1.0 0.9297010324901128 106 Q15363,Q96AY3,Q04721,P06576,Q9H6E4,Q9P266,Q53EL6,Q96PU8,Q05682,Q96JM3,Q9Y5Y0,P09601,P31749,O94788,P42785,Q9NZ08,P05771 17 +Positive regulation of translation 0.2633358596827456 0.4495646972213614 0.6530243480870732 1.0 0.929928123956284 65 O60506,P51114,P98179,Q14011,P08670,Q9Y5A9,Q9Y2R0,Q07666 8 +Excretion 0.4356470332812999 0.4484945432571474 0.6537963234361179 1.0 0.9302232725373744 6 P09601 1 +Regulation of protein tyrosine kinase activity 0.3422048568740753 0.446211093625244 0.6554447702134296 1.0 0.9321661107136388 16 O95684,P05067 2 +Adipose tissue development 0.363628877014344 0.4445326555474066 0.6566575246244111 1.0 0.9323202381239616 11 P35610,Q96EB6,Q8N0X7,O15173 4 +Inflammatory response 0.2617188996163832 0.4443457583969976 0.6567926231065186 1.0 0.9323202381239616 78 Q04721,Q9BQE5,Q13546,Q13151,P28070,Q53EL6,P31749,Q9BXW9,Q86UT6,P14174,P09601,P00813,P33527,P05067,P42785 15 +Mrna cleavage 0.3486910742955397 0.4438143089447096 0.6571768422934849 1.0 0.9323202381239616 12 Q8N684,Q6UN15 2 +Midbody abscission 0.3632101281324181 0.4423622007093947 0.6582271271631488 1.0 0.9323202381239616 11 Q9HD42,O95235,Q9H444,Q9Y3E7 4 +Ion homeostasis 0.2545802679913552 0.4403681691116899 0.6596704751683133 1.0 0.9326497668967172 117 Q8NEW0,P09874,P30519,P06576,P0DP25,Q15043,P30536,O75503,Q9Y3D6,Q9HD20,Q9Y5Y0,P09601,P05067,P50897,P05771 15 +Myotube cell development 0.4622870935199368 0.4396453730016726 0.6601939729680906 1.0 0.93288505626982 5 Q9H7B4 1 +Multicellular organism aging 0.3625274175736608 0.4388292915240016 0.6607852343013934 1.0 0.933514989024846 11 O75844,Q14191,Q9UGP8 3 +Negative regulation of nucleobase containing compound metabolic process 0.2762174767679645 0.4360689811357939 0.6627866817640067 1.0 0.934695643577875 320 O75150,P18615,Q8IXJ6,Q96EB6,Q5VTR2,Q14011,P38159,Q01105,P46934,P23246,P35637,Q92804,Q6PJT7,Q9UER7,Q15233,P45973,P09874,O95453,O75844,P82979,P78318,P53999,Q8IXH7,Q96HR8,Q8N163,Q03164,P50750,P38398,P12956,Q86U70,Q9H814,Q9NYB0,P51858,Q96MG7,Q96L73,Q96EY1,Q00577,P22626,Q5PSV4,Q99729,O75381,Q5T5X7,Q01130,Q96IZ0,Q8NEY8,O96028,Q13242,Q07666,P61978,O60506,Q9UBB9,Q96JN0,P98175,P41440,Q08J23,Q07021,O14981,Q9NRR5,O75494,Q8WXF0,Q969G3,Q9NPI1,Q8WXF1,Q9NYF8,Q9Y2W1,P04150,Q9P0J0,Q13501,Q13148,Q13151,Q53EL6,P27544,P67809,Q04721,O95983,Q8N7H5,Q9HCD5,Q96BK5 78 +Epithelial to mesenchymal transition 0.3100330052811825 0.4350861557040641 0.6634998919891018 1.0 0.934695643577875 25 Q99729,Q53EL6,Q92841,Q9UBV8,Q9UK61 5 +Long term synaptic potentiation 0.3458593294232107 0.4348376522477592 0.6636802726625857 1.0 0.934695643577875 13 P05067 1 +Endosome transport via multivesicular body sorting pathway 0.345595848288021 0.4333796316584657 0.6647389953546683 1.0 0.934695643577875 13 Q9HD42,Q9H444 2 +Multivesicular body sorting pathway 0.345595848288021 0.4333796316584657 0.6647389953546683 1.0 0.934695643577875 13 Q9HD42,Q9H444 2 +Membrane raft organization 0.3755767428990607 0.4328577333097339 0.66511812778948 1.0 0.934695643577875 10 P50897,P41440 2 +Ether biosynthetic process 0.4603699110985259 0.4323132391810374 0.665513766202324 1.0 0.9347955608230848 5 O15228 1 +Regulation of camp mediated signaling 0.5925179856115075 0.4298934724479669 0.6672731340045839 1.0 0.9360576282640416 2 Q9Y4G8 1 +Negative regulation of peptide secretion 0.3887866488897374 0.4257770986370287 0.6702702760636092 1.0 0.9383668994189583 8 Q8N183 1 +Positive regulation of t cell mediated immunity 0.4586428986595416 0.4257406320485002 0.6702968510337379 1.0 0.9383668994189583 5 P04439 1 +Negative regulation of hydrolase activity 0.2577479178724056 0.4255133431188326 0.6704624967892796 1.0 0.9383668994189583 70 Q9UII2,Q15363,P51812,O95429,Q99523,Q15418,Q9HB09,Q15043,Q15392,Q92530,Q15257,Q4VCS5,O75663,P31749,P05067 15 +Meiotic cell cycle checkpoint signaling 0.5992461655699626 0.4249965319441509 0.6708392028985233 1.0 0.9383668994189583 3 Q08J23 1 +Glucocorticoid metabolic process 0.4929455801900445 0.4230866467164778 0.6722320445835828 1.0 0.9383668994189583 4 P51608,Q04917,Q9UNE7 3 +Vacuolar localization 0.3381220848733618 0.4220929821428933 0.672957150137971 1.0 0.9383668994189583 16 P09601,P22681,Q9H0B6 3 +Non lytic viral release 0.3726891809701479 0.4187326531039293 0.6754115289238563 1.0 0.9383668994189583 10 Q9HD42 1 +Positive regulation of cell division 0.3414271733624004 0.4184427628660337 0.6756234265306447 1.0 0.9383668994189583 14 P67809,Q9Y2S7,P37198,Q8IXJ6 4 +Negative regulation of calcium ion transport 0.3725662512271607 0.4181340115334115 0.6758491390747086 1.0 0.9383668994189583 10 P21796 1 +Neurotransmitter receptor internalization 0.5884892086330902 0.4171710308775913 0.6765533128216945 1.0 0.938653317522555 2 Q14160 1 +Postsynaptic neurotransmitter receptor internalization 0.5884892086330902 0.4171710308775913 0.6765533128216945 1.0 0.938653317522555 2 Q14160 1 +Negative regulation of protein acetylation 0.358278829296223 0.4170063845581792 0.676673737779957 1.0 0.938653317522555 11 Q96EB6,Q01105 2 +Innate immune response 0.242897899120885 0.41614048207017 0.6773072087732097 1.0 0.9389390276891814 131 O60506,Q8IXJ6,Q9Y5A9,P12956,P04439,Q96JM3,Q86UT6,P07437,Q9UKG1,Q07021,Q9Y3Z3,Q96PK6,P23246,P08670,Q01804,P10321,O43823,P43243,Q14166,Q6ZWJ1,P46108,P14174,Q8WXF1,Q9NZ08 24 +Regulation of phosphatidylinositol dephosphorylation 0.5879136690647447 0.4153670174711854 0.6778732477492913 1.0 0.9393284604458634 2 Q9NYA4 1 +Response to acid chemical 0.3084074935248485 0.4148529619276702 0.6782495459091131 1.0 0.9396522830099132 24 O95831,Q9UQB8 2 +Telomeric d loop disassembly 0.5944512005771792 0.4105211513901375 0.6814236908556806 1.0 0.941335346990116 3 Q14191 1 +Telomeric loop disassembly 0.5944512005771792 0.4105211513901375 0.6814236908556806 1.0 0.941335346990116 3 Q14191 1 +Vesicle fusion to plasma membrane 0.4892214788170523 0.4101993101361934 0.6816597469130572 1.0 0.941335346990116 4 O95721 1 +L aspartate transmembrane transport 0.5941344626329905 0.4095718650330057 0.6821200392112203 1.0 0.941335346990116 3 Q9UJS0 1 +Lipid droplet organization 0.3851552222626253 0.4091834652998171 0.6824050276618159 1.0 0.9414503197788328 8 Q9Y679,Q8N0X7,Q14534 3 +Neural precursor cell proliferation 0.2980383343055105 0.4073616157068485 0.6837424144386424 1.0 0.9419148586109584 30 P55209,Q8NEM2,Q8IXJ6,Q15154 4 +T cell proliferation 0.3048612302726534 0.4058557410012435 0.6848485994722595 1.0 0.9429557065873588 26 P30825,P49366,Q9HCL2,P04439,Q96IZ0 5 +Positive regulation of interferon alpha production 0.4057636887607986 0.4029878727922627 0.6869571459377921 1.0 0.9439227248215366 7 O00571,P10809,O15111,Q7Z434,Q08211,Q9H2U1 6 +Interferon alpha production 0.4057636887607986 0.4029878727922627 0.6869571459377921 1.0 0.9439227248215366 7 O00571,P10809,O15111,Q7Z434,Q08211,Q9H2U1 6 +Positive regulation of double strand break repair via homologous recombination 0.3322121975268719 0.4029220030846132 0.6870056041087116 1.0 0.9439227248215366 17 Q7Z4V5,P09874,O95619,P35637 4 +Organ growth 0.3013701289404332 0.4028449599360053 0.6870622838433889 1.0 0.9439227248215366 28 O75844,Q9UGN5,Q9Y5Y0 3 +Dna integrity checkpoint signaling 0.2746204658600161 0.4010747952999723 0.6883650570435433 1.0 0.9449989617161688 46 Q6NUQ1,Q9Y619,P16104,Q96JB5,Q8N163,Q96RU2,P38398,Q9BXW9,P42575,Q6Y7W6,O75663,Q9HAW4 12 +Late endosome to lysosome transport 0.3761911025219354 0.4003761559535816 0.6888794836163394 1.0 0.9454336424803292 9 Q9HD42 1 +Regulation of epithelial cell migration 0.2726827713680532 0.3992824907689363 0.6896850670286976 1.0 0.946145098199477 47 P06576,Q8WTV0,P09601,P31749,P42785 5 +Negative regulation of protein dephosphorylation 0.354676351540062 0.3987301543012158 0.6900920466108609 1.0 0.9465063478599004 11 O75663,Q13464,Q15257,P62942 4 +Synaptic vesicle priming 0.4513667799629359 0.3983960354974555 0.6903382797981483 1.0 0.9466470188532776 5 O95721 1 +Regulation of mitochondrial membrane potential 0.3068347079763434 0.3972640560746132 0.691172750230288 1.0 0.9475941013873008 23 P31751,P09874,P30536,P31749,Q9BSK2 5 +Mitotic dna integrity checkpoint signaling 0.2987555145301552 0.3967081891652418 0.6915826606058841 1.0 0.9476523600770688 29 Q6NUQ1,Q9Y619,Q96JB5,P38398,Q9BXW9,P42575,Q6Y7W6,Q9HAW4 8 +Positive regulation of protein tyrosine kinase activity 0.42292903519054 0.3964263404426656 0.6917905375581577 1.0 0.9476523600770688 6 Q13432 1 +Cytoskeleton dependent cytokinesis 0.2722370823347397 0.3960404708585837 0.6920751725512799 1.0 0.9478452113781716 48 P16949,O95630,P25054,Q9Y2S7,Q9H444,O95235,O75935,Q6DKK2,Q9HD42,Q13432,P37198,Q12768 12 +Histone h3 acetylation 0.327622418519685 0.3934768103221138 0.6939673483028057 1.0 0.9496989628508816 18 Q03164,P38398,O60318,Q96EB6,Q92830 5 +Regulation of peptidyl serine phosphorylation 0.3031832064610208 0.3932303290780693 0.6941493709348681 1.0 0.9496989628508816 26 O95429,Q9H7B4,O00165,Q9NYB0,P14174,P31749,P05067 7 +Positive regulation of atp metabolic process 0.4219985215686826 0.3926888732687808 0.6945492897115115 1.0 0.9498746638833832 6 P05067 1 +Mrna cleavage involved in mrna processing 0.3667911962874187 0.3902675405565621 0.6963387229503653 1.0 0.9514907830760522 10 Q8N684,Q6UN15 2 +Mesenchyme development 0.2842556373132234 0.389794821228435 0.6966882735415294 1.0 0.9514907830760522 37 Q99729,Q53EL6,Q9UBV8,Q9UK61,O94788 5 +Vesicle targeting to from or within golgi 0.3362429572306863 0.389661009141563 0.6967872321040154 1.0 0.9514907830760522 14 Q15363,Q8N6H7,O15027,Q9UBV8 4 +Positive regulation of dna repair 0.2885441086396575 0.3889151082621695 0.6973389455287027 1.0 0.9514907830760522 33 P09874,P16104,Q96B01,P35637,Q7Z4V5,Q96EB6,O95619 7 +Protein autoubiquitination 0.3344063607685106 0.388785812405648 0.6974345968535052 1.0 0.9514907830760522 15 P22681,Q5W0B1,Q9NS91,Q6UWE0 4 +Inflammatory cell apoptotic process 0.448164003158607 0.386543569036655 0.6990941417098475 1.0 0.9514907830760522 5 O75844 1 +Blood vessel morphogenesis 0.2587148682940275 0.3857258598460058 0.6996997088105623 1.0 0.9514907830760522 86 Q9UII2,Q96AY3,Q04721,P06576,Q9H6E4,Q9P266,P38398,Q96PU8,Q05682,Q4VCS5,Q96JM3,P09601,Q9H2J4,Q96EB6,P31749,P42785,Q9NZ08,P05771 18 +Demethylation 0.3262872685377673 0.3853599125710839 0.6999707785826947 1.0 0.9514907830760522 18 Q01804,Q9UPP1 2 +Antigen processing and presentation of endogenous antigen 0.4195346410521887 0.3828425523718656 0.7018365085060636 1.0 0.9530916641686836 6 Q9NZ08,P10321 2 +Antigen processing and presentation of endogenous peptide antigen 0.4195346410521887 0.3828425523718656 0.7018365085060636 1.0 0.9530916641686836 6 Q9NZ08,P10321 2 +Regulation of fc receptor mediated stimulatory signaling pathway 0.4470058303401725 0.3822861487066415 0.7022491276272047 1.0 0.9534554918474452 5 Q9UJ41,Q9UKG1 2 +Regulation of intrinsic apoptotic signaling pathway 0.2686288846272491 0.3814802791385018 0.7028469018524992 1.0 0.954070506037519 54 P09874,O75489,P23246,Q8N163,P45880,Q9P0J0,Q9Y3D6,P14174,P61978,Q96EB6,P31749,Q9NYF8,Q9UL15 13 +Mrna 3 end processing by stem loop binding and cleavage 0.5766906474820108 0.3808829949769794 0.7032900711671031 1.0 0.9542788877512444 2 Q9UKF6 1 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.2901593810622441 0.3805803139100508 0.7035146911511478 1.0 0.9543871319734224 32 O43765,P31749,Q8IXJ6 3 +Activation induced cell death of t cells 0.418706607928634 0.3795500303708798 0.704279459645349 1.0 0.9550313561644792 6 Q99576,Q9HCL2,P31749 3 +Bone remodeling 0.3713396053096398 0.3779397858871952 0.7054753257812825 1.0 0.956259395509745 9 Q92791 1 +Response to type i interferon 0.3302697933344509 0.3766267841838772 0.7064509801748367 1.0 0.9565118440503544 16 Q14166,P18031,Q9Y5A9,Q7Z739,Q7Z434,Q9Y3Z3 6 +Apoptotic mitochondrial changes 0.2838617324169675 0.3759607193590885 0.706946098679857 1.0 0.95687507070698 35 Q9UII2,P02545,Q8N163,P45880,O14737,Q9Y3D6,P31749 7 +Positive regulation of lymphocyte mediated immunity 0.3273471917594622 0.3741751215117478 0.7082740320123571 1.0 0.9569194062468588 17 P43246,O96028,Q9NUQ9,Q12888,P04439,Q5RKV6,Q5UIP0 7 +Regulation of response to reactive oxygen species 0.370428982406612 0.3737687348195168 0.708576382315742 1.0 0.9569194062468588 9 Q96IZ0,P00374 2 +Negative regulation of dna repair 0.3354962696515162 0.3734089681886696 0.708844085782695 1.0 0.9570847707422496 12 Q9UBB9 1 +Neuron intrinsic apoptotic signaling pathway in response to oxidative stress 0.4780645428779049 0.3724367567794583 0.7095676911440452 1.0 0.9578473885336692 4 P09874 1 +Dephosphorylation of rna polymerase ii c terminal domain 0.5738129496402841 0.3722595081191542 0.709699643469627 1.0 0.9578473885336692 2 Q9NQG5 1 +Negative regulation of telomere maintenance via telomerase 0.3695509505518597 0.3697593036207691 0.7115618404464152 1.0 0.9589856753326712 9 Q96BK5,Q9H0A0,P09651,Q9NVN8 4 +Regulation of protein targeting 0.2888328270884357 0.3694774673250517 0.7117718653599989 1.0 0.9590725605024608 32 P55786,P31751,Q9UII2,O95429,O00165,Q96EP0,O14737,Q9Y3D6,O43464,Q9NQG6 10 +Cell motility involved in cerebral cortex radial glia guided migration 0.572374100719421 0.3679821517615564 0.7128865427140396 1.0 0.9597811196685054 2 Q8WXH0 1 +Positive regulation of immune response 0.2572957391885041 0.3675416183244707 0.713215053801104 1.0 0.9597811196685054 85 P46379,P12956,P04439,Q96EB6,O60828,Q9NUQ9,Q9UKG1,Q07021,P00813,Q96PK6,P23246,Q9UJ41,P43243,Q15233,Q96IZ0,O96028,Q8WXF1,Q07666,Q5RKV6,P05771 20 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.3690340015727794 0.3674044284605979 0.7133173687990091 1.0 0.9597811196685054 9 Q8N183 1 +Insulin secretion involved in cellular response to glucose stimulus 0.3690340015727794 0.3674044284605979 0.7133173687990091 1.0 0.9597811196685054 9 Q8N183 1 +Sulfur amino acid biosynthetic process 0.4427694534110806 0.3668458771598853 0.7137339846872335 1.0 0.9599496274962608 5 Q13126 1 +Methionine biosynthetic process 0.4427694534110806 0.3668458771598853 0.7137339846872335 1.0 0.9599496274962608 5 Q13126 1 +Response to mitochondrial depolarisation 0.375621948971358 0.366509442232722 0.7139849681719965 1.0 0.960091215364344 8 Q9UII2,Q13501 2 +Positive regulation of cell cell adhesion 0.2826398318380063 0.3651752977199963 0.7149805564675689 1.0 0.961037716557489 35 P30825,P49366,P31749,P00813,Q92845 5 +Proton transmembrane transport 0.2741412417221646 0.3645548698498599 0.7154437082026306 1.0 0.9614641226488136 44 Q13423,O75964,O00400,P06576,Q96ES6,P00846 6 +Negative regulation of muscle cell differentiation 0.3473097231911041 0.3620508940364033 0.717313998620732 1.0 0.9633778047304796 11 Q53EL6 1 +Positive regulation of leukocyte apoptotic process 0.3958430093541906 0.3615439038061582 0.7176928908059097 1.0 0.9633778047304796 7 Q96EB6,P07948 2 +Cardiac chamber morphogenesis 0.3469351105087783 0.360211687447214 0.7186888352339595 1.0 0.9633778047304796 11 O96028 1 +Oxidative rna demethylation 0.5694964028776943 0.359497061783475 0.7192232754648502 1.0 0.9633778047304796 2 Q9C0B1 1 +Oxidative demethylation 0.5694964028776943 0.359497061783475 0.7192232754648502 1.0 0.9633778047304796 2 Q9C0B1 1 +Negative regulation of binding 0.2761898795373482 0.358815503852619 0.719733113585683 1.0 0.9633778047304796 42 O75381,P48681,Q9UBB9,P40855,Q08379,P09601,P31749,O14981 8 +Positive regulation of defense response 0.2735418907467637 0.3586516423806933 0.7198557084515644 1.0 0.9633778047304796 44 P23246,Q13546,Q8WXF1,Q53EL6,P05067,P12956,P43243,Q96PK6,P33527,Q15233,Q6UWE0 11 +Regulation of heart rate 0.3317561864087515 0.3586041866633516 0.7198912143439875 1.0 0.9633778047304796 13 P00813 1 +Negative regulation of extrinsic apoptotic signaling pathway 0.2984742013685936 0.3582265765105407 0.7201737600054297 1.0 0.9633778047304796 26 P02545,Q13546,P38398,P61289,Q8IWB1,P09601,P31749 7 +Regulation of nuclear division 0.2703908665973006 0.3578848727681433 0.7204294717477486 1.0 0.9633778047304796 46 Q13123,Q96EA4,P37198,Q8IXJ6 4 +Metal ion homeostasis 0.2567662448086446 0.3569678832365993 0.7211158493144931 1.0 0.9633778047304796 88 Q8NEW0,P30519,P0DP25,Q8IWX8,Q15043,P98194,Q9Y3D6,Q9HD20,Q9Y5Y0,P09601,Q8IYU8,P05067,P05771 13 +Protein dna complex disassembly 0.3286592829721503 0.3568180186900646 0.721228046086237 1.0 0.9633778047304796 15 Q01105 1 +Cellular response to x ray 0.3939029433442294 0.3535942945437286 0.7236429507764046 1.0 0.9640734292468448 7 P12956 1 +Endocytosis 0.2409897281275484 0.3529971823248834 0.7240905529184045 1.0 0.9640734292468448 129 Q99816,Q99523,Q13464,Q14C86,O60749,Q8WTV0,Q2M2I8,Q08380,P41440,Q9UKG1,Q14677,P22681,O15118,Q8N6T3,Q9Y5X1,P46934,Q6UWE0,Q96ED9,Q06787,O15260,O14976,Q14108,Q9NX40,Q9UJ41,Q96D71,Q13596,Q9NVZ3,Q13432,P18031,Q9Y2T2,P0DP25,P11717,Q96T51,Q96PU5,P05067,P50897,P61978,P51790 38 +Positive regulation of proteolysis 0.2553704289653247 0.3527682669045451 0.7242621755610688 1.0 0.9640734292468448 101 O75150,O43847,P46379,Q8IXJ6,Q9P0J0,O95831,Q96EB6,Q9BXK5,Q9UL46,P61289,P31749,Q9NR28,Q9Y3D6,Q9UII2,O43765,Q96JB5,Q8NEZ5,O14737,P05067 19 +Negative regulation of supramolecular fiber organization 0.267297468150541 0.352009334807655 0.7248312618099142 1.0 0.9644412730342335 51 P16949,P25054,Q9NYL9,Q9Y3E1,P35611,O15212,P28289,Q9ULW0 8 +Chromosome organization involved in meiotic cell cycle 0.3204737865278115 0.3504927632162226 0.7259689202714579 1.0 0.9652981358520772 18 Q92791,Q9BTX1,Q9BXW9 3 +Endoplasmic reticulum calcium ion homeostasis 0.3448236887461678 0.3498943448379304 0.726417991274054 1.0 0.9652981358520772 11 P05067 1 +Sarcoplasmic reticulum calcium ion transport 0.3716936240503697 0.3493225773886922 0.7268471504753993 1.0 0.9652981358520772 8 O75844 1 +Stem cell differentiation 0.2710961968793571 0.3490557778507598 0.7270474351416889 1.0 0.9652981358520772 45 Q96DH6,Q9NX40,Q08J23,Q9Y5A9,Q9UBV8,O00231,O94788 7 +Myeloid cell development 0.3252861613520371 0.3484500081520932 0.727502251724224 1.0 0.9652981358520772 16 P05067,Q9Y5Y0 2 +Positive regulation of histone methylation 0.3044820514590229 0.3463985001120361 0.7290432521597823 1.0 0.9657551243427434 22 Q5VTR2,P18615,P02545,Q13573,Q9GZS3,Q03164,P38398,O43159,Q8N7H5,Q96EB6,Q5UIP0 11 +Response to tumor necrosis factor 0.2777685603953773 0.3447077046478762 0.7303141253000038 1.0 0.967049793328321 39 Q13546,O95429,Q8TCT8,Q96JM3,Q96EB6,P31749,Q92830,P78318 8 +Cell cycle checkpoint signaling 0.2532910327803793 0.340943680560268 0.7331459804299043 1.0 0.9691041657059212 66 P43246,P16104,Q8N163,P38398,Q13123,Q96FV9,Q9NZJ0,P25054,Q9Y619,Q08J23,Q9BXW9,P33981,P12270,Q6NUQ1,Q96EA4,Q6Y7W6,Q96JB5,Q96RU2,P42575,O75663,Q9HAW4,O60566,P49454 23 +Anterior posterior pattern specification 0.2980554723909017 0.3405486631888838 0.7334433823252051 1.0 0.9691041657059212 24 Q15363,O75787,Q9UK61,Q92830,O94788 5 +Hematopoietic stem cell proliferation 0.4085807871748574 0.3399871264916951 0.7338662226577204 1.0 0.9691041657059212 6 Q9Y5A9 1 +Rna polymerase i preinitiation complex assembly 0.3904899135446603 0.3397383292337573 0.7340535942271798 1.0 0.9691041657059212 7 Q9GZS1,P51532,Q12824,Q9NWS0,O15160,Q9UIF9 6 +Transcription initiation from rna polymerase i promoter 0.3904899135446603 0.3397383292337573 0.7340535942271798 1.0 0.9691041657059212 7 Q9GZS1,P51532,Q12824,Q9NWS0,O15160,Q9UIF9 6 +Aspartate family amino acid metabolic process 0.2983867914828566 0.3379854598234651 0.7353741450643392 1.0 0.9693643675442308 23 Q9BQT8,Q13126,Q9BV57,Q9UJS0 4 +Negative regulation of cholesterol metabolic process 0.5620143884892048 0.3378788111353143 0.7354545157679775 1.0 0.9693643675442308 2 O94905 1 +Negative regulation of alcohol biosynthetic process 0.5620143884892048 0.3378788111353143 0.7354545157679775 1.0 0.9693643675442308 2 O94905 1 +Regulation of cell cell adhesion 0.2626461283952904 0.337240532634102 0.7359355844628284 1.0 0.9693643675442308 57 Q9Y5A9,P30825,P49366,P31749,P00813,Q92845,Q96IZ0 7 +Regulation of deoxyribonuclease activity 0.3688417783867885 0.3369991118380301 0.7361175696347235 1.0 0.9693643675442308 8 Q96EB6,P31749 2 +Regulation of chromatin assembly 0.3231813972211907 0.3367192821999383 0.7363285262648165 1.0 0.9693643675442308 16 Q9UPP1 1 +Regulation of production of small rna involved in gene silencing by rna 0.3894415113731865 0.3355158558702228 0.7372359859360207 1.0 0.9698351317217516 7 O75844 1 +Establishment of protein localization to endoplasmic reticulum 0.2979917728087795 0.3352643060002505 0.7374257168169345 1.0 0.9698351317217516 23 O43765,P46379,Q9H444,O43681,Q15629 5 +Regulation of double strand break repair 0.2787253529963723 0.3349463452163354 0.7376655608639784 1.0 0.9698351317217516 36 Q9NRR5,O96028,P09874,Q96B01,P35637,Q7Z4V5,Q9UBB9,O95619 8 +Protein localization to lysosome 0.3228211114435267 0.33472166660877 0.7378350557422984 1.0 0.9698351317217516 16 Q9Y2T2,Q99523,Q14108,Q8IWJ2,O00189,O14964,P46934 7 +Oogenesis 0.3203793805815871 0.3339306012439906 0.7384319274780133 1.0 0.969890436790007 17 Q8IXJ6 1 +Positive regulation of protein localization to membrane 0.284484756020836 0.3335051981705496 0.7387529662657588 1.0 0.969890436790007 32 P31751,Q9Y3D6,Q13501,P98194,P31749,O00264 6 +Leukocyte mediated immunity 0.2647458627394227 0.3334553893374486 0.7387905584601893 1.0 0.969890436790007 53 P43246,O96028,P07437,Q9NUQ9,Q9UQ84,Q9UJ41,Q12888,Q7Z434,P22681,P04439,Q96FV9,Q07021,P68371,P46108,P09601,Q5RKV6,P07948,Q5UIP0 18 +Positive regulation of ubiquitin dependent protein catabolic process 0.278965090657165 0.3330675376056194 0.7390833029477348 1.0 0.969890436790007 35 O43765,Q8IXJ6,Q96JB5,Q8NEZ5,P31749 5 +Polyadenylation dependent snorna 3 end processing 0.3885336551521964 0.3318724624054949 0.7399855648501239 1.0 0.970494603263827 7 Q5RKV6,O95453,Q13868 3 +Ire1 mediated unfolded protein response 0.388090953288507 0.3301002358410395 0.741324225034321 1.0 0.971670045504504 7 Q92905,Q96HY6 2 +Smooth muscle cell proliferation 0.3102548459099774 0.3294327778384721 0.7418285960437538 1.0 0.9717512165670564 20 P12956,P31749,Q5VZE5 3 +Endocardium development 0.5588489208633056 0.3289294216561418 0.7422090353199984 1.0 0.9720563175757244 2 Q06330 1 +Cardiac ventricle development 0.3230859129205857 0.3265090244530205 0.7440392625803294 1.0 0.9730993849030944 15 O96028,O75844 2 +Protein localization to microtubule end 0.5576978417266151 0.3257046342735244 0.744647837630104 1.0 0.9737020444819916 2 Q15691 1 +Dna methylation or demethylation 0.2925730025067957 0.3243117388066783 0.7457020332859563 1.0 0.9741139368202152 27 P09874,Q01804,Q03164,Q5T5X7,O95983,O75844 6 +Regulation of response to wounding 0.305236318277204 0.3225985443576435 0.7469992962726897 1.0 0.974842218883096 21 Q96G23,Q16625 2 +Aortic valve morphogenesis 0.4624244169306097 0.3217992874364987 0.7476047541539139 1.0 0.974977077261081 4 O75116,Q13464,O94813 3 +Striated muscle cell development 0.3388797521669593 0.321310400879179 0.7479751752118242 1.0 0.974977077261081 11 Q9NYL9 1 +Angiotensin activated signaling pathway 0.5627518710420121 0.3200672652246235 0.7489173399552218 1.0 0.9751197416276782 3 O75116,Q13464 2 +Acetyl coa biosynthetic process from pyruvate 0.364691262211673 0.3193032259615654 0.7494965866612471 1.0 0.9753966046831832 8 Q15118,Q15120 2 +Regulation of protein secretion 0.2646006548097306 0.3184116383446557 0.7501727112076948 1.0 0.9755460967994172 49 Q16850,O00233,Q6ZWJ1,P53367,Q8N183,P53985,Q6WKZ4,P00367 8 +Regulation of peptidase activity 0.2539708519243576 0.317915158611958 0.7505492937753373 1.0 0.9755460967994172 89 O43847,Q9P0J0,O95831,Q96EB6,Q9BXK5,Q9HB09,Q9UL46,P61289,P31749,Q96HY6,P51812,Q9NR28,Q15418,Q15392,Q9Y3D6,Q92530,O14737,P42575,P05067 19 +Negative regulation of mitochondrion organization 0.3213832591914972 0.3173932690549339 0.7509452139161423 1.0 0.9755460967994172 15 P30536 1 +Positive regulation of catabolic process 0.239657145261947 0.3173092613935653 0.7510089506289503 1.0 0.9755460967994172 164 O60506,P21796,O75150,O43847,P46379,Q8IXJ6,Q9Y5A9,Q9P0J0,Q8TBX8,Q13148,Q96EB6,Q969T7,P25054,P27544,P31749,Q96HY6,P46934,Q6UWE0,P31751,P67809,Q6Y7W6,P09601,Q86VM9,Q92945,Q9UII2,O43765,Q96JB5,Q8NEZ5,Q96PU5,P05067 30 +Peptidyl arginine methylation 0.428671920245777 0.3170438685461339 0.7512103156587031 1.0 0.9755460967994172 5 Q6P2P2 1 +Peptidyl arginine n methylation 0.428671920245777 0.3170438685461339 0.7512103156587031 1.0 0.9755460967994172 5 Q6P2P2 1 +Telomere organization 0.248447447498997 0.3167029798961803 0.7514689874760507 1.0 0.9755460967994172 68 P09874,Q9UPR3,Q9UQ84,Q8IXJ6,Q96HR8,P41440,Q96SB8,O95453,P12956,O94761,Q9UBB9,P49750,Q9NYB0,P22626,Q14191,Q96BK5 16 +Molting cycle 0.3221642671518411 0.3142963321175053 0.7532959837347053 1.0 0.9764838160196682 14 O75844 1 +Regulation of immune effector process 0.264298520720831 0.3132332296490817 0.754103474166004 1.0 0.976575699550398 47 P43246,O96028,Q9NUQ9,Q9UJ41,Q9UKG1,Q12888,Q7Z434,P04439,Q96FV9,Q07021,P46108,P14174,P09601,Q96EB6,Q5RKV6,P07948,Q5UIP0 17 +Glycerophospholipid biosynthetic process 0.2640543462813532 0.3128070753846153 0.7544272395844644 1.0 0.976575699550398 49 Q6UWP7,Q9BTU6,Q9HBU6,Q9NPH0,O15228,P42356,Q8TBX8,P35790,Q10713 9 +Negative regulation of anoikis 0.4595450619061314 0.3127894671341794 0.7544406181633212 1.0 0.976575699550398 4 Q07820,P05556,Q9Y3E5 3 +Regulation of cyclic nucleotide phosphodiesterase activity 0.4594686334882565 0.3125516908218255 0.7546212855263945 1.0 0.976575699550398 4 P0DP25 1 +Regulation of cell differentiation 0.2572374837515295 0.3124882981138168 0.7546694548853661 1.0 0.976575699550398 231 Q8IXJ6,Q99523,Q9Y5A9,Q15154,P12956,Q9BYT8,Q8WUJ1,Q92896,P25054,Q08J23,O00165,P30536,Q53EL6,Q9BXW9,Q07021,Q9UGN5,Q96A49,P00813,P31749,Q8N4Q0,P55209,P67809,Q9UQB8,P51812,Q04721,Q9NX40,Q15418,P35611,Q8N7H5,Q15051,Q92830,P09874,Q13546,Q8NEZ5,P46108,Q96G23,P05067 37 +Negative regulation of cell cycle process 0.253346147500754 0.3101272391514252 0.756464198907036 1.0 0.9767475223590948 88 P43246,Q96K76,P16104,Q8N163,Q7Z5K2,P38398,Q13123,P49454,Q9NZJ0,P25054,Q9Y619,Q08J23,Q9BXW9,P33981,Q96PK6,Q6NUQ1,Q96EA4,Q96DY7,Q6Y7W6,Q92830,Q96JB5,Q9NPI1,Q96RU2,P42575,O75663,Q9HAW4,O60566,Q96BK5 28 +Negative regulation of ion transmembrane transport 0.3132029608762198 0.3080490327385338 0.758045022491028 1.0 0.977639196162338 18 P21796,P46934 2 +Rap protein signal transduction 0.4250850131331781 0.3047820324707662 0.7605321668776017 1.0 0.979813136607918 5 P22681,Q15058 2 +Multivesicular body organization 0.3168103595060395 0.3018598073726918 0.7627589363766702 1.0 0.98064753790944 16 Q99816,Q9H444,O14964,Q9HD42,Q9Y3E7,Q9H9H4 6 +Mast cell activation 0.3598666802703504 0.2991037845974413 0.7648608587073702 1.0 0.9825829982497296 8 P09601,P22681,Q9UJ41 3 +Positive regulation of developmental process 0.2501267684395831 0.2985308014793382 0.7652980710563757 1.0 0.9828570942155754 204 Q8IXJ6,P12956,Q96JM3,Q8WUJ1,P41440,O00165,P30536,Q9P266,Q07021,Q9UGN5,P00813,P31749,P55209,Q9UQB8,P51812,Q15418,P09601,Q92830,Q96IZ0,O96028,P09874,P46108,Q5RKV6,Q9NZ08,P05771 25 +Pyrimidine nucleoside triphosphate metabolic process 0.3198201564731764 0.297301777429368 0.7662361247690521 1.0 0.9828570942155754 13 Q9H773 1 +Positive regulation of cysteine type endopeptidase activity 0.2750911928820793 0.2972606111418134 0.7662675509159829 1.0 0.9828570942155754 34 Q9NR28,Q9BXK5,O14737,Q9P0J0,Q9Y3D6,O95831,Q96EB6 7 +Insulin secretion 0.2858436875487581 0.2967011468588819 0.7666946813798092 1.0 0.9832135569504794 29 Q8N183,O00233,P00367,P53985 4 +Zinc ion homeostasis 0.4225819443382974 0.2963285498350794 0.7669791848881016 1.0 0.9833041777311182 5 Q8NEW0 1 +Nucleotide transmembrane transport 0.3459697285080168 0.2944241338036342 0.7684338276327942 1.0 0.9841388412382795 10 P41440 1 +Negative regulation of peptidase activity 0.2703652371798666 0.293970440549039 0.7687804909136458 1.0 0.9841388412382795 41 P05067,Q15418,P31749,P51812 4 +Rna catabolic process 0.232082981125026 0.2938745283107264 0.7688537825882493 1.0 0.9841388412382795 145 P51116,O60506,Q9Y2W1,Q9Y5A9,Q9H814,Q9P2K5,Q13148,P98175,Q969T7,Q14011,Q99729,Q13151,Q08J23,Q9BQG2,Q9BQ61,P31749,P67809,P08670,P35637,P52272,Q6Y7W6,Q92804,Q6PJT7,Q86VM9,Q92945,P51114,O75312,O95453,P62312,Q5RKV6 30 +Sphingosine biosynthetic process 0.4528784702318701 0.2923219222715509 0.77004049891702 1.0 0.9850120068655106 4 O15269 1 +Regulation of mononuclear cell migration 0.2955607705629088 0.2878294685878323 0.7734772788004309 1.0 0.9872469096705128 22 P46108,P31749,P05067 3 +Positive regulation of chromosome separation 0.3316957965991661 0.2877222437344981 0.7735593616614915 1.0 0.9872469096705128 11 Q14674,Q14980,Q9UJX5,Q9UJX3,Q9UJX2,Q9UJX4 6 +Hindbrain development 0.2732388258666043 0.287400953322482 0.7738053313304447 1.0 0.9872469096705128 36 Q9BRK5,Q92830,P31939,O94788 4 +Intracellular transport of virus 0.4511236788242914 0.28702770277453 0.774091108537629 1.0 0.9872469096705128 4 P52292,P49790 2 +Cell cycle dna replication 0.2995458688570097 0.2867909360009113 0.7742724035751043 1.0 0.9872469096705128 21 P33991,O75312,Q14566,O95785,O75844 5 +T cell receptor signaling pathway 0.2902079106587422 0.2863758813514676 0.7745902453871674 1.0 0.9872469096705128 24 P00813,Q96IZ0 2 +Positive regulation of immunoglobulin production 0.3173589241672866 0.285071134179406 0.7755896444726793 1.0 0.9872469096705128 13 P43246,O96028,Q12888,Q9NQT5,Q5RKV6,Q5UIP0 6 +Regulation of gene expression epigenetic 0.2608764556453818 0.2848534382545689 0.7757564295701371 1.0 0.9872469096705128 51 Q9UPP1,Q5T5X7,Q8IXJ6 3 +Regulation of synapse structure or activity 0.2729297900064765 0.2847606615755368 0.7758275124432896 1.0 0.9872469096705128 36 Q9UQB8,P05067,P50897,P46934 4 +Establishment of protein localization to vacuole 0.3061911729504543 0.2845341397798523 0.7760010749393755 1.0 0.9872469096705128 19 Q99523,Q14108,P46934 3 +Response to peptide hormone 0.2514676471049488 0.283815058381759 0.7765521139396943 1.0 0.9872469096705128 94 P31751,O75150,Q9UQB8,P09874,P25054,Q6ZWJ1,Q99523,Q15043,Q9UKG1,P09960,P46108,Q9HCD5,Q8TBX8,Q96A49,Q96EB6,P31749,Q9BSK2,P05771 18 +Muscle adaptation 0.3060388824664787 0.2836502985600935 0.7766783868244445 1.0 0.9872469096705128 19 P09874,Q9UGN5 2 +Mitotic spindle midzone assembly 0.4496947660207547 0.2827459155893294 0.777371616206453 1.0 0.9872469096705128 4 O43663,Q9H0H5 2 +Positive regulation of nf kappab transcription factor activity 0.2854998048204145 0.2826604951024289 0.7774371020546602 1.0 0.9872469096705128 28 Q13546,P41440,P05067,Q9NYB0,Q86UE4,Q96HY6,P05771 7 +Regulation of histone modification 0.2461983657629407 0.2825548177476428 0.7775181195993788 1.0 0.9872469096705128 69 Q5VTR2,Q14166,O75150,P18615,P02545,O75844,Q9ULX6,P50750,P38398,Q03164,Q9NPI1,Q92830,O43823,Q8N7H5,Q96L73,Q96EB6,Q8WTS6,Q01105 18 +Meiosis i cell cycle process 0.2894649705876147 0.2813537308552728 0.778439102670496 1.0 0.9875809428833572 24 Q92791,Q9BXW9,Q9BTX1,P46379 4 +Response to lead ion 0.448636649308899 0.2795922864149589 0.7797903257284187 1.0 0.9877027308802832 4 P05067 1 +Ventricular septum development 0.3485088353035691 0.2775979407676796 0.7813210130679082 1.0 0.9877027308802832 9 O96028 1 +Aminoglycan biosynthetic process 0.3419632517741935 0.2769074401622597 0.7818511794848366 1.0 0.9877027308802832 10 P06865,Q8N6G5,Q96L58,Q8NCH0 4 +Immunoglobulin production 0.2846290343920676 0.2763172908820989 0.7823043765057536 1.0 0.9877027308802832 28 O96028,Q5RKV6,Q9UQ84 3 +Negative regulation of telomerase activity 0.4164577199352434 0.2760134102637278 0.7825377662819073 1.0 0.9877027308802832 5 P27544 1 +Negative regulation of apoptotic signaling pathway 0.2456092531292265 0.2752069826211492 0.7831572226748404 1.0 0.9877027308802832 69 O60313,Q8N163,P38398,Q9P0J0,Q96EB6,P02545,P61289,O43464,P31749,Q9UL15,Q9NY61,P45880,P09601,Q15233,Q86WB0,O75489,P18031,Q13546,P14174,Q8IWB1 20 +Positive regulation of nervous system process 0.4161866359447068 0.2751264842272607 0.7832190649697508 1.0 0.9877027308802832 5 Q9UPY3,P04062,O75746,O14795 4 +Protein localization to organelle 0.2699624671636457 0.2750950080202592 0.7832432467051622 1.0 0.9877027308802832 343 Q99595,O60830,P46379,Q7Z5K2,Q9NS69,Q9UK61,O95831,P55786,Q15070,P02545,O95429,P30536,Q9UKG1,Q96HY6,P46934,Q9UHB9,Q6UWE0,P24390,O14976,Q9BVL2,Q7Z4Q2,Q3ZCQ8,Q96EA4,Q96DY7,O43615,P09874,O75312,Q13561,P57740,Q9H1Z9,Q15629,Q14191,Q9UPN4,P35658,Q9NYB0,P51858,O14925,O00165,O43681,P31749,P37198,Q9Y679,Q99797,Q8NG31,O75381,Q14978,A0AVF1,P52292,Q8N4V1,Q8NEY8,Q15006,Q9Y2T2,Q9UNZ2,P0DP25,P56589,Q96EP0,Q9Y5K8,P40855,Q9NVN8,Q9NVM9,Q9UH99,P52948,Q99816,Q8TD16,O00189,Q13123,Q96JM3,Q10713,P49790,Q9H444,P49792,P33981,O43464,Q96C92,O15027,Q9P275,Q92973,Q14108,Q9Y3D6,Q8N4H5,Q8N1F7,O43765,Q99523,Q5JRX3,Q15154,Q9P0J0,Q13501,Q13148,Q9H9H4,P25054,P67809,Q99567,Q8N7H5,Q9UII2,Q96JB5,Q76FK4,O14737,Q9Y512,Q96BK5 99 +Protein localization to nucleolus 0.3156805086437951 0.2743118373002267 0.7838449884415821 1.0 0.9877027308802832 12 Q76FK4,Q96BK5 2 +Positive regulation of bmp signaling pathway 0.3537057151194905 0.2739153265667045 0.7841496929934646 1.0 0.9877027308802832 8 Q04721 1 +Cellular response to extracellular stimulus 0.2602962928420963 0.2736573879691679 0.7843479275032341 1.0 0.9877027308802832 48 Q9P289,Q13573,Q8NEZ5,P09651,P22681,P21964,P11166,O95831,Q96EB6,Q9H773,Q14191,P07948,P09601 13 +Interstrand cross link repair 0.3735025732814812 0.2733973328254189 0.7845478028160429 1.0 0.9877027308802832 7 Q9H1E3,Q9BXW9 2 +Import into nucleus 0.2463683666099978 0.2727603770255622 0.7850374195289191 1.0 0.9877027308802832 67 P35658,Q13501,Q13148,P49790,P02545,Q9UKG1,P49792,P09651,P31749,P37198,Q92973,Q15717,Q99567,Q9BVL2,Q7Z4Q2,Q14978,P52292,Q8N1F7,O75312,P57740,P52948 21 +Regionalization 0.27684996587227 0.272039274603995 0.7855918209309671 1.0 0.9877027308802832 32 Q15363,Q04721,P62995,O75787,Q9UK61,Q92830,O94788 7 +Positive regulation of monocyte chemotaxis 0.4454362222862029 0.2701429146431452 0.7870503078716027 1.0 0.9889198898919508 4 Q8NHP6,Q4KMQ2,P09429 3 +T cell homeostasis 0.3403557299468215 0.2699706281324329 0.7871828502150091 1.0 0.9889198898919508 10 Q99576,Q9HCL2,P31749 3 +Response to hydrogen peroxide 0.2820627168801349 0.2685245767976863 0.7882955597408301 1.0 0.9891946242316736 29 O95831,Q99720,Q96IZ0,P09601 4 +Response to dexamethasone 0.346317694336274 0.2684695677282053 0.7883378967396197 1.0 0.9891946242316736 9 Q9H7B4 1 +Positive regulation of leukocyte cell cell adhesion 0.2845702645934254 0.2665587744927778 0.7898089005803606 1.0 0.9897396055389872 27 P00813,P30825,P49366 3 +Cellular response to oxygen containing compound 0.2539267807678469 0.2660839350613757 0.790174567116392 1.0 0.990009549863074 227 Q8IXJ6,Q9H7B4,P04150,Q9P0J0,Q8WTV0,Q96JM3,Q8TBX8,Q96JN0,O95831,O94788,Q99729,P25054,P00374,Q99808,Q8N183,P30536,Q53EL6,P62995,Q96A49,P31749,P31751,Q9UQB8,P08670,Q15043,O43823,Q96IZ0,Q9BSK2,P09874,Q6ZWJ1,Q99720,P46108,P14174,P33527,P05067,P05771 35 +Regulation of smooth muscle cell differentiation 0.388404751786484 0.2653844812823098 0.7907132898386153 1.0 0.9903079009212388 6 Q53EL6 1 +Water homeostasis 0.3391524933744765 0.2648133754633218 0.7911532325110553 1.0 0.9906705908429008 10 P16949,Q16739 2 +Regulation of t cell mediated immune response to tumor cell 0.5338129496402839 0.2624857993566186 0.7929469321304488 1.0 0.9921624260933398 2 P10809 1 +Regulation of response to tumor cell 0.5338129496402839 0.2624857993566186 0.7929469321304488 1.0 0.9921624260933398 2 P10809 1 +Vasculogenesis 0.3502395384141576 0.2600558227540365 0.7948207140932744 1.0 0.9932472916992936 8 Q92990,O95470,Q96PU8,Q4VCS5,Q9Y4G8 5 +Head morphogenesis 0.3868792575135067 0.2599930025336274 0.7948691712142018 1.0 0.9932472916992936 6 Q9Y5Y0 1 +Gdp metabolic process 0.4414823146437537 0.2586567586213354 0.7959000859577532 1.0 0.9937816309220456 4 Q00013,O14936 2 +Negative regulation of cellular component organization 0.244967041947638 0.2569045135344971 0.7972524862017034 1.0 0.9946107425599794 193 Q8IXJ6,Q7Z5K2,P38398,O15212,Q13123,Q9NR77,Q9UBB9,Q9NYB0,Q9NQX7,P16949,P25054,P02545,Q9NUQ9,P30536,Q9H444,P28289,Q96PK6,P31749,Q15058,Q9ULW0,Q9UL15,Q6UWE0,Q9NRR5,Q9H0A0,P08670,O14976,Q9NYL9,Q9Y3E1,Q9UJ41,P35611,P45880,Q96EA4,Q9UHB6,Q96DY7,Q13432,Q86X55,Q92830,P09874,Q9UPP1,Q9UEY8,Q8N0X7,Q9NVN8,Q96G23,P05067,Q96BK5,O00264 46 +Positive regulation of calcium ion transport 0.3040540530949813 0.2566686701375709 0.7974345590697325 1.0 0.9946107425599794 18 P30536 1 +Regulation of peptidyl tyrosine phosphorylation 0.2700733299297529 0.2556373465583023 0.7982308779498601 1.0 0.9946107425599794 34 O00165,P14174,O95684,Q13432,P05067 5 +Negative regulation of chromosome organization 0.263877021704072 0.2543256720197356 0.7992439682776822 1.0 0.9946107425599794 43 P09874,P25054,Q9H0A0,Q7Z5K2,P07910,P09651,P33981,Q13123,Q96EA4,P49454,Q9NYB0,Q9NVN8,O60566,Q96BK5 14 +Negative regulation of homotypic cell cell adhesion 0.5303597122302119 0.2539498949833758 0.7995342673322978 1.0 0.9946107425599794 2 P35241 1 +Negative regulation of filopodium assembly 0.5303597122302119 0.2539498949833758 0.7995342673322978 1.0 0.9946107425599794 2 P47756 1 +Positive regulation of epithelial cell proliferation 0.2856675179186833 0.2529098733566974 0.8003378596225543 1.0 0.9946107425599794 23 Q04721,Q6ZWJ1,Q9P266,P09601,Q96EB6,P31749 6 +Nuclear transport 0.2306796034810163 0.2497439850885337 0.8027853405754135 1.0 0.9972566480380262 148 Q96GA3,Q9ULX6,P35658,P52948,O60318,P39687,Q96FV9,Q9H814,Q13501,Q13148,Q86V81,P22626,Q96MU7,Q9UPR3,P02545,P49790,Q08J23,Q9UKG1,P49792,P09651,Q96ST2,Q53F19,P31749,P37198,P46934,Q92973,Q15717,Q99567,Q9BVL2,Q6I9Y2,Q7Z4Q2,Q14978,Q7Z434,O15504,P52292,Q9BVS4,Q9BZI7,Q8N1F7,O75312,Q86U42,Q9H6Z4,Q9BWF3,Q8NEZ5,P57740,Q07666,P82979 46 +Regulation of dna methylation dependent heterochromatin assembly 0.3417054382913157 0.2495685695551045 0.8029210074126163 1.0 0.9972566480380262 9 Q8NEY8 1 +Glutathione metabolic process 0.2993130169213713 0.2453099878960233 0.8062164187618961 1.0 0.9979141076227585 19 P21266,Q9H7Z7 2 +Positive regulation of receptor mediated endocytosis 0.3094270140781279 0.2449551976401509 0.8064911217401121 1.0 0.9979141076227585 12 P50897,P61978 2 +Placenta development 0.2797602509042214 0.2413918826049304 0.8092514035112937 1.0 0.9999209385242332 28 Q15363,Q04721,Q9H6E4,P00813,P31749 5 +Pyrimidine nucleobase metabolic process 0.3082122478106829 0.2409550345794408 0.809589967018429 1.0 0.9999209385242332 13 Q02252 1 +Embryonic placenta morphogenesis 0.4054345296158772 0.2408199425529512 0.8096946725008312 1.0 0.9999209385242332 5 Q15363,O75190 2 +Late endosome to vacuole transport 0.3212082816195374 0.2407294985935225 0.8097647746070895 1.0 0.9999209385242332 11 Q9HD42 1 +Protein localization to vacuole 0.2880545853983898 0.2405411332188277 0.8099107794114087 1.0 0.9999209385242332 22 Q99523,Q14108,P46934 3 +Peptidyl tyrosine modification 0.2610820339459389 0.2396713541847001 0.8105850438048625 1.0 0.9999209385242332 44 O00165,P14174,P49761,O95684,Q13432,P05067 6 +Positive regulation of myeloid cell differentiation 0.3031284283401559 0.2396339835848334 0.8106140171490663 1.0 0.9999209385242332 17 O00165,Q04721 2 +Cardiac chamber development 0.2982165151420683 0.239192371504768 0.8109564176662434 1.0 0.9999209385242332 19 O96028,O75844,Q04721 3 +Regulation of dna repair 0.2552795620922459 0.2384930889911331 0.8114986749229036 1.0 0.9999209385242332 54 Q9NRR5,O96028,P09874,P16104,Q96B01,P50750,P38398,P35637,Q7Z4V5,Q9UBB9,Q96EB6,O95619 12 +Protein k11 linked ubiquitination 0.3328670924663447 0.2383732418384178 0.8115916192483834 1.0 0.9999209385242332 10 Q9UJX5,Q9UJX3,Q13042,Q9UJX2,Q9UJX4 5 +Cellular response to hormone stimulus 0.2275771936965805 0.23776870003884 0.8120604962861226 1.0 0.9999918770995022 141 Q9H7B4,P04150,Q8TBX8,O95831,Q96EB6,P25054,Q9UKG1,Q9H1E3,Q92841,O15118,Q9P253,Q96A49,P31749,P46934,P31751,Q9UQB8,O15173,Q15043,Q16739,O43823,P42785,Q9BSK2,P09874,Q6ZWJ1,P46108,Q8IZL8,Q9HCD5,P05771 28 +Negative regulation of actin filament depolymerization 0.3026259545906118 0.2370131851878086 0.8126465613616718 1.0 0.9999918770995022 17 P28289,P35611,Q9NYL9 3 +Positive regulation of autophagy of mitochondrion 0.3802223835783952 0.2369050834704615 0.8127304262005881 1.0 0.9999918770995022 6 P21796 1 +Positive regulation of hematopoietic progenitor cell differentiation 0.5231654676258953 0.2366751777714686 0.8129087931751369 1.0 0.9999918770995022 2 O43809 1 +Cardioblast differentiation 0.523165467625895 0.236675177771468 0.8129087931751373 1.0 0.9999918770995022 2 Q06330 1 +Negative regulation of striated muscle cell apoptotic process 0.5223021582733772 0.2346488568245923 0.814481285769181 1.0 1.0 2 O95817 1 +Mitotic g2 m transition checkpoint 0.2971527821025894 0.2332944345546218 0.8155327799731553 1.0 1.0 19 Q6NUQ1,Q9Y619,Q96JB5,P38398,Q9HAW4 5 +Regulation of ph 0.2867162800643301 0.2323171212995789 0.8162917153071179 1.0 1.0 22 Q15904,P06576,Q93050,O75503,Q8N511,O75787,P50897 7 +Regulation of cellular ph 0.2867162800643301 0.2323171212995789 0.8162917153071179 1.0 1.0 22 Q15904,P06576,Q93050,O75503,Q8N511,O75787,P50897 7 +Negative regulation of protein polymerization 0.2796044458103452 0.2319280384369971 0.8165939066887353 1.0 1.0 27 P16949,P45880,Q9NYL9,P28289 4 +Regulation of viral transcription 0.4023617511520771 0.2313369587055689 0.8170530363901547 1.0 1.0 5 P19474,Q96T23,Q4G0J3,Q08211 4 +Columnar cuboidal epithelial cell maturation 0.5194244604316511 0.2279672909665625 0.8196716690492782 1.0 1.0 2 Q86UL3 1 +Vascular endothelial cell proliferation 0.5259067357512806 0.2278691505165668 0.8197479661474083 1.0 1.0 3 P40763,P09429 2 +Positive regulation of vascular endothelial cell proliferation 0.5259067357512806 0.2278691505165668 0.8197479661474083 1.0 1.0 3 P40763,P09429 2 +Mrna catabolic process 0.2383528118984319 0.2270594813860293 0.8203774903482777 1.0 1.0 122 P51114,O60506,Q14011,Q99729,Q9Y2W1,P08670,Q13151,Q9Y5A9,P35637,P31749,Q9BQG2,Q6Y7W6,Q13148,Q92804,P98175,Q969T7,Q5RKV6,Q92945 18 +Regulation of chromatin assembly or disassembly 0.298566950894366 0.2270369326339002 0.8203950238411399 1.0 1.0 18 Q9UPP1 1 +Membrane depolarization during action potential 0.5188489208633051 0.2266444688707237 0.8207002107788417 1.0 1.0 2 Q04917 1 +Mitochondrial genome maintenance 0.3358434139493902 0.2261819935224364 0.8210598748347735 1.0 1.0 9 P09874 1 +Body morphogenesis 0.3358405608415925 0.2261707892203098 0.8210685888144058 1.0 1.0 9 Q9Y5Y0 1 +Negative regulation of tor signaling 0.3770174782086461 0.2260509916602385 0.8211617609682162 1.0 1.0 6 Q96EB6 1 +Long chain fatty acyl coa biosynthetic process 0.4000576036866372 0.2243226068757973 0.8225062866577708 1.0 1.0 5 P33121,Q53GQ0,Q9NZ01,O95573 4 +Cardiac left ventricle morphogenesis 0.5176978417266145 0.2240123612877207 0.8227476847284769 1.0 1.0 2 Q06330 1 +Formation of extrachromosomal circular dna 0.3761749827267889 0.223226566503202 0.8233591764765915 1.0 1.0 6 Q9UQ84 1 +Immune effector process 0.2453824224724555 0.2226173758831589 0.8238333117907062 1.0 1.0 80 O96028,P07437,Q04721,P00813,Q9UQ84,P22681,P04439,P46108,Q5RKV6,Q07021,P14174,P09601,Q96EB6,P05067 14 +Neuron projection organization 0.2780986775408558 0.2216233397556818 0.8246071117836 1.0 1.0 27 Q9UQB8 1 +Substantia nigra development 0.2948081735870012 0.2204249567239785 0.825540210692512 1.0 1.0 19 P00367,Q16352,Q8IXJ6,P0DP25 4 +Regulation of immune system process 0.2479329266864982 0.2200307391105404 0.8258472149341469 1.0 1.0 212 P46379,P28070,Q8TCT8,Q9Y5A9,P49366,P12956,P04439,Q86U70,Q86UT6,Q99576,Q96EY1,Q96EB6,O60828,P41440,O00165,Q9UKG1,Q9HCL2,Q9BXW9,Q07021,Q9Y3Z3,P00813,Q96PK6,P31749,Q04721,P51812,P23246,O96005,P30825,Q01804,Q8N7H5,P09601,P43243,Q00013,Q15233,Q92830,Q96IZ0,O96028,Q14166,Q13546,Q66K64,P46108,Q5RKV6,P14174,Q8WXF1,Q07666,P05067,Q9NZ08,P05771 48 +Protein localization to endoplasmic reticulum 0.2650384057122775 0.2188293367406943 0.8267829932574249 1.0 1.0 36 O43765,P46379,Q9H444,O43681,Q15629,Q96HY6,Q9UHB9 7 +T cell differentiation in thymus 0.3338927566022531 0.2185629324329392 0.8269905302816356 1.0 1.0 9 P00813,O96005 2 +Protein localization to cell cortex 0.3980414746543899 0.2182538052892864 0.8272313648347569 1.0 1.0 5 P11171,P15311,Q14980,O43491 4 +Receptor metabolic process 0.2639506454161724 0.2173239299313344 0.8279559093271651 1.0 1.0 38 P42892 1 +Spliceosomal tri snrnp complex assembly 0.3030342258655282 0.2160026154683735 0.8289857088420405 1.0 1.0 12 O75494,O95400 2 +Endoplasmic reticulum membrane organization 0.3331067991307644 0.2155165878217136 0.829364580700481 1.0 1.0 9 Q8NHH9,Q9P2W9 2 +Cell fate specification 0.3386349085632522 0.2153843300746361 0.8294676861085855 1.0 1.0 8 P25054 1 +Negative regulation of dephosphorylation 0.3020505338277773 0.2149358810767645 0.8298173095388561 1.0 1.0 14 O75663,Q15257 2 +Heart valve development 0.3267151254477916 0.2133390412014776 0.8310625239316161 1.0 1.0 10 Q04721 1 +Regulation of protein dephosphorylation 0.275680054713657 0.2128677630571869 0.8314301074552901 1.0 1.0 28 O75663,Q15257,Q86XL3,P0DP25 4 +Regulation of leukocyte chemotaxis 0.2957425848123914 0.2121539992877115 0.8319868930528846 1.0 1.0 18 Q00013,Q07021 2 +Response to calcium ion 0.2782712961943028 0.2115408329105225 0.8324652729986222 1.0 1.0 25 Q9UJS0,P0DP25,P46934,Q9UBV8 4 +Anaphase promoting complex dependent catabolic process 0.3015873015873149 0.2096043984401297 0.8339764464437514 1.0 1.0 12 Q12834,Q16763,P53350,Q9UJX5,P30260,Q9UJX3,Q13042,Q9UJX2,Q9H1A4,Q9UJX4,P24941 11 +Positive regulation of production of molecular mediator of immune response 0.2787632565643277 0.2091439769213077 0.8343358451155864 1.0 1.0 23 P43246,O96028,Q12888,Q7Z434,P04439,P14174,Q96EB6,Q5RKV6,Q5UIP0 9 +Embryo implantation 0.3256445581937472 0.2090710624711374 0.8343927643036266 1.0 1.0 10 Q8IZL8,Q07021 2 +Labyrinthine layer development 0.3255181250441321 0.2085687819939258 0.8347848829410742 1.0 1.0 10 P31749 1 +Glutamate biosynthetic process 0.5171281196196897 0.2081762584766135 0.8350913454842788 1.0 1.0 3 P00367 1 +Aspartate transmembrane transport 0.5171281196196897 0.2081762584766135 0.8350913454842788 1.0 1.0 3 Q9UJS0 1 +Positive regulation of endocytosis 0.2827001526261463 0.2080353358130879 0.8352013768963633 1.0 1.0 22 P41440,P22681,Q96PU5,P50897,P61978 5 +Response to human chorionic gonadotropin 0.510503597122298 0.2079730635632959 0.8352499996533234 1.0 1.0 2 P48506 1 +Regulation of double strand break repair via homologous recombination 0.2760476385060333 0.2077401344789421 0.8354318784495727 1.0 1.0 27 Q9NRR5,P09874,Q96B01,P35637,Q7Z4V5,O95619 6 +Lymphocyte activation 0.2431903598844614 0.2075895679196213 0.8355494505236911 1.0 1.0 109 P46379,P49366,P12956,P04439,Q96EY1,Q00577,Q9HCL2,Q9BXW9,P00813,P31749,P24390,Q04721,O96005,Q9UQ84,P30825,Q92830,Q96IZ0,O96028,P05771,P55327,Q66K64,P14174,Q5RKV6,P78318 24 +Xenophagy 0.4228860689066419 0.2075383814550738 0.8355894210515193 1.0 1.0 4 Q6UWE0 1 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.29458772333167 0.206143232911665 0.8366790289466663 1.0 1.0 18 Q96RU2,P14174,P46379,P61978 4 +Regulation of protein localization to cilium 0.393903943739075 0.2060031797695723 0.8367884274818496 1.0 1.0 5 Q10713 1 +Dendrite morphogenesis 0.26372618331102 0.2059534594362032 0.8368272658677436 1.0 1.0 35 P46934 1 +Mitochondrial protein catabolic process 0.5093525179856075 0.205472982985062 0.8372026042199023 1.0 1.0 2 Q9UG56 1 +Smooth muscle cell chemotaxis 0.5090647482014347 0.204850830545457 0.8376886719956145 1.0 1.0 2 O94813 1 +Regulation of smooth muscle cell chemotaxis 0.5090647482014347 0.204850830545457 0.8376886719956145 1.0 1.0 2 O94813 1 +Monoacylglycerol metabolic process 0.5087769784172625 0.2042298262134373 0.8381739045728946 1.0 1.0 2 Q8N2K0 1 +Monoacylglycerol catabolic process 0.5087769784172625 0.2042298262134373 0.8381739045728946 1.0 1.0 2 Q8N2K0 1 +Positive regulation of erbb signaling pathway 0.3542698785608731 0.2041644883451718 0.8382249610384513 1.0 1.0 7 P37198 1 +Polyol biosynthetic process 0.3002100676430695 0.2035688331847745 0.8386904506292725 1.0 1.0 12 P00374 1 +Cardiac septum development 0.3000613390770025 0.2035354029302081 0.8387165772104042 1.0 1.0 13 O96028,Q04721 2 +Secretion 0.2337084663501529 0.2033703777746052 0.8388455511064241 1.0 1.0 165 Q13505,Q4J6C6,Q9BRK5,Q99808,Q8N183,P22681,Q6WKZ4,Q12765,P00813,P00367,P53367,Q9H7Z7,Q5SQN1,P09601,O95721,Q16850,O00233,Q6ZWJ1,P0DP25,P55327,P53985,P14174,Q96PC5,P50897,P05771 25 +Regulation of platelet derived growth factor receptor signaling pathway 0.4211869683426215 0.2031152086796089 0.8390449846909545 1.0 1.0 4 P22681 1 +Regulation of small gtpase mediated signal transduction 0.2580779094284973 0.2019731814686315 0.8399376901890976 1.0 1.0 43 P16949,O95630,Q04721,Q9NUQ9,P41440,P22681,P46108,Q4VCS5,Q13501,Q8N6T3,Q15058,P37198 12 +Cytokine mediated signaling pathway 0.2525886193868899 0.2015667793558181 0.8402554183487583 1.0 1.0 51 Q14166,P18031,Q13546,Q9Y5A9,Q8TCT8,Q7Z739,Q9UKG1,Q9UJ41,Q01804,Q16739,P22681,Q9Y3Z3,Q96EB6,P31749 14 +Intestinal epithelial cell differentiation 0.5073381294963988 0.2011420435409503 0.8405875077469085 1.0 1.0 2 P04818 1 +Intestinal epithelial cell development 0.5073381294963988 0.2011420435409503 0.8405875077469085 1.0 1.0 2 P04818 1 +Phosphate ion transport 0.5133147238317698 0.1999082189641293 0.8415523623875525 1.0 1.0 3 Q9UBX3 1 +Phosphate ion transmembrane transport 0.5133147238317698 0.1999082189641293 0.8415523623875525 1.0 1.0 3 Q9UBX3 1 +Regulation of release of cytochrome c from mitochondria 0.2992754720663175 0.1995036556780693 0.8418687840153407 1.0 1.0 12 O60313,P31749,P02545,O14737 4 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.2874443314354117 0.1957704841259234 0.8447898132683938 1.0 1.0 20 Q8N163,Q9UL15,P46379,O43765 4 +Negative regulation of neuron apoptotic process 0.2741445927292754 0.1950205772972849 0.8453768385502125 1.0 1.0 27 O75312,O95630,P48681,P51858,P09601,P50897,Q15233,Q01105 8 +Leukocyte mediated cytotoxicity 0.2968967338402367 0.1946973792287735 0.8456298637235036 1.0 1.0 15 P04439,P07437,P46108,Q9NUQ9 4 +Aminoglycan metabolic process 0.2942513713326791 0.1944845845893198 0.8457964649992147 1.0 1.0 17 Q8N6G5,P06865,P16278,Q8NCH0,Q96L58,P54802 6 +Cellular response to follicle stimulating hormone stimulus 0.5106505469199633 0.1942360561879023 0.8459910516965177 1.0 1.0 3 P48506,P16435 2 +Response to follicle stimulating hormone 0.5106505469199633 0.1942360561879023 0.8459910516965177 1.0 1.0 3 P48506,P16435 2 +Nadh dehydrogenase complex assembly 0.2684629777908166 0.1934662248757705 0.8465938549758723 1.0 1.0 31 Q9H061,Q15070,O75489,O43676,O95169,Q8N183,Q9P0J0,O96000 8 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.2973410263566698 0.1932882539488243 0.846733224865182 1.0 1.0 14 Q9Y2U8,Q96EB6,Q92896 3 +Membrane fission 0.4163177238058819 0.1906764452501726 0.8487790940565336 1.0 1.0 4 Q9H444 1 +Protein o linked glycosylation 0.2948997648909115 0.1903661123906101 0.8490222504732867 1.0 1.0 16 O60502,Q9H9S5 2 +Regulation of leukocyte differentiation 0.2696052439704859 0.1898166858809613 0.8494527801641083 1.0 1.0 30 Q04721,Q13546,O00165,Q9BXW9,P12956,P00813,Q92830 7 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.2968395789008113 0.1892681579625763 0.8498826505127137 1.0 1.0 13 P09601,Q8IWB1 2 +Positive regulation of ion transport 0.2566016008509138 0.1889518960748113 0.8501305189154704 1.0 1.0 43 P08183,P30536,P31749 3 +Regulation of chromatin binding 0.365191898373684 0.1875397889424584 0.8512374299979835 1.0 1.0 6 O14981 1 +Positive regulation of synaptic transmission 0.2857633263389582 0.1866106696306065 0.8519659005506284 1.0 1.0 20 P05067,P41440 2 +Positive regulation of torc1 signaling 0.4143391880218826 0.1857235778040457 0.8526615375826234 1.0 1.0 4 Q9NWS0,Q9P2J5,Q96EE3 3 +Entry into host 0.2688959935411062 0.1848172326400943 0.8533723910123758 1.0 1.0 30 Q9BTY2,Q14108,P22681,O15118,Q8WTV0 5 +Double strand break repair via nonhomologous end joining 0.2738528896457177 0.1833450855804261 0.8545272607352079 1.0 1.0 25 P12956,O96028 2 +Negative regulation of ion transport 0.2851395154036729 0.1832379643956513 0.8546113073444515 1.0 1.0 20 P21796,P46934 2 +Protein retention in golgi apparatus 0.4984172661870467 0.1826420987336459 0.8550788498884629 1.0 1.0 2 Q9H4A6 1 +Ribosomal small subunit export from nucleus 0.3295783802626588 0.1824853404042102 0.855201857865467 1.0 1.0 8 Q96GA3,Q99567 2 +Myelin assembly 0.3635724531914885 0.1824605451725952 0.8552213149611667 1.0 1.0 6 Q9NR77 1 +Negative regulation of exocytosis 0.3285069243189816 0.1787126796439688 0.8581633125553945 1.0 1.0 8 P09601,Q9UJ41 2 +Nuclear chromosome segregation 0.2327359372577944 0.1786689087313564 0.8581976835472451 1.0 1.0 126 O43663,P46379,Q8IXJ6,Q9ULX6,Q7Z5K2,Q13123,Q96JM3,Q9UJX3,Q29RF7,P25054,Q9NTI5,Q9H444,Q9BXW9,Q9HD42,Q15058,P37198,Q9NQS7,P23246,Q96EA4,Q92791,Q9BVS4,O43823,Q9BTX1,Q13561,Q86Y91,Q9BS16,Q96BK5 27 +Protein localization to golgi apparatus 0.3178004749226616 0.1786301000016919 0.8582281582230507 1.0 1.0 10 Q8TD16,Q8IWJ2,P20340,O14976 4 +Positive regulation of metaphase anaphase transition of cell cycle 0.3176831619617427 0.1781861684071194 0.8585767719091562 1.0 1.0 10 Q14674,Q9UJX5,Q9UJX3,Q9UJX2,Q9UJX4 5 +Germ cell development 0.2550098483476054 0.1750594887621913 0.8610328899370903 1.0 1.0 43 Q8IXJ6,Q08J23,Q9Y5A9,Q96PU8,P31749 5 +Antigen processing and presentation of exogenous peptide antigen 0.3828961492172181 0.1747818769425847 0.8612510292322062 1.0 1.0 5 Q9UIQ6 1 +Smooth muscle cell differentiation 0.3454287041470729 0.174667701931221 0.8613407477087516 1.0 1.0 7 Q53EL6 1 +Regulation of transmembrane transport 0.241758725058136 0.1741304801314069 0.8617629194320404 1.0 1.0 81 P31751,P08183,P21796,Q16625,O75844,P31749,P05067,P46934,P05771 9 +Peptidyl amino acid modification 0.2611964900652044 0.1720347508210423 0.8634102090578286 1.0 1.0 298 Q96AY3,O75718,Q8IXJ6,O95302,Q9H7B4,P49366,Q9Y680,Q15257,O95684,Q5VZE5,Q00403,O00165,Q9NTG7,Q9UGN5,Q6P2P2,P49761,P31749,Q01105,P31751,P51812,Q15418,Q5T5X7,O15460,Q92791,P13674,Q13432,Q92830,O96028,P09874,P0DP25,Q9NWM8,O75844,P05067,P05771 34 +Regulation of steroid hormone biosynthetic process 0.4926618705035933 0.1712988567564609 0.8639887793541519 1.0 1.0 2 P16435 1 +Regulation of hormone biosynthetic process 0.4926618705035933 0.1712988567564609 0.8639887793541519 1.0 1.0 2 P16435 1 +Regulation of glucocorticoid metabolic process 0.4926618705035928 0.1712988567564601 0.8639887793541525 1.0 1.0 2 Q9UNE7 1 +Regulation of fibroblast migration 0.3041535459679037 0.1700529836753711 0.8649684684603585 1.0 1.0 11 P31749,O95429 2 +Negative regulation of response to dna damage stimulus 0.2702892826222243 0.1697471262193863 0.8652090104800987 1.0 1.0 27 Q9NRR5,Q8N163,Q9UBB9,P14174 4 +Gland morphogenesis 0.2918079869339754 0.1676065732988719 0.8668927996160225 1.0 1.0 13 Q15418 1 +Behavioral response to cocaine 0.4897841726618662 0.165802153378168 0.8683126514297612 1.0 1.0 2 Q96KQ7 1 +Regulation of immunoglobulin production 0.2895766519009533 0.1654827782656591 0.8685640039063445 1.0 1.0 16 P43246,O96028,Q12888,Q96FV9,Q9NQT5,Q5RKV6,Q5UIP0 7 +Neuronal action potential 0.3790322580645208 0.1643083059354595 0.8694884433681322 1.0 1.0 5 Q12955,Q06787,P04062,Q7Z406 4 +Regulation of cellular response to growth factor stimulus 0.2525165066882909 0.1627139818450435 0.870743637786783 1.0 1.0 44 Q04721,P18031,Q13573,Q9UPN9,Q9P266,Q8N0X7,O14936,Q9UNE7,Q9Y2U8,P62942,O14964,Q96EB6,Q14318,Q92896,P46934,P05771 16 +Centromere complex assembly 0.3022607338093686 0.1626825667479237 0.8707683738409064 1.0 1.0 11 Q9BS16 1 +Natural killer cell mediated immunity 0.3021064424074152 0.1620861308892487 0.8712380277223004 1.0 1.0 11 P04439,P07437,P46108 3 +Regulation of nucleotide biosynthetic process 0.3231893996378915 0.1603753928807862 0.872585372346719 1.0 1.0 8 Q15118,P09874,Q15120 3 +Positive regulation of response to biotic stimulus 0.2577219248781194 0.1589821122003652 0.8736829669756485 1.0 1.0 35 Q9NW08,P23246,Q9Y4E8,Q8WXF1,Q7Z434,P12956,P14174,P43243,Q96PK6,Q15233,O60828,P07948 12 +Negative regulation of steroid metabolic process 0.4928036845135158 0.1584831762051487 0.8740760765674347 1.0 1.0 3 O94905,O75477 2 +Positive regulation of protein catabolic process 0.2388458252003341 0.1572958334959212 0.875011703774373 1.0 1.0 76 Q9UII2,O75150,O43765,O43847,P25054,P46379,Q8IXJ6,Q96JB5,Q8NEZ5,Q9P0J0,Q96PU5,P31749,Q96HY6,P46934 14 +Negative regulation of ion transmembrane transporter activity 0.2885941647338349 0.1571000229803111 0.8751660194715911 1.0 1.0 15 P46934 1 +Protein localization to nuclear envelope 0.3219942812008671 0.1563437725536754 0.875762055026386 1.0 1.0 8 Q9NVM9,Q9BZF1,Q8NFQ8,Q7Z3B4 4 +Heart valve morphogenesis 0.3394812680115171 0.1557085289486915 0.8762627740468267 1.0 1.0 7 Q04721,Q13464,P06400,O75116,P42345,O94813 6 +Mitotic g2 dna damage checkpoint signaling 0.2873165422033943 0.1552021628194088 0.876661943267099 1.0 1.0 16 Q96JB5,Q6NUQ1,Q9HAW4,P38398 4 +Chondrocyte differentiation 0.3002304154086339 0.1548870807206377 0.8769103388237038 1.0 1.0 11 Q15043 1 +Positive regulation of neurotransmitter transport 0.4899251583189231 0.1530865242528769 0.878330042702328 1.0 1.0 3 P20337,P05556 2 +Skin epidermis development 0.2881650329753938 0.1530588355561842 0.8783518777701476 1.0 1.0 14 O75844 1 +Response to platelet derived growth factor 0.3108152555270729 0.152798057022833 0.8785575300139996 1.0 1.0 10 Q96A49 1 +Cellular monovalent inorganic cation homeostasis 0.2682576859599462 0.152078881352678 0.8791247206899828 1.0 1.0 26 Q15904,P06576,Q93050,O75503,Q8N511,O75787,Q96PU5,P50897 8 +Ph reduction 0.2876969015890471 0.1510781076881079 0.8799141017981158 1.0 1.0 14 Q93050,O75503,Q8N511,O75787,P50897 5 +Gastrulation with mouth forming second 0.3737073884087749 0.1502986346941306 0.8805290101113936 1.0 1.0 5 Q4VCS5 1 +Peptide transport 0.2562995349260276 0.1495205066030338 0.8811429293186075 1.0 1.0 36 O00233,Q6ZWJ1,Q8N183,P53985,P33527,P00367 6 +Protein deneddylation 0.3372786132794962 0.1488725528450404 0.8816541994895244 1.0 1.0 7 Q92905,Q99627 2 +Intracellular estrogen receptor signaling pathway 0.272388497317605 0.1485982241370667 0.8818706743857385 1.0 1.0 22 P09874,P38398,Q92841,Q9P253,Q86X55,Q96HY6 6 +Protein autophosphorylation 0.2508626817829459 0.1483796756376985 0.8820431390061318 1.0 1.0 44 P0DP25,P31749,Q9BVS4,Q7KZI7,P49761,Q05682 6 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.2984429475815563 0.1481197109324215 0.8822482939529324 1.0 1.0 11 Q9Y2U8,Q92896 2 +Positive regulation of protein targeting to membrane 0.3094884309728392 0.1480318454661149 0.8823176360568405 1.0 1.0 10 P31751 1 +Multi organism reproductive process 0.2305145978214762 0.1470339337546622 0.8831052361278522 1.0 1.0 165 O75718,P46379,Q8IXJ6,P16104,Q9Y5A9,Q96EB6,Q14320,Q9BQE5,P41440,Q08J23,Q15067,Q96PU8,Q9BXW9,Q07021,P00813,P31749,Q15363,O95394,P45880,Q9UIQ6,Q01085,Q9BTX1,Q14157,Q7Z7E8,Q96EP5,Q9H2V7,P41208,Q8IZL8,Q07666,P05067 30 +Regulation of protein localization to cell cortex 0.3979268643823793 0.1469511005844305 0.8831706172676683 1.0 1.0 4 P11171,Q14980,O43491 3 +Membrane repolarization 0.3189806956775716 0.1463263747381917 0.8836637459107102 1.0 1.0 8 O75844 1 +Regulation of dna dependent dna replication 0.2717936803018835 0.1453045356897017 0.8844704337706943 1.0 1.0 22 Q9BRT9,O75844,O95785 3 +Apoptotic process involved in morphogenesis 0.3970129948816877 0.1449154853341744 0.8847775999701797 1.0 1.0 4 P30154 1 +Spindle elongation 0.3503313166234552 0.1427726773116027 0.886469716329519 1.0 1.0 6 O43663,Q02241,Q14980,O95239,Q9H0H5 5 +Glycosaminoglycan catabolic process 0.3707046804660486 0.1426181908130548 0.8865917301544488 1.0 1.0 5 P16278 1 +Aminoglycan catabolic process 0.3707046804660486 0.1426181908130548 0.8865917301544488 1.0 1.0 5 P16278 1 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.2465242726717652 0.1423362953445982 0.8868143788303384 1.0 1.0 48 Q9UII2,O75150,O43765,P46379,Q8IXJ6,Q96JB5,Q8NEZ5,P31749 8 +Sphingomyelin catabolic process 0.4765467625899235 0.1420213051740678 0.8870631771659943 1.0 1.0 2 Q05655 1 +Dendrite arborization 0.476258992805751 0.141531738924231 0.8874498883582285 1.0 1.0 2 Q9UL54 1 +Er overload response 0.3698156682027693 0.1403749143788058 0.888363777012998 1.0 1.0 5 P04637,Q9UM00,Q96A33,O76024 4 +Negative regulation of androgen receptor signaling pathway 0.3692396313364179 0.1389288934072467 0.8895063387299991 1.0 1.0 5 Q96EB6,P51532,Q13547,O75376 4 +Antiviral innate immune response 0.3692396313364114 0.1389288934072307 0.8895063387300117 1.0 1.0 5 Q92667,Q9H078,Q99623,Q9NVI7 4 +Export from cell 0.2257065319434571 0.1380318085825077 0.8902152785431636 1.0 1.0 152 Q32P28,Q92905,P08183,Q4J6C6,Q9BRK5,Q8N183,P22681,Q6WKZ4,Q12765,P00367,P53367,Q5SQN1,P09601,O95721,Q16850,O00233,Q6ZWJ1,P0DP25,Q7Z7E8,P53985,P14174,Q96PC5,P33527,P50897,P05771 25 +Axoneme assembly 0.3932598792296778 0.1366939752611172 0.8912726918752896 1.0 1.0 4 Q9UPN4 1 +Hormone mediated signaling pathway 0.2458600242072915 0.1363211838765141 0.8915673778964863 1.0 1.0 48 P09874,Q86X55,O15173,Q9UKG1,P04150,P38398,Q92841,Q9P253,Q96EB6,Q9UER7,Q96HY6,P42785,P46934 13 +Positive regulation of lymphocyte apoptotic process 0.4722302158273336 0.1347998535779591 0.8927701216091162 1.0 1.0 2 Q07812 1 +Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia 0.4722302158273337 0.1347998535779591 0.8927701216091162 1.0 1.0 2 Q06330 1 +Regulation of nucleocytoplasmic transport 0.2455782953911636 0.1346152332031074 0.892916096886414 1.0 1.0 51 O75312,P50402,P49790,Q08J23,Q9BVL2,Q9ULX6,Q9BWF3,Q14978,P35658,Q7Z434,Q9BVS4,Q96ST2,Q13148,Q07666,P46934 15 +Regulation of membrane protein ectodomain proteolysis 0.3917280414314728 0.1334025626373666 0.8938750188323914 1.0 1.0 4 Q9Y5X1,O43847 2 +Detection of visible light 0.471079136690643 0.1329182290670742 0.8942580501122108 1.0 1.0 2 Q15555 1 +Phototransduction visible light 0.471079136690643 0.1329182290670742 0.8942580501122108 1.0 1.0 2 Q15555 1 +Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 0.471079136690643 0.1329182290670739 0.894258050112211 1.0 1.0 2 Q07812 1 +Regulation of tor signaling 0.2822480221263504 0.1327839323096785 0.8943642619851575 1.0 1.0 16 Q96EB6,O75844 2 +Positive regulation of protein localization to cell periphery 0.275342825992776 0.1322253928153937 0.8948060168936975 1.0 1.0 20 P31749,Q13501,O00264 3 +Negative regulation of cell differentiation 0.2391897639210551 0.1317089959118411 0.8952144698023585 1.0 1.0 85 P67809,Q8IXJ6,Q99523,Q9Y5A9,P30536,Q53EL6,Q15154,Q96G23,Q15051,P05067,Q8N4Q0 11 +Sugar mediated signaling pathway 0.3901526058162972 0.1300564301374825 0.8965217809752923 1.0 1.0 4 Q9NWS0,P51532,Q12824 3 +Carbohydrate mediated signaling 0.3901526058162972 0.1300564301374825 0.8965217809752923 1.0 1.0 4 Q9NWS0,P51532,Q12824 3 +Autophagosome organization 0.2639601938997478 0.1297682923749132 0.896749749767014 1.0 1.0 27 Q9H0U4,Q7Z3C6,Q9UNZ2,Q9Y4P1,P16615,Q9H444,O00189,Q8TBX8,Q86Y82,Q6UWE0 10 +Pyroptosis 0.4763960852043582 0.129113169971092 0.8972681011058095 1.0 1.0 3 O60443,Q08211 2 +Regulation of jnk cascade 0.2803064948829473 0.1288493281208965 0.8974768726229525 1.0 1.0 17 P05067,Q53EL6,Q13546 3 +Regulation of hair cycle 0.4682014388489167 0.1282951499427654 0.8979154031738061 1.0 1.0 2 Q14980 1 +Dicarboxylic acid metabolic process 0.2482979389668726 0.1265119144340797 0.8993267184686504 1.0 1.0 44 P00374,P41440,P48735,P31939,O14734,Q9H9P8,P00367 7 +Tube development 0.2243523240371594 0.1264934213734883 0.8993413562030641 1.0 1.0 150 Q96AY3,P06576,P42892,Q9P266,Q96PU8,P09960,Q92830,Q96JM3,P09601,P00813,P31749,P05771,P42785,Q9NZ08,O94788 15 +Branching involved in blood vessel morphogenesis 0.3881370572991655 0.1258332537411181 0.8998639183022137 1.0 1.0 4 Q96T37,Q14344,Q13043 3 +Digestive tract morphogenesis 0.3881370572991652 0.1258332537411175 0.8998639183022141 1.0 1.0 4 Q6KC79,P35453,Q9HCM4 3 +Mesenchymal to epithelial transition 0.3881370572991637 0.1258332537411142 0.8998639183022168 1.0 1.0 4 P80723,P42224,Q9BRX2 3 +Mesonephros development 0.3881370572991616 0.1258332537411099 0.8998639183022201 1.0 1.0 4 Q13418,P80723,O94813 3 +Integrated stress response signaling 0.3638940877738726 0.1257934995874529 0.8998953874765683 1.0 1.0 5 Q15363 1 +Perk mediated unfolded protein response 0.3638940877738726 0.1257934995874529 0.8998953874765683 1.0 1.0 5 Q15363 1 +Muscle cell proliferation 0.2628323025263545 0.1228500059848682 0.9022258750831644 1.0 1.0 27 P12956,P31749,Q5VZE5 3 +Protein k63 linked deubiquitination 0.2803373920563762 0.122744236051506 0.9023096333919988 1.0 1.0 12 Q01804 1 +Glycolytic fermentation 0.4723661485319331 0.1224164946922876 0.9025691758822983 1.0 1.0 3 Q9NQ88,O75746 2 +Fermentation 0.4723661485319331 0.1224164946922876 0.9025691758822983 1.0 1.0 3 Q9NQ88,O75746 2 +Positive regulation of synapse maturation 0.4641726618704997 0.122016501265477 0.9028859497976354 1.0 1.0 2 Q9UJX6 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.2799045440280847 0.1211206327071211 0.9035954869505248 1.0 1.0 12 O60506 1 +Vesicle targeting rough er to cis golgi 0.2910494382996061 0.1211003940037485 0.903611517104129 1.0 1.0 11 Q15363,O15027,Q9UBV8 3 +Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery 0.3616129431421192 0.1203449628150462 0.9042098877304792 1.0 1.0 5 P57740 1 +Positive regulation of gluconeogenesis 0.38526728782842 0.1199323337810051 0.9045367506771184 1.0 1.0 4 Q92830 1 +Hepatocyte apoptotic process 0.4621582733812904 0.1189615191532605 0.9053058424984926 1.0 1.0 2 Q13043 1 +Post translational protein modification 0.2792939157252128 0.1188405103955549 0.9054017134317645 1.0 1.0 12 O60725,Q92905,O75718,Q32P28 4 +Regulation of sequestering of triglyceride 0.3846818312697891 0.118744703046409 0.9054776191636702 1.0 1.0 4 Q96AD5,Q9BZF1,O60664 3 +Sequestering of triglyceride 0.3846818312697891 0.118744703046409 0.9054776191636702 1.0 1.0 4 Q96AD5,Q9BZF1,O60664 3 +Regulation of morphogenesis of a branching structure 0.3843938957673478 0.1181626269717152 0.905938801805068 1.0 1.0 4 P35222,Q9NQC3,P35453 3 +Amine catabolic process 0.3839846828618704 0.1173376713020832 0.906592473821472 1.0 1.0 4 P49366 1 +Negative regulation of single stranded viral rna replication via double stranded dna intermediate 0.3600230414746636 0.1166033183514121 0.9071744080018064 1.0 1.0 5 Q15047,Q9UK61,Q9Y6X9,Q99549 4 +Myeloid cell apoptotic process 0.3593958976974075 0.1151400646089342 0.9083341040944934 1.0 1.0 5 P14174 1 +Regulation of myeloid cell apoptotic process 0.3593958976974075 0.1151400646089342 0.9083341040944934 1.0 1.0 5 P14174 1 +Regulation of g protein coupled receptor signaling pathway 0.277034488489 0.1144553876397478 0.9088768094331972 1.0 1.0 17 Q15043,P00813 2 +Positive regulation of store operated calcium channel activity 0.4587050359712182 0.1138544901239343 0.9093531425118976 1.0 1.0 2 Q9P246 1 +Regulation of store operated calcium channel activity 0.4587050359712182 0.1138544901239343 0.9093531425118976 1.0 1.0 2 Q9P246 1 +Activation of store operated calcium channel activity 0.4587050359712182 0.1138544901239343 0.9093531425118976 1.0 1.0 2 Q9P246 1 +Store operated calcium entry 0.4587050359712182 0.1138544901239343 0.9093531425118976 1.0 1.0 2 Q9P246 1 +Regulation of cell cycle g1 s phase transition 0.2443524358716666 0.1124407752163046 0.9104739263519468 1.0 1.0 46 P25054,Q6ZWJ1,Q9UKG1,Q9NPI1,Q9UL46,P42575,P61289,Q8N7H5,Q6Y7W6,Q96DY7,P31749,Q96HY6 12 +Meiotic chromosome segregation 0.2619683819297876 0.1108522233642672 0.9117335322458896 1.0 1.0 24 Q92791,Q9BTX1,Q9BXW9 3 +Positive regulation of myeloid leukocyte cytokine production involved in immune response 0.307639884831001 0.1105839144314223 0.9119463036672056 1.0 1.0 8 Q96EB6,P14174 2 +Synaptic vesicle membrane organization 0.3385921225170744 0.1104384980403781 0.9120616228253507 1.0 1.0 6 O95721,Q5SQN1 2 +Regulation of synapse maturation 0.4643062751870859 0.109634170899285 0.912699509538258 1.0 1.0 3 Q9UJX6,P63104 2 +Response to ether 0.3800748632306305 0.1095912667379329 0.9127335370714156 1.0 1.0 4 Q6PKG0,Q14103,Q9H4A6 3 +Regulation of mrna binding 0.3236758030140574 0.1089516589904422 0.9132408325329036 1.0 1.0 7 Q86X55,P50750 2 +Pattern recognition receptor signaling pathway 0.2508352416035462 0.1084111376476779 0.9136695666424584 1.0 1.0 36 P51812,P41440,Q01804,Q07021,Q86UT6 5 +Spindle assembly involved in female meiosis 0.4634427173287114 0.1083128311015199 0.9137475447492972 1.0 1.0 3 O14965,O95067 2 +Meiotic cell cycle phase transition 0.4634427173287087 0.1083128311015157 0.9137475447493004 1.0 1.0 3 O95067,P33981 2 +Macrophage activation 0.3066698247013167 0.1076731781001599 0.914254946567194 1.0 1.0 8 P05067 1 +Regulation of inflammatory response 0.2458713732684927 0.1062423763472979 0.915390049723562 1.0 1.0 44 Q13546,P28070,Q53EL6,Q9BXW9,P00813,P33527,P05067 7 +Regulation of intracellular estrogen receptor signaling pathway 0.2742135021810389 0.1023676616176074 0.9184648510874452 1.0 1.0 17 P09874,Q96HY6,P38398,Q9P253 4 +Trophoblast cell migration 0.4592555604128353 0.1020377604363666 0.918726702994742 1.0 1.0 3 Q07021 1 +Monovalent inorganic cation homeostasis 0.257704907343139 0.1020185263945758 0.9187419698704552 1.0 1.0 29 Q15904,P06576,Q93050,O75503,Q8N511,O75787,Q96PU5,P50897 8 +Lamellipodium morphogenesis 0.3350533410284608 0.101235355398681 0.919363631326834 1.0 1.0 6 Q14155,Q13596,O60749 3 +Renal tubule development 0.3349874247172923 0.1010663563035704 0.9194977850404282 1.0 1.0 6 Q04721 1 +Sphingomyelin metabolic process 0.3336214347450383 0.0975842275174929 0.922262449340703 1.0 1.0 6 O15269,Q05655,P22059,O15270,Q9NXE4 5 +Negative regulation of endocytosis 0.2735033538618064 0.0962561463826471 0.9233171394177512 1.0 1.0 16 P05067 1 +Cellular glucose homeostasis 0.2510197955040821 0.0954067677467033 0.9239917407173605 1.0 1.0 33 Q6ZWJ1,Q99808,Q8N183,Q15043,P62995,Q96EB6 6 +Telomere maintenance via recombination 0.3327571305099446 0.0954007769136007 0.9239964990065616 1.0 1.0 6 Q96SB8,Q92889,Q92878,Q8IY18,P18887 5 +Dendritic cell differentiation 0.3321891286656699 0.0939742350324735 0.9251296236094046 1.0 1.0 6 Q04721 1 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.2398400131894334 0.0939243072351196 0.9251692848071644 1.0 1.0 56 Q9NRR5,O43765,P46379,Q8IXJ6,Q8N163,Q8NEZ5,P31749,Q9UL15 8 +Asymmetric neuroblast division 0.4533678756476552 0.0935820664954052 0.9254411559512904 1.0 1.0 3 Q92974,Q96N67 2 +Neuroblast division 0.4533678756476552 0.0935820664954052 0.9254411559512904 1.0 1.0 3 Q92974,Q96N67 2 +Response to transforming growth factor beta 0.2478235684819792 0.092811810168695 0.9260530683540212 1.0 1.0 39 P09874,P04150,O14737,Q9Y2U8,P46108,Q96EB6,Q92896 7 +Signal transduction in response to dna damage 0.2396350244959346 0.0919848136806281 0.926710105360598 1.0 1.0 56 Q6NUQ1,P16104,O75844,Q96JB5,Q8N163,Q96RU2,P38398,Q9BXW9,P42575,P14174,Q6Y7W6,O75663,Q9HAW4,Q96EB6 14 +Presynaptic active zone organization 0.4516407599308975 0.0911827350666162 0.9273473932202196 1.0 1.0 3 P56545,P20810 2 +Regulation of chromosome condensation 0.300951282790427 0.0909939548919092 0.9274973944277004 1.0 1.0 8 Q9BPX3,Q15003,Q9NTJ3,Q7Z5K2,O95347,O60264,Q9UIG0 7 +Release of cytochrome c from mitochondria 0.2714038789184619 0.0906306098253948 0.927786108891676 1.0 1.0 17 P31749,Q9Y3D6,P02545,O14737 4 +Positive regulation of double strand break repair 0.2642025272867869 0.0900681509274646 0.928233058202722 1.0 1.0 21 Q7Z4V5,P09874,O95619,P35637 4 +Aspartate family amino acid biosynthetic process 0.271273624344211 0.0900309454564612 0.928262623757896 1.0 1.0 12 Q13126,Q9BV57 2 +Cellular response to vascular endothelial growth factor stimulus 0.2963796713652797 0.0895634472769827 0.9286341324735684 1.0 1.0 9 P31749 1 +Rig i signaling pathway 0.271777880248932 0.0893804148150507 0.9287795878804124 1.0 1.0 13 Q07021,Q9Y4E8,Q86UT6 3 +Positive regulation of protein localization to cell cortex 0.449337938975233 0.0880405243204359 0.929844467425564 1.0 1.0 3 Q14980,O43491 2 +Circadian rhythm 0.2402295108996102 0.0866638759709294 0.9309386911433536 1.0 1.0 48 P29375,Q9Y2W1,P23246,Q8N163,Q03164,Q9BWF3,Q9NRV9,Q9BQG2,P54802,Q14103,Q13148,Q8WXF1,Q96EB6,Q15233,P43490 15 +Positive regulation of peptidyl tyrosine phosphorylation 0.2677701118281869 0.0863794297186444 0.9311647985103376 1.0 1.0 19 O00165,Q13432 2 +Positive regulation of erk1 and erk2 cascade 0.2703639351407583 0.0863637023465919 0.9311773004181894 1.0 1.0 17 Q04721,P05067,P14174 3 +Negative regulation of mitotic cell cycle 0.2344054788237847 0.086071996466005 0.9314091845746676 1.0 1.0 63 P43246,Q96BK5,P38398,Q13123,Q9NZJ0,P25054,Q9Y619,Q9BXW9,P33981,Q6NUQ1,Q96EA4,Q6Y7W6,Q96DY7,Q96JB5,Q9NPI1,P42575,Q9HAW4,O60566,P49454 19 +Macropinocytosis 0.4454433704435954 0.0828735773427936 0.9339520639772454 1.0 1.0 3 Q9UKG1 1 +Mitotic cell cycle checkpoint signaling 0.2397654092890101 0.0826809979099166 0.9341051946019034 1.0 1.0 48 Q6NUQ1,P25054,Q9Y619,Q96JB5,P38398,Q9BXW9,P33981,Q13123,Q96EA4,P42575,Q9NZJ0,Q6Y7W6,Q9HAW4,O60566,P49454 15 +Negative regulation of signal transduction by p53 class mediator 0.313022312445851 0.0805338885991025 0.9358126445516616 1.0 1.0 7 P14174 1 +Transcription initiation from rna polymerase ii promoter 0.2554351970190441 0.0791090888569431 0.936945854310063 1.0 1.0 27 P53999,Q9NPJ6 2 +Regulation of receptor catabolic process 0.3619349265764416 0.0768685779664519 0.9387280947133054 1.0 1.0 4 Q13614,P18031,Q96J02 3 +Regulation of defense response to virus 0.2663877054847683 0.074233206180185 0.940824824021616 1.0 1.0 18 O75844,Q07021,Q86UT6 3 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.3403067781342928 0.0740607597012404 0.9409620386979484 1.0 1.0 5 P14174 1 +Vitamin d metabolic process 0.4378238341968811 0.0732942415160119 0.9415719739815058 1.0 1.0 3 Q99538,P38435 2 +Positive regulation of mitochondrion organization 0.254814004527139 0.0721410976475125 0.9424896202175193 1.0 1.0 25 Q9UII2,P21796,Q9Y3D6,P27544 4 +Negative regulation of b cell activation 0.3096619937762871 0.072102548721056 0.9425202979210124 1.0 1.0 7 Q96FV9,Q96IZ0 2 +Regulation of cell development 0.2351651173527335 0.0704410170098554 0.9438426454576668 1.0 1.0 94 P55209,Q9UQB8,Q04721,Q8IXJ6,Q9Y5A9,P30536,Q8NEZ5,Q15154,P46108,Q07021,Q96G23,P31749 12 +Cerebellar purkinje cell layer development 0.3088227123789776 0.0700369327144782 0.944164263742628 1.0 1.0 7 Q86U70,Q15058 2 +Dna dealkylation involved in dna repair 0.4224460431654628 0.069787383961467 0.9443628888347756 1.0 1.0 2 Q9C0B1 1 +Mucopolysaccharide metabolic process 0.2754558983401917 0.069460600843561 0.9446229928463734 1.0 1.0 11 Q8N6G5,Q96L58,Q8NCH0 3 +N terminal protein amino acid acetylation 0.2929491171568367 0.0690499747665705 0.9449498402822136 1.0 1.0 8 Q5VZE5 1 +Trna catabolic process 0.2851177130324371 0.0689214442191469 0.945052149086416 1.0 1.0 10 Q13868,Q08J23 2 +Proximal tubule development 0.4326629539748831 0.0671982980809173 0.9464238399986298 1.0 1.0 3 Q04721 1 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.4319731090825162 0.0664071559262027 0.9470536731757098 1.0 1.0 3 Q9UIQ6 1 +Negative regulation of histone h3 k9 methylation 0.3204969547982241 0.0660968295888518 0.947300734955262 1.0 1.0 6 Q96EB6 1 +Interleukin 6 production 0.2655652761278429 0.0655580160244523 0.9477297155267248 1.0 1.0 16 P05067,Q9UJ41,Q86UT6 3 +Positive regulation of translation in response to stress 0.4310461965036617 0.0653528669109243 0.9478930505642136 1.0 1.0 3 Q13217 1 +Positive regulation of translation in response to endoplasmic reticulum stress 0.4310461965036617 0.0653528669109243 0.9478930505642136 1.0 1.0 3 Q13217 1 +Regulation of leukocyte mediated cytotoxicity 0.2908954067252413 0.0636838393634287 0.949221972943612 1.0 1.0 8 P46108,P04439 2 +Positive regulation of pathway restricted smad protein phosphorylation 0.4294761082325644 0.0635897782935307 0.9492968710101556 1.0 1.0 3 P67870,P33981 2 +Second messenger mediated signaling 0.25264925215997 0.063396765466895 0.9494505628555768 1.0 1.0 27 P00813,Q9Y3D6,O75844,P0DP25 4 +Phosphatidylcholine acyl chain remodeling 0.4149640287769734 0.0627418303184191 0.9499720872142204 1.0 1.0 2 Q96N66 1 +Synaptic vesicle maturation 0.3526694973133077 0.0621864493437441 0.9504143534611212 1.0 1.0 4 P51790 1 +Negative regulation of protein kinase activity by regulation of protein phosphorylation 0.3340453692772273 0.0620544734888503 0.9505194519772532 1.0 1.0 5 Q96JB5,P06748 2 +Regulation of torc2 signaling 0.4141007194244561 0.0619707921538766 0.9505860917652982 1.0 1.0 2 Q9NWS0 1 +Negative regulation of cell cycle phase transition 0.2312329751616413 0.0605887191779057 0.9516867578107155 1.0 1.0 78 P43246,Q96K76,P16104,Q96BK5,Q8N163,P38398,Q13123,Q9NZJ0,P25054,Q9Y619,Q08J23,Q9BXW9,P33981,Q6NUQ1,Q96EA4,Q6Y7W6,Q96JB5,Q9NPI1,Q96RU2,P42575,O75663,Q9HAW4,O60566,P49454 24 +Endoplasmic reticulum organization 0.2410348673627874 0.0603137823724854 0.951905725184408 1.0 1.0 43 Q15363,Q15006,O43765,P46379,Q8NFQ8,O14976,O43681,O00429,Q9NQC3,O15027,Q15629,Q8NHH9,Q9NP72,Q8N4V1,Q9P2W9 15 +Negative regulation of organelle organization 0.2301966084201578 0.0601613746855563 0.9520271085010644 1.0 1.0 116 O60313,Q7Z5K2,P38398,Q13123,Q9NYB0,P16949,P25054,P02545,Q9NUQ9,P30536,Q9H444,P09651,P28289,Q96PK6,P31749,Q9ULW0,Q9H0A0,Q9NYL9,Q9Y3E1,P35611,Q96EA4,Q9UHB6,Q96DY7,Q92830,P09874,Q9UEY8,Q9NVN8,Q96BK5 28 +Regulation of myeloid leukocyte mediated immunity 0.2815830934148695 0.0588268180988468 0.9530900476909 1.0 1.0 10 Q7Z434,Q9UJ41,P09601 3 +Mirna metabolic process 0.2813438442245215 0.058156502728731 0.9536239678403072 1.0 1.0 10 Q92945,Q92841 2 +Regulation of chromatin organization 0.2547835397254357 0.0579168113936385 0.953814892044005 1.0 1.0 22 Q9UPP1,Q9UK61,Q8NEY8 3 +Regulation of tumor necrosis factor mediated signaling pathway 0.3167541502423212 0.0577769471374395 0.9539263010167448 1.0 1.0 6 Q13546 1 +U4 snrna 3 end processing 0.2883318523495846 0.0571388443356226 0.954434593647892 1.0 1.0 8 Q5RKV6,Q13868 2 +Myeloid leukocyte differentiation 0.2432562676259463 0.0552430152280695 0.9559448600407828 1.0 1.0 34 P09874,Q04721,Q13546,O00165,P05067 5 +Basement membrane assembly 0.4214162348877286 0.054984055437601 0.9561511664927294 1.0 1.0 3 O60568,O75122 2 +Branching morphogenesis of a nerve 0.4054676258992759 0.0547211766862855 0.956360598082173 1.0 1.0 2 Q9NQC3 1 +Sno s rna processing 0.2800613068199979 0.0545912660601733 0.9564640970580728 1.0 1.0 10 Q5RKV6,O95453,Q13868 3 +Regulation of kidney development 0.4051798561151032 0.0544936476845446 0.956541869484926 1.0 1.0 2 P80723 1 +Metanephric mesenchyme development 0.4051798561151032 0.0544936476845446 0.956541869484926 1.0 1.0 2 P80723 1 +Kidney mesenchyme development 0.4051798561151032 0.0544936476845446 0.956541869484926 1.0 1.0 2 P80723 1 +Transport of virus 0.3298203434443888 0.0543625618934748 0.9566463060067172 1.0 1.0 5 P52292,P49790 2 +Regulation of cellular response to osmotic stress 0.4199769717904305 0.0535245708237283 0.9573139540195756 1.0 1.0 3 Q92974,Q9BPX6 2 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.313778935192474 0.0513734373957903 0.9590279507028228 1.0 1.0 6 Q07021 1 +Positive regulation of myelination 0.4159470351180042 0.049560215995642 0.9604728506852428 1.0 1.0 3 Q9UPY3,O75746 2 +Positive regulation of calcium ion import 0.3985611510791323 0.0495031334630436 0.960518340120858 1.0 1.0 2 O14936 1 +Regulation of monocyte differentiation 0.3982733812949596 0.0492965212505874 0.9606829917890712 1.0 1.0 2 Q9UKV3 1 +Negative regulation of mitotic cell cycle phase transition 0.2357742466910878 0.0489204427996147 0.9609826973675836 1.0 1.0 53 Q6NUQ1,P25054,Q9Y619,Q96JB5,Q9NPI1,P38398,P33981,Q13123,Q96EA4,P42575,Q9NZJ0,P49454,Q6Y7W6,Q9HAW4,O60566,Q96BK5 16 +Negative regulation of release of cytochrome c from mitochondria 0.3126121368782402 0.0489129976527488 0.9609886306323794 1.0 1.0 6 P31749,P02545 2 +Female gamete generation 0.249977693994196 0.0487362154171611 0.9611295144261144 1.0 1.0 27 Q9Y5A9,Q96EB6,Q8IXJ6,Q12768 4 +Vesicle targeting 0.2498710229307114 0.0485185211290927 0.961303004097237 1.0 1.0 23 O95721,Q8N6H7,Q9UBV8 3 +Golgi to lysosome transport 0.3122726768568225 0.0482025544196855 0.9615548144234768 1.0 1.0 6 Q99523,O14976 2 +Leukocyte migration 0.2347718611302435 0.0470661546765105 0.9624605020846686 1.0 1.0 56 P00813,P46108,Q07021,P09601,Q00013,P31749,P05067 7 +Divalent inorganic cation homeostasis 0.2319799230133209 0.0460243659035434 0.963290829301532 1.0 1.0 61 Q8IWX8,P0DP25,Q15043,Q9Y3D6,Q9HD20,Q8NEW0,Q8IYU8,P05067,P05771 9 +Negative regulation of inflammatory response 0.2599538490505311 0.0460106324686268 0.9633017754012944 1.0 1.0 17 P28070,Q9UJ41,Q86UT6,P00813,P07948 5 +Basement membrane organization 0.3243087557603765 0.0448219497929051 0.9642492292683 1.0 1.0 5 O75122,Q7Z460,O60568,P05556 4 +Amyloid precursor protein metabolic process 0.2494025534468867 0.0445994967056474 0.9644265438329268 1.0 1.0 24 Q9NQX7,Q15392,Q96IZ0,Q9NY61 4 +Positive regulation of telomere capping 0.4104778353482883 0.0444632917514118 0.9645351119618006 1.0 1.0 3 Q14103,P28482 2 +Positive regulation of transcription elongation from rna polymerase ii promoter 0.2763195846553258 0.0444613275091652 0.9645366776519936 1.0 1.0 10 P35269,Q6P1J9,O60885,P50750,Q7KZ85,Q9Y5B9,O14776,P35222,Q9NYV4 9 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.2568357254323806 0.0436613357782215 0.9651743593874054 1.0 1.0 12 Q86WB0,P30154,P31749,Q13546 4 +Morphogenesis of an epithelial fold 0.3879136690647436 0.042408751514683 0.9661728519273703 1.0 1.0 2 P35453 1 +Epidermis morphogenesis 0.3879136690647437 0.0424087515146827 0.9661728519273708 1.0 1.0 2 O60568 1 +Positive regulation of fibroblast growth factor receptor signaling pathway 0.3879136690647437 0.0424087515146827 0.9661728519273708 1.0 1.0 2 Q9Y639 1 +Regulation of fibroblast growth factor receptor signaling pathway 0.3879136690647437 0.0424087515146827 0.9661728519273708 1.0 1.0 2 Q9Y639 1 +Regulation of neuron differentiation 0.2485255913113547 0.042036531878016 0.9664695756167704 1.0 1.0 23 Q8WUJ1 1 +Trans synaptic signaling by trans synaptic complex 0.3858992805755351 0.0411895528119186 0.9671447822544128 1.0 1.0 2 Q9Y639 1 +Positive regulation of nitric oxide synthase biosynthetic process 0.4052964881980254 0.0399283400691663 0.9681502570058192 1.0 1.0 3 Q02952,P43490 2 +Nitric oxide synthase biosynthetic process 0.4052964881980254 0.0399283400691663 0.9681502570058192 1.0 1.0 3 Q02952,P43490 2 +Positive regulation of histone phosphorylation 0.336368516759078 0.0396125266872607 0.9684020404262051 1.0 1.0 4 P50750 1 +Mitochondrion localization 0.2574562929917774 0.0389900436286274 0.9688983266124108 1.0 1.0 18 O60313,Q7KZI7,Q9NVT9,O75153,Q8IWA4,Q92830,Q9UH62 7 +Regulation of vasculature development 0.2403549698343992 0.0384717707871793 0.969311538463934 1.0 1.0 39 Q9P266,P38398,Q4VCS5,Q96JM3,P09601,Q9H2J4,Q96EB6,Q9NZ08,P05771 9 +Cell cycle g1 s phase transition 0.2262005973764284 0.0383299397620712 0.969424619841919 1.0 1.0 71 O75312,P25054,Q9UPP1,Q6ZWJ1,Q9UKG1,Q9NPI1,Q9UL46,P42575,P61289,Q8N7H5,Q6Y7W6,Q96DY7,Q07666,P31749,Q96HY6,P49321 16 +Positive regulation of nucleobase containing compound metabolic process 0.257011099625901 0.0371374328483965 0.970375425506361 1.0 1.0 439 P18615,Q8IXJ6,Q96EB6,Q92905,Q86V81,Q5VTR2,P98179,Q14011,Q9H1E3,Q92841,Q7Z4V5,P38159,Q96PK6,Q96HY6,Q9NPJ6,P51812,P23246,Q15418,P35637,Q9H7Z7,Q92804,Q9UER7,P09874,O75312,Q9UPP1,O95453,Q15427,P05067,Q14191,P05771,P53999,P16104,Q96HR8,Q96B01,Q8N163,Q9ULX6,Q03164,P50750,P38398,P19338,P12956,Q86U70,P51858,Q96L73,Q969T7,P22626,Q99729,O00165,P62995,P31749,P37198,Q96E39,Q92830,Q92945,O96028,O60869,Q96I24,Q5RKV6,P61978,O60506,Q9H7B4,Q9Y5A9,Q8NCF5,Q13595,P41440,P82970,Q9NY61,Q01804,Q6Y7W6,O00233,Q969G3,Q9NPI1,Q9H2V7,Q8IZL8,Q9NYF8,Q9Y2W1,P04150,Q13501,Q13148,P61457,Q9BRT9,Q9HB09,P67809,Q9BVS4,Q8N7H5,O95619,Q86VM9,Q6PL18,Q13546,Q96JB5,Q96EP5 91 +Hormone transport 0.2404343664126977 0.0370755853804147 0.970424738685006 1.0 1.0 38 O00233,Q6ZWJ1,Q8N183,P53985,Q6WKZ4,P00367 6 +Regulation of extrinsic apoptotic signaling pathway 0.239706657186931 0.036624910732562 0.9707840809598218 1.0 1.0 40 P02545,Q13546,Q9HB09,P38398,P61289,Q8IWB1,Q9NQX7,P30154,P31749,P09601 10 +Sphingomyelin biosynthetic process 0.3334293118341414 0.0359726494207959 0.9713041674346444 1.0 1.0 4 O15269,O15270,P22059 3 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.2635952211035868 0.0352393780159817 0.971888862602016 1.0 1.0 11 Q07021,Q86UT6,Q9Y4E8 3 +Positive regulation of cell development 0.2284369101600198 0.0349690008282071 0.9721044595036704 1.0 1.0 64 P55209,Q9UQB8,Q8IXJ6,P30536,P46108 5 +Positive regulation of rna binding 0.3055400946288416 0.0346127714412353 0.9723885174654106 1.0 1.0 6 P50750 1 +Amyloid beta clearance 0.2757467620709763 0.0341932960549143 0.9727230123898922 1.0 1.0 9 Q16850,P04035 2 +Female meiosis chromosome segregation 0.3978123200920936 0.0338661302505957 0.9729839018313022 1.0 1.0 3 Q15003,P33981 2 +Leukocyte cell cell adhesion 0.2346950204621083 0.0330487052158766 0.9736357476881264 1.0 1.0 46 P30825,P00813,P31749,P49366 4 +Dendrite self avoidance 0.3963730569948083 0.0327646781763422 0.9738622458120691 1.0 1.0 3 Q9Y639,P35613 2 +Negative regulation of proteasomal protein catabolic process 0.2468733880929236 0.0322694876434587 0.974257141859906 1.0 1.0 24 O43765,P46379,Q8N163,Q96HY6,Q9UL15 5 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.3952216465169671 0.0318981551730472 0.974553269851171 1.0 1.0 3 O60678,Q86X55 2 +Positive regulation of biomineralization 0.3296861503023303 0.0315223002069688 0.9748530079869292 1.0 1.0 4 P04920,Q4KMQ2,P20248 3 +Nuclear transcribed mrna catabolic process exonucleolytic 0.2551153456175742 0.0298048477010871 0.9762226925794052 1.0 1.0 15 Q969T7 1 +Lysosomal transport 0.2334753507564445 0.0291151969711902 0.9767727155059456 1.0 1.0 49 Q96ED9,Q9Y2T2,Q99816,Q9UNK0,Q99523,O14976,Q14108,Q8IWJ2,Q9H444,P11717,O00189,O14964,O15118,Q9P253,Q9HD42,Q9Y3E7,P46934 17 +Negative regulation of adenylate cyclase activity 0.3903281519861722 0.0283582537913232 0.9773764194475192 1.0 1.0 3 P08754,Q99996 2 +Negative regulation of lyase activity 0.3903281519861722 0.0283582537913232 0.9773764194475192 1.0 1.0 3 P08754,Q99996 2 +Rna destabilization 0.2334537512051065 0.0281117442354858 0.9775730272307396 1.0 1.0 50 O60506,P67809,Q9Y5A9,Q6Y7W6,Q13148,Q969T7,Q92945 7 +Regulation of synaptic transmission glutamatergic 0.3897524467472483 0.0279567729522325 0.9776966278452712 1.0 1.0 3 Q00535,Q8NBU5 2 +Skeletal muscle acetylcholine gated channel clustering 0.3129282071282834 0.0268688684032425 0.978564323963858 1.0 1.0 5 Q96EY1 1 +Fc receptor mediated stimulatory signaling pathway 0.2726247766268656 0.0268300841618477 0.978595258159114 1.0 1.0 9 Q9UJ41,Q9UKG1 2 +Epithelial cell differentiation involved in prostate gland development 0.3880253310305033 0.0267709380095845 0.9786424330157056 1.0 1.0 3 Q9NZJ7,P07602 2 +Metanephros morphogenesis 0.3880253310305021 0.0267709380095833 0.9786424330157064 1.0 1.0 3 P80723,P42224 2 +Negative regulation of epithelial cell differentiation 0.3880253310304952 0.0267709380095786 0.9786424330157102 1.0 1.0 3 P42224,Q13247 2 +Regulation of erad pathway 0.2890630795219171 0.0260823270424864 0.9791916732448168 1.0 1.0 7 O43765 1 +Meiosis ii cell cycle process 0.3499280575539519 0.0250798243894773 0.9799912929254008 1.0 1.0 2 O60566 1 +Meiotic sister chromatid cohesion centromeric 0.3499280575539519 0.0250798243894773 0.9799912929254008 1.0 1.0 2 O60566 1 +Negative regulation of neuron projection development 0.2475412662234417 0.0249610209162012 0.9800860547163376 1.0 1.0 22 P08670,O14976,Q9NR77,Q9NQX7,Q96G23,Q9UL15 6 +Sensory perception of light stimulus 0.2539790556774863 0.0248336496368584 0.9801876508001128 1.0 1.0 17 Q13432 1 +Camera type eye development 0.2387390555481055 0.0247438866859613 0.9802592492713392 1.0 1.0 35 Q04721,Q99797,P08670,P48681,P28289,P42575,Q15293,O94788,P54802 9 +Regulation of mammary gland epithelial cell proliferation 0.3842832469775349 0.0242960073287486 0.9806164978825344 1.0 1.0 3 Q07812,Q9NQC3 2 +Regulation of morphogenesis of an epithelium 0.3842832469775261 0.024296007328743 0.9806164978825388 1.0 1.0 3 P35222,P35453 2 +Chorio allantoic fusion 0.3389928057553907 0.0219555887133485 0.9824833820616644 1.0 1.0 2 O75190 1 +Regulation of dna dependent dna replication initiation 0.3198963432191185 0.0208395862264559 0.983373619345682 1.0 1.0 4 O60934,O95251,Q9ULV3 3 +Positive regulation of dna templated transcription elongation 0.2524430690611731 0.0206897929570325 0.9834931113189618 1.0 1.0 18 O60885,P50750,Q96FV9,Q9NYV4,O00267,Q9UPN6,Q86V81,Q13769 8 +Threonine catabolic process 0.3289208633093474 0.0196452622050067 0.9843263567715684 1.0 1.0 2 O75600 1 +Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process 0.3175928591995346 0.018521869984114 0.9852225308329184 1.0 1.0 4 O75116,P49755,P07948 3 +Regulation of aspartic type peptidase activity 0.3175928591995346 0.018521869984114 0.9852225308329184 1.0 1.0 4 O75116,P49755,P07948 3 +Maintenance of protein location 0.2375447593343871 0.0183062458414097 0.9853945448414704 1.0 1.0 34 P30536,P31749 2 +Positive regulation of coagulation 0.3191366906474769 0.01784624610334 0.9857615115690052 1.0 1.0 2 Q4KMQ2 1 +Negative regulation of cell growth 0.2424145221874964 0.0174418660988348 0.9860841099107084 1.0 1.0 30 O75489,Q8N163,Q8N0X7,Q9P0J0,Q96EB6,P50897,O14681 7 +Regulation of dna primase activity 0.3059908320277557 0.0170566850362118 0.9863913942140864 1.0 1.0 5 Q9BRT9 1 +Dna catabolic process exonucleolytic 0.3133812949640234 0.0169658609505906 0.9864638508650928 1.0 1.0 2 Q9H0D6 1 +Protein transport along microtubule 0.2958801498127419 0.0167714471002193 0.9866189486062495 1.0 1.0 6 P78559,Q9UPN4,O95817,P04792,P33176 5 +Negative regulation of platelet derived growth factor receptor signaling pathway 0.3082014388489155 0.0162731312636615 0.9870164928488124 1.0 1.0 2 O14964 1 +Positive regulation of translational initiation 0.249703288606657 0.0157338750557888 0.9874467019517704 1.0 1.0 14 Q86U44,Q9Y5A9,Q7Z739,Q13217,Q07666,Q9BYJ9 6 +Regulation of mitotic centrosome separation 0.3693149107656753 0.0156224589214376 0.9875355882401328 1.0 1.0 3 P43487,Q9UNZ2 2 +Myoblast migration 0.2984172661870449 0.0151908953575469 0.987879885277516 1.0 1.0 2 Q13464 1 +Positive regulation of protein phosphorylation 0.2251552717224683 0.0148329035661461 0.9881654892159896 1.0 1.0 120 P51116,Q9H7B4,P50750,P12956,Q96JM3,Q9NYB0,Q13501,Q8NDZ4,Q96EB6,O95429,P41440,O00165,P33981,Q9Y5X1,Q96A49,Q9ULW0,P31749,Q15058,Q96HY6,P31751,Q9NQS7,Q06787,Q9BZF1,Q99627,Q7KZI7,Q9UER7,Q13432,P51114,P18031,Q13546,P0DP25,P14174,Q9HAW4,Q86Y37,P05067 35 +Metal ion transport 0.2295196049345351 0.0144572424141446 0.9884651913060024 1.0 1.0 107 P21796,O15173,P0DP25,Q15043,P30536,Q9HD20,Q9Y5Y0,Q8NEW0,O75844,P31749,P46934,P05771 12 +Germ cell proliferation 0.2897841726618649 0.0144461016445079 0.988474079425897 1.0 1.0 2 Q13162 1 +Negative regulation of receptor binding 0.2817266187050305 0.0138981139470477 0.988911266437328 1.0 1.0 2 P16615 1 +Negative regulation of cell cycle 0.2297743103461278 0.0130129888923326 0.989617430100798 1.0 1.0 105 P43246,Q96K76,P16104,Q8N163,Q7Z5K2,P38398,Q13123,P49454,Q96FV9,Q9NZJ0,Q96EB6,P25054,Q9Y619,Q08J23,Q53EL6,Q9BXW9,P33981,P12270,O43464,Q96PK6,Q6NUQ1,Q12888,Q96EA4,Q96DY7,Q6Y7W6,Q92830,Q96JB5,Q9NPI1,Q96RU2,P42575,O75663,Q9HAW4,O60566,Q96BK5 34 +Prostate gland growth 0.3601036269429948 0.0111868883770214 0.9910743406500668 1.0 1.0 3 Q9NZJ7,P07602 2 +Extracellular exosome assembly 0.3589522164651589 0.0106771339245883 0.9914810415501524 1.0 1.0 3 O00560,Q99816 2 +Positive regulation of chromosome condensation 0.3006912442396418 0.0101232269238947 0.9919229714874308 1.0 1.0 5 Q9NTJ3,Q9BPX3,O95347,Q15003 4 +Positive regulation of cell cycle g1 s phase transition 0.2440389237887294 0.0099860248461965 0.992032437373456 1.0 1.0 22 P31749,Q96HY6,Q8N7H5,Q6ZWJ1 4 +Negative regulation of protein targeting to mitochondrion 0.3560132144470541 0.0094190594207735 0.9924847890343108 1.0 1.0 3 O95429 1 +Glycerol ether metabolic process 0.2798926225618841 0.0087263718991212 0.993037450955828 1.0 1.0 7 O15228 1 +Negative regulation of cytokine production 0.2398134768377003 0.0080680405288357 0.9935627048636262 1.0 1.0 31 P30536,Q53EL6,Q07021,O43823,P09601 5 +Dna dependent dna replication maintenance of fidelity 0.2484710708263142 0.0077807860567862 0.9937918935748906 1.0 1.0 16 Q9NVH0,P50750,Q9H1E3,Q9Y3Z3,Q14191,Q86V81 6 +Negative regulation of blood circulation 0.3494530800230178 0.0068261688126719 0.9945535475926444 1.0 1.0 3 P16615,P05023 2 +Positive regulation of membrane protein ectodomain proteolysis 0.348405806888768 0.0064387315862959 0.9948626709727666 1.0 1.0 3 O43847 1 +Mitotic intra s dna damage checkpoint signaling 0.3025699967228674 0.0051409563902495 0.9958981283368238 1.0 1.0 4 Q9BXW9 1 +Snorna localization 0.3020443420673704 0.0047250732173226 0.9962299510597916 1.0 1.0 4 Q9NWS0,P22087,Q8WWY3 3 +Necrotic cell death 0.2471859169890835 0.0044841333744788 0.9964221912020296 1.0 1.0 19 P30536,Q13546 2 +Response to lectin 0.3014684710624759 0.0042733623980362 0.9965903604974882 1.0 1.0 4 Q92793,P07948,Q13177 3 +Innate immune response activating signal transduction 0.3014684710624759 0.0042733623980362 0.9965903604974882 1.0 1.0 4 Q92793,P07948,Q13177 3 +Regulation of helicase activity 0.2616466546332961 0.0030571820926502 0.997560725408436 1.0 1.0 9 Q96EB6,Q04837 2 +Presynaptic endocytosis 0.2417182030478691 0.0028824961913788 0.9977001039772162 1.0 1.0 12 Q13464,O14976,P0DP25 3 +Negative regulation of histone h4 acetylation 0.3370427457232925 0.0026716037333795 0.9978683711642916 1.0 1.0 3 Q96EB6 1 +Cellular response to external stimulus 0.2299196628651693 0.0021867463488327 0.9982552302404152 1.0 1.0 55 Q9P289,Q13573,Q99439,Q8NEZ5,P09651,P22681,P21964,P11166,P42575,O95831,Q96EB6,Q9H773,Q14191,P07948,P09601 15 +Regulation of jun kinase activity 0.2869768459924269 0.0020340495071116 0.9983770644214778 1.0 1.0 6 Q53EL6 1 +Regulation of calcium ion dependent exocytosis 0.2983011805355548 0.0018610631802202 0.9985150872790034 1.0 1.0 4 P04899,P16615,Q00535 3 +Threonine metabolic process 0.3290155440414388 0.0004543156704072 0.9996375085533212 1.0 1.0 3 O75600,O43175 2 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.2959976965159791 0.0001820618849422 0.9998547356336964 1.0 1.0 4 Q9Y6G9,P12270,O14777 3 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fc0a114b3865fc44d7efd396d3a821e7885e30e5 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosomal vesicle exocytosis", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in prostate gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex gabaergic interneuron development", "Cerebral cortex gabaergic interneuron differentiation", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule exocytosis", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Direct ossification", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial cilium movement involved in determination of left right asymmetry", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Gabaergic neuron differentiation", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindgut development", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Induction of positive chemotaxis", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isg15 protein conjugation", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesendoderm development", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motile cilium assembly", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of torc1 signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast development", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell differentiation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion mediated by integrin", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix constituent secretion", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic dense core vesicle exocytosis", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prostate gland morphogenesis", "Prostate glandular acinus development", "Prostate glandular acinus morphogenesis", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to site of double strand break", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adiponectin secretion", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen processing and presentation", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone development", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in prostate gland morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell differentiation", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix constituent secretion", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of inflammatory response to wounding", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron maturation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of positive chemotaxis", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of cardiac muscle", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of store operated calcium entry", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm flagellum assembly", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Strand invasion", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell antigen processing and presentation", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APC", "APEH", "APEX1", "APEX2", "API5", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC8", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD5", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRIX1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf29", "C12orf57", "C12orf73", "C19orf70", "C1QBP", "C21orf59", "C2CD5", "C2orf49", "C3orf38", "C3orf58", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC94", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CENPE", "CENPF", "CENPI", "CENPK", "CENPU", "CENPV", "CEP131", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG5", "COG7", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSN1", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC8", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM118B", "FAM120B", "FAM126A", "FAM129B", "FAM162A", "FAM192A", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXL18", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLVCR1", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSD1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAUS7", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGN5", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HOOK2", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JCAD", "JUP", "KARS", "KAT2A", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT1", "LCOR", "LDAH", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRFIP1", "LRSAM1", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "LYSMD3", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP4K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED17", "MED23", "MED24", "MED4", "MEN1", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MMS22L", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUT", "MVD", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA20", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND4", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKBIE", "NFS1", "NGDN", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OFD1", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBK", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDCD11", "PDCD2L", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTAR1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RFX1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSRP1", "ST7", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD9", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAOK2", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGS1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TROVE2", "TRRAP", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTK", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TUT1", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL4A", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBL5", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS11", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VRK1", "VRK3", "VTA1", "WAPL", "WARS", "WARS2", "WASHC4", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR54", "WDR6", "WDR61", "WDR62", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP73", "WRN", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBED1", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF106", "ZNF148", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAK1", "AASDHPPT", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCC10", "ABHD10", "ABHD12", "ACBD5", "ACIN1", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL1", "ACSL3", "ADA", "ADD1", "ADD2", "ADD3", "ADI1", "ADK", "AFG3L2", "AGPS", "AIFM1", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKAP9", "AKT1", "AKT2", "ALDH1A2", "ALDH1B1", "ALDH6A1", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANO6", "ANP32A", "AP3M1", "AP4M1", "APC", "APOL2", "APP", "APPL1", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGEF2", "ARHGEF7", "ARMC1", "ARMCX3", "ASH2L", "ASNA1", "ATAD1", "ATAD2", "ATAD3A", "ATAD5", "ATF7IP", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5B", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "AUP1", "AURKA", "B3GALT6", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BASP1", "BAX", "BAZ1B", "BAZ2A", "BCAS2", "BCAS3", "BCL2L12", "BCL2L13", "BCLAF1", "BEND3", "BICD2", "BRCA1", "BRD4", "BRD7", "BRMS1L", "BSG", "BTAF1", "BUB1B", "C12orf73", "C19orf70", "C1QBP", "C3orf58", "CACUL1", "CALD1", "CALM3", "CANT1", "CAPZB", "CARM1", "CASK", "CASP2", "CAST", "CBL", "CBX5", "CCAR2", "CCDC134", "CCDC47", "CCNA2", "CCNB2", "CD2BP2", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CDC73", "CDCA2", "CDK12", "CDK2", "CDK5", "CDK5RAP3", "CDK9", "CENPF", "CENPK", "CEP131", "CEP44", "CERS1", "CERS2", "CETN2", "CHAC2", "CHAMP1", "CHCHD3", "CHERP", "CHKA", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHRAC1", "CHST14", "CHUK", "CIRBP", "CIZ1", "CLASP1", "CLASP2", "CLCN3", "CLINT1", "CLK3", "CLN5", "CLPB", "CLPP", "CLPTM1", "CLSPN", "CLUH", "CNN2", "COA3", "COIL", "COMT", "COPS5", "COPS8", "COQ6", "COX4I1", "COX7A2", "CPD", "CPOX", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREBBP", "CRK", "CRTAP", "CSGALNACT2", "CSNK2B", "CSTF2", "CTBP2", "CTNNB1", "CUTA", "CWC15", "CYB5B", "CYB5D2", "CYP51A1", "DAGLB", "DAXX", "DAZAP1", "DCAF15", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D4", "DDRGK1", "DDX17", "DDX3X", "DERL2", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHX36", "DHX8", "DHX9", "DIABLO", "DICER1", "DNAJA3", "DNAJB6", "DNAJC1", "DNAJC3", "DNAJC9", "DNM1L", "DOCK7", "DOHH", "DTL", "DYNC1LI1", "ECE1", "ECH1", "ECI2", "EDF1", "EHMT2", "EI24", "EIF4E2", "EIF5", "ELAVL1", "EMC2", "EMD", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "ERAP1", "ERBIN", "ERCC4", "ERCC6L", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ESPL1", "ESS2", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC1", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC6", "EXOSC8", "EXOSC9", "EZR", "FAM118B", "FAM208A", "FAM49B", "FAM50A", "FAM98B", "FANCD2", "FASTKD1", "FBL", "FBXO22", "FDFT1", "FECH", "FGFR1OP", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLVCR1", "FMR1", "FNTA", "FNTB", "FTO", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "GAK", "GAPVD1", "GBA", "GCAT", "GCC2", "GCLC", "GDE1", "GGCX", "GGPS1", "GIGYF2", "GINS2", "GINS4", "GLB1", "GLG1", "GLMN", "GLUD1", "GNA13", "GNAI2", "GNAI3", "GNL3L", "GNPAT", "GOLGA2", "GOLGA5", "GOLGB1", "GOLPH3", "GPAM", "GPAT4", "GPKOW", "GRSF1", "GSDME", "GSTM3", "GTF2B", "GTF2F1", "H2AFX", "HAUS1", "HAUS4", "HAX1", "HCCS", "HDAC1", "HDGF", "HDGFL2", "HDGFL3", "HEATR3", "HEBP1", "HEXA", "HGS", "HLA-A", "HLA-C", "HM13", "HMCES", "HMGB1", "HMGCR", "HMGN5", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HOXD13", "HSD17B12", "HSPB1", "HSPD1", "HTRA2", "ICMT", "IDH2", "IGBP1", "IGF2R", "IK", "IKBIP", "ILK", "ILVBL", "IMMT", "INA", "INCENP", "INTS13", "IQCB1", "ITCH", "ITGB1", "ITM2C", "ITPRIP", "IWS1", "JCAD", "KAT2A", "KAT7", "KDELR1", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF14", "KIF18B", "KIF20A", "KIF23", "KIF4A", "KIF5B", "KIFAP3", "KLC1", "KLC2", "KMT2A", "KNL1", "KPNA2", "L2HGDH", "LARP1", "LARP4", "LARP7", "LARS", "LCLAT1", "LCOR", "LDAH", "LDB1", "LEMD3", "LGALS3BP", "LGMN", "LIMA1", "LMNA", "LMNB1", "LNPEP", "LRSAM1", "LSM3", "LSM6", "LSS", "LTA4H", "LTV1", "LYN", "LYPLA1", "MAIP1", "MAP1A", "MAPK1", "MAPRE1", "MAPRE2", "MARK2", "MATR3", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCL1", "MCM3AP", "MCM4", "MCM6", "MECP2", "MED4", "METTL3", "MFAP1", "MFN1", "MFSD10", "MFSD3", "MGEA5", "MIA2", "MIA3", "MICU1", "MICU2", "MIEF1", "MIF", "MIPEP", "MMGT1", "MORC2", "MORF4L1", "MOSPD2", "MPHOSPH10", "MPHOSPH8", "MPP1", "MPV17L2", "MSH2", "MSI2", "MTAP", "MTBP", "MTCH1", "MTDH", "MTFP1", "MTMR14", "MTMR2", "MTMR4", "MTOR", "MTX1", "MTX2", "MYEF2", "MYH14", "NAA35", "NAA40", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NASP", "NAT10", "NBAS", "NBN", "NCAPG", "NCAPH", "NCBP3", "NCL", "NCOA5", "NCOR1", "NDC1", "NDC80", "NDUFA13", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB8", "NDUFS3", "NECAP2", "NEDD4", "NEDD4L", "NEFM", "NELFCD", "NELFE", "NENF", "NES", "NFATC2IP", "NIPBL", "NLN", "NLRX1", "NNT", "NOL8", "NOLC1", "NONO", "NOTCH2", "NPC1", "NPEPPS", "NPM1", "NPTN", "NR3C1", "NRDC", "NSD1", "NSD2", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3B", "NUCB2", "NUCKS1", "NUDT12", "NUDT21", "NUMA1", "NUP107", "NUP153", "NUP214", "NUP37", "NUP54", "NUP58", "NUP62", "NUP88", "NUP93", "NUP98", "NUPL2", "OCIAD1", "OCLN", "OPA1", "OSBP", "OSBPL3", "OSBPL6", "OSBPL8", "OTUD4", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPN1", "PAF1", "PAK2", "PARN", "PARP1", "PARP2", "PAWR", "PCBD1", "PCM1", "PCYOX1", "PDCD4", "PDCD5", "PDCL3", "PDHX", "PDK1", "PDK3", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PECR", "PEF1", "PELO", "PELP1", "PEX14", "PEX19", "PEX3", "PFDN2", "PFDN5", "PFDN6", "PGAM5", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PIH1D1", "PIK3C2A", "PINX1", "PIP4K2C", "PISD", "PITRM1", "PLA2G15", "PLAA", "PLBD2", "PLIN3", "PLK1", "PLOD3", "PMPCA", "PNPLA2", "PNPLA6", "POLDIP2", "POLR1C", "POLR1E", "POLR3B", "PON2", "POR", "PPHLN1", "PPIL4", "PPME1", "PPP2R1B", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX4", "PREPL", "PRKCB", "PRKCD", "PRMT3", "PRMT9", "PRPF31", "PRPF39", "PRPF40A", "PSAP", "PSIP1", "PSMB4", "PSMD11", "PSMD9", "PSME1", "PSME2", "PSME3", "PSMF1", "PSPC1", "PTAR1", "PTGES2", "PTPA", "PTPN1", "PTRH2", "PUF60", "PUM1", "PURA", "PXMP2", "QKI", "RAB11FIP1", "RAB18", "RAB1B", "RAB24", "RAB3B", "RAB6A", "RABGEF1", "RABGGTA", "RACGAP1", "RAD18", "RAD50", "RAD51AP1", "RANBP1", "RANBP2", "RANBP3", "RAPGEF2", "RAVER1", "RB1", "RBM10", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM3", "RBM4", "RBM5", "RBM6", "RBMX", "RBMXL1", "RBPJ", "RCN1", "RDX", "RECQL4", "REPS1", "RETSAT", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMND1", "RNF20", "RNF219", "RNF31", "RNF40", "ROCK1", "ROCK2", "RPRD1B", "RPS6KA1", "RPS6KA3", "RPUSD2", "RRP8", "RSF1", "RTN4", "RUFY1", "SAAL1", "SAFB", "SAMHD1", "SAMM50", "SARNP", "SART1", "SART3", "SC5D", "SCAF11", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDCCAG3", "SDF4", "SEC11A", "SEC16A", "SEC63", "SEH1L", "SERBP1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B4", "SF3B6", "SFPQ", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SHCBP1", "SIGMAR1", "SIRT1", "SIRT2", "SIRT3", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35F2", "SLC39A14", "SLC4A2", "SLC6A15", "SLC7A1", "SLIT2", "SLU7", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCE1", "SMC2", "SMC4", "SMC5", "SMC6", "SMG5", "SMN1*", "SMNDC1", 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1.4271844660194175 4.439320388349515 0.5256630412856145 0.4795278875555782 1.093688350806908 0.8638969757615467 0.9368809323777078 0.3221784257132529 0.0327528823448254 0.0683810764565047 0.1349531130589082 0.0498779046475234 0.1641299211995837 +Tim23 mitochondrial import inner membrane translocase complex 1 6 2.2132423553544176 0.0268809414344597 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.018040118168484 0.0011617774889038 0.0047533286028597 0.027832231049335 0.0974859568290139 +Ciliary transition zone 4 11 2.125909617335579 0.0335107859524221 1.9635922330097089 6.907766990291262 0.9295898692526422 0.3532985326295446 1.5457849700174688 1.7711928579014855 0.854807445224746 0.2896111184937897 0.2640644032404496 0.2180755491779121 0.0890100643743446 0.3601862036851755 0.1079287008920704 +Intrinsic component of organelle membrane 37 141 2.1108692076254054 0.0347835554426798 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 0.2230937725435725 0.0525029693113603 0.1634987855413628 0.1950974559362049 0.0621964035344577 +Proton transporting atp synthase complex 2 11 2.0751645703602226 0.0379712850138986 4.157766990291262 11.08495145631068 0.5328143574617974 0.3012358599713604 2.3610641964760792 1.138499586439592 1.3748267965121657 0.2836171984539964 0.2812476453561096 0.0771453392642774 0.1515272625734178 0.3411306657380243 0.0470360579614364 +Apical plasma membrane 9 49 2.012407025091254 0.0441770485631138 13.313106796116504 44.91504854368932 0.8056122914935105 0.4638533528605782 6.08368206230376 5.803837594461636 1.1490032654706197 0.3657186109722784 0.1881180963572018 0.1702233046299462 0.194273291085049 0.0893390496573199 0.241918141705748 +Haus complex 1 6 1.9988631887958948 0.0456231585963398 1.7142857142857142 4.192118226600985 0.9491182117305148 0.3338762298151981 1.141316695812668 1.4443833619809177 1.0587020246145291 0.3035334299176759 0.0095386982765907 1.0 1.0 0.0148625463558957 0.0546176715347421 +Receptor complex 7 23 1.9804528065313087 0.0476526712992249 4.546116504854369 19.37135922330097 -1.0257716368983243 0.3014359024485322 2.884560417457156 4.82966712727482 1.2452382063769163 0.3057220790362489 0.7751984084114432 1.0 0.7583477142273662 0.8729930918911721 0.930422457877538 +Mitochondrial envelope 57 329 1.9791777334774687 0.047795998960473 98.51456310679612 309.05582524271847 1.3784407074331837 0.4315621435689855 37.853540978552445 29.592036616547553 2.6690149272426917 0.4358105924461398 4.964043267301617e-07 2.856109651745165e-05 8.582542643035936e-06 1.637377496719574e-06 1.0956015917986809e-07 +Golgi cisterna 10 27 1.964486051486536 0.0494737522956816 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 0.7587773478168369 0.2922756805728106 0.5071521873221705 0.8341449762925521 0.0642903416117007 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cebe64b4b66c6630fa85b7252864710e28909a62 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 909, + "title": "Average number of proteins per term", + "value": 31.12981298129813 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..255032ed3e96054003333fe326c74804ac1263b3 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0eb950efcd5a8d39449ae8f3f199cbeb285e6c44 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,259 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Intrinsic component of mitochondrial membrane 0.5203184814505086 3.1142001547295597 0.001844443214346 0.8132803493514531 0.0825645551142365 48 Q99595,Q15070,O60830,Q16134,Q5XKP0,O75431,Q9NX63,Q16891,Q9Y3D6,Q9Y512,Q9Y2R0,Q13505,Q8IWA4,Q9H9P8,Q96NB2,O14925 16 +Intrinsic component of mitochondrial inner membrane 0.5825420049864609 3.0618661912264225 0.0021996175745715 0.8648884601504319 0.0825645551142365 33 Q99595,Q15070,O60830,Q16134,Q5XKP0,O75431,Q9NX63,Q16891,Q9Y512,Q9Y2R0,Q13505,Q9H9P8,Q96NB2,O14925 14 +Nuclear inner membrane 0.6391459263103245 2.9524854168651724 0.0031522695938022 0.9432976062603918 0.0988073469229729 23 P20700,Q9H1E5,Q9UH99,Q99720,Q9Y2U8,Q03252,P62995,P43243,O75844,Q14728 10 +Intrinsic component of plasma membrane 0.4338054895348181 2.919104707498309 0.0035103829078078 0.9590970017635584 0.1063646021065766 88 P04439,Q8WTV0,O00400,P41440,Q99808,O15118,Q9UJS0,Q04721,O96005,Q9NR28,Q99805,Q15043,P30825,P10321,Q9UIQ6,Q9BTU6,P36551,P0DP25,P53985,Q9H1Z9,P33527,P05067,O00264 23 +Nuclear membrane 0.3891407686851679 2.7439240267192613 0.006070958636325 0.9960550571248744 0.1557294435718647 119 Q96PE3,Q9BZF3,Q99523,Q15154,O60318,O75608,Q9NZJ0,Q96EB6,P20700,Q5BJF2,Q9H1E5,O76062,P50402,P02545,P49790,O00165,P49792,P62995,Q9H8M7,Q9H4L5,P12270,Q12765,Q86UE4,P37198,Q5SNT2,Q14728,Q5UIP0,Q9UIS9,P67809,Q9BVL2,Q9BZF1,Q96KC8,Q9Y2U8,O15504,Q9NUL3,Q6NUM9,P43243,O95619,Q86WB0,Q8N1F7,O14681,Q96RT1,Q9BTX1,Q13185,Q9UPP1,Q9BVI4,Q99720,Q9H2V7,P57740,Q96T37,Q5XPI4,Q9Y3D9,Q03252,Q7Z3B4,Q8IWB1,Q9UH99,O75844,P52948,Q15007 59 +Organelle inner membrane 0.3817214338714473 2.7297195642273415 0.0063388222355984 0.9969123008211842 0.1557294435718647 258 Q99595,O75964,O60830,O43676,P06576,P22830,P00846,Q16134,Q9P0J0,Q9BQT8,Q9Y2R0,O95831,Q13505,P13073,Q567V2,Q9H9P8,Q9Y2Z9,P20700,Q10713,Q13423,Q9H1E5,Q9Y619,Q8N183,Q69YU5,P14927,P22695,P62995,Q9Y5Y0,Q14728,Q9H061,Q9UJS0,P23786,Q9Y2U8,P43243,P53701,Q8IYU8,O96000,Q9BSK2,Q96NB2,O43772,O75489,P36551,Q70HW3,Q16540,O95169,Q99720,Q9H2V7,P14406,Q9NX63,Q9UDX5,Q03252,Q9Y512,Q6DKK2,Q9UH99,O75844 55 +Microbody 0.4458227055214674 2.521494750693138 0.0116857419009503 0.9999771118704168 0.2470311485573003 56 P08670,Q13011,O75521,O15228,O75381,Q15067,P48735,P56589,O14734,Q5T8D3,Q9NR77,Q9BQG2,Q9Y3D6,Q9BY49,P40855,P34913,Q8N4Q0 17 +Spliceosomal complex 0.3443380055205507 2.3811698085873565 0.0172577545879608 0.9999998658410468 0.3137459784091284 134 O60506,Q07955,O75940,O43390,Q13123,Q9UBB9,P22626,Q13595,P98179,Q14011,O95391,P62310,P62995,P38159,P31942,O60508,Q96E39,P55081,Q01130,P52597,P52756,P51991,P31943,P61978 24 +Microbody membrane 0.5415199165393152 2.3515331094145333 0.0186962256447908 0.9999999645714354 0.323967743080326 26 O15228,O75381,Q15067,P56589,Q5T8D3,Q9NR77,Q9Y3D6,P40855,Q9BY49 9 +Organelle envelope lumen 0.4727006158563846 2.300829674988217 0.0214012603990114 0.9999999971184328 0.3297245034356173 39 Q96AY3,P36551,Q9NR28,O00165,Q9BYT8,O95831,Q8IYU8,P05067 8 +Envelope 0.3272626163392651 2.2792314905322537 0.0226533080867559 0.9999999991000458 0.3347229556701904 515 Q99595,Q96AY3,O60830,Q9BZF3,P22830,P00846,Q9NS69,Q9BQT8,O75608,Q86UT6,Q9Y2R0,O95831,Q96EB6,Q9Y2Z9,Q5BJF2,Q15070,P02545,Q69YU5,P30536,Q9HCL2,O15118,Q12765,O43169,Q14728,Q9NR28,Q9BVL2,Q3ZCQ8,P23786,P45880,O15504,P53701,O43615,Q96NB2,O14681,O43772,P09874,P45973,Q9UPP1,Q9Y5Z9,Q16540,O95169,Q99720,Q8N0X7,P14406,Q9UDX5,P57740,P42166,Q6DKK2,O75844,Q8WY22,P05067,P21796,Q9Y375,O43676,P35658,O60318,Q9UBX3,P20700,O14925,Q13423,Q9Y619,Q8N183,O00165,P14927,Q92667,P62995,Q9H4L5,Q9H8M7,Q9Y5Y0,Q9HD42,Q92575,Q8IWA4,Q86UE4,P37198,O15173,Q5XKP0,O75431,Q9NVT9,P09601,Q9NQG6,Q86WB0,Q16891,P18031,Q9BVI4,Q70HW3,P0DP25,Q9NX63,Q6P4A7,P82663,Q5XPI4,O75947,Q9UH99,Q14318,P82933,P52948,O00264,O75964,O60313,Q9P032,P06576,Q16134,Q13505,Q10713,Q8N2G8,Q9H1E5,Q9BXK5,Q9H444,P22695,Q9H061,Q9UJS0,Q9Y3D6,Q8N4H5,Q6NUM9,Q8IYU8,Q9BSK2,Q8N1F7,P36551,Q9H2V7,P41208,Q8IWB1,Q15007,Q99523,O15228,Q15154,Q9P0J0,Q9BYT8,P13073,Q567V2,Q9H9P8,P07437,Q9NQZ5,Q8NFH4,P67809,Q99567,Q9Y2U8,Q9Y277,P43243,O96000,O95619,Q9BTX1,O75489,Q9H6Z4,P80303,Q03252,Q9Y512,Q9NQ50 146 +Golgi lumen 0.8217884367126904 2.244363830303595 0.0248090017186903 0.9999999998790732 0.3347229556701904 6 P05067 1 +Endoplasmic reticulum lumen 0.4191918031924949 2.2419329796001843 0.0249657041735873 0.9999999998955084 0.3347229556701904 57 Q96AY3,O43852,Q14257,Q02818,Q9Y680,O43681,O15460,Q9NWM8,P13674,P05067,Q9NZ08 11 +Glial cell projection 0.8698320914791459 2.2282534031200343 0.0258636217208831 0.9999999999547764 0.3347229556701904 5 Q8IXJ6 1 +Tim23 mitochondrial import inner membrane translocase complex 0.8148092594234123 2.2132423553544176 0.0268809414344597 0.9999999999825064 0.3347229556701904 6 Q99595 1 +Ciliary transition zone 0.6555775256855136 2.125909617335579 0.0335107859524221 0.999999999999965 0.3855884377731218 11 Q15051,Q92845,A6NIH7,P41208 4 +Intrinsic component of organelle membrane 0.3240490229234655 2.1108692076254054 0.0347835554426798 0.9999999999999896 0.3855884377731218 141 Q99595,O60830,Q8TCT8,P42892,Q16134,P04439,Q86XL3,Q9Y2R0,Q13505,Q9H9P8,O14925,Q15070,O15118,Q8TCT9,Q8IWA4,Q9Y679,Q5XKP0,O75431,P10321,Q9Y2U8,Q9Y3D6,P98194,Q8N4V1,Q96NB2,Q16891,Q15006,Q9Y5Z9,Q8N6G5,P56589,Q9NX63,Q6P4A7,Q9Y512,Q15629,Q9UH99,O75844,Q9Y282,Q14318 37 +Proton transporting atp synthase complex 0.6464710717952155 2.0751645703602226 0.0379712850138986 0.9999999999999994 0.4158541937064325 11 O75964,P00846 2 +Myofilament 0.8828102505038887 2.027177116521969 0.0426443025268072 1.0 0.4412850235590167 4 P67936,Q9NYL9,P28289 3 +Striated muscle thin filament 0.8828102505038887 2.027177116521969 0.0426443025268072 1.0 0.4412850235590167 4 P67936,Q9NYL9,P28289 3 +Apical plasma membrane 0.4137641234272203 2.012407025091254 0.0441770485631138 1.0 0.4412850235590167 49 P08183,P41440,Q99808,Q15043,O00165,P30825,Q16625,P53985,P33527 9 +Haus complex 0.7673636360519169 1.9988631887958948 0.0456231585963398 1.0 0.4507766430877488 6 Q96CS2 1 +Receptor complex 0.5070168988130842 1.9804528065313092 0.0476526712992249 1.0 0.4542589983512586 23 Q04721,Q13546,Q9NR28,Q96EP0,O43464,P05067,P07948 7 +Mitochondrial envelope 0.3476321282238561 1.9791777334774692 0.047795998960473 1.0 0.4542589983512586 329 Q99595,Q96AY3,P21796,O60830,O43676,O75964,P06576,P22830,P00846,Q16134,O15228,Q9NS69,Q9P0J0,Q9BQT8,Q9BYT8,Q9Y2R0,O95831,Q13505,P13073,Q567V2,Q9Y2Z9,Q10713,Q13423,Q9Y619,Q8N183,Q69YU5,P30536,O00165,P14927,Q9BXK5,P22695,Q9Y5Y0,O43169,Q9H061,Q9UJS0,Q9NR28,P23786,P45880,Q9Y3D6,Q8N4H5,P09601,P53701,Q8IYU8,Q9BSK2,Q96NB2,O43772,P36551,Q70HW3,Q16540,O95169,P0DP25,Q9H2V7,P14406,Q9NX63,Q9UDX5,Q6DKK2,O00264 57 +Golgi cisterna 0.4883899668438505 1.964486051486536 0.0494737522956816 1.0 0.4542589983512586 27 Q15363,Q8WVQ1,Q99523,Q8N6G5,Q8NBZ7,Q08379,P98194,Q96L58,Q10713,Q8TBA6 10 +Endosome lumen 0.8048176738765107 1.9485636323006188 0.0513475587882388 1.0 0.4598777995874405 5 Q9UIQ6 1 +Nuclear inclusion body 0.6627805268164942 1.9289053425357312 0.0537426144715849 1.0 0.4609755297741323 9 P49790,Q86U42,P49792,P12270,Q9NS91,P52948 6 +Microbody lumen 0.5215136485916828 1.9235206517649217 0.0544146954455813 1.0 0.4609755297741323 21 O00116,Q13011,O75521,O15228,Q15067,O14734,Q9BQG2,P34913 8 +Inner mitochondrial membrane protein complex 0.3645004931376329 1.9168091883638747 0.0552621772158712 1.0 0.4609755297741323 79 Q99595,O75964,O75489,O60830,O43676,P06576,O95169,P00846,P14927,P13073,P14406,Q9NX63,Q9P0J0,P22695,Q13505,O96000,Q8IYU8 17 +Outer mitochondrial membrane protein complex 0.5630601032875466 1.897119920481971 0.0578121126449406 1.0 0.4609755297741323 16 Q5XKP0,O75431,Q9NX63,Q9NS69,Q9Y512,Q8N4H5,Q13505,Q8IWA4 8 +Perinuclear endoplasmic reticulum 0.7425929489155706 1.8850379301669056 0.05942471703466 1.0 0.4656643774526375 6 Q9BZF3 1 +Cajal body 0.4363000263424167 1.8343515357628468 0.0666018287353156 1.0 0.4843284985632151 34 Q15020,Q16637,O75940,Q06787,Q01844,O75312,Q659A1,Q14978,Q8WWY3,P38432,Q9H814,Q96RS0,P22626,Q9BPY3 14 +Golgi cisterna membrane 0.4971825572372328 1.81993420702478 0.0687690248767123 1.0 0.4922129418341063 22 Q15363,Q8WVQ1,Q99523,Q8N6G5,Q8NBZ7,Q08379,P98194,Q10713 8 +Intermediate filament 0.5254909373863423 1.8132311280434352 0.0697961806829441 1.0 0.4956619393812204 19 P08670,Q16352,P48681,Q03252,P07197,P20700 6 +Apical part of cell 0.3658698733388719 1.7896815400370345 0.073505121684348 1.0 0.4986280269483016 64 P08183,P36551,P41440,Q99808,Q15043,O00165,P30825,Q16625,P53985,P41208,P33527,P05067 12 +Brush border membrane 0.6324041170002404 1.7680611756838471 0.077050677057588 1.0 0.5075294597488952 9 Q14728,P41440,P40855 3 +Proton transporting two sector atpase complex 0.4727948838578416 1.7390886218533523 0.0820191757310579 1.0 0.5154136727875641 24 P56385,O75964,Q15904,P06576,P00846,Q93050,Q8N511,O75947,Q9Y5K8,O75787,P36543 11 +Compact myelin 0.9217266187050352 1.730995533605441 0.0834525610791492 1.0 0.5154136727875641 2 Q8IXJ6 1 +Paraspeckles 0.703972233187675 1.7051280925729535 0.0881705372833447 1.0 0.5322619588714355 6 Q8WXF1,P23246,P52272 3 +Proton transporting two sector atpase complex proton transporting domain 0.579388777118549 1.6932981828787177 0.0903987238438397 1.0 0.5322619588714355 11 O75964,P00846,Q93050,O75787 4 +Anaphase promoting complex 0.5387022839641193 1.5994640813358745 0.1097175234709899 1.0 0.5744740744085688 12 O60566,Q96DE5,Q9UJX3,Q9UJX2 4 +Cytoplasmic stress granule 0.3787282241734903 1.5937113949667394 0.1110006908303677 1.0 0.5744740744085688 47 Q13464,Q9Y5A9,Q13148,Q9Y520,O60828,Q14011,Q7Z739,Q71RC2,Q15717,P67809,Q06787,Q14671,Q9NUL3,Q6Y7W6,Q01085,Q99700,Q14157,Q7Z417,Q9BWF3,P61978,Q9BYJ9 21 +Messenger ribonucleoprotein complex 0.7186059907834169 1.5664265495765672 0.1172487914969213 1.0 0.5744740744085688 5 P51991,P67809,Q06787,Q99729 4 +Proton transporting atp synthase complex coupling factor f o 0.6439953139302593 1.562619716749463 0.1181420678937232 1.0 0.5744740744085688 7 P00846 1 +Plasma membrane signaling receptor complex 0.5568461764632402 1.5620787367045832 0.1182694413668632 1.0 0.5744740744085688 11 O43464,Q96EP0,Q9NR28 3 +Platelet alpha granule 0.5118049065920014 1.5611798548090203 0.1184813207827426 1.0 0.5744740744085688 16 Q9Y6I9,Q8NBX0 2 +Platelet alpha granule lumen 0.5556883209976857 1.5553051877851882 0.119873402416327 1.0 0.5744740744085688 11 Q9Y6I9,Q8NBX0 2 +Cation channel complex 0.5313748978739596 1.554450105851119 0.1200770892603169 1.0 0.5744740744085688 12 Q15257,P0DP25 2 +Synaptonemal structure 0.6034693413035568 1.541163460809725 0.1232770079267964 1.0 0.5806155451059997 8 Q92791,Q7Z5K2,P38398 3 +Photoreceptor connecting cilium 0.6657757307069754 1.5245842788271258 0.1273628210746626 1.0 0.5842546288353325 6 Q15051,Q92845 2 +Nuclear envelope 0.3091122330272647 1.5224110057991491 0.1279061288649408 1.0 0.5842546288353325 194 Q9BZF3,O75608,Q96EB6,Q5BJF2,P02545,O15118,Q12765,Q14728,Q9BVL2,O15504,O14681,P45973,P09874,Q9UPP1,Q99720,P57740,P42166,O75844,P05067,P35658,O60318,P20700,O00165,P62995,Q9H8M7,Q9H4L5,Q92575,Q9HD42,Q86UE4,P37198,O15173,Q86WB0,Q9BVI4,Q5XPI4,Q9UH99,P52948,Q8TD16,Q9NZJ0,Q8N2G8,Q9H1E5,P49790,Q9H444,P49792,Q9BZF1,Q96KC8,Q6NUM9,Q8N1F7,Q96RT1,P11717,Q9H2V7,Q9Y3D9,P41208,Q8IWB1,P49454,Q15007,Q99523,Q15154,Q9Y3E7,O76062,P50402,P07437,Q9HB71,P12270,Q8NFH4,Q15125,Q5SNT2,Q5UIP0,Q9UIS9,P67809,Q99567,Q9Y2U8,Q9NUL3,Q9NZZ3,P43243,O95619,Q9BTX1,Q13185,Q9H6Z4,P80303,Q9NQC3,Q96T37,Q03252 82 +Cell surface 0.3358463334385851 1.5087587572700447 0.1313604439147142 1.0 0.5861573693927403 80 O43847,P06576,Q99523,P42892,P04439,Q8WTV0,Q9HDC9,P08183,P41440,Q07021,Q8TCT9,P00813,Q04721,O96005,P10321,Q4VCS5,Q9UII2,P14174,P05067 19 +Neurofilament 0.8682014388489199 1.5080299245754658 0.1315468683785687 1.0 0.5861573693927403 2 P07197 1 +External side of plasma membrane 0.4631546767214255 1.4882371004428006 0.1366883762833948 1.0 0.6060962636175896 21 P08183,O96005,P41440,P42892,Q4VCS5,P00813 6 +Outer kinetochore 0.5885089444078915 1.4619644966632943 0.1437509391463978 1.0 0.6282192484811326 8 Q96EA4,Q96BD8,O60566 3 +Nuclear pore nuclear basket 0.6211218158801083 1.4488537968730069 0.1473784164118532 1.0 0.633381152602741 7 P49790,P49792,O60318,P41208,P52948 5 +Prefoldin complex 0.6852572806185745 1.4159057086634137 0.1568031133219258 1.0 0.645538392349338 5 Q99471,Q9UHV9,O15212 3 +Presynaptic cytosol 0.684376182221061 1.4119145972606566 0.1579751091006054 1.0 0.645538392349338 5 Q9UQB8 1 +Hulc complex 0.8437410071942436 1.4058430889883389 0.1597707238047481 1.0 0.645538392349338 2 O75150 1 +Mitochondrion 0.2460004677833926 1.3931736546937097 0.1635672844417321 1.0 0.6477029425973535 638 Q99595,Q96AY3,O60830,Q8IXJ6,P22830,P00846,Q9NS69,Q9BQT8,Q9Y2R0,O95831,Q9H773,Q9Y2Z9,P00374,Q8NBX0,Q69YU5,P30536,P30837,Q9NTG7,Q02252,Q9NUJ1,O43169,Q9NR28,Q9H7Z7,P23786,P45880,O43823,P53701,Q96NB2,O43772,P09874,Q13011,Q16540,O95169,P14406,Q9UDX5,Q6DKK2,Q15165,P21796,O43676,Q9NPH0,Q8N163,Q13423,Q9Y619,Q9UMX5,O75521,Q8N183,O00165,P14927,Q9Y5Y0,P31749,Q9HCC0,P09601,P13674,Q70HW3,Q8TAE8,P0DP25,Q9NX63,O00264,O75964,P06576,P28070,Q16134,Q9NR77,Q13505,Q9BY49,Q10713,Q08J23,Q9BXK5,P82970,P22695,Q07021,P00367,Q9H061,Q9UJS0,P48735,Q9Y3D6,Q9P013,Q8N4H5,Q8IYU8,Q9BSK2,P36551,Q9H2V7,Q5TC12,Q15118,O15228,Q5JRX3,P04150,Q9P0J0,Q9BYT8,Q13501,P13073,Q567V2 92 +Main axon 0.5268884054695516 1.3859247410722748 0.165769885169227 1.0 0.6477029425973535 11 Q8IXJ6 1 +Gap junction 0.7253990401624792 1.3677798230960676 0.1713810052169366 1.0 0.6520513880384678 4 Q69YQ0 1 +Dendritic shaft 0.632431994194709 1.365296924910374 0.172159745105999 1.0 0.6520513880384678 6 Q9UQB8 1 +Nuclear envelope lumen 0.6712047133840974 1.3521856654435245 0.1763159281555728 1.0 0.6563420295284026 5 P11717,P07437,P05067 3 +Outer membrane 0.3235651317210389 1.3476332477507658 0.1777763714847806 1.0 0.6563420295284026 89 P21796,Q9NS69,Q86UT6,Q13505,Q92667,O00165,P30536,Q9HCL2,Q9NQZ5,O43169,Q8IWA4,Q5XKP0,O75431,P45880,Q9Y277,Q9Y3D6,Q9NVT9,Q9NQG6,P09601,Q8N4H5,Q6NUM9,Q99720,Q8N0X7,Q9NX63,Q9Y512,Q8IWB1,Q8WY22,O00264 28 +Calcium channel complex 0.5629129674990803 1.3256941096285957 0.1849410393085095 1.0 0.6599262456025113 8 Q15257,P0DP25 2 +Cd40 receptor complex 0.7153993318733642 1.3251306416506696 0.1851278246739718 1.0 0.6599262456025113 4 Q96EP0,Q9NR28 2 +Myelin sheath 0.4882576528898872 1.2872137466175395 0.1980197971714687 1.0 0.6854081375071616 12 Q8IXJ6,P0DP25 2 +Integral component of cytoplasmic side of endoplasmic reticulum membrane 0.8135251798561137 1.2797535379890668 0.2006318290044597 1.0 0.6855301161997439 2 Q8TCT9 1 +Condensed nuclear chromosome 0.4268924318732167 1.2745505305801932 0.2024683766069506 1.0 0.6855301161997439 22 Q9NQS7,P16104,Q7Z5K2,P38398,Q92791,Q9HD42,Q92845 7 +Transcription export complex 2 0.8112230215827325 1.270164922828413 0.2040258895240077 1.0 0.6855301161997439 2 P41208 1 +Mcrd mediated mrna stability complex 0.6521777037213561 1.2657430650829504 0.2056050847857085 1.0 0.6855301161997439 5 O60506 1 +Intermediate filament cytoskeleton 0.3862022162468534 1.2617901707641934 0.2070243000006919 1.0 0.6855301161997439 32 P08670,Q16352,P48681,Q03252,P49761,P07197,P20700 7 +Proteasome core complex beta subunit complex 0.5781451586588122 1.2334233484396264 0.217417858362968 1.0 0.6972053128271611 7 P20618,P28072,P49721,P28070 4 +Protein lipid complex 0.6890900913374693 1.212856535237629 0.2251846759113838 1.0 0.7061727974185997 4 Q9UHG3 1 +Autophagosome membrane 0.4588278971391206 1.206348938152581 0.2276829755376848 1.0 0.7061727974185997 16 Q9Y6I9,Q9H444,Q9HD42,O95721,Q7Z3C6 5 +Respiratory chain complex iii 0.5689431275290353 1.187142601389395 0.2351713768789407 1.0 0.7200335375784837 7 P14927 1 +Ciliary basal body 0.3860555550994038 1.184916156639486 0.2360505986780947 1.0 0.7200335375784837 30 P28070,P31749,O43805,Q96C92,P41208,Q92845 6 +Pronucleus 0.5657261850575136 1.1709606149551717 0.2416146085843891 1.0 0.7284077584626891 7 P11166,O43823,P49454 3 +Apicolateral plasma membrane 0.5650685515193218 1.1676525683209438 0.24294693651593 1.0 0.7284210920535646 7 P46934 1 +Cis golgi network 0.446326473764754 1.1587372135429166 0.2465633170945178 1.0 0.7318812443026994 17 P98194,Q9UNK9,Q08379,Q8TBA6 4 +Cytosolic region 0.5301917781268348 1.1506694632762384 0.2498682438705941 1.0 0.7350492999300002 8 Q9UQB8 1 +Escrt i complex 0.7775539568345307 1.130492214298252 0.2582688772752368 1.0 0.7500524263360712 2 Q9H9H4 1 +Mitotic spindle microtubule 0.5259679335107228 1.128061668109484 0.2592938761463945 1.0 0.7506309981435434 8 Q96CS2 1 +Lipid droplet 0.3741129197043321 1.0763536955679072 0.2817691027698106 1.0 0.7788343080714565 30 Q9Y679,P48449,Q8NBX0,Q99720,Q8N0X7,Q07065,Q9H6V9,Q01105 8 +Amphisome 0.5162519351736402 1.0760870540596112 0.2818883249235524 1.0 0.7788343080714565 8 Q9HD42,Q9H444 2 +Sorting endosome 0.7602877697841708 1.0594552687988177 0.2893924904889626 1.0 0.7829100412335329 2 P18031 1 +Cytochrome complex 0.4343047406778515 1.0412207989088047 0.2977730848425512 1.0 0.7896840169779907 16 P22695,P14927,P14406 3 +Golgi stack 0.3504813176404006 1.038355539098553 0.2991045606905684 1.0 0.790366411824787 37 Q15363,Q8WVQ1,Q99523,Q8N6G5,Q8NBZ7,Q08379,P98194,Q96L58,Q10713,Q8TBA6 10 +Early endosome membrane 0.3266988988571375 1.0061881406901765 0.3143250758369649 1.0 0.8106876937327506 48 Q9Y5X2,Q8IV08,Q99816,Q9BZF3,Q15043,Q9UJ41,Q9UKG1,Q96T51,Q13596,O60749,P10321,P04439,A4D1P6,O14964,Q8N4V1,Q86Y82,P51790 17 +Caveola 0.4281280493714728 0.9997268718534628 0.3174427039446925 1.0 0.8128321630583817 16 P09601,Q8WTV0,P41440 3 +Pore complex 0.4910233083806293 0.9970213545253778 0.3187541447107409 1.0 0.8138975211855717 9 P21796,P45880 2 +Mib complex 0.4793160027352445 0.9913347812548344 0.3215221347685917 1.0 0.8141102127878567 10 Q5XKP0,O75431,Q9NX63,Q9Y512,Q13505,Q16891 6 +Escrt complex 0.4792964153524021 0.9912243122233196 0.3215760615001013 1.0 0.8141102127878567 10 Q99816,Q9H444,Q9HD42,Q9Y3E7,Q9H9H4 5 +Neuronal ribonucleoprotein granule 0.7602187679907799 0.989408601824874 0.3224632676576169 1.0 0.8141102127878567 3 Q99729,O60828 2 +Centrosome 0.2810319730333878 0.9840178861701562 0.3251067186380549 1.0 0.8141102127878567 189 Q8IXJ6,P16104,Q9Y5A9,O43805,Q15154,Q9H6D7,Q9H814,O95684,Q92845,P41440,Q9NS91,Q96C92,P37198,Q96ED9,P55081,O75935,O95721,Q13432,Q15051,Q92830,Q00013,Q8N1F7,P29966,P0DP25,Q96CS2,P53985,Q6DKK2,P41208 28 +Er membrane insertion complex 0.7517391149421421 0.9572866107944732 0.3384226114951731 1.0 0.8221905291119368 3 O43765 1 +Catalytic step 2 spliceosome 0.295460580037555 0.9381680528128176 0.3481580534303787 1.0 0.8284281323454141 72 O60506,Q07955,O60508,O43390,O95391,P51991,Q9UBB9,P62310,P31943,P38159,P61978,P52597,P22626 13 +Smc5 smc6 complex 0.744648344261761 0.9305374418223518 0.3520928875684057 1.0 0.8284281323454141 3 Q96SB8 1 +Rdna heterochromatin 0.6213992339353431 0.9259425838899172 0.3544758194257094 1.0 0.8284281323454141 4 Q96EB6 1 +Mediator complex 0.4299652948097444 0.9241058421425716 0.3554312118973723 1.0 0.8284281323454141 12 Q9NPJ6,Q9Y2W1,Q9NYF8 3 +Autophagosome 0.3410006456882221 0.908923163435896 0.3633906858627922 1.0 0.832420338417937 34 Q9NRR5,Q9Y6I9,Q9H444,Q8TBX8,O75787,Q13501,Q9P253,Q9HD42,O95721,Q7Z3C6 10 +Female pronucleus 0.5723082943863719 0.9042772693668756 0.3658483966555224 1.0 0.8355683230147484 5 P11166,O43823 2 +Spindle microtubule 0.3283688424716466 0.8945571038144183 0.3710238912476737 1.0 0.8431517928603386 42 P0DP25,Q96CS2,Q9H6D7,Q86Y91,Q9HD42,Q92845 6 +Cdc73 paf1 complex 0.6113360531677785 0.8839066171550198 0.3767466248529605 1.0 0.8464808031977117 4 Q8N7H5 1 +Dna replication preinitiation complex 0.4230688087119466 0.881531120660439 0.3780304175748212 1.0 0.8464808031977117 12 P33991,Q14566 2 +Mcm complex 0.5075616128929783 0.8797267466479303 0.3790073563272482 1.0 0.8464808031977117 7 Q14566 1 +Azurophil granule membrane 0.3877226578074931 0.8657187201091928 0.3866444315327768 1.0 0.8491644825731984 20 Q9NQX7,O95721,P42785,Q07065 4 +Transcription preinitiation complex 0.72674687400368 0.8635288824028287 0.3878467465417465 1.0 0.8491644825731984 3 Q00403 1 +Intrinsic component of peroxisomal membrane 0.5611213651122797 0.8544209757386296 0.3928717778142081 1.0 0.8491644825731984 5 P56589 1 +Dendrite cytoplasm 0.437042658980807 0.8543654805925508 0.3929025161411963 1.0 0.8491644825731984 11 Q6PJT7,Q9UQB8,P23246 3 +Intrinsic component of nuclear inner membrane 0.5003348168682782 0.8439722522705851 0.3986849112836017 1.0 0.8491644825731984 7 Q9UH99 1 +Proton transporting v type atpase v0 domain 0.6012236148119505 0.8419309212987598 0.3998266210575676 1.0 0.8491644825731984 4 Q93050 1 +Vacuolar proton transporting v type atpase v0 domain 0.6012236148119505 0.8419309212987598 0.3998266210575676 1.0 0.8491644825731984 4 Q93050 1 +Perikaryon 0.3707214414867679 0.8334605266309066 0.4045850511259017 1.0 0.8513473901720571 22 Q16637,Q8IXJ6,Q6Y7W6,Q96A49,P05067 5 +Mrna cleavage and polyadenylation specificity factor complex 0.4507608721313522 0.8312890792619196 0.4058103424315429 1.0 0.851920557206172 10 Q8N684,Q6UN15 2 +Crd mediated mrna stability complex 0.5196084762357841 0.8250254319045516 0.4093571523117862 1.0 0.8544829177640818 6 O60506 1 +Rna cap binding complex 0.4685826430313693 0.8231655659130538 0.4104138475550947 1.0 0.8544829177640818 8 Q53F19,Q06787 2 +Centriole 0.3303842007578983 0.8143069932435801 0.4154691044697225 1.0 0.8602765739475576 35 Q8IXJ6,Q86SX3,P41208,O95684,Q15051 5 +Escrt iii complex 0.5169197967518475 0.8123843692168026 0.416571112425641 1.0 0.8605087670931659 6 Q9HD42 1 +Basal part of cell 0.3048655587741224 0.8030666151919931 0.4219362325692313 1.0 0.8605087670931659 54 P41440,Q99808,P30825,P53985,P33527,P42785 6 +Pml body 0.3539179232593668 0.7997548769120897 0.4238528312671596 1.0 0.8605087670931659 26 P45973,Q9ULX6,Q96SB8,Q13501,Q01130,Q96EB6,Q9UER7 7 +Respiratory chain complex iv 0.4449984185228057 0.7993264763064464 0.4241011305365658 1.0 0.8605087670931659 10 P22695,P14406 2 +Lumenal side of endoplasmic reticulum membrane 0.4617235324654408 0.7873134470174018 0.4310983998349755 1.0 0.8669655872787451 8 Q8TCT9,P04439,P10321 3 +Intercellular bridge 0.3466083674909671 0.7572048972673248 0.448927116687144 1.0 0.8851946834460173 27 O43663,Q7Z5K2,Q13432,O95235,O75937,Q9ULW0,Q15051,P21266 8 +Inhibitory synapse 0.6840287769784146 0.7550212431751269 0.450236236139498 1.0 0.8858544126640773 2 P51790 1 +Endoplasmic reticulum tubular network membrane 0.6940330590253756 0.74351185675521 0.4571718457819278 1.0 0.8869658130196476 3 Q8NHH9 1 +Multivesicular body membrane 0.4531626057123928 0.7428642962907527 0.4575638437089648 1.0 0.8869658130196476 8 Q9HD42,Q9Y3E7,Q9H444,O14964 4 +Lateral element 0.6884639041653867 0.7234633281378837 0.4693952763867897 1.0 0.8869658130196476 3 P38398 1 +Spindle 0.2643660790734606 0.7230986494959094 0.4696192789474138 1.0 0.8869658130196476 176 Q8NEM2,Q8IXJ6,Q8N163,Q7Z5K2,P04150,Q13123,Q96JM3,Q9H6D7,Q9UJX3,Q92845,Q08J23,Q9H444,Q9HD42,Q9ULW0,P31749,P37198,Q96EA4,O75935,Q13432,Q15051,Q14166,P0DP25,Q96CS2,Q9H2V7,Q96SB8,Q08379,Q86Y91,P05067,Q96BK5 29 +Plasma membrane raft 0.3497293373045206 0.7219456112745232 0.4703279172009627 1.0 0.8869658130196476 23 P09601,Q8WTV0,P41440 3 +Amphisome membrane 0.4731078732052527 0.7109851898717923 0.4770934133948159 1.0 0.8886842474915732 7 Q9HD42 1 +Specific granule membrane 0.3869637168847768 0.70627373549288 0.4800179234814303 1.0 0.8923032565329657 15 P30519 1 +Vacuolar membrane 0.259518414495892 0.7018409104116458 0.4827783824920966 1.0 0.892704879934653 130 Q99523,P42892,Q93050,Q07065,Q8WTV0,Q9NQX7,P11117,P41440,Q9Y6I9,Q9H444,O15118,Q9P253,Q9HD42,Q9H0B6,O15260,Q14108,Q15043,Q16625,O75503,Q9UIQ6,O95721,P42785,Q9BTU6,Q9H2V7,O75787,Q5T3U5,Q7Z3C6 27 +Late endosome membrane 0.3142956058183435 0.6989952176585936 0.4845550195421935 1.0 0.8934290319753628 39 Q8IV08,Q99816,Q9UNK0,Q9H9H4,Q8TCT8,Q14108,Q15043,Q9H444,Q9H270,O14964,O15118,Q9NZZ3,A4D1P6,Q9P253,Q9HD42,Q9Y3E7,Q7Z3C6,P51790 18 +Extrinsic component of postsynaptic specialization membrane 0.6787759596850579 0.6888979353728167 0.490887498794184 1.0 0.9032727457569096 3 P52292 1 +Mrna editing complex 0.4783316216844347 0.6343143577533022 0.5258756882698246 1.0 0.9276864095349224 6 Q86U44,Q5T200,Q15007 3 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.5102380339578314 0.6334541580437243 0.5264371078751009 1.0 0.9276864095349224 5 P56385,O75964,O75947 3 +Basolateral plasma membrane 0.2979506624841981 0.628581921361834 0.5296227990603928 1.0 0.9276864095349224 45 P41440,Q99808,P30825,P53985,P33527 5 +Platelet dense granule 0.6494964028776951 0.6253606181341321 0.5317344031805773 1.0 0.9276864095349224 2 Q08380 1 +Prc1 complex 0.6557282671272213 0.6084517163650207 0.5428879201754562 1.0 0.9311121609499492 3 Q14781,Q8IXK0 2 +Nuclear pore outer ring 0.4266130550935219 0.607749814915979 0.543353418441614 1.0 0.9311121609499492 8 P57740,Q8NFH4 2 +Endoplasmic reticulum 0.2688297741434236 0.6065548248663366 0.5441463879561488 1.0 0.9311121609499492 506 P37268,Q96AY3,P30519,Q9BZF3,O95302,P07099,Q14257,Q9Y6I9,P30536,Q01105,Q9UQB8,Q92791,Q70UQ0,Q8IY17,Q02818,O95169,Q99720,P43307,Q9NWM8,Q15629,Q96G23,O75844,P05067,Q9NZ08,P67812,Q6UWP7,Q9UNK9,Q9Y680,O60725,Q86XL3,Q7Z2K6,Q9BQE5,Q9UMX5,Q9BRK5,O00165,O43681,Q9H4L5,Q06136,O15173,Q15392,Q9UBV8,O15460,Q9HD20,P09601,P13674,O43852,P56589,Q9Y282,O00264,O60506,O75718,P26885,O43390,Q9H6V9,Q92845,Q8N2G8,O00400,P00367,Q9NRR5,Q8WVQ1,Q14108,Q96LJ7,P10321,O75503,Q9Y3D6,Q6Y7W6,Q6NUM9,Q16850,P48449,P55327,Q96PC5,Q9P2W9,Q9H6E4,Q9BTY2,Q99523,Q9UBU6,Q8TBX8,Q13501,Q8IWX8,P27544,Q8NHH9,Q8TCT9,Q9H9S5,O75845,Q15363 85 +9plus0 non motile cilium 0.3722663216302044 0.5764864517791457 0.5642864247851316 1.0 0.9311121609499492 12 Q15051,Q92845 2 +Nuclear speck 0.2610218083309328 0.5743665406971141 0.5657197898057367 1.0 0.9311121609499492 191 Q07955,O75940,Q9Y2W1,P16104,Q93050,Q9ULX6,P04150,Q07065,Q13123,Q9UBB9,Q96FV9,Q9BT78,P98175,Q86V81,O60828,P43490,Q96MU7,P02545,Q13573,O75400,Q16629,Q5T200,Q9NTJ3,Q92841,Q15459,O95391,P49750,O75934,Q92733,O00330,P49761,Q96PK6,Q53F19,Q9P275,Q86U44,Q15020,P23246,Q6I9Y2,Q3ZCQ8,O60508,O75494,Q12874,Q9P013,Q01130,Q9UBU8,Q6PJT7,Q15233,Q86VM9,O43290,O15047,Q96RT1,Q86U42,Q8WXF0,Q13242,Q9H1I8,Q9BWF3,O75600,O95453,Q96T51,Q8WWY3,Q96SB8,O95400,Q9H2Y7,Q8WXF1,Q14191,Q9NYF8,P82979,Q15007 68 +Micos complex 0.4954737505409545 0.5718886327429056 0.5673974255338696 1.0 0.9311121609499492 5 Q5XKP0,Q9NX63,Q16891 3 +Mitochondrial crista 0.5327334040642919 0.5684139161514282 0.5697539432591596 1.0 0.9314862129902448 4 O60313,P18031 2 +Microtubule organizing center 0.2721210849052303 0.5622464748913186 0.5739481008173035 1.0 0.932496615327281 242 Q8IXJ6,P16104,P28070,Q9Y5A9,P04150,O43805,Q15154,Q9H6D7,Q9H814,O95684,Q92845,P41440,Q86SX3,Q9NS91,Q96C92,Q9HD42,P31749,P37198,Q96ED9,P08670,P55081,Q96EA4,O75935,O95721,Q15051,Q13432,Q92830,Q00013,Q8N1F7,P29966,Q14166,P0DP25,Q96CS2,P53985,Q6DKK2,P41208 36 +Respirasome 0.2878927036626427 0.5622141404758609 0.5739701282660272 1.0 0.932496615327281 47 Q13423,O43676,O95169,P14927,P14406,Q9P0J0,P22695,Q6DKK2,P13073,O96000 10 +Proton transporting v type atpase complex 0.3680394769939449 0.5614726608552039 0.5744753625778629 1.0 0.932496615327281 13 Q15904,Q93050,Q8N511,Q9Y5K8,O75787,P36543 6 +Germ cell nucleus 0.4165401998284986 0.5578696591359292 0.5769333912629322 1.0 0.9348172061640024 8 P16104 1 +Post mrna release spliceosomal complex 0.4370929535631956 0.5413916428996493 0.5882376662152164 1.0 0.9430476871069344 7 Q9UBB9,Q9P2K5 2 +Mitochondrial alpha ketoglutarate dehydrogenase complex 0.6230215827338099 0.5312067816310398 0.5952754940350302 1.0 0.9448177530693276 2 P09622 1 +Neuron projection terminus 0.3491824542906012 0.529444638819812 0.5964970390335407 1.0 0.9448177530693276 18 O75150,Q9UQB8,P05771,O75494,Q05682,Q2M2I8,P51790 7 +Sperm connecting piece 0.6221582733812919 0.5282269599194982 0.5973418194541966 1.0 0.9448177530693276 2 P10644 1 +Nuclear periphery 0.2638691221093799 0.5180922085383244 0.6043939361519928 1.0 0.9505088027027015 68 Q8N1F7,P23246,P02545,P08670,O75400,Q8WXF1,Q9ULX6,P52272,O43823,O95619,Q9HD42,P43243,Q05682,Q15233,P22626,P20700 16 +Rna polymerase ii transcription regulator complex 0.2981631779899457 0.511987863355957 0.6086595036433256 1.0 0.9539163600203152 36 Q00403,Q9NPJ6,Q99729,P23246,P29083,Q86U70,Q92830,Q15233 8 +Mrna cleavage factor complex 0.3593045127094401 0.5025719347191407 0.6152652653023507 1.0 0.9607222338625526 12 Q8N684,Q6UN15 2 +Microtubule minus end 0.6132374100719393 0.497800936538264 0.6186243557803477 1.0 0.9607222338625526 2 Q14980 1 +Gemini of coiled bodies 0.4464056935880571 0.4938621024134959 0.6214035706979946 1.0 0.9607222338625526 6 Q16637 1 +Sumo ligase complex 0.4761021768649474 0.4935355143196953 0.6216342524611898 1.0 0.9607222338625526 5 Q96SB8,Q96MG7 2 +Schaffer collateral ca1 synapse 0.3538384993387802 0.4893018845917857 0.6246279870327487 1.0 0.9607222338625526 14 Q9UQB8 1 +Dynactin complex 0.4739228629548856 0.4849164613786249 0.6277356049756606 1.0 0.9638710556129654 5 O75935 1 +Mhc class i protein complex 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.9639361061373388 3 P10321 1 +Mhc protein complex 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.9639361061373388 3 P10321 1 +Granular component 0.5090660815069756 0.4803770961708091 0.6309592773946278 1.0 0.9639361061373388 4 Q9NXV6 1 +Transcription regulator complex 0.2649639563309217 0.4719650092338092 0.6369517644331386 1.0 0.9665929113017078 89 Q9NPJ6,P53999,P09874,Q00403,P23246,Q99729,Q9NY61,O00165,O95983,P29083,P12956,Q92830,P51858,Q96PK6,Q15233 15 +Chromosome telomeric repeat region 0.4676583603568323 0.4603825086759809 0.6452416873606082 1.0 0.9698185165109752 5 P12956,Q9NYB0 2 +Mitotic spindle 0.2613932848979493 0.4507197486914346 0.6521915470376762 1.0 0.9751388492531076 75 Q8IXJ6,Q96CS2,Q96SB8,Q13123,Q9H6D7,Q08379,Q86Y91,Q9ULW0,Q15051,P37198 10 +Golgi medial cisterna 0.4997578351944939 0.4470066957216788 0.6548702254244885 1.0 0.9758639916571475 4 Q96L58 1 +Lumenal side of membrane 0.3767377645615044 0.4385707354337541 0.660972605646067 1.0 0.9772651341123048 10 Q8TCT9,P04439,P10321 3 +Intrinsic component of golgi membrane 0.3446946679006207 0.4284019570093475 0.6683585001238592 1.0 0.981482837823244 13 P98194,Q8N6G5,Q9Y282 3 +Protein phosphatase type 2a complex 0.4583269727033833 0.424541636635951 0.671170846715776 1.0 0.9824384857723676 5 Q15257 1 +Intrinsic component of mitochondrial outer membrane 0.3582868520619411 0.4170473235629157 0.676643793562927 1.0 0.9841107333579212 11 Q9UH62,Q8IWA4,Q9Y3D6,O96008 4 +Histone pre mrna 3 end processing complex 0.5885098928248164 0.3928602158357594 0.694422727042449 1.0 0.9894340622927748 3 O60506 1 +Zymogen granule 0.4841335576840816 0.3928175109302584 0.6944542703441037 1.0 0.9894340622927748 4 Q15363,P49755 2 +Rpap3 r2tp prefoldin like complex 0.4003913583914225 0.3803835639792662 0.70366071338964 1.0 0.9963803976008212 7 P19388,Q9UHV9,O15212 3 +Presynaptic active zone 0.3274447725782402 0.3747466535892816 0.7078488919097352 1.0 1.0 17 P05067,P41440 2 +Condensed chromosome 0.2489819874518039 0.3589108313920425 0.7196617964945868 1.0 1.0 118 P16104,Q96BK5,Q7Z5K2,P38398,P49454,Q96JM3,Q96MG7,Q92845,Q9Y3E7,P25054,Q9H444,Q9BXW9,P33981,P12270,Q8NFH4,Q9HD42,Q5UIP0,Q2NKX8,Q9NQS7,Q8NG31,Q12888,Q96EA4,Q92791,O43823,O75935,Q96DY7,Q9NZZ3,P45973,Q13185,Q9UEY8,Q96BD8,Q96SB8,Q13561,P57740,Q71F23,Q96DE5,O60566,Q9BS16,P52948 39 +Site of dna damage 0.2702288256091856 0.3562452381518193 0.7216569160992021 1.0 1.0 46 Q9NRR5,P09874,P02545,P16104,Q96SB8,Q9Y3Z3,Q14241,Q9NS91,Q9UGN5 9 +Distal axon 0.2548563321678178 0.343463101642289 0.7312500949915806 1.0 1.0 65 P51116,P51114,O75150,O75312,Q8IXJ6,P0DP25,Q99720,Q13561,O75494,P22681,Q96A49,Q05682,P05067,P05771 14 +Lamin filament 0.5644991695439991 0.3248007716851884 0.7453318604649231 1.0 1.0 3 P20700 1 +Endoplasmic reticulum plasma membrane contact site 0.5553956834532336 0.3193027770700726 0.7494969270242278 1.0 1.0 2 A0FGR8 1 +Gaba ergic synapse 0.3478045147725608 0.3025520740830378 0.7622312428280633 1.0 1.0 10 P41440 1 +Nuclear outer membrane 0.3335643916217549 0.2963537498273692 0.7669599419662452 1.0 1.0 11 Q6NUM9,Q99720 2 +Copii coated er to golgi transport vesicle 0.2739252852473786 0.2932806834523365 0.7693076171965074 1.0 1.0 36 Q15363,P10321,Q9UBV8,Q08379,Q9Y282,P05067 6 +Transcription factor tfiid complex 0.3570472044983066 0.2874903721607217 0.7737368728442169 1.0 1.0 8 Q00403 1 +Perinuclear region of cytoplasm 0.2511265571506859 0.2841806511358483 0.7762719426201339 1.0 1.0 211 Q8IXJ6,Q9BZF3,Q9Y605,Q9UNK9,Q99523,P42892,Q93050,Q07065,Q9NQX7,O95831,O95684,Q92905,O94788,P25054,Q8IWX8,Q9P266,Q14677,P22681,O15118,Q9H4L5,Q96A49,Q01105,P46934,Q9UL15,Q9NRR5,Q15056,Q9H7Z7,O75503,Q99627,Q9UIQ6,O75935,Q5SQN1,P09601,P51114,P55327,Q8NEW0,P05067 37 +Hops complex 0.4174053429131791 0.2791221099188118 0.780151115906321 1.0 1.0 5 Q9H270,Q9P253 2 +Replication fork 0.2703819641650251 0.2782996980785964 0.780782307864615 1.0 1.0 39 Q9Y6I9,Q9NS91,P16104 3 +Flotillin complex 0.3747236656264513 0.2780122128484061 0.7810029836879899 1.0 1.0 7 P41440 1 +Cilium 0.2503408307403477 0.2731490948343067 0.7847386088623716 1.0 1.0 98 Q04721,P28070,Q86SX3,P31749,P21266,O43805,Q92845,Q15154,P22681,Q96C92,P41208,Q13501,O95721,Q15051,P05067,A6NIH7,Q10713 17 +Kinetochore microtubule 0.3144309076738776 0.2707153191169249 0.7866099936797164 1.0 1.0 13 Q9HD42 1 +Nuclear cyclin dependent protein kinase holoenzyme complex 0.4443496952222898 0.2669656918078784 0.7894955766413605 1.0 1.0 4 P50750,Q9NYV4 2 +Nuclear pore 0.257768786555947 0.2561043516995364 0.7978702618490527 1.0 1.0 52 Q9BTX1,P49790,Q99567,Q8TD16,Q9BVL2,Q9H6Z4,Q9H444,P35658,P52948,O60318,P57740,P41208,Q8NFH4,Q9HD42,P37198,Q8N1F7 16 +Lysosomal lumen 0.2690751624172653 0.2493654234172985 0.8030781285942705 1.0 1.0 35 Q9UM22,Q9UMR5,O43681,Q8NHP8,P50897 5 +Site of polarized growth 0.2550013700789488 0.2406395021975648 0.80983453132689 1.0 1.0 55 P51114,O75312,Q8IXJ6,P0DP25,Q99720,Q13561,P22681,Q96A49,P05067,Q9BTU6 10 +Nuclear stress granule 0.5240287769784133 0.2387115474096572 0.8113292620442323 1.0 1.0 2 Q92797 1 +Beta catenin destruction complex 0.3639769452449477 0.2382746516358911 0.8116680802926604 1.0 1.0 7 P25054,Q9UJX6,P49840,Q9HB71,P49841,P35222 6 +Mitochondrial protein containing complex 0.2360187678575121 0.2334732203820977 0.8153939620407744 1.0 1.0 167 Q15118,Q99595,P21796,O75964,O60830,O43676,P06576,P00846,Q9NS69,Q9P0J0,Q13505,P13073,Q567V2,P14927,P22695,Q9HCC0,Q8N4H5,O96000,Q8IYU8,O75489,Q16540,O95169,P14406,Q9NX63,Q9Y512 25 +Specific granule 0.2639725186984304 0.2101565815830206 0.8335454656629435 1.0 1.0 36 Q8N2G8,Q96JM3,P30519,O00264 4 +Membrane microdomain 0.2397869032965816 0.209901385317796 0.8337446409894342 1.0 1.0 68 P21796,P07437,P41440,P22681,P46108,Q8WTV0,P09601,P05067,P50897,Q9BTU6 10 +Er ubiquitin ligase complex 0.3698397438554702 0.2023812145175093 0.8396187131876907 1.0 1.0 6 Q9UBU6,Q9Y679 2 +Postsynaptic membrane 0.2618611106855856 0.1900440530406605 0.8492746101861304 1.0 1.0 34 Q96A49,Q8NCG7,Q99720,P52292,O43815,O75787,Q96CX2,Q96EY1,P51790 9 +Cop9 signalosome 0.3232157337647331 0.1783692445120926 0.8584330012886696 1.0 1.0 9 Q92905,Q9BT78,Q99627 3 +Basement membrane 0.4070353719754725 0.1679550386549456 0.8666186504774727 1.0 1.0 4 Q96RT1 1 +Hippocampal mossy fiber to ca3 synapse 0.4057011229484611 0.164797573526972 0.8691033139748101 1.0 1.0 4 P47756,P63104,O60716 3 +Snare complex 0.2876340722807001 0.1624956153325613 0.8709155808486149 1.0 1.0 17 Q9P2W9,O95721,O60499,Q5SQN1 4 +Gamma secretase complex 0.4871942446043121 0.1609549633078187 0.8721288721321452 1.0 1.0 2 P49755 1 +Myosin ii complex 0.3976389288799321 0.14630831267338 0.8836780039104852 1.0 1.0 4 P35579,Q7Z406,P35580 3 +Podosome 0.2963946561274191 0.1404763121832936 0.8882836670354926 1.0 1.0 11 P61978 1 +Contractile ring 0.3689516129032387 0.1382081020672621 0.8900759520266206 1.0 1.0 5 P35579,O43663,P46939,Q9NQW6 4 +Photoreceptor inner segment 0.3480265053298788 0.1362085961308007 0.8916563797740955 1.0 1.0 6 Q15555,P05023,Q9HCM4,P11166,P35613 5 +Neurotransmitter receptor complex 0.4801381692573233 0.1355141936060307 0.8922053428968402 1.0 1.0 3 Q8N2K0,Q9BV23 2 +Ampa glutamate receptor complex 0.4801381692573233 0.1355141936060307 0.8922053428968402 1.0 1.0 3 Q8N2K0,Q9BV23 2 +External encapsulating structure 0.2544552764803248 0.133912871259012 0.8934714721691492 1.0 1.0 34 Q08380,Q32P28,P52272,P55081,Q53GQ0,Q9UBB9,P51858,Q92896 8 +Postsynaptic endosome 0.4716546762589883 0.1338567243780694 0.8935158711807818 1.0 1.0 2 Q86Y82 1 +Heterochromatin 0.253980406080163 0.1318518826585758 0.8951014483166071 1.0 1.0 36 P45973,Q8IXJ6,O95983,Q5T5X7,Q9UK61,Q96EB6 6 +Lateral plasma membrane 0.2653475882612468 0.1297095203490635 0.8967962500568751 1.0 1.0 23 P33527,P25054,P53985 3 +Kinesin complex 0.2788714520250667 0.1289398485905561 0.8974052452181926 1.0 1.0 18 O95235,Q92845,Q9H0B6,Q86Y91 4 +Early endosome 0.2387664703097935 0.1273312182464741 0.8986782528094155 1.0 1.0 104 Q9Y2I1,Q99816,Q9BZF3,Q99523,O00189,P04439,Q12768,Q9Y5X2,O95630,P41440,Q9UKG1,Q96C92,Q9P253,Q9HD42,P31751,Q9UNK0,Q15043,Q9UJ41,Q13596,P10321,Q9UIQ6,Q8N4V1,P18031,Q8IV08,P11717,Q96T51,P05067,P51790 28 +Chromosome telomeric region 0.2386407789807669 0.1250017502590283 0.9005221647029551 1.0 1.0 85 Q8IXJ6,P16104,Q96B01,P12956,O94761,Q9UBB9,Q9NYB0,Q00577,Q86V81,P22626,P33991,Q9Y619,Q96DT7,Q6I9Y2,P45973,P09874,Q96SB8,Q14566,Q14191,Q96BK5 20 +Phagophore assembly site 0.3286091136906428 0.122966408886661 0.9021336978752306 1.0 1.0 7 Q9H0U4,Q7Z3C6,Q13501,Q86Y82 4 +Nucleotide activated protein kinase complex 0.4703511801957282 0.1191446103051185 0.9051607885174366 1.0 1.0 3 P13861,P10644 2 +Myosin filament 0.4677605066205972 0.1150127026080809 0.908435053634878 1.0 1.0 3 P35579,P35580 2 +Spindle pole centrosome 0.336828505823013 0.1058200236520674 0.9157251494130044 1.0 1.0 6 Q15018,P50402,P06748,Q14980 4 +Presynapse 0.2378168816818355 0.1038482483606421 0.9172897767764412 1.0 1.0 97 P51116,O75150,Q2M2I8,Q92905,P41440,Q99808,Q9UI14,Q07021,Q9P253,Q96A49,Q05682,Q9UQB8,O14976,O43760,O75494,P11166,Q96CX2,Q5SQN1,O95721,Q9BTU6,P51114,P0DP25,P05771,P05067,P50897,P51790 26 +Proton transporting two sector atpase complex catalytic domain 0.2750482230370794 0.1033240573511892 0.9177057827960012 1.0 1.0 12 Q15904,P36543,Q9Y5K8,P06576 4 +Zymogen granule membrane 0.4551524624149059 0.0960997944678949 0.923441314543759 1.0 1.0 3 Q15363 1 +Mitochondria associated endoplasmic reticulum membrane 0.2984429065743778 0.0957334377506089 0.9237322833712284 1.0 1.0 9 P51572,O60488,Q9Y320,O96008,Q96N66,Q15388,Q96S66,O43865 8 +Spectrin associated cytoskeleton 0.4493379389752329 0.0880405243204359 0.929844467425564 1.0 1.0 3 Q12955,Q01082 2 +Centriolar satellite 0.252246665998581 0.0826362822096013 0.934140750892786 1.0 1.0 31 Q9UPN4,P41440,Q9Y5A9,Q15154,O43379,Q71F23,Q86UY6,Q00013 8 +Plasma membrane region 0.2388001233464017 0.074361644473568 0.9407226275477556 1.0 1.0 208 Q99523,Q8WTV0,Q92845,P08183,O95630,P25054,P41440,Q99808,O00165,Q9P266,P22681,Q96A49,P46934,Q14728,P31751,Q9UQB8,Q96D71,Q15043,P30825,Q16625,Q9UHB6,O75935,P09601,O95721,P36551,Q99720,P53985,P40855,P33527,P05067 30 +Filopodium 0.2450145472960488 0.0670624212642167 0.9465320100046966 1.0 1.0 34 P05067,Q9UQB8,Q9H4L5 3 +Multivesicular body 0.2640756535624509 0.0598315645315312 0.9522897857406843 1.0 1.0 15 Q99816,Q9H444,O14964,Q9HD42,Q96PU5,Q9Y3E7 6 +Cohesin complex 0.3320852534562241 0.0584450084189457 0.9533941644855162 1.0 1.0 5 Q8N3U4,Q8WVM7,Q9UQE7,O60216 4 +Condensed chromosome centromeric region 0.2320818358122013 0.0558985258891766 0.9554226451656376 1.0 1.0 82 Q96BK5,P52948,Q96JM3,Q9Y3E7,P25054,Q9H444,P33981,P12270,Q8NFH4,Q9HD42,Q2NKX8,Q9NQS7,Q8NG31,Q12888,Q96EA4,O75935,Q96DY7,Q9NZZ3,P45973,Q96BD8,Q13561,P57740,Q71F23,Q96DE5,O60566,Q9BS16,P49454 27 +Transcription export complex 0.2786036901433782 0.0505969447556661 0.9596466974406797 1.0 1.0 10 Q6I9Y2,Q86V81 2 +Rna polymerase ii transcription repressor complex 0.3879136690647437 0.0424087515146827 0.9661728519273708 1.0 1.0 2 Q9UHI6 1 +Integral component of synaptic vesicle membrane 0.3217165898617565 0.0405269138681358 0.9676730504990638 1.0 1.0 5 P20020,O60499,Q86Y82,O76024 4 +Cyclin cdk positive transcription elongation factor complex 0.4012221709743443 0.0365578239432123 0.9708375726505124 1.0 1.0 3 P50750 1 +Endoplasmic reticulum golgi intermediate compartment membrane 0.2471608808750157 0.0326524097969575 0.9739517751143776 1.0 1.0 26 Q15904,Q15363,P24390,O15260,Q9Y3B3,Q10472,Q9Y282,Q8N511,Q08379,O95070,P49755 11 +Mitochondrial pyruvate dehydrogenase complex 0.3040743444177298 0.0317802803832582 0.9746472726669104 1.0 1.0 6 Q15118 1 +Phosphatidylinositol 3 kinase complex 0.3839953943580796 0.0241109026112281 0.9807641468253216 1.0 1.0 3 O00443,Q08AM6 2 +Trna splicing ligase complex 0.2989016751190754 0.0221432337367716 0.9823336993853088 1.0 1.0 6 Q9BVC5 1 +Host cellular component 0.3765960386389458 0.0196039389076091 0.9843593216441526 1.0 1.0 3 P52292 1 +Spindle pole 0.2275286713528352 0.0178588776885078 0.9857514346281804 1.0 1.0 63 P0DP25,Q96CS2,Q96SB8,Q13123,Q96EA4,Q08379,Q9ULW0,Q13432,P37198 9 +Neuromuscular junction 0.2505072866064574 0.0140541896902211 0.9887867481735062 1.0 1.0 16 Q96EY1,P05067 2 +Proteasome core complex 0.2499837010463519 0.013994363089824 0.9888344782002718 1.0 1.0 15 P28072,P49721,P28070 3 +Preribosome small subunit precursor 0.2469367110298631 0.0116181291921471 0.990730282631814 1.0 1.0 13 Q9BVS4,Q96GA3 2 +Iswi type complex 0.262763195846557 0.0111606649579395 0.991095262605155 1.0 1.0 10 Q96T23,Q09028,Q9NRF9,P28370,Q16576,Q9NRL2,Q9NRG0,O60264,Q9UIG0 9 +Bcl 2 family protein complex 0.3592400690846203 0.0108036718738569 0.9913800846973128 1.0 1.0 3 Q07812,Q07820 2 +Side of membrane 0.2261163827302805 0.0046781234375109 0.9962674111502026 1.0 1.0 78 Q8TCT8,P42892,P04439,Q9NV70,P08183,P41440,Q9H444,O43464,Q96A49,Q8TCT9,P00813,P31749,O96005,Q9NR28,P10321,Q4VCS5,P18031,Q96EP0,O75787,P51790 20 +Male pronucleus 0.3390903857224967 0.0032937633634614 0.997371961817234 1.0 1.0 3 P83916,Q5UIP0 2 +Cortical endoplasmic reticulum 0.337651122625208 0.0028539648308521 0.9977228686156387 1.0 1.0 3 Q13586,P50402 2 +Nuclear body 0.2560544970097265 0.0025298301551551 0.9979814897308396 1.0 1.0 335 O75940,P18615,Q93050,Q07065,Q96EB6,Q86V81,P02545,O75400,Q92841,Q92733,Q96PK6,P23246,Q3ZCQ8,P52272,Q6PJT7,Q9UER7,Q15233,O15047,P45973,P09874,O75312,Q7Z417,Q96RU2,O95453,Q14191,P82979,P16104,Q9ULX6,P50750,P38398,P33240,Q9H814,Q9NYB0,O60828,P22626,Q00403,Q5T200,Q15459,O95391,P49750,Q9NS91,P49761,Q86UE4,Q16637,Q9NQS7,Q9UQ84,Q6I9Y2,Q8NG31,Q14978,Q01130,Q15637,Q13242,Q9H1I8,Q9BXP5,Q9BWF3,O95400,Q86Y91,Q9NVM9,P52948,Q07955,Q13123,Q9UBB9,Q96JM3,Q8WYQ5,P98175,P43490,Q659A1,Q8WW12,O75934,O00330,Q53F19,Q9P275,Q96RS0,Q99590,Q15020,Q06787,O60508,O75494,Q9P013,Q12874,Q9UBU8,Q96RT1,Q86U42,Q8WXF0,O75600,Q96T51,Q8WWY3,P38432,Q9H2Y7,Q8WXF1,O43290,Q9NYF8,Q15007,Q9Y2W1,Q6VMQ6,Q14562,P04150,Q96FV9,Q9BT78,Q13501,Q99436,Q96MU7,Q6NZY4,Q13573,Q16629,Q9NTJ3,Q9BXW9,Q5UIP0,Q86U44,Q9UIS9,Q01844,P35611,Q12888,Q9NYV4,Q9Y6X3,Q86VM9,Q9BPY3,O75489,Q96SB8 119 +Gamma tubulin complex 0.3308101882891851 0.0009204545944569 0.9992655835938667 1.0 1.0 3 P38398 1 +Vacuole 0.2392167095354896 0.0007512836905159 0.999400562398944 1.0 1.0 227 Q7Z3C6,Q9BTY2,Q99523,P42892,Q93050,Q9UM22,Q9UHG3,Q07065,Q8WTV0,Q8TBX8,Q13501,Q9NQX7,Q8NCC3,Q5BJF2,P07437,P11117,P41440,Q9Y6I9,Q9H444,O43681,O15118,Q9P253,Q9HD42,P00813,Q9H0B6,Q9NRR5,O15260,Q9NX40,Q14108,Q15043,Q16625,Q9H7Z7,Q13596,O75503,Q9UIQ6,Q8NHP8,Q01085,O95721,P42785,Q9BTU6,Q9H2V7,Q9UMR5,Q15165,P50897 44 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a51eeeb1b8c5f2018045c44b492c81011c937202 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body fiber", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine head", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of the cytoplasmic side of the plasma membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Photoreceptor connecting cilium", "Photoreceptor disc membrane", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Super elongation complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APC", "APEH", "APEX1", "APEX2", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC8", "ARMC9", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD5", "ATF7IP", "ATG3", "ATG9A", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf57", "C12orf73", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C3orf58", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC58", "CCDC86", "CCDC94", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CENPE", "CENPF", "CENPI", "CENPK", "CENPM", "CENPU", "CENPV", "CEP131", "CEP170", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CGN", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD8", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF7", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC2", "DSC3", "DSG2", "DSN1", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC8", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAM118B", "FAM126A", "FAM129B", "FAM162A", "FAM208A", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXL18", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLVCR1", "FMR1", "FNBP1L", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSD1", "FTH1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GTF2B", "GTF2E1", "GTF2F1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAUS7", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMGN5", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK1", "HOOK2", "HOXD13", "HP1BP3", "HPF1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "ISOC1", "IST1", "ITCH", "ITGB1", "ITM2C", "ITPK1", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JCAD", "JUP", "KARS", "KAT2A", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNL1", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM7", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP4K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED17", "MED23", "MED24", "MED4", "MEN1", "MEPCE", "MESD", "METTL1", "METTL13", "METTL14", "METTL3", "MFAP1", "MFN1", "MFN2", "MFSD10", "MGA", "MGAT2", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPHOSPH10", "MPHOSPH8", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTSS1L", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA20", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND4", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NF1", "NFKBIE", "NFS1", "NGDN", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NT5C3A", "NT5DC3", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OFD1", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBRM1", "PBX2", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF14", "PHF2", "PHF5A", "PHF6", "PHF8", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPFIBP1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABAC1", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RFX1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKA1", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD7", "STARD9", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAMM41", "TAOK1", "TAOK2", "TAP1", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGS1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE3", "TLK2", "TLN1", "TM7SF2", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT6", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTK", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TUT1", "TWF1", "TWF2", "TWNK", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UHRF1", "UNC119", "UNC119B", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS11", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VRK1", "VRK3", "VTA1", "WAPL", "WARS2", "WASHC4", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR61", "WDR62", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRAP73", "WRN", "WTAP", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBED1", "ZBTB10", "ZC3H13", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF106", "ZNF148", "ZNF326", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["AAK1", "AATF", "ABCB1", "ABCC1", "ABCC10", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ACBD5", "ACOT8", "ACOX1", "ACP2", "ACP6", "ACSL4", "ADA", "ADD1", "ADD3", "AGPS", "AHCYL1", "AIFM1", "AKAP1", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALDH1A2", "ALDH1B1", "ALDH6A1", "ALYREF", "AMOT", "ANAPC16", "ANAPC2", "ANAPC7", "ANGEL1", "ANK3", "ANKLE2", "ANLN", "AP4M1", "APC", "APMAP", "APOL2", "APP", "APPL1", "ARMC1", "ARMCX3", "ASCC2", "ASNA1", "ATF7IP", "ATG9A", "ATL2", "ATP13A1", "ATP1A1", "ATP2B1", "ATP2C1", "ATP5B", "ATP5H", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V1D", "ATP6V1E1", "ATPAF1", "ATPIF1", "ATXN2", "AUP1", "B3GALT6", "BAG5", "BAIAP2", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCL2L13", "BCLAF1", "BEND3", "BICD2", "BRCA1", "BRI3BP", "BSG", "BUB1B", "C12orf73", "C19orf70", "C1QBP", "C2orf49", "CACYBP", "CALD1", "CALM3", "CALU", "CANT1", "CAPZB", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR2", "CCDC134", "CD2BP2", "CDC23", "CDC40", "CDK12", "CDK9", "CDKN2AIP", "CENPF", "CENPK", "CENPU", "CEP131", "CERS1", "CERS2", "CETN2", "CHAMP1", "CHCHD3", "CHERP", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHRAC1", "CIRBP", "CKAP4", "CLCC1", "CLCN3", "CLINT1", "CLK3", "CLN5", "CLPTM1", "COA3", "COIL", "COPS4", "COPS5", "COPS8", "COQ6", "COX4I1", "COX7A2", "CPOX", "CPSF7", "CPT2", "CRK", "CRTAP", "CSGALNACT2", "CSTF2", "CTNNB1", "CTNND1", "CWC15", "CYB5B", "CYP51A1", "DAGLB", "DAXX", "DCTN2", "DCTN3", "DCTPP1", "DDX17", "DDX20", "DGCR8", "DHCR24", "DHFR", "DHRS1", "DHX8", "DIABLO", "DLD", "DNAJA3", "DNAJC1", "DNAJC8", "DTL", "EBP", "ECE1", "ECH1", "ECI2", "EI24", "EIF4H", "ELAVL1", "ELOA", "EMC2", "EMD", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "ERAP1", "ERBIN", "ERCC6L", "ERGIC3", "ERMP1", "ESYT2", "ETFDH", "EWSR1", "EXO1", "EXOC1", "FAM118B", "FAM208A", "FAM8A1", "FANCD2", "FDFT1", "FECH", "FGFR1OP", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLVCR1", "FMR1", "FUCA2", "FXR1", "FXR2", "GADD45GIP1", "GAK", "GALNT1", "GCAT", "GHDC", "GIGYF2", "GLG1", "GLUD1", "GNPAT", "GOLGA2", "GOLGA5", "GPAM", "GSK3A", "GSK3B", "GSTM3", "GTF2B", "GTF2E1", "H2AFX", "HAUS1", "HAUS4", "HAX1", "HCCS", "HDGF", "HGS", "HLA-A", "HLA-C", "HM13", "HMGN5", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HSD17B12", "HTRA2", "ICE2", "ICMT", "IDH2", "IGF2R", "IK", "IKBIP", "IMMT", "INA", "INCENP", "INPP4A", "INTS13", "IQCB1", "ITM2C", "ITPRIP", "JCAD", "KAT2A", "KCTD12", "KDELR1", "KDSR", "KIF18B", "KIF20A", "KIFAP3", "KLC2", "KNL1", "KPNA2", "L2HGDH", "LARP4", "LCLAT1", "LDAH", "LDB1", "LEMD3", "LGALS3BP", "LIMA1", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LSM3", "LSS", "LTV1", "LYN", "LYPLA1", "MAPRE2", "MARCKS", "MATR3", "MAU2", "MBD1", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM3AP", "MCM4", "MCM6", "MED4", "METTL3", "MFAP1", "MFN1", "MFSD10", "MIA2", "MICU2", "MIEF1", "MIF", "MINDY3", "MMGT1", "MORF4L1", "MPP1", "MPV17L2", "MRFAP1", "MRPL23", "MRPL40", "MRPS23", "MRPS25", "MRPS9", "MTBP", "MTDH", "MTFP1", "MTX1", "MTX2", "MYEF2", "MYH10", "MYH14", "MYH9", "NAA40", "NAMPT", "NCBP3", "NDC1", "NDUFA13", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB8", "NDUFS3", "NEDD4", "NEDD4L", "NEFM", "NELFE", "NENF", "NES", "NISCH", "NLN", "NLRX1", "NNT", "NOC4L", "NOLC1", "NONO", "NOTCH2", "NPC1", "NPM1", "NR3C1", "NRDC", "NSMCE3", "NSUN2", "NUCB1", "NUCB2", "NUDT12", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP214", "NUP37", "NUP54", "NUP58", "NUP62", "NUP88", "NUP93", "NUP98", "NUPL2", "OCIAD1", "OCLN", "OPA1", "OSBPL3", "OSBPL6", "OSBPL8", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPN1", "PAF1", "PARN", "PARP1", "PARP2", "PCM1", "PCNP", "PCYOX1", "PDHX", "PDK1", "PECR", "PEF1", "PEX14", "PEX19", "PEX3", "PFDN2", "PFDN5", "PFDN6", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF8", "PI4K2A", "PIK3C2A", "PINX1", "PIP4K2C", "PITRM1", "PLA2G15", "PLBD2", "PLD3", "PMPCA", "PNPLA6", "POLE3", "POLR2E", "PON2", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCC", "PRCP", "PRKAR1A", "PRKAR2A", "PRKCB", "PRPF31", "PRPF40A", "PRRC2C", "PSMB1", "PSMB2", "PSMB4", "PSMB6", "PSMB7", "PSPC1", "PTGES2", "PTPA", "PTPN1", "PUM1", "PURA", "PXMP2", "RAB1B", "RABAC1", "RABGEF1", "RAD18", "RAD21", "RAD51AP1", "RANBP2", "RANBP3", "RBBP4", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM3", "RBM4", "RBM5", "RBMX", "RBMXL1", "RCN2", "RECQL4", "REPS1", "RETSAT", "RIF1", "RIOK2", "RIPK1", "RNF123", "RNF31", "RNF40", "ROCK1", "RSF1", "RTN4", "RUFY1", "SAMHD1", "SAMM50", "SARNP", "SART1", "SART3", "SC5D", "SCAF11", "SCARB1", "SCARB2", "SCCPDH", "SCRN1", "SDCCAG3", "SDF4", "SEC11A", "SET", "SETD1A", "SF1", "SF3A1", "SF3A3", "SFPQ", "SFXN2", "SFXN4", "SGTA", "SHCBP1", "SIGMAR1", "SIRT1", "SIRT2", "SIRT3", "SKA1", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A33", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC39A14", "SLC7A1", "SLU7", "SMARCA1", "SMARCA5", "SMC3", "SMC4", "SMC6", "SMN1*", "SMNDC1", "SNAP29", "SNAP47", "SNW1", "SNX1", "SNX2", "SNX8", "SORT1", "SPART", "SPDL1", "SPECC1L", "SPNS1", "SPPL2A", "SPTBN1", "SQSTM1", "SRRT", "SRSF1", "SRSF10", "SRSF12", "SRSF2", "SRSF7", "SRSF9", "SSNA1", "SSR1", "STAG1", "STAG2", "STAMBP", "STARD7", "STAU2", "STIM1", "STRN", "STX10", "STX12", "STX18", "STX8", "SUB1", "SUN2", "SURF4", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "TARDBP", "TEDC1", "TERF2IP", "TEX264", "TFIP11", "TGS1", "THOC1", "THOC7", "THRAP3", "TIAL1", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TM7SF2", "TM9SF2", "TMED10", "TMED2", "TMED7", "TMEM126A", "TMEM199", "TMEM201", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMX2", "TMX4", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TP53BP1", "TPD52", "TPM4", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TSG101", "TSPAN10", "TSPO", "TTC19", "TTK", "TTLL12", "TUBB", "UBAP2L", "UBIAD1", "UBQLN4", "UBXN4", "UNC119", "UNC119B", "UQCRB", "UQCRC2", "USP28", "USP36", "UTRN", "UXS1", "VAC14", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS11", "VPS18", "VPS37B", "WAPL", "WASHC5", "WDR62", "WDR91", "WFS1", "WRN", "WTAP", "XRCC6", "YBX1", "YEATS4", "YIF1A", "YLPM1", "YTHDC1", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H13", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC8", "ZMPSTE24", 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1.3464702305086589 0.2177422235164347 7.182619081783866e-05 0.0020524288782531 1.2025466891765146e-05 5.100580211902312e-06 1.3219039302405263e-06 +Organic anion transmembrane transporter activity 10 33 3.564153290805128 0.0003650325932766 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.0012131463690276 0.0605318649589048 0.00132313066272 0.0010205325993841 0.0026801846148119 +Anion transmembrane transporter activity 15 51 3.5158562247994176 0.0004383382876511 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 0.0001526011466845 0.1184945425124205 0.001316320715177 0.000235412956108 0.0001252927918642 +Ion transmembrane transporter activity 27 109 3.402861449595902 0.000666840867399 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 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0.0038993066179735 6.357667188483331e-05 0.0005309775927247 0.0074273483269255 0.0470360579614364 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 11 34 2.8716467143492435 0.004083391853733 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.2652519382081038 0.0708561744170628 0.2248900268904883 0.0252029938936908 0.005404303083764 +Metallopeptidase activity 16 40 2.8223275196534807 0.0047676459794907 11.548543689320388 40.60436893203884 1.2053444242445344 0.3510417366391842 4.586289489033314 2.1135899474190585 1.0988837346562612 0.3462572593421246 0.0001433938169125 0.0543724481878489 0.0415809882988902 0.0006818386753638 5.966811022092003e-06 +Molecular transducer activity 12 34 2.743585187227095 0.0060772277847482 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.5561918345367151 0.1210408119033952 0.453147445932042 0.5984088454862694 0.8144012927760322 +Protein transporter activity 3 14 2.742709614255205 0.006093454492668 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 0.0117845073139748 0.0002094223372061 0.0016986126979642 0.0028478177309091 0.0312662716526952 +Nadplus adp ribosyltransferase activity 3 7 2.6811536483963083 0.0073368820111003 2.0242718446601944 4.771844660194175 -0.1174618868834078 0.5434694501009949 1.424267211989739 1.0480603884372752 0.9424509561496808 0.3147518376729288 0.0003280352666488 0.0814971443263516 0.0006327439593496 0.0007869115437374 0.0098879726868235 +Macromolecule transmembrane transporter activity 3 13 2.677173791118183 0.0074246112151894 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0062661916687399 0.0001055314719321 0.0008717411361388 0.0011993766429203 0.0144964406909979 +Exopeptidase activity 11 31 2.5479531796496584 0.0108357012753628 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 2.1070933905656242e-07 0.2507644527164699 0.0002876902013005 1.7668988403556937e-06 3.0842490268484224e-05 +Sphingolipid binding 2 7 2.523767083488469 0.011610482661813 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.004613560888322 0.0814971443263516 0.0126574737404708 0.0087554356838108 0.0544656750173612 +Monooxygenase activity 6 10 2.504672301608549 0.012256489139905 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.0943570240414836 0.0070670490819082 0.0274603336438859 0.0267619345648551 0.000237302398801 +Ceramide binding 2 5 2.457981067398158 0.0139720539708034 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 0.0017355285880705 0.0595353304203936 0.0066572828402184 0.003355333516566 0.0228394808772788 +Fk506 binding 2 7 2.4158255943737283 0.01569957915864 1.983009708737864 6.422330097087379 0.7710035079475605 0.4104541026784208 1.4588872837549367 0.7512361384385784 1.0178387667233504 0.3228401619923597 0.0121098863456871 0.04159641685533 0.0832836732680532 0.0188064524051028 0.0077568745967145 +Macrolide binding 2 7 2.4158255943737283 0.01569957915864 1.983009708737864 6.422330097087379 0.7710035079475605 0.4104541026784208 1.4588872837549367 0.7512361384385784 1.0178387667233504 0.3228401619923597 0.014947386852539 0.0461123069087121 0.0921025797166938 0.0231366382468947 0.010684483318579 +Cholesterol binding 7 15 2.383150426657762 0.0171651785600583 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0002404022147528 0.0086801325315587 0.0028960612595367 0.0006954184772239 0.0028413691736374 +Zinc ion binding 24 151 2.3741047249503966 0.0175915602495431 28.59223300970874 139.68203883495147 -0.0405402661254739 0.6975438866599186 14.186474409757915 17.65179293730256 0.7773657878061386 0.3244829078143309 0.0088060518118762 0.4296224261104949 0.1140087027387602 0.0668774338650881 0.3437004297692158 +Pentosyltransferase activity 4 18 2.369110800495002 0.0178309107738556 3.4902912621359223 14.83495145631068 0.505106860173779 0.5013954818230527 2.980910610955346 1.7850353529372307 0.8822987908980519 0.306436524222116 0.0009501042182933 0.1723099894081314 0.0065760397653667 0.0026376358858749 0.0435237537141962 +Modified amino acid binding 5 20 2.3430035931857502 0.0191291988680186 4.446601941747573 21.354368932038835 0.8157790161756342 0.4133026066112408 2.099367243274066 1.7995833767593454 0.9656025978141096 0.3166170247143811 0.0133294896053514 0.0213334360876883 0.0011293669878184 0.0284489140367958 0.0281454476703931 +Prenyltransferase activity 6 12 2.335940523798345 0.0194943415484387 2.099514563106796 6.009708737864078 0.6003375563696288 0.3888587975741492 1.4081247453019228 2.026499903013553 1.0962032128239394 0.3008779016140248 0.0327528823448254 0.0683810764565047 0.1349531130589082 0.0498779046475234 0.0338099842169397 +Serine type carboxypeptidase activity 3 5 2.332448686658713 0.0196770993810728 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 6.80006495385603e-05 1.0 0.0008973897437505 0.0001354907423541 2.682481879206317e-05 +Sterol binding 7 18 2.3213578515669595 0.020267538328784 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0005792468221625 0.0123481232007499 0.004885623522166 0.0016346598494465 0.0072821786511837 +Lipid binding 28 152 2.3144892338443075 0.020640901138939 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0263633940855377 0.0180663933163214 0.0667745052255508 0.024847081862894 0.0733059330460842 +Organic cation transmembrane transporter activity 2 5 2.295407384585818 0.0217097885506221 1.9271844660194175 5.04126213592233 1.6158747778246996 0.14183106997637 1.275055237696066 0.9168044752551467 0.8418646651592007 0.1871331589544055 0.0287436893658769 0.0639684350193291 0.0077184558590264 0.0041946485896371 0.0280386150660574 +Iron ion binding 9 23 2.249890824557904 0.0244558765423934 6.524271844660194 22.196601941747577 0.9076096695164306 0.382669917893863 2.4429198675966717 3.289094676807881 0.9378690899634522 0.3126784916965753 0.3282231214235469 0.2507644527164699 0.4461675288226883 0.0600215848699845 0.0026068114295301 +Translation repressor activity 1 8 2.240781729756974 0.0250402169737768 2.621359223300971 8.691747572815533 0.8178109552751379 0.3869214297451314 1.7535899646617803 1.1146116282865457 0.9030508481280868 0.2968248594231644 0.0607884384663988 0.0043047615253927 0.0170518298819148 0.090818300458346 0.2730711037423907 +Fad binding 5 11 2.2315764702769094 0.0256429682114469 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.0131362594618491 0.0065631621549981 0.0255840399150975 0.0033024410276518 0.0012998754323988 +Nadplus binding 3 9 2.228508821620024 0.025846603733884 2.063106796116505 6.075242718446602 0.303198443969263 0.5359207535361904 1.358503623620749 1.1810266594001888 0.8660083880546793 0.2978074759031641 0.0026839350013314 0.0021914548918381 0.0003602808960722 0.0051503840765812 0.0049531384619904 +Lipopolysaccharide binding 2 7 2.2250473774421047 0.0260780578021777 1.3325242718446602 6.762135922330097 0.8069967393930578 0.3801019166455804 1.1293139239074608 0.4639669608371066 0.8740381370360097 0.2828250429158399 0.1438733856834229 0.0370595951599339 0.0743799864466655 0.1781979724676324 0.0053637976870067 +Endopeptidase activity 29 67 2.2209709707186738 0.0263529276367642 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 0.0410765107899016 0.5460422758388164 0.4761179790057352 0.1086232554691512 0.0320238215153129 +Cis trans isomerase activity 5 30 2.0806138188933896 0.0374692680087722 5.888349514563107 25.25728155339806 0.2561980004465105 0.5812219045702732 3.257874730761561 2.895731775037304 0.9309473322387666 0.3210818323454172 0.0007476244520781 0.0136970422924113 0.0513963234576887 0.0020925837152473 0.0095095891823194 +Alcohol binding 7 18 2.078033877668368 0.0377062389760638 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0026202999338889 0.0230307909848423 0.0121763996061805 0.006984722202598 0.0336187943157164 +Amyloid beta binding 3 10 2.0671769805227243 0.0387174804526524 3.5898058252427183 10.560679611650484 1.053866189591651 0.2544642672774957 2.009490338022764 1.9342863324228672 1.0942484681219342 0.2534200432416059 0.1585320343095167 0.1604648724397155 0.3009165941166509 0.2256009180273313 0.2688137047180795 +Proton channel activity 2 11 2.055281270592677 0.0398518452822667 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 0.2812476453561096 0.0771453392642774 0.1515272625734178 0.3411306657380243 0.0470360579614364 +Proton transporting atp synthase activity rotational mechanism 2 11 2.055281270592677 0.0398518452822667 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 0.2671375230127674 0.0727733471903131 0.1432798584585485 0.3247468214281712 0.0401461367370898 +Amino acid transmembrane transporter activity 3 10 2.0539550257657493 0.0399800448029208 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 0.0410866703643027 1.0 0.0563311776114605 0.0720513532108381 0.1288473164062758 +Peptidase activity 26 123 2.041636562541421 0.0411875956839589 29.021844660194176 113.626213592233 1.2572335980018865 0.3731282983707893 8.334453494010912 9.805689463637474 1.5136028692995414 0.3922229485757941 0.0001582896954604 0.401561077003812 0.0222030587712471 0.0019759955585733 0.0010275406291147 +Symporter activity 4 10 2.034092091022328 0.0419423112484607 3.638349514563106 9.1747572815534 0.9770544165414302 0.3122690599192905 2.3735568316725377 2.065327188945721 1.1044541290009051 0.3081067804681572 1.0 1.0 1.0 0.6608597677231411 0.1653068273939545 +L amino acid transmembrane transporter activity 2 7 1.9921627452419532 0.0463532043659611 3.628640776699029 8.201456310679612 0.919975936290114 0.2876791162304417 2.2759730869054327 1.0290432051153906 1.15482978403653 0.2925518180165951 0.1065011954383621 1.0 0.2445730022705269 0.1552222190730896 0.1659016353191164 +Xenobiotic transmembrane transporter activity 4 6 1.989142718440384 0.0466854523429913 1.3530864197530863 3.340740740740741 0.8982984875737676 0.3051772799543666 0.9692922732850732 1.0505469213791474 1.1959004084194096 0.2729390864460656 0.0327528823448254 0.0683810764565047 0.1349531130589082 0.0498779046475234 0.0338099842169397 +Nad binding 7 33 1.966171693200792 0.0492787811049864 8.563106796116505 29.28640776699029 -0.1611005483208177 0.4805202036040635 4.8695006879309135 2.252401029309141 1.131878946797942 0.3253122423834694 0.0001575744049643 0.0010588512016677 0.0007430351028178 0.0005468287448316 0.000965206072546 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..167b3bbc3e2d1ba451e96da82c362ed30d043c09 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 1400, + "title": "Average number of proteins per term", + "value": 17.68857142857143 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..cfcc31feae7b42e1128dce8be57e1b9b726073d6 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0efec3785ad4b3f003ee2c566de0f91e35baf862 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,400 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.4302363255173034 3.805626350564359 0.0001414457833697 0.179661404716716 0.0408203962869449 184 Q99595,P21796,O75964,O60830,O43676,P06576,Q9BZF3,P00846,Q96ES6,Q9NS69,Q9P0J0,Q9BQT8,Q8WTV0,P13073,P08183,Q13423,Q9Y619,P41440,O00400,Q99808,P30536,O43681,Q9H4L5,Q9Y5Y0,Q14728,Q9UJS0,Q9C0H2,O15173,Q99567,Q15043,P30825,P45880,Q9Y277,Q9HD20,P98194,O96000,Q9BSK2,Q96NB2,O43772,Q70HW3,O95169,Q8IXU6,Q9H2V7,P53985,P51991,Q8NEW0,P33527 47 +Tetrapyrrole binding 0.8615801956080407 3.7291630849940702 0.0001921167883267 0.2358486009630531 0.0448272506095769 17 O00264,P30519,O15173,Q6UW02,Q9H7Z7,Q9NRV9,Q8WUJ1,Q9Y5Y0,Q8WYQ5,O43169,P53701,P09601 12 +Organic anion transmembrane transporter activity 0.6454012099775889 3.5641532908051277 0.0003650325932766 0.4001879527646617 0.0550023847971382 33 O00400,P41440,Q9Y619,Q99808,P30825,P53985,Q9BQT8,P33527,Q96NB2,Q14728 10 +Anion transmembrane transporter activity 0.5535424471167445 3.5158562247994176 0.0004383382876511 0.4587143524697726 0.0557885093374209 51 P21796,Q9UJS0,Q9C0H2,O00400,P41440,Q9Y619,Q99808,P30825,P45880,O43681,P53985,Q9BQT8,P33527,Q96NB2,Q14728 15 +Ion transmembrane transporter activity 0.4471574092592457 3.402861449595902 0.000666840867399 0.606977582410681 0.0678924006893747 109 P21796,O75964,P06576,P00846,Q96ES6,Q9BQT8,P13073,Q13423,Q9Y619,P41440,O00400,Q99808,O43681,Q14728,Q9UJS0,Q9C0H2,Q15043,P30825,P45880,Q9Y277,Q9HD20,Q96NB2,O43772,Q70HW3,P53985,Q8NEW0,P33527 27 +Organic acid transmembrane transporter activity 0.6797678392857681 3.2315728159477506 0.0012311095242731 0.8217583645983128 0.0678924006893747 23 P08183,Q9Y619,P41440,P30825,P53985,Q9BQT8,P33527,Q96NB2 8 +Calcium ion binding 0.4462975844539206 3.085565582968713 0.0020316541379312 0.9419940127589084 0.0678924006893747 88 Q96AY3,O95302,Q9UM22,Q9Y680,Q14257,Q9BRK5,O43681,P22681,Q9UJS0,Q04721,Q8WVQ1,Q96D71,Q9UBV8,P67936,Q8IYU8,O43852,Q02818,P0DP25,P55327,Q9NWM8,P41208 21 +Cation transmembrane transporter activity 0.4462065755001438 2.9900854305853435 0.0027889943177241 0.9799604434748408 0.0703103337658384 73 Q8NEW0,O75964,Q13423,O43772,O00400,P06576,Q9Y619,Q99808,Q15043,Q96ES6,P00846,P30825,Q70HW3,Q9HD20,P98194,P13073,Q96NB2 17 +Steroid binding 0.6299895650376193 2.928465831975086 0.0034063926982634 0.991579539223651 0.0780524152616991 24 P21796,Q9BZF3,P35610,O15173,Q14108,P30536,P04150,P45880,Q9H4L5,O00264 10 +Metalloendopeptidase activity 0.7501706887515356 2.9189293048428517 0.0035123586867764 0.9927442288089162 0.0780524152616991 14 O43847,P42892,Q5JRX3,P22695,Q9BYT8,O75844,Q10713 7 +Protein transmembrane transporter activity 0.7621804500900791 2.88554292956315 0.0039073916781415 0.995835102726718 0.0828840658999729 12 Q99595,O60830 2 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5513579596667012 2.8716467143492435 0.004083391853733 0.996747893468386 0.0840698322827398 34 O75845,Q16850,Q9UPP1,P30519,Q6UW02,Q9BU89,O15460,P61457,P13674,Q9Y2Z9,P09601 11 +Metallopeptidase activity 0.5245879092910036 2.8223275196534807 0.0047676459794907 0.998757545523818 0.0878250575169349 40 P55786,O95630,O43847,Q9NZ08,P36551,O75844,P42892,Q5JRX3,Q9UIQ6,Q9BYT8,P22695,P09960,Q9HD42,Q7Z2K6,O75976,Q10713 16 +Molecular transducer activity 0.536489745745191 2.743585187227095 0.0060772277847482 0.9998033484169964 0.0986779346570247 34 Q04721,O15173,Q99523,Q9Y6I9,Q14108,P30536,P04150,Q99720,O15118,Q8WTV0,Q4VCS5,Q15629 12 +Protein transporter activity 0.7187236777363277 2.742709614255205 0.006093454492668 0.9998077922019818 0.0986779346570247 14 Q99595,O60830,Q9NS69 3 +Nadplus adp ribosyltransferase activity 0.8821605067638625 2.6811536483963083 0.0073368820111003 0.9999666849405968 0.1094153231712129 7 Q9NTG7,Q9UGN5,Q8IXJ6 3 +Macromolecule transmembrane transporter activity 0.7157116198089281 2.677173791118183 0.0074246112151894 0.9999705623227502 0.1094153231712129 13 Q99595,O60830,Q9NS69 3 +Exopeptidase activity 0.535870721085012 2.5479531796496584 0.0108357012753628 0.999999762421814 0.1391741448211738 31 P55786,Q9H3G5,O75844,Q9HB40,Q9UIQ6,P09960,P42785,Q12765,Q7Z2K6,O75976,Q9NZ08 11 +Sphingolipid binding 0.8468505048099187 2.523767083488469 0.011610482661813 0.9999999206799464 0.1425848747941957 7 Q9UM22,P45880 2 +Monooxygenase activity 0.7570286266921328 2.5046723016085495 0.012256489139905 0.9999999682415518 0.1479231447919577 10 Q16850,P30519,Q6UW02,P61457,Q9Y2Z9,P09601 6 +Ceramide binding 0.9246866021099008 2.457981067398158 0.0139720539708034 0.999999997214434 0.1577649418056924 5 Q9UM22,P45880 2 +Fk506 binding 0.8230110876252513 2.4158255943737283 0.01569957915864 0.999999999760812 0.1690723909392006 7 Q96AY3,Q9Y680 2 +Macrolide binding 0.8230110876252513 2.4158255943737283 0.01569957915864 0.999999999760812 0.1690723909392006 7 Q96AY3,Q9Y680 2 +Cholesterol binding 0.6485548361024379 2.383150426657762 0.0171651785600583 0.9999999999703004 0.1806860901058778 15 P21796,Q9BZF3,Q14108,P35610,P30536,P45880,Q9H4L5 7 +Zinc ion binding 0.3412196622262478 2.3741047249503966 0.0175915602495431 0.9999999999838224 0.1826552678140142 151 Q8IXJ6,P42892,Q5JRX3,P04150,Q8NCC3,P55786,Q00403,O95391,Q9NTG7,Q9BQG2,Q9Y3Z3,Q9HD42,P00813,Q05682,O75976,Q8N4Q0,Q9UIQ6,O43823,P09874,Q9UPP1,P36551,P09960,Q9NZ08,P05771 24 +Pentosyltransferase activity 0.6177989912199687 2.369110800495002 0.0178309107738556 0.9999999999884982 0.1826552678140142 18 Q9NTG7,P09874,Q9UGN5,Q8IXJ6 4 +Modified amino acid binding 0.5917548200359772 2.3430035931857502 0.0191291988680186 0.9999999999981948 0.1912919886801867 20 P00374,P41440,Q9H7Z7,Q8WTV0,P21266 5 +Prenyltransferase activity 0.6628439165445993 2.3359405237983455 0.0194943415484387 0.999999999998928 0.1935608380696047 12 P37268,Q9Y5Z9,Q86YH6,Q5T2R2,P49356,O95749 6 +Serine type carboxypeptidase activity 0.8945403930708327 2.332448686658713 0.0196770993810728 0.9999999999991744 0.1939995713626902 5 Q9H3G5,P42785,Q9HB40 3 +Sterol binding 0.610429623606378 2.3213578515669595 0.020267538328784 0.9999999999996448 0.1984234521699135 18 P21796,Q9BZF3,Q14108,P35610,P30536,P45880,Q9H4L5 7 +Lipid binding 0.3383496280879913 2.3144892338443075 0.020640901138939 0.9999999999997916 0.1992914592725146 152 P21796,Q9BZF3,P28070,Q9UM22,P04150,Q8WTV0,Q96JM3,Q8NCC3,A6NIH7,O94788,Q9BQE5,P30536,Q15067,Q9NQZ5,Q14677,Q9H4L5,P31749,P37198,O15173,P53367,Q14108,P45880,Q7KZI7,Q13432,P56589,Q5T8D3,P50897,O00264 28 +Organic cation transmembrane transporter activity 0.8857246556424055 2.295407384585818 0.0217097885506221 0.9999999999999548 0.2027556573661068 5 Q99808,O43772 2 +Iron ion binding 0.5422981217504727 2.249890824557904 0.0244558765423934 0.9999999999999992 0.2166976402490559 23 O75845,Q16850,Q9UPP1,Q6UW02,P22830,Q9BU89,O15460,P13674,Q9BV57 9 +Translation repressor activity 0.740030969686714 2.240781729756974 0.0250402169737768 0.9999999999999996 0.2191018985205478 8 Q14011 1 +Fad binding 0.6746995347366128 2.2315764702769094 0.0256429682114469 1.0 0.2219953694934825 11 O00116,Q15392,Q15067,O95831,Q9Y2Z9 5 +Nadplus binding 0.7206839148539952 2.2285088216200237 0.025846603733884 1.0 0.2219953694934825 9 Q9NTG7,Q8NBZ7,Q8IXJ6 3 +Lipopolysaccharide binding 0.7815961643881688 2.2250473774421047 0.0260780578021777 1.0 0.2226175666039564 7 Q8WTV0,P28070 2 +Endopeptidase activity 0.3903483618472147 2.2209709707186738 0.0263529276367642 1.0 0.2236005981301206 67 P67812,O43847,Q96K76,P28070,Q8TCT8,Q5JRX3,P42892,Q9BYT8,Q92905,Q10713,Q4J6C6,P51784,P20618,P22695,O43464,Q8TCT9,Q9P275,Q8NB14,Q99797,Q9Y4P1,P49721,Q9Y4E8,P28072,Q6NTF9,Q96RU2,P42575,O75844,Q16740,Q9NZ08 29 +Cis trans isomerase activity 0.4868835170925116 2.0806138188933896 0.0374692680087722 1.0 0.277550133398313 30 Q96AY3,O95302,Q9Y680,Q15257,Q9NWM8 5 +Alcohol binding 0.5734516600731041 2.078033877668368 0.0377062389760638 1.0 0.2778354450867862 18 P21796,Q9BZF3,Q14108,P35610,P30536,P45880,Q9H4L5 7 +Amyloid beta binding 0.672974182241618 2.0671769805227243 0.0387174804526524 1.0 0.282314961633924 10 Q8WTV0,O15212,O00264 3 +Proton channel activity 0.6429161039551842 2.055281270592677 0.0398518452822667 1.0 0.2841221458075592 11 O75964,P00846 2 +Proton transporting atp synthase activity rotational mechanism 0.6429161039551842 2.055281270592677 0.0398518452822667 1.0 0.2841221458075592 11 O75964,P00846 2 +Amino acid transmembrane transporter activity 0.670496126525302 2.0539550257657493 0.0399800448029208 1.0 0.2841221458075592 10 P30825,Q9Y619,Q96NB2 3 +Peptidase activity 0.3413621577607529 2.041636562541421 0.0411875956839589 1.0 0.2897619796861431 123 P67812,P28070,P42892,Q5JRX3,Q9BYT8,Q7Z2K6,Q10713,P55786,Q4J6C6,O95630,Q9HB40,P22695,Q12765,Q9HD42,O75976,Q9Y4P1,Q01804,Q9UIQ6,P49721,P42785,Q9H3G5,P36551,Q96RU2,P09960,O75844,Q9NZ08 26 +Symporter activity 0.6667798218543901 2.034092091022328 0.0419423112484607 1.0 0.2921355012330596 10 Q15043,Q96ES6,O00400,P53985 4 +L amino acid transmembrane transporter activity 0.7322085505108569 1.9921627452419537 0.0463532043659611 1.0 0.3032452622072223 7 P30825,Q9Y619 2 +Xenobiotic transmembrane transporter activity 0.7652373556231384 1.9891427184403836 0.0466854523429913 1.0 0.3039982943264554 6 P08183,Q5T3U5,P33527,P41440 4 +Ribosomal protein s6 kinase activity 0.9792805755395684 1.968407005521582 0.0490212264909422 1.0 0.3148152159968765 2 P51812 1 +Nad binding 0.4564869950394218 1.966171693200792 0.0492787811049864 1.0 0.3150241714474017 33 Q13423,P09874,Q8IXJ6,Q8NBZ7,P30837,Q9NTG7,P00367 7 +Nad dependent protein deacetylase activity 0.8040960058961233 1.9454154299231552 0.0517249991513963 1.0 0.3285694906478021 5 Q8IXJ6 1 +Structural constituent of nuclear pore 0.5442962508356602 1.944235646374098 0.0518670410236887 1.0 0.3285694906478021 19 Q9BTX1,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,P12270,Q9BZI7,P37198,Q8N1F7 11 +Solute cation symporter activity 0.6796575726403971 1.9372491903591984 0.0527148898976814 1.0 0.3324362425979913 8 Q15043,Q96ES6,O00400 3 +Serine type exopeptidase activity 0.7160237766063848 1.91460108898352 0.0555433961570888 1.0 0.3431562404091993 7 Q9H3G5,P42785,Q9HB40 3 +Protein phosphatase 2a binding 0.6178485057101997 1.9139225637505437 0.0556300508519389 1.0 0.3431562404091993 11 P18031,Q9UPR3,Q15257,Q86XL3,P78318 5 +Lipase activity 0.5298928041522266 1.9108737649477072 0.0560208052653283 1.0 0.3431562404091993 20 Q8IY17,Q9NZC3,Q8NHP8,Q9H6V9,P09601,Q8NCC3 6 +Protein deacetylase activity 0.7478802872141954 1.909440289675236 0.0562053175371222 1.0 0.3431562404091993 6 Q8IXJ6 1 +Phospholipase activity 0.5706515737930253 1.9019880632726376 0.0571727151459759 1.0 0.3445004892175359 15 Q8IY17,Q9NZC3,Q8NHP8,P09601,Q8NCC3 5 +Oligopeptide binding 0.7932431141757236 1.8979598939156068 0.0577013654435698 1.0 0.3445004892175359 5 P21266 1 +Lysophosphatidic acid phosphatase activity 0.961438848920863 1.8951469231960616 0.058072939610956 1.0 0.3445004892175359 2 P34913 1 +Sulfur compound transmembrane transporter activity 0.6400855617428862 1.890229977654431 0.058727209051512 1.0 0.344680101077346 10 Q70HW3,P33527,O00400,Q5T3U5 4 +Toxic substance binding 0.957410071942446 1.878559357394808 0.060304685029584 1.0 0.344680101077346 2 P34913 1 +Arylesterase activity 0.9571223021582732 1.8773739213775087 0.0604668631725435 1.0 0.344680101077346 2 Q15165 1 +Phosphatidyl phospholipase b activity 0.9562589928057554 1.8738171301653832 0.0609556345057691 1.0 0.344680101077346 2 Q8IY17 1 +Serine hydrolase activity 0.5243306575982554 1.8711203926647304 0.0613283956176686 1.0 0.3448182886133982 20 Q9H3G5,Q4J6C6,P67812,Q9HB40,P42785,O75976 6 +L ornithine transmembrane transporter activity 0.9528057553956832 1.8595827825852136 0.062944577117556 1.0 0.3467661145819126 2 P30825 1 +Nucleotide transmembrane transporter activity 0.5698759631162358 1.857268802193779 0.0632729206501376 1.0 0.3467661145819126 14 Q99808,O00400,P41440 3 +Organophosphate ester transmembrane transporter activity 0.5698759631162358 1.857268802193779 0.0632729206501376 1.0 0.3467661145819126 14 Q99808,O00400,P41440 3 +Hormone binding 0.6597748734652258 1.8351973097598837 0.0664764596201132 1.0 0.3579501671852254 8 P30536,P42892,P04150 3 +Annealing activity 0.6438538728953371 1.828970172293929 0.0674040767463692 1.0 0.3601041745323254 9 P51114,Q15056,P23588,O94761 4 +Cargo receptor activity 0.7274783085278548 1.814970792664005 0.0695283980940257 1.0 0.3605176197468003 6 Q14108,Q8WTV0,O15260 3 +Metalloexopeptidase activity 0.5248016496310479 1.8084004290511757 0.0705442012147008 1.0 0.3630951533109602 19 P55786,O75844,Q9UIQ6,P09960,Q7Z2K6,O75976,Q9NZ08 7 +Epoxide hydrolase activity 0.7695167367197223 1.793509131433724 0.0728915518549722 1.0 0.3648457024142543 5 P07099,P34913 2 +Ether hydrolase activity 0.7695167367197223 1.793509131433724 0.0728915518549722 1.0 0.3648457024142543 5 P07099,P34913 2 +Purine nucleotide transmembrane transporter activity 0.5961135932093033 1.7897733901900734 0.0734903486291569 1.0 0.3648457024142543 11 Q99808,O00400 2 +Nucleobase containing compound transmembrane transporter activity 0.5431379761021293 1.7676383924075467 0.0771213753862163 1.0 0.3735983582723282 16 Q99808,P51991,O00400,P41440 4 +Porin activity 0.8156951058016121 1.7496583321457952 0.0801772877283402 1.0 0.3834423586601666 4 P21796,P45880 2 +Wide pore channel activity 0.8156951058016121 1.7496583321457952 0.0801772877283402 1.0 0.3834423586601666 4 P21796,P45880 2 +Hydrolase activity acting on carbon nitrogen but not peptide bonds 0.4618189580451619 1.74340715292752 0.0812625197362462 1.0 0.3856526360364227 27 Q9NTG7,P31939,Q8IXJ6 3 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines 0.6786854644907678 1.7334506000747634 0.0830156105915098 1.0 0.3914785436590232 7 P31939 1 +Palmitoyl protein hydrolase activity 0.7097958321316975 1.7324372986111638 0.0831957318751719 1.0 0.3914785436590232 6 Q9NUJ1,P50897,Q9UMR5 3 +Protein phosphatase regulator activity 0.51267447347107 1.7230900224991863 0.0848722468462406 1.0 0.3973951357349058 19 Q15257,Q86XL3,Q01105 3 +Abc type xenobiotic transporter activity 0.807613692764938 1.7158228157795594 0.0861944769209595 1.0 0.401999882956515 4 P08183 1 +Dicarboxylic acid transmembrane transporter activity 0.6737750007408865 1.709408712972658 0.0873752681093624 1.0 0.4042111859897621 7 Q9UJS0,Q9BQT8,Q9UBX3,P41440 4 +Intermediate filament binding 0.8039765770306874 1.700568348961795 0.089024071760871 1.0 0.4093831715536031 4 P48681,P08670 2 +Mrna 3 utr binding 0.3868104381062856 1.6963139010153274 0.0898264492898646 1.0 0.4093831715536031 48 P51116,O75150,Q8NC51,Q13148,P22626,Q5VTR2,Q14011,Q13151,Q71RC2,Q15717,Q06787,P35637,Q14103,Q01085,Q92804,Q92945,P51114,Q96EP5,Q9BWF3,O95453 20 +N6 methyladenosine containing rna binding 0.6708843353783265 1.6952333794684311 0.0900311571185219 1.0 0.4093831715536031 7 Q9Y5A9,Q7Z739,P07910,Q96MU7,P22626 5 +Inorganic molecular entity transmembrane transporter activity 0.3486494164568846 1.6950586373699057 0.0900642977417927 1.0 0.4093831715536031 81 P21796,O75964,P06576,P00846,Q93050,Q96ES6,Q9UBX3,P13073,Q13423,O00400,O43681,Q9C0H2,Q99797,Q15043,P45880,Q9Y277,Q9H2J7,Q9HD20,P98194,Q8N4V1,O75947,Q9Y5K8,Q5T3U5,P33527 24 +Metalloaminopeptidase activity 0.5786108307897386 1.6887917287261562 0.0912593494759579 1.0 0.4107745458654355 11 P55786,Q9UIQ6,P09960 3 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.938399539435806 1.676428761737583 0.0936542391415353 1.0 0.4134615394944314 3 P30519,Q9Y2Z9 2 +Phosphatase regulator activity 0.4875733361883703 1.6721176564284994 0.0945011235866111 1.0 0.4134615394944314 21 Q15257,Q86XL3,Q01105 3 +Hydrolase activity acting on ether bonds 0.6655492743952428 1.669028229697692 0.0951117853390184 1.0 0.4134615394944314 7 P07099,P34913 2 +Leucine zipper domain binding 0.9064748201438844 1.667618498162815 0.0953914837547866 1.0 0.4134615394944314 2 Q96IZ0 1 +Lrr domain binding 0.9064748201438844 1.667618498162815 0.0953914837547866 1.0 0.4134615394944314 2 Q96IZ0 1 +Procollagen proline dioxygenase activity 0.7953729260139788 1.6644206251956717 0.0960284011593555 1.0 0.4137016719847892 4 O15460,P13674 2 +Transition metal ion transmembrane transporter activity 0.7402073732718951 1.6632318885743294 0.0962660267304922 1.0 0.4137016719847892 5 P98194,Q15043,Q8N4V1,Q9HD20 4 +Carboxylic ester hydrolase activity 0.4158939643406238 1.6566463483751024 0.0975909959751186 1.0 0.4178207778751258 35 Q8IY17,O14734,Q9NUJ1,Q9HDC9,Q15165,Q8NCC3,P35790 7 +Single stranded rna binding 0.4062473951806395 1.6441379011694246 0.1001477205971415 1.0 0.4242436803847094 39 P51114,Q96DH6,Q15056,P23588,Q96EP5,Q71RC2,P31943,Q07666,O14979,P52597 10 +Mirna binding 0.5300795034268241 1.642297956439066 0.100528270423609 1.0 0.4242436803847094 15 Q15717,P67809,Q9BWF3,P09651,Q9UGR2,P43243,P98175,P22626 8 +Lysophospholipase activity 0.6904383640010122 1.6414304824190993 0.1007080866214729 1.0 0.4242436803847094 6 Q8NCC3,Q9NZC3,Q8IY17 3 +Sh3 domain binding 0.4628414648993928 1.6335019312363783 0.1023634748822521 1.0 0.4268234747698759 23 Q07960,Q96D71,Q07666,Q96T51,Q96PU8,P22681,Q9H2Y7,P46108,O75525,Q16204,P07948 11 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides 0.539324336556651 1.6324872559398678 0.1025768809949738 1.0 0.4268234747698759 13 Q8IXJ6 1 +Sterol transporter activity 0.591641931111752 1.6241452127902625 0.1043448204602024 1.0 0.426874706177584 10 P30536,Q9BZF3 2 +Carboxypeptidase activity 0.5674786107610427 1.6241298093017011 0.1043481071842342 1.0 0.426874706177584 11 Q9H3G5,O75976,P42785,Q9HB40 4 +Lamin binding 0.6181488405251385 1.6184779543366057 0.1055596341026356 1.0 0.4283579354889564 8 Q5JTV8,P42167,Q9ULX6,P42166,Q9UH99,Q5SNT2 6 +Efflux transmembrane transporter activity 0.922716801270042 1.6160877661781592 0.1060753388858002 1.0 0.4292065735263593 3 P08183 1 +Protein adp ribosylase activity 0.9210093919053496 1.6095087096560008 0.107505152085578 1.0 0.4312527590825482 3 Q9UGN5 1 +High density lipoprotein particle binding 0.9182275447306222 1.5987858392967318 0.1098681965683685 1.0 0.4345069920782937 3 Q8WTV0 1 +Protein lipid complex binding 0.9182275447306222 1.5987858392967318 0.1098681965683685 1.0 0.4345069920782937 3 Q8WTV0 1 +Steroid hormone receptor activity 0.8863309352517978 1.5837009948734886 0.1132617783150489 1.0 0.4382109186643569 2 O15173 1 +Lipid transporter activity 0.4555622108285063 1.5754215452162443 0.1151591744940745 1.0 0.4406995594199373 23 P33527,P08183,P30536,Q9BZF3 4 +Tropomyosin binding 0.9099021301093824 1.5666685432603755 0.1171921872130477 1.0 0.4458398426583336 3 P28289,Q9NYL9 2 +Deacetylase activity 0.607303184126174 1.561395761360912 0.1184304013555608 1.0 0.4463003345742828 8 Q8IXJ6 1 +Regulatory rna binding 0.4973335275895156 1.5587887475528812 0.1190463883452326 1.0 0.4463003345742828 18 Q15717,P67809,Q9BWF3,P09651,Q9UGR2,P43243,P98175,P22626 8 +Phosphatase activator activity 0.7150427105225214 1.550400616340169 0.1210453907212385 1.0 0.4464024415813897 5 Q15257 1 +Peptide binding 0.3383874283655238 1.550013913925809 0.1211381764474655 1.0 0.4464024415813897 71 P55786,P24390,P42892,Q15392,Q9H7Z7,O15212,P10321,Q9UIQ6,P04439,Q8WTV0,Q9BYT8,P40855,Q9NQX7,Q9NZ08,P21266,Q9UHB9,O00264 17 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.7664409818712887 1.5422710929657537 0.1230077304231684 1.0 0.4469792434977698 4 Q16850,Q9Y2Z9 2 +Thyroid hormone receptor binding 0.5761103766735908 1.5376185633982826 0.1241419058741784 1.0 0.4469792434977698 10 Q00403,Q9NPJ6,Q9Y2W1,Q96L73,Q9NVC6,O75376 6 +Folic acid binding 0.9023533844473396 1.537516330342464 0.1241669191543086 1.0 0.4469792434977698 3 P00374 1 +Adrenergic receptor binding 0.7103513163610815 1.529278195440447 0.1261954926956936 1.0 0.4469792434977698 5 P46934 1 +Transition metal ion binding 0.3107211633311355 1.5118157557522884 0.1305807400609251 1.0 0.4507139174245802 203 Q8IXJ6,P22830,P42892,Q5JRX3,P04150,O60888,Q13501,Q8NCC3,P55786,Q00403,Q6UW02,O95391,Q9NTG7,Q9BQG2,Q9Y3Z3,Q9HD42,P00813,Q05682,O75976,Q8N4Q0,O15460,Q9UIQ6,O43823,P13674,Q9BV57,Q16850,P09874,Q9UPP1,P36551,P09960,P05067,Q9NZ08,P05771 33 +Scaffold protein binding 0.4728931197194622 1.4972967342682868 0.1343160642622014 1.0 0.4575243064892506 20 P12956,P46108,Q9UQB8,P08670 4 +Rna strand annealing activity 0.7014014800887955 1.4889148864440875 0.1365097830050836 1.0 0.4595591135643078 5 P51114,Q15056,P23588 3 +Protein kinase a regulatory subunit binding 0.5925926865882312 1.4836208061222926 0.1379095464853632 1.0 0.4595591135643078 8 O43823 1 +Nucleotidase activity 0.5910184632132703 1.4752757826151055 0.1401384145067989 1.0 0.4632319533636383 8 Q9H857,Q969T7,P49902 3 +Mitochondrial ribosome binding 0.7469462342355422 1.4595289869517865 0.1444195684133027 1.0 0.4726308548539946 4 Q07021 1 +Kinesin binding 0.5391180589784025 1.4580469669536 0.144827597665974 1.0 0.4726308548539946 11 O43663,Q96EK5,Q86UP2,Q86Y91,Q92845,Q9H0B6 6 +Organic hydroxy compound transmembrane transporter activity 0.877555088882267 1.4415874927704353 0.1494187788788976 1.0 0.4853510218804099 3 Q14728 1 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.5117412023904869 1.4331985074162654 0.1518011161038934 1.0 0.4894320117753904 12 Q15392,Q9H7Z7,Q8N4Q0 3 +Cation channel activity 0.4631557921301506 1.4254594881693512 0.1540244226555227 1.0 0.4926463422328107 20 O75964,P00846 2 +Aldehyde dehydrogenase nad p plus activity 0.5815687472755671 1.4251012787819473 0.1541279270699793 1.0 0.4926463422328107 8 O94788 1 +Protein phosphatase activator activity 0.7360622165669353 1.4132156354195526 0.1575923306276982 1.0 0.4997898173724935 4 Q15257 1 +Procollagen proline 4 dioxygenase activity 0.8680715207709446 1.4048580002751705 0.1600635078561585 1.0 0.5019110895355733 3 O15460 1 +Peptidyl proline 4 dioxygenase activity 0.8680715207709446 1.4048580002751705 0.1600635078561585 1.0 0.5019110895355733 3 O15460 1 +Manganese ion transmembrane transporter activity 0.8647092688543434 1.3918331906344124 0.1639729166964159 1.0 0.5078807154313767 3 Q15043,Q9HD20 2 +Vitamin transmembrane transporter activity 0.5723141638723567 1.3758403641521173 0.1688710616966142 1.0 0.5173292918495842 8 P11166,P33527,P41440 3 +Aminopeptidase activity 0.4932141558987103 1.3704352516847436 0.1705510742479394 1.0 0.5210732529443077 14 P55786,Q9UIQ6,P09960 3 +Proton transmembrane transporter activity 0.3826334823108648 1.3635014910459502 0.1727245148654121 1.0 0.525683306112124 37 O75964,Q13423,O00400,P06576,P00846,Q96ES6,Q93050,O75947,Q9Y5K8,P13073 10 +Dioxygenase activity 0.4458279473598725 1.3565651731436417 0.1749194139944749 1.0 0.5295261217858299 21 O15460,P13674,Q9BV57,Q9UPP1 4 +Pre mrna binding 0.4675616764287785 1.3502331567165082 0.1769412057446109 1.0 0.5315139217876865 18 Q15637,Q9BWF3,O95391,P62995,Q13148,Q01130,P22626 7 +Carbohydrate derivative transmembrane transporter activity 0.5207689298519063 1.3497460739331624 0.1770974478512321 1.0 0.5315139217876865 11 Q99808,O00400 2 +Modified amino acid transmembrane transporter activity 0.6701387707650559 1.3473471217827326 0.1778684623645117 1.0 0.5320851438254623 5 P33527 1 +Neurotransmitter transmembrane transporter activity 0.8287769784172647 1.3433552184727473 0.1791569799987451 1.0 0.5327307760625587 2 Q99808 1 +Abc type transporter activity 0.5539938649980727 1.343182579952422 0.1792128609138867 1.0 0.5327307760625587 9 P08183,P33527 2 +Cysteine type endopeptidase inhibitor activity involved in apoptotic process 0.6663018090964969 1.32992536691242 0.1835428625882196 1.0 0.5398319487888812 5 P51812 1 +Cysteine type endopeptidase inhibitor activity 0.5170945286526685 1.3279982328447342 0.184178690706414 1.0 0.5405663878175674 11 P51812 1 +Intramembrane lipid transporter activity 0.6649734737570308 1.3238923715102997 0.1855387921043527 1.0 0.5422845698248306 5 P08183 1 +Protein prenyltransferase activity 0.6202684951105141 1.3069127300631802 0.1912423521487776 1.0 0.5475241165813673 6 P49354,Q7Z6K3,Q92696,P49356 4 +Protein kinase a binding 0.4598911309987777 1.2961834351721109 0.194912295077863 1.0 0.5546284819288785 18 O43823 1 +Amide binding 0.3138158185005931 1.2909082539600785 0.1967354929534783 1.0 0.5575499800301006 104 P21796,Q96AY3,P42892,Q9UM22,Q9Y680,O15212,P26885,Q8WTV0,P55786,P00374,O75521,Q02252,P21266,Q15392,Q9H7Z7,P45880,Q9UIQ6,P40855,Q9NZ08,O00264 20 +Glycosyltransferase activity 0.3475178697455185 1.2784242448238574 0.2010998799384651 1.0 0.5676206288585709 51 P09874,Q13126,Q8IXJ6,Q9NTG7,Q9UGN5 5 +H3 histone acetyltransferase activity 0.8112230215827325 1.270164922828413 0.2040258895240077 1.0 0.5724173253178573 2 Q92830 1 +O acyltransferase activity 0.4727210793192919 1.267070463642799 0.2051300956265069 1.0 0.5732178320900394 15 Q6UWP7,P35610,O15228,P23786,Q8NCC3 5 +Histone methyltransferase activity h4 k20 specific 0.8094964028776964 1.2629758943818812 0.2065978429173252 1.0 0.5749099531549037 2 O96028 1 +2 oxoglutarate dependent dioxygenase activity 0.4598493023342015 1.2519669157869495 0.2105819196149756 1.0 0.5780680146293449 17 O15460,Q9UPP1 2 +Peptidyl proline dioxygenase activity 0.6454793684275794 1.2352878371495968 0.2167233987534844 1.0 0.5838715923507471 5 O15460,P13674 2 +Inorganic anion transmembrane transporter activity 0.4133053282084679 1.2345841170039444 0.2169853231714764 1.0 0.5838715923507471 23 P21796,Q9C0H2,Q15043,P45880,O43681,Q9Y277,Q5T3U5,P33527 8 +Spectrin binding 0.6037260144839303 1.227366797987701 0.2196847596345259 1.0 0.5880662781803754 6 P35611 1 +Proline rich region binding 0.6034006986717375 1.2258014501608578 0.2202734013608007 1.0 0.5885167211929792 6 Q9UQB8,P46934 2 +Intraciliary transport particle b binding 0.7936690647481999 1.1971925807753825 0.2312315009963503 1.0 0.6122939155973549 2 Q92845 1 +Oxidoreductase activity acting on the aldehyde or oxo group of donors 0.4245075784367043 1.193672145370744 0.232606240523038 1.0 0.6132744571228874 21 P30837,O94788 2 +Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor 0.4245075784367043 1.193672145370744 0.232606240523038 1.0 0.6132744571228874 21 P30837,O94788 2 +D loop dna binding 0.8111686816350001 1.1846465123079062 0.236157238717297 1.0 0.618314860172932 3 Q96B01,Q14191 2 +Heme transmembrane transporter activity 0.8109369207915127 1.1837522863279246 0.2365111347118782 1.0 0.618314860172932 3 Q9Y5Y0 1 +Iron ion transmembrane transporter activity 0.7899280575539552 1.1816799984509343 0.2373326976206533 1.0 0.618314860172932 2 Q15043 1 +Ubiquitin like protein binding 0.3637015088336379 1.1722169137838987 0.2411099794383839 1.0 0.6216463558264044 37 Q9Y679,Q8NC51,Q99816,Q8IXJ6,Q92564,Q9UNZ2,Q9H1I8,Q96EP0,Q9BTE7,P54725,Q13501,Q8IZL8,P37198,P46934 14 +Single stranded dna binding 0.3204900066952012 1.1603465488342355 0.2459077396069477 1.0 0.6293799551183307 63 P53999,P33991,P67809,Q04837,Q96B01,Q96SB8,Q9H1E3,Q14566,O94761,Q9NYB0,Q9P2K5,Q9NS91,Q9Y3Z3,Q96AE4,Q96I24,Q00577,P22626 17 +Sh2 domain binding 0.5079218826135946 1.1531392353800256 0.2488532396241798 1.0 0.63575645159462 10 Q07666,P46108,Q8NEM2,P37198 4 +Single stranded dna exodeoxyribonuclease activity 0.6736534053348715 1.1470432148319776 0.251363760929957 1.0 0.6398333689269249 4 Q9UQ84,Q9NVH0 2 +Sulfotransferase activity 0.7810071942446026 1.1447565849619958 0.252310004268947 1.0 0.6399166774937062 2 Q8NCH0 1 +Scavenger receptor activity 0.7998562164720087 1.141047241858545 0.2538502642652647 1.0 0.6426588968740878 3 Q8WTV0 1 +Structural constituent of eye lens 0.7962003454231349 1.1269809790512717 0.2597505231294965 1.0 0.646239861966352 3 P36551,P08670 2 +Transferase activity transferring alkyl or aryl other than methyl groups 0.3831579239888703 1.126198012640634 0.2600817145457066 1.0 0.646239861966352 29 P37268,O00116,Q9Y5Z9,P49366,P49356,Q5T2R2,Q9Y2Q3,P21266,O95749 9 +Four way junction helicase activity 0.7957722808500893 1.1253348122837767 0.2604471831857293 1.0 0.646239861966352 3 Q14191 1 +Bubble dna binding 0.7957722808500893 1.1253348122837767 0.2604471831857293 1.0 0.646239861966352 3 Q14191 1 +Rna polymerase binding 0.3823195545119345 1.1187095654395187 0.263264063089903 1.0 0.6486144822123378 29 Q00403,Q8N163,P46934 3 +Histone deacetylase binding 0.3561343916163544 1.111498770115585 0.2663537191458647 1.0 0.6486144822123378 38 P09874,Q8IXJ6,Q9ULX6,O43823,Q92830 5 +Keratin filament binding 0.7921473546706178 1.111402274445607 0.2663952337657815 1.0 0.6486144822123378 3 P08670 1 +Acid amino acid ligase activity 0.5516276760468096 1.100061217180408 0.2713054501987659 1.0 0.6571328433737224 7 Q8N2G8 1 +Solute proton symporter activity 0.789089052872366 1.09965849466184 0.2714809452040709 1.0 0.6571328433737224 3 O00400 1 +Pyruvate dehydrogenase acetyl transferring kinase activity 0.7689208633093507 1.0949103435532623 0.2735559170653947 1.0 0.6603073860199182 2 Q15118 1 +Growth factor activity 0.5738249868486588 1.0835076755593265 0.2785831458073706 1.0 0.6689818252664133 6 Q9Y3E1,P51858 2 +Nuclear receptor coactivator activity 0.4005540751216916 1.0670995759508466 0.2859268733112425 1.0 0.6767938850839526 22 Q9NPJ6,Q9Y2W1,Q99816,Q8N163,P17096,Q96PK6,Q86X55,P05771 8 +Folic acid transmembrane transporter activity 0.7582733812949621 1.051202597295115 0.2931655505449333 1.0 0.6874904032879509 2 P41440 1 +Demethylase activity 0.4699898708540544 1.0485115486662882 0.29440298430133 1.0 0.6880871085506879 11 Q9UPP1 1 +Phosphatidylserine binding 0.4996503126478793 1.0443534946750197 0.2963218713942253 1.0 0.6902672544956995 9 Q14108,Q8WTV0 2 +Phosphatidylinositol 3 kinase binding 0.6483828503916171 1.0396639194892376 0.2984960689416986 1.0 0.6941769045155783 4 P22681,P0DP25 2 +Ephrin receptor binding 0.4983270903243125 1.0370872606539585 0.2996951917189889 1.0 0.6958097320175531 9 P22681,P46108,P18031,P07948 4 +Phospholipase d activity 0.7505035971223002 1.0194492667257051 0.307989727021041 1.0 0.7016727033833016 2 P09601 1 +5 3 exodeoxyribonuclease activity 0.7505035971223003 1.0194492667257051 0.307989727021041 1.0 0.7016727033833016 2 Q9UQ84 1 +Acid phosphatase activity 0.7678787213123592 1.018537724978359 0.308422482203734 1.0 0.7016727033833016 3 Q9NPH0 1 +Collagen binding 0.5050753676735585 1.0163964171158382 0.3094406511127965 1.0 0.7016727033833016 8 Q92791,O75718 2 +G protein alpha subunit binding 0.6426708327887602 1.0154908338110784 0.3098719137170254 1.0 0.7016727033833016 4 Q02818,P80303 2 +C4 dicarboxylate transmembrane transporter activity 0.5934073766745646 0.9990767799423528 0.3177574985555478 1.0 0.7090692125465632 5 Q9UJS0,O75746,Q9UBX3 3 +Histone lysine n methyltransferase activity 0.4318364225899583 0.9973911865823868 0.3185746676369916 1.0 0.7090692125465632 15 O15047,Q14166,O96028,Q9H7B4,Q03164,Q96L73,Q8WTS6 7 +Lysine n methyltransferase activity 0.4318364225899583 0.9973911865823868 0.3185746676369916 1.0 0.7090692125465632 15 O15047,Q14166,O96028,Q9H7B4,Q03164,Q96L73,Q8WTS6 7 +Acetylgalactosaminyltransferase activity 0.6374586961980837 0.9934750599733848 0.320478498586537 1.0 0.7099207247170124 4 Q8N6G5 1 +Retinoid x receptor binding 0.7392805755395663 0.9738263729468356 0.3301427560043104 1.0 0.7177016434876313 2 Q96L73 1 +Ubiquitin binding 0.3584718583346215 0.9657729714293712 0.3341577961064859 1.0 0.7230616917296449 31 Q9Y679,Q99816,Q8IXJ6,Q9UNZ2,Q9H1I8,Q96EP0,Q13501,P37198,P46934 9 +Cis regulatory region sequence specific dna binding 0.3086443626655687 0.9590446266628466 0.3375362640137576 1.0 0.7278814350033287 61 P53999,Q13148,Q9Y2W1,O95785,Q9H7B4,P50750,P04150,O00330,Q9NXV6,P38159,Q96L73,P51858,Q96EB6,Q15424,P05067,Q8ND82 16 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.5838950477183149 0.9562312506797472 0.3389554147064051 1.0 0.7278814350033287 5 Q15067,P36551 2 +Transcription coregulator activity 0.2702273611813111 0.9477823577477004 0.3432402636964526 1.0 0.7346362548080158 158 P53999,Q9Y2W1,Q8N163,P38398,Q86U70,Q96JN0,Q96L73,P51858,P61457,Q96EB6,Q92905,O60828,Q5VTR2,Q9H1E3,Q92841,Q7Z4V5,Q07021,Q96PK6,Q86UE4,O14981,Q9NPJ6,O75475,Q01844,O75381,Q9Y3E1,P35637,Q01130,Q92804,Q9UER7,Q86X55,Q96IZ0,Q92830,Q15637,O00233,Q9UPP1,O60869,Q969G3,Q9NPI1,Q9HCD5,Q9NYF8,P52948,P05771 42 +Ubiquitin conjugating enzyme binding 0.4915586589335552 0.9444479123473698 0.344940807429984 1.0 0.7346362548080158 8 Q9Y679,O75150,Q92564,Q9BTE7,Q9UBW7 5 +Phosphatidylcholine binding 0.4891213672371683 0.9315126633978724 0.3515884371683504 1.0 0.7381040484544069 8 P21796,P45880 2 +Syntaxin binding 0.3738736894167065 0.9301908027431866 0.3522723030186423 1.0 0.738295245847454 24 O75150,Q5SQN1,Q9UNK0,Q6ZWJ1,O14795,O60499,Q9H270,Q08379,Q9P253,O95721 10 +Vitamin d receptor binding 0.4885698778574561 0.9285876963525652 0.3531028005564032 1.0 0.7389296274722936 8 Q9NPJ6,Q9NVC6,Q9Y2W1,Q13573 4 +Aspartic endopeptidase activity intramembrane cleaving 0.7429156223791054 0.924017599907431 0.3554771525002369 1.0 0.7393202094151808 3 Q8TCT9 1 +Abc type glutathione s conjugate transporter activity 0.7419854709330536 0.9205204639416724 0.3573008441498269 1.0 0.7393202094151808 3 P33527 1 +Rna polymerase core enzyme binding 0.3906117567166757 0.8869832140955322 0.3750879378794449 1.0 0.759541473733017 20 Q9H7B4,Q8N163,Q00403 3 +Secondary active transmembrane transporter activity 0.3694693267578849 0.8793593883468344 0.3792064446006575 1.0 0.7616772201447929 23 O00400,P41440,Q15043,Q96ES6,P53985,Q9UBX3,Q9H2J7 7 +Pre mrna intronic binding 0.5601096373300242 0.8499291176097685 0.3953644958989106 1.0 0.7828730467684532 5 P22626,Q13148 2 +Succinate transmembrane transporter activity 0.7067625899280552 0.8436753038116621 0.3988508714746885 1.0 0.7838754955778027 2 Q9UBX3 1 +Sulfate transmembrane transporter activity 0.7067625899280552 0.8436753038116621 0.3988508714746885 1.0 0.7838754955778027 2 Q9UBX3 1 +Acylglycerol o acyltransferase activity 0.4614950982597794 0.8362049872646041 0.4030395932111208 1.0 0.7859955847590469 9 Q6UWP7 1 +Poly a binding 0.4337138352237677 0.8349370325447231 0.4037531625370141 1.0 0.7859955847590469 11 Q07666,O14979,Q71RC2 3 +Flavin adenine dinucleotide binding 0.3530463476137326 0.833626117033619 0.4044917036623763 1.0 0.7859955847590469 28 O00116,Q16134,Q15067,Q15392,O95831,Q9Y2Z9 6 +Glycolipid binding 0.4508298018215595 0.831672260330066 0.4055939624072362 1.0 0.7859955847590469 10 Q9UM22 1 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.4974635401596138 0.8298115221895408 0.4066453552651508 1.0 0.7859955847590469 7 Q15418,P51812 2 +Amide transmembrane transporter activity 0.4950228655668829 0.8177963236681246 0.4134734976275549 1.0 0.7891139162778893 7 P33527,O00400 2 +3 5 dna helicase activity 0.448075542058676 0.8163765471200309 0.4142848060458919 1.0 0.7891139162778893 10 Q14566,Q14191 2 +Protein methyltransferase activity 0.341724388976308 0.8119064698238367 0.4168453017378446 1.0 0.7911235151977638 31 O15047,Q14166,O96028,Q86X55,Q9H7B4,Q03164,O60725,Q52LJ0,Q6P2P2,Q96L73,Q8WTS6 11 +G rich strand telomeric dna binding 0.5149565042330083 0.8031692606815763 0.4218769099518833 1.0 0.7911235151977638 6 Q9NYB0,P22626 2 +Unmethylated cpg binding 0.7041699633650582 0.7803119432632277 0.4352072845678389 1.0 0.8023253068673194 3 Q03164 1 +Phosphatidylinositol phosphate kinase activity 0.68892086330935 0.7739053208451296 0.4389867828269631 1.0 0.8065373962700111 2 Q8TBX8 1 +Phospholipid scramblase activity 0.6883453237410047 0.7716778133839947 0.4403052744730806 1.0 0.8071743632540404 2 Q7Z3C6 1 +Fatty acid derivative binding 0.4213869925027211 0.7634458618279097 0.4451975376496562 1.0 0.8094500684539203 11 O75521,Q02252,Q5T8D3 3 +Acyl coa binding 0.4213869925027211 0.7634458618279097 0.4451975376496562 1.0 0.8094500684539203 11 O75521,Q02252,Q5T8D3 3 +Protein geranylgeranyltransferase activity 0.5788596894376046 0.7502709085004885 0.4530915599499141 1.0 0.8206056713193788 4 P49354,Q92696 2 +Mrna 3 utr au rich region binding 0.4009013753941122 0.7461472733553094 0.4555784551000146 1.0 0.8209230562316358 12 Q15717,Q01085,Q92945,Q13151 4 +Voltage gated anion channel activity 0.4791270232499381 0.7401072079898299 0.4592349453995381 1.0 0.8253259609234319 7 P21796,P45880 2 +Dna secondary structure binding 0.3866954460010556 0.7249710859939797 0.468469768842463 1.0 0.8344245246557866 16 P43246,Q96B01,Q03164,O94761,Q14103,Q9NS91,Q9HAW4,Q14191 8 +Peptide lysine n acetyltransferase activity 0.3937963952183297 0.7160781728921515 0.4739430805866371 1.0 0.8406537174372937 13 Q00403,Q92830,Q86UY6 3 +Lysine acetylated histone binding 0.3921947896683885 0.7062857178284118 0.4800104733874475 1.0 0.8418231939848777 13 O60885,Q9NPI1,Q03164,O15164,O95619,Q86X55,Q9ULU4 7 +Signaling receptor regulator activity 0.3654471238538105 0.7035621638087671 0.4817054810525092 1.0 0.8418231939848777 20 Q9Y3E1,P05067,P51858 3 +Mrna binding 0.2638722957815333 0.7018995770829521 0.4827417926920905 1.0 0.8418231939848777 178 P51116,O60506,O75150,Q07955,Q9Y5A9,O43390,P33240,P19338,Q9P2K5,Q13148,Q86V81,P22626,Q5VTR2,Q14011,Q99729,P00374,Q13151,Q96PU8,Q71RC2,P62995,Q07021,P38159,Q53F19,Q96PK6,P67809,P35637,O60508,P52272,Q96AE4,O75525,Q92804,Q01085,Q92945,P51114,P52756,Q96EP5,Q8N684,O95453,P51991,Q96I24,Q07666,P61978 42 +Passive transmembrane transporter activity 0.3161977854488252 0.684828303155083 0.4934522729894628 1.0 0.8519009744847099 36 P21796,O75964,P06576,P00846,P45880 5 +Oxidoreductase activity acting on the ch ch group of donors 0.3377596043299792 0.6828350708779906 0.4947110658971922 1.0 0.8519009744847099 27 Q15392,Q15067,Q9H7Z7,Q6NUM9,Q9BY49,Q8N4Q0 6 +Thiolester hydrolase activity 0.3792691427094523 0.6768519072242392 0.4984999203852509 1.0 0.8520171791471578 16 Q9NUJ1,P50897,Q9UMR5 3 +Endopeptidase activator activity 0.5605555288779296 0.6767547678895353 0.498561561164748 1.0 0.8520171791471578 4 P61289,Q9UL46 2 +Structural constituent of postsynapse 0.5548778302179155 0.6542823491835278 0.5129299154792608 1.0 0.8641418551997174 4 Q16352 1 +Glutamate receptor binding 0.3990246819894606 0.6361673050847295 0.5246673807595938 1.0 0.8750486069698024 11 P41440,P0DP25 2 +Structural constituent of synapse 0.5105924590426253 0.6349492900227343 0.5254614885832463 1.0 0.8750486069698024 5 Q16352,P12814,P56545 3 +Transcription regulator inhibitor activity 0.5490832472791413 0.6315281169018302 0.5276952708612135 1.0 0.8750486069698024 4 Q9UER7 1 +Single stranded telomeric dna binding 0.4561074061186556 0.6298208043223943 0.5288118324798399 1.0 0.8750486069698024 7 Q9NYB0,P22626 2 +Basal transcription machinery binding 0.3240964083652451 0.6279172158865745 0.5300581724040074 1.0 0.8750486069698024 30 Q00403,O60869,Q8N163 3 +Active ion transmembrane transporter activity 0.2936887424682956 0.6260540172722927 0.5312795113745228 1.0 0.8750486069698024 47 O00400,P06576,P41440,Q15043,P35670,Q96ES6,P16615,P33527,Q9UI12,Q9HD20,Q9H2J7,Q9Y5K8,Q5T3U5,P98194,P13073,P36543,O14548,P51790 18 +N acyltransferase activity 0.3317567127868726 0.6170564068550745 0.5371975209345092 1.0 0.8785024982893547 26 Q00403,Q969G3,P27544,O60318,Q86UY6,Q96G23,Q96EB6,Q92830 8 +Nitric oxide synthase regulator activity 0.5055028047946724 0.6135531199878339 0.539510670366377 1.0 0.8785024982893547 5 P31749 1 +Protein serine kinase activity 0.2724673664696582 0.6106522076433619 0.5414298520363401 1.0 0.8785024982893547 67 P31751,P51812,Q13546,O14976,Q15418,P50750,Q9BVS4,Q7KZI7,P49761,P31749,P05771 11 +L ascorbic acid binding 0.4265647528344153 0.6075085613208763 0.5435134627449552 1.0 0.8785024982893547 8 O15460,P13674 2 +Cytokine binding 0.5036020086713422 0.6056045579934721 0.5447773749127418 1.0 0.8785024982893547 5 O00165 1 +Threonine type endopeptidase activity 0.4260511266414398 0.6049443446645706 0.5452159772055514 1.0 0.8785024982893547 8 P20618,P28072,P49721,P28070 4 +Lys63 specific deubiquitinase activity 0.6543927519373913 0.6038752986797749 0.5459265525083847 1.0 0.8785024982893547 3 Q01804 1 +Rna polymerase ii general transcription initiation factor activity 0.5000197345150034 0.5906894287662121 0.5547285322909188 1.0 0.8851153123884928 5 Q00403 1 +R smad binding 0.4991645419314823 0.5871415981553736 0.5571086117777266 1.0 0.8851153123884928 5 P09874 1 +Sequence specific single stranded dna binding 0.4223186662067489 0.5863763303700031 0.5576226468047505 1.0 0.8851153123884928 8 Q9NYB0,P22626 2 +Triglyceride lipase activity 0.6359712230215797 0.5766128177263059 0.5642010384612317 1.0 0.8895061417181582 2 Q8NCG7 1 +Histone methyltransferase activity h3 k36 specific 0.6458291581542874 0.5747730884988895 0.5654447695031757 1.0 0.890464203942009 3 O96028 1 +Ap 2 adaptor complex binding 0.6333812949640256 0.5674282558801973 0.5704232571757786 1.0 0.8905816148852285 2 Q2M2I8 1 +Protein kinase c binding 0.3583482674932263 0.5649492677778785 0.5721082715088222 1.0 0.8905816148852285 17 Q01130,Q07021,P05771,P29966 4 +Ionotropic glutamate receptor binding 0.4625046455792327 0.5637092622478644 0.5729520128352075 1.0 0.8905816148852285 6 P41440 1 +G protein beta gamma subunit complex binding 0.5280673365648161 0.5507248982180488 0.5818222739433545 1.0 0.8905816148852285 4 P08754,P41208 2 +S methyltransferase activity 0.6368634392734418 0.544777643356133 0.5859064566390719 1.0 0.8905816148852285 3 Q03164 1 +Telomeric dna binding 0.3375779946691935 0.5416682904158214 0.5880470379104332 1.0 0.8905816148852285 21 Q14191,Q9UPR3,Q96DT7,P09651,P19338,P12956,Q9NYB0,Q00577,P22626 9 +General transcription initiation factor activity 0.456124390149532 0.5357680891449448 0.5921188390330849 1.0 0.892261191294946 6 Q00403 1 +Tbp class protein binding 0.4039578744333535 0.5349038256355797 0.5927163627887855 1.0 0.892261191294946 9 Q00403 1 +Hsp70 protein binding 0.348655963309505 0.5260269896886155 0.5988694546358893 1.0 0.8950834242745792 18 P46379,O75937,Q8IXB1,Q9NUL3,Q96EY1,P37198 6 +Protein serine threonine kinase activity 0.2675226764229385 0.5213247565227945 0.60214055786262 1.0 0.8967401576396147 79 Q13464,P50750,Q13501,Q2M2I8,Q15120,P33981,Q96KB5,P49761,P31749,P31751,Q9P289,P51812,O14976,Q15418,Q8IV63,Q9BVS4,Q7KZI7,Q9NYV4,Q13546,O60885,Q86UE8,O60566,P05771 23 +Transcription regulator activity 0.2594646604249759 0.5177855759028546 0.6046078832332022 1.0 0.898062770949501 196 P53999,Q9Y2W1,Q8N163,P04150,P38398,Q86U70,Q96JN0,Q96L73,P51858,P61457,Q96EB6,Q92905,Q00577,O60828,Q5VTR2,Q96DT7,Q9H1E3,Q92841,Q7Z4V5,Q07021,Q96PK6,Q86UE4,O14981,Q8ND82,Q00059,Q9NPJ6,O75475,Q01844,O75381,Q9Y3E1,P35637,Q9NXV6,Q01130,Q92804,Q9UER7,Q86X55,Q96IZ0,Q92830,O00233,Q9UPP1,O60869,Q969G3,Q9NPI1,O95785,Q8IZL8,Q9HCD5,Q9NYF8,P05771 48 +Phosphatidic acid binding 0.6285167070404466 0.5173183763413318 0.6049339281357293 1.0 0.898062770949501 3 O60313 1 +Plus end directed microtubule motor activity 0.4075191216530134 0.5140014212035589 0.6072509970320767 1.0 0.898062770949501 8 Q86Y91 1 +Phospholipid binding 0.267315788217337 0.5090938724246039 0.6106864266747047 1.0 0.898062770949501 93 P21796,P53367,Q9UM22,P45880,Q8WTV0,Q8NCC3,P31749,P37198 8 +Histone binding 0.2663922798751961 0.4990493929937468 0.6177445879814591 1.0 0.9018329291384328 95 P16104,Q03164,O60318,P39687,Q96EB6,P06748,Q5VTR2,Q8WXX5,Q9NWS0,Q7Z4V5,Q8NB78,Q01105,P55209,Q15020,Q06787,Q12888,Q14149,O43159,O15164,Q9BTT0,Q9UER7,Q86X55,Q9Y4E8,O95619,Q9ULU4,P45973,Q96T23,Q14166,Q9UPP1,P29375,Q13185,Q6PL18,O60885,Q14781,Q9NPI1,Q9H2V7,Q99733,Q92922,P49321,P05771 40 +Potassium channel regulator activity 0.4271930727612607 0.4965583658345396 0.6195005190521505 1.0 0.9018329291384328 7 P31749 1 +Histone methyltransferase activity 0.3253921106629678 0.4920163490557678 0.6227077859466719 1.0 0.903030434965174 22 O15047,Q14166,O96028,Q9H7B4,Q03164,Q96L73,Q86X55,Q8WTS6 8 +Hexosaminidase activity 0.4749099796870056 0.4888151950443146 0.6249725393531764 1.0 0.9039162854335934 5 P06865,O60502 2 +Threonine type peptidase activity 0.3936546941760225 0.4838774619372662 0.6284728364048835 1.0 0.9039162854335934 9 P20618,P28072,P49721,P28070 4 +Card domain binding 0.6083453237410041 0.4814085625233354 0.6302261522852131 1.0 0.9039162854335934 2 Q7Z434 1 +Metallocarboxypeptidase activity 0.6171553367487264 0.4807155324096591 0.6307186903455717 1.0 0.9039162854335934 3 O75976 1 +Heparin binding 0.3553138987830634 0.4802767896055063 0.6310305906921101 1.0 0.9039162854335934 12 P05067 1 +Atpase coupled transmembrane transporter activity 0.3144882463734371 0.4796868344804205 0.6314500908243246 1.0 0.9039162854335934 26 P08183,P06576,P35670,P16615,Q9HD20,Q9Y5K8,Q5T3U5,O75027,P98194,P36543,P33527 11 +Intramolecular oxidoreductase activity transposing c c bonds 0.3995722218274664 0.4760667010042164 0.6340268591335594 1.0 0.9048293606391266 8 O75521,Q13011 2 +Poly pyrimidine tract binding 0.3466790865574363 0.4729881776069864 0.6362216137793686 1.0 0.905193352938126 16 Q96DH6,Q07666,P31943 3 +Transferrin receptor binding 0.6091585548222487 0.4555236228174589 0.6487325767012795 1.0 0.9136936617239816 3 Q13596 1 +Isomerase activity 0.2629294509830736 0.4551089873850211 0.6490308325977237 1.0 0.9136936617239816 80 Q96AY3,Q13011,O95302,Q9H7Z7,Q9Y680,Q15257,Q9NWM8 7 +Protein kinase b binding 0.6085204375359695 0.4535346622551321 0.6501637896743686 1.0 0.9136936617239816 3 Q13243,Q9UKG1 2 +Atpase coupled cation transmembrane transporter activity 0.3427380829950796 0.4493837328394414 0.6531548640235896 1.0 0.9144168096330254 16 P06576,P35670,P16615,Q9HD20,Q9Y5K8,P98194,P36543 7 +Hydrolase activity acting on ester bonds 0.2517320043543162 0.4425451730590084 0.65809474921695 1.0 0.918576918149282 182 Q9NPH0,Q9UNK9,O14734,Q15257,Q9H6V9,Q9HDC9,Q8NCC3,Q969T7,P34913,Q10713,P49902,O43681,Q9BQG2,Q9NUJ1,Q9UQ84,Q8NHP8,P09601,P35790,Q8IY17,Q9UMR5,Q15165,Q5RKV6,P50897 23 +Exogenous protein binding 0.3422425097338415 0.4230155080499444 0.6722839463882839 1.0 0.9300036920019 14 Q14108,Q8WTV0 2 +Oxidoreductase activity 0.2639414630836659 0.4185949251909178 0.6755121990462563 1.0 0.9300036920019 237 P30519,O43676,Q16134,Q9UHG3,Q9P0J0,Q9NRG7,O95831,P61457,P13073,Q9BY49,Q9H9P8,Q9Y2Z9,O94788,Q13423,P00374,O00116,Q8NBX0,Q6UW02,Q9BU89,Q15067,P30837,Q02252,O43169,Q06136,P00367,Q8N4Q0,O75845,Q96LJ7,Q15392,P48735,Q9H7Z7,O15460,P09601,P13674,Q6NUM9,O96000,Q9BV57,Q16850,O75489,Q9UPP1,P36551,O95169,P14406 43 +Nuclear localization sequence binding 0.3418128347417038 0.4125811746990874 0.6799134961021722 1.0 0.9313883508248936 13 P49790,Q9BVL2,Q14978,P35658,P52292,P52948 6 +L aspartate transmembrane transporter activity 0.5941344626329905 0.4095718650330057 0.6821200392112203 1.0 0.9325859911090904 3 Q9UJS0 1 +Acidic amino acid transmembrane transporter activity 0.5941344626329905 0.4095718650330057 0.6821200392112203 1.0 0.9325859911090904 3 Q9UJS0 1 +Quaternary ammonium group binding 0.3564459501086798 0.4076809417630112 0.6835079310969252 1.0 0.9335718083275076 11 P21796,P45880 2 +Oxidized dna binding 0.4046550088387588 0.3982927708949518 0.6904143886187091 1.0 0.9386352011366212 7 O94761,Q14191 2 +Snap receptor activity 0.3351246700437432 0.3928297403901267 0.6944452371933147 1.0 0.9420768721614736 15 Q9P2W9,O95721,O60499,Q5SQN1 4 +Chromatin binding 0.2526327257546363 0.3908110810822554 0.6959368835816924 1.0 0.9428326807787242 195 P18615,Q8IXJ6,P50750,O60318,Q86U70,Q9UK61,Q96EB6,Q5VTR2,Q00403,Q04837,Q9Y619,Q9H1E3,P82970,Q9UGN5,P38159,Q01105,P37198,P55209,P67809,P23246,Q9UQ84,Q5W0B1,P35637,O95983,Q9Y2U8,Q8N7H5,Q15233,Q92830,P45973,O96028,Q6PL18,Q9UPP1,Q969G3,Q99733,Q8IZL8,Q9HCD5,Q14191,P82979,P05771 39 +Non membrane spanning protein tyrosine kinase activity 0.400576368876073 0.3811557703328445 0.7030876664295795 1.0 0.9435358448874068 7 Q05655,P41240,Q05397,Q9UIG0,P07947,P07948 6 +Poly purine tract binding 0.3321703170672535 0.3762651005857461 0.7067198218559323 1.0 0.9435358448874068 15 Q96EP5,Q07666,O14979,Q71RC2 4 +Transcription coactivator activity 0.2579315849516109 0.3745740458516808 0.7079772783865272 1.0 0.9435358448874068 94 P53999,Q9Y2W1,Q8N163,P38398,P61457,Q96EB6,Q92905,O60828,Q5VTR2,Q9H1E3,Q92841,Q96PK6,Q86UE4,Q9NPJ6,P35637,Q9UER7,Q86X55,Q92830,O00233,O60869,Q969G3,Q9NPI1,P52948,P05771 24 +Protein serine threonine tyrosine kinase activity 0.255334681042642 0.3741418871230321 0.7082987565579446 1.0 0.9435358448874068 74 P51812,Q15418,P49761,P31749,P05771 5 +Tau protein kinase activity 0.3702422145328582 0.372914862529151 0.7092118099497398 1.0 0.9435358448874068 9 Q9UL54,Q13464,P27448,P49840,Q00535,O75116,Q7L7X3,Q7KZI7 8 +Nuclear receptor binding 0.2699286773946292 0.3718674903276308 0.7099915110604706 1.0 0.9435358448874068 48 Q00403,Q9NPJ6,P09874,Q969G3,Q96JN0,P05771 6 +Transcription elongation regulator activity 0.5729496402877663 0.3696903256233327 0.7116132409517548 1.0 0.9435358448874068 2 Q15061 1 +Active transmembrane transporter activity 0.2566231494674641 0.3666307290706347 0.713894483530011 1.0 0.9435358448874068 81 P08183,O43676,P06576,P41440,O95169,O00400,Q15043,Q96ES6,P53985,Q9P0J0,Q9HD20,P98194,P13073,O96000,P33527 15 +1 phosphatidylinositol 4 kinase activity 0.5786801543001485 0.3643365221091328 0.7156067305424996 1.0 0.9435358448874068 3 Q9BTU6 1 +Sequence specific dna binding 0.2432545855865751 0.3609528947101428 0.7181346610070223 1.0 0.9435358448874068 168 P53999,Q14191,Q9Y2W1,Q9H7B4,Q03164,P50750,P38398,P04150,P19338,P12956,Q9UBL3,Q9NYB0,Q96L73,P51858,Q13148,Q96EB6,Q00577,P22626,P20700,Q00403,Q99729,Q9UPR3,Q9Y619,P41440,Q96DT7,P09651,Q9NTG7,P38159,O00330,Q8ND82,Q00059,P67809,P23246,Q9H0D6,Q5T5X7,O95983,Q32MZ4,Q14103,Q9NXV6,Q86X55,O96028,Q9NPI1,O95785,Q8IZL8,Q15424,P05067 46 +Oxidative rna demethylase activity 0.5694964028776943 0.359497061783475 0.7192232754648502 1.0 0.9435358448874068 2 Q9C0B1 1 +Protein n terminus binding 0.2676917546682349 0.3561993766994694 0.7216912586944355 1.0 0.9442689366095418 51 P09874,P0DP25,Q969G3,O75381,O00165,Q15067,P40855 7 +Sodium channel inhibitor activity 0.5749877796948631 0.3538544307535782 0.7234479792439692 1.0 0.9456836329986524 3 P46934 1 +Anion channel activity 0.3297122425742395 0.343597289857974 0.7311491631394131 1.0 0.9478126347379648 12 P21796,Q9C0H2,P45880 3 +Lipase binding 0.5605755395683417 0.3337962018577479 0.7385333496902413 1.0 0.9511929066847634 2 Q96CS3 1 +Sphingosine n acyltransferase activity 0.5669206281028623 0.3314115684426455 0.7403336278255632 1.0 0.9524334000758348 3 Q96G23 1 +Single stranded dna helicase activity 0.3245518690503445 0.3267685134769224 0.7438429758290566 1.0 0.9524334000758348 14 Q14566 1 +Palmitoyl coa hydrolase activity 0.4049934848827549 0.3262955223246978 0.7442007756756521 1.0 0.9524334000758348 6 P50897 1 +Dynein complex binding 0.3660033973608133 0.3248663195796954 0.7452822485353552 1.0 0.9524334000758348 8 Q8TD16,Q06787,P25054,P49454 4 +Protein arginine n methyltransferase activity 0.428671920245777 0.3170438685461339 0.7512103156587031 1.0 0.9527150963874988 5 Q6P2P2 1 +Aspartic type peptidase activity 0.4016777734957558 0.3137989723428831 0.7536737249444854 1.0 0.9548807374862258 6 Q8TCT9 1 +N methyltransferase activity 0.2907019805169467 0.3106067571454801 0.7560995896606602 1.0 0.9550466078407088 27 O15047,Q14166,O96028,Q86X55,Q9H7B4,Q03164,Q6P2P2,Q96L73,Q8WTS6 9 +Sirna binding 0.4569536423841152 0.3047674623313215 0.7605432645901999 1.0 0.955799434853034 4 Q06787,P51608,Q08211 3 +Signaling receptor complex adaptor activity 0.3782504261727329 0.291479265703713 0.7706847993473593 1.0 0.9616387870644412 7 P37198 1 +Insulin receptor binding 0.3949094633057852 0.2887805250764653 0.7727493362089906 1.0 0.9624991732140452 6 P18031,Q13596,O60749 3 +Molecular function inhibitor activity 0.3174114258192264 0.2826103111337242 0.7774755752928983 1.0 0.965808168065712 12 Q9UII2,Q9UER7,P46934,Q96PU5 4 +Endopeptidase regulator activity 0.2875171079729329 0.2794768135236357 0.7798789295207724 1.0 0.9662216825921074 26 Q15418,P51812 2 +Channel regulator activity 0.2926721810055775 0.2694042273488359 0.7876186334300408 1.0 0.9719009061739876 22 P46934,P05771 2 +Acyl coa oxidase activity 0.542013100818079 0.2663290910344966 0.789985770501453 1.0 0.9735740129419316 3 Q15067 1 +Guanylate kinase activity 0.4414823146437537 0.2586567586213354 0.7959000859577532 1.0 0.9752404989073172 4 Q00013,O14936 2 +Peptide antigen binding 0.4109645560349052 0.2582496948675157 0.7962142073221883 1.0 0.9752404989073172 5 Q15392,P10321 2 +Volume sensitive anion channel activity 0.5357482725687859 0.251018017413118 0.8018001791913945 1.0 0.979511562712 3 Q9C0H2 1 +Importin alpha family protein binding 0.3650415111555653 0.2421208041274181 0.8086865583532439 1.0 0.9853448056523424 7 Q9ULW0,Q08379 2 +Glucocorticoid receptor binding 0.5243165467625858 0.2393925666840669 0.8108011933938104 1.0 0.9870623223924648 2 Q02790 1 +H4 histone acetyltransferase activity 0.4025722936116541 0.2319820446886359 0.8165519596899564 1.0 0.9892038614982112 5 Q92830 1 +Chemokine binding 0.5110791366906433 0.2092299789992525 0.834268710451813 1.0 0.9892038614982112 2 P09429 1 +Protein self association 0.2998774897947603 0.208723164505377 0.8346643557428699 1.0 0.9892038614982112 15 O43765,P46108,Q86U70,Q9Y282 4 +Glycosaminoglycan binding 0.2950765229901817 0.208681954378974 0.8346965283146268 1.0 0.9892038614982112 18 Q07021,P05067,P51858 3 +Peptidase activator activity 0.3133110133178475 0.207073141118282 0.8359527377584524 1.0 0.9892038614982112 11 Q9BXK5,P05067,Q9UL46 3 +Protein kinase a catalytic subunit binding 0.3699222126188368 0.2026480458350613 0.8394101338999107 1.0 0.9892038614982112 6 P13861,P49840,P41240,P15311,P10644 5 +Atpase coupled inorganic anion transmembrane transporter activity 0.4199743856335886 0.1999846177832899 0.8414926113472219 1.0 0.9907954245966538 4 P33527 1 +Nadp binding 0.2932256481246851 0.1991107517929491 0.8421761109071557 1.0 0.9907954245966538 18 P00374 1 +Rna polymerase i transcription regulatory region sequence specific dna binding 0.3902649769585286 0.195458903599408 0.8450337073175314 1.0 0.9916573262737166 5 Q9UIF9,Q12824,P51532,Q9NWS0 4 +Y form dna binding 0.5035020853815468 0.1794440542450388 0.8575890424378498 1.0 0.9988557898610564 3 Q9NS91 1 +Smad binding 0.2907435080352301 0.170857598952848 0.864335737464357 1.0 1.0 16 P09874,Q13573,Q9H6Z4,Q9Y4E8,Q9UPN9,Q9UNE7,P17844,P62942,Q00577 9 +Camp dependent protein kinase inhibitor activity 0.4920863309352475 0.1701901780644668 0.8648605758062811 1.0 1.0 2 P10644 1 +Antigen binding 0.3421318445747641 0.1640683639869089 0.869677326175027 1.0 1.0 7 Q15392,P10321 2 +Camp binding 0.4922279792745938 0.1573955662854015 0.8749331074985709 1.0 1.0 3 Q9Y4G8,P10644 2 +Peptide n acetyltransferase activity 0.2861808448244431 0.1556711301947215 0.8762922544685712 1.0 1.0 17 Q00403,Q92830,Q86UY6 3 +Cation chloride symporter activity 0.4811510791366863 0.1500127921677162 0.880754522777675 1.0 1.0 2 Q9BXP2 1 +Potassium chloride symporter activity 0.4811510791366863 0.1500127921677162 0.880754522777675 1.0 1.0 2 Q9BXP2 1 +Acetylcholine receptor binding 0.4799999999999956 0.1479869416116155 0.8823530738514291 1.0 1.0 2 O15258 1 +Anaphase promoting complex binding 0.397926864382374 0.1469511005844187 0.8831706172676776 1.0 1.0 4 Q16763,Q9HAW4,Q12834 3 +Modification dependent protein binding 0.2344040094350176 0.1465180538099284 0.8835124388350326 1.0 1.0 68 P46379,Q03164,Q13501,P07948,Q7Z4V5,Q9NS91,Q9NRR5,Q06787,Q12888,O43159,P54725,O95619,Q9Y4E8,Q9UER7,Q86X55,Q9ULU4,P45973,P29375,Q13185,Q9UPP1,Q14166,O60885,Q9NPI1,Q9H2V7,Q96EP0 25 +Histone methyltransferase binding 0.3357686468279339 0.1442451997191149 0.8853068499140639 1.0 1.0 7 Q96JN0 1 +Phosphatidylinositol kinase activity 0.3703167820573155 0.1416376640086606 0.8873662152509743 1.0 1.0 5 Q9BTU6 1 +Double stranded rna adenosine deaminase activity 0.4762589928057516 0.1415317389242318 0.8874498883582278 1.0 1.0 2 P55265 1 +Nadplus kinase activity 0.4748201438848876 0.1391013553660502 0.889370057212592 1.0 1.0 2 Q4G0N4 1 +Ww domain binding 0.3689516129032293 0.1382081020672382 0.8900759520266395 1.0 1.0 5 Q8N8S7,Q9Y2W2,Q9Y4G8,P50570 4 +Potassium ion transmembrane transporter activity 0.4812895797351582 0.137519134695831 0.890620469129864 1.0 1.0 3 P05023,Q9BXP2 2 +Camp dependent protein kinase regulator activity 0.4703511801957282 0.1191446103051185 0.9051607885174366 1.0 1.0 3 P13861,P10644 2 +Translation initiation factor binding 0.2759734788061772 0.1156939919982115 0.9078950679684324 1.0 1.0 18 P55010 1 +Jun kinase binding 0.4592805755395642 0.1146942871421092 0.9086874422460138 1.0 1.0 2 O60271 1 +K48 linked polyubiquitin modification dependent protein binding 0.3390272982248784 0.1115878366343064 0.9111502167438404 1.0 1.0 6 Q9NRR5 1 +Pyrophosphate hydrolysis driven proton transmembrane transporter activity 0.3023017059379816 0.1075752654121542 0.9143326184484468 1.0 1.0 9 P36543,Q9Y5K8,P06576 3 +Atpase coupled ion transmembrane transporter activity 0.3023017059379816 0.1075752654121542 0.9143326184484468 1.0 1.0 9 P36543,Q9Y5K8,P06576 3 +Mannose binding 0.3193122779919281 0.0970041868367356 0.9227230695177396 1.0 1.0 7 O75503 1 +Tat protein binding 0.3708609271523174 0.0923089234576451 0.9264525987487942 1.0 1.0 4 Q12824,P51532,P06748 3 +General transcription initiation factor binding 0.258206507191811 0.0907678243518652 0.9276770769305772 1.0 1.0 23 Q00403,O60869 2 +Nedd8 specific protease activity 0.4509870790001374 0.0902841845941808 0.9280613876867684 1.0 1.0 3 Q92905 1 +Mitogen activated protein kinase binding 0.2996147363723603 0.0872148680800017 0.930500721370807 1.0 1.0 8 Q96JB5,Q96EB6,P12270 3 +Vitamin d binding 0.4376978417266141 0.0862532393308923 0.931265109491517 1.0 1.0 2 P38435 1 +P53 binding 0.2563397752676035 0.0843022180586796 0.932816148926228 1.0 1.0 27 Q5VTR2,Q9NPI1,P61289,Q96EB6,Q9UER7,Q8WTS6 6 +Ubiquitination like modification dependent protein binding 0.3282527036255286 0.084271057924034 0.9328409229597868 1.0 1.0 6 Q9UER7,Q9Y4E8 2 +Notch binding 0.4458310471724231 0.0833796521342104 0.9335496674103376 1.0 1.0 3 Q2M2I8 1 +N acetyltransferase activity 0.2620497292917575 0.0797489378147501 0.9364369366215092 1.0 1.0 21 Q00403,Q969G3,O60318,Q86UY6,Q92830 5 +Neurexin family protein binding 0.4293525179856068 0.0768855391506228 0.9387146015780624 1.0 1.0 2 O14936 1 +Protein tyrosine kinase activator activity 0.4273381294963987 0.074755007668812 0.9404096402789496 1.0 1.0 2 Q8IZP0 1 +Chromo shadow domain binding 0.3599193780593045 0.0735586169913375 0.9413616007445648 1.0 1.0 4 Q6KC79,Q14739,Q13111 3 +G quadruplex rna binding 0.4352331606217414 0.0701949636330676 0.944038482877854 1.0 1.0 3 Q9H2U1,Q06787 2 +Transferase activity transferring one carbon groups 0.2269605894095205 0.0633839430068168 0.9494607731636532 1.0 1.0 68 O15047,Q14166,O96028,Q08J23,Q9H7B4,Q03164,P31939,O60725,P21964,Q52LJ0,Q6P2P2,Q05682,Q8WTS6 13 +Sumo binding 0.3475257278117518 0.0546199736278184 0.9564412258568756 1.0 1.0 4 Q8IZL8 1 +G protein coupled receptor binding 0.2482551550688733 0.0508623886038179 0.9594351762430888 1.0 1.0 30 Q07021,P46934,P0DP25 3 +Protein arginine omega n asymmetric methyltransferase activity 0.3952216465169671 0.0318981551730472 0.974553269851171 1.0 1.0 3 O60678,Q86X55 2 +Kinase activator activity 0.2529296608635401 0.0306562668341239 0.9755436687651632 1.0 1.0 20 Q9ULW0,Q9UER7,Q7KZI7,P0DP25 4 +Polyubiquitin modification dependent protein binding 0.253740851248414 0.0285252702804662 0.9772432134579 1.0 1.0 19 Q9NRR5,Q9NS91,Q13501 3 +O methyltransferase activity 0.2729270131560162 0.0275312047705937 0.9780360514671798 1.0 1.0 9 O60725 1 +Oxidoreductase activity acting on diphenols and related substances as donors 0.3886010362694198 0.0271631276847939 0.978329624692004 1.0 1.0 3 Q9UDW1,P08574 2 +Ubiquinol cytochrome c reductase activity 0.3886010362694198 0.0271631276847939 0.978329624692004 1.0 1.0 3 Q9UDW1,P08574 2 +Dna binding transcription repressor activity 0.2504085034161367 0.0253468949860343 0.979778269142207 1.0 1.0 12 Q96DT7,P04150,P51858 3 +Transmembrane receptor protein kinase activity 0.3854346574553732 0.0250439129024857 0.9800199371493334 1.0 1.0 3 P11717,Q15375 2 +Transmembrane receptor protein tyrosine kinase activity 0.3854346574553732 0.0250439129024857 0.9800199371493334 1.0 1.0 3 P11717,Q15375 2 +Insulin like growth factor binding 0.3389928057553907 0.0219555887133485 0.9824833820616644 1.0 1.0 2 P11717 1 +Dna directed dna polymerase activity 0.286948070970253 0.0219094476626359 0.9825201884399948 1.0 1.0 7 Q9NRG0 1 +Supercoiled dna binding 0.3087557603686649 0.0208663190956355 0.983352294239167 1.0 1.0 5 O75475,P26583,P09429,P23396 4 +Gtpase activating protein binding 0.305370034225309 0.0162195644129315 0.9870592273718468 1.0 1.0 5 P07437 1 +2 acylglycerol 3 phosphate o acyltransferase activity 0.3678756476683846 0.0148862932924491 0.9881228950804872 1.0 1.0 3 Q8NF37,Q96N66 2 +Peroxisome proliferator activated receptor binding 0.2693525179856058 0.0132782216652658 0.9894058232512316 1.0 1.0 2 P17096 1 +Centromeric dna binding 0.3101065361359031 0.0114857099788144 0.9908359308281642 1.0 1.0 4 P43246,P07199,Q99661 3 +Sumo transferase activity 0.3598157743235349 0.0110585473580645 0.991176735633454 1.0 1.0 3 P49792,O96006 2 +Chloride channel regulator activity 0.3083789231212152 0.0099672026414833 0.992047454572626 1.0 1.0 4 Q9H4A3,O15400,Q9UNK0 3 +Phosphatase binding 0.2309800525079044 0.0082140329484477 0.993446223626174 1.0 1.0 53 Q9NX63,Q15257,Q86XL3,Q9UJX3,Q92830 5 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d3d2d8a5169a9f6917282eb97013d0fcd4ee2685 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Bile acid transmembrane transporter activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H3 histone acetyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein lipase activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Microtubule severing atpase activity", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Mutsalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on metal ions", "Oxidoreductase activity acting on metal ions oxygen as acceptor", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein glutamic acid ligase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Store operated calcium channel activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type 5 metabotropic glutamate receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AACS", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP4M1", "APC", "APEH", "APEX1", "APEX2", "API5", "APMAP", "APOL2", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL8A", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD5", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD7", "BRIX1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CENPE", "CENPF", "CENPV", "CEP131", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COASY", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "CPD", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC8", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAM118B", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLVCR1", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FSCN1", "FSD1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GIGYF2", "GIT1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLPH3", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS4", "HAUS6", "HAUS7", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGN5", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "JUP", "KARS", "KAT2A", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT1", "LCOR", "LDAH", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRFIP1", "LRSAM1", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED17", "MED23", "MED24", "MED4", "MEN1", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORC3", "MORF4L1", "MOV10", "MPC2", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA20", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND4", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFS1", "NGDN", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OFD1", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBK", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTAR1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABAC1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP4", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RFX1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RTCB", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD7", "STARD9", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAOK2", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TLN1", "TM7SF2", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM201", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC1", "TTC26", "TTC4", "TTK", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TUT1", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBL5", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS11", "VPS16", "VPS18", "VPS25", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS52", "VRK1", "VRK3", "VTA1", "WARS", "WARS2", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR54", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WRN", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBED1", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF106", "ZNF148", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAK1", "ABCB1", "ABCB7", "ABCC1", "ABCC10", "ABHD10", "ABI1", "ACBD5", "ACOT8", "ACOX1", "ACP6", "ACTN1", "ADA", "ADAR", "ADD1", "ADI1", "AGPS", "AIFM1", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALDH1A2", "ALDH1B1", "ALDH6A1", "ALYREF", "AMOT", "ANAPC7", "ANGEL1", "ANKLE2", "ANP32A", "ANP32E", "APC", "APMAP", "APOL2", "APP", "APPL1", "ARFIP1", "ARHGAP1", "ASCC2", "ASH2L", "ASNA1", "ATAD2", "ATG4B", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5B", "ATP5H", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPIF1", "AUP1", "BAG6", "BAIAP2", "BAZ1B", "BAZ2A", "BCL2L13", "BCLAF1", "BEND3", "BICD2", "BRCA1", "BRD4", "BRD7", "BTAF1", "BUB1B", "C1QBP", "CALD1", "CALM3", "CALU", "CANT1", "CARM1", "CASK", "CASP2", "CBL", "CBX2", "CBX3", "CBX5", "CCAR2", "CCDC6", "CDC20", "CDC40", "CDK12", "CDK5", "CDK5RAP3", "CDK9", "CDKN2AIP", "CENPB", "CENPF", "CERS1", "CERS2", "CETN2", "CHAF1A", "CHAMP1", "CHCHD3", "CHKA", "CHMP1A", "CHRAC1", "CHST14", "CIRBP", "CLCN3", "CLINT1", "CLK3", "CLN5", "CLPP", "CLSPN", "COMT", "COPS5", "COQ6", "COX4I1", "COX7A2", "COX7A2L", "CPD", "CPOX", "CPSF7", "CPT2", "CPVL", "CRK", "CRTAP", "CSGALNACT2", "CSK", "CSTF2", "CTBP2", "CUTA", "CYB5B", "CYB5D2", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAXX", "DAZAP1", "DCUN1D4", "DCUN1D5", "DDX17", "DDX5", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHX36", "DHX9", "DNAJA3", "DNAJC10", "DNAJC8", "DNAJC9", "DNM2", "DOHH", "ECE1", "ECH1", "ECI2", "EDF1", "EIF4B", "EIF4H", "EIF5", "ELAVL1", "ENAH", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "ERAP1", "ERGIC3", "ERMP1", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC6", "EZR", "FAF2", "FAM208A", "FAM98B", "FDFT1", "FECH", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP9", "FLVCR1", "FMR1", "FNTA", "FNTB", "FTO", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "GAK", "GDE1", "GGCX", "GGPS1", "GHDC", "GLUD1", "GNAI3", "GNPAT", "GOLGA2", "GSK3A", "GSTK1", "GSTM3", "GTF2B", "H2AFX", "HAX1", "HCCS", "HDGF", "HDGFL2", "HDGFL3", "HEBP1", "HEXA", "HLA-A", "HLA-C", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGN5", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPK", "HNRNPM", "HNRNPR", "HTRA2", "ICMT", "IDH2", "IGBP1", "IGF2R", "INA", "ITM2C", "KAT2A", "KDELR1", "KDM1B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF18B", "KIF2C", "KIFAP3", "KIFBP", "KLC2", "KMT2A", "KPNA2", "KTN1", "L2HGDH", "LARP4", "LBR", "LCLAT1", "LCOR", "LDAH", "LDB1", "LEMD3", "LMNB1", "LNPEP", "LPCAT1", "LRRFIP1", "LTA4H", "LYN", "MARCKS", "MARK2", "MARK3", "MATR3", "MAVS", "MBD3", "MBOAT7", "MCM3AP", "MCM4", "MCM6", "MECP2", "MED17", "MED4", "MFSD10", "MFSD3", "MGEA5", "MICU2", "MIPEP", "MMGT1", "MORC3", "MPP1", "MSH2", "MSI2", "MTAP", "MTDH", "MYEF2", "NAA40", "NADK2", "NAP1L1", "NAP1L4", "NASP", "NCBP3", "NCL", "NCOA5", "NCOR1", "NDC1", "NDUFA13", "NDUFB10", "NDUFB3", "NDUFB8", "NDUFS3", "NEDD4", "NEDD4L", "NELFE", "NES", "NIPBL", "NLN", "NNT", "NOLC1", "NONO", "NOTCH2", "NPC1", "NPEPPS", "NPM1", "NR3C1", "NRDC", "NSD1", "NSD2", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC2", "NUCB1", "NUCB2", "NUCKS1", "NUDT12", "NUP107", "NUP153", "NUP214", "NUP58", "NUP62", "NUP88", "NUP93", "NUP98", "OPA1", "OSBPL3", "OSBPL6", "OTUD4", "P3H4", "P4HA1", "P4HA2", "PAF1", "PARN", "PARP1", "PARP2", "PAWR", "PBK", "PCBD1", "PCYOX1", "PDHX", "PDK1", "PDK3", "PDSS1", "PDSS2", "PECR", "PEF1", "PELP1", "PEX14", "PEX19", "PEX3", "PFDN6", "PGRMC1", "PGRMC2", "PHF8", "PI4K2A", "PIH1D1", "PIP4K2C", "PITRM1", "PLA2G15", "PLBD2", "PMPCA", "PNPLA6", "PON2", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PREPL", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRMT3", "PRMT9", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB6", "PSMD9", "PSME2", "PSME3", "PTAR1", "PTGES2", "PTK2", "PTPA", "PTPN1", "PURA", "QKI", "RABGGTA", "RAD18", "RAD23A", "RAD51AP1", "RANBP2", "RANBP3", "RAPGEF2", "RBM10", "RBM14", "RBM4", "RBM5", "RBMX", "RCN2", "RECQL4", "REPS1", "RER1", "RETSAT", "RHBDD2", "RIOK2", "RIPK1", "RNF20", "RNF219", "RNF31", "RNF40", "ROCK1", "ROCK2", "RPS3", "RPS6KA1", "RPS6KA3", "RRP8", "RSF1", 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17.57766990291262 0.8294573681393818 0.4043540785232756 2.1077508350863132 1.8331590876272783 0.898450188873912 0.3090371568059936 0.0250002930595481 0.0104419310742173 0.0398064357050217 0.0449350347407693 0.0206839034685982 +Abnormal circulating dicarboxylic acid concentration 11 39 2.322227864609272 0.0202206693534137 9.611650485436892 41.19660194174757 0.3636351001240374 0.5903090665886829 4.629439374954948 2.5633125009393525 0.8124485448597606 0.3243501761394795 0.1700518584481789 0.0473022522201117 0.034172513126223 0.1044322137967542 0.0002182411110436 +Abnormal lower motor neuron morphology 4 9 2.318405907561082 0.0204272712995183 2.1771844660194173 8.701456310679612 0.8468629004048428 0.2893246976958152 1.3759952567341256 1.207057649999096 1.1584035743641086 0.2695692447215745 0.0826539459562303 1.0 0.2147385524083838 0.1219531221716571 0.0063685282240186 +Knee flexion contracture 4 27 2.305551678518656 0.0211356959743871 6.37621359223301 26.20631067961165 0.4874196163722039 0.571576100604669 2.548884628142718 2.167424085317431 0.796597726565237 0.3234136220769761 0.0066515357374029 0.0030481683180534 0.0029226642017144 0.0168986737095617 0.0804683260329309 +Frontotemporal dementia 4 10 2.293133473537211 0.0218403217664699 3.4344660194174756 10.344660194174756 0.5931524822816645 0.4529040772840182 1.8896952177098856 1.3751065734754873 0.9402199282689112 0.308701646569884 0.0131362594618491 1.0 0.2223047329091382 0.0242110622206542 0.0075753503172145 +Amyotrophic lateral sclerosis 7 16 2.292724798670585 0.0218638538926292 4.453883495145631 16.203883495145632 1.0855969203541704 0.3037117925086244 2.3812188822255287 1.5445439412417563 1.0118111691913367 0.2917679915833991 0.0010653984680141 1.0 0.0588586045542952 0.002945649466309 0.0006928140913565 +Abnormal upper motor neuron morphology 5 11 2.265809324522005 0.0234630602294152 2.104368932038835 10.152912621359222 0.6668580581129538 0.4264480473015415 1.810508789672501 1.2708136152843803 0.93546763978058 0.305632736845798 0.004613560888322 1.0 0.1596960736798767 0.0087554356838108 0.0001461959825676 +Head titubation 2 7 2.254833690348172 0.0241437697271242 1.5388349514563109 6.640776699029126 0.7750159292999356 0.332564533403015 1.215173726819014 0.6010406659915046 1.0776448528926763 0.2851375019771297 0.001354096353283 1.0 0.1094892401774078 0.00262770885776 0.0182159139614431 +Motor neuron atrophy 8 22 2.2432269207020794 0.0248821851469565 5.410194174757281 22.424757281553397 0.8356342611289532 0.3959768073616548 2.754377444710008 1.6813276911909307 0.954775311801755 0.3176984078794489 0.000367382237415 1.0 0.0832345551471358 0.0012377122057681 0.0006053327615549 +Hyperconvex nail 3 8 2.2338574517418457 0.0254924539118412 2.405339805825242 7.939320388349515 0.7351828941114927 0.3065172604341125 1.3467943353086171 0.7527989998960608 1.0793151443208264 0.2411455315204656 0.001354096353283 0.0550816697898294 0.0056684159955205 0.000142755965642 0.0020183200628615 +Abnormal visual field test 2 6 2.231099979756336 0.0256745071011097 1.327669902912621 4.230582524271845 0.1762266305915039 0.415534143350189 1.137153407249188 1.1006338202583732 1.177482986201558 0.3081885114514395 0.0287436893658769 0.0639684350193291 0.1265462710440741 0.0439142352380576 0.0280386150660574 +Abnormal corpus striatum morphology 4 18 2.225429408719473 0.0260524251195715 3.783980582524272 16.274271844660195 0.5436026262586074 0.5269340846045785 2.1360147265981855 1.9458739529228473 0.8481478897769046 0.3232524565257521 0.0035028921767924 0.0104419310742173 0.0398064357050217 0.007920049564759 0.0206839034685982 +Abnormality of alkaline phosphatase level 6 24 2.220451640400023 0.0263881249402113 5.424757281553398 21.550970873786408 0.2837846270756372 0.4096308965627429 3.0903339262997473 2.8582743162812116 1.1598915940568888 0.2934678757183479 0.2569063230690206 0.2143583684675494 0.3896854720293997 0.1257511849434855 0.0112872973833843 +Hepatic failure 9 51 2.218077402482728 0.0265495553013446 12.25242718446602 48.050970873786405 0.7424989852941342 0.3814651163177168 5.527018274076851 5.448329576476532 1.3577793424610205 0.3539023729255708 0.0465910014742782 0.0831018560335817 0.0166529196858764 0.0008010177305408 0.0106866772399702 +Basal ganglia cysts 2 7 2.2079881907041963 0.0272450963915524 1.5436893203883495 6.509708737864078 0.6375864218957229 0.3423964855972016 1.553428397761971 0.5418441296142611 1.195152711044975 0.2990830010801169 0.0002313053102545 0.0325017468768143 0.0018609890552042 0.0004573905935078 0.0034775277607499 +Skin nodule 6 22 2.183818156031656 0.0289756129117129 6.070388349514563 21.26456310679612 0.7442674094202993 0.3924071478475022 2.7239314899251803 2.029014432281319 1.0984628042075235 0.3129154853478004 0.0327287831050519 0.2578448493622087 0.1226746045160812 0.0660458541210367 0.0328483629407697 +Abnormal caudate nucleus morphology 2 12 2.180794439914856 0.0291986240121038 2.8519417475728157 10.133495145631068 0.4630014218675518 0.4635627378613905 1.7037711217888412 1.7774598482419672 0.9891574305728495 0.3131768373752813 0.0072083457450835 0.0944323477659319 0.1837383274168749 0.0135296171343662 0.0798154053066686 +Abnormality of female external genitalia 11 38 2.155603116360099 0.0311146690132777 8.264563106796116 35.45873786407767 0.5074740553158107 0.5884020666172534 3.822570496076409 4.480350449974391 0.698609670750091 0.3175234627560208 0.4018193094394737 0.4315404604316775 0.317502679856318 0.0254693060714534 0.0648047463329864 +Oromandibular dystonia 2 6 2.137265011948413 0.0325764429112913 1.730582524271845 4.956310679611651 1.1882502597012077 0.2382412593757527 1.131086190944388 1.1979083634266432 0.9893427275402558 0.2482274576089271 0.0287436893658769 1.0 0.1265462710440741 0.0439142352380576 0.0280386150660574 +Posterior embryotoxon 9 19 2.1312008668723803 0.0330725976373313 5.400485436893204 18.211165048543688 0.5603270949007155 0.5260153972846668 2.4736082204804974 3.2255911781388433 0.9025074564453092 0.3301763927361542 0.6364717118113741 1.0 0.3955810682553247 0.0367529115341812 0.0397377338982377 +Decreased circulating gonadotropin concentration 2 5 2.113793126462568 0.0345329403005965 1.412621359223301 3.5558252427184467 -0.2404208370996299 0.4675591006565589 0.98268303333771 1.1613893790836225 1.1274816532439296 0.3066349573637341 0.0327528823448254 1.0 1.0 0.0498779046475234 0.0338099842169397 +Hemifacial spasm 2 5 2.070380204166874 0.0384167541408473 1.3519417475728157 3.699029126213592 0.225368556444307 0.5157856458788552 1.092747990784671 0.9959622507790676 1.007986177172795 0.3130395016973888 0.2231322746699767 1.0 1.0 0.2731207001200411 0.0228394808772788 +Pathologic fracture 11 20 2.042895647780128 0.0410627692592575 4.257281553398058 15.072815533980584 0.983166532607372 0.3143076297274698 2.133145812327421 2.2800397788540345 1.0713003315034937 0.2893419439464214 0.1721899185646328 1.0 1.0 0.0678108138951911 0.0024763006502838 +Prominent supraorbital ridges 2 12 2.039245265768813 0.0414255552858848 3.3932038834951457 11.063106796116504 -0.3609647115745727 0.5735120172179967 2.122636304401114 1.397257389279284 0.7192343647605209 0.2716644776562676 0.0211783554141664 1.0 0.0354914601129098 0.0383377547470353 0.1905468417868487 +Underdeveloped supraorbital ridges 4 12 2.0330144389662697 0.0420510642521392 4.665048543689321 12.08980582524272 0.8524762858030893 0.4193185978455835 2.3718498265247017 1.7978393075824093 0.8920190977636392 0.3291411492922084 1.0 1.0 1.0 0.0998367022916053 0.0717558982580182 +Cutaneous photosensitivity 6 26 2.030658488016414 0.0422896501463601 4.45873786407767 23.25728155339806 0.4951941865269984 0.5365203315345327 2.635778170171519 2.496953559053009 0.8423686703892482 0.3178790898940878 0.1042745607274985 0.0313211948286675 0.1100932826860655 0.1714591409165242 0.0238799220201886 +Tongue fasciculations 3 13 2.02420111949282 0.0429494624534594 2.5145631067961167 11.366504854368932 0.4464487176204783 0.5205477879363428 1.4421806417016856 1.148720021097238 0.7641925566649829 0.2764297929505911 0.0062661916687399 0.0039064712270754 0.0155240337321844 0.0011993766429203 0.0144964406909979 +Degeneration of the lateral corticospinal tracts 4 8 2.023026212644228 0.0430704450658794 1.91747572815534 6.543689320388349 0.7561294413609913 0.4260862878985212 1.2219614333343374 1.301803819717693 0.8237278722604997 0.3013218286302411 0.30866211576403 1.0 0.1677870330809631 0.3727200206787977 0.0120515986398723 +Aplasia hypoplasia of the patella 1 6 2.015834732239318 0.0438172603600508 1.5218446601941749 5.584951456310679 0.5626147938318666 0.4502183820300943 1.1913965433231544 1.2828467840821514 0.9140365060117206 0.2971205043347708 0.0714454283497719 0.1029565435856987 0.1993869387044997 0.1060727287920157 0.3097803043008575 +Thoracic scoliosis 3 11 2.0134823214676096 0.0440639129441342 2.895631067961165 11.815533980582524 0.7054864621280054 0.4260251550564725 1.907135385454388 1.092761468704903 0.8938736368000172 0.2999782404089314 0.4083005998785439 1.0 1.0 0.4846912912858679 0.1423023069394473 +Abnormal size of the clitoris 5 17 2.01045534603331 0.0443830177872139 5.004854368932039 16.946601941747574 0.4852727204627456 0.543895314626013 2.395378991469236 2.9431610881948327 0.7632431622419519 0.3038297834937744 0.1123632240039368 0.2507644527164699 0.1163398228410075 0.0034676048515423 0.0756252939231378 +Coxa vara 3 15 2.0051229711944707 0.044949902278879 4.310679611650485 13.54126213592233 0.853738655548226 0.4218003203060939 1.9720332330132235 1.9928869528934432 0.8140335419312188 0.3116542205645756 0.1860320011381842 0.0158345246348345 0.0588586045542952 0.2616785322574622 0.1376237189726102 +Abnormality of the distal phalanges of the toes 4 7 1.9979242737174168 0.0457248705710562 2.094660194174758 5.058252427184466 1.0467054837889296 0.2409661092181722 1.19191069217632 0.9786581135773657 1.170071232541671 0.254087308422285 0.2527518399380014 1.0 1.0 0.307957256786686 0.1641299211995837 +Bulbar signs 6 15 1.997781131708407 0.0457403938093592 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 0.0031246134985399 0.1403531442218371 0.0376249374527164 0.0070923684446229 0.0007278251765531 +Tinnitus 5 16 1.9877483142657717 0.0468395325958226 3.8932038834951457 13.99514563106796 0.4805222542355059 0.4721664152250915 2.15835527708504 1.954575346364738 0.945493760855854 0.2980035751111249 0.0410866703643027 0.1723099894081314 0.0563311776114605 0.0720513532108381 0.0121842961258669 +Elbow flexion contracture 2 26 1.984966975080404 0.0471481459037597 6.728155339805825 25.49757281553398 0.4005296068252059 0.5766090162654979 3.258876376606738 2.9283505301145505 0.8105730741101873 0.3220832838154132 0.1379711291481713 0.0395283360833688 0.0264876267470493 0.2210522410556178 0.4137246468241853 +Basal ganglia gliosis 2 10 1.9839615222010163 0.0472601295605683 2.4902912621359223 8.478155339805825 0.2204804574430971 0.4876803762866264 2.0090578656174585 1.0483498337519768 1.0103998561078729 0.3128515878399759 0.001354096353283 0.0550816697898294 0.1094892401774078 0.00262770885776 0.0182159139614431 +Visual acuity test abnormality 2 5 1.9786911053335825 0.0478507950166877 1.4296116504854368 3.3349514563106797 -0.1346623814506991 0.4819433300077458 1.0462122362883222 1.2025223279007424 1.11853114112665 0.3079257538350568 0.2527518399380014 1.0 1.0 0.307957256786686 0.0338099842169397 +Abnormal circulating long chain fatty acid concentration 3 5 1.9743864124162611 0.0483378218601622 2.0728155339805827 4.861650485436893 1.0288291622755297 0.284696092465088 1.384567800831184 1.563474222630441 1.0358408470651057 0.2764983518284591 0.2812476453561096 1.0 0.1515272625734178 0.00062382482254 0.0079931710216612 +Abnormality of hepatobiliary system physiology 25 85 1.9653796571203503 0.049370312192295 18.737864077669904 78.23543689320388 0.6753867917166245 0.4584905924436965 8.191827759406172 8.347745847320367 1.279744288983872 0.374212423907768 0.0281655497028842 0.0350541036074757 0.0158491381338637 8.517236849246114e-05 0.0012423815885947 +Limb joint contracture 18 105 1.9646340371877755 0.0494566095306268 21.16747572815534 100.42233009708738 0.6687590042181877 0.5853612155895958 7.458858708924721 11.434332835202127 0.8235264349573469 0.3682957054317731 0.0237735037597325 0.0464216349345917 0.059540268273496 0.0486575147202899 0.1134765871835954 +Hypocholesterolemia 0 8 1.9636202866911845 0.0495741429967238 3.2645631067961167 8.048543689320388 1.205673434171466 0.2055905154190861 1.747510449264718 1.0646904903887575 1.232151298114248 0.2464368010987078 0.2231322746699767 0.0595353304203936 0.1180585699575878 0.2731207001200411 0.4779737602264646 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2c313076ded401ee07daee02f1771ce9d455f749 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 4664, + "title": "Average number of proteins per term", + "value": 25.198542024013722 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d39df71f6af9f9498bf33031cabcaaf24f565712 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a6203e0311130de74c42b2ce30f6a869048f2fe0 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1464 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Titubation 0.7472256976488252 2.805049139420895 0.0050308909323706 0.999999999939192 0.2125045604521105 12 Q99720,P35637,Q5T8D3,Q9Y5Y0,P20700 5 +Primary adrenal insufficiency 0.7040214536274538 2.7674180242198516 0.0056502253424248 0.9999999999966678 0.2125045604521105 16 Q13423,Q969G3,O75381,P56589,P40855,P31749 6 +Abnormal full field electroretinogram 0.8979951730552589 2.7507794641749377 0.0059453654418504 0.9999999999991654 0.2125045604521105 7 P00846,Q15067,P37198 3 +Abnormal light and dark adapted electroretinogram 0.8979951730552589 2.7507794641749377 0.0059453654418504 0.9999999999991654 0.2125045604521105 7 P00846,Q15067,P37198 3 +Morphological abnormality of the pyramidal tract 0.5994536688597165 2.7495193346837508 0.0059682741701745 0.9999999999992506 0.2125045604521105 25 O00400,Q9Y619,P00846,P35637,Q13501,Q13148,O95831,Q9H9P8,Q12768 9 +Abnormality of the supraorbital ridges 0.5827403465518427 2.586272417699208 0.0097020216867078 1.0 0.2459251584065515 24 Q9UPP1,P51812,O75381,P56589,P38159,P40855,P98175 7 +Myoclonic spasms 0.8545480967660575 2.5583298104619137 0.0105176288281654 1.0 0.2480076730865592 7 P00846,P31749,Q10713 3 +Pendular nystagmus 0.8909359000627008 2.546914417440966 0.0108680082944081 1.0 0.2513770695892462 6 P00846,P49902 2 +Atrophy degeneration involving the corticospinal tracts 0.674934727947576 2.540577231818431 0.0110669648390224 1.0 0.2513770695892462 15 O00400,P00846,P35637,Q13501,Q13148,Q12768 6 +Abnormal astrocyte morphology 0.6402131577419004 2.512838368808361 0.0119764191904445 1.0 0.2598047400196905 18 P00846,P48735,Q13501,O95831,P37198 5 +Contractures of the joints of the upper limbs 0.408766115291494 2.5082870427501236 0.0121318070926268 1.0 0.261085791603492 73 P37268,Q96AY3,P42892,Q9NR77,Q96L73,P06753,P02545,Q9Y619,O95155,Q9Y5Y0,Q8WVQ1,Q99567,Q15392,P35637,P23786,Q99720,P57740,O75844,Q96L58 19 +Generalized amyotrophy 0.5599099706742978 2.4940492760051853 0.0126295010286134 1.0 0.2641434654594319 26 Q8IY17,Q99567,P35637,Q9Y2U8,Q03252,Q13501,Q13148,P06753,P22626 9 +Biliary cirrhosis 0.8314023091460944 2.453975604755741 0.0141286566021621 1.0 0.2828156840879146 7 P09601,P21266 2 +Symptomatic seizures 0.7803701145146344 2.438087585305091 0.0147651960460184 1.0 0.2905690901208019 8 P31751,Q13423,P53985 3 +Decreased circulating cortisol level 0.7608554524100822 2.430739832646331 0.0150680299431722 1.0 0.2940472454182233 9 Q13423,P31749 2 +Horizontal nystagmus 0.563752550438947 2.4102095333534717 0.0159433610443411 1.0 0.3022757557349879 23 O95831,P00846,P37198,P20700 4 +Abnormal neuron morphology 0.5375047097305244 2.4063413848217907 0.0161131994707601 1.0 0.3042589568082002 28 Q16637,Q8IY17,Q99720,P35637,Q13501,Q13148,Q15165,Q92804,P22626 9 +Morphological abnormality of the corticospinal tract 0.6211330889979675 2.3906344646541826 0.0168192889768279 1.0 0.3076280932859824 18 O00400,P00846,P35637,Q13501,Q13148,Q12768 6 +Hypoglycemic seizures 0.8132221723801448 2.371106606099661 0.0177349149354439 1.0 0.3195413561106264 7 P31751,Q13423,P53985 3 +Wormian bones 0.6021088704854745 2.336878934433485 0.019445479976855 1.0 0.3334327890148975 19 Q96AY3,Q04721,O75718,Q32P28,O95831,O75844 6 +Abnormal circulating dicarboxylic acid concentration 0.4749323951261471 2.322227864609272 0.0202206693534137 1.0 0.3416085774444353 39 P37268,Q9UJS0,P36551,P41440,Q16134,P48735,P23786,P22695,P40855,P55263,Q9H9P8 11 +Abnormal lower motor neuron morphology 0.7384274324022622 2.318405907561082 0.0204272712995183 1.0 0.3427078897156608 9 Q99720,P35637,Q13501,Q13148 4 +Knee flexion contracture 0.5304529336814237 2.305551678518656 0.0211356959743871 1.0 0.3508074235748811 27 P37268,Q96AY3,P23786,P49902 4 +Frontotemporal dementia 0.7158715129622982 2.293133473537211 0.0218403217664699 1.0 0.3590711105798906 10 P05067,P22626,P35637,Q13501 4 +Amyotrophic lateral sclerosis 0.62549327502909 2.292724798670585 0.0218638538926292 1.0 0.3590711105798906 16 Q99720,P35637,Q13501,Q13148,Q15165,Q92804,P22626 7 +Abnormal upper motor neuron morphology 0.6809419921923097 2.2658093245220052 0.0234630602294152 1.0 0.3630031164821004 11 Q8IY17,Q99720,P35637,Q13501,Q13148 5 +Head titubation 0.7880035283778352 2.2548336903481716 0.0241437697271242 1.0 0.3667965537697318 7 Q99720,P35637 2 +Motor neuron atrophy 0.5538810812233482 2.2432269207020794 0.0248821851469565 1.0 0.3755679984640943 22 Q16637,Q99720,P35637,Q13501,Q13148,Q15165,Q92804,P22626 8 +Hyperconvex nail 0.7386315983367062 2.2338574517418457 0.0254924539118412 1.0 0.3786522453656936 8 P42892,P51812,Q9Y619 3 +Abnormal visual field test 0.8188110049202459 2.2310999797563356 0.0256745071011097 1.0 0.3789508986765763 6 P00846,P31749 2 +Abnormal corpus striatum morphology 0.5957391588797465 2.2254294087194735 0.0260524251195715 1.0 0.3833076049138218 18 O95169,O95831,P00846,P37198 4 +Abnormality of alkaline phosphatase level 0.5341295353495459 2.220451640400023 0.0263881249402113 1.0 0.3858125853327455 24 Q96AY3,Q9UJS0,P22681,Q13501,Q01130,P22626 6 +Hepatic failure 0.4291434581278291 2.218077402482728 0.0265495553013446 1.0 0.3869597685170978 51 O43772,Q9Y619,P22830,P00846,O75381,P56589,P23786,O15460,P40855 9 +Basal ganglia cysts 0.777936092073499 2.2079881907041963 0.0272450963915524 1.0 0.3946308371745365 7 P00846,P23786 2 +Undetectable light and dark adapted electroretinogram 0.9226666696690567 2.1887398340460567 0.0286157549685055 1.0 0.3995924586021254 4 P00846 1 +Skin nodule 0.5457818457742581 2.183818156031656 0.0289756129117129 1.0 0.4022091030363958 22 P25054,P35637,P48735,P31749,P34913,Q9NZ08 6 +Abnormal caudate nucleus morphology 0.6359179660996024 2.180794439914856 0.0291986240121038 1.0 0.4037961471020806 12 O95169,P00846 2 +Abnormality of female external genitalia 0.4605600047670506 2.155603116360099 0.0311146690132777 1.0 0.4218570240637426 38 P02545,Q9Y619,Q08J23,O75381,Q15392,P04150,P31939,P56589,O95155,P40855,P53701 11 +Oromandibular dystonia 0.797870374510876 2.137265011948413 0.0325764429112913 1.0 0.4291992365487652 6 Q99720,P35637 2 +Posterior embryotoxon 0.5715384748454496 2.1312008668723803 0.0330725976373313 1.0 0.429667396603102 19 Q15056,Q04721,O75381,P56589,Q96DF8,P21964,P40855,Q8WYQ5,P53701 9 +Decreased circulating gonadotropin concentration 0.8430031113883345 2.1137931264625673 0.0345329403005965 1.0 0.437492572988036 5 Q8IY17,P31749 2 +Hemifacial spasm 0.8329097379235428 2.070380204166874 0.0384167541408473 1.0 0.4672279682908088 5 P31749,Q10713 2 +Pathologic fracture 0.5485121734981464 2.042895647780128 0.0410627692592575 1.0 0.4879524723875301 20 O15269,O75845,Q13126,Q04721,Q14108,P09651,P22681,O94761,Q01130,Q96L58,P22626 11 +Prominent supraorbital ridges 0.6117417285706679 2.039245265768813 0.0414255552858848 1.0 0.4879524723875301 12 P51812,P38159 2 +Underdeveloped supraorbital ridges 0.6106856871410046 2.0330144389662697 0.0420510642521392 1.0 0.4940205634054845 12 O75381,P98175,P56589,P40855 4 +Cutaneous photosensitivity 0.5010796253478126 2.030658488016414 0.0422896501463601 1.0 0.4955751966900088 26 P37268,Q08J23,Q14108,P22830,Q9Y3Z3,Q06136 6 +Tongue fasciculations 0.603251371490855 2.0242011194928193 0.0429494624534594 1.0 0.4982992360272009 13 O95831,Q16637,Q9BQT8 3 +Degeneration of the lateral corticospinal tracts 0.6965244404928204 2.0230262126442273 0.0430704450658794 1.0 0.4984629175862572 8 P35637,O00400,Q13501,Q13148 4 +Aplasia hypoplasia of the patella 0.7710810536414106 2.015834732239318 0.0438172603600508 1.0 0.5021221187205828 6 Q96AY3 1 +Thoracic scoliosis 0.635466557488599 2.0134823214676096 0.0440639129441342 1.0 0.5037110048319661 11 O75844,Q9UHX1,P06753 3 +Abnormal size of the clitoris 0.5722788694602662 2.01045534603331 0.0443830177872139 1.0 0.504883890145283 17 Q9Y619,O75381,P56589,P31939,P53701 5 +Coxa vara 0.5870288564360597 2.0051229711944707 0.044949902278879 1.0 0.5052530633114167 15 O95831,Q96AY3,O75718 3 +Abnormality of the distal phalanges of the toes 0.7334158445547015 1.9979242737174172 0.0457248705710562 1.0 0.5091484408755406 7 O75844,O75431,Q8WVQ1,P02545 4 +Bulbar signs 0.5858575995663069 1.997781131708407 0.0457403938093592 1.0 0.5091484408755406 15 Q15043,Q99720,P00846,P35637,O43681,P06753 6 +Tinnitus 0.5771453329450865 1.9877483142657713 0.0468395325958226 1.0 0.5162090029753883 16 Q9NR28,Q15043,Q9NR77,O95831,P31749 5 +Elbow flexion contracture 0.4954226866595415 1.984966975080404 0.0471481459037597 1.0 0.5162090029753883 26 P37268,Q96AY3 2 +Basal ganglia gliosis 0.6574341941042217 1.9839615222010163 0.0472601295605683 1.0 0.5162090029753883 10 O95169,P00846 2 +Visual acuity test abnormality 0.8117346735602897 1.9786911053335825 0.0478507950166877 1.0 0.5214395045743732 5 Q969G3,P31749 2 +Abnormal circulating long chain fatty acid concentration 0.8107451457725737 1.9743864124162611 0.0483378218601622 1.0 0.5245889325340924 5 O75381,P56589,P23786 3 +Abnormality of hepatobiliary system physiology 0.3665843694576467 1.9653796571203503 0.049370312192295 1.0 0.5276436408306293 85 P22830,P00846,P55263,Q10713,Q9Y619,Q8N511,O15118,P22695,P22681,Q00059,O75845,Q6NUQ1,O75381,Q16625,P23786,O15460,Q01130,Q9UER7,O43772,Q9NWS8,O95169,P56589,O95453,O75787,P40855 25 +Limb joint contracture 0.3554198352424601 1.9646340371877753 0.0494566095306268 1.0 0.5276436408306293 105 P37268,Q96AY3,Q8WVQ1,Q9Y619,Q08J23,Q99720,P42892,P35637,Q15392,P23786,P49902,P06753,Q9NR77,O95155,Q86XL3,Q9Y5Y0,O75844,Q9H9S5 18 +Astrocytosis 0.7238635015867684 1.9522459312468137 0.0509090133734526 1.0 0.5276436408306293 7 P00846,P37198 2 +Melanocytic nevus 0.5846672398020105 1.9490406203826556 0.0512905739455125 1.0 0.5304195939731049 14 Q96AY3,P31749 2 +Insulin resistance 0.5440901454438645 1.942808254116408 0.0520393302408908 1.0 0.5369722040785724 19 P31751,P18031,P02545,Q9UKG1,O75431,Q03252,O00330,O75844,Q14191 9 +Arthralgia 0.4385103799091692 1.941483916640224 0.0521996083898397 1.0 0.537367120142181 38 Q04721,P25054,P02545,P28070,Q9Y2U8,P22681,O15460,Q03252,P14174,Q01130,Q96HY6,Q9NZ08 12 +Metaphyseal striations 0.7212353633572572 1.9396416916169883 0.0524232503569237 1.0 0.537367120142181 7 P00813 1 +Head tremor 0.5890627506174858 1.9384697119188523 0.0525659425687305 1.0 0.5376481494310515 13 Q99720,P35637 2 +Abnormality of the clitoris 0.533331256658681 1.9353773901486864 0.0529440017668429 1.0 0.5387846375816994 20 Q9Y619,O75381,P56589,P31939,P53701 5 +Agitation 0.4447702111646312 1.9337885054046744 0.0531391366397044 1.0 0.5387846375816994 35 Q13148,P48449,P42892,P35637,P43243,Q6Y7W6,Q13501,Q15165,Q92804,P05067 10 +Abnormal electroretinogram 0.4445666201033364 1.9318562154604064 0.0533772552739419 1.0 0.5400249861120725 35 Q8IY17,P00846,Q15067,Q9Y5Y0,Q15051,P37198 6 +Abnormality of circulating adrenocorticotropin level 0.6194133007709174 1.922804844625045 0.0545045634521283 1.0 0.5443453617574451 11 Q969G3,Q13423,P31749,P04150 4 +Dermal atrophy 0.4726431860613372 1.9131138041613889 0.0557334849320063 1.0 0.5518916639551543 29 P02545,O75844,Q15392,O95453,Q9Y2U8,Q9NWM8,Q8NCH0,P53701,Q96L58 9 +Mandibular aplasia 0.796133355224993 1.91061800521356 0.0560536888044262 1.0 0.5531044046107683 5 P53701 1 +Atrophy degeneration involving the caudate nucleus 0.7951365586453547 1.9062540761538016 0.0566172493505323 1.0 0.5570946223014408 5 P00846 1 +Delayed cranial suture closure 0.465903662077399 1.899015093245353 0.0575624915400132 1.0 0.5599072238556835 30 P51812,O75718,Q08J23,Q32P28,O75381,O95155,P40855,Q8NCH0,O75844 9 +Abnormal arterial physiology 0.4803087037851719 1.8976886516164584 0.057737108380613 1.0 0.5599072238556835 27 P02545,O15460,Q9NWM8,Q9Y3Z3,O75844,P05067,Q9NZ08 7 +Fatigable weakness of bulbar muscles 0.5620674580772664 1.8907037742015715 0.0586638983629175 1.0 0.5644908464634402 16 P35637,Q13501,Q13148,Q15165,Q92804,P06753 6 +Young adult onset 0.6395145778890843 1.8871304467478849 0.0591427824549219 1.0 0.566410549013873 10 Q14566,P36551,P02545 3 +Anterior rib cupping 0.7891514902433786 1.8800154159570908 0.0601059769562628 1.0 0.5721107684163468 5 O95831 1 +Abnormal muscle fiber morphology 0.3616387209687362 1.874399102992204 0.0608754370473507 1.0 0.5759087999773712 70 P51114,Q9H9S5,O43676,Q70HW3,Q99720,P00846,P35637,P23786,P05067,Q13501,P61978,O95831,P06753,O14979,P22626 15 +Abnormal circulating lipid concentration 0.3606054039951067 1.8688954429977416 0.0616373624488804 1.0 0.5761055279791146 82 P37268,O43772,P31751,P28070,P22830,O75381,Q15392,P56589,P23786,P40855,O75844,P34913 12 +Raynaud phenomenon 0.7374125679476826 1.861074381097119 0.0627336734853116 1.0 0.5816895688578402 6 O75844,Q9Y3Z3 2 +Abnormality of metacarpal epiphyses 0.7358461117250376 1.8538176356023957 0.0637652545460136 1.0 0.589276818760713 6 P51812 1 +Abnormality of lipoprotein cholesterol concentration 0.5684854517874918 1.8486010877323609 0.0645154355254489 1.0 0.589276818760713 14 P37268 1 +Respiratory failure 0.359576271080939 1.847689557333729 0.0646472655115137 1.0 0.589276818760713 69 P33991,Q16637,Q9Y619,P53701,Q70HW3,O95169,Q8N183,P35637,P43243,P23786,Q13501,Q13148,Q15165,Q92804,P06753,Q9H9S5 16 +Centrally nucleated skeletal muscle fibers 0.662142248422652 1.8474002809475063 0.0646891485161118 1.0 0.589276818760713 8 P51114,P22626 2 +Hypolipoproteinemia 0.6621261343651648 1.847317265526752 0.0647011720731538 1.0 0.589276818760713 8 P37268,Q9UJS0 2 +Abnormal labia minora morphology 0.6995722619958789 1.835156195667664 0.0664825494657219 1.0 0.5957667319577665 7 P31939 1 +Central heterochromia 0.9464748201438846 1.8334572684956147 0.0667345977298852 1.0 0.5957667319577665 2 Q8IY17 1 +Arm dystonia 0.8348175611039762 1.8293818247866291 0.0673424284388479 1.0 0.5980821060044867 4 P35637 1 +Hemihypertrophy 0.9450359712230216 1.8275145046965624 0.0676224473714373 1.0 0.5980821060044867 2 P31749 1 +Reduced forced vital capacity 0.7770381740889734 1.826722934075069 0.0677414381978607 1.0 0.5980821060044867 5 Q9BQT8,Q9H9S5,P06753 3 +Abnormal ldl cholesterol concentration 0.570073332674204 1.822615961009537 0.0683615765140732 1.0 0.5980821060044867 13 P37268 1 +Axonal degeneration 0.6955824377176505 1.8157997116108744 0.0694011015592299 1.0 0.5980821060044867 7 Q9BQT8,Q6DKK2 2 +Abnormal iliac wing morphology 0.5686206031970575 1.8137019379854469 0.0697236265657297 1.0 0.5980821060044867 13 O95831 1 +Cardiorespiratory arrest 0.8309335679363726 1.813228890988026 0.0697965255720194 1.0 0.5980821060044867 4 O43772 1 +Cardiovascular calcification 0.6554889078086262 1.8130696976085956 0.0698210721671674 1.0 0.5980821060044867 8 O75844,Q9Y3Z3,P02545 3 +Pseudoepiphyses 0.725830925303119 1.807306790026454 0.0707144579308587 1.0 0.5980821060044867 6 P51812 1 +Pseudoepiphyses of hand bones 0.725830925303119 1.807306790026454 0.0707144579308587 1.0 0.5980821060044867 6 P51812 1 +Slender long bone 0.5489842463828939 1.8057883709902545 0.0709514026234439 1.0 0.5980821060044867 16 P37268,Q96L58,Q9Y619 3 +Biliary tract abnormality 0.4691644686795668 1.8049346826141293 0.0710849037374978 1.0 0.5980821060044867 27 O96028,Q14108,O43681,P09601,P21266,Q10713 6 +Abnormality of the posterior pituitary 0.6238788804581886 1.8019011454627352 0.0715609599872377 1.0 0.5980821060044867 10 Q969G3,P31749,Q9UHX1 3 +Insulin resistant diabetes mellitus 0.6376706372146418 1.7961187256910642 0.0724756369059649 1.0 0.5993375363996816 9 P31751,P02545,Q9UKG1,O75431,O75844 5 +Fatigable weakness of swallowing muscles 0.5579287764700782 1.7825763869420128 0.0746552864725318 1.0 0.6066067179579939 14 P35637,Q13501,Q13148,Q15165,Q92804 5 +Abnormal head movements 0.5618388883473027 1.7719959992903356 0.0763952213331773 1.0 0.6112176255198434 13 Q99720,P35637 2 +Chromosome breakage 0.5667964401666185 1.7706517241607145 0.0766186349654127 1.0 0.6112176255198434 12 P33991,Q969G3,P38398,Q9BXW9,P13073,P31749 6 +Abnormal larynx physiology 0.5435774040246496 1.7705101911380776 0.0766421882021177 1.0 0.6112176255198434 16 P35637,Q13501,Q13148,Q15165,Q92804 5 +Mitral stenosis 0.7642906829111207 1.770377331831798 0.0766643033724503 1.0 0.6112176255198434 5 O75844,Q04721 2 +Xerostomia 0.5431094011817429 1.7674516223763903 0.0771526241261737 1.0 0.6131563472881439 16 P35637,Q13501,Q13148,Q15165,Q92804 5 +Aplasia hypoplasia involving the femoral head and neck 0.5922131767279173 1.7673453668196066 0.0771704064875944 1.0 0.6131563472881439 11 O95831,Q8WVQ1,Q96L58,Q96HY6 4 +Very long chain fatty acid accumulation 0.6851267620387748 1.7649132031601371 0.0775783543504222 1.0 0.6141388621967133 7 O75381,P56589,P40855 3 +Elevated circulating long chain fatty acid concentration 0.9294964028776976 1.7632177137042702 0.0778637773166601 1.0 0.6141388621967133 2 P23786 1 +Action tremor 0.3708004788270826 1.7618646566378016 0.0780921673633339 1.0 0.6141388621967133 61 Q8IY17,P41440,Q14108,Q99720,P00846,P35637,O43681,Q9NR77,Q5T8D3,Q9Y5Y0,P31749,P20700 12 +Dysdiadochokinesis 0.5345325881052712 1.7605242478898229 0.0783189599166462 1.0 0.6141388621967133 17 Q9NW08,Q06787,P41440,O75503,Q13501,O75027,Q6DKK2,Q9UBB4,P20700 9 +Abnormal circulating bilirubin concentration 0.4678114140511351 1.7592493340504576 0.0785351681332691 1.0 0.6141388621967133 26 Q9UJS0,P36551,P41440,P23786,P40855,P55263 6 +Dyscalculia 0.5905952983807212 1.758029416636815 0.0787425042010365 1.0 0.6141388621967133 11 Q13148,P35637,P09651,Q13501,Q96L73,P22626 6 +Decreased pulmonary function 0.7607859357467548 1.754840069446689 0.0792866675959362 1.0 0.6173506138020814 5 P31749 1 +Abnormal circulating non proteinogenic amino acid concentration 0.6286073090777661 1.7477906137836037 0.0805002912231578 1.0 0.6216115203059737 9 P00846,P05067,Q9Y619 3 +Chronic lymphatic leukemia 0.8144327050211685 1.7443783139552425 0.0810931439072217 1.0 0.623094601619905 4 Q01130 1 +Chronic leukemia 0.8144327050211685 1.7443783139552425 0.0810931439072217 1.0 0.623094601619905 4 Q01130 1 +Upper limb postural tremor 0.9217266187050356 1.730995533605441 0.0834525610791492 1.0 0.6363184976100581 2 P20700 1 +Fasciculations 0.4144275762761666 1.7268939398303635 0.0841867130068874 1.0 0.6363184976100581 39 P51114,Q16637,P35637,Q9BQT8,Q13501,O95831,P22626 7 +Neoplasm of the male external genitalia 0.6090927355191905 1.720696368087954 0.0853059357857701 1.0 0.6376071867064617 10 Q13423,P31749 2 +Generalized hyperkeratosis 0.7061831776670267 1.715503338178768 0.0862529838927508 1.0 0.6397034569043075 6 O75844,P31749 2 +Reduced circulating prolactin concentration 0.7515046035492592 1.7136016784083874 0.0866019051018975 1.0 0.6397034569043075 5 P31749 1 +Progressive pulmonary function impairment 0.806268220663048 1.7101816407153725 0.0872322895778601 1.0 0.6397034569043075 4 P31749 1 +Ear pain 0.806268220663048 1.7101816407153725 0.0872322895778601 1.0 0.6397034569043075 4 P31749 1 +Hypothalamic hypothyroidism 0.806268220663048 1.7101816407153725 0.0872322895778601 1.0 0.6397034569043075 4 P31749 1 +Brain stem compression 0.806268220663048 1.7101816407153725 0.0872322895778601 1.0 0.6397034569043075 4 P31749 1 +Decreased circulating follicle stimulating hormone concentration 0.806268220663048 1.7101816407153725 0.0872322895778601 1.0 0.6397034569043075 4 P31749 1 +Intracranial meningioma 0.806268220663048 1.7101816407153725 0.0872322895778601 1.0 0.6397034569043075 4 P31749 1 +Neuralgia 0.806268220663048 1.7101816407153725 0.0872322895778601 1.0 0.6397034569043075 4 P31749 1 +Abnormality of the radioulnar joints 0.8052383270879759 1.705862096735263 0.0880337582633825 1.0 0.6404726162578157 4 Q8WVQ1 1 +Radioulnar dislocation 0.8052383270879759 1.705862096735263 0.0880337582633825 1.0 0.6404726162578157 4 Q8WVQ1 1 +Pseudoepiphyses of the metacarpals 0.7497485815771354 1.7057846350457886 0.0880481848883407 1.0 0.6404726162578157 5 P51812 1 +Upper limb asymmetry 0.8050092873916915 1.7049012905915897 0.0882128356473868 1.0 0.6404726162578157 4 P31749 1 +Central hypoventilation 0.6345401198975663 1.70428536311213 0.0883277881130617 1.0 0.6404726162578157 8 O95169,Q8N183 2 +Congenital hepatic fibrosis 0.6333893623484541 1.6982803089449288 0.0894548693618511 1.0 0.6458475397889683 8 Q15051,Q8IY17 2 +Metatarsus adductus 0.5440775971989708 1.6953769729763923 0.0900039313124787 1.0 0.6464420557264134 14 O96028,Q15392,Q03252,Q08J23 4 +Abnormal prolactin level 0.7013109073099661 1.6926277486482246 0.0905263458079024 1.0 0.6469162528868964 6 P31749 1 +Abnormal central sensory function 0.746739432259593 1.6923785285982464 0.0905738235709998 1.0 0.6469162528868964 5 Q969G3,P31749 2 +Abnormal circulating acetylcarnitine concentration 0.6676065736946133 1.6791399564791272 0.0931247706240792 1.0 0.6542656985962337 7 P23786 1 +Restlessness 0.4070347669462649 1.6770265297861615 0.0935372941489536 1.0 0.6560269773093529 40 Q9UJS0,P48449,P42892,P35637,P43243,P05067,Q13501,Q13148,Q6Y7W6,Q92804,Q15165 11 +Loss of subcutaneous adipose tissue in limbs 0.7947019867549776 1.6615980822175072 0.096593388147516 1.0 0.6653403940232928 4 Q03252,O75844,P02545 3 +Impaired vibration sensation in the lower limbs 0.5120895621961923 1.6611921099466649 0.0966748697033339 1.0 0.6653403940232928 18 O00400,P00846,Q9NR77,Q9Y5Y0,Q9H0B6 5 +High frequency sensorineural hearing impairment 0.7944413386984222 1.6605014351850342 0.0968136194208195 1.0 0.6653403940232928 4 O75844,Q9NWM8 2 +Pain in head and neck region 0.6632864549112344 1.657897010702602 0.0973382556437962 1.0 0.6653403940232928 7 Q15043,P31749 2 +Flattened epiphysis 0.7938150720612488 1.657866172887629 0.0973444812116333 1.0 0.6653403940232928 4 O95831 1 +Subcutaneous nodule 0.5033942040655445 1.657412703453973 0.097436064817018 1.0 0.6653403940232928 19 P25054,P35637,P48735,P31749,Q9NZ08 5 +Lower limb asymmetry 0.662855425705194 1.6557755982825824 0.0977672711598951 1.0 0.6653403940232928 7 P07437,P31749 2 +Limited elbow movement 0.4096315804640659 1.6551298885358956 0.0978981532548015 1.0 0.6653403940232928 38 P37268,Q96AY3 2 +Abnormal tongue physiology 0.502121279373221 1.6483786614596092 0.099274992010383 1.0 0.6653403940232928 19 O95831,Q16637,Q9BQT8 3 +Abnormality of the tonsils 0.6609771445108872 1.6465271096472454 0.0996552833990302 1.0 0.6653403940232928 7 P31751,P00813,Q13546 3 +Aplasia hypoplasia of the sternum 0.7364659673592752 1.6465099655770696 0.0996588100523441 1.0 0.6653403940232928 5 Q9Y619 1 +Abnormal brain positron emission tomography 0.6606692528086531 1.645010447893713 0.0999676565151679 1.0 0.6653403940232928 7 Q969G3,P31749 2 +Abnormality of circulating leptin level 0.7907233081811713 1.6448498681011474 0.1000007753452676 1.0 0.6653403940232928 4 P31751,O75844 2 +Abnormality of upper limb joint 0.318291050349873 1.6390826028197694 0.1011960577174251 1.0 0.667820762180335 123 P37268,Q96AY3,P42892,Q03164,Q9NR77,O94761,Q96L73,O95831,P06753,O60828,P25054,P02545,Q9Y619,P22681,O95155,Q9Y5Y0,P31749,Q15056,Q04721,Q8WVQ1,Q99567,Q15392,P23786,Q15233,O96028,P57740,Q15427,O75844,Q96L58 29 +Abnormal biliary tract morphology 0.460191603690416 1.6376638044411145 0.1014918451288293 1.0 0.667820762180335 24 Q14108,O43681,P09601,P21266,Q10713 5 +Prominent ear helix 0.7884731621914254 1.635370067536767 0.1019714932608844 1.0 0.6689100486199223 4 Q5T8D3,O75844 2 +Distal muscle weakness 0.3440397832708639 1.633382135431202 0.1023886518822705 1.0 0.6694946682304671 69 Q8IY17,P36551,P41440,Q99720,P00846,P35637,Q9NR77,Q9BQT8,Q13501,Q13148,O95831,Q9Y5Y0,P22626 13 +Thyroiditis 0.6072749037290985 1.6332588089882485 0.102414576049036 1.0 0.6694946682304671 9 P00813 1 +Abnormal autonomic nervous system physiology 0.4114383617983652 1.6316152262565655 0.102760568603885 1.0 0.6699201199031597 36 P41440,P0DP25,P42892,Q15067,O43681,P20700 6 +Increased connective tissue 0.6578715862786266 1.6312211942053627 0.1028436547707252 1.0 0.6699201199031597 7 P31751,O95831,P02545 3 +Acquired abnormal hair pattern 0.6576602674944299 1.6301790510054548 0.1030636601326213 1.0 0.6704168910161032 7 P25054,P02545,P04150,O75844,O60828 5 +Schistocytosis 0.7859887193558828 1.6248967438160544 0.1041845621463535 1.0 0.6721302989732166 4 Q05682,P41440 2 +Horizontal pendular nystagmus 0.9249688295912436 1.6247626206153003 0.1042131485636881 1.0 0.6721302989732166 3 P00846 1 +Slow decrease in visual acuity 0.5674977940233127 1.6242415117550584 0.1043242745032846 1.0 0.6721302989732166 11 P00846,P31749 2 +Contractures of the joints of the lower limbs 0.3676899617407867 1.6230950303801246 0.1045690918152009 1.0 0.6721302989732166 57 P37268,Q96AY3,Q99720,P35637,P23786,P49902 6 +Echolalia 0.5369073144152858 1.6174199226395374 0.1057876681413518 1.0 0.6735888966643795 13 Q9UJS0,Q9UHX1,P53701,Q13501 4 +Velopharyngeal insufficiency 0.685189413679393 1.6166423201980331 0.1059555111813828 1.0 0.6735888966643795 6 Q8WYQ5,Q9BUF5,Q96DF8,Q15427 4 +Abnormal size of pituitary gland 0.7290899442995317 1.6134869093419886 0.1066387650247853 1.0 0.67576521749402 5 P31749 1 +Muscle fibrillation 0.5047481738904939 1.610336152369805 0.1073244908858237 1.0 0.6773678680741402 18 O95831,Q16637,Q9BQT8 3 +Upper limb spasticity 0.6152800401471382 1.6034017830470084 0.1088459776418637 1.0 0.6823355372602857 8 Q99720,P35637,Q12768 3 +Increased circulating acth level 0.7806211430880942 1.6022469044509515 0.1091010216986347 1.0 0.6829975865294945 4 P04150 1 +Myositis 0.6012892807896173 1.6009368422024743 0.1093909084771724 1.0 0.6829975865294945 9 Q9NZ08,P22626,P28070 3 +T lymphocytopenia 0.5620249518969574 1.5923364312729171 0.111309131276031 1.0 0.6867007781367841 11 O95394,Q13432,P00813,Q13546 4 +Abnormal tricuspid valve morphology 0.537143385999721 1.589899154439169 0.1118575382992679 1.0 0.6891724684647101 12 P21964,P53701,P51812,Q12768 4 +Abnormality of skull ossification 0.5267848750346529 1.585666216999011 0.1128150465287045 1.0 0.6915601181098016 14 Q04721,O75718,P02545,Q32P28,O75844 5 +Short lingual frenulum 0.7766721983506668 1.5855643203338845 0.11283817536054 1.0 0.6915601181098016 4 O75844,P02545 2 +Annular pancreas 0.7214601816280247 1.5792522009011714 0.1142782208420258 1.0 0.693388258554657 5 O95155,Q9BXW9 2 +Distal upper limb amyotrophy 0.5592299083637241 1.5760139208131447 0.1150225950613772 1.0 0.693388258554657 11 Q9NR77,Q9BQT8,Q13501 3 +Abnormal sarcomere morphology 0.8834532374100712 1.5716971044893904 0.1160208140246226 1.0 0.693388258554657 2 P51114 1 +Abnormal z disc morphology 0.8834532374100712 1.5716971044893904 0.1160208140246226 1.0 0.693388258554657 2 P51114 1 +Thin ribs 0.5245665518678955 1.571529400506543 0.1160597307828161 1.0 0.693388258554657 14 P02545,Q9Y619,Q32P28,O95831,O75844 5 +Ureteral duplication 0.5953881392791992 1.5689966724921904 0.1166487143622647 1.0 0.6957156058639422 9 O75844,P02545,P23786 3 +Limited hip movement 0.5182990665356141 1.5658845029549016 0.1173756584741954 1.0 0.6975739272998804 15 Q96AY3,Q7LGA3,P02545,P06753,Q96L73,O75844 6 +Generalized limb muscle atrophy 0.5806479530428803 1.5629516654209257 0.1180639640361178 1.0 0.6987948328229108 10 P06753,Q8IY17 2 +Axial dystonia 0.9078018884680364 1.5585605096380457 0.1191004358794458 1.0 0.7008663000214924 3 P35637 1 +Abnormal chorioretinal morphology 0.4127593930190066 1.5581116461539029 0.119206784417053 1.0 0.7008663000214924 33 Q8IY17,Q9Y619,O75381,P56589,P04439,P40855,P53701,P31749,Q9H9S5,Q10713 10 +Chromosomal breakage induced by ionizing radiation 0.716155784207183 1.5554083228179552 0.119848853187112 1.0 0.7008663000214924 5 P31749 1 +Posterior polar cataract 0.8794244604316539 1.5548863828392756 0.1199731310162484 1.0 0.7008663000214924 2 P08670 1 +Abnormal sternal ossification 0.7159522460451659 1.55449271675678 0.1200669326151742 1.0 0.7008663000214924 5 Q9Y619 1 +Truncal titubation 0.7689237767919415 1.5527860315666762 0.1204742608969082 1.0 0.7012853214228854 4 Q9Y5Y0 1 +Atrophic scars 0.6417875326265409 1.5516743567214804 0.1207401614713929 1.0 0.7012853214228854 7 Q9NWM8,Q8NCH0 2 +Furrowed tongue 0.640513430840677 1.5453541795957302 0.122260617013326 1.0 0.7060860831791118 7 P31749 1 +Calvarial hyperostosis 0.6690479820691241 1.5401405298281103 0.1235261022714584 1.0 0.7060860831791118 6 P31749,P22626 2 +Anaphylactic shock 0.8756834532374091 1.5392714914015415 0.1237380307250197 1.0 0.7060860831791118 2 Q01130 1 +Elevated total serum tryptase 0.8756834532374091 1.5392714914015415 0.1237380307250197 1.0 0.7060860831791118 2 Q01130 1 +Exanthem 0.8756834532374091 1.5392714914015415 0.1237380307250197 1.0 0.7060860831791118 2 Q01130 1 +Increased proportion of cd25 mast cells 0.8756834532374091 1.5392714914015415 0.1237380307250197 1.0 0.7060860831791118 2 Q01130 1 +Abnormal mast cell morphology 0.8756834532374091 1.5392714914015415 0.1237380307250197 1.0 0.7060860831791118 2 Q01130 1 +Short palpebral fissure 0.4157004728245985 1.53807937075921 0.1240292093003074 1.0 0.7060860831791118 32 P07437,Q9UHX1,P02545,Q9Y619,O75844,P55795,Q03164,Q9BXW9,P98175 9 +Profound global developmental delay 0.5241291125938269 1.5374957815954688 0.1241719472744098 1.0 0.7060860831791118 13 P37268,O75381,P56589 3 +Abnormality of circulating glucocorticoid level 0.5188672096784326 1.5351477495397714 0.1247475395236297 1.0 0.7060860831791118 14 Q969G3,Q13423,P31749 3 +Intellectual disability progressive 0.500936434459125 1.5336325687593158 0.1251200712607523 1.0 0.7064891190800833 17 O95831,O95721,Q15067,P53701 4 +Inverted nipples 0.5883651358610403 1.5308925981448518 0.1257959388826841 1.0 0.7077349323870191 9 Q15067,P56589 2 +Retinal dysplasia 0.6005986410974921 1.5259962600836632 0.1270107958978559 1.0 0.7077399666279569 8 P07437,P53701,Q10713 3 +Hypoventilation 0.5115579170333636 1.5219802312394313 0.1280140341440465 1.0 0.710782684818849 15 O95169,Q8N183,P06753,P61978 4 +Serositis 0.4580455542045478 1.5184886808404736 0.1288912508575603 1.0 0.713106517200073 22 Q14C86,O15460,P57740,P14174,Q8NFH4,Q9NZ08,Q8N1F7 7 +Brushfield spots 0.7590089906910855 1.5107632570764122 0.130848779204511 1.0 0.7192490954824671 4 O75381,P56589 2 +Elevated mean arterial pressure 0.8679136690647469 1.506828063489127 0.1318547342413174 1.0 0.7192490954824671 2 P42892 1 +Elevated diastolic blood pressure 0.8679136690647469 1.506828063489127 0.1318547342413174 1.0 0.7192490954824671 2 P42892 1 +Elevated systolic blood pressure 0.8679136690647469 1.506828063489127 0.1318547342413174 1.0 0.7192490954824671 2 P42892 1 +Retinal arteriolar tortuosity 0.5700283546313649 1.503596982313828 0.132685168625035 1.0 0.7192490954824671 10 P21964,P00846 2 +Duplication of the distal phalanx of hand 0.8667625899280568 1.5020204551226772 0.1330918261957778 1.0 0.7192490954824671 2 Q8WVQ1 1 +Ketotic hypoglycemia 0.8931404909228466 1.5019027158637697 0.1331222351421963 1.0 0.7192490954824671 3 Q13423 1 +Hypoglycemic coma 0.5829853755456412 1.501640134003238 0.1331900724853738 1.0 0.7192490954824671 9 P31751,Q13423,Q16134 3 +Patchy changes of bone mineral density 0.75681471222613 1.5014517822683315 0.1332387491457516 1.0 0.7192490954824671 4 Q13126 1 +Incomplete penetrance 0.4114678929044953 1.4986644150940691 0.1339607127056059 1.0 0.7223037734785505 32 O60313,Q06787,P36551,Q969G3,P00846,P49792,O95453,P11166,Q92733,Q9UBB4,O14979,Q6UWE0 12 +Osteolysis involving bones of the feet 0.6597158062250583 1.4957360581869052 0.1347224498786037 1.0 0.723900352803926 6 O75844,Q04721,P02545 3 +Foot acroosteolysis 0.6597158062250583 1.4957360581869052 0.1347224498786037 1.0 0.723900352803926 6 O75844,Q04721,P02545 3 +Round face 0.4540618209987199 1.48745442677747 0.1368948311870885 1.0 0.7313602435928763 22 Q8WVQ1,P02545,O75718,Q32P28,Q03164,Q69YQ0,P31749 7 +Fatigable weakness of respiratory muscles 0.5055431130265018 1.482706049337689 0.1381525267035224 1.0 0.735551808841585 15 P35637,Q13501,Q13148,Q15165,Q92804 5 +Tetraplegia tetraparesis 0.3656810177641899 1.479007271173023 0.1391383714867946 1.0 0.7380338786202877 50 Q13423,O95630,P00846,P35637,O43681,Q13501,Q13148,O95831,Q9H9P8,P37198,P20700 11 +Short nail 0.655292909169713 1.474650000916794 0.1403066647621198 1.0 0.7387187007326561 6 O75844,Q04721,Q96L58 3 +Abnormal metatarsal morphology 0.4262504959185388 1.474003087107841 0.1404807599763555 1.0 0.7387187007326561 28 O96028,Q8WVQ1,Q08J23,Q15392,Q03252,P31749,Q9H9S5 7 +Decreased light and dark adapted electroretinogram amplitude 0.8857251649621856 1.4732145703678396 0.1406931874912937 1.0 0.7387187007326561 3 Q15067 1 +Multiple joint contractures 0.442755601706422 1.472714163982923 0.1408281257302048 1.0 0.7387187007326561 23 P41440,Q99567,Q15043,Q96L58,Q9Y3Z3,O75844,Q9H9S5,Q9H0B6 8 +Thin clavicles 0.7498718440054142 1.471964859439372 0.1410303671956256 1.0 0.7387187007326561 4 O75844 1 +Heterogeneous 0.3739876797746985 1.4707624035888418 0.1413553832359757 1.0 0.7387187007326561 45 Q9BQE5,Q9Y619,O75844,P00846,Q15051,P05067,Q9NR77,P06753,P31749,Q9HCC0,P00367 11 +Abnormal circulating androgen level 0.5035564867506689 1.4697146107255434 0.1416390639224889 1.0 0.7387187007326561 15 Q969G3,Q13423,P31749 3 +Arterial thrombosis 0.6252878587207038 1.4696318592955646 0.141661486765884 1.0 0.7387187007326561 7 P31749,Q9NZ08 2 +Abnormality of the phalanges of the toes 0.4766152178333745 1.466189533569917 0.1425966591834591 1.0 0.7387187007326561 19 Q04721,Q8WVQ1,P02545,O75431,P38398,Q9BXW9,O75844 7 +Abnormal intraocular pressure 0.6535030719780813 1.4661099013653642 0.1426183487153212 1.0 0.7387187007326561 6 Q15043,Q8NCH0 2 +Membranoproliferative glomerulonephritis 0.8572661870503588 1.462350032500519 0.1436453145913747 1.0 0.7387187007326561 2 O95394 1 +Extra axial cerebrospinal fluid accumulation 0.8572661870503588 1.462350032500519 0.1436453145913747 1.0 0.7387187007326561 2 P20700 1 +Proximal muscle weakness 0.3388285655184712 1.4623061063221217 0.1436573459615178 1.0 0.7387187007326561 65 P51114,Q16637,Q13126,P36551,Q99720,P00846,P35637,Q5T8D3,Q9BQT8,Q13501,Q13148,P06753,P22626 13 +Parkinsonism 0.4025357579601869 1.4610015530468878 0.1440150152242767 1.0 0.7397423248965052 33 Q13148,Q15043,Q99720,P35637,Q6Y7W6,Q13501,P05067 7 +Abnormal choroid morphology 0.3954664514123441 1.4572412204383294 0.1450498058529707 1.0 0.7409773214657784 35 Q8IY17,Q9Y619,O75381,P56589,P04439,P40855,P53701,P31749,Q9H9S5,Q10713 10 +Spinal canal stenosis 0.5871506815497345 1.4547557171011494 0.1457369015869571 1.0 0.7436727669601404 8 P31749 1 +Phalangeal dislocation 0.8541007194244593 1.449124741971962 0.1473027495799357 1.0 0.7483878257525275 2 Q8WVQ1 1 +Atlantoaxial dislocation 0.8541007194244595 1.449124741971962 0.1473027495799357 1.0 0.7483878257525275 2 Q8NCH0 1 +Advanced ossification of carpal bones 0.8541007194244593 1.449124741971962 0.1473027495799357 1.0 0.7483878257525275 2 Q8WVQ1 1 +Hypotension 0.4228196371653123 1.444159024527328 0.1486942480303896 1.0 0.7516707883679592 28 Q13423,O43772,P35610,P49366,O43681,P22681,Q6Y7W6,Q01130,P20700 9 +Anarthria 0.6479074557529991 1.4393855894606598 0.1500413049651516 1.0 0.7524407155249259 6 P35637 1 +Limb pain 0.5583236417450048 1.4379266635622878 0.1504548633804914 1.0 0.7524407155249259 10 P00846 1 +Tremor by anatomical site 0.4292056911614389 1.43698997186695 0.1507208429961697 1.0 0.7524407155249259 26 Q99720,Q16637,P35637,P20700 4 +Muscle stiffness 0.4725461447372302 1.4369402621255405 0.1507349684045973 1.0 0.7524407155249259 19 P00846,Q15392,P23786,P53985,Q9Y3Z3 5 +Protrusio acetabuli 0.8763289198372861 1.4368394937695526 0.1507636056101198 1.0 0.7524407155249259 3 Q96AY3 1 +Toe walking 0.4321104417897781 1.434001896339058 0.1515717216930312 1.0 0.7535445921703848 25 P02545,Q99720,P35637,O43681,O95831,P06753,Q9H9S5 7 +Cutaneous finger syndactyly 0.7408111376519408 1.4334319929873378 0.1517344209278182 1.0 0.7535445921703848 4 Q9Y619 1 +Mitral valve calcification 0.7394739677625239 1.4277409224856716 0.1533664427387739 1.0 0.7562542813386364 4 O75844,P02545 2 +Cardiac valve calcification 0.7394739677625239 1.4277409224856716 0.1533664427387739 1.0 0.7562542813386364 4 O75844,P02545 2 +Thoracic kyphoscoliosis 0.6454536746605033 1.427654951208373 0.1533911985734026 1.0 0.7562542813386364 6 O75844 1 +Diffuse mesangial sclerosis 0.4545723091086147 1.4231205458808125 0.1547012132751031 1.0 0.7611038594040939 21 Q14C86,Q9Y2Z9,Q8NFH4,P00813,Q8N1F7 5 +Male reproductive system neoplasm 0.4960342157886504 1.42044135380252 0.1554792307482047 1.0 0.763321191799607 15 Q13423,P25054,P31749,Q01844 4 +Multifocal cerebral white matter abnormalities 0.6850235903392572 1.4148472213831156 0.1571132954078837 1.0 0.7662842096993921 5 Q9Y619 1 +Neurodegeneration 0.415543869506749 1.4147606461448874 0.157138686220591 1.0 0.7662842096993921 29 P35637,Q9Y3Z3,Q13501,Q13148,Q6DKK2,Q92804,Q15165 7 +Progeroid facial appearance 0.5670029871650439 1.4144396851010506 0.1572328449147337 1.0 0.7662842096993921 9 Q03252,O75844,Q14191,P02545 4 +Syncope 0.4940673683052275 1.407537870352658 0.1592679558532683 1.0 0.7681310959924597 15 P02545,P0DP25,Q969G3,Q01130,P31749 5 +Retrocollis 0.867795036414665 1.4037869878281692 0.1603822898780929 1.0 0.7681310959924597 3 P35637 1 +Tachycardia 0.4218058192513131 1.4034829862873737 0.1604728619431177 1.0 0.7681310959924597 27 O43772,P0DP25,P42892,P23786,Q01130 5 +Abnormal epiphyseal ossification 0.4818316240499755 1.4030960365770797 0.1605882029091856 1.0 0.7681310959924597 17 O00116,O75381,P56589,P40855,Q96L58 5 +Patchy alopecia 0.8423021582733803 1.3998325021854463 0.1615634823952667 1.0 0.7681310959924597 2 O75844 1 +Aplasia hypoplasia of the colon 0.8423021582733803 1.3998325021854463 0.1615634823952667 1.0 0.7681310959924597 2 O75844 1 +Epidermal hyperkeratosis 0.8423021582733803 1.3998325021854463 0.1615634823952667 1.0 0.7681310959924597 2 O75844 1 +Stiff skin 0.8423021582733803 1.3998325021854463 0.1615634823952667 1.0 0.7681310959924597 2 O75844 1 +Prominent umbilicus 0.8423021582733803 1.3998325021854463 0.1615634823952667 1.0 0.7681310959924597 2 O75844 1 +Second degree atrioventricular block 0.8423021582733803 1.3998325021854463 0.1615634823952667 1.0 0.7681310959924597 2 P0DP25 1 +Xanthomatosis 0.84230215827338 1.3998325021854456 0.1615634823952669 1.0 0.7681310959924597 2 P34913 1 +Exercise induced muscle cramps 0.6816319228085305 1.3994800944263948 0.1616690634223316 1.0 0.7681310959924597 5 P23786 1 +Hyperlipidemia 0.396007032104825 1.3987220752286904 0.1618963417682071 1.0 0.7681310959924597 33 P31751,P28070,P22830,P23786,O75844 5 +Aplasia hypoplasia of the femur 0.4871504788407483 1.3967129360444446 0.1624999125612216 1.0 0.7681310959924597 16 Q9UHX1,Q8WVQ1,O00116,O95831,Q96L58,Q96HY6 6 +Abnormal waist to hip ratio 0.6103439623110238 1.3949956829104402 0.1630171414054704 1.0 0.7681310959924597 7 P31751,P18031,O00330 3 +Cupped ribs 0.6099562732611502 1.3930557718548982 0.1636029261162428 1.0 0.7681310959924597 7 O95831 1 +Atlantoaxial abnormality 0.7307670785013448 1.3906596820301964 0.1643286490830027 1.0 0.7681310959924597 4 Q9NWM8,Q8NCH0 2 +Abnormality of salivation 0.3589611986610533 1.3891264217365276 0.1647943106172658 1.0 0.7681310959924597 49 P51812,P55795,P35637,P43243,Q8N0X7,P42356,Q9NR77,Q03252,Q13501,Q13148,Q15165,Q92804,Q15233 13 +Aplasia hypoplasia involving the pelvis 0.4796631502042873 1.3882248893205382 0.1650685755756376 1.0 0.7681310959924597 17 O96028,Q8WVQ1,O95831,Q96L58,Q96HY6 5 +Increased susceptibility to fractures 0.3434545748000903 1.3871105898233718 0.1654080433597426 1.0 0.7681310959924597 60 O75845,Q96AY3,Q13126,Q04721,O75718,Q14108,P48735,Q9Y2U8,P22681,Q13501,Q01130,P06753,Q96L58,P22626 14 +Vitritis 0.7298443778908081 1.3867278091938249 0.1655247774104169 1.0 0.7681310959924597 4 P53701 1 +Negativism 0.8388489208633081 1.3854084959853086 0.1659275946003173 1.0 0.7681310959924597 2 Q9BQE5 1 +Vertebral compression fracture 0.4792214825859068 1.3851947956192947 0.1659929116564857 1.0 0.7681310959924597 17 Q96AY3,Q04721,O75718,Q32P28,Q14108 5 +Recurrent fractures 0.4037498847079309 1.3842709768615091 0.1662754973938631 1.0 0.7681310959924597 31 Q96AY3,Q13126,Q04721,O75718,P48735,Q9Y2U8,Q13501,Q96L58 8 +Abnormal circulating ige level 0.6363258542655494 1.3839613142851432 0.1663703005916037 1.0 0.7681310959924597 6 O95394,P00813 2 +Spondyloepimetaphyseal dysplasia 0.5612176161698954 1.382777672186848 0.1667330472250903 1.0 0.7681310959924597 9 O95831,Q96L58 2 +Abnormal eosinophil morphology 0.5596500362269181 1.374190877952027 0.1693824319498111 1.0 0.7681310959924597 9 P00813,Q01130 2 +Posteriorly rotated ears 0.3073579623950148 1.374122692774571 0.1694035955432329 1.0 0.7681310959924597 119 P37268,Q9UHX1,P42892,P98175,Q10713,Q4J6C6,P07437,Q9Y619,Q08J23,P22681,O95155,Q8NCH0,Q9H9S5,Q8WVQ1,O75381,Q15392,P23786,O96028,Q8IY17,P56589,P40855 21 +Abnormal hypothalamus physiology 0.5714832690949166 1.3714123107081315 0.1702464619729053 1.0 0.7693188759874378 8 P31749 1 +Abnormality of the anterior fontanelle 0.3879801497976687 1.3691369195735812 0.1709564796166842 1.0 0.7693188759874378 34 P51812,O75718,Q9Y619,O75381,Q16134,P56589,P40855 7 +Dementia 0.3401650701987941 1.3688333031198023 0.1710513881644453 1.0 0.7693188759874378 61 Q8IY17,Q14108,P00846,Q9NQZ5,P35637,P27544,O43681,Q13501,Q13148,Q6Y7W6,P05067,P22626,P20700 13 +Decreased circulating aldosterone level 0.8575572166603396 1.3641250932201894 0.1725281984077393 1.0 0.7707581584039238 3 Q13423 1 +Abdominal pain 0.3242568145592526 1.3618883382545346 0.173233127057061 1.0 0.7715021788004601 90 P42892,Q14C86,Q13423,P25054,P22681,Q8NFH4,Q15056,Q6UN15,Q01844,Q14108,P35637,P23786,O15460,Q01130,Q9UER7,Q8N1F7,P36551,Q70HW3,Q13546,P57740,Q14566,P14174,Q9NZ08 23 +Calcinosis 0.6308231432371356 1.357581263839275 0.1745965914691885 1.0 0.7718968631778279 6 O75844,P02545 2 +Open mouth 0.39638360104521 1.3575251028069657 0.1746144227892625 1.0 0.7718968631778279 32 P51812,Q96JM3,Q86XL3,Q8WYQ5,P31749,P61978 6 +Abnormality on pulmonary function testing 0.4372246089690241 1.355733537630532 0.1751839645565802 1.0 0.7718968631778279 22 Q969G3,O95453,Q96L58,Q9BQT8,P06753,P31749,Q9H9S5 7 +Peroneal muscle atrophy 0.6719539155990223 1.355586074733876 0.175230904946122 1.0 0.7718968631778279 5 Q9NR77,Q12768 2 +Progressive visual loss 0.4122610312589907 1.352043714062381 0.1763613315193171 1.0 0.7718968631778279 28 Q8IY17,P00846,P31749,O75503,Q15051,P50897 6 +Vertebral wedging 0.8543113628849165 1.3515501161490997 0.1765192774006183 1.0 0.7718968631778279 3 Q96AY3 1 +Abnormal circulating citrulline concentration 0.6290411829016928 1.3490328369567612 0.177326419099884 1.0 0.7718968631778279 6 P00846,Q9Y619 2 +Muscle fiber atrophy 0.4525122230672277 1.3466521532141842 0.1780922888809191 1.0 0.7718968631778279 20 Q99720,P35637,P23786,P61978,P06753,P22626 6 +Ambiguous genitalia male 0.8527437725927636 1.3454771838274358 0.1784711846003284 1.0 0.7718968631778279 3 Q15392 1 +Disproportionate short stature 0.414922318367302 1.3443492104498838 0.1788354893590709 1.0 0.7718968631778279 27 Q9UHX1,O75718,O00116,Q32P28,Q8WVQ1,O15228,Q03164,Q15392,P16278,Q96HY6 10 +Widely patent fontanelles and sutures 0.7194113447985668 1.3422457293451266 0.1795163336753606 1.0 0.7718968631778279 4 P98175,O75844 2 +Fetal akinesia sequence 0.6688789029458241 1.3416275148787684 0.1797168001735425 1.0 0.7718968631778279 5 P06753 1 +Delayed closure of the anterior fontanelle 0.4963313131308013 1.3374949978743351 0.1810611139753839 1.0 0.7718968631778279 12 O75381,P51812 2 +Female pseudohermaphroditism 0.8270503597122288 1.3361494457630465 0.1815004311210915 1.0 0.7718968631778279 2 P04150 1 +Pain 0.2987960780835164 1.335996964238486 0.1815502655596246 1.0 0.7718968631778279 190 P28070,P00846,P42892,Q14C86,Q9NR77,Q13501,Q13148,P22626,P20700,Q13423,P25054,P02545,P21964,P22681,Q9Y5Y0,Q8NFH4,P31749,Q96HY6,Q9H9S5,Q04721,Q6UN15,Q01844,Q14108,Q15043,P35637,P48735,P23786,O15460,Q9Y2U8,Q01130,Q92804,P43243,Q8N1F7,P36551,Q70HW3,Q13546,Q969G3,Q14566,Q03252,P14174,Q15165,O75844,Q9NZ08 43 +Mutism 0.4717277544964556 1.3337271297679456 0.1822933001957973 1.0 0.7718968631778279 17 P53701,P22626,P35637,Q13501 4 +Hepatic encephalopathy 0.6670931295815761 1.33351896903672 0.1823615547361643 1.0 0.7718968631778279 5 Q6NUQ1,Q9UJS0 2 +Generalized muscle weakness 0.3828694581517868 1.3331949845627782 0.1824678248218492 1.0 0.7718968631778279 35 P35637,Q15165,Q13501,Q13148,O95831,Q92804,P06753,Q9H9S5 8 +Tissue ischemia 0.4500941063605601 1.3287131906289071 0.1839426114188107 1.0 0.7718968631778279 20 P02545,O15460,O75844,P05067,Q9NZ08 5 +Intestinal hypoplasia 0.716171915226453 1.3284267736187143 0.1840371594883671 1.0 0.7718968631778279 4 O75844,Q99567 2 +Cone shaped epiphysis 0.4863868167005346 1.326384020522994 0.1847125290025371 1.0 0.7727394641297186 14 O95831 1 +Babinski sign 0.3202685903499426 1.3253843780186088 0.1850436957255363 1.0 0.7727394641297186 95 Q8IY17,P51812,O00400,P41440,Q99720,P00846,Q15043,P35637,Q15067,P49902,O43681,Q9NR77,Q6DKK2,Q13501,O95831,P37198,P20700 17 +Macroorchidism 0.6240735948753554 1.3251889325334978 0.1851084952186648 1.0 0.7727394641297186 6 P38159 1 +Malabsorption 0.3435241288026788 1.323857680652114 0.1855503153033151 1.0 0.7727394641297186 57 P25054,Q08J23,O75381,P56589,P22681,Q14566,P14174,P40855,Q01130,P09601,P21266,Q9NZ08 12 +Ventricular arrhythmia 0.3748698398705645 1.3228211226279298 0.1858948710878096 1.0 0.7727394641297186 39 O43772,P00846,P42892,P23786,Q01130 5 +Vascular tortuosity 0.713818424922504 1.3183854744699783 0.1873746407949519 1.0 0.7734563317016576 4 P00846 1 +Multiple prenatal fractures 0.5950185248571598 1.3181937737024425 0.1874387892839049 1.0 0.7734563317016576 7 P06753,O75718 2 +Asymmetric growth 0.4931612921574973 1.317762157358208 0.1875832796443886 1.0 0.7734563317016576 12 P31751,P07437,P31749 3 +Low set posteriorly rotated ears 0.3225986186428624 1.316579700182293 0.1879795469379166 1.0 0.7734563317016576 81 P37268,O96028,Q4J6C6,Q8IY17,Q8WVQ1,P07437,Q08J23,O75381,Q15392,P56589,P22681,P40855,Q8NCH0,P98175,Q10713 15 +Postural tremor 0.440491887330652 1.3158643046462872 0.1882195913772528 1.0 0.7734563317016576 21 Q9NR77,P00846,P35637,P20700 4 +Meningitis 0.5606449762387278 1.31358311727291 0.18898653320255 1.0 0.7734563317016576 8 Q9NZ08 1 +Neonatal hypoglycemia 0.4924704331268467 1.31345997170784 0.1890280005510898 1.0 0.7734563317016576 12 P31751,O43772,Q9UKG1,O00330,Q96L73 5 +Eyelid myoclonus 0.5143511851767154 1.3117503638373076 0.1896043775046345 1.0 0.7734563317016576 11 Q01105,P00374 2 +Neurofibromas 0.5936971615273396 1.3115619722155198 0.1896679709616331 1.0 0.7734563317016576 7 P31749 1 +Impaired glucose tolerance 0.6620157644343088 1.3104563515810184 0.1900415009491207 1.0 0.7734563317016576 5 Q9UKG1,P02545 2 +Nephrotic syndrome 0.3997751850012173 1.3094586207771512 0.190379045624679 1.0 0.7734563317016576 30 Q14108,O95721,Q07021,Q8NCH0,P00813,Q9Y2Z9 6 +Abnormality of the temporomandibular joint 0.7108730544401374 1.305817312726853 0.1916146910993321 1.0 0.7751348004073286 4 O75844 1 +Foot oligodactyly 0.8192805755395671 1.3037398147225392 0.1923223093749835 1.0 0.7751348004073286 2 P25054 1 +Distal lower limb amyotrophy 0.4822832705792986 1.299875087869668 0.1936437846791392 1.0 0.7751348004073286 14 Q15120,P02545,Q8TD16,Q9NR77,P06753,Q9H0B6 6 +Abnormality of fontanelles 0.3512697148425192 1.299873161729655 0.193644444946974 1.0 0.7751348004073286 49 P51812,O75718,P02545,Q32P28,Q9Y619,O15228,Q08J23,Q16134,O75381,P56589,O75844,O94761,P40855,Q8NCH0,P98175 15 +Premature arteriosclerosis 0.8172661870503584 1.2953423691346946 0.1952021492951146 1.0 0.7751348004073286 2 P02545 1 +Microcytic anemia 0.532400885924271 1.291737151115968 0.1964481870267516 1.0 0.7751348004073286 10 P22830 1 +Abnormality of facial adipose tissue 0.7072421777277307 1.290322235285569 0.1969387998125809 1.0 0.7751348004073286 4 Q03252,O75844 2 +Epispadias 0.6569244551178499 1.2873202514233435 0.1979826877608355 1.0 0.7766116532519232 5 P53701 1 +Bilateral single transverse palmar creases 0.475252798628227 1.2837631392544386 0.1992248446475715 1.0 0.7769652337525476 15 O75381,Q8IY17,P56589 3 +Rhizomelia 0.5092141533566156 1.2813038086165165 0.2000869756615502 1.0 0.7769652337525476 11 O15228,O75718,Q15392,O00116 4 +Eeg with frontal epileptiform discharges 0.8132374100719411 1.2785547655119534 0.2010538876985821 1.0 0.7769652337525476 2 P42356 1 +Pericarditis 0.6546706609841055 1.277075918380709 0.2015754458513448 1.0 0.7769652337525476 5 O15460,Q9NZ08 2 +Episodic vomiting 0.4787026970354671 1.2767280479647345 0.2016982756143086 1.0 0.7769652337525476 14 P00846,P22695,Q9Y619,P61978 4 +Airway obstruction 0.4691108068649157 1.275576129023454 0.2021053968758335 1.0 0.7769652337525476 16 P57076,P25054,P02545,P21964,P09601,O75844 6 +Chondrosarcoma 0.8340501541657397 1.2730854000806984 0.2029877391569909 1.0 0.7769652337525476 3 Q92804 1 +Nevus 0.3828089473094599 1.2723164799595947 0.2032606955122728 1.0 0.7769652337525476 33 Q96AY3,Q15056,Q9UHX1,Q9Y2U8,P22681,P31749 6 +Cogwheel rigidity 0.6129945387647708 1.2719506718911051 0.2033906462614416 1.0 0.7769652337525476 6 P00846 1 +Visual loss 0.339352840524721 1.2718363611516676 0.2034312667512232 1.0 0.7769652337525476 57 Q8IY17,P48449,P00846,Q15051,O75503,O15460,Q9Y5Y0,P53701,P31749,P50897,Q10713 11 +Delayed epiphyseal ossification 0.7021740769628252 1.2686918700687615 0.2045509832169547 1.0 0.7769652337525476 4 Q96L58 1 +Dysmetria 0.3305774233688979 1.268596431704963 0.2045850376525311 1.0 0.7769652337525476 62 O60313,Q9NW08,Q5JRX3,P42356,Q13501,Q10713,Q12768,P20700,P41440,Q8N183,Q9UBB4,Q15056,Q06787,Q96D71,Q14671,O75503,O75027,Q99700,Q8IV08,Q8N0X7,Q6P4A7,Q5T8D3,O75787,Q6DKK2 24 +Abnormal iris pigmentation 0.4259430848865755 1.267081451452669 0.2051261671394817 1.0 0.7769652337525476 22 Q8IY17,O75381,P56589,O95155,P40855,P31749 6 +Muscle spasm 0.3322909409095484 1.266667141873708 0.2052743336747649 1.0 0.7769652337525476 61 Q13148,Q16637,P00846,P35637,Q15165,P23786,P53985,Q9NR77,Q13501,Q9Y5Y0,Q6Y7W6,Q92804,Q9H9S5 13 +Hypersplenism 0.5277049741785899 1.265173932782574 0.2058089846414641 1.0 0.7769652337525476 10 Q14108,Q01130 2 +Vascular skin abnormality 0.2940854769641375 1.2639815871922393 0.2062366358618403 1.0 0.7769652337525476 126 Q13126,P22830,P00846,P02545,Q08J23,Q9BXW9,P21964,P22681,O95155,Q9Y3Z3,Q8NCH0,Q06136,P31749,P51812,Q6UN15,Q14108,O95394,Q16625,Q01130,P98194,P53701,Q9UER7,O95453,Q5T2R2,Q96L58,Q9NWM8,Q15427,O75844,Q14191 29 +Neck flexor weakness 0.7009978518241229 1.2636717263437234 0.2063478773115461 1.0 0.7769652337525476 4 P35637 1 +Abnormality of corneal stroma 0.4721154455359948 1.2630763154030844 0.2065617548330034 1.0 0.7769652337525476 15 O75845,Q16625,P34913,Q9Y5Z9 4 +Misalignment of incisors 0.6514976958525387 1.2626515644845728 0.2067144279139423 1.0 0.7769652337525476 5 Q8WVM7,Q8WXI9,Q99496,Q9BSJ2 4 +Flared iliac wing 0.5837363877046334 1.261530838755637 0.2071176563759205 1.0 0.7769652337525476 7 O95831,Q96L58 2 +Abnormal circulating cholesterol concentration 0.3765548792978195 1.2574113247175662 0.2086047305731841 1.0 0.7769652337525476 34 P37268,O75845,Q9UJS0,P50402,Q15904,P02545,Q15392,O75431,Q8N511,P57740,Q7Z5J4,P34913,Q9NVI7 13 +Symphalangism of middle phalanx of finger 0.8077697841726604 1.2557890658599995 0.2091924569529073 1.0 0.7769652337525476 2 Q15233 1 +Sinus bradycardia 0.8290517306700664 1.253744651478375 0.2099348326713515 1.0 0.7769652337525476 3 P0DP25 1 +Epiphyseal stippling 0.4790110672083976 1.2524654244753008 0.2104003195174673 1.0 0.7769652337525476 13 O75381,P56589,P40855 3 +Decreased calvarial ossification 0.6977376197568138 1.2497572830972692 0.2113882248249479 1.0 0.7788002606700358 4 O75844,O75718 2 +Abnormality of exocrine pancreas physiology 0.4317422125310273 1.2490160676794126 0.2116591970766197 1.0 0.7788002606700358 21 Q15904,Q9UHX1,Q9UKG1,P38398,P14174,P09601,P21266 7 +Small basal ganglia 0.5482543691019032 1.2473461607680028 0.2122705985549635 1.0 0.7788002606700358 8 P00846 1 +Abnormal glomerular mesangium morphology 0.4232315046398087 1.2457407064034225 0.2128596040597692 1.0 0.7788002606700358 22 Q14C86,Q9Y2Z9,Q8NFH4,P00813,Q8N1F7 5 +Perimembranous ventricular septal defect 0.607522814166865 1.2456340158075014 0.2128987882425757 1.0 0.7788002606700358 6 P0DP25 1 +Aplasia hypoplasia of the capital femoral epiphysis 0.6477534562212048 1.2456279541609898 0.2129010146557237 1.0 0.7788002606700358 5 Q7LGA3,O00443,O60568,Q8WVQ1 4 +Abnormal femoral neck morphology 0.3671193807919197 1.2427539668972036 0.2139585104119916 1.0 0.7793832233509389 39 Q96AY3,P51812,O75718,Q9Y619,O95831,O75844 6 +Allergy 0.5789496904711571 1.237468580648706 0.2159131718253188 1.0 0.781304655421149 7 P00813 1 +Hoarse voice 0.3916507779890439 1.235748908352519 0.2165519116077896 1.0 0.781304655421149 30 Q15056,Q8N0X7,Q9Y2U8,Q9Y3Z3,Q69YQ0,P43243,P06753,Q96HY6 8 +Wide cranial sutures 0.545989863093954 1.2352305324408253 0.2167447190353191 1.0 0.781304655421149 8 O75844,P98175,O75718 3 +Mediastinal lymphadenopathy 0.6053499778589271 1.235180546890772 0.2167633174482266 1.0 0.781304655421149 6 O15460 1 +Rapidly progressive 0.5223665158108237 1.2349567194669986 0.2168466122971377 1.0 0.781304655421149 10 Q14108,Q9Y2Z9 2 +Hip pain 0.6453296506754639 1.2346070704156866 0.2169767763274712 1.0 0.781304655421149 5 O75844,P02545,P22626 3 +Flaring of rib cage 0.8023021582733798 1.2330464866760988 0.2175584209592518 1.0 0.781304655421149 2 Q96L58 1 +Long toe 0.5006224349892228 1.230331643619372 0.2185729393167734 1.0 0.781304655421149 11 Q9UPP1,P23786 2 +Multiple lipomas 0.5450342291439474 1.230116990472444 0.2186532984833298 1.0 0.781304655421149 8 P31749,P25054 2 +Lymphangioma 0.8223012845134918 1.227641294150262 0.2195816530928835 1.0 0.781304655421149 3 P31749 1 +Hemangiomatosis 0.8223012845134918 1.227641294150262 0.2195816530928835 1.0 0.781304655421149 3 P31749 1 +Visceral angiomatosis 0.8223012845134918 1.227641294150262 0.2195816530928835 1.0 0.781304655421149 3 P31749 1 +Abnormal enchondral ossification 0.3867677058677707 1.2275490562281457 0.2196162957240837 1.0 0.781304655421149 31 O96028,Q8WVQ1,O00116,Q9Y619,O75381,P56589,P40855,Q96L58 8 +Impaired vibratory sensation 0.3719597093272783 1.22530000181942 0.2204622077238289 1.0 0.782610027348288 35 O00400,Q9Y619,Q9H0B6,P00846,O00165,Q6UWE0,Q9NR77,Q9Y5Y0,Q12768,P20700 10 +Abnormal oral physiology 0.3253003866001306 1.2242936872503574 0.220841457492382 1.0 0.782610027348288 63 Q6UN15,P51812,P55795,P35637,P43243,Q8N0X7,P42356,Q9NR77,O15460,Q03252,Q13501,Q13148,Q15165,Q92804,P06753,Q15233 16 +Mitochondrial respiratory chain defects 0.6029272771272727 1.2235234059607445 0.2211320692917446 1.0 0.782610027348288 6 P00846 1 +Spastic gait 0.3970067611752946 1.2184159822803262 0.2230659346739956 1.0 0.7840694492079865 28 P25054,Q9Y619,O00400,Q15043,Q8N0X7,P49902,Q12768,P20700 8 +Hyporeflexia of upper limbs 0.8198042602187621 1.2179912383308686 0.223227302299205 1.0 0.7840694492079865 3 Q9NR77,Q15067 2 +Abnormality of the intrahepatic bile duct 0.8197821304028812 1.2179057301388836 0.2232597984477635 1.0 0.7840694492079865 3 Q10713 1 +Abnormal synaptic transmission at the neuromuscular junction 0.3967497174972703 1.216160521627536 0.2239237792334987 1.0 0.7840694492079865 28 P35637,Q13501,Q13148,Q15165,Q92804,P06753,Q9H9S5 7 +Fibrous tissue neoplasm 0.4104905844024519 1.2117336566598855 0.2256143512074362 1.0 0.7888045982244997 23 Q969G3,Q13126,P31749,Q15392 4 +Angina pectoris 0.6867751527591829 1.2029809967826746 0.2289836744006737 1.0 0.7910398406975694 4 O75844 1 +Bulbar palsy 0.474401316043922 1.2007790192668562 0.229836932488634 1.0 0.7910398406975694 12 P35637,O43681,Q13501,Q13148,P06753 5 +Proximal amyotrophy 0.4667936362418309 1.1996616033238172 0.230270790959687 1.0 0.7910398406975694 14 O14979,Q16637,Q9H9S5,P35637 4 +Abnormal glial cell morphology 0.3213485538302517 1.1978475505923365 0.2309763716505872 1.0 0.7910398406975694 64 O95169,P00846,Q16134,P48735,P35637,Q13501,Q13148,O95831,Q6Y7W6,Q9H9P8,P37198,Q10713,P20700 13 +Alkalosis 0.6366449793419537 1.1951189288797908 0.2320405673736649 1.0 0.7916877880254378 5 Q9Y619 1 +Perseveration 0.5382155608910176 1.1936220852440114 0.2326258308661621 1.0 0.7931044409062722 8 P35637,Q13501,Q13148 3 +Abnormal vascular physiology 0.3377659452861845 1.1878278724686837 0.2349012308778619 1.0 0.7934126678854205 53 Q15056,P02545,O75844,Q14108,O15460,O95235,Q9NWM8,Q9Y3Z3,Q69YQ0,O96000,P31749,P05067,Q9NZ08 13 +Aplasia of the phalanges of the hand 0.811800179471705 1.1870832756336944 0.2351947744829319 1.0 0.7934126678854205 3 Q9BXW9 1 +Impaired antigen specific response 0.5136257338474371 1.185452015666374 0.2358387760827147 1.0 0.7934126678854205 10 O95394,P00813,Q13546 3 +Cerebral hemorrhage 0.464596673509128 1.185436487032291 0.2358449125872779 1.0 0.7934126678854205 14 P31749,P05067,P23786 3 +Lacticaciduria 0.5683067580809489 1.183941536416029 0.2364362064422422 1.0 0.7934126678854205 7 P00846 1 +Osteoarthritis 0.4679886987483499 1.182435073312595 0.2370331134106753 1.0 0.7934126678854205 13 Q14108,O75844,Q8WVQ1,P02545 4 +Toxemia of pregnancy 0.5943652508709558 1.182318194418098 0.2370794688994135 1.0 0.7934126678854205 6 O43772,P49366 2 +Abnormal sensory nerve conduction velocity 0.5360455650262779 1.182005835821328 0.2372033852827746 1.0 0.7934126678854205 8 Q9Y5Y0 1 +Adult onset 0.3115408774686397 1.181310406126892 0.2374794348988094 1.0 0.7934126678854205 68 O14979,Q12768,P20700,P02545,P41440,Q9NQZ5,O15118,Q07021,O00330,P31749,P31751,Q16637,Q06787,Q92734,P43243,Q9UGP8,P18031,P36551,Q86U42,Q8IV08,Q969G3,O95453,Q14566,O75190 24 +Abnormality of the thoracic cavity 0.4550108310418498 1.1806359311016077 0.2377473833163974 1.0 0.7937392954815158 16 Q969G3,P31749,O15460 3 +Abnormal circulating porphyrin concentration 0.6808494994236678 1.1777103803531674 0.2389120871959038 1.0 0.7953504458827235 4 P22830 1 +Increased ldl cholesterol concentration 0.5235059765226413 1.1755717483718202 0.2397660505363628 1.0 0.7963209269072843 9 Q9UJS0,P34913,P02545 3 +Hyperlipoproteinemia 0.5235059765226413 1.1755717483718202 0.2397660505363628 1.0 0.7963209269072843 9 Q9UJS0,P34913,P02545 3 +Ascending tubular aorta aneurysm 0.6322788238186988 1.1752703891744785 0.2398865570979276 1.0 0.7963209269072843 5 O75844,Q96L58,P02545 3 +Pulmonary insufficiency 0.5922276316237112 1.1720302399945346 0.2411849154416723 1.0 0.7983809080640488 6 O95235,P00813 2 +Large intestinal polyposis 0.5112534581964099 1.172013014811759 0.241191830931013 1.0 0.7983809080640488 10 P31749 1 +Extrapyramidal muscular rigidity 0.5921236546766515 1.1715298251283297 0.2413858766539487 1.0 0.798456545187246 6 Q9Y3Z3 1 +Vasculitis 0.4905075428594729 1.1702759602105153 0.2418899329064645 1.0 0.7992595223249024 11 O15460,Q9Y3Z3,Q9NZ08 3 +Ectrodactyly 0.4478843250442884 1.169480551894139 0.2422100723552707 1.0 0.7994817957997045 17 O96028,Q99720,Q9NR77 3 +Bilateral cryptorchidism 0.5096403520920485 1.1628745347086549 0.2448804107369691 1.0 0.8034239201254534 10 P37268,Q15233,P48449 3 +Sensorimotor neuropathy 0.371305623004223 1.1617736418087643 0.2453274233801319 1.0 0.8034239201254534 33 O95831,Q9NR77,P00846,Q9Y2R0 4 +Ankle flexion contracture 0.4609321827581977 1.161707635309418 0.245354243201137 1.0 0.8034239201254534 14 Q96AY3 1 +Unilateral primary pulmonary dysgenesis 0.78503597122302 1.161419107611454 0.2454715021824123 1.0 0.8034239201254534 2 Q8WYQ5 1 +Right aortic arch with mirror image branching 0.78503597122302 1.161419107611454 0.2454715021824123 1.0 0.8034239201254534 2 Q8WYQ5 1 +Double aortic arch 0.78503597122302 1.161419107611454 0.2454715021824123 1.0 0.8034239201254534 2 Q8WYQ5 1 +Abnormal labia morphology 0.4406760413476518 1.1604927361702728 0.2458482494602534 1.0 0.8035292470095459 18 P31939 1 +Abnormal patella morphology 0.375010657578173 1.1562920508586598 0.247561718701688 1.0 0.8066890227728224 32 Q96AY3,Q15056,Q04721,Q9Y619,Q8WVQ1,P21964,Q96PU5 7 +Arthritis 0.350084797595297 1.151229137301882 0.2496379811264291 1.0 0.8073089887615029 43 Q8WVQ1,P02545,P28070,Q14108,P10321,Q9Y2U8,P21964,O15460,Q9Y3Z3,P14174,O75844,Q9NZ08 12 +Abnormal vertebral morphology 0.2936605366882623 1.150315506635179 0.250013946329976 1.0 0.8075242698635788 120 Q96AY3,Q9UHX1,O75718,Q32P28,O15228,O94761,Q96L73,O95831,Q12768,Q10713,Q9Y2W2,P25054,Q9Y619,P16278,Q8NCH0,P00813,P31749,Q96HY6,Q9H9S5,P54802,O75845,Q15056,Q04721,P51812,Q8WVQ1,Q14108,P48735,O96028,P57740,Q15427,Q96L58,P61978 32 +Severe muscular hypotonia 0.3741075092659342 1.1477722101577768 0.2510626123556825 1.0 0.8091349796730556 32 P02545,Q9NWS8,O75381,P56589,Q96JM3,Q9NWM8,P40855,O95831,P06753,Q9H9S5,Q01105 11 +B lymphocytopenia 0.5295854075134785 1.1474236492386445 0.2512065717338303 1.0 0.8091349796730556 8 P00813,Q13432 2 +Abnormal shape of the palpebral fissure 0.4621893747503231 1.1455773848200828 0.2519700591308762 1.0 0.8110340619643939 13 P55795,Q9UHX1,Q9BXW9 3 +Abnormality of extrapyramidal motor function 0.3107796886098933 1.143875913978829 0.2526751012120125 1.0 0.8121824066525337 79 Q9NYB0,Q13501,Q13148,P61457,P06753,P98175,Q00577,Q9H9P8,P35610,P16278,Q9Y3Z3,Q9H0B6,Q15056,Q15043,P35637,P06865,Q6Y7W6,Q99720,O75787,Q6DKK2,P05067 21 +Abnormality of upper limb epiphysis morphology 0.4537265935562052 1.1417021646342191 0.2535778407559026 1.0 0.8127724092584909 15 O96028,P51812 2 +Rimmed vacuoles 0.4489463089244668 1.1397798843651386 0.2543780162344 1.0 0.8128759911959057 16 Q86U42,P02545,P09651,Q13501,P43243,O14979,O75190,P22626 8 +Abnormality of epiphysis morphology 0.3170152360014424 1.1395844529430788 0.2544594655115828 1.0 0.8128759911959057 64 O96028,Q8WVQ1,O00116,Q9Y619,P51812,O15228,O75381,P56589,Q9Y2U8,P40855,O95831,Q15051 12 +Unusual infection by anatomical site 0.4531035852799861 1.137589190899894 0.255292062228561 1.0 0.8132434450285726 15 O15460,Q9H9P8,Q9NZ08 3 +Malrotation of small bowel 0.6713469041612554 1.137220014128187 0.2554463222484688 1.0 0.8132434450285726 4 O96028 1 +Aplasia hypoplasia of the radius 0.4307400212959956 1.1346433270380525 0.2565247916852085 1.0 0.8143546936099204 19 Q96AY3,P25054,P38398,Q9BXW9,Q15427,P98175 6 +Pruritus 0.3961981495386061 1.1343007942200347 0.2566683961420632 1.0 0.8143546936099204 25 P22830,P00813 2 +Abnormal circulating sulfur amino acid concentration 0.5267914372585252 1.132469015392765 0.2574373037575579 1.0 0.8151307431943313 8 P55263,P41440 2 +Adducted thumb 0.387091980201292 1.1313764799146178 0.2578966666480262 1.0 0.8154780022009454 28 Q15056,P42892,Q86XL3,Q8NCH0,Q96L58 5 +Right ventricular hypertrophy 0.7954009693652762 1.1239070435369456 0.2610524629321191 1.0 0.8175972490276361 3 O95630 1 +Abnormal pyramidal sign 0.2820845341808422 1.123129809481504 0.2613823674791726 1.0 0.8175972490276361 130 P00846,Q9NR77,Q9P0J0,Q13501,Q13148,O95831,P20700,Q9Y619,O00400,P41440,Q15067,P49902,O43681,Q9Y3Z3,P37198,P51812,Q15043,P35637,Q8IY17,Q99720,Q6DKK2,Q9NZ08 22 +Increased sensitivity to ionizing radiation 0.5820136267072705 1.1228820382095694 0.2614875969629977 1.0 0.8175972490276361 6 Q969G3,P31749 2 +Hyperextensibility of the knee 0.7752517985611493 1.1209923066568457 0.2622911371820746 1.0 0.8175972490276361 2 Q8WVQ1 1 +Genu recurvatum 0.7752517985611493 1.1209923066568457 0.2622911371820746 1.0 0.8175972490276361 2 Q8WVQ1 1 +Gastrostomy tube feeding in infancy 0.3586033864905766 1.1205916348191725 0.2624617273601521 1.0 0.8175972490276361 37 P37268,P35637,Q01105 3 +Zonular cataract 0.4615035185034561 1.1202706620402294 0.2625984401072381 1.0 0.8175972490276361 12 P08670,O94761,Q9H444,Q99797 4 +Abnormal aortic valve morphology 0.3494343164503647 1.1202698797273518 0.2625987733798025 1.0 0.8175972490276361 42 P37268,Q9UHX1,P02545,P51812,Q9BXW9,P22681,P21964,O75844,Q96L58,P61978 10 +Abnormal middle phalanx morphology of the hand 0.4809857028267981 1.1137387686627382 0.2653912722126164 1.0 0.8235428433796692 11 Q03164,Q9UHX1,P02545,Q15233 4 +Sensory axonal neuropathy 0.4490573670630619 1.1108806827210935 0.2666197114055781 1.0 0.8248528991123345 15 O95831,P22626 2 +Thickened nuchal skin fold 0.4529269368116292 1.109878394666962 0.2670514317452026 1.0 0.8248528991123345 14 O75381,P56589,Q13501,P40855,P61978 5 +Peripheral demyelination 0.4264666744160417 1.103672680011777 0.2697351508263961 1.0 0.829280934718073 19 O43681,Q9Y5Y0,P00846,P20700 4 +Global brain atrophy 0.4051375557492301 1.1031985446524488 0.2699409532136578 1.0 0.829280934718073 22 Q9UHX1,O95169,P35637,Q13501,Q13148 5 +Papillary renal cell carcinoma 0.61633211843271 1.10283938993747 0.2700969189717908 1.0 0.829280934718073 5 Q92733 1 +Fibrosarcoma 0.7892137462957268 1.1001371097549335 0.2712723870804803 1.0 0.8301023741240192 3 Q13126 1 +Flat forehead 0.6154486891640882 1.0988311495954757 0.2718417225228617 1.0 0.8305226270404098 5 Q8NCH0 1 +Upper limb muscle weakness 0.383273517292346 1.097849094654232 0.27227038952504 1.0 0.8305226270404098 28 P36551,P02545,Q969G3,P00846,Q8N0X7,Q92734,P46976,P31749,P37198,Q8NCE2 10 +Abnormal circulating fatty acid concentration 0.4187129801115796 1.095301110581036 0.2733847411252312 1.0 0.8308649400422076 20 O75381,P56589,P23786,O43772 4 +Butterfly vertebrae 0.787450316879659 1.093370133299132 0.2742313213494456 1.0 0.8308895803778324 3 O75845 1 +Upper airway obstruction 0.6133067008695685 1.089115160315829 0.2761031052745979 1.0 0.8308895803778324 5 O75844,P02545 2 +Pulmonary embolism 0.6598409357102583 1.088276320310659 0.2764731409557464 1.0 0.8308895803778324 4 Q9NZ08 1 +Cyanosis 0.4360227790598684 1.0876978405829312 0.2767285213586108 1.0 0.8308895803778324 17 O43772,O75844,P98175,P51812 4 +Motor axonal neuropathy 0.4355409004732656 1.0843771652084475 0.2781976040539837 1.0 0.8308895803778324 17 O95831,Q8IY17 2 +Hip contracture 0.4556783755725409 1.0839294125014498 0.2783960973961132 1.0 0.8308895803778324 12 Q96L73,Q96AY3,Q7LGA3,P06753 4 +Lymphoma 0.3816572204212131 1.0836598334814176 0.2785156509968587 1.0 0.8308895803778324 28 P25054,Q08J23,O95394,O95453,Q01130,P00813 6 +Optic nerve hypoplasia 0.4236541642524847 1.0832959293872717 0.27867709152755 1.0 0.8308895803778324 19 P37268,O75312,Q9UHX1,P61978,Q9H9S5,Q15058,Q9NVI7 7 +Hallux valgus 0.4236113316223657 1.0829856607146289 0.2788147877903446 1.0 0.8308895803778324 19 Q15056,Q96L58,P57740,P31749,Q15233 5 +Hypothermia 0.4953707446699577 1.082061554349637 0.2792251774721259 1.0 0.8308895803778324 10 O43772,P00846 2 +Retinopathy 0.3583489130780822 1.078823062182392 0.2806666119324275 1.0 0.8308895803778324 34 O96028,P07437,Q9Y375,O95169,P00846,Q9UKG1,Q9NZ08 7 +Insidious onset 0.572648067985209 1.077851823514992 0.281099887988169 1.0 0.8308895803778324 6 O60313,Q9NR77,Q12768 3 +Heterochromia iridis 0.7830997435363575 1.0766910682340316 0.2816183039570945 1.0 0.8308895803778324 3 Q8IY17 1 +Abnormal circulating ferritin concentration 0.5469631653581328 1.076622643332257 0.2816488840877857 1.0 0.8308895803778324 7 P41440 1 +Blue sclerae 0.4017174022489226 1.0762597503397069 0.2818111041508739 1.0 0.8308895803778324 22 Q96AY3,O75718,Q8NCH0 3 +Abnormal morphology of the musculature of the neck 0.4509321499706489 1.0740670420562068 0.282792634792343 1.0 0.8308895803778324 13 P35637 1 +Transient neonatal diabetes mellitus 0.7634532374100701 1.0724396094770146 0.2835226251028016 1.0 0.8308895803778324 2 Q9UKG1 1 +Abnormal oral glucose tolerance 0.7634532374100701 1.0724396094770146 0.2835226251028016 1.0 0.8308895803778324 2 Q9UKG1 1 +Hypoinsulinemia 0.7634532374100701 1.0724396094770146 0.2835226251028016 1.0 0.8308895803778324 2 Q9UKG1 1 +Widely spaced incisors 0.6559170745752944 1.0716123982533985 0.2838941622482815 1.0 0.8308895803778324 4 Q8WVM7,Q8WXI9,Q9BSJ2 3 +Polar cataract 0.7812320092112748 1.0695378533245492 0.2848273815476618 1.0 0.8310230019091379 3 P25054,P08670 2 +Abnormal sweat gland morphology 0.7811464405125386 1.069210242681937 0.2849749443787832 1.0 0.8310230019091379 3 O75844 1 +Hypoketotic hypoglycemia 0.5146578851622924 1.0675659412487095 0.2857163538149383 1.0 0.8310230019091379 8 O43772,P23786 2 +Abnormal hdl cholesterol concentration 0.654781797586346 1.066794102164129 0.2860648224199433 1.0 0.8310230019091379 4 Q9UJS0 1 +Abnormality of chromosome stability 0.4322562084214814 1.0617486039787718 0.2883498279142755 1.0 0.8327066345438934 17 P33991,Q969G3,Q9BXW9,P13073,P31749 5 +Severe short stature 0.3898324102264068 1.06133912870296 0.2885358094657366 1.0 0.8327066345438934 24 Q8IY17,Q8WVQ1,Q9Y619,Q15392,Q96L58,P53701,Q96HY6 7 +Overtubulated long bones 0.778791326528413 1.0601971940920047 0.2890548973684741 1.0 0.8327066345438934 3 O75844 1 +Aplasia of metacarpal bones 0.7783589151799444 1.0585431616212566 0.2898078840809026 1.0 0.8333316716111775 3 Q9BXW9 1 +Dolichocephaly 0.3455442412542353 1.057032864825041 0.2904965886400614 1.0 0.8337699011798441 41 O96028,Q4J6C6,Q04721,O75381,Q03164,P56589,P38398,Q9BXW9,P42356,P40855,O95721,P31749,P61978 13 +Joint contracture of the hand 0.3303239037270922 1.0559393783295028 0.2909959118896958 1.0 0.8342302317349786 49 Q8WVQ1,P02545,Q9Y619,Q99567,O75844,P42892,Q15392,Q9NR77,O95155,P57740,Q96L73,Q9Y5Y0,P06753 13 +Bladder diverticulum 0.5119886344318195 1.053302382693139 0.2922024272432058 1.0 0.8367632795739193 8 Q9NWM8 1 +Dystrophic toenail 0.5668833841900466 1.050164254275494 0.2936426010150255 1.0 0.8386706008169497 6 Q969G3,O75844 2 +Secondary growth hormone deficiency 0.566732100535482 1.0494380290762928 0.2939765631404214 1.0 0.8388887537620248 6 P31749 1 +Arteriovenous malformation 0.5112039827081352 1.049110808107094 0.2941271222760111 1.0 0.8388887537620248 8 P31749,Q9BXW9 2 +Aortic valve calcification 0.7755551949481188 1.0478248434122373 0.2947193141621378 1.0 0.8395794010207116 3 O75844 1 +Advanced eruption of teeth 0.4467216687261319 1.0473490797129563 0.2949386075991833 1.0 0.8395794010207116 13 O75844,Q69YQ0,P51812,P02545 4 +Nasogastric tube feeding in infancy 0.4995749303671898 1.043939492486482 0.2965133850198362 1.0 0.8406644831489795 9 Q9UHX1,P61978 2 +Abnormal heart valve morphology 0.3039851776457067 1.043294753067143 0.2968118004371403 1.0 0.8406644831489795 82 P37268,Q9UHX1,P38398,P06753,Q12768,P02545,Q9BXW9,P16278,P21964,P22681,O95155,Q8NCH0,Q15056,P51812,P53701,Q9UER7,Q15233,O96028,P55795,O75844,Q96PU5,Q96L58,P61978 23 +Abnormality of limb epiphysis morphology 0.3630191313696045 1.0431816905066964 0.2968641517466486 1.0 0.8406644831489795 32 O96028,Q8WVQ1,P51812,O15228,O95831 5 +Abnormal circulating follicle stimulating hormone concentration 0.4987635830238037 1.0394839549339676 0.2985797164448587 1.0 0.8427322787281284 9 P31749 1 +Increased circulating lactate dehydrogenase concentration 0.4380202766036848 1.0380949343117154 0.2992258596041628 1.0 0.842747227774043 15 P23786,Q9UJS0,P41440 3 +Poor gross motor coordination 0.6010116232900522 1.0334282620883235 0.3014035261265499 1.0 0.8454813175923325 5 Q9H9S5,O75503 2 +Gliosis 0.3346776675737066 1.0332956278326717 0.3014655727178492 1.0 0.8454813175923325 45 O95169,P00846,Q16134,P35637,Q13501,Q13148,Q6Y7W6,P37198,Q10713,P20700 10 +Recurrent viral infections 0.441021512284243 1.0328860420215074 0.3016572315247152 1.0 0.8455104133601393 14 P33991,P00813,Q13432 3 +Cutaneous cyst 0.6459209863196809 1.0292398614856926 0.3033669752110137 1.0 0.8458093502531988 4 Q9H488,P25054 2 +Peripheral cyanosis 0.5373427739620789 1.0283362678290426 0.3037916764577288 1.0 0.8458093502531988 7 P51812 1 +Tetraplegia 0.4398339821321236 1.0252165013261705 0.3052610438423984 1.0 0.8458093502531988 14 O95831,Q13423 2 +Shuffling gait 0.4657436468360926 1.0233576749139457 0.3061387634958912 1.0 0.8458093502531988 11 O75844,Q6Y7W6 2 +Pulmonary artery atresia 0.7691387276064703 1.0233386310843862 0.3061477644543555 1.0 0.8458093502531988 3 Q8WYQ5 1 +Hyperconvex fingernails 0.5611241653612319 1.0225338486068898 0.3065283006882513 1.0 0.8458093502531988 6 P51812 1 +Abnormal circulating aromatic amino acid concentration 0.6443215979647396 1.0224721385575777 0.3065574928211836 1.0 0.8458093502531988 4 Q9UJS0 1 +Fibroadenoma of the breast 0.5984617549879839 1.0219007072602224 0.3068278976948129 1.0 0.8458093502531988 5 P31749 1 +Coronary artery atherosclerosis 0.5980682611998995 1.020122538023363 0.3076703490159946 1.0 0.8458377078247741 5 P34913 1 +Decreased circulating acth level 0.5354805438210131 1.0190004224602651 0.3082027659652731 1.0 0.8458377078247741 7 P31749 1 +Abnormality of the larynx 0.3255921104550136 1.018803007367452 0.3082964977057081 1.0 0.8458377078247741 51 P25054,Q9UHX1,P02545,P35637,P43243,P21964,Q15427,Q13501,Q13148,Q15165,Q92804,Q69YQ0,Q96HY6 13 +Tapered finger 0.3470507057095088 1.018520336820613 0.3084307411527294 1.0 0.8458377078247741 38 Q06136,P42892,P51812,P23786 4 +Intestinal polyp 0.414599468230438 1.017760499906515 0.3087917879260855 1.0 0.8458377078247741 19 P42892,P31749 2 +Talipes calcaneovalgus 0.6431906194087489 1.0176886537949192 0.3088259410303551 1.0 0.8458377078247741 4 Q9NR77 1 +Protruding tongue 0.4386444373097807 1.0175363944177898 0.308898328015339 1.0 0.8458377078247741 14 Q10713,P20700 2 +Aplasia hypoplasia involving the vertebral column 0.4347457219820236 1.0165320021171445 0.3093761161160278 1.0 0.8461938578410939 15 P16278,O95831,Q04721,Q96HY6 4 +Single transverse palmar crease 0.3306633786679614 1.015739280840546 0.3097535572074945 1.0 0.8461938578410939 46 O96028,Q8IY17,Q9UHX1,P51812,O75381,P56589,P40855 7 +Abnormality of retinal pigmentation 0.3017920709014711 1.0109969533361225 0.3120178879833704 1.0 0.8475547056228535 82 Q8IY17,P51812,Q8N183,P00846,O75381,Q15067,P31749,Q13432,P56589,Q9Y5Y0,P53701,Q15051 12 +Eruption failure 0.5036396955471687 1.008739903663699 0.3130993891400027 1.0 0.848357092466069 8 O75844,P25054 2 +Ovarian cyst 0.4133328413871597 1.0086042762287013 0.3131644556926449 1.0 0.848357092466069 19 P31751,Q03252,P31749,P02545 4 +Spinal cord lesion 0.4931120499505584 1.0084715625804517 0.3132281329878852 1.0 0.848357092466069 9 Q9Y2U8,Q04721,O00400 3 +Synostosis of metacarpals metatarsals 0.6409591225524938 1.008256028069733 0.3133315666968899 1.0 0.848357092466069 4 Q15233 1 +Craniofacial hyperostosis 0.502975280672799 1.0051975587624309 0.3148017304610306 1.0 0.8511508816639113 8 P31749,P51812 2 +Maturity onset diabetes of the young 0.7636729994242896 1.0025318354191206 0.3160867988382634 1.0 0.8532667138442915 3 P61457,Q9UKG1 2 +Impaired proprioception 0.3341281574079017 1.0015150072132877 0.3165778884591446 1.0 0.8532667138442915 44 Q06787,Q15120,O00400,P41440,Q9Y619,Q9H0B6,P00846,Q13217,O00165,Q6UWE0,Q8N0X7,Q9NR77,P54802,Q9Y5Y0,Q12768,P20700 16 +Arteriosclerosis 0.418123462833003 1.0012996453086762 0.3166819643362926 1.0 0.8532667138442915 18 O75845,P02545,P34913,O15118,O75844,Q14191 6 +Abnormality of the alveolar ridges 0.530795687658302 0.9955335436423648 0.3194768383388466 1.0 0.8566422360381615 7 Q15392 1 +Increased adipose tissue 0.6376583126968771 0.9943174366385864 0.3200683493722169 1.0 0.8566422360381615 4 P31751,P02545 2 +Gastrointestinal obstruction 0.4313236971543691 0.9940197135130628 0.3202132701184244 1.0 0.8566422360381615 15 P25054,P42892,Q01844 3 +Abnormal sclera morphology 0.3683200164612284 0.9937668222278258 0.3203364020539592 1.0 0.8566422360381615 29 Q96AY3,P31749,O75718,Q8NCH0 4 +Exostoses 0.5919027385206742 0.9922895850738755 0.3210562823723495 1.0 0.8566422360381615 5 P31749 1 +Amyloidosis 0.7608144069000837 0.9916700290583844 0.3213585158416183 1.0 0.8566422360381615 3 P05067 1 +Retinal thinning 0.7427338129496381 0.98783136843132 0.3232352421295035 1.0 0.8566422360381615 2 P04439 1 +Wide anterior fontanel 0.3808087331085141 0.987096297036512 0.3235954329206985 1.0 0.8566422360381615 24 O75718,O75381,Q16134,P56589,P40855 5 +Duodenal adenocarcinoma 0.7424460431654656 0.9866631309930576 0.3238078101312935 1.0 0.8566422360381615 2 P25054 1 +Adenocarcinoma of the small intestine 0.7424460431654656 0.9866631309930576 0.3238078101312935 1.0 0.8566422360381615 2 P25054 1 +Abnormal visual electrophysiology 0.3207858627432099 0.9832486898205663 0.3254850565305827 1.0 0.8566422360381615 53 Q8IY17,P00846,Q15067,O43681,Q9Y5Y0,P50897,Q15051,P37198 8 +Abnormal proportion of cd4 positive t cells 0.488466143237521 0.9830130884896524 0.3256009969664672 1.0 0.8566422360381615 9 O95394,Q13432,O75787 3 +Achilles tendon contracture 0.4394258832541182 0.9827499740815612 0.3257305084488591 1.0 0.8566422360381615 12 O60313,P02545,Q08J23,Q8TD16,Q9H9S5 5 +Abnormal protein o linked glycosylation 0.7583587570132609 0.982350961513738 0.3259269763079451 1.0 0.8566422360381615 3 Q8N511 1 +Aplasia hypoplasia of the optic nerve 0.3777253668810471 0.9798970346087456 0.327136946891214 1.0 0.8566422360381615 25 P37268,P25054,Q9UHX1,O95721,P61978 5 +Sclerocornea 0.4326044162424716 0.9785834501345648 0.3277858398934961 1.0 0.8566422360381615 14 P53701 1 +Impotence 0.4385895609055112 0.9775564591194332 0.3282937409655753 1.0 0.8566422360381615 12 P31749,P20700 2 +Erectile dysfunction 0.4385895609055112 0.9775564591194332 0.3282937409655753 1.0 0.8566422360381615 12 P31749,P20700 2 +Hemivertebrae 0.4383469881920957 0.9760504001167636 0.329039488978573 1.0 0.8566422360381615 12 Q9UHX1,Q9Y619 2 +Abnormal placenta morphology 0.4871509078204695 0.9758126807379256 0.3291572995913847 1.0 0.8566422360381615 9 O75844,P02545 2 +Anal stenosis 0.633170169881964 0.9753938316274576 0.3293649422317841 1.0 0.8566422360381615 4 Q69YQ0,O75419,Q08J23 3 +Pituitary hypothyroidism 0.497314094024035 0.9750434795166756 0.3295386929492256 1.0 0.8566422360381615 8 P31749 1 +Dysplastic corpus callosum 0.457439593182083 0.9742505911958764 0.3299321305989222 1.0 0.8566422360381615 11 P49902 1 +Headache 0.2987890464969146 0.9722310618466524 0.3309356109152177 1.0 0.8566422360381615 77 Q8N1F7,Q8NFH4,P25054,Q969G3,P00846,Q9NQZ5,P23786,O15460,Q9Y3Z3,Q01130,P06753,P31749,P05067,Q9NZ08 14 +Irritability 0.298628279207689 0.9699064484773215 0.3320931254955979 1.0 0.8566422360381615 77 P37268,O43772,Q9UJS0,Q8N1F7,P61457,P00846,Q15067,Q9Y3Z3,Q13501,O95831,P50897,Q9NZ08 12 +Temporal optic disc pallor 0.7375539568345302 0.9668354556671496 0.3336262968529491 1.0 0.8566422360381615 2 O60313 1 +Morning glory anomaly 0.7375539568345302 0.9668354556671496 0.3336262968529491 1.0 0.8566422360381615 2 O60313 1 +Impacted tooth 0.6310257787706102 0.9663648369680083 0.3338616527762317 1.0 0.8566422360381615 4 O75844 1 +Pelvic kidney 0.485081805460283 0.9644917913793156 0.3347994218836794 1.0 0.858426172561915 9 Q9UHX1,Q9BXW9 2 +Heteronymous hemianopia 0.5238715323449468 0.9609096695672376 0.3365975884468239 1.0 0.858426172561915 7 P31749 1 +Subependymal cysts 0.7358273381294942 0.9598524924262376 0.3371294590824507 1.0 0.858426172561915 2 O00330 1 +Abnormal form of the vertebral bodies 0.2970014133538368 0.9571736002532496 0.3384796396453899 1.0 0.8599766264012664 93 Q96AY3,Q9UHX1,Q32P28,O15228,O95831,Q10713,Q12768,Q9Y2W2,P25054,Q9Y619,P16278,P00813,P31749,Q96HY6,P54802,O75845,Q15056,Q04721,P51812,Q8WVQ1,P48735,O96028,Q15427,Q96L58 24 +Cachexia 0.3930697747781709 0.9533884771313628 0.3403932775239484 1.0 0.8617243761628719 21 Q99720,P31749,Q01844,P35637 4 +Aplasia hypoplasia of the palmar creases 0.7505812407626118 0.9529114131991352 0.3406349568501841 1.0 0.8617243761628719 3 Q8NCH0 1 +Cranial asymmetry 0.5463641299534729 0.9519159473666856 0.3411396110971119 1.0 0.8619041961846857 6 O96028,P40855 2 +Mild short stature 0.6271235243305673 0.9499565306737184 0.3421343406250661 1.0 0.862047567347253 4 Q8WVQ1,Q13555,P10644 3 +Abnormal chromosome morphology 0.7329496402877675 0.9482323800577608 0.3430111663927739 1.0 0.862047567347253 2 O95453 1 +Delayed menarche 0.5451929897890071 0.9463276691084122 0.3439814849749161 1.0 0.8620793368742659 6 O00429,Q9UJS0,P02545,O75844 4 +Abnormality of the metacarpal bones 0.3290332033075066 0.945535488872158 0.3443855615108868 1.0 0.8621654637073409 44 O96028,P25054,Q8WVQ1,P51812,Q32P28,Q96L58,Q9BXW9,O94761,P31749,Q15233,O60828 11 +Abnormality of the brainstem white matter 0.6251139864664781 0.9415185136927364 0.34643920627654 1.0 0.8649852559281492 4 P20700 1 +Abnormality of the 1st metacarpal 0.4326841150594446 0.9409337512091992 0.3467388101209185 1.0 0.8652700965243254 12 Q8WVQ1,Q9BXW9,Q15233 3 +Urinary bladder sphincter dysfunction 0.4700344221212137 0.9390729889016758 0.347693271316547 1.0 0.8671879237542114 10 Q06787,P09651,Q9NR77,P22626,Q12768 5 +Gynecomastia 0.3835455295106346 0.9334886506785198 0.3505677275896446 1.0 0.8700719515488495 22 Q8IY17,P31749 2 +Gonadal neoplasm 0.3615084829376296 0.9331423710675386 0.3507464647409564 1.0 0.8700719515488495 29 Q13423,Q01844,P02545,P48735,P38398,P31749,Q14191 7 +Aplasia hypoplasia involving forearm bones 0.3833686693460426 0.9321038626736592 0.351282852016098 1.0 0.8700719515488495 22 Q96AY3,P25054,P38398,Q9BXW9,Q15427,P98175 6 +Ragged red muscle fibers 0.4131729535939536 0.9306764343950388 0.352020963244571 1.0 0.8700719515488495 17 O95831,P00846 2 +Abnormal femoral neck head morphology 0.3199974948108215 0.9288942297414808 0.3529439036754842 1.0 0.871891084079692 48 Q96AY3,P51812,O75718,Q9Y619,O95831,O75844 6 +Immunologic hypersensitivity 0.3544252736269654 0.928457817661741 0.3531701390645478 1.0 0.8719881040746698 31 Q08J23,O95394,P22681,Q01130,P00813,Q9NZ08 6 +Posterior pituitary dysgenesis 0.6210244951206298 0.9243729684052778 0.3552921636677786 1.0 0.8737147920047145 4 Q9UHX1 1 +Increased circulating antibody level 0.4070751360189536 0.9236571426333662 0.3556648523857115 1.0 0.8737147920047145 18 Q14108,O95394,P00813,P28070 4 +Anisopoikilocytosis 0.7427305812892011 0.9233217339261448 0.3558395649414985 1.0 0.8737147920047145 3 Q05682 1 +Abnormal connection of the cardiac segments 0.3058474570716267 0.9227457247862774 0.3561397312074406 1.0 0.8737147920047145 61 Q15056,Q04721,Q9UHX1,P02545,P57076,O75844,Q969G3,P38398,Q9BXW9,O15460,P21964,O95155,Q69YQ0,P40855,Q15427,Q8WYQ5,P98175,Q12768 18 +Undetectable electroretinogram 0.5763638800750817 0.9224291153838288 0.3563047886777373 1.0 0.8737147920047145 5 Q9Y5Y0 1 +Neoplasm of the respiratory system 0.4115155628399878 0.9193399091261264 0.3579178093705781 1.0 0.8753689894621796 17 Q01844,P02545,Q96L73,P31749,Q14191 5 +Clonus 0.3409998804001258 0.9186940675638652 0.3582556136748165 1.0 0.8754403750335983 35 Q9Y619,O00400,Q15043,Q99720,P35637,Q3ZCQ8,Q8N0X7,Q9BQT8,Q9H9S5,Q12768,P20700 11 +Sclerosis of hand bone 0.7254676258992785 0.9181318548830724 0.3585498395265221 1.0 0.8754403750335983 2 P02545 1 +Abnormal tarsal ossification 0.7254676258992783 0.9181318548830714 0.3585498395265225 1.0 0.8754403750335983 2 Q8WVQ1 1 +Lactose intolerance 0.7400409353787447 0.9132159741249776 0.3611289641841484 1.0 0.8763793208186205 3 Q14566 1 +Decreased activity of mitochondrial complex iv 0.422413558098288 0.913073722380976 0.3612037695952517 1.0 0.8763793208186205 14 Q70HW3,Q9Y2R0 2 +Constriction of peripheral visual field 0.3875369448435531 0.9113216898742984 0.3621259013586102 1.0 0.8769237818985244 21 O75381,P00846,P56589,P40855 4 +Phenotypic variability 0.2879850925489975 0.9064807626217952 0.3646814426104998 1.0 0.8789558014279302 108 O60313,Q9Y375,Q8TD16,P00846,Q9NR77,O00429,P06753,Q00577,O14979,P02545,P00374,Q13868,P49792,Q92733,Q9Y3Z3,O00330,Q9UBB4,Q15125,Q15058,Q9H9S5,Q6UWE0,Q9H061,Q06787,Q8WVQ1,Q14671,P11166,Q9NQT5,P46976,P43243,Q9BUF5,P36551,Q70HW3,Q9NWS8,Q9UEY8,Q5T160,Q969G3,Q13813,O95453,Q8WWY3,Q6P4A7,P57740,Q15427 42 +Social and occupational deterioration 0.7380643246142957 0.9058001587461076 0.3650416369915974 1.0 0.8789558014279302 3 Q9BQE5 1 +Dry skin 0.339657187085477 0.905451035852092 0.3652264886722403 1.0 0.8789558014279302 35 P37268,Q06136,P00813,Q08J23 4 +Abnormal right ventricle morphology 0.5124717115243553 0.9041021807707892 0.3659412221406981 1.0 0.8792085716820737 7 P06753,O95630 2 +Oculomotor nerve palsy 0.5116691805711575 0.9001139418264196 0.3680596173238943 1.0 0.8815743758208554 7 P31749 1 +Arrhinencephaly 0.4626961493181734 0.8978979995424926 0.3692399312755783 1.0 0.8815743758208554 10 P21964,Q9Y3Z3 2 +Abnormal atrioventricular valve morphology 0.338841959753215 0.8974152450965025 0.3694973806433235 1.0 0.8815743758208554 35 Q15056,P51812,P02545,P53701,O75844,P55795,P21964,P06753,Q96L58,Q12768 10 +Spinal cord compression 0.5349112121855243 0.8973848783049944 0.3695135787576959 1.0 0.8815743758208554 6 P31749,P25054 2 +Patellar aplasia 0.5704618884831707 0.8960260627786846 0.3702388436410948 1.0 0.8815743758208554 5 Q9Y619 1 +Breast aplasia 0.7350860872740779 0.8946444053720696 0.3709772063044663 1.0 0.8815743758208554 3 Q9Y619 1 +Fatty replacement of skeletal muscle 0.4619829242615522 0.893904185920471 0.3713731579447512 1.0 0.8815743758208554 10 P51114,P22626,Q9H9S5,P09651 4 +Increased cerebral lipofuscin 0.5699110853428982 0.8935662617576373 0.3715540044838268 1.0 0.8815743758208554 5 P50897 1 +Falls 0.46139330463314 0.8906036912344788 0.373141818252009 1.0 0.8815743758208554 10 Q5T8D3,Q9BQT8 2 +Hydrocele testis 0.4710708110209404 0.8880905629573722 0.3744920385175039 1.0 0.8815743758208554 9 O15047,P31749,Q9UBX3,Q96L73 4 +Anomalous trichromacy 0.7333179902671731 0.8880320331936398 0.3745235205699349 1.0 0.8815743758208554 3 O60313 1 +Tritanomaly 0.7333179902671731 0.8880320331936398 0.3745235205699349 1.0 0.8815743758208554 3 O60313 1 +Bilateral sensorineural hearing impairment 0.3666001829174888 0.8873456488118352 0.3748928358504995 1.0 0.8815743758208554 25 Q15067,P35637,O43681,P38159,Q13501 5 +Loss of ability to walk 0.4068237085200128 0.8873041993496283 0.3749151453102792 1.0 0.8815743758208554 17 P00846,Q9H9S5,P37198 3 +Vertebral segmentation defect 0.3494774627241558 0.8829353030763633 0.3772712280791879 1.0 0.8833685072717535 31 O96028,Q15056,Q9UHX1,Q9Y619,P61978,Q9H9S5,Q12768 7 +Abnormal b cell morphology 0.4231942771457893 0.8823041274594228 0.3776123650265721 1.0 0.8833685072717535 12 P00813,Q13432 2 +Hand polydactyly 0.332236969138217 0.8820701723020363 0.3777388610693177 1.0 0.8833685072717535 39 O75845,O96028,Q8IY17,Q9UHX1,Q9UPP1,Q12768,Q15067,Q9BXW9,P98175,Q10713 10 +Epidermal acanthosis 0.4416705012447361 0.8814487968858815 0.3780749561787138 1.0 0.8833685072717535 11 Q06136 1 +Abnormal acetabulum morphology 0.3835508088180872 0.8810942135859293 0.3782668288938704 1.0 0.8833685072717535 21 Q6NUQ1,Q96AY3,Q8WVQ1,O75718,P16278,Q96L58 6 +Narrow palpebral fissure 0.4058168662405477 0.8804413715880239 0.3786202526671336 1.0 0.8833685072717535 17 O95394,Q03164,O94761,P38159,Q8WYQ5 5 +Cortical myoclonus 0.7159712230215804 0.8801794255776234 0.3787621173780084 1.0 0.8833685072717535 2 O95394 1 +Upper limb amyotrophy 0.4136366033866493 0.8781755041375965 0.3798484832710782 1.0 0.8833685072717535 15 Q9NR77,Q9BQT8,Q13501 3 +Tetralogy of fallot 0.3159954340805829 0.8773101994847082 0.3803181737996743 1.0 0.8833685072717535 47 Q15056,Q04721,Q9UHX1,Q969G3,P38398,Q9BXW9,P21964,O95155,Q69YQ0,Q15427,Q8WYQ5,P98175,O60828,Q12768 14 +Decreased circulating level of specific antibody 0.4781973031665713 0.8737224974601883 0.3822693960609544 1.0 0.8848161107832712 8 P00813 1 +Abnormality of the umbilical cord 0.458105970266511 0.872222535094005 0.3830869880453078 1.0 0.8855326366065116 10 O75844,Q12768 2 +Abnormality of the wrist 0.3339739314315733 0.8717616490013043 0.3833384205207004 1.0 0.8855326366065116 37 Q04721,P25054,P02545,Q8WVQ1,O94761,O95831,O75844,P31749,Q96L58 9 +Non midline cleft lip 0.5056551517956166 0.8702797451532164 0.3841475452010623 1.0 0.8865235778415411 7 Q15427,Q96L58,P35453,O60716 4 +Scotoma 0.415427960842319 0.8683726004087037 0.385190389453574 1.0 0.8865778297060648 14 Q9H061,P00846,Q9Y5Y0 3 +Small placenta 0.7278977599441301 0.8678120492419288 0.3854972327026915 1.0 0.8865778297060648 3 O75844 1 +Short umbilical cord 0.7278977599441301 0.8678120492419288 0.3854972327026915 1.0 0.8865778297060648 3 O75844 1 +Abnormal speech prosody 0.4672056157048472 0.867109784839436 0.3858818598420479 1.0 0.8865778297060648 9 P00846 1 +Abnormal nephron morphology 0.2898176491801986 0.8662411172398797 0.3863579494144111 1.0 0.8872346017079338 70 Q8N1F7,Q15056,Q9NZ08,Q9NQH7,P02545,Q14108,Q86YH6,P00846,O95394,O95169,Q14C86,P23786,P57740,Q03252,Q8NFH4,P00813,Q9Y2Z9 17 +Thick corpus callosum 0.7122302158273358 0.8653124168898758 0.386867337446847 1.0 0.8874629007590836 2 Q15233 1 +Cognitive impairment 0.2710123905430067 0.8609666418748683 0.3892564157284208 1.0 0.8874629007590836 175 P00846,Q13501,Q9Y2R0,O95831,Q13148,P22626,P20700,Q10713,Q9BQE5,Q9Y619,Q9NQZ5,P27544,O43681,P31749,Q9UJS0,Q14108,O75381,P35637,O75503,Q6Y7W6,Q8IY17,O95169,Q99720,Q969G3,P56589,Q6DKK2,P40855,P05067,P50897,Q9NZ08 30 +Impaired oropharyngeal swallow response 0.7110791366906452 0.8607480318604741 0.3893768326846967 1.0 0.8874629007590836 2 Q9NR77 1 +Contractures of the large joints 0.711079136690645 0.8607480318604741 0.3893768326846967 1.0 0.8874629007590836 2 O75431 1 +Transient global amnesia 0.5270022181154103 0.8599050793740175 0.389841368352338 1.0 0.8874629007590836 6 P31749 1 +Respiratory arrest 0.4755331034996471 0.8596814349366381 0.3899646712464322 1.0 0.8874629007590836 8 P23786 1 +Bulbous nose 0.3211768493489056 0.8594893692489171 0.3900705826100763 1.0 0.8874629007590836 44 Q02252,P42892,P38159 3 +Erythema 0.363185924522267 0.8590603427340957 0.3903072251493424 1.0 0.8875455338007203 25 P22830,Q06136,P53701,O95394 4 +Abnormality of the tongue 0.2887756287989155 0.8556211095057127 0.3922073897308158 1.0 0.889283065485914 99 P51114,Q16637,O75381,P98175,P56589,O15460,Q9BQT8,P40855,O95831,O75844,P31749,P61978,P20700 13 +Short chin 0.413255022620287 0.8545092730944324 0.3928228736043277 1.0 0.8902458126776408 14 O75844,P02545,Q08J23 3 +Prominent eyelashes 0.4646568844859459 0.8533019275946796 0.3934918914069569 1.0 0.8903766750590012 9 P20700 1 +Cerebral palsy 0.4182777167294677 0.8520617201191345 0.3941798367882223 1.0 0.8903766750590012 12 P98175,P48735 2 +Abnormal metacarpal morphology 0.3351153537109537 0.8515787547150663 0.3944479353846981 1.0 0.8903766750590012 34 Q8WVQ1,P51812,Q32P28,Q96L58,Q9BXW9,O94761,Q15233,O60828 8 +Atrophy degeneration involving the spinal cord 0.5015354628263063 0.8499015558630238 0.3953798204996928 1.0 0.8903766750590012 7 Q8IY17 1 +Adrenal insufficiency 0.3424273512238356 0.8497588040263871 0.3954591976616666 1.0 0.8903766750590012 32 Q13423,Q969G3,O75381,P04150,P56589,P40855,P31749 7 +Oligomenorrhea 0.5011569637158138 0.8480318758929938 0.39642021882148 1.0 0.8903766750590012 7 P31751 1 +Reduced natural killer cell count 0.5596309956413141 0.8478051100719772 0.3965465167491082 1.0 0.8903766750590012 5 P33991,O95394 2 +Abnormal natural killer cell morphology 0.5596309956413141 0.8478051100719772 0.3965465167491082 1.0 0.8903766750590012 5 P33991,O95394 2 +Demyelinating peripheral neuropathy 0.3852048133049622 0.8472219027801382 0.3968714473927397 1.0 0.8903766750590012 20 Q9NR77,P00846,P41440 3 +Hypertriglyceridemia 0.361708495601815 0.8468420811450609 0.3970831492199225 1.0 0.8903766750590012 25 P31751,P22830,P28070 3 +Aortic arch aneurysm 0.4729434301734552 0.8460557820158338 0.39752162651626 1.0 0.8903766750590012 8 O95155 1 +Nail dysplasia 0.3419383262937913 0.8451917805463206 0.3980037707543273 1.0 0.8903766750590012 32 O96028,P42892,P51812,Q9Y619 4 +Preaxial hand polydactyly 0.4085629558908328 0.8451617511382968 0.3980205345900995 1.0 0.8903766750590012 15 O96028,Q9UPP1,Q9UHX1 3 +Limitation of movement at ankles 0.6018678619710576 0.8445963474974995 0.3983362490585076 1.0 0.8903886488907784 4 O75844 1 +Diffuse white matter abnormalities 0.4529245265544602 0.8433258667717564 0.399046220030629 1.0 0.8905031436472985 10 O95169,Q9H9S5,Q3ZCQ8 3 +Abnormality of femur morphology 0.2880684829935585 0.8416165998708226 0.4000025945253314 1.0 0.8917839870297063 70 Q6NUQ1,Q96AY3,Q9UHX1,O75718,P02545,Q32P28,O00116,Q9Y619,Q8WVQ1,P51812,P38398,Q9BXW9,Q96L58,P16278,O95831,O75844,Q96HY6 17 +Meningioma 0.43405973655009 0.8369536744132385 0.4026186081469034 1.0 0.8946227672211327 11 Q969G3,P31749,P02545 3 +Unusual fungal infection 0.4614356006491931 0.8358836187892437 0.4032203788422335 1.0 0.895383468128977 9 P00813 1 +Overriding aorta 0.4510446220306754 0.8328665716099941 0.4049199844525861 1.0 0.8962367392438162 10 Q15056,P53701 2 +Abnormal shoulder physiology 0.5989742264534494 0.832634535184026 0.405050875630156 1.0 0.8962367392438162 4 O75844,P02545 2 +Delayed eruption of permanent teeth 0.5561983051177979 0.8325928202755541 0.405074409589615 1.0 0.8962367392438162 5 P21281,Q5JRA6,Q96L73 3 +Fetal ultrasound soft marker 0.376959461972144 0.8312905144172799 0.4058095318794015 1.0 0.8973516801792949 21 O75381,P56589,P22681,Q13501,P40855,P61978 6 +Cold induced muscle cramps 0.7174020340197396 0.8288911775024964 0.4071659881018536 1.0 0.8974584917330082 3 P23786 1 +Abnormal circulating methionine concentration 0.5200626207810093 0.8271629774093797 0.4081446927649685 1.0 0.8979045305239449 6 P55263 1 +Nuclear cataract 0.5546674999491723 0.8258208857312372 0.408905704514134 1.0 0.8979045305239449 5 P08670 1 +Abnormality of the proximal phalanx of the thumb 0.7162959794933748 0.8248087315551025 0.4094801886903101 1.0 0.8979045305239449 3 Q15233 1 +Short middle phalanx of finger 0.5187749748369991 0.8211040911017093 0.4115869799199629 1.0 0.8979045305239449 6 Q9UHX1 1 +Absent eyebrow 0.5184556018173809 0.8196021535867538 0.4124429455505725 1.0 0.8979045305239449 6 O75844,P02545 2 +Alopecia totalis 0.5184556018173809 0.8196021535867538 0.4124429455505725 1.0 0.8979045305239449 6 O75844,P02545 2 +Retinal vascular tortuosity 0.4009662671854984 0.8186205965257594 0.4130029121064615 1.0 0.8984354393957726 16 Q8WYQ5,P21964,Q15056,P00846 4 +Epiretinal membrane 0.7144635317551953 0.8180535844334007 0.4133265908451138 1.0 0.8987203821452732 3 P25054 1 +Orthostatic hypotension due to autonomic dysfunction 0.4480956936987743 0.8164883427968381 0.4142208880741616 1.0 0.8993343007766978 10 O43681,P20700 2 +Acanthocytosis 0.5522711950220529 0.8152356109766312 0.4149374575045013 1.0 0.900124791535346 5 Q05682 1 +Abnormal blistering of the skin 0.3613954736959542 0.814620668981373 0.4152894756246974 1.0 0.9004696021913476 23 P36551,O95453,P22681,O95155,Q01130,Q06136,Q9NZ08 7 +Abnormal peripheral nervous system morphology 0.2683874808490135 0.8086798916250414 0.4186992974854984 1.0 0.9037968732563708 175 Q9UHX1,P00846,Q9NR77,Q9BQT8,Q13501,Q13148,O95831,P06753,P22626,P20700,P25054,Q9Y619,P41440,Q15067,O43681,Q9Y5Y0,P31749,Q9H9S5,Q16637,P51812,O75381,Q15043,P35637,O95721,Q8IY17,Q969G3,Q99720,P56589,Q6DKK2,P40855 30 +Cerebellar cortical atrophy 0.711283822682779 0.8063573503394517 0.4200368311583666 1.0 0.9037968732563708 3 O75845,O75312 2 +Mottled pigmentation 0.5924821315570459 0.8058943834757109 0.4203037500059352 1.0 0.9037968732563708 4 O75844,P02545 2 +Death in adulthood 0.4055294313547385 0.8054065427572337 0.4205851173994306 1.0 0.9037968732563708 14 P51812 1 +Urinary incontinence 0.3086340811984611 0.8043183245099021 0.4212131574025743 1.0 0.9037968732563708 49 P51812,Q969G3,Q99720,P35637,O43681,Q9Y5Y0,P31749 7 +Meningocele 0.4283574519878971 0.803778221426831 0.4215250696363837 1.0 0.9039047930041808 11 O75845,Q9H9S5,Q10713 3 +Elevated hemoglobin a1c 0.5911845667754815 0.8005668000496868 0.4233824772536994 1.0 0.9051438330154356 4 Q9UKG1,O75431 2 +Abnormal tissue metabolite concentration 0.398151333356255 0.8000424491703564 0.4236862032522517 1.0 0.9051438330154356 16 O43681,O75381,P56589,P40855 4 +Hand oligodactyly 0.7094661665705835 0.7996861625613864 0.4238926521018211 1.0 0.9051438330154356 3 Q15427 1 +Kyphoscoliosis 0.3014745227276643 0.799425750808847 0.4240435838633634 1.0 0.9051438330154356 57 Q96AY3,Q04721,P51812,P02545,O75489,O75844,Q8N0X7,Q96L58,Q9NR77,P57740,Q9NWM8,Q8NCH0,P06753,P31749,Q9H9S5,Q15233 16 +Intermittent diarrhea 0.5479540315919996 0.7962149440184617 0.4259071130088059 1.0 0.9070460160151008 5 Q9UER7 1 +Abnormal circulating aspartate family amino acid concentration 0.4631965799105312 0.7949962124352038 0.4266157053738113 1.0 0.9076693959474812 8 P55263 1 +Lower limb muscle weakness 0.3086447983602264 0.7937838593997766 0.4273212706330787 1.0 0.9079720459120224 47 Q8IY17,P02545,O00400,Q969G3,P00846,Q9NR77,P06753,P31749,P37198,Q12768 10 +Arthrogryposis multiplex congenita 0.3235750846344054 0.7932693022750908 0.4276209379766467 1.0 0.9079720459120224 39 Q96AY3,O75844,Q99567,Q15392,P42356,Q8NCH0,Q9HD42,P06753 8 +Tetraparesis 0.3247443461161826 0.791531098524169 0.4286341361280881 1.0 0.9079720459120224 38 O95630,P00846,P35637,Q13501,Q13148,Q9H9P8,P37198,P20700 8 +Abnormality of bladder morphology 0.4433644418980973 0.7902902756695115 0.4293582645803036 1.0 0.9079720459120224 10 Q9NWM8 1 +Hypermethioninemia 0.5458854263600126 0.787124734835983 0.4312088511353193 1.0 0.9079720459120224 5 P55263 1 +Flattened femoral head 0.6917985611510766 0.7850656653830892 0.4324150692101911 1.0 0.9084796893951284 2 P16278 1 +Photoreceptor layer loss on macular oct 0.6915107913669041 0.7839479384704412 0.4330706591658415 1.0 0.9085018946074528 2 P04439 1 +Abnormal optical coherence tomography 0.6915107913669041 0.7839479384704412 0.4330706591658415 1.0 0.9085018946074528 2 P04439 1 +Pseudoarthrosis 0.5870680250946269 0.7837043722927588 0.4332135963994372 1.0 0.9085018946074528 4 O75844 1 +Alveolar ridge overgrowth 0.7049911317581372 0.7833095082371881 0.4334453810301628 1.0 0.9085794414043504 3 Q15392 1 +Skeletal dysplasia 0.3071062829885476 0.7810874495879561 0.4347510629169941 1.0 0.9088655120774812 48 Q04721,Q8WVQ1,O75381,P56589,Q96L58,Q9Y2U8,O94761,Q15427,P40855,O95831,P31749,Q96HY6 12 +Peripheral axonal degeneration 0.2852162106080347 0.7768126850027446 0.437269291666881 1.0 0.9114263379853176 77 Q8IY17,P00846,Q15067,Q9BQT8,Q6DKK2,O95831,P22626 7 +Megaloblastic anemia 0.4594711640774234 0.775584914285572 0.4379941104816636 1.0 0.9114263379853176 8 P00374 1 +Sloping forehead 0.3006154379696118 0.7754148234671756 0.4380945786700401 1.0 0.9114263379853176 56 O75845,O95630,Q9H9S5,Q9UPP1,Q08J23,Q8NG31,Q16625,P38398,Q9BXW9,P23786,P57740,Q86XL3,P98175,Q15058 14 +Large hands 0.4007646025007909 0.7752869154367168 0.4381701393208181 1.0 0.9114263379853176 14 P51812 1 +Abnormal femoral head morphology 0.3631278337260832 0.7747008550681159 0.4385164456344452 1.0 0.9114263379853176 22 Q6NUQ1,Q8WVQ1,O75431,P16278,O95831,Q96L58 6 +Abnormality of the periorbital region 0.2841461918503736 0.7704967252975774 0.4410052968034303 1.0 0.9129377293791386 74 P07437,P51812,Q9UPP1,Q08J23,P28070,O75381,P56589,P38159,P40855,P98175,Q8N1F7 11 +Clonic seizure 0.5830693924560946 0.7673847549076568 0.4428527899107077 1.0 0.9146380831230476 4 P07602,O14936,Q01082 3 +Temporal pattern 0.4573243925949198 0.7644282588637242 0.4446120739076196 1.0 0.9147202085157202 8 O60313,Q9NR77,Q12768 3 +Sparse lateral eyebrow 0.4563036511348065 0.7591313216976013 0.4477740041983367 1.0 0.9176519562982228 8 Q00577,P61978,Q08J23 3 +Type 1 muscle fiber atrophy 0.482274769478892 0.7554062323974828 0.450005274856629 1.0 0.9185305474487664 7 P06753,P61978 2 +Disproportionate short limb short stature 0.3664174041037874 0.7522249656714646 0.4519157824178279 1.0 0.9196150565752412 21 Q8WVQ1,O00116,O75718,Q32P28,O15228,Q03164,Q15392 7 +Cystic hygroma 0.4816198524432674 0.7522193854670473 0.4519191376298233 1.0 0.9196150565752412 7 P22681,P61978 2 +Intrinsic hand muscle atrophy 0.5783472523544979 0.7481925653312952 0.4543440147851434 1.0 0.9215329622720648 4 Q9NR77 1 +Ventricular tachycardia 0.3934763749380074 0.7478191888200328 0.4545692261977943 1.0 0.9215329622720648 15 O43772,P23786 2 +Aplasia hypoplasia involving bones of the lower limbs 0.282132894535382 0.7472654842601296 0.4549033227829835 1.0 0.9216018410624878 98 Q96AY3,Q9UHX1,Q03164,O95831,P13073,Q14320,P25054,P02545,Q9Y619,Q08J23,O00116,O95155,P00813,Q96HY6,Q04721,Q8WVQ1,Q69YQ0,O96028,Q8N0X7,Q15427,Q96L58 21 +Abnormal pleura morphology 0.3528968962654575 0.7469884233274304 0.4550705488779822 1.0 0.9216018410624878 23 O15460,P22681,P14174,Q8NCH0,Q9NZ08 5 +Central scotoma 0.4354405971022469 0.7466585084385317 0.4552697212636789 1.0 0.9216050260302944 10 P00846 1 +Cardiac conduction abnormality 0.3241235881707287 0.745210393445572 0.456144540686259 1.0 0.9225750814226852 34 O95169,O43772,P00846,P23786 4 +Hypoplasia of the musculature 0.5361893887689164 0.7447389055205148 0.4564295747004421 1.0 0.9227239012729382 5 Q9NR77 1 +Papule 0.3760469238951084 0.7418668590085888 0.4581680070388345 1.0 0.9232590869453412 19 Q9Y2U8,O75844,P31749,Q9NZ08 4 +Abnormal macroscopic urine appearance 0.3650063209681874 0.7417079210991239 0.4582643195279727 1.0 0.9232590869453412 21 P36551,P23786,Q14C86,Q8NFH4,Q8N1F7 5 +Progressive inability to walk 0.3521447334529467 0.7410329506759832 0.4586734615956833 1.0 0.923366920185586 23 Q15043,P00846,Q9H9S5,P37198 4 +Abnormality of fundus pigmentation 0.5759266623106463 0.7383898981924577 0.4602775514276032 1.0 0.9253165947665264 4 Q9Y619 1 +Polyneuropathy 0.3481887836910764 0.7357902088044247 0.4618583807817578 1.0 0.9274062052521418 25 O95831,P00846 2 +Decreased plasma carnitine 0.3989191729572651 0.7341814812665325 0.4628381384834514 1.0 0.9283467573712536 12 P23786 1 +Diminished movement 0.3797221809196581 0.7338042648327373 0.463068040911593 1.0 0.9283467573712536 18 P51114,O95831,P06753,Q6Y7W6 4 +Visual field defect 0.3032781012894414 0.7331902361550989 0.4634424096207588 1.0 0.9284774048415888 47 Q9H061,O75381,P00846,P56589,O15460,P40855,Q9Y5Y0,P31749 8 +Alternating esotropia 0.6910267229063329 0.7326737220097559 0.463757454995211 1.0 0.9287096479594952 3 P20700 1 +Abnormal pericardium morphology 0.432612661814035 0.7311691606241136 0.4646758345853414 1.0 0.92895331869097 10 Q14108,P14174,Q9NZ08,O15460 4 +Abnormal erythrocyte sedimentation rate 0.4507618301529807 0.7304657925942811 0.4651055150443242 1.0 0.929015898144209 8 O15460,P28070 2 +Focal dystonia 0.3500443653489037 0.7244317661708503 0.468800703624199 1.0 0.9319963087668504 23 Q15043,Q9NQZ5,P35637,Q99720 4 +Increased bone mineral density 0.3422769533515115 0.7206941367162866 0.4710977206470113 1.0 0.9325462380174516 27 Q15056,Q13126,P02545,Q14108,Q15043,Q15392,Q9Y2U8,Q13501,Q14191 9 +Abnormal preputium morphology 0.4483313478507547 0.7179460639521991 0.4727905438087139 1.0 0.9339474930067032 8 P38398,Q9BXW9,Q96L73 3 +Long fingers 0.2816024362395687 0.7169403042245259 0.4734109315976522 1.0 0.9339474930067032 81 O96028,P07437,Q9UPP1,P51812,Q9UHX1,Q969G3,P55795,P42892,Q03164,P23786,P21964,P57740,Q03252,Q8NCH0,Q06136,Q96L58 16 +Joint subluxation 0.4962404351197838 0.7160754693674422 0.4739447498493006 1.0 0.9339474930067032 6 Q9UHX1,Q96L58 2 +Cutaneous abscess 0.6851300553384502 0.7115228101514658 0.4767603209624145 1.0 0.9339474930067032 3 O95394 1 +Congenital contracture 0.3013458470618775 0.7114738091875367 0.4767906751260344 1.0 0.9339474930067032 47 Q96AY3,O75844,Q99567,Q15392,P42356,Q8NCH0,Q9HD42,P06753,Q9H9S5 9 +Glomerulopathy 0.428998352671885 0.7114418550123752 0.4768104700467281 1.0 0.9339474930067032 10 Q14108,Q03252,Q9NZ08 3 +Weight loss 0.2812437711006826 0.7104353668434205 0.4774341979760561 1.0 0.9339474930067032 82 Q13423,Q6UN15,Q06136,Q99720,P42892,P35637,Q9BXW9,P06753,O15460,P22681,Q6Y7W6,Q01130,O75844,P31749,Q9NZ08 15 +Broad palm 0.4373677263581702 0.7072061388542201 0.4794383841846419 1.0 0.9339474930067032 9 O95831 1 +Aplasia hypoplasia affecting the fundus 0.3401435050570232 0.7027844407777526 0.4821900950766635 1.0 0.9339474930067032 27 P37268,P25054,Q9UHX1,O95721,P61978 5 +Limb muscle weakness 0.2806418754528383 0.702159458703837 0.4825797253165813 1.0 0.9339474930067032 90 Q16637,Q8IY17,Q13126,O00400,P36551,Q969G3,Q99720,P00846,Q15067,Q9NR77,Q9BQT8,Q13501,P31749,P37198 14 +Abnormal placental size 0.56612679144042 0.6989658810620861 0.4845733535467367 1.0 0.9339474930067032 4 O75844 1 +Hemianopia 0.4266212382831501 0.6985120423741994 0.4848570294487828 1.0 0.9339474930067032 10 P31749 1 +Chorioretinal dysplasia 0.4918292143991435 0.6957762509439268 0.4865689643836841 1.0 0.9339474930067032 6 P53701 1 +Abnormal csf protein level 0.3880643880073042 0.6957581320329538 0.4865803132613271 1.0 0.9339474930067032 14 O43681,Q16625,P20700 3 +Abnormality of the metaphysis 0.2949229877601204 0.6946411406417731 0.4872802230442943 1.0 0.9339474930067032 55 Q13126,Q04721,Q8WVQ1,P48735,O95453,Q96L58,Q9Y2U8,O94761,Q96L73,O95831,P00813,Q96HY6 12 +Absent epiphyses 0.4910326410240259 0.6921211147676517 0.4888612727305128 1.0 0.9339474930067032 6 Q7LGA3,O00443,O60568,Q8WVQ1 4 +Multifactorial inheritance 0.3870616184974825 0.6895321318737917 0.4904884599355796 1.0 0.9339474930067032 14 P42892,P35611,P38398,P10321 4 +Abnormality of the elbow 0.2833344711760949 0.6894831622728634 0.490519265580998 1.0 0.9339474930067032 64 P37268,Q96AY3,Q04721,P25054,P02545,Q9Y619,Q8WVQ1,Q03164,P23786,P22681,P57740,Q15427,P06753,Q96L58 14 +Premature rupture of membranes 0.490222689873963 0.6884079786677341 0.4911959008243964 1.0 0.9339474930067032 6 O75844 1 +Periorbital fullness 0.351726615385064 0.6873943073418846 0.491834283959851 1.0 0.9339474930067032 22 P51812,P38159,P40855 3 +Arterial stenosis 0.3768698341923462 0.6856865974491386 0.4929107601455924 1.0 0.9339474930067032 17 P34913,P02545 2 +Decreased proportion of cd4 positive helper t cells 0.4678242890952137 0.6855777848968121 0.4929793942523837 1.0 0.9339474930067032 7 O95394,Q13432 2 +Abnormally lax or hyperextensible skin 0.2989872299207152 0.6850474377463264 0.4933139868772158 1.0 0.9339474930067032 47 P07437,Q15056,Q9UHX1,P51812,Q96L73,O95453,O75787,Q9NWM8,Q8NCH0,O96000,Q96L58 11 +Abnormality of cranial sutures 0.2781018683734423 0.6849813482955133 0.4933556908096652 1.0 0.9339474930067032 98 Q96AY3,O75718,Q32P28,O94761,Q96L73,O95831,P98175,P02545,Q9Y619,Q08J23,P21964,O95155,Q8NCH0,P31749,O75845,Q04721,P51812,O75381,Q9Y2U8,Q69YQ0,O15047,P40855,O75844,Q96L58,P61978 25 +Facial edema 0.3305339639878644 0.6843708548771024 0.4937410151684349 1.0 0.9339474930067032 30 Q15056,P28070,Q14C86,P57740,Q8NFH4,Q8N1F7 6 +Pelvic girdle muscle weakness 0.4068491652256951 0.6802811801206237 0.4963264386652191 1.0 0.9339474930067032 11 P06753,O14979 2 +Abnormality of t cell physiology 0.3855096627628796 0.6799134323990572 0.4965592758974175 1.0 0.9339474930067032 14 O95394,P21964,Q96MG7,Q8WYQ5,P00813 5 +Abnormal circulating gonadotropin concentration 0.3797311790031676 0.6798313787389704 0.496611235618706 1.0 0.9339474930067032 16 Q8IY17,P31749 2 +Abnormal t cell proliferation 0.6760383833571393 0.6792061890721196 0.4970072263560399 1.0 0.9339474930067032 3 O95394 1 +Reduced antigen specific t cell proliferation 0.6760383833571393 0.6792061890721196 0.4970072263560399 1.0 0.9339474930067032 3 O95394 1 +Absence of pubertal development 0.5204961400891215 0.677022811165615 0.4983914813416601 1.0 0.9339474930067032 5 O75844 1 +Corneal opacity 0.2823643004381017 0.6767299741931884 0.4985772949129172 1.0 0.9339474930067032 64 O96028,P53701,O75844,O75381,Q16625,P56589,Q06136,P34913 8 +Palmar pits 0.663309352517983 0.67639820067198 0.4987878593527544 1.0 0.9339474930067032 2 P16615 1 +Akinesia 0.4313738893311619 0.6756601687578533 0.4992564305100959 1.0 0.9339474930067032 9 P51114,Q6Y7W6 2 +Aplasia hypoplasia of the breasts 0.4312505700099092 0.6750136270139365 0.4996671072730654 1.0 0.9339474930067032 9 P02545,Q9Y619 2 +Abnormal clavicle morphology 0.3422551929276928 0.674420449750332 0.5000440451456172 1.0 0.9339474930067032 24 Q96AY3,O75844 2 +Abnormal renal tubule morphology 0.3316732722759008 0.6710939905240152 0.5021606550334772 1.0 0.935708068348437 29 P00846,P23786 2 +Choroidal neovascularization 0.6607194244604291 0.6667388037752463 0.5049389880911692 1.0 0.9362007319323944 2 P04439 1 +Abnormal morphology of the choroidal vasculature 0.6607194244604291 0.6667388037752463 0.5049389880911692 1.0 0.9362007319323944 2 P04439 1 +Abnormal brainstem mri signal intensity 0.3489583605476201 0.6663982681034306 0.5051565692056754 1.0 0.9362007319323944 22 Q9Y375,Q9P032,O43676,O75489,Q8N183,P49792,Q96CU9,O95831,O96000 9 +Ectopic kidney 0.3652086395545042 0.6660674066001168 0.5053680164257481 1.0 0.9362007319323944 19 Q15056,P25054,Q9UHX1,Q9BXW9,Q9Y2U8 5 +Sepsis 0.3545377233698095 0.6642798983398851 0.5065111842430727 1.0 0.9362007319323944 21 P42892 1 +Abnormal eating behavior 0.3393653121115174 0.6642630651932013 0.5065219560290473 1.0 0.9362007319323944 25 Q4J6C6,Q9UJS0,Q969G3,P49366,O95155 5 +Astrocytoma 0.4200674412591318 0.6630625277772472 0.5072905086571184 1.0 0.9362007319323944 10 P25054,P48735 2 +Lagopthalmos 0.6709892817964911 0.6614231771801643 0.5083409663557874 1.0 0.9362007319323944 3 O75844 1 +Abnormal thalamic size 0.5566361869816472 0.6612237258137045 0.5084688479412469 1.0 0.9362007319323944 4 P11166,Q9H9S5 2 +Aspiration pneumonia 0.3371623390997072 0.6610806771768071 0.5085605763581089 1.0 0.9362007319323944 26 Q969G3,P06753,P78318,O95721,Q00577,P20700 6 +Adrenal hypoplasia 0.4285397686754576 0.6608280873665138 0.5087225680692198 1.0 0.9362007319323944 9 O75844,Q12768 2 +Neoplasm of the thyroid gland 0.3326709798200445 0.6588567927058623 0.5099877337014069 1.0 0.9362007319323944 28 P25054,P02545,Q969G3,P42892,P31749 5 +Bowel diverticulosis 0.4281507970406523 0.658796880159485 0.510026210990965 1.0 0.9362007319323944 9 Q15056,P31749 2 +Cerebral inclusion bodies 0.3837801277547067 0.6551878710253249 0.5123468024784965 1.0 0.9362007319323944 13 P22626,P05067,Q6Y7W6 3 +Bone pain 0.3343446042813751 0.654381553037582 0.5128660160543899 1.0 0.9362007319323944 27 Q04721,Q6UN15,Q14108,P48735,P22681,Q13501,Q01130 7 +Hoarse cry 0.6569784172661842 0.6528579671168533 0.5138478490127112 1.0 0.936565517583648 2 Q69YQ0 1 +Weakness of facial musculature 0.2820460519298265 0.6528297700449984 0.5138660290515771 1.0 0.936565517583648 63 Q9UHX1,P51812,Q969G3,Q15043,O75381,P56589,Q9BQT8,Q13501,P40855,P06753,P31749 11 +Slowly progressive 0.2883774519952855 0.6517985233723926 0.5145311543622331 1.0 0.9366796658647364 58 O00429,Q9P0J0,O60318,Q9NR77,O95831,O14979,Q8NCE2,Q15120,P02545,P41440,Q9Y5Y0,Q6UWE0,Q16637,Q92734,P46976,Q8IV08,Q99720,O75787,O75190 19 +Congenital muscular dystrophy 0.6680191396640938 0.6510199420142182 0.5150336139079896 1.0 0.937228550630848 3 Q9H9S5 1 +Brisk reflexes 0.3374994134172399 0.6492575907967173 0.5161718925992602 1.0 0.93794201185236 25 Q99720,P35637,O60508,Q10713 4 +Transposition of the great arteries 0.4346785930227062 0.6482895292501047 0.5167977050489756 1.0 0.9383225792686956 8 P57076,O75844 2 +Generalized lipodystrophy 0.5532598807073809 0.6479100932220198 0.5170431022128104 1.0 0.9383225792686956 4 O75844,P02545 2 +Ectropion of lower eyelids 0.6555395683453209 0.6475422383585429 0.5172810669545647 1.0 0.9383892704593486 2 O60716 1 +Lipoma 0.4341499606755844 0.6456175297417196 0.5185270818472634 1.0 0.9386669690025532 8 P31749 1 +Abnormal thyroid morphology 0.3047458248632251 0.6452780502794035 0.5187470143450423 1.0 0.9386669690025532 42 Q969G3,P42892,P48735,P00813,P31749 5 +Hemiplegia hemiparesis 0.3074368804744233 0.6429457012008342 0.5202593336083083 1.0 0.938677783519434 40 Q8IY17,Q969G3,P31749,O95155,Q9Y3Z3,Q15051,Q9NZ08 7 +Writer s cramp 0.6541007194244575 0.642239563727255 0.520717648245872 1.0 0.9387812568298208 2 Q9ULV3 1 +Decreased circulating androgen concentration 0.4000502306897004 0.641919996337629 0.5209251300399866 1.0 0.9387924290983376 11 P31749 1 +Abnormal t cell morphology 0.3658788190008815 0.6398433786366927 0.5222744278786684 1.0 0.9394091521890126 18 Q13546,O95394,O75787,P00813,Q13432 5 +External ear malformation 0.3657166137597095 0.6387539915316506 0.522982982919026 1.0 0.9399586251770086 18 P07437,O75381,P56589,P38398,Q9BXW9,P40855,Q8NCH0 7 +Peritonitis 0.3690642305243608 0.6343316327243326 0.5258644166898758 1.0 0.9407717333230432 17 P57740,Q8N1F7,Q14C86,Q8NFH4 4 +Impairment of activities of daily living 0.2840949374784153 0.6275466123181193 0.5303009917922097 1.0 0.941809866025517 60 P51812,Q99720,P35637,O43681,Q9Y5Y0,P20700 6 +Impaired mastication 0.47644538006505 0.6258110254643671 0.5314388992365764 1.0 0.941809866025517 6 O15460 1 +High hypermetropia 0.3969459500675611 0.6245356046133673 0.5322758952030857 1.0 0.941809866025517 11 O95155,Q15056,P68371 3 +Gangrene 0.3804798072710315 0.6243622044549224 0.5323897407191911 1.0 0.941809866025517 12 Q6UN15,Q9NZ08 2 +Epidermoid cyst 0.6603339090385624 0.6243091734479402 0.5324245605787477 1.0 0.941809866025517 3 Q9H488,P25054 2 +Short sternum 0.6600576994649552 0.6233549317661323 0.5330513072236411 1.0 0.941809866025517 3 P98175 1 +Limb dystonia 0.3736883650810483 0.6227363880418392 0.5334577664313289 1.0 0.941809866025517 15 P35637 1 +Abnormal trabecular bone morphology 0.454111594485191 0.6204119277285399 0.5349866215718104 1.0 0.942725436633495 7 Q04721,O95453 2 +Rheumatoid factor positive 0.5461055275285394 0.6199100406379777 0.5353170149477839 1.0 0.942725436633495 4 O95394 1 +Abnormal renal cortex morphology 0.2857593310652686 0.6197412212499583 0.535428172232052 1.0 0.942725436633495 58 Q8N1F7,Q9NZ08,Q14108,P00846,Q16134,O95394,Q14C86,Q03252,Q8NFH4,P00813,Q9Y2Z9 11 +Posterior fossa cyst 0.5460585890415272 0.6197273220340735 0.5354373245373345 1.0 0.942725436633495 4 Q9H9S5,Q9UHX1 2 +Premature osteoarthritis 0.6471942446043136 0.6169735682634646 0.5372521599903126 1.0 0.944494562455642 2 Q96HY6 1 +Teratoma 0.5449439604723366 0.6153922646009787 0.5382956986543803 1.0 0.9446342234245776 4 O95999,Q96L73 2 +Cutis marmorata 0.357835776865823 0.6152025314774103 0.5384209762041947 1.0 0.9446342234245776 19 P51812,Q08J23 2 +Abnormality of the peritoneum 0.3418570780105034 0.6129693197445225 0.5398966261650859 1.0 0.9446342234245776 22 Q01844,Q14C86,P57740,Q8NFH4,Q8N1F7 5 +Abnormality of thalamus morphology 0.3574111233675425 0.6122925687598497 0.5403442054441763 1.0 0.9446342234245776 19 Q9UPT5,Q969G3,Q13057,O95169,P49792,P11166,O00443,P31749,Q9H9S5 9 +Reduced subcutaneous adipose tissue 0.4187611728769379 0.6101124721786019 0.5417873052485942 1.0 0.9446342234245776 9 O75844 1 +Abnormality of the bladder 0.2513958133650098 0.6055652289155184 0.5448034976542748 1.0 0.9446342234245776 133 Q9UHX1,Q9NR77,O94761,Q86XL3,Q13501,Q96L73,P22626,Q12768,P20700,O95630,O43681,P21964,Q9Y5Y0,Q8NCH0,P31749,Q15058,Q15056,Q9UJS0,P51812,Q8NG31,P35637,Q3ZCQ8,O43379,P11166,Q6Y7W6,Q969G3,Q99720,Q8N0X7,P56589,Q9NWM8,P61978 31 +Abnormal cranial nerve physiology 0.2733100440787685 0.6050509888309165 0.5451451179705802 1.0 0.9446342234245776 78 P51812,Q9UHX1,Q969G3,O75381,Q15043,P56589,P48735,Q9BXW9,P42356,Q9NR77,O95155,P40855,Q13501,P06753,P31749,Q9H9S5,Q9NZ08 17 +Increased circulating prolactin concentration 0.4177450030359502 0.6048861706498943 0.5452546325941068 1.0 0.9446342234245776 9 P31749 1 +Ascites 0.3260067065643549 0.6027867824163815 0.5466505408325273 1.0 0.9446342234245776 28 Q01844,Q14108,P22681,O15118,O95235,O75787,Q01130 7 +Respiratory distress 0.2853864208600613 0.6027408952486789 0.5466810715110666 1.0 0.9446342234245776 57 Q9UHX1,Q9Y619,O95169,P00846,P23786,O95831,P53701 7 +Prominent crus of helix 0.6431654676258963 0.6023829093084323 0.5469192837254586 1.0 0.9446342234245776 2 Q7LGA3 1 +Metatarsus valgus 0.6539521662270131 0.602367732104399 0.5469293841272191 1.0 0.9446342234245776 3 P31749 1 +Joint stiffness 0.2831436730639773 0.6011724559817152 0.5477251280977333 1.0 0.9446342234245776 59 Q96AY3,Q15056,P02545,P48735,P16278,Q9Y2U8,O94761,O95155,O15460,Q15427,Q96L73,O75844,P31749,Q14191,P54802 15 +Slurred speech 0.4250433714459746 0.5999195336759948 0.5485598635123792 1.0 0.9447870027406708 8 O75787,Q8N0X7 2 +Abnormal thyroid stimulating hormone level 0.6414388489208604 0.5961642901834576 0.5510654788138696 1.0 0.9463068457981914 2 O14654 1 +Abnormality of the female genitalia 0.2475493635758439 0.5921931465052803 0.5537212582404527 1.0 0.9487844507069182 144 P04150,P38398,O60318,P25054,P02545,Q9Y619,Q08J23,P31939,Q9BXW9,P21964,O95155,P31749,P31751,Q15056,P51812,Q01844,O75381,Q15392,P48735,Q69YQ0,P53701,Q15051,O96028,O75312,P56589,O95453,P57740,Q03252,Q15427,P40855,O75844,Q14191,Q16740 33 +Abnormality of the lymph nodes 0.2902440121540751 0.5880160976403551 0.5565214878718767 1.0 0.9493365179749008 47 P33991,Q01844,Q6UN15,P28070,O15460,P22681,P14174,Q01130,P00813,Q9NZ08 10 +Abnormal systemic blood pressure 0.2719760131423786 0.587811544084796 0.5566587945763488 1.0 0.9493365179749008 97 P42892,P49366,P04150,Q10713,P20700,Q13423,P02545,P35610,O43681,P21964,P22681,Q15056,Q04721,P35611,Q9Y2U8,Q6Y7W6,Q01130,Q15051,Q9UER7,O43772,P36551,O75844 22 +Hallucinations 0.2901905734378653 0.587428174363569 0.5569161762119852 1.0 0.9493365179749008 47 Q9UJS0,Q9BQE5,P36551,P35637,O75503,O43681,Q13501,Q6Y7W6,Q6DKK2,P05067,P50897 11 +Acanthosis nigricans 0.3900988727884971 0.5865098354580687 0.5575329540053067 1.0 0.9493365179749008 11 P31751,P02545,P28070 3 +Neoplasm of fatty tissue 0.3738048629289693 0.5853979939339488 0.5582801373294215 1.0 0.9493365179749008 12 P31749,P25054 2 +Oligodactyly 0.4054603129727598 0.5852547895026937 0.5583764094097567 1.0 0.9493365179749008 10 P25054,Q15427 2 +Progressive gait ataxia 0.3737410412869102 0.5850277884245079 0.558529032016108 1.0 0.9493365179749008 12 P00846 1 +Retrognathia 0.2726580590878775 0.5836667844102238 0.5594445185665968 1.0 0.9498541079703704 85 P37268,Q4J6C6,Q9UHX1,Q9Y619,O75844,Q15392,Q16625,Q8NCH0,Q8WYQ5,P53701 10 +Abnormality of the inner ear 0.4049410019630172 0.5825229373794337 0.5602144960342477 1.0 0.9503553014112652 10 P31749,Q9Y619 2 +Deep palmar crease 0.3729842067514491 0.5806412077784803 0.5614822934171153 1.0 0.951927814066676 12 Q69YQ0,P98175,P61978 3 +Segmental peripheral demyelination remyelination 0.4450778303654057 0.5781831466322281 0.5631404759317089 1.0 0.953699048564085 7 P00846 1 +Bowing of the arm 0.4448565038369698 0.5771563189624083 0.5638338619397278 1.0 0.9545267267103053 7 Q96L58,Q32P28 2 +Generalized hirsutism 0.3248720797601664 0.5763380783995444 0.5643866896194982 1.0 0.9546493941174532 27 P07437,Q04721,P02545,Q03252,O95155,Q06136,P31749 7 +Central apnea 0.4202461492058378 0.5761176400039475 0.5645356689602927 1.0 0.9546493941174532 8 P11166,P07602,Q10713 3 +Abnormal carotid artery morphology 0.3631748478064827 0.5744615866346179 0.5656554876461857 1.0 0.9554174976666698 16 Q15056,P02545,Q9BXW9,O75844 4 +Abnormal circulating estrogen level 0.3709422373180805 0.5688390807467409 0.569465350380107 1.0 0.9559358840556677 12 Q969G3,P31749 2 +Limited wrist movement 0.4945295311804817 0.5680020414240896 0.5700335817688509 1.0 0.9559358840556677 5 O75844 1 +Supernumerary bones of the axial skeleton 0.4943490537584531 0.5672598972889809 0.5705376187544908 1.0 0.9559358840556677 5 Q9UHX1 1 +Absent forearm bone 0.4941481058180944 0.5664338553511251 0.5710988856162997 1.0 0.9559358840556677 5 Q15427,Q9BXW9 2 +Abnormality of the crus of the helix 0.6433506044904903 0.5664310735667308 0.5711007761862965 1.0 0.9559358840556677 3 P08754,Q7LGA3 2 +Abnormality of cartilage of external ear 0.6433506044904903 0.5664310735667308 0.5711007761862965 1.0 0.9559358840556677 3 P08754,Q7LGA3 2 +Fever 0.2713385981911334 0.5646562970023842 0.5723075653680663 1.0 0.9559358840556677 90 Q8N1F7,Q8NFH4,Q6UN15,Q13546,P28070,P00846,P23786,Q14C86,O15460,Q9NR77,P61978,Q9Y3Z3,P14174,Q01130,P00813,Q9NZ08 16 +Abnormal ciliary body morphology 0.6322302158273351 0.5633624296234272 0.5731881150045679 1.0 0.9559358840556677 2 Q99496 1 +Metamorphopsia 0.6322302158273351 0.5633624296234272 0.5731881150045679 1.0 0.9559358840556677 2 Q99496 1 +Uveal melanoma 0.6322302158273351 0.5633624296234272 0.5731881150045679 1.0 0.9559358840556677 2 Q99496 1 +Choroidal melanoma 0.6322302158273351 0.5633624296234272 0.5731881150045679 1.0 0.9559358840556677 2 Q99496 1 +Mydriasis 0.6322302158273351 0.5633624296234272 0.5731881150045679 1.0 0.9559358840556677 2 Q99496 1 +Inferior lens subluxation 0.6322302158273351 0.5633624296234272 0.5731881150045679 1.0 0.9559358840556677 2 Q99496 1 +Photopsia 0.6322302158273351 0.5633624296234272 0.5731881150045679 1.0 0.9559358840556677 2 Q99496 1 +Capillary hemangioma 0.3857015787780006 0.5623394421269642 0.5738847701879788 1.0 0.9559358840556677 11 O94761,P31749,Q9UHX1 3 +Aplasia hypoplasia of the ribs 0.3289619388533039 0.5607551502292157 0.5749644650306469 1.0 0.9559358840556677 23 Q9UHX1,Q9Y619,Q96L58,O95155,Q15427,Q96HY6,Q12768 7 +Vertebral arch anomaly 0.6416234887737373 0.5606403940299909 0.5750427086686289 1.0 0.9559358840556677 3 Q14807,Q96HY6 2 +Narrow vertebral interpedicular distance 0.6416234887737373 0.5606403940299909 0.5750427086686289 1.0 0.9559358840556677 3 Q14807,Q96HY6 2 +Hepatocellular adenoma 0.6416234887737371 0.5606403940299906 0.5750427086686292 1.0 0.9559358840556677 3 Q9UKG1,O00330 2 +Aplasia hypoplasia of the skin 0.2774292956394349 0.5597594513685378 0.575643524943535 1.0 0.9559358840556677 61 Q14191,O96028,Q13126,P02545,Q9Y619,O75844,Q15392,O95453,Q9Y2U8,Q9NWM8,Q8NCH0,P53701,Q96PU5,Q96L58 14 +Large placenta 0.6408186469548639 0.5579482380250945 0.5768797305823901 1.0 0.9559358840556677 3 O75844 1 +Ankylosis 0.4919598561211079 0.5574577958826009 0.5772146867327328 1.0 0.9559358840556677 5 O75844 1 +Obsessive compulsive trait 0.4918696332994821 0.557088470903533 0.5774669842283449 1.0 0.9559358840556677 5 Q06787,Q8WXI9,O75503 3 +Carcinoid tumor 0.5296370103239094 0.556658455179514 0.5777608068890976 1.0 0.9559358840556677 4 P25054,P02545 2 +Lambdoidal craniosynostosis 0.4917638096226489 0.556655361890904 0.5777629207371129 1.0 0.9559358840556677 5 P61978 1 +Oval face 0.4403812967210899 0.5564787229399448 0.5778836358142341 1.0 0.9559358840556677 7 Q9UHX1 1 +Glomerulonephritis 0.3396201577409637 0.556209875556364 0.5780673889175858 1.0 0.9559358840556677 21 O95394,Q14C86,Q03252,Q8NFH4,Q8N1F7 5 +Platyspondyly 0.3026488733149821 0.5543615509532722 0.5793314341068003 1.0 0.9561822136319764 36 O95831,Q96AY3 2 +Anterior open bite malocclusion 0.6293525179856084 0.5532422279143419 0.5800975547820428 1.0 0.9561822136319764 2 P08754 1 +Absent thumbnail 0.6293525179856084 0.5532422279143419 0.5800975547820428 1.0 0.9561822136319764 2 O14936 1 +Nyctalopia 0.3069836942972295 0.5524769266031687 0.5806216384804874 1.0 0.9561822136319764 33 O75381,P56589,P40855,Q9Y5Y0,Q13432 5 +Macrovesicular hepatic steatosis 0.4394408983935277 0.5521546901228537 0.5808423745992133 1.0 0.9561822136319764 7 P23786,Q9Y375,Q5XKP0 3 +Abnormal forearm bone morphology 0.3276967275570966 0.5511410966370173 0.5815369551370415 1.0 0.9561822136319764 23 P25054,Q32P28,P38398,Q9BXW9,Q15427,P98175,Q96L58 7 +Polymicrogyria 0.2702217999540937 0.5509863384100825 0.5816430397603987 1.0 0.9561822136319764 83 P37268,O75381,Q15392,Q16625,P56589,P23786,Q96JM3,P40855,O95721,Q01105,Q10713 11 +Weakness due to upper motor neuron dysfunction 0.2463886067044286 0.5500292158094536 0.5822993349730501 1.0 0.9561822136319764 147 P00846,P42356,Q9P0J0,Q13501,Q13148,O95831,Q9H9P8,P20700,Q13423,O95630,Q9Y619,O00400,Q8N183,P49902,O43681,O95155,Q9Y3Z3,P31749,Q9H9S5,P37198,Q9H0B6,P35637,Q15051,Q8IY17,O75489,Q969G3,P56589,Q6DKK2,Q96L58,Q9NZ08 30 +Abnormal branching pattern of the aortic arch 0.5274664745105297 0.5484582231056132 0.5833773074696968 1.0 0.9561822136319764 4 Q8WYQ5 1 +Eeg with focal spikes 0.458749081389404 0.5472231566465973 0.5842254290111557 1.0 0.9567978812632374 6 P42356,O75503 2 +Oligohydramnios 0.3010030959827383 0.5466085587536313 0.5846476878043179 1.0 0.9567978812632374 37 P51114,O15047,Q9UHX1,Q86YH6,P49366,P38398,Q9BXW9,P23786,Q96L58,Q07021,Q15058 11 +Congenital nystagmus 0.3547780289814595 0.5421646619329556 0.5877050769501411 1.0 0.9600898349896524 17 P00846 1 +Hypokinesia 0.3819028554642626 0.5416298265118152 0.5880735403566626 1.0 0.9603553894339896 11 O95831,P06753 2 +Abnormal parotid gland morphology 0.6247482014388459 0.5371846370601869 0.5911400821410724 1.0 0.9626666700788972 2 P16615 1 +Aplasia hypoplasia of the phalanges of the toes 0.4868064715642697 0.5364620283207179 0.5916392721984403 1.0 0.9628168756168052 5 P02545,P35453 2 +Autoimmune antibody positivity 0.3808057116558724 0.5356793686949207 0.5921801647392801 1.0 0.9633513388015356 11 O95394,P00813 2 +Aplasia involving bones of the extremities 0.5239814902976867 0.53536332711042 0.5923986439552971 1.0 0.9633707375897858 4 Q9BXW9 1 +Retinal dystrophy 0.2697437641344528 0.5318996262911327 0.5947955161418159 1.0 0.9636066919744116 65 Q8IY17,O75381,P00846,Q15067,P56589,P40855,Q9Y5Y0,P53701,Q15051 9 +Abnormal morphology of the radius 0.3586933796015664 0.5307105550302831 0.5956193705982096 1.0 0.9636066919744116 15 P25054,Q32P28,Q15427,P98175,Q96L58 5 +Chronic pulmonary obstruction 0.4853536880576516 0.530580598376659 0.5957094433091961 1.0 0.9636066919744116 5 P09601 1 +Short long bone 0.3000706602094072 0.5299490041775755 0.5961472884786705 1.0 0.9636066919744116 36 Q9UHX1,P25054,O00116,Q8WVQ1,O15228,P38398,Q9BXW9,Q96L58,O94761,Q15427,P98175,Q96HY6 12 +Aplasia hypoplasia involving the metacarpal bones 0.3171039602135333 0.5290383686383952 0.5967788337267468 1.0 0.9636066919744116 28 Q8WVQ1,P51812,Q32P28,Q9BXW9,Q96L58 5 +Spinal muscular atrophy 0.3638175260586099 0.5280586257628862 0.5974586462281348 1.0 0.9636066919744116 12 Q99720 1 +Ectopic calcification 0.2736048158296415 0.5277503751040414 0.5976726043584453 1.0 0.9636066919744116 62 O75845,Q14191,P02545,O00116,O15228,O75381,O75431,Q16625,P23786,P56589,O95453,Q9Y3Z3,Q96MG7,P40855,O75844,P05067 16 +Eeg with generalized slow activity 0.4020894519905137 0.5255638390695317 0.599191286917208 1.0 0.9644471564292176 9 P20700,O75503 2 +Occipital meningocele 0.5211463254162401 0.5247767110324817 0.5997384230510199 1.0 0.9644471564292176 4 Q10713 1 +Abnormal anterior chamber morphology 0.5208612943976078 0.5237157666930394 0.6004762477275005 1.0 0.9650658922815514 4 Q9NP72,Q8NCH0 2 +Abnormal thalamic mri signal intensity 0.4530786425219689 0.5225468674122459 0.6012896235084042 1.0 0.9653534557979356 6 P31749 1 +Elevated gamma glutamyltransferase level 0.5198617592742958 0.52000022161565 0.6030634206311518 1.0 0.9653534557979356 4 Q9UJS0 1 +Bladder neoplasm 0.4008803541705574 0.5195395225985506 0.6033845593640161 1.0 0.9653534557979356 9 P31749 1 +Abnormality of the musculature of the lower limbs 0.311506619487831 0.5195053355762523 0.6034083931219731 1.0 0.9653534557979356 30 P00846,Q9NR77,O14979,P43243,Q9H9S5,Q12768 6 +Fatigue 0.2682402910991635 0.5191612306242253 0.6036483122303811 1.0 0.9653534557979356 87 Q13148,Q13423,Q4J6C6,Q6UN15,Q70HW3,P35637,P04150,O15460,P22681,Q07021,Q13501,Q01130,Q15165,Q92804,P06753,Q9NZ08 16 +Abnormal palmar dermatoglyphics 0.2715953232498106 0.5190412438925993 0.6037319802454371 1.0 0.9653534557979356 63 O96028,Q8IY17,P25054,Q9UHX1,P51812,O75381,P56589,P40855,Q8NCH0,P98175,P61978 11 +Abnormal epidermal morphology 0.3391572831858956 0.5187044628480462 0.6039668490605439 1.0 0.9653534557979356 20 O75844,Q9Y3Z3,P98194,Q06136,P31749 5 +Aplasia hypoplasia of the 5th finger 0.3537692061377958 0.5161054969424171 0.6057807289237778 1.0 0.9656358395021324 16 Q969G3,Q9UHX1 2 +Waddling gait 0.3154904633818037 0.5158348635869967 0.6059697504690038 1.0 0.9656358395021324 28 Q4J6C6,Q8WVQ1,P02545,Q8TD16,O00189,P09651,Q5T8D3,P06753,Q9H9S5,O75190,P22626 11 +Myoclonus 0.2675216987022121 0.5157579284752652 0.6060234899555044 1.0 0.9656358395021324 95 O75845,O95630,P00374,Q14108,Q969G3,P00846,P13073,Q9NQZ5,O95394,O75503,P27544,Q96JM3,P37198,P50897,P31749,P05067,Q01105,Q10713 18 +Abnormal pelvis bone morphology 0.5185718399078693 0.5152166707115917 0.6064016209506367 1.0 0.9656358395021324 4 Q96DX4,O95613,P16435 3 +Neoplasm of the adrenal cortex 0.4310907575413324 0.5141002604220367 0.6071818953559005 1.0 0.9661877720709384 7 P48735 1 +Microretrognathia 0.3501004610370293 0.5125942625200562 0.6082351674603954 1.0 0.9662347989395608 17 Q16625,Q9UHX1,Q8NCH0 3 +Pace of progression 0.2521340312288134 0.512576933349286 0.6082472919568076 1.0 0.9662347989395608 171 Q13126,Q9NR77,Q9P0J0,Q13501,Q13148,O95831,P55263,O14979,Q10713,Q9Y2Z9,P20700,O00400,P41440,Q8N183,Q9NQZ5,P27544,Q9Y5Y0,Q05682,P31749,Q9H0B6,Q16637,Q9NR28,Q14108,Q15043,Q8N1F7,Q8IY17,Q99720 27 +Recurrent fever 0.3556255689850806 0.5122499820432953 0.6084760662999773 1.0 0.9662691090306756 15 Q9NR77,P61978,P28070 3 +Neoplasm of the oral cavity 0.3551837867977793 0.509602921787559 0.6103296765033581 1.0 0.9677662801537004 15 Q969G3,P31749,P25054,P02545 4 +Periorbital edema 0.3146617036292766 0.5090741018431472 0.610700284089341 1.0 0.9677662801537004 28 Q15056,P28070,Q14C86,Q8NFH4,Q8N1F7 5 +Abnormal urinary color 0.4797657850127076 0.5081188792168083 0.6113699760550408 1.0 0.9678986993620876 5 P23786 1 +Skin dimple 0.3123961156167541 0.5076365194660062 0.6117082746653897 1.0 0.968105664417841 29 O96028,P53701,P49366,P61978 4 +Progressive spastic paraplegia 0.3123438864650854 0.5072031792738404 0.6120122645031749 1.0 0.9682582095124858 29 O75489,Q8IY17,O00400,Q8N183,P00846,Q9P0J0,Q9H0B6 7 +Ankyloglossia 0.429239345994486 0.5057495199055102 0.6130325000359118 1.0 0.9690126113842342 7 O75844 1 +Abnormal lactate dehydrogenase level 0.341347988500594 0.5040724360706712 0.6142104757687901 1.0 0.9697622406857268 19 P23786,Q9UJS0,Q5JRX3,P41440 4 +Oculogyric crisis 0.359314566509973 0.5026283967912423 0.6152255604142354 1.0 0.971036214474448 12 Q96JM3,Q01105 2 +Osteolytic defects of the distal phalanges of the hand 0.5145796635413049 0.5004952405069486 0.6167264066151779 1.0 0.97172478389121 4 O75844,P02545 2 +Synostosis involving digits 0.4479071992575701 0.5002817679178972 0.6168766900015594 1.0 0.97172478389121 6 O94761,Q15233 2 +Abnormality of somatosensory evoked potentials 0.4773749030696193 0.4985885187771451 0.6180692951064195 1.0 0.9722344662314808 5 P20700 1 +Neoplasm of the small intestine 0.44727141302418 0.4975609517677375 0.6187935320098372 1.0 0.9725060830962212 6 Q14191,P25054,P02545 3 +Bilateral ptosis 0.3552390839443903 0.4974560230218509 0.618867507424868 1.0 0.9725060830962212 14 O95169,O60313,Q5T8D3,O00330 4 +Fractures of the long bones 0.5129590316461701 0.4945556873065667 0.6209137883713371 1.0 0.9734134847373308 4 Q13126 1 +Germ cell neoplasia 0.3730478150330376 0.4940243856800638 0.6212889576047216 1.0 0.9734134847373308 11 P31749 1 +Skull asymmetry 0.6120863309352484 0.4939248091646633 0.6213592827586529 1.0 0.9734134847373308 2 Q96DX4 1 +Abnormality of adrenal physiology 0.2945553123086245 0.493593853846405 0.6215930422755385 1.0 0.9734134847373308 38 Q13423,Q969G3,O75381,P04150,P56589,P40855,P31749 7 +Vertebral fusion 0.3729401153192052 0.4934515246302027 0.6216935836292401 1.0 0.9734134847373308 11 O96028,Q9H9S5,Q9UHX1 3 +Sensory neuropathy 0.2951650535842257 0.4910562069494051 0.6233866941760682 1.0 0.9734134847373308 37 O95831,P00846,P22626 3 +Panniculitis 0.3950686427766341 0.4908087258444794 0.6235617378551437 1.0 0.9734134847373308 9 P28070 1 +Abnormal delivery 0.3185941431710394 0.4906499172158473 0.6236740745871936 1.0 0.9734134847373308 24 P33991,P02545,O75718,Q9Y619,O75844,P06753 6 +Incoordination 0.2637381726218716 0.4865564940061836 0.6265726609590394 1.0 0.9752078168251422 74 Q9Y619,P00846,O00165,Q15067,O75503,O43681,Q9NR77,Q01105,Q13501,Q6Y7W6,Q6DKK2,P06753,P37198,Q10713 14 +Upper extremity joint dislocation 0.3190105428463436 0.4859358622990043 0.6270126407534635 1.0 0.9752078168251422 23 Q04721,P25054,Q9Y619,Q8WVQ1,Q96PU5 5 +Abnormality of the nasal tip 0.2644907159688561 0.4849526278028819 0.6277099494474605 1.0 0.9752078168251422 100 Q9UHX1,P42892,Q03164,O95831,Q8WYQ5,Q00577,O60828,P25054,P02545,P16278,Q02252,P21964,P38159,O75845,P51812,O75431,P23786,Q9BZI7,Q9UPP1,O75844,Q969G3,Q96DF8,Q9Y4W2,Q7LGA3,P61978 25 +Deep set nails 0.6176224174277336 0.4822019106107572 0.6296625197196803 1.0 0.9752078168251422 3 Q96L73 1 +Lens subluxation 0.6174438687391948 0.4816335287139596 0.6300663036217831 1.0 0.9752078168251422 3 Q99496,O75533 2 +Optic neuropathy 0.3158686059141257 0.4793406051085606 0.631696339873701 1.0 0.9752078168251422 25 O43676,Q8N183,P00846,Q9P0J0,O96000 5 +Osteolysis involving bones of the upper limbs 0.3923732615666222 0.4776164014176183 0.6329232550449626 1.0 0.9752078168251422 9 O75844,Q04721,P02545 3 +Renal duplication 0.3993196666946561 0.4748728516588171 0.6348776028750571 1.0 0.976928122668844 8 Q9BXW9 1 +Limb tremor 0.4712012481866123 0.4742129047878032 0.6353480918353509 1.0 0.9770252966533844 5 P20700 1 +Abnormality of metacarpophalangeal joint 0.5069375790842101 0.4726791240061134 0.6364421225656249 1.0 0.9777118768210212 4 Q15233 1 +Shawl scrotum 0.4412918869774037 0.4721565662683119 0.6368150391681862 1.0 0.9777118768210212 6 Q9Y619 1 +Abnormality of long bone morphology 0.2540501691346202 0.4707620615401879 0.6378106597465796 1.0 0.9782140470430934 185 P37268,Q96AY3,Q13126,Q9UHX1,O75718,Q32P28,O15228,P38398,Q9NR77,O94761,Q13501,O95831,P98175,P22626,P25054,P02545,Q9Y619,Q08J23,O00116,Q9BXW9,P00813,Q96HY6,Q15056,Q04721,P51812,Q8WVQ1,O75381,P48735,Q9Y2U8,Q15051,O96028,O75312,Q8N0X7,O95453,P56589,Q15427,P40855,O75844,Q96L58 39 +Decreased fertility 0.3078490356089739 0.4701413075175514 0.6382540636700593 1.0 0.9785723053771062 29 P57076,Q8IY17,P02545,P04150,P38398,Q9BXW9,P57740,Q14191 8 +Mental deterioration 0.2629395195856548 0.4693925535842824 0.6387890699832381 1.0 0.9790707270462776 102 Q8IY17,Q9BQE5,O95169,Q14108,P00846,Q9NQZ5,P35637,Q10713,O75503,O43681,Q6Y7W6,Q13148,Q13501,P05067,P50897,P22626,P20700 17 +Bifid scrotum 0.4206114122648113 0.467281617052757 0.640298406848798 1.0 0.9800957563317342 7 P35453,Q96EK5,Q01082,Q69YQ0,O60566 5 +Progressive 0.2582834621697726 0.4647043965689235 0.6421431594478526 1.0 0.9820785444174038 113 Q13126,Q13501,O95831,P55263,Q12768,P20700,O00400,Q8N183,P27544,Q05682,P31749,Q9H0B6,Q16637,Q9NR28,Q96D71,Q15043,Q8N1F7,Q8IY17,Q99720,Q03252 20 +Increased muscle lipid content 0.3896938248186261 0.4645894857059938 0.6422254632232165 1.0 0.9820785444174038 9 P23786 1 +Dyslexia 0.3817779914422581 0.463587406879884 0.6429433784681828 1.0 0.9825320829539989 10 P25054,Q13501 2 +Neurofibrillary tangles 0.5040532324209093 0.4623103790052155 0.6438587576989532 1.0 0.9835099384481056 4 P05067 1 +Acute coronary syndrome 0.3347137242617681 0.4605958819978806 0.6450885666125892 1.0 0.9848422503047842 19 Q15056,Q9NZ08,P02545,O75844 4 +Prominent nasal bridge 0.2724105914134242 0.4592991248266482 0.6460193761543718 1.0 0.9852287992257772 58 Q08J23,P42892,P49366,P38398,P31939,P78318,Q9Y2U8,P21964,Q69YQ0,Q15427,P13073,O95721,Q15233,Q10713,P20700 15 +Arthropathy 0.4673380175298849 0.4591378528565542 0.6461351756293536 1.0 0.9852287992257772 5 Q9Y3Z3 1 +Frontal balding 0.5030142431313571 0.4585934022759589 0.6465261754036367 1.0 0.9854242098309024 4 P04150,O60828 2 +Intellectual disability moderate 0.2636935909601265 0.4551797858502619 0.6489799018020364 1.0 0.9855922756143244 86 P00367,Q4J6C6,P51812,Q9UHX1,P25054,Q08J23,Q969G3,Q96JM3,P38159,P31749,Q01105,P61978,Q10713 13 +Rib fusion 0.3656691429217474 0.455145309133076 0.649004703358381 1.0 0.9855922756143244 11 O96028,O95155 2 +Nonketotic hypoglycemia 0.4174989716968437 0.4535956783458291 0.6501198645890394 1.0 0.9855922756143244 7 P23786 1 +Severe global developmental delay 0.2598380955730043 0.4531948976346424 0.6504084062327888 1.0 0.9855922756143244 70 P51812,O75381,P00846,Q15067,P56589,P55263 6 +Limb girdle muscular dystrophy 0.3946901542827691 0.4531237007033302 0.6504596698707878 1.0 0.9855922756143244 8 O14979,P02545,P09651 3 +Tall chin 0.6082471183772198 0.4526837290294853 0.6507764975732282 1.0 0.9855922756143244 3 Q96L73 1 +Deformed sella turcica 0.4653739469055986 0.4515283502212477 0.651608796954416 1.0 0.9855922756143244 5 Q04721,O75431 2 +Recurrent sinusitis 0.4165771595080489 0.4495626973271098 0.6530257904016863 1.0 0.9855922756143244 7 Q13432 1 +Abnormality of the radial head 0.3644979696233175 0.4490457517064375 0.6533986527014346 1.0 0.9855922756143244 11 Q04721,Q96L58 2 +Widened subarachnoid space 0.3049891699229493 0.4468121368020899 0.6550107074683043 1.0 0.9857570374896452 29 O95831,Q01105 2 +Abnormal talus morphology 0.3188403499482828 0.4452876667260432 0.6561118795825545 1.0 0.9864738531726218 22 Q9UHX1,P02545,O75844,Q99567,P98175,Q14191 6 +Abnormal mitral valve physiology 0.2850420402587903 0.4450139346066691 0.6563096840468794 1.0 0.9864738531726218 42 Q15056,Q04721,P51812,P02545,O75844,O95169,P22681,O95235,P53701,Q96L58,Q9NZ08 11 +Proportionate short stature 0.2913307756195818 0.4429714249288872 0.6577864035031185 1.0 0.9867994346419892 35 Q8IY17,Q8WVQ1,Q9Y619,Q15392,P53701,Q96L58 6 +Breech presentation 0.3764930430376678 0.4373649624781794 0.6618466899050996 1.0 0.9895303644127936 10 O75718,Q9Y619 2 +Nemaline bodies 0.6032472152436561 0.4372225099896543 0.6619499864854022 1.0 0.9895303644127936 3 O43676 1 +Telecanthus 0.2839394032339841 0.434125421449053 0.6641973660759355 1.0 0.9900898198478164 42 Q04721,P51812,P02545,O75844,Q08J23,Q16134,Q03164,P21964,Q86XL3,Q8NCH0,Q69YQ0,Q00577 12 +Pseudobulbar paralysis 0.3905277140325814 0.4337954126612318 0.6644370130995365 1.0 0.9900898198478164 8 P42356,P20700 2 +Abnormal skin morphology of the palm 0.2619311779269214 0.4336335488677184 0.6645545685007148 1.0 0.9900898198478164 95 Q9UHX1,P98175,P25054,P02545,Q8NCH0,Q06136,P31749,P51812,Q99567,O75381,Q9Y2U8,O95721,Q69YQ0,O96028,Q8IY17,P56589,O95453,P57740,P40855,P61978 20 +Dysphagia 0.2380902592428606 0.4311665966622001 0.6663472400512997 1.0 0.9900898198478164 141 Q9UHX1,P00846,Q9NR77,Q96JM3,Q13501,Q13148,P06753,P20700,Q8N183,Q15067,O95155,Q9HD42,P37198,Q01105,Q14108,Q96D71,P35637,P48735,Q6Y7W6,P43243,O95169,Q99720,P05067 23 +Amblyopia 0.3368248657725656 0.4306329508025143 0.6667352782422404 1.0 0.9900898198478164 17 P53701,Q9UHX1 2 +Abnormal coronary artery morphology 0.4115607365725183 0.42778441794305 0.6688080824904328 1.0 0.9900898198478164 7 P34913,P02545 2 +Pleural effusion 0.3452996450900665 0.4254205401881568 0.6705301351851256 1.0 0.9900898198478164 12 P14174,Q9NZ08 2 +Bilateral tonic clonic seizure with focal onset 0.5989614374354093 0.4241315512376228 0.6714698765342475 1.0 0.9900898198478164 3 Q86YH6 1 +Kinetic tremor 0.2879991592118915 0.4241266928993422 0.6714734194935998 1.0 0.9900898198478164 37 Q8IY17,P41440,O43681,P31749,P20700 5 +Unilateral renal agenesis 0.3085228630243722 0.4237670609848291 0.6717357025305577 1.0 0.9900898198478164 25 Q9Y2W2,Q9UHX1,Q8NG31,O43379,Q86XL3,Q15427,Q15058 7 +Abnormal morphology of the limbic system 0.3447237890091291 0.4223169510728436 0.672793687007144 1.0 0.9900898198478164 12 Q01105 1 +Paranoia 0.4099168291149481 0.4207113594708682 0.6739658652401155 1.0 0.9902825433870456 7 Q8WYQ5,P36551 2 +Distal lower limb muscle weakness 0.328381316287914 0.419884111736616 0.6745701150702756 1.0 0.9902825433870456 19 Q9NR77,P00846,Q8IY17,P06753 4 +Adipose tissue loss 0.3802883205698055 0.4195953421759281 0.674781091607116 1.0 0.9902825433870456 9 Q03252,O75844,P02545 3 +Cutis laxa 0.294666333461798 0.4187193934271133 0.6754212206303358 1.0 0.990617790257826 32 Q15056,P51812,Q96L73,O75787,Q8NCH0,O96000,Q96L58 7 +Thick upper lip vermilion 0.3724944480839345 0.4177844486185244 0.6761047220832674 1.0 0.9909969905079696 10 O75845,P25054,Q08J23 3 +Phimosis 0.4908662804663168 0.4158743077869108 0.6775019806211591 1.0 0.9927330309824336 4 Q96L73 1 +Neoplasm of the tongue 0.3791334521371582 0.4141537103146734 0.6787615398350102 1.0 0.9942662756879672 9 P31749 1 +Spastic tetraparesis 0.3043499273573586 0.4131131880687035 0.6795236874981023 1.0 0.994430611083706 27 P00846,Q9H9P8,P37198,P20700 4 +Abnormality of the fontanelles or cranial sutures 0.2510753900509825 0.413076664168456 0.6795504459875605 1.0 0.994430611083706 120 Q96AY3,O75718,Q32P28,O15228,Q16134,O94761,Q96MG7,Q96L73,O95831,P98175,Q12768,P02545,Q9Y619,Q08J23,P21964,O95155,Q8NCH0,P31749,O75845,Q04721,P51812,O75381,Q9Y2U8,Q69YQ0,O15047,P56589,P40855,O75844,Q96L58,P61978 30 +Aspiration 0.3712736307207466 0.4118527768542708 0.6804473352650628 1.0 0.9945071057623776 10 P42356,P43243,P06865 3 +Metatarsal synostosis 0.5867625899280542 0.411769213196036 0.6805085889012981 1.0 0.9945071057623776 2 P35453 1 +Abnormality of pulmonary circulation 0.2962594246708476 0.411310292674132 0.6808450233060188 1.0 0.9945071057623776 31 P02545,O75844,Q14108,O95235,Q69YQ0,O96000,P31749,Q9NZ08 8 +Abnormality of lower limb epiphysis morphology 0.326461745444768 0.4077075368500722 0.6834884035163893 1.0 0.9957839323400606 19 O95831,Q6NUQ1,Q8WVQ1,Q96L58 4 +Abnormal upper limb bone morphology 0.2582029499807805 0.4065017638786949 0.6843739612101105 1.0 0.9957839323400606 104 Q96AY3,Q9UHX1,Q32P28,O15228,P38398,O94761,Q96L73,P98175,O60828,P25054,P02545,O00116,Q08J23,Q9BXW9,P16278,P22681,P31749,Q15056,Q04721,P51812,Q8WVQ1,Q15233,O96028,Q15427,O75844,Q96L58 26 +Ovarian neoplasm 0.3132733396228265 0.4063319475681891 0.6844987145669084 1.0 0.9957839323400606 22 Q01844,P02545,P48735,P31749,Q14191 5 +Enchondroma 0.37741084588094 0.4060723584590947 0.6846894349860897 1.0 0.9957839323400606 9 Q9Y3Z3 1 +Abnormal duodenum morphology 0.3346822676691696 0.4020214977818026 0.687668205054617 1.0 0.995815397031842 16 Q9Y2W2,Q7LBC6,P98175,P38398,Q9BXW9,Q8NCH0,O60566,P49454 8 +Micromelia 0.3066400455484244 0.4019581645393869 0.6877148153330008 1.0 0.995815397031842 24 P25054,Q9UHX1,O75718,Q15392,P48735 5 +Abnormal aortic valve cusp morphology 0.3028278037739726 0.4014068766104832 0.6881205873399903 1.0 0.995815397031842 27 P37268,Q9UHX1,P22681,Q96L58,P61978 5 +Bicornuate uterus 0.3833905698477301 0.4011854234096429 0.6882836118617781 1.0 0.995815397031842 8 Q69YQ0,Q15427,Q9BXW9 3 +Venous thrombosis 0.3382066642891644 0.4005023535417354 0.6887865503483539 1.0 0.995815397031842 14 P31749,Q9NZ08 2 +Hyperesthesia 0.5827338129496368 0.3992854245654466 0.6896829055509515 1.0 0.9963392895776872 2 P07602 1 +Arachnodactyly 0.2867667873111271 0.3979918523786925 0.6906361915990789 1.0 0.9963392895776872 34 O96028,Q9UPP1,Q969G3,P55795,P21964,P57740,Q8NCH0,Q96L58,O60828 9 +Preaxial polydactyly 0.3167428988379543 0.3977808397296866 0.6907917420237055 1.0 0.9963392895776872 21 Q9UPP1,O96028,Q9UHX1 3 +Neck muscle weakness 0.3339117061048378 0.3975576587649436 0.6909562766715416 1.0 0.9963392895776872 16 Q99720,P06753,P35637 3 +Minimal change glomerulonephritis 0.3337436452907255 0.3965856969372739 0.6916730016448631 1.0 0.9965903242729816 16 Q8N1F7,Q14C86,Q8NFH4 3 +Weakness of muscles of respiration 0.2890584167069394 0.3933462534857647 0.6940637603331146 1.0 0.9982513166702928 33 P36551,Q15067,Q13148,O95831,P43243,P06753,P22626 7 +Proximal upper limb amyotrophy 0.4028602025783162 0.3907251292212189 0.6960004220914677 1.0 0.9982513166702928 7 O14979 1 +Abnormality of the musculature of the upper arm 0.4028602025783162 0.3907251292212189 0.6960004220914677 1.0 0.9982513166702928 7 O14979 1 +Cerebral edema 0.3810321123162629 0.390564820352512 0.6961189335061124 1.0 0.9982513166702928 8 P23786 1 +Limitation of joint mobility 0.2571206273053381 0.3901996946672094 0.6963888873853483 1.0 0.9982513166702928 104 P37268,Q96AY3,Q8TD16,O94761,Q96L73,P06753,O14979,P25054,P02545,P16278,O95155,P31749,P54802,Q15056,O75431,P48735,P23786,O15460,Q9Y2U8,O75844,Q96L58,Q15427,Q7LGA3,Q14191 24 +Premature graying of hair 0.3528875928681259 0.3897362429884263 0.6967315934954719 1.0 0.9982513166702928 11 O95453,Q13126,Q14191,P02545 4 +Positive romberg sign 0.3737715416626528 0.3891420129121559 0.6971710961670756 1.0 0.9982513166702928 9 Q9Y5Y0 1 +Malar prominence 0.5872193436960145 0.3890651864094021 0.6972279257780625 1.0 0.9982513166702928 3 O60934,Q9Y4W2 2 +Optic disc hypoplasia 0.4485528779401545 0.3879764997779411 0.6980334245726332 1.0 0.9986588626401108 5 O95721 1 +Micropenis 0.2581514432098874 0.3842582175199904 0.7007870727786722 1.0 1.0 65 Q8IY17,Q9Y619,P48449,P42892,Q9BXW9,Q9Y3Z3,P53701,Q9H9S5,Q10713 9 +Tube feeding 0.2550855533366829 0.3802238997881341 0.703779219673371 1.0 1.0 72 P37268,Q9UHX1,Q99720,P35637,Q96JM3,Q01105,P61978 7 +Abnormality of the biliary system 0.2463490538837458 0.3794577157169367 0.7043479984410408 1.0 1.0 124 P22830,Q16134,P38398,Q96L73,P55263,Q10713,P00374,P02545,O43681,P21964,O15118,Q9Y3Z3,P21266,Q00059,O75845,Q6NUQ1,Q15056,Q9UJS0,Q04721,Q14108,O75381,Q5XKP0,Q16625,P11166,P09601,Q69YQ0,O96028,P36551,P56589,O75787,P14174,P40855 32 +Focal emotional seizure 0.3645168053075051 0.3794354177141639 0.7043645539002918 1.0 1.0 10 Q01105 1 +Generalized clonic seizure 0.5829015544041316 0.3764774810964881 0.7065619536572603 1.0 1.0 3 P07602,O14936 2 +Abnormality of hair pigmentation 0.3031128510300221 0.3764737723934286 0.7065647103286521 1.0 1.0 24 P37268 1 +Emotional lability 0.2667079452034622 0.3745552504583301 0.7079912589929647 1.0 1.0 56 Q969G3,Q8N183,P35637,P43243,O43681,Q9P0J0,Q13501,Q13148,Q15165,Q92804,P31749 11 +Abscess 0.3702147137503696 0.3727891797993009 0.7093053565813996 1.0 1.0 9 O95394,Q13546 2 +Prenatal maternal abnormality 0.3308581443811651 0.3689662544406079 0.7121528779250541 1.0 1.0 15 O43772,P57076,P49366 3 +Abnormality of chorioretinal pigmentation 0.476942061377048 0.3687105955975947 0.7123434502277666 1.0 1.0 4 Q9Y619 1 +Axonal degeneration regeneration 0.4763305106315604 0.3666863032422651 0.7138530244064327 1.0 1.0 4 P02545 1 +Bilateral polymicrogyria 0.3612223757780977 0.3638943696776297 0.71593688919418 1.0 1.0 10 Q96JM3,Q01105 2 +Blue irides 0.3608306893567956 0.3620586418077237 0.7173082089695184 1.0 1.0 10 Q15056,P28482,O43709,O95714,Q9Y4P3,P35250,Q9UIG0,P78347,P10644 9 +Neoplasm of the pituitary gland 0.3249458511861577 0.3601780070495006 0.7187140203826023 1.0 1.0 17 Q969G3,P31749,P48735 3 +Paraplegia 0.266011533158276 0.3592563859968663 0.7194032982765308 1.0 1.0 55 O75489,Q8IY17,O00400,Q9Y619,Q8N183,P00846,P56589,P49902,Q9P0J0,O95831,Q96L58,Q9H0B6 12 +Aplasia hypoplasia involving the nose 0.2875581906831125 0.3588643986375414 0.7196965337798495 1.0 1.0 32 P02545,Q08J23,Q8NB90,P55795,O75431,O94761,Q8WYQ5,O75844,Q00577,P61978 10 +Median cleft palate 0.5692086330935218 0.3586536979547221 0.7198541705053181 1.0 1.0 2 Q14739 1 +Periauricular skin pits 0.3464961162182222 0.358059700421087 0.7202986367178841 1.0 1.0 11 O96028,Q69YQ0,P61978 3 +Pneumothorax 0.4130889618412697 0.3574380662579151 0.7207638836303223 1.0 1.0 6 Q8NCH0 1 +Metaphyseal widening 0.310574706024869 0.357041840895339 0.7210604827899143 1.0 1.0 21 O95831,Q96HY6,Q96L58,Q8WVQ1 4 +Impaired pain sensation 0.3059016424256162 0.3559353317991406 0.7218889952920824 1.0 1.0 22 O95831,Q9NR77,P61978 3 +Progressive pes cavus 0.4396711540014952 0.3556884212875799 0.7220739171911983 1.0 1.0 5 O00400 1 +Infectious encephalitis 0.359248013120747 0.3546675524185805 0.7228386620683336 1.0 1.0 10 Q9NZ08 1 +Severe failure to thrive 0.4725916842218853 0.354400458287641 0.7230387911588438 1.0 1.0 4 O75844 1 +Bradycardia 0.3308485731250585 0.3538327714755043 0.7234642121417678 1.0 1.0 13 O43772 1 +Hereditary nonpolyposis colorectal carcinoma 0.3656763153514961 0.3522138678142738 0.7246778774818345 1.0 1.0 9 P31749 1 +Abnormal growth hormone level 0.2866864928503028 0.3516382471807235 0.725109577731843 1.0 1.0 32 Q4J6C6,Q8IY17,Q969G3,P31749,Q12768 5 +Hypoplastic fingernail 0.3234281906884803 0.3513999646418578 0.7252883089159048 1.0 1.0 17 Q969G3,P51812,Q12768 3 +Shallow orbits 0.3584746684088508 0.351071634371968 0.7255346077009195 1.0 1.0 10 O75844,P02545,P61978 3 +Pierre robin sequence 0.3932218217661263 0.3508158557929346 0.7257265011055085 1.0 1.0 7 Q8WYQ5 1 +Excessive salivation 0.2840479562730182 0.3505546667596353 0.7259224713784982 1.0 1.0 33 Q9NW08,P51812,P55795,Q8N0X7,O00189,P42356,Q9NR77,Q03252,O75787,Q9BZI7,Q15233 11 +Hypercholesterolemia 0.3302018717351027 0.350443593571045 0.7260058150906685 1.0 1.0 13 Q15904,Q9UJS0,P02545,O75431,Q8N511,P57740 6 +Skin erosion 0.371072416136176 0.3466270180925822 0.7288715454241776 1.0 1.0 8 P98194,O75844 2 +Nephritis 0.2987969180951431 0.345768141114377 0.7295169697273165 1.0 1.0 24 O95394,Q14C86,Q03252,Q8NFH4,Q8N1F7 5 +Male sexual dysfunction 0.3266109166825261 0.3455967334575544 0.729645801201676 1.0 1.0 15 P31749,P20700 2 +Abnormality of the ankles 0.2706789731054341 0.344913767007618 0.7301592004339597 1.0 1.0 45 Q96AY3,Q15056,P02545,O75844,Q15043,Q8N0X7,P49902,O75787,Q9HD42,P06753,Q15233 11 +Abnormalities of placenta or umbilical cord 0.3194001087091982 0.3441411515355258 0.7307401363877739 1.0 1.0 18 O75844,P02545,Q12768 3 +Shyness 0.469416785056978 0.3440912884977637 0.7307776341277141 1.0 1.0 4 Q15233,O00189 2 +Abnormal large intestine physiology 0.3084666738586507 0.3433466010043746 0.7313377266166488 1.0 1.0 21 O43681,P20700 2 +Abnormal circulating sex hormone concentration 0.2988070680168877 0.3408857971409806 0.7331895573734675 1.0 1.0 23 Q969G3,Q13423,P31749 3 +Hyperglycemia 0.3629903880083451 0.3401962512195118 0.7337087411051133 1.0 1.0 9 P35610,O75844,P02545 3 +Chromosomal breakage induced by crosslinking agents 0.5698864513901194 0.3395882785125231 0.73416660650262 1.0 1.0 3 P13073 1 +Multicystic kidney dysplasia 0.3033965483790716 0.3391446928460057 0.7345007313699947 1.0 1.0 22 O75381,P56589,P40855 3 +Lower limb spasticity 0.255145645817559 0.3382657952214708 0.7351628974631614 1.0 1.0 85 Q8IY17,Q9Y619,O00400,Q99720,P00846,Q8N183,P35637,P56589,P49902,Q6DKK2,O95831 11 +Leiomyosarcoma 0.3625405574985297 0.3381954709188975 0.7352158886759694 1.0 1.0 9 P31749 1 +Abnormal thoracic spine morphology 0.2928259335351147 0.3371130414613703 0.7360316866122867 1.0 1.0 28 O75845,Q9UPP1,Q9UHX1,O75844,O95831,P06753 6 +Abnormal proportion of cd8 positive t cells 0.4671441842572317 0.3367831101602053 0.7362804061967227 1.0 1.0 4 O95394 1 +Polydactyly 0.2633059237955152 0.3365878919390437 0.7364275849855655 1.0 1.0 56 O75845,O96028,Q8IY17,Q9UHX1,Q9UPP1,Q15067,Q9BXW9,O95155,P61978,P98175,Q12768,Q10713 12 +Abnormality of the ribs 0.24991744228772 0.3353438030044006 0.7373657546639296 1.0 1.0 68 Q9UHX1,O75718,Q32P28,Q03164,O94761,O95831,Q12768,P25054,P02545,Q9Y619,P16278,O95155,P00813,Q96HY6,P54802,O96028,Q15427,O75844,Q96L58 19 +Lower limb amyotrophy 0.3027646896530384 0.3349379990974733 0.7376718568490617 1.0 1.0 22 Q15120,P02545,O00400,Q8TD16,Q9NR77,P06753,Q9NVI7,Q9H0B6 8 +Aplasia hypoplasia of the abdominal wall musculature 0.4337322056149626 0.3346311989725361 0.7379033070548764 1.0 1.0 5 Q8WVQ1 1 +Focal non motor seizure 0.3416057594905923 0.3343334827861719 0.7381279270500019 1.0 1.0 11 Q96JM3,Q01105 2 +Progressive spasticity 0.3224126245329466 0.3324605230748821 0.7395415440240551 1.0 1.0 16 P51812 1 +Focal segmental glomerulosclerosis 0.2946568035866321 0.3303412385681371 0.7411421363168857 1.0 1.0 26 Q14108,Q14C86,P57740,Q9Y2Z9,Q8NFH4,Q8N1F7 6 +Palmar telangiectasia 0.5588489208633058 0.3289294216561421 0.7422090353199982 1.0 1.0 2 Q14739 1 +Abnormality of the pulmonary veins 0.3669458028383687 0.3288797929504243 0.7422465483724405 1.0 1.0 8 Q15392,O75718 2 +Low frustration tolerance 0.3601225254818807 0.327499986757816 0.7432897529746818 1.0 1.0 9 Q9UHX1,Q6Y7W6 2 +Muscle abnormality related to mitochondrial dysfunction 0.2764857882539062 0.325992444121691 0.7444300718631391 1.0 1.0 38 P00846,O43676,Q9Y2R0 3 +Hypopigmented skin patches 0.2937065120355789 0.3234716824794177 0.7463380498752379 1.0 1.0 26 O95453,Q9BXW9,P21964,P53701,P31749 5 +Schizophrenia 0.3087744562435072 0.320276283732705 0.7487588998769779 1.0 1.0 20 O15047,Q9BQE5,O43681,P21964,Q6Y7W6 5 +Narrow pelvis bone 0.5618883131836354 0.3177393226069481 0.7506826805968974 1.0 1.0 3 Q96DX4,P16435 2 +Abnormality of the forearm 0.2627670662366093 0.3175236097987948 0.7508463276023938 1.0 1.0 54 O96028,Q96AY3,Q15056,P25054,Q8WVQ1,Q04721,Q32P28,P38398,Q9BXW9,P22681,Q15427,P98175,Q96L58 13 +Abnormal lung development 0.2635556604918737 0.3162549880606973 0.751808973385536 1.0 1.0 52 O96028,P57076,Q9UHX1,P02545,O75844,Q99567,Q16134,P21964,O96000,Q8WYQ5,P98175,P31749,Q96L58 13 +Recurrent pneumonia 0.3081104086060048 0.3161888257709735 0.7518591887557293 1.0 1.0 20 P20700,O95394,P00813,Q13432,P78318 5 +Hypoplasia of the radius 0.3505639829245797 0.314898344723427 0.7528388384380109 1.0 1.0 10 P98175,P25054,Q15427 3 +Hypoplasia of the uterus 0.35013583047367 0.3129732461808722 0.754300988245661 1.0 1.0 10 P57740,P53701 2 +Pigmentary retinopathy 0.2637035327377274 0.3113045371503378 0.7555691183930751 1.0 1.0 50 Q8IY17,Q8N183,P00846,Q15067,P53701 5 +Natal tooth 0.35640182445619 0.3112430478889197 0.7556158595699856 1.0 1.0 9 O75844,P02545 2 +Abnormal mitochondrial morphology 0.3367159990071356 0.311080296476398 0.7557395796770732 1.0 1.0 11 P35637,Q13501 2 +Spastic paraplegia 0.2628013622137829 0.3083114126663746 0.7578453827036524 1.0 1.0 52 Q8IY17,O00400,Q9Y619,Q8N183,P00846,P56589,P49902,Q9P0J0,O95831,Q9H0B6 10 +Absent facial hair 0.3490629109832791 0.3081643204472932 0.7579573003260229 1.0 1.0 10 O75844,P02545 2 +Branchial anomaly 0.3620056131391885 0.3080088390532969 0.7580756065105361 1.0 1.0 8 P61978 1 +Tented upper lip vermilion 0.2939620332735152 0.30778187282155 0.7582483158595146 1.0 1.0 23 Q02252,Q4J6C6 2 +Vertebral hypoplasia 0.3357269900273997 0.3064364770832 0.759272338622053 1.0 1.0 11 P16278,Q04721,Q96HY6 3 +Disproportionate short trunk short stature 0.4254637517526375 0.3060685741179271 0.7595524346663225 1.0 1.0 5 Q96DX4,Q9UHX1,P16278 3 +Skeletal muscle atrophy 0.2414639340759824 0.3047020042270892 0.760593123007081 1.0 1.0 172 Q13126,Q9NR77,Q9BQT8,Q13501,Q13148,O95831,P55263,P06753,O14979,P22626,O00400,Q9Y5Y0,Q9H9S5,Q9HCC0,Q9H0B6,Q16637,P51812,Q99567,P35637,Q9Y2U8,Q92804,P43243,Q8IY17,Q99720,Q9NWM8,Q6DKK2,Q15165 27 +Retinal coloboma 0.3547565871437854 0.304133969235041 0.761025828136833 1.0 1.0 9 Q9UHX1 1 +Late onset 0.3546773753271924 0.3037929459891024 0.7612856412029729 1.0 1.0 9 P31751,P18031,O00330 3 +Hiatus hernia 0.354481313936775 0.3029493586019079 0.761928454994955 1.0 1.0 9 Q69YQ0,Q8NCH0 2 +Delayed ability to roll over 0.4561882532633249 0.3024140551170191 0.762336441613513 1.0 1.0 4 P82663,P51970 2 +Psychomotor deterioration 0.3541111070505242 0.3013584167417342 0.7631411998567903 1.0 1.0 9 P06865,P50897 2 +Syringomyelia 0.3972327114405697 0.2972924330954682 0.7662432581550951 1.0 1.0 6 Q9Y2U8,Q04721 2 +Abnormality of the spinal cord 0.2513428813765011 0.2937302890520785 0.7689640074148452 1.0 1.0 82 Q9UHX1,P38398,O94761,Q10713,Q12768,P20700,Q9Y2W2,P25054,O00400,Q08J23,Q9BXW9,P21964,Q9Y5Y0,P31749,Q9H9S5,O75845,Q15056,Q04721,Q9Y2U8,O96028,Q8IY17,Q96L58,P05067 23 +Irregular menstruation 0.3788187443805318 0.2936683654176271 0.7690113296807783 1.0 1.0 7 Q06787,P04150,P02545 3 +Hand muscle weakness 0.3329124649466859 0.2933337832981795 0.7692670334316705 1.0 1.0 11 Q8TD16,Q9NR77,Q13501 3 +Caesarian section 0.4530214413409574 0.2927550012492808 0.7697094257589285 1.0 1.0 4 P33991 1 +Abnormality of the achilles tendon 0.3175044871682207 0.2903461062184805 0.7715514695521131 1.0 1.0 14 O60313,P02545,Q08J23,Q8TD16,Q92734,Q9H9S5 6 +Female hypogonadism 0.3778121042530952 0.2897944617080236 0.7719734850705664 1.0 1.0 7 O75844 1 +Viral hepatitis 0.4206023486415158 0.2897041858692918 0.7720425537366027 1.0 1.0 5 P25054 1 +Subacute progressive viral hepatitis 0.4206023486415158 0.2897041858692918 0.7720425537366027 1.0 1.0 5 P25054 1 +Megalocornea 0.3173071410380304 0.2893435252167133 0.7723185077149248 1.0 1.0 14 O96028,Q9H9S5 2 +Leukocytosis 0.2828833943650337 0.2875636315001336 0.773680787277647 1.0 1.0 30 Q6UN15,P35610,O95394,P22681,Q03252,Q01130,P00813 7 +Increased intracranial pressure 0.3032233130593512 0.2864966692491367 0.7744977441635694 1.0 1.0 20 Q969G3,P31749,Q9NZ08 3 +Nocturnal hypoventilation 0.5497507797755553 0.2858405159906669 0.7750002748906879 1.0 1.0 3 P61978 1 +Large earlobe 0.3564813021514774 0.2851768267297147 0.7755086731366689 1.0 1.0 8 Q15392 1 +Spina bifida 0.2717232269052785 0.2838512698449396 0.776524362055246 1.0 1.0 38 O75845,Q15056,Q9UHX1,Q08J23,P38398,Q9BXW9,P21964,O94761,Q9H9S5,Q10713 10 +Distal arthrogryposis 0.3935182231270406 0.2837220287066194 0.7766234116977886 1.0 1.0 6 Q8NCH0 1 +Papillary thyroid carcinoma 0.3306628461557727 0.2829833550453305 0.7771895964718445 1.0 1.0 11 Q969G3 1 +Paraparesis 0.2821967783517521 0.2823288622242835 0.7776913565180164 1.0 1.0 30 Q9Y619,P35637,Q8N0X7,P42356,O75787,Q9Y3Z3,Q13501,Q13148,Q6DKK2 9 +Severe lactic acidosis 0.5476537550025082 0.280488020926818 0.7791031146868252 1.0 1.0 3 Q70HW3 1 +Abnormal lung lobation 0.3161951409977309 0.2793395850602783 0.7799842303536171 1.0 1.0 13 P31749,Q9UHX1 2 +Abnormal cerebral artery morphology 0.3139631719192853 0.2784991096295205 0.780629248428691 1.0 1.0 15 P05067 1 +Polyphagia 0.3422446930500264 0.2781273689369778 0.7809145868904075 1.0 1.0 10 Q4J6C6 1 +Abnormality of neuronal migration 0.2371316925880113 0.2767222932896093 0.7819933525134437 1.0 1.0 163 P37268,Q16134,Q86XL3,Q96JM3,Q10713,P20700,Q08J23,P31749,Q01105,P51812,O75381,Q15392,Q16625,O60508,P23786,O95721,Q15051,P56589,P40855,P61978 20 +Paraplegia paraparesis 0.2502133323067287 0.2764384249288322 0.782211347247991 1.0 1.0 83 Q13148,Q8IY17,O75489,Q9Y619,O00400,Q8N183,P00846,P35637,P56589,P49902,P42356,Q9P0J0,Q9Y3Z3,Q6DKK2,Q13501,O95831,Q96L58,Q9H0B6 18 +Radial bowing 0.4163793994029762 0.2757570544389661 0.7827346707611078 1.0 1.0 5 Q96L58 1 +Narrow nasal bridge 0.4162264490044349 0.2752566773753134 0.7831190457319297 1.0 1.0 5 Q15233 1 +Abnormal larynx morphology 0.2812541106156215 0.2751719726900382 0.7831841186267936 1.0 1.0 30 P25054,Q9UHX1,P02545,P21964,Q15427,P43243,Q69YQ0,Q96HY6 8 +Lymphedema 0.3141942029122825 0.2736586876993591 0.784346928581668 1.0 1.0 14 P22681,P31749 2 +Urticaria 0.3148896304946511 0.2729502001155591 0.784891496953624 1.0 1.0 13 P22681,Q01130 2 +Abnormality of the thymus 0.3113521125816834 0.2728158186426477 0.784994799150875 1.0 1.0 16 P00813 1 +Weak cry 0.3527893817397341 0.2702291158922438 0.7869839943996175 1.0 1.0 8 Q69YQ0,P06753 2 +Prominent antihelix 0.5433111962652 0.2695564680605297 0.7875014943771501 1.0 1.0 3 P98175 1 +Typical absence seizure 0.3120204110183929 0.268548817927316 0.7882769030762868 1.0 1.0 15 Q01105,P61978 2 +Pulmonary fibrosis 0.2965756025531225 0.2684974406713506 0.7883164446214459 1.0 1.0 21 P09601,P14174,P21266,O95453 4 +Shoulder girdle muscle weakness 0.3103753056450448 0.2677020998243469 0.7889286333657135 1.0 1.0 16 Q9H9S5,Q8TD16,P46976,P43243,P06753,O14979 6 +Aplasia hypoplasia involving bones of the thorax 0.2698049235588903 0.2671617223135625 0.7893446464497929 1.0 1.0 38 Q9UHX1,P02545,Q9Y619,O75844,Q03164,Q96L58,O95155,Q15427,P98175,Q96HY6,Q12768 11 +Orthostatic hypotension 0.3116019858534053 0.2664188833535724 0.7899166237876334 1.0 1.0 15 O43681,P20700 2 +Skin appendage neoplasm 0.3883607029674417 0.2652282854996133 0.7908336062633998 1.0 1.0 6 P43246,Q9UPY3,P25054,Q15437,Q92793 5 +Long nose 0.3391687444575905 0.2648828288661729 0.791099726582938 1.0 1.0 10 Q8NB90,Q04721 2 +Nonprogressive 0.3709286212758004 0.2637518556653487 0.7919711348056013 1.0 1.0 7 Q10713 1 +Abnormal retinal artery morphology 0.2916056511983594 0.2626719822311025 0.7928034135946902 1.0 1.0 22 P06865,P21964,P00846,Q15056 4 +Frequent falls 0.267682150812865 0.2615234841552923 0.7936888417612473 1.0 1.0 40 P00846,O43681,Q9NR77,Q6Y7W6,P06753,P37198 6 +Tracheoesophageal fistula 0.2952371985253006 0.2603474924292744 0.7945957416083544 1.0 1.0 21 Q15056,O95453,P38398,Q9BXW9,Q69YQ0 5 +Childhood onset 0.268797625383133 0.2584668404308524 0.7960466371711541 1.0 1.0 38 O15047,P22830,O00165,Q5JRX3,O75431,Q8N0X7,Q9NR77,Q14566,Q9Y5Y0,Q9BZI7 10 +Dysgammaglobulinemia 0.5317985611510752 0.257487439799855 0.7968025101095686 1.0 1.0 2 O60934 1 +Abnormality of the maxilla 0.2700062319334901 0.2570625568507503 0.7971304817508273 1.0 1.0 35 O95630,P51812,Q9Y619,O95453,Q15427,P31749,O60828 7 +Asthma 0.3013373102970844 0.2567036619873944 0.7974075444031421 1.0 1.0 19 O95394,P00813,Q08J23 3 +Muscle weakness 0.2658953015032331 0.2542069861954107 0.7993356536485341 1.0 1.0 303 Q13126,Q9UHX1,O43676,P00846,Q16134,Q9NR77,Q9BQT8,Q9P0J0,Q13501,Q13148,O95831,P13073,O14979,P22626,P20700,Q10713,Q4J6C6,P00374,P41440,O00400,Q8N183,Q15067,O43681,Q9Y5Y0,Q8NCH0,P31749,P37198,Q16637,P51812,Q6UN15,O75381,Q15043,P35637,P23786,O15460,Q92804,O95721,P51114,O43772,Q8IY17,P36551,Q70HW3,O95169,Q99720,Q969G3,P56589,Q5T8D3,Q9NWM8,Q6DKK2,P40855,Q15165,P61978 52 +Aplasia hypoplasia of the nasal bone 0.5297841726618666 0.2525425397356021 0.8006217374211084 1.0 1.0 2 P10644 1 +Upper eyelid coloboma 0.5297841726618665 0.2525425397356021 0.8006217374211084 1.0 1.0 2 Q13428 1 +Congenital craniofacial dysostosis 0.5297841726618666 0.2525425397356021 0.8006217374211084 1.0 1.0 2 P10644 1 +Constitutional symptom 0.2593891361071687 0.2520566462121392 0.8009972795309148 1.0 1.0 258 P28070,P00846,P42892,P04150,Q14C86,Q9NR77,Q13501,Q13148,P06753,P22626,Q12768,P20700,Q13423,Q4J6C6,P25054,P02545,P35610,O43681,P21964,P22681,Q07021,Q9Y5Y0,Q8NFH4,P31749,Q96HY6,Q9H9S5,Q15056,Q9UJS0,P51812,Q6UN15,Q04721,Q01844,Q14108,Q15043,P35637,Q3ZCQ8,P23786,P48735,O15460,Q9Y2U8,Q01130,Q92804,P43243,Q8N1F7,P36551,Q70HW3,Q13546,P0DP25,Q969G3,Q99720,Q14566,Q03252,P14174,Q15165,O75844,Q9NZ08 56 +Abnormal dermatoglyphics 0.2464621557149954 0.2510603571253355 0.8017674448808727 1.0 1.0 76 O96028,Q8IY17,P25054,Q9UHX1,P51812,O75381,P56589,P22681,P40855,Q8NCH0,P98175,P61978 12 +Severe combined immunodeficiency 0.3667164196493432 0.2482130063760599 0.8039696035542816 1.0 1.0 7 P00813 1 +Skin rash 0.2892254785500893 0.2477892442561684 0.8042974773027414 1.0 1.0 22 P28070,P22681,P14174,Q01130,Q06136 5 +Pili torti 0.5343733024864606 0.2477169510893988 0.8043534155000029 1.0 1.0 3 P02545 1 +Abnormal pulmonary interstitial morphology 0.2690602556180408 0.2473699462388543 0.8046219309680815 1.0 1.0 34 P57076,Q14108,O95453,P57740,P14174,P09601,Q13432,P21266 8 +Spontaneous abortion 0.5340212411765228 0.246875177476297 0.8050048273328763 1.0 1.0 3 Q14191 1 +X linked dominant inheritance 0.283570761651079 0.2464158474936737 0.8053603398657505 1.0 1.0 25 P53701,P51812 2 +Abnormal spermatogenesis 0.3041531851362543 0.2450023284529286 0.8064546284527303 1.0 1.0 17 Q13423,P04150,Q9BXW9 3 +Iron deficiency anemia 0.3824814503745853 0.244658979615205 0.8067204923645368 1.0 1.0 6 P25054 1 +Abnormality of the tarsal bones 0.2771468225374794 0.2444074264033076 0.8069152907195087 1.0 1.0 30 Q9UHX1,P02545,Q8WVQ1,Q99567,O75844,O75787,P98175,Q14191 8 +Episodic pain 0.3089228726621435 0.2443042334159987 0.8069952050074387 1.0 1.0 13 P23786 1 +Abnormal consumption behavior 0.2786215997830863 0.2433693846107482 0.8077192584671136 1.0 1.0 29 Q4J6C6,Q9UJS0,Q969G3,P49366,O95155 5 +Scleroderma 0.3819723263129837 0.242904129560988 0.8080796664396603 1.0 1.0 6 Q9Y2U8,P02545 2 +Hyperinsulinemic hypoglycemia 0.339937801846526 0.24244032377101 0.8084389922916966 1.0 1.0 9 Q9UKG1,O00330,P00367,P53985 4 +Limb girdle muscle atrophy 0.3078394560039035 0.2424242996736655 0.8084514074181908 1.0 1.0 14 P06753,Q9H9S5,O14979 3 +Redundant skin 0.2821322431423385 0.2423275401021515 0.8085263756809757 1.0 1.0 26 O96000,Q15056,P51812,Q8NCH0 4 +Loss of eyelashes 0.5315249393054542 0.2409472617496791 0.8095959913962525 1.0 1.0 3 O75844 1 +Foam cells 0.381218370131048 0.2403132420268912 0.8100874301077525 1.0 1.0 6 O75845,O15118 2 +Abnormality of complement system 0.4346419360236952 0.2392874353870905 0.8108827075617808 1.0 1.0 4 Q03252 1 +Central hypothyroidism 0.3076904730024603 0.2369820889519258 0.8126706854651855 1.0 1.0 12 P31749 1 +Phonophobia 0.3634005763688698 0.2362008057463532 0.8132768543106539 1.0 1.0 7 Q15056,Q9Y4P3,P35250,Q92793,Q9UIG0,P78347 6 +Flat cornea 0.3634005763688698 0.2362008057463532 0.8132768543106539 1.0 1.0 7 Q15056,Q9Y4P3,P27448,P35250,Q9UIG0,P78347 6 +Hypokalemia 0.3323328881884531 0.2361656583477297 0.8133041265141194 1.0 1.0 10 P0DP25 1 +Abnormal peripheral myelination 0.2661284323246124 0.2356639941852894 0.8136934114784367 1.0 1.0 38 O43681,Q9Y5Y0,P00846,P20700 4 +Respiratory insufficiency 0.2414922987091565 0.234438966398746 0.8146442105839391 1.0 1.0 185 Q96AY3,O43676,Q9NR77,Q13501,Q13148,O95831,P06753,P33991,Q9Y619,Q08J23,Q8N183,Q15067,Q9H9S5,Q9HCC0,Q16637,Q8WVQ1,Q99567,O75381,P35637,P23786,Q92804,P53701,P43243,O96000,O43772,P57076,P36551,Q70HW3,O95169,P56589,P40855,Q15165 32 +2 3 toe syndactyly 0.2673663571874797 0.2336535053391588 0.8152539859794092 1.0 1.0 34 P37268 1 +Abnormal cd4 cd8 ratio 0.3792193547717175 0.2334895388392511 0.8153812918927423 1.0 1.0 6 Q13432 1 +Mild postnatal growth retardation 0.520863309352514 0.2312940418676798 0.8170863751092612 1.0 1.0 2 P10644 1 +Hypodontia 0.2558096365938566 0.2296623282253785 0.8183541701742607 1.0 1.0 47 O96028,Q15056,P25054,P02545,P51812,Q15067,O95453,Q9Y2U8,Q96L73,O75844 10 +Postural instability 0.2990021605090112 0.2293529848148198 0.8185945748812284 1.0 1.0 18 Q9NR77,P41440,O75503 3 +Gonosomal inheritance 0.2438686244574377 0.2274687768643283 0.8200592453615854 1.0 1.0 74 P51812,P53701,Q9UPP1,P55795,Q969E8,P38159,O95831,P98175 8 +Transient ischemic attack 0.3608605181855402 0.2271332636071886 0.8203201192843865 1.0 1.0 7 O75844 1 +Aplasia hypoplasia of the phalanges of the hallux 0.51827338129496 0.2253261571303823 0.8217255523848308 1.0 1.0 2 P35453 1 +Aplasia hypoplasia of the distal phalanges of the toes 0.51827338129496 0.2253261571303823 0.8217255523848308 1.0 1.0 2 P35453 1 +Hyporeflexia of lower limbs 0.317356891817936 0.2241223529584959 0.8226620997143412 1.0 1.0 11 Q9NR77,P02545,Q9H0B6 3 +Pectus carinatum 0.2656448688386587 0.223789698186392 0.8229209463443272 1.0 1.0 36 Q96AY3,P51812,P55795 3 +Functional motor deficit 0.2298255521843357 0.2222131287016223 0.8241479743722495 1.0 1.0 150 P00846,Q9NR77,Q13501,Q9Y2R0,P06753,P20700,Q15067,O43681,Q07021,Q9Y3Z3,P31749,Q9H9S5,P37198,Q9H0B6,P35637,P23786,Q6Y7W6,P53701,Q969G3,Q99720,Q9NWM8,P61978 22 +Narrow nasal ridge 0.3594634373143596 0.2221964162228028 0.8241609838329891 1.0 1.0 7 O75844,P02545 2 +Urinary urgency 0.3168842176764713 0.2221093073323898 0.8242287926106124 1.0 1.0 11 Q9UBB4,Q12768,P20700 3 +Abnormality of subcutaneous fat tissue 0.3008352716735484 0.2191796645587649 0.8265100956948737 1.0 1.0 16 O75844 1 +Calcific stippling 0.5220004844913254 0.2189936092485933 0.8266550260278558 1.0 1.0 3 O15228 1 +Fasting hyperinsulinemia 0.3740953108938833 0.2163066702187113 0.8287487100572022 1.0 1.0 6 P00367 1 +Regional abnormality of skin 0.2261742155494719 0.2152609271815123 0.8295638911042045 1.0 1.0 137 Q96AY3,Q9UHX1,P98175,P25054,P02545,P22681,Q8NCH0,Q06136,P31749,Q15056,P51812,Q99567,O75381,Q9Y2U8,O95721,Q69YQ0,O96028,Q8IY17,P55795,P56589,O95453,P57740,P40855,P61978 24 +Stroke 0.2639338182334217 0.213017748719807 0.8313131189078578 1.0 1.0 37 Q15056,P02545,O75844,P04150,P05067,O95721,Q96L58 7 +Abnormal metaphyseal trabeculation 0.3957628970142854 0.2114731147294229 0.8325181091554605 1.0 1.0 5 Q04721 1 +Abnormal c peptide level 0.3952761498846956 0.2100354608216902 0.8336399965428984 1.0 1.0 5 Q9UKG1,O00330 2 +Hemiparesis 0.2928832748064267 0.2099959630517074 0.8336708238090136 1.0 1.0 19 Q969G3,O43379,P11166,P31749,Q9NZ08 5 +Long palpebral fissure 0.2829887720408248 0.209760035189727 0.8338549663886021 1.0 1.0 22 P51812,P20700 2 +Stillbirth 0.3137470882744999 0.2088908133302716 0.8345334758662006 1.0 1.0 11 O75844 1 +Abnormality of the adrenal glands 0.2457132642084243 0.2078542312430727 0.8353427867912337 1.0 1.0 63 P33991,Q13423,P25054,Q969G3,O75381,P04150,P48735,P56589,P40855,O75844,P31749,Q12768 12 +Abnormality of the palm 0.2381680959844116 0.2058663119429884 0.836895340947766 1.0 1.0 120 O96028,Q8IY17,P51812,Q9Y619,Q9UHX1,O75381,O95721,P98175,P56589,P40855,O95831,Q06136,P31749,P61978 14 +Type ii transferrin isoform profile 0.4222248802617085 0.2058120953512017 0.8369376927400722 1.0 1.0 4 O75787 1 +Hypoplastic vertebral bodies 0.3708468768776981 0.2056480896232107 0.8370658102084527 1.0 1.0 6 P16278 1 +Pedal edema 0.3358777991539163 0.2051804350233566 0.8374311548450604 1.0 1.0 8 Q14108,Q96L73 2 +Cardiac arrest 0.2637112641980635 0.2045294552281213 0.8379397765161551 1.0 1.0 34 O15460,O43772,P31749 3 +Pyridoxine responsive sideroblastic anemia 0.4215891220572267 0.2041582709454578 0.8382298194885622 1.0 1.0 4 Q9BXW9 1 +Clubbing of toes 0.4215891220572267 0.2041582709454578 0.8382298194885622 1.0 1.0 4 Q9BXW9 1 +Dilated cardiomyopathy 0.2593401432163988 0.2040728622252164 0.8382965608766095 1.0 1.0 42 P00846,P53701,P23786 3 +Submucous cleft of soft and hard palate 0.2776261205743803 0.2040727246605125 0.8382966683754622 1.0 1.0 24 Q9Y2W2,P02545,Q9Y619,Q08J23,Q15392,Q96DF8,Q8WYQ5,O75844,Q9H9S5 9 +Protruding ear 0.2545234134762296 0.2035040085386954 0.8387411128754387 1.0 1.0 46 P25054,P51812,Q08J23,Q8NCH0,Q06136,P61978,P20700 7 +Chronic fatigue 0.3345629117618089 0.2003715487347858 0.8411900090883928 1.0 1.0 8 Q13423 1 +Lung adenocarcinoma 0.5132790259095847 0.1998316482683042 0.8416122487672026 1.0 1.0 3 P30154 1 +Muscle hypertrophy of the lower extremities 0.3232512711956983 0.199627054546103 0.8417722671831918 1.0 1.0 10 Q9NR77,Q9H9S5 2 +Abnormal circulating ceruloplasmin concentration 0.4198070279956367 0.1995542521872207 0.8418292095011379 1.0 1.0 4 O00400 1 +Ketoacidosis 0.3285541822052004 0.1981413159936001 0.842934500107805 1.0 1.0 9 Q9HCC0,P53985 2 +Abnormal sternum morphology 0.2385507800044649 0.1952729894227649 0.8451792413371033 1.0 1.0 118 Q96AY3,Q9UHX1,O75718,Q03164,P42356,Q96L73,O95831,P98175,P06753,O60828,P07437,Q9Y2W2,P02545,Q9Y619,Q08J23,P16278,P22681,Q8NCH0,P31749,Q15056,Q04721,P51812,O75431,Q69YQ0,O96028,P55795,P57740,Q96L58,P61978,P78318 30 +Exaggerated startle response 0.3326809083934166 0.1935539602062052 0.8465251507820422 1.0 1.0 8 P06865,Q00577,Q9H0B6 3 +Diabetes insipidus 0.2965368375832093 0.1930223539396354 0.8469414613732178 1.0 1.0 15 P31749 1 +Psychosis 0.264453412182055 0.1927082122278277 0.8471874915824806 1.0 1.0 33 Q9UJS0,P51812,P36551,Q5JRX3,O15118,Q13501,Q6DKK2 7 +Abnormally low pitched voice 0.3323724416258384 0.1924439331978912 0.8473944817617978 1.0 1.0 8 O75530,Q9UQE7,O60885,Q15022,Q96L73,Q6KC79,O60216 7 +Paresthesia 0.2754484212300239 0.1904594453855215 0.8489491193658645 1.0 1.0 24 O15460,P05067,Q9NZ08 3 +Dysphasia 0.2891671622944747 0.1902210131790244 0.8491359456015755 1.0 1.0 19 P53701,Q9H9P8,Q13501 3 +Non motor seizure 0.2516762860116523 0.190041474490192 0.8492766307526523 1.0 1.0 48 P51812,P00374,Q96JM3,Q01105,P61978 5 +Ventricular hypertrophy 0.2613886876585897 0.1893784265177835 0.8497962316652692 1.0 1.0 36 O43772,O95630,P02545,P23786,Q07021,O75844,Q9H9S5,Q15233 8 +Axial muscle weakness 0.3879821975634327 0.1889559738042953 0.8501273229245496 1.0 1.0 5 Q9H9S5,P02545 2 +Gastrointestinal hemorrhage 0.2673220447179517 0.1852183833075762 0.8530577507593291 1.0 1.0 31 Q9UJS0,P25054,Q9UHX1,P22681,P21964,Q01130,Q9NZ08 7 +Bird like facies 0.3485761212270221 0.1849914260195977 0.8532357605537313 1.0 1.0 7 O75844 1 +Foot dorsiflexor weakness 0.2609877540793028 0.184289626332367 0.8537862515404129 1.0 1.0 35 P02545,Q99720,Q9NR77,Q9BQT8,Q13501,P06753,Q6UWE0 7 +Abnormal morphology of the abdominal musculature 0.3075517105058223 0.1835302864601274 0.8543819571818123 1.0 1.0 11 Q8WVQ1,P09651,P22681,Q8NCH0,Q69YQ0 5 +Epiphyseal dysplasia 0.3860015488923434 0.1833842726789384 0.8544965151959927 1.0 1.0 5 Q8WVQ1 1 +Urethral atresia 0.4987050359712188 0.1832214841027237 0.8546242378252973 1.0 1.0 2 Q9UPM9 1 +True hermaphroditism 0.4987050359712188 0.1832214841027237 0.8546242378252973 1.0 1.0 2 Q9UPM9 1 +Lobar holoprosencephaly 0.4987050359712188 0.1832214841027237 0.8546242378252973 1.0 1.0 2 Q9UPM9 1 +Abnormality of the testis size 0.2652197561779242 0.1832047251460891 0.854637386986455 1.0 1.0 32 O75312,Q9UPP1,P38398,Q9BXW9,P38159,P31749,Q14191,O60828 8 +Peripheral axonal neuropathy 0.2453906347571464 0.18314440173815 0.8546847173680647 1.0 1.0 61 O95831,P00846,Q8IY17,P22626 4 +Abnormality of carpal bone ossification 0.363615711119048 0.182595595288238 0.8551153406905154 1.0 1.0 6 Q8WVQ1 1 +Severe expressive language delay 0.412977904740697 0.1823502148089836 0.8553078934991862 1.0 1.0 4 Q96DX4,Q8NB90 2 +Supravalvular aortic stenosis 0.3632958801498179 0.1815979041944281 0.8558982937129349 1.0 1.0 6 Q15056,Q9Y4P3,P35250,Q9UIG0,P78347 5 +Nystagmus induced head nodding 0.3632958801498179 0.1815979041944281 0.8558982937129349 1.0 1.0 6 Q15056,Q9Y4P3,P35250,Q9UIG0,P78347 5 +Overfriendliness 0.3632958801498179 0.1815979041944281 0.8558982937129349 1.0 1.0 6 Q15056,Q9Y4P3,P35250,Q9UIG0,P78347 5 +Generalized joint laxity 0.29499309081643 0.1812298102807827 0.8561871967886843 1.0 1.0 13 Q9UHX1 1 +Aplasia hypoplasia involving the skeletal musculature 0.3236289417121047 0.1798759415225286 0.8572499630016943 1.0 1.0 9 Q9NR77,P06753 2 +Short femur 0.3841194689549743 0.1781511120771533 0.858604302363166 1.0 1.0 5 Q9UHX1 1 +Prenatal movement abnormality 0.2429366829981842 0.1769557302154585 0.8595431628988401 1.0 1.0 63 P51114,O96028,Q16637,Q4J6C6,Q70HW3,P56589,O75844 7 +Abnormal sacrum morphology 0.2598161263176367 0.1769077363676112 0.8595808617288965 1.0 1.0 36 O96028,P53701,P49366,P61978 4 +Abnormality of the auditory canal 0.2808382721368734 0.1766273160394538 0.8598011363211229 1.0 1.0 21 O96028,Q9H9S5,Q9Y619 3 +Talipes equinovarus 0.2426562116970431 0.1747429472459358 0.8612816199023843 1.0 1.0 85 Q96AY3,P42356,Q9NR77,O94761,P06753,P98175,Q9Y619,P49902,P21964,Q8NCH0,Q9HD42,O75845,Q8WVQ1,Q15392,O96028,Q9NWM8,Q15427,Q96L58,P61978 19 +Dyspnea 0.2417639135567296 0.1747139232633765 0.8613044268704755 1.0 1.0 106 Q6UN15,Q9Y619,O75844,Q9UHX1,O95169,P00846,P35637,P23786,O95831,Q92804,P53701,Q15165 12 +Impaired temperature sensation 0.3608339340844378 0.1739812519538715 0.8618801962905593 1.0 1.0 6 Q9NR77 1 +Myeloid leukemia 0.382389350490692 0.1733935391079172 0.8623421032337402 1.0 1.0 5 Q01130 1 +Prostate neoplasm 0.3444935011110879 0.1716385767746512 0.8637216776007377 1.0 1.0 7 P25054 1 +Thyroid carcinoma 0.2799111664976372 0.1715016830703818 0.863829307150416 1.0 1.0 21 Q969G3,P31749,P25054 3 +Pancreatic fibrosis 0.4988485895221508 0.1701522912362694 0.8648903705810098 1.0 1.0 3 Q9Y3E5,Q9UPM9 2 +Abnormality of skeletal muscle fiber size 0.2796400893447184 0.1700093990443579 0.8650027448899069 1.0 1.0 21 O95831,P06753,P22626,Q13501 4 +Corneal ulceration 0.3801245727602605 0.1672431217567173 0.8671787559386988 1.0 1.0 5 O75844 1 +Abnormal cry 0.303422545527249 0.1671948547987553 0.8672167327133176 1.0 1.0 11 Q69YQ0,P06753 2 +Breast carcinoma 0.2718170517750786 0.1670401845134399 0.867338430422145 1.0 1.0 23 Q14191,P31749,P25054,P48735 4 +Weak voice 0.3575640177695744 0.1640396948618165 0.8696998950681571 1.0 1.0 6 P43243,O75787 2 +Oral pharyngeal dysphagia 0.2900757063501423 0.1636462020759898 0.8700096709640377 1.0 1.0 15 Q01105 1 +Large for gestational age 0.3023414460044651 0.1629948342676841 0.8705225019386535 1.0 1.0 11 P31751,Q9UKG1,O00330 3 +Abnormal atrioventricular valve physiology 0.2476788357842252 0.1618714674408508 0.8714070721430716 1.0 1.0 54 Q15056,Q04721,P51812,P02545,O75844,O95169,Q96L58,P22681,O95235,P53701,Q9UER7,Q15233,Q9NZ08 13 +Thick hair 0.3560933448573924 0.1596341474665497 0.8731692781216847 1.0 1.0 6 Q9UQE7,P38606,Q9Y487,P36543,Q9BUK6 5 +Absent hair 0.3013750310250997 0.1592677472580916 0.8734579303327017 1.0 1.0 11 O75844,P02545 2 +Joint swelling 0.3226394445065818 0.1585160382182973 0.8740501837668668 1.0 1.0 8 Q13510,P35670,P14174 3 +Chronic constipation 0.2675356490901651 0.1581360825715332 0.8743495685354803 1.0 1.0 28 O15047,P55795,P78318,Q03252,Q6Y7W6,Q9BZI7,P20700 7 +Generalized hyperpigmentation 0.2893280003792529 0.157215813011649 0.8750747662937526 1.0 1.0 13 Q13423 1 +Abnormality of chromosome segregation 0.3543647363872122 0.1545086020275748 0.8772087292274136 1.0 1.0 6 P51608,Q15437,Q14739,Q7Z5J4,O60566 5 +Radioulnar synostosis 0.2694859177223595 0.153372385153536 0.8781046206704961 1.0 1.0 23 O96028,Q15056,P25054,Q8WVQ1,P22681,Q96L58 6 +Wide intermamillary distance 0.269294793352015 0.1522624622591517 0.8789799304365931 1.0 1.0 23 P07437,P23786,P61978 3 +Synostosis of joints 0.2541104540783705 0.1521571205008206 0.8790630129824921 1.0 1.0 41 O96028,Q15056,P25054,Q9UHX1,Q8WVQ1,Q96L58,P22681,O94761,Q15427,Q9H9S5,O60828,Q15233 12 +Melena 0.4001505391928802 0.1519591758283902 0.8792191346096945 1.0 1.0 4 P25054 1 +Saccadic smooth pursuit 0.399760932008931 0.1510761036665944 0.8799156826319008 1.0 1.0 4 Q06787,Q10713 2 +Poor wound healing 0.3738479262672861 0.1506620090727595 0.8802423434370903 1.0 1.0 5 O15269,O15270,P04062,O00170 4 +Status epilepticus 0.2474177520643734 0.1502941602663109 0.8805325400928785 1.0 1.0 49 P42892,Q15392,Q96JM3,P53701,Q01105 5 +Broad chin 0.4811510791366862 0.1500127921677156 0.8807545227776754 1.0 1.0 2 Q9H5V9 1 +Aplasia hypoplasia of the distal phalanges of the hand 0.2562329703051089 0.1490089444425557 0.8815465751188851 1.0 1.0 36 O95630,P51812,Q04721,Q969G3,O75844 5 +Muscle fiber inclusion bodies 0.3090257067740141 0.1463803813192086 0.8836211139210939 1.0 1.0 10 O43676 1 +Attenuation of retinal blood vessels 0.31860035710772 0.1450773448246322 0.8846498052430771 1.0 1.0 8 Q9Y5Y0 1 +Generalized osteosclerosis 0.4854463411554415 0.1448958037988828 0.8847931395565236 1.0 1.0 3 Q15392 1 +Peritoneal abscess 0.3964871868701409 0.1437502362979202 0.8856977002949704 1.0 1.0 4 P04637,P42771,P38398 3 +Functional intestinal obstruction 0.3964871868701409 0.1437502362979202 0.8856977002949704 1.0 1.0 4 P04637,P42771,P38398 3 +Extrahepatic cholestasis 0.3964871868701409 0.1437502362979202 0.8856977002949704 1.0 1.0 4 P04637,P42771,P38398 3 +Ovarian carcinoma 0.3964871868701409 0.1437502362979202 0.8856977002949704 1.0 1.0 4 P04637,P42771,P38398 3 +Fulminant hepatic failure 0.3956233803627942 0.1418454272279296 0.8872021010758984 1.0 1.0 4 P40939,Q16836,P98170 3 +Cloverleaf skull 0.4756834532374056 0.140556096770968 0.8882206335189129 1.0 1.0 2 P16435 1 +Irregular vertebral endplates 0.3343061614956866 0.1398093441128979 0.8888106302778924 1.0 1.0 7 O15228 1 +Abnormal peripheral nervous system physiology 0.2426871243926017 0.1383459744265472 0.8899669924778284 1.0 1.0 59 Q9Y619,Q99720,O43681,Q9Y5Y0,O95831,O95721,P20700 7 +Myotonia 0.3163559907437037 0.1377770664296939 0.8904166098202184 1.0 1.0 8 O75190,P50402,Q00577,P02545 4 +Entropion 0.3063176240808232 0.1368274192531882 0.8911672100403703 1.0 1.0 10 O75844 1 +Hyperextensible skin 0.2802746815659728 0.1354686462483413 0.8922413523790267 1.0 1.0 18 Q9NWM8,Q9UHX1,Q8NCH0 3 +Abnormality of the plantar skin of foot 0.2510431135395358 0.1335520156759165 0.8937568301000753 1.0 1.0 42 P02545,O95721,O95453,Q9Y2U8,O94761,P42166,Q06136,P31749,P61978 9 +Plantar hyperkeratosis 0.254220014370058 0.1321806626266805 0.8948413958950987 1.0 1.0 34 P02545,O95721,O95453,Q9Y2U8,O94761,P42166,Q06136,P31749 8 +Buphthalmos 0.3909327689843771 0.1317085079239388 0.8952148557978405 1.0 1.0 4 P31749 1 +Decreased adipose tissue 0.2826270976262839 0.1314767624350463 0.8953981678810716 1.0 1.0 15 Q03252,O75844,P02545 3 +Supranuclear gaze palsy 0.2751891275735235 0.1314553181476582 0.8954151307245652 1.0 1.0 20 Q99720,P35637,Q13501,Q13148 4 +Diminished motivation 0.2641053708947058 0.1306634209234558 0.896041570072365 1.0 1.0 27 P35610,P35637,P06865,O43464,Q13501,Q13148,Q6Y7W6,Q9UBB4 8 +Abnormal gastrointestinal motility 0.2608993638791599 0.1301774214529069 0.8964260576301841 1.0 1.0 30 P36551,P35637,P61978,Q9Y5Y0 4 +Abnormal circulating igm level 0.2802906313769707 0.1287785875184436 0.8975328491156567 1.0 1.0 17 O95394,P00813,Q96MG7 3 +Abnormal blood sodium concentration 0.3089159062904554 0.1287756207478038 0.8975351967095082 1.0 1.0 9 Q13423,P36551 2 +Acute lymphoblastic leukemia 0.2819016276266291 0.1284441285986674 0.8977975107777025 1.0 1.0 15 Q08J23,O00165,P35658,Q96L73,O60566 5 +Abnormality of the middle phalanges of the toes 0.4758203799654445 0.1281440132742808 0.8980350055886883 1.0 1.0 3 Q08AM6,P35453 2 +Pulmonary cyst 0.3450351331169802 0.1278452251912265 0.8982714591669394 1.0 1.0 6 P31749 1 +Vitreous hemorrhage 0.3881370572991681 0.1258332537411237 0.8998639183022092 1.0 1.0 4 Q99496,P06400,O75533 3 +11 pairs of ribs 0.3125961138143707 0.1258189590618863 0.8998752338753337 1.0 1.0 8 O95155 1 +Spina bifida occulta 0.273790118239011 0.1244902710051707 0.9009271030711344 1.0 1.0 20 O94761,Q9UHX1,Q15056,Q08J23 4 +Osteolysis 0.2568737263275503 0.1235965563265928 0.9016347192334828 1.0 1.0 32 P25054,Q14108,P48735,P22681,Q13501,Q01130,O75844,P22626 8 +Choriocarcinoma 0.472366148531939 0.1224164946922971 0.9025691758822908 1.0 1.0 3 O95999,P42771 2 +Poikiloderma 0.3423897202158252 0.1205973469977189 0.9040099702955092 1.0 1.0 6 O94761 1 +Azoospermia 0.2796797225595743 0.1182809125883817 0.9058450807722902 1.0 1.0 14 Q13423,Q9BXW9 2 +Duodenal stenosis 0.3605863438986062 0.1179237243438843 0.9061280950935776 1.0 1.0 5 Q9BXW9 1 +Aplasia hypoplasia of the ulna 0.2776672406840487 0.1103890737958298 0.9121008180190406 1.0 1.0 14 Q15427,P25054,P38398,Q9BXW9 4 +Sporadic 0.2578644526512766 0.1103146418582371 0.9121598456112596 1.0 1.0 30 O96028,P51812,Q03252,Q9BWD1,Q69YQ0,P31749 6 +Renal cell carcinoma 0.2618101258996353 0.1101126003194519 0.9123200753156884 1.0 1.0 23 Q92733,P25054,P31749 3 +Melanoma 0.2651938774042882 0.1098058063678697 0.9125633860783652 1.0 1.0 22 O94761,P31749,Q14191,P38398 4 +Dyschromatopsia 0.3236983287582482 0.1090144332842334 0.913191042458741 1.0 1.0 7 Q9H061,O60313 2 +Gray matter heterotopia 0.2509552818403121 0.1084996325981207 0.9135993719392724 1.0 1.0 35 Q15058,Q06787,Q7Z3E5,Q9UEY8,Q8NG31,O43379,Q86XL3,Q96PU5,Q9BSJ2,P31749,Q9H9S5,P61978 12 +Neonatal insulin dependent diabetes mellitus 0.3781498404138289 0.1058675949337252 0.9156874050385346 1.0 1.0 4 Q9UKG1 1 +Difficulty walking 0.2368354022670356 0.1056520639248318 0.9158584148388508 1.0 1.0 84 Q969G3,Q99720,P00846,Q15067,P35637,O43681,Q9NR77,Q9Y3Z3,Q13501,P06753,P31749,Q9H9S5,Q9H0B6 13 +Bilateral cleft palate 0.4523741007194198 0.1049148711900185 0.9164433585903522 1.0 1.0 2 O60716 1 +Bilateral cleft lip and palate 0.4523741007194198 0.1049148711900185 0.9164433585903522 1.0 1.0 2 O60716 1 +Non midline cleft palate 0.4523741007194198 0.1049148711900185 0.9164433585903522 1.0 1.0 2 O60716 1 +Joint hyperflexibility 0.2465688752907743 0.1041168886648202 0.9170765884828402 1.0 1.0 43 Q15056,Q04721,Q8WVQ1,Q9Y619,P02545,Q08J23,P51812,P22681,P21964,Q96L73 10 +Abnormality of cardiovascular system electrophysiology 0.2333105751686158 0.1040215329436909 0.917152260450101 1.0 1.0 116 O43772,P0DP25,O95169,O75381,P00846,P42892,P56589,P23786,O15460,Q01130,P53701,P31749 12 +Abnormality of temperature regulation 0.234782191327008 0.1027211790611641 0.9181842641000068 1.0 1.0 112 O43772,Q8N1F7,Q6UN15,P28070,P00846,P23786,O15460,Q9NR77,P61978,Q9Y3Z3,Q01130,P00813,Q9NZ08,P20700 14 +Missing ribs 0.2747275316271652 0.1021761928231232 0.918616824215264 1.0 1.0 12 O95155,Q96L58 2 +Nonprogressive cerebellar ataxia 0.4585492227979083 0.101000695023617 0.9195499084499072 1.0 1.0 3 Q4G0N4,O75027 2 +Chorea 0.2374527334901091 0.1005740536770474 0.9198885944128165 1.0 1.0 91 O95169,Q99720,P00846,P35637,O43681,Q96JM3,P37198,Q9HD42,Q01105 9 +Variable expressivity 0.2360416450596756 0.0989203363444925 0.9212015220297224 1.0 1.0 83 Q9Y375,Q8TD16,O95470,Q9NR77,O00429,P06753,Q00577,P02545,P00374,Q13868,Q9Y3Z3,O00330,Q15125,Q15058,Q9H9S5,Q9H061,Q8WVQ1,P11166,Q9NQT5,P46976,P43243,Q9BUF5,Q70HW3,Q9NWS8,Q9UEY8,Q5T160,Q13813,O95453,Q9Y263,Q6P4A7,P57740,Q15427 32 +Abnormality of the diencephalon 0.2495748366906981 0.0986590239048546 0.9214090042648596 1.0 1.0 34 Q9UPT5,Q15056,Q96KP1,Q969G3,Q13057,O95169,P49792,Q99496,Q8WWQ0,Q92917,P11166,Q9H269,O00443,P31749,Q9H9S5 15 +Absence of subcutaneous fat 0.3191669127821229 0.096613488026986 0.9230333447101526 1.0 1.0 7 O75844 1 +Cutaneous melanoma 0.3510944700460874 0.0964496535859678 0.923163458046163 1.0 1.0 5 P11802,Q14191,P42771,Q99496 4 +Aplasia hypoplasia of the uterus 0.272668557525131 0.0958761216985536 0.9236189593229494 1.0 1.0 17 O96028,P53701,P57740 3 +Cns demyelination 0.2733502855899781 0.095641713611637 0.9238051343650138 1.0 1.0 16 Q15067,P40855 2 +Occipital encephalocele 0.3185469734501822 0.0949525938414985 0.924352481349228 1.0 1.0 7 Q10713 1 +Aplasia hypoplasia of toe 0.2475476906083019 0.09455408593573 0.9246690204831862 1.0 1.0 40 O96028,Q04721,P25054,Q9UHX1,P02545,Q69YQ0,Q15427,P13073,P00813 9 +Supernumerary nipple 0.283288709422762 0.0944737384111348 0.9247328428362968 1.0 1.0 11 Q8IY17 1 +Finger syndactyly 0.2453411226755 0.0942047277165532 0.9249465293035776 1.0 1.0 43 Q8IY17,P25054,Q9Y619,P38398,Q9BXW9,Q9Y2U8,Q69YQ0,Q15427,P98175,P31749,Q12768 11 +Curly eyelashes 0.3321809276865507 0.0939536868884749 0.9251459464379924 1.0 1.0 6 Q9UQE7,O60885,Q6KC79,Q8N3U4,O60216 5 +Ovoid vertebral bodies 0.3017753719807967 0.0933466812972327 0.9256281476387632 1.0 1.0 8 P16278,Q96L58 2 +Abnormal response to acth stimulation test 0.4434532374100671 0.09323339335359 0.9257181458578982 1.0 1.0 2 P16435 1 +Bilateral cleft lip 0.4525043177892813 0.0923778197327852 0.926397861353856 1.0 1.0 3 Q9NXE4,O60716 2 +Neoplasm of the endocrine system 0.2458004656943537 0.0912985147764805 0.9272553980982376 1.0 1.0 42 P25054,P02545,Q969G3,P42892,P48735,Q9UER7,P31749 7 +Platybasia 0.3472761512064196 0.0882788152531639 0.9296550761881176 1.0 1.0 5 Q04721 1 +Chondrocalcinosis 0.3298015487015876 0.0880506377257336 0.9298364293119046 1.0 1.0 6 Q14191,P02545 2 +Bacterial endocarditis 0.4376978417266146 0.0862532393308929 0.9312651094915164 1.0 1.0 2 P10644 1 +Supranuclear ophthalmoplegia 0.4376978417266139 0.086253239330892 0.9312651094915172 1.0 1.0 2 Q99700 1 +Substantia nigra gliosis 0.4376978417266139 0.086253239330892 0.9312651094915172 1.0 1.0 2 Q99700 1 +Poikilocytosis 0.2703087790969338 0.0825058113558431 0.9342444972987018 1.0 1.0 15 Q05682,P41440 2 +White forelock 0.4444193886494977 0.081545615381926 0.9350080498131504 1.0 1.0 3 P02545 1 +Delayed ability to walk 0.230204083970138 0.0766050109534558 0.9389377725058206 1.0 1.0 72 Q99720,P49366,P35637,P61978,Q9Y5Y0,Q01105,Q10713,P20700 8 +Positional foot deformity 0.2342915054457301 0.0762062740118725 0.9392549912671976 1.0 1.0 107 Q96AY3,Q9UHX1,P42356,Q9NR77,O94761,Q8WYQ5,P98175,P06753,P02545,Q9Y619,P49902,P21964,Q8NCH0,Q9HD42,O75845,Q8WVQ1,Q15392,Q69YQ0,O96028,Q9NWM8,Q15427,Q96L58,P61978 23 +Genetic anticipation 0.4401108478940299 0.0760964407009135 0.9393423718413108 1.0 1.0 3 Q9UBB4 1 +Lissencephaly 0.2374956813798904 0.0760309965112433 0.9393944379127088 1.0 1.0 57 Q9NWS8,Q8NG31,O95721,Q16134,Q15392,Q16625,P23786,P42356,P57740,Q86XL3,Q9H9S5,Q15058,P20700 13 +Duodenal atresia 0.3112396643141732 0.0760290160651379 0.939396013519546 1.0 1.0 7 O60566,Q9Y2W2,P49454 3 +Pollakisuria 0.3610711200691007 0.0754420856506123 0.9398629750903592 1.0 1.0 4 Q8WVX9,Q06787,O60934 3 +Micrographia 0.4378238341968747 0.0732942415160041 0.941571973981512 1.0 1.0 3 Q96RL7,Q99700 2 +Short stepped shuffling gait 0.4378238341968725 0.0732942415160016 0.941571973981514 1.0 1.0 3 Q14203,Q99700 2 +Head banging 0.4372481289579544 0.0725986485968807 0.9421255021477044 1.0 1.0 3 Q96RL7,Q7Z5J4 2 +Subcutaneous hemorrhage 0.2450572713673732 0.072223743007587 0.9424238503245864 1.0 1.0 39 Q13126,Q6UN15,Q14108,Q16625,Q9BXW9,Q9NWM8,Q8NCH0,Q96L58 8 +Interrupted aortic arch 0.4352490843594937 0.070213771408411 0.9440235133795092 1.0 1.0 3 Q8WYQ5 1 +Shoulder girdle muscle atrophy 0.3377227043596998 0.0690177936342642 0.9449754559999286 1.0 1.0 5 P06753 1 +Bell shaped thorax 0.357064644545927 0.068981255051907 0.9450045402540808 1.0 1.0 4 Q8WVQ1 1 +Abnormal rectum morphology 0.2470603068377055 0.0687522609171252 0.9451868183865456 1.0 1.0 33 P53701,P31749,P51812 3 +Broad phalanx of the toes 0.3569012792342179 0.0687232269750468 0.9452099294576356 1.0 1.0 4 Q7LGA3,O14936 2 +Peptic ulcer 0.2657349481198112 0.0684420504324844 0.9454337488835212 1.0 1.0 13 Q01130 1 +Lacrimal duct atresia 0.4210071942446 0.0683812189972635 0.9454821719002696 1.0 1.0 2 Q9NX14 1 +Dysplasia of the femoral head 0.4328076367245744 0.0673649310586133 0.9462911867071062 1.0 1.0 3 Q96L58 1 +Barrel shaped chest 0.3558882810250483 0.0671326873876794 0.9464760718106432 1.0 1.0 4 P04066,Q14739,Q32P28 3 +J shaped sella turcica 0.3558882810250421 0.0671326873876696 0.9464760718106512 1.0 1.0 4 P08236,O60568,O75431 3 +Macrogyria 0.3204672422772544 0.0660296233298289 0.9473542409048856 1.0 1.0 6 Q15392 1 +Long eyelashes 0.241761429247791 0.0659342565961795 0.9474301670924836 1.0 1.0 43 Q4J6C6,Q8IY17,Q9UHX1,Q9Y619,Q969G3 5 +Abnormality of the hepatic vasculature 0.2656084399333698 0.0652729427040258 0.9479566849849916 1.0 1.0 15 P22681,Q10713,Q01130 3 +Somatic mutation 0.2374437723844151 0.0645929454207398 0.9484981017201256 1.0 1.0 47 P25054,P22681,Q92733,Q92804,P00813,P31749 6 +Hypoplasia of the frontal lobes 0.2643933702923828 0.0639675329807928 0.9489960787705912 1.0 1.0 13 Q8NG31,Q86XL3,Q15058 3 +Abnormal tendon morphology 0.2430224376996419 0.0624597858155288 0.950196685651306 1.0 1.0 228 P37268,Q96AY3,P28070,O15228,P42892,Q9NR77,Q86XL3,O95831,P06753,P34913,P20700,Q9Y619,P41440,Q08J23,P49902,O95155,Q9Y3Z3,Q9Y5Y0,Q9HD42,Q8NCH0,Q9H9S5,Q9H0B6,Q8WVQ1,Q99567,Q15043,Q15392,P35637,P23786,P48449,Q99720,O75844,P50897 32 +4 5 toe syndactyly 0.4141007194244561 0.0619707921538766 0.9505860917652982 1.0 1.0 2 P35453 1 +Abnormality of fibula morphology 0.2625245108946903 0.0610741517981411 0.9513001545892208 1.0 1.0 12 Q8WVQ1,Q15427,Q96HY6 3 +Neoplasm of the breast 0.2487847301572992 0.0609019689144809 0.951437281391714 1.0 1.0 31 P25054,P02545,P48735,P38398,P31749,Q14191 6 +Abnormality of the calf musculature 0.2599745605321213 0.0601761063075233 0.952015375624708 1.0 1.0 20 Q9NR77,Q9H9S5,P43243,Q12768 4 +Synostosis involving bones of the hand 0.2637937697774526 0.0598645408507499 0.9522635215233006 1.0 1.0 14 O94761,P25054,Q96L58,Q15233 4 +Hyperphosphatemia 0.4106474820143841 0.0589713361768312 0.9529749387833112 1.0 1.0 2 P10644 1 +Abnormal bleeding 0.2327290747458298 0.058760452918338 0.9531429080038968 1.0 1.0 108 Q13126,Q9UHX1,P11117,P02545,P25054,Q9BXW9,P22681,Q8NCH0,P31749,Q9UJS0,Q6UN15,Q14108,Q16625,P23786,O15460,Q01130,Q969G3,Q96L58,Q9NWM8,O75844,Q96PU5,P05067,Q9NZ08 23 +Abnormal hand bone ossification 0.3035356027296474 0.0573955933012987 0.954230073253678 1.0 1.0 7 Q8WVQ1 1 +Lymphopenia 0.2509994891072612 0.0572213488524099 0.95436887209603 1.0 1.0 28 O95394,P00813,Q13432,P28070 4 +Poor motor coordination 0.2624900622545146 0.0554413353763585 0.9557868655912308 1.0 1.0 17 Q06787,O75503,Q7Z5J4,O00330,Q9H9S5,Q10713 6 +Genu varum 0.2617239553846951 0.0552542230281922 0.9559359311478292 1.0 1.0 13 Q8WVQ1,Q9Y619,Q96HY6 3 +Pointed chin 0.24322083646736 0.0550069692989904 0.9561329115035486 1.0 1.0 34 Q15056,Q04721,Q96EK5,O00429,O95155,Q96JM3,Q96L73,P36543,Q7LGA3,P20700 10 +Eeg with irregular generalized spike and wave complexes 0.4210842455981363 0.0546453482965642 0.9564210099923962 1.0 1.0 3 Q9NQZ5 1 +Skin pit 0.2621275556900685 0.0542632801710853 0.9567254046078484 1.0 1.0 14 O96028,Q69YQ0,P61978 3 +Abnormal muscle fiber protein expression 0.3014416317343851 0.0525665406825256 0.9580772767624628 1.0 1.0 7 P50402,Q9H9S5,P02545 3 +Eyelid coloboma 0.2792821394255045 0.0524484741517638 0.9581713504526396 1.0 1.0 10 Q9Y3Z3 1 +Abnormal insulin level 0.2501405563843474 0.0523892807911687 0.9582185150785868 1.0 1.0 28 P31751,P02545,P53985,O75844,P00367 5 +Limb girdle muscle weakness 0.2491906125295944 0.0510226309141649 0.9593074871708176 1.0 1.0 29 O60313,Q13126,Q9H9S5,P02545,Q8TD16,P46976,P43243,P06753,O14979 9 +Abnormality of the uterus 0.2347611706947177 0.0506230423418936 0.959625901230027 1.0 1.0 57 O96028,P25054,P51812,Q9BXW9,P21964,P57740,Q69YQ0,Q15427,P53701,P31749,Q16740 11 +Aplasia hypoplasia of the uvula 0.3133706930159124 0.0505093146879446 0.9597165268330632 1.0 1.0 6 Q9BXW9 1 +Aplasia hypoplasia of the phalanges of the thumb 0.2589935364255138 0.0501337201726099 0.960015828701866 1.0 1.0 12 Q8WVQ1 1 +Pulmonary carcinoid tumor 0.41562712341748 0.0492531593696245 0.960717547588031 1.0 1.0 3 P02545 1 +Personality changes 0.2586509719722878 0.0477956718297329 0.9618790859955404 1.0 1.0 19 Q8IY17,P20700 2 +Pseudobulbar signs 0.2575738532332855 0.0458570947574105 0.963424151600348 1.0 1.0 12 P42356,Q15233,P20700 3 +Bimanual synkinesia 0.3248847926267281 0.0457930378359991 0.9634752079931964 1.0 1.0 5 Q8NG31,P19022,Q92793,Q8WWQ0 4 +Slender build 0.2573184911123984 0.0450953012360965 0.9640313466847286 1.0 1.0 12 P06753,Q14191,Q3ZCQ8,Q15233 4 +Hepatoblastoma 0.2671024801498507 0.0448955450563969 0.96419056779598 1.0 1.0 11 Q969G3 1 +Abnormal substantia nigra morphology 0.4107656879677511 0.0447235383818145 0.9643276715517232 1.0 1.0 3 P04062,Q99700 2 +Cellular immunodeficiency 0.2571729047861355 0.0446620077665257 0.964376716872563 1.0 1.0 12 P31749 1 +Central diabetes insipidus 0.3879136690647436 0.0424087515146827 0.9661728519273708 1.0 1.0 2 O76024 1 +Mitral valve prolapse 0.2485675936180585 0.042237441395735 0.9663094152622728 1.0 1.0 23 P53701,P02545,P55795,P06753,Q96L58 5 +Soft tissue sarcoma 0.2412979644264488 0.0417735717919576 0.9666792032715356 1.0 1.0 37 Q969G3,Q13126,P31749,Q15392 4 +Atresia of the external auditory canal 0.2587402206675037 0.0415833291138173 0.9668308631860748 1.0 1.0 15 Q9H9S5,Q9Y619 2 +Macrocephaly at birth 0.3864748201438801 0.0415340391008121 0.9668701569791628 1.0 1.0 2 Q8NCE2 1 +Abnormal liver physiology 0.2962142981258698 0.040952171654286 0.967334025338238 1.0 1.0 7 Q9UJS0 1 +Everted upper lip vermilion 0.2816024589339047 0.0407710020200869 0.9674784571650176 1.0 1.0 8 O15047,O00189 2 +Gastric ulcer 0.4038572251007343 0.0387182767285695 0.9691150016124486 1.0 1.0 3 P04062,O76024 2 +Lipodystrophy 0.2408791769699224 0.0386826142808405 0.969143434828354 1.0 1.0 35 P31751,P02545,P28070,Q03252,P42166,Q9Y3Z3,O75844,Q14191 8 +Abnormal lower limb bone morphology 0.229380934797113 0.0378517198200312 0.9698059074391084 1.0 1.0 182 Q96AY3,Q9UHX1,O75718,Q32P28,Q03164,P38398,O94761,O95831,P13073,P98175,Q10713,Q14320,P25054,P02545,Q9Y619,Q08J23,O00116,Q9BXW9,P16278,P21964,O95155,P00813,P31749,Q96HY6,Q15058,Q9H9S5,O75845,Q6NUQ1,Q04721,P51812,Q8WVQ1,Q99567,Q15392,Q69YQ0,O96028,Q8N0X7,Q96L58,Q03252,O75787,Q15427,O75844,Q14191 42 +Abnormality of the hypothalamus pituitary axis 0.2274475618738073 0.036506334381058 0.9708786279719824 1.0 1.0 74 P33991,Q4J6C6,Q8IY17,Q9UHX1,P25054,Q969G3,Q03164,P48735,Q9BXW9,P42356,P57740,P31749,Q15233,Q12768,Q10713 15 +Fragile skin 0.2764101448779582 0.0357923878878029 0.9714479027651576 1.0 1.0 9 P36551,Q8NCH0 2 +Elliptocytosis 0.3998272884283052 0.0354426533492472 0.9717267736074586 1.0 1.0 3 Q8NBF2,P11171 2 +Abnormal placental membrane morphology 0.375251798561146 0.0353519439829961 0.9717991038823016 1.0 1.0 2 P21281 1 +Ectodermal dysplasia 0.375251798561146 0.0353519439829961 0.9717991038823016 1.0 1.0 2 P21281 1 +Symphalangism affecting the phalanges of the hand 0.3322787807929936 0.0345827980706593 0.9724124184459289 1.0 1.0 4 Q15233 1 +Hip subluxation 0.2932002576959164 0.0345415483965295 0.9724453112722236 1.0 1.0 7 Q03252 1 +Skin vesicle 0.2536796536796625 0.0344874245200531 0.9724884701634626 1.0 1.0 12 P50336,Q02487,P16615,O95453,Q9NX24,O60832,Q15149,Q9H488,P98194,P40763,P06748 11 +Abnormal muscle glycogen content 0.3317016988194612 0.0338930366118767 0.9729624459783784 1.0 1.0 4 P13807,Q9BUK6,P46976 3 +Hypoplastic iliac wing 0.3960852043753454 0.0325468320356367 0.9740359692301436 1.0 1.0 3 O75530,O95613 2 +Short columella 0.3960852043753429 0.0325468320356347 0.974035969230145 1.0 1.0 3 P41227,P49454 2 +Abnormality of the nail 0.2258860927468478 0.031774175990097 0.97465214080944 1.0 1.0 121 P42892,O94761,Q96L73,Q12768,O95630,P25054,P02545,Q9Y619,Q08J23,Q06136,P31749,Q15056,Q04721,P51812,P23786,P10321,P53701,O96028,Q969G3,O95453,O75844,Q96L58 22 +Abnormal blood monovalent inorganic cation concentration 0.251184572496925 0.0309781509945452 0.9752869642894167 1.0 1.0 21 Q13423,P36551,P0DP25 3 +Abnormal posterior segment imaging 0.3290980616453599 0.0308417645327679 0.9753957329688898 1.0 1.0 4 P04439,Q8WWY3 2 +Flattened femoral epiphysis 0.3651798561151033 0.0307023245271625 0.9755069373332172 1.0 1.0 2 Q14807 1 +Muscle fiber splitting 0.3637410071942399 0.0301021411930334 0.9759855930811256 1.0 1.0 2 O75190 1 +Multiple rows of eyelashes 0.3923431203223845 0.0297881062057428 0.9762360444316616 1.0 1.0 3 Q9Y606,O60716 2 +Anencephaly 0.2553476538068341 0.0296317366535816 0.9763607542314487 1.0 1.0 16 P21964,Q9Y3Z3,Q15427 3 +Areflexia of lower limbs 0.2462159712185689 0.0287847293951659 0.9770362800116033 1.0 1.0 27 O60313,Q16637,Q15120,O95394,Q13217,Q15067,Q9NR77,O75787,Q7Z5J4,Q13501 10 +Abnormality of the nasal bone 0.3880253310305007 0.0267709380095825 0.9786424330157072 1.0 1.0 3 Q6NUK1,P10644 2 +Hydranencephaly 0.3519424460431605 0.0257332219413846 0.979470125347682 1.0 1.0 2 Q92917 1 +Stage 5 chronic kidney disease 0.2438827841995928 0.0256421956692317 0.9795427298465392 1.0 1.0 30 P23786,Q14C86,P57740,Q8NFH4,Q15051,Q8N1F7 6 +Ureteropelvic junction obstruction 0.3230636337460373 0.0241468404572819 0.9807354809187034 1.0 1.0 4 Q9UJX6,P25490,Q96L73 3 +Thin skin 0.2453060887138959 0.023307873766754 0.9814046910635016 1.0 1.0 26 Q13126,Q9Y619,O75844,Q96PU5,Q96L58 5 +Coloboma 0.232035459139733 0.0227545868599723 0.9818460330707746 1.0 1.0 56 O96028,Q04721,Q9UHX1,Q8IY17,P78318,Q69YQ0,P61978,P53701,P31749,Q9H9S5,Q12768,Q10713 12 +Ureterocele 0.3415827338129446 0.0226340178051886 0.9819422084881716 1.0 1.0 2 O14936 1 +Absent hypoplastic paranasal sinuses 0.3808290155440226 0.0221235897513194 0.982349369179322 1.0 1.0 3 A6NHR9,P10644 2 +Edema of the dorsum of feet 0.332661870503592 0.0204451613626684 0.9836882578107942 1.0 1.0 2 Q9Y263 1 +Edema of the dorsum of hands 0.332661870503592 0.0204451613626684 0.9836882578107942 1.0 1.0 2 Q9Y263 1 +Periventricular nodular heterotopia 0.3779501209041548 0.020393157867112 0.983729741947859 1.0 1.0 3 Q96PU5 1 +Abnormality of the musculature of the thigh 0.2858197320727327 0.0197250911811851 0.9842626748037616 1.0 1.0 7 O14979 1 +Esophageal varix 0.3078917050691331 0.0196614870569749 0.9843134137125849 1.0 1.0 5 P35670,P04062,Q06330,Q9NSD9 4 +Abnormal cutaneous elastic fiber morphology 0.3765112262521505 0.0195550259447911 0.9843983410621208 1.0 1.0 3 P36543,P38606 2 +Abnormal circulating apolipoprotein concentration 0.3765112262521505 0.0195550259447911 0.9843983410621208 1.0 1.0 3 P36543,P38606 2 +Prominent veins on trunk 0.3765112262521505 0.0195550259447911 0.9843983410621208 1.0 1.0 3 P36543,P38606 2 +Abnormality of the cerebrospinal fluid 0.2209505060180553 0.0190708061226484 0.9847846205328086 1.0 1.0 159 Q9Y375,O43676,P00846,P38398,Q9NR77,Q9P0J0,O95831,P13073,Q12768,P20700,Q10713,Q08J23,Q8N183,Q9BXW9,O43681,P21964,Q9Y3Z3,P31749,Q9H9S5,Q04721,Q15392,Q16625,O60508,P23786,P53701,O96000,O96028,O75312,P57076,O75489,Q9NWS8,O95169,Q969G3,Q03252,Q15427,P40855,Q96L58 37 +Delayed eruption of primary teeth 0.317880794701984 0.0188075916290263 0.984994597650778 1.0 1.0 4 Q92889,Q8NC56,Q7Z5J4 3 +Sea blue histiocytosis 0.3748877322649783 0.0186304304605171 0.9851359270485438 1.0 1.0 3 O15118 1 +Proximal symphalangism 0.3746671999960926 0.0185065423104925 0.9852347584512082 1.0 1.0 3 Q15233 1 +Triangular face 0.236475644524051 0.017143303685908 0.986322292634566 1.0 1.0 41 Q96AY3,Q04721,O75381,P22681,P40855 5 +Ventricular septal hypertrophy 0.3719055843408078 0.0169892753701731 0.986445171553444 1.0 1.0 3 Q8NC56,P46976 2 +Angiokeratoma 0.3719055843408054 0.0169892753701717 0.9864451715534452 1.0 1.0 3 P16278,P04066 2 +Abnormality of the sense of smell 0.2456560582065578 0.0168213963585274 0.9865791004855942 1.0 1.0 22 Q15043,P31749,Q6Y7W6 3 +Decreased muscle mass 0.2505717629277848 0.0166598477960944 0.9867079795288992 1.0 1.0 19 O96028,P31749 2 +Gaze evoked nystagmus 0.2560112135630358 0.0156960364698379 0.9874768890475712 1.0 1.0 11 Q10713 1 +Abnormal ovarian morphology 0.2399914851458527 0.0154974612603791 0.9876353098713124 1.0 1.0 32 P31751,Q15056,O75312,P02545,Q03252,P31749 6 +Esophageal stenosis 0.295041480375827 0.015313916342846 0.9877817401494562 1.0 1.0 6 O95394 1 +Absent testis 0.3042912813217955 0.0147807262828062 0.98820711610136 1.0 1.0 5 Q9BXW9 1 +Cavum septum pellucidum 0.2550301640988527 0.0133014600242866 0.9893872833606798 1.0 1.0 11 O96028,Q69YQ0 2 +Abnormal male reproductive system physiology 0.2327516678977785 0.0106368349286749 0.9915131936709742 1.0 1.0 45 Q13423,Q15056,P57076,Q969G3,P04150,Q9BXW9,P31749,P20700 8 +Abnormal right atrium morphology 0.3572251007484048 0.0099303935406541 0.9920768225324376 1.0 1.0 3 O95235,Q14315 2 +Aplasia hypoplasia of the phalanges of the hand 0.2297727309695897 0.0097124873531969 0.9922506781294512 1.0 1.0 58 O95630,Q9UHX1,P02545,Q8WVQ1,Q04721,P51812,Q969G3,Q03164,Q9BXW9,O75844 10 +Reduced tendon reflexes 0.2280349273398556 0.0057504494540971 0.9954118304495913 1.0 1.0 184 Q96AY3,P00846,Q9NR77,Q9BQT8,O95831,O14979,Q10713,Q15067,O43681,Q9Y5Y0,Q16637,O75381,P35637,O95721,P51114,Q8IY17,Q99720,P56589,P40855,P61978 20 +Repetitive compulsive behavior 0.3445595854922174 0.0050758074087204 0.9959501090250916 1.0 1.0 3 P51608,Q01082 2 +Abnormal prostate morphology 0.2646214213152073 0.0046991793796274 0.9962506111237373 1.0 1.0 8 P25054 1 +Renal tubular atrophy 0.2962329692639285 0.0046587639009347 0.9962828576572164 1.0 1.0 5 P57740 1 +Abnormality of the pituitary gland 0.2233026326214106 0.0029956411412127 0.9976098277585684 1.0 1.0 66 P33991,Q4J6C6,Q8IY17,Q9UHX1,P25054,Q969G3,P48735,P42356,P57740,P31749,Q15233,Q12768 12 +Chronic diarrhea 0.2464733117586071 0.0019878660316446 0.998413913429006 1.0 1.0 19 P00813 1 +Short ribs 0.2583584212384654 0.0014859297892166 0.9988143999990452 1.0 1.0 10 Q96HY6,Q9Y619 2 +Depressed nasal tip 0.2977250588406337 0.0014352375635588 0.9988548465001036 1.0 1.0 4 Q03164,Q96KP1 2 +Muscular ventricular septal defect 0.3321819228554862 0.0012879887818524 0.9989723339206078 1.0 1.0 3 Q86W42,Q9Y2W2 2 +Autoimmunity 0.2346410016326904 0.0004110026050967 0.999672067376176 1.0 1.0 34 Q13546,O95394,Q03252,Q9Y3Z3,P14174,P00813 6 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..894cc5279c031c6094ace285bd2eefc9701d5372 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating aldosterone", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rapid eye movement sleep", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 2nd finger", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal interphalangeal creases", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent phalangeal crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bicoronal synostosis", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pain", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Coronary artery stenosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Decreased vigilance", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal symphalangism", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duodenal ulcer", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged interphalangeal joints", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucagonoma", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hypergastrinemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Insulinoma", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal bleeding", "Intestinal carcinoid", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "Ivory epiphyses", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large cafe au lait macules with irregular margins", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lip pit", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Moderately short stature", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non convulsive status epilepticus without coma", "Non hodgkin lymphoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell adenoma", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary cystadenoma of the epididymis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postprandial hyperglycemia", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short middle phalanx of the 2nd finger", "Short middle phalanx of toe", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Silver gray hair", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skewfoot", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Status epilepticus without prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary cusp", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Underfolded helix", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced primary teeth", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP4M1", "APC", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARMC9", "ARPC1B", "ARSA", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCL10", "BCOR", "BCS1L", "BICD2", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CASK", "CAST", "CBL", "CBX2", "CC2D1A", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CD3EAP", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK6", "CDKN2A", "CENPE", "CENPF", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHM", "CHMP1A", "CHMP2B", "CHMP4B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COASY", "COG5", "COG7", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ6", "COQ8A", "COX2", "COX4I1", "COX5A", "COX6B1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREBBP", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CTU2", "CUL3", "CUL4B", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DEGS1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB6", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DPP9", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FAH", "FAM126A", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLVCR1", "FMR1", "FOXRED1", "FRG1", "FSCN1", "FTH1", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GBA", "GCDH", "GCLC", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNAI2", "GNAI3", "GNB1", "GNE", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPI", "GPKOW", "GPT2", "GRHPR", "GSDME", "GSR", "GSS", "GSTM3", "GTF2I", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HAX1", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD13", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFT27", "IGBP1", "IGF2BP2", "IGF2R", "IMPA1", "IMPAD1", "INF2", "INTS1", "INTS8", "IQCB1", "IRF2BP2", "IRF2BPL", "IRS4", "ITCH", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KMT2A", "KNL1", "L2HGDH", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LRSAM1", "LSS", "LYRM7", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAPK1", "MAPKAPK3", "MAPRE2", "MARK3", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MDH1", "MDH2", "MECP2", "MED17", "MED23", "MEN1", "MESD", "MFN2", "MGAT2", "MIA3", "MICU1", "MID1", "MIF", "MIPEP", "MMAB", "MOGS", "MORC2", "MPDU1", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVD", "MYH14", "MYH9", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "ND4", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4L", "NEK9", "NELFA", "NEMF", "NF1", "NFS1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NR3C1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OCRL", "OFD1", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PAPSS2", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PCNT", "PDCD6", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS1", "PDSS2", "PDXK", "PEPD", "PEX11B", "PEX14", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POLR3B", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QRICH1", "QRSL1", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAC1", "RAC3", "RAD21", "RAD50", "RAI1", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "RECQL4", "RELA", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNF2", "RP2", "RPIA", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS27", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RRP7A", "RSPRY1", "RTN2", "SACS", "SALL2", "SAMHD1", "SAR1B", "SARS", "SARS2", "SASS6", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC2A1", "SLC33A1", "SLC39A14", "SLC5A6", "SLC9A3R1", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SRP54", "SRP72", "SRSF2", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STIM1", "STK4", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TAF6", "TALDO1", "TAOK1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D8B", "TBCD", "TBCE", "TBL2", "TCOF1", "TDP1", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM50", "TIMMDC1", "TJP2", "TKFC", "TKT", "TLK2", "TMCO1", "TMEM126A", "TMEM199", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRRAP", "TSFM", "TSPYL1", "TSR2", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXNDC15", "TXNL4A", "UBA1", "UBA5", "UBE3A", "UBE4A", "UBE4B", "UBIAD1", "UBTF", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC119", "UNC45A", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAC14", "VAMP7", "VANGL1", "VAPB", "VARS1", "VCL", "VCP", "VIM", "VPS11", "VPS13A", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR11", "WDR26", "WDR34", "WDR36", "WDR62", "WDR73", "WFS1", "WIPI2", "WNK1", "WRN", "XIAP", "XPNPEP3", "XRCC1", "XRCC4", "YARS", "YARS2", "YEATS2", "YIPF5", "YME1L1", "YWHAE", "YWHAG", "YY1", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF148", "ZNF644", "ZNF687", "ZPR1"], "leading_proteins": ["ABCB7", "ACAT2", "ACBD5", "ACOX1", "ACP2", "ADA", "ADD1", "ADD3", "ADK", "AGPS", "AIFM1", "AIP", "AKT1", "AKT2", "ALDH6A1", "ANAPC2", "ANKLE2", "AP4M1", "APC", "APOL2", "APP", "APPL1", "ARMC9", "ASAH1", "ASNA1", "ATAD3A", "ATIC", "ATP2A2", "ATP2C1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATXN10", "ATXN2", "B3GALT6", "B9D1", "BAZ1B", "BCL10", "BICD2", "BRCA1", "BRD4", "BUB1B", "BUD23", "C19orf70", "C1QBP", "C21orf59", "CALD1", "CALM3", "CAMK2G", "CANT1", "CASK", "CBL", "CDC40", "CDC45", "CDH2", "CDK4", "CDKN2A", "CENPF", "CERS1", "CHAMP1", "CHMP1A", "CHMP4B", "CHST14", "CIZ1", "CLN5", "CLPP", "COA3", "COASY", "COMT", "COQ6", "COX4I1", "CPOX", "CPT2", "CREBBP", "CRTAP", "CTNND1", "CXorf56", "DAXX", "DCTN1", "DDRGK1", "DGCR8", "DHCR24", "DHFR", "DHPS", "DIABLO", "DICER1", "DKC1", "DNAJB6", "DNAJC3", "DNM1L", "DSC2", "EBP", "ECE1", "EED", "EIF4H", "EMD", "EPB41", "EPHX2", "ERAP1", "ERCC4", "ESS2", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOSC2", "EXOSC3", "FAM50A", "FANCD2", "FAR1", "FARSB", "FDFT1", "FECH", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLNC", "FLVCR1", "FMR1", "FOXRED1", "FUCA1", "FUS", "FXR1", "GAPVD1", "GATAD2B", "GBA", "GIGYF2", "GLB1", "GLUD1", "GNAI3", "GNPAT", "GPKOW", "GSTM3", "GTF2I", "GUSB", "GYG1", "GYS1", "HADH", "HADHA", "HAX1", "HCCS", "HERC2", "HEXA", "HLA-A", "HLA-C", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HOXD13", "HS2ST1", "HTRA2", "IDH2", "IGBP1", "IQCB1", "IRS4", "KDM3B", "KDSR", "KIF14", "KIF20A", "KIF22", "KIFBP", "KLC2", "KMT2A", "KNL1", "L2HGDH", "LAS1L", "LBR", "LEMD2", "LEMD3", "LMNA", "LMNB1", "LMNB2", "LRSAM1", "LSS", "MAPK1", "MARK3", "MATR3", "MCCC2", "MCM3AP", "MCM4", "MCM6", "MECP2", "MIA3", "MIF", "MIPEP", "MRPS25", "MSH2", "MSTO1", "MTAP", "MTMR14", "MTX2", "NAA10", "NADK2", "NAGLU", "NBN", "NDUFA13", "NDUFA8", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFS3", "NEDD4L", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOTCH2", "NPC1", "NPM1", "NR3C1", "NSD1", "NSD2", "NSMCE3", "NSUN2", "NT5C2", "NUP107", "NUP214", "NUP37", "NUP62", "NUP88", "NUP93", "OCLN", "OPA1", "P3H1", "P4HA2", 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setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Peroxisome 14 33 2.6844155559308693 0.0072656735091587 8.944174757281553 33.31553398058252 0.1912181674752777 0.455069334940637 4.249990296795741 4.279943228040891 1.217274798105213 0.3271299230574079 0.0081080507671197 0.2648597161900051 0.1290920553826253 0.0001621519489155 3.666660274187762e-07 +Porphyrin and chlorophyll metabolism 4 14 2.3826284565210445 0.0171895335811176 3.728155339805826 13.315533980582524 1.2215621624941897 0.2689555702886888 1.770547470360957 1.4201912411596824 1.0389071586082248 0.2908939383930566 0.0062661916687399 0.0039064712270754 0.0008717411361388 0.0011993766429203 0.0022722304352638 +Steroid biosynthesis 6 13 2.2454405159959583 0.0247398668816796 4.451456310679611 10.919902912621358 0.8535439655720318 0.1867209176898754 2.1463612955879627 1.3314318120676296 1.5430058140543457 0.1933818217769055 0.2380852427705514 0.0639684350193291 0.1265462710440741 0.0439142352380576 0.00037411273114 +Mtor signaling pathway 4 14 2.076632102042881 0.0378355276593889 3.9271844660194177 12.893203883495143 -0.1175056834720911 0.5561036431268109 2.3769807958492986 2.3767180657908846 0.9104883448278088 0.3008944302982549 0.0010653984680141 1.0 0.0070463522145746 0.002945649466309 0.0476655926672988 +Non small cell lung cancer 2 14 2.0579818135171832 0.039591879219722 4.191747572815534 11.733009708737864 0.0576808424166193 0.6303879618909132 2.6493505073956896 2.427907659250551 0.7768846297907037 0.2972639098554911 0.06443512813817 1.0 1.0 0.1099245732268714 0.4168750029101466 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f0eede5c163677ea8b0f367e589d49be1ae9bbaf --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 17.955555555555556 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..dd0c5da305f3148134fb18c6711425dd1c2acc2e --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4fd0449635bac1308ef268e0251e24ec6c70c000 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,72 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peroxisome 0.5374976756207498 2.6844155559308693 0.0072656735091587 0.7308793460181697 0.1188928392407794 33 O00116,Q13011,O75521,O15228,O75381,Q15067,P48735,P56589,O14734,Q9NR77,Q9BQG2,Q9BY49,P40855,P34913 14 +Porphyrin and chlorophyll metabolism 0.6564416064803853 2.3826284565210445 0.0171895335811176 0.9558877599988174 0.1933822527875733 14 P09601,P22830,P53701,P30519 4 +Steroid biosynthesis 0.6404489250721446 2.2454405159959583 0.0247398668816796 0.9889925973781202 0.2473986688167961 13 Q16850,P37268,O75845,P48449,P35610,Q15392 6 +Mtor signaling pathway 0.6054517211785918 2.076632102042881 0.0378355276593889 0.9990342226887396 0.2747919223799243 14 Q15418,P31749,P51812,P23588 4 +Non small cell lung cancer 0.6023969947727565 2.0579818135171832 0.039591879219722 0.9993048984643512 0.2747919223799243 14 P31749,P05771 2 +Glycerophospholipid metabolism 0.5513768434868381 1.9298787762269245 0.053621859724618 0.99995083613143 0.3217311583477085 18 Q6UWP7,Q9HBU6,O15228,O75608,Q8NCC3,P35790 6 +Renin angiotensin system 0.8485670610288001 1.886394229570166 0.0592418495945605 0.99998317178215 0.3439849331297065 4 Q9UIQ6 1 +Nicotinate and nicotinamide metabolism 0.7240101790044227 1.7988301462229117 0.0720455530881631 0.9999985717694542 0.4052562361209179 6 Q9BQG2,P49902 2 +Arachidonic acid metabolism 0.8234478904107101 1.7820392424481686 0.0747428325482788 0.9999991542491496 0.4076881775360664 4 P34913,Q9H7Z7 2 +Hypertrophic cardiomyopathy hcm 0.6799790769343967 1.7397760905614452 0.0818983423549846 0.9999997909072988 0.4168831788040008 7 P67936,P06753,P16615,P02545 4 +Glioma 0.5296621008309081 1.727872462844846 0.0840110922866392 0.9999998618857086 0.4168831788040008 17 P31751,P31749,P05771 3 +One carbon pool by folate 0.6050051164716757 1.6981476670327038 0.0894798948888073 0.9999999529979096 0.4168831788040008 10 P00374 1 +Progesterone mediated oocyte maturation 0.4469707787768468 1.6531321500724414 0.0983039714535638 0.9999999918561788 0.4315784112595486 28 P31751,Q15418,P31749,P51812 4 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.7864618362957002 1.6268917131271303 0.1037600982955113 0.999999997268699 0.4446861355521915 4 Q8N6G5,Q8NCH0 2 +Metabolism of xenobiotics by cytochrome p450 0.6084034554536717 1.5671971114568406 0.1170686254352189 0.9999999998151368 0.4789171040531682 8 P07099 1 +Cardiac muscle contraction 0.4745763539208384 1.4515393427877528 0.1466297352260706 0.9999999999995977 0.5737685291454937 19 P14927,P14406,P67936,P22695,P13073 5 +Fc epsilon ri signaling pathway 0.5052253082949052 1.4185224955066615 0.1560382757569391 0.9999999999999452 0.5975933965159372 13 P31749,P05771 2 +Jak stat signaling pathway 0.5743344912896962 1.386603727392017 0.165562631109742 0.9999999999999928 0.6208598666615326 8 P31751,P31749 2 +Melanoma 0.5030367364881808 1.244660131186928 0.2132567069509523 1.0 0.6734311690139504 11 P31749 1 +Neuroactive ligand receptor interaction 0.8243812610615813 1.235682091409814 0.2165767569160128 1.0 0.6734311690139504 3 P30536 1 +Erbb signaling pathway 0.4511596302419363 1.2345595052099796 0.216994487793384 1.0 0.6734311690139504 18 P31751,P46108,P31749,P05771 4 +Sphingolipid metabolism 0.4723844164407413 1.2103696684066416 0.226137075335576 1.0 0.6784112260067281 13 O43681,Q06136 2 +Alpha linolenic acid metabolism 0.8119118903660285 1.1875143639622232 0.2350247942056265 1.0 0.6904180657060744 3 Q15067 1 +Small cell lung cancer 0.467680561600945 1.1804767127231717 0.2378106670765367 1.0 0.6904180657060744 13 P31749 1 +Endometrial cancer 0.4653895143743761 1.1659157621990397 0.2436485054714792 1.0 0.6961385870613692 13 P31751,P31749 2 +Glycosaminoglycan biosynthesis heparan sulfate 0.7810071942446026 1.1447565849619958 0.252310004268947 1.0 0.7096218870064135 2 Q96L58 1 +Riboflavin metabolism 0.575515400496273 1.0916328173651415 0.2749945255083759 1.0 0.7318460862498044 6 Q9NPH0 1 +Abc transporters 0.5141745998311094 1.0649829369091075 0.2868836513638517 1.0 0.7483921339926567 8 P08183 1 +Steroid hormone biosynthesis 0.7559712230215807 1.0417809482121625 0.2975132490212622 1.0 0.7575116892933441 2 P21964 1 +Phosphatidylinositol signaling system 0.4343578091962991 0.9898831857824968 0.3222312188583673 1.0 0.7631792025592912 14 Q8TBX8,P05771,Q10713,P0DP25 4 +Parkinsons disease 0.3063927127787518 0.8924266717200834 0.3721642803851244 1.0 0.8032346330870203 59 P21796,O43676,P06576,O95169,P00846,P14927,P14406,P45880,Q9Y277,P22695,P13073,O96000 12 +Long term potentiation 0.4103409297636198 0.8567172981787663 0.3916011409805553 1.0 0.8032346330870203 15 Q15418,P51812,P05771 3 +Dilated cardiomyopathy 0.5027637356585957 0.8559719322774444 0.3920133047758301 1.0 0.8032346330870203 7 P67936,P06753,P16615,P02545 4 +Retinol metabolism 0.5937996863718876 0.8113099510823145 0.4171876968465529 1.0 0.8059096673963213 4 O94788 1 +Vegf signaling pathway 0.3923136746783226 0.7616725591234416 0.4462554569558614 1.0 0.8258400444115118 16 P31749,P05771 2 +Acute myeloid leukemia 0.4196834893306882 0.7536302024952252 0.4510713035068949 1.0 0.8258400444115118 11 P31749 1 +Neurotrophin signaling pathway 0.3213895426154417 0.7356029634824294 0.4619723585658102 1.0 0.8258400444115118 36 P31751,P51812,P0DP25,Q15418,P31749 5 +Glycosphingolipid biosynthesis ganglio series 0.5721974796593694 0.72333685428337 0.4694729558104211 1.0 0.8258400444115118 4 P06865,O00400 2 +Basal transcription factors 0.4949737188747842 0.7102365318672541 0.4775574702207863 1.0 0.8258400444115118 6 Q00403 1 +Calcium signaling pathway 0.3729353897717455 0.6875081128074712 0.4917625901354725 1.0 0.8272641703213557 18 P21796,P05771,P45880 3 +Alzheimers disease 0.279141515003132 0.6153344049263041 0.538333900862086 1.0 0.861243590967972 63 O43676,P06576,P0DP25,O95169,P00846,P14927,P14406,P22695,P13073,O96000,P05067 11 +B cell receptor signaling pathway 0.3659267647192956 0.6138735524072684 0.5392988882465544 1.0 0.861243590967972 17 P31749,P05771 2 +Apoptosis 0.3399961222390919 0.5990802738644349 0.5491193553214437 1.0 0.861243590967972 22 O95831,P31749 2 +Aldosterone regulated sodium reabsorption 0.4052799783279992 0.5032422238238463 0.6147939817253965 1.0 0.9060171091531884 8 P05771 1 +Glycerolipid metabolism 0.3461884450175961 0.4453152671413927 0.6560919362920619 1.0 0.9198651580111312 14 P30837 1 +Base excision repair 0.3413216153844037 0.4409672637826336 0.6592366965746441 1.0 0.9198651580111312 16 Q9UGN5 1 +Chronic myeloid leukemia 0.3209093078904 0.4258247418045348 0.6702355568004881 1.0 0.9209343528556324 21 P31751,P46108,P31749 3 +Snare interactions in vesicular transport 0.3351246700437432 0.3928297403901267 0.6944452371933147 1.0 0.9240679812559572 15 Q9P2W9,O95721,O60499,Q5SQN1 4 +Thyroid cancer 0.3709288183217245 0.376056596729088 0.7068748207050737 1.0 0.9240679812559572 9 P06753,Q16204,Q92734 3 +Mapk signaling pathway 0.2703364229899176 0.3573338493774202 0.7208418923337325 1.0 0.9240679812559572 46 P31751,P51812,Q15418,P31749,P05771 5 +Toll like receptor signaling pathway 0.3302764416423095 0.346474864096363 0.7289858713091217 1.0 0.9240679812559572 12 P31751,P31749 2 +Lysine degradation 0.29468507270964 0.3399227038639905 0.7339147384281359 1.0 0.9240679812559572 27 O15047,O96028,P35610,P30837,Q9BWD1,Q9NRN7,Q8WTS6 7 +Terpenoid backbone biosynthesis 0.3259770152629827 0.3247185513934219 0.7453940929018796 1.0 0.9240679812559572 12 P35610,Q86YH6,Q5T2R2,Q9BWD1,O95749 5 +Gnrh signaling pathway 0.3227417839653845 0.3086154178821626 0.757614091239897 1.0 0.9276907239672209 12 P05771 1 +Glycosaminoglycan degradation 0.3824282056837452 0.2444752561230742 0.8068627634052417 1.0 0.9467613795770532 6 P06865,P16278 2 +Allograft rejection 0.4337961081696508 0.2369374093287247 0.8127053477161663 1.0 0.9467613795770532 4 P10321 1 +Graft versus host disease 0.4337961081696508 0.2369374093287247 0.8127053477161663 1.0 0.9467613795770532 4 P10321 1 +Autoimmune thyroid disease 0.4337961081696508 0.2369374093287247 0.8127053477161663 1.0 0.9467613795770532 4 P10321 1 +Type i diabetes mellitus 0.4036342319866588 0.2352462590255884 0.8140176037351268 1.0 0.9467613795770532 5 P10321 1 +Oxidative phosphorylation 0.2476705140173567 0.2299868139518385 0.8181020160448016 1.0 0.9467613795770532 63 O75964,O75489,O43676,P06576,O95169,P00846,P14927,P14406,P22695,P13073,O96000 11 +Cell adhesion molecules cams 0.3185211655280057 0.2291044121803254 0.8187877642399854 1.0 0.9467613795770532 11 Q16625,Q92896,P10321 3 +Prostate cancer 0.2969716313761293 0.2185987998800881 0.8269625877497258 1.0 0.9467613795770532 18 P31749 1 +Notch signaling pathway 0.3157560081771696 0.2173269721559514 0.8279535386337296 1.0 0.9467613795770532 11 Q92830 1 +Pancreatic cancer 0.2959733074883458 0.2133600995895139 0.8310460998509688 1.0 0.9467613795770532 18 P31749 1 +Long term depression 0.315510115208712 0.1700247599139157 0.8649906645530014 1.0 0.9731144976221268 10 P30154,P05771,P07948,P08754 4 +Spliceosome 0.2411086234392557 0.1622044795880213 0.8711448323154327 1.0 0.9739507442035892 105 Q07955,O75940,Q9UHX1,O60828,Q86V81,Q13595,Q9Y2W2,O75400,Q8IWX8,O95391,P62310,P62995,P38159,Q96I25,O60508,P52272,O75494,Q9P013,Q01130,Q13242,P62312,P51991,Q15427,P61978 24 +Melanogenesis 0.2875360116340314 0.1503990047134694 0.8804498264633307 1.0 0.9782775849592564 14 P05771 1 +Inositol phosphate metabolism 0.2753414399622623 0.1014430104098708 0.9191987951796332 1.0 1.0 14 Q02252,Q8TBX8,Q10713 3 +Mismatch repair 0.265519479729757 0.0706612957249061 0.9436673253405384 1.0 1.0 18 Q04837,Q9UQ84,P41440 3 +Gap junction 0.2514973645751162 0.0185523334163082 0.9851982287064598 1.0 1.0 15 P07437,P62993,P68371,Q9BUF5,P05771 5 +Renal cell carcinoma 0.2480424058022992 0.0115335137514292 0.9907977914623172 1.0 1.0 20 P31751,P31749 2 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a149d300ad1c9eb85526d930cec726a6795045a6 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APC", "APEX1", "APEX2", "APP", "APPL1", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATIC", "ATM", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "AURKA", "B3GALT6", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BCL10", "BIRC6", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CASP3", "CASP7", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC7", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CGN", "CHD8", "CHERP", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHPF2", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "COASY", "COMT", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CRNKL1", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DEGS1", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERO1A", "ESPL1", "ETNK1", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FTH1", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA2", "GGCT", "GGH", "GGPS1", "GIT1", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF2BP1", "IGF2R", "ILK", "IMPA1", "IMPDH2", "INPP4A", "IQGAP1", "IQGAP2", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KAT2A", "KDELR1", "KDELR3", "KDSR", "KIDINS220", "L2HGDH", "LAMP1", "LAP3", "LARS", "LARS2", "LCLAT1", "LCMT1", "LDHA", "LDHB", "LGMN", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LYN", "LYPLA1", "M6PR", "MAD2L1", "MAN2A1", "MAN2B1", "MAP2K1", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", 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0000000000000000000000000000000000000000..e8572ac1723b94a8c4212748de1e5ca2421fc663 --- /dev/null +++ b/msigdb_reactome/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5504896db3fd3127a91aaf04b3d0c392384be5d6b1d2851517d2ca7afd208f5b +size 161367 diff --git a/msigdb_reactome/df_merge.tsv b/msigdb_reactome/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..058048cc5c62597cbf72afc322f9ab48d98deba2 --- /dev/null +++ b/msigdb_reactome/df_merge.tsv @@ -0,0 +1,37 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Protein localization 32 75 4.482760069588042 7.368375946281702e-06 25.97087378640777 74.18203883495146 1.5594110758345356 0.2555609300308859 10.717199959161563 6.26233677332747 2.0947329132902324 0.3569924888492793 8.896678422227763e-05 0.0043644807500144 0.0477492600477574 3.095601151288181e-07 1.010661657903924e-12 +Mitochondrial protein import 16 34 3.1414744140963737 0.0016809949553784 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 0.0053890450583553 0.0026460936226537 0.018985818871393 0.0029289523616429 2.1663317247155235e-05 +Slc mediated transmembrane transport 9 23 2.540185509963333 0.011079368503633 8.672330097087379 21.910194174757283 1.4735742044813558 0.239038892478899 4.348519601656105 3.146764860695784 1.3934177975338422 0.3068823132077037 0.5817787900060889 0.3805737292783386 0.2533609509960167 0.2290317051514284 0.2219073979752139 +Metabolism of porphyrins 5 10 2.447947634321625 0.0143672534868835 2.766990291262136 9.186893203883496 1.2638611374915407 0.2204767139400954 1.3861582272503026 1.170645435718008 1.0950295956895657 0.2541910601955712 0.000259013098532 0.0028214739728005 0.0113213926532688 3.906142953800441e-05 0.0001016217979366 +Sumoylation of dna damage response and repair proteins 17 47 2.447268474396133 0.0143943572554614 14.361650485436892 43.529126213592235 -0.4301449231131675 0.6345117133747565 7.290290470205936 4.579039011148904 0.865716172169565 0.328082977476346 0.4311069073233383 1.0 1.0 0.5532013943080547 0.0311266180128976 +Class a 1 rhodopsin like receptors 3 7 2.382507051872019 0.0171952026408477 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0072083457450835 0.0043047615253927 0.0170518298819148 0.0135296171343662 0.0172333771485565 +Peptide ligand binding receptors 3 7 2.382507051872019 0.0171952026408477 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0038993066179735 0.0028214739728005 0.0113213926532688 0.0074273483269255 0.0079931710216612 +Pink1 prkn mediated mitophagy 3 9 2.3258041528834035 0.0200290010033796 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.0413755654688228 0.0771453392642774 0.1515272625734178 0.062605312422627 0.0079931710216612 +Class i peroxisomal membrane protein import 5 11 2.325378777533498 0.0200517152607306 4.300970873786408 9.604368932038836 1.1426576411245968 0.2560233101944223 2.515331441636984 1.9424437465598188 1.2133199793435778 0.2911424942178205 1.0 1.0 1.0 0.0102137155300364 0.0002049367226 +Slc transporter disorders 14 33 2.3229301398351496 0.0201829056840039 10.072815533980584 32.68689320388349 0.1121793221691444 0.6146102245245559 5.627130779592072 1.491569531804079 1.0244067182438623 0.3378443700099887 0.6503846921300606 1.0 1.0 0.3776649172031714 0.0152442441513 +Striated muscle contraction 4 5 2.2842008011488075 0.0223597325150493 2.3932038834951457 5.325242718446602 0.6053303821705729 0.3904114603068206 1.4382947114128322 1.0455841909244117 1.143829865381849 0.3284891204761319 0.2671375230127674 1.0 0.1432798584585485 0.0561137872346343 0.0007525839576665 +Bile acid and bile salt metabolism 2 7 2.262061098705774 0.0236936286450522 2.424757281553398 6.216019417475728 0.186626892267787 0.5806126455525314 1.7958065200885671 1.3668884939755577 0.8497767995987026 0.308150526237464 0.0660442901165423 0.0987043131013681 0.191600110602388 0.0983610682747182 0.0892170338783466 +Synthesis of bile acids and bile salts 2 7 2.262061098705774 0.0236936286450522 2.424757281553398 6.216019417475728 0.186626892267787 0.5806126455525314 1.7958065200885671 1.3668884939755577 0.8497767995987026 0.308150526237464 0.0556855724921307 0.0901405579438761 0.1758008751515455 0.0834574734746242 0.0708751155690715 +Mitochondrial calcium ion transport 5 16 2.232484552254465 0.0255829550832999 6.502427184466019 16.12135922330097 1.0650233237312683 0.2089377868120644 3.410790121717641 1.246287729205551 1.626144580445205 0.28031724173526 0.0607884384663988 1.0 0.1837383274168749 0.090818300458346 0.002864460747413 +Rnd2 gtpase cycle 10 18 2.2265303246813395 0.0259786800994987 4.393203883495145 16.434466019417474 0.2153574081682165 0.5011395656561803 2.3985740964780717 2.430205644003464 0.9415381736607308 0.282984964314256 0.5406390866464361 1.0 0.3209553841799009 0.6257540014635683 0.5873216584654045 +Senescence associated secretory phenotype sasp 4 25 2.190585365505802 0.0284818111289237 5.449029126213592 20.00242718446602 -0.4325000759108482 0.5814716809077577 2.677635536646619 2.663579227834292 0.7783812075103509 0.3094897984403053 0.0851420807054984 1.0 0.0949012099695084 0.0413751204339429 0.1216432455234702 +Transport of mature mrnas derived from intronless transcripts 13 37 2.184705386092904 0.0289104550252221 12.485436893203884 36.21116504854369 -0.3550698997053867 0.6571229286016341 6.764935404179153 1.6521746780936135 0.8812161356906153 0.3228743985516816 0.5667271734461978 1.0 1.0 0.2797556636969028 0.0171255123594616 +Peroxisomal protein import 9 20 2.175716205600672 0.0295764876747948 5.509708737864078 20.961165048543688 -0.2101406023902152 0.4556646045130463 2.6979681158237065 3.026332106908075 1.071934776270471 0.2891517244312681 0.016377333235605 0.2143583684675494 0.3896854720293997 0.0075944976014186 0.0001452325992069 +Mitophagy 3 13 2.1738025950509705 0.0297199635735994 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.0769843908651827 0.1071891284628969 0.2070995190727305 0.1139407547181512 0.0272826327042602 +Arachidonic acid metabolism 4 9 2.17343085298785 0.0297479048230642 2.638349514563106 7.847087378640777 -0.5144390429771322 0.3075241511545106 1.1417858581190852 1.1796890581498038 1.278188973245668 0.2472373842699668 1.743551012264361e-05 0.0814971443263516 0.0126574737404708 5.302129833761715e-05 0.0013613651941044 +Transport of the slbp dependant mature mrna 12 31 2.170912384160399 0.0299377960175339 10.322815533980584 30.57281553398058 -0.2113838159701244 0.6750134343387901 5.796731907776354 1.4217583926734303 0.8670118169659932 0.3193959539823727 0.5034087748880063 1.0 1.0 0.5870305126491255 0.0291816562890673 +Nuclear envelope breakdown 16 41 2.1197872192513447 0.0340239936146404 12.973300970873789 40.713592233009706 -0.1024410164721968 0.6694745338002839 5.8489701837492225 1.9284557202056891 0.8745911279660593 0.3250750231346003 0.0851420807054984 1.0 1.0 0.1423397245441582 0.0043344107943581 +Signaling by gpcr 7 47 2.115569306884756 0.0343814545921032 7.672330097087379 43.19417475728155 -0.5063790940198728 0.4519803054705568 4.46745636971507 6.335381081291641 1.061524478103431 0.3197009161148088 0.0432210875936575 0.249454442152862 0.1330886303833328 0.1226471117083228 0.6686058171160311 +Gastrin creb signalling pathway via pkc and mapk 1 5 2.0959796190238333 0.0360839989495633 2.1019417475728157 5.223300970873787 -0.3886444460554432 0.4412055381641779 1.2064938033730337 0.9236066791475944 1.088184116363022 0.3134692687748335 0.0287436893658769 1.0 0.0077184558590264 0.0439142352380576 0.1467539296032722 +Mrna splicing 56 151 2.0955811437859087 0.0361193633729015 48.28883495145631 142.3228155339806 -0.6040586609434766 0.555878613477235 18.528162023337615 7.100537640996984 1.2901632086040689 0.3655002719916655 0.0002696931404402 0.5915553995086068 0.0346736034177491 6.565656046702612e-07 7.546141119452845e-09 +Gpcr ligand binding 2 10 2.067360774938635 0.0387001714599875 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.0581235587880523 0.019691222561341 0.0720571885403784 0.0998367022916053 0.1847754358087514 +Sumoylation of ubiquitinylation proteins 11 26 2.048239556213844 0.0405365322970123 9.449029126213592 27.453883495145632 -0.1572884084685554 0.6545901700997189 5.461233548653461 1.7873094890722168 0.9014772608467888 0.3239621676727282 0.5316003617357711 1.0 1.0 0.616426174876278 0.0396063215160503 +Regulation of glucokinase by glucokinase regulatory protein 11 26 2.048239556213844 0.0405365322970123 9.191747572815531 26.50728155339806 -0.1342835103477938 0.6587239091779541 5.165666138527258 1.1564279570110754 0.9005781973200726 0.3228729436852376 0.4526232097391984 1.0 1.0 0.5329697587184232 0.0160305095638712 +Transport of bile salts and organic acids metal ions and amine compounds 3 5 2.034798639981061 0.0418711379848126 1.8349514563106797 3.995145631067961 1.0286208624357371 0.2748571167414633 1.258733277411433 1.3329199016551914 1.161382969627279 0.2758406238802445 1.0 1.0 1.0 0.544318157098314 0.2031992995383869 +Hcmv late events 16 38 2.0251654859983077 0.0428503743940242 10.37135922330097 35.987864077669904 -0.2604077894188442 0.6891915910802267 5.492311934470012 2.6961584143216353 0.7074004247624673 0.3052328571555278 0.3352807212842309 1.0 1.0 0.445381784247055 0.0029211533393603 +Formation of atp by chemiosmotic coupling 2 10 1.9986594896381875 0.0456452089666357 3.5898058252427183 9.805825242718448 0.4783111855246443 0.2899716869602585 2.2195497140568734 0.9063771094889388 1.382334358445268 0.2713732710506487 0.2380852427705514 0.0639684350193291 0.1265462710440741 0.290751966651369 0.0280386150660574 +Intrinsic pathway for apoptosis 3 24 1.9958995458508288 0.0459448581650023 6.075242718446602 19.116504854368937 -0.0390958219594357 0.6271851315234288 3.814467692357508 2.5921875564176178 0.8031907060196911 0.2971202414808981 0.0815136006113903 1.0 0.4014202890149608 0.1367305798708485 0.2577970441656749 +Metabolism of cofactors 2 8 1.991404134630608 0.0464364750620742 1.4004854368932038 5.589805825242719 0.8083917792774582 0.3609852370032988 1.1730384400465106 1.1078681360867626 1.0031936318469477 0.2887992775559558 0.0026839350013314 0.0021914548918381 0.0088504827764808 0.0051503840765812 0.0338099842169397 +G alpha q signalling events 2 13 1.975905531696779 0.0481654775729372 2.8567961165048543 12.349514563106796 -1.2201103518730343 0.2572818502952295 1.7477801252441654 2.6253385833016627 1.1290382202140006 0.2921395940828384 0.1335720305406766 1.0 0.1323300889211223 0.2146915796551673 0.6307796355112782 +Cristae formation 11 21 1.970527187291179 0.0487779822685627 8.475728155339805 19.805825242718445 0.8613288847471563 0.2756396593916832 3.7825471979528897 1.2052333490949263 1.5890526548766304 0.3070386069824295 0.4083005998785439 0.1197698958477507 0.2297987482657219 0.1383652025719425 0.0089325963600969 +Regulation of beta cell development 2 7 1.9682695965633443 0.0490370262136832 1.2087378640776698 3.245145631067961 0.1044895949512662 0.5566108240415543 1.0121213707598689 1.12370777052972 1.0346181797444818 0.319604358598633 0.0660442901165423 1.0 1.0 0.0153906222854723 0.0892170338783466 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b35a301a30c6d792bb237db5c633103b7c32132c --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 1410, + "title": "Average number of proteins per term", + "value": 20.72695035460993 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..cf2aff9251ffb3d03fff6a66a26b3e559ac50b75 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..47e314c939e3083fe348d103264d9dad5ade769d --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,370 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein localization 0.5719004032184657 4.482760069588042 7.368375946281702e-06 0.010335664465184 0.0006493381302661 75 Q99595,P21796,O60830,P06576,O15228,Q5JRX3,O14734,Q9NS69,Q9NR77,Q13505,P34913,Q9BY49,Q10713,O00116,O75521,Q15067,O43681,Q9UJS0,O75381,Q9Y3D6,Q8N4H5,P09601,O43765,O15254,Q13011,O95169,P56589,Q9NX63,Q5T8D3,Q9Y512,P40855,P05067 32 +Mitochondrial protein import 0.5833592240961417 3.1414744140963737 0.0016809949553784 0.9067244508049044 0.0766385171254035 34 Q99595,P21796,Q9UJS0,O60830,P06576,O95169,Q5JRX3,Q3ZCQ8,Q9NX63,Q9NS69,Q9Y512,Q8N4H5,Q13505,O43615,Q10713,O14925 16 +Slc mediated transmembrane transport 0.5814163239434766 2.540185509963333 0.011079368503633 0.9999998494686704 0.2114407372588925 23 O00400,Q70HW3,Q99808,Q15043,P30825,P53985,Q9UBX3,Q9H2J7,Q8NEW0 9 +Metabolism of porphyrins 0.7458935316104313 2.447947634321625 0.0143672534868835 0.99999999862493 0.2280454351707938 10 P30519,P22830,Q9Y5Y0,P09601,P33527 5 +Sumoylation of dna damage response and repair proteins 0.4569101167946189 2.447268474396133 0.0143943572554614 0.9999999986772264 0.2280454351707938 47 Q9BTX1,P09874,P49790,Q99567,Q9BVL2,Q96SB8,P38398,P35658,P52948,P57740,O15504,Q96MG7,Q8NFH4,P41208,Q14191,P37198,Q8N1F7 17 +Class a 1 rhodopsin like receptors 0.8157129113732459 2.382507051872019 0.0171952026408477 0.9999999999760752 0.2579280396127159 7 Q9NRV9,P42892,P05067 3 +Peptide ligand binding receptors 0.8157129113732459 2.382507051872019 0.0171952026408477 0.9999999999760752 0.2579280396127159 7 Q9NRV9,P42892,P05067 3 +Pink1 prkn mediated mitophagy 0.7398956834490673 2.3258041528834035 0.0200290010033796 0.999999999999592 0.2736336251388995 9 P21796,Q8N4H5,Q9NS69 3 +Class i peroxisomal membrane protein import 0.6918615188299011 2.325378777533498 0.0200517152607306 0.9999999999996052 0.2736336251388995 11 O75381,P56589,Q9NR77,Q9Y3D6,P40855 5 +Slc transporter disorders 0.4960039486587035 2.3229301398351496 0.0201829056840039 0.999999999999673 0.2736336251388995 33 Q9BTX1,P49790,O00400,Q99567,Q9BVL2,P35658,P53985,P52948,P11166,O15504,P57740,Q8NFH4,P37198,Q8N1F7 14 +Striated muscle contraction 0.8830645161290351 2.2842008011488075 0.0223597325150493 0.9999999999999858 0.2840290346506262 5 P67936,P08670,Q9NYL9,P28289 4 +Bile acid and bile salt metabolism 0.7895614417801708 2.262061098705774 0.0236936286450522 0.999999999999998 0.2930527753466982 7 Q9H4L5,Q9BZF3 2 +Synthesis of bile acids and bile salts 0.7895614417801708 2.262061098705774 0.0236936286450522 0.999999999999998 0.2930527753466982 7 Q9H4L5,Q9BZF3 2 +Mitochondrial calcium ion transport 0.6158209442290301 2.232484552254465 0.0255829550832999 1.0 0.3083074074141281 16 P21796,P45880,Q9Y277,Q8IYU8,Q10713 5 +Rnd2 gtpase cycle 0.595906907974555 2.2265303246813395 0.0259786800994987 1.0 0.3104232113584175 18 Q9Y2I1,Q07960,Q9Y266,Q86UP2,Q07065,Q08378,Q9Y2U8,P38159,Q15058,P51648 10 +Senescence associated secretory phenotype sasp 0.5257827481582039 2.190585365505802 0.0284818111289237 1.0 0.3306744037423019 25 Q15418,P51812,Q96DE5,P16104 4 +Transport of mature mrnas derived from intronless transcripts 0.4663709964686612 2.184705386092904 0.0289104550252221 1.0 0.3314125332159613 37 Q9BTX1,Q8N1F7,Q6UN15,P49790,Q99567,Q9BVL2,P35658,P57740,O15504,P37198,Q8NFH4,Q86V81,P52948 13 +Peroxisomal protein import 0.5674865493517322 2.1757162056006716 0.0295764876747948 1.0 0.3323802549978183 20 O00116,Q13011,O75521,O15228,O75381,Q15067,P34913,O14734,Q9BY49 9 +Mitophagy 0.6283087888926184 2.1738025950509705 0.0297199635735994 1.0 0.3323802549978183 13 P21796,Q8N4H5,Q9NS69 3 +Arachidonic acid metabolism 0.7099001061440563 2.17343085298785 0.0297479048230642 1.0 0.3323802549978183 9 Q15165,P09960,P34913,Q9H7Z7 4 +Transport of the slbp dependant mature mrna 0.4915442495413386 2.170912384160399 0.0299377960175339 1.0 0.3323802549978183 31 Q9BTX1,Q86V81,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 12 +Nuclear envelope breakdown 0.4478931023743178 2.1197872192513447 0.0340239936146404 1.0 0.3607054962153614 41 Q9BTX1,P49790,P02545,Q99567,Q9BVL2,P35658,P52948,Q9Y2U8,P57740,O15504,P42166,Q8NFH4,P05771,P37198,Q8N1F7,P20700 16 +Signaling by gpcr 0.4258546820714118 2.1155693068847556 0.0343814545921032 1.0 0.3617750072751167 47 P51812,Q15418,P42892,Q9NRV9,P31749,P05067,P05771 7 +Gastrin creb signalling pathway via pkc and mapk 0.8388561644802299 2.0959796190238333 0.0360839989495633 1.0 0.3675808069332853 5 P51812 1 +Mrna splicing 0.3264773505477049 2.0955811437859087 0.0361193633729015 1.0 0.3675808069332853 151 Q07955,O75940,Q9UHX1,Q9BUJ2,O43390,P33240,Q9UBB9,O60828,P22626,Q86V81,Q9Y2W2,Q13151,O75400,Q8IWX8,Q15459,O95391,P09651,P62310,Q92733,P62995,O75934,P38159,Q8IWZ8,Q9Y3B4,Q96I25,Q15717,P67809,Q6UN15,P35637,O60508,P52272,O75494,Q14103,Q12874,Q9P013,Q01130,Q9BZI7,P52597,Q15637,P19388,P52756,Q86U42,Q13242,P55795,Q8N684,Q9BXP5,Q8WWY3,Q92917,P62312,P51991,O75937,O95400,Q15427,P31943,O43290,P61978 56 +Rsk activation 0.8928514957086336 2.068118741442502 0.0386288587860661 1.0 0.3815891032068698 4 P51812 1 +Gpcr ligand binding 0.673008653090496 2.067360774938635 0.0387001714599875 1.0 0.3815891032068698 10 Q9NRV9,P42892 2 +Sumoylation of ubiquitinylation proteins 0.5032627208951173 2.048239556213844 0.0405365322970123 1.0 0.3941828313019824 26 Q9BTX1,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 11 +Regulation of glucokinase by glucokinase regulatory protein 0.5032627208951173 2.048239556213844 0.0405365322970123 1.0 0.3941828313019824 26 Q9BTX1,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 11 +Transport of bile salts and organic acids metal ions and amine compounds 0.8246697947618281 2.034798639981061 0.0418711379848126 1.0 0.4016211194461624 5 Q8NEW0,Q15043,P53985 3 +Hcmv late events 0.4470777917818896 2.0251654859983073 0.0428503743940242 1.0 0.4034308274513274 38 Q9BTX1,Q8N1F7,P49790,Q99816,Q99567,Q9BVL2,Q9H444,P35658,P57740,O15504,P61978,Q8NFH4,Q9HD42,P37198,P52948,Q9H9H4 16 +Heme degradation 0.8815214556072145 2.0219108462172777 0.0431855630550543 1.0 0.4034308274513274 4 P33527,P30519 2 +Abacavir transport and metabolism 0.9867625899280577 1.9990277617722043 0.0456053501788007 1.0 0.414401454667878 2 P08183 1 +Formation of atp by chemiosmotic coupling 0.6601693265457707 1.9986594896381875 0.0456452089666357 1.0 0.414401454667878 10 O75964,P00846 2 +Intrinsic pathway for apoptosis 0.5051783224184949 1.9958995458508288 0.0459448581650023 1.0 0.414401454667878 24 P31751,P31749,Q9NR28 3 +Metabolism of cofactors 0.6902893586951855 1.991404134630608 0.0464364750620742 1.0 0.414401454667878 8 P00374,Q9Y2Z9 2 +G alpha q signalling events 0.5952436479181384 1.975905531696779 0.0481654775729372 1.0 0.4268037466746502 13 Q15418,P51812 2 +Cristae formation 0.5279425611259568 1.970527187291179 0.0487779822685627 1.0 0.4268037466746502 21 O75964,P06576,P00846,Q5XKP0,O75431,Q9NX63,Q6UXV4,O75947,Q9Y512,Q13505,Q16891 11 +Creb phosphorylation 0.9792805755395684 1.968407005521582 0.0490212264909422 1.0 0.4268037466746502 2 P51812 1 +Regulation of beta cell development 0.7272094007237052 1.9682695965633443 0.0490370262136832 1.0 0.4268037466746502 7 P31751,P31749 2 +Regulation of lipid metabolism by pparalpha 0.4993466033821654 1.9500789202760729 0.0511667133057405 1.0 0.4426077654054854 24 P37268,Q9NPJ6,P23786 3 +Sumoylation of rna binding proteins 0.4514238276907704 1.919602033704339 0.0549081869817511 1.0 0.4554149626133478 33 Q9BTX1,Q8N1F7,P49790,Q99567,Q9BVL2,Q14781,P49792,P07910,P35658,P57740,O15504,P12270,P61978,Q8NFH4,P37198,P52948 16 +Apoptotic factor mediated response 0.6406711355286807 1.893407753175596 0.0583036651670265 1.0 0.4592635077402651 10 Q9NR28 1 +Processing of capped intron containing pre mrna 0.3274783245920953 1.885944848125397 0.0593023870925331 1.0 0.464535365558176 194 O75940,Q86V81,O75400,Q92733,P38159,Q96I25,Q9BVL2,P35637,P52272,O15504,P52597,P19388,P55795,Q8N684,P62312,P57740,O75937,Q15427,P31943,P82979,P35658,P33240,O60828,P22626,Q9Y2W2,Q15459,O95391,P62310,P62995,P37198,Q6UN15,Q6I9Y2,Q01130,Q9BZI7,Q15637,P52756,Q13242,Q9BXP5,P51991,O95400,P52948,P61978,Q07955,Q9UHX1,O43390,Q9UBB9,P49790,P49792,P09651,O75934,Q9Y3B4,Q15717,O60508,O75494,Q14103,Q12874,Q9P013,Q8N1F7,Q86U42,Q8WWY3,Q92917,O43290,Q15007,Q9BUJ2,P07910,Q96FV9,Q13573,Q13151,Q8IWX8,Q16629,P12270,Q8IWZ8,Q8NFH4,Q86U44,P67809,Q99567,Q9BTX1 77 +Phase i functionalization of compounds 0.5755741003337674 1.85630420797102 0.0634102096508026 1.0 0.4818604359403565 13 P07099,P30837 2 +Transport of inorganic cations anions and amino acids oligopeptides 0.647333495116394 1.8474139711935065 0.0646871658633809 1.0 0.4831835181152296 9 P30825,Q9H2J7,Q70HW3 3 +Downregulation of erbb2 erbb3 signaling 0.9450359712230216 1.8275145046965624 0.0676224473714373 1.0 0.491482736050137 2 P31749 1 +Akt phosphorylates targets in the nucleus 0.9450359712230216 1.8275145046965624 0.0676224473714373 1.0 0.491482736050137 2 P31749 1 +Runx2 regulates genes involved in cell migration 0.9450359712230216 1.8275145046965624 0.0676224473714373 1.0 0.491482736050137 2 P31749 1 +Foxo mediated transcription 0.5550274850982839 1.802663418002802 0.0714410906676283 1.0 0.5013046737338898 15 P31751,Q9NTG7,P31749,P04150 4 +Synthesis of pe 0.9678248558113915 1.7891499091914007 0.0735906761933367 1.0 0.5013046737338898 3 Q9HBU6 1 +Anchoring of the basal body to the plasma membrane 0.41939729501598 1.7769302306396724 0.0755797197701495 1.0 0.5013046737338898 39 Q96CS2,O43805,Q15154,Q9H6D7,O75935,P41208,O95684,Q15051 8 +Peroxisomal lipid metabolism 0.5663948002720223 1.7682212103834132 0.0770239296468349 1.0 0.5013046737338898 12 O75521,Q15067,O14734,Q5T8D3,Q9BY49 5 +Aurka activation by tpx2 0.419897721549573 1.7576492186995956 0.0788072132551145 1.0 0.5013046737338898 38 P07437,Q96CS2,O43805,Q15154,Q9H6D7,O75935,P41208,O95684 8 +Sumoylation of sumoylation proteins 0.4629588111718007 1.7529745601105864 0.0796063739437038 1.0 0.5013046737338898 27 Q9BTX1,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 11 +Nuclear pore complex npc disassembly 0.4491046280924408 1.7515190935145164 0.0798565353092541 1.0 0.5013046737338898 30 Q9BTX1,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 11 +Activation of bad and translocation to mitochondria 0.6286825454457028 1.748192634517301 0.0804306765778846 1.0 0.5013046737338898 9 P31749 1 +Cholesterol biosynthesis 0.5059758240250679 1.738954468569034 0.0820427721212064 1.0 0.505154186423149 20 P37268,O75845,Q16850,P48449,Q15392,Q14534,Q9BWD1,O95749 8 +Apoptotic cleavage of cellular proteins 0.4694554512224678 1.7122900396413523 0.0868432313222531 1.0 0.517150304022701 24 P49354,Q9P289,P25054,P02545,P08670,Q13813,Q13464,Q16625,P35611,Q9HAW4,P20700 11 +Regulation of localization of foxo transcription factors 0.6735820210341996 1.7084628884755977 0.0875504868192162 1.0 0.517150304022701 7 P31749 1 +Signaling by fgfr1 in disease 0.5558910873691333 1.7044798081767538 0.088291485187562 1.0 0.517150304022701 12 P62993,O95429,Q16630,Q32MZ4,Q9UBW7,O95684 6 +Mitotic prophase 0.3662189552789414 1.703653250541494 0.088445886784789 1.0 0.517150304022701 61 P16104,P35658,P20700,P49790,P02545,Q8NFH4,P30154,Q01105,P37198,Q99567,Q9BVL2,Q9Y2U8,O15504,Q9BTX1,Q8N1F7,Q9UPP1,P57740,P42166,Q08379,P52948,P05771 21 +Mitochondrial biogenesis 0.4118115585540668 1.7004811319422155 0.0890404624910501 1.0 0.517150304022701 39 O75964,Q04837,P06576,P00846,Q5XKP0,Q00059,P48735,O75431,Q9NX63,Q9NTG7,Q9Y512,Q13505,Q86X55,P00367,Q16891 15 +Interleukin 4 and interleukin 13 signaling 0.5487924133139778 1.6913451438695415 0.0907709027026908 1.0 0.517150304022701 13 P31749,P08670 2 +Formation of fibrin clot clotting cascade 0.911942446043165 1.690356511009152 0.090959769785553 1.0 0.517150304022701 2 P42785 1 +Intrinsic pathway of fibrin clot formation 0.911942446043165 1.690356511009152 0.090959769785553 1.0 0.517150304022701 2 P42785 1 +Depolymerisation of the nuclear lamina 0.6030315165204122 1.687245625300325 0.0915561316445086 1.0 0.5184503840110728 10 Q9Y2U8,P05771,P02545,P20700 4 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.6986324453121613 1.680034258752656 0.0929506503808486 1.0 0.5212525181289654 6 P31749 1 +Transport of mature transcript to cytoplasm 0.3520764149289911 1.673825342964001 0.0941649300900557 1.0 0.5220787973100764 66 Q07955,P82979,P35658,Q86V81,P49790,O95391,Q8NFH4,P37198,Q6UN15,Q99567,Q9BVL2,Q6I9Y2,O60508,O15504,Q01130,Q9BZI7,Q9BTX1,Q8N1F7,Q13242,P57740,P52948 21 +Metal ion slc transporters 0.9056115107913664 1.664026577769461 0.0961071182138137 1.0 0.5220787973100764 2 Q8NEW0 1 +Zinc transporters 0.9056115107913664 1.664026577769461 0.0961071182138137 1.0 0.5220787973100764 2 Q8NEW0 1 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.6267525185380891 1.6635898194038723 0.0961944277685127 1.0 0.5220787973100764 8 P51812 1 +Signaling by erbb4 0.6230268957902125 1.6440743173535588 0.100160852244804 1.0 0.5220787973100764 8 P46934 1 +Glycerophospholipid catabolism 0.8961151079136684 1.6244870598223455 0.1042718999050906 1.0 0.5220787973100764 2 Q8IY17 1 +Heparan sulfate heparin hs gag metabolism 0.7257890020447634 1.5986847976615468 0.1098906571984001 1.0 0.5220787973100764 5 P16278,Q96L58,P54802 3 +Fgfr1 mutant receptor activation 0.5612016679369288 1.587530563200689 0.11239253051435 1.0 0.5220787973100764 11 P62993,O95429,Q16630,Q32MZ4,Q9UBW7,O95684 6 +Ptk6 expression 0.886330935251798 1.5837009948734886 0.1132617783150489 1.0 0.5220787973100764 2 Q8IZL8 1 +Transport of small molecules 0.3049479183958333 1.583630753926313 0.1132777711575885 1.0 0.5220787973100764 167 P21796,P30519,P28070,Q93050,Q8WTV0,Q9UBX3,Q99576,Q10713,P08183,O00400,Q99808,P35610,Q92667,Q9UL46,O15118,P61289,Q9Y5Y0,Q9C0H2,Q99797,Q15043,P30825,P35611,P45880,P11166,Q9Y277,Q9H2J7,Q9HD20,Q96PU5,P49721,P09601,P98194,Q8N4V1,Q8IYU8,O00231,Q15904,O00233,P28072,Q70HW3,Q13546,Q9UEY8,Q92530,P56589,P53985,Q9Y5K8,Q5T3U5,P40855,Q8NEW0,P33527 48 +Akt phosphorylates targets in the cytosol 0.6761713637401926 1.5739509002186107 0.1154988010972375 1.0 0.5220787973100764 6 P31751,P31749 2 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.5343700608435831 1.5728669992943434 0.1157496178584578 1.0 0.5220787973100764 12 O43681,O43765,P05067,P09601 4 +Phospholipid metabolism 0.3690577725227612 1.5627317654845625 0.1181156995332726 1.0 0.5220787973100764 53 Q8IY17,Q6UWP7,Q9BTU6,Q9HBU6,Q9NPH0,O15228,Q9NZC3,Q9NQZ5,P42356,Q8TBX8,Q8NCC3,P35790,Q10713 13 +Regulation of tp53 activity through association with co factors 0.9028447729166936 1.5394148321938657 0.1237030553262596 1.0 0.5322281091174311 3 P31749 1 +Ptk6 regulates rtks and their effectors akt1 and dok1 0.8756834532374091 1.5392714914015415 0.1237380307250197 1.0 0.5322281091174311 2 P31749 1 +Initiation of nuclear envelope ne reformation 0.4920925246550022 1.5222479945491847 0.1279469534433439 1.0 0.5417573704357806 18 P02545,Q8IXJ6,Q9Y2U8,Q86XL3,P20700 5 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.7610374936103561 1.519367748944629 0.1286699552049115 1.0 0.5424728585613945 4 P00374 1 +Recruitment of mitotic centrosome proteins and complexes 0.3970525108647787 1.5082720197404416 0.1314849213361435 1.0 0.5501297895666539 37 Q96CS2,O43805,Q15154,Q9H6D7,O75935,P41208,O95684 7 +Nucleotide salvage 0.5941582213621799 1.4919157382971462 0.1357212362646491 1.0 0.5596763856984386 8 P55263 1 +Constitutive signaling by akt1 e17k in cancer 0.6296834831373569 1.491528621510402 0.1358227625309238 1.0 0.5596763856984386 7 P31749 1 +Formyl peptide receptors bind formyl peptides and many other ligands 0.8888560240785955 1.4853293733601889 0.1374565945243913 1.0 0.5599952176955133 3 Q9NRV9 1 +Carboxyterminal post translational modifications of tubulin 0.6573111915336631 1.48427525403674 0.1377359124581474 1.0 0.5599952176955133 6 Q14166,P68371 2 +Regulation of tp53 activity through acetylation 0.505457540113914 1.4821466447469538 0.1383012797780098 1.0 0.5599952176955133 15 P31751,Q9NPI1,Q8TBX8,P31749 4 +Heme biosynthesis 0.6563103991551664 1.4795030937740736 0.1390059051017231 1.0 0.5599952176955133 6 P22830,Q9Y5Y0 2 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.4852963703581625 1.4747445644732646 0.140281230052194 1.0 0.5619219726522546 18 O43852,Q02818,Q9BTY2,Q07065,P05067 5 +Organelle biogenesis and maintenance 0.3218175155640027 1.4628969557881606 0.143495577135053 1.0 0.5705183000143371 108 O75964,Q9UPN4,P06576,P00846,O43805,Q15154,Q9H6D7,Q9NV70,Q13505,O95684,Q92845,A6NIH7,Q10713,P07437,Q04837,Q9NTG7,O94927,Q96RS0,Q00059,P00367,Q5XKP0,O75431,P48735,A0AVF1,P68371,O75935,Q15051,Q86X55,Q16891,Q96CS2,Q9NX63,Q13561,O75947,Q9Y512,P41208 35 +Pre notch processing in golgi 0.6945292469508071 1.457865644365147 0.1448775799216455 1.0 0.5705183000143371 5 Q15363,Q04721,P16615 3 +Export of viral ribonucleoproteins from nucleus 0.4242161601910376 1.4563125910524493 0.1453062264187468 1.0 0.5705183000143371 28 Q9BTX1,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 11 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5378934720671327 1.4508371627862422 0.1468252087184007 1.0 0.572687206403112 11 Q96DE5 1 +Recruitment of numa to mitotic centrosomes 0.3824654952918366 1.4475131909047756 0.1477532446987 1.0 0.572687206403112 41 Q96CS2,O43805,Q15154,Q9H6D7,O75935,P41208,O95684 7 +Purine salvage 0.6438783652390943 1.4201204224120645 0.1555726256831957 1.0 0.5880895501697212 6 P55263 1 +Hur elavl1 binds and stabilizes mrna 0.6359023795716849 1.3819321616971283 0.1669925316525669 1.0 0.6147766831073611 6 Q15717,Q01105,P35658 3 +Cd28 dependent pi3k akt signaling 0.8604186237478126 1.3752107798986326 0.1690661072325423 1.0 0.6207896124944914 3 P31749 1 +Pre notch expression and processing 0.4919633730372963 1.3623704783632773 0.1730809955770533 1.0 0.627362991680322 14 Q15363,Q04721,Q13573,P16104,P16615,Q92830 6 +Endosomal vacuolar pathway 0.7236238505967904 1.3602109626010983 0.1737631744439671 1.0 0.6277032074844404 4 Q9UIQ6,P10321 2 +Signaling by cytosolic fgfr1 fusion mutants 0.5565800131970013 1.357365120182212 0.1746652252730549 1.0 0.6282601215178761 9 P62993,Q16630,Q32MZ4,Q9UBW7,O95684 5 +Hcmv infection 0.3470395487317492 1.3486381482936642 0.1774532211638255 1.0 0.6314703964781984 56 Q99816,P35658,Q9Y3E7,Q9H9H4,P49790,Q9H444,P49792,Q8NFH4,Q9HD42,P37198,Q99567,Q9BVL2,O15504,P68371,Q9BUF5,Q9UER7,Q9BTX1,Q8N1F7,P57740,P61978,P52948 21 +Ns1 mediated effects on host pathways 0.3905133718278659 1.3461788776674797 0.1782448353179595 1.0 0.6314703964781984 33 Q9BTX1,P49790,Q86U42,Q99567,Q9BVL2,P49792,P35658,P52948,P57740,P52292,O15504,P12270,Q8NFH4,P37198,Q8N1F7 15 +Meiotic synapsis 0.4732171536691023 1.3439644669944557 0.1789598774708709 1.0 0.6324146045963108 17 P02545,P16104,P38398,Q9UH99,P20700 5 +Chondroitin sulfate dermatan sulfate metabolism 0.6228978551724729 1.319542816217218 0.1869877058656897 1.0 0.6521582259941812 6 Q8N6G5,Q96L58,Q8NCH0 3 +Hdr through mmej alt nhej 0.5615736346206877 1.318542691501163 0.1873220436366265 1.0 0.6521582259941812 8 Q9UGN5 1 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4917301042170452 1.3088490801493828 0.1905854778930824 1.0 0.6588013523315321 12 Q96DE5 1 +Flt3 signaling 0.6193146763257242 1.302329967424792 0.1928036116097635 1.0 0.6626860841073674 6 P31751,P31749 2 +Defective intrinsic pathway for apoptosis 0.4754187501262045 1.284857088012952 0.1988422287571083 1.0 0.6686872032074432 15 Q07021,P05067,Q08379,P20700 4 +Ptk6 regulates proteins involved in rna processing 0.8336211859527873 1.2714252100413488 0.2035774187307857 1.0 0.6707357132026263 3 Q07666,O75525 2 +Amino acid transport across the plasma membrane 0.7015425183506143 1.2659963677095445 0.2055143826860832 1.0 0.6723324352375345 4 P30825 1 +Downregulation of erbb2 signaling 0.582172806634177 1.2536720063174978 0.2099612469082061 1.0 0.6790031150013089 7 P31749 1 +Nuclear envelope ne reassembly 0.3453863062199155 1.241772123177629 0.2143206508486976 1.0 0.6895394005436585 50 Q9BTX1,P02545,Q8IXJ6,Q9BVL2,Q9H444,P52948,Q9Y2U8,P57740,Q86XL3,P68371,Q92973,P42166,Q8NFH4,Q9BUF5,Q9Y3E7,P37198,Q8N1F7,P20700 18 +Signaling by pdgfr in disease 0.6048550186114686 1.232799110341896 0.2176507233582505 1.0 0.6899093540975874 6 Q13439,Q6UN15,O43815 3 +Establishment of sister chromatid cohesion 0.5454920884225205 1.2325670157662636 0.2177373493428556 1.0 0.6899093540975874 8 Q7Z5K2,Q29RF7 2 +Interactions of vpr with host cellular proteins 0.3782640699417701 1.2286698097627031 0.2191956298707373 1.0 0.692766657790636 33 O75475,Q9BTX1,P49790,Q99567,Q9BVL2,P17096,P49792,P35658,P52948,P57740,O15504,P12270,Q8NFH4,P37198,Q8N1F7 15 +Notch4 intracellular domain regulates transcription 0.6389204684227399 1.2054647167913972 0.2280239509819539 1.0 0.6944482763708818 5 Q92830 1 +Synthesis of pc 0.5986787637412292 1.2030781966415354 0.2289460618495316 1.0 0.6944482763708818 6 P35790 1 +Regulation of plk1 activity at g2 m transition 0.3568001583158516 1.1993264056690578 0.2304010514331729 1.0 0.6944482763708818 42 Q96CS2,O43805,Q15154,Q9H6D7,O75935,P41208,O95684 7 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.5976883284101067 1.198311544624867 0.2307957538786191 1.0 0.6944482763708818 6 Q16850,Q9NR77 2 +Ras processing 0.6370666351338025 1.1970359806946986 0.2312925308193301 1.0 0.6944482763708818 5 O75608,P49356,O60725 3 +Sumoylation of chromatin organization proteins 0.3670693559645187 1.1907974031898243 0.233733128586995 1.0 0.6944482763708818 36 Q9BTX1,Q8N1F7,P45973,P49790,Q99567,Q9BVL2,Q14781,P49792,P35658,P57740,O15504,P12270,Q8NFH4,P37198,P52948 15 +Condensation of prophase chromosomes 0.4727967792126675 1.19076355834105 0.2337464186469029 1.0 0.6944482763708818 12 Q9UPP1,Q01105 2 +Cilium assembly 0.3124879875134607 1.1907270815224738 0.2337607428179051 1.0 0.6944482763708818 69 Q15051,Q96CS2,O43805,Q15154,Q9H6D7,O75935,P41208,O95684,Q92845,A6NIH7,Q10713 11 +Collagen biosynthesis and modifying enzymes 0.4932329466931112 1.1864600855547258 0.2354406552466184 1.0 0.6944482763708818 11 O15460,P13674,O75718 3 +Beta oxidation of pristanoyl coa 0.6823301688105321 1.1840235873795275 0.2364037258790658 1.0 0.6944482763708818 4 O14734 1 +Processing of smdt1 0.4919866674921517 1.1790594593907595 0.2383745001937429 1.0 0.6958758701308024 11 Q10713 1 +Abc transporters in lipid homeostasis 0.8081465230785521 1.1729888821867154 0.2408002641352027 1.0 0.7000584998569811 3 P56589 1 +Regulation of gene expression in beta cells 0.8057398409458656 1.1637103366113457 0.2445414190317478 1.0 0.7072624484674384 3 P31749 1 +Collagen formation 0.464948766975084 1.163114544407153 0.244783031810007 1.0 0.7072624484674384 13 O15460,P13674,O75718 3 +G1 s specific transcription 0.4676402378599822 1.158574230005689 0.2466297781606186 1.0 0.7082443731292714 12 P00374 1 +Transport of vitamins nucleosides and related molecules 0.5169096747049455 1.1392648764048747 0.25459269340773 1.0 0.7199468171670007 9 Q99808 1 +Assembly of the hiv virion 0.7775539568345307 1.130492214298252 0.2582688772752368 1.0 0.7211071622932355 2 Q9H9H4 1 +Ubiquinol biosynthesis 0.7953367875647579 1.1236602653913144 0.261157179100755 1.0 0.7252950996684563 3 Q5T2R2,Q9Y2Z9 2 +Amyloid fiber formation 0.5801882353347845 1.114101871504846 0.2652354858630235 1.0 0.7315883840495119 6 P05067 1 +Nuclear events kinase and transcription factor activation 0.4565998281314944 1.1100603613110456 0.2669730166826223 1.0 0.7337854844493127 13 P51812 1 +Cohesin loading onto chromatin 0.497746397906822 1.095509060815178 0.2732936781512483 1.0 0.7431492941180945 10 Q9Y6X3,Q7Z5K2,Q9NTI5,Q29RF7 4 +Mitotic telophase cytokinesis 0.4537684134008429 1.0920757291520975 0.2747998164578793 1.0 0.7436961717425851 13 Q9NTI5,Q7Z5K2,O95235,Q29RF7,Q9Y6X3 5 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3924684932471753 1.0830542755485555 0.278784332757247 1.0 0.7463107836907389 24 Q13126,Q53EL6,P14174,P52597,O14979,P22626,P20700 7 +Ksrp khsrp binds and destabilizes mrna 0.4441421483390011 1.0784504171745073 0.2808327977067764 1.0 0.7497036503701514 15 P31749,Q92945 2 +Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.5725679323034158 1.0774667554076862 0.2812717950679504 1.0 0.7497036503701514 6 Q9NTG7 1 +Extracellular matrix organization 0.3800802579607854 1.0698181958098631 0.2847011503500498 1.0 0.7502635357205464 28 P55081,P13674,P05067,O15460 4 +Metabolism of lipids 0.288487569706001 1.0681476028618342 0.2854539358642374 1.0 0.7502635357205464 202 P37268,Q9Y2W1,Q6UWP7,Q9BZF3,Q9NPH0,O15228,O14734,Q8TBX8,Q8NCC3,P34913,Q9BY49,Q10713,O00116,Q9HBU6,O75521,P30536,Q15067,Q9NQZ5,P27544,O43681,Q9H4L5,Q06136,Q9NPJ6,Q16739,Q15392,Q9H7Z7,P23786,P35790,P50897,Q16850,O43772,Q8IY17,P48449,Q9NZC3,Q9UMR5,Q5T8D3,P09960,Q15165,Q96G23,P33527,O95749 41 +Erk mapk targets 0.4928003416640643 1.0675165025046247 0.2857386657318677 1.0 0.7502635357205464 10 P51812 1 +Mapk targets nuclear events mediated by map kinases 0.4928003416640643 1.0675165025046247 0.2857386657318677 1.0 0.7502635357205464 10 P51812 1 +Rnd1 gtpase cycle 0.4461017839319482 1.0657204522656598 0.2865500294209937 1.0 0.7509954302669166 14 Q9Y2U8,Q15058,O75976,P38159 4 +Interleukin 12 signaling 0.3844228907518843 1.0572468102332864 0.2903989613358702 1.0 0.7568623576406228 26 Q13126,Q53EL6,P14174,P52597,O14979,P22626,P20700 7 +Caspase mediated cleavage of cytoskeletal proteins 0.542019945614432 1.05180099571383 0.2928908621299033 1.0 0.759276482922434 7 P08670 1 +Activation of bh3 only proteins 0.4505069528782183 1.0516923673582796 0.2929407139785844 1.0 0.759276482922434 12 P31749 1 +Beta oxidation of very long chain fatty acids 0.5626341143044341 1.029774569230864 0.3031158412711501 1.0 0.7676102460392027 6 O75521,Q15067 2 +Apc c cdc20 mediated degradation of cyclin b 0.4438272170832593 1.0289961127609333 0.3034815015246375 1.0 0.7676102460392027 13 Q96DE5 1 +Regulation of foxo transcriptional activity by acetylation 0.768893297955992 1.0224032902495972 0.3065900639037497 1.0 0.7705792581658946 3 Q9NTG7 1 +Metabolism of folate and pterines 0.503097256181245 1.0058478249969616 0.3144887775997618 1.0 0.7845461139951242 8 P00374 1 +Interleukin 12 family signaling 0.3696328974907666 1.0054688933199594 0.3146711207215702 1.0 0.7845461139951242 29 Q13126,Q53EL6,P14174,P52597,O14979,P22626,P20700 7 +Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.530494902649556 0.994027919304159 0.320209275264117 1.0 0.7934887137476362 7 Q15067 1 +Wax and plasmalogen biosynthesis 0.6363876362551755 0.9889563379787027 0.322684504410426 1.0 0.7955308404478425 4 O15228 1 +Rhobtb1 gtpase cycle 0.4036111418448803 0.9830904810172562 0.3255629088063811 1.0 0.7955308404478425 20 P08670,P38159 2 +Purinergic signaling in leishmaniasis infection 0.5896903101854953 0.9823161622327512 0.3259441146085309 1.0 0.7955308404478425 5 P05067 1 +The nlrp3 inflammasome 0.5896903101854953 0.9823161622327512 0.3259441146085309 1.0 0.7955308404478425 5 P05067 1 +Inflammasomes 0.5896903101854953 0.9823161622327512 0.3259441146085309 1.0 0.7955308404478425 5 P05067 1 +Biosynthesis of specialized proresolving mediators spms 0.7547174334223032 0.9685530429334788 0.3327682416878808 1.0 0.8048082689192314 3 P34913 1 +Phosphorylation of the apc c 0.4334022698212417 0.9630241166890132 0.3355354207128975 1.0 0.807346319462774 13 Q96DE5 1 +Viral messenger rna synthesis 0.3428194737930778 0.9480397320967914 0.3431092276290688 1.0 0.8194291882888503 36 Q9BTX1,P19388,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 12 +Synthesis of pa 0.4526359668841083 0.9459088584818788 0.3441950748307376 1.0 0.8194291882888503 11 O15228,Q6UWP7,Q9NPH0 3 +Platelet aggregation plug formation 0.5187484148383953 0.9353464508427544 0.3496097839845713 1.0 0.8225499728636367 7 P31749 1 +Integrin signaling 0.5187484148383953 0.9353464508427544 0.3496097839845713 1.0 0.8225499728636367 7 P31749 1 +Diseases of programmed cell death 0.3614280855933325 0.9065246511522774 0.3646582232115747 1.0 0.8346884654680524 28 Q13546,P16104,Q07021,Q08379,P05067,P20700 6 +Heme signaling 0.4721320847180821 0.8938594041118302 0.3713971206414139 1.0 0.8419130869845557 9 Q96RS0,Q7Z5J4,P09601,Q96EB6,Q86X55 5 +Biological oxidations 0.3241508525270673 0.8920134077880084 0.3723857458795105 1.0 0.8427992001446386 44 O43169,P07099,P30837,Q9NUJ1 4 +Nuclear import of rev protein 0.3535712550650912 0.8901687449833038 0.3733752844489917 1.0 0.843684536976087 30 Q9BTX1,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 11 +Glycerophospholipid biosynthesis 0.3416596973572559 0.8771948549348212 0.3803808101874746 1.0 0.84477438474528 33 Q6UWP7,P35790,Q9HBU6,Q9NPH0 4 +Signaling by ptk6 0.4087893560712082 0.8704768330158191 0.3840398743286681 1.0 0.84477438474528 16 P04150,P22681,P46108,O75525,Q8IZL8,Q07666,P31749 7 +Diseases of mitotic cell cycle 0.4059316910760017 0.8514988088172322 0.3944923247370009 1.0 0.8508966770365407 16 Q9UER7,Q96DE5,Q9UJX3 3 +Dopamine neurotransmitter release cycle 0.7015827338129472 0.8232827690960893 0.4103472099760745 1.0 0.8614060667904772 2 O14795 1 +Regulation of kit signaling 0.5941623325640297 0.8128015725209937 0.4163318338121609 1.0 0.8614060667904772 4 P22681,P07948 2 +Synthesis of pips at the golgi membrane 0.4554974822736231 0.8038807105120614 0.4214658712639183 1.0 0.8614060667904772 9 Q9BTU6,Q10713 2 +Polb dependent long patch base excision repair 0.5149222353234992 0.8030085320347708 0.4219698031363315 1.0 0.8614060667904772 6 Q9UGN5 1 +Role of lat2 ntal lab on calcium mobilization 0.6958273381294939 0.8007524216095134 0.423274988017186 1.0 0.8614060667904772 2 P07948 1 +Unwinding of dna 0.4090724990489006 0.7957421460922354 0.4261819246169955 1.0 0.8614060667904772 12 P33991,P25205,Q9BRT9,Q9UJA3,Q9BRX5,Q14566,Q9Y248,O75419 8 +Iron uptake and transport 0.3719785196872355 0.7938319526135303 0.4272932684007657 1.0 0.8614060667904772 21 P30519,Q9Y5Y0 2 +Fgfr2 alternative splicing 0.3883676008064948 0.7933206763971645 0.4275910132606366 1.0 0.8614060667904772 18 Q01085,P31943,P52597,P52272 4 +Rnd3 gtpase cycle 0.3929265576772991 0.7930284038208077 0.4277612742630556 1.0 0.8614060667904772 17 Q9Y2U8,P38159,O75976,Q9NYL9 4 +Cd28 co stimulation 0.4429159733296521 0.7878123651149017 0.4308064672427942 1.0 0.862836816494801 10 P31749 1 +Signaling by notch3 0.4507832240781063 0.7785819310818475 0.4362260263146233 1.0 0.8724520526292467 9 Q92830 1 +Synthesis of leukotrienes lt and eoxins ex 0.7031854660672554 0.7767213213360208 0.437323204742488 1.0 0.8733839788320025 3 P09960 1 +Regulation of tp53 expression and degradation 0.4028886040840948 0.7720239923399822 0.4401002175544621 1.0 0.8746181963800054 13 P31751,Q9UER7,P31749 3 +Transport of connexons to the plasma membrane 0.5835228088705091 0.7692322189691534 0.4417554669465346 1.0 0.8746181963800054 4 P68371 1 +Gap junction assembly 0.5835228088705091 0.7692322189691534 0.4417554669465346 1.0 0.8746181963800054 4 P68371 1 +Downregulation of smad2 3 smad4 transcriptional activity 0.4838785817784848 0.7632185219703658 0.445333084412836 1.0 0.8778867091395666 7 P09874,Q96PU5,Q13573,O75376 4 +Mtor signalling 0.3957677914981795 0.7625116760110634 0.4457546771717529 1.0 0.8778867091395666 15 P31749,P23588 2 +Pi metabolism 0.36778698637311 0.7624489239580262 0.4457921161304465 1.0 0.8778867091395666 21 Q8IY17,Q9NZC3,Q8TBX8,Q9BTU6,Q10713 5 +Hcmv early events 0.3080072134364441 0.7378784963268422 0.4605882873125178 1.0 0.8904441820475129 45 Q9BTX1,P49790,Q99567,Q9BVL2,P49792,P35658,P52948,P57740,O15504,P68371,Q8NFH4,Q9UER7,P37198,Q8N1F7 14 +Sphingolipid de novo biosynthesis 0.3994170789926518 0.7371845815914335 0.4610101084359463 1.0 0.8904441820475129 12 Q96G23,Q06136 2 +Metabolism of nucleotides 0.3031129682309519 0.7356682807318985 0.4619325976298531 1.0 0.8910054208729041 48 P55263,Q9H773,P31939,P49902 4 +Hs gag degradation 0.6883756951788949 0.723146798828728 0.4695897000053306 1.0 0.8987557419174457 3 P16278 1 +Ctla4 inhibitory signaling 0.4492831404413033 0.7228449230084777 0.4697751643923102 1.0 0.8987557419174457 8 P31749 1 +Dna damage recognition in gg ner 0.3772685032025265 0.7170194221544025 0.4733621126695921 1.0 0.8988150847138299 18 P09874,Q9UGN5,P41208,Q99627 4 +Notch hlh transcription pathway 0.4455996594072577 0.70391520060533 0.4814855845770796 1.0 0.9051928990049096 8 Q04721,Q92830,Q13573 3 +Assembly of the orc complex at the origin of replication 0.4702197122743655 0.6970778427744462 0.4857540797295148 1.0 0.9083730138177928 7 P16104 1 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.6670503597122275 0.6904201919118765 0.4899299823807959 1.0 0.9137583004721191 2 P52292 1 +Cellular senescence 0.2970177250405725 0.6835741830806028 0.4942440916580057 1.0 0.9157479227829016 51 P51812,P16104,Q15418,Q96DE5,P20700 5 +Response to elevated platelet cytosolic ca2 0.3253616504612358 0.6638241960252047 0.5068028375697353 1.0 0.91989955887244 31 Q9Y6I9,P05067,P05771,Q8NBX0 4 +Kinesins 0.3420775555639948 0.661893505458678 0.5080394742967402 1.0 0.91989955887244 23 Q9BUF5,Q9H0H5,O95235,P68371,Q86Y91,Q92845,Q07866,Q9H0B6 8 +Alpha oxidation of phytanate 0.6710189310139395 0.6615272451672197 0.5082742481192539 1.0 0.91989955887244 3 Q9BY49 1 +Muscle contraction 0.3349136907993887 0.6591124605917862 0.5098235546583378 1.0 0.91989955887244 27 Q9NYL9,P08670,P67936,P28289,Q05682 5 +Loss of mecp2 binding ability to the ncor smrt complex 0.658129496402875 0.6571198409912653 0.5111038621473092 1.0 0.91989955887244 2 O75376 1 +Trna processing in the nucleus 0.3097270982434871 0.6530181804688933 0.5137445579391251 1.0 0.91989955887244 39 Q9BTX1,P49790,Q99567,Q9BVL2,Q9BVC5,P35658,P33240,P52948,P57740,O15504,Q52LJ0,Q8NFH4,P37198,Q8N1F7 14 +Signaling by fgfr2 0.3378297007035394 0.6519103980226073 0.5144589767023506 1.0 0.91989955887244 25 P52272,P22681,P31943,Q01085,P52597 5 +Signaling by fgfr 0.3378297007035394 0.6519103980226073 0.5144589767023506 1.0 0.91989955887244 25 P52272,P22681,P31943,Q01085,P52597 5 +Late endosomal microautophagy 0.3844135348494553 0.6475389011390958 0.5172832260561706 1.0 0.9220174708613394 12 Q9H444,P08670 2 +Vegfr2 mediated vascular permeability 0.4008691392593888 0.6465201310757739 0.5179425641101907 1.0 0.9220174708613394 11 P31749 1 +Nuclear signaling by erbb4 0.5524099049989066 0.6445682721092817 0.5192070013219174 1.0 0.9220174708613394 4 P16949 1 +Signaling by vegf 0.3147049547884433 0.623306083193506 0.533083401039046 1.0 0.9280030063368052 33 P31751,Q9UQB8,P31749,P05771 4 +M phase 0.2689416555355132 0.6031556662317357 0.5464051374720678 1.0 0.9288944535079896 217 Q9Y266,Q9UPN4,Q8IXJ6,P16104,P28070,Q7Z5K2,O43805,P35658,Q06323,Q15154,Q86XL3,Q9H6D7,Q9UJX3,Q29RF7,O95684,P20700,P07437,P02545,Q9NTI5,P49790,Q9H444,P49792,Q9UL46,P20618,P61289,Q8NFH4,P30154,Q01105,P37198,Q2NKX8,Q9NQS7,Q99567,Q9BVL2,Q8NG31,Q9Y2U8,O95235,O15504,Q96EA4,P68371,O75935,P49721,Q9BTX1,O00231,Q8N1F7,O00233,P28072,Q9UPP1,Q92530,Q96CS2,Q13561,P57740,Q71F23,P42166,Q96DE5,Q9UJX2,P41208,Q08379,Q9BS16,P52948,P05771 60 +Activation of ampk downstream of nmdars 0.5026074937948902 0.6014552083735681 0.5475368366423314 1.0 0.9288944535079896 5 P68371 1 +Processing of intronless pre mrnas 0.3702523061977428 0.601407509499421 0.5475685981975293 1.0 0.9288944535079896 15 Q8N684,Q6UN15,P33240 3 +Transcriptional regulation by small rnas 0.3033935691390496 0.5898770804542498 0.5552730610034522 1.0 0.9322386846973124 39 Q9BTX1,P19388,P49790,P16104,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 13 +Rhobtb gtpase cycle 0.3186245276535194 0.5804396579121445 0.561618167945642 1.0 0.9342957313261748 30 P08670,P62995,P38159 3 +Toll like receptor 9 tlr9 cascade 0.32930148041029 0.5726677623705104 0.566869669089729 1.0 0.9342957313261748 24 Q15418,P51812 2 +Interactions of rev with host cellular proteins 0.3090229642347077 0.571071997908025 0.5679508392153605 1.0 0.9342957313261748 33 Q9BTX1,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 11 +Transcriptional regulation by ventx 0.3592409943769931 0.5706739645986943 0.568220670355406 1.0 0.9342957313261748 17 Q96DE5 1 +Toll like receptor tlr1 tlr2 cascade 0.3361160078689673 0.57028684700798 0.5684831604103251 1.0 0.9342957313261748 22 Q15418,P51812 2 +Tysnd1 cleaves peroxisomal proteins 0.4929523151144094 0.561524410031048 0.5744400945491652 1.0 0.9342957313261748 5 Q15067 1 +Snrnp assembly 0.295068554141767 0.5457101845977862 0.5852651699969633 1.0 0.9342957313261748 42 Q9BTX1,Q16637,P49790,Q99567,Q9BVL2,P49792,P35658,P52948,P57740,O15504,Q9H814,Q8NFH4,P37198,Q8N1F7 14 +Stimuli sensing channels 0.3970472317350706 0.5413243555726448 0.5882840359193788 1.0 0.9342957313261748 10 Q9C0H2,Q99576,Q13546,Q96PU5 4 +Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.4048493131491039 0.5393728584870138 0.5896296050119039 1.0 0.9342957313261748 9 Q96B01,Q14191,Q9UQ84 3 +Resolution of d loop structures 0.4048493131491039 0.5393728584870138 0.5896296050119039 1.0 0.9342957313261748 9 Q96B01,Q14191,Q9UQ84 3 +Myoclonic epilepsy of lafora 0.6244604316546731 0.5361866509661766 0.5918295583693756 1.0 0.9342957313261748 2 P46976 1 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.3616122728650371 0.5349251074721896 0.5927016458979337 1.0 0.9342957313261748 14 P31749 1 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.2648444068114783 0.5088227690825945 0.610876458097757 1.0 0.9446728642538096 67 O75964,O43676,P06576,O95169,Q8N183,P00846,Q16134,P14927,Q9P0J0,P22695,P13073,O96000 12 +Transcriptional activation of mitochondrial biogenesis 0.3493145864734481 0.5076591100394441 0.6116924291232115 1.0 0.9446728642538096 17 Q04837,P06576,P48735,Q00059,Q9NTG7,Q86X55,P00367 7 +Diseases associated with glycosaminoglycan metabolism 0.4791158596618724 0.5055233307313832 0.6131913160282658 1.0 0.9450903716923968 5 Q96L58,Q8NCH0 2 +Smooth muscle contraction 0.3747397034061142 0.5030436802985865 0.6149335620972878 1.0 0.9465680377261744 11 P67936,Q05682 2 +Pi3k akt signaling in cancer 0.3569338683708956 0.4971568065846742 0.6190784780678742 1.0 0.9476412617241032 13 P31749 1 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3549233352244146 0.4956151386820832 0.6201659698635962 1.0 0.9476412617241032 14 Q96DE5 1 +Apc cdc20 mediated degradation of nek2a 0.3549233352244146 0.4956151386820832 0.6201659698635962 1.0 0.9476412617241032 14 Q96DE5 1 +E3 ubiquitin ligases ubiquitinate target proteins 0.3434707833556233 0.4926054953322151 0.6222913643859505 1.0 0.9494033883553932 18 O75150,O75381,P04439,Q8N7H5,Q9NS91 5 +Selective autophagy 0.2995156627922111 0.4851627930524843 0.627560872547658 1.0 0.9494033883553932 33 P21796,Q8N4H5,P08670,Q9NS69 4 +Effects of pip2 hydrolysis 0.5090699683271076 0.4803911888010742 0.6309492584659688 1.0 0.9494033883553932 4 Q8NCG7,Q05655,Q8N2K0 3 +Metabolism of fat soluble vitamins 0.4714698951205224 0.4752664159690012 0.6345970933870877 1.0 0.9494033883553932 5 Q6NUM9,P29375,Q9Y5Z9 3 +Regulation of signaling by cbl 0.4414163568179166 0.4726818988270438 0.6364401425961459 1.0 0.9494688507323968 6 P46108 1 +Regulation of tp53 activity 0.2752238876247821 0.4718700781241097 0.6370195268034378 1.0 0.9494688507323968 56 P31751,Q9UER7,Q9UQ84,Q9NPI1,P38398,O95983,Q8TBX8,Q92804,Q9ULW0,P31749,Q14191 11 +Synthesis of pips at the early endosome membrane 0.4193201302606513 0.4615908674097727 0.6443747449631654 1.0 0.954083926909526 7 Q96PE3,O00443,Q9NYA4,Q9BTU6 4 +Formation of incision complex in gg ner 0.3382037616993069 0.4389982951233033 0.6606627716618989 1.0 0.963324206869987 17 P09874,Q9UGN5 2 +Cell death signalling via nrage nrif and nade 0.3475587536669412 0.4376513552840149 0.6616390373519332 1.0 0.9637510771345308 12 Q13501,Q9NY61 2 +Sphingolipid metabolism 0.3048699899258255 0.4303842201799301 0.6669161720746701 1.0 0.9701869163753932 28 O43681,Q96G23,Q06136 3 +Regulation of hsf1 mediated heat shock response 0.2699533142376305 0.4203360274963614 0.6742399944197588 1.0 0.9701869163753932 57 P48723,Q9BTX1,Q8N1F7,P49790,O95429,Q99567,Q9BVL2,Q8N163,P35658,P52948,P57740,O15504,Q8NFH4,Q96EB6,P37198,Q9UL15 16 +Atf4 activates genes in response to endoplasmic reticulum stress 0.3406137058364034 0.4060427088451042 0.6847112198713685 1.0 0.9701869163753932 13 Q92945,Q5RKV6,O95453,Q13868 4 +Negative regulation of the pi3k akt network 0.3381247786712301 0.400048771995968 0.6891205945901704 1.0 0.9701869163753932 14 P31751,P30154,P31749,Q8TBX8 4 +Recycling pathway of l1 0.3156120648457562 0.3902404417280884 0.6963587593390721 1.0 0.9756934810721544 21 P51812 1 +Disorders of transmembrane transporters 0.2572810864732122 0.3878807542294605 0.6981042811979128 1.0 0.9756934810721544 77 P28070,P35658,Q06323,P49790,O00400,P49792,Q9UL46,P61289,Q8NFH4,P37198,Q99567,Q9BVL2,P11166,O15504,P49721,Q9BTX1,Q8N1F7,O00231,O00233,P28072,Q92530,P53985,P57740,P52948 24 +Meiosis 0.3018282148266207 0.3830925193699669 0.7016511660032592 1.0 0.9756934810721544 26 P02545,P16104,P38398,Q9UH99,P20700 5 +Reproduction 0.3018282148266207 0.3830925193699669 0.7016511660032592 1.0 0.9756934810721544 26 P02545,P16104,P38398,Q9UH99,P20700 5 +Pkmts methylate histone lysines 0.3179383445900342 0.377891373776615 0.7055112908644421 1.0 0.9756934810721544 20 O15047,O96028,Q9H7B4,Q03164,Q9UBL3,Q96L73,Q8WTS6 7 +Nonhomologous end joining nhej 0.3175519866873298 0.3754188281663935 0.7073490043492623 1.0 0.9756934810721544 20 P12956,P16104 2 +Rhobtb3 atpase cycle 0.4781259265542091 0.372640920002401 0.7094157131340655 1.0 0.9758345152819232 4 Q15345 1 +Antigen activates b cell receptor bcr leading to generation of second messengers 0.4774783116809189 0.3704890049204664 0.7110181674506828 1.0 0.9758345152819232 4 P07948 1 +Synthesis of pips at the plasma membrane 0.3489417306739317 0.3700934894534299 0.711312832926275 1.0 0.9758345152819232 11 Q96PE3,Q96T51,Q8TBX8,Q9BTU6,Q8NCE2 5 +Deactivation of the beta catenin transactivating complex 0.331924789428644 0.3660929319858 0.7142957314396345 1.0 0.9787725766082456 14 P31751,P31749 2 +Homology directed repair 0.2691494706939517 0.3637594330433821 0.7160376580090946 1.0 0.9793805439102388 48 O96028,P09874,Q9UQ84,P16104,Q9UGN5 5 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.3329311384875554 0.3601036300639929 0.7187696382497923 1.0 0.9810892448520884 12 O43681,P49366,O60725 3 +Myd88 independent tlr4 cascade 0.3013539449764947 0.3585742744547992 0.7199135946693089 1.0 0.9812990470027512 23 Q15418,P51812 2 +Bmal1 clock npas2 activates circadian gene expression 0.4386355546438398 0.3519850449146524 0.7248494781313519 1.0 0.9818774848312788 5 Q86X55,P43490 2 +Rhod gtpase cycle 0.294718238913279 0.3514754826317116 0.7252316626928068 1.0 0.9818774848312788 28 Q07960,P50402,O15173,Q9UEY8,Q86YQ8,Q5JTV8,Q9H0H5,Q9Y2U8,P42166,Q96C19,P12814,P20700 12 +Negative regulation of met activity 0.3929624748671502 0.3497596513817759 0.726519082231843 1.0 0.9818774848312788 7 P22681,P18031,O14964 3 +Ncam signaling for neurite out growth 0.410832613079808 0.3486703539696905 0.7273368032593144 1.0 0.9818774848312788 6 P62993,P28482,Q13813,Q01082,Q05397 5 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3047481718411737 0.3481819720009124 0.7277035259919762 1.0 0.9818774848312788 22 P09874,Q9UGN5 2 +Sirt1 negatively regulates rrna expression 0.4698781163680939 0.3455821193068559 0.7296567856766158 1.0 0.9826323474728064 4 P16104 1 +Rhobtb2 gtpase cycle 0.3119657235558985 0.3400894536658114 0.7337891636935747 1.0 0.9829965607526566 20 P62995,Q9NYL9,P38159 3 +Dual incision in gg ner 0.2968166020877563 0.3381168417743178 0.7352751392981547 1.0 0.9829965607526566 25 P09874,Q9UGN5 2 +Autophagy 0.2649760860586312 0.3312927943996889 0.7404233335336361 1.0 0.9849454116162828 52 P21796,P08670,Q9Y4P1,Q9H444,Q9NS69,Q13501,Q8N4H5 7 +Interferon alpha beta signaling 0.3538069007441463 0.3295902901184097 0.7417095603799544 1.0 0.9849454116162828 10 P04439,Q9Y3Z3,P10321 3 +Growth hormone receptor signaling 0.405646787669262 0.3287758487334985 0.7423251190961846 1.0 0.9849454116162828 6 P27361,P18031,P28482,P40763,P07948 5 +Extra nuclear estrogen signaling 0.3220128739040084 0.3135099953537442 0.7538932279970205 1.0 0.9869179911442978 14 P31749 1 +Glycosaminoglycan metabolism 0.316662749569808 0.3129432175106976 0.7543238025977992 1.0 0.9869179911442978 17 Q8N6G5,P06865,P16278,Q8NCH0,Q96L58,P54802 6 +Signaling by interleukins 0.2480791376852563 0.3112196652928961 0.7556336341287968 1.0 0.9869179911442978 114 Q13126,P28070,Q13501,O14979,P22626,P20700,Q53EL6,Q9UL46,P31749,P51812,P08670,Q15418,P49721,P09601,P52597,O00233,P46108,P14174,P05067 19 +Methionine salvage pathway 0.4589808481440456 0.3110358315607066 0.7557733820347723 1.0 0.9869179911442978 4 Q13126 1 +Base excision repair 0.2875151803481932 0.3093280956550387 0.7570719610139878 1.0 0.9869179911442978 29 P09874,Q9UGN5,P16104 3 +Synthesis of very long chain fatty acyl coas 0.4001728608470249 0.3081785305133785 0.7579464881335902 1.0 0.9869179911442978 6 P33121,O95573,Q53GQ0,Q9P035,Q9NZ01 5 +Mucopolysaccharidoses 0.4577980374734955 0.3073722546224329 0.7585600442670788 1.0 0.9869179911442978 4 P16278 1 +Toll like receptor cascades 0.2824040900766211 0.2990036162886853 0.7649372863119837 1.0 0.989570946710924 31 Q15418,P51812 2 +Diseases of dna repair 0.3207639603790455 0.2988883768874832 0.7650252158690929 1.0 0.989570946710924 12 Q96B01,Q14191,Q9UQ84 3 +Dna damage reversal 0.4228110599078459 0.2970987532605481 0.7663911161761199 1.0 0.989570946710924 5 Q8N9N2,Q9H1I8,Q6P6C2,Q9C0B1 4 +Deposition of new cenpa containing nucleosomes at the centromere 0.3190778752474721 0.2935976821034494 0.7690653471774807 1.0 0.9921154066973904 13 Q71F23,Q9BS16,P16104 3 +Nucleotide biosynthesis 0.3184033537631545 0.2873986475999625 0.7738070966000146 1.0 0.9953488405184244 12 P31939 1 +Activation of nmda receptors and postsynaptic events 0.2950867484555646 0.2847869658319893 0.7758073586735805 1.0 0.9953488405184244 22 P51812 1 +Rna polymerase ii transcription termination 0.2609313986519042 0.2796177576276177 0.7797707817337283 1.0 0.9977103468643892 47 Q07955,Q6UN15,Q6I9Y2,Q13242,Q8N684,O60508,O95391,Q01130,Q86V81,P82979 10 +Metalloprotease dubs 0.3915112402848025 0.2764765670542392 0.7821820552726657 1.0 0.9998882120892644 6 O95630 1 +Regulation of tlr by endogenous ligand 0.5338129496402839 0.2624857993566186 0.7929469321304488 1.0 1.0 2 O60443 1 +G alpha i signalling events 0.2861192457031461 0.2589794331837627 0.7956511092102543 1.0 1.0 24 Q9NRV9 1 +Runx2 regulates bone development 0.4107142857142917 0.2574509485424133 0.7968306766894366 1.0 1.0 5 Q96PK6,P28482,P06400,P07947 4 +Mitotic prometaphase 0.2470572563709243 0.2544473711556662 0.7991499579828685 1.0 1.0 107 Q9Y266,Q9UPN4,Q7Z5K2,O43805,Q15154,Q9H6D7,Q29RF7,O95684,P07437,Q9NTI5,P49792,O94927,Q8NFH4,P30154,Q2NKX8,Q9NQS7,Q8NG31,Q96EA4,P68371,O75935,Q9BUF5,Q96CS2,Q96BD8,Q13561,P57740,Q71F23,P41208,O60566,Q9BS16,P52948 30 +Budding and maturation of hiv virion 0.3102852985772267 0.2507631232866064 0.801997254094339 1.0 1.0 13 Q99816,Q9H444,Q96PU5,Q9Y3E7,Q9H9H4 5 +Dna double strand break repair 0.2511984786590113 0.2470815362017554 0.8048451227851703 1.0 1.0 61 O96028,P09874,Q9UQ84,P16104,P12956,Q9UGN5 6 +Hiv life cycle 0.2481222853275914 0.2468620140020063 0.8050150150469373 1.0 1.0 84 Q8IXH7,P18615,Q99816,P50750,P35658,P29083,P12956,Q14241,Q9H9H4,Q00403,P49790,Q9H444,Q8NFH4,P37198,O75475,Q99567,Q9BVL2,O15504,Q92804,Q9BTX1,Q8N1F7,P19388,P57740,Q96PU5,P52948 25 +Signaling by kit in disease 0.4055299539170593 0.2411167667261098 0.8094646181189682 1.0 1.0 5 P40763,P62993,P07948,P07947 4 +Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3078678669942287 0.2377929159789928 0.8120417133295883 1.0 1.0 12 P09874,Q13573,P50750,Q96PU5,O75376 5 +Perk regulates gene expression 0.3044656312016861 0.2308327978915377 0.8174447001904457 1.0 1.0 15 Q92945 1 +Transcriptional regulation of granulopoiesis 0.3601774093372732 0.2247148623272181 0.8222011018258026 1.0 1.0 7 P16104 1 +Polo like kinase mediated events 0.3980414746543879 0.2182538052892808 0.8272313648347613 1.0 1.0 5 O95067,P49454,Q09028,P14635 4 +Activation of atr in response to replication stress 0.2840979279529505 0.2164175876529842 0.8286622581346652 1.0 1.0 22 Q14566,Q9Y619 2 +Interaction between l1 and ankyrins 0.5191394724723872 0.2126074694433738 0.8316331448709648 1.0 1.0 3 Q13813 1 +Postmitotic nuclear pore complex npc reformation 0.2829565459749461 0.2095673039134388 0.8340054006348265 1.0 1.0 22 Q8NFH4,Q9BVL2,P52948,P57740,P37198,Q9BTX1,Q8N1F7 7 +Abc family proteins mediated transport 0.2513097078387316 0.2078255875259366 0.8353651528383521 1.0 1.0 56 P08183,O00233,P28072,P28070,Q92530,P56589,Q9UL46,P61289,P40855,P49721,P33527,O00231 12 +Recognition and association of dna glycosylase with site containing an affected purine 0.4224622183374511 0.2064310180237351 0.8364542436930726 1.0 1.0 4 P16104 1 +Miscellaneous transport and binding events 0.3543047495523992 0.204283851688397 0.8381316883779897 1.0 1.0 7 Q8N4V1,P35611 2 +Interleukin 17 signaling 0.2930522435327394 0.1982199022750981 0.8428730166586758 1.0 1.0 18 P51812 1 +Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0.333559078322351 0.1967255166710073 0.844042340861666 1.0 1.0 8 O95619 1 +Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.3107470422213632 0.1964849505546255 0.8442306108046791 1.0 1.0 11 O15047,Q03164,P16104 3 +Runx3 regulates p14 arf 0.501870503597118 0.1896713702826427 0.8495666567367497 1.0 1.0 2 P25440 1 +Costimulation by the cd28 family 0.294449556820066 0.1833873565951126 0.8544940956165445 1.0 1.0 15 P31749 1 +Transcriptional regulation by e2f6 0.2954888845210632 0.1833781171455785 0.8545013447094381 1.0 1.0 13 O75530,Q13185,P45973,P38398,Q99496 5 +Synthesis of pips at the late endosome membrane 0.3842165898617569 0.1784196904833168 0.8583933866290947 1.0 1.0 5 Q13614,Q9NYA4,Q08AM6,O00443 4 +Transcriptional regulation of white adipocyte differentiation 0.2921354837296144 0.1773283902437181 0.8592504519677742 1.0 1.0 16 Q9NPJ6,Q9Y2W1,Q96RS0,Q9NVC6,Q86X55,O75376 6 +Coenzyme a biosynthesis 0.4955395683453194 0.1769122301677373 0.8595773318669084 1.0 1.0 2 Q13057 1 +Ire1alpha activates chaperones 0.2731654409091217 0.1764032828292595 0.8599771257835238 1.0 1.0 24 P35611,P43307,Q9NWM8,Q8N6T3,P51858 5 +Linoleic acid la metabolism 0.4915107913669023 0.1690861674668706 0.8657288650326538 1.0 1.0 2 O95864 1 +Caspase activation via extrinsic apoptotic signalling pathway 0.4072954968992481 0.1685738210069742 0.8661318736436412 1.0 1.0 4 Q13546 1 +Endosomal sorting complex required for transport escrt 0.291685730939715 0.1670898611439948 0.8672993435015777 1.0 1.0 13 Q99816,Q9H444,O14964,Q9Y3E7,Q9H9H4 5 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.3775045640434282 0.1602383722497033 0.8726933032248188 1.0 1.0 5 P10321 1 +Synthesis of dolichyl phosphate 0.4846043165467582 0.1562023944586321 0.8758734893994089 1.0 1.0 2 P53602 1 +Hiv transcription initiation 0.28753103723723 0.1561704153469654 0.8758986957124342 1.0 1.0 16 Q00403,P29083,Q92804 3 +Interleukin 7 signaling 0.4834532374100675 0.1541205116524822 0.8775147155452498 1.0 1.0 2 P40763 1 +Resolution of abasic sites ap sites 0.2688300590944919 0.1523280110819374 0.8789282330630348 1.0 1.0 25 P09874,Q9UGN5 2 +Regulation of pten stability and activity 0.2480793346083178 0.1449857267844209 0.884722141086911 1.0 1.0 46 P31751,O00233,P28072,P28070,O00231,Q9UL46,P61289,P49721,P31749,P46934 10 +Signaling by flt3 fusion proteins 0.3663813013938676 0.1318413809995824 0.8951097549144864 1.0 1.0 5 Q9UBW7,P62993,Q14789 3 +Regulation of innate immune responses to cytosolic dna 0.4763960852043585 0.1291131699710926 0.897268101105809 1.0 1.0 3 P19474,Q9UJV9 2 +Met activates ras signaling 0.3855456377771344 0.1204989096319321 0.904087943340266 1.0 1.0 4 Q96S59,P62993,Q96P70 3 +Mrna decay by 3 to 5 exoribonuclease 0.2770133720620966 0.1105837236301804 0.911946454976572 1.0 1.0 16 Q969T7 1 +Gene silencing by rna 0.2425510003291451 0.1068431092426491 0.914913446963155 1.0 1.0 48 Q9BTX1,P19388,P49790,P16104,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,Q8WYQ5,P37198,Q8N1F7 14 +Unfolded protein response upr 0.2483841919068797 0.1059164942028805 0.9156486072000712 1.0 1.0 41 P02545,P35611,P43307,Q9NWM8,Q8N6T3,P51858,Q5RKV6,Q92945 8 +Trafficking and processing of endosomal tlr 0.4451798561151037 0.0954118412167927 0.9239877110565796 1.0 1.0 2 P14625 1 +Fcgr activation 0.440287769784168 0.08934105798502 0.92881086495875 1.0 1.0 2 P07948 1 +2 ltr circle formation 0.3293983163120556 0.0870618569094253 0.9306223439976592 1.0 1.0 6 O75475,P12956 2 +Signaling by mapk mutants 0.4371223021582686 0.0855787974654683 0.9318012537856026 1.0 1.0 2 Q99956 1 +Inlb mediated entry of listeria monocytogenes into host cell 0.324653113774515 0.0756798162831664 0.9396738342067924 1.0 1.0 6 P22681,O14964 2 +Signalling to ras 0.358479700547078 0.0712340003997846 0.9432115217329562 1.0 1.0 4 P11233,Q16644,P62993 3 +Sumoylation of dna replication proteins 0.2454537430444775 0.0695440651180873 0.9445565586419812 1.0 1.0 35 Q9BTX1,Q9NQS7,P49790,Q99567,Q9BVL2,P35658,P52948,P57740,O15504,Q8NFH4,P37198,Q8N1F7 12 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.2652655556940446 0.0668692644384844 0.9466857816779904 1.0 1.0 13 P05067 1 +Transferrin endocytosis and recycling 0.264162032266799 0.0662943493371203 0.9471434819057304 1.0 1.0 12 Q15904,P36543,Q93050,Q9Y5K8 4 +Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.3523846878312966 0.061756653427309 0.9507566231143684 1.0 1.0 4 Q13546 1 +Insulin receptor recycling 0.2724815633050736 0.0604620901400918 0.9517876082716024 1.0 1.0 11 Q15904,P36543,Q93050,Q9Y5K8 4 +Glycosphingolipid metabolism 0.2631777762666561 0.0567973380727943 0.9547066344271556 1.0 1.0 16 P06865,Q16739,O43681 3 +Mecp2 regulates transcription of neuronal ligands 0.4188255613125985 0.0523735918341457 0.9582310158934402 1.0 1.0 3 Q96ST3,P51608 2 +Homologous dna pairing and strand exchange 0.2606963748982348 0.048744606928668 0.9611228269168768 1.0 1.0 17 Q96B01,Q14191,Q9UQ84 3 +Transcription of the hiv genome 0.2464439107612253 0.0466223163577718 0.9628142454866336 1.0 1.0 31 Q00403,Q8IXH7,P19388,P18615,P29083,Q14241,Q92804 7 +Regulation of pyruvate dehydrogenase pdh complex 0.2834054743071524 0.0450408145395758 0.9640747766502928 1.0 1.0 8 Q15118,Q15120 2 +Signal attenuation 0.4104778353482932 0.0444632917514165 0.9645351119617968 1.0 1.0 3 P62993,P28482 2 +Adenylate cyclase inhibitory pathway 0.3902158273381249 0.0438489077186043 0.965024841827362 1.0 1.0 2 P08754 1 +Inla mediated entry of listeria monocytogenes into host cells 0.3879136690647436 0.0424087515146827 0.9661728519273708 1.0 1.0 2 O60716 1 +Met activates pi3k akt signaling 0.3853237410071896 0.0408481277596793 0.9674169709496993 1.0 1.0 2 P62993 1 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.4052964881980285 0.0399283400691691 0.9681502570058168 1.0 1.0 3 P40763,P62993 2 +Interleukin 2 family signaling 0.4052964881980287 0.0399283400691691 0.9681502570058168 1.0 1.0 3 P40763,P62993 2 +Sumoylation 0.2306259318587262 0.0363526902071034 0.9710011369677232 1.0 1.0 83 P04150,P38398,P35658,Q96MG7,P49790,Q92841,Q8NFH4,P37198,Q9NQS7,Q99567,Q9BVL2,O15504,Q9UER7,Q9BTX1,Q8N1F7,P45973,P09874,Q96SB8,P57740,P41208,P61978,Q15424,Q14191,P52948 24 +Enos activation 0.3172818675021565 0.0334614482552872 0.9733066084396323 1.0 1.0 5 P31749 1 +Hdr through homologous recombination hrr 0.2470486020109482 0.0320811451002825 0.9744073397006704 1.0 1.0 26 Q9Y2S7,Q9UQ84,P41440,Q96B01,Q14191 5 +Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 0.3880253310305022 0.0267709380095833 0.9786424330157064 1.0 1.0 3 Q32MZ4,Q92793 2 +Keratan sulfate degradation 0.3229276667790661 0.0240019730105573 0.9808510349266284 1.0 1.0 4 P06865 1 +Sumoylation of dna methylation proteins 0.3222120991606594 0.0232438573005894 0.9814557549792644 1.0 1.0 4 Q14781,Q8IXK0 2 +Rora activates gene expression 0.3099597772489606 0.0225669783334265 0.9819956845885724 1.0 1.0 5 Q86X55,Q96RS0 2 +Signaling by notch 0.2260644201845476 0.0206463960828623 0.9835277296201048 1.0 1.0 65 Q15363,P67809,Q04721,O00233,P28072,P16104,P28070,Q9UL46,P61289,P49721,P31749,Q92830,O00231 13 +P38mapk events 0.3583765112262332 0.0104258488995575 0.9916815268307362 1.0 1.0 3 P11233,Q16644 2 +Listeria monocytogenes entry into host cells 0.2675122513692763 0.0103142392519268 0.991770573657292 1.0 1.0 8 P62993,Q99961,P35222,P22681,O14964,Q9NWH9,O60716 7 +G2 m dna damage checkpoint 0.2361768363586035 0.0084876768854048 0.9932278949673012 1.0 1.0 35 Q9UQ84,P16104 2 +Nade modulates death signalling 0.3419439820791621 0.0042012858469649 0.9966478687484912 1.0 1.0 3 P42575 1 +Flt3 signaling in disease 0.2765130460382776 0.0028100514750301 0.9977579062637534 1.0 1.0 7 P22681,Q9UBW7,Q14789 3 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8e796394b247aa451a02e583260440e01b4a225c --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the phototransduction cascade", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodeling of dag and tag", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of cell death genes", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Olfactory signaling pathway", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory perception of taste", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by membrane tethered fusions of pdgfra or pdgfrb", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP4M1", "APC", "APEH", "APEX1", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8A", "ARMC8", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCL10", "BCS1L", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CENPE", "CENPF", "CENPI", "CENPK", "CENPM", "CENPU", "CEP131", "CERS1", "CERS2", "CERS5", "CETN2", "CFL1", "CGN", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLSPN", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "COASY", "COG5", "COG7", "COLGALT1", "COMMD2", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ6", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2L", "COX7C", "CPD", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSN1", "DSP", "DST", "DTL", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC3", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF2", "FAH", "FAM114A2", "FAM120B", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXL18", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLVCR1", "FN3KRP", "FNBP1L", "FNTA", "FNTB", "FSCN1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GINS1", "GINS2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAUS7", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "IPO5", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT2A", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LCMT1", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG3", "LIMD1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC1", "LRRC41", "LRRC8A", "LRRFIP1", "LRSAM1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYN", "LYPLA1", "LZTFL1", "M6PR", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MARC1", "MARCKS", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED17", "MED23", "MED24", "MED4", "MEN1", "METAP2", "METTL1", "METTL14", "METTL3", "MFAP1", "MFN1", "MFN2", "MGA", "MGAT2", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MIPEP", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO1E", "MYO5A", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "ND1", "ND4", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NF1", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCLN", "OCRL", "OFD1", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNT", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA2", "PNPLA6", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPFIBP1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI1", "RALA", "RALGAPB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RELA", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF31", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", 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"SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STIM1", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX4", "STX5", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SYMPK", "SYNE2", "TAB1", "TACC3", "TAF15", 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"results/proteins/hek293t_core/msigdb_wp/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..29e3a87532eb1ead896f4cf436144b35c25536b0 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,183 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nad biosynthetic pathways 0.8684839888705151 2.4498296147981997 0.0142923828649252 0.9998276688472622 0.2864100725292839 6 Q9NTG7,Q9UGN5,Q8IXJ6 3 +Sphingolipid metabolism in senescence 0.6320221124909806 2.2373435290440624 0.025263896302935 0.9999997958236002 0.3859803107625461 14 Q96G23,Q06136,P05771 3 +Relationship between inflammation cox2 and egfr 0.8713652737825688 2.234752986853909 0.0254335698589898 0.999999816138217 0.3859803107625461 5 P31749,Q9H7Z7 2 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.6431058992422604 2.2224704217190445 0.0262515307984407 0.9999998890911148 0.3859803107625461 12 O15460,P13674,Q96AY3 3 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8158715273950874 2.217986108735401 0.0265557795859605 0.9999999081107496 0.3859803107625461 6 P07099 1 +Striated muscle contraction pathway 0.8517204454822223 2.151133570952027 0.0314656584214829 0.9999999956223142 0.4027490563641472 5 P67936,P08670,P28289 3 +Sphingolipid metabolism overview 0.7030899279951004 2.1384766204533285 0.0324780796718771 0.9999999976675648 0.4027490563641472 9 Q06136,Q96G23,Q16739 3 +Nad metabolism 0.8429398812235654 2.1135217589975013 0.0345561346485765 0.9999999993607503 0.4027490563641472 5 Q9NTG7,Q8IXJ6 2 +Kisspeptinkisspeptin receptor system in the ovary 0.7124026626227371 2.1030891938377727 0.0354579734008302 0.9999999996358038 0.4027490563641472 8 P31751,P31749,P05771 3 +Vitamin a and carotenoid metabolism 0.8208271689656004 2.0181626989419086 0.0435743195249864 0.9999999999977508 0.4371956725673642 5 Q8WTV0,O94788 2 +Progeriaassociated lipodystrophy 0.6265663002550749 1.9633098021172155 0.0496101871759722 0.9999999999999504 0.4740528996815122 11 P09874,P02545,O60725,Q03252,O75844,P20700 6 +Ferroptosis 0.4977162961435777 1.9372349283400312 0.0527166324576018 0.9999999999999932 0.4771910032106762 24 P37268,Q15043,P09601,P45880 4 +Eicosanoid synthesis 0.9677697841726618 1.9211802690180304 0.0547089847694595 0.999999999999998 0.4771910032106762 2 Q9H7Z7 1 +Regulation of apoptosis by parathyroid hormonerelated protein 0.717081544468257 1.9196884208326288 0.0548972677192065 0.9999999999999982 0.4771910032106762 7 Q9BXK5,P31749 2 +Statin inhibition of cholesterol production 0.7981933056859851 1.9196308629861043 0.0549045427827386 0.9999999999999982 0.4771910032106762 5 P37268 1 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.5474067035280811 1.9030105951227687 0.0570391627407422 0.9999999999999996 0.4771910032106762 18 P55209,P25054,P02545,O60725,Q9Y2U8,O75844 6 +Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.7927983315198387 1.8960106312944836 0.0579586387457635 0.9999999999999998 0.4771910032106762 5 P08670 1 +Nonsmall cell lung cancer 0.5446291500637214 1.8841738994239767 0.0595414568140424 1.0 0.4771910032106762 18 P31751,P31749,P05771 3 +Familial partial lipodystrophy fpld 0.6540086737798542 1.8827070512650212 0.0597400793326585 1.0 0.4771910032106762 9 P31751,O60725,Q03252,O75844,P20700 5 +Nanomaterial induced apoptosis 0.7074419824991982 1.8732341497048308 0.0610360585502027 1.0 0.4771910032106762 7 O95831 1 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.8394070070879809 1.848441685229278 0.0645384730747069 1.0 0.4856520098871697 4 P31751,P31749 2 +Nad metabolism sirtuins and aging 0.7710253456221261 1.800178404811014 0.0718324725724999 1.0 0.5158054951063773 5 Q9NTG7,P09874,Q96EB6,Q00059 4 +Acquired partial lipodystrophy barraquersimons syndrome 0.7704493087557659 1.7976322920143464 0.0722352975250582 1.0 0.5158054951063773 5 P20700,Q03252,P02545,O60725 4 +Fluoropyrimidine activity 0.5653970063198239 1.793896566821625 0.0728296795415981 1.0 0.5158054951063773 13 P00374 1 +Allograft rejection 0.5615987962617456 1.7391591388727428 0.0820067746109152 1.0 0.5251101135200515 12 P08183,Q9BY49,P08670,P10321 4 +Apoptosis modulation and signaling 0.5133745512339492 1.728030980271943 0.0839826702548731 1.0 0.5251101135200515 19 O00273,Q13546,Q9NR28,P42575,O95831,Q9UER7 6 +Canonical and noncanonical notch signaling 0.8093366484332851 1.7230434086665711 0.0848806754112114 1.0 0.5251101135200515 4 P55081 1 +Oxidation by cytochrome p450 0.7076625222224574 1.7224404923950891 0.0849897538338111 1.0 0.5251101135200515 6 Q6UW02,O43169 2 +Kennedy pathway from sphingolipids 0.7496862788596274 1.7055072056996492 0.0880998695440617 1.0 0.5251101135200515 5 Q9HBU6 1 +Hostpathogen interaction of human coronaviruses mapk signaling 0.670918416257009 1.6954006023142674 0.0899994517465669 1.0 0.5267502736423189 7 P51812 1 +Urea cycle and related diseases 0.907625899280575 1.6724070155204265 0.0944440896515352 1.0 0.5278315188867476 2 Q9Y619 1 +Zinc homeostasis 0.9056115107913664 1.664026577769461 0.0961071182138137 1.0 0.5278315188867476 2 Q8NEW0 1 +Disorders of folate metabolism and transport 0.6633732565535393 1.6583241830773423 0.0972520504089775 1.0 0.5278315188867476 7 P00374 1 +Copper homeostasis 0.5718686805108374 1.649668333192081 0.0990107903931911 1.0 0.5278315188867476 11 P31749,P05067 2 +Histone modifications 0.5428398029014426 1.624818789612052 0.104201176197515 1.0 0.5360630168870636 12 O15047,Q9H7B4,Q03164,Q8WTS6,Q01105 5 +Onecarbon metabolism and related pathways 0.5305368741344565 1.609545292343267 0.1074971596529945 1.0 0.5380428857292335 14 Q9HBU6 1 +Ethanol effects on histone modifications 0.5385597845635064 1.598590017799612 0.1099117291917011 1.0 0.5380428857292335 12 P00374,O94788 2 +Mitochondrial complex iii assembly 0.5607401850810362 1.5848359710667244 0.1130036072598432 1.0 0.5380428857292335 11 P14927,Q6DKK2 2 +Kit receptor signaling pathway 0.4991231839501026 1.5712469085975609 0.1161253079907478 1.0 0.5380428857292335 18 P51812,Q15418,P46108,P31749,P05771 5 +Sphingolipid metabolism integrated pathway 0.5796509392555727 1.5573890874855572 0.1193781354358958 1.0 0.5380428857292335 10 Q06136,Q96G23,Q16739 3 +Bdnftrkb signaling 0.5929178900115825 1.5556051775747004 0.1198020067851746 1.0 0.5380428857292335 9 Q15418 1 +S1p receptor signal transduction 0.6048285277922696 1.5483394108127566 0.121540600502787 1.0 0.5380428857292335 8 P31749 1 +Influence of laminopathies on wnt signaling 0.5300284902342012 1.546163814972172 0.1220650100727991 1.0 0.5380428857292335 12 P49354,P25054,P02545,O60725,O75844 5 +Interactome of polycomb repressive complex 2 prc2 0.6034213120364398 1.540909823712017 0.1233387346023824 1.0 0.5380428857292335 8 Q9NYF8 1 +Nephrogenesis 0.870503597122301 1.517644176509673 0.1291041238503032 1.0 0.5508710951228505 2 O94788 1 +Thermogenesis 0.4268019335941579 1.5143397430410523 0.1299396935339614 1.0 0.5508710951228505 29 Q15418,P51812,P23786 3 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.489773771561511 1.5060552353029075 0.1320529948186328 1.0 0.5559154047609579 18 P31749,P05067,P08670 3 +Omega3 omega6 fatty acid synthesis 0.6560054753745037 1.478048845689097 0.1393947046199855 1.0 0.5761694665942277 6 Q15067 1 +Nanoparticle triggered regulated necrosis 0.8607194244604306 1.4767768947915474 0.1397354520311582 1.0 0.5761694665942277 2 P09874 1 +Mrna processing 0.3226859250987055 1.4239487030774576 0.1544613218919923 1.0 0.5977459970825618 103 Q07955,O43390,P33240,P22626,Q99729,O75400,P62995,Q8IWZ8,P38159,P49761,Q96I25,P67809,P23246,P35637,O60508,P52272,O75494,Q01130,Q15233,P52756,Q13242,P55795,O95400,O75937,Q15427,P31943,P61978 27 +Riboflavin and coq disorders 0.6160937761645122 1.4237459625427715 0.1545200233780577 1.0 0.5977459970825618 7 Q16134,Q5T2R2,Q9Y2Z9 3 +Cellular proteostasis 0.6852572806185745 1.4159057086634137 0.1568031133219258 1.0 0.5977459970825618 5 Q99471,Q9UHV9,O15212 3 +Metapathway biotransformation phase i and ii 0.432879186460982 1.4154819656923427 0.1569272323744086 1.0 0.5977459970825618 24 Q16850,Q9H0A0,Q6UW02,P21266,P21964,Q9Y2Q3,P07099,Q86UY6,Q8NCH0,P34913 10 +Mecp2 and associated rett syndrome 0.4431935044024351 1.402522713121975 0.1607592128419317 1.0 0.6048565383177681 22 P35637,P31943,Q13148,Q00013,P31749,P52597 6 +Resistin as a regulator of inflammation 0.5759893503783169 1.3954162551196396 0.162890352315983 1.0 0.6061971636487921 8 P31749 1 +Constitutive androstane receptor pathway 0.6385515529649828 1.394623286014841 0.1631294692875486 1.0 0.6061971636487921 6 P08183 1 +Egfegfr signaling pathway 0.366707903138962 1.3901617317839328 0.1644797711430536 1.0 0.6074651670436706 45 P16949,O95630,P51812,Q15418,Q9P0J0,P46108,P31749,P46934,P05771 9 +Irinotecan pathway 0.8385611510791354 1.3842065993868136 0.1662952032121443 1.0 0.6077831000913951 2 P33527 1 +Metabolism of spingolipids in er and golgi apparatus 0.7246193484886441 1.3644556044113407 0.1724242177297483 1.0 0.6157760242260083 4 Q06136 1 +Cholesterol biosynthesis with skeletal dysplasias 0.6041358312056323 1.3639119623498714 0.1725952754449906 1.0 0.6157760242260083 7 Q16850,Q15392 2 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4163452669976506 1.3565849602978706 0.1749131231605438 1.0 0.6157760242260083 27 P37268,O75845,Q16850,P48449,P35610,Q15392,Q14534,Q9BWD1,O95749 9 +Sleep regulation 0.7117677431845063 1.3096351924599734 0.1903192771091069 1.0 0.6546983132553277 4 Q99808 1 +Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.464578750654866 1.2845415150643695 0.1989525473383944 1.0 0.6691029804341533 17 Q9NTG7,Q8IXJ6 2 +Met in type 1 papillary renal cell carcinoma 0.4264906342257604 1.2713895171596976 0.2035901100924821 1.0 0.6718497278997732 22 P31751,P46108,Q92733,Q14241,P31749 5 +Cohesin complex cornelia de lange syndrome 0.4606345542368806 1.2573770455141076 0.20861713715888 1.0 0.6718497278997732 17 P25054,Q9NTI5,Q7Z5K2,Q15257,Q29RF7 5 +Estrogen receptor pathway 0.8282212795440217 1.2505322684195088 0.2111051753313497 1.0 0.6718497278997732 3 Q15067 1 +Cholesterol biosynthesis pathway 0.4730063257743252 1.239877543284216 0.2150206912121754 1.0 0.6718497278997732 14 Q16850,P37268,O75845,P48449,Q14534 5 +Erbb signaling pathway 0.4448733478654924 1.2370734297715098 0.2160598229610943 1.0 0.6718497278997732 19 P31751,P46108,P31749,P05771 4 +Oxysterols derived from cholesterol 0.5430948351618685 1.2197383311228167 0.2225640858202566 1.0 0.6718497278997732 8 P34913 1 +Caloric restriction and aging 0.6418004506905911 1.2185597110916655 0.2230113485014309 1.0 0.6718497278997732 5 Q96EB6,P31749 2 +Endothelin pathways 0.5750875546129303 1.2180475869650789 0.2232058896676987 1.0 0.6718497278997732 7 P42892 1 +Proteoglycan biosynthesis 0.6009221002951638 1.2138742291074238 0.2247957552657533 1.0 0.6732688789551419 6 Q8WVQ1,Q8NCH0 2 +Extracellular vesiclemediated signaling in recipient cells 0.6300119223116503 1.1649670382045516 0.2440323354729967 1.0 0.7144316292324352 5 P31749 1 +Endometrial cancer 0.4588115199308618 1.147975753882704 0.2509785732566758 1.0 0.7249500948536451 14 P31751,P31749 2 +Inclusion body myositis 0.8012210335942447 1.1463016839236917 0.2516703464217491 1.0 0.7249500948536451 3 P05067 1 +Apoptosis modulation by hsp70 0.586873809436489 1.1462654549830815 0.2516853319342389 1.0 0.7249500948536451 6 O95831,Q13546 2 +Mevalonate arm of cholesterol biosynthesis pathway 0.4608508322222261 1.1161976439060917 0.2643375428079555 1.0 0.7408775577816775 12 P37268 1 +Folate metabolism 0.4531009455959441 1.1110047035509705 0.2665663247217602 1.0 0.7408775577816775 14 Q8WTV0,P00374 2 +Ketogenesis and ketolysis 0.5534426463003367 1.1091846194412498 0.2673505462906598 1.0 0.7408775577816775 7 P35610,O43772,P23786,P53985 4 +Prostaglandin and leukotriene metabolism in senescence 0.7908700865113065 1.1064963529494882 0.2685117417042004 1.0 0.7408775577816775 3 P09960 1 +Small cell lung cancer 0.4516063180011718 1.1013310644192067 0.2707525958670582 1.0 0.7408775577816775 14 P31749 1 +B cell receptor signaling pathway 0.3933419287432481 1.072454996644714 0.283515717166535 1.0 0.7468312479071766 23 Q15418,P46108,P31749,P05771 4 +Melatonin metabolism and effects 0.7808355234156839 1.0680199377047466 0.2855115183268806 1.0 0.7472953653599222 3 P42892 1 +Insulin signaling 0.3373058121711871 1.0626117638168089 0.28795804998754 1.0 0.7477050181521722 45 P31751,P51812,P41440,Q6ZWJ1,Q15418,P46108,P31749,P05771 8 +Angiopoietinlike protein 8 regulatory pathway 0.3683407550716874 1.056991640198517 0.2905154027478995 1.0 0.7477050181521722 31 P31751,P51812,P41440,Q15418,P46108,P31749 6 +Sphingolipid pathway 0.4903968235869954 1.0539211860877506 0.2919190022943394 1.0 0.7478095292816695 10 Q96G23,Q06136 2 +Heme biosynthesis 0.6022288378567537 1.038933971945653 0.2988354454629909 1.0 0.7581511437035198 5 P22830 1 +Nephrotic syndrome 0.435993201817782 1.024744445347428 0.3054837857508614 1.0 0.7581511437035198 15 P02545,Q14108,Q86YH6,O75844,Q9Y2Z9 5 +1q211 copy number variation syndrome 0.4953822410245262 1.0209238957800577 0.3072904967834864 1.0 0.7581511437035198 9 Q9NPH0 1 +Interleukin11 signaling pathway 0.4373943383817041 1.0094681366295155 0.3127501753927579 1.0 0.7617859460693733 14 Q15418,Q15257 2 +Synaptic signaling pathways associated with autism spectrum disorder 0.4389945580417663 0.9800712675105464 0.3270509408879305 1.0 0.7617859460693733 12 P31749 1 +Regulatory circuits of the stat3 signaling pathway 0.4384159176397468 0.976478347664386 0.3288274726657647 1.0 0.7617859460693733 12 P16949,Q8WTS6,P05771 3 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.5228267620965606 0.955692429013176 0.3392276486499135 1.0 0.7623649228070188 7 P06753,P04150 2 +Electron transport chain oxphos system in mitochondria 0.3176376340905382 0.9453950255431284 0.3444572408696165 1.0 0.7623649228070188 53 Q9UII2,O75964,O43676,P06576,O95169,P00846,P14927,P14406,P22695,P13073,O96000 11 +Mitochondrial complex iv assembly 0.4481446938036245 0.9194632631089052 0.3578533124719172 1.0 0.7715002097288292 11 P14406,Q9Y2R0 2 +Apoptosis 0.3996697206169586 0.9101134937946176 0.3627626589614636 1.0 0.7715002097288292 19 O00273,Q13546,Q9NR28,P42575,P31749 5 +Primary focal segmental glomerulosclerosis fsgs 0.3935260077684327 0.9084724830389376 0.3636286455345687 1.0 0.7715002097288292 20 P31749,P08670 2 +T cell receptor and costimulatory signaling 0.5132680209534926 0.908061050300362 0.3638459674942007 1.0 0.7715002097288292 7 P31749 1 +Vitamin d receptor pathway 0.4243517537155946 0.905977119998132 0.3649479628363115 1.0 0.7715002097288292 13 P08183 1 +Melanoma 0.409419967016317 0.905020529103458 0.3654545114975693 1.0 0.7715002097288292 17 P31751,P31749 2 +Somatroph axis gh and its relationship to dietary restriction and aging 0.736643334836655 0.9004747474832779 0.3678676580643694 1.0 0.7715002097288292 3 P31749 1 +Onecarbon metabolism 0.4165595486167886 0.8756003474549672 0.3812473364544455 1.0 0.7715002097288292 14 P00374 1 +Pathways of nucleic acid metabolism and innate immune sensing 0.6085649915069298 0.8723759150881695 0.383003335308659 1.0 0.7715002097288292 4 Q9Y3Z3 1 +Cytosine methylation 0.564735497312555 0.8704911068711715 0.3840320771103576 1.0 0.7715002097288292 5 P48735 1 +Epo receptor signaling 0.4758669689098289 0.8614397318190007 0.3889959011800332 1.0 0.7715002097288292 8 P31749 1 +Egfr tyrosine kinase inhibitor resistance 0.4020900124372837 0.8550787044599616 0.3925075780329701 1.0 0.7715002097288292 17 P31749,P05771 2 +Glioblastoma signaling pathways 0.3724364760221679 0.8467861735223587 0.3971143162964528 1.0 0.7715002097288292 22 P31751,P31749,P05771 3 +Epithelial to mesenchymal transition in colorectal cancer 0.3617830530566067 0.8315027520705273 0.4056896741898534 1.0 0.7715002097288292 24 P31751,P31749,Q16625 3 +16p112 distal deletion syndrome 0.4683561078614318 0.8219784177989158 0.4110891802525291 1.0 0.7715002097288292 8 Q9H2V7,Q8NCF5 2 +Wntbetacatenin signaling pathway in leukemia 0.5185620470517082 0.8201027035065658 0.4121575611700132 1.0 0.7715002097288292 6 P31749 1 +Translation inhibitors in chronically activated pdgfra cells 0.3743945464811413 0.8119804492902081 0.4168028499032437 1.0 0.7715002097288292 21 Q15118,P31751,P23588,Q15418,P31749 5 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.512127388453669 0.7899142797812118 0.429577831278036 1.0 0.7715002097288292 6 P31749 1 +Tlr4 signaling and tolerance 0.5852265497905491 0.7761812438567982 0.4376419789232195 1.0 0.7794688500348467 4 Q15629 1 +Fas ligand pathway and stress induction of heat shock proteins 0.3887868695206863 0.7651660505415739 0.4441726727478281 1.0 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0.5079639719635334 1.0 0.8287108702494501 15 O43772,P23786 2 +3q29 copy number variation syndrome 0.3817559659568528 0.6567383611089386 0.5113491638366927 1.0 0.8297363790557656 14 O95684 1 +7oxoc and 7betahc pathways 0.418038972636207 0.6521534921497769 0.5143021589151631 1.0 0.8322846765240004 10 P34913,O14734 2 +Orexin receptor pathway 0.3621331079080843 0.61476406530229 0.5387105438936903 1.0 0.8495377363113177 18 Q15118,O60313,P11166,Q9H4L5,Q00059,Q13595 6 +Nrp1triggered signaling pathways in pancreatic cancer 0.3769276057942889 0.6035672351141186 0.5461314019144186 1.0 0.8495377363113177 12 P31749 1 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.3722597659849009 0.5987326664154621 0.5493511699383133 1.0 0.8506467913095671 14 Q15118,P31749 2 +Tcell receptor tcr signaling pathway 0.3487320530972142 0.5849495045809529 0.5585816703181434 1.0 0.8534674252069095 20 P46108,P31749,P08670 3 +Il5 signaling pathway 0.3654443625291144 0.5462961632567019 0.5848623731733587 1.0 0.8714813247275479 13 Q15418 1 +Adipogenesis 0.3583241788417051 0.5442120282632738 0.5862955756057424 1.0 0.8714813247275479 16 P02545,P17096,P04150,P14174,O75844,P43490 6 +Osteoblast differentiation and related diseases 0.3657143647105882 0.5388528107635964 0.5899884203574317 1.0 0.8723330759989252 12 P05771 1 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.3611885385052561 0.5324160520485882 0.5944378699548623 1.0 0.8749427816939538 14 P31751,P31749 2 +Chemokine signaling pathway 0.3142070761962236 0.5226983031306637 0.6011842192858616 1.0 0.8770664559714131 29 P31751,P31749,P05771 3 +Embryonic stem cell pluripotency pathways 0.361029893494622 0.5206819103518766 0.6025883780825969 1.0 0.8770664559714131 13 P31751,P31749 2 +Atm signaling pathway 0.3513166683879189 0.5011003385914702 0.6163005085683277 1.0 0.8875906845888356 16 P42575,Q9BXW9,Q13546,P16104 4 +Lung fibrosis 0.4458005122886334 0.4912805312698179 0.6232280476967849 1.0 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0.7289858713091217 1.0 0.9435135910396004 12 P31751,P31749 2 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.3437237090862457 0.3445527410263896 0.7304306396032965 1.0 0.9435135910396004 11 Q15118,P31749 2 +Tryptophan metabolism 0.3250843380302004 0.3372952722407522 0.7358943233142001 1.0 0.9435135910396004 15 O94788 1 +Nonhomologous end joining 0.4331236901205085 0.3324987325126246 0.7395126966247851 1.0 0.9435135910396004 5 P12956 1 +Mitochondrial immune response to sarscov2 0.3543517254168337 0.3320775435310383 0.7398307065385914 1.0 0.9435135910396004 10 Q7Z434,Q9Y375,Q86UT6 3 +Notch signaling 0.3530764711692968 0.326264182741096 0.7442244848322199 1.0 0.9435135910396004 10 Q92830 1 +Neural crest differentiation 0.3389836119923934 0.321803845921271 0.7476013005413447 1.0 0.9435135910396004 11 Q9NR77 1 +Dna irdouble strand breaks and cellular response via atm 0.2933589771260053 0.3136011062830723 0.7538240192073402 1.0 0.9456875401241314 25 P09874,P16104 2 +Ranklrank signaling pathway 0.3069616088141004 0.289015818672133 0.7725692723345374 1.0 0.9510975499905756 19 P31751,P31749,Q13501 3 +Tgfbeta receptor signaling 0.3883607029674396 0.2652282854996061 0.7908336062634054 1.0 0.9625103643941948 6 P27361,P62942,P42224,Q92793,P40763 5 +Tgfbeta receptor signaling in skeletal dysplasias 0.3883607029674396 0.2652282854996061 0.7908336062634054 1.0 0.9625103643941948 6 P27361,P62942,P42224,Q92793,P40763 5 +Retinoblastoma gene in cancer 0.2588831589699591 0.2644503207020129 0.7914329408224692 1.0 0.9625103643941948 51 P33991,P00374,Q9Y619,Q14566,Q16204 5 +Glycosaminoglycan degradation 0.3824282056837452 0.2444752561230742 0.8068627634052417 1.0 0.9656687546122376 6 P06865,P16278 2 +Complement system 0.3449910077289217 0.239514473833791 0.8107066745386855 1.0 0.9664265704401755 8 P26885 1 +Rac1pak1p38mmp2 pathway 0.2936838797682041 0.2306519320312577 0.8175852192703603 1.0 0.9707816607509998 20 P46108,P31749 2 +Hedgehog signaling pathway wp47 0.5096402877697801 0.2060962830239035 0.836715702166541 1.0 0.979018899633454 2 O00422 1 +Dna repair pathways full network 0.2493592046147908 0.1750057543864556 0.8610751120201192 1.0 0.9949466745414812 53 P09874,Q9UQ84,P41440,P16104,P12956,Q9UGN5,P41208 7 +Il18 signaling pathway 0.2401943986487607 0.1703700178327669 0.8647191497134468 1.0 0.9960945892081714 65 P16949,P09874,Q13011,Q9UMR5,Q03252,Q8N6H7,Q92733,Q8N6T3,P51858,P09601,P05771 11 +Cardiac hypertrophic response 0.292107582080564 0.168874756093644 0.865895155708917 1.0 0.9960945892081714 13 P31749 1 +Hostpathogen interaction of human coronaviruses interferon induction 0.3586862575626643 0.1674290113700225 0.8670324995765479 1.0 0.9960945892081714 6 Q13546,P19525,O15111,Q7Z434,P42224 5 +Proteasome degradation 0.2534017538496146 0.1611838312514404 0.871948615396887 1.0 0.9998344123217636 43 O00233,P16104,P28070,O00231,Q9UL46,P10321,P04439,P61289,P49721,P46934 10 +Microrna network associated with chronic lymphocytic leukemia 0.4722302158273335 0.1347998535779588 0.8927701216091164 1.0 1.0 2 Q07820 1 +Gastric cancer network 1 0.2806933219942155 0.1240838623925074 0.9012488753515636 1.0 1.0 12 P33991,Q9ULW0,P25054 3 +Mammary gland development pathway involution stage 4 of 4 0.4723661485319385 0.1224164946922962 0.9025691758822916 1.0 1.0 3 Q07812,P40763 2 +Integrinmediated cell adhesion 0.2636715611187587 0.1204446109054177 0.9041309542027034 1.0 1.0 24 P31751,P31749 2 +Tnfalpha signaling pathway 0.2617612813589886 0.1096954404596243 0.9126509165807424 1.0 1.0 24 Q9NR28 1 +Type ii diabetes mellitus 0.3789231212208398 0.1073562255477613 0.9145063806913294 1.0 1.0 4 Q05655,P28482,O00330 3 +Il4 signaling pathway 0.2758553207572988 0.1062280230204924 0.9154014375785662 1.0 1.0 12 P31749 1 +Myometrial relaxation and contraction pathways 0.260949085281342 0.1054328915880022 0.9160323177887806 1.0 1.0 23 P05771,P0DP25 2 +Notch signaling pathway 0.2672535672280563 0.0712110526234262 0.9432297850289852 1.0 1.0 15 P31749 1 +Intracellular trafficking proteins involved in cmt neuropathy 0.2858554935708085 0.0710736151993527 0.943339167073173 1.0 1.0 10 Q9NR77,Q6UWE0 2 +Head and neck squamous cell carcinoma 0.2634518630849559 0.0590858169358662 0.9528837553502184 1.0 1.0 17 P31751,P31749 2 +Hepatitis b infection 0.2494185078683008 0.044290762739648 0.964672634716524 1.0 1.0 26 P31749,P05771 2 +Purinergic signaling 0.3902158273381249 0.0438489077186043 0.965024841827362 1.0 1.0 2 P08754 1 +Atr signaling 0.3893525179856065 0.043302941943755 0.9654600460919768 1.0 1.0 2 Q92547 1 +Mammalian disorder of sexual development 0.3879136690647437 0.0424087515146827 0.9661728519273708 1.0 1.0 2 Q14781 1 +Circadian rhythm genes 0.2368982528146409 0.0422025960695967 0.9663371930416152 1.0 1.0 45 P29375,Q9Y2W1,P00813,P23246,Q8N163,Q03164,Q9BWF3,Q9NRV9,P54802,Q14103,Q8WXF1,Q96EB6,Q15233,P43490 14 +Type i interferon induction and signaling during sarscov2 infection 0.4001151410477728 0.0356711812481701 0.9715445499541776 1.0 1.0 3 Q7Z434,P42224 2 +Atm signaling in development and disease 0.2494468302884239 0.0333743876019178 0.973376034014206 1.0 1.0 22 O75150,P16104,Q15257 3 +Glucocorticoid receptor pathway 0.2701279884967246 0.0155797198036931 0.9875696849725984 1.0 1.0 8 P04150 1 +Monoamine transport 0.3583765112262396 0.0104258488995601 0.9916815268307342 1.0 1.0 3 O14795,O15127 2 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..02c733914f7b7ea283e9208c46db59f0a19d3079 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Srf and mirs in smooth muscle differentiation and proliferation", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APC", "APEX1", "APEX2", "APMAP", "APP", "APPL1", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARMC8", "ARMC9", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG9A", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "B9D1", "BAG2", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLVRA", "BPTF", "BRCA1", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "C21orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CASP2", "CASP3", "CASP7", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CEBPZ", "CENPB", "CENPE", "CENPF", "CEP170", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHKA", "CHMP5", "CHMP6", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLK3", "CLPTM1L", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ6", "COQ8A", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEGS1", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB4", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "ELP4", "EMD", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERI1", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIS1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTH1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GABPA", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GCC2", "GCDH", "GCLC", "GCLM", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GIT1", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN5", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT2A", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGALS3BP", "LIG3", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRFIP1", "LRSAM1", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LUC7L", "LYN", "LYRM7", "LZTFL1", "MACF1", "MAD2L1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "METTL3", "MFAP1", "MFN2", "MGA", "MGAT2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MKLN1", "MMAB", "MOGS", "MORC3", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA20", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND1", "ND4", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NF1", "NFATC2IP", "NFKBIE", "NIPBL", "NKRF", "NLRX1", "NME1", "NME2", "NME3", "NONO", "NOP2", "NOTCH2", "NPC1", "NPC2", "NR3C1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OFD1", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OSBPL3", "OTUD7B", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNT", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PIBF1", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMAIP1", "PMPCA", "PMVK", "PNP", "PNPLA2", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN9", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB3B", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABAC1", "RABGAP1", "RABGEF1", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RB1", "RBBP4", "RBBP7", "RBL1", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNF14", "RNF2", "RNF20", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RTCB", "RTN3", "RTN4", "RUVBL1", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SASS6", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC14L2", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SELENBP1", "SELENOF", "SEPT11", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR3", "SSR4", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STIM1", "STIM2", "STIP1", "STK4", "STMN1", "STRAP", "STRN", "STUB1", "STX4", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TAF6", "TALDO1", "TAOK1", "TAOK2", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCP1", "TDP1", "TECR", "TEDC1", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TLN1", "TM7SF2", "TMED10", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRRAP", "TSC22D3", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC26", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TXNDC15", "TXNDC5", "TXNL4A", "TXNRD1", "TYMS", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2J2", "UBE2L3", "UBE2N", "UBE2V1", "UBE3A", "UBIAD1", "UBR2", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC13B", "UNG", "UPF1", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS11", "VPS16", "VPS18", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASL", "WDHD1", "WDR1", "WDR26", "WDR34", "WDR5", "WDR73", "WDR74", "WFS1", "WIPI2", "WNK1", "WRN", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ADA", "AIFM1", "AKT1", "AKT2", "ALDH1A2", "APC", "APP", "ARFGAP1", "ARFGAP2", "ATP5B", "ATP5L", "ATP6", "ATPIF1", "BAX", "BCL2L13", "BCLAF1", "CALM3", "CANT1", "CASP2", "CBX2", "CCAR2", "CCDC6", "CD2BP2", "CDC40", "CDK4", "CDK6", "CDKN2A", "CERS2", "CETN2", "CHRAC1", "CHST14", "CHUK", "CLK3", 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new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f7561038c3ec640182e0e383dcef33da7ea4728d --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "nuclear_punctae", "1": "nucleolus_fc_dfc", "2": "nuclear_membrane"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2709052b84a0503e4ece052c06c13dd8000958ce --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid 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b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a1ee8858ca0ef4f9c91f0c327cd15f42a0d00023 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a696039960cd17139e923030d2199af5006e61ac9b30b02f81e35384cacecf3b +size 76574 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ad21af449b7dd999c36ceaee3e8682a1a3afe322 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 105.29411764705883 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3d58f4ef7e4ba3634db710377f95bf694cd7c350 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..68ad7179e56ee7c532a0f3100a57f2e8d6070aaf --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +mitochondria 0.5737797019249872 1.6607698280726666 0.0967596830406107 0.8227213865996532 1.0 11 P21796,Q8IWA4,Q9Y277,P45880 4 +nuclear_punctae 0.3307187629825824 1.447996265737061 0.1476180949578469 0.9338116175354748 1.0 87 O75150,Q9ULX6,Q13501,Q13148,Q8IXT5,P98179,P38159,Q9HD42,Q96PK6,Q9NPJ6,Q16637,P23246,Q01844,P78332,Q15233,P19388,O95400,P38432,Q8WXF1 19 +nucleolus_fc_dfc 0.346002266273328 0.7179842778071868 0.4727669809945132 0.9999812049183496 1.0 25 P19388,Q01844,O95429,P78332,Q96PK6,Q15233,Q8IXT5 7 +nuclear_membrane 0.2476896174565978 0.047533810567672 0.9620877838451138 1.0 1.0 30 P49790,P02545,P49792,P35658,Q9Y2U8,P57740,P52292,P42166,P52948,P20700 10 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9ebc1eb243ff36f78993c979d7e8d6d3974583a4 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", 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b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 159, + "title": "Average number of proteins per term", + "value": 14.817610062893081 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0378002ac7e8dfde9aa68380d69d2abb8addba99 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5aef35b5e909ff1be6ad301c69d1af7a2e5bdfc9 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,58 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +protein modifying enzyme 0.6801865646174425 3.278208765429563 0.0010446810243034 0.1531156262445873 0.0452742016446938 24 P51812,Q15418,Q9UMR5,O60725,O15460,Q92791,Q6P2P2,P13674,P50897 9 +metalloprotease 0.6310265779099699 3.025428720532263 0.0024828091887447 0.3264934371804176 0.0452742016446938 26 P55786,O95630,Q9NZ08,O75844,P42892,Q5JRX3,Q9UIQ6,Q9BYT8,P22695,Q7Z2K6,Q10713 11 +oxygenase 0.840745090970788 2.7251512642335816 0.0064272033844843 0.641283730583869 0.0851604448444173 8 P30519,Q6UW02,P09601,Q9BV57,Q9Y2Z9 5 +RNA splicing factor 0.4155574569709467 2.656294292510827 0.007900463490098 0.7166754344174192 0.0966287457635075 86 Q07955,O75940,Q9UHX1,Q9UBB9,Q9P2K5,Q8IXT5,Q15459,O95391,Q96PU8,P62310,O75934,Q52LJ0,Q8IWZ8,Q9Y3B4,Q96PK6,P31942,Q96I25,Q15020,Q16637,O60508,P52272,O75494,Q12874,O75525,Q01130,Q86UA1,P52597,Q15637,Q8WXF0,Q12849,Q13242,P55795,Q9BWF3,Q8WWY3,P62312,O95400,Q15427,P31943,Q07666 39 +secondary carrier transporter 0.666878033140395 2.546066969177234 0.0108944285553986 0.8247810559401385 0.1226417101979892 16 Q9UJS0,O00400,Q15043,Q9BQT8,Q9Y5Y0 5 +transmembrane signal receptor 0.8388889962739505 2.4878702692926353 0.0128510601448601 0.8721070314225595 0.1277074101895477 7 Q99720,Q8WUJ1,Q9UMX5,O15173 4 +transporter 0.42697214250166 2.3609655849899345 0.0182274220570981 0.9463298615966672 0.1514327253322645 58 Q99595,O60830,Q9NR77,Q567V2,Q15070,Q9Y619,P41440,Q99808,O43681,Q8NFH4,P37198,Q99567,Q99805,O43615,Q8N1F7,O43772,Q9H2V7,P53985,P57740,Q9HD45 20 +calmodulin-related 0.6347826991293705 2.212073565452636 0.0269615822941267 0.9870381194636564 0.1767719172741568 13 O43852,Q14257,Q02818,P0DP25,Q9BRK5,P80303,P41208,Q8IYU8 8 +esterase 0.7004938479023788 2.04310414482657 0.0410421297071461 0.9987231939768793 0.2356529301342278 8 Q8IY17,Q9NUJ1,Q969T7 3 +nucleic acid metabolism protein 0.7537446134314374 1.9364387237316056 0.0528139906101725 0.9998208533631362 0.2895663623109461 6 P49750,Q9Y2W1,Q9NYF8 3 +mitochondrial carrier protein 0.6931308736159477 1.8038890522108004 0.071248701562963 0.9999921293609622 0.343289198439731 7 Q70HW3 1 +hydrolase 0.4560123793992823 1.579019979801341 0.1143314743238665 0.9999999958683587 0.4177234738056236 23 Q9BQG2,P07099,P34913 3 +serine protease 0.5075576951395282 1.5786408712104976 0.1144184543565964 0.999999995932377 0.4177234738056236 17 Q9H3G5,Q4J6C6,P42785,P67812 4 +membrane trafficking regulatory protein 0.4554606013914247 1.498357596336251 0.1340403671825873 0.9999999998846212 0.4440087162923207 22 P24390,Q14108,Q96EA4,Q8WTV0,Q9P253 5 +lyase 0.5426953468814324 1.4790918571711975 0.1391157662049758 0.9999999999546876 0.4463914841067461 11 P22830,Q9UHG3 2 +protein-binding activity modulator 0.747068598275971 1.460049238082355 0.1442765421644256 0.9999999999825812 0.4463914841067461 4 O14737 1 +ATP synthase 0.4475178409978926 1.4363594170996803 0.1509000948086627 0.9999999999949364 0.4463914841067461 22 Q15904,O75964,P06576,P00846,Q93050,O75947 6 +primary active transporter 0.4268621496745792 1.417223804939637 0.1564175040435107 0.999999999998204 0.4463914841067461 26 Q6NTF9,O75381,P35670,P16615,Q9NS69,O60888,Q6P4A7,Q9H2J7,Q8N4H5,P98194,Q96NB2 11 +voltage-gated ion channel 0.8667242371905532 1.3996389750187417 0.1616214565022136 0.9999999999993286 0.4463914841067461 3 P21796,P45880 2 +chromatin/chromatin-binding, or -regulatory protein 0.3576665943834978 1.398170263623679 0.1620619441306554 0.9999999999993824 0.4463914841067461 51 Q8N163,P39687,Q29RF7,O75376,Q9NTI5,Q8WVM7,Q01105,Q13111,P55209,Q9NY61,Q9UPN9,O00422,O15164,Q9UBU8,Q9BTT0,Q6PL18,Q86U86,Q969G3,Q9NPI1,Q99733,Q92922,Q8IXK0 22 +apolipoprotein 0.8316546762589916 1.355367294099442 0.1753005644878755 0.9999999999999508 0.4463914841067461 2 Q9BQE5 1 +decarboxylase 0.6689041684076694 1.341742224452761 0.1796795910869921 0.9999999999999788 0.4463914841067461 5 Q8NBZ7 1 +tubulin 0.6570109046895831 1.287713168972308 0.1978458277201431 0.9999999999999994 0.4695147254851158 5 P07437,P68371 2 +nucleotide phosphatase 0.5560475395460847 1.1222814269792796 0.2617428005563522 1.0 0.566479098500392 7 Q9H857,Q8WVQ1,P49902 3 +viral or transposable element protein 0.6648375093305261 1.1095172155424666 0.2672071219341472 1.0 0.566479098500392 4 Q9UN81 1 +transcription cofactor 0.4412574962417923 1.0879987119132144 0.276595676175799 1.0 0.5786672698941059 16 Q9Y3E1,Q7Z4V5,Q86U70,P51858,Q9HCD5 5 +oxidase 0.4207824318415682 0.950491419146318 0.3418626119344079 1.0 0.6496329133213204 16 P13073,P36551,P14406 3 +RNA metabolism protein 0.2949286906044892 0.9371158497849646 0.3486989693197762 1.0 0.6496329133213204 96 O60506,Q5T3I0,Q96BK5,O43390,Q9H814,Q9NYH9,Q8IY67,Q9Y520,Q86V81,Q9UPR3,Q8IWX8,Q5JSZ5,Q71RC2,Q9BVJ6,Q9UHB9,P23246,Q01844,P35637,Q96AE4,Q92804,Q15233,Q92945,Q9BVI4,O00566,Q96I24,Q8WXF1,P61978 27 +ATP-binding cassette (ABC) transporter 0.4795650365356829 0.9343512132895078 0.3501227547870935 1.0 0.6496329133213204 9 P08183 1 +amino acid transporter 0.6228275315314068 0.9319279208909826 0.3513737770165632 1.0 0.6496329133213204 4 P30825 1 +DNA metabolism protein 0.3324011701489632 0.9000254528437919 0.3681067055960616 1.0 0.6651018885201568 40 P33991,P09874,Q04837,Q96SB8,Q14566,P38432,Q9UGN5,Q9BQ61 8 +acyltransferase 0.3756940364884721 0.8721452328396426 0.3831291525776803 1.0 0.6844666883129346 22 Q6UWP7,P35610,O15228,Q9HCL2,P23786,P49356,Q8NCC3 7 +SNARE protein 0.4137512881923963 0.8395392372922673 0.4011667804597709 1.0 0.708727978812262 13 O60499,Q9NV70,Q5SQN1,O95721,Q9P2W9 5 +C2H2 zinc finger transcription factor 0.4461558306052116 0.7538527911803663 0.4509376205328501 1.0 0.7627561879225869 9 P17028,Q7Z3K3,Q9Y467,O95785,Q8ND82 5 +translation factor 0.4758175311976434 0.7240727434480141 0.4690210770862246 1.0 0.7768161589240596 7 P51116,P51114,Q53EL6 3 +microtubule binding motor protein 0.3402418955048399 0.6475911896648324 0.5172493971598799 1.0 0.814283704439811 23 Q13561,O95235,O75935,Q86Y91,Q92845,Q9H0B6 6 +phospholipase 0.4568052925085819 0.6331172697754538 0.526657065425284 1.0 0.8166809356316032 7 Q8NHP8 1 +endodeoxyribonuclease 0.636546762589925 0.5786606098093597 0.5628181994720913 1.0 0.8363373244491825 2 P17096 1 +aspartic protease 0.623547187328736 0.5011947641886703 0.6162340587928645 1.0 0.8647577848103425 3 Q8TCT9 1 +phosphatase 0.3430482941228964 0.4899019883168177 0.624203255992047 1.0 0.8647577848103425 18 Q9H773 1 +major histocompatibility complex protein 0.6172065353589009 0.4808783812767916 0.6306029385315381 1.0 0.8647577848103425 3 P10321 1 +damaged DNA-binding protein 0.6018497794130704 0.4329373763307656 0.6650602656710025 1.0 0.8955463511687841 3 P54725 1 +oxidoreductase 0.2687291461580888 0.3583142748714454 0.7201081365616027 1.0 0.9303810831055964 47 O43676,O95169,Q15067,O95831,O43169,Q8N4Q0 6 +kinase inhibitor 0.5739781232009072 0.3510108403986985 0.725580215755308 1.0 0.9303810831055964 3 Q9NQG5,Q5VT52 2 +kinase 0.2989998545013542 0.3422180014783219 0.7321868389864987 1.0 0.9313416591908265 23 Q9HA64,Q9BRR6,Q9HBU6,P42356,Q8TBX8,P35790,Q9BTU6 7 +general transcription factor 0.2772896773904661 0.275516230293646 0.7829196581853106 1.0 0.9496605425561276 32 P53999,Q9NPJ6,Q00403 3 +transfer/carrier protein 0.3115022304991258 0.2545866671635268 0.7990423580082457 1.0 0.9496605425561276 12 O75521 1 +glycosidase 0.4092837914718507 0.2529034192303188 0.8003428471856673 1.0 0.9496605425561276 5 Q9BTY2 1 +structural protein 0.5102158273381254 0.207346323836199 0.8357393989449884 1.0 0.9699457257828696 2 Q9UPM9 1 +tight junction 0.5015827338129453 0.1890792161316998 0.85003073078374 1.0 0.9727202631655816 2 Q9UDY2 1 +kinase modulator 0.3842165898617565 0.178419690483316 0.8583933866290954 1.0 0.9727202631655816 5 P54619,P10644,P13861,P67870 4 +mRNA polyadenylation factor 0.3163230495336483 0.1730641700533834 0.8626009880902328 1.0 0.9727202631655816 10 Q9UNK9,O95453 2 +membrane traffic protein 0.2370579163057668 0.1318098463625617 0.8951346982377268 1.0 0.980146684588911 77 Q96ED9,Q9NX40,Q99523,Q96D71,Q9H444,P43307,P40855,Q08379,Q9HD42,Q96PC5,Q13432,A6NIH7,Q12768 13 +zinc finger transcription factor 0.3079624605545718 0.1256500971964895 0.9000089053457925 1.0 0.980146684588911 9 Q9H1B7,O94880,Q7Z5J4,Q9UBW7,Q7Z5L9 5 +phosphatase modulator 0.350230414746546 0.094577082871647 0.9246507534438168 1.0 0.9867078509903816 5 Q96QC0,P30154,Q5H9R7,Q8TF05 4 +DNA-binding transcription factor 0.2607098755304596 0.0633879138212237 0.9494576112704176 1.0 1.0 20 O15226,Q32MZ4,Q9NXV6,Q96JN0,Q9NRG0,Q00577 6 +histone modifying enzyme 0.2599521150855418 0.0453139730121334 0.963857050026157 1.0 1.0 16 O15047,P29375,Q9H7B4,Q03164,Q9UBL3,Q8WTS6 6 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a02ac330ae7d79e9ac8ecb11278f9d5eb425dc85 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "storage protein", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMFR", "AMPD2", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKRD17", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APEH", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGAP18", "ARHGDIA", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6IP5", "ARMC9", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATF7IP", "ATG3", "ATG4B", "ATL2", "ATM", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BAG2", "BAG6", "BAIAP2", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD7", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CAST", "CBL", "CBR1", "CCAR1", "CCAR2", "CCDC94", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC7", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CEP170", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHERP", "CHKA", "CHM", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COA3", "COASY", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ6", "CORO1B", "CORO1C", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSGALNACT2", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLVCR1", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSD1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GINS2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLT1B", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK1", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LCMT1", "LCOR", "LDAH", "LDB1", "LDHA", "LDHB", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRFIP1", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLAL1", "LYRM7", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED23", "MED24", "MED4", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFAP1", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MLLT1", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTSS1L", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA20", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "NCOR1", "ND1", "ND4", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NENF", "NF1", "NFKBIE", "NFS1", "NGDN", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF14", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTAR1", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RAC3", "RACGAP1", "RAD18", "RAD23A", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP6", "RBL1", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP4", "REEP5", "RELA", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNF2", "RNF31", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "S100A11", "SAAL1", "SACM1L", "SAE1", "SALL2", "SAMHD1", "SAP18", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", 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b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 2178, + "title": "Average number of proteins per term", + "value": 3.1561065197428833 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8823e94fd12f4e3664ecb8d6e5c9533a0d8cb0ce --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ef7929b1e3b941c4c5ff3a5731f5373100705ac2 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,82 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +SLC superfamily of solute carriers 0.669923403180498 4.40356953536765 1.064841317899301e-05 0.0229254915744651 0.0115961219519244 46 O43772,Q9UJS0,O00400,P41440,Q9Y619,Q99808,Q15043,Q70HW3,P30825,Q8IXU6,P53985,Q9BQT8,Q9Y5Y0,Q8NEW0,Q9BSK2,Q96NB2 16 +mRNA splicing factor 0.5183002622386417 3.781212061191943 0.0001560666598052 0.2881867650006043 0.0346139299504938 67 Q07955,P33240,P19338,Q9UBB9,Q8IY67,Q13595,P98179,Q14011,Q96PU8,Q15459,O95391,P62310,P62995,Q8IWZ8,P38159,Q96PK6,P23246,Q01844,P35637,O60508,Q96E39,O75494,O75525,Q01130,Q92804,Q15233,Q86UA1,Q15637,Q8WXF0,Q13242,P62312,Q8WXF1,Q07666 33 +mRNA processing factor 0.4413913293177458 2.97981272938543 0.0028842465270488 0.9981470302399684 0.0346139299504938 83 Q07955,P33240,P19338,Q9UBB9,Q8IY67,Q13595,P98179,Q14011,Q15459,O95391,Q96PU8,P62310,P62995,Q8IWZ8,P38159,Q96PK6,Q96I25,P23246,Q01844,P35637,O60508,Q96E39,O75494,O75525,Q01130,Q92804,Q15233,Q86UA1,Q15637,Q8WXF0,Q13242,O95453,P62312,Q8WXF1,Q07666 35 +Metalloprotease 0.5401738208101153 2.8613307166110373 0.0042186672965498 0.99989973492747 0.034635821974846 37 P55786,O95630,O43847,Q9NZ08,O75844,P42892,Q5JRX3,Q9UIQ6,Q9BYT8,P22695,Q7Z2K6,Q10713 12 +AGC group 0.7642694738473319 2.710390560863374 0.006720402222418 0.9999995814380364 0.0377243196918211 11 Q15418,P31749,P51812,P05771 4 +Phosphatase modulator 0.80378666863988 2.641750486450052 0.0082478792962148 0.9999999853433686 0.0405505216865822 9 P55209,Q15257,Q01105 3 +Serine protease 0.5642812109593531 2.618833183043125 0.0088231082256029 0.9999999958576696 0.0417437993958426 28 Q9H3G5,P67812,Q9HB40,Q96AE4,Q96I24,P34913,P42785,Q92945 8 +Signaling 0.6250041424444747 2.56744022371754 0.0102452452052284 0.9999999998184042 0.0446525514785271 20 O75475,O15173,Q9Y3E1,Q99627,Q13123,Q7Z4V5,P42166,Q8WUJ1,P51858,Q96PC5,O00264 11 +Protease 0.3725750259342177 2.4990418213250165 0.0124529613981412 0.9999999999985976 0.0490462023962958 120 P67812,O43847,P42892,Q5JRX3,Q9BYT8,Q86UT6,Q7Z2K6,Q92905,P34913,Q10713,P55786,O95630,Q9HB40,P22695,Q8TCT9,Q9Y4P1,Q01804,Q9UIQ6,Q8NHP8,Q96AE4,P42785,Q92945,Q9H3G5,Q96RU2,Q96I24,P61978,O75844,Q9NZ08 28 +Epigenetic regulator 0.4961722564273292 2.387430312743103 0.0169666190556874 1.0 0.0581026671435333 34 P45973,Q16637,Q86X55,Q6PL18,Q13185,Q8IXJ6,O96028,Q9H7B4,Q14781,O60885,Q9NPI1,Q12888,Q9NTG7,Q96L73,Q96EB6,Q8WTS6 16 +Calmodulin 0.6373711278731509 2.315564143892735 0.0205820784978503 1.0 0.0651566380353459 15 O43852,Q14257,Q02818,P0DP25,Q9BRK5,Q8N163,P80303,P41208,Q8IYU8 9 +Intracellular calcium-sensing protein 0.6373711278731509 2.315564143892735 0.0205820784978503 1.0 0.0651566380353459 15 O43852,Q14257,Q02818,P0DP25,Q9BRK5,Q8N163,P80303,P41208,Q8IYU8 9 +SLC25 family of mitochondrial transporters 0.5845333223337227 2.293530096331017 0.021817504694535 1.0 0.0672251011207824 20 O43772,Q9UJS0,Q9Y619,Q70HW3,Q9BQT8 5 +Calcium-binding protein 0.59097798934981 2.2625023207677963 0.0236663856151668 1.0 0.070119677210663 19 O43852,Q14257,Q02818,Q9BRK5,P0DP25,Q8N163,P80303,P43307,P41208,Q8IYU8 10 +Phosphatase inhibitor 0.780393849990256 2.219447081248311 0.0264563236263242 1.0 0.0750284802840288 7 P55209,Q01105 2 +Growth factor 0.7710799037706032 2.015829487130153 0.0438178090153829 1.0 0.1049892057596303 6 Q7Z4V5,Q9Y3E1,Q96PC5,P51858 4 +Reader 0.5882526657096245 2.0127885541460877 0.0441368785513287 1.0 0.1054843671246612 15 Q6PL18,Q16637,Q13185,P45973,P51608,O60885,Q86U86,Q14781,Q9NPI1,Q12888,Q8WWQ0 11 +Eraser 0.6933309154423577 2.0068425904832785 0.0447664262982772 1.0 0.1064424415694844 8 Q8IXJ6 1 +RSK subfamily 0.9792805755395684 1.968407005521582 0.0490212264909422 1.0 0.1128760395630336 2 P51812 1 +RSK family 0.9792805755395684 1.968407005521582 0.0490212264909422 1.0 0.1128760395630336 2 P51812 1 +Histone deacetylase 0.8040960058961233 1.9454154299231552 0.0517249991513963 1.0 0.1169855120994198 5 Q8IXJ6 1 +F-type ATPase 0.660485165771002 1.838860063682316 0.0659357711035149 1.0 0.1395608449596262 8 P00846 1 +AKT family 0.9450359712230216 1.8275145046965624 0.0676224473714373 1.0 0.1411209776606207 2 P31749 1 +Mitochondrial amino acid transporter subfamily 0.8127686260962599 1.7374151644113225 0.0823139164794848 1.0 0.1605010833413768 4 O43772,Q9Y619 2 +SET domain 0.8099625683846893 1.725665612178283 0.0844075879625898 1.0 0.1639788297931394 4 Q9H7B4,O96028,Q8WTS6 3 +Extracellular structure 0.6086527133593683 1.7182710851398972 0.085747180866643 1.0 0.1657119431477803 10 O75718,Q9Y2T2,Q32P28,O00189,P55081,Q92791 6 +Esterase 0.5580483816152948 1.717598938682933 0.0858697940550294 1.0 0.1658017832019984 12 Q8IY17,Q969T7,P50897,Q9UMR5 4 +Receptor 0.4221988471649794 1.5533331561589263 0.1203435630477494 1.0 0.2085189183118521 31 Q9UQB8,Q14108,O75381,Q13432,Q9NR77,Q8WTV0,Q567V2,A6NIH7 8 +Epimerase/racemase 0.5231516035094954 1.5313641182942817 0.1256794269760051 1.0 0.2153656899714705 13 Q8NBZ7,Q9NRG7 2 +Transporter 0.3115306977253234 1.5234557829699522 0.1276447150751298 1.0 0.2174492488730013 204 P06576,Q99523,P00846,Q93050,Q96ES6,Q9BQT8,Q9UBX3,Q12768,P08183,Q15070,Q9BQE5,Q9Y619,O00400,P41440,Q99808,Q9H444,Q9UI14,Q9P253,Q9Y5Y0,Q8NFH4,P37198,Q15363,Q9UJS0,P24390,Q99567,Q99805,Q15043,P30825,Q13596,O43760,P11166,P52292,Q9H2J7,Q5SQN1,P98194,O95721,Q9BSK2,Q8N1F7,Q96NB2,Q8NEW0,O43772,Q70HW3,Q9UNZ2,Q8IXU6,Q9H2V7,P53985,P57740,O75947,Q5T3U5,Q08379,Q9HD45,P33527,Q9P2W9 53 +HDAC class III 0.8831773934259888 1.463353823003924 0.1433705871646775 1.0 0.2369204391841181 3 Q8IXJ6 1 +Methyl-lysine/arginine binding protein 0.622696485280979 1.4567102083865648 0.1451963906765867 1.0 0.238850255961938 7 Q13185,Q16637,Q12888,P45973 4 +Phosphorylase 0.6511963086189132 1.455097486890743 0.1456422748256856 1.0 0.2392223790123251 6 Q9BQG2 1 +Nucleotide phosphatase 0.5493512557868987 1.317703917046311 0.1876027827990118 1.0 0.2878722164885283 9 Q5TFE4,Q9H857,O43681,P49902 4 +Oxygenase 0.6205261204320965 1.3081504300726898 0.1908222913829127 1.0 0.2909354692185668 6 Q16850,Q9Y2Z9 2 +Tubulin 0.6570109046895831 1.287713168972308 0.1978458277201431 1.0 0.2983617373956208 5 P07437,P68371 2 +Bromodomain 0.5877002097648508 1.2814478895409178 0.2000363923489523 1.0 0.3002385115378743 7 Q6PL18,Q9NPI1,O60885,Q86U86 4 +NAK family 0.8083453237410059 1.2581844245013314 0.2083250665286617 1.0 0.3095034071619545 2 O14976 1 +Protein methyltransferase 0.5221329075348304 1.2336340443098248 0.2173393010982134 1.0 0.3185497966298175 10 Q9H7B4,O96028,Q8WTS6,Q96L73 4 +Immune response 0.6396553703927952 1.208806177221229 0.2267373178487455 1.0 0.3276933498835884 5 Q9NX40 1 +Reductase 0.4561107768999756 1.1880459556684164 0.2348153047256291 1.0 0.335582502422848 16 P14927,Q9H7Z7,P00374 3 +Aspartic protease 0.6777589043922538 1.1645360635606272 0.2442068372316868 1.0 0.3444834789446981 4 Q8TCT9,Q5BJF2 2 +F-type and V-type ATPases 0.4423037211200352 1.130996542748083 0.2580565465746907 1.0 0.3559513353006183 17 P56385,P06576,P00846,Q93050,Q9UI12,P56134,O75947,Q9Y5K8 8 +Cytokine 0.7703597122302142 1.1008323271338123 0.2709696393409748 1.0 0.3681671082249801 2 Q13123 1 +Writer 0.4785972100138009 1.0995621128912032 0.2715229571632371 1.0 0.3686889031805053 11 Q9H7B4,O96028,Q8WTS6,Q96L73 4 +PDHK family 0.7689208633093507 1.0949103435532623 0.2735559170653947 1.0 0.3705253652788742 2 Q15118 1 +ATP-binding cassette transporter family 0.5141745998311094 1.0649829369091075 0.2868836513638517 1.0 0.3833328789389381 8 P08183 1 +Guanyl-nucleotide exchange factor 0.6513101065361427 1.052068743933908 0.2927680111317263 1.0 0.38833661890676 4 Q9UJ41,Q9Y4G8,Q14C86 3 +Oxidoreductase 0.2862821659344015 1.0204267449690425 0.307526115058262 1.0 0.4010729811957453 120 Q16134,Q9P0J0,O95831,Q9BY49,Q9Y2Z9,O94788,Q13423,P00374,P14927,Q15067,P30837,Q02252,O43169,P00367,Q8N4Q0,Q15392,Q9H7Z7,Q9BV57,Q16850,P36551,O95169,P14406 22 +ABCC subfamily 0.7419854709330536 0.9205204639416724 0.3573008441498269 1.0 0.4449406738469542 3 P33527 1 +Damaged DNA-binding protein 0.6186079718917888 0.914258807788068 0.3605808697522736 1.0 0.4480006470738459 4 P54725,Q9NYH9 2 +Oxidase 0.3863819986559642 0.902556072792079 0.3667615490609324 1.0 0.4522867343101772 21 O75845,O15254,P36551,Q15067,P14406,O43169 6 +Chromodomain 0.5626393520748801 0.861166130822121 0.3891465510053593 1.0 0.4730245100839665 5 Q14781,Q13185,P45973 3 +Lipid kinase 0.4973638786968013 0.7212604522762099 0.4707492841621929 1.0 0.5384936664418363 6 Q8TBX8,Q9BTU6 2 +Mitochondrial nucleotide transporter subfamily 0.4362362231287942 0.701233271243467 0.4831574493998236 1.0 0.5483740036166496 9 Q70HW3 1 +Microtubule binding motor protein 0.3784517424960386 0.6961673571858399 0.486324027757226 1.0 0.5500790326458749 17 Q86Y91,O95235,Q92845,Q13561 4 +SNARE protein 0.387582786144202 0.6663177384743385 0.5052080298502695 1.0 0.5617742331102648 12 Q9P2W9,O95721,O60499,Q5SQN1 4 +DNA helicase 0.3744234838552602 0.627316464701513 0.5304518128961959 1.0 0.5782402645084658 15 P33991,Q14566,P12956,Q14191 4 +Non-protein kinase 0.3434080476137425 0.5177301312292166 0.6046465723252841 1.0 0.6289017356850376 19 P55263,Q8TBX8,Q9BTU6,P35790 4 +Heterotrimeric G-protein 0.4699995102417078 0.4695084426323201 0.6387062516036233 1.0 0.6605423627695591 5 Q8NHH9,P08754 2 +ROCK subfamily 0.599712230215824 0.4530132545647292 0.6505391972291568 1.0 0.6718228409507366 2 Q13464 1 +DMPK family 0.599712230215824 0.4530132545647292 0.6505391972291568 1.0 0.6718228409507366 2 Q13464 1 +Miscellaneous SLC25 mitochondrial transporters 0.5827338129496368 0.3992854245654466 0.6896829055509515 1.0 0.7108988964931245 2 Q9Y6C9 1 +C2H2 zinc finger transcription factor 0.3974063400576274 0.3679877170339328 0.7128823929639234 1.0 0.7337702513588966 7 Q9Y2X9,Q9UQR1,Q9H582,Q7Z3K3,Q9Y467,O95785 6 +PI3/PI4 kinase family 0.5786801543001485 0.3643365221091328 0.7156067305424996 1.0 0.7362264804542107 3 Q9BTU6 1 +Lyase 0.3261409438531542 0.3532432930816839 0.723906054044583 1.0 0.7444133077002368 16 P22830 1 +Zinc finger transcription factor 0.3281201901290417 0.2714189150049552 0.7860688558006985 1.0 0.8034058976696018 11 O94880 1 +Extracellular matrix glycoprotein 0.4142597188459542 0.2688526462443243 0.7880430784445731 1.0 0.8050458840770545 5 Q9Y2T2,Q32P28 2 +Methyltransferase 0.312768926480418 0.2626630819403656 0.7928102741986209 1.0 0.8095362293504906 13 P31939,Q08J23 2 +Acyltransferase 0.3050215056567897 0.226086019779426 0.8211345177039693 1.0 0.8368886193538816 13 P49354,Q9Y679,P14324,Q92696,P35610,Q7Z6K3,P49356 7 +TAO subfamily 0.5153956834532334 0.2188024446994577 0.8268039424232536 1.0 0.8422726784835577 2 Q9UL54 1 +Translation initiation factor 0.2842858456846592 0.2175501590174115 0.8277796216213971 1.0 0.8428723776958406 22 P55010 1 +Antibacterial response protein 0.5021582733812909 0.1902646832706223 0.8491017267762198 1.0 0.8629694637977633 2 Q9NUQ3 1 +Protein kinase 0.2419734308687116 0.1834737868037186 0.8544262847462392 1.0 0.8675713045115659 79 Q15118,Q13464,P50750,Q2M2I8,P07948,Q15120,P33981,Q96KB5,P49761,P31749,P31751,Q9P289,P51812,O14976,Q15418,Q8IV63,Q9BVS4,Q7KZI7,Q9NYV4,Q13546,Q86UE8,O60566,P05771 23 +Kinase inhibitor 0.3429394812680037 0.1666443957727125 0.8676498593191044 1.0 0.8793584893424893 7 Q5VT52,Q96P16,Q14202,Q9UBW7,Q9NQG5,Q2TAL8 6 +STE20 family 0.3400576368875997 0.1575140050510034 0.8748397712337259 1.0 0.8862330333707232 7 Q9UL54,Q9P289,Q13177,Q9H2G2,Q7L7X3,Q13043 6 +SLC12 family of cation-coupled chloride transporters 0.4811510791366863 0.1500127921677162 0.880754522777675 1.0 0.8918100188794867 2 Q9BXP2 1 +Atypical group 0.3510776777659812 0.1449205650594529 0.8847735892724988 1.0 0.8954632330090625 6 Q15118,Q9BVS4 2 +Endodeoxyribonuclease 0.4566906474820104 0.110950892987858 0.9116552879286864 1.0 0.9205309305093552 2 Q92889 1 +SRC family 0.440287769784168 0.08934105798502 0.92881086495875 1.0 0.9367633881808358 2 P07948 1 +Decarboxylase 0.3364997121473707 0.0025105878390776 0.9979968428289944 1.0 1.0 3 P23368,A1L0T0 2 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0b70708329d893708323401d7fd77e1067304d4c --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome non-ATPase regulatory subunit 9", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-Ketosteroid receptors", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S27", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5'-nucleotidase domain-containing protein 3", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AKT family", "AMP deaminase 2", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-1A", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-4 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent DNA helicase Q4", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 1", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-beta A4 protein", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Ankyrin repeat and SAM domain-containing protein 1A", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Ap2-associated protein kinase 1", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arylsulfatase A", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "B-cell receptor-associated protein 31", "B9 domain-containing protein 1", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-adducin", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "Bromodomain-containing protein 7", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDC7 family", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CLK family", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type ii subunit delta", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-2", "Caspase-3", "Caspase-7", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle 7-related protein kinase", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere-associated protein E", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "Chondroitin sulfate glucuronyltransferase", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA helicase", "DNA helicase MCM8", "DNA ligase", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA repair endonuclease XPF", "DNA replication complex GINS protein PSF1", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC2", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity protein kinase clk3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-3", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase XIAP", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D2", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Esterase", "Ethanolamine kinase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FAK family", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Feline leukemia virus subgroup C receptor-related protein 1", "Ferritin heavy chain", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Focal adhesion kinase 1", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GA-binding protein alpha chain", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Geranylgeranyl transferase type-2 subunit beta", "Glia maturation factor beta", "Glucocorticoid receptor", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Hepatoma-derived growth factor-related protein 3", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Homeodomain transcription factor", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 1", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Katanin p60 ATPase-containing subunit A1", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-associated protein 3", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF18A", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LIM domain-binding protein 1", "LIM domain-containing protein 1", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat flightless-interacting protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligand-dependent corepressor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MAPKAPK family", "MAPKAPK subfamily", "MARK subfamily", "MAX gene-associated protein", "MCU family", "MHC class II regulatory factor RFX1", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MSN subfamily", "MST subfamily", "MTSS1-like protein", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Map kinase-activated protein kinase 3", "Map/microtubule affinity-regulating kinase 3", "Mediator of RNA polymerase II transcription subunit 14", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Metal-response element-binding transcription factor 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase kinase 4", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multidrug resistance-associated protein 7", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 4", "Myotubularin-related protein 6", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "N6-adenosine-methyltransferase non-catalytic subunit", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NAD-dependent protein deacetylase sirtuin-3, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADH-ubiquinone oxidoreductase chain 4", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neural Wiskott-Aldrich syndrome protein", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PKA family", "PKC alpha subfamily", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Patatin-like phospholipase domain-containing protein 2", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-B-cell leukemia transcription factor 2", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 39", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SLU7", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX34", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein DDI1 homolog 2", "Protein ENL", "Protein ERGIC-53", "Protein FRG1", "Protein Hook homolog 1", "Protein Hook homolog 2", "Protein Mpv17", "Protein NDRG1", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A11", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein VAC14 homolog", "Protein Wiz", "Protein XRP2", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c beta type", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein prenyltransferase alpha subunit repeat-containing protein 1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RIO family", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab proteins geranylgeranyltransferase component A 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rab5 GDP/GTP exchange factor", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related C3 botulinum toxin substrate 3", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinoblastoma-associated protein", "Retinoblastoma-like protein 1", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho GTPase-activating protein 18", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 1", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC49 family of FLVCR-related heme transporters", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sal-like protein 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Sedoheptulokinase", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine-protein kinase atm", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 12", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase tao1", "Serine/threonine-protein kinase tao2", "Serine/threonine-protein kinase tousled-like 2", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-dependent multivitamin transporter", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Speckle targeted PIP5K1A-regulated poly(A) polymerase", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Synaptosomal-associated protein 47", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAO subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 8B", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TLK family", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor p65", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 6", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transcriptional repressor protein YY1", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin polyglutamylase TTLL4", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "Tyrosine-protein kinase yes", "Tyrosine-protein phosphatase non-receptor type 9", "Tyrosyl-DNA phosphodiesterase 1", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 22", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 34", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 38", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 J2", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-Ie", "Unconventional myosin-VI", "Unconventional myosin-Va", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit G 1", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VIP36-like protein", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 11 homolog", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 52 homolog", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 34", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WNK family", "Werner syndrome ATP-dependent helicase", "Winged helix/forkhead transcription factor", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger HIT domain-containing protein 2", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 3", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger and BTB domain-containing protein 10", "Zinc finger protein 148", "Zinc finger protein 281", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 7", "Zinc transporter ZIP14", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "AMPD2", "ANAPC1", "ANGEL1", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APEH", "APOL2", "APP", "ARCN1", "ARFIP1", "ARHGAP18", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATG3", "ATG4B", "ATIC", "ATL2", "ATM", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B9D1", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDC7", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CENPE", "CEP170", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHERP", "CHKA", "CHM", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COASY", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ6", "CORO1B", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FLVCR1", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FRG1", "FSCN1", "FTH1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GINS2", "GLB1", "GLDC", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HEATR1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK1", "HOOK2", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LCOR", "LDB1", "LDHA", "LDHB", "LETM1", "LGALS3", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRRFIP1", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LTN1", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARK3", "MARS2", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED14", "METTL1", "METTL14", "MFAP1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MLLT1", "MMS19", "MOB4", "MORF4L1", "MPC2", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL38", "MRPL39", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTSS1L", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "ND4", "NDC80", "NDRG1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NEDD4", "NEDD4L", "NEK9", "NF1", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKACA", "PRKAG1", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSPC1", "PTAR1", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN9", "PTPRF", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RAC3", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RB1", "RBBP6", "RBL1", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "RECQL4", "REEP4", "REEP5", "RELA", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNH1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A11", "SAE1", "SALL2", "SAP18", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCPEP1", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SHPK", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLK", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAOK1", "TAOK2", "TAP1", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLK2", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM259", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRMT6", "TROVE2", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTLL4", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TUT1", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2J2", "UBE2L3", "UBE4A", "UBE4B", "UBIAD1", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP28", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS11", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS52", "VRK1", "VRK3", "WARS", "WASHC5", "WASL", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR74", "WDR82", "WIZ", "WNK1", "WRN", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YEATS4", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF148", "ZNF281", "ZNF598", "ZNF644", "ZNHIT2", "ZW10", "ZYX"], "leading_proteins": ["AAK1", "ABCB1", "ABCC1", "ABCC10", "ACOX1", "ACOX3", "ADI1", "ADK", "AIFM1", "AKT1", "AKT2", "ALDH1A2", "ALDH1B1", "ALDH6A1", "AP3M1", "AP4M1", "APOL2", "ASNA1", "ATAD2", "ATG4B", "ATIC", "ATL2", "ATP2C1", "ATP5B", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V1D", "ATP6V1H", "AUP1", "BAIAP2", "BRD4", "BRD7", "BUB1B", "CALM3", "CALU", "CARM1", "CBX2", "CBX3", "CBX5", "CCAR2", "CDC40", "CDK12", "CDK9", "CETN2", "CHKA", "CHMP4B", "CIRBP", "CLK3", "COPS5", "COPS8", "COQ6", "COX7A2", "CPOX", "CPVL", "CRTAP", "CSTF2", "CYB5B", "CYB5D2", "CYP51A1", "DCTN2", "DHCR24", "DHFR", "ECE1", "EIF5", "EPHX2", "ERAP1", "ERCC4", "ERMP1", "ETFDH", "EWSR1", "FDPS", "FECH", "FLVCR1", "FNTA", "FNTB", "FUBP1", "FUBP3", "FUS", "GAK", "GAPVD1", "GLUD1", "GNAI3", "GOLGA2", "HDGF", "HDGFL2", "HDGFL3", "HM13", "HNRNPK", "IK", "ILVBL", "KDELR1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF18B", "KIF20A", "KIFAP3", "KPNA2", "LNPEP", "LSM3", "LSM6", "LYN", "MARK2", "MCM4", "MCM6", "ME2", "MECP2", "MFAP1", "MFSD3", "MIA2", "MICU2", "MPV17L2", "MTCH2", "NAP1L1", "NCL", "NDUFA13", "NDUFB8", "NLN", "NLRX1", "NNT", "NONO", "NPEPPS", "NRDC", "NSD1", "NSD2", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NUCB1", "NUCB2", "NUDT12", "NUP107", "NUP37", "NUP62", "NUP88", "NUP93", "OCIAD1", "OTUD4", "OXA1L", "P3H1", "P3H4", "PAK2", "PARN", "PBK", "PBRM1", "PDK1", "PDK3", "PECR", "PEX14", "PGRMC1", "PGRMC2", "PHF14", "PHIP", "PI4K2A", "PIP4K2C", "PITRM1", "PLBD2", "PMPCA", "PNPLA6", "POGZ", "PPT1", "PPT2", "PRCP", "PRKCB", "PRPF39", "PSIP1", "PSPC1", "PTAR1", "PTGES2", "PTPA", "PXMP2", "QKI", "QRICH1", "RABAC1", "RABGEF1", "RABGGTA", "RAD23A", "RAPGEF2", "RAVER1", "RBM14", "RBM17", "RBM3", "RBMX", "RBMXL1", "RCN2", "RIOK2", "RIPK1", "ROCK1", "RPRD1A", "RPRD1B", "RPRD2", "RPS6KA1", "RPS6KA3", "SALL2", "SC5D", "SCARB1", "SCARB2", "SCPEP1", "SDF4", "SDR39U1", "SEC11A", "SET", "SETD7", "SF1", "SF3A1", "SFPQ", "SFXN2", "SIRT1", "SIRT2", "SIRT3", "SLC12A9", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A33", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35F2", "SLC39A14", "SLC6A15", "SLC7A1", "SLK", "SLU7", "SMN1*", "SMYD3", "SNAP29", "SNAP47", "SNX1", "SOAT1", "SORT1", "SPNS1", "SRSF1", "SRSF10", "SRSF12", "SRSF2", "SRSF9", "SSR1", "STAMBP", "STK26", "STK4", "STX10", "STX18", "SUGP1", "SYNGR2", "TAF15", "TAOK1", "TAOK2", "TFIP11", "TLK2", "TM9SF2", "TM9SF3", "TMED2", "TMEM97", "TMPO", "TP53BP1", "TRA2A", "TRA2B", "TTK", "TUBB", "TUBB4B", "TXLNG", "UNC119", "UNC119B", "UQCRB", "UQCRC2", "USP28", "UTP6", "UXS1", "VPS18", "VRK3", "WASHC5", "WIZ", "WRN", "XRCC6", "ZADH2", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZNF148", "ZNF281", "ZNF644"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8a1fdd7a413878380ac3bc59fc785bad9e9e1fdd --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark", "1": "Tclin", "2": "Tchem"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..81daec4255321e138c1de4b509478a014acad30c --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a5f31a16bfec4281f528e18c5763b7f568d9038a2282baf0c13c38a5bf871cc +size 134331 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..97eec11999a974aca2278bb823439bfccd5d0a03 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7591422e93db3b490f7a53a936f68ef54d356af2cbc7a916abdbcaebb2e369c2 +size 132685 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..9a408c52a43f294bcb0c131f8efd783e744e0949 --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab6d1b4c484c7cb0f33141785d1934865479ac805c6bff17bb9bbf2f5f6a0db4 +size 133731 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3246ea7e0dce28340c699e6d7586a8ce436ea294 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5c201f104ed157eae94ce848529828f525ada761b7c50b9cf9918dadf7430eb4 +size 86135 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..faf3e605d8f42e2bfb2d1161a902cd632c15cf96 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 869.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3fc235d4a381a49f60e68fd9654ed752c4fb49fe --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f71f56be33877cf9af53f2e988ae1d67040dd45e --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tdark 0.3142432420479518 1.272495118562299 0.2031972573775398 0.5969088333667283 0.3580044530830522 376 Q5T3I0,Q5R3I4,O60830,O95302,Q9Y605,Q9H501,Q96SK2,Q9C0F1,Q96F63,Q8WUJ1,Q9NRG7,Q9P2K5,Q9Y6I9,Q69YU5,Q9Y3C1,Q5QJE6,Q9H7E9,Q9BQ61,Q8ND82,Q5TFE4,Q9H4I3,Q9BVL2,Q99805,Q96ER3,Q7Z4Q2,Q5W0B1,O75935,Q70UQ0,Q8IZ73,O43615,Q96NB2,Q16540,Q8N684,P14406,P62312,Q9H1Z9,Q15629,Q9NRG0,Q9HD45,Q9NRY5,Q6UW68,Q7Z2K6,Q969T7,Q68DH5,Q9NUQ9,Q5VWN6,Q5JSZ5,Q1KMD3,P49750,Q9BVJ6,Q92575,Q96E39,A0AVF1,Q86X53,Q969E8,Q9HD20,Q9NVZ3,Q96PV6,Q8N4V1,Q86UA1,Q15006,Q9BVI4,Q9H1I8,Q8IXU6,Q9Y2G8,Q8NC44,P82663,Q96DE5,Q9Y4W2,Q9NVM9,P82933,O75964,Q92564,Q9NX00,Q9NR77,Q9NX08,Q8N8A6,Q6P3X3,Q14320,Q9H1E5,Q9NW68,Q9Y3B9,Q6UW02,Q86SX3,Q86X83,Q96C92,Q96A49,Q9BSH5,Q15345,Q96LJ7,Q9P013,Q8WUX2,Q8N4H5,Q66K64,Q5TC12,Q8IWB1,Q9BVG4,Q96GA3,Q96ES6,O00193,Q6PK04,Q8IXT5,Q52LJ0,Q8NFH4,Q8WVI0,Q1ED39,Q9H857,Q5SQN1,Q86VM9,Q9BPY3 110 +Tclin 0.3064420680285459 1.1065157753311632 0.2685033398122891 0.7136815130311753 0.3580044530830522 94 P09874,P07437,P00374,O43676,P0DP25,Q99808,O95169,Q99720,Q8N183,Q16739,P48735,P04150,Q9P0J0,O96000,Q9UGN5,P49721,P00813 17 +Tchem 0.2736309243229219 0.3444986189498092 0.7304713344654576 0.9947226020470592 0.7304713344654576 356 P37268,Q15118,Q13126,P30519,Q8IXJ6,Q9BTY2,Q9H7B4,Q99523,O15228,P42892,Q5JRX3,O60725,Q15257,Q8WTV0,P07099,P55263,Q9H773,P34913,P55786,P08183,Q4J6C6,O00400,P41440,P30536,P31939,Q9NTG7,O60502,P49761,P31749,P46934,P31751,P51812,Q15418,Q9H7Z7,P23786,P45880,Q9UIQ6,Q6Y7W6,P09601,P13674,Q13432,P35790,P42785,Q16850,Q9UPP1,Q02818,P48449,Q9NPI1,P53985,P09960,P14174,P33527,P05067,O95749,Q9NZ08,P05771 56 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8db104d81551084be0e1d659d135c74abf69a249 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APC", "APEH", "APEX1", "APEX2", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC8", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD5", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRI3BP", "BRIX1", "BRMS1L", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C11orf98", "C12orf29", "C12orf57", "C12orf73", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf123", "C1orf198", "C1orf35", "C21orf59", "C2CD2", "C2CD5", "C2orf49", "C3orf38", "C3orf58", "C5orf15", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CENPB", "CENPE", "CENPF", "CENPI", "CENPK", "CENPM", "CENPU", "CENPV", "CEP131", "CEP170", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COIL", "COLGALT1", "COMMD2", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX18", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSN1", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC8", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERICH1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM114A2", "FAM118B", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM136A", "FAM162A", "FAM192A", "FAM208A", "FAM208B", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXL18", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLVCR1", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSD1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAUS7", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGN5", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JCAD", "JPT2", "JUP", "KARS", "KAT2A", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNL1", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "LAMP1", "LAMTOR1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT1", "LCOR", "LDAH", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRFIP1", "LRSAM1", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP4K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED17", "MED23", "MED24", "MED4", "MEN1", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA20", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND4", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKBIE", "NFS1", "NGDN", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OFD1", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD2L", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTAR1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABAC1", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG2", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RFX1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "ST7", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD7", "STARD9", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", 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2.6806593569174044 0.0073477270122881 26.983009708737864 120.21844660194176 0.6636399997719048 0.5877814963058052 7.904294191754799 11.993762517847651 0.9312427807662368 0.388650277956022 0.0937335938798229 0.5169656199025946 0.4676374907577512 0.0603104635775787 0.0200123517654044 +mRNA transport 28 67 2.4142292334239883 0.0157685381753183 19.95873786407767 63.91504854368932 -0.358516574552051 0.6748674948018153 8.780535974486178 3.622350621733038 0.8870590316614543 0.3188736462317489 0.5251316823550114 1.0 1.0 0.1788573615140471 0.0014814450147948 +ATP synthesis 2 8 2.2300591422538023 0.0257435168095532 2.6092233009708736 7.560679611650485 0.4760838469956283 0.2927439020529209 1.766795238887657 0.7130595396318904 1.333549443047025 0.2645430394314645 0.2078873733672205 0.0550816697898294 0.1094892401774078 0.2550529546148332 0.0182159139614431 +mRNA splicing 75 191 2.172300747319971 0.029832985706288 59.87864077669903 175.22087378640776 -0.7075775257571115 0.5175064000956785 19.698204296875492 10.3178726646473 1.3294981077758468 0.3577038931902551 0.0046740861058957 0.7142037034973352 0.2444285312599412 5.50278128259604e-06 2.2903285562254908e-11 +Meiosis 3 17 2.164573490464293 0.0304203629617725 3.616504854368932 15.606796116504857 0.2120263035153013 0.6171698443628355 2.6773990090869777 1.3884937802701875 0.7381070435408833 0.2876519570703926 0.1653357597547718 0.1644315705571846 0.3076603852203092 0.063688713570506 0.1120371510488811 +Neurogenesis 9 51 2.10184752244891 0.0355666347235246 10.516990291262136 45.939320388349515 0.2242732208357797 0.6531887775233043 4.53328602713189 5.519049756773321 0.7470549871157102 0.3099879557492902 0.1095640509147512 0.1905183490980548 0.2241571179829831 0.2306216121886583 0.3163302096033431 +Autophagy 10 34 2.033838331690612 0.0419678983331583 8.390776699029127 32.08009708737864 0.0236963635391968 0.6475755054878071 3.8936358802040543 5.484390204289273 0.7913712909049914 0.3067150875835953 0.6885077138323863 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file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..35ab3d820be28c7f0f40e9179cba8ebf29e4a6bd --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,61 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Translocation 0.5515215141337017 3.3415070825680337 0.0008332489061551 0.1335739832415377 0.0592095732502337 46 Q99595,O60830,Q8TD16,P35658,Q9NS69,O60318,O14925,P49790,Q8NFH4,P37198,Q99567,Q9BVL2,O75381,Q3ZCQ8,O15504,Q9BTX1,O43615,Q8N1F7,P57740,P41208,Q15629,P52948 22 +Apoptosis 0.3536591567546024 2.6806593569174044 0.0073477270122881 0.7187397771163095 0.0702116136729755 138 P21796,O75940,Q9UHX1,P46379,Q8N163,Q03164,P04150,Q9P0J0,Q13501,O95831,Q96EB6,Q9BXK5,Q9HB09,Q53EL6,Q07021,P61289,Q9ULW0,P31749,Q14728,P31751,Q9NR28,Q9Y3D6,P09601,Q01085,Q9UER7,Q96IZ0,O14681,P52756,Q13546,Q9UDX5,O14737,P42575,Q9H2J4,P05067,P05771 35 +mRNA transport 0.4052206087810953 2.4142292334239883 0.0157685381753183 0.9350280522571052 0.1130078569231145 67 Q07955,Q8TD16,P82979,P35658,O60318,Q96FV9,P22626,P49790,Q16629,P49792,Q96PU8,P09651,Q96ST2,Q8NFH4,Q53F19,P37198,Q06787,Q99567,Q9BVL2,Q6I9Y2,O15504,Q9BZI7,Q9BTX1,Q8N1F7,Q92945,P57740,P41208,P52948 28 +ATP synthesis 0.7378644314771433 2.2300591422538023 0.0257435168095532 0.9887329979895436 0.1372730950972713 8 O75964,P00846 2 +mRNA splicing 0.3415074908137369 2.172300747319971 0.029832985706288 0.9945348916475244 0.149494355126425 191 O60506,Q07955,O75940,Q9UHX1,Q9Y2W1,Q14562,Q8N163,Q9ULX6,P07910,O43390,Q13123,Q9UBB9,Q96FV9,Q13148,P98175,O60828,P22626,Q13595,Q14320,Q96MU7,Q6NZY4,Q9Y2W2,Q13573,O75400,Q5T200,Q92841,Q15459,O95391,P09651,P62310,P62995,Q96PU8,O75934,P38159,Q96ST2,Q07021,Q9Y3B4,Q8IWZ8,Q96I25,Q99590,Q15020,Q16637,Q06787,P23246,P67809,Q6I9Y2,O60508,Q96E39,P52272,P55081,O75494,Q12874,Q9P013,Q01130,Q15233,P52597,Q92945,Q86UA1,Q15637,O75312,P52756,Q8WXF0,Q13242,Q9BWF3,Q96DF8,Q8WWY3,Q92917,P62312,P51991,O95400,Q15427,P31943,O43290,P61978,Q15007 75 +Meiosis 0.5960090197366719 2.164573490464293 0.0304203629617725 0.9950755290440472 0.149494355126425 17 P16104,Q9UQ84,Q8IXJ6 3 +Neurogenesis 0.4187344743331988 2.10184752244891 0.0355666347235246 0.9980283810103746 0.1699294770123953 51 P16949,P55209,Q16637,Q8IXJ6,Q969G3,Q16352,Q8WUJ1,P31749,P46934 9 +Autophagy 0.457543809199942 2.033838331690612 0.0419678983331583 0.9993728511934392 0.1907082757982445 34 Q9NRR5,Q8IXJ6,Q9Y4P1,Q9Y6I9,Q5T8D3,Q13501,Q9P253,O95721,Q7Z3C6,Q6UWE0 10 +Detoxification 0.9922302158273382 2.021365021916085 0.0432419927682066 0.9995011589789208 0.1907082757982445 2 P07099 1 +Aromatic hydrocarbons catabolism 0.9922302158273382 2.021365021916085 0.0432419927682066 0.9995011589789208 0.1907082757982445 2 P07099 1 +Ubiquinone biosynthesis 0.7946889634100252 1.904293960846586 0.0568719103142099 0.9999577178621666 0.2329040136677167 5 Q5T2R2,Q9Y5Z9,Q9Y2Z9 3 +mRNA processing 0.3324453976527688 1.862624266611048 0.0625151477504997 0.9999849390426024 0.2500605910019988 223 O75940,O75400,Q92841,P38159,P31942,Q96I25,P23246,P52272,P55081,Q15233,P52597,O75312,Q8N684,P62312,Q15427,P31943,Q8N163,Q9ULX6,P33240,O60828,P22626,Q9Y2W2,Q5T200,Q15459,O95391,P62310,P62995,Q96ST2,Q16637,Q6UN15,Q6I9Y2,Q96E39,O75525,Q01130,Q92945,Q86UA1,Q15637,P52756,Q13242,Q9BWF3,Q96DF8,P51991,O95400,Q07666,P61978,O60506,Q07955,Q9UHX1,O43390,Q13123,Q9UBB9,P98175,Q13595,Q14320,P09651,Q96PU8,O75934,Q07021,Q9Y3B4,Q53F19,Q99590,Q15020,Q06787,Q9H0D6,O60508,O75494,Q12874,Q9P013,Q86U42,Q8WXF0,Q12849,Q8WWY3,Q92917,O43290,Q15007,Q9Y2W1,Q14562,P07910,Q96FV9,Q13148,Q96MU7,Q6NZY4,Q13573,Q8IWZ8,P67809 85 +Innate immunity 0.3720069422796664 1.8063315163323068 0.0708665717657803 0.9999967683026714 0.2541134963791606 62 Q14166,P23246,Q8IXJ6,Q9Y5A9,Q8WXF1,Q01804,P10321,P12956,P04439,Q07021,Q86UT6,Q9Y3Z3,O43823,P14174,P43243,Q96PK6 16 +Amino-acid transport 0.6916400857559221 1.796639946538887 0.0723927983870864 0.9999975642808524 0.2541134963791606 7 P30825,Q9H2J7,Q96NB2 3 +Zinc transport 0.9056115107913664 1.664026577769461 0.0961071182138137 0.9999999716783726 0.2975756122965126 2 Q8NEW0 1 +Immunity 0.3424832068155491 1.6155841465544505 0.106184253804354 0.9999999958822856 0.3008633535568272 85 P46379,Q8IXJ6,Q9Y5A9,O60318,P04439,P12956,Q86UT6,Q13501,Q92841,Q07021,Q9Y3Z3,Q96PK6,P23246,Q9UQ84,Q01804,P10321,O43823,P43243,Q15233,Q14166,Q66K64,P14174,Q8WXF1,Q9NZ08,P05771 25 +Hypusine biosynthesis 0.8779856115107907 1.5488811835684293 0.1214102850095104 0.9999999997856064 0.3324652078251197 2 P49366 1 +Hydrogen ion transport 0.4580187750168718 1.449296245002005 0.1472548692842692 0.9999999999987385 0.3853523502546924 21 P56385,O75964,Q15904,P06576,P00846,Q93050,O75947,Q9Y5K8,P36543 9 +Peroxisome biogenesis 0.7424036677531308 1.440208478273317 0.1498084252631621 0.9999999999992468 0.3853523502546924 4 P56589,P40855 2 +Notch signaling pathway 0.5827554697315426 1.4314096488963886 0.1523128446486554 0.9999999999995466 0.3853523502546924 8 P05067 1 +Lipid transport 0.4376107891039185 1.431284816860385 0.1523486035890644 0.9999999999995498 0.3853523502546924 23 Q99720,Q9H4L5,Q9BQE5,Q9BZF3 4 +Cilium biogenesis/degradation 0.4183737254267184 1.3740172200319394 0.1694363365093762 0.9999999999999865 0.3905061052099345 27 O95684,Q96C92,O95721,Q15051,A6NIH7 5 +Phospholipid metabolism 0.4652185849220392 1.3337331582105496 0.1822913237912642 0.9999999999999992 0.4088424240826194 18 Q6UWP7,Q9HBU6,P35790 3 +Sugar transport 0.7158185139756392 1.326919048210773 0.1845354625663187 0.9999999999999994 0.4088424240826194 4 P31749 1 +Stress response 0.3957832918236328 1.238929117781882 0.2153717492652838 1.0 0.4681045595678557 29 P98179,Q14011,P51812 3 +Steroid biosynthesis 0.4130615351390726 1.2326053204431997 0.2177230509617933 1.0 0.4681045595678557 23 P37268,Q15392,Q16850,P48449 4 +Exocytosis 0.444684442662969 1.188817255938008 0.2345115861394835 1.0 0.4734972871367313 18 Q12765 1 +Purine salvage 0.634012834584254 1.183152678303653 0.2367486435683656 1.0 0.4734972871367313 5 P55263 1 +Glycogen biosynthesis 0.6250156740729244 1.1422651133864732 0.2533438377564867 1.0 0.4951720465240422 5 P31749 1 +Sterol biosynthesis 0.426671483633749 1.061569742716579 0.2884310558302698 1.0 0.5451663912396308 18 Q16850,P37268,Q15392 3 +Porphyrin biosynthesis 0.6022288378567537 1.038933971945653 0.2988354454629909 1.0 0.5468052831876004 5 P22830 1 +Cholesterol biosynthesis 0.4308146770067853 1.0177663232766794 0.3087890198109653 1.0 0.5532469938279795 16 P37268,Q15392 2 +Osteogenesis 0.7231654676258971 0.9089043590857432 0.3634006126290261 1.0 0.6177852609646655 2 Q99523 1 +Sterol metabolism 0.363184272629001 0.8983850338237936 0.3689803125624062 1.0 0.6177852609646655 27 P37268,O75845,Q16850,P35610,Q15392,Q9UHB6 6 +Transport 0.2721718558369823 0.8926305878883616 0.3720550331048595 1.0 0.6177852609646655 532 Q99595,O60830,P46379,Q9BZF3,P00846,Q93050,Q9NS69,Q9BQT8,A6NIH7,Q12768,P08183,Q99808,O15118,Q9P253,O43169,Q14728,Q6UWE0,P24390,Q9BVL2,P30825,Q3ZCQ8,P23786,P45880,Q13596,O95235,O15504,Q9H2J7,O43823,O43615,Q96NB2,O43772,O95169,Q99720,P57740,Q6DKK2,Q15629,Q5T3U5,P33527,P82979,P21796,O43676,Q9UPN4,P35658,O60318,Q9UBX3,Q9H814,P22626,O14925,Q9Y5X2,Q9BQE5,Q9Y619,P14927,O43681,Q9H4L5,Q96ST2,Q9Y5Y0,Q9HD42,P31749,P37198,P31751,Q6NUQ1,Q96ED9,Q6I9Y2,O75381,Q9UJ41,O75431,A0AVF1,P11166,P52292,Q9HD20,Q9NVZ3,Q9BZI7,O95721,Q13432,Q8N4V1,Q92945,Q15904,Q70HW3,Q9Y2T2,Q8IXU6,P53985,Q6P4A7,O75947,Q9Y5K8,Q8NEW0,Q9Y282,P52948,P51790,O75964,Q07955,P06576,Q99816,Q8TD16,Q16134,O60499,O00189,Q9NV70,Q13505,Q9H1E5,O00400,P41440,P49790,Q9H444,P49792,Q96PU8,P09651,P22695,O75746,Q96C92,O15027,Q9Y5X1,Q53F19,Q92973,Q9UJS0,Q9C0H2,Q06787,Q9UNK0,Q9Y4P1,Q15043,Q9H2D1,Q9BZF1,Q92734,Q8N6H7,Q8N4H5,Q9BSK2,Q8N1F7,Q9H2V7,Q5T8D3,P41208,Q9P2W9,P49321,Q99523,Q96ES6,Q9P0J0,Q9H9H4,Q6WKZ4,Q8N6T3,Q8NFH4,Q15363,Q99567,Q9Y277,P98194,O96000,Q9BTX1,O75489,Q9H6Z4,Q08379,Q7Z3C6 148 +Phospholipid biosynthesis 0.4071975457235023 0.8898534603073629 0.3735445763972396 1.0 0.6177852609646655 17 P35790,Q9HBU6 2 +Heme biosynthesis 0.5227664545141019 0.8399027771419975 0.4009629003998074 1.0 0.6568154177977799 6 P22830 1 +Vision 0.4926265702479824 0.8060201679756449 0.4202312203731315 1.0 0.6631171550842075 7 Q13432 1 +Sensory transduction 0.4926265702479824 0.8060201679756449 0.4202312203731315 1.0 0.6631171550842075 7 Q13432 1 +Steroid metabolism 0.3447073638298635 0.7615970570663604 0.4463005318201727 1.0 0.6837897589632208 28 P37268,O75845,Q16850,P35610,Q15392,Q9UHB6 6 +Symport 0.503325273196628 0.7488711822184501 0.4539348510553764 1.0 0.6848841612414452 6 P53985 1 +Ion transport 0.2927611069214322 0.7205451980827267 0.4711893816168815 1.0 0.7047354229400316 59 P21796,P24539,O75964,P06576,P35670,Q93050,P16615,P00846,P56385,Q9P246,Q9H0H5,Q96S66,P36543,Q4KMQ2,Q9C0H2,Q15043,P45880,Q9Y277,Q9H2J7,P98194,Q9BPX6,Q15904,O96008,Q9UI12,P56134,O75947,Q9Y5K8,Q8NEW0,P51790 29 +Cholesterol metabolism 0.3445444440099626 0.7061407144823215 0.4801006343830436 1.0 0.7118733544300302 25 P37268,Q16850,P35610,Q15392,Q9UHB6 5 +Sphingolipid metabolism 0.3762975196268596 0.5113810457201804 0.60908426455767 1.0 0.851727589462758 11 Q06136 1 +Adaptive immunity 0.3496344582074663 0.490862659828419 0.6235235884720283 1.0 0.857968457737511 16 Q9NZ08,Q07021,P10321,P05771 4 +Glycogen metabolism 0.3993533968294764 0.4750322536053935 0.634763984225541 1.0 0.8665032165618497 8 P31749 1 +DNA recombination 0.3059077389264492 0.4251586843889868 0.6707210003022008 1.0 0.8874154773229118 27 P23246,P16104,Q96B01,Q96SB8,P38398,P12956,Q15233 7 +Isoprene biosynthesis 0.4221134260869852 0.2947558202773704 0.7681804180250751 1.0 0.9773618882157596 5 O95749,Q5T2R2 2 +Electron transport 0.259023194716167 0.261925809369951 0.793378641063849 1.0 0.9863033358815478 49 Q9H1E5,O43676,O95169,P14927,Q16134,Q9P0J0,P22695,Q6DKK2,O43169,O96000 10 +Myogenesis 0.3860677383619215 0.2571399751017569 0.7970707191135764 1.0 0.9863033358815478 6 P51114,Q96EB6 2 +Respiratory chain 0.2638497108785769 0.2069399116557523 0.8360567861110038 1.0 0.9916384730213288 35 O43676,O95169,P14927,Q9P0J0,P22695,Q6DKK2,O96000 7 +DNA synthesis 0.5079236148118922 0.1885196136352755 0.8504693417020013 1.0 0.9916384730213288 3 P04183 1 +Coenzyme A biosynthesis 0.4955395683453194 0.1769122301677373 0.8595773318669084 1.0 0.9916384730213288 2 Q13057 1 +Glucose metabolism 0.2928347870528403 0.1721766431964052 0.8632986596835726 1.0 0.9916384730213288 12 P31751,P31749 2 +Chemotaxis 0.4080046069680441 0.1702659427168978 0.8648009939139496 1.0 0.9916384730213288 4 Q8NHP6,O94813,P09429 3 +Wnt signaling pathway 0.2541895692240337 0.0804622391335447 0.9358696276311782 1.0 1.0 29 Q8N163,Q9NPI1,P25054,Q8N7H5 4 +Transcription regulation 0.2602658988549974 0.0739548939344096 0.9410462763511228 1.0 1.0 344 P18615,Q8IXJ6,Q9H501,P29083,Q9UK61,Q96EB6,Q8WTS6,Q92841,Q5QJE6,Q96PK6,Q8ND82,Q9NPJ6,P23246,O43823,Q9UER7,Q15233,O15047,P09874,Q9UPP1,P82979,P05771,P53999,Q8IXH7,Q8N163,Q9ULX6,Q03164,P50750,P38398,P12956,Q9NYB0,P51858,Q96L73,O14979,Q00577,O60828,Q00403,Q5PSV4,Q96DT7,P49750,Q96ST2,Q9HD42,Q00059,Q5T5X7,Q96AE4,O75525,Q92830,Q96IZ0,Q92945,Q8NEY8,O96028,O60869,Q9NX63,Q96I24,Q07666,P61978,Q9UHX1,Q96JN0,P82970,Q07021,Q86X83,Q9NPI1,Q8WXF1,Q9NYF8,Q9Y2W1,P04150,Q14241,Q13148,P61457,P67809,Q04721,Q01844,O95983,Q8N7H5,O95619,Q6PL18,Q71F23,Q9HCD5 77 +Cell cycle 0.246805093096037 0.0458131681270849 0.9634591631839622 1.0 1.0 250 O43663,Q9Y266,Q9UPN4,Q8IXJ6,P16104,Q9Y5A9,Q8N163,Q7Z5K2,P38398,P04150,Q86XL3,Q9H6D7,Q9UJX3,Q29RF7,Q9BRP1,Q69YH5,P33991,Q9NTI5,O75400,Q08J23,Q9UKG1,Q9BXW9,Q8WW12,Q92733,P61289,Q96C92,Q8NFH4,Q9HD42,Q9ULW0,Q13111,Q2NKX8,Q6NUQ1,Q9NQS7,P51812,O14976,Q8NG31,Q15418,Q96EA4,Q9BVS4,O75935,Q96DY7,Q69YQ0,Q86Y91,Q86WB0,Q9UPP1,Q8TAE8,Q96CS2,Q9NPI1,Q14566,Q96DE5,Q6DKK2,Q9UJX2,Q9NVM9,Q9HAW4,Q07666,Q86Y37,P41208,Q08379,P49321,Q15007 60 +Differentiation 0.2323874847215004 0.0371535455342884 0.970362578309313 1.0 1.0 99 Q9UPN4,P46379,Q8IXJ6,Q99523,Q9Y5A9,Q13501,Q96EB6,P16949,Q08J23,Q96PU8,Q96A49,Q04721,O96005,Q16352,Q7KZI7,P51114,O75312,O60869,Q96EP5,Q96PU5 20 +Cell adhesion 0.2389853845729019 0.0034547955203151 0.9972434774770746 1.0 1.0 31 P00813,P05067 2 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..858b925ad2cd55ce331bf3fa3d1b4942632e44be --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Iron storage", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMFR", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APC", "APEX1", "APEX2", "API5", "APOL2", "APOO", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6IP1", "ARL8A", "ARL8B", "ARMC9", "ARMT1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "AUP1", "AURKA", "B9D1", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BEND3", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C2CD5", "C3orf38", "CACUL1", "CACYBP", "CAD", "CADM1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CASP2", "CASP3", "CASP7", "CBL", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCDC94", "CCNA2", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CENPE", "CENPF", "CENPU", "CENPV", "CEP131", "CERS1", "CERS2", "CERS5", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAO1", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "COASY", "COG5", "COG7", "COMMD2", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPZ1", "COQ6", "COQ8A", "COX2", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREBBP", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF15", "DCAF7", "DCP1A", "DCPS", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DEGS1", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC2", "DSC3", "DSG2", "DSN1", "DST", "DTL", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHHADH", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC4", "EMG1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXL18", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FLVCR1", "FMR1", "FNBP1L", "FOXRED1", "FRG1", "FRYL", "FSD1", "FTH1", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA2", "GGPS1", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSS", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAUS7", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGN5", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HOOK2", "HOXD13", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IRF2BP2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JCAD", "JUP", "KARS", "KAT2A", "KAT7", "KATNA1", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "LAMP1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCOR", "LDAH", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC41", "LRRC8A", "LRRFIP1", "LRSAM1", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MANF", "MAP1S", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED14", "MED16", "MED17", "MED23", "MED24", "MED4", "MEN1", "MESD", "METTL1", "METTL14", "METTL3", "MFAP1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MLLT1", "MMGT1", "MMS19", "MMS22L", "MOB4", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPHOSPH10", "MPHOSPH8", "MRE11", "MRI1", "MRPL41", "MRPL58", "MRPS27", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND4", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NGDN", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUCKS1", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OFD1", "OGDH", "OGT", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PANK4", "PAPOLA", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD2L", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMAIP1", "PMVK", "PNN", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "PPAT", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAG1", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK2", "PTK7", "PTPMT1", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABGAP1", "RABGEF1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "REEP4", "RELA", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHOA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN3", "RMND1", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP14", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", 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setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proto-oncogene 18 47 2.1406324171739555 0.0323036924546928 10.220873786407768 42.230582524271846 0.352417122717188 0.6349839081636985 4.025676233803451 6.092151297173746 0.7870476016467428 0.3240376141995099 0.0248285517249215 1.0 0.0551812689419767 0.0102592446014504 0.0060149858615719 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..acb96a3fd30ac7f295e764a3c1967af1847674e3 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 118, + "title": "Average number of proteins per term", + "value": 23.296610169491526 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..700d885f3305c87c5b63deccb66e014d593454ec --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1d4896bd90116f2db1b661100b758d58351e2556 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,34 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proto-oncogene 0.4281686087923266 2.1406324171739555 0.0323036924546928 0.979240738424899 0.4235373010726401 47 P31751,O96028,Q01844,Q06136,Q5M775,Q03164,Q16204,P35637,P35658,Q15154,P22681,P46108,Q92733,Q8WY22,Q92804,P06753,P31749,Q01105 18 +Zellweger syndrome 0.9297639608520432 1.643222785277073 0.1003368472453423 0.9999961855479392 0.6119915315502178 3 O75381,P56589 2 +Osteogenesis imperfecta 0.6202689144184028 1.6296085861631973 0.1031842485551919 0.9999973758972034 0.6119915315502178 8 Q96AY3,O75718 2 +Ehlers-Danlos syndrome 0.7808270991986725 1.6031165439761073 0.1089089261054869 0.9999987674429957 0.6119915315502178 4 Q9NWM8,Q8NCH0 2 +Rhizomelic chondrodysplasia punctata 0.8791366906474811 1.5536853979894736 0.1202594778052463 0.9999997284546248 0.6450281082281396 2 O15228 1 +Peroxisome biogenesis disorder 0.7590089906910855 1.5107632570764122 0.130848779204511 0.999999934949498 0.6602022489767426 4 O75381,P56589 2 +Amyotrophic lateral sclerosis 0.4706185619950563 1.2532029425145927 0.2101318593737042 0.9999999999991844 0.6877310609566918 15 Q9NRR5,Q99720,P35637,Q13501,Q13148 5 +Retinitis pigmentosa 0.4515586902503534 1.2373776419643194 0.2159469152694608 0.9999999999996588 0.6877310609566918 18 P00846,Q8IY17 2 +Nephronophthisis 0.7965467625899264 1.2091356677329397 0.2266107281850184 0.9999999999999324 0.6877310609566918 2 Q15051 1 +Leber congenital amaurosis 0.7922302158273364 1.1912243515248409 0.2335655222150361 0.9999999999999768 0.6877310609566918 2 Q15051 1 +Primary mitochondrial disease 0.3095374898645043 1.1762702346654472 0.2394869061611348 0.9999999999999908 0.6877310609566918 98 O43676,Q70HW3,O95169,Q8N183,P00846,P14927,Q9BQT8,P22695,Q6DKK2,Q9Y2R0,O95831,Q9Y2Z9 12 +Hereditary spastic paraplegia 0.435457508326824 1.1236178902654723 0.2611751631964385 0.9999999999999996 0.7004243012995397 18 Q8IY17,O00400,Q8N0X7,O00189,P49902,Q12768,Q9H0B6 7 +FDA approved drug targets 0.2804859469184455 1.0530451252907465 0.2923203109165371 1.0 0.718620764336487 128 Q15118,Q16134,P04150,Q13423,P00374,P31939,Q9UGN5,P00813,Q16637,Q16739,P48735,P23786,P49721,Q16850,P09874,Q99720,P33527,P05067,O95749,P05771 20 +Limb-girdle muscular dystrophy 0.4877429048042052 0.9790532421764234 0.3275536730880657 1.0 0.7393202558521959 9 Q9H9S5,O14979 2 +Palmoplantar keratoderma 0.5207080215758704 0.9451184160539716 0.3445984243378879 1.0 0.7393202558521959 7 Q06136 1 +Allergen 0.6788489208633067 0.7351531163751509 0.4622462484042644 1.0 0.8140083729689871 2 O43290 1 +Deafness 0.293258029163367 0.6746992226434032 0.4998668785325995 1.0 0.8338837090430136 55 Q9NR28,Q9NWM8,O95831,P33527,Q9Y2Z9 5 +Premature ovarian failure 0.6578095840788465 0.6156034786129779 0.5381562548442227 1.0 0.8338837090430136 3 Q06787 1 +Cataract 0.3189285949572534 0.6065577379371758 0.5441444542060343 1.0 0.8338837090430136 31 P48449,O00400,P08670,O15228,Q9H444 5 +Neuronal ceroid lipofuscinosis 0.6304600657503172 0.5236700432472103 0.6005080549288637 1.0 0.8969613985013407 3 P50897 1 +Neurodegeneration 0.2377688212734675 0.3862208287621826 0.6993331291354026 1.0 0.9768122921943196 147 O60313,Q8IXJ6,Q8TD16,Q13217,O00764,O00189,Q13501,Q13148,O95831,Q12768,Q10713,O15269,Q15120,P02545,O00400,P09651,P49902,P27544,O43464,Q9Y5Y0,Q9HD42,Q9UBB4,P54802,Q6UWE0,Q9NRR5,Q16637,Q9H0B6,Q14108,Q15043,Q96D71,P35637,Q92734,O75503,P06865,Q6Y7W6,P43243,Q8IY17,Q8IV08,Q99720,Q8N0X7,Q03252,O75787,P05067,P50897 44 +Primary microcephaly 0.3316821366558308 0.3647799713931391 0.7152756569369769 1.0 0.9768122921943196 14 Q8NG31,Q86XL3,Q15058,Q8NFH4 4 +Diabetes mellitus 0.3147936677350083 0.2724822328312591 0.7852512507719984 1.0 1.0 13 P31751,Q9UKG1 2 +Williams-Beuren syndrome 0.3634005763688689 0.2362008057463498 0.8132768543106565 1.0 1.0 7 Q15056,Q9Y4P3,P35250,Q9UIG0,P78347,Q96P11 6 +Meckel syndrome 0.5191904679245045 0.2127204455107305 0.8315450185130109 1.0 1.0 3 Q15058 1 +Fanconi anemia 0.4215891220572267 0.2041582709454578 0.8382298194885622 1.0 1.0 4 Q9BXW9 1 +Tumor suppressor 0.2626624329818411 0.197491320749911 0.8434430727331501 1.0 1.0 35 P25054,Q8N163,Q9NPI1,Q53EL6,Q8N7H5,P38159 6 +Congenital muscular dystrophy 0.3871258790253772 0.1865390112174978 0.8520220891640666 1.0 1.0 5 Q9H9S5 1 +Mucopolysaccharidosis 0.3577544171194877 0.1113441284627786 0.91134346348103 1.0 1.0 5 P16278 1 +Gaucher disease 0.4376978417266142 0.0862532393308926 0.9312651094915168 1.0 1.0 2 P07602 1 +Myofibrillar myopathy 0.3637410071942399 0.0301021411930334 0.9759855930811256 1.0 1.0 2 O95817 1 +Oncogene 0.3687392055267555 0.0153260249651088 0.9877720800003924 1.0 1.0 3 O43663,Q9H8V3 2 +Primary ciliary dyskinesia 0.3518798655421353 0.0077515703504144 0.9938152036329704 1.0 1.0 3 P57076 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..50c5d00d7159ac97eff21b50a723513f0da1eab9 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pseudohermaphroditism", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCC1", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA7", "AP1B1", "AP1S1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP4M1", "APC", "APEX1", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARMC9", "ARPC1B", "ARSA", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7B", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCL10", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRD7", "BRI3BP", "BUB1B", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "C3orf58", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CAST", "CBL", "CBX2", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCT5", "CDC16", "CDC20", "CDC27", "CDC34", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CENPE", "CENPF", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHM", "CHMP1A", "CHMP2B", "CHMP4B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COASY", "COG5", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ6", "COQ8A", "COX2", "COX4I1", "COX5A", "COX6B1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREBBP", "CRK", "CRTAP", "CSDE1", 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/dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0767054f440d73879fc52366f44f5d64dabef0ca1d7c0d43614f436a447321c4 +size 88514 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..79cc76cd5e25c954ab8371eb84e13c0260ace8d2 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Metalloprotease 12 26 3.0083766952490305 0.0026264735976586 8.160194174757281 26.429611650485437 1.390302281711237 0.2661274848815638 3.192614043118206 1.543038499308978 1.1108461579919544 0.309446154241223 0.0001142889999825 0.0303491574999332 0.0181443698350236 0.000471503205235 9.357969134051989e-05 +Receptor 14 39 2.755716493305317 0.0058563733818057 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.528015530350324 0.3299370460877078 0.4328346363727663 0.567449609667859 0.5644975000974891 +Carboxypeptidase 3 6 2.401208450719179 0.0163410249034452 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0026839350013314 1.0 0.0088504827764808 0.0051503840765812 0.0049531384619904 +Rotamase 5 25 2.0524209388834023 0.0401287713158062 5.225728155339806 21.04368932038835 0.2903016415772153 0.5738010430803833 3.1033990453756255 2.0966996675039535 0.9519067598216118 0.3277712839255824 0.0002034836250707 0.0081256981844374 0.031373049189738 0.0005910649168726 0.002368909886278 +Muscle protein 2 5 1.968079837165319 0.0490588523843071 2.395631067961165 5.79126213592233 0.1338245975855889 0.4297267356278353 1.4112173151187923 1.0428309859537837 1.1380106971522683 0.3003044609278026 1.0 1.0 1.0 1.0 0.0624183143373935 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d73a39e7cb9c558968ceb3d7f9bee6e565e588e3 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 96, + "title": "Average number of proteins per term", + "value": 42.34375 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..75a37dd2bcadc5962c4ec794bc7e829ddda73a7b --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1b6ae28166fa510a049a2304dfe6b39cdb672d90 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,28 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Metalloprotease 0.6286791799634488 3.0083766952490305 0.0026264735976586 0.223122942087443 0.0280157183750257 26 P55786,O95630,O43847,O75844,P42892,Q5JRX3,Q9UIQ6,Q9BYT8,P09960,Q7Z2K6,O75976,Q9NZ08 12 +Receptor 0.521179981109732 2.755716493305317 0.0058563733818057 0.4309941488382877 0.043247064973335 39 Q9Y2W1,P24390,Q04721,O15173,Q99523,Q14108,Q99720,P30825,P04150,Q9NS69,O15118,Q8WTV0,Q9Y5Y0,O00264 14 +Carboxypeptidase 0.8573348419793023 2.401208450719179 0.0163410249034452 0.7943741768287511 0.0980461494206714 6 Q9H3G5,P42785,Q9HB40 3 +Rotamase 0.5082169645324883 2.0524209388834023 0.0401287713158062 0.980391447762209 0.1751073657417001 25 Q96AY3,O95302,Q9Y680,Q15257,Q9NWM8 5 +Monooxygenase 0.8784912179671824 2.0095185500861708 0.0444821694354833 0.9873256882628632 0.1822478695625449 4 Q16850,Q6UW02,Q9Y2Z9 3 +Muscle protein 0.8092961724788282 1.968079837165319 0.0490588523843071 0.9920062708142448 0.1883859931557395 5 P67936,Q05682 2 +Repressor 0.3214029595657195 1.7805884676797086 0.0749797051209768 0.999436983557366 0.2399350563871259 127 Q8IXH7,Q9UHX1,P18615,Q8N163,Q9UK61,Q96JN0,Q96L73,P51858,Q13148,O14979,Q14011,P49750,P62995,P38159,Q9HD42,Q96PK6,P67809,P23246,Q01844,Q5T5X7,Q9UER7,Q15233,Q8NEY8,Q13242,Q9NX63,Q71F23,Q8IZL8,Q8WXF1,Q9HCD5,Q9NYF8,P61978 31 +Porin 0.8156951058016121 1.7496583321457952 0.0801772877283402 0.999672209485818 0.2482909555458277 4 P21796,P45880 2 +Protease 0.3468094650392706 1.7060771769325829 0.0879937112771922 0.9998555252442852 0.2639811338315767 91 P67812,O43847,Q8TCT8,P42892,Q5JRX3,Q9BYT8,Q7Z2K6,Q92905,P55786,Q4J6C6,O95630,Q9HB40,Q9H8M7,Q8TCT9,O75976,Q9NQH7,Q9Y4P1,Q01804,Q9UIQ6,P42785,Q9H3G5,P28072,Q96RU2,P09960,P42575,O75844,Q16740,Q9NZ08 28 +Prenyltransferase 0.6580236243157609 1.4876716179199532 0.1368375160601811 0.999999267368836 0.3753257583364968 6 P49354,Q92696,Q9Y5Z9,Q7Z6K3,P49356 5 +Aminopeptidase 0.5231292648877326 1.3637068698999184 0.172659841024249 0.9999999874779878 0.4112075897399063 11 P55786,Q9UIQ6 2 +Dioxygenase 0.4618809235999811 1.3600820741292927 0.1738039530198669 0.9999999890357528 0.4112075897399063 19 O15460,P13674,Q9BV57,Q9UPP1 4 +Oxidoreductase 0.292568496059834 1.3149595657274995 0.1885234920176548 0.999999998047948 0.4112075897399063 171 P30519,Q16134,Q9UHG3,Q9NRG7,O95831,P13073,Q9BY49,Q9H9P8,Q9Y2Z9,O94788,P00374,Q8NBX0,Q6UW02,Q9BU89,Q15067,P30837,Q02252,Q06136,P00367,Q8N4Q0,O75845,Q96LJ7,Q15392,P48735,O15460,P09601,P13674,Q6NUM9,Q9BV57,Q16850,O75489,Q9UPP1,P36551 33 +Activator 0.3074853571493419 1.3006564671983862 0.1933760694475406 0.9999999989024462 0.4112075897399063 114 P53999,Q9Y2W1,Q8N163,P38398,P12956,Q9NYB0,Q96JN0,Q96L73,P61457,Q00577,O14979,Q8WTS6,Q14011,P62995,P38159,Q00059,Q9NPJ6,P67809,Q04721,P23246,Q15233,O15047,Q6PL18,Q9UPP1,O60869,Q9BXP5,Q8IZL8,Q8WXF1,Q9HCD5,P61978 30 +Heparin-binding 0.5894106413683378 1.290039424500841 0.1970369700837051 0.9999999992907932 0.4112075897399063 7 P05067 1 +Isomerase 0.293563222501027 0.8732057536320529 0.3825509393203288 1.0 0.667725275904574 66 Q96AY3,Q13011,O95302,Q9H7Z7,Q9Y680,Q15257,Q9NWM8 7 +Threonine protease 0.674726540011505 0.674574225847728 0.4999463127634622 1.0 0.7868007545129898 3 P28072,Q99436 2 +Serine/threonine-protein kinase 0.2731622478053738 0.6200264389552054 0.5352403805206465 1.0 0.8100721911408123 67 P31751,P51812,Q13546,O14976,Q15418,P50750,Q9BVS4,Q7KZI7,P49761,P31749,P05771 11 +Growth factor 0.4926136368954115 0.560135848016167 0.5753867804352142 1.0 0.8244347898773219 5 Q9Y3E1 1 +Translocase 0.3160426900375261 0.5049915758481599 0.613564752809143 1.0 0.834551471761869 27 P08183,Q13423,P06576,Q9HD20,P98194,P33527 6 +Glycosyltransferase 0.2980722855683013 0.4997936826371685 0.6172203593238823 1.0 0.834551471761869 34 P09874,Q13126,Q9UGN5 3 +Host cell receptor for virus entry 0.3422425097338415 0.4230155080499444 0.6722839463882839 1.0 0.8840994363462364 14 Q14108,Q8WTV0 2 +Serine protease 0.3557078099848417 0.3082381795304059 0.7579011027492868 1.0 0.9283896700481086 9 Q4J6C6,Q16740,O43464,P52948 4 +Acyltransferase 0.263141548659634 0.2291840883650719 0.8187258391249321 1.0 0.9703417352591788 41 Q00403,Q6UWP7,P35610,O15228,Q9HCL2,P23786,O60318,Q9BWD1,Q86UY6,Q8NCC3,Q92830 11 +Calcium channel 0.5064748201438808 0.1993031824568042 0.8420255898725753 1.0 0.9857860564361856 2 Q8NE86 1 +DNA-binding 0.2525011251536536 0.1494989030436362 0.8811599748854291 1.0 1.0 250 P53999,Q9UHX1,P16104,Q96B01,Q03164,P04150,P38398,P19338,P12956,Q96JN0,P51858,O95831,Q13148,O14979,Q00577,Q00403,P33991,Q04837,Q96DT7,P82970,Q9UGN5,Q9NS91,O14981,Q8ND82,Q01105,Q00059,Q2NKX8,P67809,P23246,Q9UQ84,P35637,Q5T5X7,O95983,Q9Y2U8,P61978,O43823,Q96AE4,Q92804,Q15233,Q92945,O96028,P09874,Q02818,O60869,Q969G3,P80303,Q14566,Q96I24,Q9NRG0,Q14191,Q9NYF8,P82979 52 +Developmental protein 0.2385476117176141 0.1151744562975474 0.9083068448428022 1.0 1.0 90 Q6UWP7,Q9UPN4,Q99523,Q8NB90,Q86U70,Q96EB6,P16949,Q96PU8,P31749,P31751,Q04721,O96005,Q16352,P48681,Q7KZI7,P51114,O60869,Q96EP5,Q15007 19 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f8d81e45d02906e95fbe029ba377b8a56da76188 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC1", "ABCC10", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "AMFR", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APEH", "APEX1", "APEX2", "APP", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATF7IP", "ATG3", "ATG4B", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BAZ2A", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BEND3", "BIRC6", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "CAD", "CADM1", "CALD1", "CALR", "CAMK2D", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC7", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CENPE", "CENPF", "CENPU", "CEP131", "CERS1", "CERS2", "CERS5", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHKA", "CHM", "CHMP1A", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COASY", "COLGALT1", "COMT", "COPA", "COPS5", "COQ6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRYZ", "CS", "CSDE1", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCPS", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERP44", "ESD", "ESPL1", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "F11R", "FADS2", "FAH", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLVCR1", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FRG1", "FSCN1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GIT1", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL3", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGN5", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HOXD13", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INF2", "INPP4A", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT2A", "KAT7", "KATNA1", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCMT1", "LCOR", "LDAH", "LDB1", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRFIP1", "LRSAM1", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "M6PR", "MACF1", "MAGED2", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARC1", "MARCKS", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MATR3", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED17", "MED23", "MED24", "MED4", "MEN1", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFN1", "MFN2", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MLLT1", "MMAB", "MMS19", "MOGS", "MORC2", "MORC3", "MORF4L1", "MOV10", "MPHOSPH10", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTF2", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTR", "MTSS1L", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA20", "NAA40", "NAA50", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCBP2", "NCBP3", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "ND4", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NF1", "NFS1", "NGDN", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PIGG", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP3CA", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMD9", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTAR1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD50", "RAD51AP1", "RAI1", "RALA", "RALGAPB", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RELA", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RFX1", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX2", "RIPK1", "RNASEH2A", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP14", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSBN1L", "RSF1", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHPK", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STARD9", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAOK1", "TAOK2", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM50", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TM7SF2", "TMCO1", "TMEM109", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TSFM", "TSN", "TSNAX", "TSR3", "TST", "TSTA3", "TTK", "TTLL4", "TTYH3", "TUFM", "TUT1", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBP1", "UBR2", "UBR4", "UBR5", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UROD", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP38", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP3", "UTRN", "UXS1", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VRK1", "WARS", "WARS2", "WASL", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WNK1", "WRN", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YY1", "ZADH2", "ZBED1", "ZBTB10", "ZC3H13", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZFR", "ZMPSTE24", "ZNF148", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZRANB2"], "leading_proteins": ["ABCB1", "ABCC1", "ACAT2", "ACOX1", "ADI1", "AIFM1", "AKAP8", "AKT1", "AKT2", "ALDH1A2", "ALDH1B1", "ALDH6A1", "APP", "ATAD2", "ATG4B", "ATP13A1", "ATP2C1", "ATP5B", "BCLAF1", "BEND3", "BRCA1", "BTAF1", "CALD1", "CASP2", "CCAR2", "CDK9", "CENPU", "CEP131", "CHCHD3", "CHMP1A", "CHRAC1", "CIRBP", "CLK3", "CLPP", "CLPTM1", "COPS5", "COQ6", "COX4I1", "CPD", "CPOX", "CPT2", "CPVL", "CYP20A1", "CYP51A1", "DAXX", "DAZAP1", "DHCR24", "DHFR", "DHRS1", "DOHH", "ECE1", "ECH1", "EDF1", "ERAP1", "ERCC6L", "ERMP1", "ETFDH", "EWSR1", "EXO1", "FAM208A", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FLVCR1", "FNTA", "FNTB", "FUBP1", "FUBP3", "FUS", "FXR1", "GAK", "GLUD1", "GNPAT", "GPAM", "GTF2B", "H2AFX", "HDGF", "HDGFL3", "HM13", "HMGN5", "HMOX1", "HMOX2", "HNRNPDL", "HNRNPK", "HTRA2", "IDH2", "INA", "KAT2A", "KDELR1", "KDSR", "KHSRP", "KMT2A", "L2HGDH", "LCLAT1", "LCOR", "LDB1", "LEMD3", "LNPEP", "LTA4H", "MARK2", "MBD3", "MCM3AP", "MCM4", "MCM6", "MCU", "MED4", "MINDY3", "MTAP", "NAA40", "NCL", "NCOA5", "NDUFS3", "NELFCD", "NELFE", "NES", "NLN", "NNT", "NONO", "NOTCH2", "NPC1", "NPEPPS", "NR3C1", "NRDC", "NSD1", "NSD2", "NUCB1", "NUCB2", "NUP98", "OTUD4", "P4HA1", "P4HA2", "PARP1", "PARP2", "PCBD1", "PCYOX1", "PECR", "PELP1", "PGRMC1", "PGRMC2", "PHF8", "PITRM1", "PLA2G15", "PPHLN1", "PRCP", "PREPL", "PRKCB", "PSMB6", "PSMB7", "PSPC1", "PTAR1", "PTGES2", "PTPA", "PUF60", "PURA", "QKI", "RABGGTA", "RAD18", "RAD51AP1", "RBM14", "RBMX", "RETSAT", "RIOK2", "RIPK1", "RPS6KA1", "RPS6KA3", "SARNP", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SDR39U1", "SEC11A", "SET", "SETD1A", "SETD7", "SFPQ", "SIGMAR1", "SIRT1", "SLC7A1", "SMARCE1", "SOAT1", "SORT1", "SPATA5", "SPPL2A", "SRRT", "SRSF9", "SSBP1", "STAMBP", "STMN1", "SUB1", "TAF15", "TARDBP", "TERF2IP", "TFAM", "THRAP3", "TOMM22", "TPM4", "TRA2B", "UBIAD1", "USP28", "VDAC1", "VDAC2", "WRN", "WTAP", "XPNPEP3", "XRCC6", "YBX1", "YLPM1", "ZADH2", "ZBTB10", "ZMPSTE24", "ZNF280C"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fe6da5fa354db115fd9016d740cdb1a25a67ce5c --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a53a756b22812f48f9c5f104665c814428e8c3a4 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:48b1a9dc93b49add36f2df75e5c72109b9844fb61fdb1d1c919f5150348c5c71 +size 217396 diff --git a/protein_atlas_protein_class/basic/idx2term.json 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b/protein_atlas_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14fb0e655dac9f6be443d7843b4fb0d147f55a38179bfc163bfb6f7d8b23fef0 +size 148087 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..32d472e89927e720326a0e6b773b2df40488b6fa --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d99d64116fb8a36193f2e43470f74916457d75486c4cb7216652e5687f3e05a +size 103913 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..90cd2445e405224fc158107e5f277972cf4a33b8 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 198 609 4.3432200108078405 1.4040939283699316e-05 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 0.0423045999868554 0.0908861409756165 0.0802003242312505 0.0356718160851781 0.0171472459957151 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f7064cac7a436bdb3ff88a65dd9f71715dc13f82 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 527.6666666666666 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7927f21277ad6bbc5588c1d8b32327ea27a1a69f --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0d6d6321ec2368940394f972fbef282b39adf3dd --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.3546947693494763 4.3432200108078405 1.4040939283699316e-05 0.0002948183275641 7.371493123942666e-05 609 P37268,Q99595,O60830,P30519,P00846,P42892,Q96SK2,Q93050,Q9NS69,Q07065,P42356,P04439,Q8WTV0,O75608,Q9Y2R0,O95831,Q9NQX7,P08183,Q5BJF2,Q15070,P11117,Q9HBU6,Q8NBX0,Q99808,P35610,Q9HCL2,Q02252,O15118,O43169,Q14728,Q9H4I3,P24390,P51812,O96005,O15260,Q9NR28,Q99805,P30825,Q3ZCQ8,Q9UIQ6,Q9H2J7,Q70UQ0,Q92804,Q96NB2,O14681,O43772,Q8IY17,Q9Y5Z9,Q9NWS8,O95169,Q99720,Q9UDX5,P43307,O75787,Q5T3U5,Q15629,Q9HD45,Q96G23,O75844,P33527,P05067,Q8WY22,P67812,Q6UWP7,O43676,Q8TCT8,O60725,Q86XL3,Q9UBX3,Q9HDC9,Q6UW68,Q8NCC3,Q7Z2K6,Q68DH5,O14925,Q13423,Q9BQE5,Q9Y619,Q9UPR3,Q92667,Q14534,Q8N511,Q9UI14,Q9Y5Y0,Q92575,Q06136,Q86UE4,Q8IWA4,Q9Y679,O15173,O75381,Q16739,Q15392,Q16625,O43760,P11166,Q9HD20,P09601,Q9NQG6,Q96PV6,Q8N4V1,Q15904,P18031,Q70HW3,Q8IXU6,Q9Y2G8,P56589,Q8NC44,P53985,Q6P4A7,P04035,Q8NEW0,Q9UH99,Q9Y282,Q14318,O00264,P51790,O75964,Q9Y266,Q9NX00,Q16134,Q10472,O60499,A1L0T0,Q9NR77,Q8IZA0,Q9H6V9,Q9BT22,Q13505,O15269,Q9H1E5,O00400,P41440,Q6UW02,Q9BXK5,Q8NCG7,Q8NC54,O43464,Q8NCH0,O75976,Q99590,Q9H061,Q07960,Q9C0H2,Q8WVQ1,Q9UNK0,Q9NVH0,Q14108,Q15043,Q9BZF1,Q96KC8,Q92734,P10321,Q7Z434,Q53GQ0,Q9Y3D6,O75027,Q6NUM9,Q9BU23,Q9BSK2,Q8N1F7,Q9UGP8,Q16850,Q9UH62,P36551,Q8IV08,Q6NTF9,Q9NZC3,Q9H2V7,Q5T8D3,Q8IWB1,Q96PC5,Q9P2W9,Q99523,Q96ES6,Q9UBU6,Q9P0J0,P13073,Q567V2,Q92896,P27544,Q52LJ0,Q8NHH9,Q8TCT9,Q9H9S5,Q8WVI0,O75845,Q15363,Q04721,Q9NX40,Q99567,Q9Y2U8,Q5SQN1,P98194,Q9BTX1,O00566,Q7Z3C6,Q8TBA6 198 +Predicted secreted proteins 0.3838593236945096 1.7041332150909012 0.088356202564509 0.8566727357015211 0.1958764355648082 51 O75718,Q9H6E4,Q9BTY2,Q9UMX5,Q02818,Q9UM22,Q9HB40,O60888,P05067,Q07021,Q8WUJ1,P14174,P51858,Q15165,Q9H9S5,Q9NZ08 16 +FDA approved drug targets 0.2804859469184455 1.0530451252907465 0.2923203109165371 0.9992976212632464 0.4092484352831519 128 Q15118,Q16134,P04150,Q13423,P00374,P31939,Q9UGN5,P00813,Q16637,Q16739,P48735,P23786,P49721,Q16850,P09874,Q99720,P33527,P05067,O95749,P05771 20 +Transcription factors 0.2669730804205288 0.5599171472234891 0.5755359521900572 0.9999999847011376 0.6361186839995369 68 Q03164,P04150,P17096,Q99576,Q00577,O75376,O94842,Q9H2P0,Q8ND82,Q00059,Q9UIS9,P67809,Q8WXI9,P23246,Q96KC8,Q7Z3K3,P17028,Q32MZ4,Q15233,Q86YP4,O96028,P29375,Q86U86,Q969G3,P40425,O95785,Q92922,Q8WXF1 28 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..253d44557d449bce616c081af4bad0ff0e3abfb3 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC10", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP4M1", "APC", "APEH", "APEX1", "APEX2", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC8", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD5", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "B9D1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRI3BP", "BRIX1", "BRMS1L", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C11orf98", "C12orf29", "C12orf57", "C12orf73", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf123", "C1orf198", "C1orf35", "C21orf59", "C2CD2", "C2CD5", "C2orf49", "C3orf38", "C3orf58", "C5orf15", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CENPB", "CENPE", "CENPF", "CENPI", "CENPK", "CENPM", "CENPU", "CENPV", "CEP131", "CEP170", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COIL", "COLGALT1", "COMMD2", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2L", "COX7C", "CPD", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSN1", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC8", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERICH1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM114A2", "FAM118B", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM136A", "FAM162A", "FAM192A", "FAM208A", "FAM208B", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXL18", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLVCR1", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSD1", "FTH1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAUS7", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGN5", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JCAD", "JPT2", "JUP", "KARS", "KAT2A", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNL1", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT1", "LCOR", "LDAH", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRFIP1", "LRSAM1", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP4K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED17", "MED23", "MED24", "MED4", "MEN1", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA20", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND4", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKBIE", "NFS1", "NGDN", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OFD1", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD2L", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTAR1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABAC1", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG2", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RFX1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SIRT3", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "ST7", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD7", "STARD9", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAOK2", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGS1", "THADA", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM104", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM33", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TROVE2", "TRRAP", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TUT1", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBL5", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS11", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VRK1", "VRK3", "VTA1", "WAPL", "WARS", "WARS2", "WASHC4", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR54", "WDR6", "WDR61", "WDR62", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP73", "WRN", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBED1", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF106", "ZNF148", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZNHIT2", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCC10", "ACBD5", "ACP2", "ADA", "ADNP", "AIFM1", "AKAP1", "ALDH6A1", "ALG1", "ANKLE2", "APMAP", "APOL2", "APP", "ARHGAP1", "ARMCX3", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP2C1", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "AUP1", "BCL2L13", "BRI3BP", "C1QBP", "C5orf15", "CANT1", "CCDC134", "CERS1", "CERS2", "CHST14", "CKAP4", "CLCN3", "CLPTM1", "COA3", "COX4I1", "CPD", "CPOX", "CPT2", "CRTAP", "CUTA", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DAGLB", "DHCR24", "DHFR", "DIABLO", "DNAJC1", "DNAJC16", "ECE1", "EI24", "EPDR1", "ERAP1", "ERGIC3", "ERMP1", "ETFDH", "ETNK1", "EXD2", "FAM8A1", "FAM98B", "FDFT1", "FIS1", "FKBP8", "FKRP", "FLVCR1", "FUCA2", "GALNT1", "GATAD2A", "GATAD2B", "GDE1", "GGPS1", "GLG1", "GOLGA5", "GPAM", "HDGF", "HLA-A", "HLA-C", "HM13", "HMGA1", "HMGCR", "HMOX1", "HMOX2", "HSD17B12", "HTRA2", "ICMT", "IDH2", "IKBIP", "ILVBL", "ITM2C", "ITPRIP", "KDELR1", "KDM5A", "KDSR", "KIAA0319L", "KMT2A", "LCLAT1", "LDAH", "LEMD3", "LENG8", "LMBRD2", "LMF2", "LNPEP", "LRRFIP1", "LYPLA1", "MAVS", "MBD1", "MFN1", "MFSD10", "MFSD3", "MIA2", "MIEF1", "MIF", "MMGT1", "MPHOSPH10", "MPV17L2", "MTDH", "MTFP1", "MTX1", "NCOR1", "NDC1", "NDUFA13", "NDUFB3", "NDUFB8", "NENF", "NNT", "NONO", "NOTCH2", "NPC1", "NR3C1", "NSD2", "NUCB1", "NUDC", "NUP88", "NUP93", "OCIAD1", "OCLN", "OSBPL8", "OXA1L", "PARP1", "PARP2", "PBRM1", "PBX2", "PDK1", "PEX14", "PEX3", "PGRMC1", "PGRMC2", "PI4KA", "PLA2G15", "PLD3", "PNPLA6", "POGZ", "PON2", "PRKCB", "PSMB2", "PSPC1", "PTPN1", "PURA", "PXMP2", "RABAC1", "RETREG2", "RETSAT", "RHBDD2", "RMND1", "RPS6KA3", "SC5D", "SCAF11", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SEC11A", "SEC63", "SFPQ", "SFXN2", "SFXN4", "SIGMAR1", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A33", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35F2", "SLC39A14", "SLC6A15", "SLC7A1", "SMARCC1", "SMARCE1", "SMG5", "SMIM4", "SMN1*", "SNAP47", "SOAT1", "SORT1", "SPNS1", "SPPL2A", "SPTLC1", "SQLE", "SSR1", "STX10", "STX18", "STX8", "SUN2", "SURF4", "SYNGR2", "TAF15", "TFAM", "TFG", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TM9SF2", "TM9SF3", "TMED2", "TMEM126A", "TMEM160", "TMEM199", "TMEM205", "TMEM209", "TMEM97", "TMX4", "TOMM22", "TOX4", "TRABD", "TRAM1", "TSC22D3", "TTYH3", "UBIAD1", "UBXN4", "UGCG", "WIZ", "YBX1", "ZMPSTE24", "ZNF24", "ZNF280C"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 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0.0133163568091525 5.322815533980583 14.701456310679612 0.4359129333192138 0.4564689114892047 2.679509416580786 1.5010345350043446 1.0794334084892987 0.3191667601086948 0.0607884384663988 1.0 1.0 0.0001186481206876 2.513557585079616e-07 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e564fa54e4346851ab3ca970baa257e4a2d9df9b --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3477, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 162.0 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3f8457163e8b43866c36f6245e2deea591c301f1 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C361/C361_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f2f0fd2bbcad7855a97646ad043af9fad054b3e4 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peroxisomes 0.655182576076284 2.4751946749619926 0.0133163568091525 0.3575021958829244 0.2197198873510171 16 O00116,O75521,O75381,Q15067,P56589,Q5T8D3,P40855,Q9BY49 8 +Nuclear membrane 0.3457303984832233 1.5880296149652584 0.1122796425699221 0.9803612465268312 0.6731960433704661 66 P67812,Q96SK2,O60318,Q96SY0,Q6UW68,P20700,Q9H1E5,P50402,P49790,Q5T200,P49792,Q9H8M7,P12270,O75976,P37198,Q14728,O15260,Q9Y2U8,O95619,Q9BTX1,Q86WB0,Q96G23,P57740,Q03252,Q9Y3D9,Q9UH99,A2RRP1 27 +Golgi apparatus 0.3017474061581566 1.4054127702502517 0.1598985715290826 0.9968161920384466 0.6731960433704661 188 P67812,O95302,Q8TD16,Q99523,Q93050,O60499,P35670,O15212,A1L0T0,Q9UBU6,Q8IZA0,P04439,Q99576,Q92896,P07948,Q9NW68,P25054,A4D1U4,Q9BRK5,Q14789,Q8NC54,Q86SX3,Q9HB40,P16278,Q8IYS2,O15027,Q8NCH0,Q96A49,Q8N6T3,P20340,O95070,Q9H9S5,Q8N4Q0,Q6NUQ1,Q9P289,P24390,Q8WVQ1,O15260,O14976,P53367,Q15043,Q8IWJ2,O43760,Q8N6H7,P09601,P98194,Q9BV57,O00231,O14681,Q8NEY8,Q8NEW0,Q9UH62,Q9ULU4,O43290,Q02818,Q6NTF9,Q9BSL1,P11717,Q8IXU6,Q9H2V7,P80303,P55327,Q08378,Q9NWM8,Q08379,Q9HD45,Q9HAW4,A2RRP1,P05067,P50897,Q96BK5,Q8TBA6 72 +Nucleoplasm 0.2292109121649336 0.9938400128029556 0.3203007626211283 0.9999970727903562 1.0 1360 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313 +Microtubules 0.3041016613696418 0.9001160840528997 0.3680584774121656 0.9999997355537316 1.0 61 P55209,Q8NEM2,O60830,Q02818,Q15051,Q6P2P2,P31749 7 +Nuclear speckles 0.2470181912547434 0.6154787649688765 0.5382385887888663 0.9999999999915709 1.0 139 Q9NW08,Q9Y2W1,P16104,Q96BK5,Q96SK2,Q93050,Q9ULX6,Q13123,Q96FV9,Q9BT78,Q14241,Q99576,P98175,O60828,P05387,P43490,P02545,O75400,Q92841,Q15459,O95391,P49750,O75934,Q92733,O75746,Q53F19,Q96PK6,Q9P275,O75976,Q6I9Y2,P78332,Q12874,Q9P013,Q9UBU8,Q6PJT7,Q15233,Q86VM9,O15047,Q96RT1,Q14157,Q86U42,O75600,Q96T51,O95453,O95400,Q15427,O43290,Q14191,Q9NYF8,P82979,Q15007 51 +Intermediate filaments 0.2813485203177258 0.3581022159458848 0.7202668207925986 1.0 1.0 36 O75718,P08670,Q16352,P49761,P07197 5 +Midbody 0.2896539429954254 0.1617753063019601 0.8714827995814725 1.0 1.0 15 O43663,Q8NEM2,Q9NQS7,Q9H0A0,O95785 5 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..551d8be69bd9717f4a691836f0d780140b0cd883 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APC", "APEH", "APEX1", "APEX2", "API5", "APMAP", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "ARSA", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD5", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BEND3", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRI3BP", "BRIX1", "BRMS1L", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf29", "C12orf57", "C12orf73", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf123", "C1orf198", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C3orf38", "C5orf15", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CENPB", "CENPE", "CENPF", "CENPI", "CENPU", "CENPV", "CEP131", "CEP170", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG5", "COG7", "COIL", "COLGALT1", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "CORO1B", "COTL1", "COX4I1", "COX5B", "COX6B1", "COX7A2L", "CPD", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSN1", "DSP", "DST", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERH", "ERI1", "ERICH1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM136A", "FAM162A", "FAM192A", "FAM208A", "FAM208B", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLVCR1", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA2", "GGPS1", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GIT1", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS6", "HAUS7", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HERC2", "HEXA", "HGH1", "HGS", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMGN5", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "ICE2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IER3IP1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JCAD", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFAP3", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNL1", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMTOR1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT1", "LCOR", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LIPA", "LLPH", "LMAN1", "LMBRD2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRFIP1", "LRSAM1", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "LZIC", "LZTFL1", "MACF1", "MAD2L1", "MAGED2", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED17", "MED23", "MED4", "MEN1", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MLLT1", "MMAB", "MMS19", "MMS22L", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD1", "MOSPD2", "MOV10", "MPDU1", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA20", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND4", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NF1", "NFATC2IP", "NFKBIE", "NFS1", "NGDN", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OFD1", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PBX2", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PDAP1", "PDCD11", "PDCD2L", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PM20D2", "PMAIP1", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPFIBP1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTAR1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTK2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB11FIP1", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB3B", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG2", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF114", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RPUSD2", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPK", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNTB2", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "ST7", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRIP1", "STRN", "STRN4", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAOK2", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGS1", "THADA", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM104", "TMEM109", "TMEM11", "TMEM126A", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM70", "TMEM87A", "TMEM97", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TROVE2", "TRRAP", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TTLL4", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TUT1", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS11", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "VTA1", "WAPL", "WARS", "WARS2", "WASHC4", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR46", "WDR5", "WDR54", "WDR6", "WDR61", "WDR62", "WDR70", "WDR74", "WDR77", "WDR82", "WIPI2", "WIZ", "WNK1", "WRN", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "YY1", "ZADH2", "ZBED1", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF106", "ZNF148", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AATF", "ABCB1", "ACAT2", "ACBD5", "ACOX1", "ADD1", "ADI1", "ADK", "AGPS", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALDH1B1", "AMOT", "ANAPC7", "ANGEL1", "APC", "APP", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARMCX3", "ASCC2", "ASNA1", "ATAD2", "ATG4B", "ATP2C1", "ATP6V0A1", "ATP6V1D", "ATP7B", "AUP1", "BAG6", "BCAS2", "BCLAF1", "BEND3", "BICD2", "BRCA1", "BRD7", "BRI3BP", "BRMS1L", "BSDC1", "BTAF1", "C11orf58", "C19orf70", "C2orf49", "C5orf15", "C8orf33", "CACUL1", "CANT1", "CARM1", "CASP2", "CBX5", "CCAR2", "CCDC86", "CCDC97", "CD2BP2", "CDC40", "CDCA2", "CDK9", "CDKN2AIP", "CENPU", "CERS2", "CETN2", "CHAF1A", "CHAMP1", "CHMP1A", "CHRAC1", "CHST14", "CIRBP", "CLINT1", "CLK3", "CLSPN", "COIL", "COPS4", "COPS5", "COPS8", "CPD", "CPSF7", "CPT2", "CRTAP", "CSTF2", "CWC15", "CYP20A1", "DAXX", "DAZAP1", "DCTPP1", "DDX17", "DGCR8", "DHPS", "DHRS1", "DNAJC8", "DNAJC9", "DOHH", "ECI2", "EDF1", "EI24", "EIF4H", "ELOA", "EMD", "ERAP1", "ERBIN", "ERCC6L", "ERICH1", "ESF1", "ESS2", "ETNK1", "EWSR1", "EXO1", "FAM208A", "FAM208B", "FAM49B", "FAM50A", "FAM8A1", "FAM98B", "FANCD2", "FIP1L1", "FKBP14", "FKBP9", "FKRP", "FN3KRP", "FUBP1", "FUBP3", "FUS", "GADD45GIP1", "GAK", "GCAT", "GCC2", "GDE1", "GGPS1", "GINS4", "GLB1", "GLG1", "GNL3L", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GTF2B", "GTF2E1", "H2AFX", "HDGF", "HDGFL2", "HDGFL3", "HEATR3", "HEBP1", "HLA-A", "HMGN5", "HMOX1", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPUL2", "IGF2R", "IK", "ILVBL", "INA", "INCENP", "INTS13", "INTS14", "IQCB1", "IWS1", "KDELR1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA2013", "KIF18B", "KIF20A", "KLC2", "KMT2A", "KNL1", "KPNA2", "LAS1L", "LCOR", "LDB1", "LEMD3", "LENG8", "LMBRD2", "LMNA", "LMNB1", "LMNB2", "LRRC41", "LSM3", "LTA4H", "LTV1", "LYN", "LYPLA1", "MARCKS", "MARK2", "MATR3", "MBD3", "MCM3AP", "MCM4", "MCM6", "MED4", "MFAP1", "MFSD10", "MICU2", "MIF", "MINDY3", "MORF4L1", "MRFAP1", "MRPS23", "MTAP", "MTBP", "NAA35", "NAA40", "NAF1", "NAMPT", "NAP1L1", "NAP1L4", "NASP", "NAT10", "NBAS", "NCBP3", "NCL", "NCOA5", "NDC1", "NEFM", "NELFCD", "NELFE", "NFATC2IP", "NOC4L", "NONO", "NOTCH2", "NPC1", "NR3C1", "NRDC", "NSD1", "NSD2", "NSFL1C", "NSUN2", "NT5DC1", "NUCB1", "NUCB2", "NUCKS1", "NUFIP2", "NUP107", "NUP153", "NUP37", "NUP62", "NUP88", "NUPL2", "PABPN1", "PAF1", "PARN", "PARP1", "PARP2", "PBDC1", "PCBD1", "PCNP", "PDCD4", "PDCD5", "PDCL3", "PDS5A", "PDS5B", "PECR", "PEF1", "PELP1", "PEX14", "PEX19", "PEX3", "PFDN6", "PGM3", "PHAX", "PHF14", "PHF3", "PHF8", "PI4KA", "PINX1", "PIP4K2C", "PLA2G15", "PNO1", "POLR2E", "POLR3B", "PPHLN1", "PPT1", "PQBP1", "PRC1", "PRCC", "PRKCB", "PRMT9", "PRPF39", "PRPF40A", "PSIP1", "PSMB2", "PSMB4", "PSMB6", "PSMD11", "PSME2", "PSME3", "PSPC1", "PTPA", "PUF60", "QKI", "RAB6A", "RAD18", "RAD51AP1", "RANBP2", "RANBP3", "RAVER1", "RBM10", "RBM12B", "RBM14", "RBM17", "RBM3", "RBM4", "RBM5", "RBM6", "RBMX", "RBMXL1", "RECQL4", "RHBDD2", "RINT1", "RNF20", "RNF219", "RNF40", "RPLP2", "RPS6KA1", "RPS6KA3", "RPUSD2", "RRP15", "RRP36", "RUFY1", "SAAL1", "SAMHD1", "SARNP", "SART1", "SC5D", "SCPEP1", "SDF4", "SDR39U1", "SEC11A", "SEC16A", "SET", "SETD1A", "SF1", "SF3A1", "SF3A3", "SF3B4", "SFPQ", "SFXN4", "SGTA", "SHCBP1", "SIRT1", "SIRT2", "SLC25A10", "SLC25A12", "SLC30A7", "SLC35F2", "SLC39A14", "SLU7", "SMARCE1", "SMC6", "SMIM4", "SMNDC1", "SMYD3", "SNAP29", "SORT1", "SPECC1", "SPNS1", "SRRT", "SRSF1", "SRSF10", "SRSF2", "SRSF9", "STAMBP", "STK26", "STX10", "SUB1", "SUGP1", "SUN2", "SURF4", "SYAP1", "SYNCRIP", "SYNGR2", "TAF15", "TARDBP", "TEDC1", "TERF2IP", "TFIP11", "THOC1", "THOC7", "THRAP3", "TIAL1", "TIMM17A", "TIMM17B", "TIMM50", "TM9SF3", "TMEM126A", "TMEM205", "TMEM209", "TMX4", "TPD52", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRIR", "TSC22D3", "TSR2", "UBAC1", "UBAP2L", "UBE2Q1", "UBQLN4", "UPF3B", "USP28", "USP36", "VIM", "VRK3", "WAPL", "WASHC5", "WBP11", "WIZ", "WRN", "WTAP", "XRCC6", "YEATS4", "YIF1A", "YLPM1", "ZADH2", "ZBTB10", "ZC3H13", "ZC3H14", "ZC3H18", "ZC3HC1", "ZMYND8", "ZNF280C"]} \ No newline at end of file