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58c1272 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Interconversion of nucleotide di and triphosphates 0.7139517985175867 2.5507978088127405 0.0107476657185645 0.9999997337900464 0.9546537734989116 18 Q9H773 1
Complex i biogenesis 0.7490759319649049 2.477364739283507 0.0132356566015561 0.9999999921829922 0.9546537734989116 27 Q9NPL8,Q9Y6M9,O43674,O95139,O96000,O75380,P03886,Q16795,O95182,O95168,O75306 11
Piwi interacting rna pirna biogenesis 0.7749844494146654 2.3599872144605465 0.0182755649187789 0.99999999999401 0.9546537734989116 9 Q9Y2W6 1
Transcriptional activation of mitochondrial biogenesis 0.6311782974565898 2.0709951629996364 0.0383592480836592 1.0 0.9546537734989116 15 P48735,Q96RR1,O00411,O75376 4
Miscellaneous transport and binding events 0.7960631051382318 2.068147816044873 0.038626125550653 1.0 0.9546537734989116 7 Q8N4V1 1
Metabolism of cofactors 0.7878412644337214 2.0327623854550536 0.0420765350450191 1.0 0.9546537734989116 7 P35270,O75874 2
Condensation of prometaphase chromosomes 0.6713089617976754 1.9870876869455296 0.0469126804955535 1.0 0.9667273407775356 11 P06493,P14635,P19784,Q9BPX3,P67870,P68400,O95067,Q15003 8
Transport of vitamins nucleosides and related molecules 0.7372185060478113 1.987005274001564 0.0469218124003372 1.0 0.9667273407775356 8 P12236,Q99808,P12235,O00400,P05141 5
Sphingolipid de novo biosynthesis 0.6488383846304396 1.9391990216996835 0.052477108703838 1.0 1.0 12 Q9NRA0,Q96G23,O95470,Q9P0L0,Q06136,O15121,P51648 7
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.7971956139825863 1.9059623943443635 0.0566550848525575 1.0 1.0 6 P11310,Q16836 2
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.8197588944428073 1.9040984963875889 0.0568973575107283 1.0 1.0 5 Q99808,P12235,P12236,P05141 4
Beta oxidation of decanoyl coa to octanoyl coa coa 0.8128903977198503 1.8760713766952564 0.0606454794767055 1.0 1.0 5 P11310,Q16836 2
Beta oxidation of octanoyl coa to hexanoyl coa 0.8128903977198503 1.8760713766952564 0.0606454794767055 1.0 1.0 5 P11310,Q16836 2
Circadian clock 0.6355250906788121 1.8695778041887496 0.0615424699138127 1.0 1.0 12 P43490 1
Nr1h2 and nr1h3 mediated signaling 0.7450929611801844 1.8467220843771504 0.0647874292839145 1.0 1.0 7 O00767,Q8NB78 2
Phosphorylation of emi1 0.8111234426446843 1.7764611934140522 0.0756569327038654 1.0 1.0 4 P53350,Q12834 2
Miro gtpase cycle 0.8068783068783089 1.7592454724438424 0.0785358237468303 1.0 1.0 4 O95140,Q8IWA4,Q8IXI2 3
Triglyceride metabolism 0.7234704525732204 1.7513679836358278 0.0798825442059614 1.0 1.0 7 Q9HCL2 1
Signalling to ras 0.8015873015873058 1.7377565435351552 0.0822537208339142 1.0 1.0 4 Q16539,P11234,P11233 3
Polo like kinase mediated events 0.775079749932827 1.7205470871764612 0.0853330421604261 1.0 1.0 5 P14635,P53350,P49454 3
Cholesterol biosynthesis 0.5552580667320884 1.7197743928394529 0.0854734590466252 1.0 1.0 16 P04035,Q03426,O75845,Q16850,Q15738,Q15392,Q14739,P48449 8
Beta oxidation of lauroyl coa to decanoyl coa coa 0.793295422229537 1.704010791883586 0.0883790710985508 1.0 1.0 4 Q16836 1
Beta oxidation of hexanoyl coa to butanoyl coa 0.793295422229537 1.704010791883586 0.0883790710985508 1.0 1.0 4 Q16836 1
Synthesis of pa 0.6344229938688045 1.6796738718184996 0.0930207860914644 1.0 1.0 9 Q9NUQ2,Q8NAN2,Q9HCL2,Q86UL3 4
Activation of gene expression by srebf srebp 0.568825948428144 1.6738837644460336 0.0941534455960368 1.0 1.0 20 Q16850,O00767,Q9HCL2,P48449 4
Gamma carboxylation hypusine formation and arylsulfatase activation 0.6206467104327213 1.6668646916708032 0.0955413131250078 1.0 1.0 10 Q9HA64 1
Activation of nima kinases nek9 nek6 nek7 0.7571048708741286 1.645930746336895 0.099778017949069 1.0 1.0 5 Q8TD19,P14635,P53350 3
Hdms demethylate histones 0.6127082510022822 1.6262815370950443 0.1038897775516289 1.0 1.0 10 P62805,Q8NHM5,Q8NB78 3
Carnitine metabolism 0.726921661443597 1.6110123655541873 0.1071770272982601 1.0 1.0 6 P23786,O43772 2
Mitochondrial fatty acid beta oxidation 0.5363197351968794 1.6087312204782267 0.107675125983069 1.0 1.0 16 P05165,Q96CM8,Q16836,P40939,P11310,P05166 6
Synaptic adhesion like molecules 0.7207506309344937 1.5847784917665158 0.1130166708182631 1.0 1.0 6 P41440 1
Citric acid cycle tca cycle 0.5409402067215273 1.5729197082461783 0.1157374110092885 1.0 1.0 18 P21912,O75390,P48735,O43837,P31040,Q02218,P23368 7
Synthesis of pg 0.8681198320841836 1.5477937949609677 0.1216719509237687 1.0 1.0 3 Q32NB8 1
Homologous dna pairing and strand exchange 0.5502030723296254 1.5427898038160346 0.1228817841805443 1.0 1.0 14 P35244,Q9UQ84,O60934,P54132 4
Hdr through single strand annealing ssa 0.5502030723296254 1.5427898038160346 0.1228817841805443 1.0 1.0 14 P35244,Q9UQ84,O60934,P54132 4
Inhibition of dna recombination at telomere 0.5612841759444829 1.5374490313362352 0.1241833872945674 1.0 1.0 13 P62805,P52434,P84243 3
Beta oxidation of butanoyl coa to acetyl coa 0.8509108530253715 1.482717474478017 0.1381494898930371 1.0 1.0 3 Q16836 1
Integrin cell surface interactions 0.7368627115858969 1.4724053797555827 0.1409114412838952 1.0 1.0 4 Q08722 1
Alpha oxidation of phytanate 0.7301122643156097 1.4445182642491703 0.1485932459102739 1.0 1.0 4 O43808,P51648 2
Defects in vitamin and cofactor metabolism 0.5842547277906335 1.426776378157239 0.1536443620575673 1.0 1.0 9 Q96RQ3,Q96EY8,P05166,P11498 4
Slc mediated transmembrane transport 0.5344510910164765 1.4148534455152988 0.1571114701122982 1.0 1.0 22 P12236,Q9Y6M7,Q99808,P12235,O00400,P05141,Q9UBX3,Q9H936,P55011,P53985 10
Signal regulatory protein family interactions 0.7212722237026543 1.407957160302234 0.1591437556500829 1.0 1.0 4 Q08722 1
Mismatch repair 0.5594760265209251 1.4062863538009918 0.1596391106442527 1.0 1.0 11 Q9UQ84 1
Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0.7202495777566831 1.4037249559876008 0.1604007680667303 1.0 1.0 4 P11310,P40939 2
Receptor mediated mitophagy 0.7145796590241089 1.3802512588903249 0.1675092964899946 1.0 1.0 4 Q96HS1,P68400,P19784 3
Peroxisomal lipid metabolism 0.5418914004242431 1.3699866739318227 0.1706910615392349 1.0 1.0 12 O43808,Q15067,P51648 3
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6907184992610593 1.367391799999952 0.1715025311937381 1.0 1.0 5 Q8NB78 1
Class i peroxisomal membrane protein import 0.5552897191890098 1.329943890632749 0.1835367588727465 1.0 1.0 10 O43808,Q8TB36 2
Activation of ppargc1a pgc 1alpha by phosphorylation 0.8055302054044386 1.3106843121524316 0.1899644409727066 1.0 1.0 3 Q16539 1
P38mapk events 0.8016456068175014 1.2959527322674431 0.1949917701302383 1.0 1.0 3 P11233,Q16539 2
Gab1 signalosome 0.7999188679755107 1.2894051658079713 0.1972572664508756 1.0 1.0 3 Q06124 1
Resolution of d loop structures 0.6191083962262189 1.281946801302969 0.1998613086985616 1.0 1.0 7 Q9UQ84,P54132 2
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.6191083962262189 1.281946801302969 0.1998613086985616 1.0 1.0 7 Q9UQ84,P54132 2
Hdr through homologous recombination hrr 0.5191789030108606 1.269592125838742 0.2042299556896454 1.0 1.0 24 O60934,Q9UQ84,Q9NR33,P35244,P54132,Q07864,P41440 7
Aspartate and asparagine metabolism 0.6670451928213657 1.2673590430286978 0.2050269375794347 1.0 1.0 5 P08243,O75746 2
E3 ubiquitin ligases ubiquitinate target proteins 0.4760498883465629 1.2529107931336017 0.2102381734973657 1.0 1.0 16 Q9GZS3,Q9BUN8 2
Interferon gamma signaling 0.5299320651972395 1.2499312549785608 0.211324660843275 1.0 1.0 11 P19474 1
Glutamate and glutamine metabolism 0.5803090999444654 1.2466093127347972 0.2125407853616547 1.0 1.0 8 Q96C36,P32322,P00367 3
Depolymerisation of the nuclear lamina 0.532308789920611 1.2105660165942216 0.2260617751951521 1.0 1.0 10 P50402,P14635,P42167 3
Translesion synthesis by polk 0.5307987535819416 1.2027211848151314 0.2290842330811977 1.0 1.0 10 P41440 1
Flt3 signaling 0.6716894228873667 1.2024617744973538 0.2291846676603448 1.0 1.0 4 Q06124 1
Golgi cisternae pericentriolar stack reorganization 0.5063266326185525 1.17790104032526 0.2388360603059431 1.0 1.0 12 P14635,Q9H0U4,O95067,P62820,P53350 5
Mitochondrial trna aminoacylation 0.4707825313079575 1.156448332297484 0.2474978217845853 1.0 1.0 15 Q9Y2Z4,Q6PI48,P26640,Q9NSE4,Q9NP81,Q5ST30,Q9BW92,Q5T160,Q5JPH6,Q15031 10
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.7560975609756101 1.12364393846379 0.2611641081829456 1.0 1.0 3 Q13547,P20248 2
Phase i functionalization of compounds 0.4753433479169023 1.1213313498353377 0.2621468458788167 1.0 1.0 14 Q6QHF9,P05091,Q16850,O43169,Q5VT66 5
Regulation of cholesterol biosynthesis by srebp srebf 0.4963916430881226 1.0854536877872842 0.2777207649120019 1.0 1.0 26 Q16850,O00767,Q9HCL2,P48449 4
Defects in biotin btn metabolism 0.6039123801544066 1.0826146452557703 0.2789795040396789 1.0 1.0 6 Q96RQ3,P05166,P11498 3
Tp53 regulates transcription of cell death genes 0.5461492572672013 1.0824883789744535 0.2790355763873737 1.0 1.0 8 P55212,Q07812 2
Translesion synthesis by polh 0.4758514849341136 1.0671657278921969 0.2858970056349013 1.0 1.0 13 P41440 1
Visual phototransduction 0.5647530766535032 1.035092851460848 0.3006255506872621 1.0 1.0 7 Q6NUM9,P17252,P53582,P29375 4
Recognition of dna damage by pcna containing replication complex 0.4516389439689132 1.0220090086015312 0.3067766366901239 1.0 1.0 19 P41440,Q9NR33 2
Condensation of prophase chromosomes 0.5039057620084778 1.0175874504741225 0.3088740537515142 1.0 1.0 9 P14635,P53350,P84243 3
Termination of translesion dna synthesis 0.455179150987381 1.0141956716872045 0.310489393540911 1.0 1.0 20 Q15004,Q9NR33,P35244,Q07864,P41440 5
Beta oxidation of very long chain fatty acids 0.6028020548176432 0.9964899720741796 0.3190121370083338 1.0 1.0 5 Q15067 1
Propionyl coa catabolism 0.7220099911842309 0.9958661840150194 0.3193151676498575 1.0 1.0 3 P05165,P05166 2
G2 m dna replication checkpoint 0.6171819795509932 0.9777321504065748 0.3282068162106473 1.0 1.0 4 O95067,P14635 2
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.5512004318382919 0.9739122330925484 0.3301001192056998 1.0 1.0 7 Q15067,O95864 2
Eukaryotic translation elongation 0.6564616670025729 0.9708794471283464 0.331608314020487 1.0 1.0 77 P46777,Q07020,P61353,P36578,P84098,P39023,P62910,P62081,P47914,P61927,P62829,P62857,P83881,P15880,P62851,Q02543,P62750,P61254,P62854,P18621,P49207,P08708,P50914,P27635,P61313,P32969,P62263,P26373,P30050,P46779,P18124,P62753,P62266,P83731,P60866,P61247,P62906,Q02878,P46781,P26641,P46782,P42766,P62701,P62277,P40429,P62424,P62269,P62241,P62847,P62917,P62913,P46776 52
Wnt mediated activation of dvl 0.7143696738172205 0.9674612431132494 0.3333135070365389 1.0 1.0 3 P19784,P68400 2
Vxpx cargo targeting to cilium 0.4758969223849723 0.9651104563894533 0.3344894901717783 1.0 1.0 11 Q9NV70,Q8TAG9 2
Nuclear receptor transcription pathway 0.7129424349287974 0.9621669022508552 0.3359657719451803 1.0 1.0 3 O75376 1
Transport of inorganic cations anions and amino acids oligopeptides 0.4737492024604841 0.9539065826650798 0.340130931116775 1.0 1.0 11 Q9UBX3,Q9H936,Q9Y6M7 3
Egr2 and sox10 mediated initiation of schwann cell myelination 0.4910390514339194 0.9525135251020476 0.3408366099563527 1.0 1.0 9 Q16850,Q14118,P07942 3
Response of eif2ak4 gcn2 to amino acid deficiency 0.6491251909573642 0.9460450296388428 0.3441256194141004 1.0 1.0 76 P46777,Q07020,P61353,P36578,P84098,P39023,P62910,P62081,P47914,P61927,P62829,P62857,P83881,P15880,P62851,Q02543,P62750,P61254,P62854,P18621,P08708,P49207,P50914,P61313,P27635,P32969,P62263,P26373,P30050,P46779,P18124,P62753,P08243,P62266,P83731,P60866,P62906,P61247,Q02878,P46781,P46782,P42766,P62701,P40429,P62277,P62424,P62269,P62241,P62847,P62917,P62913,P46776 52
Gap filling dna repair synthesis and ligation in gg ner 0.4431129468029577 0.9457707874180266 0.3442655084482027 1.0 1.0 20 P41440,Q9NR33 2
Pcna dependent long patch base excision repair 0.4422562126332698 0.94094267181122 0.346734238399903 1.0 1.0 20 P41440,Q9NR33 2
Defects in cobalamin b12 metabolism 0.7046387108084821 0.9314441809319814 0.3516238459678242 1.0 1.0 3 Q96EY8 1
Cobalamin cbl vitamin b12 transport and metabolism 0.7046387108084821 0.9314441809319814 0.3516238459678242 1.0 1.0 3 Q96EY8 1
Trna modification in the mitochondrion 0.5663318097166675 0.9217500006463246 0.3566589930826085 1.0 1.0 6 Q969Y2,O75648,Q9Y606 3
Respiratory electron transport 0.5621909002686938 0.9080385229425312 0.3638578689641074 1.0 1.0 50 P31930,Q9BSH4,Q9NPL8,Q9Y6M9,O75880,O95139,O96000,O75380,O00483,P03886,Q16795,O95168,O95182,O43674,O75306 15
Glyoxylate metabolism and glycine degradation 0.4809791785947984 0.9019152055081008 0.3671019133423896 1.0 1.0 9 P09622,P10515,Q9UBQ7,Q02218,P08559,P11182 6
Telomere c strand synthesis initiation 0.5762597329272627 0.886011258513456 0.3756114604111564 1.0 1.0 5 P49642,Q15554 2
Base excision repair ap site formation 0.5756411121759777 0.8834547148869194 0.3769906396388043 1.0 1.0 5 P62805,P13051 2
Downstream signaling of activated fgfr2 0.6915197434455032 0.8832136831246615 0.377120830002003 1.0 1.0 3 Q06124 1
Downstream signaling of activated fgfr1 0.6915197434455032 0.8832136831246615 0.377120830002003 1.0 1.0 3 Q06124 1
Downstream signaling of activated fgfr4 0.6915197434455032 0.8832136831246615 0.377120830002003 1.0 1.0 3 Q06124 1
Downstream signaling of activated fgfr3 0.6915197434455032 0.8832136831246615 0.377120830002003 1.0 1.0 3 Q06124 1
Meiotic recombination 0.4409695629678214 0.8783554104014772 0.379750874290885 1.0 1.0 13 O60934,P84243,P62805,P35244,P54132 5
Dscam interactions 0.687628563032598 0.8689888880247499 0.3848532086520526 1.0 1.0 3 P63000,Q16539 2
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4417639767880758 0.859186897971508 0.3902374107123627 1.0 1.0 23 Q15004,P15927,Q9NR33,Q92890,P35244,Q07864,P41440 7
Mitochondrial biogenesis 0.5060801012097933 0.8542949772409222 0.3929415694977081 1.0 1.0 38 P48735,Q96RR1,O75964,Q16539,P24539,O75376,O00411,Q6UXV4,P17152,P00367 10
Sirt1 negatively regulates rrna expression 0.5833544572750639 0.8406786224516909 0.4005279997703193 1.0 1.0 4 P84243 1
Metabolism of folate and pterines 0.4677927572143003 0.8360831841534423 0.4031081077575453 1.0 1.0 9 P34896,P41440,Q9H2D1 3
Diseases associated with n glycosylation of proteins 0.4933803140032374 0.831925618367885 0.4054509305238223 1.0 1.0 8 Q96AA3 1
Polymerase switching on the c strand of the telomere 0.4123520740498868 0.8271273698403737 0.4081648725690434 1.0 1.0 15 P09884,P49642,P28340,Q15554,P35251,P41440 6
Glycerophospholipid biosynthesis 0.4836749083273003 0.8232972645960327 0.4103389687949503 1.0 1.0 34 Q8NAN2,Q9HCL2,Q8NCC3,Q99943,Q96N66,Q86UL3,Q9NUQ2,P40939,Q9NQZ5,O95674,O14735,Q92604,Q32NB8 13
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.465134697116801 0.8228936480621769 0.4105684751760885 1.0 1.0 9 P14635,Q07812,O14965 3
Signaling by ntrk2 trkb 0.5593589265985821 0.8165481890827786 0.4141866740035125 1.0 1.0 5 Q06124,P62993 2
Loss of function of mecp2 in rett syndrome 0.5159264580224002 0.8164959289249706 0.4142165509986437 1.0 1.0 7 P17612,Q13547,O75376 3
Peptide hormone metabolism 0.4095827994822428 0.8119929077151085 0.4167957011029095 1.0 1.0 15 P67812,Q9NV70,Q8TAG9 3
Protein protein interactions at synapses 0.404310094273895 0.8102191207818561 0.4178142499249109 1.0 1.0 17 P41440 1
Mitochondrial translation 0.5623390834149532 0.8036937206450164 0.4215738815140597 1.0 1.0 56 P82912,P51398,P49406,Q15070,Q6P1L8,Q9Y2R5,Q9BYD1,Q9P0M9,Q9BZE1,Q9Y3B7,Q7Z2W9,Q9NP92,P82663,P82914,Q9Y399,Q92552,P46199,Q8N983,Q96DV4,Q14197,P82675,P09001,Q9BRJ2,Q9Y3D3,Q9NX20,O75616,Q9HD33,Q9NYK5,Q9BYD2,Q9P015,P82930,O15235,Q9Y2Q9 33
Ketone body metabolism 0.6664690247060017 0.7923898122003925 0.4281334179126168 1.0 1.0 3 P35610 1
Synthesis of ketone bodies 0.6664690247060017 0.7923898122003925 0.4281334179126168 1.0 1.0 3 P35610 1
Netrin 1 signaling 0.450147767187112 0.7890491592029503 0.430083275068799 1.0 1.0 10 P63000,Q06124,Q16539 3
Mitophagy 0.4329729449741599 0.7886807232915112 0.4302986373150381 1.0 1.0 12 O95140,P19784,P68400,P67870,Q8IWA4,Q96HS1 6
E2f enabled inhibition of pre replication complex formation 0.5093159485438803 0.7874128428934211 0.4310402310476724 1.0 1.0 7 Q9Y619 1
Synthesis of very long chain fatty acyl coas 0.4555929128484688 0.7758075031466635 0.4378626530954359 1.0 1.0 9 Q4G176 1
E2f mediated regulation of dna replication 0.4189255213965791 0.7621440082802619 0.4459740595881121 1.0 1.0 13 P06493,P09884,P49642,P14635,Q9Y619 5
Biotin transport and metabolism 0.4983888575083583 0.7397225276627285 0.4594683758810154 1.0 1.0 7 Q96RQ3,P05166,P11498 3
Regulation of lipid metabolism by pparalpha 0.4230303159042902 0.7342265814155464 0.4628106555168054 1.0 1.0 24 Q71SY5,P23786,Q9ULK4,P11310,O75376,O75192,Q15067 7
Gluconeogenesis 0.402120690697845 0.7209845491900261 0.4709190210437242 1.0 1.0 20 Q9UBX3,Q02978,P53007,O75746 4
Organic anion transporters 0.8819036427732034 0.7188938212144499 0.4722063437798947 1.0 1.0 2 Q9UBX3 1
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.4143785545552652 0.7127468372407763 0.4760024279677837 1.0 1.0 23 P41440,Q9NR33 2
Tp53 regulates transcription of cell cycle genes 0.3957359825529816 0.7119874761233561 0.4764725313333859 1.0 1.0 19 P14635,O95628,P20248,Q9UKZ1,Q07812,O14965,A5YKK6 7
Initiation of nuclear envelope ne reformation 0.3900683009403908 0.7069485805088972 0.4795984324979616 1.0 1.0 18 P50402,P14635,Q8NC56,P42167,Q99986,O95067,Q14739 7
Processing of dna double strand break ends 0.4304197812232696 0.7032884358159937 0.4818760159504482 1.0 1.0 27 O60934,P15927,Q9UQ84,P20248,P62805,P35244,P54132 7
Dna replication initiation 0.4645957977444843 0.6990936370298387 0.4844935147718492 1.0 1.0 8 P49642,Q9NR33,Q07864 3
Cyclin a b1 b2 associated events during g2 m transition 0.4152298386398692 0.6984376577612096 0.4849035327914324 1.0 1.0 12 O95067,P14635,P53350,P20248 4
Inactivation of cdc42 and rac1 0.6379665001469146 0.6916599300259628 0.4891509163008216 1.0 1.0 3 P60953,P63000 2
Fanconi anemia pathway 0.4854445680365137 0.6839474637654616 0.4940083409663371 1.0 1.0 7 P15927,P35244,Q16658 3
Resolution of abasic sites ap sites 0.4308919483836516 0.6835370952572547 0.494267518282993 1.0 1.0 28 P13051,P41440,Q9NR33 3
Telomere c strand lagging strand synthesis 0.4041119759786713 0.6831375994230184 0.4945198985677179 1.0 1.0 22 P49642,P15927,Q15554,P35244,P54132,P41440 6
Cellular responses to stimuli 0.2398029434116914 0.6757923010057942 0.4991725235158488 1.0 1.0 339 P28074,O75880,O43819,P61353,P49721,O43242,P15880,P28070,P62851,Q00534,P49207,P62263,Q96L91,P60866,P61247,Q02878,Q9BSH4,O60934,P20618,P15927,P62424,Q9BTX1,O95429,P62917,Q07020,P36578,P62910,P47914,Q02543,P35244,P62854,P50914,O00233,Q8N122,Q9NQT4,P84243,P46779,P18124,P62753,P62266,O00483,P83731,P46781,O95070,Q16539,P62277,P62241,P60900,Q9NZ32,P84098,P39023,O75376,P10412,P18621,P08708,P27635,Q6IAA8,P26373,P62805,P62906,P42766,Q15554,P40429,Q9UJW0,P46776,P62081,P61927,P00390,Q16763,P62750,P61254,P61313,P32969,P08243,P62701,Q13309,P62269,P78406 78
The phototransduction cascade 0.5379185998572723 0.6625334316865793 0.507629416466302 1.0 1.0 4 P17252,P53582 2
Insulin processing 0.4239790232542745 0.660437873537436 0.508972874413522 1.0 1.0 10 Q9NV70,Q8TAG9 2
Nonsense mediated decay nmd 0.6139787449821715 0.6600970419790918 0.5091915568199237 1.0 1.0 86 P46777,Q07020,P61353,P36578,P84098,P39023,P62910,Q9NPI6,P62081,P47914,P61927,P62829,P62857,P83881,P15880,P62851,Q02543,P62750,P61254,P62854,P18621,P49207,P08708,P50914,P27635,P61313,P32969,P62263,P26373,P30050,P46779,P18124,P62753,P62266,P83731,P60866,P61247,P62906,Q02878,P46781,P46782,P42766,P62701,P62277,P40429,P62424,Q9HAU5,P62269,P62241,P62847,P62917,P62913,P46776 53
Raf independent mapk1 3 activation 0.4797816831284157 0.6598276897543016 0.5093644118717189 1.0 1.0 7 P06493,Q99956,Q06124 3
Rna polymerase i promoter escape 0.3713301770140583 0.6582001893564717 0.510409503159365 1.0 1.0 16 P62805,P52434,P84243 3
Dna damage bypass 0.410128127781465 0.645236901305955 0.5187736760702073 1.0 1.0 25 Q15004,P15927,Q9NR33,Q92890,P35244,Q07864,P41440 7
Regulation of runx1 expression and activity 0.6238477972856472 0.6430510450051028 0.5201909786214745 1.0 1.0 3 Q06124 1
Cd28 dependent vav1 pathway 0.5152383470189769 0.6402529319739145 0.522008175415821 1.0 1.0 5 P60953,P63000,P62993 3
Assembly of the orc complex at the origin of replication 0.4191089452467167 0.6370519234742744 0.5240910227101294 1.0 1.0 10 Q9Y619,P84243 2
Platelet sensitization by ldl 0.4716431673243884 0.6254995266085418 0.5316432590124598 1.0 1.0 7 Q06124 1
Dual incision in gg ner 0.4007252311412903 0.6204790700170096 0.5349424294552543 1.0 1.0 24 Q9NR33,P35244,Q07864,Q92759,P41440 5
Mapk3 erk1 activation 0.5258419728195636 0.6168447901723939 0.5373371055755696 1.0 1.0 4 Q06124 1
Nrage signals death through jnk 0.4688906578438457 0.6139855190586846 0.5392248963943829 1.0 1.0 7 P63000,Q14344,Q14155 3
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.507522198883452 0.6104187036545613 0.5415844813973734 1.0 1.0 5 P84243 1
Processive synthesis on the c strand of the telomere 0.3972909740203044 0.6099417380163449 0.5419004027003846 1.0 1.0 12 P35244,Q15554,P54132 3
Dna methylation 0.5052848989561559 0.601835986645983 0.5472833180470382 1.0 1.0 5 P62805,P84243 2
Cytosolic sensors of pathogen associated dna 0.3829572865292509 0.5990781687990089 0.5491207590153109 1.0 1.0 21 P52434,P19474,Q9H1D9 3
Lagging strand synthesis 0.3762983378867626 0.5885922594018328 0.5561348277023876 1.0 1.0 20 P41440 1
Energy dependent regulation of mtor by lkb1 ampk 0.407305950889314 0.5812465580124402 0.5610742931091 1.0 1.0 10 Q6IAA8,Q8N122,P54646 3
Maturation of sars cov 2 spike protein 0.3906635168158525 0.5780936261404063 0.563200910073592 1.0 1.0 12 Q9H0U3,P46977 2
Oas antiviral response 0.6032912136350286 0.5741223719116951 0.5658849952849292 1.0 1.0 3 Q6L8Q7,P61221 2
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5278639104429433 0.5674837845249344 0.5703855404183873 1.0 1.0 61 P31930,Q9BSH4,Q9NPL8,O75964,Q9Y6M9,O75880,P24539,O95139,O96000,O75380,O00483,P03886,Q16795,O95168,O95182,O43674,O75306 17
Cristae formation 0.3742602505609111 0.5565966094067425 0.5778030708735686 1.0 1.0 21 Q6UXV4,P17152,P24539 3
Non integrin membrane ecm interactions 0.4317774713576934 0.5537157929801132 0.5797733652075745 1.0 1.0 8 O14936,Q14118,P07942 3
Apc c cdc20 mediated degradation of cyclin b 0.377026876654305 0.552855604895983 0.5803622892184006 1.0 1.0 13 P14635,Q12834 2
Selenoamino acid metabolism 0.5950379684518005 0.5491092334955726 0.5829304889808751 1.0 1.0 89 P46777,Q07020,P61353,P36578,P84098,P39023,P62910,P62081,P47914,P61927,P00390,P62829,P62857,P83881,P15880,P62851,Q96T21,Q02543,P62750,P61254,P62854,P18621,P49207,P08708,P50914,P27635,P61313,P32969,P62263,P26373,P30050,P46779,P18124,P62753,P62266,P83731,P60866,P61247,P62906,Q02878,P46781,P46782,P42766,P62701,P62277,P40429,P62424,P62269,P62241,P62847,P62917,P62913,P46776 53
Cellular response to starvation 0.5947702777738959 0.5479819857831174 0.5837042721997587 1.0 1.0 89 P46777,Q07020,P61353,P36578,P84098,P39023,P62910,P62081,P47914,P61927,P62829,P62857,P83881,P15880,P62851,Q02543,P62750,P61254,Q9Y5K8,P62854,P18621,P49207,P08708,P50914,P27635,P61313,P32969,P62263,Q8N122,Q6IAA8,P26373,P30050,P42345,P46779,P18124,P62249,P62753,P08243,P62266,P83731,P60866,P61247,P62906,Q02878,Q9UI12,P46781,P46782,P42766,P62701,P62277,P40429,P62424,P62269,P62241,P62847,P62917,P62913,P46776 58
Metabolism of polyamines 0.4511171877695505 0.5475201881955183 0.5840214047060586 1.0 1.0 40 O00233,P49721,Q6QHF9,O43242,P28074,P20618,P60900 7
Regulation of tp53 activity through phosphorylation 0.4298778017983173 0.5396243524063277 0.5894561188072027 1.0 1.0 35 Q12962,P19784,O60934,P54646,Q16539,Q96GD4,P15927,Q9UQ84,Q9ULW0,P20248,P35244,P54132,O14965 13
Endogenous sterols 0.8140423031727293 0.5210748912313351 0.6023146014823206 1.0 1.0 2 Q16850 1
Synthesis of pips at the plasma membrane 0.377389477637201 0.5159152938824805 0.6059135718627133 1.0 1.0 12 O00443,Q8TBX8,P61106 3
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3643518963563311 0.5097585060928542 0.6102206589213037 1.0 1.0 21 Q15293,Q07065 2
Srp dependent cotranslational protein targeting to membrane 0.5911738278700638 0.508458277269364 0.6111319920134486 1.0 1.0 92 P46777,Q07020,P61353,P36578,P84098,P39023,P62910,P62081,P47914,P61927,P62829,P62857,P83881,P15880,P60468,P60059,P62851,Q02543,P62750,P61254,P62854,P18621,P49207,P67812,P50914,P08708,P27635,P61313,P32969,P62263,P26373,P30050,P46779,P18124,P62753,P62266,P83731,P60866,P61247,P61619,P62906,Q02878,P46781,P46782,P42766,Q15629,P62701,P62277,P40429,P62424,P62269,P62241,P62847,P62917,P62913,P46776,P09132 57
Prc2 methylates histones and dna 0.4397546785846309 0.4955958787697508 0.620179561057715 1.0 1.0 7 P62805,P84243 2
Base excision repair 0.4030571163314658 0.4921982105981309 0.6225792293176302 1.0 1.0 31 Q9NR33,P62805,P35244,P13051,P41440 5
Activated ntrk2 signals through frs2 and frs3 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr4 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr3 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Frs mediated fgfr3 signaling 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Frs mediated fgfr2 signaling 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr2 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Frs mediated fgfr1 signaling 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Frs mediated fgfr4 signaling 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Stat5 activation downstream of flt3 itd mutants 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr1 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Stat5 activation 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
Signaling by flt3 itd and tkd mutants 0.8011163337250218 0.4860174245275841 0.6269548118756001 1.0 1.0 2 Q06124 1
G alpha s signalling events 0.4358948214105345 0.4804567555349527 0.6309026457437659 1.0 1.0 7 P63096,Q9Y3E5,P32121 3
Fatty acyl coa biosynthesis 0.3399211511262371 0.4798535993525507 0.6313314970745714 1.0 1.0 17 Q6Y1H2,O00767,Q4G176 3
Activation of anterior hox genes in hindbrain development during early embryogenesis 0.3479765063340865 0.4754963658143306 0.6344332229441387 1.0 1.0 19 P52434,O75376,P84243 3
B wich complex positively regulates rrna expression 0.3517760337139002 0.4725538491177632 0.6365315149868458 1.0 1.0 20 P62805,P52434,P84243 3
Cytochrome p450 arranged by substrate type 0.5711976634917971 0.4717643487684297 0.637095000596652 1.0 1.0 3 Q16850 1
Recognition and association of dna glycosylase with site containing an affected purine 0.5709946047344368 0.4711399684603761 0.6375407846799115 1.0 1.0 3 P62805 1
Maturation of sars cov 2 nucleoprotein 0.4830185030507882 0.4627975519337747 0.6435094861476576 1.0 1.0 4 P48729,P49840 2
Homology directed repair 0.4325200376066113 0.4522317402883244 0.6511020445946749 1.0 1.0 41 O60934,P15927,Q9UQ84,Q9NR33,P20248,P62805,P35244,P54132,Q07864,P41440 10
Protein ubiquitination 0.3636097854956573 0.4480105855862509 0.6541455569891812 1.0 1.0 24 Q9GZS3,Q14527,Q9BUN8 3
Met activates ptpn11 0.5599052143595761 0.4375315837384126 0.661725875988243 1.0 1.0 3 Q06124 1
Tight junction interactions 0.78172737955346 0.4353199484095705 0.6633302071810103 1.0 1.0 2 Q9Y624 1
Branched chain amino acid catabolism 0.3424361667846137 0.4332586985639087 0.664826839428325 1.0 1.0 14 P09622,Q99714,Q96RQ3,P26440,P35610,P24752,P45954,O14874 8
Regulation of ras by gaps 0.418348947833527 0.4254138384549666 0.6705350197730806 1.0 1.0 39 O00233,P49721,P60900,O43242,P28074,P20618,P21359 7
Protein methylation 0.4213805218344634 0.4248658255415244 0.6709344885273572 1.0 1.0 7 O60678 1
Signaling by notch3 0.4207672657976337 0.4225663651888439 0.6726116709699859 1.0 1.0 7 P67809 1
Mrna decay by 3 to 5 exoribonuclease 0.3313592733534614 0.4223253381624953 0.6727875660122355 1.0 1.0 15 Q9NQT4,Q969T7 2
Cross presentation of soluble exogenous antigens endosomes 0.4093497359162433 0.4197985857034116 0.6746325981677388 1.0 1.0 37 O00233,P49721,O43242,P28074,P20618,P60900 6
Degradation of axin 0.4093497359162433 0.4197985857034116 0.6746325981677388 1.0 1.0 37 O00233,P49721,O43242,P28074,P20618,P60900 6
Rna polymerase iii transcription initiation from type 3 promoter 0.4189637211818656 0.4158282094206661 0.677535715086415 1.0 1.0 7 P52434 1
Rna polymerase iii chain elongation 0.4189637211818656 0.4158282094206661 0.677535715086415 1.0 1.0 7 P52434 1
Amyloid fiber formation 0.4174434283813441 0.4101769192166474 0.6816761708033809 1.0 1.0 7 P62805,Q93008,P84243 3
Ecm proteoglycans 0.4518351470787153 0.4080422256705836 0.683242674617742 1.0 1.0 5 Q14118 1
Runx1 regulates transcription of genes involved in differentiation of hscs 0.4240499486078922 0.40451237997301 0.6858359760512684 1.0 1.0 42 O00233,P49721,O43242,P28074,P84243,P20618,P62805,P60900 8
Negative regulation of fgfr2 signaling 0.4505143098224837 0.4035777703159167 0.6865232351515889 1.0 1.0 5 Q06124 1
Negative regulation of fgfr4 signaling 0.4505143098224837 0.4035777703159167 0.6865232351515889 1.0 1.0 5 Q06124 1
Negative regulation of fgfr3 signaling 0.4505143098224837 0.4035777703159167 0.6865232351515889 1.0 1.0 5 Q06124 1
Spry regulation of fgf signaling 0.4505143098224837 0.4035777703159167 0.6865232351515889 1.0 1.0 5 Q06124 1
Negative regulation of fgfr1 signaling 0.4505143098224837 0.4035777703159167 0.6865232351515889 1.0 1.0 5 Q06124 1
Signaling by ntrk3 trkc 0.464571425474736 0.4012037525566881 0.6882701181656066 1.0 1.0 4 Q07812 1
Defective cftr causes cystic fibrosis 0.4294050230031125 0.3975173005989345 0.6909860312904412 1.0 1.0 44 O00233,P49721,O43242,P28074,P20618,Q9BUN8,P60900 7
Formation of atp by chemiosmotic coupling 0.358101219057513 0.3969821906637744 0.691380593637763 1.0 1.0 11 P24539 1
Regulation of runx3 expression and activity 0.4047389634122373 0.3874650765844485 0.6984119345179236 1.0 1.0 38 O00233,P49721,O43242,P28074,P20618,P60900 6
Metabolism of vitamins and cofactors 0.4287309079121001 0.381937354455319 0.7025078320430147 1.0 1.0 45 P43490,Q9H2D1,Q5HYK3,Q9HC21,Q96RQ3,Q96EY8,P11498,O75874,Q969G6,P41440,P35270,P05166,Q13057 13
Pyruvate metabolism and citric acid tca cycle 0.385499078284617 0.3725856756436892 0.7094568355981181 1.0 1.0 34 P21912,O75390,P48735,P10515,O43837,P31040,Q02218,P23368,P08559,Q15118,P53985,Q8NCN5 12
Translation of sars cov 2 structural proteins 0.3127721578837705 0.3629564258628511 0.71663743493002 1.0 1.0 17 P39656,Q9H0U3,P48729,Q96SB4,Q10469,Q13724,Q10472,P49840,Q16706,P46977,P04844 11
Phosphorylation of the apc c 0.3338478427821287 0.362619779752248 0.7168889324934078 1.0 1.0 13 P06493,P14635,Q16763,P30260,P53350 5
Regulated necrosis 0.3209673784220152 0.3609509033769464 0.718136149657326 1.0 1.0 19 P41440 1
Abc transporter disorders 0.4228650638931529 0.3609445204651018 0.7181409213037957 1.0 1.0 45 O00233,P49721,O43242,P28074,P20618,Q9BUN8,P60900 7
Asymmetric localization of pcp proteins 0.3970507167899471 0.3592478604515968 0.7194096755750985 1.0 1.0 38 O00233,P49721,O43242,P28074,P20618,P60900 6
Apoptotic cleavage of cellular proteins 0.3290768165127398 0.3591273754754311 0.7194998031206978 1.0 1.0 21 P25054,P55212 2
Rab geranylgeranylation 0.3284702105555656 0.3567871019532346 0.7212511927879561 1.0 1.0 21 P61020,O95716,Q9H0U4,P20340,P51149,Q92696,P61106 7
Degradation of dvl 0.391989505518832 0.3413941184291084 0.7328069022559511 1.0 1.0 38 O00233,P49721,O43242,P28074,P20618,P60900 6
Cdt1 association with the cdc6 orc origin complex 0.4055424589917734 0.337829238129389 0.7354918750885222 1.0 1.0 42 O00233,P49721,O43242,P28074,P20618,Q9Y619,P60900 7
Eukaryotic translation initiation 0.5565802311281798 0.332126720377256 0.7397935742968575 1.0 1.0 100 P55010,Q07020,P61353,P36578,P84098,P39023,P62910,P62081,P47914,P61927,Q13144,P15880,P62851,Q02543,P62750,P61254,P62854,P18621,P49207,P08708,P50914,P27635,P61313,P32969,P62263,P26373,P46779,P18124,P62753,P62266,P83731,P60866,P62906,Q02878,P46781,P42766,P62701,P62277,P40429,P62424,P62269,P62241,P62917,P46776 44
Metabolism of water soluble vitamins and cofactors 0.3768887728837978 0.3281535400399763 0.7427955741221424 1.0 1.0 35 P43490,Q9H2D1,Q9HC21,Q96RQ3,Q96EY8,P11498,Q969G6,P41440,P05166,Q13057 10
Traf3 dependent irf activation pathway 0.5207602350462007 0.3274423068429358 0.7433333722430808 1.0 1.0 3 Q7Z434 1
Traf6 mediated irf7 activation 0.5207602350462007 0.3274423068429358 0.7433333722430808 1.0 1.0 3 Q7Z434 1
Caspase activation via extrinsic apoptotic signalling pathway 0.4253640933745966 0.3222470713879846 0.7472655269704029 1.0 1.0 5 Q13158 1
Regulation of mecp2 expression and activity 0.3223737550799321 0.3180708786882276 0.750431172851382 1.0 1.0 13 Q96GD4,P17612,Q14739,Q13547,O75376 5
Rho gtpases activate wasps and waves 0.3133208894036733 0.3161885787367402 0.7518593762499315 1.0 1.0 20 P63000,Q9UQB8,Q96F07,P62993 4
Rhoq gtpase cycle 0.3273703255599143 0.3071344371592187 0.7587410465699196 1.0 1.0 24 P46940,Q6IAA8,Q07960,O00161,Q9Y6M7,P60953,Q16512,Q86VI3,Q5T2T1,P51149,P27105,Q14155 12
Phospholipid metabolism 0.4231476913349 0.3056203195890637 0.7598937474949672 1.0 1.0 50 Q8TBX8,Q8NAN2,O00443,Q9HCL2,Q8NCC3,Q99943,Q96N66,Q86UL3,Q9NUQ2,P40939,Q9NQZ5,O95674,O14735,Q92604,Q8NCE2,Q32NB8,P61106 17
Myogenesis 0.4048653219400078 0.3013510071158681 0.7631468494371161 1.0 1.0 6 P60953,Q16539 2
Transcriptional regulation of white adipocyte differentiation 0.3093443146401385 0.3006809409874947 0.7636578035199022 1.0 1.0 14 Q71SY5,Q9ULK4,O75376 3
Signal transduction by l1 0.3333285951271706 0.2997741176234757 0.7643494590308764 1.0 1.0 11 P19784,Q16512,P68400,P67870,P63000 5
Bicarbonate transporters 0.7226792009400582 0.2969927598551403 0.7664720366958648 1.0 1.0 2 Q9Y6M7 1
Signaling by notch1 0.3162637792371339 0.2955560017977998 0.7675691786125864 1.0 1.0 13 P32121 1
Signaling by fgfr4 0.4023916786791328 0.293650114112471 0.7690252775585504 1.0 1.0 6 Q06124 1
Signaling by fgfr3 0.4023916786791328 0.293650114112471 0.7690252775585504 1.0 1.0 6 Q06124 1
Signaling by fgfr1 0.4023916786791328 0.293650114112471 0.7690252775585504 1.0 1.0 6 Q06124 1
Transcriptional regulation of granulopoiesis 0.3651058453268777 0.2922043072621078 0.7701304185623039 1.0 1.0 8 P84243 1
Pi metabolism 0.2922685764719911 0.2869583836691283 0.7741441856975906 1.0 1.0 17 O00443,Q8TBX8,P61106 3
Stabilization of p53 0.3825611903296314 0.2868389091896486 0.7742356689587935 1.0 1.0 40 O00233,P49721,O43242,P28074,P20618,P60900 6
Hedgehog on state 0.3979399304914972 0.280331036538073 0.7792235412653243 1.0 1.0 45 O00233,P49721,O43242,P28074,P20618,P32121,Q6PHR2,P60900 8
Rna polymerase iii transcription termination 0.3611867742729701 0.2787802870531849 0.7804134435900183 1.0 1.0 8 P52434 1
Shc1 events in erbb2 signaling 0.712690951821384 0.2762680246571297 0.7823422131699669 1.0 1.0 2 P62993 1
Egfr transactivation by gastrin 0.712690951821384 0.2762680246571297 0.7823422131699669 1.0 1.0 2 P62993 1
Pka mediated phosphorylation of key metabolic factors 0.7126909518213751 0.2762680246571108 0.7823422131699813 1.0 1.0 2 P17612 1
Hdl assembly 0.7126909518213751 0.2762680246571108 0.7823422131699813 1.0 1.0 2 P17612 1
Mastl facilitates mitotic progression 0.4212793944938116 0.2712643701240333 0.7861877079227473 1.0 1.0 4 P14635 1
Recycling of eif2 gdp 0.3947281323877542 0.2703175716952654 0.7869159481351771 1.0 1.0 6 P20042,Q13144,P49770 3
Regulation of runx2 expression and activity 0.3840732509159578 0.2702468291811672 0.7869703679938482 1.0 1.0 42 O00233,P49721,O43242,P28074,P20618,Q13309,P60900 7
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3245049959626259 0.2680994252538966 0.7886227882247252 1.0 1.0 11 Q12834 1
Infectious disease 0.2170947567386385 0.2580123190454268 0.7963973998142426 1.0 1.0 361 Q9H0U3,Q12962,P28074,P12235,Q07020,P61353,P36578,O60942,P84098,P39023,O75376,P62910,P62081,P47914,P61927,P49721,O43242,P15880,P28070,P62851,Q02543,P17612,P62750,P61254,P62854,P46977,P18621,Q9UQB8,P08708,P50914,P27635,P61313,P32969,O00233,P49207,Q9Y3E5,P62263,P26373,P46779,P18124,P62753,P05141,P62805,P62266,P83731,P62906,Q96F07,P51149,P60866,Q02878,Q14241,P46781,P52434,P42766,P12236,P20618,Q16539,Q10469,P62701,P78406,P62277,P40429,P62424,Q92759,P62269,P62241,P61966,P60900,P62917,Q12965,P46776 71
Post translational modification synthesis of gpi anchored proteins 0.4028226992061119 0.2559737326010305 0.7979711201018989 1.0 1.0 5 Q96S52,Q92643,O60762,Q9ULX3 4
Cellular response to hypoxia 0.3739791094323396 0.2517145329823567 0.8012617229286474 1.0 1.0 41 O00233,P49721,O43242,P28074,P20618,P60900 6
Activation of the pre replicative complex 0.309030851442546 0.2485796908280181 0.8036859198377497 1.0 1.0 24 Q9Y619,Q9NR33 2
Dual incision in tc ner 0.3542278152482091 0.2466817392524235 0.8051545398716353 1.0 1.0 36 P41440,Q9NR33,P52434 3
Platelet homeostasis 0.2999505438990094 0.2398546049255355 0.8104429736638599 1.0 1.0 13 Q06124 1
Grb2 sos provides linkage to mapk signaling for integrins 0.4831964221955684 0.2363883053965915 0.8131313700265874 1.0 1.0 3 P62993 1
Syndecan interactions 0.3955796301347758 0.2361534137689182 0.8133136276017279 1.0 1.0 5 O14936,Q9Y296,P17252 3
Rho gtpases activate nadph oxidases 0.3827255266277004 0.2354400809518178 0.8138671801412276 1.0 1.0 6 P63000,Q16539 2
Rna polymerase i transcription termination 0.3065949065185878 0.234593099247981 0.8145245661074361 1.0 1.0 12 P32780,P19447,P17480,Q92759,Q9H9Y6,P52434 6
Rhof gtpase cycle 0.2790008564633757 0.2319052816872734 0.8166115821581805 1.0 1.0 18 P42167,Q9Y6M7 2
Scf skp2 mediated degradation of p27 p21 0.3723998486898043 0.2293676602356843 0.8185831695646537 1.0 1.0 43 O00233,P49721,O43242,P28074,P28070,P20618,Q13309,P60900 8
Tnfr2 non canonical nf kb pathway 0.3688291667984946 0.2290336846813159 0.8188427352955048 1.0 1.0 42 O00233,P49721,O43242,P28074,P20618,P60900,Q8TBC4 7
Trna modification in the nucleus and cytosol 0.2787560394165113 0.2283473795109331 0.8193761938238253 1.0 1.0 15 Q9UBP6 1
Dcc mediated attractive signaling 0.4785113746125556 0.2261505207932886 0.8210843523387059 1.0 1.0 3 P63000 1
Negative regulation of notch4 signaling 0.3637889763902909 0.2250905148373611 0.8219088597244302 1.0 1.0 41 O00233,P49721,O43242,P28074,P20618,P60900 6
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.4771508466571461 0.2232260959773293 0.8233595426637619 1.0 1.0 3 Q00534 1
Regulation of expression of slits and robos 0.5459668294996284 0.2208495333473245 0.8252095936496695 1.0 1.0 125 P28074,Q14118,Q07020,P61353,P36578,P84098,P39023,P62910,P62081,P47914,P61927,P49721,O43242,P15880,P28070,P62851,Q02543,P62750,P61254,P62854,P18621,P49207,P08708,P50914,P27635,P61313,P32969,O00233,P62263,P26373,P46779,P18124,P62753,P62266,P83731,P60866,P62906,Q02878,P46781,P42766,P20618,P62701,P62277,P40429,P62424,P62269,P62241,P60900,P62917,P46776 50
Transcriptional regulation by runx2 0.3914101984210197 0.2192016521641459 0.8264929685388092 1.0 1.0 50 O00233,P14635,P49721,O43242,P28074,P20618,Q13309,Q07812,P60900 9
Oxidative stress induced senescence 0.2733497935732627 0.2160811802611908 0.8289244691668531 1.0 1.0 18 P62805,P84243,Q16539 3
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.3929837801088662 0.2154514130544177 0.8294153892358389 1.0 1.0 51 O15371,P62081,O75822,P62857,P15880,P62851,P62854,P08708,P62263,P62249,P62753,P62266,P60866,P61247,P62861,P46781,Q15056,P46782,P62701,P20042,P62277,P62269,P62241,P62847,P62280 25
Auf1 hnrnp d0 binds and destabilizes mrna 0.3624699547906181 0.2135436420614912 0.830902952590902 1.0 1.0 42 O00233,P49721,O43242,P28074,P20618,P60900 6
Signalling to erks 0.2991451484302921 0.2112717008164155 0.8326752639948873 1.0 1.0 12 P11233,P11234,Q16539 3
Uch proteinases 0.3808011211907931 0.2096280836194812 0.8339579590575645 1.0 1.0 48 O00233,P49721,O43242,P28074,P20618,P60900,Q8NB78 7
Response of eif2ak1 hri to heme deficiency 0.4702768748818886 0.2087886513337202 0.8346132310216692 1.0 1.0 3 P08243 1
Retrograde transport at the trans golgi network 0.2898506115182111 0.2069735703322137 0.8360304993883889 1.0 1.0 23 P83436,O43752,P53365,Q96JB2,O60499,P20340,Q5VZE5,P40616 8
G1 s dna damage checkpoints 0.358323011803591 0.2039834140770684 0.8383664600632794 1.0 1.0 42 O00233,P49721,O43242,P28074,P28070,P20618,P60900 7
Abc family proteins mediated transport 0.3965187926011421 0.2025331745903358 0.8394999261849758 1.0 1.0 54 O00233,P49721,O43242,P28074,P20618,O15439,Q9BUN8,P60900,P08183 9
Cyclin a cdk2 associated events at s phase entry 0.3644212281192934 0.2025033395050253 0.839523247946262 1.0 1.0 44 O00233,P49721,O43242,P28074,P28070,P20618,Q13309,P60900 8
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3902510385143921 0.2023594493463444 0.839635727294477 1.0 1.0 52 O00233,P49721,O43242,P28074,Q12834,P28070,P20618,Q16763,Q13309,P60900,P53350 11
Pre notch expression and processing 0.295864690728581 0.2014436484075376 0.8403516881693671 1.0 1.0 12 P20340,P84243 2
Transcriptional regulation by mecp2 0.2621828407489239 0.1974759605629499 0.8434550917201913 1.0 1.0 17 P17612,Q8WYQ5,Q14739,Q13547,O75376 5
Developmental biology 0.3056492613081281 0.1965026056282849 0.8442167934284595 1.0 1.0 272 P28074,O75448,Q14118,Q07020,P61353,P36578,P84098,P39023,O75376,P62910,P62081,P47914,P61927,Q14155,P49721,O43242,P15880,P28070,P62851,Q02543,P17612,P62750,P61254,P62854,P18621,P49207,P08708,P50914,P27635,P61313,P32969,O00233,P62263,Q71SY5,Q9ULK4,P26373,P84243,P46779,P18124,P62753,P62805,P62266,P83731,P60866,P61247,P62906,Q02878,P46781,P52434,Q06124,P60900,P42766,P07942,P20618,Q16539,Q16850,P62701,P62277,P07737,P62424,P40429,P62269,Q13740,P62241,P62847,P62917,P46776 67
G2 phase 0.6642185663924733 0.1878811177063359 0.85096984502677 1.0 1.0 2 P20248 1
Adora2b mediated anti inflammatory cytokines production 0.3070385125354146 0.1864863402647518 0.852063389857106 1.0 1.0 10 P63096,Q9Y3E5,P08754,P17612 4
Activation of atr in response to replication stress 0.2691559708228922 0.1854278168791314 0.8528934920093818 1.0 1.0 20 Q9Y619 1
Dectin 1 mediated noncanonical nf kb signaling 0.3501225391455193 0.1795999790041302 0.8574666211657638 1.0 1.0 43 O00233,P49721,O43242,P28074,P20618,P60900,Q8TBC4 7
Cell cell junction organization 0.3042690149582318 0.1783514674076591 0.8584469615358097 1.0 1.0 10 P15151 1
G alpha 12 13 signalling events 0.3105946634305306 0.1741130294190786 0.8617766336064103 1.0 1.0 9 O75116,Q14155 2
P75 ntr receptor mediated signalling 0.2529146735420461 0.1669206777035757 0.8674324629506796 1.0 1.0 18 Q9NQC3,Q13547,P63000,Q14344,Q14155 5
Translation 0.4553531582971301 0.1633741065909233 0.8702238889048499 1.0 1.0 219 P55010,P61353,Q9NSE4,Q9P0M9,P15880,P60059,P62851,P82663,P49207,P62263,P82675,P09001,P60866,P61247,P61619,Q02878,Q9BRJ2,Q15629,P62424,Q9BYD2,P62847,P62917,Q9Y2Q9,P82912,Q07020,P49406,P36578,Q6P1L8,Q9Y2R5,P62910,Q9BW92,P47914,P60468,Q02543,P82914,Q92552,P62854,P67812,P50914,Q8N983,P26640,P18124,P46779,P62753,Q9NP81,P62266,P83731,P46781,P26641,Q9NX20,P46782,O75616,Q6PI48,P62277,Q9NYK5,P62241,P82930,P62913,P46777,P51398,P84098,Q15070,P39023,Q9BYD1,Q13144,P62857,P62829,P83881,Q9BZE1,Q7Z2W9,Q9Y399,P18621,P08708,P27635,P26373,P30050,P62249,P62906,Q9Y3D3,P42766,Q9Y2Z4,P40429,Q9P015,P46776,P09132,P62081,P61927,Q9NP92,P62750,P61254,P61313,P32969,Q96DV4,Q14197,P62701,Q9HD33,P62269,O15235 98
Signaling by notch4 0.3444111957330188 0.1629287706298519 0.870574517808413 1.0 1.0 44 O00233,P49721,O43242,P28074,P20618,P60900 6
Rrna modification in the nucleus and cytosol 0.3741473314812079 0.1603482417831166 0.8726067590238991 1.0 1.0 54 Q9NX24,Q14692,Q9Y2X3,P62081,Q9UNQ2,Q9BVI4,O15213,P15880,Q9Y2R4,Q9Y6V7,O43818,P62263,P62753,P78316,P46781,O75691,P55769,Q9NXG2,Q9NQZ2,Q8IY37,Q13601 21
Degradation of gli1 by the proteasome 0.339115010070138 0.1594480474685427 0.8733158866728987 1.0 1.0 43 O00233,P49721,O43242,P28074,P20618,P17612,P60900 7
Transcriptional regulation by runx3 0.3421708546343135 0.1590884193089559 0.8735992120740916 1.0 1.0 44 O00233,P49721,O43242,P28074,P20618,P60900 6
Regulation of pten stability and activity 0.3387263383150595 0.15878857498981 0.8738354504409966 1.0 1.0 43 O00233,P49721,O43242,P28074,P20618,P60900 6
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.3372886024970969 0.1581974721486712 0.8743011956059628 1.0 1.0 7 P15151 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.3635755982611637 0.1530893322341369 0.878327828357651 1.0 1.0 52 O00233,P14635,P49721,O43242,P28074,P20618,O95067,P60900,Q9NYZ3,P53350 10
Rhob gtpase cycle 0.2639342525072933 0.1511363492993745 0.8798681592335729 1.0 1.0 23 P41440,O00161,O60245 3
Signaling by robo receptors 0.5121863412347775 0.1465733639184197 0.8834687790900397 1.0 1.0 141 P28074,P60953,Q14118,Q07020,P46777,P61353,P36578,P84098,P39023,P62910,P62081,P47914,P61927,P49721,P62829,P62857,O43242,P83881,P15880,P28070,P62851,Q02543,P17612,P62750,P61254,P62854,P18621,P49207,P08708,P50914,P27635,P61313,O75832,O00233,P62263,P32969,P26373,P30050,P46779,P18124,P62753,P62266,P83731,P60866,P61247,P62906,Q02878,P46781,P46782,P60900,P42766,P20618,P62701,P62277,P07737,P62424,P40429,Q9HAU5,P62269,P63000,P62241,P62847,P62917,P62913,P46776 65
Cell death signalling via nrage nrif and nade 0.2843090206781847 0.1465183250574637 0.8835122247214411 1.0 1.0 11 P63000,Q14344,Q14155 3
Pcp ce pathway 0.355767362104441 0.1459144995692136 0.883988885099837 1.0 1.0 51 O00233,P49721,P20618,P32121,P07737 5
Rhoc gtpase cycle 0.2927572139612705 0.1446969567445097 0.884950142037576 1.0 1.0 32 P41440 1
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.4348600500621177 0.1435730987973209 0.8858375845847435 1.0 1.0 3 Q96T60 1
The citric acid tca cycle and respiratory electron transport 0.4564624609404567 0.1434585348491918 0.8859280568568337 1.0 1.0 93 P31930,P48735,Q9Y6M9,O75880,O95182,P53985,O95168,O43674,Q9NPL8,P24539,O75306,O95139,O96000,O75380,O00483,P03886,Q9BSH4,O75964,Q16795 19
Anti inflammatory response favouring leishmania parasite infection 0.2317804276224507 0.1412884437069344 0.887642078620354 1.0 1.0 16 P17612,Q16539 2
Hedgehog ligand biogenesis 0.3257625147867584 0.1387576269997418 0.8896416787398385 1.0 1.0 43 O00233,P49721,O43242,P28074,P20618,P60900 6
G1 s specific transcription 0.2891150948817642 0.1370878175553632 0.8909613817374644 1.0 1.0 10 P06493,P09884,Q9Y619,Q13547 4
Rac1 gtpase cycle 0.3227269905523766 0.1346027717240329 0.8929259500351006 1.0 1.0 43 P50402,Q6IAA8,P46940,O00161,P60953,P42167,Q86VI3,Q86UP2,Q5T2T1,P51149,Q14739,Q96F07,P63000,Q9UQB8,Q14344,Q14155 16
Metabolism of rna 0.1789195448450344 0.1339382863335203 0.893451374916943 1.0 1.0 476 P28074,P61353,Q9NPI6,P49721,O15213,O43242,O95628,P15880,P28070,P62851,Q9Y6V7,P49207,P08621,O43818,P62263,Q96GA3,Q969T7,P60866,P61247,Q02878,Q99547,Q96F86,P52434,Q6PGP7,Q53GS9,Q9UBP6,P20618,P62424,P62917,Q9H9L3,Q07020,P36578,O60942,P62910,P47914,Q02543,Q9Y606,P62854,P50914,O00233,Q9NQT4,P46779,P18124,P62753,P62266,P83731,Q9UKZ1,P62314,P46781,Q16539,P62277,Q969Y2,P62241,P60900,Q9GZS3,P84098,P39023,Q9BVI4,Q9NXF1,Q99575,P18621,P08708,P27635,P26373,P62906,P42766,P40429,P67809,P46776,Q5TAX3,P62081,P61927,Q96BP3,Q9UNQ2,P62750,P61254,P61313,P32969,P55769,P62701,Q9NXG2,P62269,O00541,P78406,Q92759 85
Parasite infection 0.2631520601035348 0.1320830129520843 0.8949186318866857 1.0 1.0 26 P62993,Q96F07,P63000,Q9UQB8,Q12965 5
Processive synthesis on the lagging strand 0.2492244130481964 0.1319439446708666 0.895028629636744 1.0 1.0 14 P15927,P09884,P49642,P35244 4
Formation of the beta catenin tcf transactivating complex 0.26778822343268 0.1287604447007215 0.8975472054694578 1.0 1.0 12 P84243 1
Metabolism of nucleotides 0.3314732827655137 0.1260722779651756 0.8996747113316799 1.0 1.0 48 Q9H773 1
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.2562726801609499 0.1251979911997056 0.9003668075233586 1.0 1.0 13 Q12834 1
Apc cdc20 mediated degradation of nek2a 0.2562726801609499 0.1251979911997056 0.9003668075233586 1.0 1.0 13 Q12834 1
Dna damage reversal 0.3367944370964398 0.1227266136260344 0.9023235885462524 1.0 1.0 6 Q8N9N2 1
Cdc42 gtpase cycle 0.2800038699608256 0.1221187991195581 0.9028049337635036 1.0 1.0 33 P46940,Q6IAA8,O00161,P60953,P42167,Q86VI3,Q86UP2,P51149,Q14739,Q9UQB8,Q14344,Q14155 12
Negative epigenetic regulation of rrna expression 0.2586216099505339 0.1212053417071017 0.9035283932427663 1.0 1.0 27 P62805,P26358,P52434,P84243 4
Metabolism of amino acids and derivatives 0.4710549946552985 0.120779210404956 0.9038659172344464 1.0 1.0 187 P28074,P61353,Q96C36,P49721,O43242,P15880,P28070,P62851,P49207,P45954,P62263,Q6QHF9,Q9Y619,P60866,P61247,Q02878,P20618,P62424,Q9UBX3,P62847,P62917,P34896,Q07020,P36578,P62910,P47914,Q9UJS0,Q02543,P35610,Q9BV20,P62854,P50914,O00233,Q02218,P46779,P18124,P62753,P62266,P83731,P46781,P46782,P62277,P62241,P60900,P62913,O14874,O75746,P46777,P08559,P84098,P39023,P62829,P62857,P83881,Q96T21,P18621,P08708,P27635,O75832,P10515,P26373,P30050,Q96RQ3,P62906,P42766,P40429,P46776,P32322,P62081,P61927,P00390,P62750,P61254,P61313,P32969,P00367,P08243,P62701,P62269 79
Rna polymerase ii transcription 0.173464121073383 0.1201486811135061 0.9043653697160988 1.0 1.0 330 Q12962,P28074,Q9GZS3,Q9UQ84,O75880,Q9HCL2,O75448,O43819,O60942,Q96GM5,O75376,Q92696,Q9Y2F5,P00390,P49721,P14635,Q8TBX8,O43242,O95628,P28070,P55212,P17612,Q16763,P35244,Q07812,Q96SY0,Q00534,O00233,Q8N122,Q9NV88,Q6IAA8,Q71SY5,Q9ULK4,P84243,P62805,O00483,Q9UKZ1,Q14241,P52434,Q06124,Q9BSH4,P54646,P20618,Q16539,Q13309,P54132,P60900,Q92759 48
G2 m dna damage checkpoint 0.2765198073761835 0.1180431229993402 0.9060334895057088 1.0 1.0 33 P14635,O60934,Q9UQ84,P62805,P35244,P54132 6
Apc c mediated degradation of cell cycle proteins 0.3578868746164171 0.117741071596745 0.9062728226715288 1.0 1.0 60 O00233,P14635,P49721,O43242,P28074,Q12834,P28070,P20618,Q16763,Q13309,O14965,P60900,P53350 13
Diseases of mitotic cell cycle 0.2144542772861461 0.1153905078147518 0.908135602372879 1.0 1.0 16 Q9UJX4,Q13042,Q9UJX3,P46100,Q9UJX6,P11802,Q16763,Q9UM13,Q13309,Q9UJX2,Q00534,P30260,Q96DE5,P24941,Q9UER7 15
Signaling by braf and raf1 fusions 0.2455003012113845 0.1139305047358514 0.9092928837202908 1.0 1.0 25 P32121,P51797 2
Signaling by csf3 g csf 0.3028671494295941 0.1129598599123328 0.9100623786168154 1.0 1.0 8 Q06124 1
Antigen processing cross presentation 0.3316994008886166 0.1114252241332386 0.9112791586379468 1.0 1.0 53 O00233,P49721,O43242,P28074,O00161,P28070,P60059,P20618,Q9UIQ6,O75396,P60900 11
Regulation of pyruvate dehydrogenase pdh complex 0.3013178568114874 0.109497494863853 0.9128079086322908 1.0 1.0 8 P10515,Q15118,Q8NCN5,P08559 4
The role of nef in hiv 1 replication and disease pathogenesis 0.23658286277089 0.1093334636543739 0.9129380055227558 1.0 1.0 14 O43747,Q96CW1,P61966,Q9UI12,P63000,P56377 6
Metabolism of steroids 0.3173905560291858 0.1089687120823036 0.9132273066647096 1.0 1.0 49 O00767,O75845,Q16850,Q9HCL2,O95772,P48449 6
Degradation of beta catenin by the destruction complex 0.321767069903382 0.107819514739258 0.914138862607044 1.0 1.0 51 P25054,P49721,O00233,O43242,P28074,P20618,P60900 7
Mapk6 mapk4 signaling 0.3187405403779841 0.1076826606122015 0.9142474243521777 1.0 1.0 50 O00233,P49721,O43242,P28074,P28070,P60953,P20618,P17612,P60900,P63000,O75832 11
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.2674537171951395 0.1074919087611678 0.914398744005394 1.0 1.0 11 P84243 1
Orc1 removal from chromatin 0.3258148339638142 0.1065503258445803 0.915145728377384 1.0 1.0 53 O00233,P49721,O43242,P28074,P20618,Q9Y619,Q13309,P60900 8
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.2846245370252478 0.1055735286495174 0.9159207284267694 1.0 1.0 9 Q9UKZ1,O95628 2
Rrna processing 0.4591663670149527 0.1051440719440951 0.9162614887396718 1.0 1.0 167 Q9BVS4,Q9H9L3,P46777,Q07020,P61353,P36578,P84098,Q9Y2X3,P39023,P62910,P62081,P47914,P61927,P62829,O15213,Q9BVI4,P62857,P15880,P83881,Q9UNQ2,P62851,Q02543,Q8IY81,P62750,Q9NXF1,P61254,Q9Y2R4,Q9Y6V7,P62854,P18621,P49207,P08708,P50914,P27635,P61313,P32969,O43818,P62263,Q9NQT4,P26373,Q96GA3,P30050,P46779,P18124,P62249,P62753,P62266,Q9NQT5,P83731,P60866,P61247,P62906,Q02878,Q99547,P46781,P46782,P42766,O75691,P55769,P62701,Q9NXG2,P62277,P40429,P62424,P78345,Q7L0Y3,P46776,P62269,P62241,O00541,P62847,P62917,Q8IY37,P62913,Q13601 75
Nervous system development 0.3469581371806668 0.1003743442686377 0.9200471371933154 1.0 1.0 224 P28074,P61353,P49721,O43242,P15880,P28070,P62851,P49207,P62263,P60866,P61247,Q02878,P07942,P20618,Q16850,P07737,P62424,P62847,P62917,O75116,Q14118,Q07020,P36578,P62910,P47914,P62993,Q02543,P62854,P50914,O00233,P04035,P19784,P46779,P18124,P62753,P62266,P83731,P46781,Q06124,P46782,Q16539,P62277,Q9NR12,Q13740,P62241,P60900,Q9HAU5,P63000,P62913,P60953,P46777,P84098,P39023,Q9Y490,Q14155,P62829,P62857,P83881,P17612,P18621,P08708,P27635,O75832,P26373,P30050,P62906,P42766,P40429,P46776,P62081,P61927,P62750,P61254,P61313,P32969,P62701,P62269 77
Fatty acid metabolism 0.3295809693790813 0.0982387588117736 0.9217427062164694 1.0 1.0 59 P23786,O00767,Q96CM8,Q9UJ83,O43772,Q16836,P53007,Q6Y1H2,O43808,Q15067,O95864,P09960,P11310,P51648,Q4G176 15
Translocation of slc2a4 glut4 to the plasma membrane 0.2791845307487505 0.0978854812048608 0.9220232289371229 1.0 1.0 41 O00161,Q9NV70,P54646,Q9UIQ6,Q12965,P11233,Q8TAG9,P61106 8
Tp53 regulates metabolic genes 0.2755779718731364 0.0974742933746243 0.9223497479169384 1.0 1.0 40 Q6IAA8,Q8N122,Q9BSH4,P54646,O75880,O43819,O00483,P00390 8
Death receptor signalling 0.2310815178968057 0.0972087707431374 0.9225606029890754 1.0 1.0 26 Q9NQC3,Q13547,Q13158,O95429,Q14344,Q14155 6
Apoptotic execution phase 0.2492466200986703 0.0963307740804816 0.92325787055104 1.0 1.0 32 P25054,P55212,P51572 3
Hdr through mmej alt nhej 0.3092085907619967 0.0958690537362579 0.9236245728829008 1.0 1.0 7 P49916,O60934,P18887,Q92878,P09874,P39748 6
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.4006817937700944 0.095381259767434 0.9240120007468452 1.0 1.0 3 P63000 1
Hdacs deacetylate histones 0.1975871436809823 0.0947054215499637 0.9245488115627593 1.0 1.0 17 P62805,Q13547,O75376 3
Influenza infection 0.4203186900273336 0.0930210090469704 0.9258868707799012 1.0 1.0 128 Q07020,P61353,P36578,P84098,P39023,P62910,P62081,P47914,P61927,P15880,P62851,Q02543,P62750,P61254,P62854,P18621,P49207,P08708,P50914,P27635,P61313,P32969,P62263,P26373,P46779,P18124,P62753,P62266,P83731,P60866,P61247,P62906,Q02878,P46781,P52434,P42766,P12236,P62701,P62277,P40429,P62424,Q9BTX1,P62269,P62241,P78406,P62917,P46776 47
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.2105060833618205 0.0928346403228096 0.926034930832898 1.0 1.0 15 P62805,Q13547,P84243 3
Transport of small molecules 0.2331937706952728 0.0909118995843165 0.9275625948491156 1.0 1.0 161 O00233,P49721,Q9H0U3,Q9Y6M7,P20618,Q8WTV0,Q8N4V1,Q9UHQ9,Q9Y277,O00400,Q9BUN8,Q9UBX3,P35610,P60900,P53985,P08183,P51797 17
Regulation of hmox1 expression and activity 0.283839404872884 0.0908262789122562 0.9276306287961285 1.0 1.0 47 O00233,P49721,O43242,P28074,P20618,Q13309,P60900 7
Beta catenin independent wnt signaling 0.3084901791706447 0.0903132082060609 0.9280383244141686 1.0 1.0 57 O00233,P49721,P20618,P32121,P07737 5
Fceri mediated nf kb activation 0.2792977585049854 0.0899793320277246 0.9283036388488164 1.0 1.0 46 O00233,P49721,O43242,P28074,P20618,P60900 6
Cell cycle checkpoints 0.2214397903900542 0.0899724172841082 0.9283091337285788 1.0 1.0 154 P28074,Q9UQ84,P49454,P20248,Q9H900,P53350,Q16537,P49721,P14635,O43242,P28070,Q16763,O43683,P35244,Q9NYZ3,O00233,Q9Y619,Q71F23,P62805,O95067,Q96IY1,O60934,Q12834,P20618,P15927,P54132,P60900,Q8WYP5 28
Signaling by notch 0.3256207030328583 0.0897349525795194 0.9284978398332122 1.0 1.0 65 O00233,P49721,O43242,P28074,P84243,P20618,P32121,P67809,P62805,P20340,O75376,P60900 12
Interleukin 1 family signaling 0.2945208015216892 0.0897106713896716 0.9285171355959798 1.0 1.0 52 O00233,P49721,O43242,P28074,P20618,P60900,Q06124 7
Dna replication pre initiation 0.3270273273066468 0.088732211948788 0.9292947320637306 1.0 1.0 67 O00233,P49721,O43242,P28074,P28070,P84243,P20618,Q9Y619,Q9NR33,P62805,P35244,Q07864,P60900 13
Telomere maintenance 0.2699164214037883 0.0882457148270601 0.9296813838359526 1.0 1.0 44 P84243,P62805,P35244,P41440,P52434 5
Clec7a dectin 1 signaling 0.2831734746600522 0.0882354662362504 0.9296895292547672 1.0 1.0 49 O00233,P49721,O43242,P28074,P20618,P60900,Q8TBC4 7
Transcriptional regulation by tp53 0.2448603012768993 0.0876913800994016 0.9301219709148648 1.0 1.0 137 Q12962,O94776,Q9UQ84,O75880,O43819,P20248,Q92696,P00390,P14635,Q8TBX8,O95628,Q96GD4,P55212,P35244,Q07812,P49815,P06493,Q8N122,Q6IAA8,P19784,P42345,P42704,O00483,Q9UKZ1,Q13547,P10606,Q9NVI1,Q14241,P15954,P52434,Q9BSH4,O60934,P54646,Q16539,P15927,Q9ULW0,P68400,P54132,O14965,Q92759,A5YKK6 41
Rhoa gtpase cycle 0.2802496228174684 0.0871178170515233 0.9305778632696712 1.0 1.0 49 O00161,P42167,P51572,Q96HY6,P41440,Q14155 6
Notch hlh transcription pathway 0.3181113639200789 0.0870101561527233 0.9306634392841842 1.0 1.0 6 O75376 1
Factors involved in megakaryocyte development and platelet production 0.2838393764356032 0.0866032824176147 0.9309868567140612 1.0 1.0 51 O95140,Q96Q89,O00139,P47755,Q92667,P84243,P60953,P17612,Q8IWA4,P17252,Q13547,P27144,Q86Y91,Q9UIJ7,P63000,O95235,O95239 17
Tcf dependent signaling in response to wnt 0.3139144043259018 0.0860893498995813 0.9313953897417792 1.0 1.0 65 P25054,P49721,O00233,P19784,O43242,P28074,P28070,P84243,P20618,P40818,P62805,Q13547,P60900,Q16537 14
Interleukin 1 signaling 0.2763312172760028 0.0857482689862034 0.9316665303005328 1.0 1.0 49 O00233,P49721,O43242,P28074,P20618,P60900 6
Apoptotic cleavage of cell adhesion proteins 0.3170588235294074 0.0851770145150054 0.932120663920347 1.0 1.0 6 Q14126,P42574,Q07157,P35222,P15924 5
Class i mhc mediated antigen processing presentation 0.2819418981508805 0.0851596676174761 0.9321344546347704 1.0 1.0 118 P28074,P19474,P49721,O43242,P28070,P60059,Q16763,Q9UIQ6,P51572,Q9UII4,O95486,P55786,O00233,O00161,O75396,P61619,Q12834,P20618,Q5T4S7,Q15386,Q13309,P60900,Q8TBC4,Q92990 24
Ub specific processing proteases 0.3296897090096953 0.0851094258163632 0.9321743967814208 1.0 1.0 76 O00233,P49721,Q12962,Q8IXI2,O43242,P28074,Q9Y3E5,Q12834,P20618,P40818,P32121,Q9Y277,Q13309,Q96RU2,P60900 15
Dna double strand break repair 0.2884820032434348 0.0850649332573664 0.9322097684329425 1.0 1.0 55 O60934,P15927,Q9UQ84,Q9NR33,P20248,P62805,P35244,P54132,Q07864,P41440 10
Separation of sister chromatids 0.1816118590032595 0.0848737762316826 0.9323617400790238 1.0 1.0 116 O00233,P49721,O43242,P28074,Q12834,P20618,Q7Z5K2,Q71F23,P49454,Q16763,O43683,Q9H900,Q96IY1,P60900,P53350,Q8WYP5 16
Transcription coupled nucleotide excision repair tc ner 0.2683700112064647 0.0847915226478224 0.932427133216365 1.0 1.0 47 P41440,Q9NR33,P52434 3
Dna repair 0.2041394260555607 0.0846055327705474 0.9325750003277852 1.0 1.0 114 Q9UQ84,Q7L5N1,P20248,Q8N9N2,P41440,Q9UNS1,Q15004,Q16658,Q92890,P35244,Q07864,P13051,Q9NR33,P62805,Q8N3C0,P52434,O60934,P15927,Q15554,P54132,Q92759 21
Oncogenic mapk signaling 0.2267570962885405 0.084361869965359 0.9327687225367952 1.0 1.0 32 P46940,P32121,P30086,Q99956,Q6RW13,P21359,O00203,P51797 8
Cytoprotection by hmox1 0.3126116037643598 0.0840614513996383 0.933007573449968 1.0 1.0 69 P28074,O75880,O43819,O75376,P49721,O43242,P28070,O75832,O00233,P19784,P42704,O00483,P10606,P15954,Q9BSH4,Q13618,P20618,P68400,Q13309,P60900 20
Regulation of tp53 activity 0.2910087420478082 0.0839933771986261 0.9330616973923368 1.0 1.0 58 P06493,Q12962,O94776,Q8TBX8,P19784,P42345,O60934,Q96GD4,P54646,Q9UQ84,Q16539,P15927,Q9ULW0,P20248,P35244,P54132,Q13547,O14965 18
Intra golgi and retrograde golgi to er traffic 0.2374198493580287 0.0838025470105645 0.9332134229241272 1.0 1.0 108 Q96Q89,P53365,Q9P2W9,Q9NZ32,Q9H0U4,Q8TBA6,Q5VZE5,Q8N6T3,O00461,P83436,A2RRP1,Q12981,P84085,P20340,P40616,P24390,Q96JB2,Q13190,O60499,Q9UID3,O75396,Q9BVK6,P62820,Q86Y91,O43752,P47755,Q9UJW0,O15260,O95249,O95235 30
Programmed cell death 0.2232503697845198 0.0835331406735314 0.9334276270194042 1.0 1.0 106 P25054,P49721,O00233,P20618,P55212,P51572,Q07812,P60900,P41440 9
Antigen processing ubiquitination proteasome degradation 0.3312992582397526 0.0834203414544142 0.9335173147412954 1.0 1.0 94 P55786,P49721,O00233,O43242,P28074,Q12834,P20618,Q5T4S7,Q15386,Q16763,Q9UIQ6,Q13309,P19474,P60900,Q9UII4,Q8TBC4,Q92990 17
Deubiquitination 0.3225451969015682 0.083150124293283 0.9337321703823236 1.0 1.0 97 P25054,P49721,O00233,O95630,O43242,P28074,Q12834,P20618,Q8IXI2,Q12962,Q9Y3E5,Q9Y277,P32121,P40818,Q13309,Q96RU2,P60900,Q8NB78 18
S phase 0.2162523387277378 0.0828625234303432 0.933960853492156 1.0 1.0 101 O00233,P49721,Q7Z5K2,P20618,Q9Y619,Q9NR33,P35244,P41440 8
C type lectin receptors clrs 0.276924548871029 0.0827152753501417 0.9340779385230124 1.0 1.0 54 O00233,P49721,O43242,P28074,P20618,P17612,P60900,Q8TBC4 8
Dna replication 0.2217410737680132 0.0824611523676464 0.934280009007782 1.0 1.0 98 O00233,P49721,P20618,P84243,Q9Y619,Q9NR33,P35244,P41440 8
Intracellular signaling by second messengers 0.1950118510495533 0.082057310543347 0.93460113984328 1.0 1.0 95 O94776,P28074,Q16537,P49721,O43242,Q8TBX8,P62993,P28070,P17612,P49815,O75832,O00233,Q8N122,Q6IAA8,P19784,P42345,Q13547,Q06124,P20618,P49840,P60900,P63000 22
Rna polymerase i transcription 0.2087966935284623 0.0819737026638992 0.93466762529435 1.0 1.0 28 O94776,P84243,P32780,P62805,Q13547,Q92759,P52434 7
G2 m checkpoints 0.3061995324948259 0.081837587380356 0.9347758658999716 1.0 1.0 86 O00233,P49721,P14635,O60934,O43242,P28074,P28070,P20618,Q9UQ84,Q9Y619,P62805,O95067,P35244,P54132,P60900,Q9NYZ3 16
Disorders of transmembrane transporters 0.30753852877712 0.0818276866458447 0.9347837391371128 1.0 1.0 79 O00233,P49721,P20618,O00400,Q9BUN8,P53985 6
Apoptosis 0.2187990286955663 0.0817914429314295 0.934812560826738 1.0 1.0 93 P25054,P49721,O00233,P20618,P55212,P51572,Q07812,P60900 8
Signaling by wnt 0.2627937991274724 0.0817153069456004 0.9348731058859748 1.0 1.0 92 P25054,P49721,O00233,P20618,P84243,P40818,P32121,P07737,P60900,Q9Y3A6 10
Transcriptional regulation by runx1 0.2994374875386426 0.0816727097940725 0.9349069802693905 1.0 1.0 71 O00233,P49721,P84243,P20618,Q9HCL2,Q96GM5,Q06124 7
Synthesis of dna 0.2229896817492162 0.0816588361104685 0.934918013015591 1.0 1.0 92 O00233,P49721,P20618,Q9Y619,Q9NR33,P35244,P41440 7
Positive epigenetic regulation of rrna expression 0.218607797733158 0.0815432673069768 0.935009917087352 1.0 1.0 32 P62805,P52434,P84243 3
Switching of origins to a post replicative state 0.2863327183360449 0.0813865458819501 0.9351345484457532 1.0 1.0 63 O00233,P49721,O43242,P28074,P20618,Q9Y619,Q16763,Q13309,P60900 9
Cellular response to chemical stress 0.2971562612878253 0.0811408092766169 0.9353299715560784 1.0 1.0 78 O00233,P49721,Q9BSH4,O43242,P28074,P20618,O75880,O43819,Q13309,O00483,O75376,P60900,P00390 13
Rab gefs exchange gtp for gdp on rabs 0.2062679890252979 0.0811367608319698 0.9353331911320522 1.0 1.0 28 P61020,P20340,P61106,Q9H0U4 4
Signaling by vegf 0.2163361905545032 0.0808736079102447 0.9355424690331724 1.0 1.0 32 Q9UQB8,Q96F07,Q16539 3
Mitotic g1 phase and g1 s transition 0.2776898300124368 0.0806937104217476 0.9356855388622828 1.0 1.0 82 P28074,P20248,P49721,P14635,O43242,P28070,P35244,Q07864,Q00534,O75832,O00233,P06493,P09884,Q9Y619,Q9NR33,Q13547,P49642,P20618,P15927,Q13309,P60900 21
Biological oxidations 0.2423705545354884 0.0800805484826824 0.9361731931179198 1.0 1.0 44 Q6QHF9,Q9NUJ1,Q16850 3
Golgi to er retrograde transport 0.2363696506394074 0.0799644529890064 0.9362655278088176 1.0 1.0 79 Q12981,Q9P2W9,Q9NZ32,Q9H0U4,P20340,O75396,O15260,Q86Y91,P24390 9
Neddylation 0.190267555081641 0.0795120420107055 0.93662535379957 1.0 1.0 76 O00233,P49721,O43242,P28074,P20618,Q7L5N1,Q92564,Q13309,P60900,Q8TBC4,Q5TAQ9 11
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.2415368287032476 0.0794757160215812 0.9366542463111838 1.0 1.0 12 O43747,Q96CW1,P61966,Q9UI12,P56377 5
Copi dependent golgi to er retrograde traffic 0.2587672733389698 0.0794514424373389 0.9366735527779996 1.0 1.0 55 Q12981,Q9P2W9,Q9H0U4,O15260,Q86Y91,P24390 6
Signaling by hedgehog 0.266991426105685 0.0793691952930687 0.9367389699188492 1.0 1.0 65 O00233,P49721,P20618,P32121,Q6PHR2,P60900 6
Runx3 regulates p14 arf 0.5740305522914162 0.0789284962356921 0.9370894972224146 1.0 1.0 2 P25440 1
Extension of telomeres 0.2079338423431844 0.0787797546791323 0.937207807416658 1.0 1.0 32 P09884,P49642,P15927,Q15554,P20248,P35244,P54132,P41440 8
Pten regulation 0.2139633051246463 0.078745225309815 0.9372352725447016 1.0 1.0 70 O00233,P49721,Q8N122,Q6IAA8,O43242,P28074,P20618,P60900 8
Mitochondrial protein import 0.2170402141724361 0.0786901243363496 0.9372791007599752 1.0 1.0 36 O75390,P12236,Q5JRX3,O75746,P62072,P12235,Q9Y5J7,O43615,Q9UJS0,P08574,O75431 11
Regulation of mrna stability by proteins that bind au rich elements 0.2250484721383067 0.0780807027021941 0.9377638573371057 1.0 1.0 64 O00233,P49721,Q9NQT4,Q16539,P20618 5
Downstream signaling events of b cell receptor bcr 0.22871267882791 0.0779848999021551 0.9378400645412232 1.0 1.0 44 O00233,P49721,O43242,P28074,P20618,P60900 6
Chromosome maintenance 0.2347091212313025 0.0778484732128938 0.9379485873681096 1.0 1.0 49 P84243,Q71F23,Q15554,P62805,P35244,P41440,P52434 7
Tcr signaling 0.2310956676729365 0.0774941301258528 0.9382304607142322 1.0 1.0 50 O00233,P49721,O43242,P28074,P20618,P60900 6
Hedgehog off state 0.2234102323958898 0.0772274434199235 0.9384426101436572 1.0 1.0 55 O00233,P49721,O43242,P28074,P20618,P17612,P60900 7
Nucleotide excision repair 0.2071811363201308 0.0770160352994749 0.938610788531689 1.0 1.0 56 P41440,Q9NR33,P52434 3
Fc epsilon receptor fceri signaling 0.1926470848718294 0.0769032850630123 0.938700484186612 1.0 1.0 56 O00233,P49721,P20618 3
Rhog gtpase cycle 0.1947472209131818 0.0757943823717027 0.9395826854883048 1.0 1.0 36 P50402,Q6IAA8,P60953,P42167,Q13190,Q86UP2,Q5T2T1,P51149,Q14739,O95202 10
Sensory perception 0.1724755419373359 0.0749612301455422 0.9402455589280734 1.0 1.0 27 P47755,P53582,P52907,P29375,Q9Y2J2,Q6IBS0,P17252,O14936,Q12965,Q6NUM9 10
Fcgamma receptor fcgr dependent phagocytosis 0.1651359920311062 0.0743150060463434 0.9407597369502436 1.0 1.0 34 Q9UQB8,Q96F07 2
Activation of rac1 0.3156393080604086 0.0715138660576374 0.942988789295381 1.0 1.0 5 Q16512,P63000 2
Processing and activation of sumo 0.3726124008228041 0.0661745061934127 0.9472388933850024 1.0 1.0 3 Q9UBT2,P61956 2
Sumo is transferred from e1 to e2 ube2i ubc9 0.3726124008228041 0.0661745061934127 0.9472388933850024 1.0 1.0 3 Q9UBT2,P61956 2
Sumo is conjugated to e1 uba2 sae1 0.3726124008228041 0.0661745061934127 0.9472388933850024 1.0 1.0 3 Q9UBT2,P61956 2
Ephrin signaling 0.3080366330341256 0.0612067043040663 0.9511945904831648 1.0 1.0 5 P63000,Q14155 2
Tryptophan catabolism 0.5452408930669731 0.0582128324288904 0.9535790992568562 1.0 1.0 2 Q6YP21 1
Vegfr2 mediated cell proliferation 0.3588010578900976 0.0549457586278517 0.9561816768031524 1.0 1.0 3 P17252,O43865 2
Pink1 prkn mediated mitophagy 0.271166199426258 0.0522730146696369 0.9583111550853638 1.0 1.0 8 O95140 1
Adenylate cyclase inhibitory pathway 0.3525400622829623 0.0504824908860069 0.9597379018617008 1.0 1.0 3 P63096 1
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.3520807071609527 0.050169768184628 0.9599871026981416 1.0 1.0 3 P20248 1
Caspase activation via dependence receptors in the absence of ligand 0.3473405818395543 0.0470573026444256 0.9624675571672524 1.0 1.0 3 P42574,Q9Y5V3 2
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.2962962962962988 0.0449605881186242 0.9641387232921376 1.0 1.0 4 Q96ST3,Q13547,P04179 3
G0 and early g1 0.2880809063098329 0.0420786060266517 0.9664360349802836 1.0 1.0 6 P06493,Q13547,P20248 3
Regulation of kit signaling 0.3344676140665502 0.0396115252820518 0.9684028388053414 1.0 1.0 3 P62993 1
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.2890350177000952 0.0392968489272275 0.9686537188693845 1.0 1.0 5 Q92696 1
Diseases of mismatch repair mmr 0.5017626321974052 0.0371938231404387 0.9703304636262536 1.0 1.0 2 P43246 1
Galactose catabolism 0.4994124559341852 0.0363548692246141 0.9709993995117816 1.0 1.0 2 P51570 1
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.2141384388807093 0.0296431443175733 0.9763516562290946 1.0 1.0 11 Q9UJX4,Q13042,Q9UJX3,Q16763,Q9UM13,Q13309,Q9UJX2,P30260,Q96DE5,Q9UJX6 10
Notch3 intracellular domain regulates transcription 0.2763080540858373 0.029552721973765 0.9764237712265008 1.0 1.0 4 Q06330,Q15398,P42224 3
Detoxification of reactive oxygen species 0.2421875626916484 0.0279205818004675 0.9777254929386934 1.0 1.0 9 P04179,P30041,P30048,P30044,P00390 5
Glucagon like peptide 1 glp1 regulates insulin secretion 0.2647037260378149 0.0275151534253781 0.9780488537377664 1.0 1.0 7 P46940,P17612 2
Pexophagy 0.4550528789659104 0.0249208131789258 0.98011812587266 1.0 1.0 2 P50542 1
Irf3 mediated activation of type 1 ifn 0.4377203290246768 0.0222661897535746 0.9822356188601497 1.0 1.0 2 Q9UHD2 1
Erythropoietin activates ras 0.2763853815295691 0.0205421345885318 0.9836109006174112 1.0 1.0 3 P62993 1
Repression of wnt target genes 0.2551440329218131 0.0180217573729618 0.9856214963551532 1.0 1.0 4 Q13363,Q13547,Q04726 3
Ptk6 regulates cell cycle 0.3569330199765004 0.0171545136036067 0.9863133497293906 1.0 1.0 2 P24941 1
Aquaporin mediated transport 0.253265210551153 0.0155995390904587 0.987553873391195 1.0 1.0 7 P17612,Q99797 2
Cyclin d associated events in g1 0.1908689248895459 0.0137520856936587 0.9890277689917488 1.0 1.0 11 Q13616,P63151,P63208,P42771,P11802,P30154,Q13309,P30153,Q00534,P24941 10
Ctla4 inhibitory signaling 0.2383695449845322 0.0109594753363948 0.9912557788798196 1.0 1.0 8 Q06124 1
Apoptosis induced dna fragmentation 0.2061248527679582 0.0076138321231496 0.9939250995945584 1.0 1.0 10 P52294,P42574,P10412,P09429,P16402,P07305,P16403,Q14974,O00273 9