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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/basic/plot_0.png +3 -0
- interpro_active_site/basic/plot_1.png +3 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +8 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/basic/plot_1.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +7 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/advanced/plot_0.png +3 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/basic/plot_3.png +3 -0
- interpro_conserved_site/basic/plot_4.png +3 -0
- interpro_conserved_site/basic/plot_5.png +3 -0
- interpro_conserved_site/basic/plot_6.png +3 -0
- interpro_conserved_site/basic/plot_7.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +2 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +41 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_12.png +3 -0
- interpro_domain/basic/plot_13.png +3 -0
- interpro_domain/basic/plot_14.png +3 -0
- interpro_domain/basic/plot_15.png +3 -0
- interpro_domain/basic/plot_16.png +3 -0
- interpro_domain/basic/plot_2.png +3 -0
- interpro_domain/basic/plot_3.png +3 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{"0": "Serine/threonine-protein kinase, active site [IPR008271]", "1": "Cysteine peptidase, cysteine active site [IPR000169]"}
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interpro_active_site/basic/plot_0.png
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Git LFS Details
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interpro_active_site/basic/plot_1.png
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interpro_active_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3401,
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"annotations_size": 56,
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"title": "Average number of proteins per term",
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"value": 2.9107142857142856
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C368/C368_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Serine carboxypeptidase, serine active site [IPR018202] 0.7988804407254992 1.0494366376342683 0.2939772032537298 0.999999996581398 0.6585089352883546 3 Q9HB40 1
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Protein-tyrosine phosphatase, active site [IPR016130] 0.4841710022259083 0.6869233133405004 0.4921310548374502 1.0 0.9534802985909532 6 Q06124,O60942 2
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Nucleoside diphosphate kinase, active site [IPR023005] 0.6751985878199505 0.2530334128072179 0.8002423934602643 1.0 0.9534802985909532 2 P22392 1
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ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.6634304207119777 0.229925892761987 0.8181493557673953 1.0 0.954507581728628 2 P53396 1
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Serine/threonine-protein kinase, active site [IPR008271] 0.2626140885548557 0.0450391346425377 0.964076115655362 1.0 1.0 53 Q16513,P19784,P48729,P53350,Q7KZI7,P68400,P17612,P06493,Q13131,O14965,O43683,P49840,O14976,Q96PY6,Q96SB4,Q13555,P11802,P24941,P54646,Q00534,Q96KB5,P28482 22
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Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.4192409532215423 0.0212599735202448 0.983038273119931 1.0 1.0 2 Q9NQ88 1
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Cysteine peptidase, cysteine active site [IPR000169] 0.2574374079528743 0.0145024562378624 0.9884291196758224 1.0 1.0 6 P07858,P17655,P07711,P07384,P53634 5
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interpro_active_site/selections.json
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{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP6", "CASP7", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "CTSL", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR14", "MTMR2", "NEK1", "NEK9", "NME1", "NME2", "PAK2", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "STK38", "SUCLG1", "TALDO1", "TAOK1", "TAOK2", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "ULK3", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["ACLY", "AURKA", "BUB1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK6", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSB", "CTSC", "CTSL", "GAK", "GSK3A", "MAPK1", "MARK2", "NEK1", "NME2", "PBK", "PKN2", "PLK1", "PRKAA1", "PRKAA2", "PRKACA", "PTPN11", "RNGTT", "SCPEP1", "SRPK1", "TIGAR"]}
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interpro_binding_site/advanced/idx2term.json
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{}
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interpro_binding_site/basic/idx2term.json
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{"0": "IQ motif, EF-hand binding site [IPR000048]", "1": "Beta tubulin, autoregulation binding site [IPR013838]"}
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interpro_binding_site/basic/plot_0.png
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interpro_binding_site/basic/plot_1.png
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interpro_binding_site/consensus.joblib
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oid sha256:2e7237e000eb11fbf0d048e9646c1fb4d935a3f86379c7b7a86f4f8773cdc70e
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3401,
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"annotations_size": 30,
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"title": "Average number of proteins per term",
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"value": 5.466666666666667
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C368/C368_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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IQ motif, EF-hand binding site [IPR000048] 0.5067426218211701 1.4698026902087336 0.1416152003525119 0.989756212634796 0.72325150326358 15 Q15386,Q15051,O43795,O94832,Q8IW35,Q12965 6
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Biotin-binding site [IPR001882] 0.6179080286863274 0.997059958280656 0.3187354074673041 0.9999900120919344 0.9061083227417908 4 Q96RQ3 1
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Peptidase M16, zinc-binding site [IPR001431] 0.5412246493279578 0.807764762111568 0.419226014047303 0.9999999167825016 0.9061083227417908 5 O43847,Q10713,P22695 3
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Beta tubulin, autoregulation binding site [IPR013838] 0.3464938126105046 0.2165241017455073 0.8285792402440493 1.0 0.9560529695123644 7 P04350,Q13885,Q9BVA1,P07437,Q9BUF5,Q13509 6
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Hexokinase, binding site [IPR019807] 0.5619299794057124 0.0862525677241831 0.9312656433665444 1.0 0.9633782517584945 2 P52789 1
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Inositol monophosphatase, metal-binding site [IPR020583] 0.3880553103854135 0.0183125165925943 0.985389542344488 1.0 0.985389542344488 2 O95861 1
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ASPM", "AURKA", "AURKB", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CEP97", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IMPA1", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "NEK1", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK38", "STK4", "TAOK1", "TAOK2", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["BPNT1", "CEP97", "HK2", "IQCB1", "MCCC1", "MYO1B", "MYO1D", "MYO1E", "NRDC", "PMPCA", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "UBE3C", "UQCRC2"]}
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{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}
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{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Ubiquitin specific protease, conserved site [IPR018200]", "2": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "3": "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "4": "Tubulin, conserved site [IPR017975]", "5": "Chaperonin TCP-1, conserved site [IPR002194]", "6": "Guanylate kinase, conserved site [IPR020590]", "7": "Tr-type G domain, conserved site [IPR031157]"}
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interpro_conserved_site/basic/plot_0.png
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interpro_conserved_site/basic/plot_1.png
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interpro_conserved_site/basic/plot_2.png
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interpro_conserved_site/basic/plot_5.png
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interpro_conserved_site/basic/plot_6.png
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:a9446d407bc765a1baa4a54aca441d68fd476fc99c667b9b7c6514c7f5c8312c
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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Proteasome beta-type subunit, conserved site [IPR016050] 5 8 2.5751005792447503 0.0100210941218568 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 1.0 0.0039921150854813 6.494328716879693e-05 2.339885859608748e-06
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3401,
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"annotations_size": 280,
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"title": "Average number of proteins per term",
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"value": 2.807142857142857
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}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C368/C368_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
|
| 2 |
+
Proteasome beta-type subunit, conserved site [IPR016050] 0.8254091760533182 2.5751005792447503 0.0100210941218568 0.9403976405020904 0.2070232643926836 8 P28070,P28072,P49721,P20618,P28074 5
|
| 3 |
+
Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.9332891325189656 2.299793089125721 0.0214599451773027 0.997698504746072 0.2070232643926836 4 P48735 1
|
| 4 |
+
DnaJ domain, conserved site [IPR018253] 0.5522474836910862 1.550704638111998 0.1209724825118316 0.9999999999999998 0.3984975894507397 11 Q96EY1,Q99543,P31689,Q96KC8 4
|
| 5 |
+
Syntaxin/epimorphin, conserved site [IPR006012] 0.6263409131287813 1.502627386770939 0.1329351570447063 1.0 0.4135760441390865 7 Q9P2W9,O60499,O43752 3
|
| 6 |
+
Ubiquitin specific protease, conserved site [IPR018200] 0.4777284607440706 1.229935155693484 0.2187213881214456 1.0 0.5723550343364932 14 Q9UPU5,Q14694,Q96RU2,Q86UV5,P51784,P40818,Q93008 7
|
| 7 |
+
Sterol reductase, conserved site [IPR018083] 0.9685201529861724 1.12269826173091 0.2615656665067902 1.0 0.631365401912942 2 Q9UBM7 1
|
| 8 |
+
Ribosomal protein L13, conserved site [IPR023563] 0.9482200647249196 1.0522005404701902 0.2927075515944226 1.0 0.6609525358583738 2 P40429 1
|
| 9 |
+
Ribosomal S11, conserved site [IPR018102] 0.9170344218887916 0.9452289979834064 0.3445419780985994 1.0 0.7461907378272841 2 P62263 1
|
| 10 |
+
Ras GTPase-activating protein, conserved site [IPR023152] 0.5779953523774036 0.8326229750642116 0.4050573973267324 1.0 0.8339417003785667 4 Q86VI3,P21359 2
|
| 11 |
+
Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.8717269785230962 0.7938306113675406 0.4272940493255976 1.0 0.8655063104366547 2 P15880 1
|
| 12 |
+
Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.5243733985679646 0.7361856818977863 0.4616177046280092 1.0 0.8930150308873944 5 P78527 1
|
| 13 |
+
Ribosomal protein L30, conserved site [IPR018038] 0.837599293909975 0.6841404502768584 0.4938864812062222 1.0 0.8930150308873944 2 P18124 1
|
| 14 |
+
Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.8049426301853506 0.5838344634461428 0.5593316890583595 1.0 0.8959035761416525 2 Q07812 1
|
| 15 |
+
Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.8049426301853506 0.5838344634461428 0.5593316890583595 1.0 0.8959035761416525 2 Q07812 1
|
| 16 |
+
Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.8049426301853506 0.5838344634461428 0.5593316890583595 1.0 0.8959035761416525 2 Q07812 1
|
| 17 |
+
Cullin, conserved site [IPR016157] 0.475834421867096 0.5388310069896708 0.5900034664212492 1.0 0.8959035761416525 5 Q93034 1
|
| 18 |
+
Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.7896440129449859 0.5387289077675808 0.5900739240720774 1.0 0.8959035761416525 2 Q00796 1
|
| 19 |
+
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.3588911915388715 0.4927450907186936 0.622192712996581 1.0 0.906046142289318 13 Q9H2U1,Q7L2E3,Q7Z478,Q8IX18,P54132,O60231 6
|
| 20 |
+
GTP1/OBG, conserved site [IPR006074] 0.7687555163283342 0.4793768413954207 0.6316705655891832 1.0 0.906046142289318 2 Q9Y295 1
|
| 21 |
+
HMG box A DNA-binding domain, conserved site [IPR017967] 0.589464390818132 0.3652110254609862 0.7149538887682358 1.0 0.964089639643672 3 O15347,P26583 2
|
| 22 |
+
Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.582695703354915 0.3474749548436568 0.7282345308884093 1.0 0.9708215156755792 3 Q9BXS5,Q96CW1 2
|
| 23 |
+
Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.3204945865319756 0.3210692655768839 0.7481579007776507 1.0 0.9864573376571928 14 Q5JPH6,Q5ST30,P26640,P47897,Q9Y2Z4,Q15031 6
|
| 24 |
+
Hexapeptide transferase, conserved site [IPR018357] 0.6916740217711125 0.2875531363480412 0.773688822038056 1.0 0.9881492822303748 2 Q96IJ6 1
|
| 25 |
+
Clathrin adaptor complex, small chain [IPR000804] 0.3902412104263431 0.2453976876386182 0.8061485192830982 1.0 0.991223817259433 5 P61923 1
|
| 26 |
+
ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.6634304207119777 0.229925892761987 0.8181493557673953 1.0 0.991223817259433 2 P53396 1
|
| 27 |
+
Polyamine biosynthesis domain, conserved site [IPR030373] 0.661959399823481 0.2271300401474805 0.8203226257395764 1.0 0.991223817259433 2 P19623 1
|
| 28 |
+
Tubulin, conserved site [IPR017975] 0.3464938126105046 0.2165241017455073 0.8285792402440493 1.0 0.991223817259433 7 P04350,Q13885,Q9BVA1,P07437,Q9BUF5,Q13509 6
|
| 29 |
+
DNA ligase, ATP-dependent, conserved site [IPR016059] 0.6507796410709071 0.2065625308492514 0.8363515251591742 1.0 0.9922814705278338 2 P18858 1
|
| 30 |
+
Chaperonin TCP-1, conserved site [IPR002194] 0.3309755378720924 0.2004405461651355 0.8411360515928075 1.0 0.9937472339493084 8 P17987,P49368,Q99832,P40227,P48643,P78371,P50990 7
|
| 31 |
+
S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082] 0.6343042071197452 0.1784700362487356 0.8583538510155138 1.0 0.9997366830956418 2 O43865 1
|
| 32 |
+
3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.5931156222418401 0.1198737657601566 0.9045831464848646 1.0 1.0 2 P40939 1
|
| 33 |
+
Guanylate kinase, conserved site [IPR020590] 0.3148748159057461 0.1009270702100697 0.9196083539036046 1.0 1.0 6 Q5T2T1,Q00013,Q14168,O14936,Q9NZW5 5
|
| 34 |
+
RNA polymerase, beta subunit, conserved site [IPR007121] 0.5639894086496076 0.0882013215539918 0.929716666964441 1.0 1.0 2 Q9H9Y6 1
|
| 35 |
+
Polyprenyl synthetase, conserved site [IPR033749] 0.5269196822594933 0.0585392561271707 0.9533190942242158 1.0 1.0 2 P14324 1
|
| 36 |
+
Inositol monophosphatase, conserved site [IPR020550] 0.3881695114773366 0.0429751201929511 0.9657213667355844 1.0 1.0 3 Q9NX62,O95861 2
|
| 37 |
+
Actin/actin-like conserved site [IPR020902] 0.3864037669217153 0.0419745478884043 0.9665189880725712 1.0 1.0 3 P61160,P61163 2
|
| 38 |
+
Tr-type G domain, conserved site [IPR031157] 0.2727540500736399 0.0315137974647554 0.9748597888248296 1.0 1.0 6 P13639,Q05639,P15170,P49411,Q96RP9 5
|
| 39 |
+
Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.4189467490438422 0.0212223899141683 0.9830682537347502 1.0 1.0 2 Q9UBT2 1
|
| 40 |
+
GHMP kinase, ATP-binding, conserved site [IPR006203] 0.3704030597234546 0.0173578149265658 0.986151162892297 1.0 1.0 2 Q03426 1
|
| 41 |
+
Profilin conserved site [IPR027310] 0.3695204471903563 0.0173199937750645 0.9861813352693334 1.0 1.0 2 P07737 1
|
interpro_conserved_site/selections.json
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GPCR, family 2, secretin-like, conserved site [IPR017983]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubby, C-terminal, conserved site [IPR018066]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0012, conserved site [IPR001110]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADGRE5", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARRB2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRPF3", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD63", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD2", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHA7", "EPN1", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGF1R", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "ING5", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NIT1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK1", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SGSH", "SLC1A5", "SLC27A4", "SLC4A2", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TULP3", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACLY", "ACTR1A", "ACTR2", "AHCYL1", "AP1M1", "AP2M1", "BAX", "BLM", "BPNT1", "CASK", "CCT2", "CCT3", "CCT5", "CCT6A", "CCT7", "CCT8", "COPZ1", "CUL5", "DHCR7", "DHX16", "DHX29", "DHX30", "DHX36", "DHX40", "DNAJA1", "DNAJA3", "DNAJC1", "DNAJC2", "DRG1", "EARS2", "EEF1A2", "EEF2", "FDPS", "GFM1", "GMPPA", "GSPT1", "HADHA", "HMGB2", "HMGB3", "IDH2", "IMPAD1", "IQGAP3", "LARS2", "LIG1", "MPP1", "MPP2", "MPP6", "MPP7", "MVK", "NF1", "PFN1", "POLR1B", "PRKDC", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "QARS", "RPL13A", "RPL7", "RPS14", "RPS2", "SORD", "SRM", "STX10", "STX18", "STX6", "TCP1", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUFM", "UBA2", "USP10", "USP11", "USP24", "USP28", "USP48", "USP8", "USP9X", "VARS1", "VARS2", "YARS2"]}
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{"0": "GTP binding domain [IPR006073]", "1": "DnaJ domain [IPR001623]", "2": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "3": "Small GTP-binding protein domain [IPR005225]", "4": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "5": "Ubiquitin specific protease domain [IPR028889]", "6": "Helicase-associated domain [IPR007502]", "7": "Domain of unknown function DUF1605 [IPR011709]", "8": "Peptidase M16, N-terminal [IPR011765]", "9": "Peptidase M16, C-terminal [IPR007863]", "10": "Importin-beta, N-terminal domain [IPR001494]", "11": "AP complex, mu/sigma subunit [IPR022775]", "12": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "13": "Tubulin/FtsZ, GTPase domain [IPR003008]", "14": "Aminotransferase, class I/classII [IPR004839]", "15": "Aminoacyl-tRNA synthetase, class II [IPR006195]", "16": "Peptidase M24 [IPR000994]"}
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