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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:506f13afef7dd824de91423fc6c7017bc7a0c091eae8efb1fe6f899f3b0f1e6d
+size 58875

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2627,
+    "annotations_size": 52,
+    "title": "Average number of proteins per term",
+    "value": 2.25
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C370/C370_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,11 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Histidine acid phosphatase active site [IPR033379]	0.9516190476190484	1.4430298762747569	0.1490120552924962	0.9997730045217064	0.5960482211699851	2	Q9NPH0	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.8102134146341525	1.3630509841981076	0.1728664430066726	0.9999482472643472	0.6420753597390698	3	Q9H3G5,P10619	2
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.5531620776605327	1.071372571584951	0.2840019406219154	0.9999999714624984	0.8204500506855334	6	P61081,P61086,P61088,P49427	4
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.5931945200144094	0.8962264338643415	0.3701318404565401	0.99999999996361	0.8443714704254991	4	P21281	1
+Serine/threonine-protein kinase, active site [IPR008271]	0.3534846735644186	0.5586815878281484	0.5763790473301575	1.0	0.9082336503384302	31	P06493,P49841,Q8TD19,P24941,Q13555,O14976,P31751,P11802	8
+Thiolase, active site [IPR020610]	0.4885746554899758	0.504852468060214	0.6136624609233721	1.0	0.9117270848004384	4	Q9BWD1	1
+Nucleoside diphosphate kinase, active site [IPR023005]	0.6186666666666734	0.2880838309466565	0.7732825692450302	1.0	0.939278197700648	2	P15531	1
+Peptidase S9, serine active site [IPR002471]	0.5996190476190547	0.2453705486639342	0.8061695308447174	1.0	0.939278197700648	2	P48147	1
+L-lactate dehydrogenase, active site [IPR018177]	0.5691428571428649	0.1859446890088749	0.852488136510539	1.0	0.939278197700648	2	P00338	1
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.3424563230986163	0.0728878214719536	0.9418953852230794	1.0	0.9497475990378312	3	P00390	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK2G", "CASP2", "CDC34", "CDK1", "CDK12", "CDK2", "CDK4", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "YES1"], "leading_proteins": ["ACAT2", "ACP6", "AKT2", "ATP6V1B2", "CAMK2G", "CDC34", "CDK1", "CDK2", "CDK4", "CPVL", "CTSA", "GAK", "GSK3B", "GSR", "LDHA", "NEK9", "NME1", "PREP", "UBE2K", "UBE2M", "UBE2N"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/basic/idx2term.json

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+{}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:9f4fd18a6d7c6967beda09887fc35efe66205498f4c31765a5c01acbf75b82f2
+size 57863

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2627,
+    "annotations_size": 28,
+    "title": "Average number of proteins per term",
+    "value": 4.142857142857143
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C370/C370_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.6178106509842469	1.2040563565072695	0.2285677969701995	0.9993012249330984	0.9142711878807984	5	Q13509,Q13885,Q9BUF5	3
+Biotin-binding site [IPR001882]	0.6431566908120475	1.098555596068635	0.2719619549766361	0.999861861704056	0.9518668424182264	4	Q96RQ3,P05165,P11498	3
+Protein kinase, ATP binding site [IPR017441]	0.3017858685609621	0.298040657485459	0.7656721327211966	1.0	0.9759075208556236	33	P24941,P49841,P06493,P31751	4
+Peptidase M16, zinc-binding site [IPR001431]	0.3753768609753193	0.2658770000964786	0.7903339390069966	1.0	0.9759075208556236	5	O43847,P22695,O75439	3
+Hexokinase, binding site [IPR019807]	0.5474285714285794	0.1504464647884006	0.8804123848037313	1.0	0.9759075208556236	2	P19367	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK2G", "CDK1", "CDK12", "CDK2", "CDK4", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAP4K5", "MAPK1", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TKT", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["AKT2", "CDK1", "CDK2", "GSK3B", "HK1", "MCCC1", "NRDC", "PC", "PCCA", "PMPCB", "TUBB2A", "TUBB3", "TUBB6", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "14-3-3 protein, conserved site [IPR023409]", "2": "WD40 repeat, conserved site [IPR019775]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:f7e4ad227c9c028a5fc5d0b05fc87cc2869bc67fe01f8b207b729ab8bf4b027f
+size 66882

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	7	8	2.611199786418495	0.0090225167100419	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.0479914252810258	1.7486004913858212e-06	1.828578586842436e-06	1.22573214543153e-09
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	1	6	2.398946146302624	0.0164423326995861	2.813106796116505	7.288834951456311	-0.5861883336862886	0.343247888518411	1.6359205295141483	0.5883757483977968	1.1482455180262974	0.2604113174624136	0.0012601973854463	0.0049445172385496	0.027832231049335	0.0140894483762481

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2627,
+    "annotations_size": 251,
+    "title": "Average number of proteins per term",
+    "value": 2.4262948207171315
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C370/C370_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,29 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.8350515463917672	2.611199786418495	0.0090225167100419	0.8971958949014806	0.465737072234933	8	P28074,P28072,P20618,P49720,P49721,Q99436,P28070	7
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.844870282600105	2.3989461463026234	0.0164423326995861	0.9844132024281332	0.465737072234933	6	P49419	1
+Ubiquitin specific protease, conserved site [IPR018200]	0.6877020654800508	1.9270373966415613	0.0539749695925562	0.999999105543012	0.465737072234933	8	O94966,Q86UV5,Q93009,Q96K76	4
+Annexin repeat, conserved site [IPR018252]	0.65380342113745	1.5410076144990847	0.123314932780397	0.9999999999999954	0.6274875509217432	6	P50995,P09525,P20073,P08133	4
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.6092474277191094	1.3331878179987464	0.1824701760441391	1.0	0.7028678981088294	6	P30837	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.6938482981415097	1.3072511911372715	0.1911274149231387	1.0	0.7028678981088294	4	Q13363,P56545	2
+Tubulin, conserved site [IPR017975]	0.6178106509842469	1.2040563565072695	0.2285677969701995	1.0	0.7540545991504708	5	Q13509,Q13885,Q9BUF5	3
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.6529710894506642	1.1388043324810506	0.2547847743714084	1.0	0.789518251447204	4	P48735	1
+Polyamine biosynthesis domain, conserved site [IPR030373]	0.8697142857142874	1.1224773288031988	0.2616595416963891	1.0	0.7924867478934499	2	P52788	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.8598095238095265	1.084235776894314	0.2782602725265901	1.0	0.798234159285004	2	P04066	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.7069008583249938	0.967119398523848	0.3334843491097843	1.0	0.8365672367216175	3	Q9Y2T2	1
+Ubiquitin conserved site [IPR019954]	0.8125714285714333	0.90478720296029	0.3655781324902716	1.0	0.8418358830739282	2	P46379	1
+Profilin conserved site [IPR027310]	0.7634285714285757	0.7257329545512792	0.4680024952659625	1.0	0.9100304508952956	2	P07737	1
+AMP-binding, conserved site [IPR020845]	0.4895211453726106	0.6566405710240159	0.5114120553549948	1.0	0.9556713313122928	5	P33121	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.4521283894076209	0.6193359304007235	0.5356950790431283	1.0	0.9556713313122928	6	P33991,P33992,P33993	3
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.706666666666671	0.5342297428053617	0.5931825935966235	1.0	0.9605731031790484	2	Q13363	1
+Thiolase, conserved site [IPR020613]	0.4549295495868821	0.5231375152826274	0.6008785604300215	1.0	0.9667981965893296	5	Q9BWD1	1
+Alpha-D-phosphohexomutase, conserved site [IPR016066]	0.6590476190476244	0.3918349063851849	0.6951802016799298	1.0	0.9859629873416188	2	Q96G03	1
+Intermediate filament protein, conserved site [IPR018039]	0.345637428452092	0.2793972899651574	0.7799399506036249	1.0	0.9859629873416188	7	Q16352,P08670,P07197	3
+Zinc finger, RING-type, conserved site [IPR017907]	0.3314302830966914	0.2370649348998833	0.8126064149221275	1.0	0.9859629873416188	7	Q14527	1
+Acyl-CoA dehydrogenase, conserved site [IPR006089]	0.3469465440823925	0.1967066943192096	0.8440570711399598	1.0	0.9859629873416188	5	P49748	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.5721904761904839	0.1913836620982742	0.8482250192423484	1.0	0.9859629873416188	2	P13861	1
+IMP dehydrogenase / GMP reductase, conserved site [IPR015875]	0.5577142857142938	0.1665511399303369	0.8677232412658527	1.0	0.9859629873416188	2	P12268	1
+Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]	0.5523809523809606	0.1580415677310908	0.8744240439803925	1.0	0.9859629873416188	2	Q9NQW7	1
+GTP1/OBG, conserved site [IPR006074]	0.5478095238095322	0.1510202546090794	0.8799597382780946	1.0	0.9859629873416188	2	Q9Y295	1
+Actin, conserved site [IPR004001]	0.5299047619047708	0.1259143118522533	0.8997997536249203	1.0	0.9859629873416188	2	O96019	1
+14-3-3 protein, conserved site [IPR023409]	0.2850057230064813	0.108308939064131	0.9137506319840688	1.0	0.9859629873416188	6	P31946,P63104,Q04917,P62258,P27348	5
+WD40 repeat, conserved site [IPR019775]	0.1850600074746781	0.0665357468134023	0.9469512989102196	1.0	0.986243883927241	36	Q9UFC0,Q13685,Q8NFH4,Q9GZS3,Q9NRG9,Q9BZH6,Q9BQA1	7

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARHGEF7", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CETN2", "CHAF1B", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX6", "DHCR7", "DHFR", "DHRS11", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPDR1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "KDSR", "KIF11", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MPI", "MPP6", "MPST", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NEFM", "NES", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NVL", "OSBPL11", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASA1", "RCL1", "RDH13", "RDX", "RIDA", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5L1", "SPTBN1", "SRM", "STMN1", "STOM", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "TAP2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "USP10", "USP14", "USP19", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["AAAS", "AAMP", "ACADVL", "ACAT2", "ACSL1", "ACTL6A", "ALDH1B1", "ALDH7A1", "ANXA11", "ANXA4", "ANXA6", "ANXA7", "AP3M1", "BAG6", "CTBP1", "CTBP2", "DRG1", "FUCA1", "HLTF", "IDH2", "IMPDH2", "INA", "LRWD1", "MCM4", "MCM5", "MCM7", "NEFM", "NUP37", "PFN1", "PGM2", "PRKAR2A", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "SMS", "TUBB2A", "TUBB3", "TUBB6", "USP19", "USP47", "USP48", "USP7", "VIM", "WDR11", "WDR61", "WDR77", "XPNPEP1", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

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+{}

interpro_domain/basic/idx2term.json

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+{"0": "Importin-beta, N-terminal domain [IPR001494]", "1": "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "2": "ATP-grasp fold [IPR011761]", "3": "Ubiquitin-like domain [IPR000626]", "4": "Proteasome component (PCI) domain [IPR000717]", "5": "PDZ domain [IPR001478]", "6": "Protein kinase domain [IPR000719]", "7": "TGS [IPR004095]", "8": "EF-hand domain [IPR002048]", "9": "Aminoacyl-tRNA synthetase, class II [IPR006195]", "10": "14-3-3 domain [IPR023410]", "11": "Small GTP-binding protein domain [IPR005225]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:3a7cac493c9d60fa18a80c06196b71934d91b54261230d03d15ffc76151a30ca
+size 118466

interpro_domain/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	1	5	2.272008829108122	0.0230859770670877	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.000647621121882	0.0025659780541994	0.0148625463558957	0.0544194668097373
+Aminopeptidase N-like , N-terminal domain [IPR045357]	1	5	2.272008829108122	0.0230859770670877	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.000647621121882	0.0025659780541994	0.0148625463558957	0.0544194668097373
+Aldehyde dehydrogenase domain [IPR015590]	1	8	2.25280748340785	0.0242712901521728	3.2985436893203883	9.529126213592232	-0.5613485854973601	0.3657232034282902	1.9683657938952	0.6908740865654212	1.1218179525542225	0.2726859723953302	0.0020655426456597	0.0080257871552124	0.0439142352380576	0.0278921605814954

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2627,
+    "annotations_size": 2268,
+    "title": "Average number of proteins per term",
+    "value": 2.0388007054673722
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C370/C370_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,195 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+BAR domain [IPR004148]	0.9598482851378108	2.376119077095216	0.017495815665083	1.0	0.5660427446619389	4	Q9NR46	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8652701709073737	2.272008829108122	0.0230859770670877	1.0	0.5660427446619389	5	P55786	1
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8652701709073737	2.272008829108122	0.0230859770670877	1.0	0.5660427446619389	5	P55786	1
+Aldehyde dehydrogenase domain [IPR015590]	0.7565129510488069	2.25280748340785	0.0242712901521728	1.0	0.5660427446619389	8	P49419	1
+PWWP domain [IPR000313]	0.7438446455390498	1.9536335771484192	0.0507445667523507	1.0	0.5660427446619389	6	P51858,O96028	2
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.7812050683059231	1.9183152390618905	0.0550710512819954	1.0	0.5660427446619389	5	P42694	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8368280594738956	1.8922922772813648	0.0584520493282885	1.0	0.5660427446619389	4	Q9UMX5,O43169,O15173	3
+Ubiquitin specific protease domain [IPR028889]	0.6549375079257944	1.8806230784636933	0.060023210067216	1.0	0.5660427446619389	9	O94966,Q86UV5,Q93009,Q96K76	4
+Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]	0.6549375079257944	1.8806230784636933	0.060023210067216	1.0	0.5660427446619389	9	O94966,Q86UV5,Q93009,Q96K76	4
+ERAP1-like C-terminal domain [IPR024571]	0.9343289440440292	1.8407884028177128	0.0656525729697314	1.0	0.5660427446619389	3	P55786	1
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.822303600189529	1.8337503920016152	0.0666910546323724	1.0	0.5660427446619389	4	Q8N8N7	1
+Importin-beta, N-terminal domain [IPR001494]	0.5879420991647801	1.7933303195032826	0.0729201221082118	1.0	0.5660427446619389	12	O15397,O00410,P55060,Q8TEX9,Q9UIA9,Q92973,Q9HAV4,Q96P70	8
+DNA2/NAM7 helicase, helicase domain [IPR041677]	0.7887009787290049	1.6973406453398232	0.0896322770581441	1.0	0.5692733166027264	4	P42694	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.8803770531303601	1.6341480207046075	0.1022277737866872	1.0	0.5762706662632927	3	P51114	1
+Fxr1, tudor domain [IPR041560]	0.8803770531303601	1.6341480207046075	0.1022277737866872	1.0	0.5762706662632927	3	P51114	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.8803770531303601	1.6341480207046075	0.1022277737866872	1.0	0.5762706662632927	3	P51114	1
+Agenet-like domain [IPR008395]	0.8803770531303601	1.6341480207046075	0.1022277737866872	1.0	0.5762706662632927	3	P51114	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.5792632001818572	1.498387482615517	0.1340326066729922	1.0	0.6172861404100352	9	Q96AY3	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.843725857360212	1.492707794166846	0.1355136922559108	1.0	0.6182415307348186	3	Q06210	1
+Ubiquitin system component CUE [IPR003892]	0.8391768292682964	1.4751169003472175	0.1401811175420149	1.0	0.6246184176528287	3	Q9Y679,Q86UW6	2
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.9424761904761914	1.4070264624736013	0.1594195420744331	1.0	0.6459015440911737	2	P51114	1
+Importin-alpha, importin-beta-binding domain [IPR002652]	0.8194564852926125	1.3988180212369845	0.1618675607683151	1.0	0.6459015440911737	3	P52292	1
+Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]	0.6188477680274693	1.3780678039277527	0.1681823548664087	1.0	0.6479729057873032	6	O00763,P11498,Q13085,Q96RQ3,P05165	5
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.8079268292682963	1.3542040511836122	0.1756712869068692	1.0	0.6498905203083639	3	P52888,Q9BYT8	2
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.927238095238096	1.3470884903920783	0.1779517345501062	1.0	0.6498905203083639	2	Q9NUQ9	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.9203809523809544	1.3201552034972783	0.1867832048693665	1.0	0.6498905203083639	2	P23786	1
+Biotin carboxylase, C-terminal [IPR005482]	0.6434019832188943	1.3169730321512456	0.1878476642746185	1.0	0.6498905203083639	5	Q96RQ3,P11498,P05165,O00763	4
+Biotin carboxylase-like, N-terminal domain [IPR005481]	0.6434019832188943	1.3169730321512456	0.1878476642746185	1.0	0.6498905203083639	5	Q96RQ3,P11498,P05165,O00763	4
+Biotin carboxylation domain [IPR011764]	0.6434019832188943	1.3169730321512456	0.1878476642746185	1.0	0.6498905203083639	5	Q96RQ3,P11498,P05165,O00763	4
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]	0.6938482981415097	1.3072511911372715	0.1911274149231387	1.0	0.6498905203083639	4	Q13363,P56545	2
+D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]	0.6938482981415097	1.3072511911372715	0.1911274149231387	1.0	0.6498905203083639	4	Q13363,P56545	2
+Amine oxidase [IPR002937]	0.9158095238095249	1.3022165724547732	0.1928423614970533	1.0	0.6511464088806231	2	Q8NB78	1
+Mu homology domain [IPR028565]	0.6863363078234956	1.2762390338578702	0.2018710341506708	1.0	0.6580396842977635	4	Q9Y2T2	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.7865853658536657	1.2716959716655971	0.2034811624429107	1.0	0.6580396842977635	3	Q96RQ1,Q9Y282	2
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.7865853658536657	1.2716959716655971	0.2034811624429107	1.0	0.6580396842977635	3	Q96RQ1,Q9Y282	2
+R3H domain [IPR001374]	0.7862302317307623	1.2703244261894062	0.2039690908559646	1.0	0.6580396842977635	3	Q9H6S0	1
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.6178106509842469	1.2040563565072695	0.2285677969701995	1.0	0.6808988585165962	5	Q13509,Q13885,Q9BUF5	3
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.6178106509842469	1.2040563565072695	0.2285677969701995	1.0	0.6808988585165962	5	Q13509,Q13885,Q9BUF5	3
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.7606645404731065	1.171799570192452	0.2412775353059324	1.0	0.6918046145055053	3	Q96CP7	1
+OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]	0.6082196357789733	1.161816466645104	0.2453100238535839	1.0	0.6954511594531564	5	P27694,Q15046	2
+Peptidase M28 [IPR007484]	0.7572408536585438	1.1586459834688263	0.2466005171457963	1.0	0.6965005888999578	3	P02786,Q7Z2K6	2
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.6529710894506642	1.1388043324810506	0.2547847743714084	1.0	0.7090206972691465	4	P48735	1
+Zinc finger, CHHC-type [IPR012996]	0.7488567073170789	1.126487353561479	0.2599592905519645	1.0	0.7093438730381143	3	P31943,P52597	2
+HDGF-related, PWWP domain [IPR035496]	0.7479492560732963	1.1230115616582683	0.2614325841662901	1.0	0.7093438730381143	3	P51858	1
+Spermidine synthase, tetramerisation domain [IPR035246]	0.8697142857142874	1.1224773288031988	0.2616595416963891	1.0	0.7093438730381143	2	P52788	1
+Polyamine biosynthesis  domain [IPR030374]	0.8697142857142874	1.1224773288031988	0.2616595416963891	1.0	0.7093438730381143	2	P52788	1
+Zinc finger, MYND-type [IPR002893]	0.8693333333333365	1.1210034178984354	0.2622864075477231	1.0	0.7093438730381143	2	Q9H7B4	1
+Reticulon [IPR003388]	0.6441077496889881	1.1024508364066388	0.2702657209792674	1.0	0.719439736127909	4	O95197	1
+SET domain [IPR001214]	0.7399743800804033	1.0925109895155107	0.2746085627909371	1.0	0.7261635814844856	3	Q9H7B4	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.8598095238095265	1.084235776894314	0.2782602725265901	1.0	0.7264457276177387	2	P04066	1
+Exoribonuclease, phosphorolytic domain 1 [IPR001247]	0.6395144506348871	1.0836491697377917	0.2785203808996437	1.0	0.7264457276177387	4	Q5RKV6	1
+Peptidase M24 [IPR000994]	0.5509005610676041	1.06087565739633	0.2887464132726212	1.0	0.7354132876283966	6	Q9NQH7	1
+ATP-grasp fold [IPR011761]	0.4915856597585329	1.0494214433060225	0.2939841932512981	1.0	0.7421983003964896	9	O00763,Q13572,P11498,Q13085,Q96RQ3,P05165	6
+Legume-like lectin [IPR005052]	0.8457142857142875	1.0301341361522771	0.3029470427241063	1.0	0.7517329243963601	2	P49257	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.7233231707317125	1.0291311069944162	0.3034180703944473	1.0	0.7520788892400072	3	P07197,P08670	2
+Peptidase M14, carboxypeptidase A [IPR000834]	0.8346666666666702	0.9880329085074732	0.3231365315683865	1.0	0.7655368931968312	2	P16870	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.7031481339854282	0.9530308631562832	0.3405744335046483	1.0	0.7802250658470126	3	P33121	1
+LEM domain [IPR003887]	0.6055289853592263	0.9456562721851668	0.3443239326056542	1.0	0.7849264989422363	4	Q86XL3	1
+Saposin B type domain [IPR008139]	0.8171428571428586	0.9218946056426	0.3565835531813497	1.0	0.7952918946780924	2	P07602	1
+Pyruvate carboxyltransferase [IPR000891]	0.8140952380952395	0.9104824659757662	0.3625681246236221	1.0	0.7981668504323515	2	P35914	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.5931945200144094	0.8962264338643415	0.3701318404565401	1.0	0.8046141771255698	4	P21281	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.5931945200144094	0.8962264338643415	0.3701318404565401	1.0	0.8046141771255698	4	P21281	1
+Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]	0.5917094355635251	0.8903045929761987	0.3733023555817212	1.0	0.8046443855710856	4	Q15046	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.5904535541103002	0.8853020238819538	0.3759937587152309	1.0	0.8060055243536329	4	Q4J6C6,P48147	2
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.4891294389543894	0.8647974537737257	0.3871499689394899	1.0	0.810882637230077	7	P60900,P25788,P25789	3
+CAP Gly-rich domain [IPR000938]	0.6760859952639409	0.8525368708396983	0.3939161838367966	1.0	0.8114458718817935	3	Q99426	1
+Fumarylacetoacetase-like, C-terminal [IPR011234]	0.6721504839673633	0.838107249725082	0.4019704716233296	1.0	0.8206959615099665	3	P16930	1
+PIN domain [IPR002716]	0.7878095238095258	0.8133532686427491	0.416015544105204	1.0	0.8349763310005334	2	Q9Y2L1	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.7836190476190503	0.7981086321194472	0.4248074525718177	1.0	0.8443532388810043	2	Q9NVE7	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7798095238095261	0.7843133082805358	0.4328562924343315	1.0	0.8476374532926443	2	O43390	1
+ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]	0.7782857142857165	0.7788125772453235	0.4360901277558571	1.0	0.8476374532926443	2	Q14240	1
+Phosphoribosyltransferase domain [IPR000836]	0.4886220222831884	0.7771306769879376	0.4370816766036385	1.0	0.8476374532926443	6	Q06203,P11908	2
+Exosome complex component, N-terminal domain [IPR025721]	0.7725714285714311	0.7582762789613968	0.4482856048572567	1.0	0.8594351241050366	2	Q13868	1
+Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]	0.7718095238095279	0.7555492685422747	0.4499194822622332	1.0	0.8611117179499957	2	Q9Y678	1
+Coatomer subunit gamma, C-terminal [IPR032154]	0.7718095238095279	0.7555492685422747	0.4499194822622332	1.0	0.8611117179499957	2	Q9Y678	1
+BTB/POZ domain [IPR000210]	0.6451981707317151	0.7408382714654717	0.4587915069591102	1.0	0.8678391474422535	3	Q96CX2,Q08380	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6428193676293161	0.7323986944916105	0.4639252553916064	1.0	0.8710119861160294	3	Q9UL46	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6428193676293161	0.7323986944916105	0.4639252553916064	1.0	0.8710119861160294	3	Q9UL46	1
+Glutaredoxin [IPR002109]	0.6379573170731783	0.7152306531733706	0.4744665309030758	1.0	0.8791585719674639	3	P35754,Q16881	2
+Glutathione S-transferase, N-terminal [IPR004045]	0.4251287001326037	0.6458773633458832	0.5183587806516035	1.0	0.9127984642997397	8	P28161,P21266,P78417	3
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.4571435482802094	0.640468999058071	0.5218677373614502	1.0	0.9139279588543704	6	P49748,Q15067	2
+MCM OB domain [IPR033762]	0.4521283894076209	0.6193359304007235	0.5356950790431283	1.0	0.9139279588543704	6	P33991,P33992,P33993	3
+MCM N-terminal domain [IPR027925]	0.4521283894076209	0.6193359304007235	0.5356950790431283	1.0	0.9139279588543704	6	P33991,P33992,P33993	3
+MCM, AAA-lid domain [IPR041562]	0.4521283894076209	0.6193359304007235	0.5356950790431283	1.0	0.9139279588543704	6	P33991,P33992,P33993	3
+MCM domain [IPR001208]	0.4521283894076209	0.6193359304007235	0.5356950790431283	1.0	0.9139279588543704	6	P33991,P33992,P33993	3
+AMP-dependent synthetase/ligase [IPR000873]	0.4511627080060705	0.6152900206099017	0.5383632068031035	1.0	0.9139279588543704	6	Q4G176,P33121	2
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.6081943358481992	0.6128115579759373	0.5400009476573842	1.0	0.9160225499528402	3	Q8N4Q0	1
+Fibronectin type II domain [IPR000562]	0.7253333333333372	0.5949593265854858	0.5518706591809686	1.0	0.9262417425625664	2	P11717	1
+VHS domain [IPR002014]	0.6021341463414729	0.5925898716361947	0.5534556590237263	1.0	0.9262417425625664	3	Q9UJY5,O60784	2
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.473158116678208	0.5922669546171877	0.5536718405199834	1.0	0.9262417425625664	5	Q32P28	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.473158116678208	0.5922669546171877	0.5536718405199834	1.0	0.9262417425625664	5	Q32P28	1
+Exportin-2, central domain [IPR013713]	0.6006097560975706	0.5875404557713447	0.5568407882183835	1.0	0.9262417425625664	3	O15397,P55060	2
+Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]	0.471909455363221	0.5874397011346701	0.5569084366771766	1.0	0.9262417425625664	5	O94973,Q9UJY5,Q10567	3
+CARD domain [IPR001315]	0.7207619047619098	0.5798622755554727	0.5620074973473406	1.0	0.9283561573079158	2	P42575	1
+Ubiquitin-like domain [IPR000626]	0.3415014447375324	0.5760360221875024	0.5645908336994854	1.0	0.930590124150024	15	Q15813,P46379,Q9NRR5,Q86UV5,Q99426	5
+Serine-threonine protein phosphatase, N-terminal [IPR031675]	0.7158095238095274	0.5636681165588705	0.5729800198592241	1.0	0.9332787839809428	2	P62136	1
+RING-type zinc-finger, LisH dimerisation motif [IPR027370]	0.588109403367813	0.5467275538891739	0.5845659212507404	1.0	0.9389486610458068	3	O15344	1
+COMM domain [IPR017920]	0.7089523809523849	0.5415321212766202	0.5881408638199694	1.0	0.9393411246201788	2	Q9Y6G5	1
+Thiolase, C-terminal [IPR020617]	0.4549295495868821	0.5231375152826274	0.6008785604300215	1.0	0.9437621710909202	5	Q9BWD1	1
+Thiolase, N-terminal [IPR020616]	0.4549295495868821	0.5231375152826274	0.6008785604300215	1.0	0.9437621710909202	5	Q9BWD1	1
+Survival motor neuron [IPR010304]	0.7013333333333376	0.517343821042254	0.6049161689938183	1.0	0.9439221108796206	2	O75940	1
+ELMO domain [IPR006816]	0.699428571428576	0.5113660687095842	0.6090947498504571	1.0	0.944153243569626	2	Q8IZ81	1
+Proteasome component (PCI) domain [IPR000717]	0.3327170254380924	0.5084669743839441	0.6111258941842448	1.0	0.944153243569626	17	Q15008,P48556,Q99627,O43242,Q13098,Q9UNM6,O00231,Q9Y262,Q9UBW8,P61201	10
+GINS subunit, domain A [IPR021151]	0.5754573170731814	0.5065695305733863	0.61245689182274	1.0	0.944153243569626	3	Q9Y248,Q9BRT9	2
+Glutamine amidotransferase [IPR017926]	0.4866579897181408	0.4983766450648796	0.6182185949421117	1.0	0.9493024870201148	4	P17812	1
+PPM-type phosphatase domain [IPR001932]	0.5703823412287772	0.4908103509822722	0.6235605883238902	1.0	0.9535035976295064	3	Q15750	1
+GOLD domain [IPR009038]	0.3964912640188978	0.4596987349081751	0.6457324777147171	1.0	0.9597677915891972	7	Q9Y3B3	1
+RNA-binding domain, S1 [IPR022967]	0.3947110020761382	0.4527295915791401	0.6507434685766607	1.0	0.9597677915891972	7	P05198,Q14562,P62487	3
+Exportin-1/Importin-beta-like [IPR013598]	0.6792380952381003	0.4498115222788365	0.6528463489390917	1.0	0.9597677915891972	2	Q9HAV4	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6704761904761957	0.4241898965263472	0.6714273286086714	1.0	0.9616171184679088	2	Q92945	1
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.6697142857142909	0.4219948125466421	0.6730288038297645	1.0	0.9616171184679088	2	O75694	1
+PDZ domain [IPR001478]	0.3152817645342485	0.4202340530596333	0.674314480409536	1.0	0.9616171184679088	17	Q9Y4G8,Q6ZWJ1,O14641,Q9HD26,O43464,O14936	6
+FAD/NAD(P)-binding domain [IPR023753]	0.4252919467020806	0.4178233043314064	0.6760763108750334	1.0	0.9616171184679088	5	O95831	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.5407979622919596	0.4033482623249334	0.6866920420233371	1.0	0.9641871055280856	3	Q32P28	1
+PITH domain [IPR010400]	0.6601904761904814	0.3950144747054884	0.6928322055892671	1.0	0.9663409240756612	2	Q9GZP4	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]	0.6590476190476244	0.3918349063851849	0.6951802016799298	1.0	0.9663409240756612	2	Q96G03	1
+Alpha-D-phosphohexomutase, C-terminal [IPR005843]	0.6590476190476244	0.3918349063851849	0.6951802016799298	1.0	0.9663409240756612	2	Q96G03	1
+GHMP kinase N-terminal domain [IPR006204]	0.6556190476190532	0.382372508380467	0.7021850790625659	1.0	0.9704788295636194	2	P53602	1
+CARG-binding factor, N-terminal [IPR012956]	0.6533333333333388	0.3761284866736522	0.7068213773532195	1.0	0.9739191274830508	2	Q99729	1
+Peptidase S9A, N-terminal domain [IPR023302]	0.6529523809523865	0.375092857977131	0.7075914084334172	1.0	0.9743881689902796	2	P48147	1
+Helicase/UvrB, N-terminal [IPR006935]	0.6480000000000057	0.3617622035251414	0.7175297389895121	1.0	0.9807405265698904	2	P19447	1
+NOPS [IPR012975]	0.5228658536585491	0.3543869571823481	0.7230489078105795	1.0	0.9807405265698904	3	P23246,Q15233	2
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.6449523809523867	0.3536824862574452	0.7235768492657089	1.0	0.9807405265698904	2	Q96CX2	1
+Elongation factor EFG, domain V-like [IPR000640]	0.4277544796035016	0.3181106156708951	0.7504010314377894	1.0	0.9807405265698904	4	P13639,Q7Z2Z2,Q96RP9	3
+Elongation Factor G, domain II [IPR041095]	0.4277544796035016	0.3181106156708951	0.7504010314377894	1.0	0.9807405265698904	4	P13639,Q7Z2Z2,Q96RP9	3
+GAT domain [IPR004152]	0.6247619047619111	0.302624667606096	0.7621759134238018	1.0	0.9818822992024928	2	O60784	1
+SH3 domain [IPR001452]	0.3005503120118851	0.2997348116580535	0.7643794428710913	1.0	0.9818822992024928	27	Q9NR46,Q9Y371	2
+Nucleoside diphosphate kinase-like domain [IPR034907]	0.6186666666666734	0.2880838309466565	0.7732825692450302	1.0	0.9818822992024928	2	P15531	1
+Intermediate filament, rod domain [IPR039008]	0.345637428452092	0.2793972899651574	0.7799399506036249	1.0	0.9818822992024928	7	Q16352,P08670,P07197	3
+Protein kinase domain [IPR000719]	0.2887588740366641	0.2621991474229445	0.7931679106637892	1.0	0.9818822992024928	41	P06493,P49841,Q8TD19,P24941,Q13555,O14976,P31751,P11802	8
+Plectin/S10, N-terminal [IPR005326]	0.6026666666666736	0.2519220630506206	0.8011013056110725	1.0	0.9818822992024928	2	P46783	1
+Peptidase M16, N-terminal [IPR011765]	0.3364690330098764	0.2516300504247216	0.8013270289518135	1.0	0.9818822992024928	7	O43847,Q5JRX3,P22695,O75439	4
+Peptidase M16, C-terminal [IPR007863]	0.3364690330098764	0.2516300504247216	0.8013270289518135	1.0	0.9818822992024928	7	O43847,Q5JRX3,P22695,O75439	4
+Pentacotripeptide-repeat region of PRORP [IPR033443]	0.5984761904761976	0.2429418778510439	0.8080504233576695	1.0	0.9818822992024928	2	P42704	1
+S1 domain [IPR003029]	0.3447396763427727	0.2369125972513258	0.8127245969728327	1.0	0.9818822992024928	6	Q14562,P62487	2
+TIP49, P-loop domain [IPR010339]	0.5897142857142931	0.2248359005181694	0.8221069364282771	1.0	0.9818822992024928	2	Q9Y265	1
+RuvB-like, AAA-lid domain [IPR041048]	0.5897142857142931	0.2248359005181694	0.8221069364282771	1.0	0.9818822992024928	2	Q9Y265	1
+Sterile alpha motif domain [IPR001660]	0.3560510690571441	0.2173618127164199	0.8279263887817714	1.0	0.9818822992024928	5	Q9Y3Z3	1
+Band 7 domain [IPR001107]	0.3228149112871069	0.2133395441236686	0.8310621316863633	1.0	0.9818822992024928	7	P27105	1
+Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]	0.3469465440823925	0.1967066943192096	0.8440570711399598	1.0	0.9818822992024928	5	P49748	1
+Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]	0.3469465440823925	0.1967066943192096	0.8440570711399598	1.0	0.9818822992024928	5	P49748	1
+Cold-shock (CSD) domain [IPR019844]	0.3754239775582871	0.1954360933569876	0.8450515629401105	1.0	0.9818822992024928	4	P16989,O75534	2
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.5721904761904839	0.1913836620982742	0.8482250192423484	1.0	0.9818822992024928	2	P13861	1
+FAD dependent oxidoreductase [IPR006076]	0.4457156542913006	0.1854753933958861	0.8528561786362143	1.0	0.9818822992024928	3	Q9H9P8	1
+IMP dehydrogenase/GMP reductase [IPR001093]	0.5577142857142938	0.1665511399303369	0.8677232412658527	1.0	0.9818822992024928	2	P12268	1
+TGS [IPR004095]	0.312094620373903	0.1578878789066082	0.8745451494914027	1.0	0.9818822992024928	6	P26639,P55039,Q9NTK5,Q9Y295,Q9NYK5	5
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.2561271149062094	0.1525604929832325	0.8787448822372694	1.0	0.9818822992024928	11	P28161,P21266,P78417	3
+Cullin, N-terminal [IPR001373]	0.3089851159420007	0.1514559794706022	0.8796160334785155	1.0	0.9818822992024928	6	Q9UJX6	1
+Cullin homology domain [IPR016158]	0.3089851159420007	0.1514559794706022	0.8796160334785155	1.0	0.9818822992024928	6	Q9UJX6	1
+GTP binding protein, second domain [IPR031662]	0.5478095238095322	0.1510202546090794	0.8799597382780946	1.0	0.9818822992024928	2	Q9Y295	1
+Hexokinase, N-terminal [IPR022672]	0.5474285714285794	0.1504464647884006	0.8804123848037313	1.0	0.9818822992024928	2	P19367	1
+Hexokinase, C-terminal [IPR022673]	0.5474285714285794	0.1504464647884006	0.8804123848037313	1.0	0.9818822992024928	2	P19367	1
+6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]	0.4218750000000159	0.1482827051961004	0.8821196637227899	1.0	0.9818822992024928	3	P52209,P31937	2
+Gamma-adaptin ear (GAE) domain [IPR008153]	0.5348571428571516	0.1324805776622322	0.8946041843906787	1.0	0.9818822992024928	2	Q9UJY5	1
+Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]	0.5333333333333421	0.1304296999890801	0.896226470094557	1.0	0.9818822992024928	2	Q9H4A4	1
+CNNM, transmembrane domain [IPR002550]	0.5283809523809613	0.1239512919920739	0.9013538409114484	1.0	0.9818822992024928	2	Q6P4Q7	1
+Ion transporter-like, CBS domain [IPR044751]	0.5283809523809613	0.1239512919920739	0.9013538409114484	1.0	0.9818822992024928	2	Q6P4Q7	1
+EF-hand domain [IPR002048]	0.2426855553437738	0.1214966825903073	0.90329764214948	1.0	0.9818822992024928	36	P80303,Q9UBV8,Q96AY3,Q8NF37,Q14257	5
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.3050505238652812	0.1204025251231742	0.9041642911962982	1.0	0.9818822992024928	5	Q8IWA4	1
+Dynamin, N-terminal [IPR045063]	0.3050505238652812	0.1204025251231742	0.9041642911962982	1.0	0.9818822992024928	5	Q8IWA4	1
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.2654720387778866	0.1166631326504319	0.9071270066029984	1.0	0.9818822992024928	8	P61081,P49427	2
+YjeF N-terminal domain [IPR004443]	0.5219047619047711	0.115906404033433	0.9077267202230064	1.0	0.9818822992024928	2	Q8NCW5	1
+Copine, C2B domain [IPR037768]	0.5215238095238186	0.1154480831699348	0.9080899688564898	1.0	0.9818822992024928	2	O75131	1
+Copine, C-terminal [IPR010734]	0.5215238095238186	0.1154480831699348	0.9080899688564898	1.0	0.9818822992024928	2	O75131	1
+Aminotransferase, class I/classII [IPR004839]	0.2993897787948149	0.1124326091964066	0.9104804008382696	1.0	0.9818822992024928	5	O15269,P17174,P00505,O75600	4
+EB1, C-terminal [IPR004953]	0.5188571428571522	0.1122857861966847	0.9105968115003322	1.0	0.9818822992024928	2	Q15555	1
+Aminoacyl-tRNA synthetase, class II [IPR006195]	0.2347094801223264	0.1122259870803527	0.9106442246134718	1.0	0.9818822992024928	11	P26639,P41250,Q15046,Q9Y285,Q9NP81,P49591,Q9BW92,P14868,Q6PI48,O43776	10
+14-3-3 domain [IPR023410]	0.2850057230064813	0.108308939064131	0.9137506319840688	1.0	0.9818822992024928	6	P31946,P63104,Q04917,P62258,P27348	5
+Glutathione S-transferase, C-terminal [IPR004046]	0.2441124970799232	0.10397695853851	0.9171876338649538	1.0	0.9818822992024928	9	P78417	1
+CTLH, C-terminal LisH motif [IPR006595]	0.3778357077343445	0.0979907761008817	0.9219396177226502	1.0	0.9830555021132914	3	Q9H7D7	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.3071957081110792	0.0967248643926727	0.9229448934798756	1.0	0.9836649522614463	4	O00303	1
+Small GTP-binding protein domain [IPR005225]	0.22237680567995	0.0923848965996406	0.9263922388743216	1.0	0.985263975596344	37	P11233,Q9NR31,Q14964,P36404,P18085,P40616,P62820,P61106,P20338,Q9Y295,P51149,P51153,P60953,Q7Z2Z2,Q9Y6B6,P36405,P61020,Q9BW83	18
+Ricin B, lectin domain [IPR000772]	0.4986666666666763	0.0908831063652862	0.927585473801507	1.0	0.9853694869235682	2	Q10472	1
+Translation initiation factor, beta propellor-like domain [IPR013979]	0.364329268292699	0.0869609181550635	0.9307025771737742	1.0	0.9861667364517496	3	Q96J01,P55884	2
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.256525837136844	0.0829125784199165	0.9339210523477112	1.0	0.9870144206545244	7	Q7L5N1,O00303,O15372	3
+Rhodanese-like domain [IPR001763]	0.3551829268292823	0.0805358864256577	0.9358110556776756	1.0	0.9881456044863496	3	Q8NCN5,Q99956	2
+B-box-type zinc finger [IPR000315]	0.2793366463594411	0.0747942036483067	0.940378453719844	1.0	0.9924515277043304	4	O15344	1
+Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]	0.3424563230986163	0.0728878214719536	0.9418953852230794	1.0	0.9935901086911368	3	P00390	1
+Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]	0.3327172179481875	0.0679672421292528	0.9458117109553664	1.0	0.9954064781655552	3	Q16531	1
+Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]	0.3327172179481875	0.0679672421292528	0.9458117109553664	1.0	0.9954064781655552	3	Q16531	1
+B-box, C-terminal [IPR003649]	0.3247300944032607	0.0644810924945486	0.9485871617809424	1.0	0.997864416938394	3	O15344	1
+K Homology domain, type 1 [IPR004088]	0.1848363508978815	0.0616449614721228	0.9508455709279846	1.0	0.9993131394182896	22	P51114	1
+MIT domain [IPR007330]	0.3094512195122058	0.0590418531731761	0.952918772225575	1.0	1.0	3	O75351,Q8N0X7	2
+LEM-like domain [IPR013146]	0.4495238095238207	0.0555376398651748	0.955710143933652	1.0	1.0	2	P42167	1
+DNA mismatch repair protein MutS, clamp [IPR007861]	0.4240000000000093	0.0447575387163865	0.96430057034774	1.0	1.0	2	P43246	1
+MIRO domain [IPR020860]	0.4236190476190578	0.0446278588880736	0.9644039365951576	1.0	1.0	2	Q8IXI2	1
+EF hand associated, type-1 [IPR013566]	0.4236190476190578	0.0446278588880736	0.9644039365951576	1.0	1.0	2	Q8IXI2	1
+EF hand associated, type-2 [IPR013567]	0.4236190476190578	0.0446278588880736	0.9644039365951576	1.0	1.0	2	Q8IXI2	1
+3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]	0.4217142857142975	0.0439919064696789	0.9649108553249028	1.0	1.0	2	P31937	1
+ISWI, HAND domain [IPR015194]	0.4125714285714387	0.0412156978644438	0.9671239392203276	1.0	1.0	2	P28370	1
+SLIDE domain [IPR015195]	0.4125714285714387	0.0412156978644438	0.9671239392203276	1.0	1.0	2	P28370	1
+Methylglyoxal synthase-like domain [IPR011607]	0.4076190476190589	0.0398910710737587	0.9681799696894724	1.0	1.0	2	P27708	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.4060952380952502	0.039507213699191	0.9684860023082152	1.0	1.0	2	O15460	1
+Phospholipase/carboxylesterase/thioesterase [IPR003140]	0.3927619047619155	0.0365850415092718	0.970815870692481	1.0	1.0	2	O95372	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Proteasome B-type subunit [IPR023333]"}