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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +5 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +3 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +1 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +36 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_2.png +3 -0
- interpro_domain/basic/plot_3.png +3 -0
- interpro_domain/basic/plot_4.png +3 -0
- interpro_domain/basic/plot_5.png +3 -0
- interpro_domain/basic/plot_6.png +3 -0
- interpro_domain/consensus.joblib +3 -0
- interpro_domain/df_merge.tsv +2 -0
- interpro_domain/metrics.json +7 -0
- interpro_domain/paths.json +1 -0
- interpro_domain/result.tsv +164 -0
- interpro_domain/selections.json +0 -0
- interpro_family/advanced/idx2term.json +1 -0
- interpro_family/advanced/plot_0.png +3 -0
- interpro_family/advanced/plot_1.png +3 -0
- interpro_family/basic/idx2term.json +1 -0
- interpro_family/basic/plot_0.png +3 -0
- interpro_family/basic/plot_1.png +3 -0
- interpro_family/basic/plot_2.png +3 -0
- interpro_family/basic/plot_3.png +3 -0
- interpro_family/basic/plot_4.png +3 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{}
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interpro_active_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:537fba4a54d0094b9e53ed8dd2b7ef0daa025171d7e4a8102c9d3ca7f11b9d57
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size 61704
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2640,
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"annotations_size": 52,
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"title": "Average number of proteins per term",
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"value": 2.25
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C373/C373_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Serine carboxypeptidase, serine active site [IPR018202] 0.9442548350398172 1.524182563691577 0.1274631124264851 0.9991667843655884 0.6628081846177225 3 P10619,Q9HB40 2
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Histidine acid phosphatase active site [IPR033379] 0.8108415466262169 0.5336732943790957 0.5935675888546033 1.0 0.9916749953381448 2 P11117 1
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ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.4022877743277074 0.1879889739719608 0.850885294583076 1.0 0.9916749953381448 4 P21281 1
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Protein-tyrosine phosphatase, active site [IPR016130] 0.4201744406522544 0.0523142427478866 0.9582783047855832 1.0 0.9916749953381448 3 Q06124,P18031 2
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interpro_active_site/selections.json
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{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK2G", "CASP2", "CDC34", "CDK1", "CDK12", "CDK2", "CDK4", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "YES1"], "leading_proteins": ["ACP2", "ATP6V1B2", "CTSA", "PTPN1", "PTPN11", "SCPEP1"]}
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interpro_binding_site/advanced/idx2term.json
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{}
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interpro_binding_site/basic/idx2term.json
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{}
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interpro_binding_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:0e0e3f73aa6761af9c5fc13ab16eade9115544b5b8cc4f149877d0065bcf6d8d
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size 59406
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2640,
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"annotations_size": 28,
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"title": "Average number of proteins per term",
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"value": 4.142857142857143
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C373/C373_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Peptidase M16, zinc-binding site [IPR001431] 0.6822561498992994 1.3565761092720732 0.1749159371033544 0.9954085531912914 0.5027655014350544 5 Q10713 1
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Beta tubulin, autoregulation binding site [IPR013838] 0.5023685968973928 0.5898857327943613 0.5552672598403756 0.9999999998597914 0.9145578397370894 5 Q13885,Q9BUF5 2
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK2G", "CDK1", "CDK12", "CDK2", "CDK4", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAP4K5", "MAPK1", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TKT", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["PMPCA", "TUBB2A", "TUBB6"]}
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interpro_conserved_site/advanced/idx2term.json
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{}
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interpro_conserved_site/basic/idx2term.json
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{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "14-3-3 protein, conserved site [IPR023409]"}
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interpro_conserved_site/basic/plot_0.png
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Git LFS Details
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interpro_conserved_site/basic/plot_1.png
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Git LFS Details
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:1615a53e7b28f51ecf1cd2a82c210857464a44c5018458b445906c6e67b65d0d
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size 67646
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2640,
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"annotations_size": 251,
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"title": "Average number of proteins per term",
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"value": 2.4382470119521913
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}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C373/C373_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Proteasome beta-type subunit, conserved site [IPR016050] 0.7590014425773498 1.8562872432217103 0.063412626414568 0.9999999277857414 0.4804593948699259 8 P28074,P20618,P28072,P28070,P49720,P49721 6
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Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.7116124314276316 1.7037452287863857 0.0884286944234165 0.9999999999191924 0.4932356066728342 6 P51648 1
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Thiolase, conserved site [IPR020613] 0.6899145504363189 1.3900227366213045 0.1645219732256142 1.0 0.5899287897089882 5 P22307 1
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Syntaxin/epimorphin, conserved site [IPR006012] 0.61930013037624 1.2788844064131224 0.2009377646207806 1.0 0.6384225179723536 6 Q9P2W9,Q13190,Q86Y82 3
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Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.6424173281390937 1.2120453920397911 0.2254950053997153 1.0 0.6581307715735879 12 Q9Y394,Q06136,Q53GQ0,Q8NBN7 4
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Enoyl-CoA hydratase/isomerase, conserved site [IPR018376] 0.5862495429017651 1.1252235044745102 0.2604943354238143 1.0 0.7115448588164092 6 Q13011 1
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D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.6683311646075517 1.1037712331412408 0.2696923865386038 1.0 0.7201360534169102 4 P56545,Q13363 2
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Haem oxygenase conserved site [IPR018207] 0.953752843062923 0.9864682927217748 0.3239033670934275 1.0 0.7560811778106171 2 P30519 1
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Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.5556904789073409 0.9835724719570484 0.3253257657511819 1.0 0.7560811778106171 6 P51648 1
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3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.7467879680782479 0.7937465259658705 0.4273430087298602 1.0 0.9011199312079016 3 P40939 1
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Glycoside hydrolase, family 29, conserved site [IPR018526] 0.8938589840788482 0.7877989595804026 0.4308143097408294 1.0 0.9011199312079016 2 Q9BTY2 1
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| 13 |
+
Zinc finger, RING-type, conserved site [IPR017907] 0.480227380819866 0.6179301476452701 0.5366213851286918 1.0 0.9544679734712588 7 Q14527 1
|
| 14 |
+
Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.8309325246398773 0.5921769271580484 0.5537321180838217 1.0 0.9544679734712588 2 Q99536 1
|
| 15 |
+
Tubulin, conserved site [IPR017975] 0.5023685968973928 0.5898857327943613 0.5552672598403756 1.0 0.9544679734712588 5 Q13885,Q9BUF5 2
|
| 16 |
+
Mini-chromosome maintenance, conserved site [IPR018525] 0.4646642537298897 0.5761395161709618 0.5645208834989219 1.0 0.9544679734712588 6 Q14566 1
|
| 17 |
+
Intermediate filament protein, conserved site [IPR018039] 0.4425541073155288 0.4614126732111454 0.6445025608268744 1.0 0.9897175034530924 7 P08670 1
|
| 18 |
+
Sterol reductase, conserved site [IPR018083] 0.7793783169067472 0.4468892327801011 0.6549550385487901 1.0 0.9897175034530924 2 Q9UBM7 1
|
| 19 |
+
Thioredoxin, conserved site [IPR017937] 0.4646004030491992 0.4385234253317007 0.6610068927986308 1.0 0.9897175034530924 12 Q9H3N1,Q9H1E5 2
|
| 20 |
+
Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.6220016629973228 0.3951700178606829 0.6927174180513285 1.0 0.9998482338488008 3 Q9Y2T2 1
|
| 21 |
+
14-3-3 protein, conserved site [IPR023409] 0.3933181473044798 0.2975024527753493 0.7660829356784049 1.0 1.0 6 Q04917,P31946,P61981,P62258,P63104 5
|
| 22 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752] 0.7009097801364632 0.2622021595853915 0.7931655885165361 1.0 1.0 2 Q13363 1
|
| 23 |
+
Polyamine biosynthesis domain, conserved site [IPR030373] 0.6902956785443495 0.2412478601070823 0.8093630190782208 1.0 1.0 2 P52788 1
|
| 24 |
+
Annexin repeat, conserved site [IPR018252] 0.3710606905534205 0.2238726088065006 0.8228564298049204 1.0 1.0 6 P20073 1
|
| 25 |
+
Fumarate lyase, conserved site [IPR020557] 0.6478392721758878 0.1680002899528181 0.8665830509718264 1.0 1.0 2 P07954 1
|
| 26 |
+
Cyclic nucleotide-binding, conserved site [IPR018488] 0.617892342683852 0.1266653001454541 0.8992053110425768 1.0 1.0 2 P10644 1
|
| 27 |
+
Ribosomal protein S2, conserved site [IPR018130] 0.6156178923426824 0.1238713626136533 0.9014171276062052 1.0 1.0 2 Q9Y399 1
|
| 28 |
+
Adenylate kinase, conserved site [IPR033690] 0.3594312026494467 0.1107560451823759 0.9118098016910424 1.0 1.0 4 P27144,P00568 2
|
| 29 |
+
Actin, conserved site [IPR004001] 0.5833965125094788 0.0893328971799224 0.9288173504069428 1.0 1.0 2 P61163 1
|
| 30 |
+
ABC transporter-like, conserved site [IPR017871] 0.311504435241469 0.0594886050301006 0.9525629412729392 1.0 1.0 7 P08183 1
|
| 31 |
+
Ribosomal protein S9, conserved site [IPR020574] 0.5413191811978805 0.0572963139044697 0.954309156609499 1.0 1.0 2 P62249 1
|
| 32 |
+
Clathrin adaptor complex, small chain [IPR000804] 0.3871824042472563 0.0355171349920688 0.9716673832473406 1.0 1.0 3 P53680,P61923 2
|
| 33 |
+
Profilin conserved site [IPR027310] 0.4689158453373788 0.0288669855154108 0.9769706763849222 1.0 1.0 2 P07737 1
|
| 34 |
+
Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.4454131918119791 0.0245836738339323 0.9803870417581512 1.0 1.0 2 Q96G03 1
|
| 35 |
+
Calreticulin/calnexin, conserved site [IPR018124] 0.3485020857034524 0.0244271046692689 0.9805119283734892 1.0 1.0 3 O14967,P27824 2
|
| 36 |
+
S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082] 0.3297952994692887 0.0183057345680082 0.985394952710278 1.0 1.0 2 O43865 1
|
interpro_conserved_site/selections.json
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARHGEF7", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CETN2", "CHAF1B", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX6", "DHCR7", "DHFR", "DHRS11", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPDR1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "KDSR", "KIF11", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MPI", "MPP6", "MPST", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NEFM", "NES", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NVL", "OSBPL11", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASA1", "RCL1", "RDH13", "RDX", "RIDA", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5L1", "SPTBN1", "SRM", "STMN1", "STOM", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "TAP2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "USP10", "USP14", "USP19", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ACTR1A", "AHCYL1", "AK1", "AK4", "ALDH3A2", "ANXA7", "AP2S1", "AP3M1", "CANX", "CLGN", "COPZ1", "CTBP1", "CTBP2", "DHCR7", "DHRS7", "ECH1", "FH", "FUCA2", "HADHA", "HLTF", "HMOX2", "HSD17B12", "KDSR", "MCM6", "MRPS2", "PFN1", "PGM2", "PRKAR1A", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "RDH13", "RPS16", "SCP2", "SMS", "STX12", "STX18", "STX5", "TMX1", "TMX4", "TUBB2A", "TUBB6", "VAT1", "VIM", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ"]}
|
interpro_domain/advanced/idx2term.json
ADDED
|
@@ -0,0 +1 @@
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| 1 |
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{}
|
interpro_domain/basic/idx2term.json
ADDED
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@@ -0,0 +1 @@
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|
| 1 |
+
{"0": "GOLD domain [IPR009038]", "1": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "2": "14-3-3 domain [IPR023410]", "3": "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "4": "AP complex, mu/sigma subunit [IPR022775]", "5": "Actin-depolymerising factor homology domain [IPR002108]", "6": "TGS [IPR004095]"}
|
interpro_domain/basic/plot_0.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/plot_1.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/plot_2.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/plot_3.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/plot_4.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/plot_5.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/plot_6.png
ADDED
|
Git LFS Details
|
interpro_domain/consensus.joblib
ADDED
|
@@ -0,0 +1,3 @@
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| 1 |
+
version https://git-lfs.github.com/spec/v1
|
| 2 |
+
oid sha256:fa77633020883f6ae74d2d4faf8922bd07601be59c27e38994706edef6dce8e2
|
| 3 |
+
size 150063
|
interpro_domain/df_merge.tsv
ADDED
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@@ -0,0 +1,2 @@
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| 1 |
+
term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
|
| 2 |
+
Heat shock chaperonin-binding [IPR006636] 2 6 2.090734395880063 0.0365518798644446 1.9975728155339805 4.283980582524272 0.4073375669327513 0.504919451488752 1.1374020525583366 1.1188741218715514 0.9480073173795736 0.3222446616186543 1.0 1.0 1.0 0.0147480216610697 0.0053031795330487
|
interpro_domain/metrics.json
ADDED
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@@ -0,0 +1,7 @@
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| 1 |
+
{
|
| 2 |
+
"type_of_task": "ranksum",
|
| 3 |
+
"signature_size": 2640,
|
| 4 |
+
"annotations_size": 2271,
|
| 5 |
+
"title": "Average number of proteins per term",
|
| 6 |
+
"value": 2.0409511228533685
|
| 7 |
+
}
|
interpro_domain/paths.json
ADDED
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@@ -0,0 +1 @@
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|
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|
| 1 |
+
{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C373/C373_val_log2fc"}
|
interpro_domain/result.tsv
ADDED
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@@ -0,0 +1,164 @@
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|
| 1 |
+
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
|
| 2 |
+
Reticulon [IPR003388] 0.9430955993930136 2.21666572934121 0.0266459423215135 1.0 0.4473826700873141 4 Q9NQC3,O95197,Q16799 3
|
| 3 |
+
Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.9343702579666076 2.182631060811084 0.0290629904834993 1.0 0.4473826700873141 4 O43169,Q9UMX5,O15173 3
|
| 4 |
+
Heat shock chaperonin-binding [IPR006636] 0.7983887858377025 2.090734395880063 0.0365518798644446 1.0 0.4473826700873141 6 Q9NRR5,Q9UMX0 2
|
| 5 |
+
LEM domain [IPR003887] 0.8956705352387254 2.030315066647738 0.0423245236927796 1.0 0.4473826700873141 4 Q86XL3,P42167 2
|
| 6 |
+
Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8133364597982217 1.9209816036717888 0.0547340267691209 1.0 0.4473826700873141 5 P55786,Q9UIQ6 2
|
| 7 |
+
Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8133364597982217 1.9209816036717888 0.0547340267691209 1.0 0.4473826700873141 5 P55786,Q9UIQ6 2
|
| 8 |
+
Alpha/beta hydrolase fold-1 [IPR000073] 0.8644972982594636 1.9060707168476845 0.0566410313449998 1.0 0.4473826700873141 4 P07099 1
|
| 9 |
+
GOLD domain [IPR009038] 0.7576829703944943 1.8805701874841776 0.060030410344986 1.0 0.4543473283479914 7 Q9BVK6,Q15363,P49755,Q9Y3A6,Q9Y3B3 5
|
| 10 |
+
FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.7342261559443927 1.7156088486532444 0.0862336578698306 1.0 0.4873915817486825 9 Q02790,P62942,Q9NWM8,O00170,P26885,Q96AY3 6
|
| 11 |
+
P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.761073822542101 1.698479512517789 0.0894172962467432 1.0 0.4873915817486825 5 Q9HD20 1
|
| 12 |
+
TRAM/LAG1/CLN8 homology domain [IPR006634] 0.96397421312097 1.5982707855251848 0.1099827262007657 1.0 0.5061768558038515 3 Q96CP7,Q15629 2
|
| 13 |
+
Glutathione S-transferase, N-terminal [IPR004045] 0.6864805859191847 1.5290434984639596 0.126253660814791 1.0 0.5177905359423983 8 Q9H7Z7,P78417,Q8TB36 3
|
| 14 |
+
Thiolase, N-terminal [IPR020616] 0.6899145504363189 1.3900227366213045 0.1645219732256142 1.0 0.5545730879458545 5 P22307 1
|
| 15 |
+
Thiolase, C-terminal [IPR020617] 0.6899145504363189 1.3900227366213045 0.1645219732256142 1.0 0.5545730879458545 5 P22307 1
|
| 16 |
+
ABC transporter type 1, transmembrane domain [IPR011527] 0.7230906541138435 1.3291522377688605 0.1837977490136917 1.0 0.5809173335551859 4 P08183 1
|
| 17 |
+
Aminotransferase, class I/classII [IPR004839] 0.6719263087135984 1.3114242441763166 0.1897144723687076 1.0 0.5856275400000769 5 Q6YP21,O15269 2
|
| 18 |
+
ERAP1-like C-terminal domain [IPR024571] 0.8820629503223324 1.2902414459717082 0.1969668400277557 1.0 0.59714576223777 3 P55786,Q9UIQ6 2
|
| 19 |
+
Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8596890405764069 1.2063485772334497 0.22768311464197 1.0 0.6340612316020052 3 Q9Y282,Q96RQ1 2
|
| 20 |
+
Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8596890405764069 1.2063485772334497 0.22768311464197 1.0 0.6340612316020052 3 Q9Y282,Q96RQ1 2
|
| 21 |
+
Zinc finger, CHHC-type [IPR012996] 0.8502085703450879 1.1709096873702778 0.2416350808035243 1.0 0.6517259720959665 3 P52597,P31943 2
|
| 22 |
+
Phosphoribosyltransferase domain [IPR000836] 0.5837299465318238 1.1135158971056425 0.2654869246672244 1.0 0.6804975236109105 6 P11908 1
|
| 23 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139] 0.6683311646075517 1.1037712331412408 0.2696923865386038 1.0 0.687397766362704 4 P56545,Q13363 2
|
| 24 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140] 0.6683311646075517 1.1037712331412408 0.2696923865386038 1.0 0.687397766362704 4 P56545,Q13363 2
|
| 25 |
+
Peptidase M16, C-terminal [IPR007863] 0.5736392529212867 1.038004862698625 0.2992677912120096 1.0 0.7237882362539657 7 Q10713 1
|
| 26 |
+
Peptidase M16, N-terminal [IPR011765] 0.5736392529212867 1.038004862698625 0.2992677912120096 1.0 0.7237882362539657 7 Q10713 1
|
| 27 |
+
Choline/carnitine acyltransferase domain [IPR039551] 0.9397270659590604 0.939144690375862 0.3476564617692532 1.0 0.761357593710679 2 P23786 1
|
| 28 |
+
Peptidase M3A/M3B catalytic domain [IPR001567] 0.779168628659236 0.9092531697337808 0.3632165040355004 1.0 0.7768247449491613 3 Q99797 1
|
| 29 |
+
Target SNARE coiled-coil homology domain [IPR000727] 0.5514986855981864 0.9085024584818768 0.3636128154473617 1.0 0.7768247449491613 8 O00161,Q13190,Q86Y82,Q9UNK0 4
|
| 30 |
+
Immunoglobulin-like domain [IPR007110] 0.5529017251093068 0.8876027062639148 0.374754497424169 1.0 0.7836716976521987 9 P35613 1
|
| 31 |
+
Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672] 0.9192570128885468 0.8708883130262249 0.3838151386352657 1.0 0.7909656804361964 2 Q9UHQ4 1
|
| 32 |
+
BAP29/BAP31, transmembrane domain [IPR040463] 0.9192570128885468 0.8708883130262249 0.3838151386352657 1.0 0.7909656804361964 2 Q9UHQ4 1
|
| 33 |
+
Peptidase M28 [IPR007484] 0.7671596511186966 0.8660493365317848 0.3864631067269792 1.0 0.79426037590676 3 Q7Z2K6,P02786 2
|
| 34 |
+
Glutamine amidotransferase type 2 domain [IPR017932] 0.764454028674961 0.8563715026058405 0.3917923222938184 1.0 0.8037582329984297 3 P08243 1
|
| 35 |
+
Intermediate filament head, DNA-binding domain [IPR006821] 0.7622767621949715 0.848599407721124 0.3961042366596403 1.0 0.8082759469734315 3 P08670 1
|
| 36 |
+
Metaxin, glutathione S-transferase domain [IPR033468] 0.9101592115238794 0.8409040497872572 0.4004016894825142 1.0 0.8111616742326403 2 O75431 1
|
| 37 |
+
Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9101592115238794 0.8409040497872572 0.4004016894825142 1.0 0.8111616742326403 2 O75431 1
|
| 38 |
+
3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.7467879680782479 0.7937465259658705 0.4273430087298602 1.0 0.8353524454969347 3 P40939 1
|
| 39 |
+
3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.7467879680782479 0.7937465259658705 0.4273430087298602 1.0 0.8353524454969347 3 P40939 1
|
| 40 |
+
Alpha-L-fucosidase, C-terminal [IPR031919] 0.8938589840788482 0.7877989595804026 0.4308143097408294 1.0 0.8353524454969347 2 Q9BTY2 1
|
| 41 |
+
VHS domain [IPR002014] 0.7418163601811889 0.7763145764482391 0.4375632685516972 1.0 0.8353524454969347 3 O60784 1
|
| 42 |
+
Glycosyl transferase, family 1 [IPR001296] 0.8847611827141786 0.7585367028861038 0.4481297493681118 1.0 0.8424690900786274 2 Q2TAA5 1
|
| 43 |
+
ELMO domain [IPR006816] 0.8836239575435949 0.754899303572717 0.4503094036882666 1.0 0.8447555979523496 2 Q96JJ3 1
|
| 44 |
+
Major facilitator superfamily domain [IPR020846] 0.8805913570887021 0.7452224734574553 0.4561372391333176 1.0 0.8464292572748661 2 P53985 1
|
| 45 |
+
Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610] 0.8703563305534382 0.7128181345082644 0.4759583024957121 1.0 0.8619627631321868 2 Q9NZ45 1
|
| 46 |
+
Iron-binding zinc finger, CDGSH type [IPR018967] 0.8703563305534382 0.7128181345082644 0.4759583024957121 1.0 0.8619627631321868 2 Q9NZ45 1
|
| 47 |
+
Complex 1 LYR protein domain [IPR008011] 0.867323730098548 0.7032954721163507 0.4818716318635301 1.0 0.8637654870979674 2 Q9NU23 1
|
| 48 |
+
Aldehyde dehydrogenase domain [IPR015590] 0.5032136328881364 0.6924211325373751 0.4886728984765804 1.0 0.8730529407965095 8 P51648 1
|
| 49 |
+
Band 7 domain [IPR001107] 0.4962658412097791 0.6876057475838423 0.4917010878014149 1.0 0.8764938543147671 7 P27105,O75955 2
|
| 50 |
+
BTB/POZ domain [IPR000210] 0.706863860447472 0.6566063125971029 0.5114340888556206 1.0 0.8935332600424679 3 Q9NXV2,Q08380 2
|
| 51 |
+
v-SNARE, coiled-coil homology domain [IPR042855] 0.7028683412700902 0.64328189232265 0.5200412037032716 1.0 0.8953855751403562 3 O15498 1
|
| 52 |
+
Longin domain [IPR010908] 0.7028683412700902 0.64328189232265 0.5200412037032716 1.0 0.8953855751403562 3 O15498 1
|
| 53 |
+
Zinc finger, MYND-type [IPR002893] 0.845716451857458 0.6365769797081877 0.5244004238829407 1.0 0.8960813203452377 2 Q9H7B4 1
|
| 54 |
+
Alcohol dehydrogenase, N-terminal [IPR013154] 0.694734242758427 0.6164145078949839 0.5376209805848013 1.0 0.9041058685540576 3 Q99536 1
|
| 55 |
+
Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.5023685968973928 0.5898857327943613 0.5552672598403756 1.0 0.9085100483411332 5 Q13885,Q9BUF5 2
|
| 56 |
+
Tubulin/FtsZ, GTPase domain [IPR003008] 0.5023685968973928 0.5898857327943613 0.5552672598403756 1.0 0.9085100483411332 5 Q13885,Q9BUF5 2
|
| 57 |
+
MCM, AAA-lid domain [IPR041562] 0.4646642537298897 0.5761395161709618 0.5645208834989219 1.0 0.9131731881521908 6 Q14566 1
|
| 58 |
+
MCM N-terminal domain [IPR027925] 0.4646642537298897 0.5761395161709618 0.5645208834989219 1.0 0.9131731881521908 6 Q14566 1
|
| 59 |
+
MCM OB domain [IPR033762] 0.4646642537298897 0.5761395161709618 0.5645208834989219 1.0 0.9131731881521908 6 Q14566 1
|
| 60 |
+
MCM domain [IPR001208] 0.4646642537298897 0.5761395161709618 0.5645208834989219 1.0 0.9131731881521908 6 Q14566 1
|
| 61 |
+
Rhodanese-like domain [IPR001763] 0.6803185437997721 0.569710243109724 0.5688742415329711 1.0 0.9141360710188048 3 Q99956,Q8NCN5 2
|
| 62 |
+
Glutathione S-transferase, C-terminal-like [IPR010987] 0.4895431464893832 0.5607138776387405 0.5749926051321994 1.0 0.9182898778166138 11 Q9H7Z7,P78417,Q8TB36 3
|
| 63 |
+
Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.4580681805585208 0.548289175292971 0.583493358890943 1.0 0.9231970527523856 6 P49748 1
|
| 64 |
+
GINS subunit, domain A [IPR021151] 0.6638362643669724 0.5178808645708574 0.6045413937412116 1.0 0.9339547654328516 3 Q9Y248 1
|
| 65 |
+
Proteasome activator PA28, N-terminal domain [IPR003185] 0.661623352475037 0.5110598454570344 0.6093091520568501 1.0 0.9371818009650764 3 P61289 1
|
| 66 |
+
Proteasome activator PA28, C-terminal domain [IPR003186] 0.661623352475037 0.5110598454570344 0.6093091520568501 1.0 0.9371818009650764 3 P61289 1
|
| 67 |
+
Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.5138873044852265 0.5062007299786152 0.6127157426132981 1.0 0.9378252748552982 4 Q8N8N7 1
|
| 68 |
+
Ubiquitin-associated domain [IPR015940] 0.4867622514297478 0.5038108835018269 0.614394278917028 1.0 0.9378252748552982 13 Q9NRR5,Q9UMX0 2
|
| 69 |
+
Cobalamin (vitamin B12)-binding domain [IPR006158] 0.7884761182714172 0.4713291705852137 0.6374056876144314 1.0 0.9563469259251878 2 Q99707 1
|
| 70 |
+
Intermediate filament, rod domain [IPR039008] 0.4425541073155288 0.4614126732111454 0.6445025608268744 1.0 0.9572696635957044 7 P08670 1
|
| 71 |
+
Ubiquitin system component CUE [IPR003892] 0.6446719757299983 0.4599765205830832 0.6455330736612463 1.0 0.9581041834010252 3 Q9Y679,Q86UW6 2
|
| 72 |
+
Ubiquitin-like domain [IPR000626] 0.485384068952812 0.4550508465188859 0.6490726590334914 1.0 0.9615420800163464 15 Q9NRR5,Q9UMX0 2
|
| 73 |
+
Syntaxin, N-terminal domain [IPR006011] 0.6328433232667516 0.4256334278334259 0.6703749783293 1.0 0.9673871438856632 3 Q86Y82 1
|
| 74 |
+
Thioesterase domain [IPR006683] 0.7611827141774042 0.3997420671752466 0.6893465044930116 1.0 0.9703934433905144 2 Q9NPJ3 1
|
| 75 |
+
Ion transporter-like, CBS domain [IPR044751] 0.7577710386656438 0.3911714301540361 0.6956705246497861 1.0 0.9703934433905144 2 Q8NE01 1
|
| 76 |
+
CNNM, transmembrane domain [IPR002550] 0.7577710386656438 0.3911714301540361 0.6956705246497861 1.0 0.9703934433905144 2 Q8NE01 1
|
| 77 |
+
GAT domain [IPR004152] 0.7532221379833174 0.3798813015440296 0.7040335279234489 1.0 0.971761659178762 2 O60784 1
|
| 78 |
+
SET domain [IPR001214] 0.6150721644955864 0.3762344173399201 0.7067426305885873 1.0 0.971761659178762 3 Q9H7B4 1
|
| 79 |
+
Phospholipase/carboxylesterase/thioesterase [IPR003140] 0.7486732373009884 0.368750865269828 0.7123134313600723 1.0 0.971761659178762 2 O95372 1
|
| 80 |
+
Fxr1, tudor domain [IPR041560] 0.6103463616138818 0.3635691090507168 0.7161797977464341 1.0 0.971761659178762 3 P51114 1
|
| 81 |
+
Fragile X-related 1 protein, C-terminal core [IPR022034] 0.6103463616138818 0.3635691090507168 0.7161797977464341 1.0 0.971761659178762 3 P51114 1
|
| 82 |
+
Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.6103463616138818 0.3635691090507168 0.7161797977464341 1.0 0.971761659178762 3 P51114 1
|
| 83 |
+
Agenet-like domain [IPR008395] 0.6103463616138818 0.3635691090507168 0.7161797977464341 1.0 0.971761659178762 3 P51114 1
|
| 84 |
+
Legume-like lectin [IPR005052] 0.7463987869598077 0.3632464313505064 0.71642080572349 1.0 0.971761659178762 2 P49257 1
|
| 85 |
+
FAD dependent oxidoreductase [IPR006076] 0.6099961260424942 0.362638638696672 0.7168748427659573 1.0 0.971761659178762 3 Q9H9P8 1
|
| 86 |
+
Saposin B type domain [IPR008139] 0.7399545109931731 0.347874319930795 0.7279345718824075 1.0 0.971761659178762 2 P07602 1
|
| 87 |
+
Exosome complex component, N-terminal domain [IPR025721] 0.7300985595147798 0.3250183589286073 0.7451671769695292 1.0 0.971761659178762 2 Q9Y3B2 1
|
| 88 |
+
14-3-3 domain [IPR023410] 0.3933181473044798 0.2975024527753493 0.7660829356784049 1.0 0.971761659178762 6 Q04917,P31946,P61981,P62258,P63104 5
|
| 89 |
+
EF hand associated, type-2 [IPR013567] 0.7130401819560273 0.287399812427017 0.7738062048040273 1.0 0.971761659178762 2 Q8IXI1 1
|
| 90 |
+
EF hand associated, type-1 [IPR013566] 0.7130401819560273 0.287399812427017 0.7738062048040273 1.0 0.971761659178762 2 Q8IXI1 1
|
| 91 |
+
MIRO domain [IPR020860] 0.7130401819560273 0.287399812427017 0.7738062048040273 1.0 0.971761659178762 2 Q8IXI1 1
|
| 92 |
+
DNA2/NAM7 helicase, helicase domain [IPR041677] 0.4407253581528382 0.2801863371231816 0.7793345484327701 1.0 0.971761659178762 4 P42694 1
|
| 93 |
+
Potassium channel tetramerisation-type BTB domain [IPR003131] 0.7065959059893818 0.2738495391581322 0.7842002515052413 1.0 0.971761659178762 2 Q9NXV2 1
|
| 94 |
+
CRAL-TRIO lipid binding domain [IPR001251] 0.5702796443849253 0.2649193870367621 0.7910715630761165 1.0 0.971761659178762 3 O76054 1
|
| 95 |
+
CBS domain [IPR000644] 0.3834291108848514 0.2638357385219969 0.7919064946174341 1.0 0.971761659178762 6 P54619,Q8NE01 2
|
| 96 |
+
Spermidine synthase, tetramerisation domain [IPR035246] 0.6902956785443495 0.2412478601070823 0.8093630190782208 1.0 0.971761659178762 2 P52788 1
|
| 97 |
+
Polyamine biosynthesis domain [IPR030374] 0.6902956785443495 0.2412478601070823 0.8093630190782208 1.0 0.971761659178762 2 P52788 1
|
| 98 |
+
DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.3994652474561425 0.2357557231026459 0.8136222275723155 1.0 0.971761659178762 5 P42694 1
|
| 99 |
+
Proteasome alpha-subunit, N-terminal domain [IPR000426] 0.3782757311052048 0.229634263034215 0.8183759801951349 1.0 0.971761659178762 7 P28066,P60900,P25787,P25788,P25786,O14818 6
|
| 100 |
+
MD-2-related lipid-recognition domain [IPR003172] 0.6793025018953734 0.2206448559831545 0.8253689716736556 1.0 0.971761659178762 2 P61916 1
|
| 101 |
+
AP complex, mu/sigma subunit [IPR022775] 0.3595292331055483 0.1889109622530626 0.8501626016417694 1.0 0.971761659178762 6 P53680,Q9Y2T2,Q96CW1,Q92572,P61923 5
|
| 102 |
+
ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100] 0.4022877743277074 0.1879889739719608 0.850885294583076 1.0 0.971761659178762 4 P21281 1
|
| 103 |
+
ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194] 0.4022877743277074 0.1879889739719608 0.850885294583076 1.0 0.971761659178762 4 P21281 1
|
| 104 |
+
Mu homology domain [IPR028565] 0.401833791403831 0.1870267468493191 0.8516396619914204 1.0 0.971761659178762 4 Q9Y2T2 1
|
| 105 |
+
Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152] 0.3776091081593999 0.1783326925997179 0.8584617053212318 1.0 0.971761659178762 5 P63010,Q10567,Q9UJY5,O43747 4
|
| 106 |
+
EB1, C-terminal [IPR004953] 0.6527672479150848 0.1756212535663928 0.8605915039370413 1.0 0.971761659178762 2 Q15691 1
|
| 107 |
+
PDZ domain 6 [IPR041489] 0.6489764973464738 0.1697383297518164 0.8652159286590584 1.0 0.971761659178762 2 O43464 1
|
| 108 |
+
Fumarate lyase, N-terminal [IPR022761] 0.6478392721758878 0.1680002899528181 0.8665830509718264 1.0 0.971761659178762 2 P07954 1
|
| 109 |
+
COMM domain [IPR017920] 0.6417740712661009 0.1589397995383834 0.8737163037370284 1.0 0.9727630042070554 2 Q86X83 1
|
| 110 |
+
cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.617892342683852 0.1266653001454541 0.8992053110425768 1.0 0.9739768040142994 2 P10644 1
|
| 111 |
+
Glucosamine/galactosamine-6-phosphate isomerase [IPR006148] 0.6163760424564069 0.1247973330118414 0.9006839988346436 1.0 0.9739768040142994 2 P46926 1
|
| 112 |
+
Amine oxidase [IPR002937] 0.608794541319182 0.1157766724333776 0.9078295388689056 1.0 0.9751233156373648 2 O60341 1
|
| 113 |
+
Far upstream element-binding protein, C-terminal [IPR015096] 0.6050037907505685 0.1114641178202291 0.9112483180800292 1.0 0.9774062622431778 2 Q96AE4 1
|
| 114 |
+
Rpn11/EIF3F, C-terminal [IPR024969] 0.3581067405459131 0.1088069070817399 0.9133556452897332 1.0 0.9788724258862594 4 O00303 1
|
| 115 |
+
ENTH domain [IPR013809] 0.5879454131918135 0.0936524844475645 0.9253852162256662 1.0 0.9874173277886054 2 Q14677 1
|
| 116 |
+
ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728] 0.5875663381349465 0.0932857278391916 0.9256765701725852 1.0 0.9874173277886054 2 P60842 1
|
| 117 |
+
Polyketide synthase, enoylreductase domain [IPR020843] 0.4590772462520506 0.0839737397449719 0.9330773106541884 1.0 0.9908251331713276 3 Q99536 1
|
| 118 |
+
NECAP, PHear domain [IPR012466] 0.5765731614859763 0.0831825507498097 0.93370638713438 1.0 0.9908251331713276 2 Q9NVZ3 1
|
| 119 |
+
Tyrosine-specific protein phosphatases domain [IPR000387] 0.325237191650858 0.0732072821004567 0.941641171661221 1.0 0.9957668593191594 5 Q06124,Q99956,P51452,P18031 4
|
| 120 |
+
RAD23A/RAD23B, UBA1 domain [IPR041811] 0.554586808188024 0.0659324478800531 0.9474316071057338 1.0 1.0 2 P54725 1
|
| 121 |
+
XPC-binding domain [IPR015360] 0.554586808188024 0.0659324478800531 0.9474316071057338 1.0 1.0 2 P54725 1
|
| 122 |
+
FAST kinase leucine-rich [IPR010622] 0.5485216072782437 0.0618270282670343 0.9507005792127894 1.0 1.0 2 Q969Z0 1
|
| 123 |
+
FAST kinase-like protein, subdomain 2 [IPR013579] 0.5485216072782437 0.0618270282670343 0.9507005792127894 1.0 1.0 2 Q969Z0 1
|
| 124 |
+
RAP domain [IPR013584] 0.5485216072782437 0.0618270282670343 0.9507005792127894 1.0 1.0 2 Q969Z0 1
|
| 125 |
+
ABC transporter-like, ATP-binding domain [IPR003439] 0.311504435241469 0.0594886050301006 0.9525629412729392 1.0 1.0 7 P08183 1
|
| 126 |
+
eRF1 domain 2 [IPR005141] 0.5416982562547418 0.0575256824505896 0.9541264483417649 1.0 1.0 2 Q9BRX2 1
|
| 127 |
+
eRF1 domain 3 [IPR005142] 0.5416982562547418 0.0575256824505896 0.9541264483417649 1.0 1.0 2 Q9BRX2 1
|
| 128 |
+
eRF1 domain 1/Pelota-like [IPR005140] 0.5416982562547418 0.0575256824505896 0.9541264483417649 1.0 1.0 2 Q9BRX2 1
|
| 129 |
+
JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.3083636907060029 0.0535872316513927 0.9572640295615154 1.0 1.0 7 Q92905,O00303,O15372 3
|
| 130 |
+
Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.5333586050037943 0.0527056420526594 0.957966443568232 1.0 1.0 2 O60506 1
|
| 131 |
+
Thioredoxin domain [IPR013766] 0.3950593545719406 0.0513219352713756 0.9590689893161672 1.0 1.0 24 Q9H1E5,Q9Y320 2
|
| 132 |
+
Zinc finger C2H2 AKAP95-type [IPR034736] 0.4171406901782315 0.050421791378882 0.9597862714616474 1.0 1.0 3 O43823,Q9ULX6 2
|
| 133 |
+
CTP synthase GATase domain [IPR033828] 0.5253980288097081 0.0485313447057048 0.9612927844025294 1.0 1.0 2 P17812 1
|
| 134 |
+
CTP synthase, N-terminal [IPR017456] 0.5253980288097081 0.0485313447057048 0.9612927844025294 1.0 1.0 2 P17812 1
|
| 135 |
+
Peptidase M14, carboxypeptidase A [IPR000834] 0.5200909780136472 0.0459686083164488 0.9633352703830595 1.0 1.0 2 O75976 1
|
| 136 |
+
Actin-depolymerising factor homology domain [IPR002108] 0.3077507598784142 0.0431011808257446 0.965620878012876 1.0 1.0 8 P60983,Q14019,Q9Y281,Q16643,Q12792,P60981,Q9UJU6 7
|
| 137 |
+
TGS [IPR004095] 0.2968868640850444 0.0424516500911722 0.9661386546124592 1.0 1.0 6 P55039,Q9BW92,Q9NTK5,Q9Y295,Q9NYK5 5
|
| 138 |
+
Nucleotidyl transferase domain [IPR005835] 0.3978005309063315 0.0400618032691926 0.9680438539147016 1.0 1.0 3 Q96IJ6,Q9NR50 2
|
| 139 |
+
Exportin-2, central domain [IPR013713] 0.3784603716344371 0.0323207762402311 0.9742162408153576 1.0 1.0 3 P55060,O15397 2
|
| 140 |
+
Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211] 0.4802880970432154 0.031631333563123 0.9747660553163444 1.0 1.0 2 P09960 1
|
| 141 |
+
Peptidase M41 [IPR000642] 0.4772554965883263 0.0308443993117399 0.9753936317191196 1.0 1.0 2 Q96TA2 1
|
| 142 |
+
Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.4768764215314652 0.0307486526909621 0.9754699902507622 1.0 1.0 2 Q9UBF2 1
|
| 143 |
+
Coatomer subunit gamma, C-terminal [IPR032154] 0.4768764215314652 0.0307486526909621 0.9754699902507622 1.0 1.0 2 Q9UBF2 1
|
| 144 |
+
Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.4704321455648196 0.0292068898488536 0.9766995862744816 1.0 1.0 2 Q06124 1
|
| 145 |
+
Protein-tyrosine phosphatase, catalytic [IPR003595] 0.4704321455648196 0.0292068898488536 0.9766995862744816 1.0 1.0 2 Q06124 1
|
| 146 |
+
CSN8/PSMD8/EIF3K [IPR033464] 0.3619660694565204 0.0274413226783638 0.978107739915602 1.0 1.0 3 Q99627 1
|
| 147 |
+
26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.4613343442001539 0.0272905173806859 0.9782280200872352 1.0 1.0 2 Q13098 1
|
| 148 |
+
Importin-alpha, importin-beta-binding domain [IPR002652] 0.3578540781967771 0.0264363829634082 0.9789092748745374 1.0 1.0 3 P52292 1
|
| 149 |
+
Alpha-D-phosphohexomutase, C-terminal [IPR005843] 0.4454131918119791 0.0245836738339323 0.9803870417581512 1.0 1.0 2 Q96G03 1
|
| 150 |
+
Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844] 0.4454131918119791 0.0245836738339323 0.9803870417581512 1.0 1.0 2 Q96G03 1
|
| 151 |
+
OTU domain [IPR003323] 0.4404852160727787 0.023892527825998 0.9809383345141276 1.0 1.0 2 Q01804 1
|
| 152 |
+
FAD/NAD(P)-binding domain [IPR023753] 0.2851554083283487 0.0237185229496989 0.9810771309844928 1.0 1.0 5 O95831 1
|
| 153 |
+
Arf GTPase activating protein [IPR001164] 0.4238059135708816 0.0219858323056851 0.982459256989712 1.0 1.0 2 Q96P47 1
|
| 154 |
+
BAG domain [IPR003103] 0.4203942380591314 0.0216685022317938 0.9827123894487586 1.0 1.0 2 O95816 1
|
| 155 |
+
Peptidase M20, dimerisation domain [IPR011650] 0.4135708870356275 0.0210980875733699 0.9831674104518032 1.0 1.0 2 Q96KP4 1
|
| 156 |
+
Dual specificity phosphatase, catalytic domain [IPR000340] 0.3249905195297715 0.0208023875290637 0.9834032931793106 1.0 1.0 3 Q99956,P51452 2
|
| 157 |
+
Dual specificity protein phosphatase domain [IPR020422] 0.3249905195297715 0.0208023875290637 0.9834032931793106 1.0 1.0 3 Q99956,P51452 2
|
| 158 |
+
PIN domain [IPR002716] 0.4040940106140968 0.0204334279854335 0.9836976177360082 1.0 1.0 2 Q9Y2L1 1
|
| 159 |
+
Serine-threonine protein phosphatase, N-terminal [IPR031675] 0.388551933282788 0.0196108578922782 0.9843538021541948 1.0 1.0 2 P62136 1
|
| 160 |
+
Gamma-adaptin ear (GAE) domain [IPR008153] 0.3790750568612541 0.0192410344206759 0.9846488229198688 1.0 1.0 2 Q9UJY5 1
|
| 161 |
+
PITH domain [IPR010400] 0.3616376042456363 0.0187570728301158 0.9850348987112044 1.0 1.0 2 Q9GZP4 1
|
| 162 |
+
Adenylate kinase, active site lid domain [IPR007862] 0.3309325246398721 0.018315415651799 0.985387229617786 1.0 1.0 2 P27144 1
|
| 163 |
+
S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878] 0.3297952994692887 0.0183057345680082 0.985394952710278 1.0 1.0 2 O43865 1
|
| 164 |
+
NADP-dependent oxidoreductase domain [IPR023210] 0.2673492605233269 0.0172602093850708 0.986229029181556 1.0 1.0 3 P48507,P14550 2
|
interpro_domain/selections.json
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interpro_family/advanced/idx2term.json
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{"0": "Proteasome B-type subunit [IPR023333]", "1": "Small GTPase superfamily, ARF/SAR type [IPR006689]"}
|
interpro_family/advanced/plot_0.png
ADDED
|
Git LFS Details
|
interpro_family/advanced/plot_1.png
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|
Git LFS Details
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interpro_family/basic/idx2term.json
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| 1 |
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{"0": "Proteasome B-type subunit [IPR023333]", "1": "Small GTPase superfamily, ARF/SAR type [IPR006689]", "2": "Proteasome, subunit alpha/beta [IPR001353]", "3": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "4": "Small GTPase [IPR001806]", "5": "14-3-3 protein [IPR000308]", "6": "Proteasome alpha-type subunit [IPR023332]"}
|
interpro_family/basic/plot_0.png
ADDED
|
Git LFS Details
|
interpro_family/basic/plot_1.png
ADDED
|
Git LFS Details
|
interpro_family/basic/plot_2.png
ADDED
|
Git LFS Details
|
interpro_family/basic/plot_3.png
ADDED
|
Git LFS Details
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interpro_family/basic/plot_4.png
ADDED
|
Git LFS Details
|