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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:38e09a39311487e1d1d2b7e8658da0a97cc8a71837848e2c4ec3088e7ea239f0
+size 59965

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2631,
+    "annotations_size": 52,
+    "title": "Average number of proteins per term",
+    "value": 2.25
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C375/C375_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,9 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.5899399054211478	1.20742168260948	0.2272697894158208	0.9999984952984478	0.6565571694234825	6	P49427	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.8089802130897965	1.0557186536716223	0.2910967722737947	0.999999982997155	0.7568516079118662	3	Q9HB40,Q9H3G5	2
+Peptidase S9, serine active site [IPR002471]	0.6542411563332092	0.5062723579831313	0.6126654651440144	1.0	0.8103385429509025	2	P48147	1
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.4810091744843177	0.4129494475446307	0.6796436518002313	1.0	0.8103385429509025	4	P38606,P21281	2
+Nucleoside diphosphate kinase, active site [IPR023005]	0.5500190186382694	0.2208207291736073	0.8252320224276843	1.0	0.9385389370956648	2	P15531	1
+Protein-tyrosine phosphatase, active site [IPR016130]	0.4950532724505188	0.1463029344729838	0.8836822494113366	1.0	0.9385389370956648	3	P51452,P18031	2
+Serine/threonine-protein kinase, active site [IPR008271]	0.1650604662375154	0.1012016425499225	0.9193903928482708	1.0	0.9385389370956648	31	P49841,P51812,O14976,Q8TD19,Q96KB5,P27361,P11802	7
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.2672469656134455	0.0199197790863572	0.9841073668457876	1.0	0.9841073668457876	3	Q16881	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK2G", "CASP2", "CDC34", "CDK1", "CDK12", "CDK2", "CDK4", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "YES1"], "leading_proteins": ["ATP6V1A", "ATP6V1B2", "CDC34", "CDK4", "CPVL", "DUSP3", "GAK", "GSK3B", "MAPK3", "NEK9", "NME1", "PBK", "PREP", "PTPN1", "RPS6KA3", "SCPEP1", "TXNRD1"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:415de7b290d3bf5730a99996d3e22b98025917c152619bf534bd2bfa4245c34d
+size 59647

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2631,
+    "annotations_size": 28,
+    "title": "Average number of proteins per term",
+    "value": 4.107142857142857
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C375/C375_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.3889085923787285	1.3962288455141494	0.1626455929519514	0.9930583823186196	0.5263194019445013	32	Q96AY3,P30626,O43852,P80303,Q14257,Q9NWM8,P0DP25	7
+Beta tubulin, autoregulation binding site [IPR013838]	0.6321401370906353	1.1869890930854985	0.2352319227118835	0.9994519337728098	0.5263194019445013	5	Q9BUF5,Q13885,P07437,Q13509	4
+Peptidase M16, zinc-binding site [IPR001431]	0.4072302181095097	0.3159623578975024	0.752031079634794	1.0	0.8098796242220858	5	O75439,Q10713	2
+Biotin-binding site [IPR001882]	0.2688855860512085	0.0402044076886093	0.9679301636456548	1.0	0.9679301636456548	4	P11498,P05165	2

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK2G", "CDK1", "CDK12", "CDK2", "CDK4", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAP4K5", "MAPK1", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TKT", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CALU", "FKBP10", "FKBP14", "NUCB2", "PC", "PCCA", "PMPCA", "PMPCB", "RCN2", "SRI", "TUBB", "TUBB2A", "TUBB3", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:e059e7f9168f6cb1e75e2f7ca0dfa6a7ec39c0bd352789e1d6f5d77700092fc4
+size 77183

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	7	8	2.754226755275943	0.0058830992113296	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.0010343090391069	1.5472815952013036e-06	3.5093277928655683e-08	1.1869042675635204e-09

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2631,
+    "annotations_size": 251,
+    "title": "Average number of proteins per term",
+    "value": 2.4342629482071714
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C375/C375_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,22 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.8593213877239909	2.754226755275943	0.0058830992113296	0.7725940826346998	0.1249280720553127	8	P28072,P25789,P28074,P49721,P49720,P20618,P28070	7
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.8355185178906898	1.7985592334174048	0.0720884308954237	0.9999999930152002	0.2842771626161283	4	P48735	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.9334347660707492	1.5783205480522369	0.1144919876543415	0.9999999999999444	0.3560080673169821	2	P04066	1
+Annexin repeat, conserved site [IPR018252]	0.6361253133436584	1.4184989596710371	0.1560451422018018	1.0	0.4122876915016029	6	P08133,P20073,P09525	3
+Profilin conserved site [IPR027310]	0.8843666793457592	1.3800160279112832	0.1675817099456402	1.0	0.42894126585962	2	P07737	1
+Haem oxygenase conserved site [IPR018207]	0.8771395968048695	1.3508318782277629	0.1767492938879913	1.0	0.4349418898616257	2	P30519	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.4905638310562725	1.2644790900237315	0.2060581212017829	1.0	0.4408518726892926	12	P09417,Q06136,Q6UWP2	3
+Purine phosphorylase, family 2, conserved site [IPR018099]	0.8539368581209599	1.257312328257922	0.208640561570105	1.0	0.4408518726892926	2	Q13126	1
+14-3-3 protein, conserved site [IPR023409]	0.5963948280713915	1.2369144572213602	0.2161188421830402	1.0	0.4408518726892926	6	P63104,P62258,Q04917	3
+Tubulin, conserved site [IPR017975]	0.6321401370906353	1.1869890930854985	0.2352319227118835	1.0	0.4642351770658848	5	Q9BUF5,Q13885,P07437,Q13509	4
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.5837768609799869	1.1792828677017255	0.2382855579315488	1.0	0.4642351770658848	6	P30837,P49419,P05091	3
+Ubiquitin specific protease, conserved site [IPR018200]	0.5223859735483293	1.1361825612087166	0.2558801673771298	1.0	0.4722494265563205	8	Q96K76,O94966	2
+Polyamine biosynthesis domain, conserved site [IPR030373]	0.7911753518448092	1.0073044310463264	0.3137885010818584	1.0	0.5321683362942328	2	P19623	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5077598391240176	0.837219731663701	0.4024690682710776	1.0	0.6133765534144541	6	P30837,Q02252,P51649,P05091	4
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.5721355157974825	0.7346537540927305	0.4625503917013145	1.0	0.6450008239834997	4	Q9UBQ7,P56545,Q13363	3
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.6357026959728882	0.4681448548232244	0.6396810044750048	1.0	0.7499739709837095	3	Q9Y2T2	1
+Actin, conserved site [IPR004001]	0.5488779003423395	0.2183866842958366	0.8271278395612887	1.0	0.9105661742538748	2	O96019	1
+Adenylate kinase, conserved site [IPR033690]	0.3511885651827006	0.1113077876890301	0.9113722800999772	1.0	0.9697873807330836	4	P30085	1
+Ras GTPase-activating protein, conserved site [IPR023152]	0.462179162875018	0.1021665659170296	0.9186244653876744	1.0	0.9697873807330836	3	Q13576	1
+Phosphofructokinase, conserved site [IPR015912]	0.3678139498906232	0.0349370459933164	0.9721299402032548	1.0	0.9946757538212206	3	P17858	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.3359969558599589	0.0265428611370298	0.9788243473858228	1.0	0.9946757538212206	3	Q08426,Q16836	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARHGEF7", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CETN2", "CHAF1B", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX6", "DHCR7", "DHFR", "DHRS11", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPDR1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "KDSR", "KIF11", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MPI", "MPP6", "MPST", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NEFM", "NES", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NVL", "OSBPL11", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASA1", "RCL1", "RDH13", "RDX", "RIDA", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5L1", "SPTBN1", "SRM", "STMN1", "STOM", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "TAP2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "USP10", "USP14", "USP19", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ACTL6A", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ANXA4", "ANXA6", "ANXA7", "AP3M1", "CMPK1", "CTBP1", "CTBP2", "DHRS11", "EHHADH", "FUCA1", "GRHPR", "HADH", "HMOX2", "IDH2", "IQGAP2", "KDSR", "MTAP", "PFKL", "PFN1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "QDPR", "SRM", "TUBB", "TUBB2A", "TUBB3", "TUBB6", "USP19", "USP47", "YWHAE", "YWHAH", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "1": "Importin-beta, N-terminal domain [IPR001494]", "2": "EF-hand domain [IPR002048]", "3": "Ubiquitin-like domain [IPR000626]", "4": "Small GTP-binding protein domain [IPR005225]", "5": "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "6": "Proteasome component (PCI) domain [IPR000717]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:b11699dde47387a20bd0f8ba9f4e93f07134a17eac74e5abee979168059ce5bc
+size 262906

interpro_domain/df_merge.tsv

@@ -0,0 +1,6 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500
+GOLD domain [IPR009038]	3	7	2.446471509494998	0.0144262198596516	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	0.0619434524836269	0.0065261066260236	0.0001960616495152	0.0002434795729679
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	5	9	2.262871453965156	0.0236436145594591	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	0.0017760204843955	0.0002227826640135	0.0001960616495152	1.6091572544199994e-05
+Aminopeptidase N-like , N-terminal domain [IPR045357]	2	5	2.236405076411083	0.0253252489216406	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.000647621121882	4.515786717225142e-05	0.0007018811705627	0.0052730305790767
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	2	5	2.236405076411083	0.0253252489216406	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.000647621121882	4.515786717225142e-05	0.0007018811705627	0.0052730305790767
+Gelsolin-like domain [IPR007123]	1	5	1.980585541282108	0.0476377717146401	2.436893203883495	5.684466019417476	0.1102730354515689	0.541930652597163	1.5974488332971282	0.8687964313558051	0.8868513705520608	0.3026189615587165	0.0526645480715484	0.0046590638338273	0.0274146616230463	0.0964811850177102

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2631,
+    "annotations_size": 2268,
+    "title": "Average number of proteins per term",
+    "value": 2.0374779541446206
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C375/C375_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,169 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+GOLD domain [IPR009038]	0.8330644322349787	2.446471509494998	0.0144262198596516	0.9999999999999952	0.1282746682655428	7	Q9Y3B3,Q15363,Q9BVK6	3
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.7347894760164788	2.2628714539651553	0.0236436145594591	1.0	0.1470454081470601	9	Q96AY3,P26885,Q9NWM8,Q14318,P62942	5
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8804275613305463	2.236405076411083	0.0253252489216406	1.0	0.1503603784143483	5	P55786,Q9UIQ6	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8804275613305463	2.236405076411083	0.0253252489216406	1.0	0.1503603784143483	5	P55786,Q9UIQ6	2
+Gelsolin-like domain [IPR007123]	0.8181513009808474	1.980585541282108	0.0476377717146401	1.0	0.1989732343440217	5	Q15437	1
+Importin-beta, N-terminal domain [IPR001494]	0.5997120005239681	1.8887495608425584	0.0589253942708754	1.0	0.2268977830328444	12	Q92973,P55060,Q9UIA9,Q96P70,O00410,Q8TEX9,Q9UI26,O14980,Q9HAV4,O15397	10
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.8355185178906898	1.7985592334174048	0.0720884308954237	1.0	0.2546675409202819	4	P48735	1
+Ataxin-2, C-terminal [IPR009818]	0.830858812388861	1.7798318525711885	0.0751034830757326	1.0	0.2569365799131186	4	Q9BPZ3	1
+Sec23/Sec24, trunk domain [IPR006896]	0.8292170989764271	1.773227775751001	0.0761909712758817	1.0	0.2569365799131186	4	Q15437	1
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.8292170989764271	1.773227775751001	0.0761909712758817	1.0	0.2569365799131186	4	Q15437	1
+Sec23/Sec24, helical domain [IPR006900]	0.8292170989764271	1.773227775751001	0.0761909712758817	1.0	0.2569365799131186	4	Q15437	1
+Sec23/Sec24 beta-sandwich [IPR012990]	0.8292170989764271	1.773227775751001	0.0761909712758817	1.0	0.2569365799131186	4	Q15437	1
+Sec23, C-terminal [IPR037550]	0.9771776340814	1.7545632118564358	0.079334048675776	1.0	0.2622880792954229	2	Q15437	1
+Cold-shock (CSD) domain [IPR019844]	0.808649731663103	1.6902380879451495	0.0909824143460613	1.0	0.2872799725007711	4	P67809	1
+ERAP1-like C-terminal domain [IPR024571]	0.9798325722983248	1.6892290544293351	0.0911755431205858	1.0	0.2872799725007711	3	P55786,Q9UIQ6	2
+Zinc finger, MYND-type [IPR002893]	0.94446557626474	1.6228483528327946	0.1046218264318845	1.0	0.311569054028803	2	Q9H7B4	1
+EF-hand domain [IPR002048]	0.3974754503349669	1.5920565093799173	0.1113720079004005	1.0	0.3226846362351735	36	Q96AY3,P60660,P30626,O43852,P80303,Q14257,Q9NWM8,P0DP25	8
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7822611343738073	1.583138811268233	0.1133898292185882	1.0	0.3255553977858951	4	O43169,O15173,Q9UMX5	3
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.9334347660707492	1.5783205480522369	0.1144919876543415	1.0	0.3270640769416954	2	P04066	1
+SET domain [IPR001214]	0.9426767518495648	1.5514670780289237	0.1207897910516928	1.0	0.33821141494474	3	Q9H7B4	1
+Ubiquitin-like domain [IPR000626]	0.5067752930744288	1.530827792588697	0.125811958811874	1.0	0.3464445397799919	15	P54725,P46379,Q9UMX0,Q9NRR5,Q99426	5
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.91061240015215	1.4860947317830289	0.1372540655872227	1.0	0.358743486150899	2	Q9NUQ9	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.747874863539211	1.4427709393062582	0.1490850080828301	1.0	0.3745862810985829	4	P28288,Q03519	2
+Phosphoribosyltransferase domain [IPR000836]	0.627309645357929	1.3782401159764757	0.1681291653376231	1.0	0.3988670993574574	6	P11908,Q06203,P00492	3
+Heat shock chaperonin-binding [IPR006636]	0.6197055160217076	1.3434885390449716	0.1791138346757876	1.0	0.4162194436933263	6	P54725,Q9NRR5	2
+Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]	0.544319166022158	1.3011347025002122	0.1932123512131542	1.0	0.429192568610611	9	Q93009,Q96K76,O94966	3
+Ubiquitin specific protease domain [IPR028889]	0.544319166022158	1.3011347025002122	0.1932123512131542	1.0	0.429192568610611	9	Q93009,Q96K76,O94966	3
+OTU domain [IPR003323]	0.8623050589577792	1.291001988142592	0.1967029881129989	1.0	0.4330166375587297	2	Q96FW1	1
+Cold-shock protein, DNA-binding [IPR002059]	0.6537468038227428	1.28019315155543	0.2004772138966069	1.0	0.4344246850162276	5	P67809	1
+Cold shock domain [IPR011129]	0.6537468038227428	1.28019315155543	0.2004772138966069	1.0	0.4344246850162276	5	P67809	1
+Nucleoside phosphorylase domain [IPR000845]	0.8539368581209599	1.257312328257922	0.208640561570105	1.0	0.4451522047422372	2	Q13126	1
+14-3-3 domain [IPR023410]	0.5963948280713915	1.2369144572213602	0.2161188421830402	1.0	0.451435817742011	6	P63104,P62258,Q04917	3
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.8496955859969519	1.2057337461290103	0.2279201687966616	1.0	0.4609868658544219	3	P52888,Q9BYT8	2
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.840623811335109	1.2038368897675704	0.22865262835737	1.0	0.4609868658544219	2	Q9NVE7	1
+CTP synthase GATase domain [IPR033828]	0.839863065804489	1.2007864422349437	0.2298340523222835	1.0	0.4609868658544219	2	P17812	1
+CTP synthase, N-terminal [IPR017456]	0.839863065804489	1.2007864422349437	0.2298340523222835	1.0	0.4609868658544219	2	P17812	1
+Zinc finger, CHHC-type [IPR012996]	0.8451293759512917	1.1888278846564595	0.234507402762877	1.0	0.4628918968374284	3	P55795,P31943	2
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.6321401370906353	1.1869890930854985	0.2352319227118835	1.0	0.4632833463923138	5	Q9BUF5,Q13885,P07437,Q13509	4
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.6321401370906353	1.1869890930854985	0.2352319227118835	1.0	0.4632833463923138	5	Q9BUF5,Q13885,P07437,Q13509	4
+Legume-like lectin [IPR005052]	0.8360593381513892	1.185543837670335	0.2358024927695228	1.0	0.4633601205510885	2	P49257	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8419881125391077	1.1772073611872211	0.2391127512682196	1.0	0.4656344014773289	3	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8419881125391077	1.1772073611872211	0.2391127512682196	1.0	0.4656344014773289	3	Q9Y282	1
+Aldehyde dehydrogenase domain [IPR015590]	0.5289377190973936	1.1689677210439084	0.242416636744259	1.0	0.4715273860514404	8	P30837	1
+Importin-alpha, importin-beta-binding domain [IPR002652]	0.838280060882796	1.1635010298599104	0.2446262805254111	1.0	0.4733894234058297	3	O60684,P52294	2
+Saposin B type domain [IPR008139]	0.8204640547736792	1.1232389848170825	0.2613360095557226	1.0	0.4943370055649533	2	P07602	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.8185621909471297	1.1156643689408805	0.2645658278010385	1.0	0.4975417060138933	2	P51114	1
+Small GTP-binding protein domain [IPR005225]	0.341166508574421	1.0988809503662615	0.2718199968031336	1.0	0.5048951467147398	37	P36405,P40616,P20338,P60953,P36404,P62820,Q9NR31,Q9Y6B6,P18085,P51153,Q9BW83,P11233	12
+Fxr1, tudor domain [IPR041560]	0.8188736681887312	1.0919954057964776	0.2748351205273693	1.0	0.5061199296622333	3	Q06787,P51114	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.8188736681887312	1.0919954057964776	0.2748351205273693	1.0	0.5061199296622333	3	Q06787,P51114	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.8188736681887312	1.0919954057964776	0.2748351205273693	1.0	0.5061199296622333	3	Q06787,P51114	2
+Agenet-like domain [IPR008395]	0.8188736681887312	1.0919954057964776	0.2748351205273693	1.0	0.5061199296622333	3	Q06787,P51114	2
+Peptidase M28 [IPR007484]	0.8143074581430716	1.0752355106444182	0.2822693006033163	1.0	0.5061199296622333	3	Q969V3,P02786	2
+Fibronectin type II domain [IPR000562]	0.8063902624572099	1.0673282118028085	0.2858236529149711	1.0	0.5061199296622333	2	Q9UBV2	1
+Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]	0.7976416888550794	1.0327554250143185	0.3017183686162941	1.0	0.517409044636489	2	Q9Y678	1
+Coatomer subunit gamma, C-terminal [IPR032154]	0.7976416888550794	1.0327554250143185	0.3017183686162941	1.0	0.517409044636489	2	Q9Y678	1
+Serine-threonine protein phosphatase, N-terminal [IPR031675]	0.7965005705591492	1.0282574444699628	0.3038287432255875	1.0	0.5188882452075546	2	P62140	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.4991503645337571	1.020458973756192	0.3075108370122499	1.0	0.5221447757565644	8	P21266,P28161,Q9H7Z7,P78417	4
+Polyamine biosynthesis  domain [IPR030374]	0.7911753518448092	1.0073044310463264	0.3137885010818584	1.0	0.5291244018242788	2	P19623	1
+Spermidine synthase, tetramerisation domain [IPR035246]	0.7911753518448092	1.0073044310463264	0.3137885010818584	1.0	0.5291244018242788	2	P19623	1
+FAD dependent oxidoreductase [IPR006076]	0.7937580021634567	1.000194264680144	0.3172165042637846	1.0	0.5320170567680135	3	Q8NCN5	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.7865615328060507	0.974086851165592	0.3300134176139901	1.0	0.5419771405854669	3	Q96CP7	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7797641688855095	0.962630011230044	0.3357332311542418	1.0	0.5489855575038359	2	O43390	1
+Exosome complex component, N-terminal domain [IPR025721]	0.7767211867630293	0.95077299418632	0.3417196244885989	1.0	0.5559823077954885	2	Q9Y3B2	1
+Glycosyltransferase 2-like [IPR001173]	0.7721567135793094	0.9330352542052328	0.3508017663326344	1.0	0.563709966355725	2	O60762	1
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.5064286245862244	0.9315981211618436	0.3515442544737244	1.0	0.5642621154610098	7	P25787,P25789,P25788,P28066,P60900	5
+Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]	0.7626473944465597	0.8962783091528979	0.3701041408826047	1.0	0.5778376706142155	2	Q9H1B7	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.4987855603784938	0.8961115641878393	0.3701931813943806	1.0	0.5778376706142155	7	Q92905,Q7L5N1,O00487,O00303	4
+Choline/carnitine acyltransferase domain [IPR039551]	0.7565614302015994	0.8729041726705459	0.3827153117344584	1.0	0.591768692375384	2	P50416	1
+Proteasome component (PCI) domain [IPR000717]	0.3912289462583901	0.8717487160614549	0.3833454774331919	1.0	0.5918499270377667	17	Q9BT78,P61201,Q13098,Q9UBW8,O00232,O43242,Q99627,O00231,Q9Y262,Q9UNM6	10
+EB1, C-terminal [IPR004953]	0.7546595663750492	0.8656253679618576	0.3866956394153207	1.0	0.5954808018665368	2	Q15691	1
+Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]	0.4668792037165967	0.862191137806638	0.3885823456404633	1.0	0.5963267108741171	8	P62136,P62140,P53041,Q6ZT21	4
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.5528855719479142	0.8501061137569652	0.3952660928647455	1.0	0.6010289935236024	5	P42694,Q9HCE1	2
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.7478128565994693	0.8395280440309927	0.4011730588411544	1.0	0.6061373964968869	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.7478128565994693	0.8395280440309927	0.4011730588411544	1.0	0.6061373964968869	2	Q13505	1
+Mu homology domain [IPR028565]	0.596938999829483	0.8307397616871203	0.4061206589781825	1.0	0.6095841525893567	4	Q9Y2T2	1
+Ubiquitin-associated domain [IPR015940]	0.3958469127681826	0.8162041569243644	0.4143833797136307	1.0	0.6162781937389048	13	P54725,Q9NRR5	2
+Glutamine amidotransferase [IPR017926]	0.5839611060866761	0.7801542909576622	0.4353000634266126	1.0	0.6337896856451445	4	P17812,Q9NRF8	2
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.5331117762440184	0.7687419761269717	0.4420465006063037	1.0	0.6414340776552122	5	Q9UNI6,P51452	2
+Rpn11/EIF3F, C-terminal [IPR024969]	0.5756739220056943	0.7482039180481974	0.4543371680943968	1.0	0.6521751248342355	4	O00487,O00303	2
+LEM domain [IPR003887]	0.5754187472945116	0.747224841097226	0.4549278516730279	1.0	0.652609973178006	4	Q86XL3	1
+Reticulon [IPR003388]	0.5751393922412389	0.7461533212332513	0.4555748021101569	1.0	0.6528995835309653	4	Q16799	1
+Peptidase M14, carboxypeptidase A [IPR000834]	0.7223278813236993	0.7440322186092037	0.4568569837141278	1.0	0.6528995835309653	2	P16870	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.5247702178436279	0.7349409837373039	0.4623754369966022	1.0	0.6564481087824612	5	Q9HD20	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]	0.5721355157974825	0.7346537540927305	0.4625503917013145	1.0	0.6564481087824612	4	Q9UBQ7,P56545,Q13363	3
+D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]	0.5721355157974825	0.7346537540927305	0.4625503917013145	1.0	0.6564481087824612	4	Q9UBQ7,P56545,Q13363	3
+Pyruvate carboxyltransferase [IPR000891]	0.7196652719665293	0.7342222695218817	0.4628132830437192	1.0	0.6564481087824612	2	P35914	1
+TGS [IPR004095]	0.4760103971450482	0.7002326111935784	0.483782048753332	1.0	0.6784576136877899	6	Q9NYK5	1
+Glutaredoxin [IPR002109]	0.6964058997321652	0.6592127886791853	0.5097591357850331	1.0	0.6939578151023139	3	P35754	1
+Peptidase M16, N-terminal [IPR011765]	0.4440383182001586	0.6502514525349099	0.5155298104492909	1.0	0.6954883618464627	7	Q5JRX3,O75439,Q10713	3
+Peptidase M16, C-terminal [IPR007863]	0.4440383182001586	0.6502514525349099	0.5155298104492909	1.0	0.6954883618464627	7	Q5JRX3,O75439,Q10713	3
+COMM domain [IPR017920]	0.6953214149866893	0.6462484466287226	0.518118469025096	1.0	0.6977985081644403	2	Q86X83	1
+ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]	0.6934195511601393	0.6395169734986839	0.5224866752935065	1.0	0.7001486992274987	2	P60842	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.6893359458824011	0.6358575359245638	0.5248692822931522	1.0	0.7001895152342351	3	Q06203	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.6907569418029693	0.6301301492657208	0.5286094354889843	1.0	0.7005107827946726	2	P10321	1
+Immunoglobulin C1-set [IPR003597]	0.6907569418029693	0.6301301492657208	0.5286094354889843	1.0	0.7005107827946726	2	P10321	1
+MHC class I-like antigen recognition-like [IPR011161]	0.6907569418029693	0.6301301492657208	0.5286094354889843	1.0	0.7005107827946726	2	P10321	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.6907569418029693	0.6301301492657208	0.5286094354889843	1.0	0.7005107827946726	2	P10321	1
+CAP Gly-rich domain [IPR000938]	0.6850254898062507	0.6217438070780145	0.5341103412763091	1.0	0.7034624007053827	3	Q99426	1
+Peptidase M20, dimerisation domain [IPR011650]	0.6831494864967693	0.6035578420896027	0.5461376484819591	1.0	0.7119509054788482	2	Q8IYS1	1
+MPN domain [IPR037518]	0.3982875271771232	0.5754070690580295	0.5650160243786948	1.0	0.7229195355284013	9	Q92905,Q7L5N1,O00487,O00303	4
+FAST kinase leucine-rich [IPR010622]	0.6683149486496792	0.5528651421764847	0.5803557580246737	1.0	0.7270351777311315	2	Q9NYY8	1
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.6683149486496792	0.5528651421764847	0.5803557580246737	1.0	0.7270351777311315	2	Q9NYY8	1
+RAP domain [IPR013584]	0.6683149486496792	0.5528651421764847	0.5803557580246737	1.0	0.7270351777311315	2	Q9NYY8	1
+Metallo-beta-lactamase [IPR001279]	0.6466337010270093	0.4817480824523402	0.6299849146587475	1.0	0.7586128030627974	2	Q9UKF6	1
+GHMP kinase N-terminal domain [IPR006204]	0.6356028908330194	0.4470715073792913	0.6548234306211649	1.0	0.7728669482464479	2	P53602	1
+PITH domain [IPR010400]	0.6306580448839894	0.4318829066838472	0.6658265187914609	1.0	0.777278190006345	2	O43396	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.4810091744843177	0.4129494475446307	0.6796436518002313	1.0	0.7853480394885126	4	P38606,P21281	2
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.4810091744843177	0.4129494475446307	0.6796436518002313	1.0	0.7853480394885126	4	P38606,P21281	2
+Dual specificity phosphatase, catalytic domain [IPR000340]	0.6160578386605702	0.4117379857067428	0.6805314797430708	1.0	0.7853480394885126	3	Q9UNI6,P51452	2
+Dual specificity protein phosphatase domain [IPR020422]	0.6160578386605702	0.4117379857067428	0.6805314797430708	1.0	0.7853480394885126	3	Q9UNI6,P51452	2
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6184861163940694	0.3954863548169144	0.6924839898784372	1.0	0.7900169461993438	2	Q92945	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.6094464815223819	0.3934634733990413	0.6939771969650257	1.0	0.7909247651842605	3	Q32P28	1
+Exportin-2, central domain [IPR013713]	0.6080669710806599	0.3896976262375388	0.696760152010631	1.0	0.7917094312425407	3	P55060,O15397	2
+Exportin-1/Importin-beta-like [IPR013598]	0.6139216432103494	0.3822153123959912	0.7023016648838445	1.0	0.7957735999885643	2	O14980	1
+VHS domain [IPR002014]	0.5991496494906617	0.3657597512807609	0.7145443556596978	1.0	0.8006861704104081	3	Q9UJY5	1
+BTB/POZ domain [IPR000210]	0.5962709284626991	0.3581850298833817	0.7202048494789881	1.0	0.8066294314164666	3	Q08380,Q96CX2	2
+RNA-binding domain, S1 [IPR022967]	0.3687133897505895	0.3557489669851118	0.7220285704115232	1.0	0.8080079574767101	7	Q9Y3B2,Q14562,P62487	3
+GINS subunit, domain A [IPR021151]	0.5943683409436732	0.3532206528329354	0.7239230258162608	1.0	0.8080079574767101	3	Q9BRX5,Q9BRT9	2
+Zinc finger, FYVE-related [IPR017455]	0.4574509067094549	0.3416914570349941	0.7325831018784335	1.0	0.8123715477344137	4	Q96T51,O14964	2
+FYVE zinc finger [IPR000306]	0.4574509067094549	0.3416914570349941	0.7325831018784335	1.0	0.8123715477344137	4	Q96T51,O14964	2
+ENTH  domain [IPR013809]	0.5990871053632594	0.3405837894335829	0.733416934748574	1.0	0.8123715477344137	2	Q13492	1
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.5960441232407794	0.332337353899807	0.7396345369046167	1.0	0.8172046590711933	2	Q96CX2	1
+Ricin B, lectin domain [IPR000772]	0.5945226321795394	0.3282526456321394	0.7427206455055786	1.0	0.8193046809370877	2	Q10472	1
+Endonuclease/exonuclease/phosphatase [IPR005135]	0.5742009132419983	0.3027219751972462	0.7621017493330136	1.0	0.8386447197900412	3	Q6L8Q7,P27695	2
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.3119493449000303	0.2996706252652692	0.7644284070518221	1.0	0.8407971033916259	11	P21266,P28161,Q9H7Z7,P78417	4
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.5770254849752794	0.2831776450188303	0.7770406639822918	1.0	0.8526019477077106	2	P49591	1
+Peroxiredoxin, C-terminal [IPR019479]	0.431667925456638	0.2712796496609955	0.7861759570340043	1.0	0.8609594739512901	4	P30048,P30041	2
+Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]	0.431667925456638	0.2712796496609955	0.7861759570340043	1.0	0.8609594739512901	4	P30048,P30041	2
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.5686572841384594	0.2628957372077197	0.792630941998056	1.0	0.86552093233105	2	O15460	1
+Nucleoside diphosphate kinase-like domain [IPR034907]	0.5500190186382694	0.2208207291736073	0.8252320224276843	1.0	0.8946588082533404	2	P15531	1
+Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]	0.3380787120787101	0.2176762405940746	0.8276813770471132	1.0	0.8956837645199394	6	P62136,P62140,P53041	3
+eRF1 domain 2 [IPR005141]	0.5484975275770294	0.2175790234274297	0.8277571298208963	1.0	0.8956837645199394	2	Q9BRX2	1
+eRF1 domain 3 [IPR005142]	0.5484975275770294	0.2175790234274297	0.8277571298208963	1.0	0.8956837645199394	2	Q9BRX2	1
+eRF1 domain 1/Pelota-like [IPR005140]	0.5484975275770294	0.2175790234274297	0.8277571298208963	1.0	0.8956837645199394	2	Q9BRX2	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.3625879606387403	0.2006300485095874	0.8409878604657883	1.0	0.9065401461674945	5	Q32P28	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.3625879606387403	0.2006300485095874	0.8409878604657883	1.0	0.9065401461674945	5	Q32P28	1
+Glutathione S-transferase, C-terminal [IPR004046]	0.291250299873389	0.1903979596230299	0.8489972964148556	1.0	0.9131983183089548	9	P21266,P28161,P78417	3
+Ras GTPase-activating domain [IPR001936]	0.3883924384129468	0.1734309513235099	0.8623126980782694	1.0	0.9235424950945222	4	Q13576,P20936	2
+Lsm14-like, N-terminal [IPR025609]	0.5245340433624994	0.1704535774665613	0.8646534398455299	1.0	0.9241442043212356	2	Q9BX40	1
+YjeF N-terminal domain [IPR004443]	0.5245340433624994	0.1704535774665613	0.8646534398455299	1.0	0.9241442043212356	2	Q8NCW5	1
+DFDF domain [IPR025762]	0.5245340433624994	0.1704535774665613	0.8646534398455299	1.0	0.9241442043212356	2	Q9BX40	1
+FDF domain [IPR019050]	0.5245340433624994	0.1704535774665613	0.8646534398455299	1.0	0.9241442043212356	2	Q9BX40	1
+Biotin carboxylase-like, N-terminal domain [IPR005481]	0.3392457867153456	0.1531455139013125	0.8782835242821119	1.0	0.9351864005032064	5	P05165,O00763	2
+Biotin carboxylation domain [IPR011764]	0.3392457867153456	0.1531455139013125	0.8782835242821119	1.0	0.9351864005032064	5	P05165,O00763	2
+Biotin carboxylase, C-terminal [IPR005482]	0.3392457867153456	0.1531455139013125	0.8782835242821119	1.0	0.9351864005032064	5	P05165,O00763	2
+Target SNARE coiled-coil homology domain [IPR000727]	0.2773540045507243	0.150327473562531	0.8805062585058856	1.0	0.9365339678639424	8	Q86Y82	1
+ATP-grasp fold [IPR011761]	0.2686804584595532	0.1407410744665249	0.88807449529881	1.0	0.9420158539311332	9	P05165,O00763,Q13572	3
+TIP49, P-loop domain [IPR010339]	0.5047546595663792	0.1371748958311763	0.8908925535351238	1.0	0.9428578214734769	2	Q9Y265	1
+RuvB-like, AAA-lid domain [IPR041048]	0.5047546595663792	0.1371748958311763	0.8908925535351238	1.0	0.9428578214734769	2	Q9Y265	1
+AGC-kinase, C-terminal [IPR000961]	0.2976251715869111	0.132873774072565	0.8942932082213182	1.0	0.9451337354361368	6	P51812,Q16512	2
+Protein kinase, C-terminal [IPR017892]	0.3266073479753609	0.1312596784029704	0.8955698877300562	1.0	0.946042154341764	5	P51812,Q16512	2
+S1 domain [IPR003029]	0.2935246071799164	0.1260167490125061	0.8997186664727179	1.0	0.949982279124825	6	Q14562,P62487	2
+Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]	0.3229246001523189	0.1253853982118197	0.9002184474230799	1.0	0.9500676774106772	5	Q9UJY5,P63010,Q10567,O94973	4
+Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]	0.2775713896934773	0.1023140636782389	0.91850739268843	1.0	0.9650905153502174	6	P05165,O00763	2
+Cyclin, C-terminal domain [IPR004367]	0.4788893115252995	0.1012183561489363	0.9193771254520235	1.0	0.9650905153502174	2	O95067	1
+Cyclin, N-terminal [IPR006671]	0.4788893115252995	0.1012183561489363	0.9193771254520235	1.0	0.9650905153502174	2	O95067	1
+Cyclin-like [IPR013763]	0.4788893115252995	0.1012183561489363	0.9193771254520235	1.0	0.9650905153502174	2	O95067	1
+LSM domain, eukaryotic/archaea-type [IPR001163]	0.2130852958320271	0.065332352972331	0.9479093834140226	1.0	0.981670539535618	8	P62312,P62318	2
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.2999619337647447	0.0577486113528348	0.9539488720158662	1.0	0.984050295420484	4	P48147,Q4J6C6,P13798	3
+Acyl transferase [IPR014043]	0.4035755039939195	0.0394897400283736	0.9684999334089792	1.0	0.9950727835932978	2	P49327	1
+Phosphofructokinase domain [IPR000023]	0.3678139498906232	0.0349370459933164	0.9721299402032548	1.0	0.9950727835932978	3	P17858	1
+CRAL-TRIO lipid binding domain [IPR001251]	0.366874121241076	0.0346142624992415	0.9723873284857172	1.0	0.9950727835932978	3	Q8NHP6	1
+Pentacotripeptide-repeat region of PRORP [IPR033443]	0.3758082921262884	0.0290843762980593	0.97679729643545	1.0	0.9950727835932978	2	O75127	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.3359969558599589	0.0265428611370298	0.9788243473858228	1.0	0.9950727835932978	3	Q08426,Q16836	2
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.3359969558599589	0.0265428611370298	0.9788243473858228	1.0	0.9950727835932978	3	Q08426,Q16836	2
+Plectin/S10, N-terminal [IPR005326]	0.3583111449220286	0.024798165948181	0.9802159539711648	1.0	0.9950727835932978	2	P46783	1
+Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]	0.2672469656134455	0.0199197790863572	0.9841073668457876	1.0	0.99640870893136	3	Q16881	1
+PIN domain [IPR002716]	0.3001141118295979	0.018293745495857	0.9854045170042638	1.0	0.996478841420671	2	Q9Y2L1	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Proteasome B-type subunit [IPR023333]", "2": "Small GTPase superfamily, ARF/SAR type [IPR006689]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Proteasome B-type subunit [IPR023333]", "2": "Small GTPase superfamily, ARF/SAR type [IPR006689]", "3": "Small GTPase [IPR001806]", "4": "Proteasome alpha-type subunit [IPR023332]", "5": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "6": "Glutathione Transferase family [IPR040079]"}