diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b191c10b0de9a1f26d3531ed3acbe5d675f16a52 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fef5b1c0e71142a87711bb8370ae6a39990f6b66e3708b8b96475ef210ddd83d +size 91927 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b662587aebaa12f953c479ecad65235d8684c935 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 55, + "title": "Average number of proteins per term", + "value": 2.727272727272727 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..be6c5f9b0d5eaf31bb2ae9ed55fd8f68d6ae2696 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6041e86bdc8dce170bfab719b05b852407d2573a --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histidine acid phosphatase active site [IPR033379] 0.8510078878177114 3.138337169778455 0.0016990930773985 0.0892889395872088 0.0040630486633444 2 Q9NPH0 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.6142368755813516 1.7800236711847055 0.0750720868578469 0.9863247984671372 0.0938401085723086 3 Q9HB40 1 +Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.4826175869120763 1.1379915743286542 0.2551240006235162 0.9999999078237658 0.2698426929671806 2 P18669 1 +Glycosyl hydrolases family 31, active site [IPR030458] 0.3494011101373001 0.36343745998345 0.7162781230227724 1.0 0.7295425327083793 2 P10253 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e4cdbff887201b8f2737e490dfb01e8308b0f708 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP7", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR2", "MTMR6", "MYLK", "NEK9", "NME1", "NME3", "NME4", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TXNRD2", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UMPS", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACP6", "GAA", "PGAM1", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/advanced/plot_0.png b/interpro_binding_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a5d38e128fed60a20fedd109a6dabac131b257a6 --- /dev/null +++ b/interpro_binding_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c96312434e93a4d7b6729291d32fb05a418c93a97a29a5add9a33aab4297931c +size 189549 diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..10e8eeba27932c124b42dde09eed12d360760c29 --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Beta tubulin, autoregulation binding site [IPR013838]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c35eae2109577d8e197b9b2c9d2b20b744e28b61 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c717d415b9f09739542ddce2944ce9f00da6932694fa718c0b0bd56b7a9c0c09 +size 138564 diff --git a/interpro_binding_site/basic/plot_1.png b/interpro_binding_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..744a2025c0a0a07208307368c98336380ba7b327 --- /dev/null +++ b/interpro_binding_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2bebaa75273d79088b4e4423e92d40de7b25bed4c33e20c89e42ebbc850dad29 +size 142265 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a977e96de24b2882bb9dd8e0cf27f7d6e317bbb5 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c859316bb1aac6006dc899991801a05b7e1aaf132a5314fe62f4c577a8e1677a +size 84231 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dc2866ae2828694bba2c6bf96e2c1be811203f75 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EF-Hand 1, calcium-binding site [IPR018247] 9 37 2.303341370907963 0.0212596436626011 10.019417475728156 36.70631067961165 0.9532938980945532 0.3894555773109194 3.76037227687173 3.057484685571999 1.1082350706804749 0.3408841825650379 0.002881560367305 0.0551599902794207 0.175896893635733 0.0121231126733016 0.0047064147832106 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..849f41a87f5a615c843d64afe3fe8f948fabba17 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 32, + "title": "Average number of proteins per term", + "value": 4.75 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d939de16be2fde06d85c7c704ac6fb720058142a --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..136b3845a420283fa814ca39ac59943ff01e8944 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.5002622910385289 2.303341370907963 0.0212596436626011 0.4972409816711394 0.0358057156422755 37 O95202,Q9NWM8,Q9Y680,P80303,Q02818,Q14257,Q9BRK5,P41208,O95302 9 +Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.5965527315220656 1.8042671512855937 0.071189436734028 0.9058828711136304 0.0876177682880344 2 O15270 1 +Peptidase M16, zinc-binding site [IPR001431] 0.5120303516340137 1.01578848995829 0.3097301182511716 0.9999929432361986 0.34177116496681 5 P22695 1 +Beta tubulin, autoregulation binding site [IPR013838] 0.4562737642585474 0.641200452909962 0.5213924554181832 0.9999999999425428 0.538211566883286 6 Q13885,Q9BVA1,Q9BUF5,P07437,P04350 5 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..eb398a821cc930593511ff0dd3a067ffb40483eb --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYLK", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PPM1L", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CETN2", "FKBP14", "FKBP7", "FKBP9", "LETM1", "NUCB1", "NUCB2", "RCN2", "SDF4", "SPTLC2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..45bcdc760da5f913f01618565450e47bc8bd2f01 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Intermediate filament protein, conserved site [IPR018039]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0733ed8016479ebea4c8057cd3aef7297930f77f --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5e435b5678f4edd1b5454ba6c1dcfa090af923008f3e8bce8bd4edd6ad0b15e9 +size 190380 diff --git a/interpro_conserved_site/advanced/plot_1.png b/interpro_conserved_site/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..11b3b1864d01d6d54c7e89072c387e4aa32c7b81 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7011f6107357d6d2f31da261fdea441c334866ba5ba6c1233b2bf21c2c0e835d +size 189501 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..42c6a85c0c6e1f6158a7e138a777142ee368b4bb --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "14-3-3 protein, conserved site [IPR023409]", "3": "ABC transporter-like, conserved site [IPR017871]", "4": "Mini-chromosome maintenance, conserved site [IPR018525]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png 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sha256:2a2e0dd5d91d0a143b0710b1f3b74e3319173ce91c86f8632c73bcfdf41178f6 +size 147577 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7c8237725d53aa54683d35b2fd7aff218cbdf8fb --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6e65435cd8623ac4010b3de75eb1d5c6742f111fe76ec59998728c6e2b631781 +size 146257 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..810f2381e6fd96551f4037ea323aeee77bbfd871 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Syntaxin/epimorphin, conserved site [IPR006012] 5 8 2.384259113667661 0.0171135478634201 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 0.0001777475819892 1.0 0.0066572828402184 0.003355333516566 1.6279070379868977e-05 +Intermediate filament protein, conserved site [IPR018039] 7 8 2.154265075425477 0.0312193900764903 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.045449956495333 1.0 1.0 1.0 0.0539281835546241 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0ad5ec97b858914c189a56a17516f8594e371c16 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 282, + "title": "Average number of proteins per term", + "value": 2.765957446808511 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8d594601e3cb40672e48ef6ee9b8a8f1b2e4cfe2 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c40f978ede5f77aacdf5bf4b59ab404cd29031b7 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,28 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase conserved site [IPR018207] 0.9833479404031552 3.75262124839233 0.0001749951460705 0.0481548829311681 0.0036218495084395 2 P09601 1 +Tetraspanin, conserved site [IPR018503] 0.9421390999415544 3.4205741737287134 0.0006248909251966 0.1616120371077058 0.0049136824808923 3 O60637,O43657 2 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.9103125912941888 3.419536738677791 0.000627278614582 0.1621767109457982 0.0049136824808923 2 P13473 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.7626908463795297 2.4325937152653525 0.0149911115421494 0.9858706510357406 0.0330272926162981 4 P55899 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.7759110930713218 2.384259113667661 0.0171135478634201 0.9923096803769376 0.0358794748009803 8 P56962,O15400,O60499,Q13190,Q9P2W9 5 +Sterol reductase, conserved site [IPR018083] 0.6951579449364684 2.216514826325583 0.0266562636220286 0.999509002536762 0.0497818963007422 3 Q14739 1 +3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.6634531113058757 2.1765560743709114 0.0295137055647496 0.9997857047062814 0.0526988352935767 2 Q16836 1 +Intermediate filament protein, conserved site [IPR018039] 0.7301726660813678 2.154265075425477 0.0312193900764903 0.999869511129125 0.0550241750098142 8 P07196,P48681,Q03252,P07197,Q16352,P08670,P02545 7 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.6412503651767503 2.0547449691887127 0.0399036440079563 0.9999897013660984 0.0673822012589442 2 P04066 1 +Polyprenyl synthetase, conserved site [IPR033749] 0.631609699094368 2.0013107514960176 0.0453589118150061 0.999997935025984 0.0735127191484582 2 Q5T2R2 1 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.642022209234363 1.9323209247104824 0.0533199073013195 0.9999998053228468 0.0818073869752236 3 Q99536,Q8N4Q0 2 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.5970192869666777 1.68442374078432 0.0920998058486932 0.999999999998532 0.1219349542222136 3 P26583,O15347 2 +Thioredoxin, conserved site [IPR017937] 0.5307353899094898 1.157162109095635 0.247206135224592 1.0 0.2857054513661268 11 Q9H1E5,Q9H3N1 2 +AMP-binding, conserved site [IPR020845] 0.5345737265795973 1.082638749622151 0.2789688006405559 1.0 0.3195127607097993 7 Q9UKU0,O14975 2 +Clathrin adaptor complex, small chain [IPR000804] 0.4989769073370408 1.0192793881004796 0.3080703465604202 1.0 0.3461402907571561 4 P61923,P53680,Q92572 3 +Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.4627519719544249 1.0192392273800228 0.3080894077306602 1.0 0.3461402907571561 2 P29692 1 +Ribosomal protein S9, conserved site [IPR020574] 0.4513584574934337 0.9511140108649097 0.341546503057645 1.0 0.3806961022223553 2 P82933 1 +Ribosomal protein L24/L26, conserved site [IPR005825] 0.4478527607362008 0.9301684738206346 0.3522838621345432 1.0 0.3911183036296897 2 Q96A35 1 +14-3-3 protein, conserved site [IPR023409] 0.487569464755766 0.8084326660839162 0.4188415534583285 1.0 0.4595848952344304 6 P31946,Q04917,P27348,P63104,P62258 5 +Sulfatase, conserved site [IPR024607] 0.4198071866783621 0.7633573217173788 0.4452503250919846 1.0 0.4847899292507322 2 P15586 1 +EGF-like calcium-binding, conserved site [IPR018097] 0.4095822378031104 0.7031196193974515 0.4819812064027093 1.0 0.5227642315598617 2 Q07954 1 +Guanylate kinase, conserved site [IPR020590] 0.4342105263157804 0.5902756597628156 0.5550058549549757 1.0 0.5888530753950992 5 O14936,Q5T2T1,Q9NZW5,Q00013 4 +ABC transporter-like, conserved site [IPR017871] 0.414286575754283 0.5017122225647256 0.6158699655759938 1.0 0.6456331981131237 12 P28288,P08183,Q03519,Q9NUQ8,Q03518,O75027,P33527 7 +Mini-chromosome maintenance, conserved site [IPR018525] 0.4021643755483941 0.3646941475005804 0.7153397277882134 1.0 0.7371913528920504 6 P33991,P33993,Q14566,P49736,P33992 5 +Glycosyl hydrolases family 31, conserved site [IPR030459] 0.3494011101373001 0.36343745998345 0.7162781230227724 1.0 0.7371913528920504 2 P10253 1 +Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.3579777907656378 0.3325775328675144 0.7394532050118936 1.0 0.7582756502303781 3 Q16539,P27361 2 +Cyclic nucleotide-binding, conserved site [IPR018488] 0.3026584867075583 0.1343903895973927 0.8930938806884834 1.0 0.9026970406958864 2 P10644 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..aa16036465aef40f1444ed9660c9de00578dc834 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3'5'-cyclic nucleotide phosphodiesterase, conserved site [IPR023174]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Connexin, conserved site [IPR017990]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ARSA", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD81", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPN1", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK2", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GJC1", "GLA", "GLB1", "GLO1", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLA-F", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "ISCA2", "ITGA6", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDE8A", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RING1", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE1", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCF3", "ACSL6", "AP2S1", "AP3S1", "CASK", "COPZ1", "EEF1D", "FCGRT", "FUCA1", "GAA", "GNS", "HADH", "HMGB2", "HMGB3", "HMOX1", "INA", "LAMP2", "LBR", "LMNA", "LMNB2", "LRP1", "MAPK14", "MAPK3", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MPP1", "MPP6", "MPP7", "MRPL24", "MRPS9", "NEFL", "NEFM", "NES", "PDSS1", "PRKAR1A", "SLC27A2", "STX10", "STX17", "STX18", "STX5", "STX7", "TAP1", "TAP2", "TMX1", "TMX4", "TSPAN3", "TSPAN6", "VAT1", "VIM", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 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0000000000000000000000000000000000000000..6e6c1f46fc5ebab9a68e1b74bf40a2000666fefa --- /dev/null +++ b/interpro_domain/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-hand domain [IPR002048]", "1": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "2": "GOLD domain [IPR009038]", "3": "Target SNARE coiled-coil homology domain [IPR000727]", "4": "Band 7 domain [IPR001107]", "5": "Intermediate filament, rod domain [IPR039008]", "6": "Phospholipid/glycerol acyltransferase [IPR002123]", "7": "Immunoglobulin-like domain [IPR007110]", "8": "Thioredoxin domain [IPR013766]", "9": "ABC transporter type 1, transmembrane domain [IPR011527]", "10": "Small GTP-binding protein domain [IPR005225]", "11": "14-3-3 domain [IPR023410]", "12": "Guanylate kinase-like domain [IPR008144]", "13": "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "14": "ABC transporter-like, ATP-binding domain [IPR003439]", "15": "MCM domain [IPR001208]", "16": "MCM N-terminal domain [IPR027925]", "17": 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@@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6acf698693cb6a275eb215f8a21600440c16556f94845238be6ea2d46bcb7911 +size 141302 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e22caf6f502653ed57a43a9a528f8e435f6283ef --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1b3a036ab77c55b74dd095a033aa1c465a8f337174b2b47264efde5cb65e99f1 +size 823758 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5aeda62958e253b5617c523cb6621cb2fc06cffc --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,16 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EF-hand domain [IPR002048] 15 45 2.5997022591081373 0.0093304675895993 12.385922330097088 43.512135922330096 1.0171858714399242 0.3947118087831401 4.608360476919044 4.087317384177653 1.201458704248258 0.3652478399429377 0.0005545595591977 0.0832266786690803 0.2497932687322087 0.0106685370568607 0.0003176274883727 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 5 7 2.4645866369302003 0.0137171397286983 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.015895687074825 1.0 1.0 1.0 0.0034992238505004 +GOLD domain [IPR009038] 5 7 2.4247411737170457 0.0153193042557027 2.8762135922330097 6.247572815533981 0.4192390492462461 0.3068843884052658 1.4199402534298398 0.930533270242389 1.3963570929114475 0.294203492723015 0.0021455018963906 1.0 1.0 0.0382400085743442 0.0027630263410089 +Immunoglobulin C1-set [IPR003597] 2 5 2.3187019058846614 0.0204112051210705 1.5364077669902914 3.2645631067961167 0.6739064474228705 0.388919959347808 0.9507966556146606 0.908645932409072 1.1616974926444357 0.3094128568625329 0.2119278063992609 1.0 1.0 1.0 0.0618109910728358 +MHC class I-like antigen recognition-like [IPR011161] 2 5 2.3187019058846614 0.0204112051210705 1.6286407766990292 3.3519417475728157 0.7088257141352072 0.3792248400111384 0.978137271268229 0.8617667089672962 1.1217132539816763 0.2987888107271844 0.1302665862694917 1.0 1.0 1.0 0.0277461310389573 +Target SNARE coiled-coil homology domain [IPR000727] 8 13 2.3141029097515795 0.0206620778523958 3.5024271844660193 8.266990291262136 0.5942034778060385 0.4012381903331891 1.9023475359698396 2.183694577914796 1.0582363712887182 0.3038263160802639 0.0007104899027746 1.0 0.2147385524083838 0.1219531221716571 1.4175664763662648e-06 +Band 7 domain [IPR001107] 6 8 2.2883871227948505 0.0221149868835572 3.825242718446602 7.354368932038835 0.2848798017769268 0.3662852929750465 1.8717479731706237 0.7075565364256523 1.25010454777189 0.3076860385713043 0.0597114340227566 1.0 1.0 0.1981219124770219 0.0076703518288617 +LEM domain [IPR003887] 3 6 2.26306466927728 0.023631703091814 2.237864077669903 5.759708737864078 0.8787481060627674 0.3228260833428172 1.2758866328838632 0.4653299410110203 1.033781091163317 0.2887768895441466 5.804491071906608e-05 1.0 1.0 0.0082211090226218 7.614857799780336e-05 +Intermediate filament, rod domain [IPR039008] 7 8 2.154265075425477 0.0312193900764903 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.0751763183380364 1.0 1.0 1.0 0.088385561156941 +Glycosyltransferase 2-like [IPR001173] 3 5 2.115200884769455 0.0344128295780155 1.6092233009708738 4.266990291262136 0.4045535360652099 0.4585856527298224 1.1638621588890832 0.9407586640490804 1.0013260543440905 0.3085921397751335 0.1459993121590467 1.0 1.0 0.0498779046475234 0.1630814235328921 +Dynamin, N-terminal [IPR045063] 2 7 2.089083998411905 0.0367001625116818 3.0970873786407767 6.975728155339806 0.7379849963606689 0.4199536592827374 1.7349327124234004 0.8151438040285356 0.9001171760244049 0.3234417573977254 0.0859747520273939 1.0 1.0 0.2365379696877526 0.0140126286640228 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 2 7 2.089083998411905 0.0367001625116818 3.0970873786407767 6.975728155339806 0.7379849963606689 0.4199536592827374 1.7349327124234004 0.8151438040285356 0.9001171760244049 0.3234417573977254 0.0859747520273939 1.0 1.0 0.2365379696877526 0.0140126286640228 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 2 7 2.055408819997787 0.039839534311433 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0149736639257102 0.0561990347849709 0.0001778916397324 0.00262770885776 0.018020673376298 +Phospholipid/glycerol acyltransferase [IPR002123] 5 9 2.036792046357548 0.0416708856931933 2.4611650485436893 6.109223300970874 0.4541526786138767 0.3733328307275969 1.647577392422315 1.6678607828333205 1.200305691546449 0.3080828121567173 0.033335161975655 1.0 1.0 1.0 0.0397387250697101 +Immunoglobulin-like domain [IPR007110] 6 18 1.9712573494413492 0.0486944471456021 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 0.5858502970842022 1.0 1.0 0.9383741002437572 0.3091891760919288 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..defe0596cbe971e19b369cabc6e8148ea52dd6ec --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 2702, + "title": "Average number of proteins per term", + "value": 2.215025906735751 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6ef41c600a8540921ef460fd5e426316f84fa833 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5c23612bf100e3a787b0af9ff6382a601eda44fd --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,202 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Prenylcysteine lyase [IPR010795] 0.9699094361671072 3.692372056306471 0.0002221721186133 0.4513945468130172 0.0025604671629454 2 Q8NBM8 1 +Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610] 0.927841075080343 3.5007624425132664 0.0004639291914201 0.7145897161021776 0.0032729417107498 2 Q9NZ45 1 +Iron-binding zinc finger, CDGSH type [IPR018967] 0.927841075080343 3.5007624425132664 0.0004639291914201 0.7145897161021776 0.0032729417107498 2 Q9NZ45 1 +Choline/carnitine acyltransferase domain [IPR039551] 0.9173239848086476 3.4521273432357096 0.0005561851669568 0.7775894758938202 0.0035527478040602 2 P50416 1 +Fatty acid hydroxylase [IPR006694] 0.9024247735904196 3.382710595731726 0.0007177422413984 0.8563012008259012 0.0039529562883432 2 Q15800 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.9137931034482806 3.291351155977282 0.0009970736529356 0.9324871283561352 0.0048023048310733 3 Q13505,O75431 2 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9137931034482806 3.291351155977282 0.0009970736529356 0.9324871283561352 0.0048023048310733 3 Q13505,O75431 2 +Peptidase S54, rhomboid domain [IPR022764] 0.8825591586327798 3.289192786723328 0.0010047517671532 0.9338747136834056 0.0048050252652176 2 Q6NTF9 1 +Glycosyl transferase, family 1 [IPR001296] 0.8778848962898103 3.2670259798876873 0.0010868370603209 0.9470406539476988 0.0049025604958051 2 Q9BT22 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8661992404323726 3.2113335827934266 0.0013212046958392 0.971907578835716 0.0054394628393809 2 Q9NVI7 1 +Syntaxin 6, N-terminal [IPR015260] 0.8583114227286099 3.17351645063429 0.0015060436688307 0.982963503235195 0.0059560190779935 2 O60499 1 +Fzo/mitofusin HR2 domain [IPR006884] 0.8565585743499884 3.165087813476252 0.0015503615303154 0.9848889272160068 0.0060976373433947 2 Q8IWA4 1 +FAD-binding domain, PCMH-type [IPR016166] 0.8545135845749399 3.155242933873865 0.0016036451577177 0.9869181207761596 0.0062525962715054 2 Q15392 1 +FAD linked oxidase, N-terminal [IPR006094] 0.8545135845749399 3.155242933873865 0.0016036451577177 0.9869181207761596 0.0062525962715054 2 Q15392 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8831092928112271 3.1490418076328575 0.0016380675884668 0.9880817886038123 0.0063501558451039 3 Q96RQ1,Q9Y282 2 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8831092928112271 3.1490418076328575 0.0016380675884668 0.9880817886038123 0.0063501558451039 3 Q96RQ1,Q9Y282 2 +ELMO domain [IPR006816] 0.8527607361963213 3.14679461100408 0.0016507087056722 0.9884826448376216 0.0063808511054743 2 Q96JJ3 1 +Tim44-like domain [IPR007379] 0.8521764534034495 3.1439764780981396 0.0016666883603895 0.98897013847707 0.0064334170711035 2 O43615 1 +Reticulon [IPR003388] 0.9109637867350135 3.1382146421479855 0.0016998035374076 0.9899157156789036 0.0064597315866039 4 Q9NQC3,O75298 2 +DNA/RNA non-specific endonuclease [IPR001604] 0.8442886356996839 3.1058321352453113 0.001897443974359 0.9940938658218528 0.0069287838247655 2 O94919 1 +Extracellular Endonuclease, subunit A [IPR020821] 0.8442886356996839 3.1058321352453113 0.001897443974359 0.9940938658218528 0.0069287838247655 2 O94919 1 +Diacylglycerol kinase, catalytic domain [IPR001206] 0.82617586912066 3.01753187439707 0.0025484223898042 0.9989867844001712 0.0082762467515036 2 Q53H12 1 +BAP29/BAP31, transmembrane domain [IPR040463] 0.8188723342097602 2.981643300562741 0.0028670583233938 0.9995726546602812 0.0089765835339631 2 P51572 1 +Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672] 0.8188723342097602 2.981643300562741 0.0028670583233938 0.9995726546602812 0.0089765835339631 2 P51572 1 +SUN coiled coil domain 2 [IPR040994] 0.8141980718667928 2.958587993145005 0.0030905199414941 0.9997667769706212 0.0094570610214236 2 O94901 1 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8705057000877038 2.951830684159383 0.0031589609547066 0.9998062656436616 0.0096012514056439 4 Q96CP7,Q96G23,P27544 3 +BSD domain [IPR005607] 0.8121530820917409 2.9484799147158496 0.0031934089012508 0.9998235366870928 0.009695045900202 2 Q9NW68 1 +Saposin B type domain [IPR008139] 0.8060181127665902 2.9180771818392066 0.0035219716177736 0.99992758991344 0.0103102571085855 2 P07602 1 +ABC1 atypical kinase-like domain [IPR004147] 0.7978381536663878 2.877355834621948 0.004010231040066 0.9999807390196128 0.0113225122991206 2 Q96D53 1 +ADCK3-like domain [IPR034646] 0.7978381536663878 2.877355834621948 0.004010231040066 0.9999807390196128 0.0113225122991206 2 Q96D53 1 +Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252] 0.8211572180011764 2.853616974894886 0.0043224611420991 0.9999917442829224 0.0118602205997139 3 Q8NF37,Q86UL3 2 +Pleckstrin homology domain 8 [IPR041680] 0.7919953257376575 2.848139116268808 0.0043975696834461 0.9999932666421958 0.0119060453754224 2 Q9H4L5 1 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.817508037980845 2.835864489936857 0.0045701832644853 0.9999957853297956 0.0121661430351126 3 P61289 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.817508037980845 2.835864489936857 0.0045701832644853 0.9999957853297956 0.0121661430351126 3 P61289 1 +Armadillo repeat-containing domain [IPR006911] 0.7873210633946965 2.8246871440649097 0.0047326801537888 0.9999972886330508 0.0124601432874279 2 Q8N2F6 1 +Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.8093034377602766 2.7958041721463385 0.0051770759248201 0.999999188834932 0.0132804755752142 3 P16435 1 +FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.8093034377602766 2.7958041721463385 0.0051770759248201 0.999999188834932 0.0132804755752142 3 P16435 1 +Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.8093034377602766 2.7958041721463385 0.0051770759248201 0.999999188834932 0.0132804755752142 3 P16435 1 +Acyltransferase, C-terminal domain [IPR032098] 0.8077147866744558 2.788023739209562 0.0053030657663315 0.9999994239158336 0.0134209511723806 3 Q9NUQ2,Q92604 2 +Synaptotagmin, SMP domain [IPR039010] 0.7770961145194253 2.773140437981532 0.0055518155587612 0.999999706914604 0.013775028135696 2 A0FGR8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.7770961145194253 2.773140437981532 0.0055518155587612 0.999999706914604 0.013775028135696 2 A0FGR8 1 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.7770961145194253 2.773140437981532 0.0055518155587612 0.999999706914604 0.013775028135696 2 A0FGR8 1 +Extended synaptotagmin, C2A domain [IPR037733] 0.7770961145194253 2.773140437981532 0.0055518155587612 0.999999706914604 0.013775028135696 2 A0FGR8 1 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.7770961145194253 2.773140437981532 0.0055518155587612 0.999999706914604 0.013775028135696 2 A0FGR8 1 +Complex 1 LYR protein domain [IPR008011] 0.795441262419656 2.72765410533708 0.006378645512 0.9999999690317498 0.015279344125376 3 Q9Y6M9,Q9NU23 2 +Tim10-like [IPR004217] 0.8196878169997122 2.7113090730032576 0.0067018124673312 0.9999999871413484 0.0156646170300424 4 Q9Y5J9,Q9Y5J7 2 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.7598597721297129 2.6854754032206123 0.0072426705484467 0.99999999704837 0.0165284593090397 2 Q15067 1 +Serine aminopeptidase, S33 [IPR022742] 0.7557697925796097 2.6645296393441007 0.0077096072134004 0.9999999991720552 0.0172731000751309 2 Q8N2K0 1 +Peptidase M41 [IPR000642] 0.7508033888401977 2.639020619478786 0.0083145923555545 0.9999999998406548 0.0182927372573167 2 Q96TA2 1 +EF-hand domain [IPR002048] 0.5058039671423656 2.5997022591081373 0.0093304675895993 0.9999999999900084 0.0197577769804838 45 O95202,P60660,Q8NF37,Q9NWM8,O43852,Q9Y680,O75071,P80303,Q02818,Q14257,Q8IYU8,Q9BRK5,P41208,Q6NUK1,O95302 15 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.7417470055506868 2.5922914726738995 0.0095338959205317 0.9999999999942636 0.0201514434924958 2 P13674 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.7405784399649409 2.5862417946243417 0.0097028837725257 0.9999999999963824 0.0203076622411808 2 P55011 1 +SLC12A transporter, C-terminal [IPR018491] 0.7405784399649409 2.5862417946243417 0.0097028837725257 0.9999999999963824 0.0203076622411808 2 P55011 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.7891906122801605 2.563384749152196 0.0103657108794639 0.9999999999994076 0.0212504937756536 4 Q16352,P08670 2 +Arf GTPase activating protein [IPR001164] 0.7614275103500736 2.557905780450186 0.010530461951594 0.999999999999622 0.0215066577424089 3 Q8N6H7 1 +FAD dependent oxidoreductase [IPR006076] 0.773146984662744 2.4844543382319584 0.0129750147039375 0.9999999999999996 0.0253397048791854 4 Q8NCN5 1 +Syntaxin, N-terminal domain [IPR006011] 0.7443015780245461 2.471049516432202 0.0134717163692514 1.0 0.0260749123422045 3 O15400,Q12846 2 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7998479057890941 2.4645866369302003 0.0137171397286983 1.0 0.0264551831170185 7 P35670,Q9NQ11,P16615,Q9HD20,P05023 5 +MRG domain [IPR026541] 0.7110721589249286 2.4319456651487985 0.0150179600123658 1.0 0.0281139127928141 2 Q9UBU8 1 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7620578778135172 2.4294436119383893 0.0151220169964196 1.0 0.02821801790354 4 P98194,P16615,P05023 3 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7620578778135172 2.4294436119383893 0.0151220169964196 1.0 0.02821801790354 4 P98194,P16615,P05023 3 +GOLD domain [IPR009038] 0.7916356692338524 2.4247411737170457 0.0153193042557027 1.0 0.028448632370384 7 Q15363,Q9Y3B3,Q7Z7H5,P49755,Q9Y3A6 5 +Lamin tail domain [IPR001322] 0.7291057860900058 2.393189268899522 0.0167026224548618 1.0 0.0303908995778025 3 Q03252,P02545 2 +Peptidase M28 [IPR007484] 0.7547044083296137 2.39275768905386 0.0167222807655362 1.0 0.0304061928859212 4 Q969V3 1 +Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.7034764826175927 2.3917407677140496 0.0167686815197285 1.0 0.0304700588206499 2 Q9UID3 1 +Ion transporter-like, CBS domain [IPR044751] 0.7028921998247266 2.3886397791228475 0.0169108740525485 1.0 0.0305771412085559 2 Q8NE01 1 +CNNM, transmembrane domain [IPR002550] 0.7028921998247266 2.3886397791228475 0.0169108740525485 1.0 0.0305771412085559 2 Q8NE01 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.7148707018584342 2.319567793504607 0.0203642697914054 1.0 0.0350165563410365 3 P52888 1 +Immunoglobulin C1-set [IPR003597] 0.7583602068064087 2.3187019058846614 0.0204112051210705 1.0 0.0350165563410365 5 P30511,P55899 2 +MHC class I-like antigen recognition-like [IPR011161] 0.7583602068064087 2.3187019058846614 0.0204112051210705 1.0 0.0350165563410365 5 P30511,P55899 2 +Target SNARE coiled-coil homology domain [IPR000727] 0.7140964576647041 2.3141029097515795 0.0206620778523958 1.0 0.0353571465213258 13 P56962,O95721,O15400,O43752,O60499,O15155,Q13190,Q9UEU0 8 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7375036539023849 2.306295222986382 0.0210941418890777 1.0 0.0358919215266298 4 P13674,Q6PK18,O15460 3 +EB1, C-terminal [IPR004953] 0.6871165644171797 2.304462425716001 0.0211966992367089 1.0 0.0359984169312304 2 Q15555 1 +Histidine kinase domain [IPR005467] 0.7115721800116885 2.302413400831081 0.0213118699606522 1.0 0.0360806219509288 3 O14874,Q15118 2 +Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955] 0.7115721800116885 2.302413400831081 0.0213118699606522 1.0 0.0360806219509288 3 O14874,Q15118 2 +Band 7 domain [IPR001107] 0.7566929700989043 2.2883871227948505 0.0221149868835572 1.0 0.037022735166897 8 P35232,O75477,Q99623,O94905,P27105,Q9UJZ1 6 +LEM domain [IPR003887] 0.7655424193522884 2.2630646692772793 0.023631703091814 1.0 0.0388888457441395 6 P42167,P50402,Q9Y2U8 3 +Longin domain [IPR010908] 0.6969923254846779 2.226158713458415 0.0260035523294832 1.0 0.0421485293306921 3 O75396 1 +v-SNARE, coiled-coil homology domain [IPR042855] 0.6969923254846779 2.226158713458415 0.0260035523294832 1.0 0.0421485293306921 3 O75396 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.6880587830935754 2.179087246206378 0.0293251875247773 1.0 0.0461214532549175 3 P10321 1 +3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.6634531113058757 2.1765560743709114 0.0295137055647496 1.0 0.0463101233658266 2 Q16836 1 +3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.6634531113058757 2.1765560743709114 0.0295137055647496 1.0 0.0463101233658266 2 Q16836 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.7114480239276606 2.1735758876123827 0.0297370008992865 1.0 0.0466334163841394 4 P30511,P10321 2 +Intermediate filament, rod domain [IPR039008] 0.7301726660813678 2.154265075425477 0.0312193900764903 1.0 0.0484193401679703 8 P07196,P48681,Q03252,P07197,Q16352,P08670,P02545 7 +Zinc finger, CHHC-type [IPR012996] 0.6770894213910115 2.1209265478232435 0.0339279841693076 1.0 0.0516761066659916 3 P31943,P52597 2 +Glycosyltransferase 2-like [IPR001173] 0.7177423898070439 2.115200884769455 0.0344128295780155 1.0 0.0523260920201451 5 O60762,Q9Y673,Q10472 3 +Chromo domain subgroup [IPR017984] 0.6735827001753378 2.102249248063232 0.0355314478089834 1.0 0.0535150345484243 3 Q13185,P83916 2 +Chromo shadow domain [IPR008251] 0.6735827001753378 2.102249248063232 0.0355314478089834 1.0 0.0535150345484243 3 Q13185,P83916 2 +Dynamin, N-terminal [IPR045063] 0.7239956330070219 2.089083998411905 0.0367001625116818 1.0 0.0548169370406657 7 Q8IWA4,O60313 2 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.7239956330070219 2.089083998411905 0.0367001625116818 1.0 0.0548169370406657 7 Q8IWA4,O60313 2 +NOPS [IPR012975] 0.6691992986557633 2.078845208376777 0.0376315801297402 1.0 0.0558991366193282 3 P23246,Q8WXF1 2 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7173555372496301 2.055408819997787 0.039839534311433 1.0 0.0588547829394099 7 O15173,O43169 2 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.6412503651767503 2.0547449691887127 0.0399036440079563 1.0 0.0588547829394099 2 P04066 1 +SCP2 sterol-binding domain [IPR003033] 0.6630625365283415 2.0459724621963287 0.0407590801050363 1.0 0.0599189523633342 3 P22307,Q6YN16 2 +Phospholipid/glycerol acyltransferase [IPR002123] 0.7006354716097026 2.0367920463575477 0.0416708856931933 1.0 0.0605700871778116 9 Q9NUQ2,Q92604,Q643R3,Q86UL3,Q8NF37 5 +Immunoglobulin-like domain [IPR007110] 0.5795715210834101 1.9712573494413497 0.0486944471456021 1.0 0.0684559813670223 18 Q08722,P30511,P35613,P55899,Q9Y639,P78310 6 +COMM domain [IPR017920] 0.6405610753945109 1.92437440899708 0.0543076697917161 1.0 0.0746765006499833 3 Q9NX08,Q9Y6G5 2 +Domain of unknown function DUF5600 [IPR040990] 0.6172947706690106 1.9213665076367008 0.0546855178515108 1.0 0.0748532265627063 2 Q9H4M9 1 +EH domain-containing protein, N-terminal [IPR031692] 0.6172947706690106 1.9213665076367008 0.0546855178515108 1.0 0.0748532265627063 2 Q9H4M9 1 +SUN domain [IPR012919] 0.6266207519102147 1.8482092837187056 0.0645720729256034 1.0 0.0856943718295581 3 O94901 1 +FCP1 homology domain [IPR004274] 0.6187627435585449 1.80499969828477 0.0710747292465938 1.0 0.0925512859876128 3 Q3ZCQ8 1 +Zinc finger, TFIIB-type [IPR013137] 0.5790242477359119 1.7041740787747757 0.08834857033073 1.0 0.1105175171452003 2 P29083 1 +Fibronectin type II domain [IPR000562] 0.5987848113755977 1.6942686946997187 0.0902142364500508 1.0 0.1121761927694604 3 Q9UBV2 1 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.5898481800234954 1.644339656761158 0.1001060621111966 1.0 0.1221274969452649 3 Q9NRG0 1 +RNA polymerase Rpb4/RPC9, core [IPR006590] 0.564125036517685 1.6183080712352411 0.105596222136336 1.0 0.1271483922515062 2 O75575 1 +DALR anticodon binding [IPR008909] 0.5617879053461992 1.6047755608395564 0.1085432061786821 1.0 0.1295995329627924 2 Q5T160 1 +Arginyl-tRNA synthetase, catalytic core domain [IPR035684] 0.5617879053461992 1.6047755608395564 0.1085432061786821 1.0 0.1295995329627924 2 Q5T160 1 +Thioredoxin domain [IPR013766] 0.4393325818324846 1.5943444960401447 0.1108588967012635 1.0 0.1316662588513469 27 Q9H1E5,Q9Y320,Q96J42,Q9H3N1,Q6ZRP7,O43819 6 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.5634132086499026 1.4952959408070403 0.1348372240038584 1.0 0.1538556500246729 3 Q9ULX6,Q5BKZ1 2 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.5849445657365251 1.4704065911758115 0.1414516673107171 1.0 0.1605217996949003 11 Q9NWM8,Q9Y680 2 +MIRO domain [IPR020860] 0.5322816243061688 1.4325480832084845 0.1519870275572401 1.0 0.1705435832473683 2 Q8IXI1 1 +EF hand associated, type-2 [IPR013567] 0.5322816243061688 1.4325480832084845 0.1519870275572401 1.0 0.1705435832473683 2 Q8IXI1 1 +EF hand associated, type-1 [IPR013566] 0.5322816243061688 1.4325480832084845 0.1519870275572401 1.0 0.1705435832473683 2 Q8IXI1 1 +Far upstream element-binding protein, C-terminal [IPR015096] 0.524685947998846 1.3878300236519667 0.165188810095878 1.0 0.1837546994150113 2 Q96AE4 1 +CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.5194274028629989 1.3567894714423594 0.1748481138162296 1.0 0.1924038963644597 2 Q9NWU2 1 +CRA domain [IPR013144] 0.5194274028629989 1.3567894714423594 0.1748481138162296 1.0 0.1924038963644597 2 Q9NWU2 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.5782101261361843 1.3461898545822435 0.1782412961315134 1.0 0.1956165646414903 8 P28288,P08183,Q03519,Q03518,O75027,P33527 6 +PSI domain [IPR016201] 0.5365199012273953 1.3418033423306748 0.1796597682239507 1.0 0.1970132685637641 3 P05556 1 +Brdt, bromodomain, repeat I [IPR043508] 0.5353594389246029 1.3351430794237082 0.1818295222334978 1.0 0.1989082465890328 3 Q15059,O60885 2 +NET domain [IPR027353] 0.5353594389246029 1.3351430794237082 0.1818295222334978 1.0 0.1989082465890328 3 Q15059,O60885 2 +Brdt, bromodomain, repeat II [IPR043509] 0.5353594389246029 1.3351430794237082 0.1818295222334978 1.0 0.1989082465890328 3 Q15059,O60885 2 +Adenylate kinase, active site lid domain [IPR007862] 0.5344827586206724 1.3301096969669362 0.1834821310428545 1.0 0.2005536885427964 3 Q9UIJ7,P27144 2 +Ricin B, lectin domain [IPR000772] 0.5679597585889842 1.3237883870396536 0.1855733340202483 1.0 0.2024300155521643 5 Q10472,Q9UBG0 2 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.5059888986269464 1.2771874179783715 0.2015360879409491 1.0 0.2187828483794474 2 O43390 1 +AMPK, C-terminal adenylate sensor domain [IPR032270] 0.5042360502483347 1.26677786614432 0.2052347285406592 1.0 0.2226191234511687 2 Q13131 1 +F-BAR domain [IPR031160] 0.4998539293017909 1.2407298133368487 0.214705576891355 1.0 0.2325188251544855 2 Q9UKS6 1 +FCH domain [IPR001060] 0.4998539293017909 1.2407298133368487 0.214705576891355 1.0 0.2325188251544855 2 Q9UKS6 1 +AMP-binding enzyme, C-terminal domain [IPR025110] 0.5513713622759273 1.23282015515424 0.2176428699081589 1.0 0.2354167471944938 5 Q9UKU0,O14975 2 +Exosome complex component, N-terminal domain [IPR025721] 0.4957639497516923 1.2163891708163783 0.2238367072389384 1.0 0.2419227131838446 2 Q9Y3B2 1 +Ubiquitin-like domain, USP-type [IPR028135] 0.4910896874087181 1.18854012143784 0.2346206826692731 1.0 0.2528699978350124 2 Q13107 1 +Major sperm protein (MSP) domain [IPR000535] 0.5093512565750862 1.1852292471169157 0.2359268191221712 1.0 0.2540750359777229 3 Q8NHP6,O95292 2 +NudC N-terminal domain [IPR025934] 0.4846625766871275 1.1502004489420576 0.2500613213753744 1.0 0.268014950557819 2 Q9Y266 1 +Rad60/SUMO-like domain [IPR022617] 0.4843704352906985 1.1484565913730953 0.2507801231302917 1.0 0.2686787837819382 2 P61956 1 +Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.4834940111013864 1.143224477245289 0.2529454020114268 1.0 0.2706766242514357 2 Q08170 1 +Tankyrase 1-binding protein, C-terminal [IPR032764] 0.4832018697049363 1.1414802624263372 0.2536701210092165 1.0 0.271344682092994 2 Q9C0C2 1 +Heat shock chaperonin-binding [IPR006636] 0.5153463899444751 1.111486351968221 0.2663590614641284 1.0 0.2843548732027163 4 P54727,Q9NRR5,Q9BSL1 3 +Ubiquitin system component CUE [IPR003892] 0.5146800128950046 1.10773532744428 0.2679761376324108 1.0 0.285968216383402 4 Q9UKV5 1 +CRIB domain [IPR000095] 0.4929865575686573 1.090430571456441 0.2755235211838043 1.0 0.2937902739694709 3 O96013,Q13177 2 +AMP-dependent synthetase/ligase [IPR000873] 0.5345737265795973 1.082638749622151 0.2789688006405559 1.0 0.2973466269549437 7 Q9UKU0,O14975 2 +Ribosomal protein S10 domain [IPR027486] 0.472392638036811 1.0768933189401306 0.2815279282069596 1.0 0.2998377855795052 2 Q96GC5 1 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.5323370575135766 1.070342401683545 0.284465215142748 1.0 0.3026082721715374 7 P13674,Q6PK18,O15460 3 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.5323370575135766 1.070342401683545 0.284465215142748 1.0 0.3026082721715374 7 P13674,Q6PK18,O15460 3 +Cyclin, C-terminal domain [IPR004367] 0.465089103125913 1.0332175011720763 0.3015021245183678 1.0 0.3201016661880667 2 O95067 1 +Translation initiation factor IF- 2, domain 3 [IPR023115] 0.4642126789366246 1.0279756629192238 0.3039612758651659 1.0 0.3224591155821273 2 P46199 1 +Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.4627519719544249 1.0192392273800228 0.3080894077306602 1.0 0.3261981111631049 2 P29692 1 +Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.4627519719544249 1.0192392273800228 0.3080894077306602 1.0 0.3261981111631049 2 P29692 1 +Arfaptin homology (AH) domain [IPR010504] 0.4624598305579919 1.0174919477949975 0.3089194608945593 1.0 0.3269488379698783 2 P53365 1 +Ribosomal protein S7 domain [IPR023798] 0.4612912649722446 1.0105029044014422 0.3122544086308703 1.0 0.3300905368234004 2 Q9Y2R9 1 +OCRE domain [IPR041591] 0.4783752191700784 1.0056517538648777 0.314583118973573 1.0 0.3324222086298766 3 P52756,P98175 2 +Small GTP-binding protein domain [IPR005225] 0.330185138549116 0.9980163573072408 0.3182714268970796 1.0 0.3361425221597836 51 P62820,Q9NR31,Q9H0U4,P20339,P61019,P61026,Q15907,P61225,Q9NP72,P20340,Q969Q5,Q9BZG1 12 +CBS domain [IPR000644] 0.5209549534007917 0.98906421527438 0.3226317244060606 1.0 0.3405277028692092 6 P51790 1 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.4932667609254992 0.987104028352792 0.3235916431541825 1.0 0.3414075048038271 4 O60749,Q9UNH7 2 +Occludin homology domain [IPR010844] 0.4481449021326309 0.9319134889427644 0.3513812359685691 1.0 0.3697165496834399 2 Q16625 1 +Ribosomal protein L26/L24, KOW domain [IPR041988] 0.4478527607362008 0.9301684738206346 0.3522838621345432 1.0 0.3705219912368765 2 Q96A35 1 +Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520] 0.4463920537540198 0.9214447695419063 0.3568182640558288 1.0 0.3748534018191483 2 O15228 1 +GPAT/DHAPAT, acyltransferase domain [IPR041728] 0.4463920537540198 0.9214447695419063 0.3568182640558288 1.0 0.3748534018191483 2 O15228 1 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.4529514903565177 0.8583302515022505 0.3907101295587616 1.0 0.4096619208644834 3 Q96F07,Q9NUQ9 2 +14-3-3 domain [IPR023410] 0.487569464755766 0.8084326660839162 0.4188415534583285 1.0 0.4379682188252335 6 P31946,Q04917,P27348,P63104,P62258 5 +DOCKER domain [IPR027357] 0.4236050248320161 0.7858312538970104 0.431966353810115 1.0 0.4509942380196796 2 Q14185 1 +C2 DOCK-type domain [IPR027007] 0.4236050248320161 0.7858312538970104 0.431966353810115 1.0 0.4509942380196796 2 Q14185 1 +YTH domain [IPR007275] 0.4398012857977792 0.7825223081713926 0.4339076802794011 1.0 0.4528460996967716 3 Q96MU7,Q9H6S0 2 +Sulfatase, N-terminal [IPR000917] 0.4198071866783621 0.7633573217173788 0.4452503250919846 1.0 0.4641459793204253 2 P15586 1 +Major facilitator superfamily domain [IPR020846] 0.4492163082026202 0.7400478148544266 0.4592709818139953 1.0 0.4785770122874721 4 Q14728 1 +tRNA-guanine(15) transglycosylase-like [IPR002616] 0.4145486415425201 0.7323246485100443 0.4639704382651466 1.0 0.4832876346154303 2 Q9H974 1 +Extended PHD (ePHD) domain [IPR034732] 0.4440222157264138 0.7112148118327054 0.4769511313456802 1.0 0.496043863316408 4 O94880,Q8IWS0,Q03164 3 +EGF-like calcium-binding domain [IPR001881] 0.4095822378031104 0.7031196193974515 0.4819812064027093 1.0 0.5010824238938517 2 Q07954 1 +Immunoglobulin subtype 2 [IPR003598] 0.4473019707971712 0.6715020273648746 0.5019007683763896 1.0 0.5211898063616467 11 P35613,Q9Y639,P78310 3 +Plexin, TIG domain 1 [IPR041019] 0.4034472684779443 0.6672031858904185 0.5046423564137594 1.0 0.5234332618157306 2 Q9UIW2 1 +Sema domain [IPR001627] 0.4034472684779443 0.6672031858904185 0.5046423564137594 1.0 0.5234332618157306 2 Q9UIW2 1 +Plexin, cytoplasmic RasGAP domain [IPR013548] 0.4034472684779443 0.6672031858904185 0.5046423564137594 1.0 0.5234332618157306 2 Q9UIW2 1 +L27 domain [IPR004172] 0.4340836012861782 0.6563443220726881 0.5116026059274819 1.0 0.5298391112365105 4 O14936,Q5T2T1,Q9NZW5 3 +L27 domain, C-terminal [IPR014775] 0.4340836012861782 0.6563443220726881 0.5116026059274819 1.0 0.5298391112365105 4 O14936,Q5T2T1,Q9NZW5 3 +Peptidase M16, N-terminal [IPR011765] 0.4511184618882239 0.6267729402503609 0.5308080835852036 1.0 0.5486776747694033 7 P22695 1 +Peptidase M16, C-terminal [IPR007863] 0.4511184618882239 0.6267729402503609 0.5308080835852036 1.0 0.5486776747694033 7 P22695 1 +IPT domain [IPR002909] 0.403565166569253 0.576963668462709 0.5639639988683265 1.0 0.5818368556480406 3 Q96KP1,Q9UIW2 2 +EH domain [IPR000261] 0.4127448114586526 0.5402900879239366 0.5889969930260981 1.0 0.6065052877883068 4 Q9H4M9,Q9H223,Q96D71 3 +Guanylate kinase-like domain [IPR008144] 0.4344645991807971 0.5383792326595708 0.5903152607255289 1.0 0.6073997846459935 7 Q5T2T1,Q07157,Q9UDY2,O14936,Q9NZW5,Q00013 6 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.4344645991807971 0.5383792326595708 0.5903152607255289 1.0 0.6073997846459935 7 Q5T2T1,Q07157,Q9UDY2,O14936,Q9NZW5,Q00013 6 +ABC transporter-like, ATP-binding domain [IPR003439] 0.414286575754283 0.5017122225647256 0.6158699655759938 1.0 0.6322494859370574 12 P28288,P08183,Q03519,Q9NUQ8,Q03518,O75027,P33527 7 +Immunoglobulin subtype [IPR003599] 0.408453388640898 0.4688462285899304 0.6391795536580425 1.0 0.6556807722035045 12 P35613,Q9Y639,P78310 3 +Class II aldolase/adducin N-terminal [IPR001303] 0.3831092928112229 0.4646332421354289 0.6421941225929269 1.0 0.6582733381054964 3 Q9UEY8,P35611 2 +MCM domain [IPR001208] 0.4021643755483941 0.3646941475005804 0.7153397277882134 1.0 0.7282772963390176 6 P33991,P33993,Q14566,P49736,P33992 5 +MCM N-terminal domain [IPR027925] 0.4021643755483941 0.3646941475005804 0.7153397277882134 1.0 0.7282772963390176 6 P33991,P33993,Q14566,P49736,P33992 5 +MCM, AAA-lid domain [IPR041562] 0.4021643755483941 0.3646941475005804 0.7153397277882134 1.0 0.7282772963390176 6 P33991,P33993,Q14566,P49736,P33992 5 +MCM OB domain [IPR033762] 0.4021643755483941 0.3646941475005804 0.7153397277882134 1.0 0.7282772963390176 6 P33991,P33993,Q14566,P49736,P33992 5 +Glycoside hydrolase family 31, N-terminal domain [IPR025887] 0.3494011101373001 0.36343745998345 0.7162781230227724 1.0 0.7289579994002 2 P10253 1 +Plectin/S10, N-terminal [IPR005326] 0.3423897166228485 0.3265034494974294 0.744043479858082 1.0 0.7553831715709298 2 P46783 1 +HDGF-related, PWWP domain [IPR035496] 0.3693938372276885 0.316371632124778 0.7517204462870817 1.0 0.7624431853857713 4 Q7Z4V5 1 +Cyclin, N-terminal [IPR006671] 0.3530099357101128 0.3074714742488261 0.7584845323574649 1.0 0.7690150868404767 3 P14635,O95067 2 +Ku70/Ku80, N-terminal alpha/beta [IPR005161] 0.3362547472976877 0.2948298807672338 0.7681238389383374 1.0 0.7779125235424991 2 P13010 1 +Ku70/Ku80 C-terminal arm [IPR005160] 0.3362547472976877 0.2948298807672338 0.7681238389383374 1.0 0.7779125235424991 2 P13010 1 +Ku70/Ku80 beta-barrel domain [IPR006164] 0.3362547472976877 0.2948298807672338 0.7681238389383374 1.0 0.7779125235424991 2 P13010 1 +Cyclin-like [IPR013763] 0.3531131248173014 0.2384165219671807 0.8115580541698519 1.0 0.8200560442658713 4 P14635,Q00403,O95067 3 +Glutathione S-transferase, N-terminal [IPR004045] 0.372132956445269 0.2291007392154588 0.8187906189316925 1.0 0.82705504760876 7 Q9H7Z7 1 +cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.3026584867075583 0.1343903895973927 0.8930938806884834 1.0 0.9010977093428983 2 P10644 1 +CHCH [IPR010625] 0.3006134969325089 0.1254529337804376 0.9001649839825809 1.0 0.90789316413622 2 P51970 1 +Staufen, C-terminal [IPR032478] 0.3001168907071929 0.0691416419189159 0.9448768748615824 1.0 0.9522779992077568 3 O75569,O95793 2 +Disulphide isomerase [IPR005788] 0.3230994152046808 0.0660224551709892 0.9473599478151258 1.0 0.9537133304755848 5 P07237,P13667,Q15084,P30101 4 +LSM domain, eukaryotic/archaea-type [IPR001163] 0.3202576112412179 0.0200169731471315 0.984029832664702 1.0 0.9895231142017212 9 Q9UK45,P62318,Q9Y4Y9,P62312,Q9Y4Z0,P62314,P62304,P62316 8 +UBX domain [IPR001012] 0.3191163783392599 0.0137622605817288 0.9890196513738556 1.0 0.9938010777285824 7 Q96CS3 1 +von Willebrand factor, type A [IPR002035] 0.3183104409202204 0.0111405213099442 0.9911113339117386 1.0 0.99553264841246 6 O75131 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a445bec384a9478a1622ab8acd36f03a24482fb8 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain [IPR002073]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC-type uncharacterised transport system [IPR019196]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abl interactor 2, SH3 domain [IPR035726]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein ClpS, core [IPR003769]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-(1,6)-fucosyltransferase, N- and catalytic domain [IPR045573]", "Alpha-(1,6)-fucosyltransferase, SH3 domain [IPR035653]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-dystroglycan N-terminal domain 2 [IPR041631]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Arrestin C-terminal-like domain [IPR011022]", "Arrestin-like, N-terminal [IPR011021]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related protein 13, N-terminal [IPR018731]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BET1, SNARE domain [IPR039899]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CKK domain [IPR014797]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COQ9 [IPR013718]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calmodulin-regulated spectrin-associated protein, CH domain [IPR022613]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centromere protein H, C-terminal [IPR008426]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Connexin, N-terminal [IPR013092]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cupin-like domain 8 [IPR041667]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DG-type SEA domain [IPR030398]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4592 [IPR028030]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "Dystroglycan, C-terminal [IPR008465]", "Dystroglycan-type cadherin-like [IPR006644]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase AMFR, Ube2g2-binding region [IPR040675]", "E3 ubiquitin-protein ligase UBR-like, C-terminal [IPR044046]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAK1/PYK2, FERM domain C-lobe [IPR041784]", "FAM3C (ILEI) domain [IPR039475]", "FAM91, C-terminal domain [IPR028097]", "FAM91, N-terminal domain [IPR028091]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "FeS cluster biogenesis [IPR000361]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focal adhesion kinase, N-terminal [IPR041390]", "Focal adhesion kinase, targeting (FAT) domain [IPR005189]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GA-binding protein alpha subunit, N-terminal [IPR024668]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRAMDC4, PH-GRAM domain [IPR037845]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gamma-tubulin complex component 6, N-terminal [IPR045818]", "Gap junction protein, cysteine-rich domain [IPR019570]", "Gasdermin, PUB domain [IPR041263]", "Gasdermin, pore forming domain [IPR040460]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Germinal-centre associated nuclear protein, CID domain [IPR031910]", "Germinal-centre associated nuclear protein, MCM3AP domain [IPR031907]", "Germinal-centre associated nuclear protein, nucleoporin homology domain [IPR031908]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycolipid transfer protein domain [IPR014830]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyl transferase, family 28, C-terminal [IPR007235]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase family 23 (GT23) domain [IPR027350]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock factor (HSF)-type, DNA-binding [IPR000232]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase complex subunit SAP30 zinc-finger [IPR025717]", "Histone deacetylase complex subunit SAP30, Sin3 binding domain [IPR025718]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "Hypoxia induced protein, domain [IPR007667]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Impact, N-terminal [IPR001498]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KOW [IPR005824]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM2, LYR domain [IPR045293]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Liprin-beta, SAM domain repeat 1 [IPR037617]", "Liprin-beta, SAM domain repeat 2 [IPR037618]", "Liprin-beta, SAM domain repeat 3 [IPR037619]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "LysM domain [IPR018392]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M28 Zn-Peptidase Glutaminyl Cyclase [IPR037457]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MCM3AP, RNA recognition motif [IPR034265]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIR motif [IPR016093]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTMR6, PH-GRAM domain [IPR035998]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin Light Chain Kinase 1, Kinase domain [IPR015725]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH dehydrogenase subunit 5, C-terminal [IPR010934]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal [IPR001516]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFA6, LYR domain [IPR045299]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NEMO, Zinc finger [IPR034735]", "NET domain [IPR027353]", "NF-kappa-B essential modulator NEMO, CC2-LZ domain [IPR032419]", "NF-kappa-B essential modulator NEMO, N-terminal [IPR021063]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Opioid growth factor receptor (OGFr) conserved domain [IPR006757]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAS domain [IPR000014]", "PAS fold [IPR013767]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Par3/HAL, N-terminal [IPR021922]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, TIG domain 2 [IPR041362]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plexin-A1, Sema domain [IPR042744]", "Plus-3 domain [IPR004343]", "Pointed domain [IPR003118]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-mRNA-splicing factor SLU7 domain [IPR021715]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein FAM210A/B-like domain [IPR009688]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RING1 , RING finger, HC subclass [IPR042741]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Rhs repeat-associated core [IPR022385]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD3, SET domain [IPR044428]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAR protein, homodimerisation region [IPR032377]", "STARD11, START domain [IPR041952]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein LSm5 [IPR033871]", "Sm-like protein Lsm4 [IPR034101]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of fused C-terminal [IPR024314]", "Suppressor of fused-like domain [IPR020941]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBC1D8B, PH-GRAM domain 1 [IPR036012]", "TBC1D8B, PH-GRAM domain 2 [IPR036015]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TNF receptor-associated factor 2, MATH domain [IPR037305]", "TNF receptor-associated factor, BIRC3 binding domain [IPR032070]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Teneurin intracellular, N-terminal [IPR009471]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 7, N-terminal [IPR045819]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thg1 C-terminal domain [IPR025845]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Tox-GHH domain [IPR028916]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription factor Tfb2, C-terminal domain [IPR040662]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBAC2, UBA domain [IPR041928]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate heat shock transcription factor, C-terminal domain [IPR010542]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain [IPR030383]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vesicle transport v-SNARE, N-terminal [IPR007705]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vps72/YL1, C-terminal [IPR013272]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, TRAF-type [IPR001293]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNAHis guanylyltransferase catalytic domain [IPR024956]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD13", "ABHD16A", "ABHD6", "ABI2", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG13", "ALG5", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "APMAP", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL8B", "ARMC10", "ARMCX3", "ARMT1", "ARRB2", "ARSA", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7B", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS3", "BCKDHA", "BCKDHB", "BCKDK", "BCS1L", "BET1", "BIRC6", "BLM", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "CABLES1", "CACYBP", "CAD", "CADM1", "CALU", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC97", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPH", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNPY2", "COA3", "COASY", "COG4", "COIL", "COL4A3BP", "COLEC12", "COMMD10", "COMMD7", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1C", "CORO7", "COTL1", "COX2", "CPD", "CPNE1", "CPNE3", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRCP", "CRK", "CRKL", "CRMP1", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAG1", "DAGLB", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCP1A", "DCTD", "DCTN1", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DHCR24", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM129B", "FAM208A", "FAM210A", "FAM210B", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GJC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPN1", "GPR89B", "GPS1", "GRAMD4", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2H4", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "IBTK", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC1", "ISOC2", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2C", "ITPRIP", "IVD", "IWS1", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1211", "KIAA1468", "KIAA1671", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LSM12", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MBLAC2", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED25", "MEPCE", "METAP2", "METTL13", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGME1", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL2", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCBP1", "NCKIPSD", "NCL", "NCLN", "NCOR1", "NCSTN", "ND5", "NDUFA10", "NDUFA2", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NENF", "NES", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OFD1", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDZD11", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "POP1", "POR", "PPAN", "PPAT", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RAC3", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIF1", "RING1", "RIOX1", "RMND1", "RNASEH2A", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRP12", "RRP7A", "RSF1", "RSL24D1", "RTCA", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC18B1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC2A1", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNIP1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDP2", "TDRKH", "TECR", "TEDC1", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSR1", "TSTA3", "TTC4", "TTC7B", "TTF1", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TXNRD2", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URGCP", "UROD", "USO1", "USP10", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VPS13A", "VPS16", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YBX3", "YES1", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCF3", "ABHD12", "ACOX1", "ACSL6", "ADD1", "ADD3", "AGK", "AGPAT5", "AK3", "AK4", "AKAP8L", "ALG1", "ALG5", "AMFR", "ARFGAP2", "ARFIP2", "ARMC10", "ATAD3A", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2C1", "ATP7B", "BCAP31", "BCKDK", "BET1", "BRD3", "BRD4", "BSDC1", "BSG", "CALU", "CASK", "CBX1", "CBX3", "CCNB1", "CCNB2", "CD47", "CERS1", "CERS2", "CETN2", "CHRAC1", "CISD1", "CLCN3", "CNNM3", "COMMD10", "COMMD8", "COQ8B", "CPNE3", "CPT1A", "CRCP", "CXADR", "CYB5B", "CYFIP2", "DHCR24", "DOCK1", "DPM1", "EEF1D", "EFCAB14", "EHD1", "EHD4", "ELMO2", "EMD", "ENDOD1", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ESYT2", "EXOC2", "EXOSC1", "FAF2", "FAM49B", "FCGRT", "FKBP14", "FKBP7", "FKBP9", "FUBP1", "FUCA1", "GAA", "GALNT1", "GID8", "GNPAT", "GNS", "GPAT4", "GTF2B", "GTF2E1", "HADH", "HDGFL2", "HLA-C", "HLA-F", "HNRNPF", "HNRNPH1", "HNRNPR", "HSDL2", "INA", "ITGB1", "KMT2A", "LEMD3", "LETM1", "LMNA", "LMNB2", "LPCAT1", "LPCAT4", "LPGAT1", "LRP1", "LSM4", "LSM5", "LSM6", "LSM7", "LYRM2", "MAPRE2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MFN1", "MFSD10", "MICU2", "MORF4L1", "MOSPD2", "MPP1", "MPP6", "MPP7", "MRC2", "MRPL24", "MRPL48", "MRPS7", "MSMO1", "MTIF2", "MTX1", "MTX2", "MYL6", "NCLN", "NDUFA8", "NDUFB9", "NEFL", "NEFM", "NES", "NPTN", "NUCB1", "NUCB2", "NUDC", "OCLN", "OGFOD3", "OPA1", "OSBPL3", "P4HA1", "P4HA2", "P4HB", "PACSIN3", "PAK2", "PAK4", "PCYOX1L", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDPR", "PGRMC2", "PHB", "PHB2", "PHF14", "PHF6", "PLXNA1", "POR", "PRKAA1", "PRKAR1A", "PRKRA", "PSAP", "PSME3", "PSPC1", "PTGES2", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB34", "RAB5A", "RAB6A", "RAD23B", "RAP2B", "RARS2", "RBM10", "RBM5", "RCN2", "REPS1", "RHBDD2", "RHOT2", "RPS10", "RTN2", "RTN4", "SAR1A", "SCO2", "SCP2", "SDF4", "SEC22B", "SEL1L", "SFPQ", "SLC12A2", "SLC25A24", "SLC27A2", "SNAP29", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNX2", "SNX6", "SRSF4", "STAU1", "STOM", "STOML2", "STX10", "STX17", "STX4", "STX5", "STX6", "STX7", "SUMO2", "SUN1", "TAP1", "TAP2", "THOP1", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TLCD1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMPO", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TXNDC15", "UBAC1", "UBQLN4", "UQCRC2", "USP4", "VAPB", "VIM", "VPS51", "VTI1B", "XRCC5", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ", "ZNF326"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..744807fd3436d8746a0c2d9d26b0b44780b41bf3 --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "P-type ATPase [IPR001757]", "2": "Transmembrane emp24 domain-containing protein [IPR015720]", "3": "Syntaxin [IPR045242]", "4": "Small GTPase [IPR001806]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 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https://git-lfs.github.com/spec/v1 +oid sha256:3886890b065dabcb86bd0e755940cb3924d6d77c8a9d02006b6e269e1f275ccf +size 145429 diff --git a/interpro_family/basic/plot_6.png b/interpro_family/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..d076992a827c0cca07d363d9dccd27f76b336505 --- /dev/null +++ b/interpro_family/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dd7ec8a45dadece7b2dfbee99c2bba3faf39053d1d490fa30055df9338c4a0ba +size 143908 diff --git a/interpro_family/basic/plot_7.png b/interpro_family/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..ecff3c1969be8a8b63cf856ed313e781144cd8e7 --- /dev/null +++ b/interpro_family/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cb5641d1905747798f9ceb6a69d432ad6e2dd4b6da62ecf9264ed410223654c8 +size 132927 diff --git a/interpro_family/basic/plot_8.png b/interpro_family/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..5741ff63b7ea280d653a348e6c2c534d28efe270 --- /dev/null +++ b/interpro_family/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71293462922f529431da5c8f3714eda60ff4eb3590a03c458cada6c16d0b6174 +size 131221 diff --git a/interpro_family/basic/plot_9.png b/interpro_family/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..5036d6e5108ab8cb230628706e6c4f9d1e97ab47 --- /dev/null +++ b/interpro_family/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3623a1c8aee2203ea7bafae4dbc9dfd6a08949119a91627eeacc4b4279c7f9c9 +size 143963 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9a823af50bbe9c81a578e636672c20589539c91b --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8ea837d716693f7f9e3f664b283a56fe20ab73f1ee0097eae530c6b48622061 +size 926072 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0d0ebee643818707265ccb322342d597433c1473 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier protein [IPR002067] 11 13 2.752759858807877 0.0059095226314651 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 8.013345096433107e-08 1.0 0.1758008751515455 0.0011993766429203 1.4497628230363953e-07 +P-type ATPase [IPR001757] 5 7 2.4645866369302003 0.0137171397286983 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.015895687074825 1.0 1.0 1.0 0.0034992238505004 +Transmembrane emp24 domain-containing protein [IPR015720] 5 6 2.428170002217942 0.0151752281576942 2.6432038834951457 5.099514563106796 0.3626508447128717 0.2724944971681708 1.287119696753696 0.8431907483703972 1.4713835809049645 0.2794327521776852 0.0002518200710585 1.0 1.0 0.0148625463558957 0.0003286021100258 +Syntaxin [IPR045242] 6 8 2.333387015283535 0.0196278421493139 2.674757281553398 5.815533980582524 0.7134969984167514 0.3462495636510407 1.4434464182805606 1.4295601388514203 1.142372356309129 0.3001529293380739 0.0028972022089491 1.0 0.1265462710440741 0.0439142352380576 2.7323384312904545e-05 +Type 1 protein exporter [IPR039421] 4 5 2.14675548620456 0.0318127528526519 1.4660194174757282 4.152912621359223 0.6118345866928353 0.3423864070958426 1.2012577064447347 1.3414295599134654 1.163285659538929 0.2820720534042253 0.0478482703534769 1.0 1.0 0.1781979724676324 0.0542215392640632 +Small GTPase [IPR001806] 11 34 2.023001710945374 0.0430729711197717 10.635922330097088 30.694174757281555 -0.1943036334616698 0.6387958311735634 6.288645251623238 3.90775492972872 0.8353195472876326 0.3162305404371562 0.638424067433761 1.0 0.6060556355956216 0.6801132784401862 0.5017038371515101 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b92c5854ee568e6da4f946959e5d6beb2203393a --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 2628, + "title": "Average number of proteins per term", + "value": 1.296042617960426 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1ad1befda74e29fead124684f11cf3e6913ed91d --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ed365472f308024f1de7a89603ae89e8bc0a42cb --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,149 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9897750511247448 3.7812763669296414 0.0001560263453987 0.3363956910159447 0.0016775144325246 2 Q99595 1 +Haem oxygenase-like [IPR016053] 0.9833479404031552 3.75262124839233 0.0001749951460705 0.3686705769324261 0.0016979466461669 2 P09601 1 +Haem oxygenase [IPR002051] 0.9833479404031552 3.75262124839233 0.0001749951460705 0.3686705769324261 0.0016979466461669 2 P09601 1 +Cytochrome P450 [IPR001128] 0.978673678060182 3.7317165070512743 0.0001901794571534 0.3933717686321881 0.0017365320819482 2 Q6UW02 1 +Prenylcysteine oxidase [IPR017046] 0.9699094361671072 3.692372056306471 0.0002221721186133 0.4422994988333171 0.0017751689548553 2 Q8NBM8 1 +Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708] 0.9646508910312592 3.668671907552413 0.0002438137281324 0.4731400952323653 0.0018145523092481 2 Q8N8Q8 1 +Yif1 family [IPR005578] 0.959684487291851 3.646223509408171 0.00026612252714 0.5031479964924763 0.0018550928417086 2 Q5BJH7 1 +Nucleobindin [IPR040250] 0.9570552147239288 3.634313382583122 0.0002787219144879 0.5193343137581287 0.001885353761762 2 P80303 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.954425942156005 3.6223853951199176 0.0002918987963955 0.5356989014702398 0.0019177750923189 2 O96005 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.954425942156005 3.6223853951199176 0.0002918987963955 0.5356989014702398 0.0019177750923189 2 O96005 1 +Porin, eukaryotic type [IPR001925] 0.9824663939216832 3.6008583467270925 0.0003171683537028 0.5655396724034002 0.0019798537613566 3 P45880,P21796 2 +MICOS complex subunit MIC26/MIC27, animal [IPR033182] 0.9456617002629298 3.5824956293473433 0.0003403273125299 0.5912012929407242 0.0020129066346124 2 Q9BUR5 1 +MICOS complex subunit MIC26/MIC27 [IPR019166] 0.9456617002629298 3.5824956293473433 0.0003403273125299 0.5912012929407242 0.0020129066346124 2 Q9BUR5 1 +Mitochondrial carrier UCP-like [IPR002030] 0.9298860648553906 3.510184621448538 0.0004477956614747 0.6918197874931862 0.0023119980321331 2 Q9UBX3 1 +Transmembrane protein 126 [IPR009801] 0.9293017820625205 3.507493715193082 0.0004523490387662 0.6954872208957563 0.0023222822400643 2 Q9H061 1 +CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131] 0.927841075080343 3.5007624425132664 0.0004639291914201 0.7046188773104054 0.0023423879861433 2 Q9NZ45 1 +Cytochrome c oxidase subunit VIIa, metazoa [IPR003177] 0.91820040899796 3.4561917230198387 0.0005478654888346 0.7631160818175892 0.002566471487803 2 P14406 1 +Cytochrome c oxidase subunit VII [IPR039297] 0.91820040899796 3.4561917230198387 0.0005478654888346 0.7631160818175892 0.002566471487803 2 P14406 1 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.9173239848086476 3.4521273432357096 0.0005561851669568 0.7682419280800508 0.0025766433684319 2 P50416 1 +Tetraspanin, animals [IPR000301] 0.9421390999415544 3.4205741737287134 0.0006248909251966 0.806548156325084 0.0026900033255261 3 O60637,O43657 2 +Tetraspanin/Peripherin [IPR018499] 0.9421390999415544 3.4205741737287134 0.0006248909251966 0.806548156325084 0.0026900033255261 3 O60637,O43657 2 +Lysosome-associated membrane glycoprotein [IPR002000] 0.9103125912941888 3.419536738677791 0.000627278614582 0.8077589923869855 0.0026900033255261 2 P13473 1 +Protein-tyrosine phosphatase-like, PTPLA [IPR007482] 0.9000876424189348 3.3717660099674647 0.0007468787350719 0.8596380263087067 0.0029208293389421 2 Q6Y1H2 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.8974583698510091 3.359435140825164 0.0007810198215423 0.8716920490892693 0.0030051538667836 2 O43819 1 +Copper chaperone SCO1/SenC [IPR003782] 0.8974583698510091 3.359435140825164 0.0007810198215423 0.8716920490892693 0.0030051538667836 2 O43819 1 +Derlin [IPR007599] 0.8965819456617022 3.355320555241068 0.0007927306776669 0.8755837405168445 0.0030280468327161 2 Q9GZP9 1 +Palmitoyl protein thioesterase [IPR002472] 0.8945369558866548 3.345711481872931 0.0008207174579824 0.8844129143150867 0.0030776675611867 2 P50897 1 +Basigin-like [IPR043204] 0.8799298860648583 3.276731656352271 0.0010501612493758 0.936788808239689 0.00364153915087 2 P35613 1 +Tumour protein D52 [IPR007327] 0.8743791995325735 3.2503597159203395 0.0011525911759886 0.9517209016250692 0.0038293421118813 2 O43399 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.9353990061385592 3.248688075490924 0.0011593853650859 0.9525762609115384 0.0038345133719455 4 Q96HR9,Q00765,Q6NUK4 3 +Mpv17/PMP22 [IPR007248] 0.8670756646216822 3.2155242513899123 0.0013020649264223 0.9674199871861252 0.0041326408534275 2 Q567V2 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8661992404323726 3.2113335827934266 0.0013212046958392 0.9690202544537522 0.0041782502294412 2 Q9NVI7 1 +P-type ATPase, subfamily V [IPR006544] 0.8641542506573205 3.201546639940694 0.0013669194461123 0.972531673781692 0.0042512003602168 2 Q9HD20 1 +Prohibitin [IPR000163] 0.8586035641250445 3.174920342775758 0.001498776389879 0.980585575993536 0.0045476853236576 2 Q99623 1 +Mitofusin family [IPR027094] 0.8565585743499884 3.165087813476252 0.0015503615303154 0.9830504115840668 0.0046670676995061 2 Q8IWA4 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.8831092928112271 3.1490418076328575 0.0016380675884668 0.9865445531996092 0.0048587377229016 3 Q96RQ1,Q9Y282 2 +Nucleosome assembly protein (NAP) [IPR002164] 0.8810637054354159 3.1394623977493294 0.0016925813541897 0.9883432799934732 0.0049755076049334 3 P55209,Q99733 2 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.8670368205727661 3.0734587182556115 0.002115929606145 0.9961763671580528 0.0057794831877442 3 P12235,P12236 2 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.8375693835816629 3.0731916451683916 0.0021178243187967 0.9961953990575712 0.0057794831877442 2 Q9Y5J9 1 +Bcl-2 family [IPR026298] 0.860412969444976 3.042096393882116 0.0023493664617939 0.9979324668430916 0.0062225083333243 3 Q9BXK5 1 +Bcl2-like [IPR002475] 0.860412969444976 3.042096393882116 0.0023493664617939 0.9979324668430916 0.0062225083333243 3 Q9BXK5 1 +Erlin1/2 [IPR033294] 0.8282208588957111 3.0275512682601895 0.0024654388906677 0.9984771528324154 0.0064533599648155 2 O75477 1 +Heparan sulphate 2-O-sulfotransferase [IPR007734] 0.8217937481741269 2.9960184746248935 0.0027352986129114 0.9992520795090072 0.0069722257562863 2 Q7LGA3 1 +B-cell receptor-associated protein 29/31 [IPR008417] 0.8188723342097602 2.981643300562741 0.0028670583233938 0.9994714911853124 0.0071963985423868 2 P51572 1 +Zinc/iron permease [IPR003689] 0.8185801928133214 2.9802043306817856 0.0028805616855978 0.999489969579672 0.0072165072542907 2 Q15043 1 +Eukaryotic porin/Tom40 [IPR027246] 0.874341440214516 2.9696915069270933 0.0029809894130057 0.9996085841585478 0.0073766856660819 4 P45880,P21796 2 +SUN domain-containing protein 1-5 [IPR045119] 0.8141980718667928 2.958587993145005 0.0030905199414941 0.9997067434546102 0.007590548043221 2 O94901 1 +Stomatin/HflK/HflC family [IPR001972] 0.805725971370142 2.916626485612488 0.0035383922288982 0.9999099715887956 0.0084215754277706 2 P27105 1 +ABC transporter Tap-like [IPR013305] 0.7995910020449977 2.886099664827793 0.0039004861912217 0.9999653606683748 0.0090312578947407 2 Q03519 1 +Sulfotransferase [IPR005331] 0.8220338983050981 2.8578758822685075 0.0042648717639155 0.999986757135609 0.0096063519666286 3 Q7LGA3,Q8NCH0 2 +ClpA/B family [IPR001270] 0.7937481741162731 2.8569155653368794 0.0042777961656073 0.999987201245729 0.009608588310441 2 Q15645 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.7905346187554818 2.840817901163149 0.0044997998782139 0.9999928768484608 0.009959956624401 2 Q93050 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.7905346187554818 2.840817901163149 0.0044997998782139 0.9999928768484608 0.009959956624401 2 Q93050 1 +Proteasome activator PA28 [IPR009077] 0.817508037980845 2.835864489936857 0.0045701832644853 0.9999940847126708 0.0100589963308772 3 P61289 1 +Prenylated rab acceptor PRA1 [IPR004895] 0.7881974875840021 2.8290897304194407 0.0046680608859304 0.9999954317781926 0.010231579656568 2 O60831 1 +Mitochondrial carrier protein [IPR002067] 0.7963905601207224 2.7527598588078774 0.0059095226314651 0.9999998280900724 0.0121997057937866 13 P53007,Q8TBP6,O43808,Q9BQT8,Q9HC21,P05141,Q9UJS0,P12236,Q96H78,Q6NUK1,P12235 11 +Calcium uptake protein 1/2/3 [IPR039800] 0.769208296815665 2.7331436082332012 0.0062732973411949 0.9999999342991648 0.0127405142292584 2 Q8IYU8 1 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.7665790242477455 2.719766040661739 0.006532811998934 0.9999999669271712 0.0130955224509525 2 Q9UM00 1 +Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311] 0.7654104586620063 2.713813155510636 0.0066513669398124 0.999999975830725 0.0132623613944061 2 Q9UKU0 1 +Nonaspanin (TM9SF) [IPR004240] 0.8175971938029818 2.7012559390324857 0.0069078158273145 0.999999987737642 0.0136187096730553 4 O15321,Q99805,Q92544 3 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.7598597721297129 2.6854754032206123 0.0072426705484467 0.999999994945568 0.0140652317521976 2 Q15067 1 +Acyl-CoA oxidase [IPR012258] 0.7598597721297129 2.6854754032206123 0.0072426705484467 0.999999994945568 0.0140652317521976 2 Q15067 1 +Peptidase, FtsH [IPR005936] 0.7508033888401977 2.639020619478786 0.0083145923555545 0.999999999704424 0.0154860019209052 2 Q96TA2 1 +Synaptobrevin [IPR001388] 0.7493426818580273 2.6315022820634195 0.0085008296235762 0.9999999998195698 0.0157267133787932 2 O75396 1 +CD36 family [IPR002159] 0.7446684195150579 2.6073955177347585 0.0091233908987942 0.9999999999653704 0.0165715430368144 2 Q14108 1 +Tropomyosin [IPR000533] 0.7706019871420202 2.6040500147234114 0.0092129311374835 0.999999999972691 0.0166976434684874 3 P67936,P09493 2 +Prolyl 4-hydroxylase [IPR045054] 0.7417470055506868 2.5922914726738995 0.0095338959205317 0.9999999999883448 0.0171375365794511 2 P13674 1 +SLC12A transporter family [IPR004842] 0.7405784399649409 2.5862417946243417 0.0097028837725257 0.9999999999925566 0.0173700126390991 2 P55011 1 +Cation efflux protein [IPR002524] 0.7632963179427299 2.567326873148664 0.0102485952204971 0.9999999999982516 0.0181711181088701 3 Q8NEW0,Q6NXT4 2 +Prefoldin beta-like [IPR002777] 0.7804319139528824 2.520390357151081 0.011722475243979 0.9999999999999653 0.0200956718468212 4 Q9NUG6 1 +High mobility group protein HMGN [IPR000079] 0.7277242185217689 2.5193897696739542 0.0117558442827878 0.999999999999968 0.0201397384453497 2 P05114 1 +Sorting nexin-5/6/32 [IPR014637] 0.7268477943324618 2.5148111863079725 0.0119096147196307 0.9999999999999788 0.0203236801838892 2 Q9UNH7 1 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.7518066189155588 2.5092281422458904 0.0120995310454443 0.9999999999999872 0.0205543423318861 3 Q9NPH0 1 +Glycosyl transferase, family 8 [IPR002495] 0.773912650663232 2.4882388594670344 0.0128377478729819 0.9999999999999982 0.0215575727860681 4 Q8NBI6,Q68CQ7 2 +P-type ATPase [IPR001757] 0.7998479057890941 2.4645866369302003 0.0137171397286983 0.9999999999999998 0.0227436234744601 7 P35670,Q9NQ11,P16615,Q9HD20,P05023 5 +MRG [IPR008676] 0.7110721589249286 2.4319456651487985 0.0150179600123658 1.0 0.0243901315153384 2 Q9UBU8 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.799649020181358 2.428170002217942 0.0151752281576942 1.0 0.0245267525205537 6 Q15363,Q9Y3B3,Q7Z7H5,P49755,Q9Y3A6 5 +Sodium/potassium-transporting ATPase subunit beta [IPR000402] 0.7099035933391762 2.425773325043903 0.0152758080777506 1.0 0.0246589825726834 2 P54709 1 +Kinesin light chain [IPR002151] 0.7331969608416147 2.414225495441073 0.0157686999594912 1.0 0.0253288026853643 3 Q9NSK0,Q07866 2 +Tricarboxylate/iron carrier [IPR004686] 0.731151373465808 2.4037142044585855 0.0162294557573885 1.0 0.0258490968063133 3 Q6P4A7,Q96NB2 2 +Ancient conserved domain protein family [IPR045095] 0.7028921998247266 2.3886397791228475 0.0169108740525485 1.0 0.0266711958145707 2 Q8NE01 1 +Tropomodulin [IPR004934] 0.7011393514461008 2.3793296799690755 0.0173441561394274 1.0 0.0271959679799613 2 Q9NYL9 1 +Syntaxin [IPR045242] 0.7656859119168079 2.333387015283535 0.0196278421493139 1.0 0.0300944977645256 8 P56962,O15400,O43752,Q9UNK0,O60499,Q13190 6 +Vacuolar protein sorting protein 26 related [IPR028934] 0.6914986853637173 2.3279324047804213 0.0199156932380957 1.0 0.0304470284058845 2 O14972 1 +Peptidase M3A/M3B [IPR045090] 0.7148707018584342 2.319567793504607 0.0203642697914054 1.0 0.0310351659164757 3 P52888 1 +SCAMP [IPR007273] 0.7388469424966462 2.313080366593999 0.0207182209529179 1.0 0.0314440449027407 4 O15127,O14828 2 +Microtubule-associated protein RP/EB [IPR027328] 0.6871165644171797 2.304462425716001 0.0211966992367089 1.0 0.0320880907799949 2 Q15555 1 +PDK/BCKDK protein kinase [IPR039028] 0.7115721800116885 2.302413400831081 0.0213118699606522 1.0 0.0322253131510898 3 O14874,Q15118 2 +Flotillin family [IPR027705] 0.6792287467134144 2.2620464039087302 0.0236945364357363 1.0 0.0350048849164422 2 Q14254 1 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.6951579449364684 2.216514826325583 0.0266562636220286 1.0 0.0383639982468189 3 Q14739 1 +Adenylate kinase 3/4, mitochondrial [IPR028586] 0.6672509494595459 2.1972174543522764 0.0280049196150142 1.0 0.0398838131213232 2 Q9UIJ7 1 +Type 1 protein exporter [IPR039421] 0.7239766081871549 2.14675548620456 0.0318127528526519 1.0 0.0440948916122201 5 Q03518,P08183,O75027,Q03519 4 +Glycoside hydrolase, family 29 [IPR000933] 0.6412503651767503 2.0547449691887127 0.0399036440079563 1.0 0.0531790209195685 2 P04066 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.6412503651767503 2.0547449691887127 0.0399036440079563 1.0 0.0531790209195685 2 P04066 1 +Small GTPase [IPR001806] 0.4759941572185215 2.023001710945374 0.0430729711197717 1.0 0.0567397333848421 34 P62820,Q9H0U4,P20339,P61019,P61026,Q15907,P61225,Q9NP72,P20340,Q969Q5,Q9BZG1 11 +KH domain-containing BBP-like [IPR045071] 0.6454108718376993 1.827747695574227 0.0675874263578617 1.0 0.0817770517810592 4 O75525 1 +TAF15/EWS/TLS family [IPR034870] 0.6186440677966074 1.8043456141411245 0.07117714320263 1.0 0.0851388413109295 3 Q01844,P35637 2 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.6142368755813516 1.7800236711847055 0.0750720868578469 1.0 0.0887491877023939 3 Q9HB40 1 +THRAP3/BCLAF1 family [IPR029199] 0.5828220858895792 1.7259472609196411 0.0843569011676319 1.0 0.0973900522170175 2 Q9Y2W1 1 +Short-chain dehydrogenase/reductase SDR [IPR002347] 0.5222848146190185 1.724115172506839 0.0846870535718089 1.0 0.0976558037677551 20 Q3SXM5,Q9Y394,Q9BY49,Q53GQ0,Q6UX07,Q8NBQ5,Q8TC12,Q96LJ7,Q8NBN7 9 +RNA polymerase subunit Rpb4/RPC9 [IPR005574] 0.564125036517685 1.6183080712352411 0.105596222136336 1.0 0.1166485379463182 2 O75575 1 +Arginine-tRNA ligase [IPR001278] 0.5617879053461992 1.6047755608395564 0.1085432061786821 1.0 0.1194520711212633 2 Q5T160 1 +NSF attachment protein [IPR000744] 0.5594507741747121 1.5912262914711537 0.111558657997322 1.0 0.1220042252255356 2 P54920 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.5585743499853962 1.586141028242697 0.1127073216179752 1.0 0.123004502164468 2 O75150 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.5634132086499026 1.4952959408070403 0.1348372240038584 1.0 0.1434043806888466 3 Q9ULX6,Q5BKZ1 2 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.5392930178206287 1.4736946088064404 0.1405638350701892 1.0 0.1488322959566709 2 P07910 1 +Clathrin light chain [IPR000996] 0.5372480280455777 1.4617070401588406 0.1438215071993753 1.0 0.1520365731777789 2 P09496 1 +Mitochondrial Rho GTPase [IPR021181] 0.5322816243061688 1.4325480832084845 0.1519870275572401 1.0 0.1596410505277486 2 Q8IXI1 1 +Glutathione Transferase family [IPR040079] 0.5801407831448621 1.412181862917432 0.1578964194469461 1.0 0.1649907714936677 10 Q5HYI7,Q9H7Z7,Q13505,O75431 4 +Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237] 0.5162138475021893 1.3377890516900173 0.1809652118298657 1.0 0.1872348727121602 2 Q9UBW8 1 +Adenylate kinase subfamily [IPR006259] 0.5344827586206724 1.3301096969669362 0.1834821310428545 1.0 0.1897642819286192 3 Q9UIJ7,P27144 2 +Vesicle-associated membrane-protein-associated protein [IPR016763] 0.5092024539877437 1.2962564333713202 0.194887152811193 1.0 0.2014012731371668 2 O95292 1 +Polyprenyl synthetase [IPR000092] 0.524254821741668 1.2712762384455991 0.2036303925583016 1.0 0.210354037595604 3 Q5T2R2,P14324 2 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.5545633573139888 1.2668351657198431 0.2052142351487405 1.0 0.2119068801457328 10 Q8N8L6,Q9NR31,P40616,Q9NXU5,P36404 5 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.4957639497516949 1.216389170816395 0.2238367072389322 1.0 0.2305930484609619 2 Q9NQT5 1 +HnRNP R/Q splicing factor [IPR006535] 0.5061367621273946 1.1666294179908872 0.2433600578428327 1.0 0.250215270739814 3 A0AV96,O43390 2 +Tankyrase 1-binding protein-like [IPR040006] 0.4832018697049363 1.1414802624263372 0.2536701210092165 1.0 0.2603065513519019 2 Q9C0C2 1 +Adaptor protein complex, sigma subunit [IPR016635] 0.4988310929281059 1.1243152440302528 0.2608793136410947 1.0 0.2675998580206077 3 P53680,Q92572 2 +ADP-ribosylation factor 1-5 [IPR045872] 0.4796961729477249 1.1205432600981915 0.2624823285807987 1.0 0.2691391180297849 2 P84085 1 +Snf7 family [IPR005024] 0.5322388292391327 1.0502566715816308 0.2936001202283225 1.0 0.3003429801323595 6 O43633 1 +Tight junction protein ZO [IPR005417] 0.4653812445223602 1.0349647679732097 0.3006853652184209 1.0 0.3073516685313147 2 Q9UDY2 1 +Cyclin [IPR039361] 0.465089103125913 1.0332175011720763 0.3015021245183678 1.0 0.3080667119884411 2 O95067 1 +Histidine phosphatase superfamily, clade-1 [IPR013078] 0.4827586206896422 1.0310895960798607 0.3024988061928941 1.0 0.3089649680042463 3 Q96HS1,P18669 2 +Translation initiation factor IF- 2 [IPR015760] 0.4642126789366246 1.0279756629192238 0.3039612758651659 1.0 0.3103380858483512 2 P46199 1 +Arfaptin family [IPR030798] 0.4624598305579919 1.0174919477949975 0.3089194608945593 1.0 0.3152778031964667 2 P53365 1 +Ribosomal protein S5/S7 [IPR000235] 0.4612912649722446 1.0105029044014422 0.3122544086308703 1.0 0.3185576808547853 2 Q9Y2R9 1 +Cytoplasmic FMR1-interacting [IPR008081] 0.4528191644756065 0.9598443642394464 0.3371335505021169 1.0 0.3434058026044819 2 Q96F07 1 +Ribosomal protein S9 [IPR000754] 0.4513584574934337 0.9511140108649097 0.341546503057645 1.0 0.347766063555014 2 P82933 1 +ELL/occludin family [IPR031176] 0.4481449021326309 0.9319134889427644 0.3513812359685691 1.0 0.3575028602885789 2 Q16625 1 +Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284] 0.4463920537540198 0.9214447695419063 0.3568182640558288 1.0 0.3628941168493491 2 O15228 1 +Small GTPase superfamily, ARF type [IPR024156] 0.4799766150248609 0.9122701020831512 0.3616265489928851 1.0 0.3674998340113311 4 P40616,P84085,Q96KC2 3 +YTH domain containing protein [IPR045168] 0.4396728016359894 0.8813510359474162 0.3781278507565901 1.0 0.3841205998408655 2 Q96MU7 1 +Sds3-like [IPR013907] 0.4370435290680688 0.8656814455452154 0.3866648778237138 1.0 0.3926411510512828 2 Q9H7L9 1 +CPSF6/7 family [IPR034772] 0.4303242769500395 0.8257001295618084 0.4089742187689398 1.0 0.4143347135407763 2 Q8N684 1 +14-3-3 protein [IPR000308] 0.487569464755766 0.8084326660839162 0.4188415534583285 1.0 0.4240044693715282 6 P31946,Q04917,P27348,P63104,P62258 5 +Dedicator of cytokinesis [IPR026791] 0.4236050248320161 0.7858312538970104 0.431966353810115 1.0 0.4369544179418715 2 Q14185 1 +Protein disulphide isomerase [IPR005792] 0.4360023378141476 0.7607078909292102 0.4468315605835795 1.0 0.4518173686855125 3 P07237,P30101 2 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.4216832261835199 0.678955577536745 0.4971660091663183 1.0 0.5023269019950345 3 P29992,P08754 2 +Plexin family [IPR031148] 0.4034472684779443 0.6672031858904185 0.5046423564137594 1.0 0.5096849010973712 2 Q9UIW2 1 +Translin family [IPR002848] 0.4031551270815031 0.6654977322322259 0.505732193544089 1.0 0.5105893986299908 2 Q99598 1 +Beta tubulin [IPR002453] 0.4562737642585474 0.641200452909962 0.5213924554181832 1.0 0.526197915836784 6 Q13885,Q9BVA1,Q9BUF5,P07437,P04350 5 +Plakophilin/Delta catenin [IPR028435] 0.3666374525270229 0.4571241873877371 0.647581786045287 1.0 0.6517981362416754 2 O60716 1 +Importin beta family [IPR040122] 0.3995556374189244 0.409802519371203 0.6819508179551486 1.0 0.686128158340785 5 Q8TEX9 1 +Mini-chromosome maintenance protein [IPR031327] 0.4021643755483941 0.3646941475005804 0.7153397277882134 1.0 0.7183465053983282 6 P33991,P33993,Q14566,P49736,P33992 5 +Glycoside hydrolase family 31 [IPR000322] 0.3494011101373001 0.36343745998345 0.7162781230227724 1.0 0.7190140975186577 2 P10253 1 +Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141] 0.3445353594389223 0.2655458539846175 0.7905889909099444 1.0 0.7923981190355964 3 Q9Y4Z0,P62314 2 +Proteasome B-type subunit [IPR023333] 0.3529060197007019 0.1444260438483739 0.8851640523835982 1.0 0.8865133878293049 7 P49721 1 +cAMP-dependent protein kinase regulatory subunit [IPR012198] 0.3026584867075583 0.1343903895973927 0.8930938806884834 1.0 0.8941145594092703 2 P10644 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..897f2d271855a0bfb777560ed8a9d82025741c4d --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [IPR039210]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3'5'-cyclic nucleotide phosphodiesterase [IPR023088]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ABL interactor 2 [IPR036993]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 15 [IPR042292]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 6-interacting protein 6 [IPR029383]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "Adenylyltransferase and sulfurtransferase MOCS3/Uba4 [IPR028885]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-(1,6)-fucosyltransferase [IPR015827]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit [IPR006111]", "ArfGAP ACAP1/2/3-like [IPR045258]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arrestin [IPR000698]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2 [IPR033093]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Atypical kinase COQ8B [IPR034638]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 13 [IPR040182]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BET1-like protein [IPR039897]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-adducin [IPR027773]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "Bis(5'-adenosyl)-triphosphatase ENPP4 [IPR029879]", "Brain acid soluble protein 1 [IPR008408]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 and ABL1 enzyme substrate 1/2 [IPR012388]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 7 [IPR037358]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calmodulin-regulated spectrin-associated protein [IPR032940]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-3/7 [IPR015471]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centlein [IPR038810]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein H [IPR040034]", "Centromere protein I [IPR012485]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Cerebellar degeneration-related protein 2 [IPR026079]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Ceroid-lipofuscinosis neuronal protein 6 [IPR029255]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Connexin [IPR000500]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine oxygenase/2-aminoethanethiol dioxygenase [IPR012864]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 10 [IPR015089]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 1 [IPR014807]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein COX14 [IPR029208]", "Cytochrome c oxidase biogenesis protein Cmc1-like [IPR013892]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit VIb [IPR003213]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase delta subunit 3 [IPR019038]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XRCC4 [IPR010585]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit RPC9 [IPR038846]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit RPB6 [IPR028363]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 1 [IPR030624]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase [IPR039488]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase UBR1-like [IPR039164]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "ETS family [IPR046328]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enolase-phosphatase E1 [IPR023943]", "Enolase-phosphatase E1, eukaryotes [IPR027511]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Erg28 [IPR005352]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 4 [IPR028478]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM91 [IPR039199]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "FeS cluster insertion protein [IPR016092]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv7/TAP26 [IPR013730]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GMP reductase [IPR005993]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRAM domain-containing protein 4 [IPR037847]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-glutamyltranspeptidase [IPR000101]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gap junction alpha-6 protein (Cx45) [IPR002265]", "Gasdermin-E [IPR042377]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucocorticoid receptor [IPR001409]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutaminyl-peptide cyclotransferase-like [IPR040234]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, ALG6/ALG8 [IPR004856]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycosyltransferase 61 [IPR007657]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "Guided entry of tail-anchored proteins factor CAMLG [IPR016719]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HIRA-interacting protein 3 [IPR037647]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Heat shock transcription factor family [IPR027725]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H3/CENP-A [IPR000164]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex subunit SAP30/SAP30-like [IPR024145]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin-interacting protein 1 [IPR030554]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "Hypoxia-inducible factor 1-alpha inhibitor [IPR027445]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Impact family [IPR023582]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor-interacting protein [IPR024797]", "Inositol 1,4,5-trisphosphate receptor-interacting protein family [IPR026250]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase [IPR033942]", "Inositol monophosphatase, lithium-sensitive [IPR020552]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 52 homolog [IPR039975]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isochorismatase domain-containing protein 2 [IPR040318]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LMBR1-like membrane protein [IPR006876]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Leo1-like protein [IPR007149]", "Lethal(2) giant larvae protein [IPR000664]", "Lethal(3)malignant brain tumour-like protein 2 [IPR038038]", "Leucine zipper protein 1 [IPR026734]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Liprin-beta-1 [IPR030437]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICAL-like protein [IPR028563]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate kinase [IPR006205]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial intermembrane space import and assembly protein 40 [IPR039289]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis MoaE [IPR003448]", "Molybdopterin synthase catalytic subunit, eukaryotes [IPR028888]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-plastoquinone oxidoreductase, chain 5 subgroup [IPR018393]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain 5-like [IPR003945]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neuroplastin [IPR027112]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar and spindle-associated protein 1 [IPR026756]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "ORC ubiquitin ligase 1 [IPR039209]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Opioid growth factor receptor [IPR039574]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PAX-interacting protein 1 [IPR037886]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic antigen Ma2 [IPR026525]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, Tysnd1 [IPR017345]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal/glyoxysomal leader peptide-processing protease [IPR039245]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphatidylserine lipase ABHD16A [IPR026604]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphofurin acidic cluster sorting protein 1 [IPR019381]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SLU7 [IPR039974]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein C10 [IPR026317]", "Protein CIP2A [IPR042510]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM210A/B-like [IPR045866]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein KTI12/L-seryl-tRNA(Sec) kinase [IPR013641]", "Protein Kti12 [IPR045106]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein NDRG1 [IPR030693]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SCAI [IPR022709]", "Protein SCAI, metazoan/viridiplantae [IPR016607]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1356, TMEM106 [IPR009790]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF2452 [IPR019534]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4661 [IPR029073]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-L-histidine N-pros-methyltransferase [IPR007884]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Prothymosin/parathymosin [IPR004931]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Purine-rich element-binding protein beta [IPR030499]", "Putative RNA methyltransferase [IPR003750]", "Putative RNA-binding protein 47 [IPR034442]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II subunit A [IPR006811]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, Rpb8 [IPR005570]", "RNA polymerase, subunit omega/Rpo6/RPB6 [IPR006110]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Ran-interacting Mog1 protein [IPR007681]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinoid X receptor/HNF4 [IPR000003]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27 [IPR001684]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12, bacterial-type [IPR005679]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21 [IPR001911]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SSNA1 family [IPR033362]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit [IPR037981]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 25 member 44 [IPR042164]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-30 [IPR028649]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindlin-1 [IPR029565]", "Spindlin/spermiogenesis-specific protein [IPR003671]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of fused [IPR007768]", "Suppressor of fused, eukaryotic [IPR016591]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-17 [IPR028676]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TIP41-like protein [IPR007303]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TNF receptor-associated factor 2 [IPR027133]", "TNF receptor-associated factor TRAF [IPR043211]", "TNF receptor-associated factor TRAF, metazoa [IPR012227]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "TSC-22 / Dip / Bun [IPR000580]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Teneurin-3/4 [IPR027691]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 16 [IPR040090]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor TFIIH subunit p52/Tfb2 [IPR004598]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, GA-binding, alpha subunit [IPR016312]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor TAFII31 [IPR003162]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 128 [IPR033579]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Type-1 angiotensin II receptor-associated protein [IPR009436]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0708 protein C6orf162 [IPR026686]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0489 [IPR024131]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vasodilator-stimulated phosphoprotein [IPR034367]", "Vasodilator-stimulated phosphoprotein/ENA/VASP-like [IPR017354]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps72/YL1 family [IPR008895]", "WASH complex subunit 3 [IPR019309]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "Xyloside xylosyltransferase 1 [IPR042465]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "Yos1-like [IPR013880]", "ZPR1 family [IPR040141]", "Zinc finger C2HC domain-containing protein [IPR026319]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter 9 [IPR040177]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 and DNA damage-regulated protein 1 [IPR030482]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-guanine transglycosylase [IPR004803]", "tRNAHis guanylyltransferase Thg1 [IPR007537]"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD16A", "ABHD6", "ABI2", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAP2", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AGTRAP", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG6", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANKLE2", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC1", "ARMC6", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG3", "ATG4B", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BET1", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf50", "C2orf49", "C5orf15", "C5orf22", "C5orf24", "C6orf47", "C8orf33", "CAB39", "CABLES1", "CAD", "CALD1", "CALR", "CALU", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP3", "CASP7", "CAST", "CBR1", "CBX2", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC59", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CD81", "CDC123", "CDC20", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDR2L", "CDS2", "CEBPZ", "CELF2", "CENPF", "CENPH", "CENPI", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1L", "CHD8", "CHERP", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMC2", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "CNTLN", "COA1", "COA3", "COA7", "COASY", "COG7", "COIL", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1C", "CORO7", "COTL1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRCP", "CRMP1", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIAPH2", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM210A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTB", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GALK1", "GALM", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GINS2", "GINS3", "GINS4", "GJC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMDS", "GMFB", "GMPR2", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPX8", "GRAMD4", "GRIPAP1", "GRPEL1", "GRSF1", "GSDME", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMPA1", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS1", "INTS14", "INTS3", "IPO4", "IPO5", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA1671", "KIAA2013", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L3MBTL2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMBRD1", "LMF2", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC47", "LSM12", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED17", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL16", "METTL3", "METTL9", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS2", "MOCS3", "MOGS", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MTX3", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA25", "NAA40", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "ND5", "NDC1", "NDRG1", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NES", "NHP2", "NIP7", "NIPBL", "NLN", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRM", "NRP1", "NSA2", "NSF", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACS1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PAWR", "PAXIP1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PECR", "PES1", "PEX11A", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLD2", "POLD3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CC", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTMA", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABL6", "RAC1", "RAC3", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFT1", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAI", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F1", "SLC35F2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMCHD1", "SMIM12", "SMIM4", "SMIM8", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPIN1", "SPOUT1", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUFU", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TECR", "TEDC1", "TEFM", "TENM3", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TLE3", "TM7SF2", "TM9SF1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM128", "TMEM14C", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMOD1", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TNPO2", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSR1", "TSTA3", "TTC19", "TTC26", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC17", "TXNDC9", "TXNRD1", "TXNRD2", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBR1", "UBR4", "UBR7", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCR11", "UQCRB", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UST", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VPS72", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDR11", "WDR12", "WDR18", "WDR33", "WDR41", "WDR46", "WDR73", "WDR74", "WDR82", "WDR91", "WFS1", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YEATS2", "YIF1A", "YIF1B", "YIPF4", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC2HC1A", "ZC3H14", "ZC3H7A", "ZC3H7B", "ZCCHC3", "ZCRB1", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZWILCH"], "leading_proteins": ["ABCB1", "ABCB7", "ACOX1", "ACP6", "ACSL6", "AK3", "AK4", "AKAP8L", "AP2S1", "AP3S1", "APOO", "ARF5", "ARFIP2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL5B", "ATAD3A", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP6V0A1", "ATP7B", "BCAP31", "BCKDK", "BCL2L13", "BSG", "CCNB2", "CHMP2A", "CHST14", "CISD1", "CLPTM1", "CLTA", "CNNM3", "COPS7A", "COX18", "COX7A2", "CPSF7", "CPT1A", "CRCP", "CTNND1", "CYFIP2", "CYP20A1", "DERL2", "DHRS1", "DHRS13", "DHRS7", "DOCK1", "DSCR3", "ERGIC2", "ERGIC3", "ERLIN1", "EWSR1", "EXOSC3", "FDPS", "FLOT2", "FUCA1", "FUS", "GAA", "GLT8D1", "GNA11", "GNAI3", "GNPAT", "HACD2", "HMGN1", 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0000000000000000000000000000000000000000..082e4aaae514d49cf193d181936f1d3388668b4c --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b6bc9355e735135d19b89b5bc81c06810438fd2a9851e00d0dedddd4c54bbf19 +size 335515 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2f4a771b991d5b9c268982c4a6621b83018a323f --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,15 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 19 23 3.6548726870070807 0.0002573096331059 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 3.295842498349804e-11 1.0 0.3076603852203092 1.5115233298475906e-08 8.760428776140621e-11 +EF-hand domain pair [IPR011992] 16 50 2.66808880977187 0.0076284090846288 13.3252427184466 49.37378640776699 0.9065364020670126 0.4404331516970506 4.9772339658485505 4.730718887980642 1.169914018421813 0.3730081256676846 0.0017923293804155 0.1241751068215353 0.3456909160626383 0.0346185484270672 0.0012262071663791 +Rhomboid-like superfamily [IPR035952] 5 6 2.520164612380236 0.0117299963588957 1.2749391727493915 2.81021897810219 0.761237662599581 0.3149837139908168 1.0670147015992797 1.2874058492416949 1.4147789572419682 0.3090632259014347 0.0010645583219727 1.0 1.0 1.0 9.569573614901708e-05 +P-type ATPase, A domain superfamily [IPR008250] 5 7 2.4645866369302003 0.0137171397286983 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.015895687074825 1.0 1.0 1.0 0.0034992238505004 +P-type ATPase, cytoplasmic domain N [IPR023299] 5 7 2.4645866369302003 0.0137171397286983 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.015895687074825 1.0 1.0 1.0 0.0034992238505004 +P-type ATPase, transmembrane domain superfamily [IPR023298] 5 7 2.4645866369302003 0.0137171397286983 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0185701326960502 1.0 1.0 1.0 0.0042957165481444 +SNARE [IPR010989] 6 8 2.3377125997931514 0.0194021621134568 2.4854368932038833 5.364077669902913 0.7966086592831925 0.3585374753437345 1.5079985943563208 1.7302199405020957 1.098385457365192 0.3157194502762394 0.000538728747922 1.0 0.1432798584585485 0.0561137872346343 6.703246650942136e-05 +MHC class I-like antigen recognition-like superfamily [IPR037055] 2 5 2.3187019058846614 0.0204112051210705 1.6286407766990292 3.3519417475728157 0.7088257141352072 0.3792248400111384 0.978137271268229 0.8617667089672962 1.1217132539816763 0.2987888107271844 0.1302665862694917 1.0 1.0 1.0 0.0277461310389573 +MHC classes I/II-like antigen recognition protein [IPR011162] 2 5 2.3187019058846614 0.0204112051210705 1.6286407766990292 3.3519417475728157 0.7088257141352072 0.3792248400111384 0.978137271268229 0.8617667089672962 1.1217132539816763 0.2987888107271844 0.195115846167058 1.0 1.0 1.0 0.0539281835546241 +Band 7/SPFH domain superfamily [IPR036013] 6 8 2.2883871227948505 0.0221149868835572 3.825242718446602 7.354368932038835 0.2848798017769268 0.3662852929750465 1.8717479731706237 0.7075565364256523 1.25010454777189 0.3076860385713043 0.0724548439670735 1.0 1.0 0.2175647207167039 0.0105668672564949 +LEM/LEM-like domain superfamily [IPR011015] 3 6 2.26306466927728 0.023631703091814 2.237864077669903 5.759708737864078 0.8787481060627674 0.3228260833428172 1.2758866328838632 0.4653299410110203 1.033781091163317 0.2887768895441466 5.804491071906608e-05 1.0 1.0 0.0082211090226218 7.614857799780336e-05 +Prefoldin [IPR009053] 1 5 2.1975922518651982 0.0279781758719959 2.0898058252427183 4.572815533980583 0.5922556317623713 0.4057599047024722 1.2124727846670618 1.0802906993483288 1.0235891073057894 0.3062773561417664 1.0 1.0 1.0 1.0 1.0 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 2 7 2.055408819997787 0.039839534311433 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0149736639257102 0.0561990347849709 0.0001778916397324 0.00262770885776 0.018020673376298 +Immunoglobulin-like domain superfamily [IPR036179] 6 18 1.9712573494413492 0.0486944471456021 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 0.6015480749562176 1.0 1.0 0.9413565249942258 0.3249357571378951 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1c17345d21815ee3cce8509b7647e3be2e540c8e --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 992, + "title": "Average number of proteins per term", + "value": 4.981854838709677 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..692b6acd08f8a668592fbeda836b61f0b08b37d2 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f16ccb57ee2a85760b6fcffb640c4d9dbb5e9bb6 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,107 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase-like, multi-helical [IPR016084] 0.9833479404031552 3.75262124839233 0.0001749951460705 0.1593756385718638 0.0035183919193606 2 P09601 1 +Cytochrome P450 superfamily [IPR036396] 0.978673678060182 3.7317165070512743 0.0001901794571534 0.1719452165603429 0.0035183919193606 2 Q6UW02 1 +Mitochondrial carrier domain superfamily [IPR023395] 0.7715638904561639 3.6548726870070807 0.0002573096331059 0.2253035478249271 0.0035950867048049 23 Q8TBP6,Q9BQT8,Q9HC21,P53007,O43808,Q9UJS0,P12236,P12235,Q9NZJ7,P05141,Q70HW3,Q96H78,Q02978,Q9Y6C9,Q6NUK1,Q9UBX3,Q9Y619,Q9H2D1,Q9BSK2 19 +MitoNEET, CDGSH iron-sulfur domain [IPR042216] 0.927841075080343 3.5007624425132664 0.0004639291914201 0.3689212012919028 0.004511938802831 2 Q9NZ45 1 +Cytochrome c oxidase, subunit VIIa superfamily [IPR036539] 0.91820040899796 3.4561917230198387 0.0005478654888346 0.4193641582246241 0.0046757261493324 2 P14406 1 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.9173239848086476 3.4521273432357096 0.0005561851669568 0.4241391205195919 0.0046757261493324 2 P50416 1 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9421390999415544 3.4205741737287134 0.0006248909251966 0.4621015874462217 0.005081080309796 3 O60637,O43657 2 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.8545135845749399 3.155242933873865 0.0016036451577177 0.7965007407126526 0.0079540799822798 2 Q15392 1 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.8545135845749399 3.155242933873865 0.0016036451577177 0.7965007407126526 0.0079540799822798 2 Q15392 1 +NAP-like superfamily [IPR037231] 0.8810637054354159 3.1394623977493294 0.0016925813541897 0.8137123445561458 0.0081589448491427 3 P55209,Q99733 2 +His-Me finger superfamily [IPR044925] 0.8442886356996839 3.1058321352453113 0.001897443974359 0.8480270037743193 0.0088793095786556 2 O94919 1 +DNA/RNA non-specific endonuclease superfamily [IPR044929] 0.8442886356996839 3.1058321352453113 0.001897443974359 0.8480270037743193 0.0088793095786556 2 O94919 1 +Regulatory factor, effector binding domain superfamily [IPR011256] 0.8270522933099721 3.0218274703585117 0.0025125370873573 0.9175508232846504 0.0107181859196717 2 Q9Y6I9 1 +Porin domain superfamily [IPR023614] 0.874341440214516 2.9696915069270933 0.0029809894130057 0.9482617476547242 0.0118760702718943 4 P45880,P21796 2 +BSD domain superfamily [IPR035925] 0.8121530820917409 2.9484799147158496 0.0031934089012508 0.958119316100386 0.0124718961812632 2 Q9NW68 1 +Bcl-2-like superfamily [IPR036834] 0.8464326556269964 2.838804153755908 0.004528294038161 0.9889161833737656 0.0150618664397656 4 Q9BXK5 1 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.817508037980845 2.835864489936857 0.0045701832644853 0.989369342253793 0.0150618664397656 3 P61289 1 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.817508037980845 2.835864489936857 0.0045701832644853 0.989369342253793 0.0150618664397656 3 P61289 1 +Proteasome activator superfamily [IPR036252] 0.817508037980845 2.835864489936857 0.0045701832644853 0.989369342253793 0.0150618664397656 3 P61289 1 +Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261] 0.8093034377602766 2.7958041721463385 0.0051770759248201 0.9941947884838002 0.0162825219804997 3 P16435 1 +Riboflavin synthase-like beta-barrel [IPR017938] 0.8093034377602766 2.7958041721463385 0.0051770759248201 0.9941947884838002 0.0162825219804997 3 P16435 1 +GOLD domain superfamily [IPR036598] 0.833147484239581 2.775729052073945 0.0055078087506328 0.995825866111169 0.0169681561510179 4 Q15363,Q9Y3A6 2 +C-type lectin fold [IPR016187] 0.7996433172009954 2.748374697608025 0.0059891521928236 0.9974177697757026 0.0179493624630849 3 Q8NBJ7 1 +START-like domain superfamily [IPR023393] 0.8216508015047015 2.7207368612115106 0.0065136588610186 0.9984703029760924 0.0188934198541826 4 O95433 1 +Tim10-like domain superfamily [IPR035427] 0.8196878169997122 2.7113090730032576 0.0067018124673312 0.998732330991847 0.0192701390365003 4 Q9Y5J9,Q9Y5J7 2 +Heavy metal-associated domain superfamily [IPR036163] 0.7607361963190291 2.689956559433465 0.0071461320735961 0.999186702569088 0.0198015726732049 2 P35670 1 +EF-hand domain pair [IPR011992] 0.4917275703317688 2.66808880977187 0.0076284090846288 0.999497740172553 0.0203099096615309 50 O95202,P60660,Q8NF37,Q9NWM8,O43852,Q9Y680,O75071,P80303,Q02818,Q14257,Q8IYU8,Q9BRK5,P41208,Q6NUK1,Q99584,O95302 16 +Peptidase S1, PA clan [IPR009003] 0.7828755113968354 2.665365792329847 0.0076904621048525 0.9995279495590622 0.0203438357547033 3 Q7KZN9,Q2T9J0 2 +Peptidase M41-like [IPR037219] 0.7508033888401977 2.639020619478786 0.0083145923555545 0.9997471101584708 0.0213308732050104 2 Q96TA2 1 +Cation efflux transmembrane domain superfamily [IPR027469] 0.7632963179427299 2.567326873148664 0.0102485952204971 0.9999635315071572 0.0249181530851303 3 Q8NEW0,Q6NXT4 2 +ARFGAP/RecO-like zinc finger [IPR037278] 0.7614275103500736 2.557905780450186 0.010530461951594 0.9999725078270189 0.0251716102553765 3 Q8N6H7 1 +ArfGAP domain superfamily [IPR038508] 0.7614275103500736 2.557905780450186 0.010530461951594 0.9999725078270189 0.0251716102553765 3 Q8N6H7 1 +Rhomboid-like superfamily [IPR035952] 0.8189529102076725 2.5201646123802357 0.0117299963588957 0.9999917470582668 0.0271872812804311 6 Q6NTF9,Q9BUN8,Q9GZP9,Q9H300,Q8NBM4 5 +P-type ATPase, A domain superfamily [IPR008250] 0.7998479057890941 2.4645866369302003 0.0137171397286983 0.9999988793394458 0.030721134627741 7 P35670,Q9NQ11,P16615,Q9HD20,P05023 5 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7998479057890941 2.4645866369302003 0.0137171397286983 0.9999988793394458 0.030721134627741 7 P35670,Q9NQ11,P16615,Q9HD20,P05023 5 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7998479057890941 2.4645866369302003 0.0137171397286983 0.9999988793394458 0.030721134627741 7 P35670,Q9NQ11,P16615,Q9HD20,P05023 5 +MRG, C-terminal domain superfamily [IPR038217] 0.7110721589249286 2.4319456651487985 0.0150179600123658 0.9999996973886474 0.0326706498514626 2 Q9UBU8 1 +Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702] 0.7099035933391762 2.425773325043903 0.0152758080777506 0.9999997666055132 0.0330143825994087 2 P54709 1 +Lamin tail domain superfamily [IPR036415] 0.7291057860900058 2.393189268899522 0.0167026224548618 0.9999999446137638 0.034805078928252 3 Q03252,P02545 2 +Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438] 0.7288146318731754 2.3916901148719307 0.0167709956932504 0.999999948305554 0.034805078928252 3 Q53H12 1 +NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064] 0.7288146318731754 2.3916901148719307 0.0167709956932504 0.999999948305554 0.034805078928252 3 Q53H12 1 +SNARE [IPR010989] 0.7665529106394039 2.3377125997931514 0.0194021621134568 0.9999999963775376 0.0385051182879583 8 P56962,O15400,O43752,O60499,Q13190,Q9UEU0 6 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.7148707018584342 2.319567793504607 0.0203642697914054 0.9999999986319568 0.039936716923278 3 P52888 1 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.7400252446368545 2.319027542652706 0.0203935429625596 0.9999999986719148 0.039936716923278 4 P52888,P42892 2 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.7583602068064087 2.3187019058846614 0.0204112051210705 0.9999999986954572 0.039936716923278 5 P30511,P55899 2 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.7583602068064087 2.3187019058846614 0.0204112051210705 0.9999999986954572 0.039936716923278 5 P30511,P55899 2 +EB1, C-terminal domain superfamily [IPR036133] 0.6871165644171797 2.304462425716001 0.0211966992367089 0.9999999994113437 0.0409885490113358 2 Q15555 1 +Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784] 0.7115721800116885 2.302413400831081 0.0213118699606522 0.9999999994761988 0.0410512135941107 3 O14874,Q15118 2 +Band 7/SPFH domain superfamily [IPR036013] 0.7566929700989043 2.2883871227948505 0.0221149868835572 0.999999999768 0.0422698785905372 8 P35232,O75477,Q99623,O94905,P27105,Q9UJZ1 6 +LEM/LEM-like domain superfamily [IPR011015] 0.7655424193522884 2.2630646692772793 0.023631703091814 0.9999999999502538 0.0445979403978429 6 P42167,P50402,Q9Y2U8 3 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.7227654013437161 2.231482593181476 0.0256491792806448 0.999999999993608 0.0475588520493451 4 O43399 1 +Prefoldin [IPR009053] 0.7340690984110319 2.1975922518651982 0.0279781758719959 0.9999999999994048 0.0509740922166865 5 Q99471 1 +Adenylate kinase, active site lid domain superfamily [IPR036193] 0.6672509494595459 2.1972174543522764 0.0280049196150142 0.9999999999994208 0.0509740922166865 2 Q9UIJ7 1 +Ricin B-like lectins [IPR035992] 0.7053475451677049 2.14219636839683 0.0321776836295684 0.999999999999992 0.0565562402806169 4 Q10472,Q9UBG0 2 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.7173555372496301 2.055408819997787 0.039839534311433 1.0 0.0676726336248999 7 O15173,O43169 2 +SCP2 sterol-binding domain superfamily [IPR036527] 0.6630625365283415 2.0459724621963287 0.0407590801050363 1.0 0.0689983062528943 3 P22307,Q6YN16 2 +Immunoglobulin-like domain superfamily [IPR036179] 0.5795715210834101 1.9712573494413497 0.0486944471456021 1.0 0.0784170317669436 18 Q08722,P30511,P35613,P55899,Q9Y639,P78310 6 +Helix hairpin bin domain superfamily [IPR029012] 0.6228454572012925 1.9524504385477317 0.0508847496927529 1.0 0.080893704639761 2 Q9H9H4 1 +Carboxypeptidase-like, regulatory domain superfamily [IPR008969] 0.5904177621969129 1.769350989365032 0.0768353191683246 1.0 0.1112710023576321 2 Q9P273 1 +Histidine phosphatase superfamily [IPR029033] 0.6615940456436826 1.739396626155707 0.0819650212916105 1.0 0.1181213114787869 6 Q9NPH0 1 +Kringle-like fold [IPR013806] 0.5987848113755977 1.6942686946997187 0.0902142364500508 1.0 0.1258586482873358 3 Q9UBV2 1 +Fibronectin type II domain superfamily [IPR036943] 0.5987848113755977 1.6942686946997187 0.0902142364500508 1.0 0.1258586482873358 3 Q9UBV2 1 +Rpb4/RPC9 superfamily [IPR038324] 0.564125036517685 1.6183080712352411 0.105596222136336 1.0 0.1421322284385961 2 O75575 1 +Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695] 0.5617879053461992 1.6047755608395564 0.1085432061786821 1.0 0.145310203143391 2 Q5T160 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4948275048011632 1.5999670952772012 0.1096058832299076 1.0 0.1455542652798773 21 Q8NBM8,Q9UHG3,Q14534,Q96CU9,Q8NCN5 5 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.5960659427985142 1.4767292060524282 0.1397482399918117 1.0 0.176599049773092 5 A1L0T0,Q13423 2 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.4674219641401619 1.396819047297286 0.1624679929967256 1.0 0.2002090050344743 21 Q9Y673,Q8NBI6,Q4G148,O60762,Q9NR50,Q10471,Q68CQ7,Q10472,Q93063 9 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.5782101261361843 1.3461898545822435 0.1782412961315134 1.0 0.2156284948322698 8 P28288,P08183,Q03519,Q03518,O75027,P33527 6 +NET domain superfamily [IPR038336] 0.5353594389246029 1.3351430794237082 0.1818295222334978 1.0 0.2194341679508878 3 Q15059,O60885 2 +Chloramphenicol acetyltransferase-like domain superfamily [IPR023213] 0.5795610811582264 1.305912630460571 0.1915822708611827 1.0 0.2298060612990245 6 P50416,P23786 2 +PapD-like superfamily [IPR008962] 0.5093512565750862 1.1852292471169157 0.2359268191221712 1.0 0.2756647874784381 3 Q8NHP6,O95292 2 +Thioredoxin-like superfamily [IPR036249] 0.34019660953248 1.176955758283495 0.239213165125157 1.0 0.2791758350637126 53 O75880,Q9H1E5,Q9Y320,Q9H7Z7,Q96J42,Q8TED1,Q96CS3,Q9H3N1,Q6ZRP7,O43819,Q96JJ7,Q9H0U3 12 +LDL receptor-like superfamily [IPR036055] 0.4881682734443495 1.1711192480532686 0.241550847989554 1.0 0.2812423018845512 2 Q07954 1 +Beta-lactamase/transpeptidase-like [IPR012338] 0.4776511831726527 1.1083250443222428 0.2677214632600231 1.0 0.3077400829130277 2 O94925 1 +ANL, N-terminal domain [IPR042099] 0.5345737265795973 1.082638749622151 0.2789688006405559 1.0 0.3188214864463496 7 Q9UKU0,O14975 2 +Ribosomal protein S10 domain superfamily [IPR036838] 0.472392638036811 1.0768933189401306 0.2815279282069596 1.0 0.3213759548691645 2 Q96GC5 1 +Immunoglobulin-like fold [IPR013783] 0.3689400398170931 1.062798072691405 0.2878735337489617 1.0 0.3282420062976667 35 Q8IZA0,Q8NAT1,Q08722,P30511,P35613,Q14118,P55899,Q9Y639,P78310 9 +Translation initiation factor IF-2, domain 3 superfamily [IPR036925] 0.4642126789366246 1.0279756629192238 0.3039612758651659 1.0 0.3438193679113394 2 P46199 1 +Translation elongation factor EF1B/ribosomal protein S6 [IPR014717] 0.4627519719544249 1.0192392273800228 0.3080894077306602 1.0 0.3476958958689589 2 P29692 1 +Translation elongation factor eEF-1beta-like superfamily [IPR036219] 0.4627519719544249 1.0192392273800228 0.3080894077306602 1.0 0.3476958958689589 2 P29692 1 +Ribosomal protein S7 domain superfamily [IPR036823] 0.4612912649722446 1.0105029044014422 0.3122544086308703 1.0 0.3519958788202538 2 Q9Y2R9 1 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.4121830889214818 0.8170720747275777 0.4138872404086005 1.0 0.4556893923255623 18 Q9H7Z7,Q13505,O75431 3 +Alpha/beta knot methyltransferases [IPR029028] 0.4447691408533065 0.8111119573264604 0.4173013796943867 1.0 0.4584307515579531 3 Q13395,Q92979 2 +tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026] 0.4447691408533065 0.8111119573264604 0.4173013796943867 1.0 0.4584307515579531 3 Q13395,Q92979 2 +14-3-3 domain superfamily [IPR036815] 0.487569464755766 0.8084326660839162 0.4188415534583285 1.0 0.4596137400781658 6 P31946,Q04917,P27348,P63104,P62258 5 +HAD-like superfamily [IPR036412] 0.3719608170308814 0.7881532253028676 0.4306070852413288 1.0 0.4708907944831144 23 Q9HD20,P35670,Q9UHY7,Q3ZCQ8,P20020,Q9NQ11,P16615,P98194,Q969T7,P05023,Q9H857 11 +HAD superfamily [IPR023214] 0.3719608170308814 0.7881532253028676 0.4306070852413288 1.0 0.4708907944831144 23 Q9HD20,P35670,Q9UHY7,Q3ZCQ8,P20020,Q9NQ11,P16615,P98194,Q969T7,P05023,Q9H857 11 +Dedicator of cytokinesis, C-terminal, lobe C [IPR043162] 0.4236050248320161 0.7858312538970104 0.431966353810115 1.0 0.4708907944831144 2 Q14185 1 +Dedicator of cytokinesis, C-terminal, lobe A [IPR043161] 0.4236050248320161 0.7858312538970104 0.431966353810115 1.0 0.4708907944831144 2 Q14185 1 +Queuine tRNA-ribosyltransferase-like [IPR036511] 0.4145486415425201 0.7323246485100443 0.4639704382651466 1.0 0.5041168398236862 2 Q9H974 1 +G protein alpha subunit, helical insertion [IPR011025] 0.4216832261835199 0.678955577536745 0.4971660091663183 1.0 0.5378284417589835 3 P29992,P08754 2 +Sema domain superfamily [IPR036352] 0.4034472684779443 0.6672031858904185 0.5046423564137594 1.0 0.543182814051213 2 Q9UIW2 1 +Translin, N-terminal [IPR016068] 0.4031551270815031 0.6654977322322259 0.505732193544089 1.0 0.543182814051213 2 Q99598 1 +Translin, C-terminal [IPR016069] 0.4031551270815031 0.6654977322322259 0.505732193544089 1.0 0.543182814051213 2 Q99598 1 +Translin superfamily [IPR036081] 0.4031551270815031 0.6654977322322259 0.505732193544089 1.0 0.543182814051213 2 Q99598 1 +L27 domain superfamily [IPR036892] 0.4340836012861782 0.6563443220726881 0.5116026059274819 1.0 0.5481774033301294 4 O14936,Q5T2T1,Q9NZW5 3 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.4511184618882239 0.6267729402503609 0.5308080835852036 1.0 0.5668047566378062 7 P22695 1 +Beta-grasp domain superfamily [IPR012675] 0.4353535451226082 0.5557683865076626 0.5783691995874549 1.0 0.6129724850328582 8 P21912 1 +NTF2-like domain superfamily [IPR032710] 0.4364643252269946 0.5489055366094975 0.5830702783981674 1.0 0.6172953214204717 7 O43615 1 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.3831092928112229 0.4646332421354289 0.6421941225929269 1.0 0.6727102107837206 3 Q9UEY8,P35611 2 +p53-like tetramerisation domain superfamily [IPR036674] 0.3651767455448367 0.4490427836719438 0.6534007937339945 1.0 0.68372741285245 2 Q13043 1 +Cyclin-like superfamily [IPR036915] 0.3531131248173014 0.2384165219671807 0.8115580541698519 1.0 0.8334012316112765 4 P14635,Q00403,O95067 3 +AH/BAR domain superfamily [IPR027267] 0.3221059027579371 0.1876250146378653 0.8511706156367487 1.0 0.8722740193302218 17 Q15057,Q5VWJ9,O60749,Q9UNH7,Q9Y371 5 +HotDog domain superfamily [IPR029069] 0.3627677547859146 0.1829292796313169 0.8548535086964366 1.0 0.8751441492537307 6 Q8WUY1 1 +Putative DNA-binding domain superfamily [IPR009061] 0.2991527899503279 0.1191345615772399 0.9051687495409536 1.0 0.9256983500460064 2 Q6PML9 1 +PUA domain superfamily [IPR036974] 0.284253578732101 0.0579694617565273 0.9537729535936904 1.0 0.9713991478079476 2 Q9Y221 1 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e8d95bfeb4574d3fe81852c4616daf9696472a06 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily [IPR036971]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-dystroglycan domain 2 [IPR027468]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin, N-terminal [IPR014753]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CKK domain superfamily [IPR038209]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Connexin, N-terminal domain superfamily [IPR038359]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit VIb superfamily [IPR036549]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase delta subunit 3 superfamily [IPR041913]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Focal adhesion kinase, targeting (FAT) domain superfamily [IPR036137]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-glutamyltranspeptidase, large subunit, C-terminal domain [IPR043138]", "Gamma-glutamyltranspeptidase, small subunit [IPR043137]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycolipid transfer protein superfamily [IPR036497]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "HesB-like domain superfamily [IPR035903]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hypoxia-inducible factor 1-alpha inhibitor, domain II [IPR027452]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Impact, N-terminal domain superfamily [IPR036956]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "Mir domain superfamily [IPR036300]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "Moesin tail domain superfamily [IPR008954]", "Mog1/PsbP, alpha/beta/alpha sandwich [IPR016123]", "Molybdopterin biosynthesis MoaE subunit superfamily [IPR036563]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAS domain superfamily [IPR035965]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRC-barrel-like superfamily [IPR011033]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPB6/omega subunit-like superfamily [IPR036161]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RUN domain superfamily [IPR037213]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21 superfamily [IPR038380]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAP30, C-terminal domain superfamily [IPR038291]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single alpha-helix domain superfamily [IPR029027]", "Single hybrid motif [IPR011053]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spindlin/spermiogenesis-specific domain superfamily [IPR042567]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Suppressor of fused, C-terminal domain superfamily [IPR038489]", "Suppressor of fused, N-terminal [IPR037181]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPA domain superfamily [IPR037129]", "XPC-binding domain superfamily [IPR036353]", "XRCC4, N-terminal domain superfamily [IPR009089]", "XRCC4-like, N-terminal domain superfamily [IPR038051]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "tRNAHis guanylyltransferase Thg1 superfamily [IPR038469]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD13", "ABHD16A", "ABHD6", "ABI2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG13", "ALG5", "ALKBH5", "ALYREF", "AMFR", "ANAPC1", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD46", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL5B", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATXN10", "ATXN2", "AURKA", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCKDHA", "BCKDHB", "BCKDK", "BCL2L12", "BCL2L13", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "CAB39", "CABLES1", "CACYBP", "CAD", "CADM1", "CALR", "CALU", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "COQ8B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRCP", "CRK", "CRKL", "CRMP1", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAC2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTB", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GIGYF2", "GINS2", "GINS3", "GINS4", "GJC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLPH3", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPN1", "GPS1", "GPX8", "GRAMD4", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IBTK", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS4", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRS4", "ISCA2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KTI12", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRWD1", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED25", "MEPCE", "METAP2", "METTL13", "METTL16", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOB4", "MOCS2", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCBP1", "NCBP3", "NCDN", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDRG1", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF1", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NENF", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGL", "PIK3C2A", "PIK3R2", "PIK3R4", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "S100A13", "SAAL1", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMS", "SMU1", "SMYD3", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX17", "STX4", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "THADA", "THEM6", "THG1L", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TXNRD2", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCR11", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URGCP", "UROD", "USO1", "USP10", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UST", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WNK1", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF280C", "ZNF281", "ZNF512", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD3", "ACAP2", "ACP6", "ACSL6", "ADD1", "ADD3", "AGK", "AHSA1", "AK3", "ALG5", "ARFGAP2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP7B", "BCKDK", "BCL2L13", "BRD3", "BRD4", "BSDC1", "BSG", "CALU", "CASK", "CCNB1", "CCNB2", "CD47", "CETN2", "CISD1", "COX15", "COX7A2", "CPT1A", "CPT2", "CRCP", "CXADR", "CYB5B", "CYP20A1", "DAG1", "DERL1", "DERL2", "DHCR24", "DOCK1", "DPM1", "ECE1", "EEF1D", "EFCAB14", "EIF2B3", "EMD", "EMG1", "ENDOD1", "ENOPH1", "ERLIN1", "ERLIN2", "EXT2", "FAF2", "FCGRT", "FKBP14", "FKBP7", "FKBP9", "FOXRED1", "GALNT1", "GALNT2", "GLS", "GLT8D1", "GNA11", "GNAI3", "GPX8", "GTF2B", "GXYLT1", "HLA-F", "HMOX1", "HSDL2", "ILVBL", "KIAA0319L", "LEMD3", "LETM1", "LMNA", "LMNB2", "LPCAT1", "LRP1", "MAGT1", "MAPRE2", "MICU2", "MORF4L1", "MOSPD2", "MPP6", "MPP7", "MRC2", "MRPL48", "MRPS7", "MTCH1", "MTCH2", "MTIF2", "MTX1", "MTX2", "MYL6", "NAP1L1", "NAP1L4", "NIP7", "NNT", "NPTN", "NT5C3B", "NT5DC2", "NUCB1", "NUCB2", "PARL", "PCYOX1", "PCYOX1L", "PDK1", "PDPR", "PFDN5", "PGRMC2", "PHB", "PHB2", "PLXNA1", "POMGNT2", "POR", "PSME3", "PTGES2", "QSOX2", "QTRT2", "RARS2", "RCN2", "RHBDD2", "S100A13", "SCO1", "SCO2", "SCP2", "SDF4", "SDHB", "SEL1L", "SH3GLB1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC30A6", "SLC30A7", "SLC30A9", "SNX2", "SNX30", "SNX6", "SQLE", "STK4", "STOM", "STOML2", "STX10", "STX17", "STX5", "STX6", "STX7", "SUMF2", "TAP1", "TAP2", "TARBP1", "TENM3", "TEX264", "THEM6", "THOP1", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TMED2", "TMED5", "TMPO", "TMX1", "TMX2", "TMX3", "TMX4", "TPD52L2", "TSNAX", "TSPAN3", "TSPAN6", "TXNDC15", "TYSND1", "UBAC2", "UQCRC2", "VAPB", "VDAC1", "VDAC2", "VPS37B", "VTI1B", "XXYLT1", "YME1L1", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6b2b1d3e31851c6905a093a9239a9bf9fdb4ccf5 --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "P-type ATPase, phosphorylation site [IPR018303]"} \ No newline at end of file diff --git a/interpro_ptm/advanced/plot_0.png b/interpro_ptm/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..06531e00daa81f8bbae0a95b250acc5c694676f1 --- /dev/null +++ b/interpro_ptm/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ca40ab09356aff4e4ffda123d80f767112f2f30dc2b946851773bbddb5ad9fa7 +size 167581 diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6b2b1d3e31851c6905a093a9239a9bf9fdb4ccf5 --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "P-type ATPase, phosphorylation site [IPR018303]"} \ No newline at end of file diff --git a/interpro_ptm/basic/plot_0.png b/interpro_ptm/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6c7682ffa817d6b68cbded09685771c35b0fa499 --- /dev/null +++ b/interpro_ptm/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90d1f7c6aef41fa56cbccc64a3cb81be9cbad8e486efba2fb6dc45ccfa68e38a +size 143255 diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..35e2d985be8968e42c624b6b9dcc17f9c20153c0 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5a8d9e645d4d6a63e4da1d77b2d2616cb278e3fd96b5580f29248b7547f1824 +size 76704 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d48fa936db049a0be08e3557a6395d2f07dc5bb6 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +P-type ATPase, phosphorylation site [IPR018303] 5 7 2.4645866369302003 0.0137171397286983 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.015895687074825 1.0 1.0 1.0 0.0034992238505004 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b513c6678629ebfb3f1abed74e89bcfe9f25fc2f --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.75 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..48ac3a6036fd345c930233226f42e8dc991eec70 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fb8ca7f68e0475ff5a21e5730a9354f67b8e7f36 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7998479057890941 2.4645866369302003 0.0137171397286983 0.0537498880404014 0.0182895196382644 7 P35670,Q9NQ11,P16615,Q9HD20,P05023 5 +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 0.4095822378031104 0.7031196193974515 0.4819812064027093 0.927991781829286 0.4819812064027093 2 Q07954 1 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6378e5832370357da697d10cba03f70bbd0ff034 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP7B", "EIF5A", "FASN", "LRP1", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP7B", "LRP1"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7bf9a3f8b6202acf1996448fd9981bed20f4b8b1 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:abc308e6991feea9aa91e5b4b43936741575fe7a596d79badb9f06f21d7da976 +size 185139 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ffb96ab3129254fe820b4bfdf163bc2d6c2317d3 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:add5e5ec5ad10eeb4d665cbc82c23369a1d4e7c4cf26d276fab0d424faf10e8e +size 150785 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..88437008db87f9aac9f673ef3c30972bf789737b --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c8118bdf33364d5db8cad64ca0b9d5d62d778ec8e8d5d9ea23df098a890b968 +size 95183 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ac56d6129bd1f62c783599cbadc58229287727ed --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 19 23 3.6548726870070807 0.0002573096331059 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 3.295842498349804e-11 1.0 0.3076603852203092 1.5115233298475906e-08 8.760428776140621e-11 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a3478f8a7054dcceb2f855b88963ba1da4b68988 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 79, + "title": "Average number of proteins per term", + "value": 5.455696202531645 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..90cd0c3bd847eaa4e4ad7ff14d35ad693d912246 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..90d572d4e0daef6f036417263336a46d1598efa7 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7715638904561639 3.6548726870070807 0.0002573096331059 0.020124814035966 0.0018479510013976 23 Q8TBP6,Q9BQT8,Q9HC21,P53007,O43808,Q9UJS0,P12236,P12235,Q9NZJ7,P05141,Q70HW3,Q96H78,Q02978,Q9Y6C9,Q6NUK1,Q9UBX3,Q9Y619,Q9H2D1,Q9BSK2 19 +Sel1-like repeat [IPR006597] 0.8007595676307435 2.8919234715176385 0.0038289120032326 0.2614486326585503 0.0090715596549727 2 Q9UBV2 1 +Kinesin light chain repeat [IPR015792] 0.7331969608416147 2.414225495441073 0.0157686999594912 0.7151103977587193 0.0283119840181774 3 Q9NSK0,Q07866 2 +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 0.4881682734443495 1.1711192480532686 0.241550847989554 0.9999999996732684 0.2891290453208298 2 Q07954 1 +Plexin repeat [IPR002165] 0.4034472684779443 0.6672031858904185 0.5046423564137594 1.0 0.5736735227231835 2 Q9UIW2 1 +HEAT repeat [IPR000357] 0.3301966027055771 0.0528416841810943 0.9578580487026398 1.0 0.9701382800962634 6 Q8TEX9 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5eff41b8fcf5e98082d58ad630a0e4a2b3d08569 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "Opioid growth factor receptor repeat [IPR006770]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "YD repeat [IPR006530]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACAP2", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD46", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ARVCF", "ASPH", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EHMT1", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPB", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HUWE1", "IBTK", "IFIT5", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGA6", "JUP", "KAT7", "KDELC2", "KDM2A", "KIAA1468", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "L3MBTL2", "LARP1", "LASP1", "LLGL1", "LRBA", "LRP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MKI67", "MRPS27", "MTCH1", "MTCH2", "MTPN", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGFR", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "PLXNA1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP5", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC13", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TENM3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTC7B", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "XAB2", "XIAP", "XPO1", "YTHDC2", "ZC3H7B"], "leading_proteins": ["IPO4", "KLC1", "KLC4", "LRP1", "MTCH1", "MTCH2", "PLXNA1", "SEL1L", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", 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3.744653334620665e-29 +Membrane organization 93 242 5.264958084334567 1.402213459844062e-07 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 7.907936168435306e-19 0.0399875865627003 1.0054448242037093e-05 1.4652068316223453e-12 2.0122705267733596e-22 +Transmembrane transport 118 231 5.123137224558237 3.004934916698419e-07 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 5.5064439454436505e-14 0.0112371844547471 0.0001285362081583 1.0551333991310514e-08 2.7667060338549517e-15 +Mitochondrial transport 46 94 4.824277749694426 1.405114986104284e-06 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 1.1654577516719656e-17 0.0012471197288945 3.3947960014797515e-05 6.777646444506297e-10 2.860659714554489e-18 +Mitochondrial transmembrane transport 35 55 4.767310412992952 1.8670154222633075e-06 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 2.375162617325615e-16 0.0007162824744306 0.00132313066272 1.5364561479723256e-10 1.2621848738625545e-17 +Mitochondrial respiratory chain complex assembly 31 51 4.653306966653274 3.2665339866344567e-06 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 8.671044201411846e-12 0.0094231818265578 2.5571366815777788e-05 4.040189993563273e-09 4.8590796519201844e-12 +Mitochondrial membrane organization 30 50 4.612549672939855 3.977594474902091e-06 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 5.06872469904288e-13 0.0108990791164893 3.621358703023616e-05 8.652170791034841e-09 3.9124180331152e-14 +Endoplasmic reticulum organization 26 51 4.587594658341931 4.48382142503867e-06 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 1.3154362683202721e-14 0.0057337308923017 7.766181213459843e-06 2.5686963237734515e-11 6.1153724430474905e-15 +Ion transmembrane transport 71 169 4.542042833290425 5.5711717610318345e-06 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 5.617553528297762e-10 0.067145446295508 0.0043157081841909 5.528041558443803e-06 9.313946482757943e-11 +Anion transport 39 73 4.423759303051307 9.699808465768456e-06 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 2.408933036402162e-08 0.249749131632643 0.1263572186990123 3.590725155705025e-07 1.0830216818577309e-07 +Nitrogen compound transport 175 621 4.405586523798354 1.0549803044712648e-05 134.15533980582524 569.4538834951456 0.9072063241864304 0.6401677607980054 37.1767641393764 58.81145048559368 1.470232145086419 0.4303798393104362 5.413104720038799e-11 0.3504469154995983 0.0056726975994785 1.7574588427473832e-06 1.9876806696940138e-13 +Ion transport 87 220 4.390960860171912 1.1285085514067816e-05 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 1.878172635831303e-09 0.186058060279213 0.0073648817034719 3.550875600699599e-06 1.1033946530441084e-10 +Protein localization to mitochondrion 33 70 4.360736438820201 1.2962542789818343e-05 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 1.71468129270366e-13 0.0149620345130709 0.0005873272870129 3.056123406945332e-07 1.6588443219449124e-14 +Organic anion transport 38 49 4.273797278459606 1.921717708674997e-05 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 2.567209427470568e-05 1.0 0.7535657767064036 0.0001914371667194 6.5669043441522e-05 +Protein targeting to mitochondrion 27 56 4.240420766242433 2.2310117880453006e-05 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 4.060580235395415e-12 0.0085976741283889 0.0001940435749139 8.327521080072054e-06 2.7264364581928305e-13 +Oxidative phosphorylation 36 70 4.192359754203861 2.760677488700125e-05 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 2.738498104528603e-09 0.0002518558292813 1.635920485548201e-08 4.64363330137137e-10 6.381211160071019e-11 +Endomembrane system organization 61 188 4.189177645176977 2.7996717366196577e-05 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 4.356715771524575e-11 0.2845607441622844 0.0324797110781788 7.303250487718589e-06 3.5855611644408826e-13 +Protein targeting 48 122 4.111421124927464 3.9323121307388575e-05 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 4.042114331336676e-11 0.0068519784881021 0.0001428671553367 1.072612085286703e-05 4.898880860340347e-12 +Establishment of protein localization 161 565 4.103312325651653 4.0727684697872135e-05 118.26941747572816 516.7257281553398 0.6520395559374618 0.679532677582667 31.472560658738065 53.21298128179791 1.2523101724416292 0.4083128036600569 4.136998173435624e-09 0.0698485682301616 0.0068983234592493 0.0001028143360259 5.092627643692284e-12 +Cation transmembrane transport 62 132 4.100031288317372 4.130942848923347e-05 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 5.985892265079772e-06 0.104162521549783 0.027258683154983 0.0196779360589525 7.611146263907472e-07 +Membrane lipid metabolic process 24 44 4.085705852963486 4.394302049015586e-05 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 3.867383232078757e-07 0.4409382257745535 0.3210427924142759 0.0001527751802754 1.1479599106739243e-06 +Inorganic ion transmembrane transport 48 122 4.013551805079679 5.981186784986825e-05 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 5.084822915728067e-06 0.0811245339020894 0.0169622408584308 0.003976953785359 1.4096699446978622e-06 +Protein insertion into membrane 21 33 3.97156521099131 7.140194915167264e-05 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 3.263758322142404e-12 0.0248381956323572 0.0001225386178253 3.097193227533339e-07 1.0399804539190314e-11 +Intracellular transport 164 591 3.9534818798479647 7.702209933735382e-05 120.90291262135922 544.3956310679612 0.5500812282996078 0.6924011803517542 31.43517433849213 53.582766758854405 1.193070641867047 0.396756529943003 5.928058949603072e-11 0.142605565580476 0.0074806282710218 4.929624173631373e-08 1.1738896088262022e-13 +Anion transmembrane transport 28 43 3.9516328960097296 7.76197476932694e-05 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 2.547171438438981e-06 0.1008495778431075 0.0929934383816013 1.6167865230585396e-05 6.692467974427642e-06 +Inner mitochondrial membrane organization 18 24 3.9390506401858585 8.180466408092002e-05 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 1.3073686934397192e-12 0.0135379522122687 2.5288360625722612e-05 1.1377558719421884e-08 2.2794732059696513e-13 +Membrane lipid biosynthetic process 17 27 3.8999437748476735 9.621502935286408e-05 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 1.6348538528088747e-05 0.3274019772455256 0.5484830827387088 0.0036501932708164 3.521476861973183e-05 +Establishment of protein localization to membrane 42 96 3.895844951668785 9.785697766417913e-05 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 9.83746831242556e-09 0.0163421355973242 0.0034462087166857 3.515266077408032e-05 3.304886902156065e-09 +Protein transmembrane transport 14 26 3.8631262294010544 0.0001119451240982 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 5.979942826639593e-08 0.0020640692536444 0.0001474440444245 4.529400865538198e-07 1.8003214599323024e-08 +Nadh dehydrogenase complex assembly 21 37 3.799571119984112 0.0001449467124183 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 2.1193077235140897e-08 0.0305319028295214 0.0021465314893355 9.212437581942882e-07 6.838915987879926e-09 +Endoplasmic reticulum to golgi vesicle mediated transport 29 75 3.7828069618724207 0.0001550696764174 17.32766990291262 65.39077669902913 0.808881464821498 0.4942452999677598 7.539018980743236 6.620812461410292 1.284359804176963 0.3933269611423161 7.439343004732842e-09 0.1054077938723316 0.0049403667773054 1.0519174334956696e-07 1.6794200972207308e-10 +Respiratory electron transport chain 29 60 3.758527189520526 0.0001709164680172 15.4126213592233 50.33495145631068 0.497076868891423 0.4388579749555677 7.129498131980449 4.223655269147207 1.4894225458303931 0.3736358875877055 1.2087396833478208e-06 0.0108990791164893 3.611186852814194e-06 1.9346727124503963e-05 2.500139583623858e-08 +Proton transmembrane transport 19 47 3.7545269471040736 0.0001736691613449 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 1.723386562098375e-07 0.0748187401998431 0.0002783591093982 8.796079501648624e-05 1.7109957662803998e-08 +Organelle fusion 26 55 3.665988643978325 0.0002463848589024 14.74514563106796 45.383495145631066 0.6448767361523368 0.5292766623385164 6.293825046556003 6.576179389035289 1.1045479661060835 0.3741954647136961 0.0002260197380112 0.4299325182794405 0.3068592732118059 0.0225148091657114 3.069111791510144e-08 +Golgi vesicle transport 51 147 3.657555614478184 0.0002546320214715 32.30825242718446 130.0995145631068 0.5186556770214802 0.6391424830765352 11.558195085956042 14.851278907933963 1.0581936514451007 0.3745819971007444 2.8458615143735628e-08 0.3617750709606537 0.0408976472683376 6.984962121931155e-05 3.3143607861265584e-10 +Organic acid transport 33 48 3.5985309460054675 0.0003200197760142 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.021515906103663 1.0 0.7360795638594819 0.0488236457953868 0.0342361314750581 +Glycoprotein biosynthetic process 26 63 3.5815446585133457 0.0003415687355652 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.0003799055052812 0.603038217660401 0.5483590128255319 0.0172419469934396 0.0001315306974784 +Sphingolipid metabolic process 17 34 3.573444669925028 0.0003523157156908 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 1.904526171336888e-05 0.3654998372428625 0.228437391614845 0.0004398170742491 4.251465468562368e-05 +Cation transport 58 167 3.5312697559273376 0.0004135697397225 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 3.080683539261072e-05 0.2152607060183915 0.0207966076301852 0.0178884431979398 7.663280315615315e-06 +Atp synthesis coupled electron transport 24 47 3.4325905537953365 0.0005978442001763 11.567961165048544 37.61407766990291 0.6403585631460136 0.4181082416574377 5.189865284224125 3.9859091462453993 1.417482213086961 0.3703097362636519 1.7441836762093449e-06 0.006163378346249 7.357527465998784e-07 2.505470472457979e-06 2.3315619029551103e-08 +Organic acid transmembrane transport 26 32 3.41234813065657 0.0006440580338666 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.0279766147689593 1.0 1.0 0.0444212272681039 0.0397101526831211 +Glycoprotein metabolic process 30 72 3.3954552660164143 0.0006851456898522 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 0.0014099499704418 0.6674460421157596 0.6432456701991021 0.0216689429972678 0.0006197995216803 +Golgi organization 22 63 3.387433584022829 0.0007054979620979 16.643203883495147 56.43689320388349 0.631232933893225 0.5683910993217528 6.594450257690171 8.413373430660274 1.0599635722797485 0.3790700076783576 0.00014447324925 1.0 0.7002848572935141 0.0309649911309741 4.706873586716368e-07 +Localization within membrane 71 197 3.3694370981791963 0.0007532188060552 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 4.733959006045194e-07 0.2001597763973769 0.0418069049940507 0.0006349858536602 3.8764330409404496e-08 +Carboxylic acid transport 24 33 3.363846980314855 0.0007686414751115 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.1033078009081187 1.0 1.0 0.0137128382989162 0.1374763991753785 +Organophosphate ester transport 14 31 3.344062521037761 0.0008256112910116 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 1.0479745994488556e-05 1.0 0.5351022899588459 0.002958524345255 2.278200239747344e-05 +Intracellular protein transport 104 354 3.327736865514743 0.0008755452267368 72.23543689320388 320.84466019417476 0.4871189760263694 0.7214714639205947 20.45645165050656 29.914524602040487 1.0524664106682724 0.3751399671828122 1.183029708251762e-09 0.1090024786788255 0.0021921755067098 2.0505376723496027e-05 4.757555205008459e-12 +Aerobic respiration 30 96 3.316825301584548 0.0009104652731437 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 1.0373665376021195e-08 0.0009492885248983 3.26793645008948e-07 8.789602108503377e-09 5.019153050513301e-10 +Membrane fusion 16 49 3.286425501602919 0.0010146760970819 11.592233009708735 41.140776699029125 0.24764888033976 0.6429045305046197 5.404397514006145 5.499742922380336 0.8586283816511532 0.3399356769366213 0.004691090431438 0.4187146588043743 0.0929934383816013 0.0545097952893404 2.6035913525787616e-05 +Carbohydrate derivative transport 13 20 3.265057092223198 0.0010944201488636 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 7.992822042043104e-09 1.0 0.3593428278464597 1.2512495443795471e-06 1.9245529128315722e-08 +Organelle membrane fusion 15 37 3.252588492172929 0.0011435898072118 9.026699029126211 29.49271844660194 0.2503440438263548 0.5991935201964022 4.297974887399588 5.110663265938685 0.9179616425810708 0.3357137012753883 0.0015085004362212 0.3371313972628795 0.1967082241040804 0.0551022953292233 2.631621948630412e-06 +Cellular respiration 41 112 3.2209752010767168 0.0012775520215464 27.975728155339805 102.1019417475728 0.3887198796668061 0.4496840882999475 12.70690482749566 7.191843824002275 1.6294784865611704 0.3894421445164553 2.6262100574218672e-08 0.002043613805171 2.346178910411689e-07 2.881935755789096e-08 1.9269067564399606e-09 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 12 29 3.1479359448284185 0.0016442772048961 7.771844660194175 26.825242718446603 1.1714448828781496 0.3436005361805324 3.811248488859092 3.450558374586287 1.1733172803389544 0.345676809182098 0.000217969027331 1.0 0.0748026769138462 0.0001236545565102 1.1206321672316697e-05 +Cytochrome complex assembly 13 15 3.118504010489492 0.0018177166815984 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 1.43453594891796e-08 0.151306852499084 0.0041517217414646 0.000144725329193 3.095893887128017e-08 +Organelle disassembly 18 49 3.114799380465836 0.00184070056868 11.983009708737864 49.20388349514563 0.433561938027762 0.6160490735942882 4.954374615918461 6.142102393453674 0.8047024382669711 0.3415228222424311 5.752262813940439e-05 0.3926779415133941 0.2605001929873321 0.0124287342519901 8.347378531813546e-06 +Sphingolipid biosynthetic process 11 19 3.092119023947194 0.0019873314772416 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 0.0002816684085482 0.2480154974279715 0.4353012614103685 0.0138556470380734 0.0004875982127202 +Intracellular protein transmembrane transport 10 22 3.090942625515213 0.0019952218280356 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 2.5262095056170573e-05 0.0012844156650938 0.0091243340822671 0.0007016746800212 7.133480197010416e-06 +Cellular macromolecule localization 143 578 3.0779273286402797 0.0020844574047045 116.74029126213593 544.3228155339806 0.3819130491508938 0.7577794226812853 28.882302639166586 53.383983306101904 0.8794377571334007 0.3523979567946485 8.541943680590481e-07 0.2935365391989054 0.0237493043593717 0.0002005367111567 1.1574901213422856e-08 +Protein localization to endoplasmic reticulum 20 35 3.025279262230222 0.0024840365207428 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 7.1435749731432284e-06 1.0 0.1039407380726692 0.0120464435451714 3.768973044350322e-07 +Autophagy of mitochondrion 14 33 3.013608307811817 0.0025816087420345 8.643203883495145 32.55582524271845 0.5912176019297528 0.507260115546458 3.9310041488944902 4.499114265424183 1.01585008111736 0.3556742421157408 0.0005837201318629 0.3075216202298709 0.1656331484196294 0.0101205340460747 6.539147531349342e-05 +Vacuole organization 26 59 3.0075596894065426 0.0026335440099523 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.0488881805059069 1.0 0.7787545592403144 0.5203291084292261 0.0082876681361594 +Establishment of protein localization to mitochondrial membrane 12 19 3.003047749771189 0.0026729048986697 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 1.393997777641473e-07 1.0 0.0021303683071518 3.671693537728937e-05 2.6557460223247744e-07 +Endoplasmic reticulum membrane organization 6 9 3.001158012821461 0.0026895495995944 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 5.074023283755038e-07 1.0 0.0066572828402184 2.831336309208378e-07 8.104989222609044e-07 +Atp metabolic process 42 122 2.98656092297786 0.0028213461632198 25.97087378640777 107.69417475728156 0.2650120939459569 0.5409439866831242 10.270805368899644 8.059768543771504 1.2580915670575048 0.3757529915372982 9.669145568837974e-07 0.0032938072453758 7.679648797665399e-07 8.209377547165479e-07 1.0186449134216356e-07 +Process utilizing autophagic mechanism 54 167 2.9653117476767545 0.0030237634355576 37.22330097087379 158.8252427184466 0.4533218180510577 0.6759877406594806 11.85403297791327 20.589929287102564 0.8897283418769861 0.36588075882003 0.0015926852750744 0.6310562795845085 0.2481142865295273 0.0105392123187233 0.0001881094648544 +Macroautophagy 42 107 2.963192223296382 0.0030446637077363 25.570388349514563 102.68203883495146 0.4734815024857951 0.6429834425349866 8.949285204664525 14.162660044372751 0.8554944786686205 0.3590213706304501 0.0564062488419641 0.3652641381602879 0.7277592499916454 0.1942051991580476 0.0049575631200173 +Glycolipid transport 3 5 2.9550475834954626 0.0031262083053824 1.4368932038834952 3.2184466019417477 0.6463265816527453 0.2804806185071016 0.8495561709644135 0.7701024484633391 1.4290734526194493 0.2737963170174182 0.0002518200710585 1.0 0.0743799864466655 2.1797401302891516e-05 0.0003286021100258 +Establishment of protein localization to organelle 57 188 2.944821658189967 0.0032314086465325 40.4247572815534 180.123786407767 0.6176411706537287 0.628535284461401 14.116769229706104 14.40373863390995 1.0281809729691214 0.3983757503188239 1.080385783948042e-08 0.2453264270323385 0.0558831019376008 0.0026387731666248 9.799863298484432e-10 +Tetrapyrrole metabolic process 8 22 2.90709061619284 0.0036480750295038 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0001279607187288 0.0188245552589776 0.0085749794431607 8.01491828486157e-05 0.0002155385692345 +Hormone metabolic process 15 30 2.90640581716034 0.0036560694319882 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0001116227277025 1.0 0.6098780660493645 0.4186732079295251 6.189616675557875e-05 +Protein exit from endoplasmic reticulum 14 23 2.9006050546292106 0.0037244297025107 7.002427184466019 21.233009708737864 0.6943602976218084 0.4745028866201709 3.210645812910548 2.182026685495945 1.0430444956616387 0.3507892727806736 0.0001059730540048 1.0 1.0 0.0198035379531722 2.990302515741305e-05 +Vesicle mediated transport 100 389 2.8854610310432127 0.0039084084458977 80.64805825242719 354.7718446601942 0.3002670711784583 0.7468304035232791 23.646053491950397 43.46537941024834 1.061791523718338 0.3560152131667141 0.0115221174137831 0.7288535919841466 0.5101560106344956 0.1396675160592459 0.0020140215086994 +Selective autophagy 10 26 2.876425935444406 0.0040220657235241 7.861650485436893 28.031553398058257 0.6116968756419903 0.5194450063363468 3.450451665126401 4.3159755745103565 0.9002253779314615 0.3454803983634653 0.0030707112115906 0.2766173679843171 0.4775398588675821 0.02289977346361 0.001360170383234 +Regulation of mitochondrion organization 15 47 2.864074152646782 0.0041823009162207 12.08980582524272 45.08252427184466 0.8217268052205459 0.4563186211764868 4.409741308614158 5.146210353910189 1.120993905462196 0.3778427085178187 0.0001373632922097 0.0993430224952972 0.2890592178487741 0.0014642245811675 8.491645604992822e-05 +Steroid biosynthetic process 22 50 2.8586572958229546 0.0042543812709876 11.728155339805824 44.80825242718446 0.9874364787035632 0.3935759881445143 5.016369659264937 4.35272817633461 1.2862817592315925 0.3680333006848349 0.0001116227277025 1.0 0.6098780660493645 0.4186732079295251 1.54687245168943e-05 +Mitochondrial electron transport cytochrome c to oxygen 4 7 2.815069683211287 0.0048766658365402 2.6189320388349513 6.021844660194175 0.7576771538928655 0.3133819177040797 1.4641113893518565 0.9306060741204804 1.2097595052740109 0.2966582872605096 0.0001135969051053 0.0561990347849709 0.0001778916397324 0.00262770885776 0.0001575214550341 +Amino acid transport 16 19 2.7980211155974315 0.005141675119177 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.2022607676908506 1.0 0.4876012483283494 0.2338841850044661 0.2430359635228135 +Glycosylation 19 52 2.785775113557013 0.0053399904534179 13.33495145631068 45.42718446601942 0.831363055351092 0.4028474919440285 5.5712021107485015 7.578523489860055 1.3433056638769032 0.3649215649501745 0.0324278763270866 0.5446368300228982 0.7934388322888715 0.0987202887748049 0.0053668451056778 +Endoplasmic reticulum tubular network organization 7 11 2.7713489633341184 0.0055824563934478 4.150485436893204 10.555825242718448 0.8961707031484618 0.3171343629503343 2.1669796342432037 1.8339543060404635 1.2935176897309475 0.3199619326088047 2.834764473614579e-07 0.0786913117950012 0.0005309775927247 1.8818469985730976e-06 4.811826196161669e-07 +Respiratory chain complex iv assembly 7 9 2.769136400719083 0.0056205099453086 2.7475728155339807 6.451456310679611 1.036831430168084 0.2562354664331627 1.605321530277248 1.669274831081891 1.262804896468415 0.2848709091577191 9.144754634640456e-06 1.0 0.0237627189197599 0.0028478177309091 1.515921045849114e-05 +Nucleotide transport 10 15 2.76239144755952 0.0057379638591599 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 6.123688801217483e-09 1.0 1.0 2.914413274201657e-05 1.258895515477494e-08 +Atp transport 5 6 2.7483608554632912 0.0059894050738467 3.4805825242718447 6.233009708737864 0.5838786306840471 0.3211615036091749 1.83337760624298 0.8807971179633459 1.3636108978108328 0.3170401972517012 6.26779859131247e-07 1.0 1.0 0.0010588751859522 9.4206715064497e-07 +Protein import into mitochondrial matrix 7 10 2.7445076007561444 0.0060601751076028 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 1.757498356704878e-06 0.0022827689145391 0.0088504827764808 1.972516813028553e-05 1.3888266358141086e-07 +Electron transport chain 25 78 2.716350920774818 0.0066005914235165 19.550970873786408 67.77184466019418 0.3712062453977176 0.4872800905659868 8.486701420407794 5.37626783377928 1.3790913022045077 0.3735693075609537 7.223568567803847e-06 0.0253511637379553 3.777954081035598e-05 0.000353075219544 3.348269330134652e-07 +Protein localization to organelle 80 341 2.71404465741215 0.0066467205446072 67.3495145631068 323.95873786407765 0.2673038377247629 0.817015428896562 19.766210620364816 30.728939371736654 0.7017218037327799 0.31039729979455 1.0199808417076965e-06 0.2750456780317809 0.0927377237052993 0.000387375669817 2.3947317099510077e-08 +Cellular ion homeostasis 33 96 2.713793856370418 0.0066517544180704 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0002715754899649 0.379151373575087 0.4904150555504759 0.4936991435431352 5.85866351918042e-05 +Ion homeostasis 37 115 2.706050314568434 0.0068088728871524 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 0.0005264621691381 0.2134389652995229 0.3963517524522892 0.4135195867456973 6.938134997781419e-05 +Mitochondrial cytochrome c oxidase assembly 7 8 2.704103658110947 0.0068488920110192 2.344660194174758 5.764563106796117 0.9954600272926416 0.2681565835601643 1.449018962088891 1.4364892997002987 1.2150903662861117 0.2820677765861404 3.5302578715998566e-05 1.0 0.018640880521655 0.0017432511761074 5.493155547881244e-05 +Protein transmembrane import into intracellular organelle 8 14 2.701008910024413 0.0069129486526091 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 4.050513665119486e-05 0.0090330503435184 0.0334071197556988 0.0006954184772239 7.984082923112889e-06 +Energy derivation by oxidation of organic compounds 33 135 2.658131716255725 0.0078575176943955 30.652912621359224 122.18932038834951 0.2541815110246533 0.5071130371174295 12.61138398748304 8.311769788309597 1.4201467433346076 0.3884313364311733 4.956875157385222e-06 0.0059885984942463 3.3892578141621784e-06 1.7343451533848272e-06 7.307591533415258e-07 +Metal ion homeostasis 27 85 2.6525700804693764 0.0079881543436057 22.37864077669903 79.5 0.7762327689006491 0.4501210966631583 8.485414676383348 8.298876985671072 1.3957415688189287 0.3857448193070677 0.0083484593484473 0.1320457949075564 0.2465206288516762 0.6171515226191903 0.0021704814349809 +Divalent inorganic cation homeostasis 20 60 2.646621908317468 0.0081300195428672 15.361650485436892 54.019417475728154 0.5485088157809707 0.5170537035394376 6.04857242197355 6.215359275440269 1.1779017300469032 0.3778837346959196 0.0384264094055614 0.5891657340012217 0.8319470589363818 0.9392564173754272 0.0076758096099639 +Liposaccharide metabolic process 12 20 2.644269383583439 0.0081867472687056 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 0.0152869165296921 1.0 0.4297892617739207 0.1655021226103433 0.0215069931551279 +Ceramide metabolic process 10 22 2.641208504492848 0.0082610861308318 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 0.0039152673933363 0.2406936845278361 0.4242240140575919 0.1596086760652474 0.005918859062877 +Regulation of hormone levels 22 65 2.640596322853207 0.0082760263223182 15.682038834951456 62.25485436893204 0.7754141622249116 0.4638741971732045 6.630568201753413 6.49574922456989 1.111399769110166 0.3798141702267368 0.0196870660037008 1.0 0.8797807104615281 0.608151722626576 0.0185295645038797 +Membrane docking 14 30 2.639800417538925 0.008295486404791 7.973300970873787 28.83252427184466 0.3013065671948621 0.638505559524285 3.967313754164099 3.197937811998676 0.8147042438070861 0.3288047187933706 0.0034009640443514 1.0 0.4825947600252522 0.4934040207883591 0.0003919277181498 +Positive regulation of antigen receptor mediated signaling pathway 1 5 2.637958638807956 0.0083406754183037 0.924757281553398 3.0194174757281553 0.4084127789513044 0.4960633180960504 0.94338200177973 1.0859256936465698 1.0749372708606686 0.3246431094939104 0.1149663982153726 0.0607401038440192 0.1180585699575878 0.0382400085743442 0.1289341732663725 +Positive regulation of t cell receptor signaling pathway 1 5 2.637958638807956 0.0083406754183037 0.8349514563106796 2.7354368932038833 0.4108640728895311 0.4770828834573499 0.8987271190615724 1.0336130209539225 1.1304428701546418 0.3243109232468945 0.0597114340227566 0.0424464003246627 0.0832836732680532 0.0188064524051028 0.0675218785318175 +Proton transporting two sector atpase complex assembly 3 5 2.635043149147853 0.0084126588039319 1.7432098765432098 4.6839506172839505 1.079697689782964 0.2705190312822739 1.1688274457451555 1.1775111637565157 1.0292886485906785 0.2668917829180481 0.0231652698963574 1.0 0.1265462710440741 0.0439142352380576 0.0277461310389573 +Positive regulation of blood circulation 3 5 2.628749351132259 0.0085699501006559 1.6116504854368932 3.924757281553398 0.6685578971888424 0.3646934888838808 1.007091454748733 1.005648459742718 1.1685725886577618 0.3064822812176077 0.0021455018963906 0.0607401038440192 0.1180585699575878 0.2731207001200411 0.0027630263410089 +Attachment of gpi anchor to protein 3 5 2.625327614759471 0.0086565630507347 1.7281553398058251 4.050970873786408 0.3650490188514708 0.4588417110466823 1.1121061515765476 1.035685612757101 1.021268150080817 0.3062595682607533 0.0016684345466174 1.0 1.0 0.1368589802283267 0.0020376306093415 +Regulation of protein exit from endoplasmic reticulum 5 6 2.6152362723342284 0.0089165750951376 2.487864077669903 6.131067961165049 0.614536574202818 0.458469843561175 1.597129798474628 1.7824129563144424 0.9381550143256092 0.3206976005104832 0.0113062372974908 1.0 1.0 0.0834574734746242 0.00223229240551 +Protein insertion into mitochondrial inner membrane 5 8 2.60856550963766 0.0090922606522096 2.45873786407767 5.665048543689321 0.6692509200083531 0.3406754428009103 1.501050234026552 1.645659707056692 1.2686438529444872 0.3125184360343283 0.0001135969051053 1.0 0.0056684159955205 0.00262770885776 0.0001575214550341 +Cellular copper ion homeostasis 3 5 2.568216261184141 0.0102223360036139 1.633495145631068 4.138349514563107 0.8027486766067657 0.3358654651123308 1.1881879887367894 1.18353805365164 1.0950331419070014 0.2903029711159642 0.0188221125346629 1.0 1.0 1.0 0.0225979674873623 +Sterol biosynthetic process 14 28 2.567155019550963 0.010253676121223 7.281553398058253 24.52912621359223 1.190088798384403 0.3136799329736269 3.292879861326439 2.61838648411319 1.1232845583768152 0.3105481837594456 3.779602700465877e-05 1.0 0.3655284832956332 0.1048323445251165 1.1206321672316697e-05 +Oligosaccharide lipid intermediate biosynthetic process 3 6 2.55250973395697 0.010694992103494 2.2742718446601944 5.390776699029126 0.4920123476052065 0.3335995467983793 1.5024311055989734 1.8021595402153228 1.3008390374829126 0.2934249582958821 0.0076703170263664 0.083126337411673 0.1596960736798767 0.0087554356838108 0.0097510399506001 +Lipid metabolic process 102 300 2.551532653675633 0.0107250273507264 70.49514563106796 273.7014563106796 0.4234492243219149 0.5257500979287635 24.98470358696109 28.74867152381156 1.6795947056521872 0.4126649977131845 5.926369173162197e-10 0.5245203931968996 0.4810678199457338 5.958378005099098e-05 1.7705403596894118e-10 +Lipoprotein localization 2 5 2.549686425560869 0.0107819848234826 1.7451456310679612 4.762135922330097 1.33870340128666 0.2150435313503844 1.1193794779630346 1.3835803073772095 0.999398972942542 0.2555578059866495 0.1001749696470511 1.0 1.0 1.0 0.1125747569923622 +Lipoprotein metabolic process 12 18 2.5429752338332423 0.0109913019409293 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.0900911605120068 1.0 0.1967082241040804 0.0551022953292233 0.1181853417157704 +Mitochondrial electron transport ubiquinol to cytochrome c 3 5 2.5421463999367244 0.0110174015626032 1.5048543689320388 4.206310679611651 0.8658650693935839 0.2665349265497743 0.9514810775456936 0.7935779738409815 1.3072925004771625 0.2886561243868636 0.0597114340227566 0.0424464003246627 0.0031504918831051 0.0188064524051028 0.0005688349419973 +Positive regulation of autophagy 7 29 2.5415556727106283 0.0110360369020034 7.036407766990291 30.483009708737864 0.6693528554580194 0.4628135853102879 3.235293043364778 5.784747493453153 0.9361869896860724 0.333658419297932 0.0673939197710091 0.1008495778431075 0.292624050209727 0.0545097952893404 0.0939632758155837 +Sphingosine biosynthetic process 3 5 2.5370716897764134 0.0111784060337316 1.91747572815534 4.20873786407767 0.5236437336099039 0.253544361366954 0.9618880285708752 0.5531212048069467 1.4879043514061585 0.274550754534842 0.0272184914162367 1.0 1.0 1.0 0.0309764532364539 +Lipid biosynthetic process 64 158 2.512627012497469 0.0119835959018483 38.012135922330096 141.7257281553398 0.5620793375816577 0.4367444072022249 15.729119254593195 17.314902336322657 1.553306672697969 0.3832082090559359 8.398800197234923e-06 0.611897199111217 0.7816800065592221 0.0925440753565729 3.469158776366535e-06 +Porphyrin containing compound metabolic process 7 19 2.5100155282032626 0.0120725852721361 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.0001333878226951 0.0121686135974036 0.0045096021611559 0.0001711644149485 0.0002147363626889 +Cellular response to lipoprotein particle stimulus 3 5 2.509770934928071 0.0120809499964218 1.25 3.8470873786407767 0.4175347012534766 0.3798602361667617 1.1183053232979376 0.9442808236527792 1.193491171404314 0.2885743012451784 0.5240718508484606 1.0 1.0 0.3247468214281712 0.1807018090276839 +Lipid localization 34 80 2.495176039113647 0.0125894655084803 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 0.0434150816790785 1.0 0.3573820216030455 0.0887792265974184 0.0406614656106359 +Er nucleus signaling pathway 9 14 2.487031416080617 0.0128814023207233 4.563106796116505 13.361650485436892 0.3617919622488442 0.4304556920046536 2.3428051517114805 1.3174649068389608 1.1974910326877934 0.3346175168774911 0.000996431873224 0.1594721229818057 0.2941077913158182 0.5870305126491255 0.0014896299843671 +Regulation of er to golgi vesicle mediated transport 1 5 2.4799003824166346 0.0131419092959035 2.1966019417475726 5.915048543689321 0.8267152021532312 0.3699978591289015 1.4151359695885812 0.8244249231762646 0.9890575089615372 0.3183740962504898 0.1149663982153726 1.0 0.1180585699575878 0.0382400085743442 0.1289341732663725 +Secretion 47 156 2.4705224929495224 0.0134915834091617 33.99271844660194 147.42233009708738 0.4048828366720226 0.7039215372882776 10.476160889322964 16.385711464618055 0.7463810424968602 0.3447407367793494 0.0260618178012178 0.3775589691339882 0.2758742877890929 0.2188063814371864 0.0367789547340115 +Cellular hormone metabolic process 10 19 2.4671256806181754 0.0136202542641994 5.441747572815534 17.32766990291262 0.9908884218524354 0.2940959275691314 2.8170777488519256 1.7185203072340225 1.2515909253444888 0.3031653223897966 0.0004143613245335 1.0 1.0 0.3513790442708272 0.0001404947310284 +Protein insertion into er membrane 9 15 2.46298536366249 0.0137785540371997 4.451456310679611 12.691747572815531 0.9645901040516046 0.3077872373135509 2.16101217194965 1.431147904526304 1.1733171268605926 0.305304417896891 3.0496197341168823e-06 0.0049155620827658 0.018640880521655 0.0017432511761074 5.100313122590283e-06 +Lipoprotein catabolic process 1 5 2.4615946366277166 0.0138320900716841 1.529126213592233 5.211165048543689 0.7074087979902727 0.279320898549559 1.1111204061152251 0.9407555329409328 1.2623530327786678 0.2599848817817885 0.1459993121590467 1.0 0.1349531130589082 0.0498779046475234 0.1630814235328921 +Protein depalmitoylation 1 5 2.4615946366277166 0.0138320900716841 1.3203883495145632 4.468446601941747 0.9114659728007516 0.274733419943775 1.0188856680336909 0.6320520706114182 1.1467191069327447 0.2583665413440971 0.0724548439670735 1.0 0.0921025797166938 0.0231366382468947 0.0817606313480972 +Vesicle fusion with golgi apparatus 4 6 2.441470405514192 0.0146275871936483 1.5364077669902914 3.966019417475728 0.1702699360909109 0.5796956959617573 1.095504808379403 1.183958589381628 0.8777851290846 0.309082893164015 0.0043638244151776 1.0 1.0 0.1781979724676324 1.3106068439724131e-05 +Ceramide biosynthetic process 6 11 2.437697441565583 0.0147811397490853 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 0.0197422588784401 0.1553991536419083 0.2872333566147377 0.2076979954646016 0.0257423149537502 +Vesicle docking 9 17 2.4360473313794007 0.0148487414428089 5.046116504854369 16.300970873786408 0.2955335573812314 0.5566344803804099 2.726231700974349 2.3037957343391864 0.8857805503827542 0.3078464388536641 0.0152352559216179 1.0 0.3530974878629287 0.2978006616879862 0.0012835617051806 +Steroid metabolic process 29 73 2.432970431101761 0.0149755237894539 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 0.0006906357495602 1.0 0.4440550029604954 0.3271865843905714 6.41910658057664e-05 +Inorganic anion transport 12 27 2.431666550266287 0.0150295366798987 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.0010173263987006 0.0432831882721129 0.0285769937968429 0.0013505003452077 0.0017102987040416 +Glycolipid biosynthetic process 7 10 2.428464008482555 0.0151629300180675 3.3009708737864076 8.701456310679612 0.8778541677747596 0.2891249509557468 2.0940737065519093 2.1465026455410077 1.206628042966233 0.2848826766737565 0.0220996622834804 1.0 1.0 0.2166326226637888 0.0287420990175065 +Amino acid transmembrane transport 13 15 2.427778364675999 0.0151916238089944 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.3591985765393236 1.0 1.0 0.3157753203157507 0.4011073361813396 +Cristae formation 7 9 2.427334839767608 0.015210210524815 4.740291262135922 8.861650485436893 0.8982766043222677 0.3392698633906088 2.216011442046921 0.6593503673812457 1.2485531022675598 0.3418736408093433 0.0002662511149375 0.0652597674910206 0.0077184558590264 0.0041946485896371 2.7323384312904545e-05 +Gland development 14 72 2.425857701838557 0.0152722571439365 13.315533980582524 70.03155339805825 0.3377251159437185 0.619362793080585 5.179070225840264 7.6825027851127485 0.7642435987942063 0.3217888637120522 0.2610192475554533 0.1441765718609627 0.0482558207910852 0.220630820050339 0.3531013516204405 +L amino acid transport 12 13 2.4185236655072546 0.0155836318418753 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 0.1983969858228972 1.0 1.0 0.1988041978590851 0.227264848110046 +Response to muscle activity 1 5 2.417371426000775 0.0156330558585238 1.1820388349514563 4.364077669902913 0.5239254658848286 0.45987221631934 0.9696199427834098 0.759068715173887 0.9441019188718152 0.3060195977413827 0.0369771588694818 1.0 0.0653907127050202 0.0113265963942617 0.0419919493306108 +Sphingoid metabolic process 3 6 2.4089850787823357 0.0159969519902751 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0724548439670735 1.0 1.0 1.0 0.0817606313480972 +Positive regulation of phosphatidylinositol 3 kinase signaling 1 5 2.402825412788661 0.01626895252295 1.3616504854368932 4.405339805825243 0.1060046460851379 0.5092928061849754 1.0851089132284029 1.598928837760243 1.0900635375420673 0.3161280547591697 0.4600843832656368 1.0 1.0 0.5661975770404395 0.4967295098899271 +Regulation of mitophagy 3 6 2.399803287916808 0.0164038844786453 2.033980582524272 6.730582524271845 0.7938894190377023 0.2859156513857533 1.5052692819802862 1.0417203147023346 1.2011910390869405 0.2760404746280959 0.0015400390303818 0.0561990347849709 0.1094892401774078 0.00262770885776 0.0019884945269669 +Nuclear envelope organization 13 33 2.395937527134132 0.0165779155997067 8.555825242718447 29.70873786407767 0.3742592988081523 0.5658154731413123 3.620906131367995 3.382223856109787 0.8839532199066901 0.3277754788938732 0.0019116532704317 1.0 0.0128487417044244 0.001374788533299 0.0029392451780606 +Mitochondrial atp synthesis coupled proton transport 4 11 2.385341933679426 0.0170632533423282 3.9927184466019416 10.769417475728156 0.5022502301293951 0.29867761594221 2.4440229028906213 0.8937412640542226 1.3849431163992842 0.2834040324316194 0.0009801725371322 0.083126337411673 0.0126574737404708 0.0007869115437374 0.0013369974246366 +Export from cell 55 143 2.37594534317896 0.0175040554070871 32.60436893203884 135.66747572815535 0.3992493838217476 0.6865741169713714 10.348597782214936 15.653208065897076 0.76303420232271 0.3488015490888403 0.1128300188188689 0.8777082207522594 0.7843887374012481 0.5897566126525674 0.1372177704765961 +Lytic vacuole organization 15 29 2.374332761294478 0.01758069840272 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 0.005387745895304 1.0 0.4407605172427877 0.1774767594454888 0.0080767934135705 +Respiratory chain complex iii assembly 4 6 2.3724045621847423 0.0176727281353239 1.8470873786407769 5.160194174757281 1.360931378136811 0.1995688008303064 1.0650749835200868 1.2360161344522411 1.0120439004969468 0.2366879233397748 0.0043638244151776 0.0378187125466048 0.0743799864466655 0.0148625463558957 0.0053031795330487 +Cellular homeostasis 43 158 2.3686323326998826 0.0178539920410976 35.03155339805825 140.69660194174756 0.4666088113804902 0.5685618966047314 11.62423291193178 14.777892439656425 1.1736922314243927 0.3887657095146841 0.001589854509014 0.6092881231437158 0.3842667100367766 0.2264843045833507 0.0007103408452323 +Copper ion homeostasis 3 6 2.366700621520698 0.0179474441032416 1.6771844660194175 4.669902912621359 0.4484316971142749 0.3058603694529516 1.2128614304476144 1.4202990900289796 1.3716690980071935 0.284002300922153 0.033335161975655 1.0 1.0 1.0 0.0397387250697101 +Protein insertion into er membrane by stop transfer membrane anchor sequence 4 7 2.361980230671638 0.0181776115252318 1.9635922330097089 5.686893203883495 0.4346685280287892 0.4212908647152366 1.4128861560779629 1.136987613501037 1.0888942312003185 0.31377177158709 0.0007024718324135 0.0470522829573702 0.0921025797166938 0.0231366382468947 0.0009118158302113 +Protein localization to vacuole 8 23 2.3467824485228803 0.0189363077052833 5.20873786407767 20.24757281553398 0.5437651170857908 0.3970016112497027 2.9079938968471533 3.678442701839641 1.178287503307516 0.309681546976434 0.0139689277020097 1.0 0.4242240140575919 0.048897845662748 0.005918859062877 +Zinc ion transport 4 5 2.3453002385096293 0.0190117632425239 0.6973293768545994 1.9525222551928785 1.2400878900463903 0.2228715481064509 0.810040106782955 1.041056807388981 1.502966485729551 0.2675839368124507 0.2119278063992609 1.0 1.0 1.0 0.2348875720984273 +Ceramide transport 2 7 2.339492554306602 0.0193099564716787 1.779126213592233 5.310679611650485 0.994079753441996 0.2057455404068654 1.027416031856974 0.785538294365343 1.3065287972688011 0.2361222749942 0.0188221125346629 1.0 0.1180585699575878 0.003355333516566 0.0225979674873623 +L alpha amino acid transmembrane transport 10 11 2.335468753521645 0.0195189463786655 4.480582524271845 10.533980582524272 0.7590361902351016 0.3223730555033793 2.606398335255894 1.1951807271273862 1.273814103695318 0.3116596719827348 0.1867206744020754 1.0 1.0 0.1899587232036964 0.2143350029099695 +Calcium ion import 7 14 2.331722608745909 0.0197152886415874 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.0246324497731783 0.1635258499471353 0.048990890514732 0.0596874537258691 0.0081853110588452 +Regulation of steroid biosynthetic process 5 10 2.33157499418907 0.0197230605839509 3.186893203883495 10.259708737864075 0.6168896095149775 0.3174156062343823 1.783561142158544 1.373475469974866 1.265753415239616 0.2847701277650337 0.0273444944939211 1.0 1.0 1.0 0.0353817250131281 +Dicarboxylic acid transport 12 15 2.327161661795225 0.0199566626659335 5.718446601941747 16.097087378640776 1.1205667041867788 0.2998586575349944 3.584398436287638 2.226340822602054 1.0973546365412417 0.2986830136605488 0.0400474364873682 1.0 1.0 0.0032788281256578 0.051296284939533 +Positive regulation of macroautophagy 6 18 2.3251754489307435 0.0200625805716661 5.058252427184466 20.34223300970874 0.7197293510270528 0.4154159089925248 2.5734840677494253 3.836065802213299 1.0387053871978371 0.3265560923975395 0.0181838866334971 0.0335548880884004 0.1132051672598368 0.0571243888921134 0.0254457366029634 +Transition metal ion transport 10 20 2.313319927634688 0.0207050558521255 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 0.0048565558279735 0.2480154974279715 0.1100932826860655 0.0543044475705096 0.0073008402117251 +Amyloid precursor protein metabolic process 6 20 2.313138569883224 0.0207150217144236 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.0115801031988502 0.0285808600856777 0.0157478410048603 0.0438041643494559 0.0164244734054917 +Prostate gland development 2 6 2.312291423682003 0.0207616289938419 1.6092233009708738 5.975728155339806 0.8122203292357496 0.3302673624761357 1.2128808594676108 0.7270055647304389 1.0647320376486975 0.2858771068016162 0.1639543464099131 1.0 1.0 0.1724444479617574 0.1889957663081205 +Gpi anchor metabolic process 5 7 2.310791802401146 0.020844357531395 2.400485436893204 5.657766990291262 0.3080589762515228 0.4676033624934861 1.4738167072879584 1.5318187882629617 1.0335174561584772 0.3098879122060578 0.0134770599498747 1.0 1.0 0.090818300458346 0.017002584405276 +Proteoglycan metabolic process 7 11 2.308379389218436 0.0209780443289282 3.0558252427184467 7.347087378640777 0.90943742591388 0.2775323863615319 1.813993622553226 2.3052106999156825 1.19959130355936 0.2714444012698452 0.0122990118624179 1.0 0.3404254693467198 0.0854582473740603 0.0168189007239576 +Positive regulation of peptidase activity 13 44 2.3057825742553537 0.0211227843959711 10.402912621359222 41.05582524271845 0.5528457293594794 0.5353148532065843 3.6877903061155113 4.060739093918417 0.9383664509883394 0.3555881721715914 0.0032364021229407 0.114689393659792 0.324578641637734 0.3370386727072499 0.00577480294094 +Regulation of alcohol biosynthetic process 2 5 2.305064049578235 0.0211629865455726 1.6771844660194175 4.694174757281553 0.6441414994535534 0.3918503348179894 1.2287667805258018 0.964750105248192 1.022157937878104 0.3006721743490211 0.3477396452921003 1.0 1.0 1.0 0.3798345415961738 +Regulation of cholesterol biosynthetic process 2 5 2.305064049578235 0.0211629865455726 1.6650485436893203 4.609223300970874 0.6675921621720221 0.3903379911361398 1.2205528540330282 0.9058667354361158 1.013338356321453 0.3026321490998659 0.1620941907570236 1.0 1.0 1.0 0.1807018090276839 +Amino acid import across plasma membrane 5 6 2.303879418059379 0.0212294133704544 2.400485436893204 5.689320388349515 0.4658843139000829 0.3469166214138216 1.544580175870074 0.965714446664715 1.2016267132750456 0.2871391427948346 0.2629734920461806 1.0 1.0 0.4172977923286156 0.2898287915273368 +Transition metal ion homeostasis 11 27 2.3006273605136207 0.0214127031461344 6.640776699029126 24.57281553398058 0.9239194315613378 0.3015424973151205 2.934079531592402 2.8081087224394015 1.2471169312381896 0.2974369333820005 0.0279766147689593 0.0564048148733258 0.0415809882988902 0.1288237731053 0.0151062022161933 +Positive regulation of autophagy of mitochondrion 3 5 2.290129845639025 0.0220137907042468 1.854368932038835 6.12621359223301 0.5582523218368712 0.3671654381748088 1.4221395544857194 0.967226157532586 1.067351028932407 0.2704601289024815 0.0010645583219727 0.0516364610584135 0.1008375048293403 0.0020064706347618 0.0013781701696679 +Atp biosynthetic process 11 21 2.2847607101310534 0.0223268626336388 6.262135922330097 20.148058252427184 0.2780500302004456 0.4469732075673486 3.3282000880634137 1.2978402958376112 1.0861992627517016 0.3097712264878526 0.0086761605654707 0.1755724648168266 0.0065760397653667 0.0026376358858749 0.0119603409362114 +Antiviral innate immune response 3 5 2.2847382024644936 0.0223281831523145 2.4441747572815533 4.966019417475728 0.1790207298991634 0.4762932720756598 1.3399355326267808 0.1811792000633157 1.0134461763149525 0.3105069800064801 0.0724548439670735 1.0 1.0 0.2175647207167039 0.0105668672564949 +Autophagosome organization 14 28 2.282293639457274 0.0224720098192736 7.182038834951456 26.570388349514563 0.1959965762708488 0.6424664291527115 3.9411160656788633 4.6942845691516135 0.7864117658771023 0.3125757506363847 0.6133951856731434 1.0 1.0 0.898851047947006 0.1651368225347115 +Positive regulation of organic acid transport 4 5 2.280126797415077 0.0226001693146582 1.8567961165048543 5.946601941747573 0.3622827495700632 0.4822345019026507 1.3799456254886664 0.9358362164790908 0.9715216605110036 0.3096986355133196 0.4529312896408254 1.0 1.0 0.2731207001200411 0.4765717690882453 +Endoplasmic reticulum calcium ion homeostasis 6 10 2.2710898187198088 0.0231415412084954 3.412621359223301 8.468446601941748 0.7163576234395546 0.3718536853795897 2.0059706805420334 1.5568434939403433 1.1166052913833018 0.3156746531372333 0.0003360516958199 0.1006582454154426 0.191600110602388 0.4172977923286156 0.0004867641084232 +Purine nucleotide transport 7 12 2.2642254096079943 0.0235602545323128 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 1.3019059260235518e-06 1.0 1.0 0.0011993766429203 2.1902966903943494e-06 +Sensory perception 12 42 2.259971688357254 0.0238230080232666 8.587378640776699 35.48300970873787 0.2801501425459651 0.4439497622713729 3.631661729137722 5.322347342377745 1.1543967333771397 0.3256888258772134 0.0506027563853312 1.0 0.2317711545672773 0.0248455243964004 0.0779968554574975 +Regulation of amyloid fibril formation 2 6 2.259223455751395 0.0238694884851315 2.2888349514563107 5.662621359223301 0.5261836595996398 0.3490055624244857 1.4817896559260575 1.2503440001723864 1.197683561482515 0.297347360341851 1.0 1.0 1.0 1.0 1.0 +Nucleotide transmembrane transport 6 10 2.254956271698236 0.0241360736721703 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 3.002919287037127e-06 1.0 1.0 2.812625820330817e-05 4.754797566677231e-06 +Calcium import into the mitochondrion 6 8 2.242901198535917 0.0249031864659372 2.4563106796116503 6.04126213592233 0.8091317576129835 0.2214807715451704 1.7082137325011066 1.2010296388602073 1.3762222767333927 0.2421218388926935 0.0149736639257102 0.0561990347849709 0.1094892401774078 0.0328731354880699 0.0019884945269669 +Early endosome to golgi transport 6 8 2.2288454175605894 0.0258241918570094 2.320388349514563 6.650485436893204 1.001706299736163 0.3202433583076141 1.526233973035193 1.1381191933763375 0.8656979853859356 0.2689019049302471 0.0015400390303818 1.0 0.1094892401774078 0.2550529546148332 0.0019884945269669 +Sensory perception of light stimulus 7 20 2.2160388755934624 0.0266888398066773 5.009708737864078 15.96359223300971 0.918103407248628 0.3572194322029593 2.4583724414330383 3.147064390877318 0.9947617981182544 0.3055434177582076 0.0095590643458722 1.0 0.4724360815693985 0.0051340314390508 0.0140935967091553 +Glycoside catabolic process 1 5 2.2146379146361745 0.0267849274323614 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 0.3100216140704895 1.0 0.0743799864466655 0.1781979724676324 0.3285208438252537 +Regulation of response to extracellular stimulus 0 5 2.2142096436309364 0.0268143607864883 1.0364077669902914 4.466019417475728 1.2416795343104177 0.2058666180593168 0.8221064046230258 0.7766686887277909 1.0462594039989206 0.2178110962907249 0.3997040719021639 0.0516364610584135 0.1008375048293403 0.2365379696877526 0.4217257773445009 +Er overload response 2 5 2.208900383543898 0.0271815705287072 1.837378640776699 4.473300970873787 0.5113243262281758 0.4611923313960993 1.086215896190079 0.6585994087920162 0.9725988758473914 0.3191192692053483 0.0087377942346259 0.0470522829573702 0.0921025797166938 0.2175647207167039 0.0105668672564949 +Atp synthesis coupled proton transport 4 12 2.205009453021382 0.0274534312008241 4.067961165048544 11.769417475728156 0.4798560195228825 0.3249136059986872 2.5150503707528173 0.8937412640542226 1.340203957668315 0.2941072770431484 0.0016454286882876 0.0919337377678228 0.0155240337321844 0.0011993766429203 0.00223229240551 +Regulation of glial cell proliferation 1 5 2.20044221515266 0.0277755354799444 0.9563106796116504 4.089805825242719 0.9341050469143442 0.3274204875894432 0.8829748814899869 0.9675276073756384 1.0425311720733597 0.2839327622585455 0.1784863028688835 0.0786913117950012 0.1515272625734178 0.3411306657380243 0.1985866733922443 +Negative regulation of amyloid fibril formation 1 5 2.1975922518651982 0.0279781758719959 2.1529126213592233 4.890776699029126 0.3569908231055533 0.4009987139403995 1.2573729209219855 1.077218811389963 1.1293664882470678 0.3015190208545801 1.0 1.0 1.0 1.0 1.0 +Proteoglycan biosynthetic process 6 10 2.191485251014933 0.0284166958996985 2.6432038834951457 6.677184466019417 0.8965384350791714 0.2873226841395866 1.6239641738792057 1.992745053805788 1.1569297556833695 0.2755887487741971 0.0197422588784401 1.0 0.2872333566147377 0.2076979954646016 0.0257423149537502 +Protein n linked glycosylation 7 22 2.186070230064058 0.0288104676031479 6.177184466019417 18.78640776699029 0.2004880128160887 0.4683260162783809 3.1676710128395498 3.0254598797887766 1.208633498192774 0.333447209788965 0.0039152673933363 0.2406936845278361 0.4242240140575919 0.048897845662748 0.005918859062877 +Neutral amino acid transport 4 5 2.18507745548045 0.0288831679331815 2.3228155339805827 4.922330097087379 0.5168518363879385 0.3990476682843565 1.4731130220322628 0.987192944896482 1.0926945809125377 0.308136804548559 1.0 1.0 1.0 1.0 1.0 +Erad pathway 17 42 2.183739994500551 0.028981359122939 9.883495145631068 38.19174757281554 0.3304224870610107 0.6151102195901742 4.326035362628732 4.084618299759124 0.8776780132973124 0.3415212956260079 0.0039949165196695 0.0775893010402436 0.2355439310831054 0.4121736830967311 0.0022768192284096 +Peroxisomal transport 3 5 2.182863796309936 0.0290458418567396 2.4199029126213594 6.206310679611651 0.5152791591885746 0.4397608531291631 1.438341814396029 1.9279897928521967 0.9960993615772044 0.3114134157114668 0.2288716478191821 1.0 1.0 1.0 0.2531867173469597 +Pigment metabolic process 8 29 2.18148271213162 0.0291477317749002 6.730582524271845 27.429611650485437 0.7330558837492486 0.3938325994367372 3.1680652652278396 2.973572406869117 1.1788232115476622 0.3357800616079686 0.0007376030125873 0.0022960708364777 0.0018806372047711 0.000338442961232 0.0012031940780095 +Tetrapyrrole catabolic process 1 5 2.181097001203927 0.0291762426086943 1.2936893203883495 3.888349514563106 1.3644540792548048 0.1853348016647351 0.7198024139502899 0.613093535820443 1.150391861359729 0.234811337893219 0.0187018057934029 0.0002241871259369 0.0008973897437505 0.0055694485300755 0.0213301790272909 +L glutamate transmembrane transport 6 7 2.179511191580481 0.0292937141877138 3.116504854368932 6.616504854368932 0.3175170990129407 0.3936177213286974 1.7421166172873912 0.8323084155048082 1.211420518243718 0.3212678134420738 0.1302665862694917 1.0 1.0 0.0439142352380576 0.1457988469723397 +Exocytosis 29 78 2.1713841795438253 0.0299021437898403 16.961165048543688 72.39563106796116 0.1685031958770574 0.7402195774784479 6.361172161168185 8.909538923258275 0.6212716645622243 0.2932215182854906 0.1012006572032344 0.6437166934391536 0.873701468336294 0.5873882478024665 0.0919506074529148 +Mitochondrial calcium ion homeostasis 7 13 2.1643277625231 0.0304392034916369 4.62621359223301 10.509708737864075 0.2790428491871666 0.3774917598770124 2.1634860921400008 1.7383182679254283 1.294226020505384 0.3175561312397286 0.0002540292093409 1.0 1.0 0.4028006685093745 3.907616018373289e-05 +Negative regulation of leukocyte migration 3 7 2.153326395424232 0.0312930357487559 1.5655339805825244 6.388349514563107 1.0839414642274992 0.2862432737648586 1.19995002173864 1.2770035444730965 0.9459956297737524 0.2624453160295969 0.1620941907570236 0.0026008925831016 0.0100519320580488 0.0561137872346343 0.1807018090276839 +Protein localization to extracellular region 15 61 2.144176933225153 0.0320187125852584 14.08980582524272 60.1626213592233 0.3740636626751541 0.6804633719835338 5.5124918123942495 7.043227203431352 0.6880222056686158 0.320722083725093 0.1382370326314102 1.0 0.536804044935112 0.165527798552531 0.1189350640312587 +Regulated exocytosis 15 37 2.143646282489464 0.0320612393763095 9.385922330097088 34.342233009708735 0.5889869251407832 0.528096964379338 3.868480531815476 4.573760415025692 0.9122431884356956 0.3457208176316948 0.0223845015541583 0.4463627535095094 0.6943670866160305 0.5707162676561247 0.0347006691656239 +Response to progesterone 1 5 2.137556063502988 0.0325527909232694 1.354368932038835 4.567961165048544 0.3842719312454053 0.4842439730306144 1.1723577355080894 1.195762225303476 0.9635234972248428 0.3017168949830429 0.1620941907570236 1.0 1.0 1.0 0.1807018090276839 +Endoplasmic reticulum unfolded protein response 9 23 2.118054135380574 0.0341704832020985 5.922330097087379 20.817961165048544 0.3028076268112233 0.5117002472852509 2.747246884507101 1.9665572199818449 1.041467084382159 0.3322997623752832 0.0027746946815416 1.0 1.0 1.0 0.0042301612836837 +Phosphatidylglycerol metabolic process 8 14 2.1165416116447924 0.0342987700453523 3.7572815533980584 10.78640776699029 0.7074456860764219 0.3298030384317407 2.521619218643941 1.658461595229837 1.2128783939533223 0.2875854965146425 0.0247128756640835 1.0 1.0 0.1219531221716571 0.0308662830144804 +Negative regulation of amyloid precursor protein catabolic process 3 9 2.113394692353335 0.0345669998757245 2.645631067961165 8.78883495145631 0.7296788020743029 0.3749260712143212 1.4314957008524525 1.1001198531094605 1.057374600950545 0.3066940057573566 0.0061836182508931 0.0029386578360865 0.0005309775927247 0.00062382482254 0.0078812527225172 +Positive regulation of response to endoplasmic reticulum stress 4 7 2.104503874674855 0.0353345169792536 2.599514563106796 7.531553398058253 0.8024117711160038 0.3682526496548435 1.5726113825314656 1.2719812977815077 1.0103793589126204 0.3058642465956152 0.1315713232730282 0.1263420182810564 0.2372212797486779 0.4972078859355511 0.1526461610854137 +Positive regulation of cysteine type endopeptidase activity 8 31 2.101060026732823 0.0356356972781763 7.196601941747573 28.478155339805824 0.6118231968344265 0.4994143481361404 2.711480107898675 3.3256882629722657 0.9483693928307184 0.340405399390541 0.019112066109829 0.0680396063598938 0.2107495506364678 0.1693080490378837 0.0283278119546019 +Tail anchored membrane protein insertion into er membrane 7 12 2.092577881109788 0.0363868527764696 3.237864077669903 9.78883495145631 0.7455035093084798 0.3610190702677224 1.8292985819470449 1.3170176672565082 1.0475888307659635 0.3008611564480194 4.550017734709981e-05 0.0742352733278267 0.1432798584585485 0.0062267265321947 6.703246650942136e-05 +Phosphatidic acid metabolic process 5 9 2.089705424947194 0.0366442693931505 2.2233009708737863 6.235436893203883 0.8816881639607732 0.2856229767394486 1.614148841412113 1.5439850574626743 1.1927985254107716 0.2824496640110863 0.111398140820949 1.0 1.0 0.4718643991127431 0.1298078118605267 +Regulation of autophagy of mitochondrion 7 16 2.086860184568825 0.0369007748860532 3.83495145631068 15.269417475728156 0.5599037905354275 0.4319133125136808 2.249474965186929 2.2839109385500524 1.0076019915675485 0.3108342800197468 0.0004699492327699 0.1430638950507344 0.266209970857853 0.0070923684446229 0.000109129133689 +Macromolecule depalmitoylation 2 7 2.0848016024906637 0.0370873132073339 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0149736639257102 1.0 0.1094892401774078 0.0328731354880699 0.018020673376298 +Mitochondrial electron transport nadh to ubiquinone 13 30 2.083700372623126 0.0371874303194963 6.978155339805825 23.191747572815533 0.1359521499798502 0.4918917616449922 3.7503408900263353 2.804232213140088 1.0785274658822177 0.3109762308168006 0.0038134353043835 0.1952735388158895 0.0091243340822671 0.0044406378118471 0.0012835617051806 +Protein localization to lysosome 5 17 2.07942798967206 0.0375780301094974 3.5364077669902914 14.37621359223301 0.6191344010889903 0.3619681772746835 2.0811532251007954 2.18038858944462 1.1869570048706093 0.3022181269423334 0.0246324497731783 1.0 0.3009165941166509 0.0118572988629309 0.0081853110588452 +Potassium ion homeostasis 4 5 2.0785313836101307 0.0376604434301799 2.1019417475728157 4.400485436893204 0.1622475354349707 0.492855050439112 1.2768651374091653 0.828672911031389 0.9823655527272424 0.3091792082522349 0.4529312896408254 1.0 1.0 1.0 0.4765717690882453 +Signal peptide processing 3 6 2.0761005120386264 0.0378846558339085 2.0898058252427183 5.155339805825243 0.788498872885968 0.2357910477072221 1.2938213743418876 0.7208043181852656 1.3841109341751536 0.2490116896927748 0.0116152577017657 0.0516364610584135 0.1008375048293403 0.027832231049335 0.0140126286640228 +Long chain fatty acyl coa biosynthetic process 2 8 2.070154014716008 0.038437924004159 2.6067961165048543 6.645631067961165 0.2459085958317533 0.3937710552533847 1.6983008147735923 0.8926100812185768 1.1931980478816402 0.3084504867564762 0.0280038679646325 1.0 1.0 0.0498779046475234 0.0334620993119388 +Mammary gland epithelium development 1 7 2.068550773245733 0.03858826140565 2.0533980582524274 7.504854368932039 0.4210175862420911 0.5353031153867802 1.3481605975882227 1.6670640805603438 0.7742467778819695 0.2853093207482 0.599118303165053 1.0 0.3467918934582977 0.2887846572413305 0.637323462105345 +Mitochondrial calcium ion transmembrane transport 8 11 2.066903607538884 0.0387432377498395 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.0049015939150874 0.0742352733278267 0.1432798584585485 0.0561137872346343 0.0007388687073799 +Estrogen metabolic process 2 6 2.062686522601908 0.0391424212176292 1.9733009708737863 5.415048543689321 0.3185210331539875 0.4818950250802296 1.3480535326507852 0.7002542863879344 0.9574993140274748 0.3002738809280755 0.1001749696470511 1.0 1.0 0.2550529546148332 0.018020673376298 +Amyloid precursor protein catabolic process 5 16 2.062356597186384 0.0391737982974684 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.0137123465060884 0.0188245552589776 0.0085749794431607 0.0213813720021448 0.0187017730028202 +Neuron recognition 3 8 2.0483610153944003 0.0405246384660076 1.9368932038834952 6.189320388349515 0.7447638338644241 0.3705616592284931 1.1064234596616862 1.175429078554095 1.011644937344681 0.2892876339238009 0.1315713232730282 1.0 0.2372212797486779 0.4972078859355511 0.1526461610854137 +Metal ion export 6 8 2.045760505913756 0.0407799394877477 3.779126213592233 8.553398058252426 0.5059205316086877 0.4155863674545267 2.112664358767855 1.499049247815051 1.150738830143596 0.3315496346975708 0.0670925958920387 1.0 1.0 1.0 0.0790607116166092 +Amino acid import 7 9 2.039677342688668 0.0413824730352607 3.441747572815534 8.407766990291263 0.4366482113195755 0.401453661361528 1.9997584452111057 1.165331680805512 1.104576970757323 0.3040222614424157 0.3808320474772019 1.0 1.0 0.5094216597603356 0.4145551447304083 +Tetrapyrrole biosynthetic process 5 14 2.034197618026837 0.0419316746271096 3.978155339805826 12.308252427184469 0.3532525135599431 0.4350645652075638 2.0813570291196224 1.845916473083467 1.0884111669512433 0.3019410049691661 0.001099560878144 1.0 0.2297987482657219 0.0038040834633598 0.0015706126808535 +Regulation of protein catabolic process in the vacuole 2 5 2.0314718419828366 0.0422071531174803 1.2014563106796117 3.3762135922330097 0.3553822840909967 0.3561494889357127 1.140898051797836 1.3189129213804007 1.3434272672921512 0.3030873575434169 0.3997040719021639 1.0 1.0 0.2365379696877526 0.0968157430558884 +Negative regulation of axonogenesis 0 5 2.030958909838908 0.0422591630283117 1.4951456310679612 5.604368932038835 0.5111440741336667 0.4854399038461674 1.2969253139844743 1.1453919241926127 0.8397552514706781 0.2885954943863668 0.7517071023139151 1.0 0.2518545844225215 0.5213399099817488 0.7757910097923159 +Response to endoplasmic reticulum stress 28 87 2.024361103741832 0.042933010783194 20.766990291262136 81.87135922330097 0.3895578367391949 0.6272162805638101 7.658618957730667 6.11384352257493 0.925049322897134 0.3624458148773257 0.001814781744773 0.249749131632643 0.5763684861057579 0.5352699234020144 0.0017021447075236 +Vesicle organization 32 101 2.0230642172405315 0.0430665271502528 22.83495145631068 92.86893203883496 0.0463488900678319 0.7096208745167389 8.867796091584163 11.766015972671791 0.8083581851270146 0.3222323416126856 0.0810226984364433 0.6911526504753159 0.6779430903140499 0.3670402756250157 0.0067754659120658 +O glycan processing 4 7 2.0166797252823887 0.0437289470770589 1.8762135922330097 5.029126213592233 0.779006640385936 0.3319918611732407 1.1540209287066336 1.1758600296433448 1.0243123329907684 0.2736840802111854 0.2970960078884674 1.0 1.0 0.4452488918515388 0.32624452618512 +Cellular transition metal ion homeostasis 10 23 2.011433542210072 0.044279683397717 5.893203883495145 20.42233009708738 0.9608801516152976 0.3243056832171095 2.800529150274697 2.6932649561537056 1.130076157725316 0.3011842711337114 0.0270687592516331 0.2695684389372801 0.1290920553826253 0.2083714330221484 0.012915229181212 +Regulation of t cell apoptotic process 0 5 2.0111958883829884 0.0443047699094196 1.1868932038834952 3.8932038834951457 0.4503832314353733 0.423725835599417 0.9611497252872896 1.2398138081259902 1.1590426056493326 0.321330197772498 0.4777516514318264 0.0652597674910206 0.1265462710440741 0.290751966651369 0.5020158400168588 +Positive regulation of mitochondrial calcium ion concentration 3 7 2.0108435294647427 0.0443419866560597 2.228155339805826 5.211165048543689 0.1418363032358024 0.4109308835680456 1.2312214690975103 1.149745265979588 1.1823006355769805 0.3144055905104015 0.0087377942346259 1.0 1.0 0.2175647207167039 0.0009118158302113 +Sterol metabolic process 19 42 2.010324086672314 0.0443968991962366 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 0.000420181550008 1.0 0.1967082241040804 0.150785190751036 5.3235976749312936e-05 +Regulation of lipase activity 3 11 2.008819132649628 0.0445563184477482 3.262135922330097 11.20873786407767 0.5080857493577803 0.3640362286084045 2.107366483573331 1.390020380944142 1.1722840995258883 0.3007278087276755 0.2713634391557862 1.0 1.0 0.2526409373615763 0.1274755097437061 +Positive regulation of toll like receptor signaling pathway 0 5 2.00166510535362 0.0453207617404933 1.2936893203883495 5.031553398058253 1.0578528534380236 0.3141679357263049 1.0138166762254122 0.5543075051408229 0.7960587950562075 0.2703423316965778 0.5240718508484606 1.0 0.1432798584585485 0.3247468214281712 0.5492603500015365 +Ubiquitin dependent erad pathway 15 35 1.9995855309558397 0.0455450376184027 8.635922330097088 33.189320388349515 0.3115013568224312 0.6374197165259132 3.8558329126504 3.468034686486237 0.8005779700625321 0.3301326985720395 0.0023778042077325 0.310874529382391 0.5259644699110895 0.5603186564401545 0.0039060207753922 +Regulation of membrane lipid distribution 3 7 1.988930482443027 0.0467088766490697 2.2475728155339807 5.5 0.9490281853542848 0.2470521989607894 1.5110816970578842 2.070950253254846 1.235309366119274 0.2447223644308076 0.1213295447049722 1.0 1.0 0.1383652025719425 0.1410707299584872 +Cellular response to sterol depletion 3 6 1.984823776319096 0.0471640812141791 1.5388349514563109 5.174757281553398 -0.0357410463294858 0.4492159343011578 1.2349861844051535 0.9697080379948562 1.1022855471720296 0.3110213130652335 0.1459993121590467 1.0 1.0 1.0 0.1630814235328921 +Response to sterol depletion 3 6 1.984823776319096 0.0471640812141791 1.672330097087379 5.589805825242719 -0.0583638840374338 0.4573932864125807 1.3408848722207571 1.1295642948839812 1.0942610844225364 0.3128726073787699 0.1784863028688835 1.0 1.0 1.0 0.1985866733922443 +Regulation of amyloid precursor protein catabolic process 3 14 1.980097357013036 0.0476925900916098 3.8859223300970873 14.189320388349516 0.723751929535891 0.4024575578925681 1.8731873759514015 2.0164571748807374 0.9921534445034136 0.3036488689822377 0.0549254295812836 0.0102371045657047 0.0034893000144238 0.0070923684446229 0.0674365169251515 +Glycerolipid biosynthetic process 20 51 1.975373894736869 0.0482257330451609 13.466019417475728 44.71844660194175 0.9430872689732808 0.3767257192898063 6.88753698417372 8.249645447783736 1.3199493331746477 0.3584243730449019 0.0675676498560967 1.0 1.0 0.6430239593297481 0.0572216756934203 +Receptor recycling 3 8 1.9751533395072456 0.0482507492451027 1.83252427184466 7.075242718446602 0.2017018942761934 0.4536082228606722 1.6905248328776263 1.154000508707628 1.0635166063679875 0.2938337757297349 0.111398140820949 1.0 1.0 0.1300982938321277 0.1298078118605267 +Metal ion transport 32 109 1.971332944988036 0.0486858054073902 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.0714400774645465 0.5023005139274972 0.4311900580775072 0.6108815714978303 0.0818329585001369 +Leukocyte migration 12 53 1.967436523500834 0.0491329071567951 10.118932038834952 46.80582524271845 0.3575882448711393 0.6313812887885496 4.534434682359551 5.391125848207169 0.8213013384586727 0.3308801783294869 0.4279544463303971 0.1403881914917208 0.3803883597337516 0.1154859850799389 0.3477189954247736 +Aminoglycan metabolic process 10 18 1.9635319245901144 0.049584398723339 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 0.1488019251138877 1.0 0.4515227909961177 0.1896820159952031 0.1816410943481965 +Regulation of autophagy 23 96 1.9600995403012225 0.0499841569729164 20.118932038834952 94.3495145631068 0.711099590941891 0.531831837860264 6.9602150135047 11.998348379757145 0.9791686068293384 0.3767967479294735 0.0403651874449576 0.3774217541644473 0.2655243330236689 0.0330266940709459 0.0067670833059855 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d40fd38dc8175e9e402e234ac08c5819eec77984 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 6528, + "title": "Average number of proteins per term", + "value": 19.962009803921568 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c6c6f386d3d06e2716bac17c753c199a18715096 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2b4c0decb9da58d753ede73ff2776b848acd0f2c --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1580 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrion organization 0.6249747528909904 5.7792794106020455 7.502124550181805e-09 4.8972670053460584e-05 4.897386907011482e-05 212 Q8N183,P04062,Q86Y39,Q8N4H5,Q8TB36,Q9BRT2,Q96A26,Q99595,Q9NS69,Q9NX14,Q9Y2R0,Q9Y584,Q9Y6M9,Q69YU5,P52789,Q5XKP0,O43676,Q9Y276,Q9Y512,O60830,P14406,P45880,Q13505,P21796,Q9BUR5,Q9UDX5,Q9BWH2,Q9Y5J7,Q96I36,O95167,O75431,Q8N8Q8,Q15070,Q9BSK2,Q9NW81,P27544,Q9Y241,O14925,Q99623,O96000,Q9Y5J9,Q9H061,Q6UXV4,P12235,O00165,O60313,Q9H4A6,P03886,Q9Y6C9,Q15388,Q9H3K2,Q96DA6,Q8IUX1,Q8N5K1,Q9Y371,P49257,Q9GZY4,Q16891,O14548,O43819,Q9NVI7,O95202,Q5HYI7,Q96CU9,Q9P0J0,P30536,Q96RL7,Q9UG56,Q53H12,Q8IWA4,O75880,Q9Y3D6,Q8WWC4,O43615,O95168,Q9H300,Q6DKK2,Q10713,Q9BUB7,Q3ZCQ8,O95139,O14737,P51572,P05141,Q5T9A4,Q9NQ11,P03915,P78310,Q9NX63,P35232,O96008,O95140,Q7L592,Q9Y375 94 +Membrane organization 0.5682229023244385 5.264958084334567 1.402213459844062e-07 0.0009149461920185 0.0004576824732963 242 Q4KMQ2,Q8N6H7,Q8N4V1,Q96A33,Q9NQC3,Q9NS69,Q9NZD2,Q9P2W9,Q9Y584,O43633,P52789,Q5XKP0,P62820,Q9Y276,Q9Y512,Q5J8M3,O95249,P45880,Q13505,O14657,Q9BUR5,O60499,Q6NUK4,Q9Y5J7,O75844,Q96CP7,O75431,P50897,Q8N8Q8,P50402,Q9NPA0,Q15070,Q9BSR8,Q9Y5J9,Q12981,Q9NR31,P49069,P49755,Q6UXV4,Q96AA3,P12235,P56962,Q8NHH9,Q9NZJ7,O60313,Q00765,Q9H4A6,Q15041,Q9H6H4,O94901,Q9H3K2,Q15392,Q9Y371,O43760,P16615,Q16891,O43681,Q15363,O95202,Q5HYI7,Q9P0J0,Q96GC9,Q9BZG1,P30536,Q53H12,Q13190,Q8IWA4,Q8WWC4,Q15006,Q9UEU0,Q9Y2U8,O15400,P51790,P57088,O95721,Q3ZCQ8,O14737,Q8N766,Q15629,O15258,P05141,Q86XL3,O15155,O75396,Q9NQ11,Q9NX63,Q8NFQ8,O43752,Q9UNK0,O15118,O95140,Q5JRA6,P98194 93 +Transmembrane transport 0.5643622979133889 5.123137224558237 3.004934916698419e-07 0.0019596990857187 0.0006538738378757 231 P04062,P28288,Q4KMQ2,Q8N4V1,P05067,Q99595,Q9NWR8,Q9NS69,Q9UDW1,Q9Y584,P52789,P13073,P53007,O60830,O75298,Q9UJS0,P00846,P45880,Q15043,P21796,P36383,Q9Y277,P20674,Q96H78,Q9NRA0,Q02978,O75844,O75964,P00403,Q9Y619,P24539,Q9UHG3,Q8N1S5,P27105,Q9BSK2,O75746,P05556,Q9BQT8,P08195,O14925,Q99623,Q9UJZ1,O43808,Q03518,L0R6Q1,P49755,O75947,Q8TB61,Q96AQ8,P12235,Q9HD47,Q9C0H2,Q9Y6M7,Q70HW3,O75027,O75915,Q9UGP8,Q15041,Q9UBX3,O60831,Q96NB2,Q15388,Q96DA6,Q9H2D1,P06576,Q07820,P36543,Q8NEW0,P36542,Q9H0U3,Q16539,Q15758,P56385,P60468,P11166,P50416,P16615,Q99442,Q9BPX6,O14548,Q99797,P23786,P33121,Q96ER9,P47985,O95202,Q6PML9,P12236,Q7KZN9,Q96GC9,P35670,Q03519,Q9HD20,Q6NUK1,Q9UM00,Q6P4A7,Q8WWC4,O75381,O43615,O00400,Q8TBP6,Q9HC21,P51790,Q14728,Q3ZCQ8,P05023,Q15629,Q13423,P30825,Q6NXT4,P05141,Q9NQ11,Q8IYU8,Q8NE01,P03915,P08574,O96008,P98194 118 +Mitochondrial transport 0.6428074612296244 4.824277749694426 1.405114986104284e-06 0.0091306571357125 0.0022931476573238 94 Q8N4H5,Q8TB36,O14925,P49257,P56385,Q99595,Q9Y5J9,P50416,Q9H300,Q9NS69,Q9Y584,P23786,Q10713,P52789,Q9Y276,Q9Y512,O60830,Q3ZCQ8,Q9P0J0,Q9UJS0,P00846,O14737,P45880,P12235,P30536,O00165,P51572,P05141,Q53H12,Q9Y5J7,O75964,Q9UBX3,Q6NUK1,Q15388,Q9Y3D6,P24539,O75431,Q8WWC4,O96008,Q96DA6,O95140,Q8N8Q8,P06576,O43615,Q15070,Q9Y371 46 +Mitochondrial transmembrane transport 0.6966427353599312 4.767310412992952 1.8670154222633073e-06 0.012113916570121 0.0024375753353082 55 O75746,Q9BQT8,O14925,P56385,Q99595,P50416,Q9NWR8,Q9UJZ1,P23786,P53007,O60830,Q96ER9,O95202,Q3ZCQ8,Q9UJS0,P00846,P12236,P21796,Q96AQ8,P12235,P05141,O75027,Q8IYU8,O75964,Q9Y619,Q6P4A7,Q15388,P24539,O96008,Q8WWC4,Q96DA6,Q9H2D1,P06576,O43615,Q9BSK2 35 +Mitochondrial respiratory chain complex assembly 0.7141369132021512 4.653306966653274 3.2665339866344567e-06 0.0210982203364086 0.0030462762663937 51 Q8N183,Q86Y39,O95168,Q9NW81,Q9BRT2,O96000,Q9GZY4,Q9NX14,Q9H061,Q9Y2R0,O43819,Q6DKK2,Q9Y6M9,Q69YU5,O43676,Q9Y276,Q9Y512,Q96CU9,Q9P0J0,O95139,P03886,Q96I36,P03915,O95167,O75880,Q8N8Q8,Q7L592,Q8IUX1,Q15070,Q9Y375,Q9BSK2 31 +Mitochondrial membrane organization 0.7164643357602674 4.6125496729398545 3.977594474902091e-06 0.0256315762322799 0.0032457170915209 50 Q9Y5J9,Q9NS69,Q16891,Q9Y584,P52789,Q5XKP0,Q9Y276,Q9Y512,O95202,Q3ZCQ8,Q5HYI7,Q9P0J0,O14737,P45880,Q13505,Q6UXV4,P12235,Q9BUR5,P05141,O60313,Q53H12,Q8IWA4,Q9Y5J7,Q9NX63,Q8WWC4,O75431,Q9H3K2,O95140,Q8N8Q8,Q15070 30 +Endoplasmic reticulum organization 0.7058199998808701 4.587594658341931 4.48382142503867e-06 0.0288462214232455 0.0032522651402954 51 Q8N4V1,P49257,Q96A33,Q9NQC3,P57088,Q9P2W9,Q12981,O43681,Q15363,O95197,P49069,Q8N766,Q15629,O14657,Q8NHH9,Q00765,Q6NUK4,P61026,Q15041,Q9H6H4,Q8NFQ8,Q8N5M9,Q15006,Q9NPA0,Q5JRA6,Q96HR9 26 +Ion transmembrane transport 0.5413226046740097 4.542042833290425 5.5711717610318345e-06 0.0357153140216667 0.0036368609256022 169 O75746,Q4KMQ2,Q8N4V1,P05556,Q9BQT8,Q9HC21,Q99623,P51790,Q14728,P05067,P56385,Q9NWR8,P16615,Q9UDW1,O14548,P13073,P53007,Q96ER9,O43808,O95202,Q9UJS0,P00846,P12236,P45880,Q7KZN9,Q15043,P21796,P36383,Q8TB61,Q96GC9,Q96AQ8,P05023,Q9Y277,P12235,P30825,Q13423,Q9HD47,Q9C0H2,P20674,P35670,Q6NXT4,P05141,Q70HW3,Q9NQ11,Q9NRA0,O75027,Q8IYU8,Q02978,Q9HD20,O75844,P03915,P08574,O75964,Q9UBX3,P00403,Q15041,O60831,Q9Y619,Q9UM00,Q6P4A7,P24539,Q8WWC4,Q9UHG3,Q8N1S5,Q9H2D1,P06576,P27105,P98194,O00400,Q8NEW0,Q9H0U3 71 +Anion transport 0.6246442250060005 4.423759303051307 9.699808465768456e-06 0.0613575566205878 0.0056668490950647 73 O75746,P28288,Q4KMQ2,P05556,Q9BQT8,Q9HC21,P51790,Q14728,Q9NZD2,P14174,O43681,P53007,O43808,Q9UJS0,Q15907,P07602,P12236,P45880,Q15043,Q8TB61,P21796,P12235,P30536,P30825,Q9Y277,Q9C0H2,Q9NZJ7,Q08722,P05141,Q96S66,Q02978,Q15041,Q6NUK1,Q9UBX3,O60831,Q9Y619,Q9UHG3,Q9H2D1,O00400 39 +Nitrogen compound transport 0.3946967566448528 4.405586523798354 1.0549803044712648e-05 0.066551491892216 0.0056668490950647 621 Q8N183,Q8N4H5,Q8N6H7,Q8TB36,Q9BRT2,Q9Y3B3,Q99595,Q9NS69,Q9NZD2,Q9P2W9,Q9Y584,O43633,P62820,O60830,O75298,Q9Y276,Q9Y512,O95249,Q92544,Q9UJS0,Q9Y5L4,P18031,P43307,P41208,P20340,Q9BTX1,Q5BJH7,Q92783,Q9Y277,Q8TEX9,Q9Y282,Q9Y5M8,O00560,P57105,Q16850,O60499,O15173,Q96H78,Q9Y5J7,O60749,Q969Q5,P10619,Q96PC5,Q9Y619,Q9H0U4,Q9P253,Q9Y3E0,P50897,Q9UHQ4,Q8N8Q8,Q12893,Q8N5M9,P50402,P27105,Q15904,Q15070,Q9UNH7,Q15005,Q9BSK2,O75746,Q92973,P46379,P05556,P08195,O14925,Q99623,O95070,Q9Y5J9,O95235,P56589,Q7Z3B4,Q9NV70,O60725,Q9Y3E7,Q9HCU5,Q9Y3A6,Q9UID3,Q9NR31,P24390,O43808,Q5VWJ9,Q9Y679,Q15907,P07602,L0R6Q1,P49755,Q12846,Q03518,Q8TB61,P12235,P56962,Q9HD47,Q9NZJ7,Q08722,O00165,P60033,Q9H4A6,O75027,P13473,Q15041,O60831,Q15388,Q96DA6,Q9UBV2,Q9H2D1,Q07820,Q9UBQ0,Q9Y371,O15260,P40855,Q9GZP9,P49257,P50416,Q99584,O43681,Q15363,P27824,Q5HYI7,Q9P0J0,P12236,Q14108,Q7Z4Q2,Q96GC9,P52292,Q9BZG1,P30536,Q03519,Q96RL7,Q53H12,Q13190,Q9HD20,P61026,Q6NUK1,O95391,Q6P4A7,Q9BUN8,Q9Y3D6,Q8WWC4,Q9UNL2,O75381,O43615,O00400,Q9UEU0,O15400,Q9HC21,Q9Y5U9,Q7Z7H5,Q9H300,Q10713,O15127,O95721,Q3ZCQ8,Q96ED9,O14737,Q96KC8,Q15629,P30825,P51572,P05141,O15155,O75396,P49458,Q15154,Q9NQ11,Q8NFH5,Q8NBM4,Q9H9E3,O43752,O96008,P61019,Q9UNK0,O95140,Q96CS3,Q5JRA6,P98194 175 +Ion transport 0.516848102777499 4.390960860171912 1.1285085514067816e-05 0.0710212866311418 0.0056668490950647 220 P28288,Q4KMQ2,Q8N4V1,P05067,Q9NWR8,Q9NZD2,Q9UDW1,P14174,P13073,P53007,Q9UJS0,P00846,P45880,Q15043,P21796,P36383,Q9Y277,P20674,O15173,Q9NRA0,Q02978,O75844,O75964,P00403,Q9Y619,P24539,Q9UHG3,Q8N1S5,P27105,Q9UNH7,O75746,P05556,Q9BQT8,Q99623,O43808,Q15907,P07602,Q8TB61,Q96AQ8,P12235,Q9HD47,Q9C0H2,Q9NZJ7,Q08722,Q70HW3,Q96S66,O75027,Q15041,Q9UBX3,O60831,Q9H2D1,P06576,Q8NEW0,Q9H0U3,P56385,P16615,O14548,O43681,Q96ER9,O95202,P12236,Q7KZN9,Q96GC9,P30536,P35670,Q9HD20,Q6NUK1,Q9UM00,Q6P4A7,Q8WWC4,O00400,Q9HC21,P51790,Q14728,O76024,P05023,Q13423,P30825,Q6NXT4,P05141,Q9NQ11,Q8IYU8,Q8NE01,P03915,P08574,O96008,P98194 87 +Protein localization to mitochondrion 0.619939235724612 4.360736438820201 1.2962542789818343e-05 0.0811386401300646 0.00604424852371 70 Q8N4H5,Q8TB36,O14925,P49257,Q99595,Q9Y5J9,Q9H300,Q9NS69,Q9Y584,Q10713,P52789,Q9Y276,Q9Y512,O60830,Q3ZCQ8,Q9P0J0,O14737,P30536,P51572,O00165,Q53H12,Q9Y5J7,Q9Y6C9,Q15388,Q9Y3D6,Q8WWC4,O96008,Q96DA6,O95140,Q8N8Q8,O43615,Q15070,Q9Y371 33 +Organic anion transport 0.6806496360141662 4.273797278459606 1.921717708674997e-05 0.117900958590953 0.0060863526310087 49 O75746,Q99808,P28288,Q96QD8,P05556,P08195,Q9HC21,Q9BQT8,Q15758,Q14728,P11166,Q9NZD2,Q9H9B4,P14174,P53007,O43808,Q9UJS0,P07602,P12236,Q8TB61,P12235,P30825,Q9NZJ7,Q08722,P05141,Q9Y6M7,O75915,Q02978,P55011,Q15041,Q6NUK1,O60831,Q9UBX3,Q9Y619,Q96NB2,O00400,Q9H2D1,Q9H936 38 +Protein targeting to mitochondrion 0.6269459649214977 4.240420766242433 2.2310117880453006e-05 0.1355329370963907 0.0060863526310087 56 Q8N4H5,Q8TB36,O14925,P49257,Q99595,Q9Y5J9,Q9H300,Q9NS69,Q9Y584,Q10713,O60830,Q9Y512,Q3ZCQ8,Q9P0J0,O14737,P30536,P51572,O00165,Q53H12,Q9Y5J7,Q15388,Q9Y3D6,O96008,Q96DA6,O95140,O43615,Q9Y371 27 +Oxidative phosphorylation 0.6020566461020167 4.192359754203861 2.760677488700125e-05 0.1649131220659024 0.0060863526310087 70 O14949,O95168,Q9BRT2,P56385,O96000,O14548,Q9UDW1,Q9UJZ1,Q9Y6M9,P13073,O43676,P22695,O95139,P00846,P14406,Q7KZN9,O75947,P09622,O43674,P56556,O95169,P20674,P03886,P03915,P08574,O75964,O95167,P00403,P14927,P24539,Q9H3K2,Q9UI09,P06576,O75208,Q9Y375,Q9BSK2 36 +Endomembrane system organization 0.5117001603797532 4.189177645176977 2.7996717366196577e-05 0.1670362285271478 0.0060863526310087 188 O15260,Q4KMQ2,Q8N4V1,P49257,Q96A33,Q9Y3B3,Q7Z3D4,P51790,Q7Z7H5,Q9NQC3,O43760,P16615,Q9P2W9,P57088,Q12981,Q6IAA8,O43633,Q9Y3A6,O43681,Q15363,P62820,O95721,O95197,P49069,Q96ED9,Q8N766,P49755,Q14108,Q96GC9,Q8TBA6,Q15629,O14657,P56962,Q8NHH9,Q86XL3,Q00765,O15155,Q6NUK4,O75396,Q13190,Q9H4A6,O75844,P61026,Q15041,Q9H6H4,Q9H9E3,Q96CP7,Q8NFQ8,O94901,O43752,P61019,Q8N5M9,Q15006,P50402,Q9NPA0,Q5JRA6,Q96HR9,Q9UEU0,Q9BSR8,Q9Y2U8,Q9Y371 61 +Protein targeting 0.5269819599375726 4.111421124927464 3.9323121307388575e-05 0.2264046789760957 0.0060863526310087 122 P40855,P46379,Q8N4H5,Q8TB36,O14925,P49257,Q99595,Q9Y5J9,P56589,Q9H300,Q9NS69,O60725,Q9Y584,O43681,Q10713,O60830,Q9Y512,Q3ZCQ8,Q9P0J0,Q9Y5L4,O14737,Q14108,P43307,Q5BJH7,Q15629,P30536,O00560,Q9Y5M8,P57105,O00165,Q96RL7,P51572,Q53H12,P49458,Q9Y5J7,P13473,Q15041,Q15388,Q9Y3D6,O96008,Q96DA6,Q9UNL2,O95140,O75381,O43615,P27105,Q15005,Q9Y371 48 +Establishment of protein localization 0.3923334382618014 4.103312325651653 4.0727684697872135e-05 0.2334656288526599 0.0060863526310087 565 Q8N183,Q8N4H5,Q8N4V1,Q8N6H7,Q8TB36,Q9BRT2,Q96A33,Q9Y3B3,Q99595,Q9NS69,Q9P2W9,Q9Y584,O43633,P52789,P62820,O60830,O75298,Q9Y276,Q9Y512,O95249,Q5J8M3,Q92544,Q9Y5L4,P18031,P43307,P41208,P20340,Q9BTX1,Q5BJH7,Q92783,Q8TEX9,Q9Y282,Q9Y5M8,O00560,P57105,Q16850,O60499,Q9Y5J7,O60749,Q969Q5,P10619,Q96PC5,Q9H0U4,Q9P253,Q9Y3E0,P50897,Q9UHQ4,Q8N8Q8,Q12893,Q8N5M9,P50402,Q9NPA0,P27105,Q15904,Q15070,Q9NWS0,Q9UNH7,Q15005,Q92973,P46379,O14925,Q99623,O95070,Q9Y5J9,O95235,P56589,Q7Z3B4,Q9NV70,O60725,Q9Y3E7,Q9HCU5,Q9Y3A6,Q9UID3,Q9NR31,P24390,P49069,Q5VWJ9,Q9Y679,Q15907,Q12846,Q03518,P49755,P56962,Q9HD47,O00165,P60033,Q9H4A6,P13473,Q15041,O60831,Q15388,Q96DA6,Q9UBV2,Q07820,Q9UBQ0,Q9Y371,O15260,P40855,Q9GZP9,P49257,P50416,Q99584,O43681,Q15363,P27824,Q5HYI7,Q9P0J0,P11279,Q14108,Q7Z4Q2,Q96GC9,P52292,Q9BZG1,P30536,Q03519,Q96RL7,Q53H12,Q13190,Q9HD20,P61026,O95391,Q9BUN8,Q9Y3D6,Q8WWC4,Q9UNL2,O75381,Q15006,O43615,Q9UEU0,O15400,Q9Y5U9,Q7Z7H5,Q9H300,Q10713,O15127,O95721,Q3ZCQ8,Q96ED9,O14737,Q8N766,Q96KC8,Q15629,P51572,O15155,O75396,P49458,Q15154,Q9NQ11,Q8NFH5,Q8NBM4,Q9H9E3,O43752,O96008,P61019,Q9UNK0,O15118,O95140,Q96CS3,Q5JRA6,P98194,Q8NBU5 161 +Cation transmembrane transport 0.5069908571452636 4.100031288317372 4.130942848923347e-05 0.2363712362612884 0.0060863526310087 132 Q4KMQ2,Q8N4V1,P05556,P08195,Q9HC21,Q99623,Q15758,P51790,P05067,P56385,Q9NWR8,P16615,Q9BPX6,Q9UDW1,Q9UJZ1,O14548,P13073,Q96ER9,P47985,O95202,P00846,Q6PML9,Q7KZN9,Q15043,O75947,P21796,Q96GC9,Q96AQ8,P05023,P12235,Q13423,P30825,Q9HD47,P20674,P35670,Q6NXT4,P05141,Q9Y6M7,Q70HW3,Q9NQ11,Q9NRA0,O75027,Q8IYU8,Q9HD20,P03915,P08574,O75964,P00403,Q9UM00,Q9Y619,Q96NB2,P98194,Q8NEW0,P24539,Q8WWC4,Q8N1S5,P06576,P27105,P36543,O00400,P36542,Q9H0U3 62 +Membrane lipid metabolic process 0.6884845677676235 4.085705852963486 4.394302049015586e-05 0.2493879515809239 0.0060863526310087 44 Q9Y2B2,P04062,P27544,Q99735,Q96G23,Q9NZD2,O15269,O95470,Q6Y1H2,P07602,Q9H490,Q13510,Q9NWW5,Q99805,Q9NZJ7,P17900,Q53H12,Q5SGD2,Q9NRA0,O43292,Q9P035,Q96S52,P50897,Q92643 24 +Inorganic ion transmembrane transport 0.518948309532955 4.013551805079679 5.981186784986825e-05 0.3232569029026192 0.0060863526310087 122 Q4KMQ2,Q8N4V1,P05556,P08195,Q99623,P51790,P56385,Q9NWR8,P16615,Q9UDW1,O14548,P13073,Q96ER9,O95202,P00846,Q7KZN9,Q15043,P21796,Q96GC9,Q96AQ8,P05023,P12235,Q13423,Q9HD47,P20674,P35670,Q6NXT4,P05141,Q9NRA0,O75027,Q8IYU8,Q02978,Q9HD20,P03915,P08574,O75964,Q9UBX3,P00403,Q9UM00,P24539,Q8WWC4,Q9UHG3,Q8N1S5,P06576,P27105,P98194,O00400,Q9H0U3 48 +Protein insertion into membrane 0.7314095013429289 3.97156521099131 7.140194915167264e-05 0.3725733865572043 0.0060863526310087 33 Q8N4V1,Q96A33,Q9Y5J9,Q9NS69,Q9Y584,O43681,Q9Y276,Q9Y512,Q5J8M3,P49069,Q9P0J0,O14737,Q8N766,Q15629,Q53H12,Q9Y5J7,Q8WWC4,Q8N8Q8,Q15006,Q9NPA0,Q15070 21 +Intracellular transport 0.382460962287494 3.9534818798479647 7.702209933735382e-05 0.3951771228366158 0.0060863526310087 591 P28288,Q8N4H5,Q8TB36,Q9Y3B3,Q9Y366,P05067,Q99595,Q9NS69,Q9P2W9,Q9Y584,Q6IAA8,O43633,P52789,P62820,O60830,O75298,Q9Y276,Q9Y512,O95249,Q92544,P00846,Q9UJS0,Q9Y5L4,P45880,P18031,P43307,P20340,Q5BJH7,Q92783,Q8TEX9,Q9Y282,Q9Y5M8,O00560,P57105,Q15057,O60499,Q9Y5J7,O60749,O75844,Q969Q5,P10619,O75964,Q96PC5,P24539,O75431,Q9H0U4,O75503,Q9P253,Q9UHQ4,Q8N8Q8,P50402,P27105,Q15904,Q96HR9,Q15070,Q9BSR8,Q15005,Q9UNH7,Q9UH99,Q92973,P46379,O14925,Q99623,O95070,Q9Y5J9,P56589,Q9BUP3,Q7Z3B4,O60725,Q9P260,Q9UJZ1,Q9Y3E7,Q9HCU5,Q9Y3A6,Q9UID3,Q96RQ1,Q9NR31,P24390,Q9Y679,Q5SNT2,Q15907,P07602,Q12846,P49755,Q03518,Q9BVK6,O43805,P12235,P56962,Q8NHH9,Q9HD47,Q9NZJ7,O00165,P60033,O60313,Q00765,P13473,Q15041,Q9UBX3,Q15388,O94901,Q96DA6,Q9UBV2,P06576,Q9UBQ0,Q9Y371,O15260,P40855,Q9GZP9,P49257,P56385,P50416,P16615,P23786,O43681,Q15363,Q9P0J0,P11279,Q14108,Q7Z4Q2,P52292,P30536,Q03519,Q96RL7,Q53H12,Q13190,P61026,Q6NUK1,O95391,Q9BUN8,Q9Y3D6,Q8WWC4,Q9UNL2,O75381,O43615,Q9UEU0,O15400,Q9Y5U9,Q7Z7H5,Q969X5,Q9H300,P07196,Q10713,Q3ZCQ8,Q96ED9,O14737,Q15629,P51572,P05141,O15155,O75396,P49458,Q15154,Q9NQ11,Q8NFH5,Q8NBM4,O43752,O96008,P61019,Q9UNK0,O15118,O95140,Q96CS3,Q5JRA6 164 +Anion transmembrane transport 0.676830518921191 3.9516328960097296 7.76197476932694e-05 0.3975323927655496 0.0060863526310087 43 O75746,Q4KMQ2,P05556,P08195,Q9HC21,Q9BQT8,P51790,Q14728,P53007,O43808,Q9UJS0,P12236,P45880,P21796,Q8TB61,Q9Y277,P12235,P30825,P05141,Q9Y6M7,O75915,Q02978,Q15041,Q9UBX3,O60831,Q9Y619,Q9UHG3,Q9H2D1 28 +Inner mitochondrial membrane organization 0.7983198192457723 3.9390506401858585 8.180466408092002e-05 0.4137697749271362 0.0060863526310087 24 Q5XKP0,Q9NX63,Q9BUR5,Q9Y512,Q8WWC4,O75431,O95202,Q5HYI7,Q9H3K2,Q9P0J0,O60313,Q6UXV4,Q53H12,Q9Y5J9,Q13505,Q16891,Q9Y5J7,Q9Y584 18 +Membrane lipid biosynthetic process 0.746822572501128 3.8999437748476735 9.621502935286408e-05 0.4664070141815564 0.0062193282889068 27 Q9Y2B2,P04062,O95470,Q99805,P27544,Q6Y1H2,Q96G23,Q96S52,Q53H12,Q9H490,Q13510,Q5SGD2,Q9NRA0,Q92643,O43292,Q9P035,O15269 17 +Establishment of protein localization to membrane 0.5500785989977999 3.895844951668785 9.785697766417913e-05 0.4720964108503451 0.0062193282889068 96 P40855,P46379,Q8N4V1,Q96A33,Q9Y5J9,Q9NS69,O60725,Q9Y584,O43681,Q9Y276,Q9Y512,Q5J8M3,P49069,Q9P0J0,Q9Y5L4,Q15907,O14737,Q8N766,P43307,Q5BJH7,Q9BZG1,Q15629,O00560,Q53H12,P49458,Q9H4A6,Q9Y5J7,Q9HD20,P61026,Q15041,Q9Y3D6,Q8WWC4,Q9UNL2,O15118,Q8N8Q8,Q15006,Q8NBU5,Q9NPA0,P27105,P98194,Q15904,Q15070 42 +Protein transmembrane transport 0.7451249038248572 3.8631262294010544 0.0001119451240982 0.5184853761061128 0.0064625041595997 26 O60830,O75298,Q15388,O14925,Q3ZCQ8,Q96DA6,O75381,Q99595,P49755,Q9NS69,O43615,Q07820,Q9Y584,Q15629 14 +Nadh dehydrogenase complex assembly 0.6881005346932669 3.799571119984112 0.0001449467124183 0.6118179003497547 0.0064625041595997 37 Q8N183,Q86Y39,O95168,Q9NW81,O96000,Q9GZY4,Q9NX14,Q9H061,Q9Y6M9,O43676,Q9Y276,Q96CU9,Q9P0J0,O95139,P03886,P03915,O95167,Q7L592,Q8IUX1,Q15070,Q9Y375 21 +Endoplasmic reticulum to golgi vesicle mediated transport 0.5574232312468702 3.7828069618724207 0.0001550696764174 0.6366444123482942 0.0064625041595997 75 Q9Y5U9,P49257,Q9Y3B3,Q7Z7H5,O95070,Q969X5,Q9P2W9,Q9Y3A6,Q96RQ1,Q15363,P62820,Q9NR31,P24390,O95249,P49755,Q5BJH7,P56962,Q8NHH9,Q9HD47,Q9Y282,P51572,O15155,O75396,Q13190,Q96PC5,Q9H0U4,P61019,Q5JRA6,Q9BSR8 29 +Respiratory electron transport chain 0.5600141785380138 3.758527189520526 0.0001709164680172 0.6723594197978202 0.0064625041595997 60 O14949,P21912,P04062,O95168,O75746,O96000,O14548,Q9UDW1,O43819,Q9Y6M9,P13073,O43676,Q9UJS0,O95139,Q7KZN9,P09622,O43674,P56556,O95169,P20674,P03886,P03915,P08574,O95167,P00403,P14927,Q9H3K2,Q9UI09,Q9Y375 29 +Proton transmembrane transport 0.6291483600941776 3.7545269471040736 0.0001736691613449 0.6781953974761725 0.0064625041595997 47 Q99623,P51790,P56385,O14548,Q9UDW1,P13073,P00846,Q7KZN9,P05023,P12235,Q13423,P20674,P05141,P03915,O75964,P00403,P24539,P06576,O00400 19 +Regulation of t cell differentiation in thymus 0.9734151329243363 3.708133114514466 0.0002087928964695 0.7441444727088163 0.0065845411988087 2 P00813 1 +Organelle fusion 0.5702142298046158 3.665988643978325 0.0002463848589024 0.7998320538809816 0.0071875042173587 55 O15400,Q8TB36,Q9H300,Q12981,Q9UJZ1,Q9Y3E7,O95721,O95249,Q9BZG1,P56962,O60499,O60313,O15155,O75396,Q13190,Q9NQ11,Q8IWA4,Q9Y6C9,Q9NX63,Q9Y3D6,O43752,Q9P253,Q9UNK0,O95140,Q9UEU0,Q9BSR8 26 +Golgi vesicle transport 0.4750039286137244 3.657555614478184 0.0002546320214715 0.8103261956753061 0.0072905168252915 147 O15260,Q8N6H7,P49257,Q9Y5U9,Q9Y3B3,O95070,Q7Z7H5,Q969X5,Q9NV70,Q9P2W9,Q12981,Q9HCU5,Q9Y3A6,Q96RQ1,Q15363,P62820,O15127,Q9NR31,P24390,O95249,P49755,P11279,P20340,Q5BJH7,Q9BZG1,Q8TBA6,P56962,Q8NHH9,Q9HD47,Q9Y282,O15258,P51572,Q96RL7,O60499,O15155,O75396,Q13190,Q9H4A6,O60749,P61026,Q96PC5,Q9H9E3,O43752,Q9H0U4,P61019,Q9UHQ4,Q12893,Q5JRA6,P98194,Q9UEU0,Q9BSR8 51 +Regulation of mammary gland epithelial cell proliferation 0.9599766286882878 3.647545757065603 0.0002647571726186 0.8224607659812608 0.0074663339630404 2 Q9NQC3 1 +Regulation of toll like receptor 9 signaling pathway 0.991787454012662 3.6419534316988784 0.0002705770274498 0.8290810552281958 0.0074663339630404 3 Q6IC98 1 +Toll like receptor 9 signaling pathway 0.991787454012662 3.6419534316988784 0.0002705770274498 0.8290810552281958 0.0074663339630404 3 Q6IC98 1 +Organic acid transport 0.604774424694935 3.5985309460054675 0.0003200197760142 0.8762415310687858 0.0080072657986805 48 O75746,P28288,Q96QD8,P05556,P08195,Q9BQT8,Q15758,P11166,P50416,Q9H9B4,P14174,P23786,P33527,P53007,P33121,O43808,Q9UJS0,P30825,Q96H78,O75915,Q02978,P55011,Q15041,Q9UBX3,O60831,Q9Y619,Q96NB2,P31751,Q9Y3D6,Q6P4A7,O14975,Q9H2D1,Q9H936 33 +Glycoprotein biosynthetic process 0.5414728034784049 3.5815446585133457 0.0003415687355652 0.8924867948957473 0.0083025339159172 63 Q86YN1,Q7LGA3,Q9BT22,Q92542,Q2TAA5,Q8NBI6,Q4G148,P46977,Q8WVQ1,Q10472,Q96AA3,Q6ZXV5,Q99805,Q9BYC5,Q9NQX7,Q8NCH0,Q9H4A6,Q9BXS4,O60476,Q9Y673,Q9Y2C2,Q8NAT1,Q96L58,O15118,Q9P2E5,Q9H0U3 26 +Sphingolipid metabolic process 0.6707890102055953 3.573444669925028 0.0003523157156908 0.8997734580477605 0.0083969918219852 34 P04062,O95470,Q99805,P27544,Q9NZJ7,Q6Y1H2,Q96G23,P50897,P07602,P17900,Q13510,Q53H12,Q5SGD2,Q9NZD2,O15269,Q9NWW5,Q9P035 17 +Heme transport 0.9380660239555976 3.5477615789323407 0.0003885197437487 0.9208768443239572 0.00874571340411 2 O15173 1 +Iron coordination entity transport 0.9380660239555976 3.5477615789323407 0.0003885197437487 0.9208768443239572 0.00874571340411 2 O15173 1 +Cation transport 0.4665037701240389 3.5312697559273376 0.0004135697397225 0.9328174467360892 0.0090293754545436 167 Q4KMQ2,Q8N4V1,P05556,Q9HC21,Q99623,P51790,P05067,P56385,Q9NWR8,P16615,O76024,Q9UDW1,O14548,P13073,Q96ER9,O43808,O95202,P00846,Q15907,Q7KZN9,Q15043,P21796,Q96GC9,Q96AQ8,P05023,P12235,P30536,P30825,Q13423,Q9HD47,P20674,P35670,Q6NXT4,P05141,O15173,Q70HW3,Q9NQ11,Q9NRA0,O75027,Q8IYU8,Q9HD20,P03915,O75844,P08574,O75964,P00403,Q9UM00,Q9Y619,P24539,Q8WWC4,Q8N1S5,P06576,P27105,P98194,O00400,Q8NEW0,Q9UNH7,Q9H0U3 58 +Calcium ion import into sarcoplasmic reticulum 0.9193689745837028 3.4616076440385375 0.0005369593397281 0.969989621305111 0.010558043884776 2 O75844 1 +Atp synthesis coupled electron transport 0.5907533601637168 3.4325905537953365 0.0005978442001763 0.9798367575976332 0.0108562830733447 47 O14949,O95168,O96000,O14548,Q9UDW1,Q9Y6M9,P13073,O43676,O95139,Q7KZN9,P09622,O43674,P56556,O95169,P20674,P03886,P03915,P08574,O95167,P00403,P14927,Q9H3K2,Q9UI09,Q9Y375 24 +Organic acid transmembrane transport 0.6567663220815306 3.41234813065657 0.0006440580338666 0.9850906294689216 0.0112117622535513 32 O75746,P28288,Q96QD8,P05556,P08195,Q9BQT8,Q15758,P11166,P50416,Q9H9B4,P23786,P33527,P53007,P33121,Q9UJS0,P30825,O75915,Q02978,Q15041,Q9UBX3,O60831,Q9Y619,Q96NB2,P31751,Q9H2D1,Q9H936 26 +Glycoprotein metabolic process 0.5209231729435775 3.3954552660164143 0.0006851456898522 0.988600251275296 0.0116208323108107 72 Q86YN1,Q7LGA3,Q9BT22,Q92542,P62820,Q2TAA5,Q8NBI6,Q4G148,P46977,Q8WVQ1,Q9NX62,Q10472,Q96AA3,Q6ZXV5,Q99805,Q9BYC5,Q9NQX7,Q8NCH0,Q9H4A6,Q9BXS4,O60476,Q9Y673,Q9Y2C2,Q8NAT1,Q9H0U4,Q96L58,O15118,Q9P2E5,Q9UKV5,Q9H0U3 30 +Protein retention in golgi apparatus 0.904177621969036 3.390909067125909 0.000696612099347 0.9894229470089068 0.0117506040944116 2 Q9H4A6 1 +Golgi organization 0.5220628830000092 3.387433584022829 0.0007054979620979 0.9900194396528244 0.0118698213829264 63 O15260,P49257,Q7Z3D4,Q9Y3B3,Q7Z7H5,Q9P2W9,Q9Y3A6,Q15363,P49755,Q96GC9,Q8TBA6,P56962,Q8NHH9,O15155,O75396,Q13190,Q9H4A6,Q9H9E3,O43752,P61019,Q9UEU0,Q9BSR8 22 +Localization within membrane 0.4527768288146213 3.3694370981791963 0.0007532188060552 0.992692580589864 0.0121407712738984 197 P40855,P46379,O15400,Q8N4V1,P05556,Q96A33,Q9Y5J9,P56589,P35613,Q9NS69,Q7Z3B4,Q9NV70,O60725,Q9Y584,O43681,Q15363,Q9Y276,Q9Y512,Q5J8M3,P49069,Q92544,Q9P0J0,Q9Y5L4,Q15907,P07602,O14737,Q8N766,O43805,Q14118,P43307,O15321,Q9BTX1,Q5BJH7,Q9BZG1,Q15629,Q9HD47,Q99805,Q9NZJ7,O15258,O00560,Q15057,P57105,P60033,Q53H12,P49458,Q9H4A6,O00264,Q9Y5J7,Q9BXS4,Q9HD20,P61026,Q15041,Q13641,Q9Y3D6,Q8WWC4,O43752,Q9UBQ0,Q9UNL2,Q9UNK0,O15118,Q8N8Q8,Q15006,Q9HD45,Q9NPA0,Q8NBU5,P27105,P98194,Q15904,Q15070,Q9UEU0,Q9Y371 71 +Carboxylic acid transport 0.6463007327352482 3.363846980314855 0.0007686414751115 0.993392969312053 0.0122701866699073 33 O75746,P28288,Q96QD8,P05556,P08195,Q9BQT8,Q15758,Q9H9B4,P14174,P53007,Q9UJS0,P07602,P30825,Q9NZJ7,O75915,Q02978,P55011,Q15041,Q9UBX3,O60831,Q9Y619,Q96NB2,Q9H2D1,Q9H936 24 +Organophosphate ester transport 0.651134377252137 3.3440625210377615 0.0008256112910116 0.9954463063605316 0.0126265151270021 31 O00400,O43808,Q08722,Q9HC21,P05141,P12236,Q9H2D1,Q14108,Q9NZD2,Q96GC9,Q8TB61,Q6NUK1,P12235,Q9BSK2 14 +Prostate gland growth 0.9248977206312112 3.3422267841873134 0.0008310912807336 0.9956064583222296 0.0126760838332461 3 Q9NZJ7,P07602 2 +Negative regulation of leukocyte degranulation 0.8924919661116054 3.336090659526631 0.000849654510785 0.9961082731723973 0.0127800567889504 2 P09601 1 +Antigen processing and presentation of peptide antigen via mhc class ib 0.8924919661115984 3.336090659526631 0.000849654510785 0.9961082731723973 0.0127800567889504 2 Q03519 1 +Negative regulation of cytokine production involved in immune response 0.8924919661116054 3.336090659526631 0.000849654510785 0.9961082731723973 0.0127800567889504 2 P09601 1 +Intracellular protein transport 0.3907729400405146 3.327736865514743 0.0008755452267368 0.9967139295392318 0.0129710327533478 354 Q8N4H5,Q8TB36,Q9Y3B3,Q99595,Q9NS69,Q9P2W9,Q9Y584,P62820,O60830,O75298,Q9Y276,Q9Y512,Q92544,Q9Y5L4,P18031,P43307,P20340,Q5BJH7,Q92783,Q8TEX9,Q9Y282,Q9Y5M8,O00560,P57105,O60499,Q9Y5J7,O60749,Q969Q5,P10619,Q9H0U4,Q9P253,Q9UHQ4,Q8N8Q8,P50402,P27105,Q15904,Q15070,Q9UNH7,Q15005,Q92973,P46379,O14925,Q99623,Q9Y5J9,P56589,Q7Z3B4,O60725,Q9HCU5,Q9Y3A6,Q9NR31,Q9Y679,Q12846,P49755,P56962,Q9HD47,O00165,P60033,P13473,Q15041,Q15388,Q96DA6,Q9UBV2,Q9UBQ0,Q9Y371,O15260,P40855,Q9GZP9,P49257,O43681,Q15363,Q9P0J0,Q14108,Q7Z4Q2,P52292,P30536,Q96RL7,Q53H12,Q13190,O95391,Q9BUN8,Q9Y3D6,Q8WWC4,Q9UNL2,O75381,O43615,Q9UEU0,O15400,Q7Z7H5,Q9H300,Q10713,Q3ZCQ8,O14737,Q15629,P51572,P49458,Q15154,Q9NQ11,Q8NFH5,Q8NBM4,O43752,O96008,Q9UNK0,O95140,Q96CS3 104 +Actin myosin filament sliding 0.8886941279579359 3.318192138188442 0.0009060213762352 0.9973072397565446 0.0129771120154638 2 P60660 1 +Aerobic respiration 0.4982295039232227 3.3168253015845477 0.0009104652731437 0.99738430287382 0.0129771120154638 96 O14949,P21912,O95168,P56385,O96000,Q9UDW1,O14548,Q9Y6M9,P13073,O43676,P22695,P00846,O95139,P14406,Q7KZN9,Q13423,P20674,P03886,P03915,P08574,O75964,O95167,P00403,P14927,P24539,Q9H3K2,P06576,Q15070,Q9Y375,Q9BSK2 30 +Mitochondrial respirasome assembly 0.9184687317358292 3.312812468085535 0.0009236288818774 0.99759987760117 0.013136055208924 3 Q9Y241,P14406 2 +Membrane fusion 0.5633784116111485 3.286425501602919 0.0010146760970819 0.9986760933702468 0.0138126551268563 49 P56962,O95721,O15400,O43752,O95249,O60499,O15155,O75396,Q9BSR8,Q13190,Q9NQ11,Q8IWA4,Q9P2W9,Q12981,Q9UEU0,Q9BZG1 16 +Neurofilament cytoskeleton organization 0.8793456032719832 3.273959829640771 0.0010605168628556 0.999018793563748 0.0138178366048147 2 Q16352 1 +Carbohydrate derivative transport 0.7597254789932175 3.265057092223198 0.0010944201488636 0.999213790341774 0.0140360996695123 20 Q9NZJ7,O43808,Q08722,Q9HC21,P07602,L0R6Q1,P12236,Q9NZD2,O00400,Q8TB61,Q6NUK1,Q96AA3,P12235 13 +Organelle membrane fusion 0.6156713867409215 3.252588492172929 0.0011435898072118 0.9994298586071036 0.0144118808136659 37 P56962,O95721,O15400,O43752,O95249,O60499,O15155,O75396,Q9BSR8,Q13190,Q9NQ11,Q8IWA4,Q12981,Q9UEU0,Q9BZG1 15 +Regulation of systemic arterial blood pressure by hormone 0.8723342097575227 3.2406213633275796 0.0011926948976606 0.9995863784348596 0.0147181706841747 2 O75787 1 +Regulation of steroid hormone biosynthetic process 0.8702892199824712 3.2308709119415333 0.0012341366335362 0.9996845213075424 0.0150869736773866 2 P16435 1 +Regulation of hormone biosynthetic process 0.8702892199824712 3.2308709119415333 0.0012341366335362 0.9996845213075424 0.0150869736773866 2 P16435 1 +Azole transmembrane transport 0.8694127957931643 3.22668843529957 0.0012523174186753 0.9997198684698276 0.0152521046811807 2 Q9HC21 1 +Cellular respiration 0.4715725980274995 3.2209752010767168 0.0012775520215464 0.999762464017457 0.0154728378416608 112 O14949,O75746,P04062,P21912,O95168,Q9BRT2,P56385,O96000,Q9UDW1,Q9UJZ1,O14548,Q9Y6M9,O43819,P13073,O43676,P22695,Q9UJS0,P00846,O95139,P14406,Q7KZN9,O75947,P09622,O43674,Q13423,O95169,Q9NZ45,P20674,P03886,P03915,P08574,O75964,O95167,P00403,P14927,P24539,Q9H3K2,P06576,Q15070,Q9Y375,Q9BSK2 41 +Regulation of glucosylceramidase activity 0.8641542506573214 3.201546639940694 0.0013669194461123 0.999867556496163 0.0161946463597483 2 Q14108 1 +Olfactory behavior 0.8606485539000885 3.184740554475168 0.0014488383828863 0.9999224722915844 0.0167887251163394 2 O76024 1 +Chemosensory behavior 0.8606485539000885 3.184740554475168 0.0014488383828863 0.9999224722915844 0.0167887251163394 2 O76024 1 +Negative regulation of protein exit from endoplasmic reticulum 0.8603564125036567 3.1833384199895147 0.0014558734459508 0.9999259571697882 0.0167887251163394 2 Q9GZP9 1 +Positive regulation of heart rate 0.888953828170658 3.176347438760349 0.0014914221206463 0.9999413117531948 0.0169273568739281 3 P00813,P16615 2 +Activation of phospholipase c activity 0.8586035641250445 3.174920342775758 0.001498776389879 0.999944066754936 0.0169273568739281 2 Q99623 1 +Regulation of phospholipase c activity 0.8586035641250445 3.174920342775758 0.001498776389879 0.999944066754936 0.0169273568739281 2 Q99623 1 +Activation of protein kinase c activity 0.8586035641250445 3.174920342775758 0.001498776389879 0.999944066754936 0.0169273568739281 2 Q99623 1 +Negative regulation of glial cell proliferation 0.8855447085075618 3.1604315753111822 0.0015753560222617 0.9999660978814572 0.017387955842266 3 Q96G23 1 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.6311122754697872 3.1479359448284185 0.0016442772048961 0.999978396948596 0.0178094282648396 29 Q96RQ1,Q9H9E3,P24390,Q9Y282,O15258,O75396,P49755,Q969X5,Q9H4A6,P20340,Q9P2W9,Q12981 12 +Regulation of srebp signaling pathway 0.8518843120070161 3.1425670314749685 0.0016747336208926 0.9999822978765852 0.0180109737680185 2 Q15363 1 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.850715746421277 3.13692670828554 0.0017072879979538 0.9999856921311948 0.0181813638672799 2 Q8N5M9 1 +Purinergic nucleotide receptor signaling pathway 0.8495471808355352 3.131282321795796 0.0017404475755558 0.9999884813192932 0.0183548332362354 2 P00813 1 +Negative regulation of cell volume 0.8495471808355264 3.131282321795758 0.001740447575556 0.9999884813192932 0.0183548332362354 2 P51790 1 +Plasma membrane phospholipid scrambling 0.8495471808355287 3.131282321795758 0.001740447575556 0.9999884813192932 0.0183548332362354 2 Q96GC9 1 +Magnesium ion transport 0.8769258891855183 3.1200494079438466 0.001808207076698 0.9999926046615486 0.0189774530493325 3 Q8N4V1 1 +Cytochrome complex assembly 0.8255794452483393 3.1185040104894917 0.0018177166815984 0.999993050578552 0.019027936296496 15 O75880,Q15070,Q9BRT2,P53701,O43819,Q8N8Q8,Q7KZN9,Q9GZY4,Q96I36,Q9Y2R0,Q6DKK2,Q9BSK2,Q69YU5 13 +Microglia differentiation 0.8463336254747287 3.115739257624158 0.0018348443349618 0.9999937869959604 0.0190505913566842 2 P04062 1 +Organelle disassembly 0.5442682642975964 3.1147993804658354 0.00184070056868 0.9999940204540256 0.0190505913566842 49 Q96HY6,P04062,P27544,Q9Y3D6,O00165,P05141,Q99623,O95140,Q13190,Q9NQ11,Q9H300,Q9BWH2,P21796,Q86VR2,Q9Y6I9,Q8N5K1,P12235,P30536 18 +Regulation of morphogenesis of a branching structure 0.872808843950674 3.1006861782198394 0.0019307279515075 0.9999966814247148 0.019480358682289 3 Q9NQC3 1 +Sphingolipid biosynthetic process 0.7463420242727812 3.092119023947194 0.0019873314772416 0.9999977082804152 0.0198065647075317 19 O95470,P04062,Q99805,P27544,Q6Y1H2,Q96G23,Q53H12,Q13510,Q5SGD2,Q9P035,O15269 11 +Intracellular protein transmembrane transport 0.6988964129286199 3.090942625515213 0.0019952218280356 0.9999978235579324 0.0198330247778979 22 O60830,O75298,Q15388,O14925,Q3ZCQ8,Q96DA6,O75381,Q99595,O43615,Q15629 10 +Cellular macromolecule localization 0.3501381594043946 3.0779273286402793 0.0020844574047045 0.9999987859390184 0.0203014625962589 578 Q8N4H5,Q8N4V1,Q8TB36,Q96A33,Q9Y3B3,Q99595,Q9NQC3,Q9NS69,Q9P2W9,Q9Y584,Q6IAA8,Q13561,P52789,P62820,O60830,O75298,Q9Y276,Q9Y512,Q5J8M3,Q92544,Q9Y5L4,P18031,P43307,O15321,P20340,Q5BJH7,Q92783,O14657,Q8TEX9,Q9Y282,Q9Y5M8,O00560,P57105,O60499,O00264,Q9Y5J7,O60749,Q969Q5,P10619,Q9NUN5,Q9H0U4,Q9P253,Q9UHQ4,Q8N8Q8,P50402,Q9NPA0,Q9HD45,P27105,Q15904,Q15070,Q9NWS0,Q9UNH7,Q15005,Q9UH99,Q92973,P46379,O14925,Q99623,Q9Y5J9,O14773,O60725,Q9Y3A6,Q9NR31,P24390,P49069,Q15907,P49755,O43805,P56962,Q9HD47,O00165,P60033,Q9H4A6,O43292,Q9BXS4,P13473,Q9Y6C9,Q15041,Q15388,O94901,Q96DA6,Q9UBV2,Q9UBQ0,Q9Y371,O15260,P40855,Q9GZP9,P49257,P35613,O43681,Q15363,Q9P0J0,P11279,Q14108,Q14118,Q7Z4Q2,P52292,Q9BZG1,P30536,Q96RL7,Q53H12,Q13190,Q9HD20,P61026,O95391,Q9BUN8,Q9Y3D6,Q8WWC4,Q9UNL2,O75381,Q15006,O43615,Q9UEU0,Q96HY6,O15400,Q7Z7H5,Q9H300,Q10713,Q3ZCQ8,O14737,Q8N766,Q9H490,Q15629,Q99805,O15258,P51572,P49458,Q15154,Q9NQ11,Q8NFH5,Q13641,Q8NBM4,Q8NFQ8,O43752,O96008,Q9UNK0,O15118,O95140,Q96CS3,Q92643,Q5JRA6,P98194,Q8NBU5 143 +Maintenance of protein localization in endoplasmic reticulum 0.8679135008766863 3.0776002241524796 0.0020867465383103 0.9999988039837674 0.0203014625962589 3 P24390,O43292 2 +Protein retention in er lumen 0.8679135008766863 3.0776002241524796 0.0020867465383103 0.9999988039837674 0.0203014625962589 3 P24390,O43292 2 +Vacuolar proton transporting v type atpase complex assembly 0.8381536663745361 3.076035355367614 0.002097729695244 0.99999888690118 0.0203327112771925 2 Q8N511 1 +Proton transporting v type atpase complex assembly 0.8381536663745361 3.076035355367614 0.002097729695244 0.99999888690118 0.0203327112771925 2 Q8N511 1 +Nucleobase transport 0.8670368205727699 3.0734587182556425 0.0021159296061448 0.9999990118413348 0.0204029371771267 3 Q9Y277,P12235 2 +Mitochondrial adp transmembrane transport 0.8670368205727661 3.0734587182556115 0.002115929606145 0.9999990118413348 0.0204029371771267 3 P12235,P12236 2 +Regulation of perk mediated unfolded protein response 0.8358165352030409 3.0646543132725377 0.0021792172008019 0.9999993468461554 0.0206555960866968 2 P57088 1 +Av node cell to bundle of his cell communication 0.8343558282208599 3.057532752971734 0.0022316725150404 0.9999995365828916 0.0210525407199188 2 P78310 1 +Regulation of tetrapyrrole metabolic process 0.8630302519902109 3.0545035502152573 0.0022543334635154 0.9999996004398553 0.0212133697842712 3 Q9P0S9 1 +Regulation of retrograde protein transport er to cytosol 0.8606078316773778 3.0430208081424017 0.0023421613710361 0.9999997750893956 0.02184232775732 3 Q9GZP9,P51572 2 +Negative regulation of alcohol biosynthetic process 0.8282208588957111 3.0275512682601895 0.0024654388906677 0.9999998996154584 0.0224427905392609 2 O75477 1 +Negative regulation of cholesterol metabolic process 0.8282208588957111 3.0275512682601895 0.0024654388906677 0.9999998996154584 0.0224427905392609 2 O75477 1 +Protein localization to endoplasmic reticulum 0.5943286027106424 3.025279262230222 0.0024840365207428 0.9999999111187058 0.0225219311214014 35 Q96HY6,P46379,P60468,Q9NQC3,Q99442,O43681,P24390,Q15629,O15258,P51572,Q9Y5M8,P49458,O43292,P61026,Q9UGP8,Q8NBM4,Q9UNL2,Q9UHQ4,Q5JRA6,Q15005 20 +Lipid phosphorylation 0.82617586912066 3.01753187439707 0.0025484223898042 0.9999999416808516 0.0228832205785998 2 Q53H12 1 +Autophagy of mitochondrion 0.5998912438184263 3.0136083078118174 0.0025816087420345 0.9999999530664456 0.0231493706978038 33 P04062,P27544,Q9Y3D6,O00165,P05141,Q99623,O95140,Q9NQ11,Q9H300,Q9BWH2,P21796,Q8N5K1,P12235,P30536 14 +Alpha ketoglutarate transport 0.8250073035349215 3.011800744832984 0.0025970300511515 0.99999995757231 0.0231603991446955 2 Q9BQT8 1 +Succinate transmembrane transport 0.8250073035349196 3.011800744832984 0.0025970300511515 0.99999995757231 0.0231603991446955 2 Q9UBX3 1 +Oxaloacetate transport 0.8250073035349196 3.011800744832984 0.0025970300511515 0.99999995757231 0.0231603991446955 2 Q9UBX3 1 +Vacuole organization 0.4849338261011797 3.0075596894065426 0.0026335440099523 0.9999999665914094 0.0234434072451356 59 P54802,P04062,P11117,O75787,O14773,P16615,Q9Y3E7,Q6IAA8,P62820,Q5VWJ9,Q96ED9,Q14108,Q96GC9,Q9BZG1,Q9NWW5,P56962,Q8N511,O75396,Q9NQ11,Q12768,Q9H0U4,O75503,Q9P253,O95140,P50897,Q9Y371 26 +Reticulophagy 0.8823534007096185 3.006868631460014 0.0026395380400083 0.9999999678767328 0.0234434072451356 4 Q86VR2,Q9Y6I9 2 +Establishment of protein localization to mitochondrial membrane 0.7313436416555037 3.003047749771189 0.0026729048986697 0.9999999741791674 0.0235946833676109 19 Q9Y276,Q9Y512,Q8WWC4,Q9P0J0,O14737,Q8N8Q8,Q53H12,Q9Y5J9,Q9NS69,Q9Y5J7,Q15070,Q9Y584 12 +Endoplasmic reticulum membrane organization 0.895523394539423 3.001158012821461 0.0026895495995944 0.9999999768444868 0.0236303900217396 9 Q8NHH9,Q00765,Q9NQC3,Q9P2W9,Q12981,Q15041 6 +Ornithine transport 0.822085889570555 2.9974545416519622 0.0027224445761322 0.999999981330114 0.0238872556357409 2 P30825 1 +Dermatan sulfate metabolic process 0.8217937481741284 2.9960184746248935 0.0027352986129114 0.9999999828367396 0.0239036537417481 2 Q8NCH0 1 +Dermatan sulfate biosynthetic process 0.8217937481741284 2.9960184746248935 0.0027352986129114 0.9999999828367396 0.0239036537417481 2 Q8NCH0 1 +Dermatan sulfate proteoglycan metabolic process 0.8217937481741284 2.9960184746248935 0.0027352986129114 0.9999999828367396 0.0239036537417481 2 Q8NCH0 1 +Autophagosome membrane docking 0.8789827535808272 2.9912494897327315 0.0027783839500226 0.9999999870547042 0.0240770024793308 4 Q96GC9,P16615,P56962 3 +Atp metabolic process 0.4391025028404261 2.98656092297786 0.0028213461632198 0.999999990228327 0.0240770024793308 122 O14949,O75746,O95168,Q9BRT2,P05067,O96000,P56385,Q9BRR6,Q9UDW1,Q9UJZ1,O14548,Q9Y6M9,P52789,P13073,O43676,P22695,Q9UJS0,P00846,O95139,P14406,Q7KZN9,O75947,P09622,O43674,P30536,O95169,Q9NTK5,P20674,Q9NRA0,P03886,P03915,P08574,O75964,O95167,P00403,P14927,Q9Y3D6,P24539,Q9H3K2,P06576,Q9Y375,Q9BSK2 42 +Mitochondrial proton transporting atp synthase complex assembly 0.8467007418533246 2.976771875898824 0.0029130067322218 0.9999999946376252 0.024309274208883 3 Q15070 1 +Fatty acid elongation 0.8466399205457655 2.9764809126711347 0.0029157723200912 0.9999999947338454 0.024309274208883 3 Q6Y1H2 1 +Process utilizing autophagic mechanism 0.4274304493027398 2.9653117476767545 0.0030237634355576 0.9999999974033176 0.0247978991297994 167 Q96HY6,P04062,Q86UE4,P27544,Q99623,Q9H300,P16615,Q9NV70,Q9Y6I9,Q9Y3E7,O15269,O43633,Q9UID3,P52789,O95721,P62820,Q5T8D3,Q5VWJ9,P09601,P07602,P21796,Q96GC9,O15321,Q92783,P12235,P30536,P56962,Q9NZ45,Q9NZJ7,O00165,Q96RL7,P05141,O75396,Q9NQ11,Q9BWH2,Q9BXS4,P13473,O75844,Q969Q5,P10619,Q93050,Q9Y3D6,Q9H0U4,Q9P253,O15118,O95140,O14681,Q86VR2,Q07820,Q8N5K1,Q9UBQ0,Q9UEU0,Q9UNH7,Q9Y371 54 +Macroautophagy 0.457310184377027 2.963192223296382 0.0030446637077363 0.9999999977354356 0.024875550292995 107 Q96HY6,P04062,P27544,Q99623,P16615,Q9NV70,Q9Y6I9,Q9Y3E7,O15269,O43633,O95721,P62820,O95219,Q5T8D3,Q5VWJ9,Q9Y679,P09601,Q8IYI6,Q16543,P21796,Q96GC9,Q92783,P12235,P56962,P05141,Q9Y487,O75396,Q9NQ11,P13473,Q93050,Q9H0U4,P20339,O43464,O15118,O95140,O14681,Q86VR2,P36543,Q9UEU0,Q9UNH7,Q9Y5K8,Q9Y371 42 +Glycolipid transport 0.8921216248266659 2.9550475834954626 0.0031262083053824 0.9999999986723483 0.0253199600713854 5 Q9NZD2,Q96AA3,P07602 3 +Establishment of pigment granule localization 0.8410286382232522 2.9495906437408848 0.0031819521823441 0.9999999990783924 0.0256125571471551 3 Q15907,Q13561 2 +Germ cell migration 0.8115687992988632 2.9455894947177605 0.003223398830864 0.9999999992974712 0.0257278792075036 2 P78310 1 +Establishment of protein localization to organelle 0.4256994353539473 2.944821658189967 0.0032314086465325 0.999999999333374 0.02575016926237 188 Q92973,P40855,P46379,Q8N4H5,Q8TB36,O14925,Q99623,P49257,Q99595,Q9Y5J9,P56589,Q9H300,Q9NS69,Q9Y584,O43681,Q10713,P52789,Q9Y276,Q9Y512,O60830,Q3ZCQ8,Q9P0J0,Q9Y5L4,O14737,P11279,Q14108,Q7Z4Q2,P52292,Q92783,Q15629,P30536,Q9HD47,Q8TEX9,Q9Y5M8,O00165,Q96RL7,P51572,Q53H12,P49458,Q9Y5J7,Q8NFH5,P13473,P61026,Q15388,Q9Y3D6,Q8WWC4,O96008,Q96DA6,Q9UNL2,O95140,Q8N8Q8,O75381,O43615,Q15070,Q9NWS0,Q15005,Q9Y371 57 +Branched chain amino acid transport 0.8112766579024376 2.944143884646542 0.003238494020282 0.999999999363601 0.02575016926237 2 Q96H78 1 +Aromatic amino acid transport 0.8112766579024282 2.944143884646479 0.0032384940202827 0.999999999363601 0.02575016926237 2 P30825 1 +Positive regulation of mitophagy 0.8672902660041014 2.9368270523422413 0.003315889708922 0.9999999996166588 0.0261742781376597 4 P27544,P12235,P21796 3 +Adp transport 0.8672902660040993 2.9368270523422204 0.0033158897089222 0.9999999996166588 0.0261742781376597 4 O43808,P12235,P12236 3 +Protein import into peroxisome membrane 0.8080631025416392 2.928224541521143 0.0034090375296367 0.9999999997917364 0.0268122855342994 2 P40855 1 +Epithelial cell differentiation involved in prostate gland development 0.8331457442901307 2.911658369015167 0.0035951560631601 0.9999999999384682 0.0278731339433606 3 P07602 1 +Tetrapyrrole metabolic process 0.6704163266965084 2.90709061619284 0.0036480750295038 0.9999999999564964 0.0280456183925022 22 P30519,Q9NUN5,P09601,Q9P0S9,Q7KZN9,O00264,O75027,P22830 8 +Hormone metabolic process 0.5955516079835994 2.9064058171603397 0.0036560694319882 0.9999999999587164 0.0280456183925022 30 O95470,P16435,Q6NXT4,Q9Y394,Q6NUM9,Q53GQ0,O75787,Q6UX07,Q8NBQ5,Q8TC12,P42892,O75844,Q8NBN7,P05023,P30536 15 +Protein exit from endoplasmic reticulum 0.6540139279977865 2.9006050546292106 0.0037244297025107 0.9999999999736212 0.02850302121687 23 O15260,Q9HD47,Q9BUN8,Q9NR31,Q9GZP9,P51572,P60033,P49257,Q9Y679,Q92544,Q9UBV2,Q96CS3,Q9HCU5,Q8NBM4 14 +Negative regulation of steroid metabolic process 0.8284628872004691 2.889037656521415 0.0038642279597358 0.9999999999894464 0.0290953634615404 3 P05023,O75477 2 +Vesicle mediated transport 0.360081760943037 2.8854610310432127 0.0039084084458977 0.9999999999920994 0.0293238941127396 389 Q4KMQ2,Q8N6H7,Q9Y3B3,P05067,Q9P2W9,Q6IAA8,O43633,P62820,O95197,O95249,Q92544,P09601,P18031,P20340,Q5BJH7,Q92783,Q9Y282,O00560,Q15057,P57105,O60499,Q9NRA0,Q9NX40,O60749,Q96PC5,Q9UBG0,Q9NUN5,Q9H0U4,O75503,Q9P253,Q9Y3E0,P50897,Q9UHQ4,Q12893,Q8N5M9,Q15904,Q9BSR8,Q9UNH7,P05556,O95070,Q9NV70,Q12981,Q9Y3E7,Q9HCU5,Q9Y3A6,Q96RQ1,Q5VW38,Q9NR31,P24390,P49069,Q15907,P49755,P56962,Q8NHH9,Q9HD47,Q08722,P60033,Q9H4A6,Q9UBQ0,O15260,Q05086,P49257,O43760,P16615,Q9BRK5,Q99584,Q15363,P27824,P11279,Q14108,Q9BZG1,Q8TBA6,Q96RL7,Q13190,P61026,P55899,P30511,Q96JJ3,Q9UEU0,O15400,Q9Y5U9,P51790,Q7Z7H5,Q969X5,O15127,O95721,Q96ED9,O15258,P51572,O15155,O75396,Q9NQ11,Q9H9E3,O43752,P61019,Q9UNK0,O15118,Q5JRA6,P98194,Q8NBU5 100 +Selective autophagy 0.6028327372758803 2.876425935444406 0.0040220657235241 0.999999999996249 0.0298703584108824 26 Q96HY6,P27544,P05141,Q99623,O95140,Q86VR2,P21796,Q9Y6I9,O15269,P12235 10 +Mammary gland epithelial cell proliferation 0.853479355162035 2.8720572452004216 0.0040780908675126 0.999999999997402 0.0301151325600934 4 Q9NQC3 1 +Negative regulation of production of molecular mediator of immune response 0.8233320643485224 2.864178135912897 0.0041809281479332 0.999999999998676 0.0302747736521314 3 P09601 1 +Regulation of mitochondrion organization 0.5262363985461066 2.864074152646782 0.0041823009162207 0.9999999999986878 0.0302747736521314 47 P27544,Q9Y3D6,O00165,Q96A26,P05141,Q9UG56,O60313,Q9H3K2,O14737,Q9H300,Q9H4A6,P21796,Q9Y6C9,P12235,P30536 15 +Regulation of granulocyte differentiation 0.7949167397020274 2.862761080626213 0.0041996710740344 0.999999999998829 0.0302747736521314 2 O00165 1 +Steroid biosynthetic process 0.5116794455130746 2.8586572958229546 0.0042543812709876 0.999999999999182 0.0304858407651014 50 P28288,O14734,Q9UKR5,Q53GQ0,P37268,P16435,P00387,Q13510,P05023,P30536,O75477,Q16850,Q14534,O94905,O75845,Q8NBQ5,Q14739,Q15738,Q9H4L5,Q15125,Q15392,Q15800 22 +Signaling receptor ligand precursor processing 0.8499736380624456 2.8555313987686106 0.0042964874326327 0.9999999999993792 0.0306056106218523 4 O75787,P42892 2 +Phosphatidylglycerol acyl chain remodeling 0.821157218001175 2.8536169748948694 0.0043224611420993 0.9999999999994764 0.0306056106218523 3 Q8NF37,Q92604 2 +Male meiotic nuclear division 0.8190243570537192 2.8432459199809847 0.0044656599164325 0.9999999999997952 0.0310456101538569 3 Q9Y2W6 1 +Negative regulation of receptor binding 0.785860356412514 2.8173440087117423 0.0048422630197095 0.9999999999999828 0.03272287059282 2 P16615 1 +Mitochondrial electron transport cytochrome c to oxygen 0.8738504282983701 2.815069683211287 0.0048766658365402 0.9999999999999862 0.0328839995363433 7 P13073,O14548,P20674,P00403 4 +Cellular response to low density lipoprotein particle stimulus 0.8118059614260642 2.8080447538534843 0.0049843299464236 0.9999999999999932 0.0334062688811636 3 P60033,O15118 2 +Positive regulation of protein exit from endoplasmic reticulum 0.8386436714411083 2.801884761311209 0.0050805017974513 0.9999999999999964 0.0338769312908706 4 P60033,Q9NR31,P51572 3 +Amino acid transport 0.6974264625358201 2.7980211155974315 0.005141675119177 0.9999999999999976 0.034110625180882 19 O75746,P30825,Q9Y619,Q96QD8,Q96NB2,Q6P4A7,P05556,P08195,Q15758,Q9UJS0,Q96H78,O75915,Q9H936,P55011,Q15041,O60831 16 +Copper ion transport 0.8089724710375521 2.7941838925289058 0.0052030881750251 0.9999999999999984 0.0343088480874384 3 Q8N4V1 1 +Phosphatidylinositol acyl chain remodeling 0.8077147866744663 2.788023739209603 0.0053030657663308 0.9999999999999992 0.0347355660987684 3 Q96N66,Q92604 2 +Protein localization to basolateral plasma membrane 0.7800175284837949 2.7879026105918396 0.0053050489277683 0.9999999999999992 0.0347355660987684 2 P61026 1 +Glycosylation 0.4944450150970733 2.7857751135570132 0.0053399904534179 0.9999999999999992 0.0349084268918279 52 P04062,Q86YN1,Q9BT22,Q8NBI6,Q2TAA5,Q4G148,P46977,Q10472,Q96AA3,Q6ZXV5,Q9BYC5,Q9BXS4,O60476,Q9Y673,Q9H9E3,Q8NAT1,Q96L58,O15118,Q9H0U3 19 +Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process 0.7773882559158775 2.7746179033943568 0.0055266597264878 0.9999999999999998 0.0356150043799274 2 Q7LGA3 1 +Sulfation 0.7773882559158649 2.7746179033942915 0.0055266597264889 0.9999999999999998 0.0356150043799274 2 Q9Y2C2 1 +Endoplasmic reticulum tubular network organization 0.8284882234267893 2.7713489633341184 0.0055824563934478 1.0 0.0356569737525542 11 Q9H6H4,Q8NHH9,O95197,Q6NUK4,Q9NQC3,P61026,Q15041 7 +Chromosome attachment to the nuclear envelope 0.776511831726568 2.77018467397218 0.0056024517651713 1.0 0.0356807854858914 2 O94901 1 +Respiratory chain complex iv assembly 0.8465109026868676 2.769136400719083 0.0056205099453086 1.0 0.0357609053830161 9 Q15070,O43819,Q8N8Q8,Q7KZN9,Q9GZY4,Q96I36,Q9Y2R0 7 +Nucleotide transport 0.7594020621078815 2.7623914475595197 0.0057379638591599 1.0 0.0363311620490746 15 O43808,Q08722,Q9HC21,P12236,Q9H2D1,Q8TB61,O00400,Q6NUK1,P12235,Q9BSK2 10 +Synaptic membrane adhesion 0.7741747005550672 2.758350495625214 0.0058093872037798 1.0 0.0366766727913685 2 P10586 1 +Mitochondrial protein catabolic process 0.7724218521764633 2.7494631633558506 0.0059692971952833 1.0 0.0372538930122465 2 Q9UG56 1 +Atp transport 0.867797601637918 2.7483608554632912 0.0059894050738467 1.0 0.0373436832111473 6 O43808,Q08722,P12236,Q6NUK1,P12235 5 +Protein import into mitochondrial matrix 0.8323614361024319 2.7445076007561444 0.0060601751076028 1.0 0.0374274579966236 10 O60830,Q15388,Q3ZCQ8,O14925,Q96DA6,Q99595,O43615 7 +Response to thyroglobulin triiodothyronine 0.7709611451942731 2.7420493778360124 0.006105716235758 1.0 0.0375665556899421 2 P16278 1 +Pyrimidine containing compound transmembrane transport 0.7981132555509458 2.7408361577676303 0.0061283058022436 1.0 0.0376700379256559 3 Q9BSK2 1 +Dna methylation involved in gamete generation 0.769792579608535 2.7361133175862284 0.006216961329001 1.0 0.0381073460617079 2 Q9Y2W6 1 +Cellular response to manganese ion 0.7955948074960222 2.7284122026789603 0.0063640028671159 1.0 0.038826365155638 3 Q9NQ11 1 +Electron transport chain 0.4567017021084743 2.716350920774818 0.0066005914235165 1.0 0.0398306459774169 78 O14949,P21912,P04062,O95168,O96000,O14548,Q9UDW1,O43819,Q9Y6M9,P13073,O43676,P16435,Q9P0J0,Q9UJS0,O95139,Q7KZN9,P20674,P03886,P03915,P08574,O95167,P00403,P14927,Q9H3K2,Q9Y375 25 +Protein localization to organelle 0.3635220480513584 2.71404465741215 0.0066467205446072 1.0 0.0399472427241616 341 Q8N4H5,Q8N4V1,Q8TB36,Q96A33,Q99595,Q9NQC3,Q9NS69,Q9Y584,Q13561,P52789,O60830,Q9Y276,Q9Y512,Q5J8M3,Q9Y5L4,P20340,Q92783,O14657,Q9Y5M8,Q9Y5J7,Q9NUN5,Q8N8Q8,Q9NPA0,Q15070,Q15005,O14925,Q99623,Q9Y5J9,O14773,P24390,P49069,P49755,Q9HD47,O00165,P60033,Q9H4A6,O43292,P13473,Q9Y6C9,Q15388,O94901,Q96DA6,Q9Y371,P40855,P49257,O43681,Q9P0J0,P11279,Q14108,Q14118,Q7Z4Q2,P52292,P30536,Q96RL7,Q53H12,P61026,Q9Y3D6,Q8WWC4,Q9UNL2,O75381,Q15006,O43615,Q96HY6,Q9H300,Q10713,Q3ZCQ8,O14737,Q8N766,Q15629,O15258,P51572,P49458,Q15154,Q9NQ11,Q8NFH5,Q8NBM4,Q8NFQ8,O96008,O95140,Q5JRA6 80 +Positive regulation of fatty acid transport 0.7654104586619968 2.713813155510592 0.0066513669398133 1.0 0.0399472427241616 2 P14174 1 +Cellular ion homeostasis 0.4474083897181117 2.713793856370418 0.0066517544180704 1.0 0.0399472427241616 96 Q05086,Q96A33,P51790,P05067,O75787,Q9NWR8,P16615,Q16891,O76024,O43819,Q9Y639,O95202,Q92544,P09601,Q96AQ8,Q9NWW5,P05023,P35670,P51572,Q8N511,Q9NQ11,O75027,Q8IYU8,Q9HD20,Q9UM00,O75880,Q93050,Q9Y3D6,Q8WWC4,P50897,P06576,P98194,Q8NEW0 33 +Response to phorbol 13 acetate 12 myristate 0.7651183172655596 2.7123242313192977 0.0066813204789635 1.0 0.0399816550919581 2 Q9NRA0 1 +Cellular response to insulin like growth factor stimulus 0.791268064120406 2.707021913715321 0.0067889775906595 1.0 0.0401799145166142 3 Q9BSK2 1 +Ion homeostasis 0.4279234960560205 2.706050314568434 0.0068088728871524 1.0 0.0402611614196842 115 Q05086,Q96A33,P51790,P05067,O75787,Q9NWR8,P16615,Q16891,O76024,O43819,Q9Y639,O95202,Q92544,P09601,P30519,Q96AQ8,Q9NWW5,P05023,P30536,Q9HD47,P35670,P51572,Q8N511,Q9NQ11,O75027,Q8IYU8,Q9HD20,Q8NE01,Q9UM00,O75880,Q93050,Q9Y3D6,Q8WWC4,P50897,P06576,P98194,Q8NEW0 37 +Mitochondrial cytochrome c oxidase assembly 0.8416739830260555 2.704103658110947 0.0068488920110192 1.0 0.0404038259507898 8 O75880,Q15070,O43819,Q8N8Q8,Q9GZY4,Q96I36,Q9Y2R0 7 +Protein transmembrane import into intracellular organelle 0.767559210132452 2.7010089100244135 0.0069129486526091 1.0 0.0405759065956869 14 O60830,Q15388,Q3ZCQ8,O14925,Q96DA6,O75381,Q99595,O43615 8 +Chondroitin sulfate proteoglycan metabolic process 0.817291826140985 2.6997864586409825 0.0069383994904821 1.0 0.040622306613334 4 Q96L58,Q9NX62 2 +Microglial cell activation 0.7619047619047672 2.695927477888833 0.0070192947160763 1.0 0.0409490222578633 2 P05067 1 +Neuroinflammatory response 0.7619047619047636 2.6959274778888123 0.0070192947160767 1.0 0.0409490222578633 2 P05556 1 +Response to corticosterone 0.7616126205083343 2.694435171926918 0.0070508041146761 1.0 0.0410594551834131 2 P07196 1 +Regulation of vasoconstriction 0.7616126205083338 2.694435171926918 0.0070508041146761 1.0 0.0410594551834131 2 P42892 1 +Regulation of amino acid transmembrane transport 0.7884278199883062 2.6929489818900643 0.0070823105500463 1.0 0.0411328498849668 3 Q15041,P05556 2 +Regulation of l glutamate import across plasma membrane 0.7884278199883062 2.6929489818900643 0.0070823105500463 1.0 0.0411328498849668 3 Q15041,P05556 2 +L glutamate import across plasma membrane 0.7884278199883062 2.6929489818900643 0.0070823105500463 1.0 0.0411328498849668 3 Q15041,P05556 2 +Response to interleukin 12 0.760151913526161 2.686969404737016 0.0072103556878666 1.0 0.0416910557399411 2 Q08722 1 +Chondroitin sulfate biosynthetic process 0.7869583917585656 2.685658381698126 0.0072387057999359 1.0 0.0417809650415398 3 Q96L58 1 +Chondroitin sulfate proteoglycan biosynthetic process 0.7869583917585656 2.685658381698126 0.0072387057999359 1.0 0.0417809650415398 3 Q96L58 1 +Energy derivation by oxidation of organic compounds 0.4027415680333748 2.658131716255725 0.0078575176943955 1.0 0.0444052757557524 135 O14949,P21912,P04062,O95168,P56385,O96000,Q9UDW1,O14548,O43819,Q9Y6M9,P13073,O43676,P22695,P00846,O95139,P14406,Q7KZN9,Q13423,Q9NZ45,P20674,P03886,P03915,P08574,O75964,O95167,P00403,P14927,P24539,Q9H3K2,P06576,Q15070,Q9Y375,Q9BSK2 33 +Metal ion homeostasis 0.4487026187401642 2.6525700804693764 0.0079881543436057 1.0 0.0445575069195276 85 Q96A33,P05067,Q9NWR8,P16615,Q16891,O76024,O43819,Q9Y639,O95202,P09601,P30519,Q96AQ8,P05023,P35670,P51572,Q8N511,Q9NQ11,O75027,Q8IYU8,Q9HD20,Q8NE01,Q9UM00,O75880,Q9Y3D6,Q8WWC4,P98194,Q8NEW0 27 +Perk mediated unfolded protein response 0.8071563478697756 2.650858086091152 0.0080287568527857 1.0 0.0445575069195276 4 P57088,Q15363 2 +Divalent inorganic cation homeostasis 0.4511527547266435 2.646621908317468 0.0081300195428672 1.0 0.0449388379134951 60 Q96A33,P05067,Q9NWR8,O76024,Q16891,P16615,Q9Y639,O95202,Q96AQ8,P35670,P51572,Q9NQ11,Q8IYU8,Q9HD20,Q8NE01,Q9UM00,Q9Y3D6,Q8WWC4,P98194,Q8NEW0 20 +Liposaccharide metabolic process 0.6588882525165046 2.644269383583439 0.0081867472687056 1.0 0.045175897016154 20 Q9Y2B2,P04062,Q99805,Q96S52,P17900,O60762,Q9H490,Q92643,Q8NBX0,O43292,Q9NZD2,Q9NWW5 12 +Ceramide metabolic process 0.6303200115747115 2.641208504492848 0.0082610861308318 1.0 0.0454708012327744 22 O95470,P04062,Q99805,P27544,Q96G23,P17900,Q53H12,Q13510,O15269,Q9NWW5 10 +Regulation of hormone levels 0.4512841076065227 2.640596322853207 0.0082760263223182 1.0 0.0455066682777109 65 Q8N183,Q9BRT2,O75787,Q53GQ0,P50416,P16435,P62820,O95470,Q9Y394,Q15907,Q9HB40,P42892,P05023,P30536,Q6NXT4,Q6NUM9,Q6UX07,Q8NBQ5,Q8TC12,O75844,Q8N5M9,Q8NBN7 22 +Membrane docking 0.560951476866684 2.639800417538925 0.008295486404791 1.0 0.0455066682777109 30 P56962,O95721,O15400,O43752,Q9P253,Q9UNK0,O60499,A0FGR8,Q12846,Q13190,P16615,Q96GC9,P61026,Q9UEU0 14 +Positive regulation of antigen receptor mediated signaling pathway 0.8241411173281268 2.6379586388079557 0.0083406754183037 1.0 0.0456777928948715 5 P00813 1 +Positive regulation of t cell receptor signaling pathway 0.8241411173281268 2.6379586388079557 0.0083406754183037 1.0 0.0456777928948715 5 P00813 1 +Negative regulation of blood circulation 0.7771920358390645 2.6370312526154973 0.0083635125809546 1.0 0.0457644678361041 3 P16615 1 +Embryonic heart tube morphogenesis 0.7769274053735084 2.6357094899033 0.0083961580550098 1.0 0.0457837522145441 3 Q15363 1 +Proton transporting two sector atpase complex assembly 0.8235285436285192 2.635043149147853 0.0084126588039319 1.0 0.0458030330876294 5 Q15070,Q8N511,Q9BUB7 3 +Eosinophil activation 0.7493426818580211 2.631502282063393 0.0085008296235769 1.0 0.0460144409475207 2 Q12846 1 +Eosinophil mediated immunity 0.7493426818580211 2.631502282063393 0.0085008296235769 1.0 0.0460144409475207 2 Q12846 1 +Positive regulation of blood circulation 0.8222069141175896 2.628749351132259 0.0085699501006559 1.0 0.0463117833253991 5 P00813,P16615,P09493 3 +Attachment of gpi anchor to protein 0.8214888224779493 2.625327614759471 0.0086565630507347 1.0 0.0463186419992811 5 Q9H490,Q96S52,O43292 3 +Response to light intensity 0.7467134092901103 2.617951254993737 0.0088459440467691 1.0 0.0469864302175026 2 Q8NBN7 1 +Positive regulation of fatty acid oxidation 0.7467134092901099 2.6179512549937285 0.0088459440467694 1.0 0.0469864302175026 2 P50416 1 +Positive regulation of fatty acid beta oxidation 0.7467134092901099 2.6179512549937285 0.0088459440467694 1.0 0.0469864302175026 2 P50416 1 +Regulation of protein exit from endoplasmic reticulum 0.8391342497806511 2.6152362723342284 0.0089165750951376 1.0 0.0472607357911272 6 Q9NR31,Q9GZP9,P51572,P60033,Q8NBM4 5 +Protein insertion into mitochondrial inner membrane 0.8217586973588358 2.6085655096376597 0.0090922606522096 1.0 0.0476841439450235 8 Q9P0J0,Q53H12,Q9Y5J9,Q9Y5J7,Q9Y584 5 +Sterol import 0.7446684195150516 2.607395517734725 0.0091233908987951 1.0 0.0476841439450235 2 Q6IAA8 1 +Positive regulation of triglyceride metabolic process 0.7446684195150522 2.607395517734725 0.0091233908987951 1.0 0.0476841439450235 2 Q8NCG7 1 +Retinal rod cell differentiation 0.7434998539293052 2.601357350825024 0.0092855673389922 1.0 0.0482228986387758 2 P54802 1 +Camera type eye photoreceptor cell differentiation 0.7434998539293052 2.601357350825024 0.0092855673389922 1.0 0.0482228986387758 2 P54802 1 +Retinal rod cell development 0.7434998539293052 2.601357350825024 0.0092855673389922 1.0 0.0482228986387758 2 P54802 1 +Regulation of torc2 signaling 0.7411627227578187 2.5892672099996408 0.0096180428661538 1.0 0.0495796937317915 2 Q9NWS0 1 +Alanine transport 0.7376570260005881 2.571097405240956 0.0101376809166124 1.0 0.0516313452284822 2 P08195 1 +Glutamine transport 0.7376570260005844 2.571097405240933 0.0101376809166131 1.0 0.0516313452284822 2 Q15758 1 +Cellular copper ion homeostasis 0.80954848149022 2.5682162611841415 0.0102223360036139 1.0 0.0519715026725795 5 O75880,O43819,P35670 3 +Sterol biosynthetic process 0.5568002695407607 2.567155019550963 0.010253676121223 1.0 0.0520902705987114 28 P16435,O75477,Q15125,Q9UKR5,Q16850,Q14534,O94905,O75845,P37268,Q14739,P00387,Q15800,Q15392,Q15738 14 +Negative regulation of gliogenesis 0.7883812906359366 2.5594216284381712 0.0104846493365156 1.0 0.0527863277673167 4 Q96G23 1 +Oligosaccharide lipid intermediate biosynthetic process 0.8257923026398788 2.55250973395697 0.010694992103494 1.0 0.0535529023575815 6 Q86YN1,Q96AA3,Q9BT22 3 +Lipid metabolic process 0.3676289120661965 2.5515326536756335 0.0107250273507264 1.0 0.0536497919889212 300 O00767,P04062,Q86YN1,P28288,Q9UKR5,Q96G23,P05067,Q9BQE5,Q9NZD2,P14174,Q6IAA8,Q96BW9,Q5T8D3,Q9HB40,P51648,P21964,O95864,Q16850,O94905,O14735,P17900,Q9NRA0,Q8NBX0,O75844,Q15738,Q9NUQ2,Q9H4L5,Q643R3,Q9H6K4,P50897,Q9BWD1,Q9Y2B2,P27544,Q99623,O14773,Q9BT22,Q8N9F7,O95470,O43808,Q9Y394,Q9H6V9,Q6Y1H2,P07602,Q9NPH0,Q9NX62,Q96AA3,Q9NZJ7,Q9UKU0,P60033,Q14534,Q5SGD2,O43292,Q15125,Q9H7Z7,Q96DA6,Q9UBV2,P06576,Q15392,Q8NBN7,Q15800,Q53GQ0,P50416,O15269,P23786,O43681,Q9NTJ5,Q86UL3,A1L0T0,Q13510,Q9NWW5,P30536,Q96N66,O75477,Q9UG56,Q6NUM9,O75845,Q53H12,Q6UX07,Q8TC12,Q9P035,Q8NF37,Q96S52,Q9BY49,Q68D91,Q92604,Q99735,P37268,Q10713,P16435,Q2TAA5,Q9H490,P00387,P05023,Q99805,Q8NBQ5,Q14739,Q6IAN0,Q8NHP8,O15118,Q92643,O00116,Q8NCG7 102 +Lipoprotein localization 0.8056926369967371 2.549686425560869 0.0107819848234826 1.0 0.0538110068254549 5 O15260,Q96GC9 2 +Phosphatidylserine acyl chain remodeling 0.7326906222611794 2.5452855509618995 0.0109188408155116 1.0 0.0539116728579458 2 Q643R3 1 +Lipoprotein metabolic process 0.6693633503233509 2.5429752338332423 0.0109913019409293 1.0 0.0539116728579458 18 Q9Y2B2,P04062,Q96S52,P50897,O60762,Q8N2K0,Q92643,Q9BQE5,Q9H490,O43292,Q9H2M9,Q9NUJ1 12 +Mitochondrial electron transport ubiquinol to cytochrome c 0.8041261847700637 2.5421463999367244 0.0110174015626032 1.0 0.0539116728579458 5 O14949,Q9UDW1,P08574 3 +Positive regulation of autophagy 0.5510314801871466 2.5415556727106283 0.0110360369020034 1.0 0.0539116728579458 29 Q86UE4,P27544,P09601,P21796,Q9BXS4,P12235,Q9Y371 7 +Membrane protein intracellular domain proteolysis 0.7312299152790057 2.5376778733002916 0.0111590644741974 1.0 0.0539116728579458 2 Q92542 1 +Sphingosine biosynthetic process 0.8030727311427898 2.5370716897764134 0.0111784060337316 1.0 0.0539116728579458 5 O15269,P04062,Q13510 3 +Pyramidal neuron differentiation 0.7567571925041167 2.5343129325106974 0.0112668065855638 1.0 0.054120466071053 3 O14949 1 +Suckling behavior 0.7559139370317485 2.5300456658955417 0.0114047682035833 1.0 0.0546422289992804 3 Q9GZP9 1 +Calcium ion export 0.7558379357661128 2.5296609521860947 0.0114172794661486 1.0 0.0546422289992804 3 O95202 1 +Complement activation 0.7553626050357495 2.5272544378720205 0.0114958184748719 1.0 0.0547745476631103 3 Q99623 1 +Regulation of humoral immune response 0.7553626050357495 2.5272544378720205 0.0114958184748719 1.0 0.0547745476631103 3 Q99623 1 +Regulation of complement activation 0.7553626050357495 2.5272544378720205 0.0114958184748719 1.0 0.0547745476631103 3 Q99623 1 +Melanocyte differentiation 0.7291849255039426 2.5270149096941297 0.0115036618943205 1.0 0.0547745476631103 2 Q86YV9 1 +Xenobiotic export 0.7280163599182138 2.520915380710343 0.0117049996303464 1.0 0.0549874244062566 2 P35670 1 +Xenobiotic transport across blood brain barrier 0.728016359918199 2.520915380710269 0.0117049996303488 1.0 0.0549874244062566 2 P33527 1 +Sphingolipid translocation 0.728016359918199 2.520915380710269 0.0117049996303488 1.0 0.0549874244062566 2 P33527 1 +Estrogen biosynthetic process 0.7540038280959862 2.520371201972892 0.0117231132689168 1.0 0.0549988696762798 3 Q53GQ0 1 +Lipid biosynthetic process 0.3968399541390058 2.5126270124974694 0.0119835959018483 1.0 0.0558777957480473 158 Q9Y2B2,O00767,P04062,Q86YN1,P28288,O14734,P27544,Q92604,Q9UKR5,Q96G23,O76062,Q53GQ0,P37268,P14174,O15269,Q10713,Q9NTJ5,O95470,Q96BW9,P16435,Q6Y1H2,Q9H490,Q86UL3,Q9NPH0,P00387,Q9NX62,Q13510,P05023,O95864,P30536,Q99805,Q96N66,Q9UKU0,O75477,Q16850,Q14534,Q9UG56,O94905,O14735,O75845,Q5SGD2,Q53H12,Q8NBQ5,Q9NRA0,Q8NBX0,O43292,Q9P035,Q14739,Q8NF37,Q6IAN0,Q15738,Q9NUQ2,Q9H4L5,Q643R3,Q15125,O95674,Q9H7Z7,Q96S52,Q9BY49,Q92643,O00116,Q15392,Q15800,Q8NCG7 64 +Intermediate filament bundle assembly 0.7521554245476232 2.510998130990072 0.0120390334374906 1.0 0.0559799575132621 3 P07196 1 +Porphyrin containing compound metabolic process 0.6511714642690656 2.5100155282032626 0.0120725852721361 1.0 0.0560116772561376 19 P30519,P09601,Q9P0S9,Q7KZN9,O00264,O75027,P22830 7 +Cellular response to lipoprotein particle stimulus 0.7974167619997136 2.509770934928071 0.0120809499964218 1.0 0.0560116772561376 5 P60033,O15118,Q5JRA6 3 +Regulation of electron transfer activity 0.7511403094263749 2.5058459169674077 0.0122158841216408 1.0 0.056556944358916 3 Q99623 1 +Positive regulation of amine transport 0.7501461133839925 2.5007966677338285 0.0123914299853145 1.0 0.0570460190015063 3 Q15041,P05556 2 +Positive regulation of amino acid transport 0.7501461133839925 2.5007966677338285 0.0123914299853145 1.0 0.0570460190015063 3 Q15041,P05556 2 +Regulation of spontaneous synaptic transmission 0.7501461133839905 2.5007966677338156 0.0123914299853149 1.0 0.0570460190015063 3 P05556,P05067 2 +Spontaneous synaptic transmission 0.7501461133839905 2.5007966677338156 0.0123914299853149 1.0 0.0570460190015063 3 P05556,P05067 2 +Regulation of histamine secretion by mast cell 0.749561659848043 2.497826904809142 0.0124957192342201 1.0 0.0573643144592065 3 O95219,Q9UNH7 2 +Positive regulation of mast cell activation involved in immune response 0.74956165984804 2.4978269048091293 0.0124957192342205 1.0 0.0573643144592065 3 O95219,Q9NRA0 2 +Lipid localization 0.4370753204663218 2.495176039113647 0.0125894655084803 1.0 0.0575921729778276 80 O15260,P04062,P28288,Q4KMQ2,P11166,Q9BQE5,P50416,Q9NZD2,Q9P260,Q9UJZ1,P14174,Q6IAA8,P23786,Q9UID3,O43808,Q9Y679,Q9H6V9,P07602,Q14108,Q96GC9,Q96AA3,P30536,Q9BUR5,Q9NZJ7,Q9BZF3,Q14534,P17900,Q9H4L5,Q9Y3D6,O95674,O15118,A0FGR8,O14975,Q9BSJ8 34 +Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.7224656733859257 2.4918788275021084 0.0127069379663049 1.0 0.057967079695345 2 Q92783 1 +Iron ion transmembrane transport 0.7742511129669365 2.4899112394045684 0.0127775001393768 1.0 0.0581033732472449 4 Q8N4V1,O75027 2 +Sulfate transport 0.7478082992402163 2.4889110191154566 0.0128135030765255 1.0 0.0581033732472449 3 Q02978,Q9UBX3 2 +Interleukin 17 production 0.7218813905930566 2.4888162048811044 0.0128169205692445 1.0 0.0581033732472449 2 P35232 1 +Urea cycle 0.721881390593053 2.4888162048810862 0.0128169205692452 1.0 0.0581033732472449 2 Q9Y619 1 +Interleukin 13 production 0.7218813905930535 2.4888162048810862 0.0128169205692452 1.0 0.0581033732472449 2 Q9NRA0 1 +Urea metabolic process 0.721881390593053 2.4888162048810862 0.0128169205692452 1.0 0.0581033732472449 2 Q9Y619 1 +Er nucleus signaling pathway 0.7282774550384138 2.4870314160806175 0.0128814023207233 1.0 0.0583146978846614 14 Q15363,O75477,Q96A33,P18031,O76024,P16615,P57088,Q9UKV5,Q9UM00 9 +Regulation of er to golgi vesicle mediated transport 0.7912502636700969 2.4799003824166346 0.0131419092959035 1.0 0.0592884477426802 5 Q9P2W9 1 +Regulation of triglyceride metabolic process 0.7448860315604979 2.4740291897513917 0.0133598780710766 1.0 0.0601056402811773 3 Q96N66,Q8NCG7 2 +Secretion 0.3938681544783831 2.4705224929495224 0.0134915834091617 1.0 0.0605313103058475 156 Q8N183,Q9BRT2,Q9Y5U9,P50416,O43760,P16615,Q9NV70,Q9BRK5,P14174,Q9Y3E7,Q9HCU5,O43633,Q99584,P52789,O95721,P62820,P27824,P00813,P09601,Q15907,Q12846,P55327,P49755,Q13505,Q86UL3,P11279,Q96KC8,Q92783,P56962,P35670,O00560,Q16850,Q9NQ11,Q9H4A6,Q9NRA0,P61026,P00403,Q96PC5,Q9P253,Q9H7Z7,P50897,Q9UBV2,Q8N5M9,P30511,Q5JRA6,Q9UEU0,Q9UNH7 47 +Eye photoreceptor cell development 0.7437171244886075 2.468068739488209 0.0135844230453054 1.0 0.0607044815095819 3 P54802,Q8NBN7 2 +Photoreceptor cell maintenance 0.743717124488597 2.468068739488151 0.0135844230453077 1.0 0.0607044815095819 3 P11166,P51790 2 +Cellular hormone metabolic process 0.6444179269625488 2.4671256806181754 0.0136202542641994 1.0 0.0607862048453403 19 O95470,Q9Y394,Q6NUM9,Q53GQ0,Q6UX07,Q8NBQ5,Q8TC12,P42892,Q8NBN7,P30536 10 +Protein insertion into er membrane 0.705937096720062 2.46298536366249 0.0137785540371997 1.0 0.0608873121968673 15 Q8N4V1,Q5J8M3,P49069,Q96A33,Q8N766,Q15006,Q9NPA0,Q15629,O43681 9 +Phosphate ion transmembrane transport 0.7427109235887761 2.4629344179181887 0.0137805119600975 1.0 0.0608873121968673 3 Q9UBX3 1 +Phosphate ion transport 0.7427109235887761 2.4629344179181887 0.0137805119600975 1.0 0.0608873121968673 3 Q9UBX3 1 +Lipoprotein catabolic process 0.7874824410901062 2.4615946366277166 0.0138320900716841 1.0 0.0608873121968673 5 Q9NUJ1 1 +Protein depalmitoylation 0.7874824410901062 2.4615946366277166 0.0138320900716841 1.0 0.0608873121968673 5 Q9NUJ1 1 +Torc2 signaling 0.7413793103448364 2.4561345858119736 0.0140440549733562 1.0 0.0616955523997777 3 Q9NWS0,Q96A49 2 +Vesicle fusion with golgi apparatus 0.8024264685336616 2.4414704055141914 0.0146275871936483 1.0 0.063829468224223 6 Q13190,Q9UEU0,Q9BSR8,O15155 4 +Negative regulation of glycoprotein metabolic process 0.7638818555330094 2.4385177113575076 0.0147476359844578 1.0 0.0641703212613265 4 Q9BXS4,Q9NQX7 2 +Ceramide biosynthetic process 0.7625103333339758 2.437697441565583 0.0147811397490853 1.0 0.0641703212613265 11 P04062,P27544,Q96G23,Q53H12,Q13510,O15269 6 +Vesicle docking 0.6644132658575476 2.4360473313794007 0.0148487414428089 1.0 0.0643629490487102 17 P56962,O15400,O43752,Q9UNK0,Q9P253,O60499,Q13190,P61026,Q9UEU0 9 +Hypoxia inducible factor 1alpha signaling pathway 0.7113643003213554 2.433488011264304 0.0149541306368836 1.0 0.0646922231925623 2 Q15118 1 +Regulation of acyl coa biosynthetic process 0.7113643003213554 2.433488011264304 0.0149541306368836 1.0 0.0646922231925623 2 Q15118 1 +Steroid metabolic process 0.4329007904218434 2.4329704311017615 0.0149755237894539 1.0 0.0647418670844739 73 P04062,P28288,O14734,Q9UKR5,P05067,Q53GQ0,P37268,Q9BQE5,Q6IAA8,P16435,O95470,P00387,Q13510,Q9NWW5,P05023,P30536,O75477,Q16850,Q14534,O94905,O75845,Q8NBQ5,Q14739,Q15738,Q9H4L5,Q15125,O15118,Q15392,Q15800 29 +Regulation of cardiac muscle cell action potential involved in regulation of contraction 0.736674924241258 2.4320658096256116 0.0150129792762776 1.0 0.0648608396529056 3 Q9HD47 1 +Inorganic anion transport 0.5417324106668623 2.431666550266287 0.0150295366798987 1.0 0.0648894282052769 27 Q9C0H2,Q4KMQ2,Q9UHG3,P51790,P45880,Q96S66,Q15043,P21796,Q9Y277,Q9UBX3,O43681,P30536 12 +Positive regulation of striated muscle contraction 0.7107800175284953 2.4304030235307033 0.0150820415533512 1.0 0.0649871731090936 2 P05023 1 +Glycolipid biosynthetic process 0.7690073801362002 2.428464008482555 0.0151629300180675 1.0 0.0652495762412294 10 Q9Y2B2,Q99805,Q96S52,Q92643,Q9H490,Q8NBX0,O43292 7 +Amino acid transmembrane transport 0.6997756586867456 2.427778364675999 0.0151916238089944 1.0 0.0653299869730669 15 O75746,P30825,Q9Y619,Q96QD8,Q96NB2,P05556,P08195,Q15758,Q9UJS0,O75915,Q9H936,Q15041,O60831 13 +Cristae formation 0.7768238003982841 2.427334839767608 0.015210210524815 1.0 0.065366856027645 9 Q5XKP0,Q9NX63,Q9BUR5,Q9Y512,O95202,Q16891,Q6UXV4 7 +Gland development 0.4323416121021792 2.425857701838557 0.0152722571439365 1.0 0.0654490242108332 72 Q05086,Q9NZJ7,Q99623,P00813,P09601,P07602,P50416,Q13505,Q86UL3,Q9NQC3,Q14118,O75844,P00403,P30536 14 +Relaxation of cardiac muscle 0.7099035933391877 2.4257733250439664 0.0152758080777479 1.0 0.0654490242108332 2 P05023 1 +Establishment or maintenance of transmembrane electrochemical gradient 0.7099035933391754 2.425773325043903 0.0152758080777506 1.0 0.0654490242108332 2 Q16611 1 +Steroid catabolic process 0.7341734289165762 2.419238289947066 0.0155530479548013 1.0 0.0664030719744561 3 Q8NBQ5 1 +L amino acid transport 0.733294255568579 2.4185236655072546 0.0155836318418753 1.0 0.066490162525335 13 O75746,P30825,Q9Y619,Q96QD8,P05556,P08195,Q15758,Q9UJS0,O75915,Q9H936,Q15041,O60831 12 +Response to muscle activity 0.7784150615018021 2.417371426000775 0.0156330558585238 1.0 0.0666048664909051 5 Q9UDX5 1 +Positive regulation of fatty acid metabolic process 0.7594655609655054 2.416529620224976 0.0156692513002698 1.0 0.0666206955754396 4 P50416 1 +Dendrite self avoidance 0.7332261868655119 2.4143755751632 0.0157622054849275 1.0 0.0666206955754396 3 P35613 1 +Very long chain fatty acid catabolic process 0.7584860886920601 2.411644891565551 0.0158807404773217 1.0 0.0666206955754396 4 Q15067,P28288 2 +Sphingoid metabolic process 0.7956506939556875 2.4089850787823353 0.0159969519902751 1.0 0.0668215618375802 6 O15269,P04062,Q13510 3 +Cd40 signaling pathway 0.7577738779511771 2.408091179566698 0.0160361754049649 1.0 0.0669336016902884 4 Q99623,P35232 2 +Hormone catabolic process 0.7318899851173635 2.4075111479203892 0.0160616718276942 1.0 0.0669971844672128 3 P42892 1 +L serine transport 0.731151373465811 2.4037142044586 0.0162294557573878 1.0 0.0675675300919821 3 Q15758,Q96QD8 2 +Positive regulation of necrotic cell death 0.7567440227282647 2.4029497721182462 0.0162634210759016 1.0 0.0676456828470176 4 P00403 1 +Positive regulation of phosphatidylinositol 3 kinase signaling 0.7754433405784578 2.402825412788661 0.01626895252295 1.0 0.0676456828470176 5 O00165 1 +Mitochondrion endoplasmic reticulum membrane tethering 0.7306438063689025 2.401103948811945 0.0163456924726532 1.0 0.0678782954589571 3 P16615 1 +Regulation of mitophagy 0.7937404315762963 2.399803287916808 0.0164038844786453 1.0 0.0680766420067368 6 P27544,P12235,P21796 3 +Nuclear envelope organization 0.522499045273488 2.395937527134132 0.0165779155997067 1.0 0.0686679143622372 33 O14657,Q9H6H4,Q9BTV4,O94901,Q86XL3,P02545,Q6NUK4,Q9Y2U8,P50402,O75844,Q9Y3E7,Q9UH99,O43633 13 +Manganese ion transport 0.7545360260732749 2.3919157020150985 0.0167606914620253 1.0 0.0690307847723035 4 Q9HD20,P98194 2 +Manganese ion transmembrane transport 0.7545360260732749 2.3919157020150985 0.0167606914620253 1.0 0.0690307847723035 4 Q9HD20,P98194 2 +Peripheral nervous system axon regeneration 0.7541274109211757 2.389872080641844 0.0168542419589263 1.0 0.0693723149482165 4 Q96G23,P30536 2 +Mitochondrial atp synthesis coupled proton transport 0.7523978698094049 2.385341933679426 0.0170632533423282 1.0 0.0699679132027129 11 O75964,P00846,P06576,P24539 4 +Pointed end actin filament capping 0.7011393514461008 2.3793296799690755 0.0173441561394274 1.0 0.0707367566993241 2 Q9NYL9 1 +Export from cell 0.3856513333284896 2.37594534317896 0.0175040554070871 1.0 0.0712670865501757 143 Q8N183,Q4KMQ2,Q9BRT2,Q15758,Q9Y5U9,P50416,O43760,P16615,Q9NV70,Q9BRK5,Q9Y3E7,P14174,Q9HCU5,O43633,Q99584,O95721,P62820,O95219,P27824,Q9Y3C0,P09601,Q15907,Q12846,Q8IYI6,P49755,P20020,P11279,Q96KC8,Q92783,P05023,O60645,P56962,P35670,O00560,Q16850,Q9NQ11,Q9H4A6,Q9NRA0,P55011,P61026,Q96TA1,P51809,P30040,Q96PC5,P54709,P20339,Q9P253,P50897,Q9UBV2,Q8N5M9,Q5EBL8,P30511,Q5JRA6,Q9UEU0,Q9UNH7 55 +Lytic vacuole organization 0.5299238429492211 2.374332761294478 0.01758069840272 1.0 0.0713280293181829 29 P54802,P04062,O75503,Q9P253,Q96ED9,Q8N511,P50897,O75787,O14773,Q14108,Q9BZG1,Q9Y3E7,Q6IAA8,Q9NWW5,P11117 15 +Respiratory chain complex iii assembly 0.7880528451897262 2.3724045621847423 0.0176727281353239 1.0 0.0714792870306039 6 Q9BRT2,Q6DKK2,Q9BSK2,Q69YU5 4 +Glycoprotein catabolic process 0.6996786444639203 2.371563083818523 0.0177130226545465 1.0 0.0715979020983776 2 Q8TCJ2 1 +Regulation of amino acid transport 0.7503653902367877 2.3710328579314925 0.0177384540584848 1.0 0.0716120149003024 4 P05556,Q15041,O75915 3 +Amine transport 0.7503653902367877 2.3710328579314925 0.0177384540584848 1.0 0.0716120149003024 4 P05556,Q15041,O75915 3 +Cellular homeostasis 0.3875426628342338 2.3686323326998826 0.0178539920410976 1.0 0.0719449753359785 158 Q8N183,Q05086,Q4KMQ2,Q96A33,P51790,P05067,O75787,Q9NWR8,Q9NQC3,P16615,Q16891,O76024,O43819,Q9Y639,P52789,Q96ER9,O95202,Q92544,P09601,Q15907,Q96AQ8,Q9NWW5,P05023,P35670,P51572,Q8N511,Q9NQ11,Q9BWH2,O75027,Q8IYU8,Q9HD20,P13473,Q9UM00,O75880,Q93050,Q9Y3D6,Q8WWC4,P50897,Q8N5M9,P06576,Q07820,P98194,Q8NEW0 43 +Regulation of mast cell activation involved in immune response 0.7497807658579553 2.3681013046519332 0.0178796394576785 1.0 0.072003878087431 4 O95219,Q9NRA0,P09601 3 +Copper ion homeostasis 0.7868711706582209 2.366700621520698 0.0179474441032416 1.0 0.0721878712914119 6 O75880,O43819,P35670 3 +Bone growth 0.7236183909651024 2.364888048384373 0.018035521910392 1.0 0.0724528535575626 3 O75844 1 +Growth plate cartilage development 0.7236183909651024 2.364888048384373 0.018035521910392 1.0 0.0724528535575626 3 O75844 1 +Regulation of endoplasmic reticulum tubular network organization 0.7487756045993486 2.3630585431415527 0.0181248061751542 1.0 0.072677355473837 4 Q15041 1 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.7787810601629525 2.361980230671638 0.0181776115252318 1.0 0.072799661372217 7 Q8N766,Q15006,Q9NPA0,Q8N4V1 4 +Branching involved in salivary gland morphogenesis 0.7224196346326622 2.35869234987038 0.0183394527090534 1.0 0.0733128887230257 3 Q14118 1 +Protein localization to vacuole 0.5741697774655007 2.3467824485228803 0.0189363077052833 1.0 0.0753086906739631 23 Q9NUN5,P60033,Q96RL7,Q9NQ11,Q9NQC3,Q14108,P13473,Q9Y371 8 +Cop9 signalosome assembly 0.6950043821209546 2.3466599225493696 0.0189425352461163 1.0 0.0753086906739631 2 Q99627 1 +Zinc ion transport 0.7637426900584849 2.3453002385096293 0.0190117632425239 1.0 0.0754574128779956 5 Q8NEW0,Q15043,Q6NXT4,Q8N1S5 4 +Regulation of b cell apoptotic process 0.719797694932868 2.345124591756377 0.0190207223706191 1.0 0.0754574128779956 3 P00813 1 +Negative regulation of b cell apoptotic process 0.719797694932868 2.345124591756377 0.0190207223706191 1.0 0.0754574128779956 3 P00813 1 +Positive regulation of ire1 mediated unfolded protein response 0.7188778492109968 2.340359317810705 0.0192651949777671 1.0 0.0760026721846021 3 P57088,P18031 2 +Positive regulation of endoplasmic reticulum unfolded protein response 0.7188778492109968 2.340359317810705 0.0192651949777671 1.0 0.0760026721846021 3 P57088,P18031 2 +Angiogenesis involved in wound healing 0.744246157153942 2.3402962849200915 0.0192684470688597 1.0 0.0760026721846021 4 P55011,Q14118 2 +Ceramide transport 0.7741989052481264 2.339492554306602 0.0193099564716787 1.0 0.0760486107993089 7 Q9NZD2,P07602 2 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.71800116890707 2.3358150764831636 0.0195008815144785 1.0 0.0765494615312785 3 P04439,Q03518 2 +L alpha amino acid transmembrane transport 0.742823667252478 2.335468753521645 0.0195189463786655 1.0 0.0765743281009188 11 O75746,P30825,Q9Y619,P05556,P08195,Q15758,Q9UJS0,O75915,Q15041,O60831 10 +Positive regulation of erad pathway 0.7432366183036311 2.335214330355837 0.0195322268878896 1.0 0.0765804066811675 4 Q4ZIN3,P51572 2 +Calcium ion import 0.7003917097644954 2.331722608745909 0.0197152886415874 1.0 0.0771895320695632 14 Q8WWC4,Q9NWR8,P16615,Q8IYU8,P21796,O75844,Q96AQ8 7 +Regulation of steroid biosynthetic process 0.750067382646947 2.33157499418907 0.0197230605839509 1.0 0.0771895320695632 10 P16435,O75477,Q13510,P05023,P30536 5 +Dicarboxylic acid transport 0.6823083019499662 2.327161661795225 0.0199566626659335 1.0 0.0778238314714541 15 O75746,P05556,Q9BQT8,Q15758,Q9UJS0,Q9H2D1,O75915,Q02978,P55011,Q15041,Q9UBX3,O60831 12 +L aspartate transmembrane transport 0.7413037123648094 2.3254754216645988 0.0200465526700062 1.0 0.0780345234524749 4 O75746,Q15758,Q9UJS0 3 +Positive regulation of macroautophagy 0.634456208385008 2.3251754489307435 0.0200625805716661 1.0 0.0780503730463863 18 P27544,P09601,P21796,O15269,P12235,Q9Y371 6 +Lysosomal membrane organization 0.6894536955886719 2.3169881325720176 0.0205043782393796 1.0 0.0791090905122166 2 Q9Y3E7 1 +Transition metal ion transport 0.608108419598423 2.3133199276346876 0.0207050558521255 1.0 0.0795456833833867 20 Q6NXT4,P35670,Q8N4V1,O15173,Q15907,Q15043,O75027,P98194,Q9HD20,Q8NEW0 10 +Amyloid precursor protein metabolic process 0.6080811286705936 2.3131385698832236 0.0207150217144236 1.0 0.0795456833833867 20 O75298,O95197,Q9NQX7,P49755,Q9NQC3,Q15392 6 +Prostate gland development 0.7756402864738527 2.312291423682003 0.0207616289938419 1.0 0.0796777860504409 6 Q9NZJ7,P07602 2 +Gpi anchor metabolic process 0.7683687735491991 2.310791802401146 0.020844357531395 1.0 0.0798076046715229 7 Q9Y2B2,Q96S52,Q92643,Q9H490,O43292 5 +Proteoglycan metabolic process 0.7376470838062197 2.308379389218436 0.0209780443289282 1.0 0.0801783801986203 11 Q99805,Q96L58,Q7LGA3,Q8NCH0,Q8WVQ1,Q9P2E5,Q9NX62 7 +Positive regulation of peptidase activity 0.4778083710178895 2.3057825742553537 0.0211227843959711 1.0 0.0806843396939143 44 Q96HY6,Q6IC98,Q9NZJ7,Q9Y3D6,Q9NR28,P51572,Q96A26,P61289,Q9P0J0,Q9BXK5,O14737,Q9UL46,Q92542 13 +Regulation of alcohol biosynthetic process 0.7556071459282253 2.305064049578235 0.0211629865455726 1.0 0.0807434109698997 5 P16435,O75477 2 +Regulation of cholesterol biosynthetic process 0.7556071459282253 2.305064049578235 0.0211629865455726 1.0 0.0807434109698997 5 P16435,O75477 2 +Protein localization to microtubule end 0.6871165644171797 2.304462425716001 0.0211966992367089 1.0 0.0808247970895071 2 Q15555 1 +Amino acid import across plasma membrane 0.7739105001462449 2.303879418059379 0.0212294133704544 1.0 0.0809022828268107 6 P30825,P05556,P08195,O75915,Q15041 5 +Transition metal ion homeostasis 0.5250839732332996 2.3006273605136207 0.0214127031461344 1.0 0.0813632864598169 27 O75880,P30519,P35670,Q8N511,P09601,P05067,Q9NQ11,Q15043,O75027,Q8NEW0,O43819 11 +Sodium ion export across plasma membrane 0.7101110461718252 2.2948031254077037 0.0217444094613308 1.0 0.0824317682715259 3 P54709,P05023 2 +Eye photoreceptor cell differentiation 0.7349910069994623 2.2935884803986233 0.0218141477050659 1.0 0.082648146383442 4 P54802,Q8NBN7 2 +Positive regulation of autophagy of mitochondrion 0.752597590978764 2.290129845639025 0.0220137907042468 1.0 0.0829254798682871 5 P27544,P12235,P21796 3 +Negative regulation of fatty acid transport 0.7090839590022604 2.289449355757871 0.022053257254091 1.0 0.0830240273095191 3 Q9Y3D6 1 +Keratan sulfate metabolic process 0.7085395397885392 2.2866101178996403 0.0222185901457963 1.0 0.0835019899088994 3 O43505 1 +Atp biosynthetic process 0.5912929369340494 2.2847607101310534 0.0223268626336388 1.0 0.0835291573743893 21 O75746,P24539,Q9UJS0,P00846,P56385,Q9NRA0,P06576,O75947,Q9UJZ1,O75964,P00403 11 +Antiviral innate immune response 0.751512392839405 2.2847382024644936 0.0223281831523145 1.0 0.0835291573743893 5 Q99623,P35232,Q9NVI7 3 +Autophagosome organization 0.5206691008771566 2.282293639457274 0.0224720098192736 1.0 0.0840190607675936 28 P56962,P04062,P62820,O95219,Q9H0U4,P20339,Q5VWJ9,O95140,O75396,Q9NQ11,P16615,Q96GC9,Q9H2M9,Q9Y371 14 +Positive regulation of organic acid transport 0.7505847953216368 2.280126797415077 0.0226001693146582 1.0 0.0841786649630995 5 P14174,P33121,Q15041,P05556 4 +Serine transport 0.7313650979245843 2.275217342425876 0.0228928950279558 1.0 0.0850568120332931 4 Q15758,Q96NB2,Q96QD8 3 +Endoplasmic reticulum calcium ion homeostasis 0.7383543429700636 2.2710898187198088 0.0231415412084954 1.0 0.085834080118783 10 Q9Y3D6,P51572,Q96A33,P16615,O76024,Q9UM00 6 +Trans synaptic signaling by trans synaptic complex 0.7051057589269027 2.2686798207965366 0.0232878036085963 1.0 0.0861318877942873 3 Q14118 1 +Purine nucleotide transport 0.7212215859682067 2.2642254096079943 0.0235602545323128 1.0 0.0869497844632276 12 O43808,Q08722,P12236,Q8TB61,O00400,Q6NUK1,P12235 7 +Sensory perception 0.4797340080537056 2.259971688357254 0.0238230080232666 1.0 0.0875147624703228 42 Q9H6K4,O60313,Q96DA6,P50897,O60443,Q9Y5J9,Q14108,Q9Y5J7,O43924,Q96HR9,Q9Y6M9,Q9NWW5 12 +Regulation of amyloid fibril formation 0.7647569761490887 2.259223455751395 0.0238694884851315 1.0 0.0875885445929955 6 Q99471,P05067 2 +Nucleotide transmembrane transport 0.7352442139905188 2.254956271698236 0.0241360736721703 1.0 0.0883185476075828 10 O43808,P12236,Q9H2D1,Q8TB61,P12235,Q9BSK2 6 +Ventricular cardiac muscle cell development 0.6774758983347992 2.2525908689018603 0.0242849573845393 1.0 0.0886079605490622 2 P02545 1 +Ventricular cardiac muscle cell differentiation 0.6774758983347992 2.2525908689018603 0.0242849573845393 1.0 0.0886079605490622 2 P02545 1 +Positive regulation of cardiac muscle cell proliferation 0.677475898334799 2.2525908689018603 0.0242849573845393 1.0 0.0886079605490622 2 Q16539 1 +Regulation of cardiac muscle cell proliferation 0.677475898334799 2.2525908689018603 0.0242849573845393 1.0 0.0886079605490622 2 Q16539 1 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.7254431468042624 2.245125229630213 0.0247600943681953 1.0 0.0898964939018795 4 O75787,P09493 2 +Bicarbonate transport 0.6760151913526213 2.2447029802766423 0.0247872066013195 1.0 0.0899449053326368 2 Q9Y6M7 1 +Neutrophil differentiation 0.7250979785089143 2.243367911134334 0.0248730993807639 1.0 0.0901595575591709 4 Q8N5M9,Q14739 2 +Calcium import into the mitochondrion 0.7476518218165553 2.242901198535917 0.0249031864659372 1.0 0.0902153170086783 8 Q8WWC4,Q9BPX6,Q9NWR8,Q8IYU8,P21796,Q96AQ8 6 +Ornithine metabolic process 0.6739702015775664 2.233647288914569 0.0255062898085685 1.0 0.0916373472043672 2 P78540 1 +Early endosome to golgi transport 0.7448678316742251 2.2288454175605894 0.0258241918570094 1.0 0.0924850409394742 8 O15260,P49257,O60499,Q13190,O60749,P20340 6 +Sensory perception of light stimulus 0.5935509380889713 2.2160388755934624 0.0266888398066773 1.0 0.0947388506024957 20 Q9H6K4,O60313,Q96DA6,P50897,O43924,Q96HR9,Q9NWW5 7 +Glycoside catabolic process 0.7374667350775315 2.2146379146361745 0.0267849274323614 1.0 0.0949766465390851 5 Q9NUJ1 1 +Nad biosynthesis via nicotinamide riboside salvage pathway 0.6698802220274646 2.2114916069840227 0.0270018124428725 1.0 0.0953314394954419 2 P43490 1 +Er overload response 0.7363223303450143 2.208900383543898 0.0271815705287072 1.0 0.0958106330515125 5 Q96A33,Q9UM00 2 +Negative regulation of organic acid transport 0.7182777839910268 2.20856892710955 0.0272046386274791 1.0 0.0958303281285565 4 Q9Y3D6,O75915 2 +Atp synthesis coupled proton transport 0.7102007523919898 2.205009453021382 0.0274534312008241 1.0 0.0965083461922346 12 O75964,P00846,P06576,P24539 4 +Regulation of glial cell proliferation 0.7346366905325102 2.20044221515266 0.0277755354799444 1.0 0.097221820704063 5 Q96G23 1 +Negative regulation of amyloid fibril formation 0.7340690984110319 2.1975922518651982 0.0279781758719959 1.0 0.0977738394498872 5 Q99471 1 +Proteoglycan biosynthetic process 0.723065739534661 2.191485251014933 0.0284166958996985 1.0 0.0989355684443904 10 Q99805,Q96L58,Q7LGA3,Q8NCH0,Q8WVQ1,Q9P2E5 6 +Glutamate receptor signaling pathway 0.7144049863221066 2.188744069938038 0.0286154469184809 1.0 0.0994683905664769 4 Q92542,Q8NCG7 2 +Protein n linked glycosylation 0.5645325059526007 2.186070230064058 0.0288104676031479 1.0 0.1000692097743035 22 Q9Y673,Q86YN1,Q9BYC5,P46977,Q9BT22,Q96AA3,Q9H0U3 7 +Neutral amino acid transport 0.7315789473684191 2.18507745548045 0.0288831679331815 1.0 0.1001856111943726 5 P08195,Q15758,Q96QD8,Q96NB2 4 +Erad pathway 0.4714761606056365 2.183739994500551 0.028981359122939 1.0 0.1002991920714026 42 Q6NTF9,P46379,P27824,Q9GZP9,O75477,P51572,Q9UBU6,Q9BUN8,Q96A33,Q9Y679,O94905,Q9UBV2,Q96CS3,Q4ZIN3,O76024,Q9UKV5,Q8NBM4 17 +Peroxisomal transport 0.7311388647550273 2.182863796309936 0.0290458418567396 1.0 0.1003249755707672 5 O75381,P40855,P28288 3 +Pigment metabolic process 0.5060749990515462 2.18148271213162 0.0291477317749002 1.0 0.1005493636459323 29 P30519,P00813,P09601,Q9P0S9,Q7KZN9,O00264,O75027,P22830 8 +Maintenance of protein location in mitochondrion 0.7129733154687159 2.1814035051200946 0.0291535846116284 1.0 0.1005493636459323 4 P30536 1 +Protein targeting to peroxisome 0.7129630737962528 2.1813509702577205 0.0291574671234298 1.0 0.1005493636459323 4 O75381,P40855 2 +Tetrapyrrole catabolic process 0.7307877027724494 2.181097001203927 0.0291762426086943 1.0 0.1005609882521418 5 P09601 1 +L glutamate transmembrane transport 0.7419543592744162 2.179511191580481 0.0292937141877138 1.0 0.1008062025394813 7 O75746,P05556,Q9UJS0,O75915,Q15041,O60831 6 +Phosphatidylcholine acyl chain remodeling 0.71253296132755 2.1791444044128965 0.0293209424529763 1.0 0.1008467399014907 4 Q8NF37,Q96N66 2 +Cardiolipin acyl chain remodeling 0.6634531113058812 2.176556074370944 0.0295137055647471 1.0 0.101193114909178 2 Q6UWP7 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.7114480239276606 2.1735758876123827 0.0297370008992865 1.0 0.1014757667906652 4 P30511,P10321 2 +Exocytosis 0.4103054934690189 2.1713841795438253 0.0299021437898403 1.0 0.1018795379227963 78 O43760,P16615,Q9NV70,Q9BRK5,Q9Y3E7,Q99584,O43633,O95721,O95219,Q9Y3C0,P09601,Q15907,Q12846,P49755,P11279,Q92783,O60645,P56962,O00560,Q9NQ11,Q9NRA0,P61026,P20339,Q9P253,Q8N5M9,P30511,Q5JRA6,Q9UEU0,Q9UNH7 29 +Regulation of dna helicase activity 0.6864406779660993 2.1705330087776633 0.0299664908291876 1.0 0.1020455149363261 3 Q04837,P33993 2 +Cellular potassium ion homeostasis 0.7103186202864777 2.167775243663962 0.0301757913042299 1.0 0.102651154577391 4 P55011,P54709,P05023 3 +Mitochondrial calcium ion homeostasis 0.6869685721766322 2.1643277625231 0.0304392034916369 1.0 0.1032781291026019 13 Q9Y3D6,Q8WWC4,P51572,O95202,Q8IYU8,Q16891,Q96AQ8 7 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.6844183973913862 2.1598298449290008 0.0307858443244426 1.0 0.1042375475881543 3 O75844 1 +Leukotriene biosynthetic process 0.7085266099465489 2.1585632685448344 0.0308840650046249 1.0 0.1044617494042443 4 Q9UJ14 1 +Positive regulation of endothelial cell development 0.659363131755774 2.1542482830155225 0.0312207062448048 1.0 0.1052718008113518 2 P35611 1 +Negative regulation of regulated secretory pathway 0.7076488846899359 2.154047594202075 0.0312364396708928 1.0 0.1052718008113518 4 P09601 1 +Negative regulation of leukocyte migration 0.7367346468877188 2.153326395424232 0.0312930357487559 1.0 0.105331386139881 7 Q5JRA6,P00813,P09601 3 +Protein localization to extracellular region 0.4064442493499295 2.1441769332251535 0.0320187125852584 1.0 0.1069693734680487 61 Q8N183,Q96PC5,P27824,Q9Y5U9,Q16850,Q15907,Q9UBV2,P50416,P49755,Q9NQ11,Q9H4A6,Q8N5M9,Q5JRA6,P61026,Q96KC8 15 +Regulated exocytosis 0.4820365333992586 2.143646282489464 0.0320612393763095 1.0 0.1070566601782858 37 O95721,Q9P253,P09601,Q15907,Q12846,P49755,P30511,O43760,P16615,P11279,Q9NRA0,Q9BRK5,P61026,Q9UNH7,Q99584 15 +Response to progesterone 0.7221567100813522 2.137556063502988 0.0325527909232694 1.0 0.1084207240546444 5 Q05086 1 +Fatty acid alpha oxidation 0.7024546722939704 2.1272754697755274 0.0333972016846433 1.0 0.1103224494300876 4 O43808 1 +Regulation of calcium ion import 0.7008028956754353 2.118744199472725 0.0341120908058152 1.0 0.1115287097994985 4 P21796 1 +Endoplasmic reticulum unfolded protein response 0.5426652660515415 2.118054135380574 0.0341704832020985 1.0 0.1115882512972984 23 Q96HY6,Q15363,Q6NTF9,Q9BUN8,Q9GZP9,Q9Y4P3,O76024,P57088,Q9UKV5 9 +Phosphatidylglycerol metabolic process 0.6625867335807909 2.1165416116447924 0.0342987700453523 1.0 0.1119197130188233 14 Q96BW9,Q643R3,Q92604,O95674,Q99623,Q96DA6,Q6UWP7,Q8NF37 8 +Negative regulation of amyloid precursor protein catabolic process 0.7153068213264419 2.113394692353335 0.0345669998757245 1.0 0.1126577010428006 9 Q9NQC3,O75298,O95197 3 +Positive regulation of response to endoplasmic reticulum stress 0.7270447069949458 2.104503874674855 0.0353345169792536 1.0 0.1144733135685198 7 P57088,Q4ZIN3,P18031,P51572 4 +Long chain fatty acid import across plasma membrane 0.6979278532710697 2.103874568533185 0.0353893899238049 1.0 0.1145092068086317 4 P11166,P33121 2 +Positive regulation of cysteine type endopeptidase activity 0.4920233206150444 2.101060026732823 0.0356356972781763 1.0 0.1147655805781625 31 Q6IC98,Q9NZJ7,Q9Y3D6,Q9NR28,Q96A26,Q9P0J0,Q9BXK5,O14737 8 +Protein demannosylation 0.6718199311376479 2.0928450655051316 0.0363629874401858 1.0 0.116380879434 3 O60476 1 +Tail anchored membrane protein insertion into er membrane 0.6894824694600449 2.0925778811097877 0.0363868527764696 1.0 0.116380879434 12 Q8N4V1,Q5J8M3,P49069,Q8N766,Q15006,Q9NPA0,O43681 7 +Phosphatidic acid metabolic process 0.7107560437558113 2.089705424947194 0.0366442693931505 1.0 0.1170894716585839 9 Q9NUQ2,Q643R3,Q86UL3,Q9NPH0,Q8NF37 5 +Regulation of long chain fatty acid import across plasma membrane 0.6708974425652103 2.0879195768501453 0.0368050899143637 1.0 0.1173662219259856 3 P33121 1 +Cerebellar purkinje cell layer morphogenesis 0.670864896517301 2.0877457505479726 0.0368207755061915 1.0 0.1173662219259856 3 Q96D53 1 +Regulation of autophagy of mitochondrion 0.6250180689657393 2.086860184568825 0.0369007748860532 1.0 0.1175064675395881 16 P27544,O00165,P05141,Q9H300,P21796,P12235,P30536 7 +Macromolecule depalmitoylation 0.7231498054233225 2.0848016024906633 0.0370873132073339 1.0 0.1178704871555384 7 P50897,Q9NUJ1 2 +Mitochondrial electron transport nadh to ubiquinone 0.4921092135500696 2.083700372623126 0.0371874303194963 1.0 0.1181311655112759 30 O95169,O43676,O95168,O95139,P03915,O96000,O95167,P03886,P09622,O43674,Q9Y6M9,Q9Y375,P56556 13 +Protein localization to lysosome 0.6070966484156417 2.07942798967206 0.0375780301094974 1.0 0.1189667218985447 17 Q9NUN5,P60033,Q9NQC3,Q14108,P13473 5 +Potassium ion homeostasis 0.7105263157894735 2.0785313836101307 0.0376604434301799 1.0 0.1191276525488245 5 P55011,P54709,P05023,Q9BXP2 4 +Signal peptide processing 0.7277229194151555 2.0761005120386264 0.0378846558339085 1.0 0.1196473310516473 6 Q9H300,P67812,Q15005 3 +Cellular response to zinc ion 0.6682764163464809 2.073909590599352 0.0380877081803108 1.0 0.1199823822637004 3 P30536 1 +L methionine salvage from methylthioadenosine 0.6917467201700229 2.0718186207563174 0.0382823594748606 1.0 0.1203792112966717 4 Q13126,Q9BV57 2 +Amino acid salvage 0.6917467201700229 2.0718186207563174 0.0382823594748606 1.0 0.1203792112966717 4 Q13126,Q9BV57 2 +Regulation of natural killer cell activation 0.6676677191630855 2.0706527031521964 0.0383912631687113 1.0 0.1205474583767905 3 P11279 1 +Positive regulation of natural killer cell activation 0.6676677191630855 2.0706527031521964 0.0383912631687113 1.0 0.1205474583767905 3 P11279 1 +Long chain fatty acyl coa biosynthetic process 0.7137516913994044 2.0701540147160076 0.038437924004159 1.0 0.1206020296653778 8 Q6Y1H2,Q9UKU0 2 +Mammary gland epithelium development 0.7199438354063032 2.068550773245733 0.03858826140565 1.0 0.120933351155105 7 Q9NQC3 1 +Mitochondrial calcium ion transmembrane transport 0.6922210829802978 2.066903607538884 0.0387432377498395 1.0 0.1212444180397663 11 Q8WWC4,O95202,Q9NWR8,Q8IYU8,P21796,Q9BPX6,Q9UJZ1,Q96AQ8 8 +Plus end directed organelle transport along microtubule 0.6432953549518021 2.0660373304126383 0.0388249548688248 1.0 0.121383766946211 2 Q9Y496 1 +Estrogen metabolic process 0.7250410415354148 2.062686522601908 0.0391424212176292 1.0 0.1222007296550376 6 Q53GQ0,O95470 2 +Amyloid precursor protein catabolic process 0.6210354721449494 2.0623565971863833 0.0391737982974684 1.0 0.1222402271921004 16 O75298,O95197,P49755,Q9NQC3,Q15392 5 +Nadh oxidation 0.6424189307624945 2.061199556529452 0.0392840058331365 1.0 0.1225255566549045 2 Q16822 1 +Negative regulation of chemokine production 0.6409582237803151 2.053130568563989 0.0400599159728798 1.0 0.1241743264344537 2 P78540 1 +Retrograde trans synaptic signaling 0.6635278586862248 2.048469423943907 0.0405140251106366 1.0 0.1251986937558437 3 Q14118 1 +Neuron recognition 0.7095228014161434 2.0483610153944003 0.0405246384660076 1.0 0.1251986937558437 8 Q9Y639,P35613,Q9NQC3 3 +Negative regulation of anoikis 0.6871151458608933 2.0477207742134547 0.0405873670920478 1.0 0.1252158512316628 4 P05556,Q07820 2 +Endoplasmic reticulum localization 0.6633876283478366 2.04771701049307 0.0405877360916357 1.0 0.1252158512316628 3 A0FGR8 1 +Endoplasmic reticulum plasma membrane tethering 0.6633876283478366 2.04771701049307 0.0405877360916357 1.0 0.1252158512316628 3 A0FGR8 1 +Metal ion export 0.7090188756720223 2.0457605059137554 0.0407799394877477 1.0 0.1257493835503151 8 P54709,Q4KMQ2,P35670,O95202,P20020,P05023 6 +Modulation by host of symbiont catalytic activity 0.639497516798135 2.045054044059525 0.0408495302937779 1.0 0.125904501302069 2 Q9H1E3 1 +Amino acid import 0.7011857720705335 2.039677342688668 0.0413824730352607 1.0 0.1272070009970693 9 P30825,Q96NB2,P05556,P08195,Q15758,O75915,Q15041 7 +Tetrapyrrole biosynthetic process 0.6483641396484868 2.034197618026837 0.0419316746271096 1.0 0.12787404708549 14 Q9P0S9,Q7KZN9,O00264,O75027,P22830 5 +Regulation of protein catabolic process in the vacuole 0.7013101635927004 2.0314718419828366 0.0422071531174803 1.0 0.12787404708549 5 P60033,Q9NQ11 2 +Response to endoplasmic reticulum stress 0.3966048147840382 2.024361103741832 0.042933010783194 1.0 0.128444864524606 87 Q96HY6,P46379,Q9GZP9,Q96A33,P16615,O76024,P57088,O95881,Q15363,P27824,Q9UBU6,Q9Y679,Q9Y4P3,Q4ZIN3,Q9H3N1,P18031,Q6ZXV5,Q6NTF9,O75477,P51572,O60313,O94905,Q9UM00,Q8NBM4,Q9BUN8,Q9UBV2,Q96CS3,Q9UKV5 28 +Vesicle organization 0.3902069576086986 2.0230642172405315 0.0430665271502528 1.0 0.1287852905345169 101 O15400,Q8N6H7,P51790,Q9Y3E7,Q6IAA8,Q9HCU5,O43633,Q15363,P62820,O95721,Q9NR31,O95249,Q96ED9,Q12846,P49755,Q14108,Q9BZG1,Q92783,P56962,O00560,O60499,O15155,O75396,Q13190,Q9NQ11,Q9H4A6,O43752,Q9P253,Q9UNK0,Q5JRA6,Q9UEU0,Q9BSR8 32 +O glycan processing 0.7097503010064524 2.0166797252823887 0.0437289470770589 1.0 0.1303482038899731 7 Q10472,Q8NBI6,O43505,Q4G148 4 +Retina morphogenesis in camera type eye 0.6808720176434239 2.0151324286221075 0.0438907752148909 1.0 0.1307112137786533 4 P54802,Q8NBN7 2 +Cellular transition metal ion homeostasis 0.5282525587300977 2.0114335422100713 0.044279683397717 1.0 0.1315583104643818 23 O75880,P35670,Q8N511,P09601,P05067,Q9NQ11,Q15043,O75027,Q8NEW0,O43819 10 +Positive regulation of mitochondrial calcium ion concentration 0.7086071282666491 2.0108435294647427 0.0443419866560597 1.0 0.1315583104643818 7 Q96AQ8,Q9Y3D6,P51572 3 +Sterol metabolic process 0.4529417122799087 2.010324086672314 0.0443968991962366 1.0 0.1315583104643818 42 P04062,Q9UKR5,P05067,P37268,Q9BQE5,P16435,P00387,Q9NWW5,O75477,Q16850,Q14534,O94905,O75845,Q14739,Q15738,Q15125,O15118,Q15392,Q15800 19 +Regulation of lipase activity 0.6814804411575359 2.008819132649628 0.0445563184477482 1.0 0.131970801645599 11 P16435,P50897,Q99623 3 +Retrograde transport vesicle recycling within golgi 0.6545986727926414 2.0004295278348336 0.0454539025682223 1.0 0.133839907968135 3 Q8TBA6 1 +Very low density lipoprotein particle assembly 0.631317557697932 1.9996864204917937 0.045534135437568 1.0 0.1339873842149316 2 P35610 1 +Ubiquitin dependent erad pathway 0.4709081986812989 1.9995855309558397 0.0455450376184027 1.0 0.1339873842149316 35 Q6NTF9,P46379,P27824,Q9GZP9,O75477,P51572,Q9UBU6,Q9BUN8,Q96A33,Q9Y679,O94905,Q9UBV2,Q96CS3,O76024,Q9UKV5 15 +Regulation of membrane lipid distribution 0.7043215555602748 1.988930482443027 0.0467088766490697 1.0 0.1366721410870136 7 Q96GC9,Q96CP7,Q96AA3 3 +Cellular response to sterol depletion 0.709554379209151 1.984823776319096 0.0471640812141791 1.0 0.1375109969478166 6 Q15363,Q9UKV5,O75477 3 +Response to sterol depletion 0.709554379209151 1.984823776319096 0.0471640812141791 1.0 0.1375109969478166 6 Q15363,Q9UKV5,O75477 3 +Regulation of amyloid precursor protein catabolic process 0.639090529202998 1.9800973570130356 0.0476925900916098 1.0 0.138865846618211 14 Q9NQC3,O75298,O95197 3 +Glycerolipid biosynthetic process 0.4189318882369064 1.975373894736869 0.0482257330451609 1.0 0.1399293163358644 51 Q9Y2B2,Q92604,Q10713,Q9NTJ5,Q96BW9,Q9H490,Q86UL3,Q9NPH0,Q9NX62,Q96N66,Q9UG56,O14735,O43292,Q8NF37,Q6IAN0,Q9NUQ2,Q643R3,O95674,Q96S52,Q92643 20 +Receptor recycling 0.6953928134717774 1.9751533395072456 0.0482507492451027 1.0 0.1399293163358644 8 P49069,P42892,Q15907 3 +Metal ion transport 0.3805351584632519 1.971332944988036 0.0486858054073902 1.0 0.1410030779500635 109 Q4KMQ2,Q8N4V1,P05556,P08195,Q9NWR8,P16615,O76024,Q96ER9,O95202,Q15907,Q15043,P21796,Q96GC9,Q96AQ8,P05023,P30536,Q9HD47,P35670,Q6NXT4,O15173,Q9NRA0,O75027,Q8IYU8,Q9HD20,O75844,Q9UM00,Q8WWC4,Q8N1S5,P27105,P98194,Q8NEW0,Q9H0U3 32 +Hydrogen peroxide biosynthetic process 0.6485336666653427 1.9676490492880216 0.0491084319735093 1.0 0.1419122815064492 3 P00403 1 +Leukocyte migration 0.4105554796867181 1.967436523500834 0.0491329071567951 1.0 0.1419201849201588 53 P04062,Q4KMQ2,Q08722,P60033,P00813,P09601,P05067,Q8N5M9,P35613,Q9H4A6,Q5JRA6,P78310 12 +Aminoglycan metabolic process 0.5783974146056895 1.9635319245901144 0.049584398723339 1.0 0.1428450815825055 18 P54802,Q9Y2C2,O43505,Q96L58,Q7LGA3,Q8NCH0,Q9P2E5,P16278,Q9NX62,Q9NWW5 10 +Detection of external biotic stimulus 0.6476873581530358 1.9630652451373676 0.0496385932886227 1.0 0.1429381283582396 3 Q8WTV0 1 +Regulation of autophagy 0.3882070025100747 1.9600995403012225 0.0499841569729164 1.0 0.143742985338854 96 Q86UE4,P27544,Q9H300,O15269,P09601,P07602,P21796,P12235,P30536,Q9NZ45,Q9NZJ7,O00165,P05141,O75396,Q9NQ11,Q9BXS4,O75844,Q93050,O15118,Q07820,Q8N5K1,Q9UBQ0,Q9Y371 23 +Glial cell proliferation 0.7044666541418968 1.9590946499035695 0.0501017032539026 1.0 0.1439541896309314 6 Q96G23,P30536 2 +Cellular lipid metabolic process 0.3614064806838241 1.9585527601033683 0.0501651865100576 1.0 0.1440133012134972 227 O00767,P04062,Q86YN1,P28288,Q96G23,Q9NZD2,P14174,Q6IAA8,Q96BW9,Q5T8D3,Q9HB40,P51648,O95864,O94905,O14735,P17900,Q9NRA0,Q8NBX0,O75844,Q9NUQ2,Q643R3,P50897,Q9BWD1,Q9Y2B2,P27544,Q99623,Q9BT22,Q8N9F7,O95470,O43808,Q9Y394,Q6Y1H2,P07602,Q9NPH0,Q9NX62,Q96AA3,Q9NZJ7,Q9UKU0,Q5SGD2,O43292,Q9H7Z7,Q96DA6,Q9UBV2,Q8NBN7,Q15800,Q53GQ0,P50416,O15269,P23786,Q9NTJ5,Q86UL3,A1L0T0,Q13510,Q9NWW5,Q96N66,O75477,Q9UG56,Q6NUM9,Q53H12,Q6UX07,Q8TC12,Q9P035,Q8NF37,Q96S52,Q9BY49,Q68D91,Q92604,Q99735,P37268,Q10713,P16435,Q2TAA5,Q9H490,Q99805,Q6IAN0,Q8NHP8,Q92643,O00116,Q8NCG7 79 +Cholesterol storage 0.6467915948097211 1.958211017473372 0.0502052568640867 1.0 0.1440615018939596 3 Q8WTV0 1 +Mitophagy 0.6197472464005503 1.9568763617072815 0.0503620063490346 1.0 0.1443843554881415 15 P27544,P05141,Q99623,P21796,P12235 5 +Positive regulation of vacuole organization 0.6855252710165056 1.9502831036195336 0.0511423854019614 1.0 0.1460443971583571 5 Q5VWJ9,O95219,Q9Y371 3 +Copi coated vesicle budding 0.6853473801052272 1.9493639184200595 0.0512519802655999 1.0 0.146165542670964 5 Q15363,P49755,Q8N6H7 3 +Phosphatidylinositol dephosphorylation 0.6676657483868758 1.9457989474105124 0.0516788951282001 1.0 0.1467176751761976 4 Q9NTJ5 1 +Organic hydroxy compound biosynthetic process 0.3924163713715153 1.9454446347890004 0.0517214871187339 1.0 0.1467176751761976 57 P04062,P28288,O14734,Q9UKR5,P37268,O15269,P16435,P00374,P00387,Q13510,O75477,Q16850,Q14534,O94905,O75845,Q14739,Q9NRA0,Q15738,Q9H4L5,Q15125,Q15392,Q15800 22 +Mitochondrial genome maintenance 0.689138859150586 1.942560187371136 0.0520693211860423 1.0 0.1474657391333989 8 P12235,Q9BSK2 2 +Regulation of macroautophagy 0.400331106049872 1.9420743699783525 0.0521280977549418 1.0 0.1475681795942153 55 P04062,P27544,Q9NV70,O15269,O95219,Q5VWJ9,P09601,Q8IYI6,P21796,P12235,P05141,Q9Y487,O75396,Q9NQ11,Q93050,O15118,P36543,Q9UNH7,Q9Y5K8,Q9Y371 20 +Mammary gland development 0.5526178789219783 1.9366580291058164 0.0527871594472639 1.0 0.1489172760897749 20 Q99623,Q86UL3,Q13505,Q9NQC3,P00403 5 +Establishment of protein localization to endoplasmic reticulum 0.5413168938036064 1.9361716755546212 0.052846678308942 1.0 0.1490049233708767 21 P46379,Q9Y5M8,Q9UNL2,P61026,P60468,P49458,Q99442,Q9UGP8,Q15005,Q15629,O43681 11 +Regulation of dna primase activity 0.6655948553054866 1.9348777970761193 0.0530052933903641 1.0 0.1492746140001283 4 P49643,Q9BRT9,Q9Y248 3 +Regulation of hormone metabolic process 0.6820207022486101 1.9321573213527787 0.0533400910868171 1.0 0.1498194319411323 5 P16435,O75844 2 +Entry of bacterium into host cell 0.6414377556984234 1.929143156278351 0.0537130926663851 1.0 0.1503598065721107 3 Q96KP1,Q9UPT5 2 +Regulation of entry of bacterium into host cell 0.6414377556984234 1.929143156278351 0.0537130926663851 1.0 0.1503598065721107 3 Q96KP1,Q9UPT5 2 +Lipophagy 0.6633929331679439 1.9232511733737572 0.0544485133431804 1.0 0.1520923813026453 4 O15269 1 +Regulation of ire1 mediated unfolded protein response 0.6972677856787488 1.9225636526479943 0.0545348724459895 1.0 0.1522033549924838 6 Q96HY6,P57088 2 +Regulation of phospholipase activity 0.6783492621259327 1.9191572661249696 0.0549644339083525 1.0 0.1525327351926394 9 Q99623,P50897 2 +Negative regulation of immune effector process 0.671162099547825 1.9156779732185325 0.0554060978136456 1.0 0.1533888916571158 10 P09601,Q08722 2 +Glycerophospholipid biosynthetic process 0.4304014632038099 1.9135798753326696 0.0556738585005014 1.0 0.1539538013719591 46 Q9Y2B2,Q10713,Q9NTJ5,Q96BW9,Q9H490,Q86UL3,Q9NPH0,Q9NX62,Q96N66,Q9UG56,O14735,O43292,Q8NF37,Q6IAN0,Q9NUQ2,Q643R3,O95674,Q96S52,Q92643 19 +Regulation of ph 0.4910171553804419 1.9115187138750072 0.055937954225731 1.0 0.1541607914664786 25 Q93050,Q05086,O75503,P51790,Q92544,Q8N511,Q9Y6M7,P50897,O75787,P06576,Q15904,Q9NWW5 12 +Regulation of cellular ph 0.4910171553804419 1.9115187138750072 0.055937954225731 1.0 0.1541607914664786 25 Q93050,Q05086,O75503,P51790,Q92544,Q8N511,Q9Y6M7,P50897,O75787,P06576,Q15904,Q9NWW5 12 +Import across plasma membrane 0.5369604131249865 1.905146246160482 0.0567610633292088 1.0 0.1556221005514805 21 P30825,P54709,P33121,P31751,P05556,P08195,Q15758,P11166,Q15043,O75915,Q15041,P55011,P05023 13 +Nuclear membrane organization 0.5008566702671572 1.8942909369336864 0.0581864033313637 1.0 0.1586636762519391 24 O14657,Q9H6H4,Q86XL3,Q6NUK4,P50402,Q9Y3E7,O43633 7 +Acidic amino acid transport 0.6666286238014508 1.8911824915666455 0.058599987708884 1.0 0.1594262777145987 10 O75746,P05556,Q9UJS0,O75915,P55011,Q15041,O60831 7 +Integrated stress response signaling 0.6740538452960854 1.8908177798921275 0.0586486729055295 1.0 0.1594579494907525 5 P57088,Q15363 2 +Cartilage development involved in endochondral bone morphogenesis 0.6566839787936947 1.8877347819416592 0.0590615644668928 1.0 0.1599245592790088 4 O75844 1 +Hormone biosynthetic process 0.6697610871561857 1.8734192802461556 0.0610105096731314 1.0 0.1640348464358329 9 Q53GQ0,P16435,P05023,P30536 4 +C4 dicarboxylate transport 0.6753592962800976 1.8703353497928117 0.061437263565244 1.0 0.1644987708505708 8 O75746,Q15758,Q9UJS0,Q02978,P55011,Q9UBX3 6 +Retinal metabolic process 0.6532567117797836 1.8695381963482527 0.0615479746683511 1.0 0.1645541636203092 4 Q6UX07,Q8NBN7 2 +Inorganic anion transmembrane transport 0.6689452768378468 1.8690628687757231 0.0616140681826855 1.0 0.1646404572642535 9 Q4KMQ2,Q9UHG3,P51790,Q02978,P55011,Q9UBX3 6 +Cardiolipin metabolic process 0.6747485028682206 1.8671208975177227 0.0618847067539023 1.0 0.1647717822373575 8 Q99623,Q96BW9,Q6UWP7,Q96DA6 4 +Positive regulation of mitochondrion organization 0.508468762806118 1.8630586643964049 0.0624540130169974 1.0 0.1653283848235846 23 P27544,Q9Y3D6,Q96A26,O14737,P21796,P12235 6 +Pinocytosis 0.6794101085187915 1.860494197028648 0.0628156387051772 1.0 0.1659167304782297 7 P50897 1 +Glycosaminoglycan catabolic process 0.6501023092663073 1.852758798648132 0.0639169381084852 1.0 0.1666387949742745 4 P16278,P04066,P54802 3 +Aminoglycan catabolic process 0.6501023092663073 1.852758798648132 0.0639169381084852 1.0 0.1666387949742745 4 P16278,P04066,P54802 3 +Cerebral cortex radially oriented cell migration 0.6713660398793264 1.8492999759154856 0.0644145092378603 1.0 0.1672529430791307 8 Q9NQC3,O94901 2 +Telencephalon glial cell migration 0.6713660398793264 1.8492999759154856 0.0644145092378603 1.0 0.1672529430791307 8 Q9NQC3,O94901 2 +Labyrinthine layer blood vessel development 0.6494242381699624 1.8491479583957016 0.0644364509564972 1.0 0.1672529430791307 4 Q15363 1 +Regulation of atp metabolic process 0.4640917719848449 1.847232697896937 0.0647134223408087 1.0 0.1679050958031795 30 Q9Y3D6,Q9BRT2,P14406,P05067,Q9NRA0,O14548,Q9BSK2,P00403,P30536 9 +Maternal placenta development 0.6655729896401826 1.8466069818878563 0.0648041215690116 1.0 0.1680736216140277 5 P35613 1 +Female meiosis i 0.6258064865873554 1.8437409896414816 0.0652208962967075 1.0 0.1684851646319379 3 Q15645 1 +Regulation of mast cell activation 0.6647988402929261 1.8425609136934584 0.0653931451321914 1.0 0.1687662867984633 5 O95219,Q9NRA0,P09601 3 +Regulation of receptor binding 0.6475471481725856 1.8391448967763997 0.0658938769212922 1.0 0.1696195696144304 4 P16615 1 +Regulation of collateral sprouting 0.6023955594507826 1.83740224171954 0.0661505361417813 1.0 0.1701460598634943 2 P53990 1 +Amide transport 0.4318501648857351 1.8367419958130295 0.066247992440277 1.0 0.1703296158527484 43 Q8N183,Q9NZJ7,Q03519,Q9BRT2,Q15907,P07602,P50416,Q8N5M9,Q9H2D1,Q9NZD2,O00400 11 +Posttranslational protein targeting to membrane translocation 0.6465675340159819 1.8339202850464495 0.0666658279636691 1.0 0.1706519272080756 4 P60468,Q9UGP8 2 +Cellular monovalent inorganic cation homeostasis 0.4620492044562832 1.829764085340976 0.0672852233695679 1.0 0.1718458286997417 30 Q93050,Q05086,O75503,P51790,Q92544,Q8N511,Q9Y6M7,P50897,O75787,P06576,Q15904,Q9NWW5,P05023 13 +Protein targeting to membrane 0.44592650201868 1.8189358382444976 0.0689212194165531 1.0 0.1751550854493921 37 P40855,P46379,Q15629,Q9Y3D6,O00560,Q9UNL2,P60468,P49458,P56589,P27105,O60725,Q9UGP8,P43307,Q5BJH7,Q15041,O43681 16 +Alcohol metabolic process 0.3800585862489427 1.815295009409153 0.0694785855324933 1.0 0.1764123712003564 88 P04062,P05067,P37268,Q9BQE5,O15269,Q10713,Q8N9F7,P16435,Q9Y394,P00374,P51648,Q9NX62,P00387,Q13510,Q9NWW5,O75477,Q16850,Q14534,O94905,Q6NUM9,O75845,Q6UX07,Q9NRA0,Q8TC12,Q14739,Q15125,O15118,Q9BW91,Q9BY49,Q15392,Q8NBN7,Q15800 32 +Purine containing compound transmembrane transport 0.658406314717299 1.8126045919276248 0.069892829070371 1.0 0.1767765936347859 9 Q8TB61,P12235,O43808,P12236 4 +Long chain fatty acyl coa metabolic process 0.6519352857476448 1.811350776201755 0.0700865704150222 1.0 0.1770608094695297 10 Q6Y1H2,Q9UKU0 2 +Phospholipid biosynthetic process 0.3786264580499556 1.8104441350066391 0.0702269402621769 1.0 0.1770901151312476 63 Q9Y2B2,Q86YN1,Q92604,O15269,Q10713,Q9NTJ5,Q96BW9,Q9H490,Q86UL3,Q9NPH0,Q9NX62,Q96N66,Q9UG56,O14735,Q9NRA0,O43292,Q8NF37,Q6IAN0,Q9NUQ2,Q643R3,Q96S52,Q92643 22 +Threonine catabolic process 0.5965527315220649 1.8042671512855877 0.0711894367340288 1.0 0.1786996428779451 2 P52758 1 +Retinol metabolic process 0.6628333439197662 1.8041956633093827 0.0712006389591812 1.0 0.1786996428779451 8 Q9Y394,Q6UX07,Q8NBN7,Q6NUM9 4 +Ire1 mediated unfolded protein response 0.668233431143164 1.8022902801396743 0.0714997469814753 1.0 0.1792374862107865 7 Q96HY6,P57088 2 +Carbohydrate derivative biosynthetic process 0.3541873712008588 1.8021333613005373 0.0715244260054195 1.0 0.1792374862107865 174 O75746,Q9Y2B2,Q86YN1,O14734,Q7LGA3,P56385,Q53GQ0,Q9BT22,Q9UJZ1,Q92542,P53007,Q8NBI6,Q2TAA5,Q4G148,P00813,Q9UJS0,P00846,Q6Y1H2,P46977,Q8WVQ1,Q9H490,P49915,O75947,Q8TB61,P09622,Q10472,Q96AA3,Q6ZXV5,Q99805,Q9UKU0,O43505,Q9BYC5,Q9UIJ7,Q9NQX7,Q8NCH0,Q9H4A6,Q9NRA0,Q13126,Q8NBX0,O43292,Q9BXS4,O60476,O75964,P00403,Q8WVC6,Q9Y673,Q9Y2C2,Q8NAT1,P24539,Q96L58,Q9UMR5,O15118,Q96S52,P50897,Q9P2E5,Q92643,P06576,Q9H0U3 58 +Regulation of lipid metabolic process 0.37595129075677 1.801956692391989 0.0715522195259359 1.0 0.1792374862107865 58 Q92604,Q99623,Q96G23,P50416,Q6IAA8,P16435,P07602,Q13510,P05023,P30536,Q96N66,Q9NZJ7,O75477,P60033,O94905,Q8NF37,O75844,Q9H6K4,Q96DA6,Q8NCG7 20 +Chloride transmembrane transport 0.6733817542887399 1.800309455887164 0.0718117886504468 1.0 0.1796658783646675 6 Q9UHG3,P55011,P51790,Q4KMQ2 4 +Alcohol biosynthetic process 0.435778356559015 1.7947790773553316 0.0726889056025725 1.0 0.1803252665723058 40 P16435,P04062,O75477,Q15125,P00374,Q16850,O94905,O75845,P37268,Q13510,Q14739,P00387,Q9NRA0,Q15392,Q15800,O15269,Q15738 17 +Pigment granule localization 0.6556628915527098 1.7946815682700392 0.072704448841347 1.0 0.1803252665723058 5 Q15907,Q13561 2 +Peroxisome organization 0.6209627080107574 1.7889966948629226 0.0736153478428234 1.0 0.1822377666734741 13 P40855,P28288,Q9Y3D6,O14734,O75192,O75381 6 +Amyloid beta metabolic process 0.606258507364544 1.7859952322687265 0.0741000301025689 1.0 0.1829519653969629 14 P49755,Q9NQC3,O75298,O95197 4 +Protein catabolic process in the vacuole 0.6453541539035217 1.7753785676561855 0.0758354004102397 1.0 0.18582754084121 10 P60033,Q96RL7,Q8N511,Q9NQ11,O14773,P13473 6 +Regulation of leukocyte degranulation 0.6573717297818271 1.7752143606230308 0.0758624994396177 1.0 0.18582754084121 8 O95219,P09601,Q12846,P30511,Q9NRA0,P11279 6 +Secondary alcohol metabolic process 0.422554513590738 1.7742350918817678 0.076024271921782 1.0 0.1860841571448794 44 P16435,P04062,O75477,Q15125,Q16850,Q14534,O15118,O94905,P05067,O75845,P37268,Q9BQE5,Q14739,P00387,Q15800,Q15392,Q15738,Q9NWW5 18 +Mitotic nuclear membrane organization 0.6681722259491484 1.773435900764764 0.0761565045402681 1.0 0.1863379541375076 6 Q9H6H4,Q6NUK4 2 +Heparan sulfate proteoglycan biosynthetic process 0.6676182727519566 1.77057395289522 0.0766315765502934 1.0 0.1867483822381403 6 Q96L58,Q7LGA3 2 +Heparan sulfate proteoglycan metabolic process 0.6676182727519566 1.77057395289522 0.0766315765502934 1.0 0.1867483822381403 6 Q96L58,Q7LGA3 2 +Glycerolipid metabolic process 0.3775547894516954 1.770502643097262 0.0766434444761161 1.0 0.1867483822381403 73 Q9Y2B2,Q92604,Q99623,P50416,Q6UWP7,Q9UJZ1,Q10713,Q9NTJ5,Q8N9F7,Q96BW9,Q9H490,Q86UL3,Q9NPH0,Q9NX62,Q96N66,Q9UG56,O14735,Q53H12,O43292,Q8NF37,Q6IAN0,Q9NUQ2,Q643R3,O95674,Q96DA6,Q96S52,Q9UBV2,Q92643,Q8NCG7 29 +Regulation of secretion 0.3760744607421683 1.7665475974971232 0.077304023588582 1.0 0.1878088539262602 89 Q8N183,Q9BRT2,Q9Y5U9,P50416,P16615,Q9NV70,Q9Y3E7,P14174,O43633,P00813,P09601,P49755,P11279,Q96KC8,Q92783,O00560,Q16850,Q9NQ11,Q9H4A6,Q9NRA0,P61026,Q9P253,Q8N5M9,P30511,Q9UNH7 25 +Cell recognition 0.4610523473561267 1.7655716913208783 0.0774677328156543 1.0 0.1879960445429708 26 P60033,P45880,P35613,Q9NQC3,Q9Y639 5 +Regulation of organic acid transport 0.6430779345635936 1.7629061638435102 0.0779163172937376 1.0 0.1883882362970194 10 P33121,Q9Y3D6,P05556,O75915,P55011,P14174,Q15041 7 +Mitochondrial fusion 0.5729598588978254 1.761322156904333 0.0781838919626458 1.0 0.1888913570437276 16 Q9NX63,Q9Y3D6,Q8TB36,O60313,O95140,Q9H300,Q8IWA4,Q9Y6C9 8 +Negative regulation of exocytosis 0.6647034389984651 1.7555010020686277 0.0791736494056707 1.0 0.1905772799853313 6 P09601 1 +Protein import 0.375623118974563 1.7546048201826066 0.0793269264063913 1.0 0.1907352396246493 87 Q92973,P40855,O14925,Q99623,Q99595,P56589,Q9NS69,O60830,Q9Y512,Q3ZCQ8,O14737,Q7Z4Q2,P52292,Q9HD47,Q8TEX9,Q8NFH5,P13473,Q15388,O96008,Q96DA6,O75381,O43615 22 +Amyloid beta formation 0.6286925344864125 1.754373408339137 0.0793665447257445 1.0 0.1907602371022314 12 P49755,Q9NQC3,O75298,O95197 4 +Outer mitochondrial membrane organization 0.6473225071033191 1.75076336459739 0.0799866795827395 1.0 0.1916861396167854 5 Q9NS69,O14737 2 +Chemical homeostasis 0.35196116628714 1.7485723337715005 0.080364972071903 1.0 0.1922398452493159 194 Q8N183,O15260,P04062,Q05086,Q96A33,P51790,P05067,O75787,Q9NWR8,Q9NQC3,P16615,Q16891,O76024,O43819,Q6IAA8,Q9Y639,P52789,O95202,Q92544,P09601,Q15907,P30519,Q96AQ8,Q9NWW5,P05023,P30536,Q9HD47,P35670,P51572,Q8N511,Q9NQ11,Q9BWH2,O75027,Q8IYU8,Q9P035,Q9HD20,Q8NF37,Q8NE01,Q9Y6C9,Q9UM00,O75880,Q93050,Q96CP7,Q9Y3D6,Q8WWC4,O15118,P50897,Q8N5M9,P06576,P98194,Q8NEW0 51 +Nervous system process 0.3627426994142396 1.7408988702267096 0.0817013067960463 1.0 0.1944389831442182 111 P04062,Q05086,P05067,O60443,Q9Y5J9,O14773,O76024,Q92542,Q9Y6M9,Q9Y639,P07196,Q9Y5L4,Q14108,Q14118,P36383,Q9NWW5,O60313,O00264,Q9Y5J7,O43924,O75844,Q13641,Q9BPZ3,Q9H6K4,Q96DA6,P50897,Q96HR9,Q8NBU5,Q9UKV5,Q9H0U3 30 +Endochondral bone morphogenesis 0.6617384944449569 1.7401453419496882 0.0818335002803318 1.0 0.1946826129118099 6 O75844,Q9NX62 2 +Apoptotic mitochondrial changes 0.4388672104965266 1.7332142551681446 0.0830575942394007 1.0 0.1963132905431258 36 Q9Y3D6,Q3ZCQ8,Q96A26,P05141,O60313,Q9H3K2,O14737,P45880,Q9H300,P12235 10 +Cellular response to unfolded protein 0.4450084356804507 1.7314315467689003 0.0833748241100793 1.0 0.1968799600020945 33 Q96HY6,Q15363,Q6NTF9,Q9BUN8,Q9GZP9,Q9Y4P3,O76024,P57088,Q9UKV5,P48723 10 +Salivary gland development 0.6274419536480764 1.7313436782203282 0.0833904855094656 1.0 0.1968799600020945 4 Q14118 1 +Hepatocyte differentiation 0.5834063686824523 1.729292785520014 0.0837567071941716 1.0 0.1970319944373187 2 Q16822 1 +Neutrophil clearance 0.5834063686824511 1.7292927855200078 0.0837567071941727 1.0 0.1970319944373187 2 P09429 1 +Negative regulation of alpha beta t cell differentiation 0.5834063686824511 1.7292927855200078 0.0837567071941727 1.0 0.1970319944373187 2 P09429 1 +Neutrophil homeostasis 0.5834063686824511 1.7292927855200078 0.0837567071941727 1.0 0.1970319944373187 2 P09429 1 +Regulation of cd4 positive alpha beta t cell differentiation 0.5834063686824511 1.7292927855200078 0.0837567071941727 1.0 0.1970319944373187 2 P09429 1 +Negative regulation of cd4 positive alpha beta t cell differentiation 0.5834063686824511 1.7292927855200078 0.0837567071941727 1.0 0.1970319944373187 2 P09429 1 +Golgi vesicle budding 0.6527689141239993 1.7211775740892905 0.0852186059563906 1.0 0.1989653289282253 7 Q15363,P49755,Q8N6H7,Q9H4A6 4 +Monovalent inorganic cation homeostasis 0.4436249087457164 1.7191409079667603 0.0855887175538836 1.0 0.1995439814970544 33 Q05086,P51790,O75787,Q9Y5X3,Q92544,Q9NWW5,P05023,Q8N511,Q9Y6M7,Q9Y487,P55011,Q93050,P54709,O75503,P50897,P06576,Q15904,Q9BXP2,Q93063 19 +Regulation of protein folding 0.623955411404377 1.7125283713970674 0.0867993407455662 1.0 0.2015745629267366 4 O14737 1 +Cerebral cortex cell migration 0.6390479600037167 1.7080406949005806 0.0876287917431988 1.0 0.2027075664420984 9 Q9NQC3,O94901 2 +Purine nucleoside biosynthetic process 0.6554075725817786 1.707278102721429 0.087770374128294 1.0 0.202963160577224 6 P00813 1 +Fatty acid transport 0.539692161490859 1.705306136469684 0.0881373437168528 1.0 0.2035233745255096 18 P28288,P33121,Q9Y3D6,O43808,O14975,P11166,P50416,P14174,P23786 9 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.6216504135211764 1.7000700620666782 0.089117747756424 1.0 0.2038651386196684 4 P18031 1 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.6216504135211764 1.7000700620666782 0.089117747756424 1.0 0.2038651386196684 4 P18031 1 +Regulation of necrotic cell death 0.625126662370113 1.6979616024621924 0.0895150091603866 1.0 0.2042692686320619 11 Q13510,P12235,P00403 3 +Triglyceride metabolic process 0.6247692349044074 1.6959581376181845 0.0898938082447444 1.0 0.2046832159824526 11 Q96N66,Q92604,Q9UBV2,P50416,Q86UL3 5 +Lung alveolus development 0.6362730997728997 1.6922795584901051 0.0905926834661701 1.0 0.205929627615412 5 P00813 1 +Maternal process involved in female pregnancy 0.641731471601322 1.6917508811720312 0.090693482541067 1.0 0.2060447242517349 8 Q9BQE5,P35613 2 +Organic cation transport 0.6521293183646759 1.69021705086392 0.0909864374779763 1.0 0.2062359249500796 6 Q70HW3,O43808 2 +Bone morphogenesis 0.6465901650223073 1.688585250040456 0.0912989392729632 1.0 0.2068365011119117 7 P16435,O75844,Q9NX62,Q92896 4 +Sulfur compound transport 0.6224535211509081 1.6829686551139595 0.0923811594999914 1.0 0.2086145824015691 11 Q9HC21,Q70HW3,Q8TB61,O00400,Q9UBX3 5 +Release of cytochrome c from mitochondria 0.5257132331043571 1.6770773797668566 0.0935273514673742 1.0 0.2106785888126359 19 Q9Y3D6,Q3ZCQ8,Q96A26,Q9H3K2,O60313,Q9H300 6 +Amyloid precursor protein biosynthetic process 0.6325927216626444 1.6727247975223556 0.0943814852293052 1.0 0.2116419950229137 5 Q9NQX7 1 +Cellular modified amino acid catabolic process 0.6265647588100576 1.6719589618859931 0.09453241469042 1.0 0.2118460704081916 10 Q9UHG3,Q8NBM8 2 +Retrograde transport endosome to golgi 0.4252369510548423 1.671282227601795 0.0946659451590143 1.0 0.2120725085786018 39 O15260,O43752,O95249,P49257,O75503,Q9UBQ0,O60499,Q13190,O60749,P20340,Q9UEU0,Q9UNH7,Q9UID3 13 +Membrane lipid catabolic process 0.6139986048389423 1.670813067615374 0.0947586065949057 1.0 0.2122072671874939 12 O95470,P04062,Q99735,P50897,Q13510 5 +B cell homeostasis 0.6480732446509095 1.6690688905445263 0.095103727763278 1.0 0.2124699297873644 6 P49069,P00813 2 +Walking behavior 0.6318152224095613 1.668589035126068 0.0951988533950702 1.0 0.2125369750215522 5 Q8N2K0,O75844,O15118 3 +Positive regulation of mitochondrial membrane potential 0.6314819029237023 1.6668155026715592 0.0955510966583248 1.0 0.2131047348771932 5 Q9UJZ1,Q8IWA4 2 +Terpenoid metabolic process 0.5139872123495055 1.6651836239253652 0.0958761270877681 1.0 0.2137566112120732 20 Q9Y394,Q6NUM9,Q9BY49,Q6UX07,Q8TC12,P51648,Q8NBN7 7 +Negative regulation of vascular associated smooth muscle cell proliferation 0.6300386630030543 1.659132820421766 0.0970890310249736 1.0 0.2155772770513701 5 P09601 1 +Lipoprotein biosynthetic process 0.6116958020711063 1.6576565963674357 0.0973867991542125 1.0 0.2158803692966849 12 Q9Y2B2,Q96S52,Q92643,Q9H490,O43292 5 +Negative regulation of secretion 0.5421487457123757 1.6576363727266674 0.0973908835138996 1.0 0.2158803692966849 17 Q16850,P00813,P09601,P30511,Q8N5M9 5 +Glial cell migration 0.5982243347508207 1.6562056818883355 0.0976801729978014 1.0 0.21592568943783 13 Q96G23,Q9NQC3,O94901,P30536 4 +Iron ion transport 0.6173847981810804 1.6544805537051932 0.0980299112696734 1.0 0.2162797431061195 11 O15173,Q8N4V1,Q15907 3 +Protection from natural killer cell mediated cytotoxicity 0.5702600058428389 1.6537500365046622 0.0981783114815342 1.0 0.2162797431061195 2 P04439 1 +Detection of other organism 0.5702600058428389 1.6537500365046622 0.0981783114815342 1.0 0.2162797431061195 2 P04439 1 +Regulation of dendritic cell differentiation 0.5702600058428365 1.653750036504648 0.0981783114815371 1.0 0.2162797431061195 2 P09429 1 +Dendritic cell differentiation 0.5702600058428365 1.653750036504648 0.0981783114815371 1.0 0.2162797431061195 2 P09429 1 +Antigen processing and presentation of endogenous antigen 0.6282992870203274 1.6495139573628133 0.0990423861633189 1.0 0.2173716197180237 9 P30511,P10321,Q9NZ08,Q03519 4 +Antigen processing and presentation of endogenous peptide antigen 0.6282992870203274 1.6495139573628133 0.0990423861633189 1.0 0.2173716197180237 9 P30511,P10321,Q9NZ08,Q03519 4 +Regulation of cysteine type endopeptidase activity 0.3811971959005366 1.6443612489586787 0.100101604573779 1.0 0.21928297807303 53 Q6IC98,P16435,Q9NZJ7,Q9Y3D6,Q9NR28,Q96A26,Q9P0J0,Q9BXK5,O14737,Q15392,Q15041 11 +Calcium ion transport 0.3624706095981849 1.6414924671993978 0.1006952294771299 1.0 0.2202876870062682 58 P98194,Q4KMQ2,Q9UM00,P08195,O95202,Q8WWC4,Q9NWR8,Q9NRA0,P16615,O76024,P21796,Q96GC9,Q8IYU8,O75844,Q96AQ8,P30536 16 +Response to topologically incorrect protein 0.3623702814909437 1.6402890282052431 0.1009450858119902 1.0 0.2205386613723803 58 Q96HY6,P46379,Q9GZP9,O76024,P57088,P48723,Q15363,Q9Y679,Q92575,Q9Y4P3,P18031,Q15629,O14657,Q6NTF9,Q7Z2K6,Q9BUN8,O95140,Q96CS3,Q9UKV5 19 +Response to mitochondrial depolarisation 0.6373110160482642 1.6394457026628977 0.10112047005898 1.0 0.2206264801286847 7 P52789,P04062,O43464,O95140,Q9UII2 5 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.637311016048264 1.6394457026628957 0.1011204700589805 1.0 0.2206264801286847 7 P52789,P04062,O43464,O95140,Q9UII2 5 +Mucopolysaccharide metabolic process 0.6078260488212712 1.635511196780497 0.1019419294292243 1.0 0.2221959650464027 12 Q9Y2C2,O43505,Q96L58,Q8NCH0,Q9P2E5,P16278,Q9NX62 7 +Regulation of histone h3 k14 acetylation 0.5661700262927367 1.6301351458701772 0.1030729370921363 1.0 0.2235520438179883 2 Q969T9 1 +Actin modification 0.5658778848963006 1.6284463606588453 0.10343027412434 1.0 0.2239840737212947 2 Q86TU7 1 +Peroxisome fission 0.6348889666307282 1.62658178338561 0.1038259508395584 1.0 0.2239840737212947 7 P40855,O75192,Q9Y3D6 3 +Regulation of reactive oxygen species biosynthetic process 0.62362397624942 1.6239555348116823 0.104385298784414 1.0 0.225116362888885 9 P51790,Q9BSK2,O75027,P00403 4 +Nucleobase containing small molecule biosynthetic process 0.6342538738551475 1.6232061614649094 0.1045453411587953 1.0 0.2252960772159359 7 P00813 1 +Glycosyl compound biosynthetic process 0.6342538738551475 1.6232061614649094 0.1045453411587953 1.0 0.2252960772159359 7 P00813 1 +Lipid translocation 0.6392327022153967 1.6228271278025337 0.1046263648959335 1.0 0.2253290034023286 6 Q96GC9,Q96AA3 2 +Ribonucleoside metabolic process 0.6233626041862671 1.62252491435826 0.1046910029594458 1.0 0.2253290034023286 9 P00813,Q13126 2 +Purine ribonucleoside metabolic process 0.6233626041862671 1.62252491435826 0.1046910029594458 1.0 0.2253290034023286 9 P00813,Q13126 2 +Cotranslational protein targeting to membrane 0.5787452388888468 1.620347732662643 0.105157600744564 1.0 0.2259064575023949 14 Q9UNL2,P60468,P49458,P43307,Q9UGP8,Q15041,Q15629 7 +Negative regulation of smooth muscle cell proliferation 0.6336080893781101 1.6197726356289357 0.1052811265333624 1.0 0.2260773664505887 7 P09601,P09493 2 +Nonribosomal peptide biosynthetic process 0.6220875401134753 1.6167073108214365 0.1059414750766103 1.0 0.2266009008191717 5 Q9UJ14 1 +Antigen processing and presentation 0.4537354920095048 1.6101221042808789 0.1073712023879207 1.0 0.2285315718578275 25 P04062,Q03519,Q9NZ08,P61026,P10321,P30511,P20340,Q9BZG1 8 +Negative regulation of cd4 positive alpha beta t cell activation 0.5835768556399765 1.6091602796804494 0.1075812991993359 1.0 0.2287591925645813 3 P78540,P09429 2 +Positive regulation of isotype switching to iga isotypes 0.5623721881390683 1.6081602658825496 0.1078000829612897 1.0 0.2291497693166067 2 O96028 1 +Srp dependent cotranslational protein targeting to membrane translocation 0.6046453279231521 1.6076948647679832 0.1079020238150212 1.0 0.2292303999275988 4 Q15629 1 +Triglyceride biosynthetic process 0.6362608694454354 1.607237788873335 0.1080022153910711 1.0 0.2292303999275988 6 Q86UL3,Q8WTV0,P33121,Q92604 4 +Positive regulation of t cell mediated cytotoxicity 0.6362576403415012 1.6072208378852348 0.1080059324834408 1.0 0.2292303999275988 6 P30511 1 +Regulation of t cell mediated cytotoxicity 0.6362576403415012 1.6072208378852348 0.1080059324834408 1.0 0.2292303999275988 6 P30511 1 +Vitamin transmembrane transport 0.636250989125232 1.607185922640608 0.1080135891815707 1.0 0.2292303999275988 6 Q9HC21,Q9H2D1 2 +Regulation of leukocyte migration 0.4354004755628856 1.5990859056792948 0.1098015159443384 1.0 0.2316267763721479 30 Q4KMQ2,Q08722,P60033,P00813,P09601,P05067,Q5JRA6 7 +Regulation of phosphatidylinositol 3 kinase signaling 0.6188827994259722 1.5979756497463788 0.1100483964017824 1.0 0.2320400296223629 9 Q05086,O00165 2 +Ribonucleoside triphosphate biosynthetic process 0.4334291590252674 1.5962992492973775 0.1104219976309861 1.0 0.232752599462408 31 O75746,P24539,Q9UJS0,P00846,P56385,Q9NRA0,P06576,Q9UJZ1,O75964,P00403 10 +Autophagosome maturation 0.4939641145975582 1.593619720766318 0.1110212347432051 1.0 0.2337138408267149 21 P56962,O95721,P16615,Q96GC9,P13473,Q9UEU0,O43633 7 +Regulation of cardiac conduction 0.6172874286840665 1.5910143087569686 0.1116063556162973 1.0 0.2348698547592486 5 Q6PI78 1 +Maintenance of protein location in cell 0.4831723785561219 1.5895463757743955 0.1119370926359626 1.0 0.235414091729241 22 P52789,P24390,O15258,O94901,Q96RL7,Q9H4A6,O43292,P30536 8 +Embryonic body morphogenesis 0.5799076690585105 1.5885248573280573 0.1121677047387856 1.0 0.2357471914149365 3 Q14118 1 +Protein processing 0.3654905673729431 1.5877190663262883 0.1123498796746647 1.0 0.2358263712270775 56 Q96TA2,Q9Y366,O75787,Q9H300,Q92542,Q9UJZ1,Q99797,Q10713,P67812,P42892,Q6NXT4,Q2T9J0,Q5JRX3,Q12797,Q9UG56,Q96F07,Q9BXS4,O75844,O75503,O43464,Q92896,Q15392,Q15005 23 +Androgen metabolic process 0.6321898384226047 1.5858465017764256 0.1127741340658796 1.0 0.2363005424117196 6 O95470 1 +Primary alcohol metabolic process 0.5219375482990838 1.5846260723168517 0.1130513175793119 1.0 0.2365786669481669 18 Q8N9F7,Q9Y394,Q6NUM9,Q6UX07,Q8TC12,P51648,Q8NBN7 7 +Positive regulation of lipid catabolic process 0.5999762783481246 1.5821921404583867 0.1136057140588076 1.0 0.2373086669918079 4 P50416,Q8NCG7 2 +Lysosomal protein catabolic process 0.6159823108459961 1.582052008760096 0.1136376980723639 1.0 0.2373086669918079 9 Q96RL7,Q8N511,Q9NQ11,O14773,P13473 5 +Regulation of blood pressure 0.4919925347196154 1.5791118747298751 0.1143103984305649 1.0 0.2380281597941715 21 P29992,Q9Y5X3,P09601,Q9NZ08,O75787,Q9HB40,P20020,P42892,Q6RW13,Q93063,P42785,P05023,P09493 13 +Pigment biosynthetic process 0.4607386285584951 1.578523660504293 0.1144453569014407 1.0 0.2381136663098255 24 P00813,Q9P0S9,Q7KZN9,O00264,O75027,P22830 6 +Regulation of receptor localization to synapse 0.6146055384415863 1.5766333213380894 0.11487992100438 1.0 0.2388662923121436 5 O15400,Q14118 2 +Phosphatidylinositol biosynthetic process 0.4495761882418892 1.5759564939605957 0.115035829944027 1.0 0.2389290161866397 25 Q9Y2B2,Q9NTJ5,Q96N66,Q96S52,Q9H490,Q92643,Q9NX62,O43292,Q10713 9 +Very long chain fatty acid metabolic process 0.6033920585533472 1.5754441009889515 0.1151539716501408 1.0 0.2390983228155596 11 P28288,Q9UKU0,Q15067,Q6Y1H2,O14975,Q9P035 6 +Regulation of lysosomal protein catabolic process 0.5983287233137539 1.5731791237667372 0.1156773477984576 1.0 0.2397275321994702 4 Q9NQ11 1 +Positive regulation of chemokine production 0.6244950287910915 1.5712057895753937 0.1161348557201598 1.0 0.2402218713202316 7 P09601,P05067 2 +Positive regulation of anion transport 0.6293162850971128 1.5707227052438524 0.1162470728401672 1.0 0.2402218713202316 6 P55011,P14174,Q15041,P05556 4 +Phosphatidylinositol metabolic process 0.4347258213534024 1.5668127667063876 0.1171584623846444 1.0 0.241569943918812 28 Q9Y2B2,Q9NTJ5,Q96N66,Q92604,Q96S52,O14735,Q9H490,Q92643,Q6UWP7,Q9NX62,O43292,Q10713 12 +Regulation of blood circulation 0.4327794051744389 1.562618199177135 0.1181424250547831 1.0 0.2429847986003857 29 P78310,Q9HD47,P00813,P16615,P42892,O75844,P05023,P09493,Q6PI78 9 +Membrane protein proteolysis 0.5822270634866522 1.5617757238507433 0.1183408326332995 1.0 0.2430865183858336 13 Q16740,Q9H300,Q9NZ08,Q14118 4 +Response to activity 0.5414506637461265 1.5589588354412005 0.1190061234423318 1.0 0.2442993628401076 16 Q9UDX5,Q15388 2 +Forebrain cell migration 0.6060517368700327 1.5578838193720612 0.1192607915318963 1.0 0.2446077399712276 10 Q9NQC3,O94901 2 +Intermembrane lipid transfer 0.6205399407530691 1.5500624133421832 0.1211265364030567 1.0 0.2476349041241762 7 Q9NZD2 1 +Granulocyte differentiation 0.6154232086989719 1.5498439617574469 0.121178972520505 1.0 0.2476349041241762 8 Q8N5M9,Q6IAN0,Q14739,O00165 4 +Regeneration 0.4141577309710845 1.5445555129860007 0.1224538138493493 1.0 0.2490711853201976 38 P60033,P00374,P09601,Q96G23,P50416,Q14118,P07196,P30536 8 +Natural killer cell degranulation 0.5923641294946062 1.5404898129477025 0.1234410040560374 1.0 0.2501002093351372 4 P11279 1 +Natural killer cell activation involved in immune response 0.5923641294946062 1.5404898129477025 0.1234410040560374 1.0 0.2501002093351372 4 P11279 1 +Embryonic heart tube development 0.6186617108599795 1.5400080938975294 0.1235583805073279 1.0 0.2502273693957928 7 Q15363,P42892 2 +Positive regulation of monooxygenase activity 0.6077500822820432 1.5397896872050134 0.123611626536928 1.0 0.2502273693957928 5 P00374 1 +Golgi ribbon formation 0.6234452424514206 1.5397604318180995 0.1236187601564693 1.0 0.2502273693957928 6 Q9H4A6,Q9Y3A6 2 +N glycan processing 0.6074210117694594 1.5380181914546274 0.1240441669161787 1.0 0.2509916266927359 5 Q9BYC5 1 +Endoplasmic reticulum to cytosol transport 0.578200917352624 1.5378850158507047 0.1240767316418645 1.0 0.2509916266927359 13 Q9BUN8,Q9GZP9,P51572,Q9Y679,Q9UBV2,Q96CS3,Q8NBM4 7 +Leukocyte adhesion to vascular endothelial cell 0.5907609218128111 1.531687593262924 0.1255995454458509 1.0 0.2521260248064314 4 Q9H4A6 1 +Leukocyte tethering or rolling 0.5907609218128111 1.531687593262924 0.1255995454458509 1.0 0.2521260248064314 4 Q9H4A6 1 +Cerebellar purkinje cell layer development 0.616581599241212 1.5288630212710237 0.1262984051132831 1.0 0.2532952345866398 7 O14949,P04062,Q96D53 3 +Cd4 positive alpha beta t cell activation 0.6165317969546164 1.5285960557431748 0.1263646144301531 1.0 0.2533501851965724 7 P60033,Q9UJZ1 2 +Mast cell activation involved in immune response 0.6164823644256776 1.5283310663666667 0.1264303603727146 1.0 0.2533918199706391 7 O95219,P09601,Q9NRA0,Q9UNH7,Q99584 5 +Positive regulation of anion transmembrane transport 0.5898548478452751 1.526709992516282 0.1268331415333141 1.0 0.2536280992221104 4 Q15041,P05556 2 +Body fluid secretion 0.5491033006534843 1.5204359724322667 0.1284014393043135 1.0 0.2553944533146127 15 Q13505,P00813,Q86UL3,P00403 4 +Vitamin transport 0.6086619313140482 1.5130827732890162 0.13025863480755 1.0 0.2579097264251401 8 P04062,Q9HC21,Q8WTV0,P11166,Q9H2D1 5 +Response to oxygen levels 0.3544438474291911 1.5122275949398538 0.130475973270669 1.0 0.2582413565472259 64 Q96A26,P00813,P00846,P09601,Q8N511,P30519 6 +Cell migration involved in sprouting angiogenesis 0.6080386203664407 1.5096881135536122 0.1311230257053299 1.0 0.2587663565261311 8 Q5JRA6,P09601 2 +Glycerophospholipid metabolic process 0.3549468295204751 1.5095981758801873 0.1311459871008138 1.0 0.2587663565261311 66 Q9Y2B2,Q92604,Q99623,Q6UWP7,Q9UJZ1,Q10713,Q9NTJ5,Q8N9F7,Q96BW9,Q8N2K0,Q9H490,Q86UL3,Q9NPH0,Q9NX62,Q96N66,Q9UG56,O14735,O43292,Q8NF37,Q6IAN0,Q9NUQ2,Q643R3,O95674,Q96DA6,Q96S52,Q92643 26 +Skeletal muscle cell differentiation 0.6025430075684755 1.5079810802932272 0.1315593693414785 1.0 0.2591313380186254 9 P50402 1 +Cytosolic calcium ion transport 0.4519204976401431 1.5078608961763325 0.1315901325875832 1.0 0.2591313380186254 24 Q8WWC4,O95202,Q8IYU8,P16615,P21796,Q96AQ8 6 +Positive regulation of leukocyte degranulation 0.6126325049883241 1.507675352069665 0.1316376368250409 1.0 0.2591467108546041 7 O95219,Q12846,P30511,Q9NRA0,P11279 5 +Positive regulation of mitochondrial translation 0.6018152651851529 1.5039568784829196 0.1325924701801524 1.0 0.26047657097082 9 Q9BRT2,Q9Y2R0,Q6P087,Q567V2 4 +Negative regulation of leukocyte mediated immunity 0.6116886499222274 1.502605874514097 0.132940707628645 1.0 0.2608478820205843 7 P09601 1 +Cellular response to topologically incorrect protein 0.4075497671231892 1.5026035210798336 0.132941314871704 1.0 0.2608478820205843 39 Q96HY6,Q15363,Q6NTF9,P46379,Q9BUN8,Q9GZP9,Q9Y679,Q9Y4P3,P18031,O76024,P57088,Q9UKV5,P48723 13 +Positive regulation of b cell proliferation 0.6007774611026613 1.5021971185979075 0.1330462087649631 1.0 0.2609752556543507 5 P60033,P00813 2 +Nuclear membrane reassembly 0.5720885401581202 1.5015224717247184 0.1332204789098658 1.0 0.2612385960719748 13 Q9H6H4,Q86XL3,O43633,Q6NUK4 4 +Import into cell 0.4257200147600783 1.4888653082426109 0.1365228405097314 1.0 0.2657119866554872 28 P30825,P54709,P33121,P31751,P05556,P08195,Q15758,O14975,P11166,Q15043,O75915,Q15041,P55011,P05023,Q9BXP2 15 +Purine containing compound salvage 0.6091009323364498 1.4886963968502902 0.1365673342587128 1.0 0.2657119866554872 7 P00813 1 +Autophagy of nucleus 0.5395851592170725 1.4754061947048027 0.1401033709247112 1.0 0.2703502232919051 2 O75143 1 +Chloride transport 0.56725173233522 1.4726713807057532 0.1408396671692335 1.0 0.2713699372139187 13 Q9C0H2,Q9UHG3,P51790,Q96S66,P30536 5 +Regulation of anion transmembrane transport 0.6098675418277096 1.467845222274277 0.142146270422879 1.0 0.2734157618353747 6 Q15041,O75915,P05556 3 +Aminoglycan biosynthetic process 0.5843831075347815 1.4671955211972618 0.1423228749676224 1.0 0.2736194928585623 11 Q9Y2C2,O43505,Q96L58,Q7LGA3,Q8NCH0,Q9P2E5 6 +Regulation of protein localization to plasma membrane 0.4218510949738894 1.4671233857304111 0.1423424935275241 1.0 0.2736194928585623 29 Q9HD47,O15400,O15258,P05556,Q9UNK0,O00264,P98194,Q9BXS4,Q9UEU0 9 +Fatty acid transmembrane transport 0.5981242711644169 1.4555672092446663 0.1455122982405639 1.0 0.2778310274683828 8 P28288,P33121,P11166,P50416,P23786 5 +Membrane biogenesis 0.4242183476932527 1.4542956568928358 0.1458643540605131 1.0 0.2781777690058514 26 Q9H6H4,Q96CP7,Q86XL3,O75192,Q12846,Q6NUK4,Q9Y3E7,O43633 8 +Cellular response to fatty acid 0.5918086782580962 1.4536723583616464 0.1460371652322398 1.0 0.2782634601973327 5 P50416,P11802,P13010 3 +Lipid droplet formation 0.5765194700453284 1.4532146611554992 0.1461641627425696 1.0 0.2783489010406398 4 O95674,Q14534 2 +Reactive nitrogen species metabolic process 0.5027933783703084 1.4530512404135645 0.1462095276606241 1.0 0.2783489010406398 18 O43169,P16435,Q08722,P30536 4 +Regulation of long term synaptic potentiation 0.6024513552796027 1.4528827135769282 0.1462563212931034 1.0 0.2783489010406398 7 Q9BPZ3,Q92542,Q9Y639 3 +Aspartate transmembrane transport 0.5760097026369996 1.4503966540413238 0.1469479396297506 1.0 0.279265254702478 4 O75746,Q9UJS0 2 +Regulation of exocytosis 0.4016915342195498 1.4461907452594978 0.148123708775439 1.0 0.2799610041532928 39 O00560,P20339,Q9P253,P09601,Q12846,P30511,Q9NQ11,P11279,P16615,Q9NRA0,P61026,Q9Y3E7,Q92783,O43633 14 +Neuron apoptotic process 0.3730666653710543 1.4460793895600794 0.1481549358317486 1.0 0.2799610041532928 50 P04062,Q9NR28,Q96A26,P09601,P50897,O76024,Q07820,Q01105,Q92542,P07196 10 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.5501565859066069 1.4455531230643148 0.1483025827988444 1.0 0.2799610041532928 14 Q96A26,Q9NZJ7,Q9BXK5 3 +Regulation of anion transport 0.5804484809987134 1.444670232504609 0.1485505350156795 1.0 0.2801900874262802 11 P05556,Q15907,O75915,P55011,P14174,Q15041 6 +Tissue regeneration 0.5957669651375107 1.4426651201623195 0.1491148293689801 1.0 0.2810108562704106 8 P60033,Q14118 2 +Positive regulation of reactive oxygen species biosynthetic process 0.5745239603098575 1.4421799709008725 0.1492516093773928 1.0 0.2811063202584017 4 P00403 1 +Positive regulation of phospholipase activity 0.6042143612352533 1.437780673153945 0.150496294736504 1.0 0.2827685613810026 6 Q99623 1 +Positive regulation of lipase activity 0.6042143612352533 1.437780673153945 0.150496294736504 1.0 0.2827685613810026 6 Q99623 1 +Isoprenoid metabolic process 0.420525572955332 1.432730964163218 0.1519347369862935 1.0 0.284029199039669 27 Q9Y394,Q6NUM9,Q9BY49,Q6UX07,Q8TC12,P51648,Q8NBN7 7 +Reactive oxygen species biosynthetic process 0.5773888808093564 1.4271275723208408 0.1535431263105338 1.0 0.2857267755288383 11 P51790,Q9NRA0,O75027,P00403,Q9BSK2 5 +Spindle assembly involved in female meiosis 0.5308209173239975 1.42395970815614 0.1544581359668284 1.0 0.2865310348370151 2 O95067 1 +Skeletal muscle tissue regeneration 0.5960312403649686 1.4182110759059152 0.1561291491891374 1.0 0.2888101688599289 7 P60033,Q14118 2 +Mannosylation 0.5903014265694713 1.412702710404554 0.1577431543135186 1.0 0.2908890710052682 8 Q2TAA5,Q8NAT1,O43505,Q9BT22,Q6ZXV5 5 +Regulation of animal organ morphogenesis 0.5948765315009601 1.411965639442039 0.1579600787192654 1.0 0.2912068324991145 7 Q99623 1 +Ph reduction 0.5188281433353953 1.4114278608904347 0.1581184926882319 1.0 0.2912521219720029 16 Q93050,Q05086,O75503,P51790,Q8N511,P50897,O75787,Q9NWW5 8 +Leukocyte differentiation 0.34541862166317 1.41094026699319 0.1582622276855343 1.0 0.291378967259063 62 P04062,P24390,Q9BRX8,O00165,P60033,P05141,P00813,P55327,P05067,Q8N5M9,Q14739,Q15904,Q6IAN0,O96005 14 +Lactation 0.5685670127852264 1.4083988745982778 0.1590129922904084 1.0 0.2920165190035956 12 Q13505,Q86UL3,P35670,P00403 4 +Nucleus organization 0.3468674190576946 1.4003562379952006 0.161406667842743 1.0 0.2950609710662074 68 O14657,Q9H6H4,O94901,Q86XL3,Q6NUK4,Q9Y2U8,P50402,Q9NQC3,Q7Z3B4,Q8NFH5,O75844,Q9BTX1,Q9UH99,O43633 14 +Regulation of tor signaling 0.5166930152535679 1.3974163203046466 0.162288414205862 1.0 0.2960097144274566 16 P04062,Q9H4A6,Q6IAA8,O75844 4 +Regulation of heart contraction 0.4151813340992687 1.3970205978564665 0.1624073771462686 1.0 0.2961439547516317 28 P78310,Q9HD47,P00813,P16615,O75844,P05023,P09493,Q6PI78 8 +Calcium ion transmembrane transport 0.3920560648525331 1.3953938398555192 0.1628971079254022 1.0 0.2968499627394014 41 P98194,Q4KMQ2,Q8WWC4,O95202,P16615,Q8IYU8,P21796,Q96GC9,Q96AQ8,Q9UM00 10 +Regulation of toll like receptor signaling pathway 0.5771540761955002 1.3952814727623108 0.1629309767915556 1.0 0.2968499627394014 10 Q6IC98 1 +Steroid hormone biosynthetic process 0.591596253302914 1.3942083840224595 0.1632546869124909 1.0 0.2972738064615733 7 Q53GQ0,P30536 2 +Vesicle targeting rough er to cis golgi 0.5766362171436445 1.392349077270817 0.1638167167585538 1.0 0.2978817623954984 10 P49755,Q9NR31 2 +Nucleoside triphosphate metabolic process 0.3737707788345495 1.3903484538613182 0.1644230909210673 1.0 0.2987347446514688 48 O75746,Q9H773,P24539,P00813,Q9UJS0,P00846,O60313,P56385,Q8IWA4,Q9NRA0,P06576,O75947,Q9UJZ1,O75964,P00403 15 +Regulation of response to endoplasmic reticulum stress 0.4569273490046017 1.3896619701086876 0.1646315481699638 1.0 0.2988639450649399 22 Q96HY6,P46379,P51572,O60313,Q4ZIN3,P18031,O76024,P57088 8 +Ribonucleoside triphosphate metabolic process 0.3957959749096037 1.3891610228185172 0.1647837910879992 1.0 0.2989435483261079 39 O75746,P24539,Q9UIJ7,Q9UJS0,P00846,O60313,P56385,Q8IWA4,Q9NRA0,P06576,O75947,Q9UJZ1,O75964,P00403 14 +Homologous chromosome pairing at meiosis 0.5810535981824834 1.3886139846652474 0.1649501625414584 1.0 0.2989435483261079 9 Q9BTX1,Q92791,O94901,Q15645 4 +Cdp diacylglycerol metabolic process 0.5808892779993832 1.3876971510289813 0.1652292839305669 1.0 0.2993662962805276 9 Q96BW9,Q9NUQ2,O95674,O14735,Q86UL3 5 +Myeloid leukocyte migration 0.4139974241717432 1.3866625739189915 0.1655446779574023 1.0 0.2996220378571635 28 Q4KMQ2,Q08722,P60033,Q8N5M9,P35613,P78310 6 +Cell volume homeostasis 0.5901979159275841 1.386631928040171 0.1655540273515301 1.0 0.2996220378571635 7 P55011,P51790,Q4KMQ2,Q96ER9 4 +Tor signaling 0.4563688986647678 1.3853747773154097 0.1659378993543039 1.0 0.3001588114610011 22 P04062,Q9H4A6,O75844,Q9NWS0,Q6IAA8 5 +Negative regulation of neuron projection development 0.4658889629803485 1.385359467927742 0.165942578211206 1.0 0.3001588114610011 21 Q05086,Q9NQX7,Q96G23,P08670,Q9NQC3 5 +Iron ion homeostasis 0.5013068908295311 1.3834539932127805 0.1665257047665873 1.0 0.3010467462520859 17 Q8N511,P09601,Q9NQ11,Q15043,O75027,Q15904,P30519 7 +Regulation of steroid metabolic process 0.539789897259599 1.3815631994344144 0.1671058600409278 1.0 0.3019283294622688 14 P16435,O75477,Q13510,Q6IAA8,P05023,P30536 6 +Long chain fatty acid transport 0.5393993833873043 1.3791469298823629 0.1678494568299808 1.0 0.3026854293331809 14 P28288,P33121,O14975,P11166,P50416,P14174,P23786 7 +G2 mi transition of meiotic cell cycle 0.522348816827355 1.3740422239056436 0.1694285743499661 1.0 0.3051116505811252 2 O95067 1 +Regulation of release of cytochrome c from mitochondria 0.5506854305773653 1.3733687103545935 0.1696377519024852 1.0 0.3054040938829077 13 Q96A26,Q9H300,O60313,Q9H3K2 4 +Chemokine production 0.5782116052351178 1.3727487258849846 0.1698304756818063 1.0 0.3055825097163262 9 P09601,P05067 2 +Dense core granule transport 0.5211802512416053 1.367143493302544 0.1715803328644967 1.0 0.3077133002580863 2 P33176 1 +Anterograde neuronal dense core vesicle transport 0.5211802512416053 1.367143493302544 0.1715803328644967 1.0 0.3077133002580863 2 P33176 1 +Mating 0.5602684100807395 1.363090354295779 0.1728540363344726 1.0 0.30923200105679 4 P00813 1 +Regulation of glycoprotein metabolic process 0.5489524229918042 1.3629395623209757 0.1729015589159004 1.0 0.30923200105679 13 Q99805,P62820,Q9H0U4,Q9NQX7,Q9BXS4,Q92542 6 +Muscle hypertrophy in response to stress 0.5401538203796974 1.362641260024565 0.1729955986304223 1.0 0.30923200105679 3 P16615 1 +Lysosomal lumen acidification 0.5855561099871109 1.3614534410415962 0.1733704375261082 1.0 0.3098171957761935 7 O75787,Q9NWW5,Q8N511,P50897 4 +Negative regulation of leukocyte apoptotic process 0.5898588456228615 1.3611360491431497 0.1734706992737171 1.0 0.3098267373074762 6 P00813 1 +Negative regulation of lymphocyte apoptotic process 0.5898588456228615 1.3611360491431497 0.1734706992737171 1.0 0.3098267373074762 6 P00813 1 +Leukocyte degranulation 0.5482939733491491 1.3589751179623792 0.174154473460957 1.0 0.3108869093402506 13 O95219,P09601,Q12846,P30511,Q9NRA0,P11279,Q9UNH7,Q99584 8 +Regulation of bone mineralization 0.57439687822139 1.358959153862147 0.1741595323923555 1.0 0.3108869093402506 5 O75844,Q4KMQ2 2 +Antigen processing and presentation via mhc class ib 0.5591367609169239 1.3567933936537653 0.1748468672125707 1.0 0.311943249293157 4 Q03519 1 +Glycosphingolipid metabolic process 0.5646129014085098 1.3536333952223731 0.1758533671001561 1.0 0.3131398746398852 11 Q99805,P04062,P17900,Q9NZD2,Q9NWW5 5 +Sarcoplasmic reticulum calcium ion transport 0.5832717377075749 1.3490467777156172 0.1773219415710816 1.0 0.3149816254997125 7 O75844 1 +Vacuolar transport 0.3518118720534867 1.347703414494004 0.1777537934360784 1.0 0.315319772704 54 Q9NZJ7,Q96RL7,Q9P253,Q96ED9,Q9UNK0,O15118,P07602,Q9NQ11,Q9UEU0,P11279,Q14108,P13473,Q9Y3E7,Q92783,O43633 15 +Regulation of oxidative phosphorylation 0.5728854647644447 1.3429701069556823 0.1792816535374002 1.0 0.3172541703150308 9 O14548,Q9BSK2,P14406 3 +Regulation of antigen receptor mediated signaling pathway 0.5772841029494922 1.3410836581334873 0.1798932924522605 1.0 0.3176476638161635 8 P00813 1 +Regulation of t cell receptor signaling pathway 0.5772841029494922 1.3410836581334873 0.1798932924522605 1.0 0.3176476638161635 8 P00813 1 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.5557994804391901 1.338208419824843 0.1808285051671434 1.0 0.3183742702105231 4 Q92783 1 +Regulation of regulated secretory pathway 0.4773388259400858 1.3363594570162871 0.1814318112756179 1.0 0.318970319294999 19 O95219,P20339,Q9P253,P09601,Q12846,P30511,P11279,P16615,Q9NRA0 9 +Thyroid hormone mediated signaling pathway 0.5147531405200229 1.3291449721889457 0.183800145584192 1.0 0.3215886760583236 2 P42785 1 +T cell apoptotic process 0.5535615162273878 1.3205351595361932 0.1866564051902197 1.0 0.3259745888394207 12 P00813 1 +Protein localization to endoplasmic reticulum exit site 0.5670996967998116 1.3190833802042323 0.1871412387550246 1.0 0.326449497611969 5 Q5JRA6,P51572 2 +Negative regulation of macroautophagy 0.5586094666599137 1.318972277289242 0.1871783807539215 1.0 0.326449497611969 11 P09601,O75396 2 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.5121238679520927 1.313574139256114 0.1889895561830106 1.0 0.3286424674381175 2 P23396 1 +Collagen biosynthetic process 0.5650322375199442 1.3077678113339466 0.1909520750745525 1.0 0.3313490553127802 5 P08670 1 +Phosphatidylglycerol biosynthetic process 0.5501888673167804 1.3069149506572928 0.1912415978965649 1.0 0.3316667892259917 4 Q96BW9 1 +Positive regulation of protein localization to cell surface 0.5795872721761987 1.30605332113308 0.1915344253860496 1.0 0.3319184308256256 6 Q9HD47,Q92544 2 +Entry into host 0.3993264550382155 1.304435133776972 0.1920852626194116 1.0 0.3326963635923372 32 P35232,P05556,P60033,Q9P253,O15118,P35613,P11279,Q14108,Q14118,P78310 10 +Positive regulation of mast cell activation 0.5482963485213016 1.296346199867643 0.1948562384169245 1.0 0.3365136307898633 4 O95219,Q9NRA0 2 +T cell cytokine production 0.5482478814815691 1.2960754520434397 0.1949494913252427 1.0 0.3365444280427074 4 P60033 1 +Mitochondrial protein processing 0.5777153674929125 1.2959950816879515 0.1949771793593013 1.0 0.3365444280427074 6 Q9UJZ1,Q99797,Q96TA2,Q10713 4 +Zinc ion homeostasis 0.5734158114226775 1.2954069772313437 0.1951798723873972 1.0 0.3366486714615594 7 Q8NEW0,Q9NQ11,P35670 3 +Regulation of reactive oxygen species metabolic process 0.4011162949317974 1.2953363720785327 0.1952042171779808 1.0 0.3366486714615594 30 P52789,P51790,P00374,Q9H300,O75027,Q9BSK2,P00403,P30536 8 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.5475351580649657 1.292093538746772 0.1963247532229552 1.0 0.3380659427695732 4 P42892 1 +Calcium mediated signaling 0.4707919920442706 1.2895701073941253 0.1971999601343586 1.0 0.3391257480919633 19 Q9Y3D6,O75844,P00813,P16615 4 +Neuron projection regeneration 0.5481336017296379 1.2886298221877006 0.1975268105273626 1.0 0.3395089571149614 12 P00374,Q96G23,Q14118,P30536 4 +Calcium mediated signaling using intracellular calcium source 0.5467964515034007 1.287965519532439 0.197757966125057 1.0 0.3397205430608401 4 Q9Y3D6 1 +Ether biosynthetic process 0.5610738852866872 1.2860822306137238 0.1984143648843672 1.0 0.3404965757006176 5 Q6IAN0 1 +Regulation of t cell differentiation 0.5517782125697631 1.2794419660586387 0.2007414636764009 1.0 0.3434067806288116 11 P00813 1 +Generation of precursor metabolites and energy 0.3254409700158164 1.278321546632008 0.201136073618829 1.0 0.3438115445361916 198 O14949,P21912,P04062,O95168,Q9BRT2,Q99623,P05067,O96000,P56385,Q9BRR6,Q9UDW1,O14548,O43819,Q9Y6M9,P52789,P13073,O43676,P16435,P22695,Q9P0J0,P00846,O95139,P14406,Q7KZN9,P22830,P12235,Q13423,Q9NZ45,P20674,P03886,P03915,P08574,O75964,O95167,P00403,P14927,P24539,Q9H3K2,P06576,O14957,Q15070,Q9Y375,Q9BSK2 43 +Negative regulation of endoplasmic reticulum unfolded protein response 0.558892466440435 1.2741201998249945 0.2026208206277311 1.0 0.3459871088301933 5 Q96HY6,O76024 2 +Establishment of planar polarity involved in neural tube closure 0.5054046158340764 1.273718202225637 0.2027633032015203 1.0 0.3461398648795828 2 Q13308 1 +Maintenance of protein localization in organelle 0.484632961533731 1.2698705415698166 0.2041307480274086 1.0 0.3479283350190401 17 P52789,O94901,O15258,P24390,O43292,P30536 6 +Cognition 0.3871332678649504 1.267759922505495 0.2048836983800543 1.0 0.3487563971381994 37 Q05086,Q9BPZ3,P50897,Q9UKV5,P17900,P05067,Q8NBU5,O00264,Q9H0U3,Q92542,Q9Y639,Q13641 12 +Negative regulation of tubulin deacetylation 0.5042360502483347 1.26677786614432 0.2052347285406592 1.0 0.3488145153550307 2 Q13131 1 +Positive regulation of oxidoreductase activity 0.5680692214438459 1.2662381828885052 0.2054278211221558 1.0 0.3488145153550307 7 P00374 1 +Visual behavior 0.5574162553615719 1.2660208696883948 0.2055056106089841 1.0 0.3488145153550307 5 Q9Y639,P05067 2 +Vesicle targeting to from or within golgi 0.5324001196481294 1.2629781260116582 0.2065970408916491 1.0 0.3503027228417364 13 Q15363,Q9NR31,Q8N6H7,P49755,Q9HCU5 5 +Nuclear pore organization 0.5320519688618868 1.2608692775690566 0.2073559487401159 1.0 0.3513157626201602 13 Q9BTX1,Q9NQC3,Q7Z3B4,Q8NFH5 4 +Neurotransmitter metabolic process 0.5411370044293343 1.256308892824036 0.2090039989606444 1.0 0.3535254304550474 4 P21964 1 +Lipid droplet organization 0.561591302020276 1.254312550835674 0.2097284238020806 1.0 0.3544155191768011 8 Q96CS3,O95674,Q9Y679,Q14534 4 +Connective tissue development 0.3999821967648924 1.253902416822492 0.2098774764862654 1.0 0.3545756124488459 27 Q96HY6,P16435,O75844,O15173,Q15043,Q9NX62,Q6IAN0 7 +Amyloid fibril formation 0.5655034104443858 1.252223912054398 0.2104882851297638 1.0 0.3553316589933018 7 Q99471,P05067 2 +Nucleoside triphosphate biosynthetic process 0.3854274307822986 1.2514073901574256 0.2107858824151032 1.0 0.3554299818633777 37 O75746,P24539,Q9UIJ7,Q9UJS0,P00846,P56385,Q9NRA0,P06576,O75947,Q9UJZ1,O75964,P00403 12 +Ventricular cardiac muscle tissue development 0.5539528876551129 1.2470055100030104 0.212395477230562 1.0 0.3569088473213668 5 O75844 1 +Cellular response to nutrient 0.5645467594112458 1.2469961757036312 0.2123988998248163 1.0 0.3569088473213668 7 P09601 1 +Export across plasma membrane 0.5500162990426548 1.2408640047415145 0.2146559919425179 1.0 0.3597623402826077 10 P54709,P08183,P35670,Q4KMQ2,P20020,P05023,P33527 7 +Carbohydrate transport 0.4545669133423446 1.2344022747467152 0.2170530418142606 1.0 0.362821824829522 20 L0R6Q1,O75298 2 +Acid secretion 0.497808939526747 1.2285628485712623 0.2192357519054431 1.0 0.3646295511946299 2 Q13131 1 +Bile acid secretion 0.497808939526747 1.2285628485712623 0.2192357519054431 1.0 0.3646295511946299 2 Q13131 1 +Phospholipase c activating g protein coupled receptor signaling pathway 0.4978089395267349 1.2285628485711904 0.2192357519054701 1.0 0.3646295511946299 2 P29992 1 +Phospholipase c activating dopamine receptor signaling pathway 0.4978089395267349 1.2285628485711904 0.2192357519054701 1.0 0.3646295511946299 2 P29992 1 +Regulation of excretion 0.4978089395267339 1.228562848571185 0.2192357519054721 1.0 0.3646295511946299 2 Q9Y5X3 1 +Negative regulation of platelet derived growth factor receptor signaling pathway 0.4978089395267339 1.228562848571185 0.2192357519054721 1.0 0.3646295511946299 2 Q07954 1 +Positive regulation of exocytosis 0.4620398894707733 1.2268173884852651 0.2198912337840393 1.0 0.3653474100641915 19 O95219,O00560,P20339,Q12846,P30511,Q9NQ11,P11279,Q9NRA0,Q92783,O43633 10 +Endosome organization 0.3921115111400255 1.2260452738670138 0.2201816382795021 1.0 0.3657368281650355 31 Q92783,O43752,Q12768,Q2M389,P51790,Q9BTU6,Q96ED9,Q8IYI6,Q9P253,Q14108,Q9BRG1,Q9Y3E7,Q6IAA8,P61020,O43633 15 +Peptide catabolic process 0.5372414946346938 1.2244331342707342 0.2207888761939274 1.0 0.3661864288094406 12 Q9UJ14,O14773,Q9NZ08 3 +Ubiquinone metabolic process 0.5550384988231214 1.21795924086847 0.2232394620745914 1.0 0.3694061364823657 8 Q96D53,Q8NI60,Q9Y5Z9 3 +Photoreceptor cell development 0.5337492882115089 1.2149094285282354 0.2244006373363254 1.0 0.3704723026173626 4 P54802,Q8NBN7 2 +Regulation of gliogenesis 0.5355232113368382 1.214286607011137 0.2246382981420231 1.0 0.3705935835913893 12 Q96G23,Q14118 2 +Regulation of pattern recognition receptor signaling pathway 0.4157369317679639 1.2138782108787969 0.2247942345399889 1.0 0.3707340963881118 24 Q6IC98,Q9NQC3 2 +Feeding behavior 0.5583628730905981 1.2131716012024176 0.2250642193606138 1.0 0.3707340963881118 7 P50416,Q9GZP9 2 +Regulation of endoplasmic reticulum unfolded protein response 0.5534714385489078 1.2092563547702653 0.2265643730591047 1.0 0.3725471605364825 8 Q96HY6,P57088,O76024 3 +Positive regulation of meiotic cell cycle 0.4934268185802076 1.2024685810594855 0.2291820319978761 1.0 0.3756214674572271 2 P30307 1 +Vesicle docking involved in exocytosis 0.5499927999142549 1.1899254767738745 0.2340756840281663 1.0 0.381820606030952 8 P61026,Q9UEU0 2 +Positive regulation of muscle contraction 0.5435034584431374 1.1895300455191802 0.2342311550766056 1.0 0.3819246404554558 5 P00813 1 +Negative regulation of protein targeting to mitochondrion 0.5099081337269116 1.1884501793878406 0.2346560969043549 1.0 0.382063331825051 3 P49257 1 +Negative regulation by host of viral process 0.5093512565750966 1.1852292471169756 0.2359268191221475 1.0 0.3835940909662214 3 P17980,Q9H1E3 2 +Positive regulation of regulated secretory pathway 0.5490440145775728 1.184650358506705 0.2361557173674087 1.0 0.3837798299334832 8 O95219,Q12846,P30511,Q9NRA0,P11279 5 +Er associated misfolded protein catabolic process 0.5529972599221172 1.1837814035119745 0.2364996054859927 1.0 0.3842277655064115 7 Q9BUN8,P46379 2 +T cell differentiation 0.4114692806740441 1.1788485847788968 0.2384584740953357 1.0 0.3862672255320972 24 P00813,O96005 2 +Response to increased oxygen levels 0.5387652170993471 1.176462617208301 0.2394100623093167 1.0 0.3873008989318997 10 P00846 1 +Regulation of protein secretion 0.3677102844668553 1.1732491355308972 0.2406959131472419 1.0 0.388637873120256 42 Q8N183,Q9Y5U9,Q16850,P49755,P50416,Q9NQ11,Q9H4A6,Q8N5M9,Q96KC8 9 +Nucleotide binding oligomerization domain containing 2 signaling pathway 0.4884604148407859 1.1728618245423117 0.2408512206481539 1.0 0.3886963580695052 2 Q96RT1 1 +Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway 0.4884604148407859 1.1728618245423117 0.2408512206481539 1.0 0.3886963580695052 2 Q96RT1 1 +Positive regulation of long term synaptic potentiation 0.5261076683682635 1.1720086542620318 0.2411935816071597 1.0 0.3890367333220764 4 Q9Y639 1 +Negative regulation of lipid biosynthetic process 0.5464113493968613 1.1700073805657951 0.2419979987152782 1.0 0.3898723927969735 8 Q8NF37,P05023,O75477 3 +Positive regulation of cell killing 0.5417892891608493 1.168086492943147 0.2427718780748196 1.0 0.3908500328827778 9 P30511,P11279 2 +Positive regulation of smoothened signaling pathway 0.5453003039791399 1.1638252859136713 0.2444948226883543 1.0 0.392828501725222 8 P16435,Q9BZG1,Q96J42 3 +Positive regulation of nucleotide biosynthetic process 0.5241997481165039 1.161286591091802 0.2455253706743343 1.0 0.3939994148874273 4 P00403 1 +Positive regulation of atp biosynthetic process 0.5241997481165039 1.161286591091802 0.2455253706743343 1.0 0.3939994148874273 4 P00403 1 +Phospholipid metabolic process 0.3309047778796497 1.155319216156005 0.2479597296498743 1.0 0.3968579926129715 86 Q9Y2B2,Q86YN1,Q92604,Q99623,P37268,Q6UWP7,Q9UJZ1,O15269,Q10713,Q9NTJ5,Q8N9F7,Q96BW9,Q9H490,Q86UL3,Q9NPH0,Q9NX62,Q96N66,Q9UG56,O14735,Q9NRA0,O43292,Q8NF37,Q6IAN0,Q9NUQ2,Q643R3,O95674,Q8NHP8,Q96DA6,Q96S52,Q92643 30 +Endosomal transport 0.3307752317921727 1.1552808089346216 0.2479754521857093 1.0 0.3968579926129715 82 O15260,P49257,Q9Y3E7,Q6IAA8,Q9UID3,O43633,O95249,Q15907,P20340,Q92783,Q15057,O60499,Q13190,O60749,P61026,O43752,O75503,Q15904,Q9UBQ0,Q9UEU0,Q9UNH7 21 +Cardiac ventricle development 0.4918777010633901 1.1548934822762824 0.2481340487914938 1.0 0.396883336570172 15 O75844,Q6PI78 2 +Homologous chromosome segregation 0.5349634797541443 1.1546622932839077 0.2482287463470989 1.0 0.396883336570172 10 Q9BTX1,Q92791,O94901,Q15645 4 +Sodium ion homeostasis 0.5476846749849344 1.1546483057754329 0.2482344765955901 1.0 0.396883336570172 7 P54709,Q9Y5X3,P55011,Q93063,P05023 5 +Negative regulation of cell growth 0.3892253972068217 1.151458946365101 0.2495434753554712 1.0 0.3983907574273702 26 P35232,Q9P0J0,P50897,O14681,Q9NQC3 5 +Regulation of oxidoreductase activity 0.4912880814765027 1.151088123414706 0.249695983499669 1.0 0.3985367677960487 15 P06280,P16435,P00374,Q9BQ95,Q99623,Q8WTV0,Q9NRA0,Q8TCT9,Q15070 9 +Receptor metabolic process 0.3674917041172312 1.1502690006536629 0.2500330944291731 1.0 0.3989772770554001 41 Q9NUN5,P05556,O00560,P49069,P60033,Q9BYC5,Q15907,P18031,P30533,P42892,Q8NBU5,Q6IAA8,Q9Y371 13 +Dephosphorylation of rna polymerase ii c terminal domain 0.5029222676797046 1.1480177881452531 0.2509612206035094 1.0 0.4002626064255338 3 Q9NP77,Q9NQG5 2 +Determination of adult lifespan 0.5491049768780841 1.141636250903343 0.2536052491997766 1.0 0.4031223095150706 6 O75844 1 +Intestinal epithelial cell development 0.4826175869120782 1.1379915743286653 0.2551240006235116 1.0 0.4044316357625749 2 P04818 1 +Intestinal epithelial cell differentiation 0.4826175869120782 1.1379915743286653 0.2551240006235116 1.0 0.4044316357625749 2 P04818 1 +Cellular iron ion homeostasis 0.5006238727650276 1.1374891127963829 0.2553338733305772 1.0 0.4046660658174333 14 Q8N511,P09601,Q9NQ11,Q15043,O75027,Q15904 6 +Regulation of fatty acid transport 0.5481533424926273 1.1364856306024955 0.2557533760221391 1.0 0.4050180489966325 6 P14174,P33121,Q9Y3D6 3 +Nuclear pore complex assembly 0.5361884818777453 1.1364401853618915 0.2557723855966665 1.0 0.4050180489966325 9 Q9BTX1,Q9NQC3 2 +Phospholipid transport 0.4768668203035775 1.1338213180888046 0.2568695068465798 1.0 0.4061138630889981 16 Q4KMQ2,Q8WTV0,Q9BZF1,Q14108,Q9NZD2,Q96GC9,P33527 7 +Paranodal junction assembly 0.4817411627227604 1.132757912952266 0.2573159300620899 1.0 0.4065242960903493 2 O15228 1 +Positive regulation of protein localization to membrane 0.3828699463974151 1.1310848999681626 0.2580193591741964 1.0 0.4072413870138187 30 Q9HD47,Q9Y3D6,O15258,P05556,P60033,O14737,O00264,P27105,P98194 9 +Positive regulation of nucleotide metabolic process 0.5431886337206808 1.1299704395159966 0.2584886806218347 1.0 0.4077849461332375 7 P00403,P05067 2 +Positive regulation of atp metabolic process 0.5431886337206808 1.1299704395159966 0.2584886806218347 1.0 0.4077849461332375 7 P00403,P05067 2 +Necrotic cell death 0.4640243304059234 1.1284973646148508 0.2591099292281196 1.0 0.4086662522351207 17 Q13510,P00403,P12235,P30536 4 +Centriole assembly 0.5344895942698212 1.1268344857860757 0.2598124669333734 1.0 0.4096753101790005 9 O75665,P41208 2 +Protein localization to golgi apparatus 0.530059834063969 1.1265188478628485 0.2599459673016897 1.0 0.4097145854998081 10 Q96RL7,P49755,Q9H4A6 3 +Insulin secretion involved in cellular response to glucose stimulus 0.5341106207533778 1.1246913528996103 0.2607198472059002 1.0 0.410548955267648 9 Q8N183,Q8N5M9,Q15907 3 +Cellular response to biotic stimulus 0.3733909198400111 1.1197927738530715 0.2628020793299839 1.0 0.4130922161969985 36 Q86UE4,Q9UM00,Q96A33,P08670,O75844,P30536 6 +Srp dependent cotranslational protein targeting to membrane 0.5287609151477637 1.1190598441526272 0.2631146094388916 1.0 0.413451912571223 10 P49458,Q9UGP8,Q9UNL2,Q15629 4 +Cartilage development 0.4850693871640715 1.11092224980899 0.2666018173903652 1.0 0.417486399905459 15 Q96HY6,P16435,Q15043,Q9NX62,O75844 5 +Negative regulation of keratinocyte proliferation 0.5150540777550581 1.109840971085524 0.2670675606890909 1.0 0.4176151753463969 4 O14936,P58107,Q9Y3B8 3 +Photoreceptor cell differentiation 0.5282638257980433 1.105483818737747 0.2689500020846607 1.0 0.4203157351948646 5 P54802,Q8NBN7 2 +Regulation of lysosomal lumen ph 0.5303299729006249 1.1033044963471954 0.2698949546592986 1.0 0.4211987243643082 9 O75787,Q9NWW5,Q8N511,P50897 4 +Vesicle cargo loading 0.4950712519830099 1.1026654728289762 0.2701724660476232 1.0 0.4214303126305578 14 Q15363,Q96PC5,Q9NR31,P49755,Q5JRA6 5 +Negative regulation of endoplasmic reticulum calcium ion concentration 0.5262345605732854 1.094277814722297 0.2738331522959885 1.0 0.4259442950694793 5 Q9Y3D6 1 +Regulation of epidermal growth factor activated receptor activity 0.5120105406539298 1.0927059024404024 0.2745229474092707 1.0 0.4260784119561863 4 Q9UNH7,P05067 2 +Renal filtration 0.4932787843366402 1.092125359704304 0.2747780041702481 1.0 0.4262214913461369 3 P43121,Q0IIM8 2 +Positive regulation of extracellular matrix organization 0.5256664356129971 1.091140057081531 0.2752112591815601 1.0 0.426639539286921 5 Q14118 1 +Regulation of lipoprotein metabolic process 0.5110827444565127 1.0874812734834585 0.2768241701971636 1.0 0.4285293296293773 4 P04062,Q9H2M9 2 +Regulation of protein lipidation 0.5110827444565127 1.0874812734834585 0.2768241701971636 1.0 0.4285293296293773 4 P04062,Q9H2M9 2 +Regulation of peptidase activity 0.3259063378705511 1.086734464330434 0.277154178086145 1.0 0.4287854966206532 86 Q96HY6,Q6IC98,P16435,Q9NZJ7,Q9Y3D6,Q9NR28,P61289,Q96A26,P51572,Q9P0J0,Q9BXK5,O14737,P49755,Q15392,Q9UL46,Q92542,Q15041 17 +Camera type eye morphogenesis 0.517609689852975 1.0805949228711098 0.279877341966281 1.0 0.4319241816444166 11 P54802,Q8NBN7,O95140,Q15555 4 +T cell differentiation in thymus 0.5218782404948742 1.0795120811439178 0.2803595111062378 1.0 0.4324638205343857 10 P00813 1 +Pattern recognition receptor signaling pathway 0.3732554991666315 1.0771069748934206 0.2814324773989103 1.0 0.433891233120967 33 Q6IC98,O43657,Q9NQC3 3 +Genitalia development 0.5369459322055093 1.0757755697004447 0.2820276407766395 1.0 0.4346261659560677 6 Q96DA6 1 +Positive regulation of tor signaling 0.5292911604802507 1.074617559294296 0.2825459870365274 1.0 0.4351168208007669 8 Q9H4A6,Q6IAA8 2 +Regulation of programmed necrotic cell death 0.5287141843631353 1.0713989635068757 0.2839900787063949 1.0 0.4367225521308235 8 P12235 1 +Regulation of lymphocyte apoptotic process 0.5324913083487816 1.071190494514488 0.2840837847570605 1.0 0.4367637651658246 7 P00813 1 +Protein o linked glycosylation 0.4480949429500777 1.070528572507888 0.2843814550022268 1.0 0.4371184690969004 18 Q8NBI6,Q8NAT1,O43505,Q4G148,Q10472,Q6ZXV5 6 +Sensory perception of mechanical stimulus 0.4402174881288675 1.0695531787884227 0.2848204798971174 1.0 0.4374842571219724 19 O60443,Q9Y5J9,Q14108,Q9Y5J7,Q9Y6M9 5 +Regulation of protein localization to cell periphery 0.3695967357277438 1.0690309111794416 0.2850557410127512 1.0 0.4376396701155315 35 Q9HD47,O15400,O15258,Q9UNK0,O00264,Q14118,Q9BXS4,Q9UEU0 8 +Regulation of golgi organization 0.528115467883721 1.0680589095344586 0.2854939395272027 1.0 0.4381063557201644 8 Q9P2W9 1 +Head morphogenesis 0.5213413276260064 1.0672468166575804 0.2858603968419113 1.0 0.4384437919075676 5 O95470 1 +Response to thyroxine 0.4706397896581977 1.0664127075805516 0.2862371197639 1.0 0.4386281497227087 2 O94826 1 +Response to l phenylalanine derivative 0.4706397896581977 1.0664127075805516 0.2862371197639 1.0 0.4386281497227087 2 O94826 1 +Regulation of nucleotide binding oligomerization domain containing signaling pathway 0.4886031560490854 1.0650033328137878 0.2868744215619263 1.0 0.4391923602148815 3 Q96RT1,P98170 2 +Heart process 0.3717111345439007 1.0627276744443863 0.2879054668955145 1.0 0.4404542244541658 33 P78310,Q9HD47,P00813,P16615,O75844,P05023,P09493,Q6PI78 8 +Neutral lipid biosynthetic process 0.5309268979789383 1.062588641760596 0.2879685401302665 1.0 0.4404542244541658 7 Q86UL3,Q8WTV0,P33121,Q92604 4 +Endothelial cell proliferation 0.4468720944732501 1.0619014610927735 0.2882804217256201 1.0 0.440661604612197 18 P09601 1 +Cellular response to oxygen levels 0.3671896770553913 1.0604128444891945 0.288956821254978 1.0 0.4415519965244607 36 Q96A26,Q99623,Q8N511,P09601 4 +Oligodendrocyte development 0.5264522753184173 1.058779571581128 0.2897001792843776 1.0 0.4423772562265303 8 P49770,Q92542 2 +Negative regulation of release of cytochrome c from mitochondria 0.5255412925993588 1.05369647591514 0.2920219029044077 1.0 0.4454710020575669 8 Q9H3K2,O60313 2 +Placenta blood vessel development 0.532126846942619 1.049649479379754 0.2938792992698233 1.0 0.4473983362018207 6 Q15363 1 +B cell differentiation 0.5070109064567931 1.0453595949737997 0.2958568036423834 1.0 0.4497795095895386 12 P05141,P00813,P55327 3 +Positive regulation of g protein coupled receptor signaling pathway 0.5170053921007395 1.0432860650685214 0.2968158230184485 1.0 0.4509224325493209 5 P35232 1 +Endocrine process 0.5026290347390934 1.0398587059509743 0.2984055498538165 1.0 0.4526172222928994 4 O75787,P42892 2 +Response to manganese ion 0.5300975819701913 1.0386457885914695 0.2989695022325938 1.0 0.4532449861993432 6 Q9NQ11,P30536 2 +Immune response regulating signaling pathway 0.3156668779152648 1.0376925212774757 0.299413227859884 1.0 0.4538122942812451 62 Q6IC98,O43657,Q08722,Q99623,P00813,Q9NQC3 6 +Multicellular organism aging 0.5144294525221543 1.0366768875494865 0.299886466910984 1.0 0.4542131916461492 10 Q8N5K1,P04062,O75844 3 +Embryonic axis specification 0.515718449850764 1.0361733263493005 0.3001212883523316 1.0 0.4543580172458304 5 Q15363 1 +Liver regeneration 0.514206403914712 1.035393843099746 0.3004850198790598 1.0 0.4546977769519014 10 P09601 1 +Regulation of the force of heart contraction 0.5015982053911512 1.0340502508147438 0.301112671903148 1.0 0.4552906851309205 4 P16615 1 +Positive regulation of natural killer cell mediated cytotoxicity 0.5150935959193006 1.0327197421312533 0.3017350719161646 1.0 0.4556388039483514 5 P11279 1 +Positive regulation of natural killer cell mediated immunity 0.5150935959193006 1.0327197421312533 0.3017350719161646 1.0 0.4556388039483514 5 P11279 1 +Positive regulation of i kappab kinase nf kappab signaling 0.3641862389904269 1.0316066941791917 0.3022564031630201 1.0 0.4562060402363775 36 Q86UE4,O43657,Q7Z7H5,P09601,Q8WVQ1,Q8TB61,Q99584 7 +Regulation of protein localization to chromatin 0.4647969617294787 1.0314702270949785 0.3023203630610553 1.0 0.4562060402363775 2 Q7Z5K2 1 +Negative regulation of glycolytic process 0.4827586206896568 1.0310895960799449 0.3024988061928548 1.0 0.4563698190032254 3 P40763,O75376 2 +Error free translesion synthesis 0.4645048203330605 1.0297229471920897 0.3031400803481805 1.0 0.4571259978084829 2 Q9Y2S7 1 +Progesterone receptor signaling pathway 0.5142914579248717 1.0282862221678404 0.3038152101345566 1.0 0.4580382659950082 5 Q05086 1 +Positive regulation of protein kinase b signaling 0.4343910847624684 1.027433209157833 0.3042165207184577 1.0 0.4582611760239923 19 Q86UE4,P35232,P05556,O00165,Q9NQC3,Q13641 6 +Receptor localization to synapse 0.5039823054282719 1.0273751187274127 0.3042438628811248 1.0 0.4582611760239923 12 P57105,O15400,Q14118 3 +Vascular associated smooth muscle cell proliferation 0.5165648784074088 1.0253582619578778 0.3051941744410911 1.0 0.4592686885088618 9 P09601,P09493 2 +Positive regulation of receptor binding 0.4636283961437456 1.0244810871173191 0.3056080994476935 1.0 0.4593895170639193 2 O14786 1 +Regulation of intracellular lipid transport 0.4636283961437346 1.0244810871172534 0.3056080994477246 1.0 0.4593895170639193 2 P22307 1 +Positive regulation of intracellular lipid transport 0.4636283961437346 1.0244810871172534 0.3056080994477246 1.0 0.4593895170639193 2 P22307 1 +Smad protein signal transduction 0.5154196780084245 1.018870141956309 0.3082646204088934 1.0 0.4622907057269139 9 O00400,P53999,P08670,Q8N1F7 4 +T helper cell lineage commitment 0.4618755477651378 1.0139974080927008 0.3105839890669974 1.0 0.4646633965265952 2 P40763 1 +Positive t cell selection 0.4618755477651378 1.0139974080927008 0.3105839890669974 1.0 0.4646633965265952 2 P40763 1 +Cd4 positive or cd8 positive alpha beta t cell lineage commitment 0.4618755477651378 1.0139974080927008 0.3105839890669974 1.0 0.4646633965265952 2 P40763 1 +T cell selection 0.4618755477651378 1.0139974080927008 0.3105839890669974 1.0 0.4646633965265952 2 P40763 1 +Positive regulation of myotube differentiation 0.4618755477651285 1.013997408092645 0.3105839890670241 1.0 0.4646633965265952 2 Q16539 1 +Glycosyl compound catabolic process 0.5104704448959718 1.0139014941783833 0.3106297583397766 1.0 0.4646633965265952 10 P00813,Q9NUJ1 2 +Antigen processing and presentation of peptide antigen via mhc class i 0.5014182456710176 1.012146749141264 0.3114678928177685 1.0 0.4655970699139897 12 P30511,P10321,Q9NZ08,Q03519 4 +Leukocyte homeostasis 0.4583764885064935 1.0104487282756909 0.3122803520579751 1.0 0.4663843830323637 16 P00813 1 +Regulation of t cell mediated immunity 0.5098415343655911 1.0102832129746278 0.3123596214909847 1.0 0.4663960679536021 10 P60033,P30511 2 +Amyloid beta clearance 0.5097878179457228 1.009974166616287 0.3125076670348286 1.0 0.4665104162824973 10 Q16850 1 +Cardiac chamber development 0.4393710231301399 1.008951158092554 0.3129980586629042 1.0 0.4671356485942932 18 O75844,Q6PI78 2 +Regulation of cellular respiration 0.4393079660894271 1.0085058657459425 0.313211673179691 1.0 0.4673007346931973 18 Q9NZ45,Q9BSK2,P14406 3 +Neural retina development 0.5239488373573324 1.0053003671332612 0.3147522383795533 1.0 0.4688429755587583 6 P20020,P54802,Q8NBN7 3 +Peptidyl asparagine modification 0.5040101125856186 1.001137091679781 0.3167605349303437 1.0 0.4709206950638314 11 Q9Y673,P46977,Q9H0U3 3 +Protein processing involved in protein targeting to mitochondrion 0.4774168544137384 1.000090371324324 0.3172667754094385 1.0 0.471565917548455 3 Q10713 1 +Positive regulation of interleukin 1 production 0.515742945092016 0.9990100324736658 0.3177898313220195 1.0 0.4721283611447755 8 P49755,Q99584 2 +Positive regulation of t cell mediated immunity 0.5111933706184277 0.9949248934257454 0.3197727946346924 1.0 0.4744692779761513 9 P60033,P30511 2 +Learning 0.4372186190909891 0.9937504135804898 0.3203443924396034 1.0 0.4747300192178294 18 Q05086,P50897,P05067,O00264,Q8NBU5,Q9Y639,Q13641 7 +Positive regulation of small molecule metabolic process 0.4558555019004611 0.9936081514748278 0.320413674122818 1.0 0.4747300192178294 16 P16435,Q92604,P05067,P50416,P00403 5 +Regulation of heart rate 0.4872506075376854 0.9880429385094748 0.3231316195743354 1.0 0.4777429408895542 13 Q9HD47,P00813,P16615 3 +Maintenance of location in cell 0.3455465093722623 0.9876727996045128 0.3233129199910958 1.0 0.4778326333941302 44 P35670,P24390,O94901,O95202,Q9H4A6,O43292,Q8NEW0,P30536 8 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.5168238358841181 0.9850164048258296 0.3246160129780562 1.0 0.4790953802225064 7 P18031,O60313,O76024 3 +Behavior 0.3183139760334659 0.98482385249175 0.3247106021302774 1.0 0.4790953802225064 83 P04062,P54802,Q05086,Q9GZP9,P51790,P05067,P50416,O76024,Q92542,Q9Y639,Q9NWW5,P30536,Q96RL7,P17900,Q15154,O00264,O75844,Q13641,Q9BPZ3,O15118,P50897,Q8NBU5,Q9UKV5 23 +Regulation of lymphocyte differentiation 0.4759579091342509 0.982596190960618 0.3258062198499543 1.0 0.4804298629276037 14 P00813 1 +Collagen catabolic process 0.4743680656732277 0.9823997527526098 0.3259029480935029 1.0 0.4804639668370341 3 Q9UBG0 1 +Positive regulation of alpha beta t cell activation 0.5124535954694578 0.9806504199774762 0.3267651613332507 1.0 0.4814787259511762 8 P00813 1 +Cellular extravasation 0.5124226871963926 0.9804779122417514 0.326850267345782 1.0 0.4814787259511762 8 Q08722 1 +Negative regulation of nervous system development 0.4423711075417432 0.979241404110444 0.3274607151743218 1.0 0.4821072504866877 17 Q9NQC3,Q96G23,P30536 3 +Regulation of long term neuronal synaptic plasticity 0.5053653965120892 0.9789513308817142 0.3276040276230354 1.0 0.482209490940964 5 Q9Y639,P05067 2 +Organic hydroxy compound metabolic process 0.3076716625770458 0.9784887926086268 0.327832631674352 1.0 0.4824372000834468 118 O75746,P04062,P28288,O14734,Q9UKR5,P05067,P37268,Q9BQE5,O15269,Q10713,Q8N9F7,P16435,Q9Y394,P00374,P51648,Q9NX62,P00387,P21964,Q13510,Q9NWW5,O75477,Q16850,Q14534,O94905,Q6NUM9,O75845,Q6UX07,Q9NRA0,Q8TC12,Q14739,Q15738,Q9H4L5,Q15125,O15118,Q9BW91,Q9BY49,Q15392,Q8NBN7,Q15800 39 +Response to muramyl dipeptide 0.5047365586017264 0.975476235466414 0.3293240841795044 1.0 0.4837595908019362 5 P08670 1 +Pyridine nucleotide biosynthetic process 0.4731151373465778 0.9751305511081344 0.3294955058434095 1.0 0.4838481228006847 3 Q9BQG2,P43490 2 +Cardiac conduction 0.4195015449736495 0.975055781523688 0.329532590988334 1.0 0.4838481228006847 20 P78310,Q9HD47,P16615,O75844,P05023,Q6PI78 6 +Regulation of protein localization to membrane 0.3353991731695292 0.9734040941637456 0.330352504894625 1.0 0.4844124730635892 48 Q9HD47,O15400,P98194,Q9Y3D6,P05556,O15258,P60033,Q9UNK0,O14737,O00264,Q14118,P27105,Q9BXS4,Q9UEU0 14 +Inositol phosphate metabolic process 0.510933448736078 0.9721663158255296 0.3309678150788939 1.0 0.4848745588535962 8 Q9BW91,Q9NX62 2 +Toll like receptor signaling pathway 0.473923586962521 0.9698092016475456 0.3321416053786845 1.0 0.4861304128472004 14 Q6IC98 1 +Icosanoid biosynthetic process 0.5026879749834535 0.9691269087162624 0.3324818733897117 1.0 0.4864279850936885 10 Q9UJ14,Q9H7Z7,Q8NCG7,Q99735 4 +Response to axon injury 0.4402942045099483 0.9649104090986867 0.3345896873344918 1.0 0.4886773618589594 17 P00374,Q96G23,Q14118,P30536 4 +Viral protein processing 0.501734510996394 0.9636419498270224 0.3352254673643786 1.0 0.4891775319151254 10 Q10472,P27824 2 +Regulation of neurotrophin trk receptor signaling pathway 0.4528191644756065 0.9598443642394464 0.3371335505021169 1.0 0.4909634366840583 2 Q96F07 1 +Positive regulation of neurotrophin trk receptor signaling pathway 0.4528191644756065 0.9598443642394464 0.3371335505021169 1.0 0.4909634366840583 2 Q96F07 1 +Regulation of generation of precursor metabolites and energy 0.3466707200371047 0.958642737011472 0.3377387550450359 1.0 0.4914753885274174 42 Q9NZ45,Q9BRT2,Q99623,Q9H3K2,P14406,P05067,Q9NRA0,O14548,Q9BSK2 9 +Lymphocyte homeostasis 0.4822242861510892 0.9573473850017808 0.3383919457509834 1.0 0.492206466546885 13 P00813 1 +Embryonic digit morphogenesis 0.5081682698241952 0.956735338199502 0.3387008567838871 1.0 0.492546044349569 8 Q9NX62,P42892 2 +Positive regulation of epithelial cell proliferation 0.4086399632939574 0.9523425295279936 0.3409232954668109 1.0 0.4948226854409333 21 Q9NQC3 1 +Negative regulation of epithelial cell proliferation 0.4708618705294305 0.950565594174915 0.3418249411826446 1.0 0.4953236883552284 14 P57105 1 +Positive regulation of monocyte chemotaxis 0.4865822352018176 0.9494506301354312 0.3423914702375021 1.0 0.4953671044786625 4 Q4KMQ2 1 +Negative regulation of ryanodine sensitive calcium release channel activity 0.4510663160969891 0.9493681358826376 0.3424334105797921 1.0 0.4953671044786625 2 P78417 1 +Positive regulation of sequestering of calcium ion 0.4510663160969891 0.9493681358826376 0.3424334105797921 1.0 0.4953671044786625 2 P78417 1 +Negative regulation of calcium ion transport into cytosol 0.4510663160969891 0.9493681358826376 0.3424334105797921 1.0 0.4953671044786625 2 P78417 1 +Nuclear body organization 0.468439509059014 0.9480108563363144 0.3431239274479614 1.0 0.4958851003719929 3 Q15637,O75312 2 +Regulation of exosomal secretion 0.5026027102165267 0.9462592383015296 0.3440163783195664 1.0 0.4968448932898517 9 Q9NQ11,Q92783,O43633,O00560 4 +Mitochondrial fission 0.4594715795042879 0.945234271800698 0.3445392862405776 1.0 0.4974900377302567 15 Q9UDX5,O60313,Q9Y3D6 3 +Phosphatidylinositol 3 kinase signaling 0.4800372356398986 0.9439929763142648 0.3451732374859375 1.0 0.4978548153575343 13 Q05086,O00165 2 +Regulation of extracellular matrix organization 0.5123818778110681 0.9425848984206232 0.3458932672037857 1.0 0.4986729788662353 6 Q14118 1 +Plasma membrane organization 0.3585513707262677 0.9399736554572422 0.3472310740825333 1.0 0.5002702387134799 33 Q96CP7,Q4KMQ2,P16615,Q96GC9,Q9Y3E7,O43633,Q9Y371 7 +Cellular sodium ion homeostasis 0.4976859197803552 0.9365251102986212 0.3490028902162074 1.0 0.5020758686758144 5 P55011,P54709,P05023 3 +Negative regulation of sister chromatid cohesion 0.4487291849255047 0.9354037788182884 0.3495802502227221 1.0 0.5024010562224818 2 Q7Z5K2 1 +Plasma membrane to endosome transport 0.4840689856767159 0.9353002661558516 0.3496335781891444 1.0 0.5024010562224818 4 P61020,Q15286,P51148 3 +Bone remodeling 0.5042881238899134 0.9350880196539472 0.3497429401309886 1.0 0.5024476041318429 8 O14773 1 +Positive regulation of vascular permeability 0.4655172413793088 0.931068862750207 0.3518179440176352 1.0 0.5046511840358433 3 Q16625,Q9UDY2 2 +Positive regulation of blood brain barrier permeability 0.4655172413793088 0.931068862750207 0.3518179440176352 1.0 0.5046511840358433 3 Q16625,Q9UDY2 2 +Regulation of blood brain barrier permeability 0.4655172413793088 0.931068862750207 0.3518179440176352 1.0 0.5046511840358433 3 Q16625,Q9UDY2 2 +Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4478527607362039 0.9301684738206536 0.3522838621345334 1.0 0.5050975295440884 2 P23396 1 +Body morphogenesis 0.5029914064359711 0.9278555901717416 0.3534824834804357 1.0 0.5063895894523265 8 O95470,Q14118 2 +Stress granule disassembly 0.4649327878433685 0.927681364033912 0.3535728781745035 1.0 0.5063895894523265 3 Q07866,P33176 2 +Endosome to lysosome transport via multivesicular body sorting pathway 0.4649327878433407 0.9276813640337512 0.353572878174587 1.0 0.5063895894523265 3 Q9UQN3,Q9Y3E7 2 +Regulation of erad pathway 0.505815507330299 0.9244873568183428 0.3552326311384883 1.0 0.5083206085208356 7 Q4ZIN3,P51572 2 +Maintenance of protein location 0.3580027344875273 0.9242241637668778 0.3553696172657772 1.0 0.5083524955684052 32 P52789,P24390,O15258,O94901,Q96RL7,Q9H4A6,O43292,P30536 8 +Glycerol 3 phosphate metabolic process 0.4463920537540256 0.9214447695419404 0.3568182640558111 1.0 0.5099848825406286 2 P43304 1 +Blastocyst formation 0.4449974655502663 0.9210746337355332 0.3570114627011784 1.0 0.5099848825406286 16 Q9NQC3 1 +Positive regulation of vesicle fusion 0.4637638807714785 0.9209073717478772 0.3570987895362831 1.0 0.5099848825406286 3 P04083,P31751 2 +Positive regulation of sterol transport 0.463763880771476 0.9209073717478626 0.3570987895362907 1.0 0.5099848825406286 3 Q07954,P22307 2 +Positive regulation of low density lipoprotein receptor activity 0.4637638807714607 0.9209073717477724 0.3570987895363378 1.0 0.5099848825406286 3 Q9Y2B0,P61978 2 +Regulation of chaperone mediated autophagy 0.4809648753448544 0.9178301854390566 0.3587077764811006 1.0 0.5121706834795768 4 Q9NQ11 1 +Dttp metabolic process 0.4631794272355229 0.9175209049114792 0.3588697435708505 1.0 0.5122898941680543 3 Q9H773,P04818 2 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.4627725556212375 0.9151636093361496 0.3601057456774803 1.0 0.5135391801181504 3 O95140 1 +Associative learning 0.4849811161014271 0.914532650106616 0.360437029786429 1.0 0.5136286685103271 12 P50897,P05067,O00264,Q9Y639,Q13641 5 +Methionine biosynthetic process 0.5068471247009584 0.912599271485312 0.3614533376236497 1.0 0.5146275655413708 6 Q13126,Q9BV57 2 +Meiotic cell cycle phase transition 0.462302746931622 0.9124419042732428 0.3615361389218667 1.0 0.5146332130139438 3 P30307,O95067 2 +Protein o linked mannosylation 0.4931555104898595 0.9115144864379596 0.3620243562885357 1.0 0.5148916859306688 5 Q8NAT1,O43505,Q6ZXV5 3 +Protein mannosylation 0.4931555104898595 0.9115144864379596 0.3620243562885357 1.0 0.5148916859306688 5 Q8NAT1,O43505,Q6ZXV5 3 +Post embryonic development 0.4542569267106254 0.9114736276341152 0.3620458749439761 1.0 0.5148916859306688 15 O95470,Q96A33 2 +Keratinocyte migration 0.4620105201636441 0.9107490974405742 0.3624275883656671 1.0 0.5148916859306688 3 P58107,Q15555 2 +Regulation of keratinocyte migration 0.4620105201636441 0.9107490974405742 0.3624275883656671 1.0 0.5148916859306688 3 P58107,Q15555 2 +T helper 1 cell differentiation 0.4620105201636266 0.9107490974404732 0.3624275883657204 1.0 0.5148916859306688 3 P04083,P09429 2 +T helper 1 type immune response 0.4620105201636266 0.9107490974404732 0.3624275883657204 1.0 0.5148916859306688 3 P04083,P09429 2 +Positive regulation of cyclase activity 0.4443470639789724 0.9092357611026116 0.3632256912429872 1.0 0.5155767150324463 2 Q16539 1 +Vacuolar acidification 0.4822801494154265 0.8985049851349555 0.3689163886920366 1.0 0.521655484036573 12 Q93050,O75503,Q8N511,P50897,O75787,Q9NWW5 6 +Membrane protein ectodomain proteolysis 0.4903956375105065 0.8984483029318199 0.368946594637999 1.0 0.521655484036573 10 Q9NZ08,Q14118 2 +Positive regulation of smooth muscle cell proliferation 0.4970798819459902 0.8949008598364854 0.3708400870884973 1.0 0.5235389464778786 8 P09601,P35232 2 +Negative regulation of signaling receptor activity 0.4757605387878678 0.888562050798415 0.3742384938157976 1.0 0.5271965661695138 4 P30533,Q9UNH7 2 +Positive regulation of release of cytochrome c from mitochondria 0.5020634094455101 0.8867040162983357 0.3752382754639762 1.0 0.5280352365227069 6 Q96A26 1 +Regulation of receptor recycling 0.5003136250476651 0.8772383008380115 0.3803572166994113 1.0 0.5333296863240895 6 P42892 1 +Positive regulation of leukocyte proliferation 0.4275527027658024 0.8770283228864291 0.3804712544747679 1.0 0.5333296863240895 17 P30825,P14174,P00813,P60033 4 +Bile acid biosynthetic process 0.4902033373925228 0.8760922825712916 0.3809798678770777 1.0 0.5336988363737261 9 Q9BZF3,Q9H4L5,P28288,O14734 4 +Negative regulation of mitochondrion organization 0.4379104594343325 0.8737673882393836 0.3822449437202595 1.0 0.5351265264005691 16 Q9H3K2,Q9H300,O60313,P30536 4 +Midbrain development 0.4130582371198726 0.8731177801079242 0.3825988835675094 1.0 0.5353923926963989 19 O14949,P24539 2 +Peptidyl proline hydroxylation 0.4962850127162226 0.8721554592582877 0.3831235744121217 1.0 0.5356673150058536 7 P13674,O15460,O75718,P07237 4 +Negative regulation of autophagy 0.3823787269420416 0.8716876471075647 0.3833788010370571 1.0 0.5359093818350983 23 O15118,P09601,O75396,Q07820,P30536 5 +Embryonic pattern specification 0.4988627655530942 0.8693925487971126 0.3846324572377924 1.0 0.5369178911682703 6 Q15363 1 +Intra golgi vesicle mediated transport 0.4195876522573166 0.8692594031273093 0.384705262527361 1.0 0.5369178911682703 18 O95249,Q9H9E3,Q9UEU0,Q8TBA6 4 +Recognition of apoptotic cell 0.4376278118609379 0.8691624989020704 0.384758255956674 1.0 0.5369178911682703 2 Q8WTV0 1 +Myeloid cell activation involved in immune response 0.4813206463411476 0.8686168352494187 0.3850567430766318 1.0 0.5370542810962574 11 O95219,P09601,Q12846,Q9NRA0,Q9UNH7,Q99584 6 +Reactive oxygen species metabolic process 0.339588715879871 0.8682554870233026 0.3852544844677841 1.0 0.5370815574357523 41 P52789,P30536,P51790,Q9P0J0,P00374,Q9H300,Q9NRA0,O75027,Q9BSK2,P00403,Q13423 11 +Regulation of mitochondrial dna replication 0.4546412191706844 0.8680979332726316 0.3853407223820142 1.0 0.5370815574357523 3 Q9UJZ1 1 +Unsaturated fatty acid biosynthetic process 0.4922578335212321 0.8680459446606404 0.3853691812238149 1.0 0.5370815574357523 8 O00767,Q9H7Z7,P14174,Q8NCG7 4 +Purine containing compound biosynthetic process 0.3090139420675115 0.8668710190419556 0.3860126841958535 1.0 0.5376034447091984 79 Q8WVC6,Q9UKU0,P24539,P00813,P00846,P50897,Q6Y1H2,P56385,Q13126,P06576,Q8TB61,O75964,P00403 13 +Exocytic process 0.4259632645472088 0.8660757404342315 0.3864486278865016 1.0 0.5380116534107662 17 O95721,O95219,Q9P253,Q12846,P61026,Q9UEU0,Q9UNH7 7 +Cellular response to increased oxygen levels 0.4980815127135815 0.86516895187022 0.3869460638953388 1.0 0.5385893187865185 6 Q15904,Q8N511 2 +Regulation of transport 0.2817374994415924 0.8637448882454433 0.3877280488603076 1.0 0.539217874512162 322 O15260,Q8N183,Q4KMQ2,Q9GZP9,P05556,P49257,Q99623,Q9Y5U9,Q9BRT2,P05067,P50416,Q9H300,P16615,O76024,Q7Z3B4,Q9P2W9,Q9NV70,P14174,Q6IAA8,Q9Y3E7,O43633,P52789,Q9NR31,O75298,P00813,Q92544,P09601,Q15907,O14737,P49755,P18031,P11279,P21796,Q96GC9,Q96KC8,P05023,Q92783,P30536,Q9HD47,Q9Y282,Q08722,O00165,P57105,Q16850,P60033,P51572,Q00765,P05141,O00560,Q15154,Q9NQ11,Q9H4A6,Q9NRA0,O75844,P61026,Q15041,Q8NBM4,Q9Y3D6,Q9P253,P50897,Q8N5M9,P30511,P50402,P27105,P98194,Q96HR9,Q8NBU5,Q9UNH7,Q9Y371 69 +Diol metabolic process 0.4879272028762884 0.8632289822938876 0.3880115817941809 1.0 0.5392618516237367 9 Q13510,P04062,O15269,P00374 4 +Diol biosynthetic process 0.4879272028762884 0.8632289822938876 0.3880115817941809 1.0 0.5392618516237367 9 Q13510,P04062,O15269,P00374 4 +Adult locomotory behavior 0.4254382267421284 0.8624585589629329 0.3884352281746877 1.0 0.5395863605082484 17 P51790,O15118,P50897,P05067,Q8N2K0,O75844 6 +Folic acid metabolic process 0.4943776048359485 0.8616943937095738 0.3888557114820741 1.0 0.5397512406028024 7 P00374 1 +Transepithelial transport 0.4837158499967449 0.8594721427170613 0.3900800827431614 1.0 0.5411744731865906 5 P55011,P78310,P33527 3 +Antigen processing and presentation of exogenous peptide antigen 0.4970108393422875 0.8593820680960473 0.3901297596225637 1.0 0.5411744731865906 6 P04439,P30511,Q03518 3 +Organelle transport along microtubule 0.3528852298732037 0.8590770404295774 0.3902980133992444 1.0 0.541177874144067 30 P62820,O94901,O60313,Q5SNT2,O75381,P11279,P07196 7 +Negative regulation of neuron apoptotic process 0.3558221751608105 0.858783109273546 0.390460188040405 1.0 0.5412877697022221 26 P04062,P09601,P50897,O76024,Q01105,P07196 6 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.4903518020134694 0.8574390549150671 0.3912022830486787 1.0 0.5417417322763528 8 P60468,Q9UGP8,P46379,O43681 4 +Peptidyl glutamine methylation 0.4355828220858893 0.8569816776955775 0.3914550106704488 1.0 0.5418829889346514 2 Q9UI30 1 +Positive regulation of bone mineralization 0.4526019154388718 0.8563101306954624 0.3918262591319508 1.0 0.5420304767140018 3 Q4KMQ2 1 +Positive regulation of biomineralization 0.4526019154388718 0.8563101306954624 0.3918262591319508 1.0 0.5420304767140018 3 Q4KMQ2 1 +Positive regulation of exosomal secretion 0.4897682050869045 0.854192428565906 0.3929983776623633 1.0 0.5433827556414288 8 Q9NQ11,Q92783,O43633 3 +Lysosomal transport 0.3288251974332808 0.8540928973663793 0.3930535190163644 1.0 0.5433827556414288 46 Q9NZJ7,Q9P253,Q96ED9,Q9UNK0,O15118,P07602,Q9NQ11,P11279,Q14108,P13473,Q9Y3E7,O43633 12 +Cellular metabolic compound salvage 0.4785190046001385 0.8522847188519759 0.3940560853358277 1.0 0.5442143713724302 11 P00813 1 +Cytosolic transport 0.3050155950560728 0.8514105982619156 0.3945413064841632 1.0 0.5447473876329563 70 O15260,O43752,O95249,P49257,Q96RL7,Q96ED9,O60499,O75503,Q9UNK0,Q9UBQ0,Q13190,Q9UEU0,P11279,O60749,P20340,Q9Y3E7,Q9UNH7,Q9UID3 18 +Adenylate cyclase inhibiting g protein coupled receptor signaling pathway 0.4952871242654455 0.8500690691474722 0.3952866870144218 1.0 0.5454304571613074 6 P07602 1 +Regulation of cellular response to osmotic stress 0.4683648373219659 0.8470334620946757 0.3969764703832206 1.0 0.5468896559803942 4 O95202 1 +Cell cell recognition 0.4641404974084716 0.8470329113984897 0.3969767773253752 1.0 0.5468896559803942 13 P45880 1 +Detection of biotic stimulus 0.4806400681808158 0.8425420883671343 0.3994845912691456 1.0 0.5495965040684894 5 Q8WTV0,P30536 2 +Snorna localization 0.467515082900428 0.842267716562095 0.3996381172448981 1.0 0.5496918730245881 4 Q8WWY3 1 +Carnitine metabolic process 0.4804374497301622 0.8414273740133517 0.4001085554440018 1.0 0.5502230145225288 5 P50416,P23786 2 +Dna deamination 0.4671148786904452 0.8400236859279524 0.4008951062464034 1.0 0.5510724896981515 4 Q5RKV6,Q9NQT5,Q9NQT4 3 +Locomotory behavior 0.3477466709647335 0.8390668219269681 0.4014318129615479 1.0 0.5515941210677721 33 P54802,Q05086,Q96RL7,P51790,O15118,P50897,P05067,Q8N2K0,O75844,Q9NWW5 10 +Clathrin dependent endocytosis 0.43168412046487 0.8322581824406046 0.4052632290638061 1.0 0.5557895712875055 16 Q5VW38,Q9NUN5 2 +Extracellular vesicle biogenesis 0.4787876817443605 0.8318390252623753 0.4054998127935234 1.0 0.5558804657530704 10 Q9NQ11,Q92783,O43633,O00560 4 +Positive regulation of dna damage response signal transduction by p53 class mediator 0.4479836353009807 0.8296446144331465 0.4067397443666449 1.0 0.5572291817891832 3 O43324,P17844 2 +Multicellular organismal signaling 0.3517345584281449 0.8282403004090583 0.4075344247865122 1.0 0.5581302276683858 27 P78310,Q9HD47,P04062,P16615,O75844,P05023,Q6PI78 7 +Positive regulation of torc1 signaling 0.4649196625595081 0.827720191550967 0.4078289813739393 1.0 0.5583698805388163 4 Q9NWS0 1 +Regulation of neurotransmitter levels 0.3505306180630378 0.8235325455853607 0.4102052173628805 1.0 0.5603306168657679 28 O95721,P05556,P20339,Q9P253,P50897,Q12846,P16615,P21964,Q8NCG7 9 +Regulation of receptor signaling pathway via stat 0.4870665515128134 0.8216488113844459 0.4112768003380551 1.0 0.5614247756180567 7 Q9NX40 1 +Positive regulation of activated t cell proliferation 0.4465225014611256 0.8212176645075012 0.4115222964663605 1.0 0.5614247756180567 3 P23396,P09429 2 +Maintenance of presynaptic active zone structure 0.4291557113643026 0.8187575477276854 0.4129247560602407 1.0 0.5629851310696014 2 Q8IUD2 1 +Cell cell signaling involved in cardiac conduction 0.4755683952387199 0.814663155526223 0.4152651489041123 1.0 0.565585414572511 5 Q9HD47,P78310 2 +Negative regulation of protein secretion 0.4792498352030284 0.8142624133717257 0.4154946372036341 1.0 0.5657799315113315 9 Q16850 1 +Positive regulation of nervous system process 0.4753313825046258 0.813361550351797 0.4160107972474987 1.0 0.5663646474310056 5 P04062,Q14118 2 +Cellular hyperosmotic salinity response 0.4622192485281571 0.8125989701627613 0.4164480222123112 1.0 0.5666053957903227 4 O95202,Q9BPX6 2 +Cellular response to salt stress 0.4622192485281571 0.8125989701627613 0.4164480222123112 1.0 0.5666053957903227 4 O95202,Q9BPX6 2 +Hyperosmotic salinity response 0.4622192485281571 0.8125989701627613 0.4164480222123112 1.0 0.5666053957903227 4 O95202,Q9BPX6 2 +Cd4 positive alpha beta t cell differentiation 0.462145571470343 0.8121866338700348 0.416684547913102 1.0 0.5666895917335998 4 P40763,P04083,P09429 3 +T cell differentiation involved in immune response 0.462145571470343 0.8121866338700348 0.416684547913102 1.0 0.5666895917335998 4 P40763,P04083,P09429 3 +Regulation of mitochondrial gene expression 0.458267713399013 0.8112981174151459 0.4171944909163851 1.0 0.5670301138251431 13 Q9BRT2,Q9Y2R0,Q6P087,Q567V2 4 +Cytokine production involved in immune response 0.4579841116888 0.8095741344578047 0.4181849789782048 1.0 0.5674312082248434 13 P60033,P30511,P14174,P09601 4 +Regulation of leukocyte differentiation 0.3662626489921788 0.8058429279662552 0.4203334223086572 1.0 0.569517762729538 24 P00813,O96005 2 +Actin mediated cell contraction 0.410312725924296 0.8039073933866437 0.4214504598594972 1.0 0.5707943157599166 18 Q9HD47,Q9UM22,P60660,P16615,P05023,P09493 6 +Dna integration 0.4265264387963727 0.8031499211133524 0.4218880866283356 1.0 0.570934246708633 2 O75531 1 +Homeostatic process 0.2791462812539542 0.8021944026854582 0.4224405136756977 1.0 0.5713055051325782 318 O15260,Q8N183,O00767,Q05086,P04062,Q4KMQ2,Q96A33,P51790,P05067,O75787,O14773,Q9NWR8,Q9NQC3,P16615,Q16891,O76024,O43819,Q92542,P23786,Q9Y639,P14174,Q6IAA8,P52789,Q96ER9,P49069,O95202,P00813,Q92544,P09601,Q15907,P30519,Q96AQ8,Q9NWW5,P05023,P30536,Q9HD47,P35670,P51572,P05141,Q8N511,Q9P0S9,Q96H78,Q9BWH2,Q9NQ11,O75027,Q8IYU8,Q9NX40,Q9P035,P13473,Q9HD20,Q8NF37,Q9Y6C9,Q8NE01,Q6IAN0,Q9UM00,O75880,P78310,Q93050,Q96CP7,Q9Y3D6,Q8WWC4,O15118,O95140,P50897,Q8N5M9,P06576,Q07820,P98194,Q8NEW0 69 +Negative regulation of intrinsic apoptotic signaling pathway 0.3402428762704068 0.8014563226069601 0.4228675200790779 1.0 0.5715277786907289 36 Q9P0J0,O60313,Q8N2F6,P45880,Q9H300,O76024,Q07820,P14174 8 +Regulation of macrophage migration 0.4857606229777231 0.7986905793949415 0.4244698506252191 1.0 0.5731001416507613 6 P60033 1 +Regulation of collagen metabolic process 0.459564026220053 0.7977469504840033 0.4250173520267619 1.0 0.5737206935547357 4 P08670 1 +Regulation of intrinsic apoptotic signaling pathway 0.3024960373169144 0.7963251647045466 0.4258430626109124 1.0 0.5745976669541208 55 Q9Y3D6,P51572,Q9P0J0,O60313,O60443,Q8N2F6,P45880,Q9H300,O76024,Q07820,P14174 11 +Carbohydrate derivative metabolic process 0.2911582161311389 0.7954306969277769 0.4263630095017321 1.0 0.5750615136420056 278 O75746,Q9Y2B2,P04062,Q86YN1,P54802,Q7LGA3,P05067,P56385,Q53GQ0,Q9BRR6,Q9BT22,Q9NZD2,O60725,Q92542,Q9NUJ1,P52789,P53007,P62820,Q8NBI6,Q2TAA5,Q4G148,P00813,Q9UJS0,P00846,Q6Y1H2,P46977,Q8WVQ1,Q9H490,P49915,Q86UL3,Q9NPH0,Q9NX62,Q8TB61,Q10472,Q9HCC0,Q96AA3,Q6ZXV5,Q9NWW5,Q99805,Q9UKU0,Q9BYC5,O60313,Q9NQX7,Q8NCH0,P17900,Q9H4A6,Q9NRA0,Q13126,Q8NBX0,O43292,Q9BXS4,Q8IWA4,O60476,O75964,P00403,Q8WVC6,Q9Y673,Q9Y2C2,Q8NAT1,P24539,Q9H0U4,Q96L58,Q9UMR5,O15118,Q9BW91,P50897,Q96S52,Q9P2E5,Q92643,P06576,Q9UKV5,Q9H0U3 72 +Positive regulation of dna dependent dna replication 0.4716374269005728 0.7930914112056142 0.4277245664883482 1.0 0.5761919502781102 5 P24941,Q9UJZ1,Q04837,Q9ULV3 4 +Calcium ion regulated exocytosis 0.4787359728991522 0.7929293392195644 0.4278189924935662 1.0 0.5761919502781102 8 P16615 1 +Isotype switching to iga isotypes 0.4412624196376224 0.7909240091981171 0.428988336955284 1.0 0.577171447577101 3 P43246,O96028 2 +Potassium ion import across plasma membrane 0.4840972831856962 0.7897384005949392 0.4296805601432365 1.0 0.577864585211176 6 P55011,P54709,P05023,Q9BXP2 4 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.4780502843644103 0.7891297245723429 0.4300361904458691 1.0 0.5782237386674838 8 O95881,P18031,O60313,O76024 4 +Anatomical structure maturation 0.3421928803030035 0.7872433798007417 0.4311394075416408 1.0 0.5792298934825748 33 P04062,Q96KR6,Q9NZJ7,Q15125,O75503,P05067,O75787,Q86UL3,Q9Y2W6,Q14118,Q15645,P09622 12 +Regulation of mitochondrial membrane permeability 0.4346234469659253 0.7846575383369118 0.4326543848361206 1.0 0.5806290501479827 15 P45880,P05141,P12235 3 +Regulation of fatty acid biosynthetic process 0.4791345914252209 0.7783173672929901 0.4363819394625221 1.0 0.5844905000164179 7 Q92604,O75477 2 +Reproductive system development 0.295335039139176 0.7782899740529027 0.4363980847242679 1.0 0.5844905000164179 62 O95470,Q05086,Q9NZJ7,P00813,Q96DA6,P07602,P35613,Q15392 8 +Acute inflammatory response 0.4686696672875182 0.7768296371255073 0.4372592887558679 1.0 0.5850483424323385 5 Q9BQE5 1 +Negative regulation of growth 0.3445514045342978 0.7764852529075927 0.4374625248235884 1.0 0.5851957709115543 29 P35232,Q9P0J0,P50897,O14681,Q9NQC3 5 +Antigen processing and presentation of peptide antigen 0.4429260185305632 0.7754041455096764 0.4381008863017506 1.0 0.5856896550845438 14 P30511,P10321,Q9NZ08,Q03519 4 +Cohesin loading 0.4380479251899348 0.7724485534179274 0.439848806292727 1.0 0.5870646099936458 3 Q7Z5K2,Q9Y6X3 2 +Mast cell activation 0.4713717322085206 0.7699345187911941 0.4413387364306893 1.0 0.5884516485742525 9 O95219,P09601,Q9NRA0,Q9UNH7,Q99584 5 +Morphogenesis of a branching structure 0.4053608759758276 0.7690978267525672 0.4418352382428903 1.0 0.5888730982543053 18 Q15363,Q99623,Q9NQC3 3 +Negative regulation of bmp signaling pathway 0.4671803447160438 0.7686774817407217 0.4420847959957419 1.0 0.5889652139306537 5 Q9Y2U8 1 +Collagen fibril organization 0.4769928259873942 0.7666420294289285 0.4432943792553281 1.0 0.5903357217010978 7 P13674,Q92791 2 +Amyloid beta clearance by cellular catabolic process 0.4200993280748005 0.7650843557097257 0.44422131493004 1.0 0.5910877994014067 2 Q07954 1 +Ovarian follicle development 0.4794703083273747 0.7648700934081805 0.4443489039787569 1.0 0.5911370786984563 6 Q05086 1 +Sprouting angiogenesis 0.4307930805482084 0.760010999212063 0.4472480101807374 1.0 0.5945092670453785 15 P09601 1 +Intracellular lipid transport 0.4496625631910367 0.7590725297150516 0.4478091707809781 1.0 0.5951340119825378 13 P50416,P28288,P23786,O15118 4 +Multivesicular body sorting pathway 0.46588579795024 0.7580897592375812 0.4483972499352129 1.0 0.595430685023814 10 Q9NZZ3,Q8WUX9,Q9UQN3,Q99523,Q9HD42,Q9BRG1,Q9Y3E7,Q92783,O43633 9 +Endosome transport via multivesicular body sorting pathway 0.46588579795024 0.7580897592375812 0.4483972499352129 1.0 0.595430685023814 10 Q9NZZ3,Q8WUX9,Q9UQN3,Q99523,Q9HD42,Q9BRG1,Q9Y3E7,Q92783,O43633 9 +Positive regulation of adaptive immune response 0.3894953214615165 0.7528770959646798 0.4515237727544896 1.0 0.5983652433092383 20 P60033,P30511,O15400,P00813 4 +Response to zinc ion 0.4641504279883356 0.7521115038564536 0.4519840064219227 1.0 0.5987320604550145 5 P30536 1 +Spermine metabolic process 0.4177621969032961 0.751276641846829 0.4524861836485125 1.0 0.599275675970276 2 Q96QD8 1 +Regulation of atp biosynthetic process 0.4736663704290324 0.7485326208286148 0.4541389565133134 1.0 0.6001253255301436 7 Q9NRA0,P00403 2 +Regulation of b cell proliferation 0.4705916300413457 0.7478743744059738 0.4545359356656075 1.0 0.6002853708325079 8 P60033,P00813 2 +Neuron death 0.2997665727507563 0.7448128306921586 0.4563848772488783 1.0 0.6022017504873763 78 P04062,Q9NR28,Q96A26,P50897,P09601,Q4ZIN3,P30511,Q9NQ11,O76024,Q07820,Q15392,Q01105,Q92542,P07196 14 +Long term synaptic potentiation 0.4596463266952665 0.7426574209504687 0.4576891145586939 1.0 0.6033510783196999 11 Q9BPZ3,Q92542,Q9Y639,P05067 4 +Response to testosterone 0.4662843271073577 0.7413920697986518 0.4584557513993574 1.0 0.6039865361336538 9 Q13126,P30536 2 +Negative regulation of fatty acid biosynthetic process 0.448789553087302 0.7376752646318887 0.4607118066801281 1.0 0.6057879261851339 4 O75477 1 +Regulation of leukocyte mediated cytotoxicity 0.4584794438898432 0.7359087550338658 0.4617862288237093 1.0 0.606913730976681 11 P30511,P11279 2 +Nucleoside catabolic process 0.4603118210516853 0.731163539065695 0.4646792678632248 1.0 0.6103473361390607 5 P00813 1 +Myeloid leukocyte mediated immunity 0.4059226939151013 0.7284428960615383 0.4663425126511753 1.0 0.6117155108922192 17 O95219,P09601,Q12846,Q8N5M9,Q9NRA0,Q9UNH7,Q99584 7 +Intermediate filament organization 0.4722267875205761 0.7260543341319463 0.4678054623555541 1.0 0.6131412610019673 6 P08670 1 +Ribonucleoprotein complex disassembly 0.459356725146204 0.7259587628094385 0.467864050870943 1.0 0.6131412610019673 5 Q07866,P55072,Q14562,P33176 4 +Regulation of immune effector process 0.3107726180751226 0.7256367212422333 0.468061503379428 1.0 0.6131412610019673 49 O15400,P35232,Q08722,P60033,Q99623,P09601,P30511,P11279,P14174,Q96FZ2 10 +Amyloid beta clearance by transcytosis 0.4711927940140744 0.7205263882108455 0.4712009584338923 1.0 0.6161858687212438 6 P30533,Q15907 2 +T cell mediated cytotoxicity 0.4624510394905875 0.7199365606299349 0.4715640562306196 1.0 0.6164196644778404 9 P53634,P30511,O15400 3 +Organ growth 0.3478794721179901 0.718961412906444 0.4721646952836256 1.0 0.6164416124107995 25 Q05086,Q9NZJ7,Q9Y5U9,P07602,O75844 5 +Pore complex assembly 0.4338029610070266 0.7185610577062557 0.4724114147533267 1.0 0.6164416124107995 14 Q5EBL8,Q9BTX1,Q4KMQ2,Q9NQC3 4 +Ganglioside metabolic process 0.4453191243779522 0.7184049288416403 0.4725076486317783 1.0 0.6164416124107995 4 Q9NWW5 1 +Regulation of response to osmotic stress 0.4579689143662102 0.7184014212613039 0.4725098107394574 1.0 0.6164416124107995 5 O95202,Q9BPX6 2 +Inorganic ion import across plasma membrane 0.4649916186103059 0.7170035431978453 0.4733719103989424 1.0 0.617293613880203 8 P54709,Q15043,P55011,P05023,Q9BXP2 5 +Regulation of biomineralization 0.4671399044812201 0.7130970492607513 0.4757857052932437 1.0 0.6198222079733177 7 O75844 1 +Negative regulation of blood pressure 0.444125869733123 0.7117892398590543 0.4765952967930198 1.0 0.6205054043607565 4 Q9HB40,P42785 2 +Signal release 0.3000122689003878 0.7064428640697371 0.4799127725396781 1.0 0.624093942289001 53 Q8N183,O95721,P62820,P20339,Q9BRT2,Q9P253,P50897,Q15907,Q12846,P50416,Q8N5M9,P16615,P14174,Q9UNH7,Q96TA1 15 +Neuron projection guidance 0.3373612606790997 0.7064229026526311 0.4799251823362109 1.0 0.624093942289001 28 P35613,O00264,P42892,Q14118,Q9Y639 5 +Glycosylceramide catabolic process 0.426104117958775 0.7041062768508064 0.4813665914630864 1.0 0.6254699659775136 3 P04062 1 +Regulation of multicellular organism growth 0.4122468375695352 0.7032802737044626 0.4818811015203947 1.0 0.6259557523852022 16 O95470,P11802,O43464,P05067,Q86UL3,O75844 6 +Methionine metabolic process 0.4651216671467769 0.7021672070557258 0.4825748937433491 1.0 0.6266657860267721 7 Q13126,Q9BV57 2 +Protein localization to phagophore assembly site 0.4647347922397051 0.7000737098924962 0.4838812732260127 1.0 0.6277977497650643 7 P56962 1 +Positive regulation of immune effector process 0.3229349239352862 0.6995938815675455 0.4841809646489881 1.0 0.6280018552013896 41 O15400,P35232,P60033,Q99623,P09601,P30511,P11279,P14174,Q96FZ2 9 +Regulation of muscle contraction 0.3680881732872789 0.6988732170825606 0.4846312666811756 1.0 0.6283208155654505 22 Q9HD47,P00813,P16615,P09493 4 +Positive regulation of protein localization to cell periphery 0.3952787624812313 0.6984822325677821 0.48487566548124 1.0 0.6284034830775332 18 Q9HD47,P05556,O15258,O00264,P98194 5 +Negative regulation of hematopoietic progenitor cell differentiation 0.4084136722173508 0.6962640212725881 0.4862635005815243 1.0 0.6292028011488981 2 Q92785 1 +Lipopolysaccharide mediated signaling pathway 0.4580504096839281 0.6953663734315965 0.4868257283601003 1.0 0.6296446869035927 9 P14174,Q86UE4,Q16539 3 +Regulation of adaptive immune response 0.3450437893591507 0.6950157479482314 0.4870454325376792 1.0 0.6296446869035927 25 P60033,P30511,O15400,P00813 4 +Protoporphyrinogen ix metabolic process 0.4535973721157825 0.6946412231911552 0.4872801712985524 1.0 0.6296446869035927 5 P22830 1 +Positive regulation of blood vessel endothelial cell migration 0.4466264286759078 0.6881474511701683 0.4913599315812347 1.0 0.6335369609643097 12 P09601 1 +Positive regulation of amyloid beta clearance 0.422267679719452 0.6822754327471674 0.4950648044837868 1.0 0.6364283268354 3 P30533,Q07954 2 +Activation of phospholipase d activity 0.4216832261835207 0.6789555775367484 0.4971660091663161 1.0 0.6384318114787574 3 P40616,P18085 2 +Establishment of sister chromatid cohesion 0.4381759719380242 0.6788860443869456 0.4972100688661156 1.0 0.6384318114787574 4 Q9GZZ1,Q7Z5K2,Q9Y6X3 3 +Positive regulation of secretion 0.3103207685523158 0.6759244436791959 0.4990886173941358 1.0 0.6398370962979023 47 O95219,O00560,P20339,Q9Y5U9,Q12846,P49755,Q9NQ11,Q9H4A6,P11279,Q9NRA0,P30511,Q9NV70,P55011,P14174,Q92783,O43633 16 +Specification of symmetry 0.4512933731835646 0.6752463384213134 0.4995192706907354 1.0 0.6402634594677246 10 O75665,Q9Y673,Q15363 3 +Circulatory system process 0.29474561756288 0.6691885141283211 0.5033752321558385 1.0 0.6444466592495222 80 P30825,P78310,Q9HD47,P00813,P09601,Q9NZ08,Q9HB40,O75787,P16615,P00387,P42892,Q6RW13,O75844,P05023,P09493,Q6PI78 16 +Sulfur amino acid biosynthetic process 0.4588582890478214 0.6683434449912625 0.5039143871596512 1.0 0.6448839677275442 7 Q13126,Q9BV57 2 +Adult behavior 0.3640866489570312 0.6679378922777535 0.5041732383982778 1.0 0.6450887691618888 22 O75844,P51790,O15118,P50897,P05067,Q8N2K0,Q92542 7 +Negative regulation of cellular response to growth factor stimulus 0.4461587238482078 0.6649418405570031 0.5060876928883207 1.0 0.6465245516976432 11 P18031,Q9Y2U8,Q96TA1 3 +Cytokine production involved in inflammatory response 0.460665006653799 0.6644570647320298 0.5063978200859478 1.0 0.6467941634750669 6 Q8IV08,Q16539 2 +Regulation of alpha beta t cell activation 0.445972145885198 0.6638717534547309 0.5067723962890696 1.0 0.6468928828656718 11 P00813 1 +Cerebellar cortex development 0.4334493242262414 0.6613054803206104 0.5084164276293326 1.0 0.647992766203755 13 O14949 1 +Regulation of vesicle mediated transport 0.2874953466794873 0.6592991236571258 0.5097037050479072 1.0 0.6489798237570924 119 Q4KMQ2,P05067,P16615,Q9P2W9,Q9Y3E7,Q9HCU5,O43633,Q9NR31,P09601,Q15907,P18031,P11279,Q92783,Q08722,O00560,P57105,Q9NQ11,Q9NRA0,P61026,Q9P253,P50897,P30511,P98194,Q8NBU5 24 +Cellular response to mineralocorticoid stimulus 0.4181765049678499 0.6590714053632721 0.5098499167157322 1.0 0.6489798237570924 3 P20020,O95831 2 +Negative regulation of establishment of protein localization to mitochondrion 0.4345741175683533 0.6590420754924351 0.5098687502163721 1.0 0.6489798237570924 4 P49257 1 +Regulation of body fluid levels 0.295966899521323 0.6589540854883847 0.5099252531539775 1.0 0.6489798237570924 53 P04062,Q4KMQ2,P35670,P49257,P00813,Q13505,Q86UL3,Q9BWH2,O76024,P61225,P00403 11 +Negative regulation of cell projection organization 0.330021304216435 0.6586861226383994 0.5100973461546632 1.0 0.6489798237570924 31 Q05086,Q9NQX7,Q96G23,P08670,Q9NQC3 5 +Regulation of systemic arterial blood pressure 0.4541407634963321 0.6575007662247726 0.5108589784618311 1.0 0.6496955798556077 8 O75787,P09493 2 +Gdp metabolic process 0.4340836012861875 0.6563443220727395 0.5116026059274488 1.0 0.6504484851814376 4 O14936,Q9UDY2,Q00013 3 +Protein targeting to lysosome 0.4442684318173745 0.6541075092813246 0.5130425438736748 1.0 0.6518376267822789 11 P13473 1 +Negative regulation of apoptotic signaling pathway 0.2884756503495767 0.6534402432086763 0.5134725018059538 1.0 0.6520032078952085 67 P61289,P05141,Q9H3K2,Q9P0J0,O60313,P09601,Q8N2F6,P45880,Q8IWB1,Q9H300,O76024,Q07820,P14174 13 +Regulation of membrane permeability 0.3822466809183497 0.6516846956330852 0.5146045974897304 1.0 0.6533121148315679 19 P45880,P05141,P12235 3 +Myeloid leukocyte differentiation 0.3298523443856736 0.6506918937002223 0.5152453970483224 1.0 0.6533647925274765 30 P04062,Q9BRX8,O00165,P60033,P05067,Q8N5M9,Q14739,Q15904,Q6IAN0,Q13619 10 +Regulation of aerobic respiration 0.4225963235662929 0.6491653563966531 0.5162315014486087 1.0 0.6543610177585472 14 O14548,Q9BSK2,P14406 3 +Negative regulation of transport 0.2919888773626883 0.6480351169741592 0.5169622374523892 1.0 0.6550328971446423 76 Q8N183,Q9GZP9,Q08722,Q9Y3D6,P49257,Q16850,P00813,P09601,Q8N5M9,P30511,P21796,Q8NBM4 12 +Protein maturation 0.2933010432270441 0.6459621964028591 0.5183038381201757 1.0 0.6559833648192742 81 Q96TA2,Q9Y366,O75787,Q9H300,O76024,Q9BU89,Q9UJZ1,Q99797,Q92542,Q10713,P49366,P67812,P42892,P35670,Q2T9J0,Q5JRX3,Q6NXT4,Q12797,Q9UG56,Q96F07,Q9Y4W6,Q9BXS4,O75844,O75503,O43464,Q92896,Q10471,Q15392,Q15005 29 +Glycosyl compound metabolic process 0.3298226493228942 0.6397702632669531 0.5223219678502506 1.0 0.6595198851308387 28 P00813,Q13126,Q9NUJ1 3 +Protein quality control for misfolded or incompletely synthesized proteins 0.4381353489210113 0.6386357116148785 0.5230599437867758 1.0 0.6601963095591787 12 Q16740,Q9Y679,Q9BUN8,P46379 4 +Ketone biosynthetic process 0.4476583988111091 0.6376465764931066 0.5237037691474531 1.0 0.6608811531015993 9 Q96D53,Q8NI60,Q9Y5Z9 3 +Lens development in camera type eye 0.454856282042294 0.6337116952115026 0.5262689910653693 1.0 0.6626661016215307 6 Q99797,P08670 2 +Regulation of skeletal muscle fiber development 0.3976044405492308 0.6331861579782293 0.5266120838466717 1.0 0.6627913024273686 2 Q96TA1 1 +Nerve development 0.446844303613455 0.6331451487977645 0.5266388611658641 1.0 0.6627913024273686 9 Q9H061,Q14118 2 +I kappab kinase nf kappab signaling 0.2935309319409242 0.6303933892033483 0.5284372349669784 1.0 0.6645421440694346 53 Q96HY6,Q86UE4,O43657,P09601,Q8WVQ1,Q8TB61,Q99584,Q9P035 8 +Exocrine system development 0.4540772002722688 0.6295997022457305 0.5289565184433447 1.0 0.6648603103793281 6 Q14118 1 +Organelle localization 0.2889668149324899 0.6293840958439634 0.529097627515412 1.0 0.6648603103793281 182 O15400,Q8N6H7,P05556,Q96A57,P16615,Q9Y3E7,Q6IAA8,Q9HCU5,O43633,Q13561,Q99584,Q15363,P62820,P07196,Q9NR31,O95721,P09601,Q96DB5,Q5SNT2,Q15907,Q12846,P49755,P11279,Q96GC9,P20340,Q9BZG1,Q92783,P56962,O00560,O60499,O60313,Q13190,Q15154,Q8IWA4,Q9NRA0,Q9NQ11,P61026,O94901,O43752,Q9P253,Q9UNK0,O95140,O75381,Q9UEU0,Q9UNH7,Q9UH99 46 +Protein trimerization 0.4285061834752101 0.6257542719096568 0.5314761296122348 1.0 0.6673882276632054 4 P14174 1 +Synaptonemal complex organization 0.4508948796671252 0.6255762029294171 0.5315929515827642 1.0 0.6673882276632054 7 Q92791,Q15645 2 +Sulfur compound biosynthetic process 0.2997139118183413 0.6255341770944779 0.5316205244866219 1.0 0.6673882276632054 50 P53007,Q9Y2C2,Q9UKU0,O43505,Q99735,Q9UHY7,Q96L58,Q9UMR5,Q6Y1H2,P50897,Q8NCH0,Q9P2E5,Q53GQ0,Q9UJ14,Q9BV57,Q13126,Q8TB61,P09622 18 +Negative regulation of establishment of protein localization 0.3285377203676188 0.6243138701933676 0.5324214766757067 1.0 0.6682652181770838 27 Q9GZP9,P49257,Q16850,Q8N5M9,Q8NBM4 5 +Positive regulation of vasculature development 0.3649433052889513 0.6216425338738937 0.5341769462532913 1.0 0.6699533343211307 21 P52789,Q86UE4,P05556,Q9H2J4,Q9NZ08,P09601 6 +Extracellular exosome assembly 0.427635305282028 0.6209926042190856 0.5346044893137003 1.0 0.6703607580176404 4 Q92783 1 +Mitochondrial outer membrane permeabilization 0.4434654866186989 0.6144974465742352 0.5388866598842932 1.0 0.6744348381373976 9 P45880 1 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.446152169355373 0.6140151976375072 0.5392052845054387 1.0 0.6745749515621893 8 Q8N183,Q8N5M9 2 +Skeletal system morphogenesis 0.3886942581398869 0.6113528388732844 0.5409660173178765 1.0 0.6758710356078657 17 O95470,P16435,Q16539,Q92896,Q9NX62,O75844,Q93063 7 +Protein targeting to vacuole 0.4073809562327011 0.6105927801252369 0.5414692036160607 1.0 0.6762408573188529 15 P13473,Q14108 2 +Inositol phosphate catabolic process 0.4375874814270099 0.6083186055774408 0.5429761834554181 1.0 0.6775129355013285 5 Q9NX62 1 +Regulation of production of molecular mediator of immune response 0.324905595937175 0.6063105927790353 0.5443085258680802 1.0 0.6786454528817346 30 P35232,P60033,Q99623,P09601,P30511,Q9NRA0,P14174,Q96FZ2 8 +Purine nucleoside metabolic process 0.4384296873117216 0.6029380984944624 0.5465498698131044 1.0 0.6807627456859274 10 P00813,Q13126 2 +Regulation of vacuole organization 0.4304075261242758 0.593880752004054 0.5525918737129263 1.0 0.6865170027586668 12 O95219,Q9H0U4,P20339,Q5VWJ9,O75396,Q14108,Q9Y371 7 +Immature b cell differentiation 0.3897166228454667 0.5876031389475009 0.556798703637345 1.0 0.6906730182886899 2 Q7Z5L9 1 +Second messenger mediated signaling 0.3322391858928414 0.5875506249546566 0.5568339606699411 1.0 0.6906730182886899 25 Q9Y3D6,O75844,P00813,P16615 4 +Positive regulation of intracellular signal transduction 0.2793720162756166 0.5866197466366319 0.5574591175863277 1.0 0.6911018528269043 146 Q86UE4,O43657,Q05086,Q99623,Q7Z7H5,P05067,O60443,Q9NQC3,P14174,Q6IAA8,Q99584,Q9Y639,P00813,P09601,Q8WVQ1,P18031,Q8TB61,O00560,O00165,P60033,P51572,Q9H4A6,Q9NRA0,Q13641,Q9Y3D6,P35232,Q9Y3E0,Q96AG4,Q07820,P98194,Q9NWS0 31 +Fatty acid derivative biosynthetic process 0.3943546306095256 0.5859741388301054 0.5578928938120549 1.0 0.6913363166507248 16 Q9UKU0,Q6Y1H2,P50897,Q53GQ0,Q9UJ14 5 +Regulation of protein localization to cell surface 0.4290337387754842 0.5859594715728426 0.5579027504754306 1.0 0.6913363166507248 12 Q9HD47,Q92544,Q15907 3 +Nucleobase containing small molecule catabolic process 0.445567435464633 0.5848840051253789 0.5586257142097377 1.0 0.6917125687331502 6 P00813 1 +Memory 0.4374477244805462 0.5814355600795024 0.5609469369091289 1.0 0.6939286723787745 9 Q9BPZ3,O00264 2 +Epithelial cell proliferation 0.3063748104860747 0.5777990703123629 0.5633997830294875 1.0 0.6960397016685265 44 P57105,Q9NQC3,P09601 3 +Synaptic vesicle membrane organization 0.4437357567560672 0.5753104004063753 0.5650813888578503 1.0 0.6978530659220672 6 O95721,O43760 2 +Regulation of cell killing 0.4268986327401921 0.5736710640432361 0.5661904127754449 1.0 0.6986364396379977 12 P30511,P11279 2 +Receptor clustering 0.4181967042957955 0.570438389792973 0.5683803979738045 1.0 0.7007341337059482 13 P60033,P57105,O43805 3 +Regulation of neuronal synaptic plasticity 0.4379382973564811 0.5696480823668177 0.5689164096801784 1.0 0.7011301344897498 8 Q9Y639,Q96A49,P05067 3 +Carbohydrate transmembrane transport 0.3917684789966644 0.5691827612256636 0.5692321182287423 1.0 0.7013868002637278 16 P52789,P31751,O75298,Q16539,P11166,Q9BZF1,Q6ZWJ1 7 +Intracellular distribution of mitochondria 0.4009334253877099 0.5623217962382222 0.5738967905687711 1.0 0.7055633119741629 3 O75153 1 +Positive regulation of hemopoiesis 0.4167967199985334 0.5621676715313185 0.5740017854014212 1.0 0.7055633119741629 13 P00813 1 +Muscle adaptation 0.3755930953461114 0.5621309989906448 0.5740267692853522 1.0 0.7055633119741629 18 P16615,P09601 2 +Protein hexamerization 0.4402362214167211 0.5570743682988631 0.5774766191898062 1.0 0.7086013781264249 6 O95202 1 +Positive regulation of leukocyte cell cell adhesion 0.3356621031109238 0.5558617479779513 0.5783053696583191 1.0 0.7090866741415303 24 P00813,Q08722 2 +Somatic stem cell population maintenance 0.3988895382816945 0.55098555644856 0.5816435758071745 1.0 0.7121097642290389 3 Q9Y6J9,Q13619 2 +Myeloid leukocyte cytokine production 0.4361906492397438 0.5474633963547847 0.5840604111820071 1.0 0.7146666099711607 7 P09601 1 +Neurotransmitter secretion 0.3673725188512942 0.5465148428804647 0.5847120876591998 1.0 0.7149279843115296 19 O95721,P20339,Q9P253,P50897,Q12846,P16615 6 +Alpha beta t cell activation 0.3970962812278239 0.5459133744999375 0.5851254843642479 1.0 0.7151655423946472 15 P00813 1 +Positive regulation of microtubule binding 0.382120946538126 0.5441370226178736 0.5863471852765061 1.0 0.7161477612187752 2 Q15691 1 +Glucose import 0.4050986487143926 0.5421571938083707 0.587710221219347 1.0 0.7172503877584404 14 P52789,P31751,O75298,Q16539,P11166 5 +Axonal transport of mitochondrion 0.424829712258642 0.5405179324929603 0.5888398974978686 1.0 0.7178788053307027 5 O60313,P07196 2 +Negative regulation of cell development 0.3472448285850776 0.5389591922517684 0.5899150125435422 1.0 0.7188816075523231 22 Q9NQC3,Q96G23,P30536 3 +Eye morphogenesis 0.404516823264151 0.5386343648974682 0.5901391706159966 1.0 0.7189102636416249 14 P54802,Q8NBN7,O95140,Q15555 4 +Post translational protein modification 0.4286729513983467 0.5336160610898586 0.5936071938808247 1.0 0.7220174700305616 9 O60725 1 +Transcytosis 0.4283608928071666 0.531924811910363 0.5947780717796904 1.0 0.7226337711851515 9 P55899,P30533,Q15907 3 +Positive regulation of b cell activation 0.4115073961502758 0.5310434027200814 0.5953887028263944 1.0 0.7229606020997722 13 P60033,P00813,Q96FZ2 3 +Macrophage migration 0.4327012507254476 0.5291193399022526 0.5967226660887506 1.0 0.7241876862292924 7 P60033,P14174 2 +Positive regulation of cell cycle checkpoint 0.3947983635300909 0.5283914956022402 0.5972276389245161 1.0 0.7245311330420444 3 P12270,Q8N163 2 +Anterior posterior axis specification 0.4320637172241575 0.5257766946485297 0.5990433689367389 1.0 0.7264638886158336 7 Q15363 1 +Regulation of axon guidance 0.4098216895644718 0.5246257546593314 0.5998433793255447 1.0 0.7270024991702263 4 Q9UNW9,O14786,Q9BVA1 3 +Glycosylceramide metabolic process 0.4095772627200946 0.5233188764204376 0.6007523671053541 1.0 0.727455287045771 4 P04062 1 +Lipid homeostasis 0.316051641758085 0.5229896531031689 0.6009814536251952 1.0 0.727597724270266 29 O15260,Q96CP7,O15118,Q9NQ11,Q9BWH2,Q9NQC3,Q9Y6C9 7 +Bone mineralization 0.426622217390722 0.522514369107023 0.601312244480952 1.0 0.7278632174989161 9 P20020,O75844,Q4KMQ2 3 +Maintenance of location 0.279770407777785 0.5193826722171458 0.6034939123547698 1.0 0.730097898415852 70 P52789,P04062,P24390,P35670,O15258,O95202,Q96RL7,Q9H6V9,Q14534,O94901,O95674,P17900,P50416,Q9H4A6,O43292,Q8NEW0,P30536 17 +T cell mediated immunity 0.4008921965749976 0.5167477846799744 0.6053322342572154 1.0 0.7317794120798338 14 P60033,P30511 2 +Box c d snornp assembly 0.4080678164279472 0.5152586717069866 0.6063722746341242 1.0 0.732765310775928 4 Q9Y265,Q9NWS0,Q9Y230 3 +Double strand break repair via break induced replication 0.4249011676480513 0.5132208022857284 0.6077968761366588 1.0 0.7339433975989842 9 Q14566,P33993,Q9BRT9,Q9Y248 4 +Response to oxidative stress 0.282689564341167 0.5110407591984338 0.6093225164116454 1.0 0.7348341746046962 110 P04062,Q05086,O95168,Q9NR28,P16615,P00374,P09601,O43169,P30519,Q86Y07,Q9BYC5,Q8TED1,Q9UJ14,Q9NQ11,P03915,Q6NUK1,Q07820,Q15392,Q15165,P09493 20 +Cell maturation 0.3229517769015395 0.5105326623030271 0.6096783379384147 1.0 0.7351274824643464 25 P04062,Q96KR6,Q9NZJ7,O75503,P05067,Q86UL3,Q9Y2W6,Q15645,P09622 9 +Lymphocyte apoptotic process 0.3821796892324506 0.5073864127024007 0.6118837173809288 1.0 0.7372985870578419 16 P00813 1 +Cellular response to vitamin d 0.4183273588417683 0.5063809130061933 0.6125892711618377 1.0 0.737819697812634 5 Q8TB36 1 +External encapsulating structure organization 0.3151258299212157 0.5058881789930376 0.6129351512164138 1.0 0.7379639740207948 26 P05556,Q9Y5U9,Q8IYI6,P05067,Q53GQ0,Q92791,Q14118,P13674 8 +Lipid modification 0.2827786247951004 0.5048583685047624 0.6136583163624811 1.0 0.7386984121730181 53 Q9NTJ5,P04062,P28288,P16435,O14734,O43808,Q96N66,Q15067,Q2T9J0,O14975,Q53H12,P50416,Q9NRA0,Q9BWD1,A1L0T0,P23786,Q6IAA8,Q10713 18 +Development of primary female sexual characteristics 0.4174847787809741 0.502715291671897 0.6151644569675345 1.0 0.7398293248128344 11 O95470,Q05086 2 +Positive regulation of myoblast differentiation 0.3898305084745806 0.5011424343384699 0.616270884295907 1.0 0.7407505676088532 3 Q9NWT6,Q16539 2 +Positive regulation of proteolysis 0.2846733593165736 0.5007500921965704 0.6165470136232478 1.0 0.7409460428815466 98 Q96HY6,Q6IC98,P04062,Q9NZJ7,Q9Y3D6,Q9NR28,P61289,Q96A26,P51572,Q9P0J0,Q9BXK5,O14737,Q4ZIN3,Q9UL46,Q92542,Q9NWW5 16 +Protein kinase b signaling 0.3133336406095173 0.4992069659233202 0.6176335877182217 1.0 0.7418538575106413 29 Q86UE4,O00165,Q9NQC3,Q14118,Q13641 5 +Vacuolar localization 0.3544970625077238 0.4984084669815884 0.6181961701680088 1.0 0.7423812727845402 20 Q9UNH7,O95219,Q86YV9,P09601,Q9NRA0,Q9BZG1,P51809,Q6IAA8,Q99584 9 +Myeloid leukocyte activation 0.3352216689957799 0.4978371666611267 0.6185988172670203 1.0 0.7427281734631429 23 O95219,P09601,Q12846,P05067,P53634,Q9NRA0,P14174,Q9UNH7,Q99584 9 +Regulation of nucleotide biosynthetic process 0.4216444408748654 0.4956955137983841 0.6201092527396102 1.0 0.7437209630505558 9 Q9NRA0,P00403 2 +Bile acid metabolic process 0.4160965346146676 0.4950007983584965 0.6205995569603115 1.0 0.744172282850278 11 P28288,Q9H4L5,O14734,Q9BZF3,O15118 5 +Positive regulation of phagocytosis 0.4237411044689132 0.4939668676127546 0.6213295788787492 1.0 0.7449108339615197 8 Q08722 1 +Mammalian oogenesis stage 0.373064563248609 0.4929566878892815 0.6220431912304951 1.0 0.7453721290430402 2 Q96MU7 1 +Vesicle localization 0.2716108712272923 0.4929373051210434 0.6220568871057726 1.0 0.7453721290430402 60 O95721,P62820,Q15363,Q9NR31,Q8N6H7,Q92783,O00560,Q96A57,Q15907,P49755,Q9NQ11,Q9Y3E7,Q9HCU5,O43633,Q13561 15 +Lipid import into cell 0.4233871251904887 0.4920985267108776 0.6226496937227401 1.0 0.7456718401434688 8 P11166,P33121,O14975 3 +Production of sirna involved in rna interference 0.4033908213972521 0.4904017304800554 0.6238496523931083 1.0 0.7469718508478009 4 Q9UPY3,Q99598,O75569 3 +Ribose phosphate biosynthetic process 0.2827208682034202 0.4898001043197508 0.6242753568905177 1.0 0.7473444947334127 84 Q8WVC6,Q9UKU0,P24539,P00813,P00846,P50897,Q6Y1H2,P56385,P06576,Q8TB61,O75964,P00403 12 +Middle ear morphogenesis 0.4028693191957653 0.4876415188786652 0.6258037815987127 1.0 0.7483508126536722 4 P54802,O75569 2 +Regulation of myeloid leukocyte mediated immunity 0.4165380401659428 0.4821235572329327 0.6297181761308355 1.0 0.7522049869683612 10 O95219,Q9NRA0,P09601,Q12846 4 +Smoothened signaling pathway 0.3194703088695867 0.4819252191521634 0.6298590701462392 1.0 0.7522356403063757 25 P16435,Q9Y366,Q96J42,O43805,Q9BZG1,Q15738 6 +Tyrosine metabolic process 0.3857393337229687 0.4788679807721452 0.6320325509064944 1.0 0.7544173509448885 3 O43708,P61457 2 +Negative regulation of epidermal growth factor activated receptor activity 0.3854047409444305 0.4770532784639326 0.633324183244176 1.0 0.7556827395755769 3 Q9UNH7 1 +Activation of immune response 0.2899937804041425 0.4756765616964657 0.6343048214667502 1.0 0.75664559150809 48 P46379,P35232,Q08722,P60033,Q99623,P00813,P49770,Q9NR50,Q9UJZ1 9 +Ceramide catabolic process 0.4224233485520465 0.4755949867294133 0.6343629476598922 1.0 0.75664559150809 7 P04062,Q13510 2 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.4122928373062504 0.4749928654141582 0.6347920585724505 1.0 0.7570191009062763 5 P13674,P07237 2 +Microtubule anchoring 0.411417472449093 0.4691165072890489 0.6389863604958395 1.0 0.7611866717731459 11 O75381,Q15154,Q14118 3 +Striated muscle adaptation 0.3990624664545777 0.4675655638297046 0.6400952957622459 1.0 0.7622294948442068 4 P16615 1 +Regulation of glucose import 0.4106402988480816 0.4648354688452289 0.6420492855846613 1.0 0.7637807833676379 11 P52789,P31751,O75298,Q16539,Q9BZF1 5 +Collagen metabolic process 0.4101263567366102 0.462007386827546 0.64407602322258 1.0 0.7654473084843634 11 Q9UBG0,Q92791,P08670 3 +Positive regulation of membrane potential 0.4216639617612848 0.4616860414422367 0.644306482450562 1.0 0.7654473084843634 6 Q9UJZ1,Q8IWA4 2 +Negative regulation of neuron death 0.2920462081087249 0.4615416300096901 0.644410061115952 1.0 0.7654473084843634 46 P09601,P50897,Q4ZIN3,Q9NQ11,P30511,O76024,Q01105,P07196 8 +Negative regulation of double strand break repair via nonhomologous end joining 0.3822326125073044 0.4599036618490205 0.6455853716868989 1.0 0.766529884753015 3 Q9BRJ7,Q9UBB9 2 +Regulation of establishment of protein localization to mitochondrion 0.3428029786396284 0.4583657462519371 0.6466896966139877 1.0 0.7676422480313612 21 Q9Y371,P49257,Q9H300,O00165 4 +Regulation of cardiac muscle cell action potential 0.4168768067802952 0.4579181697762851 0.6470112324595907 1.0 0.7676422480313612 8 Q9HD47,P16615 2 +Glycerol ether metabolic process 0.4206731921760297 0.456672077781508 0.6479067633443749 1.0 0.7681684255561351 6 Q6IAN0 1 +Regulation of cholesterol metabolic process 0.4181671430570135 0.4536750401952655 0.6500627343307017 1.0 0.7698856185977542 7 P16435,O75477 2 +Stress induced premature senescence 0.3651767455448435 0.4490427836719819 0.653400793733967 1.0 0.7729975319853817 2 Q16539 1 +Regulation of mitochondrial membrane permeability involved in apoptotic process 0.4102985803446668 0.4483585604472261 0.653894443703128 1.0 0.7732226008405325 10 P45880 1 +Regulation of glucose transmembrane transport 0.3966197517657875 0.4446531021928629 0.6565704657931528 1.0 0.7747816342548267 13 P52789,P31751,O75298,Q16539,Q9BZF1,Q6ZWJ1 6 +Neuron maturation 0.4175736505239021 0.4410412067284615 0.6591831656202753 1.0 0.7767414630269237 6 Q9NZJ7,P05067 2 +Muscle system process 0.2714479189428929 0.4402451636579794 0.6597595522748394 1.0 0.7769091659648802 66 Q9HD47,P60660,P00813,P09601,P50402,P16615,Q14118,O43819,P09493 9 +Positive regulation of gliogenesis 0.4081827077903286 0.4369883664447164 0.6621197849838261 1.0 0.7783752847783931 10 Q14118 1 +Positive regulation of inflammatory response 0.3791106641714321 0.43490691174952 0.6636299974561608 1.0 0.7793241340094162 15 O95219,Q08722,Q99735,P60033,P05067,P53634,P51809 7 +Regulation of t cell activation 0.3007395334561775 0.4348887127857878 0.6636432078673935 1.0 0.7793241340094162 37 P00813,O96005,Q08722 3 +Vesicle fusion to plasma membrane 0.3927171294546162 0.4344048000262149 0.6639945127225322 1.0 0.779456245109277 4 O95721 1 +Synaptic transmission gabaergic 0.4038957397749103 0.4318415766308672 0.6658565592791017 1.0 0.7805175724603958 5 P51790 1 +Establishment of protein localization to vacuole 0.3616163356497529 0.4317351234960428 0.6659339365358572 1.0 0.7805175724603958 17 Q96RL7,P13473,Q14108 3 +Folic acid containing compound catabolic process 0.3619631901840445 0.4313500892970978 0.6662138348267961 1.0 0.7805175724603958 2 Q9NRN7 1 +Myeloid cell apoptotic process 0.3919906460099442 0.4306337018591113 0.6667347320521164 1.0 0.7807075032890074 4 P17987,P14174,P04083 3 +Regulation of myeloid cell apoptotic process 0.3919906460099442 0.4306337018591113 0.6667347320521164 1.0 0.7807075032890074 4 P17987,P14174,P04083 3 +Gliogenesis 0.2674693075170302 0.4298421478673828 0.6673104710224749 1.0 0.7810251358945073 57 P04062,Q96N66,O94901,Q96G23,P08670,P49770,Q9NQC3,Q14118,Q92542,P30536 10 +Positive regulation of myelination 0.3917077437695106 0.4291666582246652 0.6678019452197284 1.0 0.7810251358945073 4 Q14118 1 +Dendritic cell chemotaxis 0.391667297345061 0.4289569833239457 0.6679545299213321 1.0 0.7810251358945073 4 Q4KMQ2 1 +Positive regulation of hydrolase activity 0.2798062033149642 0.4279003429090732 0.6687236774405254 1.0 0.7816344075795434 97 Q96HY6,Q6IC98,Q9NZJ7,Q9Y3D6,P35232,Q9NR28,P61289,Q96A26,Q99623,Q9P0J0,P51572,Q9BXK5,O14737,P07602,Q9UL46,Q8IZ81,Q92542 17 +Glutamate biosynthetic process 0.3758612327685153 0.4257738136166418 0.6702726700002377 1.0 0.7828043804055821 3 O75746 1 +Female sex differentiation 0.4007118504556605 0.4257030810776807 0.6703242166769614 1.0 0.7828043804055821 12 O95470,Q05086 2 +Leukocyte mediated cytotoxicity 0.3547724881777111 0.4214683361861662 0.6734131279688151 1.0 0.7852877633762817 18 P30511,P11279 2 +Peptide transport 0.3014501701705106 0.4189273398205816 0.6752692355344845 1.0 0.7869910763247039 34 Q8N183,P62820,Q03519,Q9BRT2,Q15907,Q12846,P50416,Q8N5M9 8 +Regulation of nik nf kappab signaling 0.3764571841811737 0.4188086175277801 0.6753560063681052 1.0 0.7869910763247039 15 Q99623,O43657,P35232 3 +Fibroblast proliferation 0.3838627287657025 0.415510440334167 0.677768273893322 1.0 0.7889570777417272 14 O75844 1 +Oligosaccharide metabolic process 0.4122425224097338 0.4143605979009709 0.6786100407272739 1.0 0.7895952639526217 6 Q9BYC5,P10253,P17900 3 +Interleukin 12 production 0.4103043019388006 0.4136052800402727 0.6791632057435617 1.0 0.7895952639526217 7 Q08722,Q16539 2 +Negative regulation of epithelial cell apoptotic process 0.4071289128262044 0.4074452337376469 0.6836810101888193 1.0 0.7937168121132159 8 P09601,O76024 2 +Macrophage differentiation 0.4106826209358704 0.4066050323809922 0.6842981005506756 1.0 0.7942919630858482 6 P04062 1 +Regulation of peptidyl tyrosine phosphorylation 0.3022214933299507 0.4062540723930842 0.6845559274366069 1.0 0.7944499723210968 30 O95684,O00165,P60033,P05067,P18031,P61225,P14174,Q9UNH7 8 +Positive regulation of t cell proliferation 0.3995173936776135 0.4041908681604693 0.6860723683743604 1.0 0.7954722250991133 11 P30825,P60033 2 +Natural killer cell activation 0.4064688613367358 0.4040609395593638 0.6861679074039686 1.0 0.7954722250991133 8 P30511,P46379,P11279 3 +Hepaticobiliary system development 0.2988244451197065 0.4016447948253554 0.6879454581155793 1.0 0.7973624758945608 35 O75844,P00813,P09601 3 +Activation of cysteine type endopeptidase activity 0.3978613783391393 0.4012514855476103 0.6882349781812163 1.0 0.7974437233878203 5 Q12797,Q96F07,Q9BXI6 3 +Chromosome organization involved in meiotic cell cycle 0.3647028669101219 0.3970851235336966 0.6913046897570814 1.0 0.8001484068677708 16 O94901,Q92791,O60566,Q15645,Q9BTX1 5 +Copii coated vesicle budding 0.3337604801077127 0.3933308165782615 0.6940751603208444 1.0 0.8025013543348339 21 Q15363,P62820,Q9NR31,P49755,Q5JRA6 5 +Negative regulation of organ growth 0.3843905290850579 0.391520701604261 0.695412389783566 1.0 0.8033360609639287 4 P49840,O94826,Q13043 3 +Erythrocyte maturation 0.3843905290850562 0.3915207016042523 0.6954123897835724 1.0 0.8033360609639287 4 O95696,Q96KR6,P18074 3 +Aspartate family amino acid metabolic process 0.3211953025393723 0.3905830319331763 0.6961054698711633 1.0 0.8035679058035285 23 O75746,Q9BQT8,Q9UJS0,Q13126,Q9BV57 5 +Prostanoid biosynthetic process 0.4073704443254475 0.3902182222571536 0.6963751881762492 1.0 0.803737133736661 6 Q9H7Z7,Q8NCG7 2 +Phosphatidylcholine biosynthetic process 0.4052277083079241 0.3880536754193092 0.6979763125485454 1.0 0.8051580435265779 7 Q8NF37,Q86UL3 2 +Regulation of dna damage response signal transduction by p53 class mediator 0.3983278575329859 0.3846188735449275 0.700519808811884 1.0 0.8069513520247007 10 O75844 1 +Regulation of response to interferon gamma 0.3670368205727676 0.3792711017972353 0.7044865568345973 1.0 0.8098306799469037 3 Q15648,Q16543 2 +Regulation of monocyte chemotaxis 0.3934516108215009 0.3791402113830678 0.7045837471063674 1.0 0.8098306799469037 5 Q4KMQ2 1 +Histone h3 k9 trimethylation 0.380740755933926 0.3729704438258031 0.7091704417571967 1.0 0.8140433697539968 4 Q9NWS0 1 +Regulation of histone h3 k9 trimethylation 0.380740755933926 0.3729704438258031 0.7091704417571967 1.0 0.8140433697539968 4 Q9NWS0 1 +Smooth muscle cell proliferation 0.3473448604516037 0.3725527042922432 0.7094813790180985 1.0 0.8140548946023759 18 P09601,P35232,P09493 3 +Response to toxic substance 0.2767905584285594 0.370624161056762 0.7109174838199839 1.0 0.8148808445853856 50 P35670,P27544,Q99735,P00374,Q8TED1,Q8TC12,Q15165,Q9Y5Z9 8 +Negative regulation of helicase activity 0.3652834599649312 0.3701467651322217 0.7112731391616853 1.0 0.8148808445853856 3 P49736,P33993 2 +Fermentation 0.3652834599649296 0.3701467651322124 0.7112731391616922 1.0 0.8148808445853856 3 O75746,Q9NQ88 2 +Glycolytic fermentation 0.3652834599649296 0.3701467651322124 0.7112731391616922 1.0 0.8148808445853856 3 O75746,Q9NQ88 2 +B cell proliferation 0.3924974259009708 0.366583394578809 0.7139297964012639 1.0 0.8168039575982284 11 P00813 1 +Spermidine metabolic process 0.3642181715751146 0.3646228676659264 0.7153929424628362 1.0 0.8177350951492549 3 P49366 1 +Cellular response to estradiol stimulus 0.3903943386642103 0.3639390274200916 0.7159035404985106 1.0 0.8180942784375522 5 Q96KR6 1 +Cell activation involved in immune response 0.2891913143651722 0.3638663487250623 0.7159578144475698 1.0 0.8180942784375522 41 Q9UNH7,P60033,P00813,P09601,P05067,P30511,P11279,Q9NRA0,Q96FZ2,Q99584 10 +Intermediate filament based process 0.3892519296848656 0.3629833579323985 0.7166173161676859 1.0 0.8184180965609961 12 Q16352,P08670 2 +Monocarboxylic acid transport 0.3980739999785057 0.3614224769131016 0.71778364783964 1.0 0.819320100209332 8 P28288 1 +Immune response regulating cell surface receptor signaling pathway 0.2971609428263558 0.36005659416744 0.7188048116763563 1.0 0.8201988831713432 29 P46379,Q08722,P60033,P00813,P49770,Q9NR50 6 +Cellular response to toxic substance 0.2971473323682211 0.3579180953853104 0.720404608448383 1.0 0.8213450273063152 28 P27544,Q99735,P00374,Q8TED1,Q8TC12 5 +Cellular response to retinoic acid 0.3931841683639305 0.3577048800806347 0.7205641806653289 1.0 0.8213450273063152 10 Q99623 1 +Response to ph 0.4006821753915253 0.3574817138478446 0.7207312132806727 1.0 0.8213919972584203 6 Q15907 1 +Protein hydroxylation 0.3578082356922687 0.3546055142003924 0.72288514456051 1.0 0.8229022788215256 16 O75718,Q12797,Q92791,O15460,P07237,P13674 6 +Regulation of epithelial cell migration 0.2870651259195602 0.354365655095992 0.723064869993914 1.0 0.8229022788215256 42 P57105,Q9NQC3,P09601 3 +Endocytic recycling 0.2962882633257618 0.3486842223671128 0.7273263904844298 1.0 0.8263116388935534 26 O43752,Q15057,Q15907,Q15904,Q9UBQ0 5 +T cell activation 0.2607410111085297 0.3478736501971763 0.7279350748775646 1.0 0.8264644457540558 57 P30825,P24390,Q08722,P60033,P00813,Q92542,O96005,P78310 8 +Fluid transport 0.3609614016357724 0.3478307372050133 0.727967304394274 1.0 0.8264644457540558 3 Q93063 1 +Regulation of adherens junction organization 0.3461875547765068 0.3464163501950641 0.729029839248724 1.0 0.8275268284847279 2 P35611 1 +Positive regulation of production of molecular mediator of immune response 0.2957587421325639 0.3443622353392149 0.7305738858584898 1.0 0.8284152035581417 26 P35232,P60033,Q99623,P30511,Q9NRA0,P14174,Q96FZ2 7 +Vesicle targeting 0.3265858379941995 0.3426369058262522 0.7318716340662803 1.0 0.829454518608451 21 O95721,Q15363,Q9NR31,Q8N6H7,P49755,Q9HCU5 6 +Golgi to vacuole transport 0.3936477076419971 0.3392628937847187 0.7344116932059941 1.0 0.831755644213867 8 P11279 1 +Placenta development 0.3142571718814637 0.3387118354877521 0.7348268237460576 1.0 0.8320814406616241 23 Q15363,P35613,Q15738,P00813 4 +Positive regulation of intrinsic apoptotic signaling pathway 0.3551015116247782 0.3381165622969638 0.7352753498998104 1.0 0.8324449330811589 16 Q9Y3D6,Q07820,O60443 3 +Sphingolipid mediated signaling pathway 0.3729903536977489 0.3341262566820158 0.7382842875643785 1.0 0.834982645395056 4 P31749,P15311,Q9NRA0 3 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.3942524835897502 0.3337725866124251 0.7385511710037325 1.0 0.8351136830223072 7 Q9Y2U8,Q92896 2 +Brown fat cell differentiation 0.3942240252556427 0.3336336724992843 0.7386560057859684 1.0 0.8351136830223072 7 Q6IAN0,O75192 2 +Chondrocyte differentiation 0.3861003945301911 0.3328223976855208 0.7392683502757298 1.0 0.8355218552769508 11 P16435,Q15043,Q9NX62,Q92896 4 +Outer ear morphogenesis 0.3579777907656374 0.3325775328675123 0.7394532050118952 1.0 0.8355808416682796 3 O75569,P27361 2 +Positive regulation of sequestering of triglyceride 0.3432661408121537 0.3310786567627007 0.7405850728086139 1.0 0.8364397544793524 2 O60664 1 +Regulation of actin filament based movement 0.391647225746895 0.3293258372042004 0.7419094170688627 1.0 0.836716142645915 8 Q9HD47 1 +Negative regulation of erk1 and erk2 cascade 0.375762134105139 0.3274968275105025 0.743292142070203 1.0 0.837654063878644 13 P57105,P35232 2 +Endocytosis 0.2635761855280711 0.3240930638244357 0.7458675780399537 1.0 0.8394433602752133 126 O15260,Q05086,Q4KMQ2,P51790,P05067,P62820,Q5VW38,P27824,Q96ED9,P18031,Q14108,Q9BZG1,O00560,P60033,P57105,Q9NX40,O60749,Q9NUN5,O15118,P50897,Q5JRA6,Q8NBU5 22 +Interleukin 1 production 0.3819752652994268 0.3239742131838876 0.7459575571318187 1.0 0.8394433602752133 12 P49755,Q99584 2 +Regulation of protein tyrosine kinase activity 0.3840964684893596 0.3223541034216011 0.7471844500789284 1.0 0.8405342219740212 11 O95684,P18031,P61225,P05067 4 +Response to arsenic containing substance 0.3747409853069342 0.3219027383526373 0.747526378615416 1.0 0.8407250138730504 13 P09601 1 +Cardiac muscle cell membrane repolarization 0.3911619421798128 0.3187456343589651 0.749919406908625 1.0 0.8425944730291746 7 O75844 1 +Late endosome to vacuole transport 0.3871519425397616 0.3161937295717572 0.7518554668688702 1.0 0.8440434200722243 9 Q9Y3E7,Q92783,O43633,Q9BRG1 4 +Positive regulation of epithelial cell migration 0.2913249891389589 0.3159338718696413 0.7520527016227587 1.0 0.8441196760992724 31 Q9NQC3,P09601 2 +Regulation of nucleotide metabolic process 0.3281643949563725 0.3153896953679577 0.7524657898111105 1.0 0.8442930003243261 20 O75746,P36404,P05067,Q9NRA0,O75376,Q15118,P00403 7 +Phospholipid dephosphorylation 0.3793005419026097 0.3097402754075018 0.7567584725751959 1.0 0.8482563828440634 5 Q9NTJ5 1 +Neurotransmitter transport 0.2976430646109393 0.307093763949979 0.7587720041764716 1.0 0.8498067621792104 25 O95721,P05556,P20339,Q9P253,P50897,Q12846,P16615 7 +Positive regulation of protein secretion 0.3036427634031032 0.3050661352010136 0.760315782750423 1.0 0.8509893471561629 24 Q9Y5U9,P49755,Q9NQ11,Q9H4A6,Q9NV70 5 +Oocyte maturation 0.3782571776662237 0.3047257343343954 0.7605750480396047 1.0 0.8510158581047418 5 Q15645 1 +Mitochondrial outer membrane permeabilization involved in programmed cell death 0.3820210889167164 0.3004203803417857 0.7638565199698701 1.0 0.8539139678998293 10 P45880 1 +Regulation of cellular response to transforming growth factor beta stimulus 0.3797552795134135 0.2998631310641264 0.764281558054086 1.0 0.8540277321083659 11 Q92896,Q9Y2U8,O00560 3 +Regulation of response to oxidative stress 0.3027920840082971 0.2986583564336915 0.7652007343106588 1.0 0.8546444175959106 24 Q9UJ14,P00374,Q07820 3 +Neutral lipid metabolic process 0.3485258953800224 0.2985423542964998 0.7652892549887735 1.0 0.8546444175959106 16 Q9NUQ2,Q96N66,Q92604,Q9UBV2,P50416,Q86UL3,Q8NCG7 7 +Golgi to plasma membrane protein transport 0.3358076226232244 0.2982818737321333 0.7654880376353077 1.0 0.8546444175959106 18 P61026,Q9H4A6,Q9BZG1 3 +Protein localization to plasma membrane 0.2667386596829237 0.2978625558955046 0.7658080674973724 1.0 0.8547961048698322 78 Q15363,Q9HD47,O15400,O15258,P60033,Q9UNK0,Q9H4A6,O00264,P35613,Q9BXS4,P61026,Q9UEU0,Q9BZG1,Q13641 14 +Positive regulation of mononuclear cell migration 0.3807444125605437 0.2939754410794193 0.7687766697974214 1.0 0.8578759146047124 10 Q8NHP6,Q4KMQ2,Q08722,P05067 4 +Synaptic transmission glutamatergic 0.3748138857434255 0.2882846447177928 0.773128860194197 1.0 0.8616718844755854 5 P51790 1 +Negative regulation of response to endoplasmic reticulum stress 0.3683197099173109 0.2870742311686891 0.7740554826600612 1.0 0.8622925240281364 13 Q96HY6,P18031,O60313,O76024 4 +Basement membrane organization 0.3857210220042669 0.286166049079364 0.7747509457644077 1.0 0.862920009204923 6 Q14118 1 +Regulation of monooxygenase activity 0.3810198241306355 0.2857360322598339 0.7750803049696953 1.0 0.8631395821975727 9 P00374 1 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.3735357300990041 0.2822247978100006 0.7777711449569207 1.0 0.8658407289015652 5 Q8N2F6 1 +Negative regulation of myelination 0.3330411919368898 0.2784968075218856 0.780631015375618 1.0 0.8679882930287913 2 P53634 1 +Negative regulation of nervous system process 0.3330411919368898 0.2784968075218856 0.780631015375618 1.0 0.8679882930287913 2 P53634 1 +Negative regulation of cytokine production involved in inflammatory response 0.332749050540462 0.2770211431660267 0.7817638713312167 1.0 0.8689201463895255 2 Q9BWS9 1 +Phosphatidylcholine metabolic process 0.3595193305884173 0.2767970816391861 0.7819359221695237 1.0 0.8689201463895255 14 Q8NF37,Q86UL3,Q96N66,Q6IAN0 4 +Regulation of endothelial cell migration 0.2866903659686686 0.2767116698228773 0.7820015104225586 1.0 0.8689201463895255 31 P57105,P09601 2 +Cerebellar cortex morphogenesis 0.3819363159438437 0.2746343406430179 0.7835971804034902 1.0 0.8702487910299396 7 Q96D53 1 +Negative regulation of canonical wnt signaling pathway 0.3262029662029037 0.2684512869746776 0.7883519664168899 1.0 0.8744879586694064 19 P50402,Q9UKV5,Q13641,Q8NBM4 4 +Regulation of cell activation 0.2603972492473749 0.2675096979340297 0.7890767482992722 1.0 0.8751075599263739 70 Q08722,P60033,P00813,P09601,O96005,P30511,Q9BWH2,P11279,Q96FZ2 9 +Substantia nigra development 0.3429461817801693 0.2655439847128601 0.7905904307046181 1.0 0.8760237468278895 16 P24539 1 +Neutrophil migration 0.3503399425642829 0.265437031622714 0.7906728118317015 1.0 0.8760237468278895 15 Q8N5M9,P35613 2 +Pigmentation 0.3352047473446858 0.2653585590114861 0.7907332572218109 1.0 0.8760237468278895 17 O75787,Q8TAA9,Q15907,Q13561 4 +Macrophage proliferation 0.3580824320374166 0.2617648247308322 0.7935027594841804 1.0 0.8784103805176751 4 Q05397,P04062,P27361 3 +Vesicle budding from membrane 0.2825002110146989 0.2609400801167683 0.7941387157830158 1.0 0.8788687916477488 36 Q15363,P62820,Q9NR31,Q8N6H7,P49755,Q9H4A6,Q5JRA6,Q9HCU5 8 +Inflammatory response 0.2603833716340383 0.259877570615889 0.7949582130540205 1.0 0.8789949618335718 71 P04062,Q4KMQ2,Q08722,Q99735,P60033,Q8IV08,P00813,P09601,P05067,Q9BQE5,Q6IAN0,Q8NCG7 12 +Sequestering of triglyceride 0.3433664523670376 0.2598579028973823 0.7949733845994804 1.0 0.8789949618335718 3 Q9BZF1,O60664 2 +Regulation of sequestering of triglyceride 0.3433664523670376 0.2598579028973823 0.7949733845994804 1.0 0.8789949618335718 3 Q9BZF1,O60664 2 +Regulation of presynaptic cytosolic calcium ion concentration 0.3292433537832234 0.2594358050299676 0.7952990067287802 1.0 0.8792060822905127 2 P20020 1 +Membrane invagination 0.3688689835646316 0.2555802284049204 0.7982749868998673 1.0 0.8820479205284926 12 P51790,Q4KMQ2 2 +Postsynaptic cytoskeleton organization 0.3790523577699366 0.2553373668853104 0.7984625415835431 1.0 0.882105850644334 6 Q16352 1 +Regulation of natural killer cell mediated immunity 0.3746296519700345 0.2545706400085332 0.7990547380788788 1.0 0.8825991067343933 9 P11279 1 +Positive regulation of receptor mediated endocytosis 0.3728004026287709 0.2544092181714082 0.7991794301328123 1.0 0.8825991067343933 10 P50897 1 +Positive regulation of lymphocyte mediated immunity 0.3080257058357296 0.2524758968351425 0.8006732423091059 1.0 0.8838428377897813 22 P60033,P30511,O15400,P11279 4 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.3478941665147488 0.2516328559691484 0.8013248602102712 1.0 0.8843636145555958 15 O43657 1 +Actin filament based movement 0.2839743979205529 0.2506142079913607 0.8021123958352359 1.0 0.884640939349961 29 Q9HD47,Q9UM22,P60660,P16615,P36383,P05023,P09493 7 +Regulation of protein targeting 0.2836893711323638 0.2482988822389771 0.803903163776563 1.0 0.8861668107283693 29 Q9Y3D6,O00165,P49257,O43464,O14737,Q9H300,P27105,O95429,Q9Y371 9 +Non lytic viral release 0.374589961323593 0.2467847121347061 0.805074842573932 1.0 0.8871587731807272 8 O43633 1 +Negative regulation of intracellular estrogen receptor signaling pathway 0.3767970886691789 0.2450582919509956 0.8064112965833039 1.0 0.8883315801714153 6 Q99623 1 +Positive regulation of cell aging 0.3654970760233941 0.2446757474621196 0.8067075080667294 1.0 0.8884642558271503 5 P78540,Q96IZ0,P02545,O43324 4 +Regulation of anion channel activity 0.3398597311513762 0.2429395400969049 0.8080522343759122 1.0 0.8894421680892963 3 Q9HD26,P08183 2 +Ribonucleotide catabolic process 0.3699389153556588 0.2403956276853028 0.8100235674443526 1.0 0.8909576829446897 10 P00813 1 +Regulation of intracellular protein transport 0.262680978524806 0.2380427553482253 0.8118479331571304 1.0 0.8926635182162284 79 Q9NR31,Q9GZP9,Q9Y282,O00165,P60033,P49257,Q9Y3D6,Q92544,P51572,Q8NBM4,O14737,Q15154,Q9NQ11,P50402,Q9H300,Q9Y371 16 +Vasoconstriction 0.3521773087676114 0.2340664050966556 0.8149334263703127 1.0 0.8957518234522113 4 P42892 1 +Cellular response to starvation 0.2806916995996958 0.2320226881009328 0.8165203920399569 1.0 0.8970456276063342 33 P13473,P21964,Q9Y371 3 +Sodium ion transmembrane transport 0.3103215551728079 0.2314219250907498 0.8169870336582401 1.0 0.8973322143063343 21 Q9HD47,Q4KMQ2,P08195,Q9Y6M7,P27105,P55011,P05023 7 +Positive regulation of cell cell adhesion 0.281441674559253 0.2312572040092115 0.817114991810864 1.0 0.8973322143063343 30 P00813,Q08722 2 +Immune effector process 0.2625767276980487 0.2311559763530262 0.8171936296034248 1.0 0.8973322143063343 80 O15400,P35232,Q08722,P60033,Q99623,P00813,P09601,P05067,Q8N5M9,P30511,P11279,Q96FZ2,Q99584 13 +Negative regulation of lipid localization 0.3619335815847447 0.2283569351427089 0.8193687657469793 1.0 0.899115700587709 5 P31751,Q9Y3D6 2 +Monocyte chemotaxis 0.3718711982565389 0.227905332743928 0.8197198368852836 1.0 0.8993497638969968 7 Q4KMQ2 1 +Nuclear migration 0.3497001036239696 0.2234607630402722 0.8231769175929915 1.0 0.9028254172175972 14 Q15154,O94901,Q5SNT2 3 +Bleb assembly 0.360819720933352 0.2232991979453415 0.8233026514547113 1.0 0.9028254172175972 5 Q9NR77 1 +Histamine secretion 0.349379907466595 0.2211541420399683 0.8249724145108777 1.0 0.9039693900627412 4 O95219,Q9UNH7 2 +Histamine production involved in inflammatory response 0.349379907466595 0.2211541420399683 0.8249724145108777 1.0 0.9039693900627412 4 O95219,Q9UNH7 2 +Histamine transport 0.349379907466595 0.2211541420399683 0.8249724145108777 1.0 0.9039693900627412 4 O95219,Q9UNH7 2 +Insulin secretion 0.2803578769135184 0.2210696013699817 0.8250382392760129 1.0 0.9039693900627412 27 Q8N183,P50416,Q15907,Q8N5M9 4 +Microtubule nucleation 0.3276550923103116 0.2200966140961029 0.8257959117189817 1.0 0.904495924782133 17 Q96RT7 1 +Cell communication by electrical coupling involved in cardiac conduction 0.3710214309947044 0.2190914247794752 0.8265788305434056 1.0 0.905201577887494 6 P05023 1 +Labyrinthine layer development 0.3692679481053538 0.2160771653608262 0.8289275986756997 1.0 0.9074074108656214 7 Q15363 1 +Positive regulation of histone phosphorylation 0.3340151957919304 0.2152474202962198 0.8295744212381326 1.0 0.9078728955310194 3 P50750,P27361 2 +Developmental maturation 0.2690891559522042 0.2130861711267649 0.8312597507946622 1.0 0.90941237693775 45 P04062,Q96KR6,Q9NZJ7,Q15125,O75503,P51790,P05067,O75787,Q86UL3,Q9Y2W6,Q14118,Q15645,P09622,P07196 14 +Regulation of b cell activation 0.3166273023888897 0.2080345985389552 0.8352019525632399 1.0 0.9135721089699784 19 P60033,P00813,Q96FZ2 3 +Apical protein localization 0.346389944460684 0.2075082175157813 0.8356129756916726 1.0 0.9138571634224568 4 Q9HD26,P54920,P18085 3 +Microtubule based transport 0.2477364815098328 0.2073423085296013 0.8357425345637357 1.0 0.9138571634224568 59 O75665,P62820,O94901,O60313,Q9Y366,Q5SNT2,P05067,O75381,Q15154,P11279,O43805,P07196 12 +Response to misfolded protein 0.3643239313696054 0.2056635295612856 0.8370537487028615 1.0 0.9151376438674058 9 Q9BUN8,P46379 2 +Regulation of establishment of protein localization 0.2581406344309302 0.204409354131557 0.8380336209673904 1.0 0.9160555053039392 145 Q8N183,Q9GZP9,Q9BRT2,P49257,Q9Y5U9,P50416,Q9H300,Q9NR31,Q92544,O14737,P49755,Q96KC8,Q9Y282,O00165,P60033,P51572,Q16850,Q15154,Q9NQ11,Q9H4A6,Q8NBM4,Q9Y3D6,Q8N5M9,P50402,P98194,Q9Y371 26 +Substrate dependent cell migration 0.3652727843934218 0.2035558521982798 0.8387005955741844 1.0 0.9166310878801732 8 P06576,O00560 2 +Negative regulation of locomotion 0.2666938642106977 0.2017046505604557 0.8401476267075716 1.0 0.9180588729740587 46 P57105,P00813,P09601,Q96G23,P61225,Q5JRA6,Q14118,P09493 8 +Cellular response to vitamin 0.3664814273179162 0.1990574904527773 0.8422177734364384 1.0 0.920012989456672 6 Q8TB36,Q13573,Q96C86,P20020,Q15648 5 +Response to vitamin d 0.3664814273179164 0.199057490452777 0.8422177734364387 1.0 0.920012989456672 6 Q14258,Q8TB36,Q13573,P20020,Q15648 5 +Regulation of nitric oxide metabolic process 0.3565567728966634 0.1938624587202475 0.846283579586562 1.0 0.924145066500682 12 Q08722 1 +Nucleus localization 0.337013687498233 0.1916253401416873 0.8480356917840786 1.0 0.9259034948932036 15 Q15154,O94901,Q5SNT2 3 +Neutrophil degranulation 0.3287551139684427 0.1908945818823938 0.8486081851491645 1.0 0.9262187314251372 3 P12429,P51809 2 +Neutrophil activation involved in immune response 0.3287551139684427 0.1908945818823938 0.8486081851491645 1.0 0.9262187314251372 3 P12429,P51809 2 +Regulation of cartilage development 0.3532668330727568 0.1895695819424891 0.8496464250417581 1.0 0.9270419292449602 5 P16435 1 +Regulation of chondrocyte differentiation 0.3532668330727568 0.1895695819424891 0.8496464250417581 1.0 0.9270419292449602 5 P16435 1 +Leukocyte apoptotic process 0.3032540362315816 0.1850222774139187 0.8532115623881988 1.0 0.9307358789638596 21 P00813 1 +Inner cell mass cell proliferation 0.3402513884828972 0.1800164778900995 0.8571396320361047 1.0 0.9347490006568144 4 P61201,Q9BRT9,O75312 3 +Positive regulation of membrane permeability 0.3553678561273583 0.1789699601654114 0.8579612891521022 1.0 0.9354829546028738 11 P45880 1 +Adaptive thermogenesis 0.2747544441150008 0.1787942577114527 0.8580992543140331 1.0 0.9354829546028738 26 P05141,O95140,Q96H78,Q6IAN0,P23786,P12235 6 +Cytoplasmic pattern recognition receptor signaling pathway 0.3115653164763186 0.1769772437343519 0.8595262642849226 1.0 0.9368821928956378 19 O43657 1 +Cell cell adhesion via plasma membrane adhesion molecules 0.31569029423382 0.175032585321041 0.8610540294151834 1.0 0.938390768618083 18 P05556,P35613,P98194,Q9Y639,P78310,P10586 6 +Bone development 0.2790535911386873 0.1669204819392126 0.8674326169871067 1.0 0.9448690344888756 25 P16435,Q15125,Q92896,Q9NX62,Q15904,O75844,Q93063 7 +Astrocyte development 0.3587561524197131 0.1657802394978333 0.8683298975210909 1.0 0.9456886171200668 6 P08670 1 +Regulation of inflammatory response 0.2689603644118272 0.1654528862929916 0.8685875299680936 1.0 0.9458114087792686 40 P04062,O95219,Q16539,Q99735,Q08722,P60033,P00813,P05067,P53634,Q8N2K0,P51809,Q9UNH7,Q8NCG7 13 +Mitochondrion localization 0.3090683413419827 0.161901625121472 0.8713833230425239 1.0 0.948697520483922 19 O60313,O95140,Q8IWA4,Q9NVT9,O75153,Q9UH62,P07196 7 +Response to fatty acid 0.3516216905610135 0.1613352875490828 0.8718293318456123 1.0 0.9490248254607564 11 O00767,P33121,P11802,P13010,P50416 5 +Urogenital system development 0.26657643840716 0.1591367429498432 0.8735611403772585 1.0 0.9504903377317332 42 O95470,Q9NZJ7,O75844,P07602 4 +Regulation of lipid transport 0.3129659060328295 0.1590716259414662 0.8736124427681371 1.0 0.9504903377317332 18 O15260,P33121,Q9Y3D6,Q9BZF3,P14174,Q6IAA8,P30536 7 +Regulation of hormone secretion 0.2722848706651283 0.1588838676450255 0.8737603709890625 1.0 0.9504928681580735 27 Q8N183,O95219,Q9BRT2,Q12846,Q16836,P50416,Q8N5M9,Q6ZWJ1,P51809,Q9UNH7 10 +Polyol biosynthetic process 0.3371750934576491 0.1581299464804266 0.8743544035954596 1.0 0.9509805975793336 14 Q13510,P04062,O15269,P00374 4 +Xenobiotic transport 0.3566555561012068 0.1569172174174565 0.8753100904210074 1.0 0.951861447654229 6 P11166,P35670,P33527 3 +Midbody abscission 0.351884903402261 0.1552461311698472 0.8766272817017502 1.0 0.9529040014102738 10 O95235,O43633 2 +Detoxification 0.2719573297675219 0.1552105157265396 0.8766553584024461 1.0 0.9529040014102738 29 P35670,Q99735,P00374,Q8TED1,Q8TC12 5 +Programmed cell death 0.2479268526650637 0.1551453707129819 0.8767067145327978 1.0 0.9529040014102738 439 Q96HY6,Q6IC98,P04062,Q86UE4,Q4KMQ2,Q9NR28,Q9Y241,Q96A26,Q99623,Q9Y5U9,Q14728,Q9BXK5,Q96RU2,Q8N2F6,O60443,P05067,Q8IWB1,Q9BUP3,Q9NQC3,Q9NS69,Q9H300,O76024,Q9Y2C4,Q01105,Q12981,O15269,Q9UHX1,Q96KA5,Q92542,P07196,P14174,P52789,O95470,P16435,P24390,Q9NVI7,O95197,Q5J8M3,Q3ZCQ8,P00813,Q9P0J0,P09601,O14737,P12236,P45880,Q6NUQ4,O60566,P11279,P21796,Q13510,P12235,P30536,Q9NZJ7,O00165,Q9UDX5,P51572,P05141,O60313,Q9NQX7,Q86XL3,Q9H4A6,O75844,Q9Y6C9,Q15041,Q9Y3D6,P35232,P61289,Q9H3K2,O95140,P50897,O14681,Q07820,Q15392,Q96JJ3,Q9Y371 75 +Sensory system development 0.2674547912947124 0.1519855860497239 0.8791983042410685 1.0 0.955135052435629 40 P54802,P48681,O95140,P08670,Q99471,O75569,P20020,Q8NBN7,Q9NP72,Q8NF37,O43819,Q99797 12 +Regulation of ossification 0.3504625677189712 0.1487980468158624 0.8817129918971507 1.0 0.9572297374196906 10 O75844,Q4KMQ2,Q16539 3 +Mononuclear cell differentiation 0.2644753232192657 0.1483782278791407 0.8820442815040583 1.0 0.957430174535832 43 P24390,P05141,P00813,P55327,O96005 5 +Positive regulation of cytokine production involved in immune response 0.3470021415901591 0.1479167646200669 0.882408457493093 1.0 0.95766623616208 12 P60033,P30511,P14174 3 +Regulation of muscle system process 0.2688763776215004 0.1474042894871098 0.8828129199868833 1.0 0.957945934453852 37 Q9HD47,P00813,P16615,Q14118,P09493 5 +T cell mediated immune response to tumor cell 0.318819403857396 0.1464811572385671 0.8835415638145838 1.0 0.9584179675276842 3 P04439,P09429 2 +Positive regulation of interleukin 12 production 0.3188194038573959 0.1464811572385671 0.8835415638145838 1.0 0.9584179675276842 3 P09429,Q16539 2 +Vesicle mediated transport to the plasma membrane 0.2509943922714267 0.1460208066762564 0.8839049631238005 1.0 0.95865286580365 53 P98194,O43752,Q15057,Q9UBQ0,Q15907,Q9H4A6,Q9NV70,Q15904,P61026,Q9BZG1 10 +Neuromuscular process controlling posture 0.3047034764826136 0.1434331193662933 0.8859481279142116 1.0 0.9603901326841536 2 P10253 1 +Gland morphogenesis 0.3401421201980112 0.1426350136013683 0.8865784433434629 1.0 0.9607543290415216 13 Q99623 1 +Cellular pigmentation 0.349052229372483 0.142444666034768 0.8867287836661062 1.0 0.960757759298314 10 Q15907,Q13561 2 +Lymphocyte activation involved in immune response 0.2701130586702601 0.1415198970422896 0.8874592426610601 1.0 0.9613327424266188 28 P60033,P30511,P00813,P11279 4 +Chemokine c c motif ligand 5 production 0.3176504967855078 0.1413999563430994 0.8875539887569288 1.0 0.9613327424266188 3 P78540,Q7Z434 2 +Negative regulation of response to external stimulus 0.2537324776280423 0.1410431737932271 0.8878358354746949 1.0 0.9614784893793644 51 P80303,P00813,Q96G23 3 +Regulation of defense response to virus 0.3135056112433099 0.1387778432103443 0.8896257030977492 1.0 0.962937587435269 17 O75844 1 +Regulation of phospholipid metabolic process 0.3464895629708322 0.1376333889649816 0.8905301660624736 1.0 0.963756784492014 11 Q99623,Q96DA6 2 +Regulation of action potential 0.346433506105526 0.1373775075949518 0.8907324088126172 1.0 0.9638158734839656 11 P78310,Q9HD47,P16615 3 +Chaperone mediated autophagy 0.3486211694170025 0.1347777843562212 0.8927875710671647 1.0 0.965733539121882 9 P13473,Q9NQ11 2 +Negative regulation of camp dependent protein kinase activity 0.3026584867075583 0.1343903895973927 0.8930938806884834 1.0 0.965890797404642 2 P10644 1 +Cellular hyperosmotic response 0.349920453299792 0.1318903952979201 0.895070985703537 1.0 0.967868708741542 7 O95202,P11166,Q9BPX6 3 +Inositol lipid mediated signaling 0.3080012709983354 0.1304959270917606 0.8961740763000159 1.0 0.96890102187587 18 Q05086,O00165 2 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.3282665887167437 0.1285219021834701 0.8977359665201463 1.0 0.9704289434415492 4 P09622,P08559,P11177 3 +Fatty acid beta oxidation using acyl coa oxidase 0.3387646888068889 0.1277966272815156 0.8983099192181845 1.0 0.9708886014331636 5 Q15067,O14734 2 +Cellular senescence 0.3031301420683742 0.1267406847139442 0.8991456437256631 1.0 0.971534818963954 19 O75844 1 +Granulocyte migration 0.3030849648288834 0.1264770605830108 0.8993543062192362 1.0 0.971534818963954 19 Q8N5M9,P35613 2 +Amine metabolic process 0.3242776980840402 0.1246512760776782 0.9007996324930014 1.0 0.9729351424411504 15 Q8N9F7,P21964 2 +Positive regulation of reactive oxygen species metabolic process 0.3413431202339271 0.1215932853625911 0.9032211315340648 1.0 0.9749846810990632 12 P00403,P30536 2 +Protein localization to nuclear envelope 0.3474132296143322 0.1215004844416277 0.90329463101825 1.0 0.9749846810990632 7 Q8NFQ8,Q9BZF1,Q7Z3B4 3 +Neuromuscular process 0.2670043054884422 0.1212426379266717 0.9034988530149576 1.0 0.9750438936157454 26 P04062,P05067,O14773,O75844,P07196 5 +Purine nucleotide catabolic process 0.3408711631026181 0.1194294773864163 0.9049351088406145 1.0 0.9764324612415752 12 P00813 1 +Respiratory gaseous exchange by respiratory system 0.3351884687175369 0.1189048344898148 0.9053507515687766 1.0 0.9767195019403362 13 Q7KZN9,Q9BYC5 2 +Response to thyroid hormone 0.3465925709271633 0.1156277936663385 0.9079475344852086 1.0 0.9791973410076724 6 P04062,O94826,Q9Y376,P48507,Q15648 5 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.3333009798089444 0.1100115085689223 0.912400247798153 1.0 0.9838369371698618 13 Q9H9H4,Q9BRG1,Q9Y3E7,Q92783,O43633 5 +Neural nucleus development 0.3038881498362696 0.1073464856539283 0.9145141073514966 1.0 0.9857151353741468 18 P24539 1 +Neuron cellular homeostasis 0.3430644627539381 0.1068403146368524 0.9149156640456266 1.0 0.9858978961521708 8 Q9UQN3,P20020,P51790 3 +Protein localization to cell surface 0.290763821798432 0.1064898634266747 0.9151936974921916 1.0 0.9860347346474708 21 Q9HD47,Q92544,Q15907,Q9H490,Q92643 5 +Embryonic hemopoiesis 0.3331971339517224 0.1052192203233838 0.916201859765045 1.0 0.9867952055017676 5 Q9H6E4 1 +Regulation of leukocyte proliferation 0.2645122868092402 0.1032268127232676 0.9177829601043346 1.0 0.9883350649226488 26 P30825,P00813,P14174,P60033 4 +Proteolysis 0.2444414649909268 0.1029689413897558 0.9179876210756606 1.0 0.9883924114105084 408 Q6IC98,P04062,Q8NBM8,Q96RU2,Q96A26,Q96A33,Q9Y366,P05067,O43633,Q9HB40,Q4ZIN3,P67812,Q92783,Q6ZXV5,Q969V3,O00560,O94905,O75844,P10619,Q99627,Q9NXS2,Q9UHG3,O75503,Q92896,P52888,Q9NWS0,Q15005,Q9NW81,P46379,Q9H2J4,Q9BXK5,O14773,Q9UJZ1,Q9Y3E7,P22695,P49069,Q9UJX4,Q9Y679,Q92575,P49755,P09622,P28072,Q13619,Q9NZJ7,Q9UJ14,O43292,Q9BXS4,Q15041,Q9UBV2,O00231,Q15392,Q05086,Q9GZP9,Q9NR28,Q16740,P27824,Q9P0J0,Q14118,Q9NWW5,Q6NTF9,O75477,Q9UG56,Q9BUN8,Q9Y3D6,P61289,O95628,P49721,Q96HY6,Q9NZ08,O75787,Q9H300,O76024,Q92542,Q10713,P16435,Q9UBU6,O14737,P42892,Q9BT78,Q9UL46,Q96KC8,Q96FZ2,Q6NXT4,P51572,Q9NQ11,Q8NBM4,Q96CS3,Q92643,Q9UKV5 89 +Regulation of anoikis 0.3430970862998999 0.1017590811940143 0.9189479054681876 1.0 0.9892631805567824 6 P05556,Q07820 2 +Intraciliary transport 0.3406584049010172 0.1007137787879075 0.9197776731011312 1.0 0.9899931821936 9 Q15154,O43805 2 +Positive regulation of glycoprotein metabolic process 0.3410877517073468 0.0987129471020289 0.9213661887752028 1.0 0.991539479117132 8 P62820,Q92542 2 +Lipid storage 0.3060610156479621 0.0980893783405005 0.9218613217087136 1.0 0.9919088030516704 17 P04062,O95674,Q9H6V9,Q14534,P17900,P50416 6 +Hormone transport 0.2639918202357464 0.0973834949313865 0.9224218515615789 1.0 0.9923483597551064 34 Q8N183,O95219,P62820,P51809,Q9BRT2,Q15907,Q16836,Q12846,P50416,Q8N5M9,Q96TA1,Q9UNH7 12 +Regulation of membrane depolarization 0.3405449382148705 0.0964959254667081 0.9231267098332272 1.0 0.9928748179768844 8 Q9HD47 1 +Negative regulation of hormone secretion 0.3411702060288978 0.0961927397375554 0.9233674969267258 1.0 0.9928748179768844 7 Q8N5M9 1 +Negative regulation of peptide secretion 0.3411702060288978 0.0961927397375554 0.9233674969267258 1.0 0.9928748179768844 7 Q8N5M9 1 +Embryonic appendage morphogenesis 0.3355101146127719 0.0952043716213523 0.9241524977102094 1.0 0.9935552544552448 12 Q9NX62,P42892 2 +Skeletal muscle organ development 0.2635179797357069 0.0924335246608762 0.9263536046056472 1.0 0.9955937324441332 28 P60660,P50402 2 +Gamma aminobutyric acid metabolic process 0.292725679228741 0.0920010593231566 0.9266971979447532 1.0 0.9957990630754484 2 O43175 1 +Multi multicellular organism process 0.2633840130908694 0.0914548595391234 0.9271311727323852 1.0 0.9961014311384152 28 Q15363,Q9BQE5,P35613 3 +Regulation of lymphocyte activation 0.2406624181905968 0.0900601185259003 0.9282394411913868 1.0 0.9971280355598772 56 Q08722,P60033,P00813,O96005,P30511,P11279,Q96FZ2 7 +Regulation of glycolytic process 0.3356766256590552 0.0895435257438061 0.9286499639470278 1.0 0.9974048971119116 11 P54646,P54619,P40763,P18669,Q9NQ88,Q13131,P36404,P05067,O15294,O75376 10 +Dna replication synthesis of rna primer 0.305084745762715 0.0888323356883614 0.9292151591052424 1.0 0.997847764211058 3 P49643,P49642 2 +Multicellular organism growth 0.2631129529881776 0.0876513889078589 0.9301537568763598 1.0 0.998691402119881 30 Q15363,O95470,O75844 3 +Regulation of epithelial to mesenchymal transition 0.3382339725938532 0.0845769003106976 0.9325977641343752 1.0 1.0 7 Q14118 1 +Regulation of vasculature development 0.2609093634643881 0.0845277034071338 0.9326368775213868 1.0 1.0 38 P57105,Q86UE4,P09601 3 +Membrane raft organization 0.3373989637289115 0.0837742114984078 0.9332359521696358 1.0 1.0 8 P50897 1 +Dendritic cell migration 0.3273604633994557 0.0822793530754936 0.9344245726013892 1.0 1.0 5 Q4KMQ2 1 +Positive regulation of leukocyte migration 0.3030539949521464 0.0821076852462616 0.9345610818193288 1.0 1.0 17 Q4KMQ2,Q5JRA6,Q08722,P05067 4 +Protein localization to membrane raft 0.316677055876421 0.0817262687590653 0.934864388780571 1.0 1.0 4 Q14254,P05026 2 +Regulation of neurogenesis 0.2361689284953965 0.0815099438576 0.9350364171391664 1.0 1.0 58 Q96G23,P55209,Q9NQC3,Q14118,Q9Y639,P07196,P30536 7 +Action potential 0.276414914082594 0.0766494453102585 0.938902422952608 1.0 1.0 23 Q9HD47,P04062,P16615,P78310,P05023 5 +Blood vessel endothelial cell migration 0.2811771021344837 0.0765430343838646 0.9389870778886624 1.0 1.0 22 P05556,Q16539,P09601,P06576,Q5JRA6,P42785 6 +Carbohydrate derivative catabolic process 0.261084626553837 0.0763457314412052 0.9391440435559072 1.0 1.0 35 P00813,Q13126,Q9NUJ1 3 +Cellular oxidant detoxification 0.2854354182948149 0.074508742292107 0.9406055851614664 1.0 1.0 21 P00374,Q9Y5Z9,Q8TED1,Q99735 4 +Endothelial cell apoptotic process 0.3141276119861483 0.0718571929701876 0.9427155570017044 1.0 1.0 4 Q4KMQ2 1 +Late endosome to lysosome transport 0.3334553901051654 0.071097694584189 0.9433200029847004 1.0 1.0 9 Q9UQN3,Q9Y3E7,O43633 3 +Anterograde dendritic transport 0.3001168907071939 0.0691416419189198 0.9448768748615792 1.0 1.0 3 Q14254,P33176 2 +Production of molecular mediator involved in inflammatory response 0.3293782639357329 0.0683243069386419 0.9455274751986772 1.0 1.0 12 O95219,Q16539,Q8IV08,P51809,Q9UNH7 5 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.3124725538360482 0.066195936542396 0.9472218318502555 1.0 1.0 15 P18031,P46379,O60313,O76024 4 +Regulation of atp dependent activity 0.2601134177448432 0.0650351524184636 0.9481460119042232 1.0 1.0 32 Q96GC9,Q15070,O95433,P09493 4 +Positive regulation of peptidyl tyrosine phosphorylation 0.2956594540942697 0.0625674169495649 0.9501109760693608 1.0 1.0 18 P60033,P14174,O00165 3 +Mononuclear cell migration 0.2585069033752916 0.060882336852829 0.95145291649737 1.0 1.0 26 Q8NHP6,P04062,Q4KMQ2,Q08722,P05067,Q5JRA6,P55011 7 +Osteoclast differentiation 0.3292901993775668 0.0579553045102762 0.9537842304828464 1.0 1.0 10 P60033,Q15904,Q9BRX8 3 +Regulation of leukocyte mediated immunity 0.2578200923695826 0.0555170841800926 0.9557265197322944 1.0 1.0 37 O15400,P60033,P09601,P30511,P11279 5 +Muscle contraction 0.2490766112507153 0.0538927030418456 0.9570206503477584 1.0 1.0 48 Q9HD47,P60660,P00813,P50402,P16615,P09493 6 +Cellular response to calcium ion 0.3255262469755523 0.0519110920489625 0.95859953601682 1.0 1.0 12 Q92542,Q6NUK1 2 +Membrane repolarization 0.3284705178398367 0.051305545056597 0.9590820496096346 1.0 1.0 9 O75844 1 +Regulation of system process 0.2398468356170396 0.04631644827302 0.9630580295519215 1.0 1.0 66 P78310,P04062,Q9HD47,P00813,P05067,P16615,Q14118,P42892,O75844,P05023,P09493,Q6PI78 12 +Embryo implantation 0.3263816895837611 0.046286811446756 0.9630816509841558 1.0 1.0 10 P35613 1 +Metencephalon development 0.2574121349487416 0.0457309827910306 0.9635246689387592 1.0 1.0 30 O14949,Q9BRK5,Q92542,Q96D53 4 +Camera type eye development 0.257368364356512 0.0456550188427599 0.963585216160476 1.0 1.0 34 P54802,P48681,O95140,P08670,Q99471,O75569,P20020,Q8NBN7,Q8NF37,Q99797 10 +Receptor mediated endocytosis 0.2329497278522372 0.0448494355292486 0.9642273208552772 1.0 1.0 58 Q5VW38,Q9NUN5,P27824,P60033,P50897 5 +Cardiac muscle cell proliferation 0.3066820466587263 0.0439588975378348 0.9649371671882708 1.0 1.0 4 P10644,Q16539 2 +Regulation of macrophage chemotaxis 0.3160818713450321 0.0401875972022901 0.9679435656418464 1.0 1.0 5 P28482,Q05397,P14174,P27361 4 +Adaptive immune response 0.2474702260925602 0.0386203276475727 0.9691930952627564 1.0 1.0 48 O15400,P35232,Q03519,P60033,P00813,Q9NZ08,P30511,Q96FZ2 8 +Cardiac muscle cell action potential 0.3007090015398455 0.0384015936561343 0.9693674903669652 1.0 1.0 16 Q9HD47,P16615,P78310,P05023 4 +Branching involved in blood vessel morphogenesis 0.3154970760233957 0.0380887906088544 0.9696168886244748 1.0 1.0 5 Q96T37,Q14344,O14786,Q13043 4 +Natural killer cell mediated immunity 0.3119511377184867 0.0376783982876337 0.969944099433856 1.0 1.0 14 P11279 1 +Positive regulation of peptidyl threonine phosphorylation 0.3255337818075361 0.0360831317668166 0.97121607246914 1.0 1.0 6 Q9C0C2,P61086,P05067,Q9Y376,P28482 5 +Positive regulation of cell activation 0.2481696598720963 0.0347518544603745 0.972277611993956 1.0 1.0 47 P30825,O95219,P49366,Q08722,P60033,P00813,Q12846,P30511,P11279,Q9NRA0,Q14254,P14174,Q96FZ2 13 +T cell receptor signaling pathway 0.274061171811404 0.0339734841937395 0.9728982950393252 1.0 1.0 22 P60033,P49770,P00813,Q9NR50 4 +Antigen receptor mediated signaling pathway 0.274061171811404 0.0339734841937395 0.9728982950393252 1.0 1.0 22 P60033,P49770,P00813,Q9NR50 4 +Regulation of striated muscle contraction 0.3052907650161142 0.0325399095551447 0.97404148964642 1.0 1.0 15 Q9HD47,P16615 2 +Erk1 and erk2 cascade 0.2547710952759976 0.0287992917118373 0.977024665778942 1.0 1.0 36 P35232,P57105,Q99623,P05067,P14174,Q9Y639,Q13641 7 +Nik nf kappab signaling 0.2769295565331741 0.0255715475969449 0.9795990803747716 1.0 1.0 21 Q99623,O43657,P35232,P05067 4 +Regulation of myeloid leukocyte differentiation 0.3216383021447456 0.0251589424190439 0.979928185784066 1.0 1.0 9 Q9BRX8,O00165 2 +Erythrocyte development 0.3209370424597347 0.0250121542859298 0.9800452689239691 1.0 1.0 10 P62753,Q96KR6,Q6NYC1,P18074,O95696,Q9NRK6,Q9NYL9,P11413,Q15648 9 +Negative regulation of notch signaling pathway 0.3116959064327474 0.0246541155532016 0.9803308544277904 1.0 1.0 5 Q96TA1,P31749,Q9NWT6,Q9Y5A9 4 +Small nucleolar ribonucleoprotein complex assembly 0.3105263157894748 0.0205935140936951 0.9835699143737372 1.0 1.0 5 Q9NWS0,Q9Y265,Q9Y230,P55769 4 +Cellular component disassembly 0.2540917329803107 0.020359689837429 0.9837564400289434 1.0 1.0 168 Q96HY6,P04062,P27544,Q99623,Q9H300,P16615,Q9Y2C4,Q9Y6I9,Q01105,O43633,P52789,O95721,P21796,Q96GC9,P12235,P30536,P56962,O00165,P05141,Q13190,Q9NQ11,Q9BWH2,P13473,O75844,Q9Y3D6,O95140,O75381,Q86VR2,Q8N5K1,Q9UEU0 30 +Nls bearing protein import into nucleus 0.3206838299886751 0.0200206137341375 0.9840269284785252 1.0 1.0 8 P52292,Q8NFH5 2 +Humoral immune response 0.3123314481362618 0.0172413955897241 0.9862440381849606 1.0 1.0 13 P60033,Q99623 2 +Regulation of ion transport 0.2460379498875806 0.013681884423534 0.9890837762320306 1.0 1.0 80 Q9HD47,Q4KMQ2,Q99623,P05023,Q15907,P05067,Q9NRA0,O76024,P27105,P21796,Q96GC9,O75844,P14174,Q9UNH7,Q15041,P30536 16 +Negative regulation of atp metabolic process 0.317900627693394 0.0134779423966237 0.9892464834228816 1.0 1.0 10 Q9Y3D6,P30536 2 +Locomotor rhythm 0.2978661210172412 0.012777971411235 0.9898049313292958 1.0 1.0 4 P54802,P42345,O75376 3 +Negative regulation of wnt signaling pathway 0.2659017866331996 0.0123861311610867 0.990117549867201 1.0 1.0 23 P50402,Q9UKV5,Q13641,Q8NBM4 4 +Regulation of synapse structure or activity 0.2526233620477004 0.0122069544221835 0.9902605014127356 1.0 1.0 36 Q05086,P50897,O00264,Q14118,Q13641 5 +Response to wounding 0.2484597617015747 0.0110707884891652 0.991166969221796 1.0 1.0 86 P07196,Q4KMQ2,P49257,P00374,Q99623,P09601,Q96G23,Q9BWH2,P61225,Q5JRA6,Q14118,P09493,P30536 13 +Regulation of myotube differentiation 0.3182217022521103 0.0108419738092101 0.9913495259642257 1.0 1.0 6 Q16539,Q8NEZ5,P42345,Q9BYT8,Q96TA1 5 +Negative regulation of extrinsic apoptotic signaling pathway 0.2656292433202116 0.0107817631828076 0.9913975642855832 1.0 1.0 23 P09601,Q07820,P61289 3 +Cellular response to external stimulus 0.2394798983065068 0.0103390838827883 0.9917507515668508 1.0 1.0 52 Q9Y4P3,P09601,P13473,P21964,Q9Y371 5 +Transport along microtubule 0.2316498580516302 0.0103372135319194 0.9917522438111864 1.0 1.0 57 P62820,O94901,O60313,Q5SNT2,Q9Y366,P05067,O75381,Q15154,P11279,O43805,P07196 11 +Establishment of organelle localization 0.2446213008715812 0.0089799126414704 0.99283516264016 1.0 1.0 136 Q8N6H7,P05556,Q96A57,Q9Y3E7,Q9HCU5,O43633,Q13561,Q99584,Q15363,P62820,P07196,Q9NR31,O95721,P09601,Q96DB5,Q5SNT2,Q15907,P49755,P11279,P20340,Q92783,O00560,O60313,Q15154,Q9NQ11,Q9NRA0,O94901,O75381,Q9UNH7,Q9UH99 30 +Animal organ regeneration 0.2815978799933306 0.008542648996243 0.9931840351589164 1.0 1.0 19 P09601 1 +Nucleobase containing compound transport 0.250682637507123 0.0074543460066816 0.9940523474929104 1.0 1.0 111 Q15388,O43808,Q08722,Q9HC21,P05141,P12236,L0R6Q1,Q9H2D1,Q8TB61,O00400,P41208,Q6NUK1,P12235,Q9BSK2 14 +Cellular response to virus 0.2503822886950996 0.0062177587069007 0.995038978290936 1.0 1.0 26 Q99623,O43657,O60443 3 +Protein deneddylation 0.3164906841209625 0.0050983268999137 0.9959321413032398 1.0 1.0 8 Q9BT78 1 +Regulation of cytokinesis 0.2770224882804889 0.0042529553503316 0.9966066428178206 1.0 1.0 20 P41208 1 +Macrophage chemotaxis 0.3161743199765909 0.0040077976803242 0.996802248668666 1.0 1.0 6 P27361,P28482,P14174,Q9BW27,Q05397 5 +Negative regulation of cytokine production 0.2516253485942092 0.0034482378819249 0.997248709684336 1.0 1.0 31 P30511,Q9Y639,P09601,P30536 4 +Centromeric sister chromatid cohesion 0.3155893536121593 0.0020742464057021 0.9983449920043675 1.0 1.0 6 P41227,Q9GZZ1,O60566,P49711,P30153 5 +Positive regulation of reproductive process 0.3156816851960247 0.0019744312741859 0.9984246327935238 1.0 1.0 7 Q07021,P30307,Q9H6S0,Q8IY37,O14965,Q92769 6 +B cell activation 0.2503205706772846 0.0018641536033902 0.998512621482347 1.0 1.0 39 P35232,P60033,P05141,Q99623,P00813,P55327,Q96FZ2 7 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c642a54fd6933d271024c446af348b69950dbed3 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aorta smooth muscle tissue morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "Bundle of his cell to purkinje myocyte signaling", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp catabolic process", "Camp mediated signaling", "Camp metabolic process", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell cytokine production", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate commitment involved in pattern specification", "Cell fate determination", "Cell fate specification", "Cell fate specification involved in pattern specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cholesterol", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex gabaergic interneuron development", "Cerebral cortex gabaergic interneuron differentiation", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of stimulus involved in sensory perception of pain", "Detection of temperature stimulus", "Detection of temperature stimulus involved in sensory perception", "Detection of temperature stimulus involved in sensory perception of pain", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial cilium movement involved in determination of left right asymmetry", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose catabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Gabaergic neuron differentiation", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological memory process", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learning", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens fiber cell morphogenesis", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene d4 metabolic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage fusion", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast fusion involved in skeletal muscle regeneration", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "Myotube differentiation involved in skeletal muscle regeneration", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Nail development", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell cytokine production", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell cytokine production", "Negative regulation of t cell differentiation", "Negative regulation of t cell mediated immunity", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural fold formation", "Neural nucleus development", "Neural plate development", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation cycle", "Ovulation cycle process", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine acyl chain remodeling", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transmembrane transport", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell differentiation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd4 positive alpha beta t cell proliferation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion mediated by integrin", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix constituent secretion", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper 2 cell cytokine production", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type 2 immune response", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to site of double strand break", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sulfation", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor mediated virion attachment to host cell", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell differentiation", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix constituent secretion", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron maturation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to inactivity", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle inactivity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to stimulus involved in regulation of muscle adaptation", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Sa node cell to atrial cardiac muscle cell communication", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of temperature stimulus", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Smoothened signaling pathway involved in ventral spinal cord patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron cell fate specification", "Spinal cord motor neuron differentiation", "Spinal cord patterning", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell cytokine production", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tonic smooth muscle contraction", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventral spinal cord interneuron differentiation", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD13", "ABHD16A", "ABHD6", "ABI2", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG5", "ALG6", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf57", "C12orf73", "C19orf70", "C1QBP", "C2orf49", "CAB39", "CABLES1", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CD81", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPH", "CENPI", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "CNTLN", "COA1", "COA3", "COASY", "COG4", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1C", "CORO7", "COTL1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRCP", "CRK", "CRKL", "CRMP1", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTB", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GJC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPX8", "GRAMD4", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IBTK", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPA1", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS4", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1211", "KIAA1468", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRWD1", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LYSMD3", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED17", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL16", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS2", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NENF", "NES", "NFATC2IP", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OFD1", "OGDH", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACS1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PAXIP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX11A", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTMA", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAI", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F1", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUFU", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTC7B", "TTF1", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TXNRD2", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCR11", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URGCP", "UROD", "USO1", "USP10", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UST", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AASDHPPT", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCD3", "ABHD10", "ABHD12", "ACAP2", "ACAT2", "ACBD5", "ACOT8", "ACOX1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ADA", "ADD1", "ADI1", "ADPGK", "AFG3L2", "AGK", "AGPAT5", "AGPS", "AGTRAP", "AHSA1", "AIFM1", "AK3", "AKT1", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ALG5", "AMFR", "ANAPC5", "ANKLE2", "ANO6", "ANXA1", "ANXA3", "APOL2", "APOO", "APOOL", "APP", "ARF4", "ARFGAP2", "ARG2", "ARL1", "ARL2", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ARMCX3", "ASAH1", "ASNA1", "ASPH", "ATAD1", "ATAD3A", "ATAD3B", "ATG13", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP6V1E1", "ATP7B", "ATPIF1", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BAG4", "BAG6", "BAK1", "BANF1", "BCAP29", "BCAP31", "BCL2L13", "BCS1L", "BET1", "BNIP1", "BRD1", "BSG", "BUB1B", "C12orf73", "C19orf70", "C1QBP", "CAB39", "CAMLG", "CANT1", "CANX", "CASK", "CCAR2", "CCDC134", "CCDC47", "CCDC51", "CCNB2", "CD47", "CD81", "CDC25C", "CDC37", "CDIPT", "CDK2", "CDK4", "CDK9", "CDS2", "CERS1", "CERS2", "CETN2", "CHCHD3", "CHID1", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHPF2", "CHST14", "CISD1", "CISD2", "CIZ1", "CLCC1", "CLCN3", "CLN5", "CLN6", "CLPP", "CLPTM1", "CLPTM1L", "CLUH", "CNNM3", "CNOT4", "CNPY2", "COA1", "COA3", "COG4", "COMT", "COPS2", "COPS4", "COPS8", "COQ8A", "COQ8B", "COQ9", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "CPT1A", "CPT2", "CRTAP", "CTCF", "CTSA", "CTSC", "CUL4A", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAG1", "DAGLB", "DCAKD", "DCPS", "DCTN2", "DCTPP1", "DDRGK1", "DDX5", "DERL1", "DERL2", "DHCR24", "DHFR", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHX37", "DHX8", "DIABLO", "DICER1", "DLD", "DMAC2", "DNAJC1", "DNAJC19", "DOHH", "DOLPP1", "DPF2", "DPM1", "EBP", "ECE1", "ECSIT", "EEF1E1", "EI24", "EIF2B2", "EIF2B3", "ELMO2", "ELMOD2", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "ENOPH1", "EPDR1", "EPPK1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ESYT1", "ESYT2", "EXOC1", "EXOC2", "EXOC3", "EXOC7", "EXOC8", "EXOG", "EXOSC3", "EXOSC5", "EXOSC6", "EXT2", "EZR", "FADS2", "FAF2", "FAM129B", "FAM162A", "FAM210B", "FAM213A", "FAM8A1", "FBXO22", "FCGRT", "FDFT1", "FECH", "FGFR1OP", "FIS1", "FLOT2", "FOXRED1", "FUCA1", "FUNDC2", "FUT8", "G6PD", "GAA", "GALNT1", "GALNT2", "GBA", "GCLM", "GDAP1", "GDPD1", "GGT7", "GHITM", "GINS2", "GINS4", "GJC1", "GLA", "GLB1", "GLG1", "GLTP", "GM2A", "GMPS", "GNA11", "GNA13", "GNPAT", "GOLGA5", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GPAA1", "GPAT4", "GPD2", "GPR107", "GPX8", "GRAMD4", "GSDME", "GSK3A", "GSTO1", "GSTZ1", "GXYLT1", "HACD2", "HACD3", "HADH", "HAX1", "HCCS", "HDAC2", "HEATR3", "HIF1AN", "HIGD1A", "HK2", "HLA-A", "HLA-C", "HLA-F", "HM13", "HMCES", "HMGB1", "HMOX1", "HMOX2", "HNRNPK", "HOOK2", "HPS6", "HS2ST1", "HSD17B11", "HSD17B12", "HSPA13", "HTATIP2", "HTRA2", "ICMT", "IER3IP1", "IFT52", "ILVBL", "IMMT", "IMPAD1", "INA", "IPO4", "IRF2BP2", "IST1", "ITGB1", "ITM2C", "ITPRIP", "JAGN1", "JMJD6", "KDELR1", "KIAA1468", "KIF20A", "KIF3A", "KIF5B", "KLC1", "KPNA2", "LAMP1", "LAMP2", "LAMTOR1", "LBR", "LCLAT1", "LDAH", "LEMD3", "LETM1", "LMAN1", "LMBRD1", "LMNA", "LPCAT1", "LPCAT4", "LPGAT1", "LRP1", "LRPAP1", "LRRC59", "LYSMD3", "MAGT1", "MAIP1", "MAN1A2", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MAU2", "MAVS", "MBLAC2", "MBOAT7", "MCAM", "MCCC2", "MCL1", "MCM2", "MCM6", "MCM7", "MCUB", "MCUR1", "MED1", "MFN1", "MFN2", "MFSD10", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MIPEP", "MMGT1", "MOSPD2", "MPP1", "MPV17L2", "MRC2", "MSH2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "MTX2", "MTX3", "MYL6", "NAA10", "NAA50", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NCLN", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA3", "NDUFA6", "NDUFAF1", "NDUFAF2", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NEFL", "NES", "NLN", "NNT", "NOVA2", "NPC1", "NPTN", "NRP1", "NSD2", "NSDHL", "NUCB2", "NUCKS1", "NUDT12", "NUDT16L1", "NUDT9", "NUP35", "NUP54", "NUP85", "NUP93", "OCIAD1", "OCLN", "OFD1", "OGT", "OLA1", "OPA1", "OPA3", "OSBPL3", "OSBPL6", "OSBPL8", "OXA1L", "P3H4", "P4HA1", "P4HA2", "P4HB", "PAIP2", "PARL", "PAWR", "PCBD1", "PCK2", "PCM1", "PCYOX1", "PCYOX1L", "PDCD5", "PDCL3", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDZD11", "PECR", "PEX11A", "PEX14", "PEX19", "PEX3", "PFDN5", "PGAM1", "PGRMC1", "PGRMC2", "PHB", "PHB2", "PHGDH", "PI4K2A", "PIGK", "PIGL", "PIGS", "PIGU", "PIH1D1", "PISD", "PITRM1", "PLBD2", "PLD3", "PLIN3", "PMPCA", "POLDIP2", "POMGNT2", "PON2", "POR", "PPM1L", "PPP2R1A", "PPT1", "PPT2", "PRAF2", "PRCP", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKRA", "PRPF31", "PSAP", "PSMB2", "PSMB6", "PSMC3", "PSMD11", "PSME2", "PSME3", "PTGES2", "PTK2", "PTK7", "PTPN1", "PTPRF", "PUF60", "PXMP2", "QPCTL", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RANGRF", "RAP2B", "RBM15", "RDH11", "RDH13", "REEP3", "REEP4", "REEP5", "REEP6", "RER1", "RETREG3", "RETSAT", "REXO2", "RFT1", "RHBDD2", "RIDA", "RMDN1", "RPRD1B", "RPS3", "RPS6", "RPUSD3", "RTN2", "RTN3", "RTN4", "RUVBL1", "RUVBL2", "S100A13", "SACM1L", "SAMM50", "SAR1A", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCO1", "SCO2", "SCP2", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC22B", "SEC61B", "SEC62", "SEC63", "SEL1L", "SET", "SETD3", "SF1", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3GLB1", "SLC12A2", "SLC12A9", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLU7", "SNAP29", "SNU13", "SNW1", "SNX2", "SNX30", "SNX4", "SNX5", "SNX6", "SOAT1", "SORT1", "SPCS2", "SPHK2", "SPTLC1", "SQLE", "SRP9", "SRPRB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSU72", "STAM", "STAT3", "STK4", "STOM", "STOML2", "STT3A", "STT3B", "STX10", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUN1", "SUN2", "SURF4", "SYAP1", "SYNGR2", "SYNJ2BP", "TAF6L", "TAMM41", "TAP1", "TAP2", "TBC1D10A", "TBC1D8B", "TBL2", "TCP1", "TDRKH", "TEX264", "TFIP11", "THOP1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP2", "TLCD1", "TM7SF2", "TM9SF1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMOD3", "TMTC3", "TMX1", "TNKS1BP1", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOR1AIP2", "TOR1B", "TPBG", "TPD52", "TPM1", "TPP1", "TPR", "TRAM1", "TRIM25", "TRIP13", "TRMT112", "TSNAX", "TSPAN6", "TSPO", "TTC19", "TTYH3", "TUBB2B", "TUBGCP6", "TXNDC12", 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9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 9.607627715673584e-22 0.0005428611587646 8.122334253643087e-07 4.122356832379468e-12 2.354651365736154e-24 +Golgi membrane 73 153 5.243317108197556 1.57715135688287e-07 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 1.0223084486650402e-12 0.1463513896823768 0.0075465906671422 0.0002568676230629 2.762799264992253e-15 +Outer membrane 46 99 4.96061687304423 7.026966702515868e-07 28.936893203883496 87.79611650485437 1.4859238244628277 0.3236686433663402 11.632349354832256 8.24751710010496 1.9336855473946637 0.38878066573106 1.4417864464946895e-16 2.046430492147924e-06 1.5492381445016576e-10 1.8064286961635672e-13 6.396722885197977e-18 +Mitochondrial protein containing complex 81 177 4.948164954663133 7.491640869537029e-07 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 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3.3601842163433866 1.8185871159494191 0.3070405082296492 2.5125849992146505e-18 9.216009865795702e-05 7.631546446868991e-06 1.1558370428008e-10 6.3841488203070295e-19 +Endoplasmic reticulum golgi intermediate compartment 25 59 4.22800061565381 2.357771470640202e-05 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 3.0160780787381053e-10 0.080392228927645 0.0145704521374391 4.012843376694993e-06 3.899110619300651e-12 +Endoplasmic reticulum golgi intermediate compartment membrane 25 32 4.091600138400022 4.284068805526786e-05 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 1.4238881374298635e-11 0.2333020504203794 0.0157478410048603 6.510996256619785e-07 3.0576635968340034e-14 +Endoplasmic reticulum protein containing complex 28 71 3.7562881201993794 0.0001724521442432 20.067961165048544 61.213592233009706 0.544324442160867 0.4875881372361492 7.672624563199495 5.300944201362535 1.5348103009085623 0.3893079894443684 5.816384558683572e-11 0.0948632313276182 0.0855550276988868 0.0012066818666679 3.938101222010811e-11 +Microbody membrane 16 28 3.714556189803482 0.0002035606362911 9.83980582524272 26.8373786407767 1.0322166739723002 0.3740701224912098 5.101262737371427 4.075770333088885 1.3138416014090577 0.3534887732287703 0.0009632698194349 0.2406936845278361 0.4242240140575919 0.1596086760652474 0.0003655904724143 +Transporter complex 31 67 3.687166052266139 0.0002267653919585 16.033980582524272 55.199029126213595 0.256193630237002 0.358562058071074 7.704418772430675 7.665912382074106 1.666161547187811 0.3440522205931707 3.025291184939518e-06 0.0339714602069511 0.0005411829706675 1.3599145600633182e-05 3.9997142580987015e-08 +Secretory granule membrane 36 74 3.525164714804032 0.0004232195486879 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 6.9734555552280704e-06 0.5851156872439878 0.2522992371519743 0.0319784316416502 2.0623701868059167e-06 +Golgi cisterna 15 28 3.4912232210462237 0.0004808143561398 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 2.049313522693913e-05 0.297366720714231 0.1554832015057707 0.0317341418138132 8.850050427314066e-06 +Intrinsic component of plasma membrane 54 86 3.4691013367559065 0.0005222024435946 29.711165048543688 79.49271844660194 0.9914207279546418 0.2992612012372248 13.467745416506318 12.62980929789956 2.1277799030157807 0.3627370007757806 0.3694319127136964 0.9000303444062265 0.8330259814094686 0.9399265719751224 0.1023154362324898 +Copii coated er to golgi transport vesicle 19 40 3.38296858951881 0.000717068330702 10.810679611650484 32.4247572815534 0.9209697551014924 0.3949407296339237 5.01338814607213 3.9617918728777735 1.2509556054930144 0.3456813773327062 3.236590971932772e-08 0.2766173679843171 0.1355867800667393 0.0002009923531869 1.690333216925589e-09 +Cytochrome complex 12 19 3.3755096895924326 0.000736790975123 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 3.049332835878312e-07 0.000349084453734 2.684369985471731e-07 2.927092645951376e-07 3.661800299111565e-09 +Azurophil granule membrane 13 23 3.3593062871792743 0.0007813841134056 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 6.191659038085216e-07 1.0 1.0 0.0247625444605767 1.287772595613843e-06 +Transport vesicle 34 102 3.3123671079372787 0.0009251006529027 26.046116504854368 92.34708737864078 0.9512017428916244 0.4458616213657612 9.46815354334768 9.09007867686459 1.424803887648301 0.3967491654773343 0.0003250935611405 0.3582794844835456 0.2423406323390604 0.1025200434297228 9.499492155615844e-06 +Outer mitochondrial membrane protein complex 13 17 3.24507224206806 0.0011742083070995 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 1.7059212416589812e-10 0.0001122733832082 1.0236679094826864e-06 1.0378820679868198e-08 4.049640390482079e-13 +Oxidoreductase complex 29 71 3.1867677949509736 0.0014387223036769 16.138349514563107 58.1747572815534 0.4112275970760134 0.4385210691837483 8.292749505639035 5.03902669070441 1.4297411393453454 0.366860872580609 6.193435050857891e-07 0.0014161110284603 5.353855778852642e-05 3.439255636365252e-05 1.3930644143363416e-08 +Snare complex 12 21 3.171714967323941 0.0015154166416946 6.20873786407767 15.79368932038835 0.8138466711937282 0.3737991711938105 3.1112263618988054 3.010283181947674 1.1802712183474584 0.3261149602927671 0.0001059730540048 0.187449079081247 0.0080456420559546 0.0036383017284534 6.816187763012859e-08 +Golgi stack 15 36 3.1440966293916977 0.001666004172389 9.67233009708738 31.25242718446602 0.7055900861920908 0.4265468940333196 4.557817503574521 5.847941213698429 1.2226912303929196 0.3463938041520717 0.0004550374648143 0.377722993581858 0.2426635790855314 0.089202410661812 0.0002563222355264 +Nuclear inner membrane 14 23 3.044642114447419 0.0023295733955146 7.347087378640777 20.57281553398058 1.3204335588742686 0.2519451141048848 3.6006224195129035 1.9968516080603145 1.2188770932171689 0.2896682474252494 8.724031221876497e-05 1.0 0.3339976348230559 5.880242055622103e-05 2.3975686123427828e-05 +Coated vesicle 29 101 3.038391213206716 0.002378449626428 21.15776699029126 89.28398058252426 0.7996411773181966 0.4463095457932411 7.252509633536616 8.542551157088123 1.3406722753228342 0.3892656029628454 4.1168790746384e-06 0.6239158458722325 0.3045959264313371 0.0003754682240757 4.203034756985093e-07 +Autophagosome membrane 11 19 3.0261071171849063 0.0024772452558987 4.174757281553398 13.37135922330097 -0.0098942360451326 0.445924723627937 2.326200220393679 3.0901432865083773 1.1383635180898088 0.3067757682348186 0.000702077694251 1.0 1.0 0.0901467992310857 0.0002155385692345 +Exocytic vesicle 21 43 3.0221560879536056 0.0025098109484809 12.106796116504857 38.40533980582524 0.7408080162244459 0.4227017753873355 4.952517495270036 4.6543925000719675 1.3317240485888555 0.365166844745196 0.008658565506817 0.4829170776296618 0.3769506193807974 0.4196721024576437 0.006225493443807 +Proton transporting two sector atpase complex 14 24 2.9406502800159204 0.0032752408359815 7.116504854368932 22.25728155339806 1.0735578367707936 0.2848832687688338 3.2910616544032156 1.9833825153714253 1.32099194967518 0.2987458873835026 0.0006944570176906 0.151306852499084 0.0041517217414646 0.0012549484261259 0.0001729005795719 +Intrinsic component of golgi membrane 11 14 2.9215213894447456 0.0034832635682382 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 1.3167572375235434e-05 0.1835089509173778 0.0614247268920475 0.0032788281256578 3.434320745486082e-06 +Respiratory chain complex iv 5 11 2.840797440038504 0.0045000885806552 3.754854368932039 9.74271844660194 0.8119042784517004 0.2590637228606872 2.032646352020888 1.0643473720992946 1.3870085883810457 0.2875864020654643 9.760476704961712e-05 0.0032958763634803 2.214575962840231e-05 5.302129833761715e-05 0.0001429815632908 +Lipid droplet 13 30 2.8243741893356944 0.0047373042478691 7.313106796116505 30.72087378640777 0.9597061621709796 0.3916106255858687 3.663189105886808 2.181620314734523 1.1934081113966928 0.3497541884861006 0.0027662762877035 1.0 1.0 0.2146915796551673 0.0012083889035143 +Endoplasmic reticulum lumen 30 67 2.8110837001463 0.0049374939600372 18.07766990291262 59.737864077669904 0.9896277047863468 0.3946249358858228 7.513340007333169 6.273245958458151 1.4320597420402308 0.3846324865730224 0.0212739538759727 1.0 0.807157783628021 0.2266833636016097 0.0354444379817602 +Nadh dehydrogenase complex 16 31 2.810409838793295 0.0049478449737576 7.419902912621359 23.609223300970875 0.690247022635013 0.3818090321561181 3.6908298840900926 3.1049932192976284 1.21822710313397 0.3228613418826432 2.5262095056170573e-05 0.0196403757049561 0.0008840144918394 0.0007016746800212 7.133480197010416e-06 +Micos complex 4 5 2.8078847977578523 0.0049868062697708 2.4927184466019416 4.725728155339806 0.7557668283408772 0.3464970141803932 1.2077602589329477 0.4877312285913208 1.1862461875397572 0.3249829583805667 0.0002518200710585 0.0378187125466048 0.002465796513642 0.0007187465088185 1.3106068439724131e-05 +Vacuolar membrane 46 134 2.7753070710886973 0.0055149609412969 31.91504854368932 121.20631067961163 0.8693310080509177 0.3422944242486927 10.598363436017626 13.850227259030053 1.9844114292962869 0.3837860427998523 0.0014111980887469 1.0 0.9634798552008634 0.3007236877491425 9.2803861434833e-05 +Tim23 mitochondrial import inner membrane translocase complex 5 7 2.710593141615833 0.0067162982138113 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 3.1885773516610338e-06 0.0012105019492812 0.0047533286028597 9.701143498590324e-05 4.765057901286244e-06 +Autophagosome 15 30 2.6847894505165497 0.0072575510148769 7.490291262135922 28.23058252427185 0.2382857558920592 0.551676712271876 3.4770262532301657 5.388565442188036 0.9533210099421008 0.3228297396792804 0.0092258961829589 0.3624074851394556 0.2248900268904883 0.0750173773780456 0.0052453150917069 +Intrinsic component of mitochondrial outer membrane 8 15 2.67206027630284 0.0075387105572717 5.004854368932039 12.186893203883496 0.537559322132711 0.4142348023165385 2.5976045215999015 2.144426747635188 1.2224430201503769 0.3320793466689031 0.0004374409320435 1.0 0.0202898922491691 0.0173886328284286 7.490488694519441e-06 +Golgi cisterna membrane 11 20 2.642528603144454 0.0082289514417772 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 0.0004813667994859 1.0 0.3955810682553247 0.1312000588255236 0.0007920809146458 +Endoplasmic reticulum tubular network 6 11 2.638740169423874 0.008321473324317 4.456310679611651 11.402912621359222 0.7597390036291544 0.4204688348420043 2.5600618129260964 1.9933849978482647 1.110800197793671 0.3406591463359876 3.5302578715998566e-05 1.0 0.018640880521655 1.0246004736236846e-05 5.493155547881244e-05 +Gpi anchor transamidase complex 3 5 2.625327614759471 0.0086565630507347 1.7281553398058251 4.050970873786408 0.3650490188514708 0.4588417110466823 1.1121061515765476 1.035685612757101 1.021268150080817 0.3062595682607533 0.0008632397286687 1.0 1.0 0.1154193350298319 0.0010568895936515 +Transport vesicle membrane 16 47 2.622269304511672 0.0087346380269097 12.62135922330097 42.37378640776699 0.5402420874587609 0.5343084089707166 5.404271063272784 4.511161156897919 1.052801184280702 0.3556606283757049 0.0139696543895272 1.0 0.7145877024539901 0.203263672897995 0.0014382286873073 +Mitochondria associated endoplasmic reticulum membrane 7 10 2.6180049180223444 0.0088445530392737 4.191747572815534 9.240291262135925 0.7019541594808174 0.4009163152547425 2.0831338076447135 1.0418560326821893 1.1194321867771957 0.3336055532093068 7.716967519913913e-06 1.0 1.0 0.0007869115437374 8.294870660489475e-07 +Golgi medial cisterna 2 5 2.594149802599137 0.0094825160584666 1.4902912621359223 3.4733009708737863 0.7236971844675457 0.3405036808602053 1.1266424526606664 1.239231588055279 1.2311376953203692 0.3093903079022938 0.0116152577017657 0.0516364610584135 0.1008375048293403 0.027832231049335 0.0140126286640228 +Mitochondrial proton transporting atp synthase complex coupling factor f o 2 5 2.588346782388573 0.0096437839001861 1.9733009708737863 5.242718446601942 0.4211347050302871 0.333781611012728 1.3226062005917398 0.5065784601240608 1.2214331629505923 0.2724252877078135 0.0028218227860889 1.0 0.0653907127050202 0.0113265963942617 0.0034377129995212 +Phagocytic vesicle membrane 13 27 2.583336299201186 0.0097849890777503 7.512135922330097 23.83009708737864 0.5348434256443761 0.4468744105904624 3.681144332021715 3.0024693704800938 1.1652764437248655 0.3385441964418395 0.0197681847521206 1.0 1.0 0.4371334046337463 0.000641595952047 +Proton transporting atp synthase complex coupling factor f o 3 7 2.582185168693784 0.0098176893120967 2.388349514563106 6.79126213592233 0.5842994650422648 0.284211882186535 1.5103719705721683 0.8950355849210965 1.3255228108854136 0.2674401609228611 0.0007024718324135 0.0470522829573702 0.0039135152062846 0.001485709034831 0.0009118158302113 +Vesicle membrane 87 270 2.581305366354965 0.0098427475287572 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 0.0007636190251558 0.8934297385951826 0.4618570263014726 0.2366254257434301 8.115019604315393e-05 +Mib complex 9 11 2.5648450808923937 0.010322188059292 4.669902912621359 10.016990291262136 0.8674199579421746 0.3102009046029466 2.3929035436504367 0.6011337749949848 1.2568635951567688 0.31203902687269 5.074023283755038e-07 0.0017062060788896 0.0002296483500821 8.796898694645245e-06 3.028938715404879e-08 +Organelle membrane contact site 9 16 2.5596424494829333 0.0104779904042535 6.817961165048544 16.400485436893202 0.815819301321945 0.3904411977369264 3.451940177462974 2.047328298639296 1.2919706717077657 0.3464717655445403 1.832875539522981e-05 0.1553991536419083 0.2872333566147377 0.001435579094649 4.065628476628564e-06 +Hrd1p ubiquitin ligase erad l complex 3 5 2.539364045767723 0.0111054198432529 1.5922330097087378 3.79126213592233 0.7277489081729471 0.3220832800800837 1.0445131090737272 0.9111612984907131 1.2162191074948896 0.2849748010669527 0.0001305835606601 1.0 1.0 0.1577810442013011 0.0001708540892308 +Respiratory chain complex iii 6 9 2.531286136871495 0.011364509732338 2.5145631067961167 7.186893203883495 0.8648567981956616 0.2640480169416735 1.5224155414895728 0.9433070612984726 1.3007640218760226 0.2795290338624424 0.0021455018963906 0.0607401038440192 0.0066572828402184 0.0002022933287296 1.6279070379868977e-05 +Er ubiquitin ligase complex 5 6 2.4393763840443703 0.0147126353825655 2.0970873786407767 4.70873786407767 0.8764155338390741 0.2924583478733635 1.3110031963021629 1.3573322490080977 1.246637632205364 0.2924172085124771 3.8987794627620416e-05 1.0 1.0 0.2175647207167039 5.436360967141595e-05 +Proton transporting atp synthase complex 4 12 2.399382530785971 0.0164227482155736 4.157766990291262 11.08495145631068 0.5328143574617974 0.3012358599713604 2.3610641964760792 1.138499586439592 1.3748267965121657 0.2836171984539964 0.0007350148232219 0.0786913117950012 0.0113213926532688 0.00062382482254 0.0010053263520343 +Golgi apparatus subcompartment 28 101 2.3800809366889237 0.0173088358521076 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 0.0124388722832277 0.379151373575087 0.2676537229472664 0.2176268781816471 0.001686917975415 +Emc complex 4 7 2.361980230671638 0.0181776115252318 1.9635922330097089 5.686893203883495 0.4346685280287892 0.4212908647152366 1.4128861560779629 1.136987613501037 1.0888942312003185 0.31377177158709 0.0007024718324135 0.0470522829573702 0.0921025797166938 0.0231366382468947 0.0009118158302113 +Specific granule membrane 10 18 2.3599278156531023 0.0182784913482256 4.703883495145631 15.434466019417476 0.8701513897757543 0.3699585460258285 2.477017558764293 2.6655071934549124 0.9998631482292508 0.308737972868479 0.1805888683807864 0.2107016729382093 0.0803922289273931 0.0304079267330467 0.2132278663521486 +Proton transporting two sector atpase complex proton transporting domain 7 11 2.357461467925855 0.0184003648065715 4.053398058252427 10.283980582524272 1.020958321179617 0.2307004649223604 1.8491832641634656 1.1862626633334956 1.3576055733210162 0.273185751006507 0.0003845948196129 0.0697581245313758 0.0088504827764808 0.0051503840765812 4.367834065541858e-05 +Intrinsic component of peroxisomal membrane 4 7 2.3344066582382665 0.0195744384820855 1.9320388349514563 4.434466019417476 0.5069121698582412 0.444591863161664 1.4960279832433574 1.753796563107492 1.0627811042818465 0.325067944975853 0.0280038679646325 1.0 1.0 0.307957256786686 0.0334620993119388 +Er to golgi transport vesicle membrane 10 25 2.320674839225944 0.0203043996657512 6.495145631067961 21.890776699029125 0.3958870084748403 0.5141628679854253 3.1618901389258056 2.1225127942575894 0.9657155478739712 0.3164691847513972 0.000702077694251 1.0 1.0 0.0901467992310857 3.704127201812019e-05 +Recycling endosome 16 43 2.306710501764113 0.0210709644118125 11.66504854368932 38.48300970873787 0.3314123370484901 0.5655153978404952 4.733627044629046 5.712973030267684 1.060328776827888 0.3489425897551162 0.2114801995318231 0.5051564551774747 0.7559683387594784 0.6868769056891976 0.0944921409351227 +Prefoldin complex 2 6 2.302337450046443 0.0213161494252531 2.0 4.558252427184466 0.6613596346898009 0.3787606197734878 1.2637592249478444 0.939430138341434 1.0491603610968223 0.3009247811837955 0.2772499461070952 1.0 1.0 1.0 0.2942334307578267 +Lysosomal lumen 17 37 2.276241902164662 0.0228315352554571 18.075242718446603 34.54368932038835 0.7848519845050315 0.1014568164283454 6.206531846566726 3.2976210873168883 3.038689298289951 0.2012423645269794 0.0002164854419953 1.0 1.0 0.0059425292278447 1.9164937388887257e-05 +Organelle envelope lumen 21 44 2.259121030801542 0.023875857274316 11.436893203883496 36.55339805825243 0.6276066761486734 0.4428242266058088 4.702137301503097 3.7796803567009714 1.1382138566471218 0.3469405856623805 0.0091795354188294 1.0 0.5351022899588459 0.0121231126733016 0.0047064147832106 +Cis golgi network 6 15 2.192187049822112 0.0283660031633132 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.007660250712326 0.1715759324473242 0.0538434207197609 0.0023536569339089 0.0105883475769395 +Phagocytic vesicle 17 44 2.181795049125034 0.0291246621394096 11.54126213592233 41.59708737864078 0.3919256884663005 0.5681630099638236 4.854259100699266 4.0100348958770144 0.9938295058309184 0.3509625084864278 0.0371800949410908 1.0 1.0 0.7016658504359256 0.0003176274883727 +Derlin 1 retrotranslocation complex 2 5 2.165600913016175 0.0303416965652583 1.546116504854369 4.077669902912621 0.5843752329685453 0.3810058843239468 0.9605365945831608 0.5777310891965762 1.1710090741207233 0.3200150910339656 0.0478482703534769 1.0 1.0 0.1781979724676324 0.0542215392640632 +Intrinsic component of nuclear inner membrane 5 7 2.140736233190317 0.0322953148317326 2.4344660194174756 6.461165048543689 0.7221555748366164 0.3746407047127702 1.5973511010756076 0.8763043548183138 1.0289148549650529 0.2984963891905157 0.0028218227860889 1.0 1.0 0.0113265963942617 0.0001708540892308 +Integral component of synaptic vesicle membrane 4 6 2.135876408370044 0.032689489003963 2.2475728155339807 4.910194174757281 0.8567274645780141 0.3149754325120096 1.3818760752746044 1.4445051429216968 1.1133243513780926 0.2989777184888048 0.1784863028688835 1.0 0.1515272625734178 0.3411306657380243 0.0465653262864464 +Azurophil granule 21 69 2.121042911167152 0.0339181914605075 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 5.794244280829937e-05 1.0 1.0 0.146718557832825 0.0001303770760705 +Protein lipid complex 1 5 2.1200693704256564 0.0340001955638507 0.9733009708737864 4.152912621359223 0.8806614337674874 0.2932450111231078 0.8822773800999041 1.1227636940840768 1.0732388951245535 0.2459144485958364 0.1620941907570236 1.0 0.1432798584585485 0.0561137872346343 0.1807018090276839 +Nucleotide excision repair complex 0 5 2.117491556607408 0.0342181511368853 1.5533980582524272 4.934466019417476 0.2841448149228163 0.5542842134362547 1.31811983882756 0.9100711891020776 0.8468277475661165 0.3060785085592118 0.3997040719021639 0.0516364610584135 0.1008375048293403 0.2365379696877526 0.4217257773445009 +Ciliary membrane 1 7 2.1083740807439737 0.0349986446076167 1.75 5.242718446601942 0.2339004145089494 0.6313496889667123 1.3467418432027014 1.125313500374781 0.7031395182425678 0.2857575503177525 0.4290564413347806 0.1430638950507344 0.266209970857853 0.544318157098314 0.4647244871500471 +Synaptic vesicle membrane 8 16 2.096618305385147 0.0360273775191875 5.099514563106796 14.07766990291262 0.7734258277348643 0.4227625879426745 2.579286376297321 2.2325453295101236 1.0485572818049853 0.3297289695807819 0.2986062515589491 1.0 0.4461675288226883 0.4371334046337463 0.1733847659071939 +Pore complex 5 10 2.072389012141724 0.038229177243414 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0007350148232219 0.0029386578360865 0.0005309775927247 0.00062382482254 9.937036022358197e-05 +Myofilament 4 5 2.033745948590424 0.0419772167940748 2.174757281553398 4.186893203883495 0.404875148061941 0.4374833583964219 1.241883821669583 1.0388207738802084 1.088024284468753 0.3207832055944606 0.3711832246405026 1.0 1.0 1.0 0.3921885014959403 +Striated muscle thin filament 4 5 2.033745948590424 0.0419772167940748 2.0776699029126213 4.036407766990291 0.3903791791430543 0.4433177448944362 1.1590866875641097 0.8708520037106524 1.0789606331951869 0.3204744543463996 0.3413103865779423 1.0 1.0 1.0 0.361145714490569 +Intrinsic component of synaptic vesicle membrane 6 10 2.0015548243954093 0.0453326317937841 3.648058252427184 9.116504854368932 0.724313202500786 0.4129003553732678 2.1933086936710184 1.7154408466980504 1.018214829869002 0.3297596143558817 0.3477396452921003 1.0 0.2297987482657219 0.4846912912858679 0.1410707299584872 +Late endosome 21 67 1.9699572463703123 0.0488432706567374 15.655339805825244 65.18203883495146 0.1482522199608934 0.3683478922291265 6.675389202214119 9.543379127098556 1.7080817701484334 0.368772234437858 0.0239405171693085 0.6312378177493598 0.8646762583733004 0.3779091260107534 0.0051116973979048 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..75009aecfb19b2b03789e4dd74ed1e2e83746d36 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 908, + "title": "Average number of proteins per term", + "value": 30.70374449339207 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..80def70d65c1d929e10b53e1ac934502092bb1e6 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b87eb2ba4aaf6ec10c4294132ed31331b6bf2f72 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,280 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.6074082428539657 8.46706283035541 2.5165835714800605e-17 2.3758578829038672e-14 2.3758578829038953e-14 541 Q6IC98,O00767,Q86YN1,P04062,Q8N4V1,Q96A33,Q96A57,Q9UKR5,Q96G23,Q9Y3B3,P05067,O43852,Q5VV42,Q9BQE5,Q9BRR6,Q9NQC3,Q9P2W9,P48723,P52789,P62820,O75298,O95197,Q5J8M3,P09601,Q4ZIN3,Q6NUQ4,P80303,P67812,P51648,P84157,P18031,P43307,P36383,P30519,P20340,Q5BJH7,Q6ZXV5,O95864,O14657,O95169,Q9BUR5,Q969V3,Q8N2G8,Q9Y282,Q9Y5M8,O00560,Q16850,Q8N511,O15173,O94905,Q6NUK4,O14735,O00264,Q9NRA0,O75844,P10619,Q15738,Q9H6E4,Q96PC5,Q9NUN5,Q9NUQ2,Q9H4L5,Q643R3,Q9H0U4,Q9NWM8,O75503,O95674,Q9Y3E0,Q9UHQ4,Q07065,Q8N5M9,O14681,P50402,Q9NPA0,Q96AG4,P27105,Q15904,Q96HR9,Q9BSR8,Q15005,Q70UQ0,Q9Y2B2,Q86UE4,P27544,Q16799,O95070,Q9H2J4,Q8N2F6,O76062,P56589,Q02818,Q14257,Q9BT22,Q9Y6I9,O60725,Q6UWP7,Q12981,Q9Y2B0,Q9HCU5,Q9Y3A6,Q96RQ1,Q8N9F7,O95470,O95881,Q9NR31,P24390,P49069,Q9Y394,Q9H6V9,Q9Y679,Q6Y1H2,Q92575,Q03518,P49755,Q9H3N1,Q8N2K0,Q8TB61,Q10472,Q96AA3,P56962,Q8NHH9,Q9HD47,Q9UKU0,O00165,Q14534,Q00765,Q5SGD2,Q96S66,O95433,O43292,Q6UX53,Q15041,Q9H6H4,Q9Y673,Q9Y320,Q8NAT1,Q15125,Q8IV08,Q9Y680,Q9UBV2,Q15392,Q8N5K1,Q15800,Q9H0U3,O15260,Q9GZP9,P49257,Q53GQ0,P35613,P16615,Q99640,Q9BRK5,O15269,O43681,O95302,Q9NTJ5,Q15363,Q8NBI6,P27824,P46977,Q9Y4P3,Q8WVQ1,Q86UL3,Q92791,Q14108,Q14118,Q96GC9,A1L0T0,P52292,Q13510,Q9NWW5,P30536,Q6NTF9,Q86Y07,Q96N66,O75477,Q03519,Q96RL7,Q6NUM9,Q8TED1,O75845,Q13190,Q8TC12,Q9H1A3,Q9P035,Q9HD20,Q8NF37,P61026,P51571,Q8NBJ7,Q9UM00,Q9BUN8,Q9Y3D6,Q9UNL2,Q96S52,P30511,Q15006,O00400,Q9UEU0,Q96JJ7,Q96HY6,Q68D91,Q92604,Q99735,Q9Y5U9,Q7Z7H5,Q9NZ08,O75787,P37268,Q969X5,O76024,P57088,Q01105,Q92542,Q9Y5Z9,P16435,Q2TAA5,Q9UBU6,P55327,Q8N766,Q9H490,P00387,Q96LJ7,Q96KC8,P05023,Q15629,O15258,P51572,Q86XL3,O15155,O75396,P49458,Q8NBQ5,Q14739,Q6IAN0,O60476,Q13641,Q8NBM4,Q8NFQ8,P61019,Q9UNK0,O15118,P10321,Q96CS3,Q92643,Q5JRA6,Q6RW13,P98194,Q9UKV5 249 +Organelle subcompartment 0.63756972953484 8.330486760331603 8.051063848931173e-17 7.401165974829233e-14 3.700582987414752e-14 430 Q6IC98,O00767,Q86YN1,P04062,Q8N4V1,Q96A33,Q96A57,Q9UKR5,Q96G23,Q9Y3B3,P05067,O43852,Q5VV42,Q9BQE5,Q9BRR6,Q9NQC3,Q9P2W9,O75298,O95197,O95249,Q5J8M3,P09601,Q4ZIN3,Q6NUQ4,P18031,P67812,P51648,P43307,P36383,P30519,P20340,Q5BJH7,O00461,O95864,Q9BUR5,Q969V3,Q9Y282,Q9Y5M8,O00560,Q16850,Q8N511,O60499,O94905,O14735,Q6NUK4,O00264,O75844,Q15738,Q96PC5,Q9NUN5,Q9NUQ2,Q9H4L5,Q643R3,Q9H0U4,O95674,Q9UHQ4,Q07065,Q12893,Q8N5M9,O14681,P50402,Q9NPA0,Q96AG4,Q15904,Q96HR9,Q9BSR8,Q15005,Q70UQ0,Q9Y2B2,Q86UE4,P27544,Q16799,O95070,Q8N2F6,O76062,Q6UWP7,Q9BT22,Q9Y6I9,O60725,Q9P260,Q12981,Q9HCU5,Q9Y3A6,Q9UID3,Q96RQ1,Q8N9F7,O95470,P24390,P49069,Q9Y394,Q9Y679,Q6Y1H2,Q92575,Q12846,Q03518,P49755,Q9H3N1,Q8N2K0,Q9NX62,Q8TB61,Q10472,Q96AA3,P56962,Q8NHH9,Q9UKU0,Q14534,Q00765,Q5SGD2,Q96S66,Q9H4A6,O43292,Q9BXS4,Q6UX53,Q15041,Q9H6H4,Q9Y673,Q9Y320,Q8NAT1,Q15125,Q8IV08,Q9UBV2,Q15392,Q8N5K1,Q15800,Q9H0U3,O15260,Q9GZP9,P49257,Q53GQ0,P35613,P16615,Q99640,O15269,Q9NTJ5,Q15363,Q8NBI6,P27824,P46977,Q9Y4P3,Q8WVQ1,Q86UL3,Q14108,Q96GC9,A1L0T0,P52292,Q9BZG1,Q9NWW5,Q8TBA6,Q6NTF9,Q86Y07,Q96N66,P35670,O75477,Q03519,Q96RL7,Q9BYC5,Q6NUM9,O75845,Q13190,Q8TC12,Q9P035,Q9HD20,Q8NF37,P61026,P51571,Q9UM00,Q9BUN8,Q96L58,Q9UNL2,Q96S52,P30511,Q15006,O00400,Q9UEU0,Q96JJ7,Q96HY6,Q68D91,Q92604,Q99735,Q9Y5U9,Q7Z7H5,Q9NZ08,O75787,P37268,Q969X5,O76024,P57088,Q9Y5Z9,Q10713,O15127,P16435,Q2TAA5,Q9UBU6,Q96ED9,Q8N766,Q9H490,P00387,Q96KC8,Q15629,P51572,Q86XL3,O15155,O75396,P49458,Q14739,Q6IAN0,Q8NBM4,Q9H9E3,Q8NFQ8,O43752,P61019,Q9UNK0,P10321,Q9P2E5,Q96CS3,Q92643,Q5JRA6,Q6RW13,P98194,Q9UKV5 220 +Nuclear outer membrane endoplasmic reticulum membrane network 0.6644572679536329 7.965429494676889 1.6465089159329852e-15 1.495938095666033e-12 4.986460318890503e-13 354 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183 +Envelope 0.5603779555783487 7.585606298207563 3.3093587813496797e-14 3.00498857342041e-11 7.512471433663773e-12 539 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223 +Mitochondrial envelope 0.6275299590364193 7.458289345379594 8.76530173127026e-14 7.958984771677015e-11 1.591796954398679e-11 358 O14949,Q6IC98,Q86Y39,Q8N183,Q8N4H5,Q8TB36,Q8WY22,Q96A26,Q9BRT2,Q99595,Q9NWR8,Q9NS69,Q9Y2C4,Q9NX14,Q9UDW1,Q9Y2R0,Q9Y584,Q9Y6M9,Q69YU5,P13073,Q5XKP0,O43676,P52789,O60830,P53007,Q96BW9,Q9Y276,Q9Y512,P00846,P09601,O43169,P14406,P45880,Q9UJS0,Q13505,Q9Y5L4,P18031,P21796,Q9Y277,O95169,Q9NZ45,Q9BUR5,P20674,Q9UDX5,P57105,Q7Z7H8,Q96H78,Q9BWH2,O00264,Q9NRA0,Q9Y5J7,Q02978,Q96I36,O75964,O95167,P00403,Q8N5N7,Q9Y619,Q9NUQ2,P24539,O75431,O95674,Q9BYN8,Q96D53,Q8N8Q8,O14957,P52888,Q15070,P50336,Q9BSK2,O75746,Q9BQT8,Q9Y241,O14925,Q99623,Q96IX5,Q9BXK5,O96000,Q9Y5J9,Q9H061,Q12981,Q9UJZ1,Q6PI78,Q9NVH1,Q96KR6,P22695,Q96BR5,Q8NI60,O75947,O43674,P22830,Q6UXV4,Q96AQ8,P52815,P12235,P56556,Q9NZJ7,Q9UKU0,O00165,O60313,Q70HW3,Q9P0S9,Q9H4A6,O75027,P03886,Q9Y6C9,Q9UBX3,Q9Y320,Q15388,Q567V2,Q9H3K2,Q96DA6,Q9NPL8,Q9H2D1,Q8IUX1,P06576,Q07820,Q8N5K1,Q8NBN7,Q9Y371,P21912,Q9NR28,P56385,P50416,Q9GZY4,Q16891,O14548,O43819,P23786,Q96ER9,Q9NVI7,O95202,Q5HYI7,Q96CU9,Q9P0J0,P12236,Q7KZN9,P30536,Q86Y07,Q96RL7,Q9UG56,Q53H12,Q6UX07,Q8IWA4,Q6NUK1,O75880,Q6P4A7,Q9Y3D6,Q8WWC4,O43615,O95168,Q8TBP6,Q9HC21,Q9H300,O15235,Q6DKK2,Q9Y5Z9,Q10713,Q9BUB7,Q3ZCQ8,Q9NQZ5,O95139,P00387,Q13423,P05141,P53701,Q5T9A4,Q8IYU8,Q9NQ50,P03915,P08574,Q9NX63,P14927,P35232,O96008,O95140,Q8NBU5,Q9BRJ2,Q9Y375 179 +Organelle inner membrane 0.6628380193302925 6.872273270413623 6.318676102714061e-12 5.737358792823851e-09 8.411373189167917e-10 272 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144 +Intrinsic component of organelle membrane 0.7450627123261547 6.868577201843015 6.4845378022219635e-12 5.887961215102589e-09 8.411373189167917e-10 157 O00767,Q86YN1,Q8N4V1,Q8TB36,Q96A33,Q99595,Q9NWR8,Q9NQC3,Q9Y2R0,Q5XKP0,O60830,Q9Y512,O75298,Q13505,Q5BJH7,Q9BUR5,Q9Y282,P57105,O60499,Q9BWH2,O75844,O75431,Q8N8Q8,Q9NPA0,Q15070,O14925,O95070,Q12981,O95470,O43808,P49069,Q6Y1H2,Q5SNT2,L0R6Q1,Q8TB61,Q6UXV4,Q96AQ8,P12235,O43292,P13473,Q15041,Q15388,O94901,Q15125,Q9H3K2,Q9GZP9,O75192,P50416,Q9GZY4,Q16891,O43819,Q8NBI6,P27824,Q96ER9,Q5HYI7,Q9Y4P3,Q6NTF9,Q03519,Q9UG56,Q53H12,Q8IWA4,Q9P035,Q9UM00,O75880,Q6P4A7,Q9BUN8,Q9Y3D6,Q96S52,P30511,Q15006,Q6ZRP7,Q9Y2U8,Q9HC21,Q9Y5U9,Q969X5,O76024,P57088,Q9Y5Z9,Q9BUB7,Q8N766,Q9H490,P42892,Q15629,O15258,P51572,Q86XL3,O15155,Q9NQ11,Q14739,Q9NX63,O43752,O96008,O15118,O95140,P10321,Q92643,P98194,Q9UKV5 98 +Membrane protein complex 0.5566681656202639 6.095069540077078 1.0938988782812726e-09 9.932596896479267e-07 1.2415752279842446e-07 323 O14949,Q86Y39,Q8N4H5,Q8N4V1,Q4KMQ2,Q9Y3B3,Q99595,Q9NWR8,Q9NS69,Q9P2W9,Q9UDW1,Q9NX14,Q9Y584,Q9Y6M9,Q6IAA8,O43633,P13073,Q5XKP0,O43676,O60830,Q9Y276,Q9Y512,Q5J8M3,O95249,P00846,P14406,P45880,Q13505,P67812,P21796,P36383,Q9Y277,O95169,Q9BUR5,P20674,Q9Y5M8,O00560,Q8N511,O60499,P63218,Q9Y5J7,O60749,O75964,O95167,P00403,P24539,O75431,Q9P253,Q9NPA0,O14957,Q15904,Q9UNH7,Q15005,Q9UH99,P05556,P08195,O14925,Q99623,Q96IX5,O96000,Q12981,Q9Y3E7,Q9NVH1,Q9NR31,P22695,Q9Y679,Q12846,Q03518,P49755,Q8N2K0,O75947,O43674,Q6UXV4,P12235,P56962,Q9C0H2,Q96S66,O43292,P03886,Q15041,Q15388,O94901,Q96DA6,Q9UBV2,P06576,Q9UBQ0,Q9H0U3,P21912,Q9GZP9,Q9NR28,P56385,Q53GQ0,Q16891,O14548,O15269,Q96ER9,Q5HYI7,Q96CU9,Q9P0J0,P46977,P12236,Q14118,Q6NTF9,Q03519,Q53H12,Q13190,Q8IWA4,P51571,Q9BUN8,Q96S52,P30511,Q15006,Q9UEU0,O15400,O95168,O75787,Q92542,O95721,Q9UBU6,Q3ZCQ8,O95139,Q8N766,Q9H490,P05023,P05141,O15155,O75396,P49458,Q8IYU8,P03915,P08574,Q93050,Q9NX63,P14927,P35232,O43752,O96008,Q9UNK0,P10321,Q96CS3,Q92643,Q9UKV5,Q9Y375 143 +Inner mitochondrial membrane protein complex 0.7213708472341147 5.519130364115182 3.406813954616444e-08 3.093339278849364e-05 3.437096745425035e-06 91 O14949,P21912,Q86Y39,O95168,O14925,Q99623,P56385,O96000,Q99595,Q9NWR8,Q16891,Q9NX14,Q9UDW1,O14548,Q9Y584,Q9Y6M9,P13073,Q5XKP0,O43676,Q9Y276,O60830,P22695,Q5HYI7,Q96CU9,Q9P0J0,P00846,Q3ZCQ8,O95139,P14406,P12236,Q13505,Q6UXV4,Q9BUR5,P20674,Q53H12,Q8IYU8,Q9Y5J7,P03886,P03915,P08574,O75964,O95167,P00403,Q9NX63,P14927,P35232,P24539,O75431,Q96DA6,P06576,O14957,Q9Y375 52 +Mitochondrion 0.4317371741885046 5.453996593765704 4.92501455761782e-08 4.471813339975356e-05 4.47191321840778e-06 678 O14949,Q6IC98,Q86Y39,Q8N183,Q8N4H5,P28288,Q8TB36,Q8WY22,Q96A26,Q9BRT2,Q96ND0,Q99595,Q9NWR8,Q9NS69,Q9Y2W6,Q9Y2C4,Q9NX14,Q9UDW1,Q9Y2R0,Q9Y584,Q9Y6M9,P48723,Q9NUJ1,Q69YU5,P13073,Q5XKP0,O43676,P52789,O60830,P53007,Q96BW9,Q9Y276,Q9Y512,P00374,P00846,P09601,O43169,P14406,P45880,Q9UJS0,Q13505,Q9Y5L4,P18031,P21796,P11182,Q9HCC0,Q9Y277,O95169,Q9NZ45,Q3SXM5,Q9BUR5,P20674,Q9UDX5,P57105,Q6P087,Q7Z7H8,Q96H78,Q9BWH2,O00264,Q9HA77,Q9Y5J7,Q9NRA0,Q8NBX0,Q96I36,Q02978,O75964,O95167,P00403,Q8N5N7,Q9Y619,Q9NUQ2,P24539,O75431,O95674,Q9H6K4,Q96D53,Q8N8Q8,Q96AG4,Q9BWD1,O14957,Q15070,Q15165,Q9BSK2,Q9BQT8,Q9Y241,O14925,Q99623,Q9BXK5,Q9NRP2,Q8N2F6,O96000,Q9Y5J9,Q9H061,Q12981,Q6PI78,P22695,Q9NPH0,P22830,Q6UXV4,Q96AQ8,P12235,P56962,Q9NZJ7,Q9UKU0,O00165,O60313,Q70HW3,Q9P0S9,Q9H4A6,O75027,O43292,P03886,Q9Y6C9,Q9UBX3,Q9Y320,Q15388,Q567V2,Q9H3K2,Q9H7Z7,Q96DA6,Q9BW91,Q9NPL8,Q9H2D1,Q8IUX1,P06576,Q07820,Q8N5K1,Q8NBN7,Q9Y371,P21912,Q9NR28,Q16740,Q8NCN5,P56385,P50416,Q9GZY4,P35613,Q16891,O14548,O43819,P23786,Q96ER9,Q9NVI7,O95202,Q5HYI7,Q96CU9,Q9P0J0,P12236,Q7KZN9,P30536,Q86Y07,P35670,Q96RL7,Q9UG56,Q53H12,Q6UX07,Q8IWA4,Q9H1A3,Q6NUK1,O75880,Q6P4A7,Q9Y3D6,Q8WWC4,Q9BY49,O43615,Q9HC38,O95168,Q8TBP6,Q9HC21,Q9H300,O15235,Q92542,Q6DKK2,Q9Y5Z9,Q10713,P16435,Q9BUB7,Q3ZCQ8,Q9NQZ5,O95139,O14874,O75131,P00387,Q8TAE8,Q13423,P51572,Q9NR77,P05141,P53701,Q5T9A4,Q8IYU8,Q9NQ50,P03915,P08574,Q9NX63,P14927,P35232,O96008,O95140,Q7L592,O00116,Q8NBU5,Q9BRJ2,Q9Y375 204 +Intrinsic component of endoplasmic reticulum membrane 0.7282614118241618 5.285090596665512 1.2564256174027797e-07 0.0001140769459582 9.85709113265589e-06 65 O00767,Q86YN1,Q9GZP9,Q8N4V1,Q16799,Q96A33,O76062,Q969X5,Q9NQC3,O76024,P57088,Q12981,Q9HCU5,O95470,Q8NBI6,P27824,O75298,Q5J8M3,P49069,Q9Y679,Q6Y1H2,Q9Y4P3,Q8N766,Q9H490,Q8TB61,Q15629,Q6NTF9,Q9Y282,Q03519,P51572,Q86XL3,O43292,Q9P035,O75844,Q15041,Q9UM00,Q9BUN8,Q15125,Q96S52,P10321,Q92643,Q15006,P30511,Q9NPA0,Q9UKV5 45 +Intrinsic component of mitochondrial membrane 0.7604093375384052 5.278465864997116 1.3026992686229369e-07 0.0001182781058895 9.85709113265589e-06 55 Q8TB36,Q9HC21,O14925,P50416,Q99595,Q9NWR8,Q9GZY4,Q16891,Q9Y2R0,O43819,Q5XKP0,O60830,Q96ER9,Q9BUB7,Q5HYI7,Q13505,Q6UXV4,Q96AQ8,P12235,Q9BUR5,P57105,Q9UG56,Q53H12,Q8IWA4,Q9BWH2,O75880,Q9NX63,Q6P4A7,Q15388,Q9Y3D6,O96008,O75431,Q9H3K2,O95140,Q8N8Q8,Q15070 36 +Golgi membrane 0.5999122832306915 5.243317108197556 1.5771513568828698e-07 0.0001431951011013 1.1015795631220963e-05 153 O15260,Q8N6H7,Q8N4V1,P49257,P51790,Q9Y3B3,O95070,Q7LGA3,Q9Y5U9,Q969X5,P35613,Q99640,Q9P2W9,Q9Y5Z9,Q10713,Q9NTJ5,Q15363,P62820,O95721,P24390,O95197,O95249,L0R6Q1,P49755,Q14108,Q8TB61,Q10472,P20340,P52292,Q5BJH7,Q8TBA6,O00461,Q6NTF9,Q9BUR5,Q8IZA0,P35670,Q9Y282,Q6NXT4,O15258,P51572,Q9BYC5,O60499,Q8NCH0,O15155,O75396,Q13190,Q96S66,Q9H4A6,Q9BXS4,Q8NF37,P61026,O60476,Q9UM00,Q9H9E3,Q9Y2C2,P98194,Q9NXS2,O43752,Q9H0U4,Q8IV08,Q96L58,Q9H7Z7,P61019,Q9Y3E0,P10321,Q92896,Q9P2E5,P30511,Q6ZRP7,Q15392,O00400,Q6RW13,Q9Y371 73 +Outer membrane 0.6484836623191611 4.96061687304423 7.026966702515868e-07 0.000637845290916 4.534939939699135e-05 99 Q8N4H5,Q8TB36,Q8WY22,Q99623,Q8IWB1,P50416,Q9NS69,Q16891,P52789,Q5XKP0,Q5HYI7,Q9NQZ5,P09601,O43169,P45880,Q13505,P00387,P21796,Q6UXV4,Q9Y277,P30536,Q9NZ45,Q9BUR5,Q9NZJ7,Q9UKU0,O00165,P57105,Q96RL7,O60313,Q6NUM9,Q53H12,Q9BWH2,O00264,Q8IWA4,Q9Y6C9,Q9NX63,Q15388,Q9Y3D6,O75431,O96008,O95140,P50402,Q07820,Q8N5K1,Q8NBU5,Q9Y371 46 +Mitochondrial protein containing complex 0.5717720068831134 4.948164954663133 7.491640869537029e-07 0.000680009934137 4.534939939699135e-05 177 O14949,Q86Y39,Q8N4H5,Q99595,Q9NWR8,Q9NS69,Q9NX14,Q9UDW1,Q9Y584,Q9Y6M9,P13073,Q5XKP0,O43676,Q9Y276,Q9Y512,O60830,P00846,Q9Y5L4,P14406,Q13505,P11182,P21796,Q9HCC0,O95169,Q9BUR5,P20674,Q7Z7H8,Q9Y5J7,O75964,O95167,Q8N5N7,P00403,P24539,O75431,Q9BYN8,O14957,O14925,Q96IX5,Q99623,O96000,Q9Y5J9,Q9NVH1,P12694,P22695,O75947,P09622,O43674,Q6UXV4,P52815,P12235,P03886,Q15388,Q567V2,Q96DA6,P06576,P21912,P56385,Q16891,O14548,Q5HYI7,Q96CU9,Q9P0J0,P12236,Q53H12,Q8IWA4,O95168,O15235,Q3ZCQ8,O95139,O14874,P05141,Q8IYU8,Q9NQ50,P03915,P08574,Q9NX63,P14927,P35232,O96008,Q9BRJ2,Q9Y375 81 +Golgi apparatus 0.4721410438317973 4.783251868946758 1.724817759261038e-06 0.0015649101252496 9.788340783812064e-05 339 P04062,Q8N4V1,Q8N6H7,Q96M27,Q96A57,Q9Y3B3,O43852,P05067,Q9P2W9,P62820,O95197,O95249,Q92544,Q6NUQ4,P80303,P20340,Q5BJH7,O00461,Q9BUR5,Q9Y282,O60499,Q8NCH0,O14735,Q9NX40,Q92520,Q9Y2C2,Q9NXS2,Q9H0U4,O75503,Q9Y3E0,P50897,Q8N1S5,Q92896,Q12893,O14681,Q68CQ7,Q9BSR8,Q96A49,Q16799,O95070,Q7LGA3,O96013,O95235,O14773,Q02818,Q9P260,Q9Y3A6,Q96RQ1,Q5VW38,Q9NR31,P24390,L0R6Q1,P49755,Q9NX62,Q8TB61,Q10472,Q96S66,Q9H4A6,Q9BXS4,Q8IV08,Q9H7Z7,Q15392,Q8NEW0,Q9Y371,O15260,P49257,Q7Z3D4,P35613,Q99640,Q9BRK5,Q9NTJ5,Q15363,Q8WVQ1,Q14108,Q14118,P52292,Q9BZG1,Q8TBA6,Q6NTF9,P35670,Q96RL7,Q9BYC5,Q9NQX7,Q13190,Q8NF37,P61026,Q9UM00,Q96L58,P30511,Q6ZRP7,O00400,Q9UEU0,Q9Y5U9,P51790,Q7Z7H5,Q969X5,Q92542,Q9Y5Z9,Q10713,O15127,O95721,Q96ED9,P05023,Q99805,Q8IZA0,Q6NXT4,O15258,P51572,O15155,O75396,O60476,Q93050,Q9H9E3,O43752,P61019,Q9UNK0,O15118,P10321,Q9P2E5,Q6RW13,P98194,Q9UKV5 122 +Respirasome 0.6911317467791941 4.655721013138551 3.228488655970807e-06 0.0029271798619697 0.0001724392764483 54 O14949,P21912,Q86Y39,O95168,Q9Y241,O96000,Q9NX14,O14548,Q9UDW1,Q6DKK2,Q9Y6M9,P13073,O43676,Q9Y276,P22695,Q96CU9,Q9P0J0,O95139,P14406,Q7KZN9,Q13423,P20674,P03886,P03915,P08574,O95167,P00403,P14927,O14957,Q9Y375 30 +Intrinsic component of mitochondrial inner membrane 0.7723297576407445 4.357438342455886 1.3159355263914208e-05 0.0118776700884818 0.0006638163655352 36 Q9HC21,O14925,Q99595,Q9GZY4,Q9NWR8,Q16891,Q9Y2R0,O43819,Q5XKP0,O60830,Q96ER9,Q5HYI7,Q13505,Q6UXV4,Q96AQ8,Q9BUR5,Q9UG56,Q53H12,O75880,Q9NX63,Q6P4A7,O75431,Q9H3K2,Q8N8Q8,Q15070 25 +Endoplasmic reticulum golgi intermediate compartment 0.610310596875366 4.22800061565381 2.357771470640202e-05 0.02118127530474 0.0010704282476706 59 O15260,P49257,O95070,Q7Z7H5,Q969X5,Q02818,Q9Y3A6,Q96RQ1,Q15363,P24390,P49755,P80303,Q10472,Q96GC9,Q5BJH7,P56962,Q9Y282,Q03519,O15258,P51572,Q8N511,O15155,O75396,Q13190,P61019 25 +Endoplasmic reticulum golgi intermediate compartment membrane 0.753742296979034 4.091600138400022 4.284068805526786e-05 0.0381532821972805 0.0018523497501992 32 O15260,P49257,Q9Y3B3,O95070,Q969X5,Q9Y3A6,Q96RQ1,Q15363,P24390,Q03518,P49755,Q10472,Q96GC9,Q5BJH7,P56962,Q9Y282,Q03519,P51572,Q8N511,O15155,O75396,Q13190,Q9H0U4,P61019,Q15904 25 +Endoplasmic reticulum protein containing complex 0.5567480903757122 3.7562881201993794 0.0001724521442432 0.1449540342404875 0.0057995017397349 71 Q9GZP9,Q8N4V1,Q53GQ0,O15269,O43681,Q9UBU6,P49069,P46977,Q8N766,Q9H490,P67812,Q6NTF9,Q03519,Q9Y5M8,P49458,O43292,P51571,Q15041,Q9BUN8,Q96S52,Q9UBV2,Q96CS3,Q92643,Q15006,Q9NPA0,Q9UKV5,Q15005,Q9H0U3 28 +Microbody membrane 0.7151501521098159 3.714556189803482 0.0002035606362911 0.1687725977735789 0.0066011806340121 28 P40855,P28288,Q9UKU0,Q8TB36,O43808,Q15067,Q5T8D3,Q9NR77,Q9Y3D6,O75192,Q9BY49,O75381,Q8NBU5,O00116,P51648,Q6IAN0 16 +Triglyceride rich plasma lipoprotein particle 0.9699094361671056 3.692372056306471 0.0002221721186133 0.1827046113611481 0.0068618622084042 2 Q9BUR5 1 +Transporter complex 0.551249311147324 3.687166052266139 0.0002267653919585 0.1861069625702949 0.0068618622084042 67 O14949,Q86Y39,O95168,Q4KMQ2,O96000,Q9Y5J9,Q9NWR8,Q9NX14,Q9UDW1,Q9Y6M9,O43676,Q9Y276,Q96ER9,P22695,Q96CU9,Q9P0J0,O95139,Q9Y5L4,P05023,Q9C0H2,Q96S66,Q8IYU8,Q9Y5J7,P03886,P03915,P08574,O95167,P14927,O75381,O14957,Q9Y375 31 +Smooth endoplasmic reticulum membrane 0.9442009932807502 3.5758278071952563 0.0003491214015611 0.271711182140506 0.0087245296665155 2 O00264 1 +Secretory granule membrane 0.5326694411741405 3.5251647148040317 0.0004232195486879 0.3191169302177878 0.0096070837552166 74 O15260,Q4KMQ2,O75787,P35613,Q9NP72,Q92542,Q6IAA8,O95721,Q15363,P07602,P49755,P11279,O75131,P30519,P20340,O60645,Q8NHP6,Q9NZJ7,Q08722,Q5T9A4,Q9NQX7,O00264,P13473,Q8NF37,P61026,Q969Q5,Q93050,P10321,Q07065,O14975,P61225,P27105,Q14254,Q96JJ7,Q9Y5K8,Q9H0U3 36 +Golgi cisterna 0.6826376283230753 3.4912232210462233 0.0004808143561398 0.3538246845421198 0.0106482789115859 28 Q15363,P51572,O95249,Q96L58,Q9BYC5,Q9BXS4,Q8WVQ1,O15155,Q9P2E5,Q9H4A6,Q10472,Q9BZG1,O00461,Q8TBA6,Q10713 15 +Intrinsic component of plasma membrane 0.5203062296158126 3.4691013367559065 0.0005222024435946 0.37766930628837 0.0110269725298599 86 Q99808,Q96QD8,O43657,P05556,Q9NR28,P04439,Q15758,P51790,P05067,O76062,P11166,P35613,P16615,Q9UIW2,Q99797,Q92542,Q9Y639,O60637,P27824,Q9UJS0,Q8N2K0,P20020,Q15043,P11279,P05023,P12235,O95864,P30825,Q8NHP6,Q99805,P35670,Q08722,O00560,P60033,P51572,P05141,O00264,Q02978,P55011,O96005,P78310,P10586,Q13641,P54709,P35232,O43464,Q9UNK0,Q8WTV0,O15118,A0FGR8,P10321,P27105,O00400,Q9H0U3 54 +Autolysosome 0.9103125912941888 3.419536738677791 0.000627278614582 0.434331858969305 0.0116267507906692 2 P13473 1 +Secondary lysosome 0.9103125912941888 3.419536738677791 0.000627278614582 0.434331858969305 0.0116267507906692 2 P13473 1 +Endoplasmic reticulum tubular network membrane 0.9351832024560404 3.389058914025028 0.0007013294063544 0.4711394599129103 0.0116267507906692 3 Q9NQC3 1 +Copii coated er to golgi transport vesicle 0.6192570643820368 3.38296858951881 0.000717068330702 0.4786489151113538 0.0116267507906692 40 Q9Y5U9,P49257,Q9Y3B3,Q7Z7H5,O95070,Q969X5,Q9Y3A6,Q96RQ1,Q15363,Q9NR31,P49755,Q5BJH7,P56962,Q9Y282,O75396,Q13190,P10321,P30511,Q9UEU0 19 +Cytochrome complex 0.7951472032912 3.3755096895924326 0.000736790975123 0.4879089232091161 0.0117369509721352 19 O14949,P13073,P14927,P20674,P22695,P14406,Q7KZN9,O14957,O14548,P08574,Q9UDW1,P00403 12 +Azurophil granule membrane 0.724241513012222 3.3593062871792743 0.0007813841134056 0.5082447345563961 0.0118377160095756 23 O15260,O95721,Q9NZJ7,Q8NF37,Q9NQX7,Q07065,P07602,P11279,O75131,P13473,Q92542,Q6IAA8,Q9H0U3 13 +Transport vesicle 0.4917001537857092 3.3123671079372787 0.0009251006529027 0.5684535691640776 0.0133331967116776 102 O15260,O15400,P49257,Q9UKR5,Q9Y3B3,Q96A57,P51790,P05067,O43760,O76024,Q92542,Q15363,P62820,Q9NR31,P24390,O95249,Q15907,P49755,P11279,Q9BT78,Q8TBA6,O00461,P56962,O60499,O15155,O75396,Q13190,Q9NQ11,P61026,O43752,P50897,P10321,P30511,Q9UEU0 34 +Gamma secretase complex 0.8805141688577325 3.2795025052289892 0.0010399028689571 0.6112127889488213 0.0140227413887245 2 P49755 1 +Inhibitory synapse 0.879929886064855 3.276731656352271 0.0010501612493758 0.6148211295411694 0.0140227413887245 2 P51790 1 +Zymogen granule membrane 0.9079777396322184 3.2645766527734783 0.0010962779532259 0.6306336870506631 0.0141626776703624 3 P49755 1 +Outer mitochondrial membrane protein complex 0.8038352032447941 3.24507224206806 0.0011742083070995 0.6558947099316261 0.0142157485712855 17 Q5XKP0,Q9NX63,Q9BUR5,Q8N4H5,Q15388,O96008,O75431,Q5HYI7,Q13505,Q8IWA4,Q9NS69,Q16891,Q6UXV4 13 +Golgi trans cisterna 0.8653228162430673 3.2071406740471153 0.0013406142217051 0.7042067040811626 0.0153532456051807 2 Q9BXS4 1 +Oxidoreductase complex 0.5013291033661662 3.1867677949509736 0.0014387223036769 0.7294505799776592 0.0153532456051807 71 O14949,P21912,Q86Y39,O95168,O96000,Q9NX14,Q9UDW1,Q9Y6M9,O43676,P12694,Q9Y276,P22695,Q96CU9,Q9P0J0,O95139,O14874,O43169,P00387,P11182,P09622,O43674,O95169,P03886,P03915,P08574,O95167,P14927,O14957,Q9Y375 29 +Signal peptidase complex 0.8908009147742659 3.184957343604347 0.0014477534670895 0.73166327405997 0.0153532456051807 3 P67812 1 +Snare complex 0.7279870260585289 3.1717149673239415 0.0015154166416946 0.7476761684363026 0.0154606551759407 21 P56962,O95721,O15400,O43752,O95249,O60499,O15155,O75396,Q13190,Q9P2W9,Q12981,Q9UEU0 12 +Golgi stack 0.605757378206361 3.1440966293916977 0.001666004172389 0.7799704225210543 0.016783505246803 36 Q15363,P51572,O95249,Q96L58,Q9BYC5,Q9BXS4,Q8WVQ1,O15155,Q9P2E5,Q9H4A6,Q10472,Q9BZG1,O00461,Q8TBA6,Q10713 15 +Nuclear inner membrane 0.6756537628359406 3.044642114447419 0.0023295733955146 0.8796944225696284 0.0212982087964548 23 Q9H1E5,Q9BTV4,O94901,Q13185,Q8IXM6,Q14728,Q5SNT2,O76062,Q9Y2U8,P50402,Q14739,O75844,Q8N6S5,Q9UH99 14 +Zymogen granule 0.8895702939346534 3.0402071343724506 0.0023641549356718 0.8834219412126539 0.0212982087964548 4 P49755 1 +Coated vesicle 0.4698328542596584 3.038391213206716 0.002378449626428 0.8849288479781802 0.0212982087964548 101 P49257,Q9Y5U9,Q9Y3B3,O95070,Q7Z7H5,Q969X5,Q9Y3A6,Q96RQ1,Q15363,Q5VW38,Q9NR31,P24390,P49755,Q14108,P42892,Q5BJH7,P56962,Q9Y282,O00165,P51572,Q8N511,O75396,Q13190,Q9NUN5,O43752,P10321,P30511,Q96HR9,Q9UEU0 29 +Tim22 mitochondrial import inner membrane insertion complex 0.8874465739734171 3.0304112146783364 0.0024422097879164 0.8914168170599228 0.0212982087964548 4 Q9Y584,Q9Y5J7 2 +Autophagosome membrane 0.7352110647885035 3.0261071171849063 0.0024772452558987 0.8948249720680191 0.0212982087964548 19 P56962,O95721,P13473,O75787,Q9NQ11,P11279,Q9Y6I9,Q96GC9,O15321,O43633,Q9Y371 11 +Exocytic vesicle 0.5619667997011877 3.0221560879536056 0.0025098109484809 0.8978969773919385 0.0212982087964548 43 O15400,P51790,Q96A57,P05067,O43760,O76024,Q14141,Q92542,P61020,Q15907,Q12846,Q9BVK6,P11279,Q9BT78,P20340,O60499,P61026,O43752,P20339,P50897,Q9UEU0 21 +Proton transporting two sector atpase complex 0.6441393139688131 2.9406502800159204 0.0032752408359815 0.94914615217053 0.02541810836813 24 Q93050,P24539,Q96IX5,Q8N511,P00846,Q9Y487,P56385,O75787,P36543,O75947,P06576,Q15904,P36542,O75964 14 +Mitochondrial crista 0.836060783167737 2.9257067886442623 0.0034367468466505 0.9561043807131984 0.0261388704128952 3 O60313,Q9BUB7 2 +Intrinsic component of golgi membrane 0.8091248390328101 2.9215213894447456 0.0034832635682382 0.9579259696037304 0.0261388704128952 14 Q9Y282,O15258,Q9Y5U9,O95070,O15155,L0R6Q1,Q969X5,Q6ZRP7,Q8TB61,Q5BJH7,Q9Y5Z9 11 +Respiratory chain complex iv 0.8425642132632988 2.840797440038504 0.0045000885806552 0.9833492824724372 0.0309551547820827 11 P13073,P20674,P22695,P14406,P00403 5 +Lipid droplet 0.5847905758092393 2.8243741893356944 0.0047373042478691 0.9865891773985443 0.0322166257056926 30 P51572,Q8NF37,Q96RL7,Q9H6V9,Q07065,Q96CS3,Q8NBQ5,O43760,P00387,Q8NBX0,Q01105,Q6UX53,Q15738 13 +Endoplasmic reticulum lumen 0.4668877813902111 2.8110837001463 0.0049374939600372 0.9888280497011146 0.0322166257056926 67 Q9BS26,Q32P28,Q9NZ08,O43852,P05067,Q02818,Q14257,O76024,O43681,O95881,P27824,P53634,P07237,Q14118,Q9NWW5,O14657,Q8TED1,O00584,P30533,Q8NBJ7,P30040,Q9BTV4,O75718,Q9NWM8,Q9Y680,O14975,Q07065,O15460,Q5JRA6,P13674 30 +Nadh dehydrogenase complex 0.5800099042352664 2.810409838793295 0.0049478449737576 0.9889330765159648 0.0322166257056926 31 O95169,Q86Y39,O95168,O43676,Q96CU9,Q9P0J0,O95139,P03915,O96000,O95167,P03886,Q9NX14,O43674,Q9Y6M9,Q9Y375,P56556 16 +Micos complex 0.8602339181286678 2.8078847977578523 0.0049868062697708 0.9893196315610664 0.0322166257056926 5 Q5XKP0,Q9BUR5,Q6UXV4,Q16891 4 +Endoplasmic reticulum plasma membrane contact site 0.781478235465976 2.7952733114674047 0.0051855854820415 0.9910916138485364 0.0322500795732444 2 Q9NTJ5 1 +Acrosomal membrane 0.7776803973123102 2.7760950911992324 0.0055016115046475 0.9933241277199764 0.0333838968979844 2 P35613 1 +Vacuolar membrane 0.410491211098587 2.7753070710886973 0.0055149609412969 0.9934050022263484 0.0333838968979844 134 O15260,P04062,O15400,Q8NCG7,P08195,P51790,P11117,O75787,Q9Y6I9,Q92542,Q6IAA8,O43633,O95721,P07602,Q15043,P11279,Q14108,O75131,Q96GC9,O15321,P42892,P56962,Q9NZJ7,Q96RL7,Q8N511,Q9NQX7,Q9NQ11,Q9NRA0,Q9BXS4,P13473,Q8NF37,P10619,Q93050,Q9NUN5,O75503,Q8IV08,Q9P253,P61019,Q9UNK0,O15118,Q07065,P30511,P27105,Q9UEU0,Q9H0U3,Q9Y371 46 +Presynaptic cytoskeleton 0.7671633070406156 2.7227407974938607 0.006474283224664 0.9972544166856208 0.0379267688257738 2 P07196 1 +Mitochondrial intermembrane space protein transporter complex 0.8196878169997122 2.7113090730032576 0.0067018124673312 0.997769943535395 0.0385974606211438 4 Q9Y5J9,Q9Y5J7 2 +Tim23 mitochondrial import inner membrane translocase complex 0.8514526801510036 2.710593141615833 0.0067162982138113 0.99779927905893 0.0385974606211438 7 O60830,O14925,Q96DA6,P12236,Q99595 5 +Dendritic spine membrane 0.7616126205083349 2.6944351719269286 0.0070508041146759 0.998379153725667 0.040264969409596 2 O75787 1 +Autophagosome 0.5667149950995829 2.6847894505165497 0.0072575510148769 0.9986583911683948 0.0411866020094264 30 P56962,O95721,P13473,Q969Q5,Q96A57,Q9P253,O75787,Q9NQ11,P11279,Q9Y6I9,Q96GC9,O15321,Q9Y3E7,O43633,Q9Y371 15 +Intrinsic component of mitochondrial outer membrane 0.7430673244321914 2.67206027630284 0.0075387105572717 0.9989626453351248 0.0414857526424408 15 Q15388,Q9Y3D6,O96008,P57105,O95140,P50416,Q8IWA4,Q9BWH2 8 +Haus complex 0.808243203741596 2.6561192381109087 0.0079045659560612 0.9992577787415778 0.0422196816947272 4 Q96CS2,Q9H6D7,O94927 3 +Golgi cisterna membrane 0.6586159184285818 2.642528603144454 0.0082289514417772 0.9994484623828894 0.0436952509306067 20 Q15363,P51572,Q10713,Q96L58,Q9BYC5,Q8WVQ1,Q9P2E5,Q9H4A6,P98194,Q10472,O00461 11 +Endoplasmic reticulum tubular network 0.8019428015884221 2.638740169423874 0.008321473324317 0.9994932594305744 0.0439296382469763 11 Q9H6H4,Q8NHH9,Q00765,Q6NUK4,P50402,Q9NQC3 6 +Cell body membrane 0.7499269646508891 2.6345104742078886 0.008425870409636 0.9995394570326894 0.0442236435372805 2 P20020 1 +Gpi anchor transamidase complex 0.8214888224779493 2.625327614759471 0.0086565630507347 0.999627166214249 0.0448081995956727 5 Q9H490,Q96S52,O43292 3 +Transport vesicle membrane 0.5000213239333785 2.6222693045116716 0.0087346380269097 0.99965289797021 0.0448081995956727 47 P56962,Q15363,Q9NR31,O43752,P49257,Q9Y3B3,O60499,P10321,Q15907,O75396,P49755,Q13190,P30511,O43760,O76024,Q9UEU0 16 +Mitochondria associated endoplasmic reticulum membrane 0.8067079305298909 2.6180049180223444 0.0088445530392737 0.9996861450507812 0.04486510703721 10 P56962,Q9Y320,P27824,Q96N66,Q15388,P51572,Q96S66 7 +Golgi medial cisterna 0.8149599029502167 2.594149802599137 0.0094825160584666 0.9998250844586668 0.0468510215167764 5 O95249,Q9BXS4 2 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.8137474973783567 2.5883467823885735 0.0096437839001861 0.9998491240205288 0.0468510215167764 5 O75964,P24539 2 +Phagocytic vesicle membrane 0.5613184955803541 2.583336299201186 0.0097849890777503 0.9998674465277156 0.0468510215167764 27 Q93050,Q03519,P10321,Q12846,Q15907,Q03518,Q9Y487,O75396,P30511,P11279,P13473,P61026,Q9BZG1 13 +Proton transporting atp synthase complex coupling factor f o 0.8243207086887442 2.5821851686937833 0.0098176893120967 0.999871362237022 0.0468510215167764 7 P00846,O75964,P24539 3 +Vesicle membrane 0.3836991413007015 2.581305366354965 0.0098427475287572 0.99987428446842 0.0468510215167764 270 Q4KMQ2,Q8N4V1,Q9Y3B3,Q6IAA8,O43633,P62820,Q15043,P20340,P30519,Q92783,O00461,Q15057,Q8N511,O60499,O00264,O43924,O60749,Q969Q5,Q9P253,Q07065,P27105,Q15904,Q96HR9,Q9UNH7,Q9UH99,P05556,Q9Y3E7,Q9NR31,P24390,Q5VWJ9,Q15907,P07602,Q03518,P49755,Q12846,O60645,P56962,Q8NHP6,Q9NZJ7,Q08722,Q9BZF3,Q9Y487,Q9BXS4,P13473,O60831,Q8IV08,Q9UBQ0,Q9H0U3,O15260,P49257,P35613,O43760,Q15363,P11279,Q14108,Q9BZG1,Q03519,Q96RL7,Q9NQX7,Q13190,Q8NF37,P61026,P55899,P30511,Q9UEU0,Q96JJ7,O15400,P51790,Q14728,O75787,O76024,Q92542,O15127,O95721,O75131,P42892,Q99805,Q5T9A4,O75396,Q9NQ11,Q93050,O43752,Q9UNK0,O15118,P10321,P61225,Q6RW13 87 +Nuclear pore central transport channel 0.7901448126795358 2.5680548013607862 0.0102270986569661 0.9999116334729868 0.0481150548213743 4 Q8NFH5 1 +Mib complex 0.7873367820922225 2.5648450808923937 0.010322188059292 0.9999190156656776 0.0483120966898825 11 Q5XKP0,Q9NX63,Q9BUR5,Q9Y512,O75431,Q5HYI7,Q13505,Q16891,Q6UXV4 9 +Organelle membrane contact site 0.7041028121902215 2.5596424494829333 0.0104779904042535 0.999929803359386 0.0487898219849345 16 P56962,Q5XKP0,Q9NTJ5,Q9Y320,P27824,Q96N66,Q15388,P51572,Q96S66 9 +Hrd1p ubiquitin ligase erad l complex 0.8035485166777301 2.539364045767723 0.0111054198432529 0.9999605363760572 0.0511104417456621 5 Q6NTF9,Q9GZP9,Q9UBV2 3 +Respiratory chain complex iii 0.7977091119815891 2.531286136871495 0.011364509732338 0.9999688923858928 0.0518541449093615 9 O14949,P14927,P22695,O14957,Q9UDW1,P08574 6 +Sperm annulus 0.7414528406760614 2.4565102153495983 0.0140293813405791 0.9999973178203608 0.0612436454675283 3 Q14141 1 +Intrinsic component of vacuolar membrane 0.7667283403881879 2.452658406128904 0.0141804928336113 0.9999976662941202 0.0616071171910004 4 P13473,Q9NQ11 2 +Er ubiquitin ligase complex 0.8019888856390927 2.4393763840443703 0.0147126353825655 0.999998570693482 0.0633131418358743 6 Q6NTF9,Q9BUN8,Q9GZP9,Q9UBU6,Q9UBV2 5 +Proton transporting atp synthase complex 0.7466658814154249 2.399382530785971 0.0164227482155736 0.9999997048138152 0.0668693066356093 12 O75964,P00846,P06576,P24539 4 +Uniplex complex 0.7543071391237011 2.390771024768217 0.0168130348361192 0.9999997941315306 0.0681528376392692 4 Q9NWR8,Q8IYU8 2 +Golgi apparatus subcompartment 0.4172574797428933 2.3800809366889233 0.0173088358521076 0.9999998697785836 0.0692847683207151 101 P04062,Q96A57,Q10713,O15127,Q15363,O95249,Q96ED9,Q8WVQ1,Q9NX62,Q10472,Q9BZG1,Q8TBA6,O00461,P35670,P51572,Q9BYC5,O60499,O15155,Q9H4A6,Q9BXS4,P61026,Q9H9E3,O43752,Q96L58,Q9UNK0,Q9P2E5,P98194,Q9BSR8 28 +Emc complex 0.7787810601629525 2.361980230671638 0.0181776115252318 0.999999941668731 0.0723915406355726 7 Q8N766,Q15006,Q9NPA0,Q8N4V1 4 +Specific granule membrane 0.6399662444209979 2.3599278156531023 0.0182784913482256 0.9999999468648456 0.0724754154768074 18 Q8NHP6,Q4KMQ2,Q08722,Q07065,O14975,O00264,P61225,P27105,P30519,Q6IAA8 10 +Proton transporting two sector atpase complex proton transporting domain 0.7470386045458103 2.357461467925855 0.0184003648065715 0.9999999525294142 0.0726414401929 11 Q93050,P24539,P00846,P56385,O75787,O75947,O75964 7 +Mitochondrial permeability transition pore complex 0.7448713069898759 2.343441672415414 0.0191067495033603 0.9999999753086108 0.0740257586340663 4 P12235,P21796 2 +Intrinsic component of peroxisomal membrane 0.7731643115629616 2.3344066582382665 0.0195744384820855 0.9999999839867296 0.0752759307278104 7 O75192,Q9Y3D6,O43808,P56589 4 +Er to golgi transport vesicle membrane 0.5435543122034545 2.320674839225944 0.0203043996657512 0.9999999918572484 0.0767702596297952 25 P56962,Q15363,Q9NR31,P49257,P10321,O75396,P49755,Q13190,P30511,Q9UEU0 10 +Platelet dense granule 0.7400431282280855 2.3191177723788887 0.0203886513667839 0.9999999924689176 0.0767702596297952 4 Q92520 1 +Recycling endosome 0.4814118557903749 2.306710501764113 0.0210709644118125 0.9999999959996426 0.0775009336251471 43 O15127,O15400,P05556,P51790,Q96A57,Q9UNK0,P10321,Q15907,P05067,P30511,O14773,P61225,Q9P260,P61026,Q9UEU0,Q9UID3 16 +Prefoldin complex 0.7735936105625023 2.302337450046443 0.0213161494252531 0.9999999968134614 0.0779182441386887 6 Q9NUG6,Q99471 2 +Bloc complex 0.6856558574350005 2.2966241175101234 0.0216402216171203 0.9999999976410446 0.0780392244699145 2 Q86YV9 1 +Sodium potassium exchanging atpase complex 0.7101110461718252 2.2948031254077037 0.0217444094613308 0.999999997858474 0.0780392244699145 3 P54709,P05023 2 +Atpase dependent transmembrane transport complex 0.7101110461718252 2.2948031254077037 0.0217444094613308 0.999999997858474 0.0780392244699145 3 P54709,P05023 2 +Cation transporting atpase complex 0.7101110461718252 2.2948031254077037 0.0217444094613308 0.999999997858474 0.0780392244699145 3 P54709,P05023 2 +Lysosomal lumen 0.4971468172157079 2.276241902164662 0.0228315352554571 0.9999999992197132 0.0809806016091994 37 P04062,Q9NZJ7,Q9UM22,Q8IV08,Q8NHP8,Q9UMR5,P50897,P07602,P17900,O14773,Q9NQ11,Q14108,P13473,P10619,Q13510,O43681,P11117 17 +Organelle envelope lumen 0.4728316280061816 2.259121030801542 0.023875857274316 0.9999999997044784 0.0833818400195345 44 Q9NR28,Q9BRT2,O14925,P05067,Q9Y5J9,Q16891,Q9BPX6,Q9UJZ1,Q96BR5,Q9Y5L4,Q9H078,O00165,O60313,O00584,Q53H12,Q9H4A6,Q8IYU8,Q9Y5J7,O43464,P52888,P50336 21 +Integral component of lysosomal membrane 0.7008617090394154 2.246464661537229 0.0246742606140673 0.9999999998594228 0.0855123230441721 3 Q9NQ11 1 +Neurofilament 0.7209756777060086 2.222351826553594 0.0262595382197039 0.9999999999679048 0.0896378221935758 4 P07196,Q16352 2 +Vacuolar proton transporting v type atpase v0 domain 0.718443045649489 2.2094138617507673 0.0271458677442477 0.999999999985961 0.0916299178876467 4 Q93050,O75787 2 +Proton transporting v type atpase v0 domain 0.718443045649489 2.2094138617507673 0.0271458677442477 0.999999999985961 0.0916299178876467 4 Q93050,O75787 2 +Sec61 translocon complex 0.7173323506751884 2.203733566173389 0.02754308708347 0.9999999999903106 0.0916621827597914 4 Q15041 1 +Translocon complex 0.7173323506751884 2.203733566173389 0.02754308708347 0.9999999999903106 0.0916621827597914 4 Q15041 1 +Cis golgi network 0.659197518160074 2.192187049822112 0.0283660031633132 0.9999999999955078 0.0933200393923495 15 Q8TBA6,P24390,O95249,P49755,Q9Y3A6,O00461 6 +Phagocytic vesicle 0.4646399067082493 2.181795049125034 0.0291246621394096 0.9999999999977898 0.0947856387906236 44 Q93050,O43752,Q03519,P51790,Q9UNK0,P10321,Q15907,Q12846,P08670,Q03518,Q9Y487,O75396,P11279,P30511,P13473,P61026,Q9BZG1 17 +Mhc protein complex 0.7114480239276606 2.1735758876123827 0.0297370008992865 0.9999999999987536 0.0960896683863067 4 P30511,P10321 2 +Mhc class i protein complex 0.7114480239276606 2.1735758876123827 0.0297370008992865 0.9999999999987536 0.0960896683863067 4 P30511,P10321 2 +Derlin 1 retrotranslocation complex 0.7277108902930958 2.165600913016175 0.0303416965652583 0.9999999999992925 0.0970079594410371 5 Q9BUN8,Q9UBV2 2 +Intrinsic component of nuclear inner membrane 0.7342305836411878 2.140736233190317 0.0322953148317326 0.9999999999998866 0.1013039454457285 7 O94901,Q9UH99,Q5SNT2,Q14739,Q9Y2U8 5 +Integral component of synaptic vesicle membrane 0.7397245617810434 2.1358764083700437 0.032689489003963 0.9999999999999216 0.1013039454457285 6 P20020,O60499,O76024,O43752 4 +Azurophil granule 0.4061089046096984 2.121042911167152 0.0339181914605075 0.9999999999999754 0.1035669374409728 69 O15260,O15400,Q92542,Q6IAA8,O43681,O95721,P07602,P11279,P00387,O75131,Q9NZJ7,O00560,Q9NQX7,P17900,P13473,Q8NF37,P10619,Q9H7Z7,Q07065,Q96CS3,Q9H0U3 21 +Protein lipid complex 0.718702755332456 2.1200693704256564 0.0340001955638507 0.9999999999999772 0.1035669374409728 5 Q9BUR5 1 +Ciliary membrane 0.7278108392902474 2.1083740807439737 0.0349986446076167 0.999999999999991 0.1048804267449371 7 Q96J42 1 +Synaptic vesicle membrane 0.6266071087718009 2.096618305385147 0.0360273775191875 0.9999999999999966 0.1065565432815056 16 O43752,P20339,O60499,Q15907,P20020,O43760,O76024,P61020 8 +Pore complex 0.7004548498437518 2.072389012141724 0.038229177243414 0.9999999999999996 0.1112567081314741 10 P05141,P45880,P21796,Q9Y277,P12235 5 +Proton transporting atp synthase complex catalytic core f 1 0.6897826911560042 2.061608038644459 0.0392450680918683 1.0 0.1138483125476564 4 P06576 1 +Myofilament 0.7017543859649152 2.033745948590424 0.0419772167940748 1.0 0.119295992573843 5 P06753,Q9NYL9,P67936,P09493 4 +Striated muscle thin filament 0.7017543859649152 2.033745948590424 0.0419772167940748 1.0 0.119295992573843 5 P06753,Q9NYL9,P67936,P09493 4 +Intrinsic component of synaptic vesicle membrane 0.6871513176515136 2.0015548243954093 0.0453326317937841 1.0 0.1270433014467776 10 O43752,P20339,O60499,P20020,O76024,P61020 6 +Late endosome 0.3930532545820946 1.9699572463703123 0.0488432706567374 1.0 0.1352124687692609 67 O15400,Q9GZP9,P51790,Q96A57,Q9BRK5,Q6IAA8,O43633,P07602,P11279,Q14108,Q9NZJ7,P35670,Q9NQ11,Q9BXS4,P13473,Q9BUN8,Q8IV08,Q9UNK0,O15118,Q9UBQ0,Q9UEU0 21 +External side of plasma membrane 0.4803667071791523 1.9251715034904129 0.0542079058826361 1.0 0.1470917732532763 26 P51790,P00813,O75787,P30511,P11279,Q14118,P55899,O96005 8 +Pigment granule 0.3875714642538444 1.924687697056652 0.0542684405725193 1.0 0.1470917732532763 61 P05556,P08195,Q15758,O43852,P11166,O14773,P35613,P57088,Q92542,P61020,P62820,P27824,P49755,P11279,P07237,P05023,O00560,O75396,P30040,Q93050,P20339,P61019,P55209,P27105 24 +Specific granule 0.4569644379868285 1.9193621123088684 0.0549385223496843 1.0 0.148024267933274 37 Q8NHP6,Q8N2G8,Q4KMQ2,Q08722,P51790,Q12846,Q8WVQ1,Q07065,O14975,O00264,P61225,P27105,P30519,Q6IAA8,Q9Y5K8 15 +Vacuole 0.3593190210469564 1.90623777850979 0.0566193628443965 1.0 0.150763582002088 221 O15260,P04062,P54802,O15400,Q8NCG7,P08195,P51790,Q96A57,P11117,O75787,O14773,Q9Y6I9,Q92542,Q9Y3E7,Q6IAA8,O43633,O43681,O95721,Q9UNK0,Q9Y679,P00813,Q12846,P07602,Q15043,P11279,Q14108,O75131,Q96GC9,O15321,P00387,Q13510,P42892,P56962,Q9NZJ7,O00560,Q96RL7,Q8N511,Q9NQX7,P17900,Q9NQ11,Q9NRA0,Q9NX40,Q9BXS4,O60749,P13473,Q969Q5,P10619,Q8NF37,Q93050,Q9NUN5,Q9UM22,O75503,Q9UHG3,Q9P253,Q8IV08,Q9H7Z7,P50897,Q07065,Q9UMR5,P61019,P30511,Q8NHP8,Q9UEU0,O15118,Q96CS3,P27105,Q15165,Q9H0U3,Q9Y371 69 +Vacuolar lumen 0.3784701494912084 1.7977746421720968 0.0722127273421835 1.0 0.1813749615632439 66 P04062,O14773,O43681,P07602,P00387,Q14108,Q13510,Q9NZJ7,O00560,P17900,Q9NQ11,P13473,P10619,Q9UM22,Q8IV08,Q8NHP8,Q9UMR5,Q9H7Z7,P50897,Q96CS3,P11117 21 +Endosome 0.3505909822841429 1.769570454166104 0.0767987244146184 1.0 0.1900088331566036 229 O15400,Q8N4V1,P05556,Q9GZP9,P51790,Q96A57,P05067,O75787,O14773,P35613,Q9P260,Q9BRK5,Q92542,Q9Y3E7,Q6IAA8,O43633,Q9UID3,O15127,P62820,Q5VW38,Q5VWJ9,Q92544,Q15907,P07602,Q12846,P18031,Q15043,P11279,Q14108,P42892,Q13510,Q92783,Q9NWW5,O00461,Q99805,Q9NZJ7,P35670,Q15057,Q9BZF3,Q96RL7,Q9Y487,O14828,Q9NQ11,Q9H4A6,P30533,Q9NX40,Q9BXS4,O60749,P13473,Q969Q5,P61026,Q12768,P55899,O60831,Q93050,Q9BUN8,Q8IY95,P35232,O43752,P20339,Q8IV08,Q2M389,Q9P253,Q9UNK0,O15118,P10321,P30511,P61225,P36543,Q15904,Q9UBQ0,Q9UEU0,Q9UNH7,Q9UH99 74 +Coated vesicle membrane 0.3716491596495722 1.7356313464049429 0.0826290396878024 1.0 0.2006290010857604 61 P56962,Q15363,Q9NR31,P24390,P49257,Q8N511,P10321,O75396,P49755,Q13190,P30511,Q14108,Q96HR9,Q9UEU0 14 +Dendrite membrane 0.6039956128005597 1.7232698442158652 0.0848397383978574 1.0 0.204335497255317 3 O75787 1 +Cytoplasmic ubiquitin ligase complex 0.6330832665350183 1.6756032550073436 0.0938159308171473 1.0 0.2189842292595624 9 Q6NTF9,Q9BUN8,Q9GZP9,Q9UBV2 4 +Lumenal side of membrane 0.619419501695868 1.6659255687403896 0.0957282402312396 1.0 0.2217378625764427 11 P27824,P51572,Q96DA6,P10321,P30511 5 +Rough endoplasmic reticulum 0.4235032561632888 1.6548612627261214 0.0979526435624411 1.0 0.2225075448029083 39 P56962,Q9HD47,P27824,Q9Y5M8,Q96A33,Q07065,P05067,P49458,P51571,Q15041 10 +Endocytic vesicle 0.368055437494017 1.653337904121332 0.0982621128590299 1.0 0.2225075448029083 86 Q93050,O15400,Q9NUN5,O43752,Q03519,P51790,Q9UNK0,Q15907,P08670,O75396,P30511,P11279,Q14108,P13473,P61026,Q969Q5,Q9BZG1,O00461 18 +Nuclear envelope 0.3452775660534285 1.63517069440641 0.1020132696838562 1.0 0.2291523890571749 188 Q9H1E5,Q86UE4,Q99735,Q14728,P05067,O76062,Q8IWB1,Q9BUP3,Q9NQC3,Q7Z3B4,P57088,Q12981,O43633,Q8IXM6,Q5SNT2,P80303,P42167,P41208,Q9BTX1,Q96KC8,O14657,Q86Y07,Q8N2G8,O00560,O00165,O15173,Q6NUM9,Q15154,Q96S66,Q14739,Q9P035,Q8NFH5,O75844,Q8N6S5,Q8NFQ8,Q9NUQ2,Q9H4L5,O94901,Q15125,O15118,Q9BW91,O14681,P50402,Q9Y2U8,Q96AG4,Q6ZRP7,Q9UH99 47 +Lumenal side of endoplasmic reticulum membrane 0.6311825207728692 1.6350721339078902 0.1020339269718437 1.0 0.2291523890571749 8 P30511,P27824,P51572 3 +Microbody 0.3657702517750872 1.6349743610609149 0.1020544224654587 1.0 0.2291523890571749 57 P40855,P28288,O14734,Q8TB36,Q15067,O75192,P08670,P56589,O43808,Q5T8D3,Q96CN7,P51648,Q9UKU0,Q2T9J0,Q9NR77,Q6IAN0,Q8N4Q0,Q9Y3D6,Q6YN16,Q9BY49,O75381,O00116,Q8NBU5 23 +Photoreceptor connecting cilium 0.6192396582974563 1.6014710134050918 0.1092726351771322 1.0 0.2396607554126475 5 P41208 1 +Endosome membrane 0.3343821247094661 1.5862116657096972 0.1126913023596527 1.0 0.2455343624129214 136 O15400,Q8N4V1,P05556,P51790,O75787,Q92542,Q9Y3E7,Q6IAA8,O43633,O15127,Q5VWJ9,Q15907,Q15043,P11279,Q14108,P42892,Q92783,O00461,Q99805,Q15057,Q9BZF3,Q96RL7,Q9Y487,Q9NQ11,Q9BXS4,O60749,P13473,P61026,P55899,O60831,Q93050,Q8IV08,Q9P253,Q9UNK0,O15118,P10321,P30511,P61225,Q15904,Q9UBQ0,Q9UEU0,Q9UNH7,Q9UH99 43 +Hulc complex 0.5585743499853962 1.586141028242697 0.1127073216179752 1.0 0.2455343624129214 2 O75150 1 +Sperm midpiece 0.6153827987775404 1.5808030891571954 0.1139230680020453 1.0 0.2468786294650528 5 Q15388 1 +Multivesicular body membrane 0.6228248832116681 1.562282161484296 0.1182215324771709 1.0 0.2531725270973377 7 Q9NQ11,O43633 2 +Platelet alpha granule 0.5179049439140402 1.5570315575430764 0.1194629931391668 1.0 0.2537998507802167 18 Q9NTK5,Q8NBM8,P05067,Q9UEU0,Q9Y6I9,Q6UXV4,Q96JJ7 7 +Microtubule organizing center attachment site 0.593598707239855 1.5472636017615964 0.1217996948386344 1.0 0.2560049141515741 4 O94901 1 +Recycling endosome membrane 0.4300918929482681 1.5267690195762456 0.1268184578357358 1.0 0.2617071811701095 28 O15127,P10321,Q15907,P30511,P61026,Q9UEU0 6 +Transcription preinitiation complex 0.5628287551139564 1.491979065795905 0.1357046334078531 1.0 0.2744316417245671 3 P29083,Q00403 2 +Photoreceptor inner segment 0.6129520668448933 1.484219583295992 0.137750676109287 1.0 0.2759618632184065 6 Q96HR9,P35613 2 +Dynactin complex 0.5953697820118454 1.4729617304905265 0.1407613551809152 1.0 0.2790639967342163 5 O75935 1 +Postsynaptic endocytic zone 0.5372480280455777 1.4617070401588406 0.1438215071993753 1.0 0.2814438115022259 2 P09496 1 +Meiotic spindle 0.530820917323999 1.4239597081561486 0.154458135966826 1.0 0.2916606207455517 2 P54652 1 +Chromosome passenger complex 0.5308209173239894 1.4239597081560915 0.1544581359668424 1.0 0.2916606207455517 2 Q53HL2 1 +Sarcoplasmic reticulum membrane 0.5853183016525497 1.412388366638353 0.1578356399532323 1.0 0.2937166549129447 9 O75298 1 +Membrane microdomain 0.346873526016888 1.4045579928806364 0.1601527553639155 1.0 0.2942067094197116 67 P05556,P05067,O14773,P35613,Q6IAA8,P09601,Q14118,P21796,Q9NWW5,P05023,Q9HD47,O00560,P05141,O94905,P13473,P78310,O15118,P50897,P61225,P27105 20 +Ikappab kinase complex 0.5473407364114433 1.403767754744088 0.160388018901715 1.0 0.2942067094197116 3 O15111,Q8IUD2 2 +Endocytic vesicle membrane 0.3870587226264471 1.3923112407546094 0.1638281690711733 1.0 0.2999112449931964 43 Q93050,Q03519,P10321,Q12846,Q15907,Q03518,Q9Y487,O75396,P30511,P11279,Q14108,P13473,P61026,Q9BZG1 14 +Nuclear membrane 0.3354221509282694 1.3803327015514688 0.1674842306766233 1.0 0.3047608846781042 115 Q9H1E5,Q86UE4,Q14728,O76062,Q8IWB1,Q7Z3B4,Q9NRG9,P11802,Q8N1F7,Q8IXM6,Q8TEM1,Q5SNT2,Q9BTX1,Q9BW27,Q96KC8,O14657,O00560,O00165,Q9BZF3,Q13185,Q6NUM9,Q15154,Q96S66,Q14739,Q9P035,Q8NFH5,O75844,Q8N6S5,Q9BTV4,Q8NFQ8,Q9H4L5,O94901,Q9BW91,O14681,P50402,Q9Y2U8,Q6ZRP7,Q9UH99,P02545 39 +Platelet alpha granule lumen 0.5515689113184058 1.3786825891199337 0.1679926399517646 1.0 0.3048933455723639 13 Q9NTK5,Q8NBM8,P05067,Q9UEU0,Q9Y6I9,Q6UXV4 6 +Early phagosome 0.5382817066043117 1.3519095349806034 0.1764042569135191 1.0 0.3140535116045174 3 O60493,P20339 2 +Smooth endoplasmic reticulum 0.5621231130804888 1.339267795305962 0.1804835088752636 1.0 0.318219011252762 11 P56962,P27824,O00264 3 +Intrinsic component of presynaptic membrane 0.5678889690887594 1.323401180680826 0.1857019993710713 1.0 0.3248890470692346 5 Q92542,P27824 2 +Glial cell projection 0.552654730726148 1.3206757308489547 0.1866095095739584 1.0 0.3258489128714504 4 P05067 1 +Rough endoplasmic reticulum membrane 0.4910420040708781 1.3136258156914982 0.188972156742009 1.0 0.3287101883558318 17 Q96A33,P51571,Q15041,Q9Y5M8 4 +Escrt iii complex 0.56507774987008 1.308016990169231 0.1908675466184834 1.0 0.3303529008929401 5 O43633 1 +Copi coated vesicle 0.5278650355926119 1.3076029674825669 0.1910080098775259 1.0 0.3303529008929401 14 P49755,Q15363,Q8N511,P24390 4 +Nucleoid 0.3967748403030471 1.2949270253459488 0.195345404586658 1.0 0.3327366874971206 33 Q9NVI7,Q9BRT2,P05141,P45880,P06576,Q96AG4,P21796 7 +Secretory vesicle 0.3170205057703233 1.293349099997608 0.19589034597647 1.0 0.3327366874971206 270 O15260,O15400,Q4KMQ2,Q8NBM8,P51790,Q96A57,P05067,O75787,P35613,O43760,O76024,Q9Y6I9,Q92542,P14174,Q6IAA8,O43681,Q15363,O95721,Q15907,P07602,P45880,P49755,Q8WVQ1,P11279,O75131,P00387,P42892,Q9BT78,P20340,P30519,Q6UXV4,Q13510,Q8N2G8,Q9NZJ7,Q9NTK5,Q08722,O00560,Q96RL7,Q5T9A4,O60499,Q9NQX7,P17900,O00264,Q8NBX0,P13473,P61026,Q969Q5,Q8NF37,P78310,Q93050,Q92520,O43752,Q9H7Z7,P50897,Q07065,P10321,Q96CS3,O00231,P61225,Q9UEU0,Q96JJ7,Q9H0U3 62 +Presynapse 0.3388322998847523 1.2928851000719228 0.1960508015539201 1.0 0.3327366874971206 98 O15400,Q96A49,Q99623,Q96A57,P51790,P05067,P11166,Q14141,O43760,O76024,Q92542,Q9Y639,P61020,Q8IUD2,P07196,O95721,P27824,Q15907,Q12846,Q9BVK6,P11279,Q9BT78,O60645,O60499,P61026,Q13641,O43752,P20339,Q9P253,P50897,Q5EBL8,Q9UEU0 32 +Early endosome membrane 0.3584635180102536 1.2853163443892457 0.1986817609526543 1.0 0.3356718912370072 50 O15400,Q8N4V1,P04439,P51790,P61020,O95219,Q9Y5X3,Q5VWJ9,Q15043,Q92783,Q9BZF3,O60749,P20339,Q8IV08,Q86YV9,Q86Y82,P10321,P30511,Q9UEU0,Q9UNH7 20 +Trans golgi network membrane 0.3935288597311565 1.2389057221477544 0.2153804143343152 1.0 0.3497714775995523 31 O15127,Q9H9E3,P35670,O43752,O60499,P05067,Q9NX62,P20340,Q9UID3 9 +Side of membrane 0.3352791470950196 1.2194531949418648 0.2226722303564459 1.0 0.356589744556707 79 Q96A49,P05556,Q9NR28,P04439,P51790,O75787,Q9NV70,Q8TCT9,P29992,P27824,P08183,P00813,P20020,P18031,P11279,Q14118,P07237,P42892,P51572,P63218,P17900,P10619,O96005,P55899,Q9H0H5,P20339,O43464,Q96DA6,A0FGR8,P10321,P30511,Q9BSJ8 32 +Chloride channel complex 0.5486752888359696 1.217995265158626 0.2232257720451422 1.0 0.3568468327763894 5 Q96S66,Q9C0H2 2 +Cell surface 0.3348937746992845 1.2098041535090802 0.2263540520686138 1.0 0.3590642227039457 86 Q4KMQ2,Q99623,P51790,P05067,O75787,Q9Y639,O75298,P00813,P11279,Q14118,P42892,Q08722,O15258,P55899,O96005,Q13641,P35232,P10321,P30511,P06576,Q96JJ7 21 +Endoplasmic reticulum quality control compartment 0.5616947471649218 1.2096906229155815 0.2263976293795182 1.0 0.3590642227039457 6 Q9BUN8,P27824,Q9UKV5 3 +Growth cone membrane 0.4945953841659365 1.2094298904446985 0.2264977309632065 1.0 0.3590642227039457 2 Q9UPT5 1 +Extrinsic component of mitochondrial inner membrane 0.5416765724830247 1.1794672083678663 0.2382121867380129 1.0 0.3735693705666938 5 Q96BW9,Q96D53 2 +Early endosome 0.3271241998851223 1.169091238827983 0.2423668733911688 1.0 0.3768306867109268 106 O15400,Q8N4V1,Q9GZP9,P51790,Q96A57,P05067,Q92542,P62820,Q5VW38,Q5VWJ9,Q92544,P18031,Q15043,Q13510,Q92783,Q9NWW5,Q9BZF3,O60749,Q12768,Q9BUN8,P35232,O43752,Q8IV08,Q9P253,Q9UNK0,P10321,P30511,Q9UBQ0,Q9UEU0,Q9UNH7 30 +Bleb 0.5386846365356186 1.1629789393568062 0.2448380473892992 1.0 0.3793736297431463 5 Q9BRK5 1 +Nuclear pore nuclear basket 0.5443798288707289 1.136510499412679 0.2557429739072865 1.0 0.3911772971760526 7 P41208 1 +Sarcoplasm 0.4559399903199586 1.1258273182231062 0.2602386185904155 1.0 0.3964709155706331 18 P16615,O75298,O43852,O00165 4 +External encapsulating structure 0.3707474479163536 1.0944975574804836 0.2737368180353647 1.0 0.4135657750018489 36 Q9NZJ7,P49257,P07602,Q53GQ0,P84157 5 +Caspase complex 0.5393871631125864 1.089006455610738 0.2761510388882175 1.0 0.4165201716121288 6 Q9H490,Q96S52,O43292 3 +Late endosome membrane 0.3645542877084046 1.0661545263925696 0.2863537944835783 1.0 0.4304788830978297 38 Q8IV08,P51790,Q9P253,Q9UNK0,O15118,Q9NQ11,Q15043,P11279,Q14108,Q9BXS4,P13473,Q9UEU0,Q6IAA8,O43633 14 +Proton transporting v type atpase complex 0.5092760184622652 1.0588074939789076 0.2896874600428298 1.0 0.4340531579519629 12 Q93050,Q8N511,Q9Y487,O75787,P36543,Q15904 6 +Brush border membrane 0.5250473005640771 1.0509399655529332 0.2932861634227048 1.0 0.4352772593626139 8 P40855 1 +Amphisome membrane 0.5322388292391327 1.0502566715816308 0.2936001202283225 1.0 0.4352772593626139 6 O43633 1 +Amphisome 0.5322388292391327 1.0502566715816308 0.2936001202283225 1.0 0.4352772593626139 6 O43633 1 +Golgi lumen 0.5285816020283591 1.049691249759824 0.2938600880939233 1.0 0.4352772593626139 7 Q9BRK5,Q9NX62,Q14118,O00461 4 +Trans golgi network 0.3177786560852779 1.0183978186828933 0.3084889384132125 1.0 0.4517338576476123 70 P04062,Q96A57,P05067,Q9P260,Q9UID3,O15127,Q96ED9,Q12846,Q9NX62,P20340,P35670,O60499,Q9H4A6,P61026,Q9H9E3,O43752,Q9UNK0,P98194,Q9BSR8 19 +Tor complex 0.4618755477651184 1.0139974080925849 0.3105839890670527 1.0 0.4519395225526985 2 Q9Y4R8 1 +Torc1 complex 0.4618755477651184 1.0139974080925849 0.3105839890670527 1.0 0.4519395225526985 2 Q9Y4R8 1 +Clathrin coated vesicle 0.3313262348487358 1.011017745010181 0.3120079367814665 1.0 0.4528760695029218 51 Q5VW38,Q9NUN5,P51572,O00165,P49755,Q14108,P42892,Q96HR9 8 +Mitochondrial alpha ketoglutarate dehydrogenase complex 0.510420306306868 1.0068892879285865 0.3139879802734451 1.0 0.4547066763768551 5 P12694,O14874,P11182 3 +Anchored component of synaptic vesicle membrane 0.4963324625780648 1.0043780291819089 0.3151964359485224 1.0 0.4557298787281184 4 P61020,P20339 2 +Lsm2 8 complex 0.50886761760109 0.998307274305282 0.3181303813117326 1.0 0.459240677632835 5 Q9Y4Y9,P62312 2 +Cuticular plate 0.4554484370435402 0.9755625699804098 0.3292812807150991 1.0 0.4715889635478075 2 Q9Y5X1 1 +Collagen containing extracellular matrix 0.3633516478252528 0.963497642405592 0.3352978467236871 1.0 0.4789967043681407 31 P49257,Q9NZJ7,P84157,P07602 4 +Presynaptic active zone membrane 0.5020811776936486 0.9608036630249 0.3366508964617178 1.0 0.4795558856737504 5 Q9Y639,P27824,Q12846 3 +Wash complex 0.5007976502173374 0.9537125524470216 0.3402291645100972 1.0 0.483455526408714 5 Q2M389,Q12768 2 +Integral component of presynaptic active zone membrane 0.4846436813563013 0.93853557113322 0.3479692455949594 1.0 0.4911901728648098 4 P27824 1 +Intrinsic component of presynaptic active zone membrane 0.4846436813563013 0.93853557113322 0.3479692455949594 1.0 0.4911901728648098 4 P27824 1 +Copi coated vesicle membrane 0.4884503376241538 0.935127156277021 0.349722772997447 1.0 0.4915608016744302 12 Q15363,Q8N511,P24390 3 +Ciliary transition zone 0.5008946285294719 0.916163371030416 0.359581214026091 1.0 0.5015357025125816 8 Q15154,P41208 2 +Paraspeckles 0.5015283591890489 0.8838091963293072 0.3767992211780329 1.0 0.5183843830752332 6 P23246,Q8WXF1 2 +Secretory granule 0.3003576747010766 0.8435672403575496 0.3989112768933907 1.0 0.5417441778895544 242 O15260,O15400,Q4KMQ2,Q8NBM8,P51790,P05067,O75787,P35613,O76024,Q9Y6I9,Q92542,P14174,Q6IAA8,O43681,Q15363,O95721,Q8WVQ1,P07602,P45880,P49755,P11279,O75131,P00387,P42892,P20340,P30519,Q6UXV4,Q13510,Q8N2G8,Q9NZJ7,Q9NTK5,Q08722,O00560,Q96RL7,Q5T9A4,Q9NQX7,P17900,O00264,Q8NBX0,P13473,P61026,Q969Q5,Q8NF37,P78310,Q93050,Q92520,Q9H7Z7,P10321,Q07065,Q96CS3,O00231,P61225,Q9UEU0,Q96JJ7,Q9H0U3 55 +Postsynaptic density membrane 0.4905312511149479 0.8406153767288448 0.4005634415896764 1.0 0.5417441778895544 7 P57105 1 +Basolateral plasma membrane 0.3186587460985502 0.8392044403987038 0.4013545959721969 1.0 0.5417441778895544 50 Q99808,P08195,P11166,P35613,Q12846,P20020,Q15043,Q14118,P05023,P30825,P35670,P60033,P57105,Q9Y6M7,P55011,P78310,P54709,Q5EBL8,Q14254 19 +Escrt complex 0.4836721647035455 0.8392019608635181 0.4013559871472596 1.0 0.5417441778895544 9 Q9H9H4,Q9BRG1,Q9Y3E7,Q92783,O43633 5 +Endoplasmic reticulum exit site 0.4122849163300909 0.8177890280399648 0.4134776641906725 1.0 0.552114292772251 18 Q96PC5,Q9Y3A6 2 +Cell pole 0.4401429303762775 0.7844862567298437 0.4327548429780594 1.0 0.5719275367649392 3 P08195 1 +Rpap3 r2tp prefoldin like complex 0.4751359544347745 0.7729929216516099 0.4395265697465553 1.0 0.5783914859853221 8 O15212,Q9NUG6 2 +Eukaryotic translation initiation factor 2b complex 0.4803045025441494 0.76934964905454 0.4416857706267869 1.0 0.5803917217498156 6 P49770 1 +Golgi associated vesicle 0.3416754975267979 0.7649217232418908 0.4443181575007875 1.0 0.582165782122244 31 Q15363,P24390,Q8N511,Q9Y3B3,P49755 5 +9plus0 non motile cilium 0.4609538779086921 0.7300106357636547 0.4653836834652338 1.0 0.5951985439425792 10 P41208,P35613 2 +Endosome lumen 0.4424306528959877 0.7023999482454747 0.4824297775729116 1.0 0.6143706003312815 4 P30533,P05067 2 +Mhc class i peptide loading complex 0.4528748658459223 0.6907212041911643 0.4897407613589117 1.0 0.6219365193201285 5 Q03518,Q03519 2 +T tubule 0.4597971267604372 0.673403621404374 0.5006905453440156 1.0 0.6331852579002314 7 O75298 1 +Nuclear outer membrane 0.4431108404895192 0.6676094251360392 0.504382939800132 1.0 0.6352007064334534 12 P50402,Q6NUM9 2 +Basal part of cell 0.2821684805679274 0.6112875787249983 0.5410092127180364 1.0 0.6738496092564843 57 Q99808,P08195,Q15758,P11166,P35613,Q12846,P20020,Q15043,Q14118,P05023,P30825,P35670,P60033,P57105,Q9Y6M7,P55011,P42785,P78310,P54709,Q5EBL8,Q14254 21 +Cell division site 0.3265283647220057 0.6035263742753131 0.546158575527429 1.0 0.677475391501237 26 Q96RT7 1 +Postsynaptic specialization membrane 0.4341397978262722 0.5790151085778891 0.5625789786942001 1.0 0.6902275298875887 10 P57105,P52292 2 +Semaphorin receptor complex 0.4035651665692604 0.576963668462751 0.5639639988682981 1.0 0.6902275298875887 3 Q9UIW2,O14786 2 +Intermediate filament 0.3633810573299694 0.5621300932354724 0.5740273863552552 1.0 0.6986615072430342 20 O75298,P48681,Q03252,Q16352,P08670,P02545,P07196 7 +Tertiary granule 0.3036698514594245 0.5341420819926228 0.5932432367243776 1.0 0.7153583784139906 43 Q93050,O15400,Q4KMQ2,Q08722,Q5T9A4,Q8WVQ1,O75787,P11279,P61225,P13473,Q13510 11 +Presynaptic membrane 0.3641795140142537 0.52417311759426 0.6001581366301727 1.0 0.7198726394454383 19 O60645,Q96A49,P27824,Q12846,P20020,Q92542,Q9Y639,Q8IUD2 8 +Phagophore assembly site 0.4275831083678827 0.5023661720939955 0.6154099698802737 1.0 0.7294938024168258 7 Q96GC9,Q86Y82,Q9H0U4 3 +Dihydrolipoyl dehydrogenase complex 0.4269004175363995 0.4988121909917808 0.617911698400381 1.0 0.7314232075380375 7 P12694,O14874,P11182 3 +Mitotic spindle microtubule 0.4261008916267075 0.4946544947461699 0.6208440281152505 1.0 0.7314232075380375 7 Q96CS2,Q9H6D7,O94927 3 +Cd40 receptor complex 0.4016692592117064 0.4812988523954059 0.6303041125786073 1.0 0.737520791522391 4 Q9NR28 1 +Oxoglutarate dehydrogenase complex 0.3854471069549973 0.4772829954802648 0.6331606179738083 1.0 0.7389586646789433 3 P09622,P36957 2 +9plus2 motile cilium 0.3307322978861627 0.4632039512997636 0.643218184264053 1.0 0.7471810478267218 23 Q96RL7,P41208,Q15388 3 +Caveola 0.3834933521905296 0.4616668866672649 0.6443202207580652 1.0 0.7471810478267218 15 P09601 1 +Lamin filament 0.3771994280701979 0.4329056276389266 0.6650833314399895 1.0 0.7634584891877503 3 P02545 1 +Sarcolemma 0.3048955548850352 0.4212136601697502 0.6735990703301253 1.0 0.7703122869770199 27 O75298,P35613,P11279,Q14118,Q92542 5 +Presynaptic active zone 0.3665309327641886 0.4084560961509679 0.6829388568637229 1.0 0.7765864329231993 16 P27824,Q99623,Q12846,P05067,P20020,Q9Y639,Q8IUD2 7 +Peptidase complex 0.2651944266736625 0.3941703241871916 0.6934552936506584 1.0 0.7847212872844497 62 Q05086,P61289,Q96S52,Q9H490,O00231,P67812,O43292,Q9UL46,P49721,Q15005 10 +Apical plasma membrane 0.2816037692512417 0.3855287161061889 0.6998457352284504 1.0 0.7864603064200902 48 Q99808,Q86UE4,P08195,P51790,O75787,P11166,Q9NV70,Q9NP72,Q99797,P33527,P08183,P20020,Q15043,P05023,P30825,O00165,Q9Y6M7,P21281,P55011,P05026,P54709,Q16181,P36543,Q14254,Q16625 25 +Golgi associated vesicle membrane 0.3373090038754139 0.3777549149426838 0.705612668901304 1.0 0.7919608199782251 20 Q8N511,P24390 2 +Mcm complex 0.4021643755483941 0.3646941475005804 0.7153397277882134 1.0 0.7999119123543077 6 P33991,P33993,Q14566,P49736,P33992 5 +Retromer complex 0.3941256998212916 0.3514346727019858 0.7252622741310808 1.0 0.8063416304938028 9 O60749,Q9UBQ0 2 +Cell tip 0.3461875547765059 0.3464163501950588 0.729029839248728 1.0 0.8082528620730709 2 Q9BTU6 1 +Sperm connecting piece 0.3450189891907608 0.3402654048896064 0.7336566673401639 1.0 0.8123905535913034 2 P10644 1 +Cytoplasmic microtubule 0.3367733471887552 0.3373564809563462 0.7358481868386075 1.0 0.8138247912904454 19 Q6NUK4,Q9Y5M8 2 +Ficolin 1 rich granule membrane 0.3399906906824896 0.3249477727620064 0.7452205996741319 1.0 0.8207959083564698 18 Q93050,Q5T9A4,O75787,P11279,P13473 5 +Tubular endosome 0.3704049401779277 0.3213449205910133 0.747949018300972 1.0 0.822200615759422 4 Q9Y5X3,Q9UNH7 2 +Cul4a ring e3 ubiquitin ligase complex 0.3533021624780815 0.3089378815078734 0.7573687800726414 1.0 0.8305445076158918 3 Q92990,Q13619 2 +Dendrite terminus 0.3671441099093846 0.3053581449807038 0.7600933958382057 1.0 0.8306285310784458 4 Q7L576,P07900,Q9Y366 3 +Gtpase complex 0.3783625730994187 0.3052315983312117 0.7601897679803837 1.0 0.8306285310784458 5 P29992,P63218,Q14344,P08754 4 +Photoreceptor outer segment 0.3756096617795855 0.2920694045593229 0.7702335588908291 1.0 0.8397467176886949 5 P35613,Q15555 2 +Proton transporting two sector atpase complex catalytic domain 0.3782004174898187 0.2918721489401457 0.7703843786725582 1.0 0.8397467176886949 11 Q15904,P36543,P36542,P06576 4 +Neuron projection membrane 0.3811168503224731 0.286213866613895 0.774714323780815 1.0 0.8427260429852923 9 O75787,Q12846 2 +Intermediate filament cytoskeleton 0.2869978656573467 0.2858750300896163 0.7749738390888976 1.0 0.8427260429852923 33 Q3SXM5,O75298,Q16352,P08670 4 +Hippocampal mossy fiber to ca3 synapse 0.3451198129748651 0.2683987348389852 0.7883924132517264 1.0 0.8522146562292471 3 P63104,O60716 2 +Non motile cilium 0.3424060733419504 0.262380086124295 0.7930284239950802 1.0 0.8541753368772631 16 Q15154,P35613,P41208 3 +Ccr4 not complex 0.3740925294020318 0.2380844486578646 0.8118155961539566 1.0 0.8715193069858697 7 O95628 1 +Oligosaccharyltransferase complex 0.3716909633148118 0.233182517648705 0.8156196805993337 1.0 0.8738193752558167 8 Q9H0U3 1 +Perinuclear endoplasmic reticulum 0.3734586932622495 0.2299851660555049 0.8181032965585902 1.0 0.8749561758247348 6 Q8N5K1,Q9H4L5,P51572 3 +Tertiary granule membrane 0.3569055758740119 0.2267888990565225 0.8205878960884869 1.0 0.876580952527466 13 O75787,Q4KMQ2,P61225,Q08722 4 +Multivesicular body 0.3509906037947611 0.1964566807028724 0.8442527357160345 1.0 0.8997435258569946 13 Q9NQ11,Q9Y3E7,P11279,O43633 4 +Anaphase promoting complex 0.3567892209330141 0.1710674744487938 0.8641707104754688 1.0 0.918813823315838 9 Q96DE5,O60566 2 +Exocyst 0.3570443859641468 0.1666205703419339 0.8676686071673474 1.0 0.9214539126408788 8 O60645,Q96KP1,Q8IYI6,Q9NV70 4 +Plasma membrane raft 0.2885101109542927 0.1557749014856782 0.8762104548017766 1.0 0.9294381927102956 23 Q9HD47,P09601 2 +Chromocenter 0.3341128325051133 0.1532668482992608 0.878187842976758 1.0 0.930448729781676 4 Q53HL2,P83916,P45973 3 +Proteasome core complex beta subunit complex 0.3529060197007019 0.1444260438483739 0.8851640523835982 1.0 0.9367470391192392 7 P49721 1 +U6 snrnp 0.3527758709296942 0.14076526817101 0.8880553817895949 1.0 0.9385022047167888 6 Q9Y4Y9,P62312 2 +Immunological synapse 0.3335216761171735 0.1397092047946165 0.8888897533661215 1.0 0.9385022047167888 14 O15400,P60033,P20020,Q9UJZ1,Q9Y639 5 +Calcium channel complex 0.3453415288389786 0.1163059617368656 0.9074100608978796 1.0 0.9569434788563004 8 Q9NWR8,Q8IYU8 2 +Postsynaptic membrane 0.2620437289552744 0.0866605565715736 0.930941329713943 1.0 0.9783503789123384 36 P27824,P57105,P51790,O75787,Q8NBU5,Q14118,P52292,Q9Y639 8 +Neuromuscular junction 0.2993546005404113 0.0824140864306454 0.9343174348038156 1.0 0.9807632726033114 18 P57105,O43760,P07196,P05067 4 +Postsynaptic specialization intracellular component 0.3154048523823418 0.0767817044222724 0.9387972055221652 1.0 0.9820597495554448 4 P50570,Q9UQB8,O60716 3 +Postsynaptic density intracellular component 0.3154048523823418 0.0767817044222724 0.9387972055221652 1.0 0.9820597495554448 4 P50570,Q9UQB8,O60716 3 +Neurofibrillary tangle 0.2874671340928953 0.0706388603219913 0.9436851815823613 1.0 0.9860369906522256 2 P07197 1 +Ciliary basal body 0.2592230463452479 0.0658491311809732 0.947497940061709 1.0 0.9888829075586572 26 O75665,Q9Y366,Q15154,O43805,P41208 5 +Apical part of cell 0.2369547778536525 0.0404251658065765 0.9677541672320468 1.0 1.0 63 Q99808,Q86UE4,P08195,P51790,P05067,O75787,P11166,Q9NV70,Q9NP72,Q99797,P33527,P20020,Q15043,P41208,P05023,P30825,O00165,Q9Y6M7,Q15154,P55011,P54709,Q16181,P36543,Q14254 24 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9483313659c9f54b24914c030332b395c3a797ea --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atg1 ulk1 kinase complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Connexin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystroglycan complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD13", "ABHD6", "ABI2", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG5", "ALG6", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC1", "ARMC10", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCKDK", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf57", "C12orf73", "C14orf2", "C19orf70", "C1QBP", "C1orf35", "C2orf49", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARS2", "CASK", "CASP3", "CAST", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC86", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CD81", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPH", "CENPI", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTB", "CLTC", "CMC2", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "CNTLN", "COA1", "COA3", "COA7", "COASY", "COG4", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1C", "CORO7", "COTL1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRCP", "CRK", "CRKL", "CRMP1", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC2", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "ENPP4", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM210A", "FAM210B", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTB", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GJC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMPR2", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPX8", "GRAMD4", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK2", "HP1BP3", "HPF1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS4", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ITCH", "ITGA6", "ITGB1", "ITM2C", "ITPRIP", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRWD1", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED17", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METTL13", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS2", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NENF", "NES", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NME1", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OFD1", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACS1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PAXIP1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD11", "PECR", "PEF1", "PELP1", "PES1", "PEX11A", "PEX11B", "PEX14", "PEX19", "PEX3", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF5A", "PHF6", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPFIBP1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPM1L", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAI", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPOUT1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUFU", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARDBP", "TARS2", "TBC1D10A", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSR1", "TTC1", "TTC19", "TTC26", "TTC37", "TTF1", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TXNRD2", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBAC1", "UBAC2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCR11", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "USMG5", "USO1", "USP10", "USP14", "USP15", "USP19", "USP22", "USP28", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UST", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WTAP", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABHD10", "ABHD12", "ACAP2", "ACAT2", "ACBD5", "ACOT8", "ACOX1", "ACP2", "ACP6", "ACSL6", "ADA", "ADPGK", "AGK", "AGPAT5", "AGPS", "AGTRAP", "AHSA1", "ALDH3A2", "ALG1", "ALG11", "ALG5", "AMFR", "ANAPC16", "ANKLE2", "ANO6", "APOL2", "APOO", "APOOL", "APP", "ARFGAP2", "ARL6IP1", "ARL6IP6", "ARMC10", "ASAH1", "ASNA1", "ATAD1", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP7B", "AUP1", "B3GALT6", "BAIAP2", "BCAP29", "BCAP31", "BCKDHA", "BCKDK", "BCL2L13", "BCS1L", "BET1", "BNIP1", "BRI3BP", "BSG", "BUB1B", "C12orf73", "C19orf70", "CALU", "CAMLG", "CANT1", "CANX", "CARS2", "CBX1", "CBX3", "CBX5", "CCDC134", "CCDC47", "CCDC51", "CD47", "CD81", "CDCA8", "CDIPT", "CDK4", "CDKAL1", "CDS2", "CERS1", "CERS2", "CETN2", "CHCHD3", "CHMP2A", "CHMP3", "CHPF2", "CHST14", "CHUK", "CISD1", "CISD2", "CKAP4", "CLCC1", "CLCN3", "CLN5", "CLN6", "CLPB", "CLPP", "CLPTM1", "CLTA", "CMC2", "CNOT4", "CNPY2", "COA1", "COA3", "COA7", "COG4", "COPS4", "COQ8A", "COQ8B", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "CPNE3", "CPT1A", "CPT2", "CRTAP", "CTNND1", "CTSA", "CTSC", "CUL4A", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAG1", "DAGLB", "DBT", "DCTN3", "DDRGK1", "DERL1", "DERL2", "DHCR24", "DHFR", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DIABLO", "DLD", "DLST", "DNAJC1", "DNAJC11", "DNAJC19", "DNM2", "DOLPP1", "EBP", "ECE1", "EI24", "EIF2B2", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EPDR1", "ERAP1", "ERC1", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ERP29", "ERP44", "ESYT1", "ESYT2", "EXOC1", "EXOC2", "EXOC3", "EXOC7", "EXOC8", "EXOG", "FADS2", "FAF2", "FAM162A", "FAM210A", "FAM210B", "FAM3C", "FAM8A1", "FCGRT", "FDFT1", "FECH", "FIS1", "FKBP14", "FKBP7", "FKBP9", "FLOT2", "FOXRED1", "FUNDC2", "FUT8", "GADD45GIP1", "GALNT1", "GBA", "GDAP1", "GDPD1", "GHDC", "GHITM", "GJC1", "GLG1", "GLMN", "GLOD4", "GLT8D1", "GM2A", "GNA11", "GNA13", "GNAI3", "GNG5", "GOLGA5", "GOLIM4", "GOLPH3", "GOLT1B", "GOSR1", "GPAA1", "GPAT4", "GPR107", "GPX8", "GRAMD4", "GTF2B", "GTF2E1", "HACD2", "HACD3", "HAUS1", "HAUS4", "HAUS5", "HAX1", "HCCS", "HIGD1A", "HK2", "HLA-A", "HLA-C", "HLA-F", "HM13", "HMOX1", "HMOX2", "HOOK2", "HPS6", "HS2ST1", "HSD17B11", "HSD17B12", "HSDL1", "HSDL2", "HSP90AA1", "HSPA13", "HSPA2", "HTATIP2", "HTRA2", "ICMT", "IER3IP1", "IFT52", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "INA", "ISOC1", "ITGB1", "ITM2C", "ITPRIP", "JAGN1", "KDELR1", "KIAA0319L", "KIAA1468", "KIF20A", "KPNA2", "LAMP1", "LAMP2", "LAMTOR1", "LBR", "LCLAT1", "LDAH", "LEMD3", "LETM1", "LMAN1", "LMBRD1", "LMNA", "LMNB2", "LPCAT1", "LPCAT4", "LPGAT1", "LRPAP1", "LRRC59", "LSM5", "LSM6", "LYSMD3", "MAGT1", "MAIP1", "MAN1A2", "MAPRE2", "MBLAC2", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MCUB", "MCUR1", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MIPEP", "MMGT1", "MOSPD2", "MPV17L2", "MRPL10", "MRPL12", "MRPL40", "MRPL45", "MRPL50", "MRPS12", "MRPS26", "MSMO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MTX2", "MTX3", "MXRA7", "NAGLU", "NAP1L1", "NCLN", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFA6", "NDUFAF1", "NDUFAF2", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NEFL", "NEFM", "NES", "NNT", "NPC1", "NPTN", "NRM", "NRP1", "NSDHL", "NUCB1", "NUCB2", "NUDT9", "NUP210", "NUP35", "NUP54", "NUP85", "NUP93", "OCIAD1", "OCLN", "OFD1", "OLA1", "OPA1", "OPA3", 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0.0990971562045587 0.0067573778891409 0.0105162900829293 5.72440703832187e-09 +Inorganic molecular entity transmembrane transporter activity 49 87 4.374215954194338 1.218696907723249e-05 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 1.3511915191681681e-08 0.0059885984942463 0.0001094203271441 0.0002751387625742 1.6757164339864335e-09 +Active transmembrane transporter activity 54 85 4.266885855623991 1.982205127704084e-05 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 3.020468714564605e-08 0.2533252671947448 0.0032633994856491 0.0003948716545347 2.5708114339532923e-09 +Primary active transmembrane transporter activity 26 63 4.055434329398959 5.004123071628008e-05 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 1.6903124067850733e-08 0.1131277718078383 0.0001498589333904 3.2521513425213215e-05 4.3998496851949185e-10 +Proton transmembrane transporter activity 18 39 3.879318154727281 0.0001047496749806 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 2.2413792580624295e-08 0.0490886173861251 7.389910731518841e-05 6.954749025761443e-05 1.3765755538670731e-09 +Active ion transmembrane transporter activity 32 47 3.69068026808497 0.0002236551212155 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 2.1564150277678545e-05 0.4354616437047781 0.0267992171546872 0.066807830876721 3.616084518255329e-06 +Anion transmembrane transporter activity 38 49 3.6295742413416527 0.0002838890752123 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 8.67203229058218e-07 0.1225807784723296 0.1209939299005533 0.000235412956108 2.525769241345924e-06 +Organic anion transmembrane transporter activity 27 34 3.500637146066752 0.0004641473444766 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.0001068810418734 1.0 1.0 0.0169357854376417 0.0002122388464955 +Oxidoreduction driven active transmembrane transporter activity 15 38 3.369455351642216 0.0007531689203341 9.733009708737864 29.83252427184466 0.7626445826297276 0.3795490924215395 4.629116134249794 3.4519743101246267 1.4198222355288384 0.35536187545778 4.969602027654944e-07 0.0356328568827733 1.949284152634766e-06 1.6435639860610823e-05 2.5764199769426418e-08 +Passive transmembrane transporter activity 16 36 3.344323647558119 0.0008248345124604 10.728155339805824 34.00242718446602 0.8598494327527568 0.3171523987434088 5.464704354730218 4.259483301090722 1.5882390061019254 0.3339692919660049 0.0019029662100738 0.0172741819727463 0.0047611483831582 0.0017642589207656 0.001208142066949 +Electron transfer activity 19 62 3.235624384762142 0.0012137698947165 14.919902912621358 52.12621359223301 0.5312195787834075 0.4459804256520286 6.65997259318913 4.498499451328372 1.405540355221493 0.3721784721862224 4.558994839338547e-07 0.0121710399778658 4.91075850128955e-06 2.85318783748576e-05 5.170097538878576e-08 +Protein transporter activity 11 16 3.1920832270672728 0.0014125062623155 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 5.8627690376370164e-08 0.0063255491406275 8.694316847855437e-05 3.619465213529642e-09 7.592473326462904e-09 +Tetrapyrrole binding 11 17 3.1673490755826954 0.0015383553764376 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 2.396629964869704e-05 0.0001247827123008 7.473226732028944e-07 5.100580211902312e-06 7.958293256446512e-06 +Snap receptor activity 12 18 3.055671036512691 0.0022455748450034 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 1.417785173116728e-05 0.151306852499084 0.0041517217414646 0.0012549484261259 2.5872288090814158e-09 +Steroid binding 12 24 3.0388130819837604 0.0023751216930187 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 0.0003032307813171 0.0230489069918226 0.0012207780133745 0.006410021202963 9.85983881561296e-05 +Macromolecule transmembrane transporter activity 7 13 2.9473374510983685 0.0032052321584621 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 1.3019059260235518e-06 0.0040679264544396 3.4550328168080166e-05 1.0378820679868198e-08 1.4497628230363953e-07 +Metal ion transmembrane transporter activity 18 29 2.945574860427644 0.0032235513216474 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.0499636974637507 0.4463627535095094 0.6943670866160305 0.9507072453443336 0.0724526193914442 +Glycolipid binding 9 12 2.9162636195913167 0.0035425104302155 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 1.3105105912470222e-08 1.0 0.1515272625734178 1.8818469985730976e-06 2.392522175580337e-08 +Secondary active transmembrane transporter activity 16 22 2.914534033990684 0.0035621996554577 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.1035911104755814 1.0 1.0 0.6332347998981533 0.1348927714123106 +Palmitoyltransferase activity 2 5 2.891141230628329 0.0038384558048845 1.8786407766990292 5.084951456310679 0.875863834441912 0.3421870647647222 1.2306088543936362 0.6827036113457149 1.018188317250868 0.2997914787323893 0.0522141841666639 1.0 1.0 1.0 0.0618109910728358 +Ceramide binding 5 7 2.888999500936181 0.0038646968749169 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 1.0955822091174204e-05 0.0017062060788896 0.0002296483500821 8.796898694645245e-06 1.6279070379868977e-05 +Protein transmembrane transporter activity 7 12 2.8778091043623464 0.0040044738145523 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 2.834764473614579e-07 0.0029386578360865 1.7352123755419733e-05 2.1333920310054318e-09 2.392522175580337e-08 +Organic acid transmembrane transporter activity 18 24 2.855758603305364 0.0042934142763717 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.1942512681918626 1.0 0.4825947600252522 0.0824194625829831 0.2339293848293204 +Nucleobase containing compound transmembrane transporter activity 10 16 2.846966852742513 0.0044137957963352 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 7.983086697660806e-08 1.0 1.0 0.0001015515149626 1.6112122756911064e-07 +Atp transmembrane transporter activity 4 5 2.841862525264459 0.0044850827168383 3.058252427184466 5.456310679611651 0.5680189081478334 0.3318090311699867 1.598392655736251 0.6936144116307477 1.3025695117924114 0.3140848719976767 9.347050257885534e-06 1.0 1.0 0.0148625463558957 1.3106068439724131e-05 +Oxidoreductase activity acting on a heme group of donors 5 8 2.813157885225139 0.0049057557337237 3.111650485436894 6.483009708737864 0.8850005512180296 0.2757097651603665 1.538237610319269 1.0226572421183926 1.2777814224392188 0.2966482201944345 2.95637055746573e-05 0.0697581245313758 0.0003602808960722 0.0051503840765812 4.367834065541858e-05 +Monooxygenase activity 5 8 2.767377271654283 0.0056509317821278 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.001099560878144 0.0002813337316999 0.0001188562693173 0.0004179970223822 0.0015706126808535 +Wide pore channel activity 4 5 2.689879490192341 0.0071477825820791 2.157766990291262 4.266990291262136 1.156945559067054 0.1661436788367006 1.073449599559222 0.4792567768515825 1.4176309163665306 0.2377490100494037 0.0043638244151776 0.0006219606051344 4.656667989155393e-05 0.0007187465088185 0.0003286021100258 +Membrane insertase activity 7 10 2.617846455019416 0.0088486611463189 2.737864077669903 7.388349514563107 0.8099367695235317 0.306513025583228 1.5809003521008822 1.7333564146948666 1.2685525479217892 0.3048480656363501 9.75287962452586e-07 0.0652597674910206 0.0077184558590264 1.3414362359281e-05 1.5533184688236115e-06 +Sphingolipid binding 6 9 2.6171068745544948 0.0088678571059592 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 7.716967519913913e-06 0.0032958763634803 0.0006327439593496 2.765770662469611e-06 1.2147954097366526e-05 +Voltage gated anion channel activity 4 6 2.614439688261069 0.0089373938164942 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0007024718324135 0.0009934566258862 9.839858993160587e-05 0.001485709034831 0.0009118158302113 +Organophosphate ester transmembrane transporter activity 9 14 2.5959703730216472 0.0094324198082387 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 1.3117156440794916e-08 1.0 1.0 0.0001505310959671 2.5373003202808986e-08 +Nucleotide transmembrane transporter activity 9 14 2.5959703730216472 0.0094324198082387 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 7.454637590337829e-09 1.0 1.0 0.0001186481206876 1.4463829640800043e-08 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 11 31 2.577561686070516 0.009950012027013 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0247183903688906 0.0099984448704361 0.0122106671185157 0.0252029938936908 0.0362411651250499 +Alcohol binding 11 18 2.5691252702347085 0.0101955593830562 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0246216780339059 0.0239365913088697 0.0832345551471358 0.1203869764331773 0.0099411678564375 +Calcium ion binding 25 84 2.5437576003462508 0.0109667159762532 21.00485436893204 81.67961165048544 0.6464856503310022 0.4940276647939897 7.408010340962093 8.52860815905726 1.2261945166831902 0.3858741960292539 0.0074750797798348 0.147549224695827 0.5001507841243509 0.3570210716034063 0.0042414047768271 +Carbohydrate derivative transmembrane transporter activity 7 11 2.533201530638478 0.0113025949747871 4.672330097087379 10.12135922330097 1.0096229459917263 0.2944050311743799 2.686158589641687 1.471354338494036 1.2935479322863277 0.3146313980204608 1.268993662287336e-05 1.0 1.0 0.0033024410276518 2.0974178082134003e-05 +Atpase coupled transmembrane transporter activity 19 25 2.45474019764484 0.0140986440428678 8.072815533980583 22.696601941747577 0.8561067713091313 0.3392846662603397 4.166386392056555 3.892074110340729 1.3163009809214623 0.3229730128136945 0.0043664376704316 1.0 1.0 0.1655021226103433 0.0017715044959542 +Transition metal ion transmembrane transporter activity 6 8 2.45470593989993 0.0140999875569669 2.2597087378640777 4.444174757281553 1.267846808399692 0.205487024774009 1.5353529408674886 1.9618423203326616 1.2931295194130703 0.2516620757205828 0.0215072775985476 0.1093006244161378 0.2070995190727305 0.4452488918515388 0.0269295467729808 +Protein carrier chaperone 8 13 2.453754812992885 0.0141373338241823 3.3980582524271843 10.118932038834952 0.8288787693114796 0.3398938251553178 1.8569721980092944 2.0920401213092656 1.1849901066971258 0.3127406939001886 4.901263183223029e-07 0.083126337411673 0.0126574737404708 5.302129833761715e-05 8.294870660489475e-07 +Lipid binding 49 156 2.452508384130657 0.0141864073393622 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.034092004165829 0.6422059305974207 0.140477041599255 0.0455104591271121 0.0186001904714013 +Molecular carrier activity 13 33 2.3940924271392494 0.0166615495633772 8.985436893203884 32.922330097087375 0.4263347027610819 0.5995318029338973 4.267144921372851 3.1428430650945036 0.9199841946557948 0.3455794463799358 4.085216383289199e-05 0.2406936845278361 0.1039407380726692 0.0120464435451714 7.642967523267423e-05 +Clathrin heavy chain binding 1 6 2.392039251461438 0.0167550504021054 0.9563106796116504 4.172330097087379 0.3682910274765735 0.3434838107739949 1.107360186700709 1.195424695125345 1.3132806864166615 0.2873136636013117 0.0478482703534769 1.0 1.0 0.0148625463558957 0.0542215392640632 +Cation channel activity 6 21 2.3845396086013544 0.0171005070469258 6.628640776699029 20.20145631067961 0.2168681550185727 0.4203796109119975 3.66569707500714 2.3934980322982335 1.245793992642405 0.316602380113191 0.0496917399756219 0.3007677906227077 0.1588529428511447 0.1044322137967542 0.0670258998725707 +Proton channel activity 4 11 2.374538719292143 0.0175708932467537 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 0.0007350148232219 0.0786913117950012 0.0113213926532688 0.00062382482254 0.0010053263520343 +Proton transporting atp synthase activity rotational mechanism 4 11 2.374538719292143 0.0175708932467537 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 0.000538728747922 0.0742352733278267 0.0100519320580488 0.0004862334359502 0.0007388687073799 +Antiporter activity 7 9 2.364746574583673 0.0180424124041036 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 0.007660250712326 1.0 1.0 0.2436114581565515 0.0105883475769395 +Phosphatidylcholine binding 6 8 2.3612167230560632 0.0182150821832831 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 0.033335161975655 0.0026008925831016 0.0100519320580488 0.0561137872346343 0.0397387250697101 +Lysophospholipid acyltransferase activity 6 8 2.3278939591987164 0.0199177351009098 2.4733009708737863 5.805825242718447 0.4588868874829844 0.3808793592027135 1.45207109427004 1.4282738065746603 1.1906123473894044 0.3028968768080747 0.0093740755757518 1.0 1.0 1.0 0.0118865434534573 +Cholesterol binding 9 15 2.326318289828651 0.0200015770195274 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0019656682498461 0.0090330503435184 0.0334071197556988 0.0352396407582777 0.0004675519327548 +Nadh dehydrogenase activity 12 28 2.3130234954960147 0.020721347381416 6.62621359223301 21.9004854368932 0.6460127731992702 0.4045936795236815 3.355345283841267 2.6889381015310834 1.101850132292176 0.306596625090648 0.0005976927895964 0.187449079081247 0.0080456420559546 0.0036383017284534 0.0001790277584403 +Mannosyltransferase activity 3 5 2.30150898497908 0.0213628781091765 2.0509708737864076 5.347087378640777 0.3259733201852472 0.4146291728353291 1.31637337531163 1.1377956298376235 1.1111107346144888 0.2988315692108667 0.195115846167058 1.0 1.0 0.357118555081159 0.2166689846253057 +Nadp retinol dehydrogenase activity 3 6 2.271368296864365 0.0231246919352499 2.279126213592233 5.186893203883495 -0.1272712256841265 0.5017958661005895 1.2354988826075473 0.8903599458953574 0.9807698460452872 0.3018311532776017 0.0010645583219727 1.0 1.0 0.2365379696877526 0.0013781701696679 +Peptide antigen binding 5 8 2.251248028695012 0.0243698324670906 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.0038108776232482 1.0 1.0 1.0 0.0005289198821125 +Mhc protein binding 5 11 2.24600348851755 0.0247037844581163 3.094660194174758 8.968446601941748 0.6294582460885748 0.3884738618046354 1.6140375204875843 0.8821171105149307 1.0893111588562217 0.3109068508502701 0.0002662511149375 1.0 1.0 0.0439142352380576 0.0003671727016274 +Lipid transporter activity 14 23 2.2159873241648125 0.0266923702785688 6.546116504854369 19.805825242718445 0.7389006587243017 0.301332987440896 3.074370954053146 3.741159812966952 1.4134673193588587 0.2984913911167897 0.4638100202363435 1.0 0.5259644699110895 0.5603186564401545 0.3186183875619722 +Amino acid transmembrane transporter activity 10 12 2.207672624363887 0.0272671024992949 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 0.5468983433204527 1.0 0.3209553841799009 0.6257540014635683 0.5850817530243546 +L amino acid transmembrane transporter activity 8 9 2.201982874856825 0.0276665181699915 3.628640776699029 8.201456310679612 0.919975936290114 0.2876791162304417 2.2759730869054327 1.0290432051153906 1.15482978403653 0.2925518180165951 0.7398872858631791 1.0 1.0 1.0 0.7643162941078263 +Solute anion antiporter activity 3 5 2.196295839810229 0.028070775313937 2.3737864077669903 5.444174757281553 0.825822657258252 0.3439291028288794 1.663745987721657 0.8585888447978746 1.0247623924866192 0.2999489358207081 0.0116152577017657 1.0 1.0 0.2365379696877526 0.0140126286640228 +Iron ion binding 8 25 2.1937460880198443 0.0282536685296663 6.524271844660194 22.196601941747577 0.9076096695164306 0.382669917893863 2.4429198675966717 3.289094676807881 0.9378690899634522 0.3126784916965753 0.0570686772983171 0.2552681350600493 0.1163398228410075 0.0600215848699845 0.0744808849197366 +Sterol binding 9 18 2.1882374361867805 0.0286523114969969 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.005126357764941 0.0128452267182733 0.0466281418945222 0.0558093330619567 0.0014896299843671 +Hexosyltransferase activity 15 39 2.1859486414167417 0.028819362997261 9.633495145631068 33.87864077669903 0.7349501031127185 0.3949358882560483 4.261380470236419 4.330948695045228 1.2646745007039175 0.3422146027467064 0.073593350394818 1.0 0.6695171460893661 0.1429687098473413 0.1020793726789788 +Neutral amino acid transmembrane transporter activity 4 5 2.18507745548045 0.0288831679331815 2.2014563106796117 4.604368932038835 0.4961979429298074 0.422433136266165 1.3637817977156623 0.906438855008838 1.0374761107148884 0.3077443591708454 1.0 1.0 1.0 1.0 1.0 +Oxidoreductase activity acting on nad p h 12 37 2.1819506673603466 0.0291131738309242 8.531553398058252 29.633495145631063 0.3474448637287304 0.4517187142808695 4.100257452793358 3.3245401780708717 1.1430154641923982 0.3174571972624041 4.010847784918796e-05 0.2766173679843171 0.0264876267470493 0.02289977346361 1.620623892082362e-05 +C4 dicarboxylate transmembrane transporter activity 5 6 2.1458608871621467 0.031884079141863 2.5800970873786406 5.762135922330097 0.7175594553016044 0.3314419534241876 1.791536735339018 0.4257754786552994 1.1176795047305017 0.2969876515759702 0.3997040719021639 1.0 1.0 0.2365379696877526 0.4217257773445009 +Molecular transducer activity 18 45 2.1430944906145237 0.0321055117703303 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.9042927039346028 1.0 0.9198528304142816 0.9522253594512896 0.8856536931091339 +Anion channel activity 6 11 2.1143258631465978 0.0344874448565326 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 0.0013466796425634 0.0078974776787256 0.0023694947377154 0.0004989114687539 0.001918269568256 +Purine nucleotide transmembrane transporter activity 6 11 2.11123844978131 0.0347518214887034 4.334951456310679 9.441747572815531 0.9917737457277228 0.2833655940290197 2.4104227054611673 1.6217588601139772 1.262135146193827 0.3001583617421954 3.002919287037127e-06 1.0 1.0 0.0062267265321947 4.754797566677231e-06 +P type transmembrane transporter activity 3 6 2.109079145538178 0.0349377506190751 2.842233009708738 5.473300970873787 0.6050493013674468 0.3730987003611934 1.6045635356324264 1.3712604140019378 1.17652933932801 0.3174788438558891 0.0149736639257102 1.0 1.0 1.0 0.018020673376298 +Mhc class i protein binding 4 9 2.0909796254339383 0.0365298904348974 2.7135922330097086 7.936893203883495 0.4997309801019018 0.4236810840517632 1.5643199175999352 0.8594975153459443 1.0647070901951394 0.3142832966160581 0.0010645583219727 1.0 1.0 0.2365379696877526 0.0013781701696679 +Palmitoyl protein hydrolase activity 2 7 2.0848016024906637 0.0370873132073339 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0149736639257102 1.0 0.1094892401774078 0.0328731354880699 0.018020673376298 +Fad binding 6 10 2.083434391551789 0.0372116461672629 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.111398140820949 1.0 1.0 0.4718643991127431 0.1298078118605267 +Acylglycerol o acyltransferase activity 6 9 2.071133653735581 0.0383463076319934 2.6601941747572817 6.820388349514563 0.8174935736497821 0.2734948556707107 1.708365471336677 1.514259678343348 1.2372108727630755 0.2654117957889352 0.0134770599498747 1.0 1.0 1.0 0.017002584405276 +Tap binding 4 6 2.0506986925136323 0.0402962983860955 1.8592233009708736 3.895631067961165 0.8127354819395453 0.3477955376218754 1.070154411615344 1.0456940556701602 1.051123567423606 0.2887299843781864 0.0369771588694818 1.0 1.0 1.0 0.0034377129995212 +Solute cation symporter activity 8 9 2.0500290951261757 0.0403615916762063 2.854368932038835 7.206310679611651 0.8639239563858236 0.3319920905256767 1.9640347167867271 2.0653542869596597 1.117186698589392 0.3146562336443082 0.7840465026909587 1.0 1.0 1.0 0.8069764513835189 +Long chain fatty acid coa ligase activity 2 6 2.0480616576440425 0.0405539582692828 2.4563106796116503 5.089805825242719 -0.1622804075961988 0.5218690302058434 1.6207195994320032 0.875332370252962 0.904312921049039 0.2936915990388986 0.3711832246405026 1.0 1.0 0.2175647207167039 0.3921885014959403 +Arachidonate coa ligase activity 2 6 2.0480616576440425 0.0405539582692828 2.4199029126213594 4.936893203883495 -0.1487046814490792 0.5291043872447513 1.5566618473769105 0.7888162805856125 0.8945185428241254 0.2923194839224564 0.3413103865779423 1.0 1.0 0.1981219124770219 0.361145714490569 +Phospholipid transporter activity 2 7 2.042566446971478 0.0410953754288228 2.1771844660194173 6.699029126213592 0.5736831867868913 0.3651436001806147 1.523334307555052 1.8451455672114891 1.0803825413008894 0.2760174807519195 0.4600843832656368 1.0 0.2802926639431586 0.5661975770404395 0.4967295098899271 +Glycosyltransferase activity 14 54 2.0383182905593085 0.0415181118547951 10.808252427184469 46.75 0.6230735361107147 0.5000303532444054 4.489970468729936 5.6981622825309435 0.9932734853426128 0.358363386747457 0.1069519644292459 1.0 0.787267589662925 0.188628685616608 0.1502953664119072 +Oligosaccharyl transferase activity 4 5 2.032249144101548 0.0421284400410926 2.0800970873786406 4.449029126213592 0.3253650630697351 0.4526354423109099 1.2831590228622023 0.6896066341264963 1.063820674508784 0.3223663395492768 0.0272184914162367 1.0 1.0 0.1368589802283267 0.0309764532364539 +Copper ion binding 5 10 2.031140613476473 0.0422407325803166 2.4805825242718447 9.395631067961164 0.298010576811855 0.4301582785794527 1.6552686258647775 1.5426872090784312 1.0475904656710089 0.2911939339780537 0.017555941435959 1.0 0.2802926639431586 0.5661975770404395 0.0053527619374205 +Oxidoreductase activity 58 247 1.9917925790861903 0.0463938208150889 52.54126213592233 227.42961165048544 0.490492706528076 0.5955656171597654 20.033606385640603 16.688970744458114 1.2909283370539455 0.4039853598071011 2.8337233169931184e-10 7.109535134557627e-05 2.4510887740493315e-06 1.1882923493329328e-05 1.7247063236472015e-11 +Organic cation transmembrane transporter activity 2 5 1.9870675621121836 0.0469149103235408 1.9271844660194175 5.04126213592233 1.6158747778246996 0.14183106997637 1.275055237696066 0.9168044752551467 0.8418646651592007 0.1871331589544055 0.0231652698963574 1.0 1.0 0.0439142352380576 0.0277461310389573 +Sodium ion transmembrane transporter activity 6 7 1.9868766462655505 0.0469360682015287 3.033980582524272 6.733009708737864 0.6330876716410718 0.3951789521880264 1.773267150762252 1.4834287460359985 1.0827590126064015 0.3202441368223486 0.8440880013485742 1.0 1.0 1.0 0.8639284467153323 +Sulfur compound transmembrane transporter activity 5 8 1.9860968196611253 0.0470225743545704 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.0090121117169049 1.0 1.0 0.0322769586697076 0.0119362160344991 +Symporter activity 10 11 1.9760634935423345 0.0481475864480531 3.638349514563106 9.1747572815534 0.9770544165414302 0.3122690599192905 2.3735568316725377 2.065327188945721 1.1044541290009051 0.3081067804681572 0.8705838127794983 1.0 1.0 1.0 0.8885829250272372 +Gated channel activity 6 13 1.964894873617572 0.0494264061917242 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 0.0533997763908819 0.0335548880884004 0.0198486300115185 0.0571243888921134 0.0698685551762488 +Myosin v binding 2 6 1.9643083721010717 0.049494341382497 2.0072815533980584 4.330097087378641 0.0207399319066686 0.576708316376031 1.3995302222738102 1.1481377874295209 0.850471624661882 0.3035377546950971 0.1302665862694917 1.0 1.0 0.290751966651369 0.1457988469723397 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..69fb83e8f93f304f64a4eed6aedbd594e8daaefd --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 1405, + "title": "Average number of proteins per term", + "value": 17.177224199288258 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1df69ae404015c615fffe2c0e3bbec8efeb986d4 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..144bbe7c82ef8d7150b7bb94687130abfa65c4bf --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,357 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.6276666769657342 5.717143688915986 1.0832951076883322e-08 1.5220180518743637e-05 7.610148132213034e-06 196 P04062,P28288,Q4KMQ2,Q8N4V1,Q99595,Q9NWR8,Q9NS69,Q9NZD2,Q9UDW1,Q9Y584,Q9Y6M9,P13073,P53007,O43676,O60830,Q9UJS0,P00846,P45880,Q15043,P21796,P36383,Q9Y277,O95169,P20674,O15173,P17900,Q96H78,Q02978,O75964,O95167,P00403,Q9Y619,Q9H4L5,P24539,Q8N1S5,Q9BSK2,O75746,Q9BQT8,P08195,O14925,O96000,Q9Y5J9,O43808,Q03518,L0R6Q1,P49755,O75947,Q8TB61,O43674,Q96AA3,P12235,P56556,Q9C0H2,Q9BZF3,Q9Y6M7,Q70HW3,Q9Y487,Q96S66,O75027,P03886,Q9UGP8,Q9UBX3,Q96NB2,Q15388,O14975,Q9UI09,Q9H2D1,P06576,Q07820,P36543,Q8NEW0,P36542,Q9H0U3,P56385,P16615,O14548,O43681,Q96ER9,O95202,Q9P0J0,P12236,Q7KZN9,Q96GC9,P30536,P35670,Q03519,Q9HD20,Q6NUK1,Q9UM00,Q6P4A7,O00400,O95168,Q9HC21,P51790,Q14728,O95139,P05023,Q13423,P30825,Q6NXT4,P05141,Q9NQ11,Q8NE01,P03915,P08574,Q93050,O96008,O15118,P98194,Q8NBU5 110 +Ion transmembrane transporter activity 0.6218557895072246 5.020113017175513 5.164108719862056e-07 0.0007252943093173 0.0002418524250473 115 O75746,Q4KMQ2,Q8N4V1,Q9BQT8,P08195,Q9HC21,Q15758,P51790,Q14728,P56385,P11166,Q9NWR8,P16615,Q9UDW1,O14548,O43681,P13073,P53007,Q96ER9,O43808,P47985,O95202,Q9UJS0,P00846,Q6PML9,P12236,P45880,Q7KZN9,Q15043,O75947,P21796,P36383,Q8TB61,P05023,Q9Y277,P12235,P30825,Q13423,Q9C0H2,P20674,P35670,Q6NXT4,P05141,Q9Y6M7,Q70HW3,Q9Y487,Q96S66,Q9NQ11,Q02978,Q9HD20,P08574,O75964,Q9UBX3,P00403,Q6NUK1,Q9UM00,Q9Y619,Q96NB2,Q6P4A7,Q8NEW0,P24539,Q93050,Q8N1S5,Q9H2D1,P06576,P36543,P98194,O00400,P36542,Q9Y5K8,Q9H0U3 71 +Cation transmembrane transporter activity 0.6420899144365235 4.655518515031759 3.2316636215945493e-06 0.004530202262364 0.0011351218470854 81 Q4KMQ2,Q8N4V1,P08195,Q9HC21,Q15758,P51790,P56385,P16615,Q9UDW1,O14548,P13073,Q96ER9,O43808,P47985,O95202,P00846,Q6PML9,Q7KZN9,Q15043,O75947,P05023,P12235,Q13423,P30825,P20674,P35670,Q6NXT4,P05141,Q9Y6M7,Q70HW3,Q9Y487,Q9NQ11,Q9HD20,P08574,O75964,P00403,Q9UM00,Q93050,Q9Y619,Q96NB2,Q8NEW0,P24539,Q8N1S5,P06576,P36543,P98194,O00400,P36542,Q9Y5K8,Q9H0U3 50 +Inorganic molecular entity transmembrane transporter activity 0.6065015408369301 4.374215954194338 1.218696907723249e-05 0.0169770339580141 0.0034245383107026 87 Q4KMQ2,Q8N4V1,P08195,P51790,P56385,Q9NWR8,P16615,Q9UDW1,O14548,O43681,P13073,Q96ER9,O95202,P00846,P45880,Q7KZN9,Q15043,O75947,P21796,P36383,P05023,Q9Y277,P12235,Q13423,Q9C0H2,P20674,P35670,Q6NXT4,P05141,Q9Y6M7,Q9Y487,Q96S66,Q9NQ11,Q02978,Q9HD20,P08574,O75964,Q9UBX3,P00403,Q9UM00,Q93050,P24539,Q8N1S5,P06576,P36543,P98194,O00400,P36542,Q9H0U3 49 +Active transmembrane transporter activity 0.5978703516937329 4.266885855623991 1.982205127704084e-05 0.0274660149854782 0.0046416636740406 85 P28288,O95168,P08195,Q15758,P51790,O96000,P16615,Q9UDW1,O14548,Q9Y6M9,P13073,P53007,O43676,P47985,O95202,Q9P0J0,O95139,Q03518,P12236,Q7KZN9,P20020,Q15043,O43674,P05023,P56556,P12235,O95169,O75306,P20674,P35670,Q03519,P05141,Q9Y6M7,Q9NQ11,O75027,P03886,Q02978,Q9HD20,P55011,P51970,P03915,P08574,O95167,P00403,Q9UBX3,Q15388,Q9UI09,Q9H936,P06576,P36543,P98194,O00400,Q9BXP2,Q9Y5K8 54 +Primary active transmembrane transporter activity 0.5905877496715826 4.055434329398959 5.004123071628008e-05 0.0678948869026679 0.0064039241882083 63 O95168,O96000,P16615,O14548,Q9UDW1,Q9Y6M9,P13073,O43676,Q9P0J0,O95139,Q7KZN9,P05023,P35670,P20674,Q03519,Q9NQ11,O75027,P03886,Q9HD20,P03915,P08574,O95167,P00403,Q15388,P06576,P98194 26 +Proton transmembrane transporter activity 0.6889089634085412 3.8793181547272817 0.0001047496749806 0.1368622664343039 0.0064039241882083 39 P13073,P20674,O14548,P24539,O95202,P05141,P51790,P00846,P56385,Q7KZN9,P06576,P00403,O00400,Q9UDW1,P08574,O75964,P12235,Q13423 18 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9833479404031552 3.75262124839233 0.0001749951460705 0.2179915208621108 0.0069998420362697 2 P09601 1 +Active ion transmembrane transporter activity 0.6214244916190858 3.69068026808497 0.0002236551212155 0.2696786167772028 0.0071972194875597 47 P08195,P51790,P16615,O14548,Q9UDW1,P13073,P53007,P47985,O95202,P12236,P20020,Q7KZN9,Q15043,P05023,P12235,P35670,P20674,P05141,Q9Y6M7,Q9NQ11,Q9HD20,Q02978,P55011,P08574,P00403,O00400,P36543,P06576,P98194,Q9H936,Q9BXP2,Q9Y5K8 32 +Sphingosine n acyltransferase activity 0.9614373356704672 3.654153702523893 0.0002580316659466 0.3041222435733211 0.0077134998011703 2 Q96G23 1 +Anion transmembrane transporter activity 0.6027008215713578 3.6295742413416527 0.0002838890752123 0.3289561393009992 0.0078208656994781 49 O75746,Q99808,Q96QD8,Q4KMQ2,P08195,Q9HC21,Q9BQT8,Q15758,Q14728,P51790,P11166,Q9H9B4,O43681,P53007,O43808,Q9UJS0,P12236,P45880,Q15043,P21796,Q8TB61,P12235,Q9Y277,P30825,Q9C0H2,P05141,Q9Y6M7,Q96S66,Q02978,P55011,Q6NUK1,Q9UBX3,Q9Y619,Q96NB2,O00400,Q9H2D1,Q9H936,Q9BXP2 38 +Aminoacyltransferase activity 0.9392345895413404 3.553115193016386 0.0003806977202371 0.4143202477378462 0.0081488329158552 2 Q9NXS2 1 +Heme transmembrane transporter activity 0.9380660239555976 3.5477615789323407 0.0003885197437487 0.4207240446475864 0.0081488329158552 2 O15173 1 +Phospholipase d activity 0.9325153374233172 3.52228238908226 0.0004278481352975 0.4518768342328444 0.0081488329158552 2 P09601 1 +Organic anion transmembrane transporter activity 0.6608424885504482 3.5006371460667514 0.0004641473444766 0.4791423021948237 0.008469182064801 34 O75746,Q99808,Q96QD8,P08195,Q9HC21,Q9BQT8,Q15758,Q14728,P11166,Q9H9B4,P53007,O43808,Q9UJS0,P12236,Q8TB61,P12235,P30825,P05141,Q9Y6M7,Q02978,Q6NUK1,Q9UBX3,Q9Y619,Q96NB2,O00400,Q9H2D1,Q9H936 27 +Carnitine o acyltransferase activity 0.9173239848086476 3.4521273432357096 0.0005561851669568 0.5423531915241451 0.0090734127020557 2 P50416 1 +O palmitoyltransferase activity 0.9173239848086476 3.4521273432357096 0.0005561851669568 0.5423531915241451 0.0090734127020557 2 P50416 1 +3 hydroxyacyl coa dehydratase activity 0.9000876424189348 3.3717660099674647 0.0007468787350719 0.6499770979000385 0.0096200212097228 2 Q6Y1H2 1 +Oxidoreduction driven active transmembrane transporter activity 0.6264583604389237 3.3694553516422157 0.0007531689203341 0.653059171222228 0.0096200212097228 38 P13073,O43676,O95168,P20674,O14548,Q9P0J0,O95139,P03915,O96000,Q7KZN9,P03886,Q9UDW1,Q9Y6M9,O95167,P00403 15 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.926943308007012 3.3515629488065453 0.0008035676790221 0.6767943435818491 0.0099036192019831 3 Q14534,Q16850 2 +Passive transmembrane transporter activity 0.631687588548444 3.344323647558119 0.0008248345124604 0.6863164802556313 0.0099904525000592 36 Q9C0H2,Q4KMQ2,Q96ER9,P24539,O96008,P51790,P00846,P56385,P45880,Q96S66,Q9NWR8,P06576,P21796,O75964,Q9Y277,Q9UM00 16 +Solute proton antiporter activity 0.8851884312007031 3.3016341845355113 0.0009612334497011 0.7410661102580348 0.0108385494723296 2 O95202 1 +Mitochondrion targeting sequence binding 0.9144741003219046 3.294480593182642 0.0009860375316508 0.7499429534561826 0.010908525448578 3 Q9Y584 1 +Lysophosphatidic acid binding 0.9079485680888416 3.2644421146242784 0.0010967987193128 0.786014688397746 0.0115864827115385 3 O14773,P50897 2 +Electron transfer activity 0.5071939561843231 3.235624384762142 0.0012137698947165 0.8184787386191252 0.0125033279153309 62 P21912,O95168,O96000,O14548,Q9UDW1,Q9Y6M9,P13073,P16435,O43676,Q9P0J0,O95139,P14406,Q7KZN9,P20674,P03886,P03915,O95167,P00403,O14957 19 +Azole transmembrane transporter activity 0.8694127957931643 3.22668843529957 0.0012523174186753 0.8280598149353013 0.0125033279153309 2 Q9HC21 1 +Oxidative phosphorylation uncoupler activity 0.8667835232252472 3.2141276106049927 0.0013084150972577 0.8411074206472857 0.0125389503822614 2 P12235 1 +Nucleobase transmembrane transporter activity 0.8667835232252472 3.2141276106049927 0.0013084150972577 0.8411074206472857 0.0125389503822614 2 P12235 1 +Glycosphingolipid binding 0.8965517241379355 3.2117036794079494 0.0013195039841003 0.843566971097613 0.0125389503822614 3 Q9NZJ7,P07602 2 +Ganglioside binding 0.8965517241379355 3.2117036794079494 0.0013195039841003 0.843566971097613 0.0125389503822614 3 Q9NZJ7,P07602 2 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.8638621092608867 3.200147507724868 0.0013735726989527 0.8550253334252138 0.0125389503822614 2 Q53GQ0 1 +Protein transporter activity 0.817147525285019 3.1920832270672728 0.0014125062623155 0.8627531609559032 0.0128036857971187 16 O60830,Q15388,O96008,O14925,Q99595,P49755,Q9Y5J9,Q9NS69,Q07820,Q9HD20,Q9Y584 11 +Tetrapyrrole binding 0.7898397558722442 3.1673490755826954 0.0015383553764376 0.8850264875069462 0.0132600570791098 17 Q9NUN5,P53701,Q9H7Z7,Q16850,P09601,O15173,O43169,Q7KZN9,O00264,P30519,Q6UW02 11 +Ion gated channel activity 0.8495471808355318 3.131282321795758 0.001740447575556 0.9134868885702144 0.0140116091582791 2 Q9C0H2 1 +Phospholipid scramblase activity 0.8495471808355287 3.131282321795758 0.001740447575556 0.9134868885702144 0.0140116091582791 2 Q96GC9 1 +Intracellular calcium activated chloride channel activity 0.8495471808355318 3.131282321795758 0.001740447575556 0.9134868885702144 0.0140116091582791 2 Q9C0H2 1 +Voltage gated chloride channel activity 0.8495471808355264 3.131282321795758 0.001740447575556 0.9134868885702144 0.0140116091582791 2 P51790 1 +Magnesium ion transmembrane transporter activity 0.8769258891855183 3.1200494079438466 0.001808207076698 0.9213565252339796 0.0143532821624901 3 Q8N4V1 1 +Iron ion transmembrane transporter activity 0.8355243938066149 3.0632305192628 0.0021896131706471 0.9540306081927604 0.0159399300764727 2 Q8N4V1 1 +Snap receptor activity 0.7552155346165624 3.055671036512691 0.0022455748450034 0.9575139885829078 0.016167986056666 18 P56962,O95721,O15400,O43752,O95249,O60499,O15155,O75396,Q13190,Q9P2W9,Q12981,Q9UEU0 12 +Steroid binding 0.6585032756765694 3.0388130819837604 0.0023751216930187 0.9645989999776514 0.0166298376835001 24 P04062,O75477,P60033,O15118,O15173,O94905,P45880,O00264,Q14108,P21796,P05023,P30536 12 +Gpi anchor binding 0.8553477498538831 3.018029080528848 0.0025442448858921 0.9721025279827186 0.0172141031618988 3 Q9H490,O43292 2 +Lipid kinase activity 0.82617586912066 3.01753187439707 0.0025484223898042 0.9722662051723704 0.0172141031618988 2 Q53H12 1 +Succinate transmembrane transporter activity 0.8250073035349196 3.011800744832984 0.0025970300511515 0.9741015847162312 0.0172930200088525 2 Q9UBX3 1 +Sulfate transmembrane transporter activity 0.8250073035349196 3.011800744832984 0.0025970300511515 0.9741015847162312 0.0172930200088525 2 Q9UBX3 1 +Sulfatide binding 0.8827522946902076 3.0087150094366644 0.0026235508924583 0.9750512809496096 0.017387212282566 4 O14773,P50897 2 +L ornithine transmembrane transporter activity 0.822085889570555 2.9974545416519622 0.0027224445761322 0.978295828919212 0.0179579090585248 2 P30825 1 +Porin activity 0.874341440214516 2.9696915069270933 0.0029809894130057 0.9849224015561086 0.0185322571914736 4 P45880,P21796 2 +Macromolecule transmembrane transporter activity 0.8343249798473581 2.9473374510983685 0.0032052321584621 0.9890079586817287 0.0189385589848057 13 O60830,Q15388,O14925,P49755,Q99595,Q9NS69,Q9Y584 7 +Fibronectin binding 0.811568799298869 2.945589494717782 0.0032233988308638 0.9892858530573686 0.0189385589848057 2 Q53GQ0 1 +Metal ion transmembrane transporter activity 0.6037526630661672 2.945574860427644 0.0032235513216474 0.9892881557344788 0.0189385589848057 29 Q96ER9,Q8N4V1,P08195,O95202,Q6NXT4,P35670,Q9Y6M7,Q8N1S5,P20020,Q15043,P16615,Q9H0U3,P98194,Q9HD20,P55011,P05023,Q9BXP2,Q9UM00 18 +Branched chain amino acid transmembrane transporter activity 0.8112766579024376 2.944143884646542 0.003238494020282 0.9895114149802524 0.0189385589848057 2 Q96H78 1 +Calcium cation antiporter activity 0.8112766579024326 2.9441438846465005 0.0032384940202825 0.9895114149802589 0.0189385589848057 2 O95202 1 +Cation cation antiporter activity 0.8112766579024326 2.9441438846465005 0.0032384940202825 0.9895114149802589 0.0189385589848057 2 O95202 1 +Aromatic amino acid transmembrane transporter activity 0.8112766579024282 2.944143884646479 0.0032384940202827 0.9895114149802622 0.0189385589848057 2 P30825 1 +Adp transmembrane transporter activity 0.8672902660040993 2.9368270523422204 0.0033158897089222 0.9905954929706108 0.0190935452501466 4 O43808,P12235,P12236 3 +Glycolipid binding 0.8478988221993518 2.9162636195913167 0.0035425104302155 0.9931674954201146 0.0201507172245056 12 Q9NZJ7,Q9UM22,P50897,P07602,Q9H490,O14773,O43292,Q9NZD2,Q9NWW5 9 +Secondary active transmembrane transporter activity 0.6715572415510956 2.914534033990684 0.0035621996554577 0.9933545704860062 0.0201810101448314 22 P53007,O00400,P08195,O95202,P05141,Q15758,P51790,Q9Y6M7,P12236,Q15043,Q9H936,Q9BXP2,Q02978,P55011,Q9UBX3,P12235 16 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.8325540619520725 2.9088038136110166 0.0036281445977881 0.9939446487868008 0.0203901726395694 3 O00767,O75845 2 +Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor 0.8304843086987963 2.898810187099628 0.0037458158627934 0.9948705295161452 0.0207053110548768 3 O43169 1 +Nitrite reductase activity 0.8304843086987963 2.898810187099628 0.0037458158627934 0.9948705295161452 0.0207053110548768 3 O43169 1 +G protein alpha subunit binding 0.8290073248589354 2.8916709265240055 0.0038319908422153 0.9954575518866238 0.0208328500568828 3 P80303 1 +Palmitoyltransferase activity 0.8782014354372489 2.891141230628329 0.0038384558048845 0.9954987827702794 0.0208328500568828 5 P50416,O15269 2 +Ceramide binding 0.8898772558688238 2.888999500936181 0.0038646968749169 0.9956623331967236 0.0208328500568828 7 Q9NZJ7,P07602,P45880,Q9NZD2,P21796 5 +Protein transmembrane transporter activity 0.8401446780697428 2.8778091043623464 0.0040044738145523 0.9964385269121204 0.0211514500355116 12 O60830,Q15388,O14925,P49755,Q99595,Q9NS69,Q9Y584 7 +Sulfotransferase activity 0.8220338983050981 2.8578758822685075 0.0042648717639155 0.9975335098731224 0.0217896175574594 3 Q7LGA3,Q8NCH0 2 +Organic acid transmembrane transporter activity 0.6318518252334433 2.8557586033053637 0.0042934142763717 0.9976308729164012 0.0218198172178384 24 O75746,P53007,P30825,Q96QD8,Q9Y619,Q96NB2,Q9BQT8,P08195,Q15758,Q9UJS0,O14975,Q9H2D1,Q96H78,Q9H936,Q02978,Q9H9B4,Q9UBX3,P33527 18 +Beta 1 3 galactosyltransferase activity 0.7931638913234079 2.853991173208527 0.0043173730865189 0.9977096288366494 0.0218198172178384 2 Q96L58 1 +Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity 0.7931638913234079 2.853991173208527 0.0043173730865189 0.9977096288366494 0.0218198172178384 2 Q96L58 1 +Nucleobase containing compound transmembrane transporter activity 0.7543849309109866 2.846966852742513 0.0044137957963352 0.9980010021877588 0.0221477967637537 16 O43808,Q9HC21,P12236,L0R6Q1,Q9H2D1,Q8TB61,O00400,Q6NUK1,P12235,Q9BSK2 10 +Zinc ion transmembrane transporter activity 0.8188194038573938 2.842248613587948 0.0044796543684575 0.9981784252610348 0.0222669300959642 3 Q15043,Q6NXT4 2 +Atp transmembrane transporter activity 0.8675438596491263 2.841862525264459 0.0044850827168383 0.998192327333097 0.0222669300959642 5 P12235,Q6NUK1,O43808,P12236 4 +Dolichyl phosphate mannose protein mannosyltransferase activity 0.7899503359626077 2.837887501298909 0.0045413185587046 0.9983302554846898 0.0224667344189438 2 Q6ZXV5 1 +Lipase binding 0.7890739117733023 2.833489848667748 0.0046042770332612 0.9984722323456264 0.0226189133976646 2 Q96CS3 1 +Arylesterase activity 0.7879053461875685 2.827622475991435 0.0046895073191759 0.9986454083924516 0.0227984698389003 2 Q15165 1 +Oxidoreductase activity acting on a heme group of donors 0.8646973320332506 2.813157885225139 0.0049057557337237 0.9990017920903904 0.0236858653123088 8 P13073,P20674,Q7KZN9,O14548,P00403 5 +Solute cation antiporter activity 0.8115137346581003 2.806616366181335 0.0050064826241746 0.9991341294562356 0.0240356125758302 3 O95202,P51790 2 +Cytochrome b5 reductase activity acting on nad p h 0.8093034377602766 2.7958041721463385 0.0051770759248201 0.9993195018115462 0.0246534314932721 3 P16435 1 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.8335355156252782 2.7775784854466083 0.0054765611962321 0.999554233645778 0.0258206995996853 4 Q7KZN9,P16435 2 +Monooxygenase activity 0.85499414207467 2.767377271654283 0.0056509317821278 0.999651571313542 0.0260313414881626 8 Q14534,Q16850,P09601,P30519,Q6UW02 5 +Tap1 binding 0.7998246639392259 2.7492677075478196 0.0059728581825089 0.999778929234313 0.0273963612918635 3 P30511,Q03519 2 +2 acylglycerol 3 phosphate o acyltransferase activity 0.8213972522654253 2.7195197488414196 0.0065376790928171 0.9999005242202298 0.0290577484056545 4 Q8NF37,Q96N66,Q92604 3 +Catalytic activity acting on a glycoprotein 0.7933956750438443 2.7175474959860213 0.0065767715252655 0.9999058747073192 0.0290577484056545 3 Q96L58,Q9BYC5 2 +Wide pore channel activity 0.8350877192982641 2.689879490192341 0.0071477825820791 0.9999580359711568 0.0307114205743767 5 P45880,P21796,Q9Y277,O96008 4 +Beta 2 microglobulin binding 0.7820741046393498 2.6613765622257 0.0077821869432845 0.9999829052607956 0.0318015673287029 3 P55899 1 +Mhc class ib protein binding 0.7799956473908585 2.6510210911500907 0.0080248830000935 0.999987877462472 0.0322141731860897 3 Q03519 1 +Glucuronosyltransferase activity 0.7776154295733461 2.639145540566774 0.0083115289992652 0.9999919230691234 0.0331752791021808 3 O43505,Q9P2E5 2 +Volume sensitive anion channel activity 0.7741368595065989 2.6217580122494475 0.0087477519207599 0.9999956470838036 0.034331261029798 3 Q9C0H2 1 +Membrane insertase activity 0.8066760455067679 2.6178464550194156 0.0088486611463189 0.9999962272277017 0.03451340507998 10 Q8N4V1,Q8N8Q8,Q8N766,Q15006,Q9NPA0,Q9Y5J7,Q15070 7 +Sphingolipid binding 0.8151529205442185 2.6171068745544948 0.0088678571059592 0.9999963285057925 0.03451340507998 9 Q9NZJ7,Q99623,P07602,P45880,P21796,Q9NZD2 6 +Voltage gated anion channel activity 0.8389641636953473 2.614439688261069 0.0089373938164942 0.9999966731628404 0.0346124588549377 6 P45880,P51790,Q9Y277,P21796 4 +Intermediate filament binding 0.7726354654612905 2.614241571356149 0.0089425783376102 0.9999966975253216 0.0346124588549377 3 P08670 1 +O acetyltransferase activity 0.7703376903988707 2.602724431176691 0.0092486259227855 0.9999978601660152 0.0356986797294331 3 Q8NF37 1 +Organophosphate ester transmembrane transporter activity 0.7481492803718527 2.5959703730216472 0.0094324198082387 0.9999983511747078 0.0360677808547647 14 O43808,Q9HC21,P12236,Q9H2D1,Q8TB61,O00400,Q6NUK1,P12235,Q9BSK2 9 +Nucleotide transmembrane transporter activity 0.7481492803718527 2.5959703730216472 0.0094324198082387 0.9999983511747078 0.0360677808547647 14 O43808,Q9HC21,P12236,Q9H2D1,Q8TB61,O00400,Q6NUK1,P12235,Q9BSK2 9 +Cation chloride symporter activity 0.7405784399649409 2.5862417946243417 0.0097028837725257 0.9999988765656572 0.0364506729957182 2 P55011 1 +Potassium chloride symporter activity 0.7405784399649409 2.5862417946243417 0.0097028837725257 0.9999988765656572 0.0364506729957182 2 P55011 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5503362365870635 2.577561686070516 0.009950012027013 0.9999992088522816 0.037180231111578 31 O00767,P16435,Q16850,Q14534,P09601,O75845,Q9BU89,P30519,Q6PK18,Q15800,Q6UW02 11 +L glutamine transmembrane transporter activity 0.7376570260005844 2.571097405240933 0.0101376809166131 0.9999993938456052 0.0373923135951238 2 Q15758 1 +Amino acid cation symporter activity 0.7376570260005819 2.571097405240918 0.0101376809166136 0.9999993938456052 0.0373923135951238 2 Q9H936 1 +Alcohol binding 0.6736153348924699 2.5691252702347085 0.0101955593830562 0.999999441653213 0.0374014645775302 18 Q9H4L5,O75477,P60033,Q9BZF3,O15118,O94905,O14735,P45880,Q14108,P21796,P30536 11 +P type calcium transporter activity 0.7618351841028683 2.559961906757886 0.0104683637222784 0.9999996209422112 0.0381037591445627 3 P16615,P98194 2 +Udp xylosyltransferase activity 0.7608718755340742 2.5551025511670615 0.0106156516939726 0.999999692478726 0.0385400274677816 3 Q8NBI6 1 +Pre mrna 3 splice site binding 0.7591913911881598 2.5466183601608803 0.0108772317715537 0.9999997879055234 0.0391021186637958 3 P26368 1 +Calcium ion binding 0.4399123193416498 2.5437576003462508 0.0109667159762532 0.9999998132224792 0.0393067243536626 84 Q96A33,O43852,Q02818,Q14257,P16615,Q9BRK5,Q99584,O43681,O95302,P27824,O95202,Q8WVQ1,P55327,O75071,P80303,Q14118,P41208,P60660,Q8IYU8,Q8NF37,O60476,Q6NUK1,Q9UM22,Q9NWM8,Q9Y680 25 +Aspartic endopeptidase activity intramembrane cleaving 0.7312299152790057 2.5376778733002916 0.0111590644741974 0.9999998578837546 0.0394626220867221 2 Q92542 1 +Carbohydrate derivative transmembrane transporter activity 0.7811223101728918 2.533201530638478 0.0113025949747871 0.999999884103858 0.03950285059596 11 O43808,P12236,L0R6Q1,Q8TB61,O00400,Q6NUK1,P12235 7 +Intramembrane lipid transporter activity 0.7803622368825955 2.5200474041855583 0.0117339030599552 0.9999999372194482 0.0409085205936405 4 Q96GC9,Q96AA3 2 +Oxidoreductase activity acting on other nitrogenous compounds as donors 0.7749712635797505 2.4934684298055836 0.0126501833256267 0.9999999829460468 0.0431395814866639 4 O43169 1 +Galactoside binding 0.7192521180251271 2.475019887896944 0.0133228756663785 0.9999999934542644 0.0444274306815898 2 P16278 1 +Galactosidase activity 0.7192521180251271 2.475019887896944 0.0133228756663785 0.9999999934542644 0.0444274306815898 2 P16278 1 +Procollagen proline 4 dioxygenase activity 0.7419637638807719 2.4591197820744943 0.0139278139754217 0.9999999972347398 0.0454033997995466 3 P13674,P07237 2 +Peptidyl proline 4 dioxygenase activity 0.7419637638807719 2.4591197820744943 0.0139278139754217 0.9999999972347398 0.0454033997995466 3 P13674,P07237 2 +Atpase coupled transmembrane transporter activity 0.5613016256035379 2.4547401976448397 0.0140986440428678 0.999999997832212 0.0457153722747798 25 P28288,P16615,P33527,P08183,Q03518,P20020,Q9NRK6,P05023,P35670,Q03519,Q9NQ11,P21281,O75027,Q9HD20,Q15388,P36543,P06576,P98194,Q9Y5K8 19 +Transition metal ion transmembrane transporter activity 0.7901750921898182 2.45470593989993 0.0140999875569669 0.9999999978363584 0.0457153722747798 8 Q8N4V1,P35670,Q6NXT4,Q15043,P98194,Q9HD20 6 +Protein carrier chaperone 0.7398256025848106 2.453754812992885 0.0141373338241823 0.9999999979485032 0.0457153722747798 13 P40855,Q8N4V1,Q8N8Q8,Q8N766,Q15006,Q9NPA0,Q9Y5J7,Q15070 8 +Anion cation symporter activity 0.7407948568088787 2.4531482835283493 0.0141611949305069 0.9999999980170936 0.0457153722747798 3 P55011,Q15043 2 +Lipid binding 0.3927001338316438 2.452508384130657 0.0141864073393622 0.9999999980870798 0.0457153722747798 156 P04062,Q15067,Q99623,O60443,Q9BQE5,P56589,O14773,Q9NZD2,Q9NV70,Q9UJZ1,Q9Y3E7,Q99584,O43633,Q5T8D3,Q9NQZ5,P07602,P45880,Q9H490,O75131,Q14108,P11182,P21796,Q92783,Q9NWW5,P30536,P05023,Q9NZJ7,O75477,O00560,P60033,O60313,O94905,O14735,O15173,Q9NQ11,Q9BWH2,O00264,Q9H4A6,O43292,Q8NFH5,O60749,Q9UM22,Q9H4L5,O15118,Q96D53,P50897,Q92643,Q9UNH7,Q9Y371 49 +Phosphatidylglycerol binding 0.7661807790568912 2.449940162538925 0.0142879956784112 0.9999999983449388 0.0457280955083548 4 O60313,O60443 2 +Cardiolipin binding 0.7661807790568912 2.449940162538925 0.0142879956784112 0.9999999983449388 0.0457280955083548 4 O60313,O60443 2 +Solute sodium symporter activity 0.7378725891291653 2.4382001654050147 0.0147605981406775 0.9999999991562972 0.0467086495217386 3 P55011,Q9Y6M7 2 +P type potassium transmembrane transporter activity 0.7099035933391877 2.4257733250439664 0.0152758080777479 0.9999999995954022 0.0481222205139818 2 P05023 1 +L serine transmembrane transporter activity 0.731151373465811 2.4037142044586 0.0162294557573878 0.9999999998962924 0.0501151326134724 3 Q15758,Q96QD8 2 +Molecular carrier activity 0.5222759867629402 2.3940924271392494 0.0166615495633772 0.9999999999440572 0.051114907808042 33 O75880,P40855,Q8TEX9,Q8N4V1,Q15070,Q5J8M3,P52292,Q8N8Q8,Q8N766,Q15006,Q9NPA0,Q9Y5J7,O43819 13 +Clathrin heavy chain binding 0.7921268002189598 2.392039251461438 0.0167550504021054 0.9999999999510534 0.051114907808042 6 Q9NUN5 1 +Manganese ion transmembrane transporter activity 0.7545360260732749 2.3919157020150985 0.0167606914620253 0.9999999999514464 0.051114907808042 4 Q9HD20,P98194 2 +Nadplus kinase activity 0.7288146318731754 2.3916901148719307 0.0167709956932504 0.999999999952156 0.051114907808042 3 Q53H12 1 +Cation channel activity 0.605964426897338 2.3845396086013544 0.0171005070469258 0.9999999999701256 0.0514508982508482 21 Q96ER9,P24539,P00846,P56385,P06576,O75964 6 +Structural constituent of eye lens 0.7270079755528468 2.3823814450985794 0.0172010696473199 0.9999999999741256 0.0514508982508482 3 P08670 1 +Proton channel activity 0.750319123463481 2.374538719292143 0.0175708932467537 0.999999999984752 0.0517549371314235 11 O75964,P00846,P06576,P24539 4 +Proton transporting atp synthase activity rotational mechanism 0.750319123463481 2.374538719292143 0.0175708932467537 0.999999999984752 0.0517549371314235 11 O75964,P00846,P06576,P24539 4 +Thiol oxidase activity 0.7242726288597208 2.368267450912 0.0178716115132056 0.9999999999900824 0.0523116962001122 3 Q6ZRP7 1 +Antiporter activity 0.7643753474903524 2.364746574583673 0.0180424124041036 0.9999999999922324 0.0525236956238339 9 O95202,P05141,P51790,P12236,Q02978,P12235,Q9UBX3 7 +Phosphatidylcholine binding 0.7712718537955241 2.3612167230560632 0.0182150821832831 0.999999999993933 0.0528053425350348 8 A0FGR8,P45880,Q14108,P21796,Q9Y3E7,O43633 6 +Long chain fatty acid transporter activity 0.7459884238603067 2.349059347283335 0.0188209067128459 0.9999999999974511 0.0540764293078703 4 P28288,O14975 2 +Lysophospholipid acyltransferase activity 0.7645855599233276 2.3278939591987164 0.0199177351009098 0.9999999999994704 0.0566894138813073 8 Q9NUQ2,Q96N66,Q92604,Q643R3,Q86UL3,Q8NF37 6 +Cholesterol binding 0.6821627644827304 2.326318289828651 0.0200015770195274 0.9999999999995304 0.0566894138813073 15 Q9H4L5,O75477,P60033,O15118,O94905,P45880,Q14108,P21796,P30536 9 +L aspartate transmembrane transporter activity 0.7413037123648094 2.3254754216645988 0.0200465526700062 0.9999999999995598 0.0566894138813073 4 O75746,Q15758,Q9UJS0 3 +Acidic amino acid transmembrane transporter activity 0.7413037123648094 2.3254754216645988 0.0200465526700062 0.9999999999995598 0.0566894138813073 4 O75746,Q15758,Q9UJS0 3 +Nadh dehydrogenase activity 0.5245104061513034 2.3130234954960147 0.020721347381416 0.9999999999998328 0.0580855471189389 28 O95169,O43676,O95168,Q9P0J0,O95139,P03915,O96000,O95167,P03886,O43674,Q9Y6M9,P56556 12 +Procollagen proline dioxygenase activity 0.7375036539023667 2.3062952229862903 0.0210941418890828 0.999999999999902 0.0586876620874483 4 P13674,O15460,P07237 3 +Peptidyl proline dioxygenase activity 0.7375036539023667 2.3062952229862903 0.0210941418890828 0.999999999999902 0.0586876620874483 4 P13674,O15460,P07237 3 +Pyruvate dehydrogenase acetyl transferring kinase activity 0.7115721800116885 2.302413400831081 0.0213118699606522 0.9999999999999284 0.0591762397128783 3 O14874,Q15118 2 +Mannosyltransferase activity 0.7548902338820687 2.3015089849790797 0.0213628781091765 0.9999999999999334 0.0592008752335169 5 Q6ZXV5,Q2TAA5,Q9BT22 3 +Oxidoreductase activity acting on diphenols and related substances as donors 0.7332112949054967 2.284576434610542 0.0223376760264637 0.9999999999999836 0.0614176806598465 4 Q9UDW1,P08574 2 +Ubiquinol cytochrome c reductase activity 0.7332112949054967 2.284576434610542 0.0223376760264637 0.9999999999999836 0.0614176806598465 4 Q9UDW1,P08574 2 +Serine transmembrane transporter activity 0.7313650979245843 2.275217342425876 0.0228928950279558 0.9999999999999926 0.0620936631549768 4 Q15758,Q96NB2,Q96QD8 3 +Nadp retinol dehydrogenase activity 0.7672415612897372 2.271368296864365 0.0231246919352499 0.9999999999999948 0.0624811387865886 6 Q9Y394,Q6UX07,Q8NBN7 3 +Peptide antigen binding 0.7493072484989166 2.251248028695012 0.0243698324670906 0.9999999999999992 0.0652183135547855 8 Q03519,P10321,P30511,Q15392,P55899 5 +Mhc protein binding 0.7257903919052214 2.24600348851755 0.0247037844581163 0.9999999999999994 0.0659863444175922 11 Q9BUN8,P51572,P60033,Q03519,P06576 5 +Lipid transporter activity 0.5560545379427992 2.2159873241648125 0.0266923702785688 1.0 0.0694495930396097 23 P28288,Q4KMQ2,P30536,Q9H4L5,Q9BZF3,O15118,P17900,O14975,P11166,Q9BZF1,Q9NZD2,Q96GC9,Q96AA3,P33527 14 +Amino acid transmembrane transporter activity 0.7106947699896584 2.207672624363887 0.0272671024992949 1.0 0.0701653461749257 12 O75746,P30825,Q9Y619,Q96QD8,Q96NB2,P08195,Q15758,Q9UJS0,Q96H78,Q9H936 10 +L amino acid transmembrane transporter activity 0.7324355971896884 2.201982874856825 0.0276665181699915 1.0 0.0709333175708725 9 O75746,P30825,Q9Y619,Q96QD8,P08195,Q15758,Q9UJS0,Q9H936 8 +Solute anion antiporter activity 0.7338109714228984 2.196295839810229 0.028070775313937 1.0 0.0718386872788371 5 P05141,P12235,P12236 3 +Iron ion binding 0.5270005243959733 2.1937460880198443 0.0282536685296663 1.0 0.0721752805166932 25 O00767,Q16850,O75845,Q9BU89,P22830,Q6PK18,Q15800,Q6UW02 8 +Acetylgalactosaminyltransferase activity 0.7150989562551752 2.192299941866794 0.0283578559586517 1.0 0.0723099593863986 4 Q10472 1 +Sterol binding 0.6129591364528654 2.1882374361867805 0.0286523114969969 1.0 0.0727935164668734 18 Q9H4L5,O75477,P60033,O15118,O94905,P45880,Q14108,P21796,P30536 9 +Hexosyltransferase activity 0.4810386392642662 2.1859486414167417 0.028819362997261 1.0 0.0727935164668734 39 Q9Y673,P04062,Q2TAA5,Q8NAT1,O43505,Q96L58,Q9BYC5,P46977,Q9P2E5,O60762,Q13126,Q9BT22,Q10472,Q93063,Q6ZXV5 15 +Neutral amino acid transmembrane transporter activity 0.7315789473684191 2.18507745548045 0.0288831679331815 1.0 0.0727935164668734 5 P08195,Q15758,Q96QD8,Q96NB2 4 +Oxidoreductase activity acting on nad p h 0.4863790776998822 2.1819506673603466 0.0291131738309242 1.0 0.0731735406662765 37 P16435,O95168,O43676,Q9P0J0,O95139,O96000,Q7KZN9,P00387,P03886,Q9Y6M9,O95167,Q13423 12 +C4 dicarboxylate transmembrane transporter activity 0.7417373501023803 2.1458608871621467 0.031884079141863 1.0 0.0783166629271287 6 O75746,Q15758,Q9UJS0,Q02978,Q9UBX3 5 +Molecular transducer activity 0.4571728933278812 2.1430944906145233 0.0321055117703303 1.0 0.0787229389830963 45 Q9UBG0,Q9BUN8,P05556,Q08722,Q15758,O15118,O15173,P10586,O75787,Q9NRA0,Q14108,Q99442,Q9Y6I9,Q6RW13,Q9UGP8,Q9UKV5,Q15629,P30536 18 +Solute proton symporter activity 0.7021338789827678 2.1256192689008455 0.0335349738673853 1.0 0.0815166752312741 4 Q9H936,Q96ES6,O00400 3 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.7012569424145151 2.1210901566553844 0.0339142161447163 1.0 0.0822033471570495 4 Q8TCJ2,P46977,P04844 3 +Anion channel activity 0.7010424453127533 2.1143258631465978 0.0344874448565326 1.0 0.0833990706083104 11 Q9C0H2,P51790,P45880,Q96S66,P21796,Q9Y277 6 +Purine nucleotide transmembrane transporter activity 0.7004666833172444 2.11123844978131 0.0347518214887034 1.0 0.0837501015293797 11 O43808,P12236,Q8TB61,O00400,Q6NUK1,P12235 6 +P type transmembrane transporter activity 0.7343340078823093 2.109079145538178 0.0349377506190751 1.0 0.0840540061982885 6 P16615,P35670,P05023 3 +Lipoprotein particle receptor activity 0.6485539000876474 2.0950069406288807 0.0361703755003763 1.0 0.0861925401148692 2 Q8WTV0 1 +Mhc class i protein binding 0.7110005075449902 2.0909796254339383 0.0365298904348974 1.0 0.0866967838868764 9 P51572,Q9BUN8,P06576,Q03519 4 +Palmitoyl protein hydrolase activity 0.7231498054233225 2.0848016024906633 0.0370873132073339 1.0 0.0877233586806467 7 P50897,Q9NUJ1 2 +Fad binding 0.7025389007104362 2.083434391551789 0.0372116461672629 1.0 0.0878695174201754 10 Q15067,Q14534,O00116,Q8NB78,P00387,Q15392 6 +Acylglycerol o acyltransferase activity 0.7071969558894721 2.071133653735581 0.0383463076319934 1.0 0.0900945856571083 9 Q9NUQ2,Q96N66,Q92604,Q643R3,Q86UL3,Q8NF37 6 +Tap binding 0.7226477793482531 2.0506986925136323 0.0402962983860955 1.0 0.0926601900409639 6 Q03518,P10321,P30511,Q03519 4 +Solute cation symporter activity 0.7031615925058597 2.0500290951261753 0.0403615916762063 1.0 0.0926601900409639 9 Q96QD8,O00400,Q9Y6M7,Q15043,Q9H936,P55011,Q96ES6,Q9BXP2 8 +Long chain fatty acid coa ligase activity 0.7221217584475963 2.0480616576440425 0.0405539582692828 1.0 0.0927891240996078 6 Q9UKU0,O14975 2 +Arachidonate coa ligase activity 0.7221217584475963 2.0480616576440425 0.0405539582692828 1.0 0.0927891240996078 6 Q9UKU0,O14975 2 +Chloride channel inhibitor activity 0.6870593443435012 2.047430034390124 0.0406158799439564 1.0 0.0927891240996078 4 O15400,Q9UEU0 2 +Phospholipid transporter activity 0.7148299799863127 2.042566446971478 0.0410953754288228 1.0 0.0934800849112513 7 Q96GC9,Q9NZD2 2 +Glycosyltransferase activity 0.4131036755808208 2.0383182905593085 0.0415181118547951 1.0 0.0942373944361667 54 Q9Y673,P04062,Q8NBI6,Q2TAA5,Q8NAT1,Q4G148,Q96L58,Q9BYC5,P46977,Q9P2E5,Q13126,Q9BT22,Q68CQ7,Q10472 14 +Oligosaccharyl transferase activity 0.7014619883041182 2.0322491441015473 0.0421284400410926 1.0 0.0952904726965146 5 Q9Y673,Q8TCJ2,P46977,P04844 4 +Copper ion binding 0.6926950369939734 2.031140613476473 0.0422407325803166 1.0 0.0952904726965146 10 O75880,P35670,O43819,Q99584,P00403 5 +Oxidoreductase activity 0.3591597867381384 1.9917925790861903 0.0463938208150889 1.0 0.1026749846602955 247 P21912,O95168,Q8NBM8,Q99735,Q8NCN5,O96000,Q53GQ0,Q9BUP3,Q9UDW1,O14548,Q6PK18,Q9Y6M9,Q6UW02,O43819,P13073,O43676,P16435,Q9Y394,P00374,Q96CU9,Q9P0J0,P09601,O43169,P14406,O95139,Q7KZN9,Q9H3N1,P51648,P00387,P30519,Q96LJ7,Q13423,Q3SXM5,P20674,Q16850,Q14534,Q6NUM9,Q8TED1,O75845,Q6UX07,Q8NBQ5,Q8TC12,Q14739,P03886,Q96JJ7,P03915,Q6IAN0,O95167,P00403,Q9Y320,Q9UHG3,Q9H7Z7,Q9BY49,Q6ZRP7,Q15392,O14957,Q8NBN7,Q15800 58 +Organic cation transmembrane transporter activity 0.6926591590616997 1.9870675621121832 0.0469149103235408 1.0 0.1032182618246593 5 Q70HW3,O43808 2 +Sodium ion transmembrane transporter activity 0.7039204212989977 1.9868766462655505 0.0469360682015287 1.0 0.1032182618246593 7 P05026,Q96QD8,P08195,Q9Y6M7,P55011,P05023 6 +Sulfur compound transmembrane transporter activity 0.6974976977508389 1.9860968196611253 0.0470225743545704 1.0 0.1032182618246593 8 Q9HC21,Q70HW3,Q8TB61,O00400,Q9UBX3 5 +Symporter activity 0.6754540128880974 1.9760634935423345 0.0481475864480531 1.0 0.1052348549965983 11 Q96QD8,O00400,Q15758,Q9Y6M7,Q15043,Q9BXP2,Q9H936,P55011,Q96ES6,Q00325 10 +Low density lipoprotein particle binding 0.6269354367513943 1.9752854566318407 0.048235762717302 1.0 0.1052348549965983 2 Q8WTV0 1 +Pattern recognition receptor activity 0.6269354367513943 1.9752854566318407 0.048235762717302 1.0 0.1052348549965983 2 Q8WTV0 1 +Gated channel activity 0.6515600786378308 1.964894873617572 0.0494264061917242 1.0 0.1073141198185314 13 Q9C0H2,Q96ER9,P51790,P45880,P21796,Q9Y277 6 +Myosin v binding 0.7054964495682717 1.9643083721010717 0.049494341382497 1.0 0.1073141198185314 6 P61026,Q15907 2 +Steroid dehydrogenase activity 0.690145993909683 1.9478168791896624 0.0514368783659462 1.0 0.1099981949834923 8 Q53GQ0,Q3SXM5,Q8NBQ5 3 +O acyltransferase activity 0.6149721593317721 1.927975150860563 0.0538582170799941 1.0 0.1131805479744597 15 Q9NUQ2,Q96N66,Q643R3,Q92604,P50416,Q86UL3,Q8NF37,P23786 8 +Udp glycosyltransferase activity 0.5391739303874434 1.9209228826354152 0.0547414304546527 1.0 0.114451949090457 21 Q9Y673,Q8NBI6,Q9NP73,O43505,Q4G148,Q8NAT1,Q96L58,Q9P2E5,Q10471,Q10472,Q93063 11 +Copper chaperone activity 0.6370978017504887 1.9055112141751376 0.0567136511284471 1.0 0.1170083404338741 3 O43819 1 +Metallochaperone activity 0.6370978017504887 1.9055112141751376 0.0567136511284471 1.0 0.1170083404338741 3 O43819 1 +Primary mirna binding 0.6140812153082169 1.9033214944486057 0.0569986078124427 1.0 0.1172518945482899 2 P17844 1 +Inorganic anion transmembrane transporter activity 0.535757846050162 1.8965640914100408 0.0578854936199113 1.0 0.1187885646417794 21 Q9C0H2,Q4KMQ2,P51790,P45880,Q96S66,Q15043,P21796,Q9Y277,Q9UBX3,O43681 10 +Exogenous protein binding 0.577898593050219 1.8920989041358272 0.0584778043156808 1.0 0.1195943450706427 17 P60033,O15118,P35613,P11279,Q14108,Q14118,P78310 7 +Tropomyosin binding 0.6300409117475216 1.8669541473338391 0.0619079913232798 1.0 0.1242581825845831 3 P28289,Q9NYL9 2 +Dicarboxylic acid transmembrane transporter activity 0.6733518068871063 1.8597663097833117 0.0629185958235709 1.0 0.1255690726308483 8 O75746,Q9BQT8,Q15758,Q9UJS0,Q02978,Q9UBX3 6 +Structural constituent of muscle 0.6767365381056011 1.846603617119363 0.0648046095846848 1.0 0.1277005280034812 7 P60660,P09493,P67936,Q14118 4 +Peptide binding 0.3828136030529258 1.836696209032186 0.0662547552303565 1.0 0.1299364532580191 72 P40855,Q99735,Q9NZ08,O14773,Q9Y584,P24390,Q99471,P42892,P52292,Q8TEX9,Q03519,Q9NQX7,O00264,O15212,P55899,Q15388,Q9H7Z7,P10321,P30511,Q15392 20 +Acid phosphatase activity 0.6386128529815496 1.7913886364580778 0.0732309511856281 1.0 0.1413317121096257 4 Q9NPH0 1 +Amyloid beta binding 0.6392532655299213 1.7768308748545438 0.0755960703538323 1.0 0.1433366786061193 11 Q9NQX7,Q99471,P30533,O00264,O15212 5 +Scavenger receptor activity 0.650608915570359 1.7680922343160632 0.0770454854790025 1.0 0.1451057735898105 5 Q14108 1 +Chloride channel regulator activity 0.6498804672464238 1.7642538371178684 0.0776892522569721 1.0 0.1461223553159917 5 O15400,Q9UEU0 2 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.4537705496823406 1.7586486405238193 0.0786372058762772 1.0 0.1475103795142449 30 O95169,O43676,O95168,Q9P0J0,O95139,P03915,O96000,O95167,P03886,O43674,Q9Y6M9,P56556 12 +Voltage gated channel activity 0.6407123118040559 1.7499272840555875 0.0801308619994478 1.0 0.1489204512026775 10 P45880,P51790,Q9Y277,P21796 4 +Estradiol 17 beta dehydrogenase activity 0.6422578951289519 1.723998822600155 0.0847080557146124 1.0 0.1551692546010828 5 Q53GQ0 1 +17 beta hydroxysteroid dehydrogenase nadplus activity 0.6422578951289519 1.723998822600155 0.0847080557146124 1.0 0.1551692546010828 5 Q53GQ0 1 +Phospholipid binding 0.3668712908416811 1.6909416664707717 0.0908479443480698 1.0 0.1613063294893031 99 O60443,O14773,Q9NV70,Q9NZD2,Q9UJZ1,Q9Y3E7,O43633,P07602,P45880,Q9H490,O75131,Q14108,P21796,Q92783,Q9NWW5,Q9NZJ7,O00560,O60313,Q9NQ11,Q9BWH2,Q9H4A6,O43292,Q8NFH5,O60749,Q9UM22,P50897,Q92643,Q9UNH7 28 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.6521961779878857 1.6905652922467225 0.0909198582012824 1.0 0.1613063294893031 6 Q9UHG3,Q8NBM8 2 +Galactosyltransferase activity 0.6192679234968768 1.6871769056409238 0.0915693407056195 1.0 0.1616267885570294 4 Q96L58 1 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.5758106923751151 1.6857139446619525 0.0918509096835278 1.0 0.161717453766111 2 P23396 1 +Antigen binding 0.6257570337102772 1.6674897520220897 0.0954170604816904 1.0 0.1663287468694479 10 Q03519,P10321,P30511,Q15392,P55899 5 +Phosphatidylcholine transporter activity 0.5720128542214541 1.663854529089199 0.0961415037848034 1.0 0.1671767485366941 2 P08183 1 +Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor 0.6436145619848267 1.645772180359105 0.0998106719013975 1.0 0.171855384830225 6 Q53GQ0,Q8NBQ5 2 +G protein coupled receptor activity 0.6269514653382275 1.6426801824034434 0.1004491211626066 1.0 0.1726695611198645 5 Q6RW13 1 +Abc type transporter activity 0.617714642252498 1.6228880030145771 0.1046133486095322 1.0 0.1779440130706933 10 P28288,P08183,Q03519,Q03518,Q9NQ11,O75027,Q9HD20,P33527 8 +Quaternary ammonium group binding 0.5923892397136612 1.6218553589671094 0.1048343218505061 1.0 0.1781042590084172 13 A0FGR8,P45880,Q14108,P21796,A1L0T0,Q9Y3E7,O43633 7 +Atpase coupled cation transmembrane transporter activity 0.5499962160574585 1.614216617511806 0.1064804487751291 1.0 0.1798137386166544 16 P35670,Q9NQ11,P06576,P36543,P98194,Q9HD20,P16615,Q9Y5K8,P05023 9 +Lamin binding 0.6121007605332167 1.5916456113811417 0.1114643554123235 1.0 0.1862157186139294 10 P42167,Q14739,O94901,Q5SNT2 4 +Snare binding 0.4252256815311239 1.5890113722546213 0.112057825252742 1.0 0.1863209993847367 35 P56962,O95721,O15400,O43752,Q9P253,Q9UNK0,O60499,Q12846,P49755,Q9BVK6,Q13190,Q9UEU0 12 +Serine hydrolase activity 0.4914150410671771 1.5748588815858011 0.1152890215560162 1.0 0.1901186329650268 21 Q6NTF9,Q2T9J0,Q5JRX3,Q16740,O43464,Q9HB40,P53634,O14773,Q9H300,P67812,P10619 11 +Syntaxin binding 0.5000505300245336 1.565472298785191 0.1174722077023229 1.0 0.1928136119413127 20 O95721,O15400,O43752,Q9P253,Q9UNK0,O60499,P49755 7 +Lipid transfer activity 0.6205399407530691 1.5500624133421832 0.1211265364030567 1.0 0.1981173267127993 7 Q9NZD2 1 +Cytoskeleton nuclear membrane anchor activity 0.593598707239855 1.5472636017615964 0.1217996948386344 1.0 0.1985250246499783 4 O94901 1 +Mannose binding 0.6184164147231964 1.5386943649910854 0.1238789286602246 1.0 0.2016800634618952 7 O75503,P49257,P35613 3 +Metalloendopeptidase activity 0.5644874911181783 1.533495949953059 0.1251537037852979 1.0 0.2024424944163854 14 P22695,Q5JRX3,Q96TA2,P42892,P52888,O75844,Q99797,Q10713 8 +Growth factor receptor binding 0.5119883938177108 1.5164267198627963 0.1294114869236691 1.0 0.2077978732888629 18 O00560,Q3ZCQ8,Q9NZ08,P05067,O60749,Q92542,Q9Y639 7 +Cytokine activity 0.6160477960242169 1.5006318653767403 0.133450804720939 1.0 0.2125831979965072 6 Q92520 1 +Potassium ion transmembrane transporter activity 0.6142847479323327 1.4912875796277751 0.1358860084303514 1.0 0.215485148808853 6 P55011,Q96ER9,Q9BXP2,P05023 4 +Rna polymerase ii ctd heptapeptide repeat phosphatase activity 0.5416301489921254 1.4873807629957678 0.1369142747166918 1.0 0.2168709762987057 2 Q05D32 1 +Laminin binding 0.5822886862948484 1.4850639793574738 0.137526876796463 1.0 0.2173512507300681 4 Q14118 1 +Extracellular matrix binding 0.5822886862948484 1.4850639793574738 0.137526876796463 1.0 0.2173512507300681 4 Q14118 1 +Acyltransferase activity 0.3496602913699289 1.4688140149108757 0.1418832416707687 1.0 0.2222362926950167 61 Q96N66,P27544,Q92604,Q9NUQ2,Q9NXS2,Q643R3,Q96G23,P50416,Q86UL3,Q9UJ14,Q969G3,P11182,Q9BWD1,Q8NF37,O15269,P23786 16 +Prenyltransferase activity 0.6087464727794908 1.4618887326020094 0.1437717030897343 1.0 0.2246932623371264 6 P37268 1 +Cargo receptor activity 0.5967421535341138 1.4480040983137443 0.147615904418221 1.0 0.2284144776515424 8 O15260,Q14108 2 +Vitamin transmembrane transporter activity 0.6003539604320222 1.4415657365135734 0.1494249201913109 1.0 0.2301995755140261 7 Q9HC21,P11166,P04062,Q9H2D1 4 +Alcohol dehydrogenase nadpplus activity 0.5946036128048326 1.4362931528527605 0.1509189415973637 1.0 0.2315020235285005 8 Q9Y394,Q6UX07,Q8NBN7 3 +Protease binding 0.4160647563462105 1.4047445124067233 0.1600972642993423 1.0 0.2431747636114335 28 Q6NTF9,P46379,Q9NZJ7,Q9GZP9,P05556,Q9BUN8,Q9UKV5,P07602,P14174,Q9Y3E7 10 +2 iron 2 sulfur cluster binding 0.5692404844721671 1.38029730321333 0.1674951249662915 1.0 0.2511206490570564 11 Q8N5K1,Q9NZ45,P22830 3 +Phosphatidylinositol phosphate phosphatase activity 0.5933266055362014 1.379688269659155 0.1676826461801115 1.0 0.2511206490570564 6 Q9NTJ5 1 +Ephrin receptor binding 0.577545573023459 1.3761336008000926 0.1687802744774242 1.0 0.25200455434727 5 P18031 1 +G protein activity 0.510495770963676 1.3566687662638972 0.1748864810085462 1.0 0.2589204487007454 16 P62820,Q9H0U4,P20339,Q15907,P61225,P61026 6 +Signal sequence binding 0.4302159852885956 1.332222837047884 0.1827869743440771 1.0 0.2675163530764878 24 P40855,Q9Y584,Q15388,P24390 4 +Fibroblast growth factor binding 0.5693722032485904 1.3315122939330102 0.1830205025078974 1.0 0.2675794027300686 5 Q99584 1 +Peroxisome proliferator activated receptor binding 0.5147531405200155 1.3291449721889026 0.1838001455842062 1.0 0.2684399215652908 2 P17096 1 +Transferrin receptor binding 0.5810768586072238 1.314053031120312 0.1888283586695669 1.0 0.2742129079502238 6 P60033,O60749 2 +Aldo keto reductase nadp activity 0.5655278927574743 1.3017405203424142 0.1930051028118342 1.0 0.2789837134265711 9 Q9Y394,Q6UX07,Q8NBN7 3 +Serine type carboxypeptidase activity 0.5627227552209213 1.295118720176326 0.195279277978468 1.0 0.2816913609442993 5 Q9HB40,P10619 2 +Oxidoreductase activity acting on a sulfur group of donors 0.4032472699265274 1.2922643354153664 0.1962656184443447 1.0 0.2828237886300558 28 Q9Y320,Q8NBM8,Q9UHG3,Q9H3N1,Q6ZRP7,O43819 6 +Endopeptidase activator activity 0.5616521371532334 1.289251812079377 0.197310557686154 1.0 0.2837475266622788 5 P61289 1 +Proteoglycan binding 0.5458696438351417 1.2827850201599773 0.1995674036550299 1.0 0.2857572292029826 4 O00560 1 +Phosphatidylinositol 3 kinase binding 0.5062810400233824 1.2789217849602408 0.2009246003155615 1.0 0.2861426638073305 2 P50570 1 +Ankyrin repeat binding 0.5030674846625753 1.259835034166462 0.2077288785861353 1.0 0.2936207992087727 2 Q9C0C2 1 +Endopeptidase activity 0.3325537542846466 1.2335716649059816 0.2173625569269803 1.0 0.3038750173954302 65 Q6NTF9,O75844,P22695,Q16740,Q9NZ08,Q92643,O14773,Q9H300,P67812,P42892,O43292,Q9BXS4,P49721,Q92542,Q10713 15 +Signal recognition particle binding 0.5563682283130978 1.180919167759093 0.2376348360103151 1.0 0.3289428025561504 6 Q9BUN8,Q9GZP9 2 +Structural constituent of postsynapse 0.5170267992808013 1.120943880822211 0.2623117509120729 1.0 0.3553982738972637 4 Q16352 1 +Protein disulfide isomerase activity 0.526729137963842 1.107389300539069 0.268125649839394 1.0 0.3601496539429719 10 Q9BS26,Q92643,Q6ZRP7,P07237,Q96JJ7 5 +Misfolded protein binding 0.4812367163767559 1.0861427431019424 0.2774158443412648 1.0 0.3694495367767555 15 Q6NTF9,P48723,Q9BUN8,Q9GZP9 4 +Fatty acid ligase activity 0.5345737265795973 1.082638749622151 0.2789688006405559 1.0 0.3711658758522548 7 Q9UKU0,O14975 2 +Amide transmembrane transporter activity 0.5335368715126967 1.0769388403160205 0.2815075896886567 1.0 0.3738356933010989 7 O00400,Q9H2D1,Q03519 3 +L ascorbic acid binding 0.5323370575135766 1.070342401683545 0.284465215142748 1.0 0.3770505917693971 7 P13674,Q6PK18,O15460 3 +Thiolester hydrolase activity 0.4463956277258871 1.0585395699136266 0.2898095206163713 1.0 0.3830502130442161 18 P28288,Q68D91,O14734,Q9UMR5,P50897,Q9NUJ1 6 +Insulin like growth factor receptor binding 0.4871420222092283 1.056525744233587 0.2907280854810607 1.0 0.3839031579895586 3 P46108,Q04917 2 +Palmitoyl coa hydrolase activity 0.5275120341889591 1.0438087953379138 0.2965738615184576 1.0 0.3894264256387224 7 Q68D91,P50897 2 +Ubiquitin specific protease binding 0.5144680502646727 1.0368989120275856 0.2997829710407864 1.0 0.3921741846483286 10 Q6NTF9,Q9BUN8,P46379,Q9GZP9,Q9UKV5 5 +Calcium ion transmembrane transporter activity 0.4936243569599344 1.0269656307360624 0.3044366481043252 1.0 0.3970314302513596 13 O95202,P98194,P16615,Q9UM00 4 +Lysophospholipase activity 0.527869507666824 1.0265630713767924 0.3046262503992638 1.0 0.3970314302513596 6 Q8N9F7 1 +1 acylglycerophosphocholine o acyltransferase activity 0.4817849663210026 1.025439255742188 0.3051559735151405 1.0 0.3973532370609569 3 Q8NF37 1 +Long chain acyl coa dehydrogenase activity 0.4995615317158726 1.0225737494895732 0.306509426430736 1.0 0.3987460593844297 4 Q9H845,P49748,Q9NZ01 3 +Inositol phosphate phosphatase activity 0.4952648993088935 0.998362533458926 0.3181035945885617 1.0 0.4126828720193252 4 Q10713 1 +Gdp binding 0.3769489290256904 0.9658836831743404 0.3341023879728348 1.0 0.431050371994337 25 P20339,P61019,Q15907,P61225,Q9NP72,P61026 6 +Metalloexopeptidase activity 0.4068278234870714 0.9385495193431684 0.3479620811630326 1.0 0.4481088212961144 21 O75844,Q969V3 2 +Glutathione peroxidase activity 0.5082792831057616 0.9203560446075834 0.3573867305450213 1.0 0.4585647090554839 6 Q8TED1 1 +Collagen binding 0.4961339681373276 0.9096367051124844 0.3630141344882376 1.0 0.4643557088038775 9 Q9UBG0,O75718,P05556,Q53GQ0,Q92791 5 +Phosphoric diester hydrolase activity 0.4800893610242937 0.8614377315393029 0.3889970024426146 1.0 0.4884706459937449 11 Q8N9F7,P09601 2 +Oligopeptide binding 0.4780027718737122 0.8280387131781948 0.4076485759220492 1.0 0.5059595840728613 5 Q9H7Z7 1 +Structural constituent of presynaptic active zone 0.4291557113643026 0.8187575477276854 0.4129247560602407 1.0 0.5111535526560689 2 Q8IUD2 1 +Metallopeptidase activity 0.3345128559439032 0.8168011372553861 0.4140420822165014 1.0 0.5116351147882009 41 Q969V3,Q9NXS2,P22695,Q9NZ08,O75844,Q10713 6 +Amide binding 0.3009441473370847 0.7785641479406308 0.4362365052967019 1.0 0.5342428146511652 107 P40855,Q99735,Q99623,O14773,Q9NZD2,Q9Y584,P24390,P00374,P07602,P45880,P21796,P52292,Q9NZJ7,Q03519,Q9NQX7,O00264,P55899,Q15388,Q9UM22,Q9H7Z7,Q9Y680,P30511,Q15392 23 +Coa hydrolase activity 0.47261550122528 0.7769231719770896 0.4372040991694148 1.0 0.534482559829113 9 P28288,Q68D91,P50897 3 +5 3 dna helicase activity 0.4554223911137132 0.7746161256100749 0.4385665257529347 1.0 0.5348836533705498 4 Q9Y230,Q96RR1,P18074 3 +Serine type exopeptidase activity 0.47381544721349 0.7493435461026738 0.4536501677504958 1.0 0.550888924537119 7 Q9HB40,O14773 2 +Modified amino acid binding 0.3841673112255545 0.7136557610269147 0.4754400681833264 1.0 0.5717018900115121 20 P00374,Q9H7Z7,Q14108 3 +Aspartic type peptidase activity 0.4566282111834276 0.7111069934810987 0.4770179365919149 1.0 0.5728292315484107 5 Q8TCT9,Q92542 2 +Protein membrane adaptor activity 0.4498529258696327 0.7070399582625237 0.4795416464732427 1.0 0.5748771444495785 12 Q9NUN5 1 +Phosphatidic acid binding 0.4521940144491288 0.6870290738750079 0.4920644073111024 1.0 0.586387185981424 5 O60313 1 +Peptide transmembrane transporter activity 0.4372972705227357 0.6740394961418776 0.5002862038273648 1.0 0.5936673280214928 4 Q03519,Q03518 2 +Hormone binding 0.4569025560132352 0.6726017155118761 0.5012007100348415 1.0 0.5942506308851918 8 P42892,P30536 2 +Guanylate kinase activity 0.4340836012861875 0.6563443220727395 0.5116026059274488 1.0 0.6045430288713756 4 O14936,Q9UDY2,Q00013 3 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides 0.4401213396687212 0.6501869169943462 0.515571490901281 1.0 0.6082098612227538 12 Q9Y2B2,Q13510 2 +Exopeptidase activity 0.3244184503763543 0.622170880403838 0.5338295114471512 1.0 0.6239352254404498 33 O75844,Q969V3,Q9NXS2 3 +N6 methyladenosine containing rna binding 0.4400584795321655 0.6215608676795606 0.5342306592205417 1.0 0.6239352254404498 5 P07910,P22626,Q96MU7,Q9H6S0 4 +Complement binding 0.4109007176390734 0.6180239322264293 0.5365595630043956 1.0 0.6256150921337558 3 P35232 1 +Opsonin binding 0.4109007176390734 0.6180239322264293 0.5365595630043956 1.0 0.6256150921337558 3 P35232 1 +Flavin adenine dinucleotide binding 0.3262772896429056 0.6132174498180549 0.5397325681697775 1.0 0.6287929173122202 29 P16435,Q15067,Q14534,O00116,Q8NB78,P00387,Q15392,P09622,A1L0T0,P50336 10 +Beta tubulin binding 0.3874590811090669 0.6030238278594015 0.5464928378970928 1.0 0.6361412073284303 17 O75381,P50402 2 +Atpase activator activity 0.4092458621852514 0.5673401907101527 0.570483076175273 1.0 0.6613273284045038 14 Q96DA6,O95433,Q96KC8 3 +Acetylglucosaminyltransferase activity 0.4394497469605043 0.5646681499837558 0.5722995017176236 1.0 0.6623400328774803 7 Q8NAT1,O43505,Q93063 3 +Molecular function activator activity 0.3900420090645421 0.5580007995706756 0.5768438381798302 1.0 0.6670498704877872 16 Q96DA6,O95433,Q96KC8 3 +Atp dependent peptidase activity 0.4275864602134685 0.5550812966339869 0.5788390551626161 1.0 0.6682041862077182 5 Q16740,Q96TA2 2 +Peptidase activator activity 0.423591549312315 0.5546945087755879 0.5791036327975305 1.0 0.6682041862077182 12 Q9UL46,Q9BXK5,P61289 3 +Translation repressor activity mrna regulatory element binding 0.4373302322652965 0.5534716204306463 0.5799405083849896 1.0 0.6684302003945122 7 P00374 1 +Disulfide oxidoreductase activity 0.3418158631233824 0.5491439011580672 0.5829066994408407 1.0 0.6701996012392646 23 Q9H3N1,O43819,Q9Y320,Q6ZRP7 4 +Ribosome binding 0.3096728882867962 0.5408078881923984 0.588640005221293 1.0 0.6751340468048299 39 Q969V3,Q8WWC4,O95202,Q96A33,Q15070,Q9UM00 6 +Sterol transporter activity 0.426140022184392 0.5199083601597704 0.6031274482120756 1.0 0.6889382640146068 9 O15118,Q9H4L5,P30536 3 +Cell adhesion mediator activity 0.3400825305187538 0.4849089520925441 0.627740931925862 1.0 0.7101256113976137 22 Q08722,P05556,P35613,P61026,Q9Y639,P78310 6 +C acyltransferase activity 0.4138195193529263 0.4823813925394744 0.6295350370342379 1.0 0.7115822421827065 11 Q9BWD1 1 +Protein macromolecule adaptor activity 0.2829936994761857 0.4794334406608741 0.6316303083432881 1.0 0.7132473888944071 101 O15400,Q9UKR5,P56589,Q9P2W9,Q92542,Q12981,P07196,O95721,O95249,Q12846,Q9BTX1,P56962,O00560,O60499,O15155,O75396,Q13190,Q9NUN5,O94901,O43752,Q9P253,Q9UNK0,Q9UEU0,Q9UKV5,Q9UH99 25 +Myosin binding 0.4025883787642954 0.4361076851435201 0.6627586015476639 1.0 0.7390284406146569 12 P61026,Q15907 2 +Hydrolase activity acting on carbon nitrogen but not peptide bonds 0.3054222398551176 0.4305789516923585 0.666774548423035 1.0 0.7417404913177863 29 Q9Y2B2,Q13510,P00813,Q68D91 4 +Carbonyl reductase nadph activity 0.3895574902299343 0.4180435052948997 0.6759153091498946 1.0 0.7513140896800649 4 Q9Y394 1 +Carbon sulfur lyase activity 0.4109972522752698 0.4171131607713941 0.676595639002826 1.0 0.7514757887738898 7 Q99735 1 +Heparin binding 0.397772995786788 0.4094808518126566 0.6821868161305935 1.0 0.7570872643471437 12 Q53GQ0,P30533,O14737,P05067 4 +Chaperone binding 0.2878209982854953 0.4016178337899813 0.6879653030241768 1.0 0.7622959390764735 45 Q16611,O43808,Q9UKV5,Q16543,P53634,Q9HAV7,O95433,Q14108,Q9Y5J7,O43615,P55011,O15212,Q96KC8,O95429,P61604,P30040,P05023 17 +Gtpase activity 0.2769124751981638 0.3874683399523811 0.6984095190254416 1.0 0.7684145452081013 93 Q8NHH9,P62820,Q8N8L6,Q9NR31,P61019,Q9NXU5,P63218,Q15907,O60313,P61026,O95140,Q8IWA4,P61225,P20340,Q969Q5,Q9BZG1 16 +Atpase binding 0.2973293974600046 0.3675087525678422 0.7132395643244611 1.0 0.7822807087243309 31 Q93050,P40855,Q8NFQ8,Q9BUN8,Q16740,Q9Y487,O76024,P36543,Q92542,Q9NWS0 10 +Threonine type peptidase activity 0.3957167616549218 0.3595590223380333 0.7191769321798085 1.0 0.78633742390088 9 Q9UJ14,P49721 2 +Glucosyltransferase activity 0.392739949978648 0.3553951144040627 0.7222936084331208 1.0 0.7879056831122165 10 Q9Y673,P04062,Q9Y672,P46976 4 +Channel regulator activity 0.3442831340627678 0.3526269859763165 0.7243681037228962 1.0 0.788943554829976 18 Q9UEU0,Q9HD47,Q9UNK0,O15400 4 +Cell cell adhesion mediator activity 0.3335193072950894 0.3517331590476958 0.7250383903219766 1.0 0.7890619197539714 20 P61026,P35613,Q9Y639,Q08722 4 +Map kinase activity 0.3579777907656378 0.3325775328675144 0.7394532050118936 1.0 0.801026794943493 3 Q16539,P27361 2 +Transmembrane transporter binding 0.2910726868714297 0.3137848350989085 0.7536844629428483 1.0 0.811944680739852 31 Q9HD47,P30536,P16615,P21796 4 +O methyltransferase activity 0.3884344920204045 0.3134732620326426 0.7539211315609964 1.0 0.811944680739852 8 P21964 1 +Scaffold protein binding 0.3378131468171382 0.311027147584581 0.755779983673144 1.0 0.8130711156667437 18 Q9NZJ7,P07602 2 +Transferase activity transferring sulphur containing groups 0.3791489832446293 0.2967430247964783 0.7666627066534835 1.0 0.8210069381464514 11 Q5VV42,Q7LGA3,Q8NCH0 3 +5 deoxyribose 5 phosphate lyase activity 0.3362547472976877 0.2948298807672338 0.7681238389383374 1.0 0.8218940004267047 2 P13010 1 +Signaling receptor regulator activity 0.3475273305132805 0.2925960097697616 0.7698309641007426 1.0 0.8218940004267047 16 P14174,Q92520,P30533,P05067 4 +Growth factor binding 0.3606825108177371 0.2832262985267995 0.777003370041017 1.0 0.8282926668494909 14 O00165,Q92896,Q99584,O00560 4 +Lipase activator activity 0.3457042665108129 0.271257497161206 0.7861929936630405 1.0 0.8342909033962024 3 Q9Y263,Q12846 2 +Guanyl nucleotide exchange factor activity 0.282808297420715 0.2499711632379079 0.8026096492275197 1.0 0.8465965143878866 33 Q9HD47,P49770,P80303,Q02818,Q9NR50,A4D1U4,Q6IAA8 7 +Clathrin binding 0.3013666563321204 0.244994006949421 0.8064610717444416 1.0 0.8497478032361617 23 Q9NUN5 1 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.3588795185225012 0.214539495118645 0.8301263712230138 1.0 0.8736535966804002 5 Q15067,P50336 2 +Gamma tubulin binding 0.3658141974507386 0.2126260926541496 0.8316186177924232 1.0 0.8745689805376906 9 Q96RT7 1 +Apolipoprotein a i binding 0.3187262635115326 0.2081195160563692 0.8351356491738318 1.0 0.8776107607249316 2 Q8WTV0 1 +Insulin receptor binding 0.3655525715195142 0.2048328869391881 0.8377026916805459 1.0 0.8796504348364477 8 O60749,P18031,Q9NUN5 3 +Protein binding involved in heterotypic cell cell adhesion 0.3668821348993716 0.2008118776598312 0.840845675084986 1.0 0.8822913917060532 6 Q08722 1 +Translation repressor activity 0.3605658656700473 0.1954520258990463 0.8450390911020786 1.0 0.8858368835510374 10 Q9BPZ3,P00374,Q14011 3 +Protein self association 0.3404066322028642 0.1746716285226351 0.8613376621720108 1.0 0.9005449164264595 14 P11166,Q9BTV4,P28288,Q9Y282 4 +Fatty acid binding 0.3567554546267567 0.1608439291574818 0.872216325188067 1.0 0.9104486901108724 7 Q15067,P11182 2 +Camp dependent protein kinase inhibitor activity 0.3026584867075583 0.1343903895973927 0.8930938806884834 1.0 0.930168200420548 2 P10644 1 +Cyclin dependent protein serine threonine kinase regulator activity 0.3460076045627288 0.1132893574316399 0.9098011544593478 1.0 0.9468671274188027 6 P42771,P11802,P14635,P49736,O95067 5 +Peptidase activity 0.2533604716137229 0.1103606399769954 0.9121233671512794 1.0 0.948581295964136 122 Q16740,Q9NZ08,O14773,Q9H300,Q92542,Q10713,P22695,P67812,P42892,Q9BT78,Q6NTF9,Q969V3,Q9UJ14,O43292,Q9BXS4,O75844,Q9NXS2,P49721,Q15005 19 +N acyltransferase activity 0.2828692865406415 0.0869464101711935 0.9307141091911568 1.0 0.966484348420972 22 Q96G23 1 +Pdz domain binding 0.3092406596884349 0.080490618103114 0.9358470576945672 1.0 0.9710968360863124 16 Q15067,P51790,P63218,P20020,P78310,Q8IUD2 6 +Camp dependent protein kinase regulator activity 0.3027469316189363 0.0794860749940967 0.9366460071124773 1.0 0.9712085904007604 3 P10644,P54619 2 +Structural constituent of synapse 0.3347950953057478 0.0712137876669749 0.9432276083062756 1.0 0.9773117917922692 7 Q16352 1 +Phosphatase inhibitor activity 0.3233935092740971 0.0671308825788762 0.9464775085985032 1.0 0.9799564477383176 5 Q01105 1 +Hydrolase activity hydrolyzing o glycosyl compounds 0.2839922327372294 0.0660172906926914 0.9473640595022048 1.0 0.9801520645070676 21 P54802,P04062,P17900,O60476,Q9NUJ1 5 +Small ribosomal subunit rrna binding 0.3146198830409369 0.0349564575489008 0.9721144614775334 1.0 1.0 5 P23396,P62263,P82912,Q14011 4 +Cytidylyltransferase activity 0.3126534593552894 0.0280043224996806 0.977658703644037 1.0 1.0 5 Q96BW9 1 +Intramolecular oxidoreductase activity 0.255754805025184 0.0082816864856907 0.9933922457493474 1.0 1.0 25 Q9UHY7,Q9BS26,Q15125,Q9H7Z7,Q92643,P07237,Q6ZRP7,P14174,Q96JJ7 9 +Protein n terminus binding 0.2494759483761124 0.008185552530763 0.9934689469477967 1.0 1.0 42 P40855,O00560,O00165,Q99623,O75381,Q13190,Q969G3,Q9UBU8 8 +Molecular adaptor activity 0.2449980722213447 0.0072876805637049 0.994185323664058 1.0 1.0 127 O15400,Q9UKR5,P56589,Q9P2W9,Q12981,Q92542,Q6IAA8,P07196,O95721,O95249,Q12846,Q7KZN9,Q9BTX1,P56962,O00560,O60499,O15155,O75396,Q13190,Q9NX63,Q9NUN5,O94901,O43752,Q9P253,Q9UNK0,Q9UEU0,Q9UKV5,Q9UH99 28 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..09cd9214d28b0f019e6aeba5fb1698d548b8a7c9 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 cyclic amp phosphodiesterase activity", "3 5 cyclic gmp phosphodiesterase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenosine receptor binding", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Angiotensin receptor binding", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Benzodiazepine receptor binding", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bile acid transmembrane transporter activity", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcitonin family receptor activity", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction channel activity involved in cardiac conduction electrical coupling", "Gap junction channel activity involved in cell communication by electrical coupling", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione hydrolase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H3 histone acetyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "Hypoglycin a gamma glutamyl transpeptidase activity", "I smad binding", "Identical protein binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoic acid responsive element binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor binding", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD13", "ABHD16A", "ABHD6", "ABI2", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG5", "ALG6", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCKDK", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C1orf50", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CD81", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPH", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNTLN", "COASY", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ8B", "COQ9", "CORO1C", "CORO7", "COTL1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRCP", "CRK", "CRKL", "CRMP1", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERG28", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FNDC3A", "FNTB", "FOXK2", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GID8", "GIGYF2", "GJC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS4", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IBTK", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPA1", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRWD1", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED17", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL16", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS2", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDRG1", "NDUFA10", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NENF", "NES", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIT2", "NKRF", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OFD1", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACS1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDSS1", "PDSS2", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX11A", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGL", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTMA", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIDA", "RING1", "RIOX1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAI", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F1", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPIN1", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUFU", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNE1", "SYNE2", "TAB1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMCO1", "TMED10", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM165", "TMEM192", "TMEM201", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TSTA3", "TTC1", "TTC26", "TTC4", "TTF1", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TXNRD2", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCR11", "UQCRC1", "UQCRC2", "UQCRFS1", "URGCP", "UROD", "USO1", "USP10", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UST", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VMP1", "VPS16", "VPS18", "VPS25", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS72", "VRK1", 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0.4720542672282273 3.667860427157979 4.9083023341259215 0.9853391072008848 0.3404582870775928 0.1221811661163811 0.0229352567383845 0.1231026090672371 0.3701963324590363 0.1640104998874151 +Erythema 10 28 2.664789593061094 0.0077036505717962 5.512135922330097 21.009708737864077 0.7860124479392929 0.4207309091489555 2.592436403423807 3.539637263054128 0.9160883902281578 0.3036972678357262 0.0336182176221532 0.2801168002074996 0.1388614812827933 0.0059425292278447 0.0166822263622692 +Bulbar signs 7 15 2.6625326189488403 0.0077555052420994 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 0.0136773168070196 0.1430638950507344 0.266209970857853 0.0070923684446229 0.003914644875648 +Peripheral axonal neuropathy 16 60 2.65814273493168 0.0078572607887656 13.890776699029129 56.6626213592233 0.647996206639266 0.5297865267121298 5.546380992609976 6.858150910061315 0.9851361073340408 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fibers 8 19 2.631657102966973 0.0084969572339066 5.233009708737864 17.730582524271846 1.450228655394427 0.2143723456093393 2.356374883616516 2.3878203593303375 1.2019998086948689 0.268108115907532 0.007660250712326 0.1715759324473242 0.0538434207197609 0.0003172858283449 0.0024204837857025 +Abnormal urine protein level 16 64 2.622133899391361 0.0087381092576357 12.186893203883496 57.883495145631066 0.3263829049450854 0.5953561251667359 5.528524712203877 5.170023700672021 0.8651184877190968 0.3416430341577767 0.0176498002301423 0.5512761203069648 0.4729609888538263 0.106099107430913 0.0142479943638814 +Decreased absent ankle reflexes 7 14 2.6189536832304614 0.0088199921993554 4.54126213592233 13.740291262135925 0.614698131143983 0.4646843865398717 2.302541095049457 2.6371188884218366 0.9410514279256472 0.3107404522460847 0.0001934587418857 1.0 1.0 0.0043549454623746 3.828861199610836e-05 +Abnormal brainstem mri signal intensity 10 24 2.615813444547999 0.008901517774833 6.252427184466019 20.32281553398058 0.9466857218441096 0.334812084954676 2.9078682900486936 2.582646312540884 1.1241621585657078 0.2967087697298931 0.000202036679224 0.0135379522122687 0.0052800410185589 2.4880325513906888e-05 0.0003233683313873 +Hypertrophic cardiomyopathy 33 120 2.610764538622048 0.0090340070914107 26.796116504854368 107.3495145631068 0.4274787301303976 0.4988726739093555 10.944572821213892 9.196568310864103 1.312724112644841 0.3809066370755179 4.7568508568714484e-07 0.0238675471107415 0.0064521859740737 0.0001394688361122 6.253308476813585e-07 +Delusions 11 20 2.609198452097768 0.0090754593622472 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0008347243164173 0.1553991536419083 0.0443091130960601 0.0097601039903573 0.0012514150662819 +Increased cerebral lipofuscin 4 6 2.602804071199421 0.0092464779284493 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 3.8987794627620416e-05 1.0 1.0 6.292953854873037e-05 5.436360967141595e-05 +Visual loss 18 54 2.589801543430501 0.0096031276096191 12.189320388349516 49.779126213592235 0.7709512625515322 0.4025114627500821 4.5744204921606055 5.175300864908489 1.242827263568942 0.3662286004483653 0.0247906939325621 0.5310682828592934 0.4440550029604954 0.0358973877977225 0.0087743377402522 +Centrocecal scotoma 3 5 2.5734458154021733 0.0100691412144884 1.412621359223301 3.4174757281553396 1.047136053030402 0.2605380489375263 1.0285421497043965 0.9530153662170558 1.2330605307472418 0.2744264936628784 0.0116152577017657 0.0516364610584135 0.1008375048293403 0.0020064706347618 0.0013781701696679 +Abnormal circulating lipid concentration 23 79 2.569691386672584 0.0101789148982169 21.0995145631068 75.44417475728156 1.321442689138656 0.3287247628796158 8.33534407984455 6.5596064623065375 1.4065018349702674 0.365722219395451 1.0898269478510598e-05 1.0 0.4978973364926184 0.0093889244601614 3.052157813557787e-06 +Mental deterioration 36 105 2.5696087538451056 0.010181342891085 26.16990291262136 97.51699029126212 1.0638646072845834 0.3178098854339388 8.217921866043707 8.355116022963852 1.9487627742005753 0.3762024781602087 0.0001378476920498 0.1151104414766776 0.0892024106611315 0.0071108725360826 3.1021677367363363e-06 +Focal t2 hyperintense brainstem lesion 10 22 2.5525027451837534 0.010695206671109 5.745145631067961 17.558252427184467 0.7787968952644161 0.3563659539921697 2.720936576360794 2.4403574571781053 1.1656572167307155 0.3009968442621839 5.245360749124857e-05 0.0096266028600564 0.0031841845740684 7.194120758305036e-06 8.543393326442053e-05 +Elevated pulmonary artery pressure 9 26 2.549280955876279 0.0107945298118257 7.422330097087379 24.033980582524272 0.8771466934674594 0.3206437689207037 3.083196929894625 3.78086786662344 1.283632173810104 0.3146045769490745 0.048172616246467 1.0 0.0540767090111314 0.0646269414847783 0.0283278119546019 +Left ventricular systolic dysfunction 1 5 2.542939317113333 0.0109924318031739 2.0024271844660193 6.274271844660194 0.8306323903703577 0.3188570764916028 1.4472920586220064 1.367095356040773 1.072243004538969 0.2702909744520516 0.2629734920461806 1.0 0.191600110602388 0.0983610682747182 0.2898287915273368 +Poor eye contact 15 43 2.542128690028727 0.0110179598403175 9.774271844660197 38.25970873786408 0.6634270903175611 0.4886810186458507 3.917228340019005 4.329065002822378 1.0573021214973186 0.3538640004920722 0.0001100497025051 0.0053226708337122 0.0055234944679999 1.0679246842113709e-05 0.0002102317385037 +Abnormal glycosylation 13 24 2.532061956921007 0.0113393953008276 6.043689320388349 21.259708737864077 0.4368319789530849 0.4886321385908432 2.9093144657736354 3.168109894482179 1.024724777664989 0.3264729071151926 0.000702077694251 1.0 0.3467918934582977 0.0901467992310857 0.0002155385692345 +Abnormality of the optic nerve 66 262 2.530941636032368 0.0113756775525482 55.26699029126213 243.98300970873785 0.3330545875114519 0.7420961441999799 15.8565039079985 26.975306987282984 0.8419720138567378 0.3446258953426701 4.822008537098671e-06 0.0349791968813944 0.1739837812778075 0.0022073933940488 4.34273573723367e-06 +Abnormal circulating long chain fatty acid concentration 3 5 2.529103582223142 0.0114354272892867 2.0728155339805827 4.861650485436893 1.0288291622755297 0.284696092465088 1.384567800831184 1.563474222630441 1.0358408470651057 0.2764983518284591 0.0391533499163334 1.0 1.0 1.0 0.0465653262864464 +Retinopathy 13 28 2.529084094870168 0.0114360622555025 7.716019417475728 27.516990291262136 0.7648928031827923 0.4912060355555205 3.3040774573673595 3.4588008851352714 0.8590527654816497 0.3424638793573584 0.3052238875119256 0.0576595399457578 0.1827953867238 0.587975890572542 0.1995460919996873 +Nasogastric tube feeding in infancy 2 8 2.524869667738489 0.0115741204786534 3.0097087378640777 8.495145631067961 1.0003947416243104 0.2675726652756056 1.510449978803449 1.1668877069106371 1.1016283190777107 0.2724768109071007 0.1421030365983898 1.0 1.0 0.0322769586697076 0.1645088237572309 +Biliary tract neoplasm 2 5 2.52447789029212 0.0115870293370901 1.5995145631067962 3.9029126213592233 0.8419896815342816 0.262356303654682 0.9411311915407056 0.7175276200738594 1.247085844239205 0.254125388145151 0.0087377942346259 1.0 1.0 0.0231366382468947 0.0105668672564949 +Neoplasm of the gallbladder 2 5 2.52447789029212 0.0115870293370901 1.5995145631067962 3.9029126213592233 0.8419896815342816 0.262356303654682 0.9411311915407056 0.7175276200738594 1.247085844239205 0.254125388145151 0.0043638244151776 1.0 1.0 0.0148625463558957 0.0053031795330487 +Reduced visual acuity 34 123 2.464096364331424 0.0137359176305067 25.553398058252423 114.88106796116504 0.4786956822479749 0.5063280215354549 8.433035081523723 11.838637206126975 1.2158495541746812 0.3830713742278179 0.006989295486398 0.2273563825849989 0.4203477564228793 0.0017052611445273 0.0089983830626766 +Fluctuations in consciousness 6 8 2.463460071343994 0.0137603221004243 2.871359223300971 7.104368932038835 1.0899440920546752 0.2545542015295898 1.680977263462837 1.481694234866534 1.1451509420956862 0.2733842157028129 0.0522141841666639 1.0 0.1677870330809631 0.0762921742488627 0.0118865434534573 +Abnormal circulating citrulline concentration 4 6 2.45322070371228 0.0141583440251507 1.519417475728155 4.283980582524272 0.9322911204120568 0.2795135602214257 1.0297099461920487 1.0355035731992424 1.235992875942202 0.2843671782204088 0.1001749696470511 0.0561990347849709 0.1094892401774078 0.0328731354880699 0.018020673376298 +Generalized hyperkeratosis 1 5 2.43540276270234 0.0148752220286763 1.730582524271845 4.912621359223301 1.0808782092062823 0.2557560852549371 1.1711485734328595 0.780301113356215 1.0121219678622022 0.243080004206366 0.0724548439670735 1.0 0.0921025797166938 0.2175647207167039 0.0817606313480972 +Abnormality of the cerebrospinal fluid 45 157 2.434702687086596 0.0149040301176028 33.26456310679612 139.65776699029126 0.6333875809946081 0.5372237787257415 11.267291201647208 15.193792257662585 1.1555525507377646 0.3935007134599857 2.503412665053608e-05 0.0138006515940477 0.0178627621828576 0.0235133540697477 2.290098503836195e-05 +Renal tubular dysfunction 19 45 2.4331538851556296 0.0149679379963454 10.696601941747574 38.30825242718446 0.1801770628462696 0.5211626210818323 4.7262629284387145 5.082774054748088 1.0351767881610885 0.3302619855268031 7.304656299481443e-05 0.0589240460435226 0.0079219249747297 0.0008042937222718 3.521476861973183e-05 +Emg neuropathic changes 11 26 2.4272389095725604 0.015214233286509 6.915048543689321 24.58252427184466 0.5887299592537784 0.4208819793990807 3.046574831105746 2.544837804909062 1.1306803597402475 0.3318248802653038 2.5262095056170573e-05 1.0 1.0 0.0230341265569123 7.133480197010416e-06 +Ventricular preexcitation 4 7 2.4251716679154844 0.0153011494425858 2.5145631067961167 6.497572815533981 0.9841118497305948 0.2225227126053997 1.468861772329754 1.5757549992030588 1.3097679632537274 0.2453287763295943 0.0093740755757518 0.0875404472016038 0.014058804472369 0.0009779431698101 0.0017429018144962 +Abnormality of coordination 104 339 2.412870940997774 0.015827422836032 65.05339805825243 312.07766990291265 0.3537206479527984 0.7134221988982268 20.398983010696288 29.808593053234937 0.9921840157004412 0.3756105558441653 2.843648637748369e-06 0.0887932426829222 0.2453639637561343 0.0067410933722339 2.202445589120185e-07 +Blindness 26 87 2.408747005137137 0.0160073901773345 17.50485436893204 77.9878640776699 0.5531690923808372 0.4517712920686044 6.330499123572238 7.312865926515748 1.2869313794328858 0.374312554297374 0.0017122684423257 0.070184605369373 0.1246977476538018 0.0010990615473311 0.0016022636688124 +Decerebrate rigidity 2 5 2.403952856271494 0.01621886473733 2.070388349514563 4.286407766990291 0.7483196612133007 0.2095871679116443 0.9590634816350864 0.5578301484347907 1.4826535249517825 0.245070013535738 0.0016684345466174 1.0 1.0 0.0082211090226218 0.0020376306093415 +Clumsiness 13 24 2.402500186242789 0.0162834262692457 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 5.529503904155582e-05 1.0 1.0 0.0304079267330467 9.85983881561296e-05 +Fetal distress 11 28 2.401372135881289 0.0163337162726109 6.694174757281553 23.524271844660195 0.315106981366531 0.4342915849252123 3.1374136043562535 2.920781449478041 1.1333892319914325 0.2945358880670072 4.679832144433352e-05 0.01497108596825 0.0061250241039257 3.566586302683105e-05 7.999759770652472e-05 +Metaphyseal striations 2 5 2.4003132591326817 0.0163810465400757 1.300970873786408 5.247572815533981 1.010217520882931 0.3307806984352505 1.0528274594376033 0.9460541108309968 0.8938491735917876 0.283997233679671 0.0063271975141225 0.0424464003246627 0.0031504918831051 0.0188064524051028 0.0076703518288617 +Duplication involving bones of the feet 8 25 2.39915314319473 0.0164330403369947 5.509708737864078 20.026699029126213 0.8286726631699953 0.4291828835649511 2.4019415513574103 3.6259268352065384 0.9263895151182656 0.3280751122544665 0.0950304902260476 0.0875356389619515 0.0766374872717975 0.2394725309204808 0.0622968176328348 +Abnormality of the distal phalanges of the toes 3 6 2.395442607670901 0.0166003128522045 2.094660194174758 5.058252427184466 1.0467054837889296 0.2409661092181722 1.19191069217632 0.9786581135773657 1.170071232541671 0.254087308422285 0.0038108776232482 1.0 0.1349531130589082 0.0051503840765812 0.0048822579474643 +Left ventricular hypertrophy 8 25 2.372331450892241 0.0176762259084075 7.567961165048544 23.54126213592233 0.6997255266541987 0.4097452846499351 3.537969183053948 3.034709621147107 1.2051726960058406 0.3398649994618895 0.0095590643458722 1.0 0.4724360815693985 0.0756483536674149 0.0043720646017646 +Paroxysmal involuntary eye movements 10 24 2.3688504785043865 0.0178434654514831 5.910194174757281 19.138349514563107 0.6558846901538902 0.3953776148518428 2.72692311425057 2.547182946947119 1.094018237549431 0.2977191822416544 6.719774427440803e-05 0.0102371045657047 0.0034893000144238 9.01988158654274e-06 0.000109129133689 +Impaired social interactions 22 52 2.3596849219149427 0.0182904623794391 12.00242718446602 47.49029126213592 0.5604537103987376 0.5219910099489533 4.425488172516818 5.269200019661922 1.0091183008466462 0.3500212759055819 0.00073799564867 0.0131788445501069 0.0172011735219368 0.0001897329755079 0.0013885251034258 +Capillary hemangioma 4 9 2.3580005045195853 0.0183736679864605 2.533980582524272 7.133495145631068 1.1471796350867234 0.2683759543048971 1.4112277515033682 1.3471092449900268 0.9767941621718578 0.2786452679412407 0.0155359980002569 1.0 1.0 0.0449350347407693 0.0203628052401783 +Mixed demyelinating and axonal polyneuropathy 4 6 2.3573936529344635 0.0184037258772562 1.4757281553398058 3.861650485436894 1.0618051586825854 0.3019785112671438 0.9638581472614256 1.1670164407518866 1.082154445030509 0.304718894009896 0.0007024718324135 1.0 0.0921025797166938 0.0231366382468947 5.436360967141595e-05 +Abnormal renal cortex morphology 12 58 2.356581345688157 0.0184440275263029 11.28883495145631 53.067961165048544 0.3684545773204664 0.5543810617665341 5.43153070755638 4.378371679243168 0.93176226686647 0.3550469042424617 0.0370881053470674 0.1322223717798328 0.1338452366906126 0.0148517602359951 0.0117255438058116 +Hamartoma of tongue 2 5 2.346828237628604 0.0189339808744481 0.7936893203883495 2.6699029126213594 0.373145412007678 0.4450003812354766 0.8778056160646752 0.9178737514406594 1.252308467575389 0.3303620236404362 0.1459993121590467 1.0 0.1349531130589082 0.307957256786686 0.1630814235328921 +Abnormality of pulmonary circulation 11 32 2.3446038446269943 0.0190473055633793 8.439320388349515 28.538834951456312 0.8940347945025898 0.342085103264471 3.349932259027002 4.295622811850572 1.233599840087162 0.3264185554851845 0.0533729728018424 1.0 0.0837371519329494 0.1179506058012683 0.0145673757087225 +Cogwheel rigidity 2 6 2.3444898854815213 0.0190531273003145 1.691747572815534 5.41747572815534 0.5245835815764137 0.3763230502268936 1.2788913032023987 1.4212279105346624 1.148580263275354 0.3055796210169491 0.033335161975655 0.0742352733278267 0.1432798584585485 0.0561137872346343 0.0397387250697101 +Pathologic fracture 7 16 2.327433215102578 0.0199422196576541 4.257281553398058 15.072815533980584 0.983166532607372 0.3143076297274698 2.133145812327421 2.2800397788540345 1.0713003315034937 0.2893419439464214 0.0016328261011498 1.0 0.3143397790261298 0.616426174876278 0.0024204837857025 +Abnormal protein glycosylation 12 20 2.325577017013909 0.0200411268431135 4.992718446601942 17.04854368932039 0.4349711267577257 0.4629072595890348 2.62316887373748 2.93994465563356 1.0108477090998502 0.3020677841214376 0.000996431873224 1.0 0.2941077913158182 0.0558093330619567 0.0002645246913318 +Abnormality of epiphysis morphology 21 59 2.325274185089081 0.0200573037463576 14.885922330097088 57.24757281553398 0.6699051414631522 0.4959188251133739 5.664066249559964 8.729587504130462 1.029966158611096 0.3689041276003297 0.0935385554643451 1.0 1.0 0.8461390350243145 0.0450383528263836 +Hyperkeratosis 14 61 2.324191575441714 0.0201152286337196 13.094660194174756 57.89563106796116 0.1723425509703818 0.5977105968768013 4.958396882240626 5.528503400059701 0.8720789465254253 0.3306400628576269 0.0310498843025739 0.5424024223240664 0.4602219852437026 0.1960327110285461 0.0494509389460782 +Lacticaciduria 4 6 2.3124528651910707 0.0207527399535591 1.674757281553398 4.849514563106796 0.7129753583310345 0.3234768766519366 1.205184467740076 1.4436586333991552 1.2463576287305282 0.29112130721695 0.0038108776232482 0.0697581245313758 0.1349531130589082 0.000371706641515 0.0005289198821125 +Sensory neuropathy 12 37 2.30751911680593 0.021025897768675 9.17233009708738 33.75485436893204 0.684837850359792 0.4572087500958895 3.983815730493952 4.346698415431409 1.0448123352909229 0.3439679266340525 0.0197675425998732 0.3041527321586795 0.162236447621752 0.0095088070763824 0.0009220641745238 +Very long chain fatty acid accumulation 3 6 2.3004886883952547 0.0214205494087995 2.1820388349514563 5.470873786407767 0.5842375287416242 0.4040997577361238 1.517972497559233 1.851692013853064 1.0678239713607651 0.3118623380771133 0.1784863028688835 1.0 1.0 1.0 0.1985866733922443 +Abnormal nephron morphology 18 71 2.2980724403560298 0.0215576665152494 13.762135922330096 61.74029126213592 0.4944914809639499 0.5493558844464742 5.9985211204104765 5.603659337738046 0.94366156746724 0.3659654536522077 0.0131198442396315 0.1774838129866865 0.1967242680505404 0.0394842162502369 0.004477789691635 +Abnormal vascular physiology 15 56 2.297123011157744 0.0216117534207187 12.74757281553398 50.021844660194176 0.816183607478715 0.4136638745601454 4.907827009322534 5.622165606934028 1.2216480011219424 0.371091913776798 0.1575112354152523 1.0 0.2292275647667074 0.2385629344439445 0.0402129266597144 +Macrovesicular hepatic steatosis 3 6 2.293278693578916 0.021831965082439 2.466019417475728 6.87621359223301 0.939079379807938 0.3067324443022926 1.4701927354039712 1.258646689249585 1.014263353538022 0.2700508944960845 0.0087377942346259 0.0470522829573702 0.0921025797166938 0.0231366382468947 0.0105668672564949 +Abnormality of krebs cycle metabolism 2 6 2.289985339094568 0.0220221665458262 1.3203883495145632 4.587378640776699 0.4752105001527039 0.3557087180923267 1.0812936537728817 1.123290901264749 1.229189970223287 0.2910704578268466 0.1302665862694917 0.0652597674910206 0.1265462710440741 0.0439142352380576 0.0277461310389573 +Foot acroosteolysis 1 5 2.2715564585898 0.0231133132735412 1.2572815533980584 4.723300970873787 0.7875306593292697 0.3485009649356967 1.1177388706060134 0.8482653783663339 0.9836751774372468 0.270639905447839 0.0369771588694818 1.0 0.0653907127050202 0.0113265963942617 0.0419919493306108 +Osteolysis involving bones of the feet 1 5 2.2715564585898 0.0231133132735412 1.2572815533980584 4.723300970873787 0.7875306593292697 0.3485009649356967 1.1177388706060134 0.8482653783663339 0.9836751774372468 0.270639905447839 0.0478482703534769 1.0 0.0743799864466655 0.0148625463558957 0.0542215392640632 +Central scotoma 6 10 2.270868897092685 0.0231549156166812 3.657766990291262 9.152912621359222 1.2790732929494344 0.2261272578521709 2.0233738200365714 2.077016218281829 1.2675536526802949 0.279373459017325 0.0065983589427241 0.1221118561195742 0.2297987482657219 0.0004179970223822 0.0002314752232909 +Morphological abnormality of the pyramidal tract 11 24 2.2704969769703194 0.0231774465071519 5.978155339805825 21.21359223300971 0.941567362517309 0.4190895040605777 2.5839325217273803 2.130000617333851 0.9433759961177594 0.3444076850385922 0.2883180959435619 0.0335548880884004 0.1132051672598368 0.4288192611001937 0.3326328598090462 +Incoordination 25 72 2.257264352643104 0.0239915614071017 15.859223300970871 69.11650485436893 0.6868183945924522 0.4621230815272417 5.5138472973140855 6.676725217396416 1.1752874861922693 0.3755559385684158 0.0002463848873018 0.5621314715824117 0.8090425484882432 0.1190379023019694 0.0002123544625109 +Abnormal cellular phenotype 51 196 2.2548494825765557 0.0241427781204004 39.61407766990291 185.5461165048544 0.5974508379603953 0.5924097878960474 13.622479133459526 17.10902530988799 1.1142688852015548 0.3995331163327372 2.072298820577633e-05 0.0039779389779225 0.0002077127202739 0.0001018777766594 1.9789870305380697e-05 +Abnormality of hepatobiliary system physiology 31 85 2.250210418229383 0.0244355912689318 18.737864077669904 78.23543689320388 0.6753867917166245 0.4584905924436965 8.191827759406172 8.347745847320367 1.279744288983872 0.374212423907768 0.0001877543308277 0.0369413340125406 0.0596942273241678 0.0325377851953469 4.343046600534783e-06 +Supernumerary tooth 2 8 2.241577843868395 0.0249886692596414 1.837378640776699 7.182038834951456 0.7585871881827633 0.400000437027925 1.4747917155327317 1.1734803097311852 0.8707169959243988 0.2908701317755205 0.1421030365983898 1.0 1.0 0.1552222190730896 0.1645088237572309 +Abnormal electroretinogram 9 35 2.240811472534012 0.0250382894999308 6.859223300970874 32.19417475728155 0.3723226242578533 0.5367764432246882 4.113037214139201 3.1846362137801685 0.9320732781642423 0.3371359118420042 0.0257867444029995 0.4101596343015291 0.2819243430606499 0.0165617554563997 0.0387230237160692 +Cognitive impairment 53 180 2.23497824743863 0.0254187768548046 40.38834951456311 166.01456310679612 0.9678903819313606 0.4602309002251459 12.35477425089026 15.27402711863426 1.6121748345734526 0.4202585511538368 0.0006245538978598 0.3682790914903757 0.2643455937317487 0.0253346756631174 3.255163127028559e-05 +Decreased activity of mitochondrial complex iv 4 17 2.23311770859951 0.0255411831086334 3.878640776699029 15.9247572815534 0.8034271187166634 0.3445303465767608 2.844656052218728 1.5238137800378977 1.1422119451186783 0.2970372577525856 0.0077400283558172 0.1263420182810564 0.0001376480525375 0.0004989114687539 0.010278445998416 +Optic atrophy 71 201 2.2330262664710663 0.0255472122806712 39.97330097087379 184.7135922330097 0.2254846155090266 0.7235761385556879 12.871537267469767 19.604722774296683 0.8047704019364031 0.3342405671672314 5.247389305109545e-05 0.0256090198210635 0.1732145493062405 0.0116485315881674 5.673320384421914e-05 +Peripheral demyelination 8 20 2.2329573521200508 0.0255517569132421 4.524271844660194 16.973300970873787 0.9472740181618832 0.3208012027704231 2.3341893675900383 2.269845761985369 1.1784704386991718 0.3026863353342601 0.0013931169067679 0.1675604235637086 0.3076603852203092 0.0130060888805635 0.0003924631255206 +Lower limb pain 2 6 2.2301757078175126 0.0257357802995787 1.5825242718446602 4.990291262135922 0.5428874178676697 0.3877045147354496 1.3258027196203157 1.119076818129616 1.1147585770582464 0.3126977330206063 0.195115846167058 0.083126337411673 0.1596960736798767 0.357118555081159 0.0539281835546241 +Impaired proprioception 15 43 2.227019873181333 0.025945945632678 9.813106796116504 38.25485436893204 1.0894904790984437 0.3853358407663543 4.186376779745541 5.223695147901442 1.052731732437443 0.3596256989246241 0.0026240373186339 0.0707254675278004 0.2178091494673695 0.0229258137019905 0.0004223581342339 +Progressive gait ataxia 6 13 2.2249539574866497 0.0260843292023453 3.3810679611650487 11.0873786407767 0.9190295749650902 0.2658532875386696 1.7592835107251577 1.880439920211323 1.2434873962438642 0.2734996669217905 0.0004374409320435 0.1049896535105009 0.1993869387044997 0.0020705519968491 7.568702219565374e-05 +Central apnea 4 8 2.2178419749181075 0.0265656090013184 2.6140776699029127 7.645631067961165 0.7865100475706397 0.3005269589284746 1.5309416715650457 0.8593604190958345 1.1613991531101726 0.2793709321885783 0.003884408184972 1.0 1.0 0.1139407547181512 0.0052134507581354 +Focal segmental glomerulosclerosis 6 25 2.2105172617587674 0.0270692838681025 5.546116504854369 21.611650485436893 0.6827474585317643 0.4280798303492368 2.9461690553889595 2.0180400455423047 1.030587218054049 0.3284604148463202 0.0137123465060884 1.0 0.3467918934582977 0.0040251974639471 0.0048940429574069 +Stroke like episode 4 7 2.2073337027403457 0.0272907543753835 1.9320388349514563 5.347087378640777 0.7802983779647638 0.3377286829697849 1.3402806250303152 1.5433591727314462 1.1185957061594276 0.2970042406174105 0.0061836182508931 1.0 0.1515272625734178 0.0074273483269255 0.0010053263520343 +Nephrotic syndrome 6 30 2.205643122461662 0.0274089972371252 6.691747572815534 26.449029126213592 0.5692557086068671 0.4287880468715059 3.1782986616871702 3.4415823902191023 1.075640445131052 0.3251004953320756 0.1558349519511075 0.377722993581858 0.2426635790855314 0.089202410661812 0.1980954333562903 +Abnormal epiphyseal ossification 10 17 2.192112694530852 0.0283713703450498 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.0137123465060884 1.0 1.0 0.6608597677231411 0.0048940429574069 +Episodic vomiting 6 13 2.1913191842873148 0.0284287027397676 4.179611650485437 11.12378640776699 1.060494846441687 0.2663322982599159 1.9809215871966128 1.7630834730718608 1.1982900451883365 0.2840581402107739 0.011974403322512 0.1389130578490434 0.0354914601129098 0.0063239101987386 0.0033138804057902 +Limb pain 3 10 2.1844884226597645 0.0289263770867647 2.8325242718446604 9.106796116504857 0.4680060334502877 0.4457088303503553 1.9690839713694492 1.4204649953771176 0.9800629794123372 0.3048744760919478 0.1529041918061997 0.134742527043449 0.2518545844225215 0.5213399099817488 0.0553856285019619 +Multiple lipomas 3 8 2.1629396029808734 0.0305458252565746 2.1092233009708736 5.934466019417476 0.2697827106530787 0.5223472039991977 1.4532228591279508 1.612474567063879 0.8947178928698498 0.299311364990647 0.3140784970516614 1.0 1.0 1.0 0.0308662830144804 +Abnormal csf protein level 6 13 2.143895074607467 0.0320412949449238 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 0.007660250712326 1.0 0.3143397790261298 0.0142235096743441 0.0024204837857025 +Hallucinations 20 49 2.136669182881337 0.0326249082239 11.20388349514563 45.44660194174757 0.6705549628539956 0.4221278622600144 3.902598644570227 4.462852401771342 1.2595119979903464 0.3693437289960082 0.0054595833108759 0.3837477700868037 0.2497932687322087 0.0343450359550879 0.0010527524380771 +Disproportionate short stature 8 26 2.133800065567003 0.0328591505411532 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.2156969864847197 1.0 1.0 0.3661388620186562 0.1407079899645458 +Vascular skin abnormality 28 128 2.1319544875091103 0.0330105882277267 24.946601941747577 116.29611650485435 0.7757412099244599 0.4861695283888829 8.070806982353375 12.284834935174542 1.190653202647226 0.3932244292288712 0.0468600614656936 0.2363084452452126 0.0512531945094402 0.045431022901068 0.0202231476272173 +Microcytic anemia 4 9 2.131138575672261 0.0330777275396778 2.441747572815534 8.526699029126213 0.6645628317552182 0.3838242289014166 1.6704179043327654 1.438636684975842 1.0496853438983738 0.3012783873714112 0.0031920703745658 1.0 1.0 0.0001885722773553 0.0042957165481444 +Myoclonus 31 102 2.1309636935184924 0.0330921333486025 19.92718446601942 92.40291262135922 0.7794869182612147 0.4142145469430702 6.660238401732631 11.33633180094438 1.369340457412049 0.3858779422292388 0.0013402382663477 0.12452889879729 0.2319671346160944 0.0037872521296203 0.0002887028870912 +Abnormal retinal artery morphology 9 24 2.1286322203692456 0.0332847005862457 6.985436893203883 21.733009708737864 0.6882820766413594 0.2247118762866906 2.318097134221824 2.0518941450352677 1.8438290687413053 0.2835525492265039 0.0069141117915449 0.0239365913088697 0.0832345551471358 0.006984722202598 0.0025854516113679 +Impaired vibratory sensation 12 34 2.128459878538433 0.0332989730832993 7.536407766990291 29.62621359223301 0.76301203268979 0.4693506811924163 3.6948054205684504 4.667704809367026 0.9514363452495296 0.3439929646326011 0.0065633009087611 0.0502821167245636 0.162236447621752 0.1083386684032722 0.0009220641745238 +Leukodystrophy 15 66 2.127466272724915 0.0333813607647672 14.718446601941748 56.94174757281554 0.1148532598751742 0.5363986626245857 6.478744148544089 5.4693767819453125 1.1351385962972955 0.354727749313835 9.735923796891737e-06 0.0832266786690803 0.0714976342213511 0.000693686312984 2.294357613783844e-05 +Abnormality of corneal size 9 46 2.12440420607952 0.033636358596627 9.186893203883496 39.599514563106794 0.4129322337661419 0.6302055507533163 3.5576422674515347 4.631288666862316 0.6773183948297271 0.3099237199270873 0.0796010207678387 0.4752886178187883 0.3665925032588032 0.2206230715633157 0.1121590594963388 +Segmental peripheral demyelination remyelination 4 7 2.122524426067679 0.0337937237381511 1.6601941747572817 4.737864077669903 1.1231406516527276 0.2457358043386077 1.1021021225411718 1.375663406058269 1.1869683790120098 0.2709829643602553 0.0015400390303818 0.0561990347849709 0.1094892401774078 0.0328731354880699 0.0001575214550341 +Hand polydactyly 10 36 2.120259484393146 0.0339841684200203 9.114077669902912 32.17718446601942 0.810453590544338 0.4452800586149166 3.6615419153480793 5.309376559579211 0.948384387998628 0.3474317696921568 0.1261972652317623 0.1553541085541318 0.1655287313812369 0.2797613861439376 0.09799027055034 +Hyperactive patellar reflex 3 9 2.117823413507117 0.0341900256575795 2.6019417475728157 7.691747572815534 0.3382848613247674 0.4892243591973106 1.5908708357450425 0.9973897264247332 0.9635506080031846 0.3114172566013329 0.0188221125346629 0.0607401038440192 0.1180585699575878 0.0382400085743442 0.0027630263410089 +Cytochrome c oxidase negative muscle fibers 1 7 2.113350755751239 0.0345707574899656 2.128640776699029 7.565533980582524 0.5494269119427225 0.4045538407163497 1.5858767129346854 1.5274435957395311 1.011527854197758 0.3026481749587328 0.1784863028688835 1.0 0.1515272625734178 0.062605312422627 0.1985866733922443 +Hepatic failure 20 52 2.101202302890976 0.0356232113469439 12.25242718446602 48.050970873786405 0.7424989852941342 0.3814651163177168 5.527018274076851 5.448329576476532 1.3577793424610205 0.3539023729255708 0.0063357428297865 0.389715394886943 0.628446438408612 0.4507925405900868 0.0001115942849115 +Undetectable light and dark adapted electroretinogram 0 5 2.095629217804463 0.036115095267678 1.279126213592233 4.135922330097087 0.412543295716365 0.4481667231447873 1.2136965974542693 0.7670210145007976 1.12182699850181 0.3345792506830252 0.3100216140704895 0.0378187125466048 0.0743799864466655 0.1781979724676324 0.3285208438252537 +Abnormal left ventricle morphology 9 29 2.093945273183459 0.0362648556483495 8.155339805825243 27.79368932038835 0.5948246759118737 0.4756129570470222 3.598158324912058 3.3281177777105677 1.054918773522773 0.3428402347836221 0.0116093567183215 1.0 0.5484830827387088 0.1374400519295191 0.0061426201605093 +Delayed epiphyseal ossification 3 5 2.090759611936392 0.0365496182518918 1.4684466019417477 3.7524271844660193 0.3792552327947317 0.4646792671243144 0.8876031402193709 0.8515371207404108 1.0241055966891024 0.3068311748639147 0.0149736639257102 1.0 1.0 1.0 0.018020673376298 +Postaxial polydactyly 10 27 2.088618524022278 0.0367420763465522 5.650485436893204 19.983009708737864 0.6872746163829112 0.4733231406937239 2.5138789038041987 4.077192384198938 0.8522298312255787 0.3139153826677744 0.2379532875755148 0.4158765777114258 0.2890592178487741 0.5066574778796971 0.1710514293041205 +Abnormal circulating cholesterol concentration 15 33 2.0872474951344047 0.0368657682141422 9.691747572815531 31.70873786407767 0.976903841313624 0.2790879029908041 4.4525142732793395 3.04459115485426 1.5883623188049951 0.3063455707490317 0.0005199759492152 1.0 0.5166489093314391 0.0095088070763824 5.66670722833113e-05 +Glucose intolerance 29 118 2.081571014592001 0.0373816712660854 22.20873786407767 103.10436893203884 0.162639567282785 0.6875019668611915 8.15892633803843 9.892935615235253 0.7575325941180685 0.3242633087492569 0.0042127371706415 0.150948268095687 0.0525950985873456 0.0082197709100312 0.0048532513143455 +Microcornea 7 33 2.08126649521996 0.0374095201070352 6.223300970873787 27.9004854368932 0.466347775811294 0.5952452592567805 3.105529171282791 3.8348554430650177 0.7011549915883155 0.306673764898096 0.0833534201421295 0.3837477700868037 0.2497932687322087 0.0952407027608542 0.1123195018566599 +Emg chronic denervation signs 7 14 2.073500199863805 0.038125752535383 4.550970873786408 13.815533980582524 0.6176194543661773 0.3415909714455588 2.199917039284479 1.6085184210885628 1.2249413291120588 0.2985007469873863 6.620364061746945e-05 1.0 1.0 0.0195244436529747 1.0761884384293304e-05 +Action tremor 19 63 2.0699471766599733 0.0384572913814549 13.143203883495143 54.47572815533981 1.1235280535029035 0.3645421720231636 5.4627047451961745 5.814853194507433 1.1817578847970691 0.3688885139588422 0.0024032448199062 0.4701418449361933 0.7201177785711877 0.0142393987273455 0.0001932909765279 +Postural tremor 9 23 2.0648481548310165 0.0389373698862745 5.194174757281553 17.851941747572816 1.214872214945056 0.2487017685351703 2.341305968762478 2.2981463861426747 1.2391489410765593 0.2821199379659175 0.0086761605654707 0.1755724648168266 0.3209553841799009 0.0155108289838298 9.884573920484636e-05 +Respiratory distress 18 56 2.0603689557771423 0.0393632823617315 12.805825242718448 52.09466019417476 0.6386570898760532 0.4437575130669694 5.288397728288474 5.051988998968333 1.24726945526474 0.3693239953771813 0.018397496532889 0.4778436071549874 0.7282146293156844 0.2250331644701588 0.0131912585427836 +Muscle stiffness 9 18 2.0533793550073094 0.0400357999719853 5.109223300970874 19.216019417475728 1.2530133657268057 0.2695837776665858 2.5817154639007844 2.4582801786037667 1.0397164239726309 0.2961148999712332 0.1025228220832543 0.2333020504203794 0.4129317333780675 0.1480244683995481 0.0493599670032898 +Mandibular aplasia 2 5 2.046725253361257 0.0406850682894401 1.325242718446602 4.063106796116505 0.7565831459742005 0.3651486413845429 0.9507501837820184 1.3691816201596263 1.0421239864941276 0.2837555523792943 0.4529312896408254 1.0 1.0 1.0 0.4765717690882453 +External ophthalmoplegia 6 16 2.045218647199025 0.0408333068932598 5.0 17.00242718446602 0.5663831977441792 0.4827064568652057 2.377074975025652 3.293490775365303 0.8939003315322738 0.3080856115403083 0.0558142938029935 1.0 0.3593428278464597 0.0247625444605767 0.0228888281479028 +Abnormal enchondral ossification 13 31 2.044671013988569 0.0408873031511531 8.825242718446601 28.097087378640776 0.9354465670440578 0.4238671948965085 3.7994051258084856 4.343870948544361 0.9586864854575652 0.3408490652683477 0.0406191968210128 1.0 1.0 0.8797240361427394 0.0232519938279594 +Abnormal circulating non proteinogenic amino acid concentration 5 9 2.031198948318619 0.0422348170398902 2.162621359223301 6.968446601941747 0.7521093084296674 0.2992197670299059 1.410866607722538 1.225329167014724 1.1887948503174883 0.2730524920497975 0.1459993121590467 0.0697581245313758 0.1349531130589082 0.0498779046475234 0.0334620993119388 +Scotoma 6 13 2.031017600406741 0.0422532092202141 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 0.0333196756054594 0.1755724648168266 0.3209553841799009 0.0026376358858749 0.0028137185393519 +Distal sensory impairment of all modalities 1 5 2.0307938068275133 0.0422759155509142 1.8932038834951457 4.856796116504855 0.0371424606628624 0.5822825420518175 1.3213160647239326 0.522668124281803 0.8184138141839258 0.2990101788986393 0.3413103865779423 1.0 1.0 1.0 0.0675218785318175 +Progressive external ophthalmoplegia 4 10 2.0256234828360777 0.042803383231841 3.378640776699029 10.228155339805824 0.6986896615619974 0.3934319655103426 1.8174798771838792 2.269764004486748 0.9524665755192452 0.2940766219203315 0.0319469097324507 1.0 0.2297987482657219 0.0038040834633598 0.008785557350241 +Horizontal nystagmus 8 26 2.0182781124707376 0.0435623049147673 6.274271844660194 23.053398058252423 1.1086320165192889 0.2915732095622053 2.6115907074401723 2.1860242554539786 1.3408731048130669 0.3129960018850027 0.034447515883227 0.2295798469686227 0.4072036678679048 0.0018561414510811 0.0149380445762777 +Abnormal tissue metabolite concentration 8 16 2.0137013479966 0.0440408984206051 5.895631067961165 14.650485436893204 0.4799987914691458 0.2340469593783387 2.3926019349714145 2.328417679576543 1.7567023743300048 0.2768423789344761 0.0155359980002569 1.0 1.0 0.1899587232036964 0.0203628052401783 +Increased serum pyruvate 15 37 2.0127595524026307 0.0441399309718826 9.303398058252426 32.64563106796116 0.7845790996019184 0.387018609503293 3.945341127018032 3.24570744750092 1.0586848930233297 0.3138975633269482 7.977544627754362e-07 0.0213158974187442 0.0102837000876808 1.3667024405395029e-07 1.6541310305875818e-06 +Abnormality of the gallbladder 9 40 2.0116522397810885 0.0442566084832549 9.223300970873789 38.0752427184466 0.5027702533780772 0.5379447420549962 3.587145439560844 3.3423828325522775 0.8984096284409542 0.3445277538035425 0.0037933384625588 0.0589240460435226 0.1862598674919939 0.0485304500002844 0.0061426201605093 +Abnormal muscle fiber morphology 18 72 2.002576903628954 0.0452227209845157 17.78640776699029 68.04126213592232 1.263675841483234 0.3649599499596623 6.500784844979595 6.6307423444197315 1.1691802531751734 0.3853191125649093 0.0310498843025739 0.1809337840675792 0.2016492336575425 0.0163850552964513 0.011558005258773 +Abnormal peripheral myelination 11 35 1.9985053177650465 0.0456619039934174 7.635922330097087 32.13592233009709 0.6742900044491671 0.4743014543601314 3.568806451618386 4.873244854452022 0.9969709958674222 0.3457305187498817 0.0134772402791995 0.3339036757647639 0.5571911012951047 0.1462824662633921 0.0023620370657113 +Nephropathy 6 22 1.994257546374864 0.0461239161604813 4.953883495145631 20.679611650485437 0.6460031144846833 0.4125859609731191 2.359716427347698 2.5216098734814283 1.0719980152629416 0.3150102108345451 0.0732230498266224 1.0 0.4672829604777532 0.4697159455465771 0.0373784288289189 +Peripheral axonal degeneration 19 76 1.991465912800799 0.0464296891277384 16.691747572815533 71.19902912621359 0.6211832637355972 0.5650732986012978 6.425044282599762 8.4263916789636 0.8780908495791551 0.3675751486040735 0.0031097536245888 0.549073629062907 0.4697928114830948 0.0182651978308217 0.0003697595096921 +Abnormal retinal vascular morphology 16 55 1.9882698176121905 0.0467818569876392 11.550970873786408 50.40291262135922 0.374132464893944 0.4137648703700375 4.646725961814426 4.349733979382428 1.4638612584769457 0.3720428539009304 0.0935967656300776 0.1706177828799348 0.4407901339858018 0.0826500662202803 0.074056167765242 +Functional motor deficit 39 155 1.9677049871346557 0.0491019916844985 29.844660194174757 142.42233009708738 0.5480906983959746 0.6328805215223481 10.059055989942786 15.366123577335584 0.9036149646030954 0.3745397139529565 0.0002693723262933 0.5295725416042785 0.4697579122978281 0.0163934586385327 9.218349099510396e-05 +Posterior embryotoxon 8 19 1.963968401183018 0.049533756480423 5.400485436893204 18.211165048543688 0.5603270949007155 0.5260153972846668 2.4736082204804974 3.2255911781388433 0.9025074564453092 0.3301763927361542 0.0292641972522141 0.2220822570468345 0.3955810682553247 0.3601862036851755 0.0390821401419673 +Duplication of hand bones 12 61 1.963183393151116 0.0496248682981255 13.0 56.39320388349515 0.2378640054223706 0.6719363973824695 5.036758088178839 6.614250020022192 0.7270653331373877 0.3083618448816323 0.1420588473384671 0.2265732568542214 0.2678713267532724 0.4757260887934409 0.1225196952928618 +Impaired vibration sensation in the lower limbs 5 15 1.9600777269086376 0.049986706120549 3.5436893203883497 13.5752427184466 0.6952737045250533 0.4242336391370475 2.2993316843683766 2.2069327415111175 1.0005780794846004 0.3215228956981494 0.0302392362266226 0.01497108596825 0.0538434207197609 0.2436114581565515 0.0390278099301106 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..55b5a29f5dde625d3afbc8f4c06d2a17c6a5fc59 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 4608, + "title": "Average number of proteins per term", + "value": 24.76388888888889 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8bc7dc6d583bdc5b4ef84da4a7111681466532a8 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..63d99a7cc0a5cd59f4b2e6056dca8929f8b16f50 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1652 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Social and occupational deterioration 0.98305579900672 3.7513163019635942 0.0001759086130952 0.5554346395086096 0.0106956839826282 2 Q9BQE5 1 +Negativism 0.98305579900672 3.7513163019635942 0.0001759086130952 0.5554346395086096 0.0106956839826282 2 Q9BQE5 1 +Abnormal activity of mitochondrial respiratory chain 0.5546964021098828 3.705786756010432 0.0002107355511349 0.6213608936073176 0.0112449900507769 58 Q8N183,P21912,Q86Y39,O96000,Q9Y2R0,Q9Y584,Q9Y6M9,P13073,O43676,Q3ZCQ8,Q96CU9,Q9P0J0,Q7KZN9,P20674,Q70HW3,P03886,Q9UBX3,Q9NPL8,Q8IUX1,Q9Y375 20 +Hyperesthesia 0.9430324276950052 3.570489511762096 0.000356314722087 0.8064444688774643 0.01234509954419 2 P07602 1 +Elevated serum acid phosphatase 0.9430324276950052 3.570489511762096 0.000356314722087 0.8064444688774643 0.01234509954419 2 P07602 1 +Muscle abnormality related to mitochondrial dysfunction 0.6395291612659789 3.5421362384396677 0.0003969004255592 0.8394709259425801 0.0123951757740729 40 Q8N183,Q9Y375,Q86Y39,O43676,Q96CU9,P00846,O60313,Q9NPL8,O96000,Q53H12,Q8IUX1,P03886,P03915,Q9Y2R0,Q9Y6M9,Q9UBX3,P12235,P00403 18 +Mitochondrial myopathy 0.6675905601243809 3.5198826913244523 0.0004317377041975 0.863287749634717 0.0126643805834881 33 Q8N183,Q86Y39,O43676,Q96CU9,P00846,O60313,Q9NPL8,O96000,Q53H12,Q8IUX1,P03886,P03915,Q9Y6M9,Q9Y375,P12235,P00403 16 +Polar cataract 0.9214139643587526 3.4710765790705023 0.0005183761442209 0.9083058414292396 0.0136394674602778 2 Q7LGA3 1 +Optic disc pallor 0.549211506424578 3.469745423267769 0.0005209518821633 0.9093882854665508 0.0136394674602778 55 Q8N183,Q86Y39,Q96RT7,O96000,Q8WWY3,Q9H061,Q9Y6M9,Q10713,O43676,Q96CU9,P00846,Q9UG56,O60313,Q96S66,P03886,Q96L58,Q9H6K4,O95140,Q9NPL8,Q8IUX1,Q9Y375 21 +Elevated circulating long chain fatty acid concentration 0.917323984808648 3.4521273432357096 0.0005561851669568 0.9229741529551736 0.0142383402740961 2 P40855 1 +Abnormal tarsal ossification 0.9120654396728032 3.4276970187126423 0.0006087244198758 0.939545013160838 0.014758394120291 2 Q15125 1 +Ambiguous genitalia male 0.9024247735904196 3.382710595731726 0.0007177422413984 0.9634306101443288 0.0154538946930504 2 Q15392 1 +Atlantoaxial dislocation 0.8951212386795273 3.348458128885521 0.0008126255893419 0.976390379711984 0.0157715939910844 2 Q8NCH0 1 +Advanced ossification of carpal bones 0.895121238679522 3.348458128885446 0.0008126255893421 0.976390379712008 0.0157715939910844 2 Q8WVQ1 1 +Phalangeal dislocation 0.895121238679522 3.348458128885446 0.0008126255893421 0.976390379712008 0.0157715939910844 2 Q8WVQ1 1 +Abducens palsy 0.9205319426673284 3.322264151312768 0.0008929012043108 0.983695705826418 0.0165224104296472 3 P07602 1 +Connective tissue nevi 0.8889862693543678 3.319570394755454 0.0009015607122446 0.9843340483534324 0.0165224104296472 2 Q6NUK1 1 +Generalized osteosclerosis 0.8889862693543705 3.319570394755454 0.0009015607122446 0.9843340483534324 0.0165224104296472 2 Q15392 1 +Optic neuropathy 0.6525269833669369 3.2561261440010827 0.0011294356081674 0.9945240009049072 0.0183254904311116 27 Q8N183,Q86Y39,O43676,Q96CU9,Q9P0J0,P00846,Q9NPL8,O96000,Q8IUX1,P03886,Q8N5K1,P03915,Q9Y6M9,Q9Y375 14 +Bilateral tonic clonic seizure with focal onset 0.903572358987393 3.2442331242525664 0.0011776731750765 0.995616535790849 0.0185891229970131 3 P07602 1 +Lingual dystonia 0.8641542506573209 3.201546639940694 0.0013669194461123 0.9981693307832744 0.0199960787545576 2 Q96RL7 1 +Abnormal brain n acetyl aspartate level by mrs 0.8881174937012383 3.172445895684452 0.0015116072208434 0.999061057132386 0.0214322648419892 3 P07602 1 +Reduced brain n acetyl aspartate level by mrs 0.8881174937012383 3.172445895684452 0.0015116072208434 0.999061057132386 0.0214322648419892 3 P07602 1 +Abnormal brain choline level by mrs 0.8881174937012383 3.172445895684452 0.0015116072208434 0.999061057132386 0.0214322648419892 3 P07602 1 +Hypertrophic nerve changes 0.8489628980426531 3.1284586029022097 0.001757257627976 0.999697843705326 0.0230909383399492 2 Q9NR77 1 +Radioulnar dislocation 0.8784336645236708 3.127128842301385 0.0017652254940689 0.9997087553286644 0.0230909383399492 3 Q96L58,Q8WVQ1 2 +Abnormality of the radioulnar joints 0.8784336645236708 3.127128842301385 0.0017652254940689 0.9997087553286644 0.0230909383399492 3 Q96L58,Q8WVQ1 2 +Abnormality of lysosomal metabolism 0.9082139725226568 3.125685215805273 0.001773913231845 0.9997202043133512 0.0230909383399492 4 Q13510,Q9NZJ7,P07602 3 +Deposits immunoreactive to beta amyloid protein 0.8463336254747295 3.115739257624158 0.0018348443349618 0.9997888050604944 0.0236172142332518 2 O96008 1 +Finger agnosia 0.8463336254747295 3.115739257624158 0.0018348443349618 0.9997888050604944 0.0236172142332518 2 O96008 1 +Undetectable electroretinogram 0.9252095118197858 3.1049124400758603 0.001903353601306 0.9998460697266648 0.0240291873830631 5 O43924,O14773,P50897 3 +Ovotestis 0.8437043529068076 3.1029992257505037 0.0019157014154786 0.9998545994796164 0.0241189948702892 2 P53701 1 +Polyneuropathy 0.7121751637406563 3.0737955990781667 0.0021135418693787 0.9999416766227774 0.0258334242283745 21 O95721,Q9NZJ7,P35670,Q9HC21,P00846,O60313,P07602,P03886,Q15041 9 +Increased csf lactate 0.4907455540084683 3.066063419814701 0.0021689730388654 0.999954848294321 0.0261639470238007 61 Q8N183,Q86Y39,Q9HC21,O96000,Q9NX14,O43819,Q9Y6M9,P13073,O43676,Q96CU9,Q9P0J0,P00846,Q7KZN9,P03886,P03915,Q96I36,P00403,Q9NPL8,Q8IUX1,Q9Y375 20 +Retinal arterial tortuosity 0.8623611922852173 3.051333754073445 0.0022782717360301 0.9999727444480818 0.0269186568195559 3 P00846,P03886 2 +Leber optic atrophy 0.8623611922852173 3.051333754073445 0.0022782717360301 0.9999727444480818 0.0269186568195559 3 P00846,P03886 2 +Multiple glomerular cysts 0.8623611922852173 3.051333754073445 0.0022782717360301 0.9999727444480818 0.0269186568195559 3 P00846,P03886 2 +Low plasma citrulline 0.8623611922852173 3.051333754073445 0.0022782717360301 0.9999727444480818 0.0269186568195559 3 P00846,P03886 2 +Biliary tract abnormality 0.6264760414679834 3.0485336318815426 0.0022996117079281 0.999975302622808 0.0270699862187948 26 Q5XKP0,P04062,Q9NZJ7,Q9NUN5,O95202,P09601,P07602,Q14739,Q14108,P14174,O43681,Q10713 12 +Dementia 0.4883499766202909 3.0402595751925214 0.002363743299534 0.9999816342408856 0.027505376576396 64 P21912,P04062,P27544,O76024,O43681,Q9NQZ5,P00846,P07602,Q14108,Q13510,Q9NWW5,Q9NZJ7,P35670,Q96RL7,O60313,Q9NQ11,P03886,P03915,P00403,O96008,O15118,Q8N5K1 22 +Abnormal mitochondria in muscle tissue 0.6243751146470827 3.03338138613085 0.002418297582182 0.9999857251482706 0.0278173705957038 26 Q8N183,Q86Y39,O43676,Q96CU9,Q9NPL8,O96000,Q8IUX1,P03886,P03915,Q9Y6M9,Q9Y375,P00403 12 +Erlenmeyer flask deformity of the femurs 0.8503798947983728 2.994352583565228 0.0027502792247726 0.9999969205089744 0.0298194980417752 3 Q9NZJ7,P07602 2 +Gastric ulcer 0.850379894798363 2.9943525835651785 0.0027502792247731 0.9999969205089744 0.0298194980417752 3 Q8N5K1,O76024 2 +Proximal tubulopathy 0.6160085272650769 2.9931213578990197 0.0027613992110429 0.9999970747444824 0.0298697830152246 27 Q8N183,Q86Y39,O43676,Q96CU9,Q9NPL8,O96000,Q8IUX1,P03886,P03915,Q9Y6M9,Q9Y375,P00403 12 +Fingerprint intracellular accumulation of autofluorescent lipopigment storage material 0.8203330411919434 2.988834186291843 0.0028004406340726 0.9999975576095184 0.0301505384154369 2 Q9NWW5 1 +Duplication of phalanx of hallux 0.8159509202454058 2.967241689314621 0.0030048465277654 0.9999990503550128 0.0308456736129374 2 Q8WVQ1 1 +Partial duplication of the distal phalanges of the hand 0.8159509202454058 2.967241689314621 0.0030048465277654 0.9999990503550128 0.0308456736129374 2 Q8WVQ1 1 +Duplication of the distal phalanx of the thumb 0.8159509202454058 2.967241689314621 0.0030048465277654 0.9999990503550128 0.0308456736129374 2 Q8WVQ1 1 +Decreased circulating total igg 0.8156587788489729 2.965800070481553 0.0030189667533495 0.9999991103522012 0.0308456736129374 2 P60033 1 +Abnormality of the mitochondrion 0.465595748976473 2.954007626045328 0.0031367625423748 0.9999994838761148 0.0316068242740416 98 Q8N183,P21912,Q86Y39,O96000,Q9Y2R0,Q9Y584,P23786,Q9Y6M9,P13073,O43676,Q9BUB7,Q3ZCQ8,Q96CU9,Q9P0J0,P00846,Q7KZN9,P12235,P20674,Q70HW3,P03886,P03915,Q9UBX3,P00403,O75880,Q9NPL8,Q8IUX1,Q9Y375 27 +Progressive peripheral neuropathy 0.8594874253305294 2.900298952724962 0.0037280690915835 0.999999966477344 0.0350224642996365 4 Q9NZJ7,P07602 2 +Anomalous trichromacy 0.8289705715569118 2.891493190349921 0.0038341590166506 0.9999999794778728 0.0358373321475174 3 Q9H6K4 1 +Tritanomaly 0.8289705715569118 2.891493190349921 0.0038341590166506 0.9999999794778728 0.0358373321475174 3 Q9H6K4 1 +Sensorimotor neuropathy 0.5871808458428907 2.8898988436970057 0.0038536580911789 0.9999999812479098 0.0359466730448437 32 Q9NZJ7,Q9NR77,P00846,O60313,P07602,P03886,Q9Y2R0,P05023,P07196,P00403 10 +Multiple myeloma 0.800175284837864 2.889012109017996 0.003864541921478 0.9999999821686484 0.0359753720690316 2 P04062 1 +Stuttering 0.8473934672147395 2.843346431918526 0.004464251707579 0.9999999988882458 0.0398984282386013 4 P00403,P03886 2 +Vascular tortuosity 0.8468284127448227 2.840675428727358 0.0045018104846661 0.9999999990656564 0.0399385178925528 4 P03915,P00846,P03886 3 +Corneal opacity 0.4689201044962869 2.837588375532212 0.0045455761112676 0.9999999992370016 0.0399385178925528 60 Q9Y2B2,P40855,P04062,Q96J42,P56589,Q9NX14,Q9Y5Z9,Q9NVI7,O95202,Q9Y4P3,O60566,P51648,Q14118,Q13510,P35670,O43505,P53701,O75845,P16278,Q15645,O75844,P10619,Q6NUK1,Q8NAT1,P52732,O75381,P02545 27 +Flaring of rib cage 0.789366053169742 2.834956006712598 0.0045831996589245 0.9999999993589602 0.0399385178925528 2 Q96L58 1 +Hypoplasia of olfactory tract 0.8161893629456528 2.8294395611531957 0.0046629606393646 0.9999999995568776 0.0399385178925528 3 O43924,O75665 2 +Y shaped metacarpals 0.8161893629456528 2.8294395611531957 0.0046629606393646 0.9999999995568776 0.0399385178925528 3 O43924,O75665 2 +Central y shaped metacarpal 0.8161893629456528 2.8294395611531957 0.0046629606393646 0.9999999995568776 0.0399385178925528 3 O43924,O75665 2 +Lobulated tongue 0.8161893629456528 2.8294395611531957 0.0046629606393646 0.9999999995568776 0.0399385178925528 3 O43924,O75665 2 +Duplication of the distal phalanx of hand 0.8161893629456519 2.8294395611531806 0.0046629606393648 0.9999999995568776 0.0399385178925528 3 Q9Y2U8,Q8WVQ1 2 +Type ii transferrin isoform profile 0.815897136177677 2.828015046538562 0.0046837605059593 0.9999999995975584 0.0400422419507616 3 O75787,Q9H9E3 2 +Abnormal social behavior 0.4676914106571891 2.8249756967171513 0.0047284202355493 0.9999999996727302 0.0403491860100208 72 Q8N183,Q86Y39,P05067,O96000,Q9NX14,Q9Y6M9,Q9UHX1,O43681,Q5XKP0,O43676,Q2TAA5,Q96CU9,Q9P0J0,Q9Y4P3,Q15907,P07602,Q9NZJ7,P03886,O96008,Q15125,Q9NPL8,Q8IUX1,Q9Y375 23 +Abnormal visual electrophysiology 0.4930586574764439 2.820610436226288 0.0047932371746792 0.999999999757578 0.0408266855839595 53 O75665,Q9NZJ7,P00846,O60313,O95140,P07602,Q8N766,Q53H12,O14773,Q96S66,Q8TC12,P50897,O43924,Q96HR9,P12235,O43681 16 +Absent nipple 0.785860356412512 2.8173440087117276 0.0048422630197098 0.99999999980681 0.0411681697321453 2 Q6NUK1 1 +Absent brainstem auditory responses 0.813490563626665 2.81627394942116 0.0048584219346101 0.9999999998207374 0.041219525687054 3 O60313 1 +Episodic respiratory distress 0.8415667933352937 2.8157604215916976 0.0048661940047216 0.999999999827074 0.041219525687054 4 P03915,P00846,P03886 3 +Hyporeflexia of upper limbs 0.8112215078901277 2.8051877196399317 0.0050287283278156 0.9999999999185344 0.0422066643364557 3 Q9NR77,O75787 2 +Dysplasia of the femoral head 0.8108095087954574 2.8031730868154536 0.0050602504054562 0.9999999999296002 0.0422420903411996 3 O75431 1 +Cutaneous finger syndactyly 0.8102631787259551 2.800500795250039 0.0051023381759358 0.9999999999420686 0.0423324950977473 3 Q9Y2U8 1 +Red green dyschromatopsia 0.8068228498419752 2.7836521040012587 0.0053750653240325 0.9999999999836224 0.0434531596721788 3 Q9H6K4 1 +Gingival fibromatosis 0.8064073974223546 2.7816150266135757 0.0054089159144161 0.9999999999859996 0.0435903208048432 3 Q15392 1 +High frequency sensorineural hearing impairment 0.8339218142151242 2.7794192310501233 0.0054456194082774 0.999999999988189 0.0437552621989298 4 Q9NWM8,O75844 2 +Abnormal pelvis bone morphology 0.7773882559158702 2.7746179033943177 0.0055266597264884 0.9999999999918864 0.0437574708241614 2 P16435 1 +Cervical myelopathy 0.7773882559158618 2.7746179033942786 0.0055266597264891 0.9999999999918864 0.0437574708241614 2 P16278 1 +Hypoplastic hippocampus 0.8047925189947363 2.7736918344965247 0.0055424152326812 0.9999999999924576 0.0438069457842116 3 Q96RL7,Q9HA77 2 +Increased serum lactate 0.4353937125172057 2.7726963920925405 0.0055593962041886 0.9999999999930284 0.0438659207344201 113 O14949,P21912,Q86Y39,O43819,Q9Y584,Q9Y6M9,P13073,Q5XKP0,Q9NVI7,P22695,Q9BUB7,Q3ZCQ8,Q96CU9,Q9P0J0,P00846,Q7KZN9,P12235,P20674,Q70HW3,Q53H12,P03886,Q96I36,P03915,P08574,Q9UBX3,P00403,O75880,Q6P4A7,P14927,Q96DA6,Q8IUX1,Q9BWD1,Q9Y375 33 +Sclerosis of hand bone 0.776511831726568 2.77018467397218 0.0056024517651713 0.9999999999942892 0.0439797235671427 2 Q15125 1 +Pili torti 0.7765118317265591 2.770184673972141 0.005602451765172 0.9999999999942892 0.0439797235671427 2 Q9Y276 1 +Abnormal circulating proline concentration 0.8030614603379129 2.765189775592828 0.0056889688260493 0.9999999999961756 0.0445072467749324 3 P20674 1 +Punctate cataract 0.8018597107034109 2.7592820169226098 0.005792851955334 0.999999999997637 0.0451559520905725 3 Q9H6K4 1 +Abnormal biliary tract morphology 0.6325409508109262 2.7551913486171924 0.0058657819368728 0.9999999999983148 0.0454067818675891 23 Q5XKP0,P04062,Q9NZJ7,Q9NUN5,P09601,P07602,Q14739,Q14108,P14174,O43681,Q10713 11 +Decreased activity of mitochondrial complex i 0.5464267305666912 2.754612980898627 0.005876159806601 0.999999999998394 0.0454067818675891 39 Q8N183,Q9Y375,Q86Y39,O43676,Q96CU9,Q9NPL8,Q70HW3,O96000,Q9HA77,Q8IUX1,P03886,Q9NX14,Q9Y584,Q9Y6M9,P52815,Q9UBX3 16 +Poor head control 0.4592523645647942 2.739478002346658 0.0061536832649695 0.9999999999995564 0.0468697065867434 76 Q8N183,P21912,Q86Y39,O96000,Q9NX14,Q9Y6M9,Q10713,P13073,Q5XKP0,O43676,O95721,P00374,Q9P0J0,Q96CU9,P07602,Q14118,Q9NZJ7,P03886,Q9NWM8,Q9NPL8,Q8IUX1,Q9Y375 22 +Osteolytic defects of the distal phalanges of the hand 0.8230683555433158 2.7275381086755828 0.006380888659021 0.9999999999998452 0.0479659623829839 4 O75844 1 +Abnormal csf metabolite level 0.4584479019699528 2.718692651430901 0.0065540476465963 0.9999999999999308 0.0491074009032783 67 Q8N183,Q86Y39,Q9HC21,O96000,Q9NX14,O43819,Q9Y6M9,P13073,O43676,Q96CU9,Q9P0J0,P00846,Q7KZN9,P03886,P03915,Q96I36,P00403,Q9NPL8,Q8IUX1,Q9Y375 20 +Mitochondrial inheritance 0.840935672514635 2.717479112810274 0.006578130725134 0.999999999999938 0.0492078350347688 5 P03915,P00846,P00403,P03886 4 +Facial capillary hemangioma 0.7923509423606634 2.7123808105128893 0.006680180030171 0.9999999999999614 0.0496488219016581 3 O75665 1 +Happy demeanor 0.7897844710178756 2.6996740809236064 0.0069407433584904 0.9999999999999885 0.0512547201857759 3 Q15907 1 +Alveolar ridge overgrowth 0.7893376418178523 2.6974597202206794 0.0069870737102351 0.9999999999999908 0.0515142970508213 3 Q15392 1 +Hypocholesterolemia 0.8482440089505747 2.6955138291319076 0.0070280160392948 0.9999999999999925 0.0516800174676784 7 Q9NZJ7,Q15800,Q9NVI7,P07602 4 +Generalized lipodystrophy 0.8155843374832453 2.6915647245631527 0.007111769704617 0.9999999999999948 0.0520265660138258 4 O75844 1 +Loss of subcutaneous adipose tissue in limbs 0.813707541574977 2.682517935680945 0.007307023349897 0.999999999999998 0.0532765246777306 4 O75844 1 +Prominent antitragus 0.7586912065439735 2.679496567367301 0.0073732959242207 0.9999999999999984 0.0536747987658914 2 Q92643 1 +Mottled pigmentation 0.7848213484696716 2.6750434048292675 0.0074719575683095 0.999999999999999 0.0540514607139252 3 O75844 1 +Abnormal chorioretinal morphology 0.5593017255884591 2.671330430407802 0.0075551234006667 0.9999999999999992 0.0542479865586536 32 Q5XKP0,P40855,Q9Y619,Q8NAT1,O43505,P53701,Q96J42,Q96RT7,O75381,P56589,Q14118,Q9NX14,Q12768,Q10713 14 +Abnormal choroid morphology 0.5593017255884591 2.671330430407802 0.0075551234006667 0.9999999999999992 0.0542479865586536 32 Q5XKP0,P40855,Q9Y619,Q8NAT1,O43505,P53701,Q96J42,Q96RT7,O75381,P56589,Q14118,Q9NX14,Q12768,Q10713 14 +Erythema 0.5694603347428138 2.664789593061094 0.0077036505717962 0.9999999999999996 0.0551217730354612 28 Q9Y2B2,P98194,Q15125,P53701,P51648,P03886,Q9NX14,P03915,P22830,P00403 10 +Bulbar signs 0.7413548362177158 2.6625326189488403 0.0077555052420994 0.9999999999999998 0.0553210033368332 15 P04062,Q9NZJ7,P00846,P07602,P03886,P03915,O43681 7 +Peripheral axonal neuropathy 0.4522141375638941 2.6581427349316797 0.0078572607887656 1.0 0.0556168412947578 60 Q9NZJ7,Q9NVI7,Q9HC21,Q96RL7,Q8IV08,P00846,O60313,P07602,Q9NQ11,O76024,P03886,P03915,O15269,P12235,P07196,P00403 16 +Areflexia of lower limbs 0.6468491884282314 2.656598031229747 0.0078933497835711 1.0 0.0556168412947578 21 P07196,O75477,Q9NR77,Q96RL7,Q9H6K4,O60313,O75787,Q15041,P12235 9 +Progressive visual loss 0.5733236155428983 2.6565900741420156 0.0078935360691778 1.0 0.0556168412947578 26 O60313,P00846,O95140,P50897,O14773,Q9HA77,Q8TC12,Q969G3,P03886,P03915,Q9NWW5 11 +Congenital craniofacial dysostosis 0.7537248028045682 2.654035891757598 0.0079535366485699 1.0 0.0556989314234305 2 Q6NUK1 1 +Bacterial endocarditis 0.7537248028045634 2.6540358917575695 0.0079535366485705 1.0 0.0556989314234305 2 P04062 1 +Mild postnatal growth retardation 0.7537248028045578 2.6540358917575415 0.0079535366485712 1.0 0.0556989314234305 2 Q9Y3E5 1 +Osteochondroma 0.7537248028045567 2.6540358917575317 0.0079535366485714 1.0 0.0556989314234305 2 Q93063 1 +Atlantoaxial abnormality 0.8071666157093653 2.6509078059713076 0.0080275750709764 1.0 0.0560470695864534 4 Q9NWM8,Q8NCH0 2 +Palmar telangiectasia 0.7505112474437705 2.6375175233379817 0.008351531053101 1.0 0.0580676788883004 2 Q14739 1 +Vegetative state 0.8240206160765207 2.6373852078329914 0.0083547897358817 1.0 0.0580676788883004 5 Q9NZJ7,P07602 2 +Large placenta 0.776738749269452 2.634767065729873 0.0084195040147885 1.0 0.0582538656158356 3 O75844,Q6PGP7 2 +Aortic valve calcification 0.7767387492694512 2.6347670657298643 0.0084195040147887 1.0 0.0582538656158356 3 P04062,O75844 2 +Mitral stenosis 0.7767387492694512 2.6347670657298643 0.0084195040147887 1.0 0.0582538656158356 3 P04062,O75844 2 +Retinal pigment epithelial mottling 0.7764319103490013 2.633234025072641 0.0084576049257698 1.0 0.0584297503717353 3 P00846 1 +Ragged red muscle fibers 0.6705135525149613 2.631657102966973 0.0084969572339066 1.0 0.0586137409189248 19 Q9Y276,P00846,Q70HW3,Q9H2D1,P03886,P03915,P12235,P00403 8 +Leg muscle stiffness 0.802827911619781 2.6298708522810004 0.0085417310718698 1.0 0.0587467116107107 4 P00846 1 +Deformed tarsal bones 0.7481741162722856 2.625482466098668 0.0086526265255757 1.0 0.0593098077487907 2 O75787 1 +Abnormal urine protein level 0.4495206869689381 2.622133899391361 0.0087381092576357 1.0 0.0597130758739301 64 O75665,O95470,O95721,P21912,P35670,O75431,P60033,Q9Y5U9,Q96D53,P09601,Q9Y4P3,Q14108,Q5JRA6,P03886,P03915,P00403 16 +Decreased absent ankle reflexes 0.7523752206216469 2.6189536832304614 0.0088199921993554 1.0 0.0600374849340791 14 P07196,Q96RL7,Q9H6K4,O60313,O75787,Q15041,P12235 7 +Abnormal brainstem mri signal intensity 0.5977831987000402 2.615813444547999 0.008901517774833 1.0 0.0604988110714317 24 Q8N183,Q86Y39,O43676,Q96CU9,Q9NPL8,O96000,Q8IUX1,P03886,Q9Y6M9,Q9Y375 10 +Hypertrophic cardiomyopathy 0.4145492036528368 2.610764538622048 0.0090340070914107 1.0 0.0612186833488542 120 Q8N183,P21912,Q86Y39,O96000,P50416,Q9NX14,Q9H061,O43819,Q9Y6M9,Q5XKP0,O43676,Q9NVI7,Q9BUB7,Q96CU9,Q9P0J0,P00846,Q9Y4P3,Q7KZN9,P12235,Q13423,P53701,O60313,Q53H12,P03886,P13473,Q96I36,P03915,P00403,Q9NPL8,P50402,Q8IUX1,Q9Y375,P09493 33 +Delusions 0.6534125068694125 2.609198452097768 0.0090754593622472 1.0 0.0614092756846336 20 P04062,Q9NZJ7,Q96DF8,Q96RL7,Q9UJS0,P07602,Q9BQE5,P49770,Q9NR50,P21964,O43681 11 +Brushfield spots 0.7981631441380305 2.607190848096655 0.0091288463588072 1.0 0.061679947245431 4 O75381,P40855 2 +Increased cerebral lipofuscin 0.8364816542053792 2.602804071199421 0.0092464779284493 1.0 0.062292061833764 6 O14773,Q9NZJ7,P50897,P07602 4 +Visual loss 0.4652423866279416 2.5898015434305015 0.0096031276096191 1.0 0.0636751390818079 54 Q9NZJ7,P53701,P00846,O60313,O95140,P07602,P50897,O14773,Q9HA77,Q8TC12,Q969G3,P03886,Q9NX14,P03915,Q96JJ3,Q9NWW5,P00403,Q10713 18 +Centrocecal scotoma 0.8106383001125431 2.5734458154021733 0.0100691412144884 1.0 0.0657489380633553 5 O60313,P00846,P03886 3 +Noncompaction cardiomyopathy 0.7910896058580068 2.5726761311641817 0.0100915592939063 1.0 0.0657735576044138 4 Q96DA6 1 +Abnormal circulating lipid concentration 0.443704317077299 2.569691386672584 0.0101789148982169 1.0 0.0659854121548805 79 P40855,P49257,P50416,P37268,P23786,O95470,Q9NVI7,Q9Y4P3,P07602,P22830,Q9NZJ7,Q8N511,O75845,Q14739,O75844,O75880,Q9NUN5,O75431,Q15125,O75381,P50402,Q15392,Q15800 23 +Mental deterioration 0.4285208729080573 2.5696087538451056 0.010181342891085 1.0 0.0659854121548805 105 P21912,P04062,P27544,P05067,Q9BQE5,O76024,O43819,O43681,Q10713,Q5XKP0,O95470,Q9NQZ5,P00846,P07602,Q14108,P21964,Q13510,Q9NWW5,O95169,Q9NZJ7,P35670,Q96RL7,O60313,P17900,Q9NQ11,P03886,P03915,P00403,O96008,O75503,O15118,O95140,P50897,Q9NPL8,Q8N5K1,Q9UBB4 36 +Scanning speech 0.7629108187693576 2.565384392435183 0.0103061559215871 1.0 0.066448735612245 3 O14773 1 +Psoriasiform dermatitis 0.788354513986965 2.5592904738990083 0.0104886061272226 1.0 0.0672116109310749 4 Q15800 1 +Focal t2 hyperintense brainstem lesion 0.6172221408029845 2.5525027451837534 0.010695206671109 1.0 0.0678363272057763 22 Q8N183,Q86Y39,O43676,Q96CU9,Q9NPL8,O96000,Q8IUX1,P03886,Q9Y6M9,Q9Y375 10 +Atrophy degeneration involving the caudate nucleus 0.7869210387322221 2.5522660430782964 0.0107024761021266 1.0 0.0678363272057763 4 P00846 1 +Elevated pulmonary artery pressure 0.5591938602293094 2.549280955876279 0.0107945298118257 1.0 0.068325815072655 26 Q8IZA0,P20674,O96000,Q14108,P03886,P03915,O75844,Q6NUK1,P00403 9 +Nasal regurgitation 0.7323984808647455 2.543764596545551 0.0109664963404558 1.0 0.0691294324717109 2 P53007 1 +Left ventricular systolic dysfunction 0.8042908455562854 2.5429393171133334 0.0109924318031739 1.0 0.0691982592199805 5 O75844 1 +Poor eye contact 0.5072059757677477 2.542128690028727 0.0110179598403175 1.0 0.069264336895202 43 Q8N183,Q5XKP0,Q86Y39,O43676,Q96CU9,Q9P0J0,Q9Y6M9,Q15907,Q9NPL8,O96000,Q8IUX1,P03886,Q9NX14,Q9UHX1,Q9Y375 15 +Abnormal mitochondrial number 0.7318141980718648 2.540721816188133 0.0110623897696557 1.0 0.0694100000647366 2 P46976 1 +Malrotation of small bowel 0.783914850984995 2.537514869411719 0.0111642625319059 1.0 0.0694100000647366 4 Q8NCH0 1 +Upper airway obstruction 0.7837603100046606 2.536755813283497 0.0111884965325554 1.0 0.0694100000647366 4 Q96HY6,O75844 2 +Abnormal glycosylation 0.586117081249859 2.532061956921007 0.0113393953008276 1.0 0.06989041760392 24 Q9H9E3,Q2TAA5,Q8N511,P46977,Q9Y487,O75787,O60762,P36543,Q9BT22,Q15904,P51571,Q96AA3,Q9H0U3 13 +Abnormality of the optic nerve 0.3840921394619258 2.530941636032368 0.0113756775525482 1.0 0.06989041760392 262 Q8N183,O75665,P04062,Q86Y39,P40855,Q9HC21,Q9Y5U9,Q7LGA3,Q9NZ08,Q96J42,Q96RT7,O96000,P37268,Q8WWY3,O76024,Q9NX14,Q9H061,O43819,Q9Y6M9,Q9UHX1,O43681,P07196,Q10713,Q5XKP0,O43676,O95721,Q9NVI7,O95202,Q3ZCQ8,Q96CU9,Q9P0J0,P00846,Q15907,P07602,Q8N766,Q7KZN9,Q9H490,P49770,Q15043,Q969G3,Q14118,P21964,Q6ZXV5,Q9NZJ7,P51572,Q9UG56,O60313,Q96S66,O43292,P03886,P03915,P00403,Q8NBM4,Q8NAT1,Q15125,Q96L58,Q9H6K4,Q96DA6,P50897,Q9NPL8,O95140,O75381,Q8IUX1,Q8N5K1,Q96HR9,Q9Y375 66 +Abnormal circulating long chain fatty acid concentration 0.8014199783875235 2.529103582223142 0.0114354272892867 1.0 0.06989041760392 5 O75381,P40855,P23786 3 +Retinopathy 0.5519025314955068 2.529084094870168 0.0114360622555025 1.0 0.06989041760392 28 O75306,O95169,P11802,O95202,P00846,Q9NZ08,P52732,O60762,P51648,Q5JRA6,O43819,Q9Y375,Q8NBM4 13 +Abnormal urine magnesium concentration 0.729184925503954 2.527014909694191 0.0115036618943185 1.0 0.070117558212989 2 P05023 1 +Extra axial cerebrospinal fluid accumulation 0.728892784107507 2.5254904645768383 0.0115536916836285 1.0 0.0702539884017252 2 Q03252 1 +Nasogastric tube feeding in infancy 0.8045040310731437 2.524869667738489 0.0115741204786534 1.0 0.0702539884017252 8 Q9UHX1,P07602 2 +Biliary tract neoplasm 0.8004612619450858 2.52447789029212 0.0115870293370901 1.0 0.0702539884017252 5 Q9NZJ7,P07602 2 +Neoplasm of the gallbladder 0.8004612619450858 2.52447789029212 0.0115870293370901 1.0 0.0702539884017252 5 Q9NZJ7,P07602 2 +Elevated systolic blood pressure 0.7248028045574162 2.504117606061204 0.0122757222075815 1.0 0.0735349148789263 2 P42892 1 +Elevated mean arterial pressure 0.7248028045574162 2.504117606061204 0.0122757222075815 1.0 0.0735349148789263 2 P42892 1 +Elevated diastolic blood pressure 0.7248028045574162 2.504117606061204 0.0122757222075815 1.0 0.0735349148789263 2 P42892 1 +Cardiac valve calcification 0.7769657994738535 2.503312268095307 0.0123036934400275 1.0 0.0735349148789263 4 P04062,O75844,O75431 3 +Mitral valve calcification 0.7769657994738535 2.503312268095307 0.0123036934400275 1.0 0.0735349148789263 4 P04062,O75844,O75431 3 +Peroneal muscle atrophy 0.7769657994738476 2.503312268095275 0.0123036934400286 1.0 0.0735349148789263 4 Q9NR77,Q96RL7,Q12768 3 +Abnormal heart rate variability 0.7765992186531989 2.5015039461397555 0.0123667064236807 1.0 0.073815781347566 4 P07602 1 +Abnormality of the temporomandibular joint 0.7754172957614247 2.495670822704664 0.0125719206642971 1.0 0.0747502069949434 4 O75844 1 +Decreased ldl cholesterol concentration 0.7746620991969382 2.4919415018652047 0.012704696000672 1.0 0.0750675693863242 4 Q15800 1 +Small placenta 0.7483927527761788 2.4918840810061447 0.0127067500263309 1.0 0.0750675693863242 3 O75844,P02545 2 +Short umbilical cord 0.7483927527761788 2.4918840810061447 0.0127067500263309 1.0 0.0750675693863242 3 O75844,P02545 2 +Reduced visual acuity 0.4001943460217507 2.4640963643314233 0.0137359176305067 1.0 0.0795616787865262 123 Q8N183,P21912,Q86Y39,O75665,Q9NZ08,O96000,Q8WWY3,Q9NX14,Q9H061,Q9UHX1,Q9Y6M9,O43681,Q10713,O43676,Q96CU9,P00846,P07602,P49770,Q15043,Q969G3,Q96AA3,Q9NZJ7,P53701,O60313,P17900,Q96S66,P03886,Q8NBM4,Q9H6K4,P50897,Q9NPL8,Q8IUX1,Q96HR9,Q9Y375 34 +Fluctuations in consciousness 0.7919561720327083 2.463460071343994 0.0137603221004243 1.0 0.0795616787865262 8 P04062,Q9UJS0,P03886,P03915,O43819,P00403 6 +Abnormal circulating ceruloplasmin concentration 0.7686970229257933 2.4624239446788816 0.0138001437962702 1.0 0.0795616787865262 4 Q8N511 1 +Abnormal urine sodium concentration 0.7166228454572122 2.4611997821112332 0.0138473234346341 1.0 0.0795616787865262 2 Q13423 1 +Testicular adrenal rest tumor 0.7166228454572122 2.4611997821112332 0.0138473234346341 1.0 0.0795616787865262 2 Q13423 1 +Abnormal response to insulin tolerance test 0.7166228454572122 2.4611997821112332 0.0138473234346341 1.0 0.0795616787865262 2 Q13423 1 +Hypernatriuria 0.7166228454572122 2.4611997821112332 0.0138473234346341 1.0 0.0795616787865262 2 Q13423 1 +Leydig cell neoplasia 0.7166228454572122 2.4611997821112332 0.0138473234346341 1.0 0.0795616787865262 2 Q13423 1 +Abnormal circulating citrulline concentration 0.8048839865007491 2.45322070371228 0.0141583440251507 1.0 0.0809449742777846 6 P03915,Q9UJS0,P00846,P03886 4 +Generalized hyperkeratosis 0.7821061952269039 2.4354027627023394 0.0148752220286763 1.0 0.0836935569085963 5 O75844 1 +Abnormality of the cerebrospinal fluid 0.3916724148657199 2.434702687086596 0.0149040301176028 1.0 0.0837533790023342 157 Q8N183,O75665,P04062,Q86Y39,P40855,Q9HC21,Q96J42,O96000,Q9NX14,O43819,Q9Y6M9,P23786,O43681,Q10713,P13073,O43676,P16435,Q8TAA9,O95202,Q96CU9,Q9P0J0,P00846,P07602,Q7KZN9,Q9H490,O60566,Q969G3,Q14118,P21964,Q9NZJ7,Q9NR77,P53701,P03886,Q96I36,P03915,Q6NUK1,P00403,Q8NAT1,Q15125,Q96L58,O95140,Q9NPL8,Q8IUX1,Q15392,Q9Y375 45 +Renal tubular dysfunction 0.487780791592469 2.4331538851556296 0.0149679379963454 1.0 0.0838960442419514 45 Q8N183,P40855,Q86Y39,Q9BRT2,O96000,P50416,Q9NX14,O43819,Q9Y6M9,O43676,Q9Y276,Q96CU9,P35670,P03886,P03915,P00403,Q9NPL8,Q8IUX1,Q9Y375 19 +Concentric hypertrophic cardiomyopathy 0.7627391351738984 2.432833984549074 0.0149811680266385 1.0 0.0838960442419514 4 P00403,P03886 2 +Vitritis 0.7364114552893147 2.4307157148906033 0.0150690328857068 1.0 0.0841673982270752 3 Q9NX14,P53701 2 +Emg neuropathic changes 0.5433375317998946 2.4272389095725604 0.015214233286509 1.0 0.0845683799568561 26 Q9NZJ7,Q9NR77,Q96RL7,O60313,O95140,P07602,O14773,Q969X5,O43819,Q13510,O43681 11 +Decreased light and dark adapted electroretinogram amplitude 0.7354951503341451 2.426018534084995 0.0152654906528399 1.0 0.0846490745226073 3 P50897 1 +Ventricular preexcitation 0.7917241817042302 2.4251716679154844 0.0153011494425858 1.0 0.0846982405945612 7 P13473,P00846,P00403,P03886 4 +Abnormality of coordination 0.3495298972642278 2.412870940997774 0.015827422836032 1.0 0.0871307839271602 339 O14949,Q8N183,Q86Y39,P04062,P05067,Q9NX14,Q9Y6M9,Q5XKP0,O43676,P53007,Q9Y276,O75298,Q5T8D3,P00374,P00846,Q969G3,P11182,O95169,O43924,P00403,Q9Y619,Q9NUN5,O75503,Q9H6K4,P50897,Q2M1P5,Q9UBB4,Q9Y2B2,Q15067,Q96IX5,O96000,O14773,P56589,Q9UID3,O95470,P12694,Q96BR5,Q15907,P07602,Q8N2K0,Q8NI60,P09622,Q96AA3,P12235,P52815,P56556,Q9NZJ7,O00165,O60313,Q9Y487,O60762,P16278,O75027,O43292,P03886,Q9Y3E5,Q8IV08,Q96DA6,Q9NPL8,Q8IUX1,Q8N5K1,P21912,P40855,Q05086,O43819,O43681,Q9NVI7,O95202,Q96CU9,Q9P0J0,Q9Y4P3,Q7KZN9,Q14108,Q13510,Q9NWW5,P35670,Q96RL7,Q8TC12,Q6P4A7,Q96S52,O75381,O75665,Q9NZ08,O75787,O76024,Q01105,Q6DKK2,P07196,Q10713,O95721,Q2TAA5,Q9BUB7,Q9NQZ5,Q9NR77,Q9NQ11,P03915,Q8NBM4,Q9H9E3,O96008,O15118,O95140,Q92643,Q8NBU5,Q9Y375 104 +Blindness 0.4275203250831343 2.408747005137137 0.0160073901773345 1.0 0.0874994708625831 87 Q8N183,P21912,Q86Y39,O75665,Q9NZ08,O96000,Q8WWY3,Q9NX14,Q9Y6M9,O43676,Q96CU9,P00846,P07602,P49770,Q969G3,Q9NZJ7,P53701,P17900,P03886,Q8NBM4,Q9H6K4,P50897,Q9NPL8,Q8IUX1,Q96HR9,Q9Y375 26 +Decerebrate rigidity 0.7756734856967133 2.403952856271494 0.01621886473733 1.0 0.0884455961060553 5 Q9NZJ7,P07602 2 +Clumsiness 0.5682934230292586 2.4025001862427895 0.0162834262692457 1.0 0.0884835238781654 24 Q05086,Q9NP73,Q9NZJ7,P35670,O00165,Q15067,Q9NR77,O75503,P07602,O14773,O43819,Q13510,O43681 13 +Fetal distress 0.5356292418909542 2.401372135881289 0.0163337162726109 1.0 0.0886522551050544 28 Q8N183,Q86Y39,O43676,Q9NVI7,Q96CU9,Q9NPL8,O96000,Q8IUX1,P03886,Q9Y6M9,Q9Y375 11 +Metaphyseal striations 0.7749306487186225 2.4003132591326817 0.0163810465400757 1.0 0.0888045440666696 5 P00813,Q13126 2 +Duplication involving bones of the feet 0.5539098162880564 2.39915314319473 0.0164330403369947 1.0 0.0889817272301667 25 O75665,Q15125,O95202,Q96J42,O75845,O43924,P21964,Q10713 8 +Abnormality of the distal phalanges of the toes 0.7928339456016242 2.395442607670901 0.0166003128522045 1.0 0.0894669492666181 6 O75844,Q7LGA3,O75431 3 +Abnormality of the intrahepatic bile duct 0.7544379513326345 2.3914252440906965 0.0167831013964829 1.0 0.0897175536368835 4 Q9NUN5,Q10713 2 +Diastasis recti 0.7538982507491437 2.3887257494929854 0.0169069177547913 1.0 0.0902746890555832 4 Q8NCH0 1 +Metaphyseal cupping 0.7005550686532398 2.376223934326323 0.0174908442085688 1.0 0.0925347992113586 2 Q14739 1 +Prominent sternum 0.7005550686532326 2.3762239343262856 0.0174908442085706 1.0 0.0925347992113586 2 P16278 1 +Left ventricular hypertrophy 0.5503600829726635 2.372331450892241 0.0176762259084075 1.0 0.0929817910798425 25 O75880,P21912,O75431,O75787,P03886,Q6NUK1,P12235,P00403 8 +Mesoaxial polydactyly 0.7501214285342372 2.369809658881761 0.0177972448562402 1.0 0.0934051301794476 4 O43924,O75665 2 +Paroxysmal involuntary eye movements 0.5637079596029109 2.3688504785043865 0.0178434654514831 1.0 0.0935411704214272 24 Q8N183,Q86Y39,O43676,Q96CU9,Q9NPL8,O96000,Q8IUX1,P03886,Q9Y6M9,Q9Y375 10 +Tongue nodules 0.7495425177184439 2.366906326343197 0.0179374721990879 1.0 0.0939271271515876 4 O43924,O75665 2 +Abnormal placental size 0.748611517100281 2.3622350424741896 0.0181651211588236 1.0 0.0945817833896715 4 O75844,Q6PGP7,P02545 3 +Impaired social interactions 0.4518827496658273 2.3596849219149427 0.0182904623794391 1.0 0.0950196737817986 52 O75746,Q8N183,Q86Y39,Q9NP73,Q15067,O96000,Q9NX14,Q9Y6M9,Q9UHX1,Q5XKP0,O43676,Q2TAA5,P53007,Q96CU9,Q9P0J0,Q15907,P56556,P03886,O43464,Q9NPL8,Q8IUX1,Q9Y375 22 +Capillary hemangioma 0.7630391890947902 2.3580005045195853 0.0183736679864605 1.0 0.095300775442934 9 O75665,Q8N6S5,Q7LGA3,Q9UHX1 4 +Mixed demyelinating and axonal polyneuropathy 0.7849448203093888 2.3573936529344635 0.0184037258772562 1.0 0.095300775442934 6 P00403,P35670,P07196,P03886 4 +Abnormal renal cortex morphology 0.4242700754135571 2.356581345688157 0.0184440275263029 1.0 0.095387293873405 58 P21912,O95470,O75431,P60033,P00813,P00846,Q9NZ08,Q96D53,Q14108,P03886,P03915,P00403 12 +Hypochromic microcytic anemia 0.7217722217547096 2.355344277311094 0.0185055515790741 1.0 0.0954412982518904 3 O75027 1 +Quadriceps muscle weakness 0.7472039928928862 2.3551677393369173 0.0185143461028121 1.0 0.0954412982518904 4 P12235 1 +Concave nasal ridge 0.7213657693103307 2.3532416207176805 0.0186105367077007 1.0 0.0955554469977762 3 Q15125 1 +Hamartoma of tongue 0.7640524266885621 2.3468282376286034 0.0189339808744481 1.0 0.096709781635028 5 O43924,O75665 2 +Abnormality of pulmonary circulation 0.5189162942573592 2.3446038446269943 0.0190473055633793 1.0 0.0969059719645134 32 Q8IZA0,P20674,Q8NBM4,Q9NZ08,O96000,Q14108,P03886,P03915,O75844,Q6NUK1,P00403 11 +Cogwheel rigidity 0.7822776019434587 2.3444898854815213 0.0190531273003145 1.0 0.0969059719645134 6 P00846,P12235 2 +Abnormal protein o linked glycosylation 0.7430575855013339 2.3343127620747515 0.0195793509701571 1.0 0.0976424775654591 4 Q15904,Q9H9E3,Q8N511 3 +Pathologic fracture 0.6647137002302578 2.327433215102578 0.0199422196576541 1.0 0.0991302569390188 16 P35670,Q96L58,Q9Y5U9,O75845,Q13126,Q14108,O15269 7 +Abnormal protein glycosylation 0.6099542086359091 2.325577017013909 0.0200411268431135 1.0 0.0993807050142106 20 Q9H9E3,Q2TAA5,Q8N511,Q9Y487,O75787,O60762,P36543,Q9BT22,Q15904,P51571,Q96AA3,Q9H0U3 12 +Abnormality of epiphysis morphology 0.4217848874077511 2.3252741850890812 0.0200573037463576 1.0 0.0993807050142106 59 Q9Y2B2,O75665,P40855,Q96HY6,Q7LGA3,Q9Y366,P16435,O95202,Q8WVQ1,Q9UG56,Q14739,Q15738,Q9H9E3,Q9Y619,Q15125,Q96L58,O75381,O00116,Q5JRA6,Q2M1P5,Q9Y2U8 21 +Hyperkeratosis 0.4222508690511769 2.324191575441714 0.0201152286337196 1.0 0.099560659016305 61 Q9Y2B2,P21912,O95721,O75431,Q9NWM8,Q96JJ3,P42167,P16615,P51648,P98194,O75844,O15269,Q9Y2U8,P09493 14 +Recurrent pancreatitis 0.7404312765072565 2.321075888861704 0.0202827484274616 1.0 0.1001746031658558 4 P00403,P03886 2 +Aplasia hypoplasia of the phalanges of the toes 0.7142022209234631 2.3160941662417582 0.0205531277645287 1.0 0.1010625375415811 3 Q9Y2B2,P02545 2 +Lacticaciduria 0.7756735013318649 2.3124528651910707 0.0207527399535591 1.0 0.1017325805382987 6 O96000,P03886,P00846,Q9BQT8 4 +Broad chin 0.6882851300029234 2.3107276760335083 0.0208479015418856 1.0 0.1020904679118056 2 P55011 1 +Sensory neuropathy 0.5007434179683324 2.30751911680593 0.021025897768675 1.0 0.1027437294995276 37 Q8IV08,Q96RL7,O60313,P00846,O94905,O95140,Q9NQ11,P03886,P03915,O15269,Q15041,P00403 12 +Enlarged ovaries 0.7365609492994798 2.3015301504989893 0.0213616831811851 1.0 0.1036154064198959 4 P21912 1 +Very long chain fatty acid accumulation 0.773213749382884 2.3004886883952547 0.0214205494087995 1.0 0.1037916842016281 6 O75381,Q5T8D3,P40855 3 +Abnormal nephron morphology 0.4213342006867314 2.2980724403560298 0.0215576665152494 1.0 0.1043463522082664 71 O95169,P21912,O95470,Q9Y276,O75431,P60033,Q8NBM4,P00813,P00846,Q9NZ08,Q9Y4P3,Q96D53,Q14108,P03886,P03915,O43819,P23786,P00403 18 +Abnormal vascular physiology 0.4282362492082571 2.2971230111577436 0.0216117534207187 1.0 0.1044983838013347 56 P04062,Q8IZA0,P20674,Q9NWM8,Q8NBM4,Q9Y4P3,Q9NZ08,O96000,Q14739,Q14108,P03886,P03915,O75844,Q6NUK1,P00403 15 +Aplasia involving bones of the lower limbs 0.6853637160385673 2.295055556088912 0.0217299406556399 1.0 0.1048498078965328 2 P02545 1 +Macrovesicular hepatic steatosis 0.7717331336879057 2.2932786935789156 0.021831965082439 1.0 0.1052318986400407 6 Q5XKP0,P23786,O75431 3 +Abnormality of krebs cycle metabolism 0.7710572504031565 2.2899853390945677 0.0220221665458262 1.0 0.1057063994199658 6 P00846,P03886 2 +Nemaline bodies 0.7319803184791419 2.2783373102973656 0.0227064883308161 1.0 0.1083141803606632 4 O43676 1 +Foot acroosteolysis 0.7488622131519369 2.2715564585898 0.0231133132735412 1.0 0.1091478659291851 5 O75844 1 +Osteolysis involving bones of the feet 0.7488622131519369 2.2715564585898 0.0231133132735412 1.0 0.1091478659291851 5 O75844 1 +Nonprogressive cerebellar ataxia 0.7306037506841433 2.2713546956462323 0.0231255146271431 1.0 0.1091478659291851 4 O75027 1 +Central scotoma 0.7383117149868353 2.270868897092685 0.0231549156166812 1.0 0.1091478659291851 10 Q9H6K4,O60313,P00846,P03915,P03886,Q9H061 6 +Morphological abnormality of the pyramidal tract 0.5504065320903475 2.2704969769703194 0.0231774465071519 1.0 0.1091478659291851 24 Q13045,Q9Y619,O75298,P00846,Q9Y4P3,P11166,Q9H9P8,O00400,Q8NFV4,Q12768,Q9UBB4 11 +Incoordination 0.4178562883009231 2.257264352643104 0.0239915614071017 1.0 0.1121228346490112 72 P21912,P04062,Q05086,O75787,O14773,Q01105,O43819,Q6DKK2,O43681,Q10713,P53007,P00846,P07602,Q13510,P12235,Q9NZJ7,P35670,O00165,Q9NR77,Q8TC12,Q9Y619,Q9NUN5,O75503,O95140,Q9UBB4 25 +Abnormal cellular phenotype 0.3818799329346366 2.2548494825765553 0.0241427781204004 1.0 0.1126011352012198 196 Q8N183,P21912,P04062,Q86Y39,O96000,O75787,O14773,Q9NX14,Q9Y2R0,P14174,Q9Y584,Q9Y6M9,P23786,P13073,O43676,Q9BUB7,Q3ZCQ8,Q96CU9,P00813,Q9UJS0,P09601,P00846,P07602,Q9P0J0,Q7KZN9,O60566,Q14108,Q969G3,P21964,Q13510,Q9NWW5,P12235,Q9NZJ7,P20674,Q96DF8,P60033,Q70HW3,Q9HA77,Q14739,P03886,P03915,O75844,Q9UBX3,P00403,O75880,Q9NPL8,Q92643,Q8IUX1,Q8N5K1,Q9Y375,Q9H0U3 51 +Abnormality of hepatobiliary system physiology 0.4152840399528542 2.250210418229383 0.0244355912689318 1.0 0.1137365702699371 85 P04062,P28288,P40855,Q96A33,O75787,P50416,P56589,Q9BT22,O43819,P23786,Q9UID3,Q10713,Q5XKP0,Q9Y276,Q9NWS8,P22695,P00846,Q01130,P22830,Q13510,O95169,P35670,Q8N511,O75845,P03886,P03915,P08574,Q9H9E3,Q9Y619,O15118,O75381 31 +Supernumerary tooth 0.7473895111680232 2.241577843868395 0.0249886692596414 1.0 0.1154942707607101 8 Q9Y2B2,Q9UHX1 2 +Abnormal electroretinogram 0.4986675528293823 2.240811472534012 0.0250382894999308 1.0 0.1154965424945948 35 O75665,P00846,P50897,Q53H12,O14773,Q96S66,O43924,Q96HR9,P12235 9 +Cognitive impairment 0.3807964502539244 2.23497824743863 0.0254187768548046 1.0 0.1165469888029251 180 P21912,P04062,P54802,P40855,P27544,Q9NZ08,P05067,Q9BQE5,O76024,Q9Y2R0,O43819,Q6DKK2,O43681,P07196,Q10713,Q5XKP0,O95470,Q9NQZ5,Q9UJS0,P00846,P07602,P49770,Q14108,Q969G3,P21964,Q13510,Q9NWW5,P12235,O95169,Q9NZJ7,P35670,Q96RL7,O60313,P17900,Q9NR50,Q9NQ11,P03886,P13473,P03915,Q8N6S5,P00403,Q8NBM4,Q9Y619,O96008,O75503,Q9H6K4,O15118,P50897,Q9NPL8,O95140,O75381,Q8N5K1,Q9UBB4 53 +Decreased activity of mitochondrial complex iv 0.6315092432991121 2.23311770859951 0.0255411831086334 1.0 0.1165790551674896 17 P13073,Q9Y2R0,Q9Y584,P20674 4 +Optic atrophy 0.3802844975717263 2.2330262664710663 0.0255472122806712 1.0 0.1165790551674896 201 Q8N183,O75665,Q86Y39,P40855,Q9NP73,Q15067,Q9HC21,Q9Y5U9,Q96TA2,Q96J42,Q96RT7,P56589,Q8WWY3,O76024,Q9BPX6,Q9NP72,Q9H061,Q9NRG9,O43819,O43681,Q5XKP0,O95721,Q9NVI7,O95202,Q3ZCQ8,Q96CU9,Q9P0J0,P00846,Q15907,P07602,Q8N766,Q8N2K0,Q7KZN9,Q9H9P8,Q15043,Q9H490,Q14118,P49770,P21964,Q9H2M9,Q6ZXV5,P56556,O95169,O75306,Q9NZJ7,O43505,Q6PJG6,P51572,O60313,P10644,O60762,Q9NR50,P16278,Q96F07,O43292,P03886,P03915,Q12768,P00403,Q8NAT1,Q15125,Q9H6K4,Q96DA6,P50897,P52732,O95140,Q9UI09,O75381,Q2M1P5,Q8N5K1,Q96HR9 71 +Peripheral demyelination 0.5960710345476515 2.2329573521200508 0.0255517569132421 1.0 0.1165790551674896 20 Q9NZJ7,Q9NR77,P00846,P07602,P03886,P03915,P07196,O43681 8 +Gastrointestinal stroma tumor 0.7229991881475898 2.232674584369134 0.0255704116664849 1.0 0.1165790551674896 4 P60033 1 +Widened cerebral subarachnoid space 0.7228318746700012 2.2318215330387754 0.0256267605705891 1.0 0.1165790551674896 4 P00403,P03886 2 +Lower limb pain 0.7588289950772882 2.2301757078175126 0.0257357802995787 1.0 0.1169531317756006 6 P00846,O75477 2 +Impaired proprioception 0.472831419860282 2.227019873181333 0.025945945632678 1.0 0.1176760998773429 43 Q9Y619,O75298,O00165,Q9NR77,Q96RL7,Q8IV08,Q9H6K4,P00846,O94905,O95140,O14773,Q9NQ11,O00400,O43819,P07196 15 +Progressive gait ataxia 0.6978924944823187 2.2249539574866497 0.0260843292023453 1.0 0.1179799723604502 13 Q05086,Q9NZJ7,P00846,P07602,O14773,O43681 6 +Peripheral hypermyelination 0.6967284950444617 2.2247723645650774 0.0260965234958576 1.0 0.1179799723604502 3 P07196 1 +Central apnea 0.7426916326527198 2.2178419749181075 0.0265656090013184 1.0 0.1195822385402971 8 Q8N5K1,Q9NZJ7,O76024,P07602 4 +Focal segmental glomerulosclerosis 0.529174196910956 2.2105172617587674 0.0270692838681025 1.0 0.1211021942371036 25 O95470,O75431,Q96D53,Q14108,P03886,P00403 6 +Difficulty in tongue movements 0.6937763197289959 2.20924384462783 0.0271576847636718 1.0 0.121122478502035 3 Q9NQ11 1 +Stroke like episode 0.7475181368038647 2.2073337027403457 0.0272907543753835 1.0 0.1212688487577312 7 Q96AA3,O76024,P00403,P03886 4 +Nephrotic syndrome 0.5068381407704962 2.205643122461662 0.0274089972371252 1.0 0.1216769357116309 30 O95470,P00813,Q96D53,Q8NCH0,Q14108,Q9BT22 6 +Agenesis of cerebellar vermis 0.6925127310193109 2.2025885032364867 0.0276237649659383 1.0 0.1219506265040161 3 O43924 1 +Abnormal epiphyseal ossification 0.6249540868955324 2.192112694530852 0.0283713703450498 1.0 0.1245097852857046 17 Q96HY6,P40855,Q15125,Q96L58,Q9UG56,O75381,O00116,Q14739,Q2M1P5,Q15738 10 +Episodic vomiting 0.6918225691588392 2.1913191842873148 0.0284287027397676 1.0 0.1246426852757841 13 Q2TAA5,P22695,P00846,P03886,P03915,P00403 6 +Limb pain 0.7217287490720907 2.1844884226597645 0.0289263770867647 1.0 0.1265838040036199 10 O15269,P00846,O75477 3 +Acanthocytosis 0.7127863089027144 2.1804441996705455 0.0292245508252277 1.0 0.1277672962074474 4 Q96RL7 1 +Increased c peptide level 0.6634531113058757 2.1765560743709114 0.0295137055647496 1.0 0.1285436249927848 2 Q16836 1 +Depletion of mitochondrial dna in muscle tissue 0.7113746606433403 2.1731992128962374 0.029765327007772 1.0 0.1293949309922768 4 P12235 1 +Neurofibrillary tangles 0.7101561030926286 2.1669402239538713 0.0302394123491827 1.0 0.1312902515560622 4 O15118,O96008 2 +Multiple lipomas 0.7318752953980844 2.1629396029808734 0.0305458252565746 1.0 0.1317932235789289 8 P03915,Q9Y2U8,Q8TAA9 3 +Laryngeal dystonia 0.6832261835184272 2.153513545953425 0.0312783406630883 1.0 0.1341998079846471 3 Q96RL7,O75569 2 +Slow pupillary light response 0.7060115684267821 2.1456175906683175 0.0319035008429637 1.0 0.1357445354426381 4 Q9NZJ7,P07602 2 +Abnormal pupillary light reflex 0.706011568426782 2.1456175906683175 0.0319035008429637 1.0 0.1357445354426381 4 Q9NZJ7,P07602 2 +Abnormal csf protein level 0.6833040630842016 2.143895074607467 0.0320412949449238 1.0 0.1359542238547043 13 Q9NZJ7,Q9NR77,P07602,P03886,O43681,P00403 6 +Hallucinations 0.4420762958466807 2.136669182881337 0.0326249082239 1.0 0.1381760818894591 49 P04062,P05067,Q9BQE5,O76024,Q6DKK2,O43681,Q9Y276,Q9UJS0,P07602,P11182,P21964,Q9NWW5,Q9NZJ7,O60313,Q9NQ11,O96008,O75503,P50897,Q8N5K1,P50336 20 +Disproportionate short stature 0.5061081135095977 2.133800065567003 0.0328591505411532 1.0 0.1389128125629673 26 Q96HY6,Q15125,Q7LGA3,Q8WVQ1,O00116,Q14739,Q15392,Q9UHX1 8 +Vascular skin abnormality 0.3711527446693681 2.1319544875091103 0.0330105882277267 1.0 0.1394251059150914 128 Q9Y2B2,P21912,P04062,P49257,P00846,P51648,Q14108,P22830,P21964,Q8IZA0,P35670,P60033,P53701,Q8NCH0,Q14739,Q13126,P03886,P03915,O75844,Q8N6S5,Q6NUK1,P00403,Q9H9E3,Q15125,Q96L58,Q9NWM8,P98194,Q96JJ3 28 +Microcytic anemia 0.7187235909226709 2.131138575672261 0.0330777275396778 1.0 0.1395137698722418 9 P22830,O75027,Q9UBX3,Q9BQT8 4 +Myoclonus 0.3976179753254316 2.1309636935184924 0.0330921333486025 1.0 0.1395137698722418 102 Q9Y2B2,P04062,Q05086,P27544,P05067,O14773,Q01105,Q10713,P13073,P00374,Q96CU9,P00846,Q9NQZ5,P07602,Q14108,Q969G3,Q13510,Q96AA3,Q9NWW5,Q9NZJ7,O75845,Q9NQ11,Q9HA77,P03886,P03915,Q9UBX3,P00403,O96008,P50897,Q9NPL8,Q8NBU5 31 +Abnormal retinal artery morphology 0.5314802416184558 2.1286322203692456 0.0332847005862457 1.0 0.1400015218684701 24 Q9NZJ7,P00846,Q9Y4P3,P07602,P17900,Q13510,P03886,P03915,P21964 9 +Impaired vibratory sensation 0.4881860068168952 2.1284598785384334 0.0332989730832993 1.0 0.1400015218684701 34 O75298,O00165,Q9NR77,Q96RL7,P00846,O94905,O95140,O14773,Q9NQ11,O00400,O43819,P07196 12 +Leukodystrophy 0.406211805357081 2.127466272724915 0.0333813607647672 1.0 0.1402199730210096 66 P21912,Q86Y39,O43676,Q9NZJ7,Q96CU9,Q9P0J0,Q9NPL8,P07602,O96000,Q7KZN9,Q8IUX1,P03886,O43819,Q9Y6M9,O43681 15 +Patchy changes of bone mineral density 0.677928160402373 2.1253877397880703 0.0335542724509825 1.0 0.1408179302860906 3 Q13126 1 +Abnormality of corneal size 0.4517653484350176 2.12440420607952 0.033636358596627 1.0 0.1410339767181596 46 Q8NAT1,Q15125,O95202,Q9NWM8,Q9Y4P3,Q96J42,Q8NCH0,O75845,Q14118 9 +Segmental peripheral demyelination remyelination 0.7306149096232812 2.122524426067679 0.0337937237381511 1.0 0.1414364023482293 7 Q9NR77,P00846,P07196,P03886 4 +Hand polydactyly 0.4820911338627839 2.120259484393146 0.0339841684200203 1.0 0.1421043993461469 36 O75665,Q9UM00,Q15125,O95202,Q96J42,O75845,O43924,P21964,Q9UHX1,Q10713 10 +Hyperactive patellar reflex 0.7161589644333823 2.1178234135071174 0.0341900256575795 1.0 0.1427061940490277 9 P13073,P21912,Q15041 3 +Cytochrome c oxidase negative muscle fibers 0.7287965075411986 2.113350755751239 0.0345707574899656 1.0 0.1437744138210845 7 Q9Y2R0 1 +Abnormality of the antitragus 0.6753360607831693 2.11159300262639 0.0347213732580686 1.0 0.1438813740766011 3 Q92643,Q9H2M9 2 +Cardiorespiratory arrest 0.6743241817380186 2.1062018895827395 0.0351868191005728 1.0 0.1454178138255065 3 P13473 1 +Prominent ear helix 0.6980537716999603 2.1045263548801407 0.0353325581404115 1.0 0.1456075684172325 4 Q5T8D3,O75844 2 +Ketotic hypoglycemia 0.6738749269433181 2.1038072494088413 0.0353952641816319 1.0 0.1456262297758572 3 Q9NNW7,Q13423 2 +Hepatic failure 0.427012650859326 2.1012023028909756 0.0356232113469439 1.0 0.1464333255010861 52 P04062,P40855,P28288,P50416,P56589,P23786,Q10713,P00846,P09622,P22830,Q13510,P35670,O75845,P03886,P03915,P08574,Q9H9E3,Q9Y619,O15118,O75381 20 +Vocal cord paresis 0.6970555802429357 2.099358099450159 0.0357853453857071 1.0 0.1467071810830412 4 O95140 1 +Abnormal left ventricle morphology 0.4954177578215764 2.093945273183459 0.0362648556483495 1.0 0.1481457932868748 29 O75880,P21912,O75431,O75787,O60566,P03886,Q6NUK1,P12235,P00403 9 +Delayed epiphyseal ossification 0.7129292654771897 2.0907596119363916 0.0365496182518918 1.0 0.1489130335143391 5 Q96HY6,Q9UG56,Q96L58 3 +Postaxial polydactyly 0.4986649001186451 2.088618524022278 0.0367420763465522 1.0 0.1495649185555766 27 O75665,Q9UM00,Q15125,Q9BRT2,Q9Y366,Q96J42,O75845,Q14739,O43924,Q10713 10 +Abnormal circulating cholesterol concentration 0.4858137347586473 2.0872474951344047 0.0368657682141422 1.0 0.1499359752257434 33 Q9H9E3,Q9NZJ7,Q9NVI7,O75431,Q15125,Q8N511,Q9UJS0,P07602,O75845,P37268,P50402,Q14739,Q15800,Q15392,Q15738 15 +Glucose intolerance 0.379693957819795 2.0815710145920012 0.0373816712660854 1.0 0.151612197584185 118 Q8N183,O75665,Q86Y39,Q9Y375,Q9Y5U9,O96000,Q8WWY3,O76024,Q9NX14,Q9Y6M9,O43676,Q8TAA9,Q96CU9,P00846,Q9Y4P3,P12235,O60313,P03886,P03915,O75844,P00403,O75431,Q9NPL8,Q8IUX1,Q5JRA6,Q8N5K1,Q96HR9,Q96JJ3,Q9Y2U8 29 +Microcornea 0.4851151804642621 2.08126649521996 0.0374095201070352 1.0 0.151612197584185 33 Q8NAT1,Q15125,Q9NWM8,Q8NCH0,Q96J42,O75845,Q14118 7 +Decreased circulating aldosterone level 0.6924875767319629 2.0756670583253025 0.0379247546554004 1.0 0.1532806725251732 4 Q9NRG9,Q9NNW7,Q13423 3 +Emg chronic denervation signs 0.65513615819083 2.073500199863805 0.038125752535383 1.0 0.1532806725251732 14 Q9NZJ7,O60313,P07602,Q969X5,O43819,Q13510,O43681 7 +Dysmenorrhea 0.6444639205375479 2.072483472221192 0.0382203760267836 1.0 0.1532806725251732 2 P02545 1 +Pituitary prolactin cell adenoma 0.644463920537546 2.072483472221185 0.0382203760267843 1.0 0.1532806725251732 2 P10644 1 +Elevated circulating growth hormone concentration 0.644463920537546 2.072483472221185 0.0382203760267843 1.0 0.1532806725251732 2 P10644 1 +Broad jaw 0.6444639205375454 2.07248347222118 0.0382203760267847 1.0 0.1532806725251732 2 Q8TAD8 1 +Action tremor 0.400601965088833 2.0699471766599733 0.0384572913814549 1.0 0.1540966945093428 63 O75787,O14773,O43681,Q9BUB7,Q5T8D3,P00846,P07602,Q14108,Q9NZJ7,Q9NR77,Q96RL7,Q9NQ11,Q9HA77,O75027,P03886,P03915,Q9H6K4,Q96DA6,O95140 19 +Postural tremor 0.5354519641505987 2.0648481548310165 0.0389373698862745 1.0 0.155749479545098 23 Q9NR77,Q9H6K4,P00846,O95140,Q9NQ11,O14773,Q14108,P03886,P03915 9 +Respiratory distress 0.4067864075227608 2.0603689557771423 0.0393632823617315 1.0 0.156938810524495 56 O95169,P53007,P04062,Q9NZJ7,Q96L58,P53701,P00846,Q9Y366,P07602,Q969X5,P51571,P23786,P03886,Q9NX14,P03915,O43819,Q13510,Q9UHX1 18 +Muscle stiffness 0.5921135398702377 2.0533793550073094 0.0400357999719853 1.0 0.1590410139636884 18 Q9NZJ7,P52732,P00846,P07602,P11166,Q9NQ11,Q15392,Q8NBU5,P23786 9 +Axonal degeneration regeneration 0.6878740550140134 2.0516739176121757 0.0402013631949746 1.0 0.1592845069668472 4 O95140,Q8TB36 2 +Mandibular aplasia 0.7042919592603476 2.046725253361257 0.0406850682894401 1.0 0.160780231528019 5 Q9NX14,P53701 2 +Hypermagnesemia 0.6397896581945718 2.046669951716331 0.0406905014757716 1.0 0.160780231528019 2 P29992 1 +Hypocalciuria 0.6397896581945718 2.046669951716331 0.0406905014757716 1.0 0.160780231528019 2 P29992 1 +External ophthalmoplegia 0.6182564718160617 2.045218647199025 0.0408333068932598 1.0 0.160780231528019 16 P21912,O60313,P03886,P03915,P12235,P00403 6 +Abnormal enchondral ossification 0.4853250216405218 2.0446710139885695 0.0408873031511531 1.0 0.160780231528019 31 Q96HY6,P40855,Q9Y619,Q15125,O95202,Q96L58,Q9UG56,Q8WVQ1,O75381,O00116,Q14739,Q2M1P5,Q15738 13 +Macrodontia of permanent maxillary central incisor 0.6392053754017 2.043437835083782 0.0410091153120306 1.0 0.1609625241548869 2 P21281 1 +Broad hallux phalanx 0.6392053754017001 2.043437835083782 0.0410091153120306 1.0 0.1609625241548869 2 Q6DKJ4 1 +Abnormality of the phalanges of the hallux 0.6860364028729764 2.0420985365731505 0.0411417580336896 1.0 0.1613457200163762 4 Q8WVQ1 1 +Short upper lip 0.6852308087854482 2.037897545381732 0.0415601801384533 1.0 0.1627096942039021 4 O95202 1 +Epidermoid cyst 0.6377446684195209 2.035352271511543 0.0418154401101011 1.0 0.1632758201704436 2 O60716 1 +Abnormality of chromosome segregation 0.6841071173364706 2.0320343756697845 0.0421501760215567 1.0 0.1638928310858833 4 O60566,Q14739 2 +Abnormal circulating non proteinogenic amino acid concentration 0.6995692323682458 2.031198948318619 0.0422348170398902 1.0 0.1638928310858833 9 Q9UJS0,P00846,P05067,P03886,P03915 5 +Scotoma 0.663212505533405 2.0310176004067415 0.0422532092202141 1.0 0.1638928310858833 13 Q9H6K4,O60313,P00846,P03915,P03886,Q9H061 6 +Distal sensory impairment of all modalities 0.7011777389324811 2.0307938068275133 0.0422759155509142 1.0 0.1638928310858833 5 O15269 1 +Hypoplastic heart 0.6600954774214609 2.030034084428617 0.0423530747979179 1.0 0.1639949362232053 3 Q12768 1 +Upper limb postural tremor 0.6834258988599962 2.02847801839499 0.0425114845498513 1.0 0.1642019453526529 4 Q9NR77,P20700,Q9HA77 3 +Progressive external ophthalmoplegia 0.6916598591854175 2.0256234828360777 0.042803383231841 1.0 0.1650527112404382 10 O60313,P00403,P12235,P03886 4 +Horizontal nystagmus 0.4917830381604 2.0182781124707376 0.0435623049147673 1.0 0.1672792508727064 26 P04062,Q9NZJ7,P00846,O60313,P07602,O14773,Q9NQ11,Q9H061 8 +Abnormal tissue metabolite concentration 0.6131595262976471 2.0137013479965997 0.0440408984206051 1.0 0.1686953116559836 16 P40855,Q9NZJ7,Q9Y276,Q5T8D3,P07602,O75381,P17900,O43681 8 +Increased serum pyruvate 0.467332745784134 2.0127595524026307 0.0441399309718826 1.0 0.1689342208624876 37 Q8N183,P21912,Q86Y39,O43676,P22695,Q96CU9,Q9NPL8,Q70HW3,O96000,Q8IUX1,Q9BWD1,P03886,Q9NX14,Q9Y6M9,Q9Y375 15 +Abnormality of the gallbladder 0.4589812967932464 2.0116522397810885 0.0442566084832549 1.0 0.1692402090380405 40 P40855,Q9NZJ7,O95202,Q96A33,Q9Y4P3,P07602,P22830,P21964,O43681 9 +Angiokeratoma 0.6560490940970216 2.0082508691652663 0.0446166398792569 1.0 0.1703342805000959 3 P16278,P06280 2 +Choroid plexus cyst 0.6554646405610873 2.0051000615264027 0.044952350915917 1.0 0.1713320372378378 3 Q8IYI6,O43175 2 +Abnormal muscle fiber morphology 0.3964547009847467 2.002576903628954 0.0452227209845157 1.0 0.1717163519024718 72 P53007,O43676,Q9Y276,O96008,Q96RL7,P00846,P12235,O60313,P05067,Q70HW3,Q9H2D1,P50402,Q14118,P03886,P03915,P23786,P07196,P00403 18 +Abnormal peripheral myelination 0.4707855040049896 1.9985053177650465 0.0456619039934174 1.0 0.1725467632852534 35 Q9NZJ7,Q9NR77,Q96RL7,P00846,O95140,P07602,P03886,P03915,O15269,P07196,O43681 11 +Nephropathy 0.5378138865799941 1.994257546374864 0.0461239161604813 1.0 0.1730750705594826 22 Q10713,Q14108,O76024,P03886,Q8N5K1,P00403 6 +Peripheral axonal degeneration 0.3956462612742623 1.991465912800799 0.0464296891277384 1.0 0.1736590969972556 76 Q9BQT8,Q9HC21,O76024,O15269,Q6DKK2,P07196,Q9NVI7,P00846,P07602,P12235,Q9NZJ7,Q96RL7,O60313,Q9NQ11,P03886,P03915,P00403,Q8IV08,O95140 19 +Abnormal retinal vascular morphology 0.4044815200978276 1.9882698176121905 0.0467818569876392 1.0 0.1746927042131618 55 O75665,P21912,Q96HR9,Q9NZJ7,Q96DF8,P21964,P00846,Q9Y4P3,P07602,P17900,Q96S66,Q8WWY3,P03886,Q02978,P03915,Q13510 16 +Retrocollis 0.6502045587375747 1.976692072346864 0.0480764474608319 1.0 0.1788024777235784 3 Q99720,O75569 2 +Moderate albuminuria 0.6721705757611538 1.9695101256928744 0.048894540965316 1.0 0.1805336897180902 4 Q9Y5U9 1 +Functional motor deficit 0.3618656188505182 1.9677049871346557 0.0491019916844985 1.0 0.1808648902335487 155 P21912,P04062,Q05086,Q9HC21,O75787,O14773,Q9NX14,Q9Y2R0,O43819,P23786,O43681,P07196,P53007,Q9Y276,O75298,P00846,Q15907,P07602,Q14118,Q13510,P12235,Q9NZJ7,P35670,O75477,Q9NR77,Q96RL7,P53701,Q53H12,Q9NQ11,O43292,P03886,P13473,P03915,Q15041,P00403,Q9NWM8,O95140,Q9H2D1,Q8IUX1 39 +Posterior embryotoxon 0.5676415205320653 1.963968401183018 0.049533756480423 1.0 0.182063211081021 19 P40855,Q96DF8,P53701,Q7LGA3,Q9Y4P3,O75381,Q9NX14,P21964 8 +Duplication of hand bones 0.3908507000556007 1.9631833931511156 0.0496248682981255 1.0 0.182063211081021 61 O75665,Q9UM00,Q15125,O95202,Q96J42,Q8WVQ1,O75845,O43924,P21964,Q9UHX1,Q9Y2U8,Q10713 12 +Impaired vibration sensation in the lower limbs 0.6202770952141448 1.9600777269086376 0.049986706120549 1.0 0.1832448224371438 15 O75298,Q9NR77,P00846,O00400,O43819 5 +Furrowed tongue 0.7043137340173898 1.958320177884554 0.0501924545616085 1.0 0.1837067757107962 6 Q96J42 1 +Emg axonal abnormality 0.645562102355246 1.9515439883515036 0.0509923688066999 1.0 0.1855481575382412 3 Q9NQ11 1 +Cold induced muscle cramps 0.6450300757008052 1.9486574897109592 0.0513363416387846 1.0 0.1861647809764849 3 P23786 1 +Visual field defect 0.427005400910499 1.9470992032909504 0.0515228425176483 1.0 0.186648787988462 48 P40855,Q9H6K4,O60313,P00846,P03915,O95140,O75381,Q8WWY3,Q8TC12,P03886,Q9H061,P00403 12 +Ventricular arrhythmia 0.4518470476771241 1.9454822913158736 0.0517169590256403 1.0 0.1872048289003539 40 P21912,Q9HD47,P09493,P13473,P00846,P50402,P42892,P03886,P03915,P23786,P12235,P00403 12 +Atrophic scars 0.6829239502092963 1.94342875344562 0.0519643759512995 1.0 0.187656664601732 9 Q9NWM8,Q8NCH0 2 +Abnormality of retinal pigmentation 0.3913613262612975 1.9414780755787608 0.0522003162186244 1.0 0.1882152246756035 80 Q8N183,P21912,P40855,O75665,Q96RT7,Q8WWY3,O76024,Q96CU9,Q9P0J0,P00846,Q7KZN9,P51648,P53701,Q9UG56,Q96S66,P03886,P03915,P00403,O75381,Q96HR9,Q96JJ3 21 +Falls 0.6756529526161691 1.9398795147411796 0.0523943342065134 1.0 0.1886196031434482 10 P21912,Q9BQT8,Q96RL7,O75787,Q9NQ11 5 +Osteoarthritis 0.6613628373241021 1.9376635438999932 0.0526642844287315 1.0 0.1892956494911035 12 Q96HY6,P35670,Q8WVQ1,Q14108,O75844 5 +Abnormal retinal morphology 0.3602937322991446 1.9359688197004783 0.0528715199246336 1.0 0.1897255798255294 226 Q8N183,Q9Y2B2,P04062,P21912,P40855,O75665,Q7LGA3,Q9NZ08,Q96J42,Q96RT7,O14773,Q8WWY3,O76024,Q9NX14,O43819,Q9UHX1,Q10713,Q5XKP0,Q9Y276,O95202,Q5T8D3,Q96CU9,Q9P0J0,P00846,Q9Y4P3,P07602,Q7KZN9,P51648,Q14118,P21964,Q13510,Q9NWW5,O95169,Q9NZJ7,Q96DF8,P53701,Q9UG56,O60313,Q8NCH0,P17900,Q96S66,Q8TC12,P03886,O43924,Q02978,P03915,P10619,Q8N6S5,P00403,Q9UM00,Q8NBM4,Q9Y619,Q8NAT1,P50897,O75381,Q5JRA6,Q96HR9,Q96JJ3,Q9Y375 59 +Abnormal full field electroretinogram 0.6877673490966478 1.935396786829103 0.0529416233168902 1.0 0.1897255798255294 8 P00846 1 +Abnormal light and dark adapted electroretinogram 0.6877673490966478 1.935396786829103 0.0529416233168902 1.0 0.1897255798255294 8 P00846 1 +Abnormal circulating proteinogenic amino acid derivative concentration 0.4776778777725355 1.9310319374092748 0.0534791029706778 1.0 0.1908714802902566 28 O75880,Q5XKP0,Q9NUN5,P20674,Q9BUB7,P22695,Q9P0J0,Q9UJS0,P00846,O96000,Q8IUX1,P03886,P03915 13 +Abnormal auditory evoked potentials 0.6805518339845148 1.9308512410348668 0.0535014514677525 1.0 0.1908714802902566 9 P07602,O60313,Q9NZJ7,Q15125 4 +3 methylglutaconic aciduria 0.6597924743444877 1.9289339533687293 0.0537390620533462 1.0 0.1910877256183643 12 Q5XKP0,Q9NVI7,Q9BUB7,Q9H6K4,Q96DA6,Q53H12 6 +Decreased number of large peripheral myelinated nerve fibers 0.6812736896183176 1.9282890520300824 0.0538191828033747 1.0 0.1911552382158464 5 O15269,P07196 2 +Ascending tubular aorta aneurysm 0.6810673246660119 1.927220138548994 0.0539522012560014 1.0 0.1911552382158464 5 O75844 1 +Scaphocephaly 0.6965049159131561 1.9186838354379685 0.0550243584510978 1.0 0.1934036946931037 6 O75665,P40855 2 +Distal peripheral sensory neuropathy 0.6953525554180693 1.9128200222217016 0.0557710970107441 1.0 0.1948394351975048 6 P00403,P03886 2 +Hepatomegaly 0.3612919756977423 1.9115763228621303 0.0559305586623877 1.0 0.1952484956941535 183 Q8N183,Q96HY6,Q86Y39,P04062,P28288,P54802,P40855,Q15067,Q9HC21,Q96A33,O96000,O95235,P56589,P50416,O75787,Q9BT22,Q9NX14,P14174,Q9Y6M9,P23786,Q10713,P53007,O43676,Q9NWS8,Q9NVI7,Q9BUB7,P00374,P00813,Q9UJS0,P09601,P00846,Q01130,P07602,Q96CU9,Q14108,P09622,Q13510,Q96AA3,P56556,Q9NZJ7,P20674,P35670,P60033,Q96RL7,O75845,O60762,P16278,Q6PGP7,Q14739,P03886,Q9Y3E5,Q96I36,P03915,O75880,Q9H9E3,Q9Y619,P14927,O75431,O15118,Q96S52,Q9NPL8,O95140,O75381,Q8IUX1,Q15904,Q9Y375,Q9H0U3 67 +Abnormal gallbladder morphology 0.4631036964906766 1.9102001356554532 0.056107449712123 1.0 0.1955696885578387 34 P40855,Q9NZJ7,Q96A33,Q9Y4P3,P07602,P22830,P21964,O43681 8 +Arthritis 0.4331744933554502 1.9091773051691676 0.0562392229180483 1.0 0.1958808308438148 45 Q96HY6,P04062,P35670,P21964,Q96RL7,Q9NZ08,Q8WVQ1,P10321,Q14739,Q14108,O75844,Q13510,Q9Y2U8,Q8NBM4 14 +Aplasia hypoplasia of toe 0.4672396430623016 1.9083015967697932 0.0563522467551271 1.0 0.1961262485253973 32 P13073,O75665,O95202,P00813,Q7LGA3,Q9NX62,Q13510,Q9UHX1 8 +Ventricular hypertrophy 0.4530371369709628 1.9068349584180464 0.0565419628547965 1.0 0.196341646446799 38 O75880,P21912,O75431,O75787,P03886,O75844,P23786,Q6NUK1,P12235,P00403 10 +Non midline cleft palate 0.613496932515345 1.900036729940109 0.0574282996702979 1.0 0.1988034619609554 2 O60716 1 +Bilateral cleft palate 0.613496932515345 1.900036729940109 0.0574282996702979 1.0 0.1988034619609554 2 O60716 1 +Bilateral cleft lip and palate 0.613496932515345 1.900036729940109 0.0574282996702979 1.0 0.1988034619609554 2 O60716 1 +Axonal degeneration 0.692785638643308 1.8997447416667217 0.0574666257230886 1.0 0.1988034619609554 6 Q6DKK2,Q9BQT8 2 +Hyperkeratotic papule 0.6353009935710043 1.895709251029894 0.0579985013642152 1.0 0.2000530646500991 3 Q9H488,Q07954 2 +Spastic paraparetic gait 0.6749902926973206 1.8956866157986472 0.0580014961745947 1.0 0.2000530646500991 5 O75787,Q15041 2 +Decreased circulating level of specific antibody 0.6794584534960193 1.891879696613018 0.058507011530746 1.0 0.2014949993525243 8 P60033,P00813 2 +Glomerular sclerosis 0.4584031702614957 1.888858016247433 0.0589108563881202 1.0 0.2027342989069887 35 P21912,O95470,O75431,Q96D53,P03886,P00403 6 +Exercise intolerance 0.45782603948723 1.883716994359719 0.0596032664379226 1.0 0.2046586078583813 35 P13473,Q53H12,Q9H2D1,Q8IUX1,P03886,P03915,Q9Y2R0,P23786,P12235,P00403 10 +Glomerular deposits 0.6102833771545507 1.8819493872655773 0.0598428879278698 1.0 0.2051756157526966 2 P52565 1 +Localized osteoporosis 0.6102833771545507 1.8819493872655773 0.0598428879278698 1.0 0.2051756157526966 2 P82650 1 +Respiratory arrest 0.6834511246949833 1.881450483725443 0.0599106650103171 1.0 0.2052346992217251 7 Q96L58,P13473,P23786 3 +Abnormality of the tarsal bones 0.4749137820919458 1.8803756809283392 0.0600568955239408 1.0 0.2054507606342387 26 O75665,P16435,Q15125,Q8WVQ1,O75787,Q969X5,O75844,Q9UHX1 8 +Insulin resistant diabetes mellitus 0.6764316804434429 1.8759763778411735 0.0606585236387857 1.0 0.2072012430893438 8 O75844 1 +Emg abnormality 0.385988426802188 1.8742764181954927 0.0608923360746902 1.0 0.2072318202600979 80 Q8TB36,O14773,Q969X5,O43819,O15269,P07196,O43681,P07602,P42167,Q13510,P12235,Q9NZJ7,Q9NR77,Q96RL7,O60313,Q9NQ11,P13473,P03915,O95140,P50402,P09493 21 +Gastrointestinal hemorrhage 0.4687026744885266 1.8708092357965345 0.0613715270135115 1.0 0.2084008817083723 29 P21912,P49257,Q9NZ08,Q14739,O76024,Q8N5K1,P21964,Q9UHX1,Q8NBM4 9 +Dyschromatopsia 0.679904082458862 1.8630584079689791 0.0624540490905787 1.0 0.2116090133892549 7 Q9H061,Q9H6K4 2 +Spastic gait 0.5076286224337744 1.856706448206026 0.0633529296144739 1.0 0.2137117859908461 23 O75298,O75477,Q9NVI7,O94905,O75787,Q15043,O00400,Q15041 8 +Abnormality of the 5th toe 0.652459062673736 1.8499956230392225 0.0643141804440383 1.0 0.2160103835336574 11 Q96J42,O75845,Q14739,O43924,Q10713 5 +Postaxial foot polydactyly 0.652459062673736 1.8499956230392225 0.0643141804440383 1.0 0.2160103835336574 11 Q96J42,O75845,Q14739,O43924,Q10713 5 +Abnormal anterior chamber morphology 0.6661075008757822 1.8493995748945369 0.0644001367866118 1.0 0.2161368028497504 5 Q9Y2B2,Q8NCH0 2 +Undetectable visual evoked potentials 0.6491107249879331 1.847477978938861 0.0646778967806021 1.0 0.2169110250109275 4 Q8TC12 1 +Memory impairment 0.4379835025069121 1.8411817331153997 0.0655949313216417 1.0 0.2188714290587437 41 Q9NZJ7,O96008,Q8NBM4,Q9UJS0,Q9NZ08,P07602,P05067,P49770,Q969G3,P03886,P03915,O43681,P00403 13 +Lower limb spasticity 0.3824861543197375 1.8407961673920537 0.0656514346853887 1.0 0.2189014551593857 86 Q8N183,P21912,P04062,O75787,Q6DKK2,Q5XKP0,O75298,Q96CU9,Q9P0J0,P00846,P07602,Q7KZN9,Q9NZJ7,O75477,O60313,O94905,Q9NQ11,Q15041,Q9Y619,Q9H6K4,Q96DA6,O00400,Q9UBB4 23 +Aplasia hypoplasia of the capital femoral epiphysis 0.6642802852254404 1.8398497304974528 0.0657903019789185 1.0 0.2192058651618631 5 Q7LGA3 1 +Abnormality of head blood vessel 0.4699061448633895 1.8390546972408008 0.0659071413894742 1.0 0.219376797787098 26 Q9NZJ7,P00846,Q9Y4P3,P07602,P17900,Q13510,P03886,P03915,P21964 9 +Narrow nasal ridge 0.6693815404783967 1.838828768224448 0.065940375479836 1.0 0.219376797787098 8 O75844 1 +Muscle weakness 0.330988123246963 1.838529442589611 0.0659844274594005 1.0 0.219376797787098 303 Q8N183,P21912,Q86Y39,P40855,Q8TB36,Q9BQT8,Q9HC21,O96000,Q969X5,Q6DKK2,Q9NX14,O43819,O15269,Q9Y6M9,Q9UHX1,O43681,P23786,P13073,Q5XKP0,O43676,P53007,Q9Y276,O75298,P07196,Q10713,O95721,Q5T8D3,P00374,Q9P0J0,P00846,Q96CU9,Q3ZCQ8,P07602,Q15043,Q969G3,Q14118,Q13510,P05023,P12235,O95169,Q9NZJ7,P35670,Q9NR77,Q96RL7,O60313,O94905,Q8NCH0,Q70HW3,Q53H12,Q9NQ11,Q14739,Q13126,P03886,P13473,P03915,Q6NUK1,P00403,Q8NAT1,Q9NWM8,Q96DA6,O95140,Q9NPL8,O75381,P50402,Q8IUX1,Q68CQ7,O00400,Q15165,Q9Y375 69 +Mitochondrial respiratory chain defects 0.6806053467830814 1.837449158193385 0.0661436154833468 1.0 0.2193965179905105 6 P00846,P03886 2 +Hypothalamic hamartoma 0.6471977902384796 1.8372819852977311 0.0661682779152001 1.0 0.2193965179905105 4 O43924,O75665 2 +Lens luxation 0.6018112766579111 1.8340939648858583 0.066640047133887 1.0 0.2194871844281494 2 O96007 1 +Lower limb hyperreflexia 0.5269032505000163 1.8331363256993911 0.0667823001907348 1.0 0.2194871844281494 21 P13073,P21912,Q05086,Q9NQ11,O00400,Q15041 6 +Supernumerary bones of the axial skeleton 0.6740392480197234 1.8325691225656129 0.0668666735433973 1.0 0.2194871844281494 7 O75431 1 +Low back pain 0.6015191352614753 1.832439389291333 0.0668859841272444 1.0 0.2194871844281494 2 P54886 1 +Blurred vision 0.6795813776585989 1.832193256050876 0.0669226332729058 1.0 0.2194871844281494 6 P00846,P03886 2 +Abnormal large intestine physiology 0.5266748048325458 1.831494420067603 0.0670267798020554 1.0 0.2196724049273622 21 Q9NZJ7,O75298,Q8TAA9,P07602,P21964,O43681 6 +Paraparesis 0.466947647349099 1.8274661715163945 0.0676297080004391 1.0 0.220863001038996 27 P21912,P04062,Q5XKP0,Q9H6K4,O75787,Q13510,Q9NQ11,Q6DKK2 8 +Bilateral sensorineural hearing impairment 0.4683174900827491 1.8259093179280597 0.0678639224057684 1.0 0.2213141928137162 26 Q9NZJ7,Q96DA6,P07602,P03886,P00403 5 +Migraine 0.4682581546824466 1.8254180061944432 0.067937974112515 1.0 0.2213989990880262 26 Q9NQZ5,Q8NBM4,O60313,Q9NZ08,P03886,P03915,P12235,P00403 8 +Abnormality of visual evoked potentials 0.5144324360729167 1.8230843004106303 0.0682906240155569 1.0 0.2222338951014735 22 Q9NZJ7,Q15067,O75503,O60313,O95140,P07602,Q8N766,Q8TC12,Q9NP72,Q9NRG9,Q9H2M9,O43681 12 +Posterior subcapsular cataract 0.6719641499206047 1.8217579172726248 0.0684917256733224 1.0 0.2227310316885459 7 Q96HR9,Q9H6K4 2 +Progressive psychomotor deterioration 0.65958189916126 1.818918837630074 0.0689238134391654 1.0 0.2239780904990651 9 P21912,Q9NZJ7,O43681,P07602 4 +Male pseudohermaphroditism 0.6598222304990915 1.8165094511225248 0.0692922594838829 1.0 0.2247756959082668 5 P53701,Q96J42 2 +Hypokinesia 0.6396712639615182 1.81635720436153 0.0693155954612949 1.0 0.2247756959082668 12 P04062,Q2TAA5,P13473,Q9NQ11,P06753,Q9Y3D3,P12235 7 +Recurrent acute respiratory tract infection 0.6197993434453315 1.8107110383620288 0.0701855932697843 1.0 0.2267988876487842 3 Q03519 1 +Abnormality of alkaline phosphatase level 0.5006735639268464 1.8039611959768511 0.0712373903266003 1.0 0.2284355564544012 23 Q9Y2B2,Q9H9E3,Q96A33,Q8N511,Q96S52,O75845,Q92643,Q14739,Q96JJ3 9 +Abnormality of globe size 0.3794078051331974 1.7985221933782318 0.072094294905987 1.0 0.2303817690199642 70 Q96J42,Q96RT7,P11166,Q9NP72,Q9NX14,Q9UHX1,O60566,Q14118,P21964,Q9H2M9,O43505,Q12797,Q9BYC5,P53701,O75569,P30533,Q15645,O43924,Q96I36,Q6NUK1,O43175,Q8NAT1,O75431,Q15125,P52732,Q2M1P5 26 +Subcutaneous hemorrhage 0.424665302979322 1.795085225817976 0.0726401222998021 1.0 0.2316440716660817 44 P35670,P60033,P49257,Q9NWM8,Q8NCH0,Q8N6S5,Q14108,Q13126,P21964 9 +Low set posteriorly rotated ears 0.3796568656495889 1.79450125602344 0.0727331983171302 1.0 0.2317804826039668 75 O75665,P40855,P16435,Q9UM00,O95202,Q96L58,Q9Y4P3,Q96J42,Q8WVQ1,Q8NCH0,P37268,O75381,Q15392,O43924,Q6NUK1,Q10713 16 +Retinal detachment 0.5211540706948612 1.7917319434811387 0.0731759150665796 1.0 0.2324676244497122 21 Q96RT7,Q8N6S5,Q8NCH0,Q8NAT1 4 +Basal ganglia calcification 0.6530224371553565 1.7836343570041595 0.0744830990274176 1.0 0.2343234230187881 9 O60313,P00403,P03886 3 +Hypopigmented skin patches 0.4626899437538359 1.7792037180789373 0.0752063690379574 1.0 0.2347891209633824 26 P21912,Q8IZA0,Q9NZJ7,Q15125,P53701,P07602,P21964 7 +Bilateral cleft lip 0.6136762127410863 1.7769251453784871 0.0755805565611296 1.0 0.2347891209633824 3 Q9NXE4,O60716 2 +Underdeveloped supraorbital ridges 0.6390753956157065 1.775841664164516 0.0757590183008534 1.0 0.2349243313124714 11 P16435,P40855,O75381,P56589,Q6PGP7,Q6NUK1 6 +Chronic pulmonary obstruction 0.662599225356199 1.7728155394204457 0.0762592776143864 1.0 0.2360410884568232 7 P09601 1 +Neoplasm of fatty tissue 0.637896357289468 1.769282028682741 0.0768468209817665 1.0 0.2366967926340916 11 P21912,Q9Y2U8,P03915,Q8TAA9 4 +Basal ganglia cysts 0.6618690955834914 1.7689894349601878 0.0768956377112055 1.0 0.2366967926340916 7 P00846 1 +Dilated cardiomyopathy 0.4029728057344464 1.7686345080463004 0.0769548881185597 1.0 0.2367210443593614 50 P09493,P13473,Q96RL7,P53701,Q96DA6,P00846,P42167,P03886,Q9NX14,P03915,O43819,P23786,P12235,P00403 14 +Abnormal oral mucosa morphology 0.3738066333615314 1.75690883596803 0.0789333493147099 1.0 0.2415171803732958 62 Q9NUN5,O75431,Q9Y5U9,P49257,Q8NBM4,Q96S52,Q9Y4P3,Q9NZ08,O75845,Q8N766,Q14739,Q14108,Q5JRA6,Q15392,Q96JJ3,Q9UM00 16 +Schizophrenia 0.5261377407372123 1.7513662891728312 0.0798828358944396 1.0 0.2437749058288596 20 Q9NZJ7,P07602,Q9BQE5,P16615,O76024,P21964,O43681 7 +Sunken cheeks 0.6086402598025453 1.7490495180982084 0.080282460241247 1.0 0.2448322811328038 3 P04350 1 +Abnormal caudate nucleus morphology 0.6339699240251964 1.7474059235828625 0.0805669506945296 1.0 0.2453750884338352 11 Q96RL7,Q9NQ11,O43819,P00846 4 +Tinnitus 0.5700311316930478 1.7426761860489863 0.081390193681442 1.0 0.2472287491655142 16 P21912,Q9NR28,Q9NR77,O95140,Q15043,Q969G3 6 +Progressive sensorineural hearing impairment 0.6262206477620651 1.740364168091531 0.0817950931592637 1.0 0.2482949863490692 12 O60313,O60443,O76024,P03886,P00403 5 +Retinal pigment epithelial atrophy 0.6289170946600438 1.739293727968694 0.0819831099991283 1.0 0.2487018899776061 4 P51648 1 +Pigmentary retinopathy 0.3967689788690915 1.738969709522607 0.0820400910935028 1.0 0.2487110129992507 51 Q8N183,P21912,Q96CU9,Q9P0J0,P00846,P53701,Q9UG56,Q7KZN9,Q96S66,Q8WWY3,O76024,P03886,P03915,P00403 14 +Hyperlipidemia 0.4493545658819847 1.736015468255632 0.0825610995472998 1.0 0.248793480832538 31 O95470,O75844,O75431,P49257,P50416,P50402,P22830 7 +Abnormality of the tonsils 0.6552989118212121 1.7344929945250511 0.0828306476769562 1.0 0.248793480832538 7 P00813 1 +Progeroid facial appearance 0.6548644700765006 1.7322077710819308 0.08323657591655 1.0 0.2493353504929158 7 O75844 1 +Cns demyelination 0.5972375611817322 1.7319758884213177 0.0832778555428777 1.0 0.2493353504929158 14 P40855,Q9NZJ7,P07602,P49770,Q9NR50,P51648 6 +Retinal telangiectasia 0.6597819068760459 1.7299990779150625 0.0836304399718543 1.0 0.2500772663142797 6 P00846,P03886 2 +Morphological abnormality of the corticospinal tract 0.5527243226965883 1.7275641367147083 0.0840663971848794 1.0 0.2507626278630879 17 Q9Y4P3,P00846,O75298 3 +Abnormal circulating pyruvate family amino acid concentration 0.4906566760848144 1.727503298077257 0.0840773133785743 1.0 0.2507626278630879 23 O75880,Q5XKP0,P20674,Q9BUB7,P22695,Q9P0J0,P00846,O96000,Q8IUX1,P03886,P03915 11 +Cystic liver disease 0.6590383087863745 1.726140314914756 0.0843221725178393 1.0 0.2510433330832878 6 O75665,Q96J42 2 +Oligohydramnios 0.4310090324894023 1.725771571405735 0.0843885161647175 1.0 0.2510433330832878 39 Q9Y2B2,P16435,Q9BUB7,Q96L58,Q7LGA3,Q96J42,Q969X5,P23786,Q96I36,Q9UHX1,Q6NUK1 11 +Saccadic smooth pursuit 0.6263517856016201 1.7254643146339912 0.084443829487651 1.0 0.2510433330832878 4 O14773 1 +Ureteral duplication 0.6520320250920656 1.717296014261607 0.0859250999264806 1.0 0.2536469317496623 7 O75844,P23786,Q96J42 3 +Progressive spastic quadriplegia 0.6346107385134296 1.7163737676535062 0.0860936546310982 1.0 0.2536570080179671 10 Q9NQ11,Q9NZJ7,O43681,P07602 4 +Retinal coloboma 0.6442793739668443 1.7053945994666442 0.0881208548888581 1.0 0.2583065323479127 8 Q9Y2B2,Q9NP72,Q9UHX1,Q10713 4 +Corneal dystrophy 0.6544136231042584 1.7021082811392878 0.0887350718275841 1.0 0.2592842174898589 6 Q53H12,P12235 2 +Periventricular white matter hyperintensities 0.6378946036146381 1.7017763953851928 0.0887972930159184 1.0 0.2593016008981952 9 Q9NZJ7,O43681,P17900,P07602 4 +Limb girdle muscle weakness 0.4760633634823842 1.7002801963782217 0.0890782336465203 1.0 0.2597927219260543 24 Q9NZJ7,O60313,P07602,Q13126,P12235 5 +Symphalangism of middle phalanx of finger 0.577855682150171 1.697465174362656 0.0896087498126281 1.0 0.2605155325782904 2 Q15233 1 +Abnormality of the proximal phalanx of the thumb 0.577855682150171 1.697465174362656 0.0896087498126281 1.0 0.2605155325782904 2 Q15233 1 +Visual impairment 0.3281150299083654 1.694161541021292 0.0902345907108628 1.0 0.2613456907577975 294 Q8N183,P21912,Q86Y39,P40855,O75665,Q9Y375,Q96A33,Q7LGA3,Q9NZ08,Q96RT7,O96000,O14773,P37268,Q8WWY3,Q9NX14,Q9H061,O43819,Q01105,Q9Y6M9,Q9UHX1,O43681,Q10713,Q5XKP0,O43676,P53007,Q96CU9,P00846,Q9Y4P3,Q15907,P07602,Q8N766,Q9H490,P49770,Q15043,Q969G3,Q5BJH7,Q96AA3,P12235,Q9NWW5,O95169,Q9NZJ7,Q96N66,P53701,O60313,P17900,Q9NR50,Q96S66,Q8TC12,O43292,P03886,P13473,P03915,P00403,Q8NBM4,Q6P4A7,Q9H6K4,Q96S52,P50897,Q9NPL8,O95140,O75381,Q8IUX1,Q96HR9,Q96JJ3,Q9Y2U8 65 +Molar tooth sign on mri 0.6472840840707764 1.69225077146336 0.0905981697590536 1.0 0.261914013140916 7 O43924,O75665,Q10713 3 +Unexplained fevers 0.6525166228541672 1.6922341805994272 0.0906013318026519 1.0 0.261914013140916 6 P07602 1 +Atrophy degeneration involving the corticospinal tracts 0.576361679883722 1.69103548088884 0.090830026343937 1.0 0.262293269277151 15 Q9Y4P3,P00846,O75298 3 +Abnormality of circulating leptin level 0.6198241337493663 1.690188361034036 0.0909919243523049 1.0 0.2625490215500446 4 O75844,P02545 2 +Hyperintensity of cerebral white matter on mri 0.5068769628587872 1.688170135701866 0.0913785742208823 1.0 0.2626398858398797 21 P21912,Q9NZJ7,P07602,P17900,Q15043,Q96AA3,O43681 7 +Abnormality of the phalanges of the toes 0.5273031106392628 1.688106712802163 0.0913907460959519 1.0 0.2626398858398797 19 Q9Y2B2,O75844,Q7LGA3,O75431 4 +Abnormal tongue morphology 0.3709024413332396 1.6830599236880848 0.0923634916496582 1.0 0.2651781741567759 78 P21912,O75665,Q05086,Q9NUN5,O75431,Q96RL7,Q96A33,Q7LGA3,Q9Y4P3,Q96J42,Q96S52,O43924,O75844,Q6NUK1,P07196 15 +Degeneration of the lateral corticospinal tracts 0.6451563263042183 1.6810071034264682 0.0927615348178618 1.0 0.2661551385060445 7 O75298 1 +Abnormal response to endocrine stimulation test 0.6180200077843458 1.6804171862901454 0.09287617450988 1.0 0.2663182402871981 4 P16435 1 +Generalized clonic seizure 0.6493301450422564 1.6756269039416591 0.0938112955967276 1.0 0.2686652890675705 6 P07602 1 +Ophthalmoparesis 0.3697299618998227 1.669321331883285 0.095053714842259 1.0 0.2705420123490608 82 Q8N183,P21912,P04062,O75665,Q8WWY3,O76024,O43819,Q10713,P53007,Q96CU9,Q9P0J0,P00846,Q7KZN9,Q969G3,P12235,O60313,P03886,P03915,P00403,Q8N5K1,Q96HR9 21 +Pancreatic cysts 0.6480357856402958 1.6688733809675385 0.0951424760170014 1.0 0.2706274873372485 6 Q96J42 1 +Congenital hepatic fibrosis 0.6317405656493663 1.6681918262002835 0.0952776529814765 1.0 0.2706778205540343 5 Q96J42 1 +Central hypoventilation 0.6424917858898793 1.666909774997922 0.0955323469011359 1.0 0.2712341679115432 7 Q8N183,P06753,O43819,O95169 4 +Recurrent paroxysmal headache 0.625502532988024 1.6660811860138565 0.0956972452703286 1.0 0.2715350407670408 10 P21912,P03915,P00403,P03886 4 +Mucosal telangiectasiae 0.6309828390969416 1.6641565609893136 0.0960811463540003 1.0 0.2721799429823491 9 P21912,Q8IZA0,Q14739 3 +Abnormal metabolic brain imaging by mrs 0.5334773811394363 1.6632170852657977 0.0962689888394656 1.0 0.2724625502857071 18 P21912,Q9NZJ7,P07602,P03886,P03915,O43819,P00403 7 +Abnormal drinking behavior 0.6147466942848675 1.6626653087018484 0.0963794501298496 1.0 0.2724641142321147 4 Q8N5K1 1 +Functional abnormality of the inner ear 0.3382988153799925 1.6620634965861494 0.0965000437361101 1.0 0.2725290850733713 260 Q8N183,P21912,P04062,Q86Y39,P40855,O75665,Q9NR28,Q16740,Q7LGA3,Q9NZ08,O60443,O96000,Q8WWY3,O76024,Q9NX14,Q9H061,O15269,Q9Y6M9,O43681,P07196,Q5XKP0,O43676,P53007,O95470,O95721,Q2TAA5,O95202,Q96CU9,P00846,Q9Y4P3,P07602,P42167,P42892,Q13510,Q96AA3,P12235,Q9NZJ7,O00165,P51572,Q9NR77,Q9UG56,O60313,P03886,P03915,O75844,P00403,Q8NBM4,Q15125,Q96L58,Q9NWM8,Q96DA6,O95140,Q9NPL8,O75381,Q8IUX1,Q5JRA6,Q8N5K1,Q96HR9,Q96JJ3,Q9Y375,P09493 61 +Asymmetry of the thorax 0.5714285714285825 1.6604874496870494 0.0968164306130796 1.0 0.2725290850733713 2 Q14696 1 +Sirenomelia 0.5714285714285824 1.6604874496870483 0.0968164306130798 1.0 0.2725290850733713 2 P21281 1 +Central heterochromia 0.5714285714285823 1.660487449687046 0.0968164306130803 1.0 0.2725290850733713 2 Q8IY17 1 +Angioid streaks of the fundus 0.5714285714285823 1.660487449687046 0.0968164306130803 1.0 0.2725290850733713 2 P38435 1 +Macrodactyly 0.5714285714285756 1.6604874496870086 0.0968164306130878 1.0 0.2725290850733713 2 O00170 1 +Transposition of the great arteries 0.6461851880497037 1.6592100313434832 0.0970734769189365 1.0 0.2728041495095578 6 Q9Y2B2,O75844 2 +Postaxial hand polydactyly 0.5568013560804133 1.658024310712602 0.097312559563659 1.0 0.2732579369100187 16 O75665,Q10713,Q96J42,O75845,O43924,Q9UM00 6 +Anterior open bite malocclusion 0.5705521472392748 1.6554347959379825 0.0978363326346247 1.0 0.2742273849028899 2 P21281 1 +Metabolic alkalosis 0.570260005842839 1.6537500365046611 0.0981783114815344 1.0 0.2750186378765414 2 P04150 1 +Abnormal renal physiology 0.345163485773082 1.6532116846767968 0.0982877892489881 1.0 0.2751580394042148 172 Q8N183,P21912,P04062,Q86Y39,P40855,O75665,Q9Y375,Q9BRT2,P49257,Q9NZ08,O96000,P50416,O76024,Q9BT22,Q9NX14,O43819,Q9Y6M9,P23786,Q10713,O95721,O43676,O95470,Q9Y276,Q8TAA9,Q96CU9,P00813,P09601,Q9Y4P3,Q14108,P05023,O95169,P35670,P60033,Q8NCH0,Q15645,P03886,P03915,P00403,Q8NBM4,Q96D53,Q9NPL8,Q8IUX1,Q8N5K1,Q9Y2U8 44 +Chorioretinal dysplasia 0.6344893470755477 1.6528721685741337 0.098356882442677 1.0 0.2751842831183095 8 Q8NAT1,O43505,P53701,Q96RT7,Q14118,Q9NX14 6 +Abnormality of the musculature of the lower limbs 0.4430609152015617 1.6517452619925286 0.0985864915461642 1.0 0.2754359451645384 29 P53007,Q9BTV4,Q8NAT1,Q9NR77,Q96RL7,P00846,P02545,Q9NQ11,P50402,Q14118,Q9NRG9,Q12768,P07196 13 +Hemianopia 0.6164183080920763 1.649039828053602 0.0991394755064498 1.0 0.2761999414351396 11 P03915,P00403,P03886 3 +Dental crowding 0.4690990282126792 1.6451165598943591 0.0999457762121094 1.0 0.278278028269124 24 O75431,Q96A33,Q92643,P36543,Q01105,O75844,Q15738,P02545 8 +Frequent falls 0.419998249658435 1.6445736028928255 0.100057774224805 1.0 0.2784216326255443 40 P21912,P04062,Q9NZJ7,Q9NR77,P00846,O95140,P07602,O75787,O43819,Q13510,P12235,O43681 12 +Intracellular accumulation of autofluorescent lipopigment storage material 0.6112715226101216 1.643785744668835 0.1002204669737893 1.0 0.2787060421335072 4 O14773,Q9NWW5 2 +Airway obstruction 0.5685211876715647 1.642234837600297 0.1005413455080406 1.0 0.2791936548292555 15 Q96HY6,O75665,P09601,O75844,P21964 5 +Variable expressivity 0.3675575898040069 1.6421987834046132 0.1005488147525932 1.0 0.2791936548292555 83 P11166,Q9H061,P07196,O95470,Q9Y276,Q9NWS8,P00374,Q8WVQ1,P07602,Q8NI60,Q14118,P09622,Q13510,Q9NZJ7,Q9NR77,Q70HW3,P17900,O60762,Q53H12,P03886,P03915,P00403,Q6P4A7,Q15125,P33993,P52732,O95140,Q9Y375,P02545 29 +Micrographia 0.589439524670784 1.642050795390679 0.1005794776392772 1.0 0.2791936548292555 3 Q96RL7 1 +Sclerocornea 0.6148865839169221 1.6404115332327325 0.1009196289280163 1.0 0.2792567672866932 11 O95202,P53701,Q6NUK1,Q96J42 4 +Abnormal sternal ossification 0.6099028639909763 1.6363409925559385 0.1017682413193776 1.0 0.2811439184650433 4 O95202 1 +Abnormal foot bone ossification 0.6097640388532344 1.6355855698244322 0.101926352468372 1.0 0.2814120025010534 4 Q8WVQ1,Q15125 2 +Aplasia hypoplasia of the sternum 0.6096453918774127 1.6349399051215718 0.1020616460234005 1.0 0.2815763847320418 4 Q9Y619,O60566 2 +Progressive pes cavus 0.6408085647878273 1.6310845677402828 0.1028724764961532 1.0 0.283345111592513 6 O00400,Q9NQ11,O75298 3 +Inverted nipples 0.6303451197219165 1.630559874483653 0.1029832216806023 1.0 0.2834806962390774 8 Q15067,P56589,Q2TAA5,Q96AA3 4 +Proximal muscle weakness 0.3642632009636602 1.6246596543051062 0.1042350985684665 1.0 0.2859019846449369 66 P21912,P53007,Q8NAT1,P35670,Q8TB36,Q9BQT8,P00846,O60313,O95140,P50402,Q13126,Q14118,P13473,Q13510,P12235,P07196 16 +Cardiac conduction abnormality 0.4328079811374475 1.6225538140083198 0.104684820469219 1.0 0.2866236795734766 33 P21912,Q9HD47,P00846,Q9H490,P50402,P03886,O43819,P23786,P00403 9 +Multicystic kidney dysplasia 0.4871736967354512 1.6197270288974226 0.1052909273843214 1.0 0.2877702214631988 22 O75665,P40855,Q96J42,O75381,O60566,Q15645,Q8N6S5,Q10713 8 +Papule 0.5073688848706959 1.617944202834376 0.1056746229906993 1.0 0.2885988646435635 20 P21912,Q9NZ08,P16615,O75844,Q9Y2U8 5 +Bulbous nose 0.4062131999049887 1.6113929747190787 0.1070940974814453 1.0 0.2906299182535338 44 Q9Y2B2,P16435,O75431,Q96A33,O75845,P21964,P23786 7 +Biparietal narrowing 0.57704767747059 1.6100419663285117 0.1073886949562137 1.0 0.2909492911029868 14 Q96RT7,O75665,O43924,O75845 4 +Flat nasal alae 0.5626643295354999 1.6098522248174905 0.1074301208650356 1.0 0.2909492911029868 2 P18074 1 +Abnormality of amino acid metabolism 0.5626643295354999 1.6098522248174905 0.1074301208650356 1.0 0.2909492911029868 2 P18074 1 +Positional foot deformity 0.3600854730813831 1.6096955212744428 0.1074643431981952 1.0 0.2909492911029868 101 O75665,Q8TB36,Q9HC21,Q96A33,Q96J42,Q969X5,Q9UHX1,P07196,P16435,Q8TAA9,Q9NVI7,O95202,Q15907,Q8WVQ1,P21964,Q6ZXV5,Q96DF8,Q9NR77,Q8NCH0,O75845,Q9UM00,Q9H9E3,Q15125,Q96L58,Q9NWM8,Q15392,Q8NBU5 27 +Duodenal adenocarcinoma 0.5623721881390699 1.608160265882559 0.1078000829612877 1.0 0.2916788943736629 2 P78549 1 +Congenital hypothyroidism 0.6204379931843309 1.6078847404419965 0.1078604244819274 1.0 0.2916788943736629 5 Q9NNW7,P10644,Q13423 3 +Orchitis 0.6041073234079604 1.604759240618964 0.1085467991312554 1.0 0.2925705407300824 4 Q9NZ08 1 +Neuroinflammation 0.6041073234079604 1.604759240618964 0.1085467991312554 1.0 0.2925705407300824 4 Q9NZ08 1 +Pleuritis 0.6041073234079604 1.604759240618964 0.1085467991312554 1.0 0.2925705407300824 4 Q9NZ08 1 +Gait ataxia 0.364051987166582 1.601950296382101 0.1091666010135092 1.0 0.2933176078543736 73 Q05086,Q9NZJ7,Q9NVI7,Q10713,Q9NR77,Q8IV08,P00846,Q15907,P07602,O14773,Q9NQ11,Q14108,O43292,P03886,P03915,P12235,P07196,O43681 18 +Physical urticaria 0.5612036225533221 1.6013898083262146 0.1092906086467468 1.0 0.2934796763660895 2 Q6P1M0 1 +Nodular goiter 0.5609114811568917 1.599696540059873 0.109665919803582 1.0 0.2938026502644804 2 Q9UNW1 1 +Limitation of movement at ankles 0.6024932826842018 1.5959475162272203 0.1105005115792066 1.0 0.2951804970185414 4 O75844 1 +Abnormality of facial adipose tissue 0.602126150195629 1.593942204437813 0.1109489804115004 1.0 0.295692829228568 4 O75844,P02545 2 +Recurrent aspiration pneumonia 0.632856233536356 1.589350901583393 0.1119811928006857 1.0 0.2976759417184886 6 Q13510,Q6NUK1 2 +Preaxial foot polydactyly 0.6009902943033791 1.587735759096759 0.1123461033727604 1.0 0.2976982783351538 4 O95202 1 +Thickened skin 0.3569124600180677 1.5872174220973794 0.1124634102414094 1.0 0.2978341347082844 104 Q9Y2B2,P21912,P40855,P16615,O15269,O95721,O95470,P00813,P42167,P51648,Q14739,O75844,O75431,Q15125,Q9NWM8,O75381,P50402,P98194,Q96JJ3,Q15800,Q9Y2U8,P09493 22 +Abnormal circulating carbohydrate concentration 0.4064441108228613 1.586838651088557 0.1125491924380062 1.0 0.2978901084171927 43 Q8N183,P21912,Q86Y39,O43676,Q9Y276,P22695,Q96CU9,Q9NPL8,Q70HW3,O96000,Q8IUX1,Q9BWD1,P03886,Q9NX14,Q9Y6M9,Q9Y375 16 +Progressive hearing impairment 0.5454866704937005 1.585090377188418 0.1129458016160611 1.0 0.2987682283850802 16 O60313,O60443,O76024,P03886,P00403 5 +Pneumothorax 0.62064627195842 1.578162694772549 0.1145282380875989 1.0 0.3012249549701232 8 Q9H078,Q96L58,Q8NCH0,P36543,Q6NUK1 5 +Abnormality of the umbilical cord 0.6147341185556355 1.575192510154439 0.1152120155062532 1.0 0.3025053945600086 9 Q9Y2B2,P16435,O75844,Q12768,P02545 5 +Venous malformation 0.5559450774174811 1.570871327384869 0.1162125398834896 1.0 0.3037022671331933 2 P31749 1 +Vitiligo 0.6188382165578484 1.5683675925796 0.1167953696938552 1.0 0.3045801151948416 8 Q8N766,P00403,P03886 3 +Slow decrease in visual acuity 0.5957165155650507 1.5659218103990862 0.1173669231489107 1.0 0.305446727602111 12 P03915,O95140,P00846,P03886 4 +Primary adrenal insufficiency 0.5097239649375929 1.5655281813230102 0.1174591148678256 1.0 0.305446727602111 19 P16435,P40855,Q9Y2R9,O75381,P56589,Q9H0R6,Q969G3,Q9NRG9,Q13423 9 +Abnormal circulating fatty acid concentration 0.5096217550374044 1.5648115199746069 0.1176271097909222 1.0 0.3054965405168348 19 O75880,P40855,Q9NUN5,O75431,P23786 5 +Disproportionate short limb short stature 0.4798653599097864 1.56454148567679 0.1176904582987701 1.0 0.3054965405168348 22 Q15125,Q7LGA3,Q8WVQ1,O00116,Q14739,Q15392 6 +Retinal dystrophy 0.3586750887676592 1.5643156512477798 0.1177434583241967 1.0 0.3054965405168348 64 O75665,P40855,Q15067,Q96RT7,P56589,Q8WWY3,Q9NX14,Q10713,Q9Y276,Q5T8D3,P00846,Q8N2K0,Q14118,P53701,Q8TC12,P03886,P03915,Q8NAT1,O75381,Q96HR9 20 +Abnormal palmar dermatoglyphics 0.3587357197482624 1.5606722284084278 0.1186011070866146 1.0 0.3072584762611445 65 P40855,O75431,O95202,Q96S52,Q8NCH0,Q15907,O75381,Q96I36,Q9UHX1,Q6NUK1 10 +Intellectual disability progressive 0.5688878929504914 1.5603716455076613 0.1186720813899671 1.0 0.3072584762611445 14 O95721,O75665,Q05086,Q15067,P53701,Q9H9P8,Q9NX14 7 +Spastic paraparesis 0.4991221254061162 1.5587983816258362 0.1190441073860704 1.0 0.307671249370623 20 P21912,P04062,Q5XKP0,Q9H6K4,O75787,Q6DKK2 6 +Prolonged partial thromboplastin time 0.6112804112176756 1.5587776750791915 0.1190490099018708 1.0 0.307671249370623 5 P49257,P28288 2 +Respiratory failure 0.3589492395343884 1.5516916304143369 0.120736026281333 1.0 0.3108359703083926 68 Q8N183,O75665,Q5XKP0,O95169,Q9NZJ7,Q9BUB7,P53701,Q15165,Q70HW3,P07602,Q8NBU5,Q68CQ7,Q9BT22,Q14118,Q9NX14,O43819,Q13510,P23786 18 +Aplasia hypoplasia involving the femoral head and neck 0.6087571449473242 1.5422886853651203 0.1230034572273877 1.0 0.315590161973164 9 Q96L58,Q8WVQ1,O75431 3 +Upper limb asymmetry 0.5715955581531176 1.5416368649967538 0.1231618619173118 1.0 0.3156837799834602 3 P07437,Q15555 2 +Ectopic calcification 0.3551309997812237 1.5413254176000435 0.1232376057520499 1.0 0.3156837799834602 60 P40855,P04062,P35670,O75431,Q15125,O60313,O75845,O75381,O00116,Q14739,Q14118,P03886,P03915,O75844,P23786,P00403 16 +Cerebral dysmyelination 0.6188490909363636 1.5410115434950138 0.1233139765560391 1.0 0.3156837799834602 7 P07602 1 +Posteriorly rotated ears 0.3474275639256512 1.538687782254041 0.1238805364720829 1.0 0.3162905333592977 113 O75665,P40855,Q7LGA3,Q96J42,P37268,P23786,Q9UHX1,Q10713,P16435,O95202,Q9Y4P3,Q8WVQ1,Q9H490,O60566,Q14118,Q8NCH0,O43924,Q6NUK1,Q9UM00,Q8NAT1,Q96L58,Q96S52,O75381,Q15392 24 +B cell lymphoma 0.606488939574257 1.5329990867406509 0.1252760799289971 1.0 0.3181321026693851 5 P00813 1 +Abnormal metatarsal morphology 0.4334196902190149 1.5328565454222995 0.1253112047037485 1.0 0.3181321026693851 26 Q9H9E3,P16435,Q8NAT1,O95202,Q96L58,Q96S52,Q8WVQ1,Q14118,Q15392 9 +Subcapsular cataract 0.6122626934804027 1.5326743900365345 0.1253561022772253 1.0 0.3181321026693851 8 Q96HR9,Q9H6K4 2 +Severe demyelination of the white matter 0.5492258252994586 1.5317554690099984 0.1255827886816782 1.0 0.3183088505198974 2 Q9H9P8 1 +Abnormal glomerular mesangium morphology 0.465285780846988 1.5313431287446275 0.1256846116728154 1.0 0.3183918035120029 23 O95470,P00813,Q96D53 3 +Hyperreflexia in upper limbs 0.6066492411977501 1.5306622432807826 0.1258528898059481 1.0 0.3186429210031917 9 P21912,Q9NQ11,O75298 3 +Clonic seizure 0.6167874569327861 1.5299664592262825 0.1260250313404185 1.0 0.3188719206786702 7 P07602 1 +Mania 0.5505597188431184 1.5296161669791433 0.1261117653193861 1.0 0.3188719206786702 15 P16615,P03886,P03915,P21964,P12235,P00403 6 +Psychomotor deterioration 0.6062389298816612 1.5283977829681663 0.1264138049523893 1.0 0.3192928058446774 9 P50897,P07602 2 +Positive romberg sign 0.6060216228838409 1.527198316191086 0.1267117048964003 1.0 0.3194133129992412 9 Q8IV08,Q9H6K4,P07196 3 +Pericardial effusion 0.6210069195534275 1.52687715690608 0.1267915607950598 1.0 0.319439864485312 6 P04062,Q14108,P02545 3 +Increased adipose tissue 0.5896797425495865 1.5257477942272553 0.1270726866870035 1.0 0.3197984381505802 4 P02545,O75431 2 +Neurogenic bladder 0.6047723597232523 1.5203004327432763 0.1284354853338094 1.0 0.3223478847593649 9 Q8TAA9,Q9NQ11,O76024,Q8N5K1,P50336 5 +Supranuclear gaze palsy 0.493534993046089 1.5185541414981776 0.1288747616789172 1.0 0.3230081870956178 20 Q9NZJ7,Q96RL7,O15118,P07602,Q9NQ11 5 +Macular degeneration 0.5749022347170228 1.5182748129966084 0.1289451344140724 1.0 0.3230081870956178 13 P51648,P04062,Q13510,P50897 4 +Skin dimple 0.4300382347368609 1.5147475253933602 0.1298363538950999 1.0 0.3242742107038594 27 Q8TAA9,Q15125,O95202,P53701,Q9Y4P3,Q969X5,Q9UM00 7 +Dysuria 0.6087153486463526 1.513373649045264 0.1301847745376305 1.0 0.3248734533951142 8 Q8N5K1 1 +Equinovarus deformity 0.6184298477177843 1.5132455845422397 0.1302172891538142 1.0 0.3248734533951142 6 Q96RL7,Q969X5 2 +Abnormal dermatoglyphics 0.357275952945776 1.5078965095166317 0.1315810161432589 1.0 0.3270291520595998 79 Q9Y2B2,O75665,P40855,O75431,O95202,Q96S52,Q9Y4P3,Q8NCH0,Q15907,O75381,Q96I36,Q9UHX1,Q6NUK1 13 +Myopathy 0.350769726416163 1.5077672654182444 0.1316141028965538 1.0 0.3270291520595998 105 P21912,Q86Y39,Q969X5,O76024,P23786,O43676,P00846,Q9Y4P3,P42167,P12235,Q96RL7,O60313,Q8NCH0,Q53H12,Q13126,P03886,P13473,P00403,Q9NWM8,P50402,Q8N5K1,P09493 22 +Aplasia hypoplasia of the nasal bone 0.5652924077551097 1.505954643430559 0.1320788175372711 1.0 0.3276566642724969 3 Q6NUK1 1 +Impaired visuospatial constructive cognition 0.6073274111772101 1.5058135839211213 0.132115035203624 1.0 0.3276566642724969 8 Q10713,P00403,P03886 3 +Abnormality of the alveolar ridges 0.6018764220476045 1.5042951091158694 0.1325053978495431 1.0 0.3284480222112399 9 O75665,Q2M1P5,P53634,Q15392,O43924,P98175 6 +Absent epiphyses 0.6164284442840373 1.5026483962957515 0.1329297363486643 1.0 0.3292523458496117 6 Q7LGA3 1 +Polydactyly 0.3648609967144832 1.4984262104996695 0.1340225507987058 1.0 0.3306080910494842 54 O75665,Q9UM00,Q15125,O95202,Q9BRT2,Q96J42,O75845,Q14739,O43924,P21964,Q9UHX1,Q10713 12 +Dermal atrophy 0.4222802614974247 1.4974343951167886 0.1342802641913723 1.0 0.3306355209352238 31 Q96L58,Q9NWM8,P53701,Q8NCH0,Q15392,O75844,Q9Y2U8 7 +Abnormal pleura morphology 0.4505784051334631 1.4970692983842682 0.1343752273912672 1.0 0.3306355209352238 24 Q9H078,Q96L58,P52732,Q9NZ08,Q8NCH0,Q14739,P36543,Q13043,P14174,Q93063,Q6NUK1,Q9UID3,Q8NBM4 13 +Abnormal sensory nerve conduction velocity 0.615252070724401 1.4964153405405891 0.1345454543799877 1.0 0.3306355209352238 6 Q9NR77,O15269,O95140 3 +Insulin resistance 0.5090798916434761 1.4964152497524117 0.1345454780239634 1.0 0.3306355209352238 18 O75431,Q03252,O95140,P18031,O76024,O75844,P02545 7 +Congenital bilateral hip dislocation 0.5430908559743046 1.4959269669612845 0.1346726880405997 1.0 0.3306355209352238 2 Q9Y4R8 1 +Epiphyseal stippling 0.5835486655567785 1.4955701482449413 0.1347657071208026 1.0 0.33067112801526 12 P40855,Q15125,O75381,O00116,Q14739,Q15738 6 +Limb muscle weakness 0.3559096952886079 1.4929149168668834 0.1354594599300134 1.0 0.3321964828938274 86 Q8TB36,Q9BQT8,Q15067,Q969X5,O43819,O15269,P07196,P53007,O75298,Q96BR5,P00846,Q969G3,Q13510,P05023,P12235,P35670,Q9NR77,Q96RL7,O94905,Q14739,Q13126,Q12768,Q9BTV4,O95140,P50402,O00400,P50336,P02545 28 +Adenocarcinoma of the small intestine 0.5625365283459897 1.4903202938525704 0.1361400389676874 1.0 0.3333333153895344 3 Q6PD74,P78549 2 +Recurrent bronchitis 0.6139951421730614 1.4897519708503977 0.1362894639907137 1.0 0.3335219596756287 6 P60033,Q9H0U3 2 +Ankle clonus 0.5568847452766127 1.4869185785320234 0.1370363167682298 1.0 0.3349938183915135 14 Q9NZJ7,O75298,P07602,O75787,Q15043 5 +Increased intracranial pressure 0.4791703986256297 1.4843167499110863 0.1377249087167098 1.0 0.3363202858328558 21 P21912,Q9NZJ7,Q9NZ08,P07602,Q96JJ3,Q8NBM4 6 +Hypoparathyroidism 0.5562009517757402 1.48272070283071 0.1381486318039 1.0 0.3363441324805867 14 P35670,P03886,P03915,P21964,P00403 5 +Hepatic cysts 0.5817984835440266 1.4823608992925248 0.1382442920868036 1.0 0.3363441324805867 4 O75665 1 +Abnormal lung lobation 0.5561226092441828 1.4822396601889276 0.1382765371917453 1.0 0.3363441324805867 14 P21964,O60566,Q14739,Q9UHX1 4 +Sea blue histiocytosis 0.5610856781400564 1.4820815218698629 0.1383186048287135 1.0 0.3363441324805867 3 O15118 1 +Amyloidosis 0.5606047080905993 1.4793490925332804 0.1390470384228257 1.0 0.3372079926722701 3 P05067 1 +Hypoplastic helices 0.5401694420099433 1.4788286688527756 0.1391861115587234 1.0 0.3372079926722701 2 P08754 1 +Cystinuria 0.5401694420099403 1.478828668852758 0.139186111558728 1.0 0.3372079926722701 2 Q4J6C6 1 +Intellectual disability borderline 0.540169442009935 1.4788286688527266 0.1391861115587365 1.0 0.3372079926722701 2 Q7Z392 1 +Abnormality of the tongue 0.3497577862773543 1.4770152695813925 0.1396715442059781 1.0 0.3378334999821509 103 P21912,P40855,Q05086,O75665,Q9BQT8,Q96A33,Q7LGA3,Q96J42,P07196,Q9Y4P3,Q13510,Q96RL7,O43924,O75844,Q6NUK1,Q9NUN5,O75431,Q96S52,O75381 19 +Abnormal posterior segment imaging 0.5806600822618572 1.4760812662778886 0.1399220773621303 1.0 0.3380018296142496 4 Q96S66 1 +Myoclonic spasms 0.5967593446132561 1.47596278652844 0.1399538825746502 1.0 0.3380018296142496 9 P00846,Q10713 2 +Occipital meningocele 0.5958441310237972 1.475528929426177 0.1400703965190601 1.0 0.3381060173702615 5 P21964 1 +Abnormality of the dorsal column of the spinal cord 0.5593220338983012 1.472059212897443 0.1410048883925858 1.0 0.3401437320229812 3 Q8WVX9,P54886 2 +Abnormal pericardium morphology 0.5794138229892318 1.471570240133609 0.1411369668545246 1.0 0.3401437320229812 12 P04062,P47985,Q9NZ08,Q14108,P14174,P02545,Q8NBM4 7 +Oval face 0.6058230921660704 1.4710550284774098 0.1412762356749661 1.0 0.3401437320229812 7 Q9UHX1 1 +Distal arthrogryposis 0.5949546567742574 1.470714626272676 0.1413683090154682 1.0 0.3401437320229812 5 Q96A33 1 +Abnormal cardiac ventricular function 0.4959048367158168 1.4682379434624673 0.1420396008955422 1.0 0.3412505114320431 19 P21912,O95235,P03886,P09622,P03915,O75844,P12235,P00403 8 +Abnormal saccadic eye movements 0.4364981149126071 1.467871866517029 0.1421390314640374 1.0 0.3413114418896739 25 P04062,Q8IV08,Q96RL7,O95140,O14773,Q9NQ11,O43819,Q10713 8 +Limited wrist movement 0.5942043799687 1.466652313397644 0.1424706613260493 1.0 0.3419295871825184 5 O75844 1 +Mild short stature 0.5786921860821598 1.4652186184777067 0.1428612814749246 1.0 0.3425102939835862 4 Q14739,Q8WVQ1 2 +Episodic tachypnea 0.5892316215115966 1.4634932801178764 0.1433324510574436 1.0 0.3427165453819195 10 O43924,O75665,Q10713,P22695 4 +Preaxial hand polydactyly 0.5831658512568305 1.4602310634011788 0.1442265807768545 1.0 0.3433807065407212 11 O95202,Q9UHX1,Q96J42 3 +Talipes equinovarus 0.3536378782112353 1.4600818197106202 0.1442675885119002 1.0 0.3433807065407212 80 O75665,Q9HC21,Q96A33,Q969X5,P16435,Q8TAA9,O95202,Q15907,Q8WVQ1,P21964,Q9NR77,Q8NCH0,O75845,Q9UM00,Q9H9E3,Q15125,Q96L58,Q9NWM8,Q15392,Q8NBU5 20 +Upgaze palsy 0.5925031593566765 1.4574364139704143 0.1449959515679508 1.0 0.3447581758643537 5 Q96RL7 1 +Short lower limbs 0.556151680807095 1.4540230730755186 0.1459399093783622 1.0 0.346644898152316 3 Q8N6S5 1 +Abnormal brain lactate level by mrs 0.5818364678682757 1.4526207698956857 0.1463290760552185 1.0 0.3473902021960056 11 P21912,P03886,P03915,O43819,P00403 5 +Shoulder girdle muscle weakness 0.581763868202805 1.4522050313300128 0.1464446041393681 1.0 0.3474854458672545 11 P12235,P07602 2 +Short sternum 0.5557809750081208 1.451912478912688 0.1465259422923051 1.0 0.347499506990706 3 O60566 1 +Aplasia hypoplasia involving bones of the feet 0.3508661258151649 1.4506630560166267 0.1468737075369721 1.0 0.3481450845320821 68 Q9Y2B2,O75665,P13073,Q9H9E3,O95202,Q96A33,P00813,Q7LGA3,Q96S52,Q8WVQ1,Q5JRA6,Q9NX62,Q13510,Q9UHX1 14 +Supraventricular arrhythmia 0.5021310936694279 1.4484742141365403 0.1474844724420272 1.0 0.3494130843253786 18 P50402,P00846,P12235 3 +Abnormal renal tubule morphology 0.4209085864143326 1.4470151377250562 0.1478926839087342 1.0 0.3500963268684676 28 Q9Y276,P00846,Q9Y4P3,P03886,P03915,O43819,P23786 7 +Microdontia 0.41800869223455 1.4458996349352018 0.1482053543503334 1.0 0.3504003452264425 30 Q9Y2B2,Q96A33,Q7LGA3,Q9Y4P3,Q6NUK1,Q9UM00 6 +Aplasia hypoplasia involving the pelvis 0.5614780432398244 1.438145782032274 0.1503926949636573 1.0 0.3548435936469704 13 Q96HY6,O75431,O95202,Q96L58,Q8WVQ1 5 +Talipes calcaneovalgus 0.5884383784748825 1.4353900987839647 0.1511759658695364 1.0 0.3565091354794389 5 P07196 1 +Temperature instability 0.5892364617976779 1.4341948309521102 0.1515166717444178 1.0 0.3570481726192752 9 Q9HC21,Q9NZJ7,P07602 3 +Pulmonary embolism 0.58791164316875 1.4325305309284726 0.151992046945526 1.0 0.35770140568181 5 Q9NZ08 1 +Abnormal lower limb bone morphology 0.3321303293488181 1.431902982463747 0.1521715885836281 1.0 0.357941133329943 171 Q9Y2B2,Q96HY6,P04062,O75665,Q96A33,Q7LGA3,Q96J42,O75787,Q969X5,Q9UHX1,Q10713,P13073,P16435,O95202,P00813,Q8WVQ1,P07602,Q9NX62,Q14118,P21964,Q13510,Q9NZJ7,O75845,Q14739,O43924,O75844,Q8N6S5,Q9H9E3,Q8NAT1,O75431,Q15125,Q96L58,Q96S52,O00116,Q5JRA6,Q15392 36 +Paranoia 0.60273792854674 1.4299174316618468 0.152740718337053 1.0 0.3583651884404992 6 Q96RL7,Q96DF8 2 +Gingivitis 0.551431911163053 1.4271260185883383 0.1535435740800304 1.0 0.3595639392576589 3 P53634,P40763 2 +Phenotypic variability 0.3446118998692968 1.4270559584086828 0.1535637657246251 1.0 0.3595639392576589 106 P21912,P02545,P11166,Q8WWY3,Q9H061,P07196,O95470,Q9Y276,Q9NWS8,P00374,P00846,Q8WVQ1,P07602,Q8NI60,Q969G3,Q14118,P09622,Q13510,Q9NZJ7,Q9NR77,O60313,Q70HW3,P17900,O60762,Q53H12,P03886,P03915,P00403,Q6P4A7,Q15125,P33993,P52732,O95140,Q9Y375,Q9UBB4 35 +Constriction of peripheral visual field 0.4711165073471594 1.4243974074801793 0.1543314642829116 1.0 0.3609946129013487 21 P40855,O60313,P00846,Q8TC12,Q9H061 5 +Microretrognathia 0.4804596838107438 1.423851756279171 0.1544893897498309 1.0 0.3609948731207132 20 O75665,P53007,Q9BUB7,Q15125,Q8WVQ1,Q8NCH0,Q9UHX1,Q15738 8 +Ambiguous genitalia 0.4309270762375323 1.4215402641416672 0.1551597568335889 1.0 0.3620301786626106 25 P16435,Q8TAA9,P53701,Q96J42,O75845,O60566,Q15392,Q9NX14 8 +Abnormal skin morphology of the palm 0.3471761258803806 1.4215152804924895 0.1551670145092569 1.0 0.3620301786626106 100 Q9Y2B2,P21912,P40855,O75665,O95721,O75431,O95202,Q96S52,Q8NCH0,Q15907,O75381,Q9Y2U8,P42167,P16615,Q96I36,Q9UHX1,Q6NUK1,P09493 18 +Cerebral hamartoma 0.5849160398515636 1.416256311609485 0.1567004740820794 1.0 0.3645006484453417 5 O43924,O75665 2 +Abnormal lung development 0.3760408336444882 1.4146599028389837 0.1571682361638411 1.0 0.3650096366800132 48 O75665,Q8TAA9,Q96DF8,O95202,Q96L58,O96000,O60566,Q14739,Q15645,O75844,P21964,Q9UHX1,Q6NUK1 13 +Abnormal myocardium morphology 0.3327272840624993 1.414631251093838 0.1571766410392816 1.0 0.3650096366800132 189 Q8N183,P21912,P04062,Q86Y39,P40855,Q9NZ08,O96000,P50416,O76024,Q9BT22,Q9NX14,Q9H061,O43819,Q9Y6M9,P23786,Q5XKP0,O43676,Q9NVI7,Q9BUB7,Q96CU9,Q9P0J0,P00846,Q9Y4P3,Q7KZN9,P42167,Q14108,P12235,Q13423,Q96RL7,P53701,O60313,Q53H12,P03886,P13473,Q96I36,P03915,P00403,Q8NBM4,Q96DA6,Q9NPL8,O75381,P50402,Q8IUX1,Q8N5K1,Q9Y375,P09493 46 +Impaired antigen specific response 0.5805380849028174 1.41442845888949 0.1572361390646324 1.0 0.3650096366800132 10 P60033,P00813 2 +Retinal degeneration 0.3465869137914191 1.4057594431242202 0.159795568941552 1.0 0.3694621082201061 57 P04062,Q9UG56,Q7LGA3,O60313,P50897,O14773,Q96S66,Q8TC12,P51648,Q96HR9,Q13510,Q9NWW5,Q10713 13 +Decreased circulating progesterone 0.5979678554448498 1.40448161116739 0.1601754837361579 1.0 0.3695779479552877 6 P49770,P16435 2 +Abnormal circulating progesterone level 0.5979678554448498 1.40448161116739 0.1601754837361579 1.0 0.3695779479552877 6 P49770,P16435 2 +Personality changes 0.4868135458571055 1.403818328088709 0.1603729547803607 1.0 0.3695779479552877 19 P04062,P35670,Q96RL7,P49770,P03886,P03915,P00403 7 +Gowers sign 0.5422285209920378 1.3966427076243928 0.1625210407318669 1.0 0.3740744034427785 14 P07196,Q13510,Q8NAT1,Q14118 4 +Resting tremor 0.4673509278343855 1.3962882414979405 0.1626277132464553 1.0 0.3741330517422197 21 Q9NZJ7,Q96RL7,Q9H6K4,P07602,O75787,Q9NQ11,P12235 7 +Abnormal nasal mucosa morphology 0.5653007828111376 1.3910603670178512 0.1642071218471157 1.0 0.3768259051152934 4 O75665,Q03519 2 +Young adult onset 0.5654612868287452 1.39025676216445 0.164450922458152 1.0 0.3770098759637635 12 Q9NQ11,Q9NZJ7,Q9H0U3,P07602 4 +Hemivertebrae 0.5406597326992402 1.3869437640464757 0.1654589114832108 1.0 0.3787554218155168 14 P16435,Q9Y619,Q15125,Q9UHX1,Q9UM00 5 +Cherry red spot of the macula 0.5797013889759617 1.3810675194229471 0.1672582013070267 1.0 0.3820316985380163 9 Q9NZJ7,P17900,P07602,Q13510,P10619 5 +Biliary cirrhosis 0.5935563117817727 1.3809163554703268 0.1673046804795392 1.0 0.3820316985380163 6 Q14739,P09601 2 +Protrusio acetabuli 0.543249561659838 1.3803705811707874 0.1674725733306248 1.0 0.3822256651349773 3 O75718,Q96AY3 2 +Abnormality of glycolipid metabolism 0.5842050999843809 1.3792054563459548 0.1678314162406393 1.0 0.3828550326915179 8 Q9NZJ7,O43681,P07602 3 +Cessation of head growth 0.587773120737619 1.3734845091252412 0.1696017737359048 1.0 0.3861049313330709 7 P49770,Q05086 2 +Respiratory insufficiency 0.3299582357566949 1.371202872247164 0.1703117230860149 1.0 0.3867897584920438 184 Q8N183,O75665,Q86Y39,P40855,O96000,Q969X5,O76024,Q9BT22,Q9NX14,O43819,Q9Y6M9,P23786,Q5XKP0,O43676,P53007,Q9BUB7,Q96CU9,Q8WVQ1,P07602,Q14118,Q13510,Q9HCC0,Q96AA3,P12235,Q9NZJ7,Q9NR77,Q9BYC5,P53701,Q70HW3,Q53H12,Q14739,P03886,Q96I36,P13473,Q6NUK1,Q96L58,O95140,Q9NPL8,O75381,P50402,Q8IUX1,Q68CQ7,Q8N5K1,Q8NBU5,Q15165,Q9Y375 46 +Hemiparesis 0.472933499993099 1.3690296306213 0.1709900129451553 1.0 0.3876107722058462 20 O60313,Q9NZ08,P03886,P03915,P00403,Q8NBM4 6 +Abnormal circulating glutamine family amino acid concentration 0.5908737470352811 1.3665680780103018 0.1717607286629925 1.0 0.388930436205931 6 P20674 1 +Megaloblastic anemia 0.5761063255083716 1.36098506122448 0.1735184104443441 1.0 0.3921934303236659 9 P00374,Q9NUN5 2 +Abnormal macular morphology 0.4133537110682116 1.36090982432294 0.1735421884613617 1.0 0.3921934303236659 26 P04062,P50897,P51648,Q96HR9,Q13510,Q9UM00 6 +Bifid scrotum 0.5893508860400931 1.358416576813894 0.1743315371951734 1.0 0.3935912412520134 6 P16435 1 +Nyctalopia 0.4035590106432463 1.357243775206522 0.1747037657290195 1.0 0.3941953790193813 33 O75665,P40855,Q9H9E3,O95140,O75381,Q96S66,Q8TC12,Q96HR9,Q10713 9 +Progressive spastic paraplegia 0.4051071558704247 1.3570346001080844 0.174770216869921 1.0 0.3941953790193813 32 O75298,Q96CU9,Q9P0J0,P00846,Q7KZN9,Q9NQ11,O00400 7 +Ichthyosis 0.3963866735226768 1.3561596261612716 0.1750483847791299 1.0 0.3944366538201618 37 Q9Y2B2,O95721,P40855,P04062,O95470,Q9BTV4,Q15125,O75381,P56589,P50402,Q15800,P51648,Q15738 13 +Glaucoma 0.3422415879796721 1.3512582817297671 0.1766127107723227 1.0 0.3973028153424525 100 O75665,P40855,Q8WWY3,O76024,Q9Y4P3,Q8WVQ1,O60566,Q14118,P21964,P12235,Q9BYC5,P53701,Q86XL3,Q8NCH0,Q53H12,Q8NAT1,Q15125,Q96L58,O75381,Q8N5K1,Q96HR9 21 +Recurrent pharyngitis 0.5379894798363413 1.3502336955993004 0.1769410329434477 1.0 0.3977289169772718 3 P01889,O15460 2 +Retinal vascular tortuosity 0.4962627008120072 1.3491807509593436 0.1772789159929233 1.0 0.3981000218788454 17 P00846,Q9Y4P3,P03886,P03915,P21964 5 +Abnormal cns myelination 0.3233641127538554 1.3476078230892106 0.1777845530847273 1.0 0.3990410231926076 149 Q8N183,Q9Y2B2,Q86Y39,P21912,P40855,Q8TB36,Q7LGA3,O96000,O75787,Q9NX14,O43819,Q9Y584,Q9Y6M9,O43681,O43676,Q5T8D3,Q96CU9,Q9P0J0,P07602,Q7KZN9,Q9H490,P49770,P51648,Q14118,P00387,Q5BJH7,O95169,Q9NZJ7,P51572,P03886,Q96I36,Q96S52,Q9NPL8,Q8IUX1,O00400,Q9Y375 36 +Severe global developmental delay 0.342063504991451 1.3396407847048006 0.1803621575622283 1.0 0.4034508844887126 68 P40855,Q9HC21,Q96A33,Q7LGA3,P00846,Q96S52,O75381,Q9H490,O60566,P00387,Q9BT22,Q14118,P03886 13 +Telangiectasia 0.3923520164682708 1.336155964100869 0.1814983010059609 1.0 0.4054019248838915 38 Q9Y2B2,P21912,Q8IZA0,P00846,Q14739,P03886,Q96JJ3,Q8N6S5 8 +Bruising susceptibility 0.4006418155260873 1.330480016099007 0.1833601663497475 1.0 0.4084532141536321 33 P35670,P49257,Q9NWM8,Q8NCH0,Q13126,Q14108 6 +Abnormality of carpal bone ossification 0.5841174939885633 1.3303705818986216 0.1833962022751443 1.0 0.4084532141536321 6 Q8WVQ1,Q15125 2 +Abnormality of the nasal dorsum 0.3436849720026244 1.3295330606923226 0.1836721659738596 1.0 0.4088702129505048 56 Q9Y2B2,O95721,O75431,O95202,Q15125,Q96J42,Q8WVQ1,O60566,O75844,Q6NUK1 10 +Distal joint laxity 0.5138767163307172 1.3239563190332322 0.1855175521594079 1.0 0.4115863651182242 2 Q02809 1 +Abnormal brainstem morphology 0.3405472215308102 1.321970601937943 0.1861779404602843 1.0 0.41214008058176 99 Q8N183,Q86Y39,O96000,Q9NX14,O43819,Q9Y6M9,Q10713,O43676,Q96CU9,Q969G3,Q14118,Q6ZXV5,O60313,P03886,Q9Y320,Q96DA6,Q96S52,Q9NPL8,Q8IUX1,Q9Y375 20 +Endocarditis 0.5812827109950924 1.3151582462648184 0.1884567244879493 1.0 0.4160842560457722 6 Q9NZ08,Q8NBM4 2 +Abnormal bleeding 0.3332684083759674 1.3146896789593516 0.1886142166816566 1.0 0.4160842560457722 112 P21912,P04062,Q4KMQ2,P49257,Q9NZ08,P05067,O76024,Q9UHX1,P23786,Q9UJS0,Q14108,Q969G3,P21964,Q96AA3,Q6ZXV5,P35670,P60033,Q8NCH0,Q14739,Q13126,O75844,Q8N6S5,Q8NBM4,Q9NUN5,Q96L58,Q9NWM8,Q8N5K1,Q96JJ3,P11117 29 +Intrauterine growth retardation 0.3274911793809602 1.3146472734112735 0.1886284745832505 1.0 0.4160842560457722 204 Q8N183,P21912,P04062,Q86Y39,Q9Y375,Q9BRT2,Q96RT7,O96000,P37268,Q9BT22,Q9NX14,Q9Y584,Q9Y6M9,Q9UHX1,O43676,Q9Y276,Q9BUB7,O95202,Q96CU9,Q9UJS0,Q8WVQ1,O60566,Q969G3,P21964,Q5BJH7,P51572,Q9BYC5,O75845,O75027,Q15645,P03886,O43924,O75844,Q8N6S5,Q15738,Q6NUK1,O75880,Q9H9E3,Q6P4A7,Q9NUN5,Q96L58,Q96DA6,Q9NPL8,Q8IUX1,Q15392,Q9Y2U8 46 +Scarring 0.3971009641238995 1.3126795794308572 0.1892909414427672 1.0 0.4169467773270896 34 O75665,Q15125,Q96L58,Q9NWM8,Q8NCH0,Q96HR9,Q9Y2U8 7 +Cranial asymmetry 0.5802069263106611 1.309381586617672 0.1904051255818966 1.0 0.4184206579141904 6 P40855 1 +Increased bone mineral density 0.4175157348746049 1.3093551141291373 0.1904140884648562 1.0 0.4184206579141904 25 P04062,Q15125,Q9Y4P3,Q14739,Q14108,Q15043,Q13126,Q15392,Q9Y2U8 9 +Upper limb muscle weakness 0.4023385729920555 1.3062836393489394 0.1914561187383754 1.0 0.4203095736762429 30 Q9BTV4,P00846,O95140,Q969X5,P50402,Q969G3,P50336,P07196 8 +Lower limb undergrowth 0.5497722621159676 1.304588977357023 0.1920328436169094 1.0 0.420646910668979 4 Q8N6S5 1 +Rhizomelia 0.5507455543682345 1.3039905053763676 0.1922368196497887 1.0 0.420820553418635 12 Q15392,O00116,Q14739,Q15125 4 +Narrow forehead 0.3598300466899644 1.3004422020462578 0.193449453646505 1.0 0.4230731288102017 50 Q9Y5U9,Q96A33,Q9BYC5,Q7LGA3,O75845,O75787,O43292,Q9UHX1,Q9UM00 9 +Pericarditis 0.5781661678786436 1.298417886385711 0.194143776127099 1.0 0.4239208415205288 6 Q9NZ08,Q8NBM4 2 +Rigidity 0.3410726221724157 1.2982394796763432 0.1942050556531762 1.0 0.4239208415205288 56 Q9NZJ7,Q96CU9,Q9H6K4,P00846,P07602,O75787,Q9NQ11,Q15392,Q8NBU5,P12235,O43681 11 +Abnormal abdomen morphology 0.3250075042474177 1.2970262394684962 0.1946221586088472 1.0 0.4246301642374849 230 Q8N183,Q96HY6,Q86Y39,P04062,P28288,P54802,P40855,Q15067,Q9HC21,Q96A33,Q9NZ08,O96000,O95235,P56589,P50416,O75787,Q9BT22,Q9NX14,P14174,Q9Y6M9,P23786,Q10713,P53007,O43676,Q9NWS8,Q9NVI7,Q9BUB7,P00374,P00813,Q9UJS0,P09601,Q01130,P07602,P00846,Q96CU9,O60566,Q14108,P09622,P21964,Q13510,Q96AA3,P56556,Q9NZJ7,P20674,P35670,P60033,Q96RL7,O75845,O60762,P16278,Q6PGP7,Q14739,Q15645,P03886,Q9Y3E5,Q96I36,P03915,P10619,Q8N6S5,Q8NBM4,O75880,Q9H9E3,Q9Y619,P14927,O75431,O15118,Q96S52,Q9NPL8,O95140,O75381,Q8IUX1,Q15392,Q15904,Q9Y375,Q9H0U3 75 +Premature rupture of membranes 0.5777468937198519 1.2961645288066677 0.1949188072548886 1.0 0.4249741116600736 6 O75844,Q9Y487 2 +Aplasia hypoplasia of the nipples 0.4799651898198567 1.2944099325775649 0.1955238615934744 1.0 0.4259924133440805 18 Q9Y2B2,O95202,Q96A33 3 +Abnormality of the nasal cavity 0.5086181711948697 1.292790834655217 0.1960834111964611 1.0 0.4269605810143329 2 Q92990 1 +Abnormal larynx morphology 0.4032588571324635 1.2923664029597084 0.1962302859191094 1.0 0.4269605810143329 28 Q96HY6,P16435,Q9NZJ7,P21964,P07602,Q13510,Q9UHX1 7 +Hydrocele testis 0.5728005533904252 1.2920527975740468 0.1963388609308531 1.0 0.4269605810143329 7 Q9UBX3 1 +Arthralgia 0.3876335542201851 1.290629007804551 0.1968323523581814 1.0 0.4275111362865803 38 Q96HY6,P35670,P60033,Q03252,O95140,Q9NZ08,Q01130,Q9Y4P3,Q13510,Q15800,Q2M1P5,P14174,Q8NFV4,Q9Y2U8,P02545,Q8NBM4 16 +Diffuse mesangial sclerosis 0.4532476973514008 1.2905194513639642 0.1968703626736379 1.0 0.4275111362865803 21 P00813,Q96D53 2 +Abnormality of the ureter 0.3373890251448307 1.2895972441000607 0.1971905330874066 1.0 0.4279596651124595 66 Q9Y2B2,P21912,P16435,Q8TAA9,Q7LGA3,Q9Y4P3,Q96J42,O76024,P23786,O75844,P21964,Q9UHX1 12 +Aplasia hypoplasia of the skin 0.3351562417155512 1.2893896490206016 0.1972626581377743 1.0 0.4279596651124595 61 O75431,O95202,Q9NWM8,P53701,Q96L58,Q15125,Q8NCH0,Q13126,Q15392,Q9NX14,O75844,Q8N6S5,Q9Y2U8,Q6ZXV5 14 +Laryngomalacia 0.5366278902559337 1.2885672805338306 0.1975485645422028 1.0 0.4283782519578685 13 P16435,Q9NZJ7,P07602,P36543,Q2M1P5,P21964 6 +Erythroderma 0.5675664018816592 1.2874019696969132 0.1979542181572684 1.0 0.4290559911894134 8 P00813 1 +Contractures of the joints of the upper limbs 0.3390398727399636 1.2859549911834651 0.1984587701164939 1.0 0.4295434535917351 72 Q9Y2B2,P16435,Q8IZA0,Q9BUB7,Q96L58,Q7LGA3,Q8WVQ1,P37268,Q969X5,P50402,P42892,Q15392,O75844,P23786,P07196 15 +Emotional lability 0.335289191317156 1.2849615610656415 0.1988057167258181 1.0 0.4298905409068841 62 Q8N183,Q9Y276,Q9NZJ7,Q96RL7,Q96CU9,Q9P0J0,P07602,Q7KZN9,P49770,Q969G3,Q68CQ7,Q15165,O43681 13 +Retinal arteriolar tortuosity 0.5472765206759681 1.2835864072896228 0.1992867082776801 1.0 0.4307284951892824 12 P21964,P00846 2 +Renal hypoplasia 0.393916584619726 1.2830992467049187 0.1994573076676737 1.0 0.4308951119234134 34 Q9Y4P3,O43924,Q96I36,P21964,Q9UHX1 5 +Wide cranial sutures 0.5710595843588668 1.2825581703415272 0.1996469129270393 1.0 0.4309057369034721 7 O75531,O75844,O75718,P02545 4 +Hypoplasia of the iris 0.5747794331869664 1.2802079172428014 0.2004720222131428 1.0 0.4322709599988327 6 Q7LGA3 1 +Paraplegia paraparesis 0.3400704345972325 1.2799794332974368 0.2005523692076838 1.0 0.4322709599988327 82 Q8N183,Q5XKP0,P21912,O75298,Q96L58,Q96CU9,Q9H6K4,P00846,O60313,Q9P0J0,O75787,Q7KZN9,Q9NQ11,Q6DKK2,O00400,Q13510,Q15041 17 +Abnormality of the biliary system 0.3258050828985164 1.2796473857638797 0.2006691765114532 1.0 0.4322709599988327 119 P04062,P28288,P40855,Q9Y5U9,Q96A33,O75787,P14174,O43681,Q10713,Q5XKP0,Q9Y276,O95202,P00374,P09601,Q9Y4P3,P07602,Q14108,P22830,P21964,Q13510,Q9NZJ7,P35670,O75845,Q14739,Q9NUN5,O15118,O75381 27 +Abnormal thyroid stimulating hormone level 0.5062810400233819 1.2789217849602388 0.2009246003155622 1.0 0.4324430444904768 2 P10644 1 +Type i transferrin isoform profile 0.5509556379080516 1.2746758972357273 0.2024239813821891 1.0 0.4345433510732255 11 Q2TAA5,O60762,Q9BT22,P51571,Q9H0U3 5 +Vocal cord paralysis 0.4684644892080941 1.2729035037494942 0.2030522858011001 1.0 0.435598199707388 19 P21912,Q9BTV4,Q8TB36,Q9NR77,O95140,P50402,Q02978 7 +Neuronal loss in central nervous system 0.545287344964667 1.2718757300893313 0.2034172762744426 1.0 0.4356823137645302 12 O43819,O15118,Q9NZJ7,P07602 4 +Purpura 0.4323300761789641 1.2717282442922186 0.2034696916712823 1.0 0.4356823137645302 23 P60033,P21964,Q8NCH0 3 +Hyperthyroidism 0.5553078932396529 1.2710842913321605 0.2036986631363593 1.0 0.4357676136176154 10 P21964 1 +Vaginal neoplasm 0.5431516054204464 1.2675838221751785 0.2049466122439687 1.0 0.437421949615659 4 O60566 1 +Dysmetria 0.3332884304862132 1.26610104541862 0.205476908393142 1.0 0.4379806793197724 61 Q8N183,Q96TA2,O75787,O14773,Q6DKK2,Q8NFV4,Q10713,Q5T8D3,Q96BR5,Q9Y4P3,Q8N2K0,Q6PJG6,Q5JRX3,O60313,O75027,O43292,Q9Y3E5,Q12768,Q6P4A7,O75503,Q8IV08,Q9NPL8,Q9UBB4 23 +Abnormality of the leydig cells 0.5227207067711537 1.262435111970743 0.2067922614190811 1.0 0.4401379864291574 3 Q13423 1 +Abnormality of the middle ear 0.3138584954044288 1.261998648553418 0.2069492726737103 1.0 0.4402688127795278 132 Q9Y2B2,P21912,O75665,Q96A33,Q7LGA3,O95202,P00813,Q9Y4P3,P21964,O00165,P60033,Q03519,O75845,O43924,O75844,Q6NUK1,Q96L58,Q9NWM8,Q8N5M9,Q96HR9,Q96JJ3,Q9H0U3 22 +Decreased number of peripheral myelinated nerve fibers 0.4959631753508154 1.2606903996940686 0.2074204141666749 1.0 0.4409122151305849 16 Q9NR77,Q96RL7,O95140,O15269,P07196 5 +Aplasia hypoplasia involving bones of the lower limbs 0.3382535051589086 1.26012438178687 0.2076244959833879 1.0 0.4409222852420917 90 Q9Y2B2,Q96HY6,O75665,Q96A33,Q7LGA3,Q9UHX1,P13073,O95202,P00813,Q8WVQ1,Q9NX62,Q13510,Q8N6S5,Q9H9E3,O75431,Q96L58,Q96S52,O00116,Q5JRA6 19 +Renal agenesis 0.3344641815120176 1.2586491630675545 0.2081570810963064 1.0 0.4418184383656288 57 O95169,O75665,P16435,Q9NUN5,Q8TAA9,Q7LGA3,Q86XL3,Q15392,O43924,O43819,Q9UHX1,Q15738 12 +Progressive spasticity 0.4829444431542313 1.2583243260649466 0.2082744870633703 1.0 0.4418641051510178 17 Q9NZJ7,O60313,P07602,Q9NQ11,O43681 5 +Abnormal endocrine physiology 0.5703421948615305 1.2563221222705785 0.2089992043645798 1.0 0.4429937137589623 6 P16435,Q13423 2 +Venous insufficiency 0.5544672438825331 1.2498307003848534 0.2113613987175453 1.0 0.4463580775849903 5 P21964 1 +Varicose veins 0.5544672438825331 1.2498307003848534 0.2113613987175453 1.0 0.4463580775849903 5 P21964 1 +Shallow orbits 0.5560161151506886 1.2482926370786993 0.2119239096036624 1.0 0.4468964411985288 9 O75844 1 +Aplasia hypoplasia affecting the eye 0.334324132730119 1.2480731830701448 0.2120042579123229 1.0 0.4468964411985288 102 P21912,Q7LGA3,Q96J42,Q96RT7,P37268,Q9UHX1,P07196,O95721,Q9NVI7,O95202,Q9Y4P3,O60566,Q14118,P21964,O43924,Q96I36,Q6NUK1,Q8NAT1,Q15125 19 +Abnormality of skull ossification 0.5297715867658372 1.2470504736095926 0.2123789910471496 1.0 0.4474816601487268 13 P54802,O75718,Q9HC21,Q14739,O75844,Q93063,Q6NUK1,P02545 8 +Easy fatigability 0.4380803920871491 1.2442954753654674 0.2133908356933387 1.0 0.4487927753879072 22 P21912,Q8IUX1,P12235,Q9NWM8 4 +Abnormal larynx physiology 0.5055803665472585 1.2431559491732855 0.2138103718396269 1.0 0.4490602522502283 15 Q15165,Q68CQ7 2 +Joint swelling 0.5674113454403636 1.240529108213787 0.2147797546754959 1.0 0.4502753000658258 6 Q13510,P35670 2 +Pharyngitis 0.5381467407190867 1.239561762438962 0.2151375311197001 1.0 0.4505437301371259 4 P01889,P61011,O15460 3 +Progressive neurologic deterioration 0.4373180164045279 1.238388186270075 0.2155721589512147 1.0 0.4509722282761682 22 P21912,P54802,P04062,Q5XKP0,Q9NZJ7,P56556,Q9NPL8,P07602,O43681,Q10713 10 +Wide anterior fontanel 0.3991954131733813 1.2383089588259777 0.2156015231971351 1.0 0.4509722282761682 26 Q9H9E3,P16435,P40855,P20674,Q15125,O75381,P56589,Q2M1P5,Q6NUK1 9 +Myoclonic seizure 0.3299329891034954 1.237478728077567 0.2159094067853242 1.0 0.4512065970370857 59 P21912,P04062,Q9Y5U9,P11166,Q01105,Q5XKP0,P00846,Q8IYI6,P07602,O60566,Q13510,Q96N66,Q9NZJ7,Q6PJG6,O60762,P16278,Q9HA77,O43292,Q9Y4W6,Q9Y3E5,P03886,P03915,Q9Y619,O75503 24 +Chronic otitis media 0.3969987241327111 1.2371306572185656 0.2160385798737427 1.0 0.4512718839792414 28 Q03519,O95202,P60033,Q9Y4P3,P21964 5 +Overlapping toe 0.4366385433543573 1.2331216784211962 0.2175303705864513 1.0 0.4529805977022642 22 Q96A33,Q9UHX1,Q15907,Q15125 4 +Preaxial polydactyly 0.4792171842964657 1.232811379670079 0.2176461446964794 1.0 0.4529870979048678 17 O95202,O43924,Q9UHX1,Q96J42 4 +Long toe 0.557616026045164 1.232266340816501 0.2178496088248267 1.0 0.453205867929933 8 O60762,Q9UHX1,P23786,Q15738 4 +Abnormality of the gingiva 0.3641211015953942 1.231072655487286 0.2182956915947367 1.0 0.4537241979560427 46 Q9Y5U9,P49257,Q96S52,Q9Y4P3,O75845,Q8N766,Q14739,Q14108,Q5JRA6,Q15392,Q96JJ3,Q9UM00 12 +Multiple rows of eyelashes 0.5166569257743996 1.2274512289144397 0.2196530419001214 1.0 0.4556926363612064 3 Q9Y2Z4,O60716 2 +Neoplasm of the small intestine 0.5649445452144866 1.2272272119254055 0.2197372044259116 1.0 0.4556926363612064 6 P21912 1 +Ulnar claw 0.5354102060778629 1.224223869839648 0.2208677869213244 1.0 0.4576253426859097 4 Q9NR77,P07196 2 +Abnormality of the fetal cardiovascular system 0.5596717858716178 1.2203355401820706 0.2223377022379165 1.0 0.4590410381868093 7 Q9Y2B2,P16435,Q12768 3 +Retinal dysplasia 0.5414438923937087 1.2194765469901585 0.2226633721344817 1.0 0.4590410381868093 11 Q8NAT1,O43505,P53701,Q14118,Q9NX14,O43924,Q10713 7 +Secondary microcephaly 0.334757292941544 1.2143102194104798 0.2246292846704547 1.0 0.4620945284649354 78 Q86Y39,Q05086,Q9HC21,P11166,Q9BT22,Q9NP72,Q9UHX1,Q5XKP0,O95721,Q5T8D3,P00374,Q96CU9,Q8N766,P49770,Q15043,Q9H2M9,Q9Y487,O60762,Q9NR50,Q9HA77,Q9Y3E5,O43464,P50897,P36543,O75208 25 +Abnormality of the larynx 0.3573445310733399 1.2131213907247702 0.22508341283144 1.0 0.4624094366149245 48 Q96HY6,P16435,Q9NZJ7,P21964,Q15165,P07602,Q68CQ7,Q13510,Q9UHX1 9 +Abnormal cornea morphology 0.3176147726293734 1.212777724939229 0.2252148139956691 1.0 0.4624732009322831 159 Q9Y2B2,O75665,P04062,P40855,Q7LGA3,Q9NZ08,Q96J42,Q8WWY3,Q9Y5Z9,Q2TAA5,Q9NVI7,O95202,Q9Y4P3,Q8N766,O60566,P51648,Q14118,P21964,Q13510,P12235,P35670,P53701,Q8NCH0,O75845,Q53H12,Q14739,O75844,Q6NUK1,Q8NBM4,Q8NAT1,Q15125,Q96L58,Q9NWM8,O75381,Q96HR9 35 +Oculomotor apraxia 0.3950857041837132 1.2109790033561496 0.2259034518936833 1.0 0.4633699759412867 27 Q9Y2B2,P04062,O96008,O14773,O43292,O43924,Q10713 7 +Unilateral renal agenesis 0.4426588821474374 1.2106533741642302 0.2260282790478602 1.0 0.4633699759412867 21 Q9NUN5,Q9UHX1,P16435,Q7LGA3 4 +Eeg with focal spike waves 0.5127087868521459 1.2046427735510667 0.2283412367161803 1.0 0.4661924762021086 3 Q14118 1 +Abnormality of the extraocular muscles 0.4937189599766458 1.204209095292622 0.2285087714430407 1.0 0.4662195236941071 2 P43243 1 +Thoracic hypoplasia 0.3909595308553356 1.20408471569584 0.2285568368109782 1.0 0.4662195236941071 30 Q96HY6,P16435,P04062,Q96A33,Q8WVQ1,Q14739,Q9UHX1,Q9UM00 8 +Elevated hepatic transaminase 0.331260157969311 1.2034260307435192 0.2288114996593471 1.0 0.466532473641713 102 O75665,P40855,P28288,Q15067,Q9Y5U9,O75787,P50416,P23786,Q10713,Q5XKP0,Q2TAA5,Q9Y276,P22695,Q9UJS0,P09622,Q13510,P12235,Q9H078,P20674,P35670,P60033,Q96RL7,Q8N511,O75845,Q14739,P08574,O75880,Q9H9E3,Q9Y619,O75431,Q96DA6,Q15904,P50336 33 +Muscle spasm 0.3281781771086995 1.2021864330914105 0.2292913044773419 1.0 0.4669267359586397 61 P07196,O75298,Q9NR77,Q9H6K4,P00846,O95140,Q68CQ7,P13473,Q15165,P23786,P05023,P12235 12 +Plantar hyperkeratosis 0.3832749892678318 1.1984826275981215 0.2307291821812753 1.0 0.469196854144447 35 Q9Y2B2,P21912,O75431,P42167,P16615,Q9Y2U8,P09493 7 +Motor deterioration 0.5592774425162388 1.1966376296447288 0.2314478268441009 1.0 0.4696220106110159 6 P21912,Q9NWW5 2 +Congenital onset 0.3227950710544071 1.196310860878642 0.2315752720000827 1.0 0.4696737910987594 116 O75665,Q9HC21,Q9Y5U9,Q7LGA3,P08670,Q96RT7,Q969X5,O43819,Q9UHX1,Q5XKP0,P46977,P07602,Q5BJH7,P12235,Q9NZJ7,P20674,Q96N66,Q9BYC5,O43924,P51571,Q6NUK1,Q15125 22 +Abnormal circulating acetylcarnitine concentration 0.5551100001862658 1.195358250429736 0.2319470900340152 1.0 0.4700141560583739 7 Q9NUN5 1 +Abnormal visual field test 0.5545567025907215 1.1923269566780756 0.2331330686123247 1.0 0.4717949847016216 7 P00846 1 +Renal salt wasting 0.5103450801218756 1.1909771637176718 0.2336625499186153 1.0 0.4720341074763784 3 Q13423 1 +Lipoma 0.5582140877751147 1.1908934718356314 0.2336954076531059 1.0 0.4720341074763784 6 P21912 1 +Spastic paraplegia 0.3351999687769548 1.1895614495035318 0.2342188053505671 1.0 0.4725395162239113 55 Q8N183,P04062,Q9Y619,O75298,Q12768,Q96CU9,Q9P0J0,P00846,O60313,O94905,Q9UI09,P11166,P56589,Q7KZN9,Q9NQ11,O00400,Q9H2M9,Q15041 18 +Abnormality of the amniotic fluid 0.3325791267858825 1.1874045912981503 0.2350680698581313 1.0 0.4736308115025226 93 Q9Y2B2,P04062,Q7LGA3,Q96J42,Q969X5,Q9BT22,P23786,Q9UHX1,P16435,Q9NVI7,Q9BUB7,O60566,P21964,Q9BYC5,Q70HW3,Q14739,Q96I36,O75844,Q6NUK1,Q9UM00,Q15125,Q96L58 22 +Axial dystonia 0.5096434833430709 1.1869195122507623 0.2352593700051066 1.0 0.4738090808494455 3 Q99720,P35637 2 +Headache 0.3319449939686347 1.1844496629185777 0.2362351110306662 1.0 0.4748192738537021 75 P21912,P04062,Q8TAA9,Q9NQZ5,Q8NBM4,P00846,Q9NZ08,O60313,P05067,Q96D53,P00387,Q969G3,P03886,P03915,P23786,P12235,P00403 17 +Brittle hair 0.4844595218566543 1.1843505864293264 0.236274311902624 1.0 0.4748192738537021 16 O75665,Q9Y276,Q9NVI7,Q9Y487,O75844,Q6NUK1 6 +Weakness due to upper motor neuron dysfunction 0.3137285614044011 1.1819897684913276 0.2372097606217553 1.0 0.4760528542001969 149 Q8N183,P21912,P04062,Q9NZ08,O75787,P50416,Q6DKK2,O43681,Q5XKP0,O75298,Q96CU9,Q9P0J0,P00846,P07602,Q7KZN9,Q969G3,Q13510,Q13423,Q9NZJ7,P51572,O60313,O94905,P17900,Q9NQ11,Q9HA77,P03886,P03915,Q15041,Q9UBX3,P00403,Q8NBM4,Q96L58,Q9H6K4,O00400 34 +Abnormal involuntary eye movements 0.3001641156084044 1.1814939218591185 0.2374065666128586 1.0 0.4760528542001969 304 Q8N183,P21912,P04062,Q86Y39,Q05086,P40855,O75665,Q7LGA3,Q9Y366,Q96RT7,O96000,O14773,Q8WWY3,O76024,Q9BT22,Q9NX14,Q9H061,O43819,Q6DKK2,Q9Y6M9,P07196,Q10713,Q5XKP0,O43676,P53007,Q9NVI7,O95202,Q96CU9,Q9P0J0,P00846,Q9Y4P3,Q15907,P07602,Q7KZN9,Q9H490,O60566,Q13510,P12235,Q9NZJ7,Q9NR77,O60313,Q53H12,Q9NQ11,O75027,O43292,P03886,O43924,P03915,Q6NUK1,Q9H9E3,O00400,Q15125,Q8IV08,Q9H6K4,Q96S52,Q9NPL8,O75381,Q8IUX1,Q15392,Q8N5K1,Q96HR9,Q9Y375 62 +Flat face 0.3925179463578282 1.180181660360897 0.2379279715620155 1.0 0.4766835186772902 26 P40855,Q15125,Q96L58,O75381,Q9NX62,Q9UM00 6 +Abnormal pupillary function 0.5519433232998812 1.1780043338186248 0.2387948784912725 1.0 0.4776613088228876 7 Q9NZJ7,P07602 2 +Adipose tissue loss 0.5427149496230524 1.1733133360826309 0.2406701762404701 1.0 0.4800901177991716 9 O75844 1 +Abnormal morphology of the abdominal musculature 0.5378384327190195 1.1711497979907772 0.2415385701834353 1.0 0.4805840585085212 10 Q8NCH0,Q6NUK1,Q8WVQ1 3 +Anophthalmia 0.5170199669591218 1.169605581264179 0.2421597302492215 1.0 0.4815776406055726 13 Q8NAT1,O43505,P53701,P52732,Q96J42,Q14118,Q2M1P5,Q9NX14 8 +Neoplasm of the tracheobronchial system 0.4878761320479218 1.1693765666486065 0.2422519468150428 1.0 0.4815776406055726 2 Q9UPY3 1 +Limb ataxia 0.3911507695742531 1.168259598468255 0.2427020667742656 1.0 0.4820565188344035 26 O75298,Q9NR77,Q8IV08,O14773,Q14108,P07196,Q10713 7 +Neuronal loss in basal ganglia 0.5249668047702396 1.1655977458279243 0.2437771196562306 1.0 0.4835664947808484 4 O95169,O43819 2 +Splenomegaly 0.3312280519434774 1.1628414299213243 0.2448938444468149 1.0 0.484167620875242 90 Q96HY6,P04062,P28288,Q96A33,Q9NZ08,Q9BT22,Q10713,P00813,P07602,Q14108,Q13510,P21964,Q9NZJ7,P35670,P60033,Q96RL7,Q14739,Q8NBM4,Q9H9E3,O15118,Q15392,Q9H0U3 22 +Osteolysis involving bones of the upper limbs 0.5449166139502164 1.1616900311615337 0.2453613964819565 1.0 0.4844153020517805 8 O75844 1 +Albuminuria 0.552162931087804 1.1581814796031542 0.2467899846151611 1.0 0.486237809843919 6 Q9Y5U9 1 +Extrapyramidal muscular rigidity 0.5519479087646629 1.1570183820766795 0.2472648502420524 1.0 0.486485332542543 6 Q9H6K4 1 +Hypoplastic vertebral bodies 0.5516248217632326 1.1552706562494497 0.2479796084466496 1.0 0.4866652622326071 6 P16278,Q14739,Q8TAA9 3 +Narrow vertebral interpedicular distance 0.5039302237964756 1.1538549549199018 0.2485596393395193 1.0 0.4873154077797406 3 Q96HY6 1 +Vertebral arch anomaly 0.5039302237964756 1.1538549549199018 0.2485596393395193 1.0 0.4873154077797406 3 Q96HY6 1 +Aplasia of the phalanges of the hand 0.4852468594800015 1.1536878867634384 0.2486281518424848 1.0 0.4873154077797406 2 P02545 1 +Abnormality of skin pigmentation 0.3078862740345387 1.1483707809702697 0.2508155305677002 1.0 0.4905990916488376 130 P21912,P04062,Q05086,Q7LGA3,Q96RT7,P16615,P07602,Q8N766,O60566,P51648,P21964,Q13423,Q8IZA0,Q9NZJ7,P53701,Q8TC12,Q14739,P03886,P03915,O75844,Q8N6S5,P00403,O75431,Q15125,Q9Y2U8 25 +Abnormal intraocular pressure 0.5464769812324047 1.148021408476659 0.2509597260915299 1.0 0.4906331853329528 7 P04439,Q12797,Q15043,Q8NCH0 4 +Paraplegia 0.3220730425855881 1.1467467811033611 0.2514862899942685 1.0 0.4908296587435786 58 Q8N183,P04062,P11166,P56589,O75298,Q96CU9,Q9P0J0,P00846,Q7KZN9,Q9H2M9,O60313,O94905,Q9NQ11,Q12768,Q15041,Q9Y619,Q96L58,Q9UI09,O00400 19 +Short nail 0.5356799970072627 1.1464112720185111 0.2516250208756574 1.0 0.4908925047396398 5 Q96L58,O75844,Q9Y487 3 +Abnormality of earlobe 0.3883951911511973 1.1442108129414148 0.2525362198688614 1.0 0.4922533422824506 26 P16435,P53701,Q7LGA3,Q8TC12,Q15392,P21964 6 +Abnormal ureter morphology 0.3964481323626702 1.1315605593252411 0.2578192295950796 1.0 0.4998994998322565 25 Q7LGA3,Q96J42,O76024,O75844,P23786 5 +Cerebellar atrophy 0.3092941181102471 1.130870826192435 0.2581094640146684 1.0 0.4998994998322565 143 O75787,O14773,Q9BT22,Q6DKK2,Q10713,P13073,Q5XKP0,Q9Y276,Q9NVI7,Q96CU9,Q96BR5,P46977,Q8N766,Q8N2K0,Q9H490,Q15043,Q8NI60,Q14108,P00387,Q5BJH7,P12235,Q9H078,P51572,O60313,O75845,O60762,Q9NQ11,Q9HA77,O43292,Q9Y320,O75503,Q8IV08,Q9H6K4,Q96S52,Q92643,O00400,Q9UBB4 37 +Eversion of lateral third of lower eyelids 0.4811568799298987 1.1292683991529202 0.2587846273709162 1.0 0.5008313998005804 2 P61978 1 +Long hallux 0.4995284407511873 1.1283564670606931 0.2591694049417787 1.0 0.5011160578234901 3 O60762 1 +Stenosis of the external auditory canal 0.5425990855461897 1.1267331644812026 0.2598553160254737 1.0 0.5020600822831794 7 O95202 1 +Photophobia 0.3687337551674579 1.124466884884524 0.2608150113064718 1.0 0.5034920704232182 39 O75665,Q9NZJ7,Q9NZ08,P07602,Q96S66,P51648,Q96HR9,Q8NBM4 8 +Cerebral hemorrhage 0.4979191379663427 1.120530868256561 0.2624876060428724 1.0 0.5056617427447978 14 P21912,P23786,Q969G3,P05067 4 +Congenital ichthyosiform erythroderma 0.5443911689627674 1.1161158672844311 0.2643725410243447 1.0 0.5085457340951344 6 P04062,Q15125 2 +Cardiovascular calcification 0.5367111868960635 1.115990680339256 0.2644261238914804 1.0 0.5085457340951344 8 O75844 1 +Abnormal corpus striatum morphology 0.4612503164169432 1.1094048885563002 0.2672555544242481 1.0 0.5129169490990984 17 Q96RL7,Q9NQ11,O43819,P00846 4 +Inappropriate behavior 0.4528029839812673 1.1037258129665166 0.2697120947353921 1.0 0.5169855792598532 18 Q05086,Q9NZJ7,P35670,Q96RL7,P07602 5 +Otitis media 0.3247512996641827 1.1011965668144557 0.2708111156017239 1.0 0.5181742101868739 56 Q03519,O95202,P60033,Q96A33,P00813,Q9Y4P3,Q8N5M9,P21964,Q9H0U3 9 +Reduced consciousness confusion 0.3072229416681082 1.099552849477014 0.2715269952378758 1.0 0.5185231637199055 142 Q8N183,P04062,Q86Y39,Q9HC21,Q96IX5,Q9NZ08,P05067,O96000,P50416,Q9NX14,O43819,Q9Y6M9,P23786,O43681,O43676,P12694,Q9NWS8,Q96CU9,Q9UJS0,P07602,P49770,Q969G3,P11182,P09622,Q9HCC0,P12235,Q13423,O95169,Q9NZJ7,P20674,P35670,Q9NR50,Q9NQ11,P03886,P03915,P00403,Q8NBM4,Q9Y619,Q9NUN5,O96008,Q9NPL8,Q8IUX1,P50336,Q9Y375 44 +Female infertility 0.4942816898370169 1.0979413757086778 0.2722300891597353 1.0 0.5196504767390474 3 O75665 1 +Fatigable weakness of swallowing muscles 0.4941627005435505 1.0969640356739767 0.2726571139489793 1.0 0.5202500956840151 14 Q68CQ7 1 +Small basal ganglia 0.5331562526243894 1.096173529121053 0.2730028415039727 1.0 0.5206941612791002 8 Q96RL7,P00846 2 +Abnormality of metacarpal epiphyses 0.5262336660246598 1.0942728742761272 0.2738353184321882 1.0 0.5220658449878045 5 O95202 1 +Abnormal circulating albumin concentration 0.3735951285333919 1.0931327484339874 0.2743355192539638 1.0 0.5221289113376798 34 Q5XKP0,Q96D53,Q9BT22 3 +Hip dysplasia 0.343787915396677 1.0928937679238984 0.2744404448675863 1.0 0.5221289113376798 49 Q9Y2B2,Q9NVI7,Q15125,O95202,Q96A33,Q7LGA3,Q15907,Q9UHX1 8 +Severe short stature 0.4094434743499965 1.0889839014404314 0.2761609849172846 1.0 0.524276025500999 23 Q96HY6,P21912,Q9Y619,Q96L58,P53701,Q8WVQ1,P16278,Q15392,Q9NX14,P10619 10 +Breast aplasia 0.5112540695324304 1.088446080591548 0.2763982276946346 1.0 0.524276025500999 4 Q9Y619 1 +Hypothermia 0.5189440824865932 1.0883860975397197 0.276424695944826 1.0 0.524276025500999 11 Q5XKP0,P00846,P03886 3 +Fatigable weakness of respiratory muscles 0.4815664286174826 1.0882750868400692 0.2764736853227925 1.0 0.524276025500999 15 Q68CQ7 1 +Increased total bilirubin 0.5107903491001965 1.0858346285393754 0.2775521629156814 1.0 0.5261046346011765 4 P23786 1 +Focal t2 hyperintense basal ganglia lesion 0.390778115111296 1.0834604888291697 0.2786040793436892 1.0 0.5276644462045705 25 Q96CU9,Q9P0J0,P00846,Q7KZN9,P03886,P03915 6 +Cholecystitis 0.5264830126116792 1.0815310856799032 0.2794609406714672 1.0 0.5290698498825476 9 Q9NZJ7,P07602 2 +Ascites 0.381061570542944 1.080095035628261 0.2800998623190824 1.0 0.5296266580083431 26 P04062,O15118,Q8N6S5,O75787,O95235,O60566,Q14739,Q14108,Q15645,Q13510 10 +Aplasia hypoplasia affecting the anterior segment of the eye 0.3808219652049798 1.0779978032341608 0.2810347364835421 1.0 0.5309586165297918 26 O95202,P21912,Q7LGA3,Q96J42 4 +Skeletal muscle hypertrophy 0.3422413935686778 1.0757769802025503 0.2820270098040802 1.0 0.5322968705185773 49 P21912,P53007,Q05086,Q8NAT1,Q9NR77,Q96A33,Q7LGA3,Q9Y4P3,Q96S52,Q14118,Q10713 11 +Dystrophic toenail 0.5333175216091928 1.0757329338243895 0.2820467139173921 1.0 0.5322968705185773 7 O75844,Q969G3 2 +Abnormal visual fixation 0.5367865942567586 1.0749118917396705 0.2824141773734774 1.0 0.5325021233307787 6 P04062,Q13510 2 +Brain imaging abnormality 0.3618193946947631 1.0741274592230832 0.282765559015633 1.0 0.5329176670527759 40 P21912,Q05086,Q9NZJ7,P03886,P07602,Q969X5,Q9BT22,Q969G3,P03915,O43819,P00403 11 +Abnormality of the abdominal organs 0.2864694222416585 1.073463526393541 0.2830631950128426 1.0 0.5332605080209234 373 Q8N183,Q86Y39,P04062,P28288,Q96A33,Q96J42,Q9NX14,P14174,Q9Y6M9,Q5XKP0,O43676,P53007,Q9Y276,P00374,P00813,P00846,P09601,Q9UJS0,Q969G3,P21964,P20674,Q8N511,Q8NCH0,Q96I36,P00403,Q9NUN5,O75431,Q96D53,O96000,Q9BT22,Q9UHX1,P07602,P22830,Q96AA3,P12235,Q9NZJ7,P60033,P03886,Q96DA6,Q9NPL8,Q8IUX1,Q15392,Q8N5K1,Q9H0U3,P21912,P40855,P50416,P23786,O43681,Q9NVI7,O95202,Q96CU9,Q9Y4P3,Q7KZN9,Q14108,Q13510,P35670,Q96RL7,O75845,O75880,Q96S52,O75381,Q9Y2U8,Q96HY6,O75665,Q9HC21,Q9Y5U9,Q9NZ08,O75787,O76024,Q10713,Q9BUB7,Q14739,P03915,Q8NBM4,Q9H9E3,P14927,O15118,O95140,Q9Y375 80 +Abnormality of acid base homeostasis 0.3133599068832068 1.0694941486191278 0.2848470640922422 1.0 0.5357450087090009 187 O14949,Q8N183,Q86Y39,P21912,Q9HC21,Q9BRT2,O96000,P50416,Q9NX14,O43819,Q9Y584,Q9Y6M9,P23786,Q10713,P13073,Q5XKP0,O43676,Q9Y276,Q9NVI7,P22695,Q9BUB7,Q3ZCQ8,Q96CU9,Q9P0J0,Q9UJS0,P00846,Q7KZN9,P11182,Q9HCC0,P12235,P20674,Q70HW3,Q53H12,P03886,Q96I36,P03915,P08574,Q9UBX3,P00403,O75880,Q6P4A7,Q9NUN5,P14927,Q96DA6,Q9NPL8,Q8IUX1,Q9BWD1,Q9Y375 48 +Difficulty walking 0.3241813994415153 1.0649144991837651 0.2869146230976023 1.0 0.5380962894724263 83 P53007,Q9NZJ7,O75298,P35670,O75477,Q9HC21,Q9NR77,P00846,O95140,Q15907,P07602,O14773,Q9NQ11,O43292,Q14118,Q13510,Q15041,O43681 18 +Erythema nodosum 0.4700555068653352 1.062918886339207 0.2878187373855141 1.0 0.5389756584432351 2 P98170 1 +Abnormal atrioventricular valve morphology 0.3688908692006332 1.062331329003985 0.2880852966027969 1.0 0.5389756584432351 35 P04062,O75431,Q96L58,P53701,Q9Y4P3,P06753,P36543,Q9NX14,O75844,P21964,Q12768,P02545 12 +Flat occiput 0.4659929835757862 1.0613082071140714 0.2885498571743268 1.0 0.5391880542819537 16 P40855,Q05086,Q9BUB7,O75381,O60762,P56589,Q9Y2U8 7 +Abnormal midbrain morphology 0.5184850654572402 1.0600026556297573 0.28914339117927 1.0 0.539538673122935 10 O43924,O75665,P04062,Q10713 4 +Thoracic scoliosis 0.5094331059597794 1.0597400114596904 0.2892628946215256 1.0 0.539538673122935 12 O75844,Q9UHX1 2 +Abnormality of extrapyramidal motor function 0.3237009277338299 1.059608093610111 0.2893229299667474 1.0 0.539538673122935 82 O14949,P04062,Q9NP73,Q96IX5,P05067,O75787,P11166,P06753,Q9BPX6,Q6DKK2,Q8NFV4,P11802,Q9Y4P3,P07602,Q9H9P8,Q15043,Q9NWW5,P12235,Q9H078,Q9NZJ7,Q96RL7,O75569,P17900,P16278,Q9NQ11,O96008,O43464,Q9H6K4,Q9UBB4 29 +Areflexia 0.3235887058985282 1.0587584790459006 0.2897097876286894 1.0 0.5397912678573812 92 Q8TB36,Q9BQT8,Q15067,O75787,P56589,Q969X5,Q9BT22,O43819,O15269,P07196,P53007,O95721,Q14118,Q13510,P05023,P12235,O75477,Q9NR77,Q96RL7,O60313,Q9HA77,Q15041,Q8NAT1,Q9H6K4,O95140 25 +Raynaud phenomenon 0.5337652637401966 1.058532936128258 0.2898125432688032 1.0 0.5397912678573812 6 O75844,Q14739 2 +Dysesthesia 0.5337189583912839 1.0582818819306914 0.2899269505093356 1.0 0.5397912678573812 6 Q8NCH0 1 +Abnormality of the wrist 0.374720631801314 1.057317432070934 0.290366740113434 1.0 0.5401735722417053 30 Q15125,Q96L58,Q9H6K4,Q8WVQ1,Q969X5,O75844,Q13510 7 +Abnormal speech prosody 0.5219937191642606 1.0561105306362453 0.2909177198273371 1.0 0.5409439618844959 9 P03915,P00846,P03886 3 +Restless legs 0.5051462835349372 1.054041822323282 0.2918637698886046 1.0 0.5423017143736654 4 O95140,P07196 2 +Amyotrophic lateral sclerosis 0.4527445697044165 1.050799019728852 0.2933509061187827 1.0 0.544275729578021 17 Q68CQ7 1 +Babinski sign 0.3231072247687453 1.0505647804818996 0.2934585238514511 1.0 0.544275729578021 91 P21912,O75787,O14773,Q6DKK2,P07196,O43681,O75298,P00846,P07602,Q15043,Q9NZJ7,O75477,Q9NR77,O60313,O94905,Q9NQ11,O75027,Q9H6K4,O95140,O00400,Q9UBB4 21 +Progressive 0.3152928396855444 1.048000735775931 0.294638267887918 1.0 0.5456965990464333 113 Q8N183,P04062,P28288,P54802,P27544,Q9NR28,Q9NRG9,Q9Y6M9,Q5XKP0,O95470,O75298,Q8N1F7,Q8N766,Q15043,Q13510,Q9BW27,P12235,Q9H078,Q6PJG6,O75477,Q03252,Q96RL7,O60313,O94905,O75569,O60762,Q13126,Q9Y4W6,Q9Y3E5,Q12768,Q96D53,Q9UI09,O00400,Q8NBU5,P02545 35 +Glomerulopathy 0.5162890561821003 1.0473732140827832 0.2949274807290059 1.0 0.5460127887502045 10 Q03252,Q9NZ08,Q14108,P02545,Q8NBM4 5 +Aplasia involving bones of the extremities 0.4853886616013819 1.0463517693414657 0.2953986518915432 1.0 0.5464460007692619 3 Q8NCM8,P02545 2 +Abnormal liver physiology 0.5271392675912131 1.0417585599874908 0.2975236313133744 1.0 0.549935376290425 7 Q13510,O75845 2 +Coronal craniosynostosis 0.5305443019305316 1.0410682139164975 0.2978438905402352 1.0 0.5500860311059734 6 Q6NUK1,Q9NX62 2 +Developmental cataract 0.3227119498731589 1.0401499534610823 0.2982702386145983 1.0 0.5506527482115662 55 P21912,Q9NVI7,Q53H12,O76024,P03886,O00400,Q15800,P00403 8 +Neoplasm of the tongue 0.5060175462256061 1.0394612323335 0.298590279019459 1.0 0.551022829684288 12 O43924,O75665,Q969G3 3 +Pruritus 0.3854625823634887 1.0383014473352823 0.2991297350889694 1.0 0.5517374745219459 25 P35670,Q96A33,P00813,Q14739,P16615,P22830 6 +Stroke 0.364864466140013 1.0381139603701408 0.2992170027843626 1.0 0.5517374745219459 36 O95721,Q96L58,Q9Y4P3,O76024,P03886,P03915,O75844,Q96AA3,P00403 9 +Orthostatic hypotension due to autonomic dysfunction 0.514544678501913 1.0373396965555914 0.299577571599017 1.0 0.552124106260576 10 Q9NZJ7,O43681,P07602 3 +Hypoplastic nipples 0.4952245066929258 1.036735433532518 0.2998591736097533 1.0 0.552124106260576 13 Q9Y2B2,Q96A33 2 +Abnormal circulating porphyrin concentration 0.5017309936558572 1.0347984873345308 0.3007630295121177 1.0 0.5526897280242916 4 P22830 1 +Abnormality of corneal stroma 0.4948897634075876 1.0346917312822077 0.3008128988465546 1.0 0.5526897280242916 13 P04062,O43505,O75845,Q13510,P10619,Q9Y5Z9 6 +Reduced vital capacity 0.4647969617294856 1.0314702270950202 0.3023203630610358 1.0 0.5545749335132711 2 P06753 1 +Elevated tissue non specific alkaline phosphatase 0.4647969617294791 1.0314702270949814 0.302320363061054 1.0 0.5545749335132711 2 Q13043 1 +Aplasia hypoplasia of the femur 0.4834190606454553 1.0294900750325675 0.3032494412561592 1.0 0.5556156760669511 14 Q96HY6,O75431,Q96L58,Q8WVQ1,Q9UHX1 5 +Abnormal liver morphology 0.3086904735282331 1.027562175667816 0.3041558242417785 1.0 0.5561706500421094 248 Q8N183,Q86Y39,P04062,P28288,Q96A33,Q96J42,Q9NX14,P14174,Q9Y6M9,Q5XKP0,O43676,P53007,Q9Y276,P00374,P00813,Q9UJS0,P09601,P00846,P20674,Q8N511,Q9HA77,Q96I36,P10619,Q9Y619,O75431,Q15904,P54802,Q15067,O96000,O95235,P56589,Q9BT22,Q9NWS8,Q01130,P07602,P09622,P22830,Q96AA3,P56556,Q9H078,Q9NZJ7,P60033,O60762,P16278,Q6PGP7,P03886,Q9Y3E5,Q96DA6,Q9NPL8,Q8IUX1,Q9H0U3,P40855,P50416,P23786,Q9NVI7,Q96CU9,Q7KZN9,Q14108,Q13510,P35670,Q96RL7,O75845,O75880,Q96S52,O75381,Q96HY6,O75665,Q9HC21,O75787,Q10713,Q9BUB7,Q14739,P03915,Q9H9E3,P14927,O15118,O95140,Q9Y375 78 +Fatigable weakness of bulbar muscles 0.4605903247304869 1.0252354460443738 0.3052521069343927 1.0 0.557732636302015 16 Q68CQ7 1 +Abnormality of the autonomic nervous system 0.3214466323596301 1.0249467494822495 0.3053883143647047 1.0 0.5577603458551563 55 Q9Y2B2,Q9NZJ7,P21964,Q96RL7,P07602,O76024,P42892,Q8N5K1,O15269,O43681,Q10713 11 +Myelomeningocele 0.5129272039905796 1.020745664324423 0.3073749535564998 1.0 0.5604215228715403 5 O75665,O75845 2 +Abnormality of the plantar skin of foot 0.3507215706123175 1.020323432669042 0.3075750936072321 1.0 0.5604215228715403 43 Q9Y2B2,P21912,O75431,P42167,P16615,Q9Y2U8,P09493 7 +Inappropriate crying 0.522564946734771 1.016597234328512 0.3093450704188316 1.0 0.5627564486735003 7 Q9NZJ7,P07602 2 +Axonal regeneration 0.4981372781291195 1.014548069584868 0.3103213044016022 1.0 0.5636043402685506 4 P07196 1 +Abnormality of femur morphology 0.3148657048738632 1.014335472861243 0.3104227030385376 1.0 0.5636043402685506 64 Q96HY6,Q9H9E3,P16435,Q9NZJ7,O75431,Q96L58,Q96A33,Q7LGA3,Q8WVQ1,P07602,O00116,Q14739,O75844,Q9UHX1 14 +Cerebral visual impairment 0.3173162492879885 1.0123706119171345 0.3113608843375535 1.0 0.5650680603231891 70 Q96N66,Q96A33,Q96CU9,Q96S52,Q8N766,P37268,Q9H490,P03886,Q01105,Q5BJH7,P12235,P00403 12 +Elbow flexion contracture 0.3730950642423334 1.0103016656311503 0.3123507833939494 1.0 0.5660698159562805 26 Q96L58,Q7LGA3,P37268,Q969X5,P50402,P23786 6 +Bilateral cryptorchidism 0.4891699224751589 0.9997644173779028 0.3174245294875948 1.0 0.571743529995631 13 O75665,Q96DA6,P37268,P36543,Q2M1P5,O43924 6 +Atelectasis 0.5034080826406576 0.9976184274008414 0.3184644219871024 1.0 0.5732359595767844 11 Q96L58,P21964,Q13510 3 +Calcinosis 0.5083536147662472 0.9954663458190312 0.3195095044908052 1.0 0.5746681485923615 5 O75844,Q14739 2 +Ovarian cyst 0.4298025093091063 0.994241610191958 0.3201052548464749 1.0 0.5755150270513291 19 O75665,P16435,P21912,Q03252,P10644,Q9Y4P3,Q8NFV4,P02545 8 +Eeg with irregular generalized spike and wave complexes 0.4762870468471381 0.9935343496897324 0.3204496194700312 1.0 0.5759094565202433 3 Q9NQZ5 1 +Abnormality of the liver 0.2872794925124514 0.992780468870014 0.3208169500181306 1.0 0.5763448365237995 315 Q8N183,Q86Y39,P04062,P28288,Q96A33,Q96J42,Q9NX14,P14174,Q9Y6M9,Q5XKP0,O43676,P53007,Q9Y276,P00374,P00813,P00846,P09601,Q9UJS0,Q969G3,P21964,P20674,Q8N511,Q9HA77,Q15645,Q96I36,P10619,Q9Y619,Q9NUN5,O75431,Q15904,P50336,P54802,Q15067,O96000,O95235,P56589,Q9BT22,Q9NWS8,Q01130,P07602,P09622,P22830,Q96AA3,P12235,P56556,Q9H078,Q9NZJ7,P60033,O60762,P16278,Q6PGP7,P03886,Q9Y3E5,Q96DA6,Q9NPL8,Q8IUX1,Q9H0U3,P21912,P40855,P50416,P23786,O43681,Q9NVI7,O95202,Q96CU9,Q9Y4P3,Q7KZN9,Q14108,Q13510,P35670,Q96RL7,O75845,O75880,Q96S52,O75381,Q96HY6,O75665,Q9HC21,Q9Y5U9,O75787,Q10713,Q9BUB7,Q14739,P03915,Q9H9E3,P14927,O15118,O95140,Q9Y375 89 +Psychotic mentation 0.5181000001225748 0.9920361179323984 0.3211799069385044 1.0 0.5765473358677944 7 P00403,P03886 2 +Nevus 0.3627600327447495 0.9912068482643936 0.3215845872735947 1.0 0.5765999136796593 34 P21912,Q9Y4P3,Q8N6S5,Q9UHX1,Q6NUK1 5 +Abnormality of the vasculature of the eye 0.3176230527860849 0.9888170562750276 0.3227526576521751 1.0 0.5782442637874117 77 P21912,O75665,Q9NZ08,Q8WWY3,P00846,Q9Y4P3,P07602,Q13510,P21964,Q9NZJ7,Q96DF8,P17900,Q96S66,Q14739,P03886,Q02978,P03915,Q8NBM4,Q96HR9 19 +Abnormal femoral head morphology 0.4289297962152447 0.9879275705843872 0.3231881216619086 1.0 0.5785745394786616 19 Q7LGA3,Q8WVQ1,O75431 3 +Basal ganglia gliosis 0.50909452573349 0.983033459381072 0.3255909713019251 1.0 0.5814808885224695 9 O43819,P00846 2 +Bilateral tonic clonic seizure with generalized onset 0.5046768825155512 0.9805691228573156 0.3268052671539747 1.0 0.5830795534965477 10 Q9Y320,P04062,Q05086,P11166,Q13510 5 +Neck flexor weakness 0.4919614147910042 0.9797496354143082 0.3272097185282399 1.0 0.5830795534965477 4 Q99720,P35637,P46976 3 +Bladder diverticulum 0.5084910840158012 0.9796146446548408 0.3272763732859303 1.0 0.5830795534965477 9 Q9NWM8 1 +Abnormal central sensory function 0.5192030844317672 0.9795643259944524 0.3273012215242548 1.0 0.5830795534965477 6 O75787 1 +Deviation of the 2nd finger 0.505133162071644 0.9776679377538944 0.3282385842341222 1.0 0.5842114314989707 5 Q9H6K4 1 +Suicidal ideation 0.4554484370435422 0.9755625699804216 0.3292812807150933 1.0 0.5851631860914578 2 Q14203 1 +Abnormality of cardiovascular system electrophysiology 0.30657378604385 0.97198235579123 0.3310593264207428 1.0 0.5876430570673279 119 P21912,P04062,P40855,P09493,Q8TB36,P46976,O75531,Q16836,O95235,P56589,P50416,P06753,P10253,Q9BQP7,Q9NX14,O43819,Q8NFV4,P23786,P47985,Q9BUB7,P00846,Q01130,Q9Y4P3,P07602,Q9H490,P42892,Q9H2M9,P52815,P12235,O95169,O75306,Q9HD47,Q9NZJ7,Q6PJG6,P53701,P03886,Q02978,P13473,P51970,P03915,P00403,O75880,Q9BTV4,O43464,Q96DA6,O75381,P50402,P36543,O75208,O15460,P50336,P02545 52 +Spinal cord lesion 0.509985965688853 0.9668786266721282 0.3336047124392292 1.0 0.5903419796159632 8 O00400,Q12768,Q9Y2U8,O75298 4 +Abnormal heart valve morphology 0.3163549835857988 0.9661591588730636 0.3339645457978697 1.0 0.5907518721829496 79 Q9Y2B2,P04062,P37268,P06753,Q9NX14,Q9UHX1,Q9BUB7,O95202,Q9Y4P3,P21964,Q6ZXV5,P53701,Q8NCH0,P16278,Q6PGP7,O75844,Q6NUK1,Q12768,O75431,Q96L58,P36543,Q2M1P5,P02545 23 +Hemifacial spasm 0.5166096871421458 0.9655026250289532 0.3342931218205971 1.0 0.5911061801033429 6 Q10713 1 +Abnormality of the ankles 0.3369562026789088 0.9652379037017133 0.3344256660571982 1.0 0.5911137204417221 47 Q05086,Q9NZJ7,O75298,O95140,Q9Y4P3,O94905,P07602,O75787,O60762,Q969X5,P06753,Q15043,Q14118,Q9NP72,O75844,Q93063,Q8NFV4,P02545 18 +Insidious onset 0.5163526774157489 0.9641092161522924 0.3349911726088379 1.0 0.5914007482987625 6 Q9NR77,P04062,O60313 3 +Abnormalities of placenta or umbilical cord 0.440146223061487 0.9638893132576056 0.335101422267376 1.0 0.5914007482987625 17 Q9Y2B2,P16435,P16278,Q6PGP7,O75844,Q12768,P02545 7 +Global brain atrophy 0.417855479677299 0.9628452069459564 0.3356252102554369 1.0 0.591963526430709 20 O95169,Q9NP73,Q9NZJ7,P07602,Q9H9P8,P00387,O43819,Q9H2M9,Q9UHX1 9 +Increased connective tissue 0.509231733728888 0.9626696367881528 0.3357133387965501 1.0 0.591963526430709 8 P07196,P02545,O75431 3 +Fetal akinesia sequence 0.5016517301073405 0.9584309987226548 0.3378454702029243 1.0 0.5948765482212744 5 P04062,P06753,Q96S52 3 +Immunodeficiency 0.3099118589185169 0.9575902184927868 0.3382694334574576 1.0 0.5951323300610569 63 P21912,P60033,Q96A33,P00813,P09601,Q9BT22,P21964,Q9H0U3 8 +Slurred speech 0.5079505685406206 0.9555205869800966 0.3393144995095576 1.0 0.5963238801449434 8 O75787,Q96RL7,Q9Y487 3 +Hypointensity of cerebral white matter on mri 0.5144923427021433 0.9540240242859608 0.3400714817415555 1.0 0.5971986996437073 6 P07602 1 +Spastic tetraparesis 0.3921923000201882 0.9505093452314572 0.3418535076958426 1.0 0.5995016359924266 23 Q9NZJ7,P00846,P07602 3 +Hiatus hernia 0.5029071917150864 0.9479836812470364 0.3431377618716293 1.0 0.6009707662103174 9 Q8NCH0 1 +Urticaria 0.4905667038686421 0.9476940081330296 0.3432852521852698 1.0 0.6009707662103174 12 P51648 1 +Congestive heart failure 0.3110167796322401 0.9465152194841208 0.3438858633160224 1.0 0.6012410688645698 67 P21912,P02545,Q9NX14,O43819,Q8NFV4,O95721,Q9BUB7,Q9Y4P3,Q9H2M9,O75306,O95169,P10644,Q70HW3,P16278,Q13043,Q02978,P03886,P03915,P00403,O75880,Q9BTV4,Q96DA6,Q15555,Q9Y375,P09493 25 +Broad columella 0.4856465541307872 0.9441819336838442 0.3450766856988951 1.0 0.6030008978765676 4 Q8TC12 1 +Abnormality of the nasolabial region 0.4989322229677764 0.9434082488335628 0.3454721255442718 1.0 0.6030058918590927 5 Q9Y487,Q8NCH0 2 +Prominent nasolabial fold 0.4989322229677764 0.9434082488335628 0.3454721255442718 1.0 0.6030058918590927 5 Q9Y487,Q8NCH0 2 +Encephalopathy 0.3119541219697166 0.9407204752895424 0.3468481233632297 1.0 0.6049493385532787 106 Q8N183,O75746,P04062,Q86Y39,Q15067,O96000,P50416,Q9NX14,Q9Y6M9,P23786,P53007,O43676,Q9Y276,Q9NVI7,Q9BUB7,Q3ZCQ8,Q96CU9,Q9UJS0,P07602,Q7KZN9,P09622,P56556,Q9H078,Q9NZJ7,Q9HA77,P03886,P03915,P08574,P00403,Q9Y619,Q9NPL8,Q8IUX1,Q8NBU5,Q9Y375 34 +Abnormal waist to hip ratio 0.5086269848682887 0.9399403393437328 0.3472481640268348 1.0 0.6054179114020638 7 P18031,O76024 2 +Aplasia hypoplasia involving bones of the thorax 0.3516217751787518 0.9394422146380832 0.3475037475499185 1.0 0.6056343678933527 38 Q9Y2B2,Q96HY6,P16435,Q8TAA9,O75431,Q96L58,O60566,Q14739,O75844,Q9UHX1,Q15738 11 +Spondyloepimetaphyseal dysplasia 0.51132549391319 0.9368600577618466 0.3488305473601971 1.0 0.6074631981089564 6 Q96L58 1 +Metatarsus valgus 0.4977050288190712 0.9366306384609774 0.3489485862401058 1.0 0.6074631981089564 5 Q8NAT1 1 +Stage 5 chronic kidney disease 0.35926766136974 0.9359269877457596 0.3493107808728157 1.0 0.60786407789348 32 P60033,O95470,Q8IUX1,Q96D53 4 +Ankylosis 0.4974367907180195 0.9351493386077058 0.349711342752208 1.0 0.6081018367555376 5 O75844 1 +Atrial arrhythmia 0.5002475664867186 0.9329224689203406 0.3508600003541864 1.0 0.6089502379028591 9 O95235,Q9BTV4,P50402,P12235 4 +Abnormal urine cytology 0.350909517204914 0.9324530632392188 0.3511024327273544 1.0 0.6091415700330005 38 P21912,P04062,Q8N1F7,P60033,P49257,Q03252,P10644,P09601,Q14108,Q15645,Q02978,Q9BW27 12 +Abnormal arterial physiology 0.3592146736066317 0.9255791686694308 0.3546647232624362 1.0 0.614778149469181 31 Q9NWM8,Q9Y4P3,Q9NZ08,Q14739,O75844,Q8NBM4 6 +Rod cone dystrophy 0.3332354319433209 0.9248539093572816 0.3550419042272335 1.0 0.6150500355936436 47 O75665,P40855,Q96HR9,Q9Y276,Q15067,Q5T8D3,P00846,O75381,P56589,Q8WWY3,Q8TC12,P03886,P03915 13 +Central nervous system cyst 0.3067354437464978 0.9240175936035404 0.3554771557822973 1.0 0.6154997778987908 62 O75665,Q8NAT1,O43505,Q15125,O95202,Q2M1P5,P00846,Q96J42,Q9Y487,O60566,P23786,Q14118,Q969G3,Q15645,Q9UHX1,Q12768,Q9UID3 17 +Abnormal atrioventricular valve physiology 0.3235351234460956 0.9221337325835132 0.3564588235896782 1.0 0.6163992857215114 51 P04062,P09493,Q9NZ08,O95235,Q9NX14,O43819,Q8NFV4,Q9Y4P3,O75306,O95169,P53701,O75844,Q6NUK1,Q8NBM4,O75431,Q96L58,P36543,Q15904,P02545 19 +Reduced subcutaneous adipose tissue 0.4979090609962342 0.9196833747062514 0.3577382430309042 1.0 0.6179422341599303 9 O75844,Q6NUK1,P36543 3 +Aortic valve stenosis 0.4899859944579688 0.919189448394581 0.3579964892139311 1.0 0.6180771158852734 11 P04062,Q15125,P16278,O75844,Q12768 5 +Incomplete penetrance 0.3572997402843041 0.9177198995663516 0.3587655268057124 1.0 0.6191148019703072 32 P21912,P00846,O60313,P52732,O95140,O14979,P11166,Q8WWY3,Q969G3,P03886,P03915,Q9UBB4 12 +Abnormal distal phalanx morphology of finger 0.3255461155487151 0.9169277493247489 0.3591805017804519 1.0 0.6193091326487227 50 Q9Y2B2,Q9H9E3,P16435,O75431,Q96L58,Q7LGA3,Q9Y366,Q8WVQ1,Q96S52,Q9Y2U8,O75844,Q6NUK1 12 +Spastic diplegia 0.3877805396500677 0.9150679323742626 0.3601559684091899 1.0 0.6206427458599654 23 P51648,P07602 2 +Proximal muscle weakness in upper limbs 0.454719691037718 0.9144689553432914 0.3604704832437473 1.0 0.6207014785832818 15 Q9BTV4,O95140,P50402,P50336,P07196 5 +Breech presentation 0.5005769901950041 0.9143924312606164 0.3605106774313587 1.0 0.6207014785832818 8 Q9Y619,P06753,O60313,Q969X5 4 +Abnormal meningeal morphology 0.3613098547232304 0.9129261603552844 0.3612813777727126 1.0 0.6214406230733481 27 O75665,Q96DA6,O75845,P21964,Q9UHX1,Q10713 6 +Sensory ataxia 0.49340720718589 0.9129035336239762 0.3612932789091796 1.0 0.6214406230733481 5 Q9NR77,P54802 2 +Abnormal myelination 0.3050339819530877 0.9078529702391273 0.3639559079156875 1.0 0.6247043772368077 227 Q8N183,Q9Y2B2,Q86Y39,P21912,Q05086,P40855,Q8TB36,Q9Y5U9,Q7LGA3,O96000,O75787,Q9NX14,O43819,Q9Y584,Q9Y6M9,O15269,O43681,P07196,P53007,O43676,Q2TAA5,Q5T8D3,P00374,Q96CU9,P00846,Q9P0J0,Q15907,P07602,Q7KZN9,Q9H490,P49770,P51648,Q14118,P00387,Q5BJH7,Q6ZXV5,Q9NZJ7,P35670,P51572,Q9NR77,Q96RL7,P03886,Q96I36,P03915,P00403,Q96S52,Q9NPL8,O95140,Q8IUX1,O00400,Q9Y375 51 +Desquamation of skin soon after birth 0.4788827024977239 0.9061167922232988 0.3648740381714184 1.0 0.6257311380327116 4 P00813 1 +Hypomimic face 0.4735812244732676 0.9045864493465992 0.3656845167758382 1.0 0.6264216555029972 13 O75787,Q9NQ11,P04062,P12235 4 +Dark urine 0.443470639789667 0.904004962273156 0.365992770130543 1.0 0.6265376463718646 2 P36551 1 +Optic disc coloboma 0.4784966888980367 0.903945759742916 0.3660241632016188 1.0 0.6265376463718646 4 Q10713 1 +Profound global developmental delay 0.4732428723958584 0.9025220383167548 0.3667796198047153 1.0 0.6274626994876131 13 O75381,P37268,P40855,O60313 4 +Tracheal stenosis 0.4915062347815184 0.9024141320314846 0.3668369167577321 1.0 0.6274626994876131 5 Q96HY6,Q15125 2 +Generalized limb muscle atrophy 0.4947165262010877 0.901616216560888 0.3672607735399353 1.0 0.6279545990619748 9 O43819 1 +Generalized onset motor seizure 0.3030318017973178 0.8996931167138411 0.3682835874780898 1.0 0.6286858768562623 59 P21912,P04062,Q05086,Q9Y5U9,P11166,Q01105,P00846,Q8IYI6,P07602,O60566,Q13510,Q96N66,Q9NZJ7,Q6PJG6,O60762,P16278,Q9HA77,Q9Y4W6,P03886,Q9Y3E5,P03915,Q9Y619,Q9Y320 23 +Focal tonic seizure 0.4425942156003478 0.8987752182556978 0.3687724026121839 1.0 0.6289057110425401 2 Q9H936 1 +Paresthesia 0.3602640101991303 0.8977413739056425 0.3693234463403083 1.0 0.6292489987418738 26 Q9NR77,Q9H6K4,O95140,Q9NZ08,P05067,P07196,Q8NBM4 7 +Dysphonia 0.3528331877961846 0.8976290167125767 0.3693833640617987 1.0 0.6292489987418738 34 P21912,P53007,Q96RL7,O95140,Q9Y4P3,Q13510,Q6DKK2 7 +Diffuse cerebral atrophy 0.4163478155409273 0.896900933799562 0.3697717817817634 1.0 0.6296778900407856 19 Q9NZJ7,P07602,O75787,Q9NQ11,Q9HA77,Q10713 6 +Impaired tactile sensation 0.4972179149639528 0.8956699799909598 0.3704290481890397 1.0 0.6305641130606189 8 Q9NR77,O15269 2 +Abnormality of t cell physiology 0.461858171044322 0.8940013477928622 0.3713211700318293 1.0 0.631616076598992 14 P00813,P21964 2 +Demyelinating peripheral neuropathy 0.4230271598114333 0.8935296610968361 0.3715735953013468 1.0 0.6318122240400761 18 Q9NR77,P00846,P07196,P03886 4 +Abnormal talus morphology 0.4295187220483964 0.8905802592840674 0.3731543935210089 1.0 0.6333316557439443 17 P16435,Q969X5,Q9Y4R8,Q99567,O75844,Q9UHX1,P02545,O43175 8 +Abnormality of lower limb joint 0.3020586239119068 0.8884593145775335 0.3742937316307198 1.0 0.6350314857711181 175 Q9Y2B2,P21912,Q96HY6,Q05086,O75665,Q96A33,Q7LGA3,Q9Y366,O75787,P37268,Q969X5,Q9Y584,Q9UHX1,P23786,P53007,P16435,O75298,O95202,Q9Y4P3,Q8WVQ1,P07602,Q15043,Q9NX62,Q14118,P21964,Q13510,Q6ZXV5,Q9NZJ7,O75477,Q9NR77,Q9BYC5,Q86XL3,O94905,O75844,Q15738,Q15041,O75431,Q15125,Q96L58,O95140,Q5JRA6,Q8NBU5 42 +Metatarsus adductus 0.4845385507940484 0.887388067792607 0.3748700054135754 1.0 0.6351373089672879 11 O95202,Q15392 2 +Peripheral neuropathy 0.3013934777297095 0.8873185163824462 0.3749074393209686 1.0 0.6351373089672879 171 Q8N183,P54802,Q8TB36,Q15067,Q9HC21,O76024,Q9Y2R0,O43819,O15269,O43681,P07196,Q10713,P53007,O95470,O95721,Q9NWS8,Q9NVI7,Q96CU9,Q96BR5,P00846,Q9P0J0,P07602,Q7KZN9,P05023,P12235,O95169,Q9NZJ7,P35670,Q9NR77,Q96RL7,O60313,O94905,Q9NQ11,P03886,P03915,Q15041,P00403,Q8IV08,O95140,Q9NPL8,Q8N5K1,P50336 42 +Prominent nasal bridge 0.315375885246036 0.8869936811372519 0.3750823024924004 1.0 0.6352000183333264 53 Q9Y2B2,O75665,P13073,O95721,Q15125,Q5JRA6,P42892,Q2M1P5,O43924,P21964,Q15738,Q9Y2U8,Q10713 13 +Weakness of muscles of respiration 0.3526067509053781 0.8844524960997125 0.3764519952045202 1.0 0.6365837775788731 33 P53007,Q9BTV4,Q15067,O95140,Q969X5,P50402,P50336,Q13510,P12235,P02545 10 +Abnormal joint morphology 0.2938889471276248 0.8841619004534746 0.3766088219721348 1.0 0.6366153527687444 283 Q9Y2B2,P21912,P04062,Q05086,Q96HY6,O75665,P49257,Q96A33,Q7LGA3,Q9Y366,Q9NZ08,O75787,P37268,Q969X5,P14174,Q9Y584,Q9UHX1,O15269,P23786,P07196,P53007,P16435,O75298,Q8TAA9,Q9BUB7,O95202,Q9Y4P3,Q8WVQ1,P07602,Q15043,Q14108,Q9NX62,Q14118,P42892,P21964,Q13510,Q6ZXV5,Q8IZA0,Q9NZJ7,P35670,O75477,Q9NR77,Q96RL7,Q9BYC5,Q86XL3,O94905,Q8NCH0,Q14739,O75844,Q15738,Q15041,P51571,Q8NBM4,O75431,Q15125,Q96L58,Q9H6K4,O95140,P10321,P50402,Q5JRA6,Q15392,Q8NBU5,Q9Y2U8 64 +Abnormality of thyroid physiology 0.3111302922584034 0.8832431553772878 0.3771049094371765 1.0 0.6372201770027538 85 O95470,Q13423,Q9BYC5,P00813,O60313,Q96DA6,Q8N6S5,Q9Y4P3,O60566,O76024,P03886,P21964,P12235,P00403 14 +Polyhydramnios 0.3224691444156095 0.8822160570128083 0.3776599803312328 1.0 0.637924189650411 50 P53007,P04062,Q9NVI7,Q15125,Q9BYC5,Q70HW3,O60566,Q14739,Q6PGP7,Q15645,Q2M1P5,O75844,P21964,Q93063,P02545,Q9UM00 16 +Abnormality of the metacarpal bones 0.3390264997526941 0.880327962807166 0.3786816685749787 1.0 0.6392181894978363 42 O75665,P16435,Q9H9E3,O95202,Q96L58,Q96S52,Q8WVQ1,Q14739,Q9NX62,O43924,Q6NUK1 11 +Neurofibromas 0.4942620339277157 0.8792043545985718 0.3792904837846622 1.0 0.639740318184379 8 P21912 1 +Patellar dislocation 0.3989933138532759 0.8789351086301518 0.3794364612397682 1.0 0.6397523649443293 21 P21964,Q9Y4P3,Q9NX62,Q15125 4 +Enlarged kidney 0.4941581901616971 0.8786260796007388 0.3796040505155398 1.0 0.6398008283743992 8 P60033 1 +Generalized myoclonic seizure 0.33096768697757 0.8770978248405187 0.3804335060518387 1.0 0.6403230700373496 46 P21912,P04062,Q9Y5U9,P11166,Q01105,P00846,P07602,O60566,Q13510,Q96N66,Q9NZJ7,Q6PJG6,O60762,P16278,Q9HA77,Q9Y4W6,P03886,Q9Y3E5,P03915,O43175,Q9Y619 21 +Chronic sinusitis 0.486903087358856 0.8770311097028697 0.3804697408338244 1.0 0.6403230700373496 5 O75665,Q03519 2 +Abnormal mitral valve physiology 0.3400897549774224 0.8733347026075438 0.3824806707240555 1.0 0.6422999018573061 41 P04062,O75844,O75431,Q96L58,P53701,Q9Y4P3,Q9NZ08,Q9NX14,O43819,P09493,Q8NBM4 11 +Ectopia lentis 0.4858195640750651 0.8721683340157821 0.3831165517380221 1.0 0.6428991516419542 10 Q96L58,Q03518,Q12797,Q03519 4 +Toe walking 0.3823577993794778 0.8715196421760606 0.3834704857376656 1.0 0.6431406368976277 23 P50402,Q9NZJ7,P07602 3 +Hand oligodactyly 0.4379199532573768 0.8709032627789618 0.3838069751297763 1.0 0.643237200927275 2 Q15427 1 +Dry skin 0.3528820884845699 0.8675293777990717 0.3856520224391273 1.0 0.6448057037008341 31 O75665,P37268,P00813,P51648 4 +Anemia of inadequate production 0.305200571027988 0.8651046123193019 0.3869813734064211 1.0 0.6456227982102782 68 Q6P4A7,Q9NUN5,Q9BQT8,P00374,Q96DA6,O60313,Q96JJ3,O75027,P22830,Q9UBX3 10 +Cupped ribs 0.4944181676403913 0.8619168060402331 0.3887333001185169 1.0 0.6478419699624325 7 P00813 1 +Pain 0.3020198658759519 0.8581010147459845 0.3908366870840221 1.0 0.650173468389584 189 Q96HY6,P21912,P04062,Q9NZ08,P14174,O15269,P23786,Q8TAA9,P00846,Q9Y4P3,P07602,Q15043,Q14108,Q969G3,P42892,P21964,Q13510,P12235,Q13423,Q9NZJ7,P35670,O75477,P60033,Q9NR77,O60313,Q70HW3,Q9HA77,Q14739,Q15645,Q68CQ7,Q02978,O75844,Q8NBM4,Q9H6K4,Q96D53,O95140,P50402,Q8IUX1,Q2M1P5,Q15165,Q15800,Q9Y2U8 42 +Abnormal thoracic spine morphology 0.3556727663654244 0.8574731025214554 0.3911834737206781 1.0 0.65035342337509 26 O75844,Q9UHX1,P51648,O75477 4 +Vascular neoplasm 0.3467771717078349 0.8519372354981506 0.3942489288106285 1.0 0.6539593462776733 35 O75665,P16435,P21912,O95202,Q7LGA3,Q8N6S5,O60762,Q02978,P10619,Q9UHX1,Q9Y2U8 11 +Multifocal seizures 0.4954537833522343 0.850969309547045 0.3947864014668347 1.0 0.6546152349619196 6 Q9HA77,Q96S52,Q6PJG6 3 +Pulmonary infiltrates 0.4890496897349574 0.850195933190434 0.3952161623853341 1.0 0.6550551508970582 8 Q13510,Q9NZ08,Q8NBM4 3 +Protruding tongue 0.4646244481348973 0.8499803362216716 0.3953360188031074 1.0 0.6550551508970582 13 Q96RL7,Q05086,Q6NUK1 3 +Autoimmune thrombocytopenia 0.477850680784286 0.8483904185108699 0.3962205769533555 1.0 0.6558939120921395 11 P60033,P00813 2 +Tics 0.4945564558972676 0.8461227384152049 0.3974842771187292 1.0 0.6565678159109938 6 Q9UHX1 1 +Infectious encephalitis 0.4770475820345131 0.8437117059178808 0.3988305246285619 1.0 0.657316845429024 11 Q14739,Q9NZ08,Q9BUB7 3 +Hydrocephalus 0.308039756923319 0.8436935190137107 0.3988406900650068 1.0 0.657316845429024 83 O75665,P04062,P40855,Q96J42,Q9NX14,P23786,Q10713,P16435,Q8TAA9,O95202,Q9H490,O60566,Q14118,P21964,P53701,Q6NUK1,Q8NAT1,Q15125,Q96L58,O95140,Q15392 21 +Truncal titubation 0.4500288168730408 0.8414479218589793 0.4000970484377462 1.0 0.6583682296955684 3 Q5T8D3 1 +Bradykinesia 0.3538439795615865 0.8414413927064386 0.4001007048091913 1.0 0.6583682296955684 26 P04062,Q96RL7,Q96IX5,O43464,O75787,Q9NQ11,P06753,Q15043,Q6DKK2,P12235 10 +Limb joint contracture 0.3065339138041117 0.8412860477622807 0.40018770499746 1.0 0.6583682296955684 103 Q9Y2B2,P21912,Q9HC21,Q7LGA3,P37268,Q969X5,P23786,P07196,P16435,Q9BUB7,Q8WVQ1,Q14118,P42892,Q8IZA0,O75477,Q9NR77,O60313,O75844,Q96L58,P50402,Q15392 21 +Abnormality of subcutaneous fat tissue 0.4323438824216727 0.836653524088365 0.4027873503199006 1.0 0.6609843697557344 16 O75431,Q9Y487,P36543,O75844,Q6NUK1,P02545 6 +Heterogeneous 0.324888983179421 0.8341586691798948 0.4041915780178149 1.0 0.6623452316877991 47 Q9Y619,P35232,Q8TB36,Q9NR77,P00846,P12235,P05067,Q9BQE5,P03886,P03915,O75844,P21964,Q9HCC0,P07196,Q15738 15 +Abnormal sacrum morphology 0.348212547282541 0.8336542327353362 0.4044758554156589 1.0 0.6624511478088495 32 Q8TAA9,Q15125,O95202,P53701,Q9Y4P3,Q14739,Q9UM00 7 +Cone cone rod dystrophy 0.4312007011393501 0.8309093019499293 0.4060248683950531 1.0 0.6639327869284617 2 Q6P4Q7 1 +Gingival bleeding 0.4706371418747876 0.829510860360805 0.4068153939451562 1.0 0.6649785347888475 12 P49257,Q96JJ3,Q14108 3 +Coxa valga 0.4069207876728876 0.8287862657885464 0.4072253611869549 1.0 0.6651876867598329 19 Q9H9E3,Q9Y619,Q96L58,Q96A33,Q8WVQ1,P16278,O75844,Q93063 8 +Limb girdle muscular dystrophy 0.4780782372260173 0.8277746323841491 0.4077981436038413 1.0 0.6656513799952182 10 Q9BTV4,P50402,Q14118,P02545 4 +Dyspnea 0.3052672179082917 0.8273811530278621 0.4080210595251266 1.0 0.6657794059106882 104 P04062,Q9Y366,Q969X5,Q9NX14,O43819,P23786,Q9UHX1,P53007,P00846,P07602,P00387,Q13510,P12235,O95169,Q9NZJ7,P53701,P03886,P03915,O75844,P51571,Q96L58,Q68CQ7,Q15165 23 +Death in infancy 0.2991269035786573 0.8268120490757445 0.4083435995896003 1.0 0.6660698431535852 62 P40855,P04062,Q9HC21,Q15067,O95235,P56589,Q9BT22,O43819,Q9NWS8,Q9BUB7,P07602,Q9NZJ7,P20674,P16278,Q12768,Q6NUK1,O43464,O75381,Q15904 19 +Exercise induced muscle cramps 0.489710103435963 0.8199703766009087 0.4122329948683401 1.0 0.6707519916501804 6 P13473 1 +Abnormal nipple morphology 0.2969744499681866 0.8148667101912657 0.4151486103340203 1.0 0.6736806971265338 60 Q9Y2B2,O75665,O95202,Q96A33,Q7LGA3,Q6NUK1,P23786,Q96AA3,Q9UM00 9 +Heterotropia 0.3066352266160548 0.8144534191868512 0.4153852468061019 1.0 0.6737399568048283 54 Q9Y2B2,O75665,P04062,Q05086,Q9NVI7,Q8N766,P00387,O43924,O43819,Q9UHX1 10 +Arthrogryposis multiplex congenita 0.3373649263100652 0.8138548752798551 0.4157280940649934 1.0 0.6740587816507705 39 P04062,Q96S52,Q8NCH0,Q969X5,Q15392,O75844,Q96AA3 7 +Abnormality of the kidney 0.2768049328429906 0.8117847144916832 0.4169151744767152 1.0 0.6755081307977158 367 Q9Y2B2,P21912,Q86Y39,P40855,O75665,Q9Y375,Q8N183,P04062,P49257,Q7LGA3,Q9NZ08,Q96J42,O96000,P50416,O76024,Q9BT22,O43819,Q9Y6M9,Q9UHX1,P23786,Q10713,O95721,O43676,O95470,P16435,Q8TAA9,Q9BUB7,O95202,Q96CU9,P00813,P00846,P09601,Q9Y4P3,O60566,Q14108,P21964,P05023,P35670,P60033,Q9BYC5,Q86XL3,Q8NCH0,O75845,P03886,O43924,Q96I36,P03915,Q8N6S5,P51571,P00403,Q9UM00,Q8NBM4,Q9NUN5,O75431,Q15125,Q96L58,Q96D53,Q9NPL8,O75381,Q8IUX1,Q5JRA6,Q15392,Q8N5K1,Q9Y2U8 64 +Abnormal metacarpal morphology 0.3436392456373394 0.8109506504228233 0.4173940114062033 1.0 0.6759672775875059 34 O75665,P16435,Q9H9E3,Q96L58,Q96S52,Q8WVQ1,Q14739,Q9NX62,O43924 9 +Adducted thumb 0.347564391537687 0.8107801378624196 0.4174919427113805 1.0 0.6759672775875059 30 Q96L58,Q86XL3,Q9Y4P3,Q8NCH0,P42892,Q96AA3 6 +Broad toe 0.3667970586160026 0.8102488793204095 0.4177971498100425 1.0 0.6762238378379615 24 Q9Y2B2,Q9UHX1,Q7LGA3 3 +Shawl scrotum 0.4745498648192563 0.809070530663218 0.4184745779649748 1.0 0.676844807041981 5 Q9Y619,Q9UM00 2 +Aplasia hypoplasia of the spleen 0.4876019574165192 0.8086077280038503 0.4187408181938417 1.0 0.6770377860481482 6 Q96J42 1 +Abnormality of the epiphyses of the distal phalanx of finger 0.4271107215892488 0.8066166447991272 0.4198873810918804 1.0 0.6782526468817281 2 Q9Y2Q9 1 +Reduced tendon reflexes 0.2976729607060563 0.8057277194438346 0.4203998628463807 1.0 0.6785297961457522 176 Q9Y2B2,P04062,P54802,P40855,Q8TB36,Q9BQT8,Q15067,Q9HC21,O75787,P50416,P56589,Q969X5,Q9BT22,O43819,O15269,O43681,P07196,Q10713,P53007,O95721,Q9NWS8,Q8TAA9,Q96BR5,P00846,P07602,Q8N766,Q14118,Q13510,P05023,P12235,Q9NZJ7,O75477,Q9NR77,Q96RL7,O60313,Q9HA77,P03886,P03915,Q15041,Q8NAT1,Q9H6K4,O95140,O75381,P50402,P50336,Q9UBB4 46 +Fetal ultrasound soft marker 0.3888764458013785 0.8020722436829132 0.4225111696882435 1.0 0.6812216479788056 21 Q9Y2B2,O75665,P40855,Q15125,O75381 5 +Meningocele 0.4653280658396023 0.7981237299865089 0.4247986919454305 1.0 0.6835590800974626 12 Q10713,O75665,P21964,O75845 4 +Abnormal anterior eye segment morphology 0.2789092261437191 0.7971686618514986 0.4253530837083377 1.0 0.6838893962763503 324 Q9Y2B2,P21912,P40855,Q05086,O75665,P04062,Q7LGA3,Q9NZ08,Q96J42,P08670,Q96RT7,Q8WWY3,O76024,Q9NX14,Q9UHX1,P23786,Q9Y5Z9,Q10713,Q2TAA5,Q9Y276,Q9NVI7,Q9BUB7,O95202,Q9UJS0,Q9Y4P3,Q8WVQ1,Q8N766,O60566,P51648,Q14118,P21964,Q13510,P12235,Q6ZXV5,P35670,Q96DF8,Q03519,Q9NR77,Q9BYC5,P53701,O60313,Q8NCH0,O75845,Q53H12,Q8TC12,Q13126,Q14739,P03886,Q15645,P03915,O75844,Q8N6S5,Q02978,Q6NUK1,P00403,Q8NBM4,Q9H9E3,Q8NAT1,Q15125,Q96L58,Q9NWM8,Q9H6K4,O75381,O00400,Q96HR9,Q96JJ3,Q15800 67 +Soft skin 0.4757894386734446 0.7947743969474953 0.4267447467660075 1.0 0.6852204394590374 9 Q9NWM8,Q13126 2 +Motor polyneuropathy 0.4644240867556902 0.7927853159708244 0.4279029131689666 1.0 0.6865037288555111 12 P53007,O43819,Q15041,P07196 4 +Urinary urgency 0.46823023529633 0.7924200840601696 0.4281157725253037 1.0 0.6865037288555111 11 Q9NQ11,P04062,O75298,Q9UBB4 4 +Abnormality of the achilles tendon 0.4456437074599355 0.7923842920337932 0.4281366356488143 1.0 0.6865037288555111 14 Q9BTV4,O60313,Q8N2K0,P50402,Q9Y3E5,Q15041 6 +Abnormal peripheral nervous system physiology 0.304778844493087 0.7923254335405424 0.4281709454710805 1.0 0.6865037288555111 54 O95721,Q9Y619,Q9NZJ7,Q8TB36,Q15125,Q9NR77,Q96RL7,Q9UBB4,Q9NQZ5,O60313,O95140,P07602,Q8N2K0,Q9Y3E5,O15269,P07196,O43681 17 +Coloboma 0.3095832338637957 0.7899487694108819 0.4295576879840137 1.0 0.6882318331418903 52 Q9Y2B2,Q8NAT1,O43505,O95202,Q9NX14,P53701,O43924,Q14118,Q2M1P5,Q9NP72,Q9NRG9,Q9H2M9,Q9UHX1,Q12768,Q10713 15 +Congenital contracture 0.3226846561453731 0.788152084341522 0.4306077525433944 1.0 0.6894455937037913 46 P04062,Q96A33,Q96S52,Q8NCH0,Q969X5,Q8NBU5,Q15392,O75844,Q96AA3 9 +Anencephaly 0.4250182414008249 0.7879022639893668 0.4307538767954026 1.0 0.6894455937037913 16 P21964,Q8TAA9,Q96J42,Q2M1P5 4 +Regional abnormality of skin 0.2887099469859809 0.7842434661491278 0.4328972648799407 1.0 0.6921549606407935 140 Q9Y2B2,P21912,P40855,O75665,Q7LGA3,Q969X5,P16615,Q9UHX1,O95721,O95202,Q9Y4P3,Q15907,Q8N766,P42167,Q8NCH0,Q96I36,Q6NUK1,O75431,Q96S52,O75381,Q9Y2U8,P09493 22 +Abnormality of central nervous system electrophysiology 0.2933970831643342 0.7829828889075245 0.4336371602904774 1.0 0.6928571548607905 159 Q9Y2B2,P40855,Q05086,Q9Y5U9,Q96A33,Q9BQE5,P07196,P13073,Q2TAA5,O95202,Q3ZCQ8,Q9NQZ5,P07602,Q14108,Q14118,P21964,Q9NZJ7,Q96N66,O60313,O43292,P03886,Q9UBX3,P00403,Q15125,Q96S52,P50897,O75381 27 +Developmental regression 0.2875638509421014 0.7823624374969077 0.4340016023889981 1.0 0.6931990931745245 129 P21912,P40855,Q15067,Q96IX5,Q9NZ08,P56589,O14773,O76024,O43819,O43681,P13073,O95470,P00846,Q9Y4P3,P07602,P49770,Q15043,Q8NI60,Q13510,O95169,Q9H078,Q9NZJ7,O94905,P17900,Q9NR50,Q9HA77,P03886,P03915,Q8NBM4,O75503,Q96DA6,O75381,Q8N5K1 33 +Clonus 0.3415952116931155 0.7816705603907959 0.4344082073428903 1.0 0.6936081148427021 33 Q9NZJ7,O75298,O75477,Q9BQT8,Q3ZCQ8,O94905,P07602,O75787,Q15043,O75027,O00400 11 +Poor wound healing 0.4824426448744846 0.7808393312731987 0.4348969980817108 1.0 0.6939076756095994 6 O15269 1 +Radioulnar synostosis 0.3785750208171522 0.7803032371543879 0.4352124078415142 1.0 0.6941705695166832 22 O95202,Q96L58,Q9Y4P3,Q8WVQ1 4 +Hyperkinetic movements 0.4660758113275368 0.7799125076562095 0.4354423758023769 1.0 0.6942158860130159 11 Q9NZJ7,P07602 2 +Failure to thrive 0.2795946194741897 0.7759129434676988 0.4378003896676439 1.0 0.6966105647750356 311 Q8N183,P21912,Q86Y39,P40855,O75665,Q9Y375,Q9BQT8,O96000,P37268,O43819,Q9Y6M9,P13073,Q5XKP0,O43676,O95721,Q2TAA5,Q9BUB7,O95202,Q3ZCQ8,Q96CU9,P00813,P00846,Q9P0J0,P46977,P07602,Q9Y4P3,Q7KZN9,P42892,P21964,Q13510,Q96AA3,P12235,Q13423,Q9NZJ7,P20674,P35670,P51572,P60033,Q9BYC5,P53701,O75845,Q14739,P03886,O43924,P03915,O75844,P51571,Q6NUK1,P00403,O75880,Q9H9E3,Q9NUN5,Q15125,Q96L58,Q9NPL8,O75381,Q8N5M9,Q8IUX1,O00116,Q15392,Q96JJ3,Q15800,Q9Y2U8 63 +Lower extremity joint dislocation 0.3024188403548202 0.7741125525266473 0.4388642350302203 1.0 0.6978294334186698 80 Q9Y2B2,O75665,Q15125,O95202,Q96L58,Q96A33,Q9BYC5,Q9Y4P3,Q8WVQ1,Q9NX62,O75844,P21964,Q9UHX1 13 +Decreased adipose tissue 0.4327369714015637 0.7725137872512378 0.4398101842442228 1.0 0.6990842804406274 15 O75844,O75431 2 +Aplasia hypoplasia of the 4th metacarpal 0.4547818535097351 0.7710429214175821 0.4406814910895518 1.0 0.6994959239983655 4 Q96S52 1 +Abnormality of the 4th metacarpal 0.4547818535097351 0.7710429214175821 0.4406814910895518 1.0 0.6994959239983655 4 Q96S52 1 +Intestinal malrotation 0.3431751440876759 0.7709870698934292 0.4407145957277962 1.0 0.6994959239983655 30 O75665,O95202,Q8NCH0,Q15392,P21964,Q9Y2U8 6 +Joint stiffness 0.292170757928108 0.7706118986680002 0.4409370063327524 1.0 0.6994959239983655 58 P16435,Q8TAA9,O75431,O95140,Q9Y4P3,P50402,P51648,O76024,Q8N5K1,O75844,Q9Y2U8 11 +Depression 0.2981948003478378 0.7705394538834726 0.4409799607671987 1.0 0.6994959239983655 112 P04062,O76024,Q6DKK2,O43681,Q9Y4P3,P07602,P21964,Q9NWW5,P12235,Q9NZJ7,P35670,Q96N66,Q96RL7,Q9NQ11,P03886,P03915,P00403,P50897,Q68CQ7,Q8N5K1,Q15165 21 +Accessory spleen 0.4746281327593108 0.7701832314170342 0.441191209398567 1.0 0.6995901902644861 8 Q96J42 1 +Xerostomia 0.4221860826907715 0.7690904188760805 0.4418396355818967 1.0 0.7003773790028828 16 Q15165,Q68CQ7 2 +Hyperextensible skin 0.4417580696451089 0.7681127973440721 0.4424201746087588 1.0 0.7010564527500553 14 Q96L58,Q9NWM8,Q9UHX1,Q8NCH0 4 +Mild microcephaly 0.4798708641729768 0.7670208210700067 0.4430691362773311 1.0 0.7016022611566811 6 P21912 1 +Fulminant hepatic failure 0.4539608301666126 0.7664646123492285 0.4433999002561548 1.0 0.7016437982075417 4 Q16836,P40939,P98170 3 +Abnormal enzyme coenzyme activity 0.2973063945227469 0.7654902782093925 0.4439796532915743 1.0 0.7020790124802933 192 Q9Y2B2,O75665,P04062,P28288,P40855,Q15067,Q9Y5U9,Q96A33,O75787,P50416,P23786,Q10713,Q5XKP0,Q2TAA5,Q9Y276,P22695,P00813,Q9UJS0,P00846,Q01130,P07602,Q14118,P09622,Q13510,Q9HCC0,P12235,Q9H078,Q9NZJ7,P20674,O43505,P35670,P60033,Q96RL7,Q8N511,O75845,O60762,Q14739,P03886,P03915,P10619,P08574,O75880,Q9H9E3,Q9Y619,Q8NAT1,Q9NUN5,O75431,Q96DA6,Q96S52,O15118,Q96JJ3,Q92643,Q15904,P50336 54 +Narrow mouth 0.2982717448004495 0.7627758331026014 0.4455970961314028 1.0 0.7038665777684489 70 Q9NVI7,O75431,Q7LGA3,Q8WVQ1,Q8NCH0,Q9NX62,Q15392,O75844,P21964,Q6NUK1 10 +Lactic acidosis 0.3025612151001816 0.7625680141506441 0.4457210663906974 1.0 0.7038665777684489 96 Q8N183,Q86Y39,Q9HC21,O96000,Q9NX14,O43819,Q9Y6M9,Q10713,Q5XKP0,O43676,Q9Y276,Q9BUB7,Q96CU9,Q9UJS0,P12235,Q70HW3,Q53H12,P03886,P03915,P08574,P00403,Q6P4A7,Q9NPL8,Q8IUX1,Q9Y375 25 +Inappropriate laughter 0.4761813282886314 0.7622214223837382 0.4459278625178919 1.0 0.7038868818270848 7 Q05086 1 +Status epilepticus 0.3160771825191018 0.7608720316299702 0.4467335052492083 1.0 0.7040177811861668 48 P11166,Q9NX14,Q01105,Q9UID3,Q3ZCQ8,P07602,P42892,Q13510,P05023,Q9NZJ7,Q03252,P53701,Q9Y487,Q96F07,Q9HA77,O43292,P52732,Q96S52,Q15392,Q9UBB4 20 +Abnormally large globe 0.46625808594187 0.7602121913173308 0.4471277588437601 1.0 0.704398192393862 10 Q14118,O75431 2 +Chondrocalcinosis 0.4655802233869794 0.7599256022221014 0.4472990570181547 1.0 0.7044272230825896 5 P35670,P02545 2 +Generalized amyotrophy 0.3438846814599402 0.7589535505655802 0.4478803432813292 1.0 0.7048608681148788 27 Q03252,Q96DA6,Q9BQP7,P06753,Q13043,P13473,O43819,Q9Y2U8,P02545 9 +Abnormal aortic valve morphology 0.3269914320949612 0.7569946454221933 0.4490530704262259 1.0 0.7057423426071108 42 Q9BUB7,Q96L58,Q9Y4P3,P37268,O75844,P21964,Q9UHX1,Q6NUK1 8 +Lower limb muscle weakness 0.3156451628490585 0.756118890310175 0.4495779170430904 1.0 0.7060855629633813 48 P53007,O75298,Q9NR77,P00846,O95140,Q969X5,Q969G3,O00400,O43819,Q13510,P07196 11 +Skin pit 0.4300160007941142 0.7550161284473024 0.4502393049997097 1.0 0.706883379025098 15 O95202,P16615 2 +Hypoplasia of teeth 0.3752727007910413 0.7546136104480761 0.4504808548123429 1.0 0.7070217230842221 22 O75844,P51648 2 +Atrophy degeneration affecting the central nervous system 0.2777070211237864 0.7499854950742789 0.4532634407534246 1.0 0.7096968858279921 313 Q9Y2B2,Q86Y39,P40855,Q05086,P04062,Q96A33,Q7LGA3,Q96RT7,O75787,O14773,O76024,Q9BT22,Q01105,O43819,Q6DKK2,Q9UHX1,P07196,Q10713,P13073,Q2TAA5,O75298,Q9BUB7,Q3ZCQ8,P00374,P00846,Q9Y4P3,P07602,Q8N766,Q9H490,P00387,Q13510,Q5BJH7,Q96AA3,Q9NWW5,Q9NZJ7,Q96N66,P51572,Q96RL7,O60313,O75845,Q9NQ11,P03886,O43924,P03915,P00403,Q9UM00,O75880,Q9Y320,Q9H9E3,O00400,O96008,Q96DA6,Q96S52,P50897,O15118,Q68CQ7,Q8N5K1,Q8NBU5,Q15165 59 +Ectopic kidney 0.4024522127547001 0.7486860514026954 0.4540464527936341 1.0 0.7106361799658932 18 Q9Y2U8,Q9UHX1,Q9Y4P3 3 +Type 1 muscle fiber atrophy 0.4707009902303664 0.7484781870491213 0.4541717773436535 1.0 0.7106361799658932 8 Q9BTV4,P50402,P02545 3 +Abnormal 2nd finger morphology 0.4754883673176309 0.7435132664932751 0.4571709926088947 1.0 0.7135853909805762 6 Q9H6K4 1 +Paralysis 0.3078721972917699 0.7430005439318353 0.4574813511184949 1.0 0.7135853909805762 51 P21912,P04062,Q9BTV4,Q8TB36,Q9HC21,Q9NR77,O95140,P17900,P50402,Q68CQ7,Q02978,P50336,Q15165,P02545 14 +Color vision defect 0.428092295256395 0.7426593069176387 0.4576879724472404 1.0 0.7135853909805762 15 O75665,Q9H061,Q9H6K4,O60313 4 +Deep plantar creases 0.4622807017543734 0.7419023114531218 0.4581465252727494 1.0 0.7135853909805762 5 O00170,P21281,P61978,Q9Y487 4 +Limb tremor 0.4724148635668155 0.741727399529399 0.4582525154647023 1.0 0.7135853909805762 7 Q9NR77,Q05086 2 +Neoplasm of the oral cavity 0.4278662995878701 0.7412084360176 0.4585670691876182 1.0 0.7135853909805762 15 O43924,O75665,Q969G3,Q2M1P5 4 +Joint dislocation 0.3011483946323905 0.7386382613326274 0.4601266843643543 1.0 0.7149969637071508 92 Q9Y2B2,O75665,Q15125,O95202,Q96L58,Q96A33,Q9BYC5,Q9Y4P3,Q8NCH0,Q8WVQ1,Q9NX62,P51571,O75844,P21964,Q9UHX1 15 +Dyskinesia 0.2979732618130242 0.737745825810526 0.4606689191831126 1.0 0.7149969637071508 74 P04062,P11166,Q9BPX6,Q01105,O43819,Q9P0J0,P00846,Q6PML9,Q15043,Q5BJH7,O75306,O95169,Q96N66,Q96RL7,O75569,Q9NQ11,Q96F07,P03886,P03915,Q9UBX3,Q9BTV4,Q2M389,O43464,Q96DA6,Q9UBB4 25 +Abnormal delivery 0.3873546959338143 0.7371054744675151 0.4610582102641105 1.0 0.7149969637071508 20 Q9Y619,O60313,Q9Y487,Q969X5,P06753,O75844,P02545 7 +Recurrent bacterial infections 0.3730117105205238 0.7370478675416239 0.461093240460358 1.0 0.7149969637071508 22 P60033,Q8N5M9,P00813,O00165 4 +Bronchitis 0.4683814622670558 0.7356788863878939 0.4619261417696312 1.0 0.715072229435135 8 P60033,Q9H0U3 2 +Peptic ulcer 0.4365425805071641 0.7356024648384003 0.4619726621155375 1.0 0.715072229435135 14 P04062,Q9Y4P3,Q01130,O76024,Q8N5K1 5 +Macroglossia 0.3307542561806738 0.7347082224392274 0.4625172116011109 1.0 0.7154344783678815 38 P21912,Q05086,Q96A33,Q7LGA3,Q9Y4P3,Q96S52 6 +Retinal atrophy 0.3399682088062706 0.7295499254497214 0.4656653400300414 1.0 0.7198208275271489 28 P04062,Q7LGA3,Q8TC12,P51648,Q96HR9,Q10713 6 +Abnormal basal ganglia mri signal intensity 0.336727635691348 0.7276178062350629 0.4668475774820027 1.0 0.7204777066946653 32 Q8N183,Q96CU9,Q9P0J0,P00846,Q9UI09,Q7KZN9,P16278,Q8NI60,Q9BPX6,P03915,P03886 11 +Neonatal respiratory distress 0.3643160525226308 0.7270538061976302 0.4671929951343854 1.0 0.7204777066946653 23 O96000,Q96I36,P23786,Q8WVQ1 4 +Proportionate short stature 0.3357064358229473 0.7268243974549151 0.4673335353574042 1.0 0.7204777066946653 33 Q96HY6,P21912,Q9Y619,Q96L58,P53701,Q8WVQ1,P16278,Q14739,Q5JRA6,Q15392,Q9NX14,P10619 12 +Hepatic encephalopathy 0.459409107293368 0.72624413918892 0.467689117366703 1.0 0.7207538459702001 5 Q9UJS0 1 +Abnormality of toe 0.2933375497136252 0.7260093106731982 0.4678330627814384 1.0 0.7207538459702001 176 Q9Y2B2,O75665,P04062,Q8TB36,Q96A33,Q7LGA3,Q96J42,P37268,P23786,Q9UHX1,P07196,Q10713,P13073,O95202,P00813,Q9Y4P3,Q15907,Q8WVQ1,Q9NX62,P21964,Q13510,Q9NR77,O75845,Q14739,O43924,O75844,Q8N6S5,Q9UM00,O75431,Q15125,Q96L58,O95140,Q5JRA6 33 +Hyperactive deep tendon reflexes 0.45661183047193 0.7251163605324419 0.468380648308508 1.0 0.7213562925820872 11 O75787,O75665,P21912 3 +Abnormality of the gastric mucosa 0.4154629688108076 0.7245351938942041 0.4687372287888014 1.0 0.7216642667085857 16 P04062,Q9Y4P3,Q14739,O76024,Q6PGP7,Q8N5K1 6 +Abnormal corneal epithelium morphology 0.3983155532440928 0.7197095059473368 0.4717038721824116 1.0 0.7242957157669285 18 O75844,P51648,Q14739,Q9NZ08 4 +Abnormal nervous system electrophysiology 0.2949014370217622 0.7172985237314736 0.4731899179476764 1.0 0.7253713468519998 194 Q9Y2B2,P40855,Q05086,Q8TB36,Q9Y5U9,Q96A33,Q9BQE5,O14773,O15269,O43681,P07196,P13073,P53007,O95721,Q2TAA5,O95202,Q3ZCQ8,Q9NQZ5,P07602,Q8N766,Q14108,Q14118,P21964,Q9NWW5,Q9NZJ7,Q96N66,Q9NR77,Q96RL7,O60313,O43292,P03886,P03915,Q9UBX3,P00403,Q15125,Q96S52,P50897,O95140,O75381,Q8NBU5 40 +Steppage gait 0.3913800705284865 0.716955693085705 0.4734014358376956 1.0 0.7253713468519998 19 Q8TB36,Q9NR77,Q96BR5,O95140,O43819,O15269,P05023,P07196 8 +Pace of progression 0.2920333730848518 0.7165767561886291 0.4736352908754924 1.0 0.7253713468519998 171 Q8N183,P04062,P28288,P54802,P27544,Q8TB36,Q9NR28,O75787,O14773,Q9NRG9,Q9Y6M9,P07196,Q10713,Q5XKP0,O95470,O75298,Q8N1F7,Q9NQZ5,Q96BR5,Q9P0J0,Q8N766,Q8N2K0,Q15043,Q14108,Q13510,Q9BW27,P05023,P12235,Q9H078,Q6PJG6,O75477,Q9NR77,Q03252,Q96RL7,O60313,O94905,O75569,O00584,O60762,O14979,Q9NQ11,Q13126,Q9Y4W6,Q9Y3E5,Q12768,Q9BTV4,Q8IV08,P33993,Q96D53,O95140,Q9UI09,P50402,O00400,Q8NBU5,P02545 55 +Abnormality of fontanelles 0.3077772607420542 0.7163626426620892 0.4737674558043281 1.0 0.7253713468519998 50 Q9H9E3,P16435,P40855,Q9Y619,P20674,Q15125,Q9Y487,Q8NCH0,O75381,P56589,P36543,Q9BT22,Q2M1P5,O75844,Q6NUK1 15 +Hyperventilation 0.4617064602473826 0.7157745711887633 0.474130556432778 1.0 0.7253713468519998 9 P11166,P00846,P03915,P03886 4 +T lymphocytopenia 0.4644258462199712 0.7138902569601512 0.4752950424877622 1.0 0.7266104428842417 8 P00813 1 +Hypoketotic hypoglycemia 0.4643894321660262 0.7136899178802195 0.4754189421215253 1.0 0.7266104428842417 8 P50416 1 +Back pain 0.338326428399366 0.7100336648072193 0.4776832601900369 1.0 0.7288624049522153 27 Q9BTV4,P35670,Q8TAA9,P50402,Q969G3,P50336,Q9UGP8 7 +Abnormal umbilicus morphology 0.2893284834114755 0.7093996592293609 0.4780764991710171 1.0 0.7289124647652313 61 Q96DF8,Q9BUB7,Q9NWM8,Q96S52,Q9Y4P3,Q8NCH0,Q96JJ3,Q8NBU5,Q14739,O75844,P21964,Q15738,Q6NUK1 13 +Fibrous tissue neoplasm 0.3834460055912016 0.7083552437131219 0.4787246786925991 1.0 0.7289124647652313 20 P21912,Q96JJ3,Q13126,Q15392 4 +Leukoencephalopathy 0.2981579566005344 0.7082218909894967 0.4788074738831624 1.0 0.7289124647652313 101 Q8N183,Q86Y39,O96000,Q9NX14,Q01105,Q9UHX1,Q9Y6M9,O43681,O43676,Q9BUB7,O95202,Q96CU9,P07602,P49770,Q9NWW5,Q9NZJ7,O60313,P17900,Q9NR50,Q9NQ11,P03886,P51571,Q9NPL8,Q8IUX1,Q9Y375 25 +Abnormal ossification involving the femoral head and neck 0.443442248430188 0.7080015213844577 0.4789443126997226 1.0 0.7289124647652313 4 Q96L58 1 +Muscle fiber inclusion bodies 0.4596196149934173 0.7041198706642281 0.4813581264985105 1.0 0.7310805032647121 9 O43676 1 +Deep palmar crease 0.4527617926497892 0.7029052268468415 0.4821148135952664 1.0 0.7317473850615902 11 O75431 1 +Abnormality of the thymus 0.4217332453489608 0.7019054525829546 0.4827381282861203 1.0 0.7317704158881605 15 P00813 1 +Aplasia hypoplasia of the eyebrow 0.3199764214945411 0.7018919522711303 0.4827465481236843 1.0 0.7317704158881605 43 Q9NVI7,Q15125,O75431,P00813,O75844 5 +Dilatation of the ventricular cavity 0.4092900964066693 0.70140511595107 0.4830502301772847 1.0 0.7317704158881605 2 Q9Y5P6 1 +Tetraplegia tetraparesis 0.308591482422595 0.701352890931676 0.4830828136136684 1.0 0.7317704158881605 49 P21912,Q9NZJ7,P51572,P00846,O94905,P07602,P17900,Q9HA77,Q9UBX3,O43681,Q13423 11 +Hypopigmentation of the skin 0.3103511220937891 0.6979101017735359 0.4852334165203311 1.0 0.7333264057975608 48 P21912,Q05086,Q8IZA0,Q9NZJ7,Q15125,P53701,P07602,P21964,Q9Y2U8 9 +Buphthalmos 0.4540577706354274 0.6971402142135097 0.4857150495331717 1.0 0.7335612284719001 5 Q14118 1 +Abnormal adipose tissue morphology 0.2889787735660524 0.6969134507973384 0.4858569594826907 1.0 0.7335612284719001 62 P21912,Q2TAA5,Q8TAA9,O75431,Q9Y2U8,P42167,P50402,P03915,O75844,Q6NUK1,P09493 11 +Ventricular escape rhythm 0.466686193219012 0.6964750408149191 0.4861313827574087 1.0 0.7336942405630892 6 Q9BTV4,P50402 2 +Bifid nasal tip 0.4084136722173503 0.6962640212725846 0.4862635005815265 1.0 0.7336942405630892 2 P21281 1 +Onion bulb formation 0.461100265167316 0.6956131027338663 0.4866711583008367 1.0 0.7340689680688235 8 Q9NR77,O95140,P07196,Q8TB36 4 +Single transverse palmar crease 0.303633680659302 0.6945464987264138 0.4873395508928824 1.0 0.7343560008222374 51 P40855,O95202,Q96S52,Q15907,O75381,Q96I36,Q9UHX1 7 +Cerebral cortical atrophy 0.2950893656574205 0.6939535886466043 0.4877113151104639 1.0 0.7346759529352788 108 Q9Y2B2,P04062,Q05086,Q7LGA3,Q96RT7,O76024,Q9BUB7,P00846,Q9Y4P3,P00387,Q96AA3,P51572,Q96RL7,Q9NQ11,P03886,O43924,P03915,Q9UM00,P00403,O96008,Q96S52,Q8N5K1 22 +Abnormality of the spleen 0.2862517716733508 0.6931727925089234 0.4882011203163119 1.0 0.7346999903363692 124 Q96HY6,O75665,P04062,P28288,Q96A33,Q9NZ08,Q96J42,Q9BT22,P14174,Q10713,O95202,P00813,P07602,Q14108,P21964,Q13510,Q9NZJ7,P35670,P60033,Q96RL7,O75845,Q14739,Q8NBM4,Q9H9E3,O15118,Q15392,Q9Y2U8,Q9H0U3 28 +Renal cyst 0.2920074972231628 0.6928408139979114 0.4884094557976097 1.0 0.7347668208669232 68 O75665,P40855,Q9H078,Q9NWS8,O43505,Q9Y4P3,Q96J42,Q8N6S5,O75381,P56589,O60566,Q6PGP7,P23786,Q15645,P21964,Q9UHX1,Q10713 17 +Abnormal pulmonary thoracic imaging finding 0.3733265760048458 0.6845216541157791 0.4936458204257663 1.0 0.7411925514897136 21 O75665,Q96L58,Q9NZ08,Q13510,P21964,Q8NBM4 6 +Abnormal blood gas level 0.422501390717581 0.6836034252699135 0.4942256211679452 1.0 0.741821388384981 3 Q9Y3E5 1 +Neck muscle weakness 0.4090519652312809 0.682209562884309 0.4951064486901075 1.0 0.7424981891728853 16 P53007,Q9BTV4,Q9NZJ7,P07602,P06753,P02545 6 +Dysarthria 0.2890652931772631 0.6821249818582075 0.4951599252014489 1.0 0.7424981891728853 165 Q8N183,O14773,O76024,O43819,Q6DKK2,O43681,P07196,Q10713,Q5XKP0,Q96CU9,Q9P0J0,P00846,Q9Y4P3,P07602,Q7KZN9,P49770,P51648,Q14108,P12235,Q9NZJ7,P35670,O75477,Q96RL7,Q9NQ11,O75027,O43292,Q8IV08,Q9H6K4,O15118,Q8N5K1 30 +Primary gonadal insufficiency 0.4554962135750087 0.6811381573337304 0.4957840747895579 1.0 0.7430070997334108 9 P49770,Q9NR50,O76024 3 +Neonatal death 0.4183938541773232 0.6805689480189012 0.4961442807898666 1.0 0.7430070997334108 15 P04062,Q9NVI7,O96000,Q14739,Q6NUK1 5 +Abnormal pyramidal sign 0.2815393726359322 0.6769306240463611 0.4984499727762044 1.0 0.7449528024135991 129 P21912,Q9NP73,Q15067,Q9NZ08,O75787,P11166,O14773,Q9NRG9,Q6DKK2,O43681,P07196,O75298,Q9P0J0,P00846,P07602,Q8N2K0,Q9H9P8,Q15043,P51648,Q8NI60,O75306,Q9H078,Q9NZJ7,Q6PJG6,O75477,P51572,Q9NR77,O60313,O94905,O75569,P17900,Q9NQ11,O75027,Q12768,Q8NBM4,Q9Y619,Q9H6K4,O95140,O00400,Q9UBB4 40 +Macrogyria 0.4576693540322323 0.6768000403548495 0.4985328325447624 1.0 0.7449528024135991 8 Q8NAT1,Q15392 2 +Hyperreflexia 0.2919705533174382 0.6765061335839291 0.4987193531201306 1.0 0.7449528024135991 243 O14949,Q8N183,P04062,O75746,P21912,P40855,Q05086,Q9BQT8,Q15067,O75665,Q96IX5,Q9Y5U9,Q9NZ08,O75787,O14773,Q8WWY3,Q6DKK2,O43681,Q10713,P13073,Q5XKP0,Q2TAA5,Q9Y276,O75298,Q3ZCQ8,Q96CU9,Q9P0J0,P00846,Q9Y4P3,P07602,Q7KZN9,Q15043,Q9HCC0,Q96AA3,Q9NZJ7,P20674,Q96N66,O75477,Q9NR77,O60313,O94905,Q86XL3,P17900,Q9NQ11,Q14739,O75027,O43292,P03886,P03915,Q15041,Q8NBM4,Q9H9E3,Q9Y619,Q9Y320,O75503,Q9H6K4,O95140,O75381,Q8NBU5,O00400,Q96HR9,P50336,Q9UBB4 63 +Abnormal renal echogenicity 0.4049079754601218 0.6757373196873938 0.4992074369982533 1.0 0.7449528024135991 2 Q6PML9 1 +Disproportionate tall stature 0.3343855512898069 0.6754465673000439 0.4993920881559119 1.0 0.7449528024135991 27 O95202,Q9NWM8,Q7LGA3,Q8NCH0 4 +Abnormal cardiac test 0.3981367208540068 0.675336765426813 0.4994618306138481 1.0 0.7449528024135991 17 Q9HD47,P12235 2 +Muscle hypertrophy of the lower extremities 0.4512628545385399 0.6750738949704391 0.4996288180999917 1.0 0.7449528024135991 10 Q9NR77,Q8NAT1,Q14118 3 +Osteopenia 0.2946193494477653 0.6749687271570368 0.4996956338652225 1.0 0.7449528024135991 78 Q9NZJ7,O75431,Q96L58,Q9NWM8,Q9BYC5,Q9Y5U9,Q9Y4P3,P07602,Q9H490,Q13126,O43292,Q14108,Q5JRA6,O75844 14 +Truncus arteriosus 0.4542170414621249 0.6740221569184769 0.500297227235825 1.0 0.745173621929338 9 P21964 1 +Scleroderma 0.4492526930354709 0.6711005894455391 0.5021564514848018 1.0 0.745173621929338 5 Q14739,Q9Y2U8 2 +Female pseudohermaphroditism 0.4040315512708141 0.6706154757631732 0.5024655211335904 1.0 0.745173621929338 2 P04150 1 +Ankyloblepharon 0.4491228070175531 0.670398040355908 0.5026040835408816 1.0 0.745173621929338 5 O75569,P19447,O15111,P18074 4 +Abnormal metabolism 0.2992008433902736 0.6696350588963945 0.5030904591954592 1.0 0.7452564462943299 52 Q2TAA5,Q9NUN5,Q8N511,P46977,O75787,Q9BT22,P51571,Q96AA3,Q9H0U3 9 +Tricuspid valve prolapse 0.4189859799418607 0.6636559177583609 0.5069105593909318 1.0 0.7476858294632758 3 P53701 1 +Supernumerary spleens 0.4488338771829055 0.6613616931571895 0.5083803860688474 1.0 0.7491579210122318 10 O95202,O75665,Q96J42 3 +Milia 0.460027876002842 0.6610775757543443 0.5085625652083567 1.0 0.7491867968286791 6 O75665 1 +Abnormal electrophysiology of sinoatrial node origin 0.4451879495527107 0.6593757970134076 0.5096544801290452 1.0 0.7504631488554804 11 P21912,Q9HD47,P06753,Q02978,P02545 5 +Esodeviation 0.3203636980382578 0.6591326116308528 0.5098106156941031 1.0 0.7504631488554804 40 Q9Y2B2,O75665,P04062,P53007,Q9NVI7,Q8N766,P00387,O43924,Q9UHX1 9 +Aplasia hypoplasia of the thymus 0.4240613951091531 0.6582054187425066 0.5104061433405112 1.0 0.7504631488554804 14 P00813 1 +Cellulitis 0.4468137953330411 0.6579209864187294 0.5105889045443484 1.0 0.7504923994068126 5 P52732 1 +Abnormal autonomic nervous system physiology 0.3281432589965144 0.6566156854725897 0.5114280605885984 1.0 0.7512465741766852 33 P04062,Q9NZJ7,Q96RL7,P07602,O76024,P42892,Q8N5K1,P50336,O43681 9 +Aganglionic megacolon 0.3951289202680168 0.6548997026251038 0.5125323317182433 1.0 0.7523419184909355 17 Q9Y2B2,P21964,Q10713 3 +Aplasia hypoplasia of the cerebral white matter 0.4474188653021422 0.6533853843629682 0.5135078588606419 1.0 0.7526749334893068 10 Q9Y320,P00403,P03886 3 +Emg impaired neuromuscular transmission 0.4585180838815142 0.653076167605853 0.5137071757430274 1.0 0.7526749334893068 6 O60313 1 +Gingival overgrowth 0.3298527078167504 0.6506951612152608 0.5152432873659896 1.0 0.7534881206545478 30 Q9Y5U9,Q96S52,Q9Y4P3,O75845,Q8N766,Q9UM00 6 +Aplasia hypoplasia involving the vertebral column 0.4222793832786488 0.6472111224355424 0.5174953138133982 1.0 0.7558219987486969 14 Q96HY6,Q9H9E3,Q8TAA9,P16278,Q14739,Q15738 6 +Poor motor coordination 0.4031754808872665 0.6435823810332034 0.5198462784102804 1.0 0.756286334985259 16 P35670,Q96RL7,O95140,Q8TC12,Q10713 5 +Anteriorly placed anus 0.4299493983638144 0.6403437045773823 0.5219491731884576 1.0 0.7577636389579119 13 Q9Y2B2,P53701,P16435,Q6NUK1 4 +Chorioretinal coloboma 0.4502798810591962 0.636446368400177 0.5244855267639579 1.0 0.7607807173264626 8 Q10713 1 +Ocular anterior segment dysgenesis 0.2940480244642146 0.6363894078040582 0.5245226430004712 1.0 0.7607807173264626 94 P21912,Q9NVI7,O95202,Q9BYC5,Q7LGA3,Q9Y4P3,Q96J42,Q8WVQ1,Q53H12,Q14118,P03886,O00400,Q15800,P00403 14 +Large for gestational age 0.4443394196693196 0.6360584749310159 0.5247383096113569 1.0 0.7608267252625969 10 Q9Y2B2 1 +Abnormally lax or hyperextensible skin 0.3119114201275605 0.6354169156175339 0.5251565385860673 1.0 0.7609815502530183 44 P04062,Q96L58,Q9NWM8,Q9Y4P3,Q8NCH0,O96000,O75787,Q9UHX1,Q6NUK1 9 +Abnormality of limb epiphysis morphology 0.3280542955712265 0.6345379169131016 0.5257298298446949 1.0 0.7613334556644733 30 Q9H9E3,P16435,O95202,Q96L58,Q7LGA3,Q8WVQ1,Q5JRA6 7 +Acantholysis 0.4422126044483412 0.6331310114010674 0.5266480924694075 1.0 0.7624236286833269 5 P16615 1 +Abnormality of bladder morphology 0.4285034519091847 0.631701382819835 0.5275820242814495 1.0 0.7635357939349621 13 Q9NWM8,Q9Y4P3 2 +Abnormality of the helix 0.3200800730321186 0.6304585462883925 0.5283946163470961 1.0 0.7639919648972133 38 Q9Y2B2,Q7LGA3,O75844,P21964,P23786 5 +Ectropion of lower eyelids 0.3970201577563523 0.6297956184335529 0.5288283127402649 1.0 0.7641930490978847 2 O60716 1 +Lower limb amyotrophy 0.3790673735161259 0.629072973528116 0.5293012831504438 1.0 0.7641930490978847 19 O75298,Q9NVI7,Q9NR77,O00400,P07196 5 +Malabsorption 0.2933525555974635 0.6283032978861315 0.5298052716393618 1.0 0.7645921364591854 53 P40855,Q96A33,P09601,Q9NZ08,Q9Y4P3,O75381,Q14739,O76024,Q8N5K1,Q8NBM4 10 +Abnormal femoral neck head morphology 0.3123655009857441 0.6233513626089313 0.5330536521489826 1.0 0.7664998335614471 43 Q96HY6,O75431,Q96L58,Q96A33,Q7LGA3,Q8WVQ1,Q14739,O75844 8 +Decreased circulating copper concentration 0.411747516072465 0.622785732265436 0.5334253354659619 1.0 0.7664998335614471 3 Q15904,P61966 2 +Juvenile onset 0.3106951105949138 0.6227391686916899 0.5334559388523352 1.0 0.7664998335614471 44 P54802,Q9NR77,Q03252,O15118,P02545,P49770,P06753,O14773,Q9NR50,Q9NQ11,O75027,P16278,P50402,Q9H0U3,Q13510,P07196,Q93063 17 +Chronic fatigue 0.4448646356146888 0.6222123736445213 0.5338022307885266 1.0 0.766758316544118 9 Q9NZJ7,P07602 2 +Abnormality of the hypothenar eminence 0.4111630625365253 0.6194987159650968 0.5355878675435299 1.0 0.7678485348102193 3 Q9NRG9,Q7Z392 2 +Abnormal hand bone ossification 0.4471101880162851 0.6192137702537679 0.5357755415112133 1.0 0.7678485348102193 8 Q8WVQ1,Q15125 2 +Hypochromic anemia 0.4381476704256831 0.6191414362670633 0.5358231881597515 1.0 0.7678485348102193 11 Q96JJ3,Q96DA6,O75027 3 +Functional abnormality of the middle ear 0.2928515615315357 0.6190587118572337 0.5358776816318227 1.0 0.7678485348102193 92 Q9Y2B2,P21912,O75665,O00165,O95202,Q9NWM8,Q96L58,Q7LGA3,Q96JJ3,O75845,O43924,Q96HR9,O75844,P21964,Q6NUK1 15 +Loss of speech 0.3577346424445727 0.6190335003070587 0.5358942899196322 1.0 0.7678485348102193 22 Q9NZJ7,O15118,O94905,P50897,P07602,O43681 6 +Atrophy degeneration affecting the cerebrum 0.2878589539276487 0.6184297717190453 0.5362920778235973 1.0 0.7681796377404838 253 Q9Y2B2,P04062,Q05086,P40855,Q96A33,Q7LGA3,Q96RT7,O75787,O14773,O76024,Q9BT22,Q01105,Q6DKK2,Q9UHX1,Q10713,P13073,Q2TAA5,Q9BUB7,Q3ZCQ8,P00374,P00846,Q9Y4P3,P07602,Q8N766,Q9H490,P00387,Q5BJH7,Q96AA3,Q9NWW5,Q9NZJ7,Q96N66,P51572,Q96RL7,O60313,O75845,Q9NQ11,P03886,O43924,P03915,P00403,Q9UM00,Q9H9E3,Q9Y320,O00400,O96008,Q96S52,P50897,Q8N5K1,Q8NBU5 49 +Tremor 0.2873730680755382 0.6156209013225215 0.5381447531544128 1.0 0.7696371888688809 176 P21912,P04062,Q05086,O75665,O75787,O14773,O76024,Q6DKK2,O43681,P07196,Q10713,Q9BUB7,Q5T8D3,Q9NQZ5,Q96BR5,Q9UJS0,P00846,Q9Y4P3,P07602,Q8N2K0,Q15043,Q8NI60,Q14108,Q13510,P12235,Q9NZJ7,P35670,Q9NR77,Q96RL7,O60313,O94905,Q9NQ11,Q9HA77,O75027,O43292,P03886,Q02978,O43924,P03915,Q6P4A7,O75503,Q9H6K4,Q96DA6,O95140,Q2M1P5,Q9Y2U8,Q9UBB4 47 +Lower limb hypertonia 0.4404993956141438 0.614516841409063 0.5388738475808346 1.0 0.7700297541551533 10 O00400,P21912 2 +Abnormality of the calf musculature 0.3891451241481652 0.6143956545616455 0.5389539065881892 1.0 0.7700297541551533 17 P53007,Q8NAT1,Q9NR77,Q96RL7,Q14118,Q12768,P02545 7 +Weak cry 0.4404315497650345 0.6141369222580565 0.539124851450075 1.0 0.7700297541551533 10 P53007,Q13510,O60313,O75208 4 +Calvarial hyperostosis 0.4510090669786374 0.6134347261037824 0.5395889304993837 1.0 0.7702682130548822 6 P55072,P10644,P22626,Q15043,P31749 5 +Nuclear cataract 0.4381832624202487 0.6115084419921019 0.5408630312631508 1.0 0.7705696460929472 5 P08670 1 +Tented upper lip vermilion 0.3424903333618535 0.6110931942434582 0.54113788514687 1.0 0.7705696460929472 24 Q9Y2B2,Q13045,Q6PJG6,Q9Y5U9,Q4J6C6,Q15907,O60762,Q96F07,Q10471,Q6DKJ4 10 +Abnormal placenta morphology 0.4427518472787097 0.6105663403273638 0.541486711920677 1.0 0.7708281645135865 9 P16278,O75844,Q6PGP7,P02545 4 +Lumbar scoliosis 0.4094097019286938 0.6096500883056578 0.5420936240804437 1.0 0.7709775986921866 3 P21281,P36776 2 +Abnormal patella morphology 0.3261451355469277 0.6074050009882382 0.5435821704359569 1.0 0.771377818034919 28 P21964,Q9Y4P3,Q9NX62,Q15125 4 +Lymphopenia 0.3265425416727459 0.6069297796880715 0.5438975141223936 1.0 0.771377818034919 27 P60033,O95470,P00813 3 +Abnormal sharpey fiber morphology 0.449770193620807 0.6069208993957206 0.5439034077042764 1.0 0.771377818034919 6 P35670,P02545 2 +Motor neuron atrophy 0.348930478139358 0.6049912443682867 0.5451848143459239 1.0 0.7724075711922699 23 Q15165,Q68CQ7 2 +Generalized hypotonia 0.2680464854585805 0.60317928176645 0.5463894288789874 1.0 0.7730311600473976 372 O14949,Q9Y2B2,Q86Y39,P21912,P40855,Q05086,O75665,Q96A33,P50416,Q9BT22,Q01105,O43819,Q9UHX1,Q9Y6M9,P23786,O43681,P13073,Q5XKP0,O43676,O95470,Q10713,Q9NVI7,Q9BUB7,O95202,Q3ZCQ8,P00374,Q96CU9,Q9P0J0,P46977,Q15907,P07602,Q8WVQ1,Q7KZN9,Q8N766,P49770,Q14118,Q5BJH7,Q96AA3,P12235,Q9NZJ7,Q96N66,Q9BYC5,Q8N511,Q8NCH0,Q70HW3,O75845,Q53H12,O43292,O43924,P51571,Q6NUK1,Q9UBX3,O75880,Q6P4A7,Q8NAT1,Q9NUN5,O75431,Q15125,Q96L58,Q96S52,P50897,O75381,Q9BWD1,O00400 64 +Limited elbow movement 0.3202885129735283 0.6008176836717556 0.5479614245830668 1.0 0.7738947275923862 35 Q96L58,Q9H6K4,Q7LGA3,P37268,Q969X5,P50402,P23786 7 +Oromandibular dystonia 0.4481462745892853 0.5983946768588398 0.5495766167825697 1.0 0.7746861578874522 6 Q96RL7 1 +Decreased circulating igg level 0.4141594809817214 0.5973305649538619 0.5502867017238766 1.0 0.7751605033347735 14 P00813 1 +Abnormal atrioventricular conduction 0.4141292960017081 0.5971458551879429 0.5504100050846843 1.0 0.7751605033347735 14 Q9HD47,P50402 2 +Lissencephaly 0.2835439482774801 0.597048199310874 0.5504752009504013 1.0 0.7751605033347735 56 Q9HC21,Q96RT7,Q9BSJ2,Q9NP72,P23786,O95721,Q9NWS8,Q14118,Q9H2M9,Q6ZXV5,O43505,Q86XL3,Q9Y487,Q15738,O43175,Q9Y320,Q8NAT1,P36543,Q15392,Q9H936 20 +U shaped upper lip vermilion 0.4232135444428693 0.5968822353799609 0.5505860085535403 1.0 0.7751605033347735 4 O75665 1 +Diminished movement 0.3743109146212592 0.595369428722194 0.5515965560112841 1.0 0.7758720787851029 19 P13473,Q9NQ11,Q2TAA5,P12235 4 +Fatigue 0.2902033490086182 0.5940076150437937 0.5525070197345592 1.0 0.7764417038538728 84 P21912,Q9NZJ7,Q8NBM4,O60313,Q9NZ08,Q70HW3,P07602,Q53H12,P50416,Q9NQ11,Q14739,Q68CQ7,Q15165,P12235,Q13423 15 +Choreoathetosis 0.3203539646203133 0.5926519844101099 0.5534140814664978 1.0 0.7767850078717756 34 Q9H6K4,Q5XKP0,Q9P0J0,P00846 4 +Vertebral hypoplasia 0.4365569453138473 0.5924815627775304 0.5535281633553835 1.0 0.7767850078717756 10 Q96HY6,Q8TAA9,P16278,Q14739,Q15738 5 +Aplastic clavicle 0.4223089468077144 0.5919640007431094 0.5538746949926565 1.0 0.7767850078717756 4 Q9Y2B2 1 +Abnormally folded helix 0.3798647790280921 0.5914980469176343 0.5541867633885673 1.0 0.7767850078717756 18 Q9Y2B2,P21964 2 +Pleural effusion 0.4299665962195689 0.5913371262452202 0.5542945585520083 1.0 0.7767850078717756 12 P52732,Q9NZ08,Q14739,P14174,Q9UID3,Q8NBM4 6 +Type i diabetes mellitus 0.4217179663141995 0.5912973509351805 0.554321204230459 1.0 0.7767850078717756 13 P03915,P00403,P03886 3 +Hypertriglyceridemia 0.3400480889466198 0.5912899456833319 0.5543261651147824 1.0 0.7767850078717756 24 O95470,P50402,O75431 3 +Redundant neck skin 0.4419502347059246 0.591271174445165 0.5543387403335218 1.0 0.7767850078717756 8 O96000,P36543,Q9Y487 3 +Joint subluxation 0.446529832154128 0.5899217644881676 0.5552431018699098 1.0 0.7767850078717756 6 Q9UHX1 1 +Abnormal placental membrane morphology 0.3900087642418899 0.589283741326487 0.5556709496675869 1.0 0.7767850078717756 2 P21281 1 +Involuntary movements 0.2694263347326093 0.5892360339793941 0.5557029478932372 1.0 0.7767850078717756 350 O14949,P04062,P05067,P13073,Q5XKP0,O75298,Q5T8D3,P00374,P00846,Q9UJS0,Q15043,Q969G3,O95169,O94905,P17900,Q9HA77,O43924,Q02978,P00403,Q9Y619,Q9H6K4,P50897,Q9BWD1,Q9Y2B2,P27544,Q9BQT8,O14773,Q9UHX1,Q15907,P07602,Q96AA3,P12235,Q9NZJ7,O60313,O75027,O43292,P03886,Q9UBX3,Q96DA6,Q9NPL8,P21912,Q05086,O43819,O43681,O95202,Q96CU9,Q9P0J0,Q9Y4P3,Q14108,Q13510,Q9NWW5,Q96N66,P35670,O75477,Q96RL7,O75845,Q6P4A7,O00400,Q9Y2U8,O75665,O75787,Q969X5,O76024,Q01105,Q6DKK2,P07196,Q10713,Q9BUB7,Q3ZCQ8,Q9NQZ5,P00387,Q9NR77,Q9NQ11,P03915,O96008,O95140,Q8NBU5 77 +Thin ribs 0.4213497971885617 0.5891127702646943 0.5557856273770061 1.0 0.7767850078717756 13 O75844 1 +Temporal cortical atrophy 0.4339341033955146 0.5888016370655652 0.5559943475488924 1.0 0.776841101729926 5 O43924 1 +Abnormality of the basal ganglia 0.2906223003513648 0.5868661097539253 0.5572936324222193 1.0 0.7774777651230962 92 Q8N183,Q96N66,Q96RL7,Q96CU9,Q96DA6,O60313,P00846,Q9P0J0,Q7KZN9,Q9NQ11,P00387,P03886,P03915,O43819,P23786,Q96AA3,P00403 17 +Abnormality of the nasal tip 0.2900242344235854 0.5856975221054017 0.5580787995421599 1.0 0.7779604963329992 101 Q9Y2B2,O75665,Q96A33,Q7LGA3,Q9UHX1,P23786,P16435,Q969G3,P42892,P21964,Q96DF8,Q9Y487,O75845,P16278,O43292,O43924,O75844,P10586,Q9H9E3,O75431,P52732,P36543,Q2M1P5,Q93063,P02545 25 +Cutis laxa 0.3204502347913945 0.5855973384990496 0.5581461373430763 1.0 0.7779604963329992 33 Q96L58,Q15904,Q9Y4P3,Q9Y487,Q8NCH0,O96000,O75787,P36543,Q9NX14,Q8NFV4,Q6NUK1 11 +Papilloma 0.4319630970741003 0.5840104167945039 0.5592133037260518 1.0 0.7787412824326524 11 P21912 1 +Cutaneous syndactyly 0.4317365792666207 0.5827278645146776 0.560076512143393 1.0 0.7791791487435111 11 Q9Y619,O60716,P21281,Q2M1P5,P98175,Q9Y2U8 6 +Aplasia hypoplasia of the clavicles 0.4201770650231832 0.5821598083312554 0.5604590427072118 1.0 0.7792985120080965 13 O75844,O75431 2 +Neuroendocrine neoplasm 0.4398938297910899 0.5801760371672604 0.5617959114535611 1.0 0.7804508772921344 8 Q02978,P21912,P02545 3 +Tetraparesis 0.3179795559669959 0.5791268281845103 0.5625035988987874 1.0 0.7809631165187142 35 P21912,Q9NZJ7,P00846,O94905,P07602,P17900,Q9HA77,Q9UBX3 8 +Abnormality of the shoulder girdle musculature 0.3209925707980965 0.5769941618866693 0.5639433993567515 1.0 0.78215195898966 31 P50402,Q9NZJ7,P12235,P07602 4 +Fever 0.2897141093765953 0.5767148287656223 0.5641321134513302 1.0 0.78215195898966 89 Q9NZ08,P14174,P23786,P00813,P00846,P07602,P49770,Q13510,Q9NZJ7,P51572,Q9NR77,Q9NR50,Q9NQ11,Q14739,P03886,P03915,Q8NBM4,P00403,Q96D53 19 +Abnormality of the nasal bone 0.4193722657148531 0.5760326259637991 0.5645931292323807 1.0 0.78215195898966 4 Q6NUK1 1 +Pes valgus 0.439117095567187 0.5759916257040812 0.5646208419676353 1.0 0.78215195898966 8 Q9UHX1 1 +Lethargy 0.2895115531006145 0.5753947191909089 0.5650243747905066 1.0 0.78215195898966 88 Q8N183,Q86Y39,Q9HC21,Q96IX5,O96000,P50416,Q9NX14,Q9Y6M9,P23786,O43676,P12694,Q9NWS8,Q96CU9,Q9UJS0,P49770,P11182,P09622,Q9HCC0,P12235,P20674,Q9NR50,Q9NQ11,P03886,Q9Y619,Q9NUN5,Q9NPL8,Q8IUX1,Q9Y375 28 +Abnormality of temperature regulation 0.2869392714253964 0.5723226615553421 0.5671033998492059 1.0 0.7834514919508538 109 Q05086,Q9HC21,Q9NZ08,P23786,Q5XKP0,Q2TAA5,P00813,P00846,P07602,P49770,Q13510,Q9NZJ7,P51572,Q9NR77,Q9NQ11,Q14739,P03886,P03915,P00403,Q96D53 20 +Inability to walk 0.2890739091569383 0.5675937633861913 0.5703108429131885 1.0 0.7851784774855011 89 O14949,P21912,Q8TB36,O75787,O15269,P07196,Q9NVI7,Q96CU9,P00846,Q15043,Q13510,P12235,Q96N66,Q9NR77,Q96RL7,O94905,O43292,Q15041,Q96S52,O95140 20 +Meningitis 0.4348352481464601 0.5671474248334404 0.5706140244317024 1.0 0.7851886146797239 9 Q8TAA9,Q9NZ08 2 +Parkinsonism with favorable response to dopaminergic medication 0.4289686761761657 0.5670812226688731 0.5706589996880198 1.0 0.7851886146797239 11 Q9NQ11,Q9NZJ7,P07602 3 +Acetabular dysplasia 0.434591403243167 0.5658159156553552 0.5715189259824696 1.0 0.7859024801334586 9 Q96L58,Q9Y584 2 +Distal upper limb amyotrophy 0.4172900486740791 0.5650806201752349 0.5720189295294622 1.0 0.7863553780643681 13 Q9NR77,P07196,Q9BQT8 3 +Ptosis 0.2875882463540312 0.5647283051445843 0.5722585786525962 1.0 0.7864502029320499 228 Q8N183,Q9Y2B2,P04062,Q86Y39,P40855,Q9Y5U9,Q96A33,Q7LGA3,O96000,O76024,Q9NX14,O43819,Q9UHX1,Q9Y6M9,P07196,Q10713,P53007,O43676,O95470,O95202,Q5T8D3,Q96CU9,Q9P0J0,P07602,Q7KZN9,Q969G3,P21964,P12235,Q9NZJ7,O60313,Q86XL3,O75845,P03886,Q9UM00,Q15125,Q9NPL8,O75381,P50402,Q8IUX1,Q9Y375 40 +Limited hip movement 0.4082657205901409 0.5613773352082302 0.574540331466934 1.0 0.7886451734881238 14 Q7LGA3,O94905,Q969X5,O75844,Q93063,P02545 6 +Generalized joint laxity 0.4246407593136047 0.5607072986503376 0.5749970908183015 1.0 0.7890371037792536 12 Q8NCH0 1 +Bilateral tonic clonic seizure 0.2887344371537217 0.5603618094219271 0.5752326755436565 1.0 0.7891253852054687 91 Q9Y2B2,Q05086,P27544,Q9HC21,O75787,Q01105,Q9NQZ5,P00846,P07602,O60566,Q13510,Q9NZJ7,Q96RL7,Q14739,O43292,P03886,P03915,P00403,Q9Y320,Q96S52 20 +Turricephaly 0.4325680846371785 0.5547820760734287 0.5790437284563366 1.0 0.7921766058975905 9 P21964,Q6NUK1 2 +Abnormal hypothalamus morphology 0.4397631789883328 0.5546150803579609 0.579157971889052 1.0 0.7921766058975905 6 O43924,O75665 2 +Short clavicles 0.43240158257745 0.5538752499002518 0.5796642245267956 1.0 0.7921766058975905 9 O75844 1 +Arachnoid hemangiomatosis 0.4395300696273573 0.553403688773797 0.5799870135872034 1.0 0.7921766058975905 6 P21912 1 +Paraganglioma 0.4395300696273573 0.553403688773797 0.5799870135872034 1.0 0.7921766058975905 6 P21912 1 +Hemangioblastoma 0.4395300696273573 0.553403688773797 0.5799870135872034 1.0 0.7921766058975905 6 P21912 1 +Delayed cranial suture closure 0.3183572801663864 0.5532902120980093 0.580064702265737 1.0 0.7921766058975905 31 P40855,O75431,Q8NCH0,O75381,O75844 5 +Impaired temperature sensation 0.4391758834207533 0.5515637555651909 0.5812472743939368 1.0 0.7927014178274434 6 Q9NR77,O15269 2 +Increased blood pressure 0.2855090696175223 0.5512650478114265 0.5814519948473869 1.0 0.7927014178274434 78 P21912,P04062,P28288,O75665,P16435,Q8TAA9,Q9BUB7,Q10713,P03915,Q9Y4P3,Q15645,P03886,Q02978,P42892,O75844,P21964,Q9Y2U8,P00403 18 +Muscle fiber atrophy 0.3552447104683998 0.5495327964785098 0.5826398638936539 1.0 0.7934381648360682 21 P53007,Q9BTV4,Q96RL7,P50402,P23786,P02545 6 +Waddling gait 0.3192215912461358 0.5468103383219902 0.5845090397288559 1.0 0.7946688330718972 28 P53007,Q9BTV4,Q5T8D3,Q8WVQ1,P02545,P50402,Q14118,Q13510,P07196 9 +Urinary retention 0.4380333084287005 0.545633720126221 0.5853177405385173 1.0 0.7953831166032107 6 P20700,Q93063,Q8TAA9 3 +Apnea 0.2872962428045306 0.5439754098722358 0.5864583944726873 1.0 0.796463389840891 88 Q8N183,O75665,P04062,Q86Y39,Q96A33,O76024,O43819,P23786,Q10713,P53007,Q96CU9,Q9P0J0,P00846,P07602,Q7KZN9,O60566,O95169,Q9NZJ7,O60313,P03886,O43924,P03915,O75880,Q8N5K1 24 +Foot dorsiflexor weakness 0.317176876620132 0.5426967971041056 0.5873385798426518 1.0 0.7965082102963404 31 Q9BQT8,Q9NR77,O95140,Q14739,O43819,O15269,P05023,P07196 8 +Widely spaced incisors 0.3971361776738741 0.5412861285406423 0.5883103800597689 1.0 0.7973617976083325 3 Q9BSJ2,Q8WVM7 2 +Pelvic kidney 0.4273273104501233 0.5412559362151046 0.5883311874714259 1.0 0.7973617976083325 10 Q9UHX1 1 +Abnormality of the pubic bone 0.4244881649910322 0.5387172260754391 0.5900819857379409 1.0 0.7986403581382198 5 O95202 1 +Joint contracture of the hand 0.2957964938774685 0.5386314967442869 0.5901411500565621 1.0 0.7986403581382198 48 Q9Y2B2,P16435,Q8IZA0,Q9BUB7,Q8WVQ1,P42892,Q15392,O75844,P07196 9 +Macrocytic anemia 0.3105350612737832 0.5379344729690513 0.5906222879299412 1.0 0.7990568123256515 38 Q9NUN5,P00374,O60313,Q6P4A7 4 +Delayed eruption of primary teeth 0.3806602395559388 0.5358320113942313 0.5920746562455821 1.0 0.7997292310841302 2 Q13045 1 +Abnormal insulin level 0.318324978555096 0.5357340740750559 0.5921423507219274 1.0 0.7997292310841302 27 O75844,O75431 2 +Diffuse white matter abnormalities 0.4262736790028442 0.5354434612506278 0.5923432438090823 1.0 0.7997292310841302 10 O95169,O75306,Q3ZCQ8,P16278,O43819 5 +Spinal rigidity 0.4039763714750123 0.535364371447061 0.5923979219455844 1.0 0.7997292310841302 14 P53007,Q9BTV4,O94905,P50402,P02545 5 +Chronic diarrhea 0.3595954239393214 0.5348829286511596 0.5927308137083083 1.0 0.7997292310841302 20 Q13510,Q96A33,P00813,Q9BT22 4 +Contractures of the joints of the lower limbs 0.2807463896784345 0.5339623824705683 0.5933675604540956 1.0 0.7997292310841302 55 P21912,Q9HC21,Q7LGA3,P37268,Q969X5,P23786,Q8N2K0,Q14118,Q8IZA0,O75477,O60313,O94905,Q86XL3,O60762,Q9Y3E5,Q9BTV4,P50402,P36543,P02545 19 +Asthma 0.3593526139976681 0.5331398780818595 0.5939367560001845 1.0 0.7997292310841302 20 P00813 1 +Reduced protein c activity 0.395653678902087 0.5331040118824447 0.5939615820742559 1.0 0.7997292310841302 3 O60762 1 +Abnormality of the protein c anticoagulant pathway 0.395653678902087 0.5331040118824447 0.5939615820742559 1.0 0.7997292310841302 3 O60762 1 +Reduced protein s activity 0.395653678902087 0.5331040118824447 0.5939615820742559 1.0 0.7997292310841302 3 O60762 1 +Abnormal femoral neck morphology 0.3129171790107394 0.5317552431914614 0.5948955249853964 1.0 0.7997292310841302 35 Q96HY6,Q9H9E3,Q9Y619,O75431,Q96L58,Q96A33,Q9Y487,Q8WVQ1,P16278,O75844,Q93063 11 +Decreased circulating cortisol level 0.4195752252285875 0.5317476605727525 0.5949007773977142 1.0 0.7997292310841302 12 P16435,Q9H0R6,Q969G3,Q9NRG9,Q13423 5 +Abnormal urine carboxylic acid level 0.3178270995537202 0.5314441846423255 0.5951110098497141 1.0 0.7997292310841302 27 Q5XKP0,P12694,Q9H078,Q9Y619,Q9NVI7,Q9BUB7,Q3ZCQ8,Q9H6K4,Q96DA6,O96000,Q53H12,P11182,P50336 13 +Submucous cleft of soft and hard palate 0.3251325012391237 0.5285301669028184 0.5971314148471949 1.0 0.800809534230464 25 Q9Y619,Q8NAT1,O43505,Q96DF8,Q7LGA3,Q14118,Q2M1P5,O75844,Q15392 9 +Abnormal systemic blood pressure 0.2863194195814193 0.5238608439653255 0.6003753307609752 1.0 0.8044575528195911 96 P21912,P04062,P28288,O75665,O43681,Q10713,P16435,Q8TAA9,P49366,Q9BUB7,Q9Y4P3,P07602,P42892,P21964,Q13423,Q9NZJ7,Q15645,P03886,Q02978,P03915,O75844,P00403,P50336,Q9Y2U8 24 +Abnormality of the pharynx 0.2925503732810355 0.5235845248889844 0.6005675472322785 1.0 0.8044811795483544 49 O75665,P54802,Q9H9E3,Q03519,P60033,P21964,P00813,Q03518,Q969G3,Q13510,Q9H0U3 11 +Abnormal exteroceptive sensation 0.2797513913224159 0.522033389439423 0.6016470830847318 1.0 0.8049912191795714 55 Q9NZJ7,Q9NR77,Q9H6K4,O95140,Q9NZ08,Q8NCH0,P07602,Q9NQ11,O15269,P07196,Q8NBM4 11 +Abnormality of the parathyroid gland 0.3576225627293531 0.5207372034396015 0.602549853855034 1.0 0.8054744294497499 20 P35670,P03886,P03915,P21964,P00403 5 +Abnormal anatomic location of the heart 0.4008939283503862 0.5167582163471536 0.6053249512932575 1.0 0.8069406554067279 14 O75665,O75844,Q96J42 3 +Limitation of joint mobility 0.2854402724211362 0.5146928991951907 0.6067676361919654 1.0 0.8076213944461514 100 P16435,Q05086,O75431,Q96L58,Q9HC21,Q9H6K4,Q7LGA3,Q9Y4P3,P37268,Q969X5,P50402,P51648,Q9BT22,O76024,Q8N5K1,O75844,P23786,Q9Y2U8 18 +Osteomyelitis 0.4002993875329094 0.5131783534121217 0.6078265664879823 1.0 0.8087955625351478 14 Q13126 1 +External ear malformation 0.3739495415574903 0.5126892979871533 0.6081686770315984 1.0 0.8087955625351478 17 P40855,Q8NCH0 2 +Reduced factor xi activity 0.3765702600058394 0.5126783296468677 0.6081763507344373 1.0 0.8087955625351478 2 Q9Y672 1 +Hypoglycemic seizures 0.4271844067092453 0.512191215144193 0.6085171907334148 1.0 0.8090153534043785 8 P31751,Q9NNW7,Q16836,P53985,Q13423 5 +Retinal hamartoma 0.4293288670796454 0.5114701653415038 0.6090218742399107 1.0 0.8092342039963587 7 P21912 1 +Movement abnormality of the tongue 0.4192333413948757 0.5111184025574145 0.6092681507084501 1.0 0.8092342039963587 5 Q9NQ11,P10253 2 +Bell shaped thorax 0.4072595090245768 0.5109498776049538 0.6093861542367618 1.0 0.8092342039963587 4 Q8WVQ1 1 +Abnormal aldolase level 0.4190590099809519 0.510206312707058 0.6099069300685096 1.0 0.8092342039963587 5 Q8NAT1 1 +Benign neoplasm of the central nervous system 0.3299724764764533 0.5102003470963687 0.6099111090449987 1.0 0.8092342039963587 24 O75665,P21912,Q02978,Q969G3,O43924 5 +Bowing of the legs 0.2851124628909513 0.5072619084860192 0.6119710618160537 1.0 0.8109799966534629 52 Q96HY6,P16435,O75431,Q96L58,Q7LGA3,Q9Y4P3,Q8WVQ1,Q13126,Q9NX62 9 +Barrel shaped chest 0.4063715932659158 0.5062228113426587 0.6127002429629451 1.0 0.8115254299873467 4 Q14739 1 +Abnormal size of the clitoris 0.361306873060992 0.5041574958956941 0.6141507061472793 1.0 0.8122865826425555 19 P16435,P40855,Q9Y619,P53701,O75381,Q9NX14 6 +Aplasia hypoplasia of the 5th finger 0.3901919099375948 0.5029442495998674 0.6150034692581849 1.0 0.8129305145679883 15 P13073 1 +Ectodermal dysplasia 0.3901227352425471 0.5027393564510433 0.6151475353729641 1.0 0.8129305145679883 3 P21281,Q9Y6K9 2 +Blue sclerae 0.3147365153120161 0.5025817696397399 0.6152583491729382 1.0 0.8129305145679883 26 Q96L58,Q8NCH0,P00387,Q8WVQ1 4 +Abnormality of the palm 0.2744423820501445 0.5022429853386452 0.6154966093291876 1.0 0.8129305145679883 125 Q9Y2B2,P21912,P40855,O75665,P16615,Q9UHX1,O95721,P16435,O95202,Q15907,P42167,Q8NCH0,Q14739,Q96I36,Q6NUK1,O75431,Q96S52,O75381,Q9Y2U8,P09493 20 +Renal hypoplasia aplasia 0.2844851732622349 0.5022102210615425 0.6155196539339651 1.0 0.8129305145679883 89 O75665,P16435,Q9NUN5,Q8TAA9,Q7LGA3,Q9Y4P3,Q15392,O43924,Q96I36,O43819,P21964,Q9UHX1,Q9Y2U8 13 +Abnormal shape of the occiput 0.3130830413488192 0.5011938022764694 0.616234735699918 1.0 0.8134086686064801 30 P40855,Q05086,Q9BUB7,Q96L58,Q9Y366,O60762,O75381,P56589,Q9Y2U8,Q2M1P5,Q12768 11 +Abnormality of hindbrain morphology 0.2736978080916902 0.4998373250876377 0.617189626502324 1.0 0.8142026335306926 293 P21912,O75665,Q9HC21,Q9Y5U9,Q96J42,Q96RT7,O75787,O14773,Q9BT22,Q6DKK2,P23786,Q10713,P13073,Q5XKP0,P16435,Q8TAA9,Q9NVI7,O95202,P00374,Q96CU9,P00846,Q9Y4P3,Q15907,P46977,Q8N766,Q9H490,O60566,Q14108,Q14118,P00387,Q5BJH7,P12235,O75477,P51572,O60313,O75845,O43292,O43924,Q6NUK1,Q9UM00,Q9Y320,Q8NAT1,Q15125,Q8IV08,Q9H6K4,Q96S52,O00400,Q9Y2U8 48 +Tachycardia 0.3141978759752865 0.4980105194545923 0.6184766277379468 1.0 0.8149672006338172 26 P21912,Q9HD47,Q9BTV4,Q01130,P42892,Q9NX14,P50336,P23786,P09493 9 +Chronic kidney disease 0.3071912210729794 0.4957912865841043 0.6200416731196059 1.0 0.8165624549114444 37 P60033,O95470,Q8IUX1,Q96D53 4 +Vertebral segmentation defect 0.3098151930563343 0.4883782398802442 0.6252819520132955 1.0 0.8203243477647431 33 P16435,Q15125,O95202,Q9Y4P3,Q9UHX1,Q9UM00 6 +Abnormal pulmonary valve morphology 0.3960005369450857 0.4873842341188283 0.6259860641074333 1.0 0.8203243477647431 14 Q9Y2B2,P21964,Q9BUB7 3 +Abnormal circulating apolipoprotein concentration 0.3871217361595917 0.4863769769107486 0.6266999110215359 1.0 0.8203243477647431 3 Q9Y487 1 +Prominent veins on trunk 0.3871217361595917 0.4863769769107486 0.6266999110215359 1.0 0.8203243477647431 3 Q9Y487 1 +Abnormal cutaneous elastic fiber morphology 0.3871217361595917 0.4863769769107486 0.6266999110215359 1.0 0.8203243477647431 3 Q9Y487 1 +Visual hallucinations 0.4239341481363247 0.4834119456203997 0.6288032680083262 1.0 0.821303937504669 7 Q9NQ11,Q9NWW5 2 +Abnormal aortic valve physiology 0.2971968976329149 0.4829424378435675 0.6291366081461556 1.0 0.821303937504669 44 P04062,Q15125,Q9Y4P3,Q9NZ08,P02545,P16278,O60566,Q6PGP7,P36543,Q15645,O75844,Q9UHX1,Q12768,Q6ZXV5,Q8NBM4 15 +Nonimmune hydrops fetalis 0.3109063638359315 0.482023601498504 0.6297891803010938 1.0 0.821303937504669 30 P04062,O96000,Q9HA77,Q14739,Q9BT22 5 +Acne 0.3636193461462682 0.4806701723417172 0.6307509335722397 1.0 0.8217545365295696 18 Q92542,P21964,Q9NZ08 3 +Episodic pain 0.4135076371618024 0.4806562834113834 0.6307608063596111 1.0 0.8217545365295696 11 P21912,P23786,Q13423 3 +Abnormality of bone mineral density 0.2732137718955807 0.4799601513159922 0.6312557283101923 1.0 0.8219345566695015 145 Q96HY6,O75665,P04062,Q9Y375,Q9HC21,Q9Y5U9,O95202,Q9Y4P3,Q8WVQ1,P07602,Q9H490,Q14108,Q13510,P12235,Q9NZJ7,P35670,Q9BYC5,O75845,Q14739,Q13126,O43292,O75844,Q8N6S5,O75431,Q15125,Q9NWM8,Q96L58,Q5JRA6,Q15392,Q9Y2U8 30 +Convex nasal ridge 0.3391234867963327 0.4777167968198992 0.6328517875758108 1.0 0.823341583620459 22 O95202,O75844,Q6NUK1 3 +Zonular cataract 0.4124737725290288 0.474943610905284 0.6348271659799409 1.0 0.8244880442039368 11 Q9H6K4,P08670 2 +Slow saccadic eye movements 0.4091491489964839 0.4727509901435377 0.6363908434241425 1.0 0.8260532412671686 12 Q8IV08,Q96RL7,Q9NQ11 3 +Cardiac arrest 0.306311765377931 0.4704034413208773 0.6380668059846424 1.0 0.8272965227848148 35 P04062,Q9HD47,Q9BTV4,Q96DA6,Q9Y4P3,P50416,P50402,Q9NX14,Q8NFV4,P52815,P02545 11 +Scrotal hypoplasia 0.3619494416973932 0.4694247598768217 0.6387660537845747 1.0 0.8274442867800339 18 Q9Y5U9,P46977,Q6NUK1 3 +Abnormal arachnoid mater morphology 0.411426265125053 0.4691649720225228 0.6389517208617967 1.0 0.8274442867800339 11 O75665,Q96DA6,Q9UHX1 3 +Psychosis 0.3072652770302986 0.4652813354224955 0.6417299991113281 1.0 0.8290136910302776 33 Q96RL7,O15118,Q9UJS0,Q9NQ11,O76024,P03886,P03915,Q6DKK2,P00403 9 +Cardiomegaly 0.3025456966584882 0.4612646680727498 0.6446087305477695 1.0 0.8313341814621107 38 P20674,Q96S52,Q9Y4P3,P50416,Q14739,P13473,P23786 7 +Eyelid myoclonus 0.4096930071978687 0.4596246286129447 0.6457856780501205 1.0 0.8323861271202673 11 P00374,Q13510 2 +Bone spicule pigmentation of the retina 0.4146434900134839 0.4583104126140184 0.6467294443448384 1.0 0.8333124713061913 9 Q96S66,Q9UG56 2 +Misalignment of incisors 0.397252265419471 0.4580657813154231 0.6469051820641987 1.0 0.8333124713061913 4 Q96N67,Q9BSJ2,Q8WVM7 3 +Abnormality of the knee 0.2815004580401137 0.4578685544209439 0.6470468798466911 1.0 0.8333124713061913 90 Q96HY6,P21912,Q7LGA3,P37268,Q969X5,P23786,Q9Y4P3,Q8WVQ1,Q9NX62,Q13510,P21964,Q6ZXV5,O75477,Q9NR77,Q86XL3,O94905,Q15041,Q9Y619,O75431,Q15125,Q96L58,Q5JRA6 22 +Impairment of activities of daily living 0.2693076622268091 0.4549151526337573 0.6491702812783351 1.0 0.8355800715448515 61 Q9NZJ7,O75298,Q8TAA9,Q3ZCQ8,P21964,P07602,O15269,P07196,O43681 9 +Congenital nystagmus 0.3737175670257453 0.4535558894184932 0.6501485082401643 1.0 0.8361385224590224 16 P00846 1 +Increased serum iron 0.3809700949316285 0.4531063604658195 0.6504721555422077 1.0 0.8363213428399814 3 Q9Y276 1 +Cerebral hypomyelination 0.3734064769221363 0.4515912274724377 0.6515634909325008 1.0 0.8366267665242075 16 Q9Y2B2,P51572,P49770,Q9NR50,P00387 5 +Myalgia 0.2941248190783242 0.4514307822500303 0.6516791018210784 1.0 0.8366267665242075 44 O60313,Q9NZ08,Q8IUX1,Q14739,P21964,P23786,Q9Y2U8,P12235 8 +Abnormal bone structure 0.2797566670391916 0.4512643090964634 0.6517990650655177 1.0 0.8366267665242075 184 Q9Y2B2,P21912,P04062,P40855,Q96HY6,O75665,Q9Y375,Q9HC21,Q9Y5U9,O95202,Q9Y4P3,Q8WVQ1,P07602,Q9H490,O60566,Q14108,Q13510,P12235,Q9NZJ7,P35670,Q9BYC5,Q9UG56,Q86XL3,O75845,Q14739,Q13126,O43292,O75844,Q8N6S5,Q6NUK1,O75431,Q15125,Q9NWM8,Q96L58,O75381,O00116,Q5JRA6,Q15392,Q96JJ3,Q9Y2U8 40 +Aplasia hypoplasia of the lungs 0.3055712108092182 0.4499901372100678 0.6527175521950128 1.0 0.8368067439259486 33 Q8TAA9,O95202,Q96L58,O96000,O75844,Q6NUK1 6 +Abnormality of blood circulation 0.2759488657942943 0.4498188332827633 0.6528410768726456 1.0 0.8368067439259486 73 P21912,P04062,P49257,Q9NZ08,P05067,O76024,P23786,Q9UHX1,Q9UJS0,Q01130,Q969G3,P21964,Q9Y487,Q14739,Q02978,O75844,Q9UGP8,Q8NBM4,Q9NUN5,P36543,Q8N5K1 21 +Sinus tachycardia 0.4151100570405702 0.4487047578789688 0.6536446519600474 1.0 0.8375958165272243 8 Q02978,P21912,P06753 3 +Coarse hair 0.3413723050002512 0.4479999826737759 0.6541532091112594 1.0 0.837758150220227 21 O75665,P54802,Q9Y276,Q96A33,Q9Y487,Q6NUK1,Q9UM00 7 +Intracranial hemorrhage 0.3080617948583566 0.4479687534691159 0.6541757474398786 1.0 0.837758150220227 27 P21912,P04062,Q9NUN5,P49257,P05067,Q969G3,O75844,P23786 8 +Slowly progressive 0.2688794461164088 0.4471287504396745 0.6547821015645048 1.0 0.8380135932038086 57 Q9BTV4,Q9NR77,Q8IV08,Q9P0J0,Q96BR5,O94905,P33993,O00584,O75787,Q8N2K0,O14773,O14979,O95140,P50402,P02545,P12235,P05023,P07196 18 +Abnormal aortic arch morphology 0.4097726239839441 0.4455282757830666 0.6559380304339202 1.0 0.8389015942935066 10 P21964 1 +Pulmonary hypoplasia 0.307271780157037 0.4435803628352926 0.6573460058048057 1.0 0.8401215500647399 28 Q8TAA9,Q96L58,O96000,O75844,Q6NUK1 5 +Generalized abnormality of skin 0.2815684858938957 0.4434519468608989 0.6574388692563915 1.0 0.8401215500647399 227 Q9Y2B2,P21912,P04062,P28288,P40855,P49257,Q9Y5U9,O75787,P37268,Q9NX14,O15269,P53007,P00374,P00813,Q9UJS0,P00846,Q9Y4P3,P51648,Q14108,P00387,P22830,P21964,Q8IZA0,P35670,P60033,P53701,Q8NCH0,Q14739,Q13126,P03886,Q02978,P03915,O75844,P10619,Q15738,Q8N6S5,Q6NUK1,P00403,Q9H9E3,O75431,Q15125,Q9NWM8,Q96L58,O15118,O75381,P98194,Q15904,Q96JJ3 48 +Progressive extrapyramidal movement disorder 0.4179803738598322 0.4430874652060577 0.6577024713769735 1.0 0.8402240302017313 6 Q9NQ11,Q9H078 2 +Abnormality of prothrombin 0.396302945813195 0.4428368518070116 0.6578837458697584 1.0 0.8402240302017313 13 Q5XKP0,P49257 2 +Atrophy degeneration affecting the brainstem 0.4032196691059341 0.4396158151225364 0.6602153843246894 1.0 0.8418020174234003 12 O60313 1 +Knee flexion contracture 0.3067486986183663 0.4368525168052161 0.6622183097148242 1.0 0.8425134912250122 27 P21912,O75477,Q7LGA3,Q86XL3,O94905,O60762,P37268,Q969X5,P36543,P23786 10 +Dilated fourth ventricle 0.2808990698310272 0.4366881590131338 0.6623375177537376 1.0 0.8425134912250122 51 O75665,Q8NAT1,O43505,Q15125,Q2M1P5,Q96J42,Q9Y487,O60566,Q14118,Q969G3,Q15645,P23786,Q12768,Q9UID3,Q10713 15 +Abnormal pharynx morphology 0.2978048779439755 0.4365442818226546 0.6624418783189765 1.0 0.8425134912250122 40 O75665,P54802,Q9H9E3,Q03519,P60033,P00813,Q03518,Q969G3,Q13510,Q9H0U3 10 +Ovarian gonadoblastoma 0.3622553315804779 0.4329534900236671 0.6650485590196189 1.0 0.8439944257676684 2 P51809 1 +Hypoplasia of the vagina 0.3622553315804779 0.4329534900236671 0.6650485590196189 1.0 0.8439944257676684 2 P51809 1 +Gonadoblastoma 0.3622553315804779 0.4329534900236671 0.6650485590196189 1.0 0.8439944257676684 2 P51809 1 +Female external genitalia in individual with 46 xy karyotype 0.3622553315804779 0.4329534900236671 0.6650485590196189 1.0 0.8439944257676684 2 P51809 1 +Cupped ear 0.3866123384886586 0.4316577084655176 0.6659902091902037 1.0 0.844264551266413 14 Q9Y2B2,Q15392 2 +Abnormality of muscle size 0.2807955166884712 0.431406364555102 0.6661729229653708 1.0 0.844264551266413 207 P21912,Q05086,Q9BQT8,Q9HC21,Q96A33,Q7LGA3,P50416,Q969X5,O43819,O15269,Q6DKK2,P07196,O75298,Q9NVI7,Q9Y4P3,Q14118,Q13510,P12235,O75477,Q96RL7,O60313,Q13126,P13473,Q6P4A7,Q8NAT1,Q9NWM8,Q96DA6,Q96S52,Q9NPL8,P50402,Q68CQ7,O00400,Q15165,Q9Y2U8 34 +Confusion 0.3449851995660443 0.4311480638355421 0.6663607146171753 1.0 0.844264551266413 20 O96008,Q9UJS0,Q9NZ08,P05067,Q9NQ11,Q8NBM4 6 +Cutaneous melanoma 0.3919906460099333 0.4306337018590542 0.6667347320521579 1.0 0.8445062246553996 4 Q99496,P19447,P11802 3 +Abnormality of upper limb joint 0.2755115122614686 0.4280149928454435 0.6686402048585405 1.0 0.8466870195075995 115 Q9Y2B2,Q7LGA3,P37268,Q969X5,P23786,P07196,P16435,Q9BUB7,O95202,Q9Y4P3,Q8WVQ1,P42892,Q13510,Q8IZA0,O75844,Q15125,Q96L58,Q9H6K4,P50402,Q15392 20 +Congenital malformation of the right heart 0.4085334408884281 0.4260355392946855 0.6700819496589816 1.0 0.8478599484188418 9 Q12768,O75665,P40855,O15460 4 +Proptosis 0.2669349950429782 0.4233008728717667 0.6720757575267795 1.0 0.8496365132190398 57 Q9H9E3,P16435,O75431,O95202,Q96L58,Q8WVQ1,Q96JJ3,Q15043,Q9NX62,O75844,Q6NUK1 11 +Retrognathia 0.2785033560217998 0.4219032905390809 0.6730956081404162 1.0 0.8504591615878909 87 O75665,P04062,Q7LGA3,P37268,Q9NX14,Q9UHX1,P53007,Q2TAA5,Q9BUB7,Q8WVQ1,Q8N766,Q96DF8,Q9BYC5,P53701,Q8NCH0,O75844,Q15738,Q6NUK1,Q9Y619,Q15125,Q5JRA6,Q15392 22 +Squamous cell carcinoma of the skin 0.3902367728734209 0.4215521215047677 0.67335195955103 1.0 0.8505498436434064 4 P19447,P18074,P02545 3 +Progressive night blindness 0.3546240581905965 0.420483351321592 0.674132389157764 1.0 0.851069054586021 18 O75665,Q8TC12,Q96HR9,Q10713 4 +Supernumerary nipple 0.3994583288649426 0.4187727310102506 0.6753822356784667 1.0 0.8521799950729393 12 Q9Y2B2,Q7LGA3 2 +Full cheeks 0.3005241499555793 0.4171705060167006 0.6765536967002266 1.0 0.8531908687451133 35 O75431,Q96J42,O75845,Q96JJ3,Q9UHX1 5 +Redundant skin 0.3041808665744909 0.4151982866713821 0.6779967529603708 1.0 0.8540155741445633 27 Q9Y4P3,Q9Y487,Q8NCH0,O96000,P36543,Q9NX14,Q8NFV4,Q6NUK1 8 +Epispadias 0.400594233504302 0.4150591665529282 0.678098590667378 1.0 0.8540155741445633 5 Q9NX14,P53701 2 +Aplasia hypoplasia involving the metacarpal bones 0.3041284172010851 0.4147571897903787 0.6783196617554474 1.0 0.8540155741445633 27 Q9H9E3,P16435,Q96L58,Q96S52,Q8WVQ1,Q14739,Q9NX62 7 +Prominent superficial blood vessels 0.3910334963419954 0.4127794555846216 0.679768204791813 1.0 0.8553718972366668 13 Q9H9E3,Q9Y487,P36543,O75844,Q6NUK1,P02545 6 +Aphasia 0.2973918973198059 0.4123026838221605 0.6801175817551179 1.0 0.8553772110093516 38 O96008,P53701,Q7LGA3,P05067,P03886,Q9NX14,P03915,P21964,P00403 9 +Aplasia hypoplasia of metatarsal bones 0.4080407912030244 0.4121279920508928 0.6802456125753298 1.0 0.8553772110093516 8 Q9H9E3,Q96S52,Q8WVQ1 3 +Ovoid vertebral bodies 0.4080185723792378 0.4120137925299014 0.6803293138778805 1.0 0.8553772110093516 8 Q96L58,P54802 2 +Arrhinencephaly 0.4005261923500475 0.4096398952878299 0.6820701266505074 1.0 0.8566310012552569 11 P21964,Q8TAA9 2 +Widely spaced teeth 0.3008169853491023 0.4073273317541359 0.6837675911969843 1.0 0.8580831257285909 33 Q9Y2B2,Q05086,Q96A33,Q8TC12,P51571 5 +Temporal pattern 0.4023088105423588 0.4056524943688406 0.6849979521723517 1.0 0.858903554723863 10 P12694,P04062,Q9NR77,O60313,P11182 5 +Distal amyotrophy 0.2630983325067755 0.4051595383204539 0.6853602445788667 1.0 0.8591240497876544 58 P21912,P53007,Q8TB36,Q9BQT8,Q9NVI7,Q9NR77,Q96RL7,Q96BR5,O95140,P02545,Q8N2K0,Q13510,Q9Y3E5,O15269,P07196 15 +Abnormal erythrocyte enzyme level 0.335312848944071 0.4044106284870342 0.6859107857486857 1.0 0.8595169460203611 21 P00813 1 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.4084468234485763 0.404225737600623 0.686046729050106 1.0 0.8595169460203611 7 Q9BTV4,P50402 2 +Weak voice 0.4100104967126048 0.4032707600552234 0.6867490497371511 1.0 0.859640863346352 6 O75787 1 +Abnormality of iron homeostasis 0.3981406855780766 0.4026590837918606 0.6871990379691306 1.0 0.859640863346352 5 P28288,Q9Y276 2 +Abnormal cry 0.3962584305594406 0.4011563694368147 0.6883050012481591 1.0 0.859640863346352 12 P53007,Q13510,O60313,O75208 4 +Elevated urinary delta aminolevulinic acid 0.3858520900321524 0.3989928112250558 0.6898985012104792 1.0 0.859640863346352 4 P36551,P08397,P50336 3 +Ileus 0.385852090032152 0.398992811225055 0.6898985012104799 1.0 0.859640863346352 4 P08397,Q01844,P50336 3 +Transient global amnesia 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Brain stem compression 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Visual acuity test abnormality 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Decreased circulating follicle stimulating hormone concentration 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Hypothalamic hypothyroidism 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Ear pain 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Neuralgia 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Progressive pulmonary function impairment 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Decreased pulmonary function 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Intracranial meningioma 0.3973684210526299 0.3987692031943761 0.6900632711627943 1.0 0.859640863346352 5 P31749,Q9UMX1,Q12824,Q969G3 4 +Mortality aging 0.2751711073593673 0.3970911835514446 0.6913002211270753 1.0 0.8609490321496117 111 P04062,P40855,Q15067,Q9HC21,Q96IX5,P05067,O96000,O95235,P56589,Q9BT22,Q9NX14,O43819,O95721,P16435,Q9Y276,Q9NVI7,Q9BUB7,Q9Y4P3,P07602,Q9NZJ7,P20674,Q14739,O75844,Q15738,Q6NUK1,O75431,Q9NPL8,O75381,Q15904 29 +Combined immunodeficiency 0.402816087512602 0.3961639641758133 0.6919840735167258 1.0 0.8615678494366582 9 P00813 1 +Lipodystrophy 0.2964383546415737 0.3946619441388002 0.6930923917479315 1.0 0.8617647271423413 37 O75431,P50402,P42167,O75844,Q6NUK1 5 +Unusual infection by anatomical site 0.355838147795092 0.3944290646481909 0.6932642889576084 1.0 0.8617647271423413 17 Q14739,Q8TAA9,Q9NZ08,Q9BUB7 4 +Achilles tendon contracture 0.3945613042101357 0.3918583665868167 0.6951628664266145 1.0 0.863193341011544 12 Q9BTV4,O60313,Q8N2K0,P50402,Q9Y3E5 5 +Orthostatic hypotension 0.3718555974408077 0.3910899531039713 0.6957307466913627 1.0 0.8634331486005385 15 Q9NZJ7,O43681,P07602 3 +Sparse eyebrow 0.297624676999064 0.3907178020625922 0.6960058386725514 1.0 0.8635419775452656 35 O75844,Q15125,Q9NVI7,O75431 4 +Abnormal pupil morphology 0.3986797338557404 0.3864710729938666 0.6991478220414862 1.0 0.8655758097708673 10 O95202,Q8N6S5 2 +Middle age onset 0.3960975213118326 0.3858004172923888 0.699644486228318 1.0 0.8656028502662799 11 P07602 1 +Abnormality of coagulation 0.2615089639459366 0.3854649216973581 0.6998929907875135 1.0 0.8656028502662799 58 P40855,P28288,Q4KMQ2,P49257,P56589,Q5XKP0,Q9Y276,P47985,Q9UJS0,P09622,Q96AA3,P10644,Q9Y487,O60762,P51571,Q9H9E3,Q9Y619,O75381,P36543 19 +Non midline cleft lip 0.404546406388653 0.3846448853228958 0.7005005342297466 1.0 0.8656028502662799 7 Q96L58 1 +Abnormal elasticity of skin 0.2657960610238508 0.3844128929768455 0.7006724460705782 1.0 0.8656028502662799 64 Q96L58,Q9NWM8,Q9Y4P3,Q8NCH0,O96000,Q13126,O75844,Q9UHX1,Q6NUK1 9 +Limitation of neck motion 0.3679541988791657 0.3840609065465959 0.7009333056544733 1.0 0.8656930239763637 3 O94905 1 +Sepsis 0.3258289983157361 0.3793322932783148 0.7044411218797151 1.0 0.8695592525105083 22 P00813,P42892,Q9BT22 3 +Elevated calcitonin 0.4031754025613645 0.3778003716698025 0.705578897595728 1.0 0.8698122174047893 7 Q02978,P21912 2 +Hypertension associated with pheochromocytoma 0.4031754025613645 0.3778003716698025 0.705578897595728 1.0 0.8698122174047893 7 Q02978,P21912 2 +Pheochromocytoma 0.4031754025613645 0.3778003716698025 0.705578897595728 1.0 0.8698122174047893 7 Q02978,P21912 2 +Nephrolithiasis 0.3065077622673045 0.377021822570758 0.7061573875119898 1.0 0.8699200071539325 25 Q9Y4P3,Q8NCH0 2 +Type ii diabetes mellitus 0.2867982033619707 0.3769057453042114 0.706243651641246 1.0 0.8699200071539325 44 O75665,Q96HR9,Q9Y4P3,Q8WWY3,O76024,P03886,P03915,P00403 8 +Abnormality of the coagulation cascade 0.2903101178268903 0.3747341280257683 0.7078582082055427 1.0 0.8714428595808551 41 Q5XKP0,Q9H9E3,Q9Y619,Q4KMQ2,Q9Y276,P49257,Q9UJS0,P10644,Q9Y487,O60762,P36543,P51571,Q96AA3 13 +Epiphyseal dysplasia 0.4036471650144156 0.3719339914997336 0.7099419961849616 1.0 0.8735414468412024 6 Q8WVQ1 1 +Abnormal urine hormone level 0.3652834599649345 0.3701467651322384 0.7112731391616729 1.0 0.8740124334018636 3 P10644,P04150 2 +Increased urinary cortisol level 0.3652834599649345 0.3701467651322384 0.7112731391616729 1.0 0.8740124334018636 3 P10644,P04150 2 +Short nose 0.275555966366479 0.3697581238952319 0.7115627195343999 1.0 0.8741351670526565 103 O75665,P16435,Q9NVI7,Q96L58,Q9BYC5,Q9Y4P3,Q8NCH0,Q8WVQ1,O75845,Q9H490,O60566,Q9NX62,Q15392,O75844,Q9UHX1,Q6NUK1,Q9UM00 17 +Abnormal form of the vertebral bodies 0.2743071648534193 0.3693100664035413 0.711896623181707 1.0 0.8741586352997859 85 Q96HY6,Q9H9E3,P16435,Q8TAA9,Q15125,O95202,Q96L58,Q10713,P00813,Q9Y4P3,Q8WVQ1,O75845,Q14739,Q9UHX1,Q6NUK1,Q9UM00 16 +Parkinsonism 0.2959286285216566 0.3692233775486076 0.7119612322656459 1.0 0.8741586352997859 34 P04062,Q9NZJ7,O96008,Q96RL7,P07602,O75787,P05067,Q9NQ11 8 +Abnormality of the pulmonary veins 0.4013059319676014 0.368500440930173 0.7125001164239388 1.0 0.8744328200004402 7 Q15392 1 +Abnormal renal pelvis morphology 0.2646683446030359 0.3684146558850024 0.7125640709856018 1.0 0.8744328200004402 56 Q9Y2B2,O75665,P40855,Q15125,P60033,Q8NCH0,O75381,O76024,P23786 9 +Abnormality of the glabella 0.4021616035441006 0.3646806357935768 0.715349814982184 1.0 0.8767072898464695 6 O95202 1 +Delayed menarche 0.4021236168056383 0.3644954839458659 0.7154880454994119 1.0 0.8767072898464695 6 O75844,Q9UJS0 2 +Brisk reflexes 0.3176721155049337 0.3641315881679908 0.7157597496977472 1.0 0.8767072898464695 23 Q9Y5U9,P20674,Q10713 3 +Abnormality of the musculature of the thigh 0.3965707796939165 0.3639321865498622 0.7159086489638513 1.0 0.8767072898464695 9 P07196,Q9BTV4,P50402,P02545 4 +Abnormal aortic valve cusp morphology 0.2980281401988439 0.363808708037676 0.7160008595504546 1.0 0.8767072898464695 27 Q96L58,Q6NUK1,Q9UHX1,Q9Y4P3 4 +Aniridia 0.3963377255331634 0.3627379413755955 0.7168006542180119 1.0 0.8770878346061692 9 P21912,Q15645 2 +Multiple prenatal fractures 0.3996182653570261 0.3601384686898901 0.718743586321895 1.0 0.8780509740278234 7 P06753,Q14739,O75718,Q32P28 4 +Intestinal pseudo obstruction 0.3912533568477722 0.3599780929651651 0.7188635161739312 1.0 0.8780509740278234 11 P00403,P03886 2 +Hypopigmentation of the fundus 0.378011660721585 0.3592050479352304 0.719441700590314 1.0 0.8780509740278234 4 Q9Y619 1 +Abnormality of fundus pigmentation 0.378011660721585 0.3592050479352304 0.719441700590314 1.0 0.8780509740278234 4 Q9Y619 1 +Atrophy degeneration involving the spinal cord 0.3971325674352546 0.3566899019025056 0.7213239660567592 1.0 0.8795609514658762 8 P20700,Q13217,Q8IY17,P54886,P07196 5 +Monochromacy 0.3479404031551291 0.3556815822846026 0.7220790394458028 1.0 0.8799123242498981 2 Q6P4Q7 1 +Self mutilation 0.3949089525948415 0.3554303841237659 0.722267189673931 1.0 0.8799123242498981 9 Q96RL7,Q9UM00 2 +Urogenital sinus anomaly 0.3623611922852112 0.3550303007544042 0.7225668912677115 1.0 0.8799123242498981 3 O14974,P51809 2 +Cerebellar cyst 0.279906910023857 0.3507215916382576 0.7257972254816019 1.0 0.8826797611557723 47 O75665,Q8NAT1,O43505,Q15125,Q2M1P5,Q96J42,Q9Y487,O60566,Q14118,Q969G3,Q15645,P23786,Q12768,Q9UID3 14 +Decreased circulating acth level 0.3976009362200163 0.3501859419424478 0.7261991563522856 1.0 0.8827753034468452 7 O00170,Q12824,P10644,Q9UMX1,Q969G3,P31749 6 +Abnormality of the skull base 0.2630846767796486 0.3501062832216716 0.726258935626517 1.0 0.8827753034468452 64 O75665,Q96J42,P23786,Q9UHX1,Q9UID3,Q10713,Q9H490,O60566,Q14118,Q969G3,Q96AA3,O43505,Q9Y487,Q14739,Q15645,Q12768,Q8NAT1,Q15125,Q96L58,Q9NPL8,Q2M1P5 21 +Abnormality of the urinary system physiology 0.2677468590338632 0.3455691847562376 0.7296665077553313 1.0 0.8853542906137308 290 Q8N183,P21912,P04062,Q86Y39,P40855,O75665,Q9Y375,Q9BQT8,Q9HC21,Q9BRT2,P49257,Q9Y5U9,Q9NZ08,O96000,P50416,O76024,Q9BT22,Q9NX14,O43819,Q9Y6M9,P23786,Q10713,Q5XKP0,O43676,P53007,Q9Y276,O95470,Q9NVI7,O95721,Q8TAA9,Q9BUB7,Q96CU9,P00813,Q9UJS0,P09601,P00846,Q9Y4P3,Q3ZCQ8,Q14108,P11182,Q9HCC0,P05023,P12235,Q13423,P35670,P60033,Q8NCH0,Q53H12,P03886,Q96I36,P03915,P00403,O75880,Q8NBM4,Q9NUN5,O75431,Q9H6K4,Q96D53,Q96DA6,Q9NPL8,Q8IUX1,Q5JRA6,Q8N5K1,Q9Y2U8 64 +Abnormality of the clitoris 0.3211037219957777 0.3450464983297868 0.7300594142285246 1.0 0.8853542906137308 22 P40855,P16435,P51809,Q9Y619,P53701,O75381,Q9NP72,P56589,Q9NX14,Q9H2M9 10 +Thin skin 0.2956917689693279 0.3444958159622453 0.730473442076959 1.0 0.8853542906137308 27 O75844,Q13126 2 +Cerebral calcification 0.2915725365111132 0.3424064231899641 0.7320450553202997 1.0 0.8868973011968929 36 O60313,O75845,Q14118,P03886,P03915,P23786,P00403 7 +Decreased circulating gonadotropin concentration 0.3974846446329213 0.3420082705199642 0.732344668197521 1.0 0.8868973011968929 6 Q12824,Q9UMX1,Q969G3,Q8IY17,P31749 5 +Secondary growth hormone deficiency 0.3974846446329215 0.3420082705199639 0.7323446681975212 1.0 0.8868973011968929 6 O00170,Q12824,Q9UMX1,Q969G3,P31749 5 +Urinary bladder sphincter dysfunction 0.3876517356350912 0.3409625131657808 0.7331318026797726 1.0 0.8871510889570359 11 O75298 1 +Abnormality of peripheral nerves 0.2757430599230206 0.3406068669357883 0.733399559194658 1.0 0.8872421025909646 49 O95721,Q9Y619,Q9NZJ7,Q8TB36,Q9NR77,Q96RL7,Q9UBB4,O95140,P07602,Q8N2K0,Q9Y3E5,O15269,Q93063,P07196,O43681 15 +Genu valgum 0.2930402082474188 0.338456742320694 0.7350190201572393 1.0 0.888814777386161 33 Q9Y619,O75431,Q9NR77,Q96L58,Q7LGA3,Q9Y4P3,P16278,Q9NX62,Q2M1P5,Q93063 10 +Abnormal uvea morphology 0.272302907084129 0.336936928452014 0.736164446429969 1.0 0.8896527063071852 108 P21912,P40855,Q05086,Q7LGA3,Q96J42,Q96RT7,Q9NX14,P14174,Q9UHX1,Q10713,Q5XKP0,O95202,Q9Y4P3,Q14118,Q9NR77,P53701,Q15645,Q02978,Q8N6S5,Q8NAT1,O75381 21 +Abnormal odontoid tissue morphology 0.2798505648108699 0.3346377638599806 0.7378983542508206 1.0 0.8908103112083046 46 O75665,Q96L58,P53701,Q9Y4P3,Q9Y366,P51648,Q5JRA6,Q96JJ3,P21964 9 +Calvarial skull defect 0.3943904158771737 0.3344460186457696 0.7380430187103992 1.0 0.8908103112083046 7 O95202 1 +Non hodgkin lymphoma 0.3838984205767474 0.3342170452325415 0.7382157825816611 1.0 0.8908103112083046 12 P00813 1 +Vomiting 0.2734421579349685 0.3341554833209727 0.7382622342219767 1.0 0.8908103112083046 100 Q8N183,Q86Y39,O96000,Q9NX14,Q9Y584,P23786,Q9Y6M9,O43676,Q2TAA5,P22695,Q96CU9,Q9UJS0,P00846,P07602,P11182,Q13423,Q9NZJ7,P03886,P03915,P51571,P00403,Q9NPL8,Q8IUX1,Q9Y375,P11117 25 +Skin vesicle 0.3861165202653743 0.3329068514023733 0.7392045974905166 1.0 0.8916897343550525 11 P16615,P98194 2 +Abnormal circulating fatty acid anion concentration 0.3766127273192259 0.3321677289099824 0.7397626102139092 1.0 0.8921293137570515 13 Q9NUN5,P23786 2 +Bone pain 0.3191007249122207 0.3306376046256816 0.7409182379149093 1.0 0.8925885595586672 22 Q9NZJ7,P35670,P07602,Q14108,Q9Y2U8 5 +Cns hypomyelination 0.285714823931292 0.3302688453770728 0.7411968312013759 1.0 0.8926907993141506 41 O75746,Q9Y2B2,Q8TB36,P51572,Q5T8D3,P49770,Q9NR50,P00387,O00400,Q5BJH7 10 +Prenatal maternal abnormality 0.3536504566108489 0.3293233900910515 0.7419112665226031 1.0 0.8933177727034636 16 O75665,P16435,Q8TAA9,P49366,P50416,Q14739 6 +Generalized muscle weakness 0.2918785627471563 0.3282798438369298 0.7427000827747456 1.0 0.8935670969780752 33 P21912,Q9NQ11,Q68CQ7,Q15165,P12235 5 +Hypodontia 0.2805487920834582 0.3273822099389398 0.7433788201869298 1.0 0.8939353906061634 45 Q9Y2B2,O75431,O95202,Q9Y4P3,O75844,Q9Y2U8 6 +Abnormal sputum 0.3912506551852887 0.3273618894101593 0.7433941876742227 1.0 0.8939353906061634 8 O75665,Q9NZ08 2 +Cerebellar malformation 0.264376516937347 0.3261809392437624 0.7442874617379296 1.0 0.8944537458920466 69 O75665,Q96J42,P23786,Q9UID3,P16435,Q8TAA9,Q9Y4P3,O60566,Q15043,Q14118,Q969G3,O43505,Q9Y487,O75845,Q15645,Q12768,Q8NAT1,Q15125,Q2M1P5,Q9Y2U8 20 +Dermal translucency 0.3890064969655176 0.3255050464722736 0.7447988638760414 1.0 0.8946906060325336 9 O75844,Q6NUK1 2 +Abnormality iris morphology 0.2710589675292617 0.3205787268175936 0.7485296609379386 1.0 0.8982355931255263 86 P21912,P40855,Q8NAT1,Q05086,O95202,Q9NR77,Q7LGA3,Q9Y4P3,Q96J42,O75381,Q14118,Q8N6S5,Q9UHX1,Q10713 14 +Rib fusion 0.3874874853901489 0.3178750763837649 0.7505796989569995 1.0 0.899640188573446 9 O95202 1 +Ventricular fibrillation 0.3922953817640758 0.3171570924397373 0.7511244057213666 1.0 0.8996626477901764 6 Q9HD47 1 +Abnormality of the supraorbital ridges 0.3226077395479928 0.3149260119475595 0.7528178310901306 1.0 0.9005671250423992 21 P16435,P40855,O75381,P56589,Q6PGP7,Q6NUK1 6 +Chronic hepatic failure 0.3685521111479491 0.3122424834161178 0.7548562477948186 1.0 0.9025138770700214 4 Q10713 1 +Ineffective esophageal peristalsis 0.3798044549842806 0.312167475714038 0.7549132484906411 1.0 0.9025138770700214 5 Q9NRG9,P06280 2 +Hemiplegia hemiparesis 0.2814535003231013 0.3109493601905218 0.7558391191593756 1.0 0.9025138770700214 43 Q8NBM4,O60313,Q9NZ08,P50416,P03886,P03915,P00403 7 +Abnormal acetabulum morphology 0.3274432379608511 0.3105357943862214 0.7561535439184945 1.0 0.9025138770700214 20 Q96L58,Q969X5,Q9Y584,Q8WVQ1 4 +Bilateral talipes equinovarus 0.3894017917175552 0.3102416625789526 0.7563771902783407 1.0 0.9025138770700214 7 Q15125 1 +Abnormality of lower limb epiphysis morphology 0.3504763893148872 0.3102067016337322 0.7564037745756125 1.0 0.9025138770700214 16 Q7LGA3,Q8WVQ1 2 +Meningioma 0.3856699586672929 0.3087856857420912 0.757484558524915 1.0 0.9035271177265238 9 P21912,Q969G3 2 +Gait imbalance 0.3216879960415939 0.3085628189563977 0.7576541076939982 1.0 0.9035271177265238 21 Q05086,Q9NR77,O43464,O94905,Q9Y4P3,O15269,Q9UBB4 7 +Ectopic anus 0.3372843790630905 0.3076596321030709 0.7583413396078551 1.0 0.90388952222271 18 Q9Y2B2,P53701,P16435,Q6NUK1 4 +Echolalia 0.3787330814106785 0.3068206531776846 0.7589798870374735 1.0 0.9040524054272606 12 O75787,Q9NX14,P53701,Q9UHX1 4 +Spasticity 0.2584889884502429 0.3049794698433447 0.7603817886041189 1.0 0.9050618618054008 320 Q8N183,P04062,Q5XKP0,Q9Y276,O75298,P00846,Q15043,P51648,Q5BJH7,Q9HCC0,Q6ZXV5,O95169,O94905,P17900,Q9NR50,Q9HA77,Q9Y619,O75503,Q9H6K4,P50897,Q68CQ7,Q15165,Q9UBB4,O75746,P56589,P49366,Q15907,P07602,Q8N2K0,P09622,Q96AA3,P56556,Q9H078,Q9NZJ7,O43505,O60313,Q9Y487,O60762,P16278,O43292,P03886,Q15041,Q9UBX3,Q12768,Q9Y320,Q2M389,O43464,Q96DA6,P52732,Q9UI09,Q15392,P21912,P40855,O43819,O43681,Q9NVI7,Q96CU9,Q9P0J0,Q9Y4P3,Q7KZN9,Q13510,Q96N66,O75477,O75381,O00400,O75787,Q01105,Q6DKK2,P07196,Q10713,Q2TAA5,Q3ZCQ8,Q9H490,P49770,P00387,Q86XL3,Q9NQ11,P03915,O15118,O95140,Q8NBU5,P11117 82 +Progressive muscle weakness 0.3714015310120711 0.3037131102785422 0.7613464689834997 1.0 0.9050618618054008 13 O75381,P40855,P56589 3 +Proximal upper limb amyotrophy 0.3863035262646069 0.3030329524221227 0.7618647491431509 1.0 0.9050618618054008 8 Q9BTV4,P50402,P02545 3 +Abnormality of the musculature of the upper arm 0.3863035262646069 0.3030329524221227 0.7618647491431509 1.0 0.9050618618054008 8 Q9BTV4,P50402,P02545 3 +Increased urine alpha ketoglutarate concentration 0.3778875150668362 0.3029526881444264 0.7619259175595223 1.0 0.9050618618054008 5 P21912 1 +Loss of ability to walk 0.3637933629862246 0.3005289306483619 0.7637737322401836 1.0 0.9068460082872368 14 P00846 1 +Abnormal circulating igg level 0.3408777396996095 0.3001178775611952 0.7640872430810008 1.0 0.9069576001661966 17 P00813 1 +Abnormal oral frenulum morphology 0.3403892434475012 0.2971011679437115 0.7663892727192598 1.0 0.9089256155015172 17 O43924,O75844 2 +Abnormal subcutaneous fat tissue distribution 0.3652538903377167 0.2961615190250078 0.7671067346238618 1.0 0.9091635373319844 4 Q9Y487 1 +Infantile axial hypotonia 0.3789724592863929 0.2958355922915111 0.7673556402176287 1.0 0.9092246824692294 11 Q9NZJ7,Q15043,P07602 3 +Nausea and vomiting 0.265526311426266 0.2948101223701163 0.7681389333985349 1.0 0.9099188187918892 154 Q8N183,P21912,Q86Y39,Q9NZ08,O96000,Q9NX14,Q9Y584,Q9Y6M9,P23786,O43676,Q2TAA5,P22695,Q96CU9,Q9UJS0,P00846,Q9Y4P3,P07602,Q969G3,P11182,P42892,Q9HCC0,Q13423,Q8IZA0,Q9NZJ7,P03886,Q02978,P03915,P51571,P00403,Q8NBM4,Q9NPL8,Q8IUX1,Q68CQ7,Q15165,Q9Y375,P11117 36 +Proximal muscle weakness in lower limbs 0.3248885675000995 0.2934226926744194 0.7691990821597929 1.0 0.9107064158767538 20 P50402,P12235,P35670,P07196 4 +Polycystic kidney dysplasia 0.3550787921671186 0.2924858425842711 0.7699151828549251 1.0 0.9113201034152312 15 P21964,P23786 2 +Fasciculations 0.2844996980051939 0.2920901394951948 0.7702177056594559 1.0 0.9114440646324532 38 Q9NZJ7,Q9BQT8,P07602,Q969X5,O43819,Q13510,P07196 7 +Gastroparesis 0.3836295921999223 0.2900194447960025 0.7718013618085995 1.0 0.9129313938464566 8 P12235 1 +Telecanthus 0.2793080949789704 0.2899286618969095 0.7718708138944868 1.0 0.9129313938464566 43 O75665,Q15125,Q86XL3,Q8NCH0,Q9H490,O75844,P21964 7 +Eeg with spike wave complexes 0.3468864362504279 0.2887887444475134 0.7727430459386071 1.0 0.9137284977380296 16 Q9Y2B2,P53007,Q9NQZ5,Q14108 4 +Occipital encephalocele 0.3862209501307098 0.2885023942002462 0.7729621980835191 1.0 0.913753157713919 6 Q6ZXV5,Q10713 2 +Multiple cafe au lait spots 0.3750267838463479 0.287395122814922 0.7738097951905574 1.0 0.91452052737576 12 P21912,Q8N6S5,O60566 3 +Rotary nystagmus 0.3632863967700063 0.2866455325445232 0.7743837467736432 1.0 0.91496418080332 4 Q5T8D3,O94905 2 +Thickened nuchal skin fold 0.3607268640663902 0.2834718929939498 0.7768151245417461 1.0 0.9171090721055898 14 O75381,P40855,Q15125 3 +Abnormal muscle fiber protein expression 0.3805099304791441 0.2832271302518962 0.7770027325106343 1.0 0.9171090721055898 9 P50402 1 +Abnormality of salivation 0.2748158910753796 0.2831886355331648 0.7770322394760396 1.0 0.9171090721055898 46 Q05086,P35670,Q9NR77,Q96RL7,O75787,Q68CQ7,Q15165 7 +Tissue ischemia 0.3006043160116443 0.28225654473813 0.7777468036515236 1.0 0.9171090721055898 24 O75844,Q9Y4P3,Q9NZ08,Q8NBM4 4 +Lymphoma 0.2874659005073358 0.2780427851999402 0.7809795152827639 1.0 0.9201620062446884 28 P60033,P00813 2 +Abnormality of mouth size 0.2609011965000114 0.2772048820651663 0.7816227911261948 1.0 0.9206845147007938 126 Q9Y2B2,O75665,Q05086,Q7LGA3,Q01105,P16435,Q9NVI7,Q9BUB7,Q9Y4P3,Q8WVQ1,Q9NX62,P21964,Q8NCH0,O75844,P51571,Q6NUK1,Q9UM00,O75431,Q15392 19 +Emphysema 0.3765522479468881 0.2729778171208811 0.7848702675817159 1.0 0.9237504036411196 10 P60033,Q03518,Q03519 3 +Myocardial fibrosis 0.3603959672209527 0.2727733198489638 0.785027469760986 1.0 0.9237504036411196 4 P13473 1 +Eeg with polyspike wave complexes 0.3797712652274022 0.2714186564820652 0.7860690546125302 1.0 0.9245038804631288 8 Q9Y2B2,Q14108 2 +Skeletal muscle atrophy 0.2683929838004744 0.2700453578336965 0.7871253588875635 1.0 0.925273891263748 173 P21912,Q9BQT8,Q9HC21,P50416,Q969X5,O43819,O15269,Q6DKK2,O75298,Q9NVI7,Q14118,Q13510,P12235,O75477,Q96RL7,O60313,Q13126,P13473,Q6P4A7,Q8NAT1,Q9NWM8,Q96DA6,Q9NPL8,P50402,Q68CQ7,O00400,Q15165,Q9Y2U8 28 +Hypercholesterolemia 0.3733815906743811 0.2673331538116261 0.7892126623039324 1.0 0.9270180851125466 11 Q9H9E3,O75431,Q8N511,Q9UJS0,Q15904,P02545 6 +Specific learning disability 0.2590775213807163 0.266217509014624 0.7900716991974845 1.0 0.9277255174154814 68 Q8NAT1,Q96DF8,P53701,Q9H6K4,O75845,Q8TC12,Q14118,P03886,Q9NX14,P03915,P21964,Q9Y2U8,P00403,Q10713 14 +Abnormality of hair texture 0.261796101193065 0.2648966162018812 0.7910891051298368 1.0 0.9282756802745832 53 Q9Y2B2,Q9NVI7,Q15125,Q96A33,O75844,Q6NUK1,Q9UM00 7 +Osteolysis 0.2856606468709622 0.2643592535496919 0.7915031059110225 1.0 0.9282932095517632 29 Q9Y2B2,P04062,O75431,Q96JJ3,O60566,Q14108,O75844 7 +Abnormality of circulating enzyme level 0.2686665511858083 0.263165554113721 0.7924229791003661 1.0 0.928894705595138 97 P09493,Q8NAT1,Q9NWM8,Q96RL7,Q9Y4P3,P50416,Q969X5,P50402,P42167,Q14118,P13473,Q9Y584,P23786,P12235 14 +Aspiration pneumonia 0.2856092185029212 0.2628162894380522 0.7926921796253512 1.0 0.9289561438760172 26 O95721,P20700,P04062,P16278,P06753,P21281,P78318,Q969G3,Q13510,Q6NUK1 10 +Hemoptysis 0.3804763874555015 0.2618668051523756 0.7934241324382791 1.0 0.9293590244726972 6 Q9NZ08 1 +Decreased muscle mass 0.3250827319813162 0.261278441740446 0.7938777903065073 1.0 0.9294179008466428 19 Q8TAA9,O95202,Q8NCH0,Q9Y487,P36543 5 +Prematurely aged appearance 0.2816946622391836 0.2597361315544235 0.7950673199184926 1.0 0.9302550378125164 37 O75844,Q13126,Q9Y4P3,O75431 4 +Muscle fiber tubular inclusions 0.3427819988310818 0.2570229159684354 0.7971610827949653 1.0 0.9318412657329276 3 Q9Y5P6,O75340 2 +Single fiber emg abnormality 0.3427819988310818 0.2570229159684354 0.7971610827949653 1.0 0.9318412657329276 3 Q9Y5P6,O75340 2 +Onychogryposis 0.3424897720631246 0.2556076879174749 0.798253781472418 1.0 0.932786578509545 3 P53634,Q9Y6K9 2 +Maturity onset diabetes of the young 0.3280747881974913 0.2536253753709331 0.7997849907812349 1.0 0.9337241544261794 2 P61457 1 +Subependymal cysts 0.3280747881974828 0.2536253753708914 0.7997849907812671 1.0 0.9337241544261794 2 Q9BSJ2 1 +Hepatocellular adenoma 0.3280747881974799 0.2536253753708771 0.7997849907812782 1.0 0.9337241544261794 2 P10644 1 +Aplasia hypoplasia of the distal phalanges of the hand 0.2825392005178287 0.2514974551868317 0.8014295294490408 1.0 0.9354071103599746 34 Q9Y2B2,Q9H9E3,P16435,Q96S52,Q9Y366,O75844,Q6NUK1 7 +Aortic regurgitation 0.2840541314351483 0.2504640651920917 0.8022284910363011 1.0 0.9358655409355128 28 Q9NZ08,O60566,Q6PGP7,P36543,Q15645,O75844,Q9UHX1,Q6ZXV5,Q8NBM4 9 +Slender long bone 0.361357713996641 0.2500409300967611 0.8025556960692342 1.0 0.9360102878985146 13 Q9Y619,Q96L58,Q9Y487,Q9H490,P37268,Q9H2M9 6 +Abnormality of the elbow 0.2585449379865412 0.2493838411805585 0.8030638832464139 1.0 0.936365985323754 54 Q96L58,Q9H6K4,Q7LGA3,Q8WVQ1,P37268,Q969X5,P50402,Q13510,P23786 9 +High pitched voice 0.3610673947491851 0.2485141263886466 0.8037366415632932 1.0 0.936913342859513 13 O75844 1 +Facial hemangioma 0.3774360469686373 0.2479627658837774 0.8041632157698664 1.0 0.9371735200474316 6 O75665,P16435 2 +Recurrent otitis media 0.2896116582654331 0.245331765141328 0.8061995581016483 1.0 0.9387141912049508 25 O75665,P00813,Q8N5M9,Q9H0U3 4 +Lipoatrophy 0.3123310870253292 0.2448457544463779 0.8065758649955821 1.0 0.9387141912049508 21 P42167,Q6NUK1,O75431 3 +Progressive inability to walk 0.3123261113743841 0.24481239675737 0.8066016947296073 1.0 0.9387141912049508 21 P21912,P00846 2 +Testicular atrophy 0.3654970760233871 0.2446757474620869 0.8067075080667547 1.0 0.9387141912049508 5 Q9NX24,P52788,P00492,O76024 4 +Abnormal ureter physiology 0.2721902447264436 0.2436373902299994 0.8075116674993748 1.0 0.9394127149298458 45 Q9Y2B2,P21912,P16435,Q8TAA9,Q9Y4P3,P21964,Q9UHX1 7 +Aplasia hypoplasia affecting bones of the axial skeleton 0.2708891509538813 0.2425547109371959 0.8083503689730749 1.0 0.9401510601282002 243 Q9Y2B2,Q96HY6,P40855,O75665,Q9HC21,Q7LGA3,Q96J42,O75787,P37268,Q969X5,Q9BT22,Q9UHX1,P16435,Q8TAA9,Q9NVI7,Q9BUB7,O95202,Q9Y4P3,Q8WVQ1,Q8N766,O60566,Q9NX62,P21964,Q96AA3,P53701,Q86XL3,Q8NCH0,O75845,Q8TC12,Q14739,O43924,O75844,Q8N6S5,P51571,Q6NUK1,Q9UM00,O75431,Q15125,Q96L58,O75381,Q15392,Q9Y2U8 42 +Abnormal iris pigmentation 0.2950566389023201 0.2411964497122689 0.8094028624064447 1.0 0.9409001992857964 24 P40855,Q05086,Q9Y4P3 3 +Synostosis of joints 0.2788256265121539 0.2404712232143422 0.8099649693795119 1.0 0.9412501189736824 38 O75665,P16435,O95202,Q96L58,Q9Y4P3,Q8WVQ1,Q9UHX1 7 +Abnormal conjugate eye movement 0.255868290856197 0.240281021065496 0.810112407085422 1.0 0.9412501189736824 321 Q9Y2B2,O75665,Q86Y39,P40855,Q05086,Q9Y375,Q8N183,Q7LGA3,Q96RT7,O96000,Q9BT22,Q9H061,O43819,Q9UHX1,Q9Y6M9,Q10713,O43676,O95470,P16435,Q2TAA5,Q9NVI7,O95202,Q96CU9,Q9P0J0,Q9Y4P3,Q15907,P07602,Q8N766,Q7KZN9,Q9H490,P00387,P21964,P12235,Q9NZJ7,P51572,Q96RL7,O60313,Q8NCH0,Q53H12,Q9NQ11,Q14739,O75027,P03886,O43924,P51571,Q6NUK1,Q9UM00,O15118,Q9NPL8,O75381,Q8IUX1,Q15392,Q9Y2U8 53 +Limited elbow extension 0.369060245712654 0.2361190845210163 0.813340265266485 1.0 0.9442862036653976 10 Q96L58,Q9H6K4 2 +Cystic hygroma 0.3721616272136487 0.235381806904237 0.8139124054261884 1.0 0.9447124343082812 8 Q96S52 1 +Tall stature 0.2551490082293301 0.2325866556998069 0.81608239037766 1.0 0.94675419306653 55 Q9Y2B2,P16435,O95202,Q3ZCQ8,Q9NWM8,Q7LGA3,Q8NCH0 7 +Spina bifida 0.2785257652348725 0.2314701353055527 0.8169495840616183 1.0 0.9475216922617512 37 O75665,Q9HC21,Q9Y4P3,O75845,P21964,Q9UHX1,Q10713 7 +Abnormal upper limb bone morphology 0.2663027925407986 0.229379498786293 0.8185739690103282 1.0 0.9489753066406568 96 O75665,P16435,Q9H9E3,O75431,O95202,Q96L58,Q7LGA3,Q9Y4P3,Q8WVQ1,Q96S52,O00116,Q14739,Q9NX62,O43924,O75844,Q9UHX1,Q6NUK1 17 +Abnormality of fibula morphology 0.3573948521190083 0.2293270040637573 0.8186147664706187 1.0 0.9489753066406568 13 Q96HY6,Q8WVQ1,O75431 3 +Gait disturbance 0.2554987214955753 0.2280265584957203 0.8196255936607795 1.0 0.9497813785280595 331 O14949,Q9Y2B2,P21912,Q05086,O75665,P04062,Q8TB36,Q9BQT8,Q9HC21,Q7LGA3,Q9NZ08,P05067,O75787,O14773,O43819,O15269,O43681,P07196,Q10713,Q5XKP0,P53007,O75298,Q9NVI7,Q5T8D3,Q96CU9,P00846,Q9Y4P3,Q15907,P07602,Q8WVQ1,Q8N766,P49770,Q15043,Q14108,Q14118,Q13510,P05023,P12235,Q9NZJ7,Q96N66,P35670,O75477,Q9NR77,Q96RL7,O60313,Q9NQ11,O43292,P03886,O43924,P13473,O75844,P03915,Q15041,P00403,Q8NBM4,Q8IV08,Q9H6K4,Q96S52,O15118,O95140,P50402,O00400,Q8NBU5 63 +Abnormality of the ribs 0.2533134080217075 0.2279021131023772 0.8197223399318778 1.0 0.9497813785280595 64 Q96HY6,P16435,P54802,Q9Y619,Q8TAA9,Q9UM00,O75431,O95202,Q96L58,P00813,P16278,Q14739,O75844,Q93063,Q9UHX1,Q12768,Q15738 17 +Abnormal scrotal rugation 0.3222319602687664 0.2249749683655478 0.8219987474665338 1.0 0.951940243359082 2 Q9UNW1 1 +Polycystic liver disease 0.3496053785442793 0.2221897330648487 0.8241661862035021 1.0 0.9534917865994856 4 P14314,Q9UGP8,Q9UBS4 3 +Pituitary growth hormone cell adenoma 0.3496053785442785 0.222189733064845 0.824166186203505 1.0 0.9534917865994856 4 Q9UBS4,O00170,P10644 3 +Kinetic tremor 0.2780633947380865 0.2172106251450143 0.8280442046841283 1.0 0.957737875297305 35 Q9NZJ7,P07602,O75027,Q14108,O43681 5 +Gangrene 0.3612193508448295 0.2169202205840734 0.828270519027706 1.0 0.95775923505136 12 Q8NBM4,P52732,Q9NZ08,P10644 4 +Abnormal sternum morphology 0.2614141442321357 0.2166163376200202 0.8285073524515143 1.0 0.9577927446303508 118 Q9Y2B2,P21912,P04062,Q96A33,Q7LGA3,Q9Y366,Q9UHX1,Q9NVI7,O95202,Q9Y4P3,Q9H490,O60566,Q13510,Q8NCH0,Q14739,Q9H9E3,O75431,Q96L58,Q96S52,P50402,Q96JJ3 21 +Horseshoe kidney 0.2705382330354589 0.2158271534035009 0.829122481742901 1.0 0.9582634551972128 44 Q8NCH0,O75845,P51571,Q9UHX1,Q9Y2U8 5 +Abnormality of the lens 0.2701769105091638 0.2133054969378185 0.8310886862807696 1.0 0.9602950517506988 223 P21912,P40855,O75665,Q7LGA3,Q9NZ08,Q96J42,P08670,Q96RT7,Q8WWY3,O76024,Q9NX14,P23786,Q10713,Q9Y276,Q9NVI7,Q9BUB7,Q9UJS0,Q9Y4P3,O60566,Q14118,P21964,P12235,Q03519,P53701,O60313,O75845,Q53H12,Q8TC12,Q13126,P03886,P03915,P00403,Q8NBM4,Q9H9E3,Q8NAT1,Q15125,Q96L58,Q9H6K4,O75381,O00400,Q96HR9,Q15800 42 +Abnormality of the spinal cord 0.2588817693854265 0.2124383599925083 0.8317650617203411 1.0 0.9608356491369596 75 O75665,Q8TAA9,O75298,Q9HC21,O95202,Q96L58,O95140,Q9Y4P3,O75845,O00400,P21964,Q9UHX1,Q9Y2U8,P07196,Q10713 15 +Dysmetric saccades 0.3680926665891248 0.2107736566438704 0.8330638957012964 1.0 0.9618537788503064 7 O14773 1 +Sudden death 0.2786300379406012 0.2099102752367884 0.8337377024148935 1.0 0.9623906144107788 31 P50402,P50416,Q96DA6 3 +Abnormal circulating dicarboxylic acid concentration 0.2708753551764339 0.2085644928746706 0.834788231533333 1.0 0.9633619260970696 43 P40855,P28288,Q9NUN5,P22695,Q96DA6,O75845,P37268,Q14739,P23786 9 +Aplasia hypoplasia of the phalanges of the hand 0.2529948042080184 0.2079915973690358 0.835235528218065 1.0 0.963636783682735 55 Q9Y2B2,Q9H9E3,P16435,Q96S52,Q9Y366,Q8WVQ1,Q14739,Q5JRA6,O75844,Q9UHX1,Q6NUK1 11 +Hemolytic anemia 0.2772879476732507 0.2066557558145928 0.8362787131769795 1.0 0.964598826112521 34 P60033,P22830,P00813,P09601 4 +Restrictive cardiomyopathy 0.3319696084161292 0.2057108552113982 0.8370167786770581 1.0 0.9650438014339912 3 O95235,Q969N2 2 +Abnormal urinary electrolyte concentration 0.306416893967475 0.2056256377022972 0.8370833494643366 1.0 0.9650438014339912 21 P35670,Q9Y4P3,P05023 3 +Aplasia hypoplasia of the hallux 0.3248364131438009 0.2035141572852143 0.8387331813064085 1.0 0.9667039768534093 17 Q9UHX1,Q7LGA3 2 +Hyperacusis 0.3635007328389623 0.201834095787349 0.840046425464507 1.0 0.9679754760041132 9 Q8NFV4,Q9Y4P3,P17900 3 +Abnormal left ventricular outflow tract morphology 0.344776862886933 0.2002146129343504 0.8413127390851947 1.0 0.9684997744596644 4 O60566 1 +Subvalvular aortic stenosis 0.344776862886933 0.2002146129343504 0.8413127390851947 1.0 0.9684997744596644 4 O60566 1 +Cranial nerve compression 0.363143720521721 0.2001770140369072 0.8413421434813446 1.0 0.9684997744596644 9 P21912 1 +Abnormality of the bladder 0.2563818308224768 0.197928055909682 0.843101352951622 1.0 0.9700402083398436 126 P21912,P04062,O76024,Q9UHX1,O43681,P07196,P16435,O75298,Q8TAA9,Q3ZCQ8,Q9UJS0,Q9Y4P3,P07602,Q969G3,P21964,P12235,Q9NZJ7,Q9NR77,Q86XL3,O94905,Q8NCH0,Q9NQ11,Q9NWM8,Q8N5K1,P50336,Q9UBB4 26 +Extramedullary hematopoiesis 0.3442001311366945 0.1976187386083694 0.8433433726449695 1.0 0.9700764506110884 4 Q14739 1 +Short foot 0.2770631467202293 0.1971556858299356 0.8437057075089578 1.0 0.9702510357377784 31 Q9Y2B2,Q96A33 2 +Abnormality of the anterior fontanelle 0.274583645865864 0.1967411954342611 0.8440300707816699 1.0 0.970381877784914 37 Q9H9E3,P16435,P40855,Q9Y619,P20674,Q15125,Q9Y487,O75381,P56589,Q2M1P5,Q6NUK1 11 +Somatic sensory dysfunction 0.2614935907586675 0.193219373125619 0.8467871670564082 1.0 0.973066151071304 114 P54802,Q8TB36,Q9NZ08,P05067,O14773,O43819,O15269,P07196,O75298,Q96BR5,P00846,P07602,Q9NZJ7,O00165,Q9NR77,Q96RL7,O94905,Q8NCH0,Q9NQ11,Q8NBM4,Q9Y619,Q8IV08,Q9H6K4,O95140,O00400,P50336 26 +Retinal perforation 0.3152205667543047 0.1915275002544004 0.8481123372326316 1.0 0.9738603663015116 2 P04439 1 +Epiretinal membrane 0.3152205667543047 0.1915275002544004 0.8481123372326316 1.0 0.9738603663015116 2 P04439 1 +Skin erosion 0.3607442970378834 0.1890989008347337 0.8500153029517601 1.0 0.9758023208773569 9 O75844,Q8N6S5,P50336,P98194 4 +Bradycardia 0.3489538066235654 0.1861674895007098 0.852313417867375 1.0 0.9778252819664558 13 O75880,Q9BTV4,P47985,Q6PJG6,O43464,O75208,P02545 7 +Childhood onset 0.2743881876857498 0.1858147288717198 0.8525900537167379 1.0 0.9778252819664558 35 P22830,P50402,O75431 3 +Abnormality of hair pigmentation 0.2929116208288485 0.1857782032939135 0.8526186982112447 1.0 0.9778252819664558 23 Q05086,Q13126,Q9UM00 3 +Abnormal circulating metabolite concentration 0.2526226350575429 0.1857614024672691 0.8526318740074776 1.0 0.9778252819664558 365 Q8N183,P21912,Q86Y39,P40855,P28288,P49257,P05067,O96000,P50416,P37268,Q969X5,Q9BT22,Q9NX14,O43819,Q9Y584,Q9Y6M9,P23786,P07196,P14174,Q5XKP0,O43676,O95470,Q9Y276,Q9NVI7,P22695,Q9BUB7,Q96CU9,Q9P0J0,P00846,Q9Y4P3,O14874,P07602,Q9UJS0,P42167,Q15043,Q14118,P11182,P22830,P21964,Q9HCC0,P05023,P12235,Q13423,Q6ZXV5,Q9NZJ7,P20674,P35670,Q96RL7,Q8N511,Q70HW3,O75845,Q14739,P03886,P13473,O75844,P03915,P08574,O75880,Q9H9E3,Q8NAT1,Q9NUN5,O75431,Q15125,Q9NWM8,Q96DA6,Q96D53,Q9NPL8,O75381,P50402,Q8IUX1,Q9BWD1,Q15392,O00400,Q15800,Q9Y375,P09493 76 +Downturned corners of mouth 0.270266507108639 0.1848220905563314 0.8533685805936615 1.0 0.9781896565610926 41 Q9Y2B2,O95202,Q96A33,O75845,Q9Y2U8 5 +Tongue fasciculations 0.353613821121856 0.1795183269284157 0.8575307282671325 1.0 0.9824718040415082 12 Q9BQT8 1 +Abnormal connection of the cardiac segments 0.2444505805244997 0.1782303839136398 0.8585420488114228 1.0 0.9833859708980952 58 Q9Y2B2,P40855,Q9Y4P3,O75844,P21964,Q9UHX1 6 +Decreased circulating antibody level 0.2663092173053387 0.175218352384189 0.8609080642904852 1.0 0.9856060522361628 44 P60033,P00813,Q9UJS0,P09601,O75787,Q8N5K1,P14174,Q9H0U3 8 +Abnormal ldl cholesterol concentration 0.3404535570593796 0.1749134982774157 0.8611476036941978 1.0 0.9856354092952966 14 P50402,P37268,Q8N511,Q15800 4 +Highly arched eyebrow 0.2464535437578743 0.1722218700740551 0.863263104928534 1.0 0.9875766759235962 61 Q9Y2B2,O75665,O95202,Q7LGA3,Q96S52,O43924,Q9UHX1,Q9UM00 8 +Craniosynostosis 0.2670286343336745 0.1722101481341097 0.8632723200130741 1.0 0.9875766759235962 43 Q96L58,Q8NCH0,Q9Y2U8,Q9NX62,P21964,Q6NUK1,Q9UM00 7 +Short femur 0.3490953882096786 0.1713827248008761 0.8639228374260379 1.0 0.9879036176840118 5 Q9UHX1 1 +Urinary incontinence 0.2596225993407708 0.1713012624287417 0.8639868878616683 1.0 0.9879036176840118 49 Q9NP73,Q9NZJ7,O75298,Q8TAA9,Q3ZCQ8,Q9UBB4,P07602,Q9NQ11,Q969G3,Q12768,P07196,O43681 12 +Patchy hypopigmentation of hair 0.3381641232422183 0.170835404524994 0.8643531894885856 1.0 0.9880772754064506 4 Q9UM00 1 +Depressed nasal ridge 0.2959315598367388 0.1705379054167349 0.8645871267355942 1.0 0.9880995734121076 22 Q9Y2B2,O95721,P10644,Q96J42,P16278,O60566,Q6PGP7,Q15645 8 +Pedal edema 0.358676634090308 0.1691423855642904 0.8656846463426189 1.0 0.9888633739084748 7 Q14108 1 +Apraxia 0.2519795904289023 0.1686272944759674 0.8660898101093104 1.0 0.9890810024742758 69 Q9Y2B2,P04062,Q05086,O96008,Q7LGA3,O75787,O14773,Q9NQ11,O43292,O43924,Q6DKK2,Q10713 12 +Elevated circulating follicle stimulating hormone level 0.3375305405792067 0.1680657629093682 0.8665315434280272 1.0 0.9893402755491448 4 P16435 1 +Hypotension 0.2733179774332919 0.1667173181093171 0.8675924783680089 1.0 0.9900840749708067 27 P04062,Q9NZJ7,P49366,P07602,O43681,Q13423 6 +Flared metaphysis 0.3558196003616243 0.166691571685137 0.8676127375720741 1.0 0.9900840749708067 9 Q96HY6,Q14739,Q96L58 3 +Increased susceptibility to fractures 0.2492802407463903 0.1659843103491164 0.8681692974209816 1.0 0.9904739100064084 55 P16435,P35670,Q96L58,Q9Y5U9,O75845,Q14739,Q14108,Q13126,O15269,Q9Y2U8 10 +Abnormality of the carpal bones 0.3317445924873015 0.1634603484579907 0.8701559905497782 1.0 0.9924947535775688 15 Q96L58,Q8WVQ1,Q15125 3 +Abnormality of exocrine pancreas physiology 0.3043228111520886 0.1609986536468104 0.8720944610426045 1.0 0.9942135765671256 20 O75665,P09601,Q15904,P14174,Q9UHX1 5 +Emg myopathic abnormalities 0.2722653647256315 0.1578259562724433 0.8745939448410294 1.0 0.9965699549523896 30 P53007,Q9BTV4,P07196,P02545,P50402,P13473,P12235 7 +Severe muscular hypotonia 0.2719087316761387 0.1571274129402262 0.8751444335179897 1.0 0.9969506921263032 32 O75746,P53007,P40855,Q9NWS8,O43505,Q9NWM8,O75381,P56589,Q9HA77,Q01105,P02545 11 +Abnormal reflex 0.2513151203393551 0.1554259520359464 0.8764855259993809 1.0 0.9982316618401254 367 O14949,Q8N183,P04062,Q8TB36,Q8WWY3,P13073,Q5XKP0,P53007,Q9Y276,O75298,P00846,Q15043,Q9HCC0,P20674,O94905,P17900,Q9HA77,Q9Y619,O75503,Q9H6K4,P50402,Q96HR9,P50336,Q9UBB4,Q9Y2B2,O75746,P54802,Q9BQT8,Q15067,Q96IX5,O14773,P56589,Q9BT22,Q9NWS8,Q96BR5,P07602,Q8N2K0,Q8NI60,Q96AA3,P12235,Q9H078,Q9NZJ7,O43505,O60313,O60762,O75027,O43292,P03886,Q9Y3E5,Q15041,Q12768,Q9Y320,Q8NAT1,Q9BTV4,O43464,Q9UI09,O75208,P02545,P21912,P40855,Q05086,Q9NP73,P50416,P11166,P06753,Q9NP72,Q9NRG9,O43819,O15269,O43681,Q96CU9,Q9P0J0,Q9Y4P3,Q7KZN9,Q14118,Q13510,Q96N66,O75477,Q96RL7,O75381,O00400,O75665,Q9HC21,Q9Y5U9,Q9NZ08,O75787,Q969X5,Q6DKK2,P07196,Q10713,O95721,Q2TAA5,Q8TAA9,Q3ZCQ8,Q8N766,P05023,Q9NR77,Q86XL3,Q9NQ11,Q14739,P03915,Q8NBM4,Q9H9E3,O95140,Q8NBU5 105 +Bulbar palsy 0.3499958058813818 0.1537681491234382 0.8777925484223845 1.0 0.9992894235361188 11 P53007,O43681 2 +Fragile skin 0.3499806417697627 0.1536978240698834 0.8778480005369376 1.0 0.9992894235361188 11 Q8NCH0 1 +Decreased facial expression 0.271562381311883 0.1523205549004318 0.8789341136155602 1.0 1.0 30 P04062,Q05086,O75787,Q969X5,Q9NQ11,P12235 6 +Abnormal renal morphology 0.2617934847240729 0.1492229142641386 0.8813777394531517 1.0 1.0 278 Q9Y2B2,P21912,P40855,O75665,Q7LGA3,Q9NZ08,Q96J42,O76024,O43819,Q9UHX1,P23786,Q10713,O95470,P16435,Q8TAA9,P00813,P00846,Q9Y4P3,O60566,Q14108,P21964,P35670,P60033,Q9BYC5,Q86XL3,Q8NCH0,O75845,P03886,O43924,Q96I36,P03915,Q8N6S5,P51571,P00403,Q9NUN5,O75431,Q15125,Q96D53,O75381,Q15392,Q9Y2U8 41 +Generalized hyperpigmentation 0.3412246379402127 0.1478938919654248 0.8824265087033154 1.0 1.0 13 P51648 1 +Cutaneous abscess 0.3055799006719172 0.1473403185724114 0.8828634101168722 1.0 1.0 2 P53634 1 +Membranoproliferative glomerulonephritis 0.3055799006719171 0.1473403185724108 0.8828634101168726 1.0 1.0 2 Q03252 1 +Arterial thrombosis 0.3525061864652295 0.1467874967759145 0.8832997539058045 1.0 1.0 8 Q9NZ08 1 +Spontaneous hemolytic crises 0.3052877592754829 0.1460358197383826 0.8838931114732624 1.0 1.0 2 P11166 1 +Motor axonal neuropathy 0.3217143662331069 0.1457649858567748 0.8841069178514256 1.0 1.0 16 O60313 1 +Acute lymphoblastic leukemia 0.3279760551934704 0.1437057707149643 0.885732814131327 1.0 1.0 15 Q9Y2B2,O60566,O00165 3 +Vertical supranuclear gaze palsy 0.3457220593590625 0.1419022219965522 0.8871572391806648 1.0 1.0 12 Q96RL7,Q9NQ11 2 +Corpus callosum atrophy 0.327428265219168 0.1408623639441312 0.887978674846676 1.0 1.0 15 P51572,O75503,O60313,Q8N766,Q9H9P8,P51970 6 +Abnormal male reproductive system physiology 0.2644893665301969 0.1400227141972213 0.8886420438504157 1.0 1.0 42 O75665,P16435,P04062,O75298,Q9Y4P3,O76024,Q8N5K1,Q13423 8 +Absent toe 0.3051682743397537 0.1386958199271761 0.8896905213893231 1.0 1.0 19 Q9UHX1,Q7LGA3 2 +Functional abnormality of male internal genitalia 0.2697267145812228 0.138563919441802 0.889794756316401 1.0 1.0 31 O75665,P16435,Q9Y4P3,O76024,Q8N5K1,Q13423 6 +Aplasia hypoplasia of the cerebellar vermis 0.2554892313926705 0.1368042328357367 0.8911855377850557 1.0 1.0 80 O75665,Q8NAT1,Q15125,Q9HC21,Q10713,Q15907,Q96J42,Q9H490,Q14118,O43924,P23786,Q6NUK1,Q9UM00 13 +Telangiectasia of the skin 0.3002982549955263 0.136369996792676 0.891528791162413 1.0 1.0 20 Q96JJ3,Q8IZA0,Q8N6S5 3 +Stillbirth 0.344490376605049 0.136147911130157 0.8917043525149146 1.0 1.0 12 P16435,P04062,Q14739,O75844 4 +Macular atrophy 0.3507921811175442 0.1355323750202507 0.89219096883613 1.0 1.0 7 P04062 1 +Overriding aorta 0.3472952884938183 0.1345868978171824 0.892938501375256 1.0 1.0 10 P53701,Q9Y4P3 2 +Cerebellar hypoplasia 0.2508492237381385 0.134549071372557 0.8929684104766147 1.0 1.0 134 O75665,Q9HC21,Q9Y5U9,Q96J42,Q96RT7,P23786,Q10713,Q5XKP0,Q9NVI7,P00374,Q15907,Q9H490,Q14118,O43292,O43924,Q6NUK1,Q9UM00,Q8NAT1,Q15125 19 +Arachnodactyly 0.2685475010801072 0.1340653437257739 0.8933509039001923 1.0 1.0 34 O95202,P21964,Q96L58,Q8NCH0 4 +Abnormal proportion of cd4 positive t cells 0.350193837547243 0.1330309360005911 0.8941689145423088 1.0 1.0 7 Q9H0U3 1 +Plagiocephaly 0.2680327965606999 0.1326447441360927 0.8944743443528949 1.0 1.0 35 Q9Y2B2,Q96L58,Q96A33,Q969X5,Q01105 5 +Hypersplenism 0.3480611203603354 0.1323383881259225 0.8947166450472699 1.0 1.0 9 P04062,Q9NZJ7,Q14108,P07602 4 +Bilateral ptosis 0.3118329107756228 0.1295012337956725 0.8969610487456245 1.0 1.0 17 Q5T8D3,O43819,O60313 3 +Subcutaneous nodule 0.3113974840404447 0.1270989144438866 0.8988621106433907 1.0 1.0 17 P21912,Q9Y2U8,Q13510,Q9NZ08 4 +Large hands 0.3440838022135141 0.1267118310520289 0.8991684814966949 1.0 1.0 11 Q9Y2B2 1 +Abnormal leukocyte physiology 0.2445959084121239 0.1214413911828447 0.9033414340464596 1.0 1.0 64 P04062,Q96DF8,P60033,P21964,P00813,Q9UJS0,P09601,O75787,Q14108,Q8N5K1,P14174,Q9H0U3 12 +Chorea 0.2583663676063635 0.1205784320431818 0.9040249529143058 1.0 1.0 93 Q5XKP0,Q9NZJ7,Q96N66,Q9H6K4,P00846,Q9P0J0,P07602,Q9BWD1,P03886,O43819,O43681 11 +Rimmed vacuoles 0.3295696210608873 0.1201318476500708 0.9043787042950472 1.0 1.0 14 Q9BTV4,P50402,P02545 3 +Abnormality of circulating adrenocorticotropin level 0.3407422843765472 0.118839461832954 0.9054025441766328 1.0 1.0 12 P16435,Q13423 2 +Abnormality of the upper respiratory tract 0.2590188057907034 0.1184407307421326 0.9057184544210028 1.0 1.0 100 Q96HY6,O75665,P16435,Q9NZJ7,Q03519,P60033,P21964,P00813,P07602,Q13510,Q14739,Q68CQ7,Q15165,Q9UHX1,Q9H0U3 15 +Increased muscle lipid content 0.3447071034110278 0.1178655843287226 0.9061741628476933 1.0 1.0 9 P06753,P23786,Q8NI60,Q9Y4W6 4 +Hamartoma of the eye 0.345602545158901 0.1173979719448765 0.9065446911138876 1.0 1.0 8 P21912 1 +Vasculitis 0.3401440869527001 0.1161057333512125 0.9075687449909036 1.0 1.0 12 P60033,Q9NZ08 2 +Abnormality of the calf 0.2408478035063132 0.1154161228122407 0.9081153002043568 1.0 1.0 60 Q96HY6,P16435,O75431,Q96L58,Q7LGA3,Q9Y4P3,Q8WVQ1,Q13126,Q9NX62 9 +Fasting hyperinsulinemia 0.3249349285659029 0.11475413796172 0.908640001430211 1.0 1.0 4 P02545,Q16836 2 +Macular thickening 0.3456631099411815 0.1143238643032127 0.908981065541667 1.0 1.0 7 Q96HR9 1 +Weakness of facial musculature 0.2403873413451668 0.1100089769943041 0.9124022555166644 1.0 1.0 60 P53007,P40855,Q9BQT8,O60313,P12235,O75381,Q15043,O43819,Q13510,Q9UHX1,P07196 11 +Genu varum 0.3401886804930601 0.1092945992967539 0.9129688300725154 1.0 1.0 11 Q96HY6,Q8WVQ1 2 +Impaired distal vibration sensation 0.3342105263157893 0.1092790831114453 0.9129811364858164 1.0 1.0 5 P20700,P54886,Q96RR1,P55072 4 +Congenital sensorineural hearing impairment 0.3449790035159578 0.1091944585936976 0.9130482554307902 1.0 1.0 6 Q16740 1 +Premature birth 0.2582330311331731 0.1088517831206071 0.9133200508039944 1.0 1.0 45 P40855,P04062,O43676,P49366,Q9BUB7,O75381,P56589,Q2M1P5,Q9NX14,O75844,P02545 11 +Athetosis 0.3146103534774047 0.1080726443979108 0.9139380676428246 1.0 1.0 16 O14949,Q96CU9 2 +Abnormality of the lymph nodes 0.2627811606582901 0.1051032185786794 0.9162939053955012 1.0 1.0 39 P60033,P00813,Q9NZ08,Q13510,P14174,Q9H0U3,Q8NBM4 7 +Abnormality of the posterior pituitary 0.3388996424676583 0.1036046950453996 0.9174830616108252 1.0 1.0 11 Q9UHX1,O76024 2 +Oculomotor nerve palsy 0.3428905792861338 0.103084919736344 0.9178955735636234 1.0 1.0 7 O00170,Q12824,Q99496,Q9UMX1,Q969G3,P31749 6 +Webbed neck 0.2639738899943391 0.099508106475387 0.9207348518103496 1.0 1.0 35 Q9Y2B2,O75844 2 +Facial asymmetry 0.2638579066333903 0.0963182884950107 0.9232677864979112 1.0 1.0 34 O75665,O95202,Q8NCH0,Q96JJ3,Q9UHX1 5 +Progressive cerebellar ataxia 0.2610870978496381 0.096024474167271 0.9235011348023114 1.0 1.0 40 Q8N183,Q9Y619,Q96CU9,Q9P0J0,Q9Y487,Q7KZN9,O14773,Q9NQ11,O76024,Q8NI60,Q9UBB4 11 +Abnormal clavicle morphology 0.2794204001841152 0.0958243534969144 0.9236600750666276 1.0 1.0 23 Q9Y2B2,Q9Y619,O75431,Q14739,O75844,Q15738 6 +Immunologic hypersensitivity 0.2640195557084327 0.0948904136181826 0.9244018709848684 1.0 1.0 32 P00813,Q9NZ08,Q5JRA6,P21964,Q9UID3,Q8NBM4 6 +Hip dislocation 0.2414453971627074 0.0931777323903729 0.9257623643940036 1.0 1.0 63 Q9Y2B2,O75665,P53007,O95202,Q96L58,Q96A33,Q9BYC5,Q9Y487,Q969X5,Q8NBU5,P36543,Q9Y3E5,O75844,Q9UHX1,P02545,Q15738 16 +Lactose intolerance 0.3056691992986596 0.0911908369495961 0.9273409556727898 1.0 1.0 3 Q14566,P42345 2 +Abnormality of lipoprotein cholesterol concentration 0.3109463179687267 0.0891637285146277 0.9289517909782294 1.0 1.0 16 P50402,P37268,Q8N511,Q15800 4 +Myopia 0.2563655145378983 0.0874529669509896 0.9303114690699208 1.0 1.0 108 P21912,Q05086,Q9NVI7,Q9NWM8,Q9Y4P3,Q8NCH0,Q8WVQ1,Q53H12,P51648,O43292,Q14118,O43819,Q9UHX1,P12235 14 +Sensory axonal neuropathy 0.3039298861510181 0.0867349476349923 0.9308821968870792 1.0 1.0 17 Q8IV08,Q9NQ11,O95140 3 +Thoracic kyphosis 0.3225425749656702 0.086266458416665 0.9312546013541564 1.0 1.0 14 P51648 1 +Acute coronary syndrome 0.2910043429331356 0.0813866017231664 0.9351345040382252 1.0 1.0 20 O75844,Q9Y4P3,Q9NZ08 3 +Abnormality of prenatal development or birth 0.2625026108795931 0.0804575017732957 0.9358733952825276 1.0 1.0 251 Q8N183,Q9Y2B2,P04062,Q86Y39,P40855,O75665,Q9HC21,Q7LGA3,Q96J42,O96000,P50416,Q969X5,Q9BT22,Q9NX14,Q9UHX1,Q9Y6M9,P23786,O43676,P16435,Q8TAA9,Q9NVI7,Q9BUB7,O95202,Q96CU9,Q9Y4P3,Q7KZN9,O60566,P21964,Q13510,Q9BYC5,O60313,Q70HW3,Q14739,P03886,Q96I36,O75844,Q6NUK1,Q9UM00,Q15125,Q96L58,O15118,Q96S52,Q9NPL8,O75381,Q8IUX1,Q9Y375 46 +Abnormal tricuspid valve morphology 0.3316615485835293 0.0782273525586936 0.9376472044862756 1.0 1.0 12 P53701,P21964 2 +Abnormal peripheral nervous system morphology 0.2564415051522676 0.0767915786789308 0.9387893501976344 1.0 1.0 165 P21912,P40855,Q9NP73,Q8TB36,Q9BQT8,Q15067,Q9HC21,Q96TA2,P02545,P56589,P06753,O76024,Q9BPX6,O43819,O15269,Q9UHX1,Q6DKK2,O43681,P07196,P53007,O95721,Q9NVI7,Q96BR5,P00846,P07602,Q8N2K0,Q15043,Q969G3,Q13510,P12235,Q9NZJ7,Q9NR77,Q96RL7,O60313,Q9NQ11,P03886,Q02978,Q9Y3E5,P03915,P00403,Q9Y619,Q8IV08,O95140,O75381,Q93063,Q9UBB4 46 +Male hypogonadism 0.3355094582407099 0.0762394574320527 0.9392285915303108 1.0 1.0 8 Q8N5K1 1 +Muscular dystrophy 0.2610061582005215 0.0742123995056445 0.9408413796803644 1.0 1.0 28 Q9BTV4,Q8NAT1,O43505,O60762,O14979,O60566,P50402,Q14118,Q15645,P02545 10 +Moderate global developmental delay 0.3326351228876416 0.0716286539818933 0.942897436058766 1.0 1.0 10 P21912 1 +Blue irides 0.3312634056043769 0.0706834747257168 0.943649673195885 1.0 1.0 11 Q05086 1 +Recurrent viral infections 0.3189350774211312 0.0693744260458784 0.9446915849222536 1.0 1.0 14 P00813 1 +Beaking of vertebral bodies 0.3335191460043523 0.0683903546211427 0.9454748997514428 1.0 1.0 8 Q9UM00 1 +Soft tissue sarcoma 0.2600329472562468 0.0662247481024584 0.947198893884288 1.0 1.0 34 P21912,O60566,Q13126,Q969G3,Q15392,Q96JJ3 6 +Peripheral pulmonary artery stenosis 0.3297519872761809 0.064331730986851 0.9487060881015814 1.0 1.0 11 Q9Y2B2 1 +Infantile muscular hypotonia 0.2455291995679462 0.0643127934426023 0.948721166850414 1.0 1.0 72 Q9Y2B2,O95169,Q05086,Q2TAA5,Q9NZJ7,P03886,P00846,P07602,Q15043,Q14118,Q969G3,P03915,O43819,Q13510 14 +Abnormal morphology of the conjunctival vasculature 0.3332171266514653 0.0639648811891559 0.9489981902699895 1.0 1.0 6 P06280,P10619,P18074 3 +Hypoplasia of the uterus 0.3304187175185106 0.0625383862337741 0.9501340939564152 1.0 1.0 10 Q16740,P53701 2 +Velopharyngeal insufficiency 0.3115779571028529 0.0621469477929168 0.950445810294298 1.0 1.0 4 Q96DF8,Q9BUF5 2 +Skin ulcer 0.2596666189241084 0.0616371199172983 0.9508518157083454 1.0 1.0 31 Q9Y2B2,P04062,Q8IZA0,Q03519,P52732,Q03518,Q14739,O15269 8 +Abnormal t cell morphology 0.3172483124327693 0.0615957007433203 0.9508848007530988 1.0 1.0 14 P00813,Q9H0U3 2 +Abnormal 5th finger morphology 0.2534281778998994 0.0583426064254265 0.9534757302734816 1.0 1.0 113 Q9Y2B2,O75665,Q05086,Q9Y366,Q96J42,Q9UHX1,Q10713,P13073,Q9Y4P3,Q8WVQ1,O60566,Q969G3,O75845,Q14739,Q15645,O43924,Q9UM00,Q9Y619,Q15125,Q96L58,Q96S52,Q5JRA6,Q9Y2U8 23 +Flushing 0.329880918560436 0.0568454393154839 0.9546683170952316 1.0 1.0 9 Q02978,P21912 2 +Sparse eyelashes 0.294054120969513 0.0540830274875618 0.9568690145579404 1.0 1.0 18 O75844,Q15125 2 +Asymmetric growth 0.3093873259155214 0.0515524393641548 0.9588853167994562 1.0 1.0 15 Q8N6S5 1 +Death in childhood 0.2624169099427752 0.0513157610021197 0.9590739091874674 1.0 1.0 25 Q9NPL8,P20674,O75431 3 +Broad palm 0.3294403977970002 0.0509391533279419 0.9593740061487068 1.0 1.0 7 O75665 1 +Stomatitis 0.2965039205459598 0.0482574530439145 0.9615110625747194 1.0 1.0 17 Q9NUN5,Q9NZ08 2 +Limited extraocular movements 0.3286829619043486 0.0481248503967374 0.9616167413947072 1.0 1.0 7 O95169,O43819 2 +Mask like facies 0.3195125957109608 0.0477058954682236 0.9619506355503676 1.0 1.0 13 O75787,Q9NQ11,Q05086 3 +Incomitant strabismus 0.3140865182530372 0.047225226769643 0.962333721894149 1.0 1.0 14 Q7LGA3 1 +Abnormal cranial nerve physiology 0.2445430207761993 0.0443040486913287 0.964662044456324 1.0 1.0 73 P21912,P40855,P53007,Q9NZJ7,Q9NR77,Q9NZ08,P12235,P07602,O75381,Q15043,O43819,Q13510,Q9UHX1,P07196,Q8NBM4 15 +Dysphagia 0.2475011233217604 0.0434828356094071 0.9653166467836792 1.0 1.0 139 Q8N183,P21912,P04062,Q05086,P05067,O76024,Q01105,O43819,Q9UHX1,P53007,P00846,P07602,Q14108,Q13510,P12235,O95169,Q8IZA0,Q9NZJ7,P35670,Q9NR77,Q96RL7,O60313,O94905,Q9NQ11,Q14739,P03886,P03915,O15118 28 +Autoimmunity 0.2569057948616362 0.0421184792425847 0.9664042489363878 1.0 1.0 34 P60033,P21964,P00813 3 +Limb girdle muscle atrophy 0.3126872453835659 0.0409547506574759 0.9673319693162992 1.0 1.0 14 Q9BTV4,P06753,P50402,Q14118,P02545 5 +Abnormal circulating sulfur amino acid concentration 0.3257059459897912 0.0405866264998596 0.967625445879505 1.0 1.0 9 Q9NUN5,Q9UJS0 2 +Decreased serum complement c3 0.2922267679719502 0.0392216242388452 0.9687136932501216 1.0 1.0 3 Q03252,Q6VY07 2 +Abnormal phalangeal joint morphology of the hand 0.2556196089093045 0.0378879956990438 0.969776984222524 1.0 1.0 37 Q9Y2B2,P16435,Q8WVQ1,O76024,O75844 5 +Abnormality of the cheek 0.2338940535663265 0.0349166088492791 0.9721462367419792 1.0 1.0 60 O75431,O95202,Q9Y5U9,P52732,Q9Y366,Q96J42,Q9Y487,O75845,O60762,Q96S52,Q2M1P5,Q96JJ3,Q93063,Q9UHX1,Q12768 15 +Anisocoria 0.3037925191152366 0.0335132196622562 0.97326532398804 1.0 1.0 4 Q9NR77 1 +Abnormal dentin morphology 0.3247561269685175 0.0333377491115947 0.9734052510416112 1.0 1.0 6 Q96L58 1 +Abnormality of the hallux 0.2412599229715776 0.0281622039240544 0.9775327821582424 1.0 1.0 52 Q15125,O95202,Q96L58,Q7LGA3,Q9Y4P3,Q8WVQ1,O95140,Q9UHX1 8 +Ulnar deviation of finger 0.323226810575303 0.0279806600175853 0.9776775761776562 1.0 1.0 6 Q96L58,Q9Y3E5 2 +Hoarse voice 0.2539847145334183 0.0272185560742503 0.9782854155816768 1.0 1.0 27 Q96HY6,Q9Y2U8,Q13510,Q9Y4P3 4 +Adrenal hypoplasia 0.3221672919551558 0.0271418185195099 0.9783466206796289 1.0 1.0 9 O75844,Q15738,Q12768 3 +Abnormal pulmonary interstitial morphology 0.2545057213999447 0.0249420179735727 0.9801012121517908 1.0 1.0 30 O75665,P04062,Q8IZA0,P09601,Q14108,Q13510 6 +Facial diplegia 0.3200046181201996 0.0247402196413617 0.98026217425418 1.0 1.0 11 P12235 1 +Orofacial dyskinesia 0.3218750206243209 0.0234427819455325 0.9812970793144762 1.0 1.0 7 Q96RL7,Q9BPX6 2 +Diffuse cerebellar atrophy 0.3214604144090393 0.021975878526364 0.9824671970381732 1.0 1.0 7 Q8N766 1 +Autism 0.2444348094373192 0.0209240801451552 0.9833062176493792 1.0 1.0 49 Q9Y2B2,P21912,Q05086,Q9Y4P3,O76024,P21964 6 +Microvesicular hepatic steatosis 0.3196231165283091 0.0199915657066165 0.9840501008134516 1.0 1.0 10 Q96DA6,Q9Y276 2 +Absent thumbnail 0.2999123063431682 0.0198311942984832 0.984178033321088 1.0 1.0 4 O14936,P21281,Q9H936 3 +Iris coloboma 0.2533998386980574 0.0181782589107469 0.98549664664724 1.0 1.0 36 Q8NAT1,O95202,P53701,Q14118,Q9UHX1,Q10713 6 +Pectus excavatum 0.2489019542948894 0.0169675161543076 0.9864625303936768 1.0 1.0 86 Q9Y2B2,P21912,P04062,Q9H9E3,O75431,Q96L58,Q96A33,Q7LGA3,Q9Y4P3,Q8NCH0,Q9H490,P50402,Q9UHX1 13 +Sideroblastic anemia 0.3176099779361157 0.0123865181354923 0.9901172411299816 1.0 1.0 10 O75027 1 +Adrenal insufficiency 0.2527520567251414 0.0114081287977247 0.9908978275993884 1.0 1.0 31 P16435,O95470,P40855,O75381,Q969G3,Q13423 6 +Cerebellar vermis atrophy 0.315591534023683 0.0076271505934577 0.9939144733012752 1.0 1.0 11 Q96S52 1 +Metaphyseal widening 0.2774898150691553 0.0067129482994409 0.994643882422162 1.0 1.0 20 Q96HY6,Q14739,Q96L58,Q8WVQ1 4 +Avascular necrosis 0.2692415038893692 0.0062844854296876 0.9949857391092528 1.0 1.0 22 P04062,Q9NZ08,Q14108,O75844,Q8NBM4 5 +Abnormal rib cage morphology 0.2442716421023246 0.0044430423271433 0.9964549767876782 1.0 1.0 78 Q96HY6,O75665,P16435,Q8TAA9,O75431,O95202,Q96L58,P00813,Q8WVQ1,O75844,Q9UHX1,Q9UM00 12 +Skin tags 0.2688066800168315 0.00383404578906 0.9969408815542924 1.0 1.0 22 O95202,Q96S52,Q2M1P5,Q9UHX1,Q12768 5 +Abnormal size of pituitary gland 0.3155893536121588 0.0020742464057007 0.9983449920043688 1.0 1.0 6 Q12824,Q99496,Q9UMX1,Q969G3,P31749 5 +Heteronymous hemianopia 0.3156816851960228 0.0019744312741798 0.9984246327935288 1.0 1.0 7 O00170,Q12824,Q99496,Q9UMX1,Q969G3,P31749 6 +Nonprogressive 0.3154792240979911 0.0012888661448933 0.9989716338867642 1.0 1.0 7 Q10713 1 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..61fb67a7b150610edf6d9161f3940e0ac2ee8944 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lacrimal punctum morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent lacrimal punctum", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of falx cerebri", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the bladder", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid apraxia", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Increased vldl cholesterol concentration", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intraventricular hemorrhage", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lip pit", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphadenitis", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megacystis", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple epiphyseal dysplasia", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orbital cyst", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skewfoot", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft lip", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABHD11", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG13", "ALG6", "ANAPC1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP1S1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARL6IP6", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCKDHA", "BCKDHB", "BCKDK", "BCS1L", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "CAD", "CALD1", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBX2", "CC2D1A", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CD3EAP", "CD81", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK6", "CDKN2A", "CELF2", "CENPF", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COASY", "COG4", "COG7", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COQ8B", "COQ9", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "COX6B1", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CTU2", "CUL3", "CUL4B", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DAG1", "DARS", "DARS2", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC19", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DPP9", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "FAH", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FUT8", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNAI3", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD2", "GPI", "GPKOW", "GRHPR", "GSDME", "GSR", "GSS", "GSTM3", "GTF2I", "GUF1", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HAX1", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IKBKG", "IMPA1", "IMPAD1", "IMPDH1", "INF2", "INTS1", "IRF2BP2", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ITCH", "ITGA6", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF7", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2L", "LMBRD1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "LUZP1", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED17", "MED23", "MED25", "MESD", "MFF", "MFN2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOCS2", "MOGS", "MORC2", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVK", "MYH14", "MYH9", "MYLK", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPH", "NCDN", "NCSTN", "ND1", "ND5", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NOVA2", "NPC1", "NPC2", "NPM1", "NR2F1", "NR3C1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OFD1", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PACS1", "PAFAH1B1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS1", "PDSS2", "PEPD", "PEX11B", "PEX14", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POMGNT2", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRSL1", "RAB11B", "RAB18", "RAB3GAP2", "RAB7A", "RAC1", "RAC3", "RAD21", "RAD50", "RALA", "RANBP2", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REEP6", "REPS1", "RFC1", "RFC2", "RFT1", "RINT1", "RMND1", "RNASEH2A", "RNASET2", "RNF2", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRP7A", "RTN2", "SAMHD1", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SEC23A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC2A1", "SLC30A9", "SLC33A1", "SLC39A14", "SLC9A3R1", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNIP1", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SRSF2", "SSBP1", "SSR4", "STAG1", "STAG2", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUFU", "SUZ12", "SYNE1", "SYNE2", "TAF15", "TALDO1", "TAOK1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D8B", "TBCD", "TBCE", "TBL2", "TCOF1", "TDP2", "TECR", "TELO2", "TENM3", "TERF2IP", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIA1", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TKFC", "TKT", "TMCO1", "TMEM106B", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TSFM", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP6", "TUFM", "TWNK", "TXNDC15", "TXNRD2", "UBA1", "UBAC2", "UBE3A", "UBE4A", "UBE4B", "UBIAD1", "UBR1", "UBR7", "UBTF", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13A", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR11", "WDR34", "WDR36", "WDR73", "WFS1", "WNK1", "XIAP", "XPNPEP3", "XRCC1", "XRCC4", "YARS", "YARS2", "YEATS2", "YIF1B", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF687", "ZPR1"], "leading_proteins": ["AAAS", "AAGAB", "ABCB7", "ABCD3", "ABHD11", "ABHD12", "ACAT2", "ACBD5", "ACOX1", "ACP2", "ADA", "AFG3L2", "AGK", "AGPS", "AIP", "AKT1", "AKT2", "ALDH18A1", "ALDH3A2", "ALG1", "ALG11", "ALG13", "ALG6", "ANKLE2", "ANO6", "AP1S1", "APOL2", "APP", "ARHGDIA", "ARL6IP1", "ARL6IP6", "ASAH1", "ASNA1", "ASPH", "ATAD1", "ATAD3A", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2C1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATXN10", "B3GALT6", "B4GAT1", "BANF1", "BCAP31", "BCKDHA", "BCKDK", "BCS1L", "BRAT1", "BUB1B", "C19orf70", "CANT1", "CARS2", "CASK", "CCDC47", "CD81", "CDK4", "CERS1", "CHST14", "CHUK", "CISD2", "CLCC1", "CLN5", "CLN6", "CLPB", "CLPP", "CNNM4", "COA3", "COA7", "COG4", "COMT", "COQ8A", "COQ8B", "COQ9", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPT1A", "CPT2", "CRTAP", "CTNND1", "CTSA", "CTSC", "CYB5R3", "CYC1", "CYFIP2", "DAG1", "DBT", "DCTN1", "DDRGK1", "DHCR24", "DHFR", "DHPS", "DIABLO", "DICER1", "DLD", "DNAJB11", "DNAJC19", "DNAJC3", "DOCK7", "DPM1", "DYNC2H1", "EBP", "ECE1", "EIF2B2", "EIF2B3", "ELMO2", "EMC1", "EMD", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "EWSR1", "EXOC8", "EXT2", "FAR1", "FDFT1", "FECH", "FKBP10", "FKBP14", "FLII", "FOXRED1", "FUS", "FUT8", "GAA", "GALNT2", "GBA", "GDAP1", "GGCX", "GLA", "GLB1", "GLMN", "GLT8D1", "GM2A", "GMPPB", "GNA11", "GNAI3", "GPAA1", "GSDME", "GYG1", "HADH", "HADHA", "HAX1", "HCCS", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMOX1", "HNRNPA2B1", "HNRNPDL", "HNRNPK", "HPRT1", "HS2ST1", "HTRA2", "IER3IP1", "IFT52", "IGBP1", "IKBKG", "IMPAD1", "JAGN1", "KIAA0319L", "KIF11", "KIF20A", "KIF7", "L2HGDH", "LAMP2", "LBR", "LEMD3", "LETM1", "LMAN1", "LMBRD1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRP1", "LRPAP1", "MAGT1", "MAPRE2", "MATR3", "MBOAT7", "MCCC2", "MCM6", "MCM7", "MESD", "MFN2", "MGME1", "MIA3", "MICU1", "MIF", "MINPP1", "MOCS2", "MRPL12", "MRPS16", "MRPS22", "MRPS28", "MRPS7", "MSMO1", "MTAP", "MTCH1", "MTOR", "MTX2", "NAGLU", "NCSTN", "ND1", "ND5", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA6", "NDUFA8", "NDUFAF1", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFS2", "NEFL", "NHP2", "NNT", "NONO", "NPC1", "NR3C1", "NSDHL", "NTHL1", "NUP85", "NUP88", "NUP93", "NXN", "OFD1", "OPA1", "OPA3", "P3H1", "P4HA2", "PACS1", "PCBD1", "PDCD6", "PDE6D", "PEX14", "PEX19", "PEX3", "PHB", "PHGDH", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PISD", "PITRM1", "PLD3", "PLOD1", "PMPCA", "PNPLA6", "POFUT1", "POMGNT2", "PON2", "POR", "PPOX", "PPP1R12A", "PPT1", "PREPL", "PRKAR1A", "PRKCSH", "PRKRA", "PRPF31", "PSAP", "PTPN1", "PTPRF", "PTRH2", "PUF60", "PXMP2", "QRSL1", "RAB11B", "RAB18", "RAB3GAP2", 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0000000000000000000000000000000000000000..5c6a9cbda942adf4ad7568e2a98a5382efd7dda1 --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,11 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Parkinsons disease 28 62 4.670635871843984 3.0026879378475257e-06 16.90776699029126 54.04126213592233 1.0315348591123816 0.3152611195514452 7.595108151251147 4.223805209268991 1.8494970521239744 0.3626807692210581 3.808803596722554e-13 5.301792220889015e-07 1.3900290333881474e-11 3.87568866146267e-13 4.209655523571093e-15 +Oxidative phosphorylation 27 67 4.34195476112601 1.4122061533505814e-05 18.79854368932039 59.0752427184466 1.0149760730411637 0.3252836463038503 7.263801581344288 4.652138947381941 1.8018345229041028 0.3643612228552857 1.9899609319531277e-11 9.028179583440972e-06 2.3243398294928067e-10 3.899494705041318e-11 3.3783827417536846e-14 +Huntingtons disease 26 86 3.7659733893193374 0.0001659014625867 19.631067961165048 76.91504854368932 0.635715043905642 0.4301008974270168 9.08454389027927 5.4148363920790175 1.5734816663041495 0.3870978376334237 1.170064279983824e-08 6.350388621618643e-06 1.5146780442990195e-09 2.935381633286923e-09 2.335108924271697e-09 +Alzheimers disease 23 67 3.741726107597141 0.0001827606397506 16.135922330097088 58.91990291262136 0.6161331149111849 0.4362889390372475 6.737157569069632 4.882193919366804 1.448905264905826 0.3805753751040122 4.438887834905155e-07 0.000407082511055 5.007652938134333e-07 6.550651408812998e-07 7.776186780780236e-08 +Cardiac muscle contraction 13 23 3.638454988011679 0.0002742785529721 7.728155339805825 19.856796116504853 1.0644813600437804 0.240240383706381 3.4195161605095614 1.765741250102918 1.6465694074711887 0.3002212677564749 4.769794726419592e-07 0.0012844156650938 4.066081157623494e-06 1.0512375529822254e-05 1.4003071160859037e-08 +Snare interactions in vesicular transport 12 18 3.055671036512691 0.0022455748450034 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 1.832875539522981e-05 0.1553991536419083 0.0045096021611559 0.001435579094649 3.935736579209363e-09 +Glycosylphosphatidylinositol gpi anchor biosynthesis 4 6 2.5802679428388684 0.0098723682616848 1.9587378640776696 4.70873786407767 0.4176743741172245 0.4507661015005149 1.320395042101828 1.4540273361912954 1.0433021436146148 0.313242671371663 0.0076703170263664 1.0 1.0 0.0693365470158766 0.0097510399506001 +Hypertrophic cardiomyopathy hcm 7 12 2.1661485278560213 0.0302998389295705 3.429611650485437 9.101941747572816 0.6486134300733651 0.4298239576137608 1.8675556020784376 1.719193792909202 1.0005513529453438 0.3180395638112931 0.1209936280624116 1.0 1.0 0.6437372861060551 0.1451121707049519 +Sphingolipid metabolism 6 12 2.1524944177123517 0.0313584344758379 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 0.0247128756640835 1.0 1.0 0.4587195489148998 0.0308662830144804 +N glycan biosynthesis 7 20 1.9839576440734847 0.0472605619248833 5.849514563106796 16.08252427184466 0.2628189875288922 0.4633396270200485 3.100528416799328 2.9026244296339763 1.1828065880862877 0.3297121354639235 0.0022075209587826 0.1795501084992132 0.327507803675052 0.016869226769582 0.0006746347610051 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bf1fef273754507272c26578e735c4ecde16b8d2 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 181, + "title": "Average number of proteins per term", + "value": 17.933701657458563 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2461975607dbe327ad81a09ccad20d95a3953de9 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ce72848b02bdc1ced764b158fefc8eb49313bad7 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,48 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Parkinsons disease 0.6586082584459015 4.6706358718439835 3.0026879378475257e-06 0.0005433396702241 0.0005434865167505 62 O14949,P21912,O95168,O96000,O14548,Q9UDW1,Q9Y6M9,P13073,O43676,P22695,O95139,P00846,P14406,P12236,P45880,P21796,Q9Y277,P12235,P20674,P05141,P03886,P03915,P08574,O95167,P00403,P24539,P06576,O14957 28 +Oxidative phosphorylation 0.6196367725756219 4.34195476112601 1.4122061533505814e-05 0.0025528471158896 0.0012780465687823 67 O14949,P21912,Q86Y39,O95168,P56385,O96000,O14548,Q9UDW1,Q9Y6M9,P13073,O43676,P22695,O95139,P00846,P14406,Q7KZN9,P20674,P03886,P03915,P08574,O75964,O95167,P00403,Q93050,P24539,P06576,O14957 27 +Huntingtons disease 0.5480596515174315 3.7659733893193374 0.0001659014625867 0.0295842158398041 0.0066159351589733 86 O14949,P21912,O95168,O96000,Q9UDW1,O14548,Q9Y6M9,P13073,O43676,P22695,P00846,O95139,P14406,P45880,P12236,P21796,P12235,Q9Y277,P20674,P05141,P08574,O95167,P00403,P24539,P06576,O14957 26 +Alzheimers disease 0.5567698489513118 3.741726107597141 0.0001827606397506 0.0325414515685928 0.0066159351589733 67 O14949,P21912,O95168,O96000,P16615,O14548,Q9UDW1,Q92542,Q9Y6M9,P13073,O43676,P22695,O95139,P00846,P14406,P20674,P08574,O95167,P00403,P14927,P24539,P06576,O14957 23 +Cardiac muscle contraction 0.7688917618632135 3.638454988011679 0.0002742785529721 0.0484387550043577 0.0082740696813259 23 O14949,P13073,P09493,P20674,P22695,P14406,P16615,O14957,O14548,P08574,P05023,Q9UDW1,P00403 13 +Snare interactions in vesicular transport 0.7552155346165624 3.055671036512691 0.0022455748450034 0.3342932942290919 0.0329347262491766 18 P56962,O95721,O15400,O43752,O95249,O60499,O15155,O75396,Q13190,Q9P2W9,Q12981,Q9UEU0 12 +Steroid hormone biosynthesis 0.8511723696082312 2.99813425549834 0.0027163798155367 0.3888016449408754 0.0329347262491766 3 P21964 1 +Glycosaminoglycan biosynthesis keratan sulfate 0.7931638913234087 2.853991173208527 0.0043173730865189 0.5430294323365826 0.0420622236805889 2 Q9BYC5 1 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.8222741888336866 2.723728513939502 0.0064549543307315 0.6902946298106061 0.0509068077521103 4 Q96L58,Q8NCH0,Q9P2E5 3 +Glycosaminoglycan biosynthesis heparan sulfate 0.7776154295733562 2.6391455405668194 0.0083115289992641 0.7792387515241956 0.0601754699546722 3 Q96L58,Q7LGA3 2 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.8316836691396299 2.5802679428388684 0.0098723682616848 0.8340016784745552 0.0687268713601903 6 Q9Y2B2,Q9H490,Q96S52,O43292 4 +Alpha linolenic acid metabolism 0.7600818234950383 2.551114970555676 0.010737889709856 0.8583035519221535 0.0719836310179236 3 Q15067,O95864 2 +Primary immunodeficiency 0.7757339082463506 2.4972338089985344 0.0125166398638874 0.8976963108648089 0.0781210970815041 4 P00813,Q03519 2 +Primary bile acid biosynthesis 0.6628688285130037 2.173372871489339 0.029752264922175 0.9957756741882908 0.1482235363851965 2 P22307 1 +Hypertrophic cardiomyopathy hcm 0.7030093738437582 2.1661485278560213 0.0302998389295705 0.9961859914492176 0.1482235363851965 12 P09493,P05556,P67936,P50402,P16615,Q14118,P02545 7 +Sphingolipid metabolism 0.7004902716053463 2.1524944177123513 0.0313584344758379 0.9968701659231776 0.1493651747401756 12 O95470,P04062,Q13510,Q9NRA0,O15269,O43681 6 +O glycan biosynthesis 0.7030156234147855 2.130170792381021 0.0331575154731769 0.9977644398771855 0.1538848795037184 4 Q10472,O43505 2 +Renin angiotensin system 0.681819952658005 2.0200883337680775 0.0433742257424096 0.9996731743835836 0.1825752292878174 4 P52888,P10619 2 +N glycan biosynthesis 0.5594600183504111 1.9839576440734852 0.0472605619248833 0.9998435700618412 0.1944127661000884 20 Q9Y673,Q86YN1,Q2TAA5,Q9BYC5,P46977,Q9BT22,Q96AA3 7 +Protein export 0.6201658958135474 1.9594059481559472 0.0500652646319359 0.999908257181004 0.196995932573487 15 Q15070,P67812,Q9Y5M8 3 +Dilated cardiomyopathy 0.6526311630851178 1.850945468661644 0.0641773985576974 0.9999938901732492 0.2323221827788647 11 P09493,P05556,P67936,P50402,P16615,Q14118,P02545 7 +Lysosome 0.3960218876741675 1.76897438675441 0.076898149057329 0.9999994869241854 0.2676647111418569 52 P54802,P04062,O14773,O43681,P07602,P11279,Q14108,Q13510,Q9NZJ7,Q9Y487,P17900,P13473,P10619,Q93050,O75503,Q9UMR5,O15118,P50897,Q15904,P11117 20 +Calcium signaling pathway 0.5337889133666207 1.665330897933673 0.0958467574142143 0.9999999879826144 0.2963794665382253 18 P12236,P45880,P16615,P21796,P12235,Q9Y277 6 +Porphyrin and chlorophyll metabolism 0.566292707168058 1.5445288732418037 0.1224602620917501 0.9999999999461372 0.351830276803282 14 P30519,P53701,P09601,Q7KZN9,P50336,P22830 6 +Ecm receptor interaction 0.5916403533547118 1.39444726106851 0.1631825848551003 0.99999999999999 0.4102228869274049 7 Q14118,Q08722 2 +Abc transporters 0.5782101261361843 1.3461898545822435 0.1782412961315134 0.9999999999999996 0.4187003607884175 8 P28288,P08183,Q03519,Q03518,O75027,P33527 6 +Biosynthesis of unsaturated fatty acids 0.5621492528117971 1.3394186859474404 0.180434409621528 0.9999999999999998 0.4187003607884175 11 O00767,Q6Y1H2,Q9BY49,Q53GQ0,O95864 5 +Ether lipid metabolism 0.5672546260433212 1.319931026694638 0.1868580474343772 1.0 0.4207500719301877 5 Q8NF37,O00116 2 +Steroid biosynthesis 0.5394880147310522 1.30585723323656 0.1916011125217207 1.0 0.4207500719301877 13 Q15125,Q14534,Q16850,O75845,P37268,Q15392,Q15800,Q15738 8 +Antigen processing and presentation 0.459701202055352 1.2100132916224682 0.2262737926634817 1.0 0.4488326652129736 19 P27824,P61289,Q03519,P30511,Q9UL46 5 +Proximal tubule bicarbonate reclamation 0.5520796021072538 1.2015237936759076 0.2295480824451305 1.0 0.4488326652129736 8 P05026,O94925,P54709,P05023,Q9UBX3 5 +Graft versus host disease 0.5307760552942622 1.1193529323278062 0.2629896023206715 1.0 0.4621467768936071 5 P30511 1 +Autoimmune thyroid disease 0.5307760552942622 1.1193529323278062 0.2629896023206715 1.0 0.4621467768936071 5 P30511 1 +Allograft rejection 0.5307760552942622 1.1193529323278062 0.2629896023206715 1.0 0.4621467768936071 5 P30511 1 +Glycerophospholipid metabolism 0.4390763812504566 1.0613068581199463 0.2885504700341945 1.0 0.4791526153778827 19 Q96N66,Q92604,Q643R3,O95674,Q9UG56,O14735,Q86UL3,Q8NF37 8 +Riboflavin metabolism 0.5172414453109164 0.9689278838449038 0.3325811719823872 1.0 0.5272215593141533 6 Q9NPH0 1 +Retinol metabolism 0.4497571051711519 0.7430552583984568 0.4574482260098926 1.0 0.6343638408666509 4 Q6NUM9 1 +Type i diabetes mellitus 0.4477329564546812 0.5962268339649525 0.5510237016075035 1.0 0.6984727512690564 6 P30511 1 +Ppar signaling pathway 0.3479492258690279 0.4519868864599625 0.651278429513074 1.0 0.7556499727042718 20 O00767,P33121,Q9UKU0,Q15067,O14975,P50416,P23786,O95864 8 +Amyotrophic lateral sclerosis als 0.3994015573160289 0.4035658711297614 0.6865319868129096 1.0 0.7698478800587397 11 Q9BUN8,Q16539,O96008,P20339,P07196 5 +Peroxisome 0.2977292523780034 0.3987695309481851 0.6900630296402337 1.0 0.7698478800587397 36 P40855,P28288,O14734,O43808,Q9UKU0,Q15067,Q9NR77,O75192,Q9BY49,O75381,O00116 11 +Fatty acid metabolism 0.2983368103823632 0.370013072343384 0.7113727502633469 1.0 0.7771810891585871 29 Q9UKU0,P50416,P51648,Q9BWD1 4 +Cell adhesion molecules cams 0.3623054896450219 0.2922339750591134 0.7701077364906888 1.0 0.8296994065762778 14 P30511,P10321,P05556,Q92896 4 +Glycosphingolipid biosynthesis ganglio series 0.3575830953896987 0.2594001648151608 0.7953265025608356 1.0 0.8498926242641519 4 O00400 1 +Viral myocarditis 0.3484505302583428 0.2168003831007723 0.8283639133888838 1.0 0.8717085367638835 14 P30511,P78310,Q14118 3 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.3308467576424011 0.1587237077124283 0.8738865589084435 1.0 0.9127265087765976 15 P50402,P16615 2 +Thyroid cancer 0.3159590043923754 0.0062292724813613 0.9950297918059654 1.0 1.0 10 P28702,Q92734,P27361,P06753,P12270,P28482,Q02750,Q16204,P04637 9 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bc7d3c05905cf466cc8f148b8e88ed6588663409 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABI2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADO", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG5", "ALG6", "ALYREF", "ANAPC1", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "APP", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "AURKA", "B3GALT6", "B4GAT1", "BAIAP2", "BCAS2", "BCKDHA", "BCKDHB", "BET1", "BIRC6", "BLM", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BRCA1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CBR1", "CCDC6", "CCNB1", "CCNB2", "CD47", "CD81", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC40", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHPF2", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COASY", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DARS", "DARS2", "DBI", "DBT", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIS3", "DLAT", "DLD", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "ELOB", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPRS", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAH", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "FUT8", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLM", "GFPT1", "GGA1", "GGA2", "GGCT", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HMBS", "HMGB1", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IKBKG", "ILK", "IMPA1", "IMPDH1", "IMPDH2", "INPP4A", "IQGAP1", "IQGAP2", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KDELR1", "KDSR", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LCLAT1", "LDHA", "LDHB", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPCAT4", "LPGAT1", "LRP1", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYPLA1", "M6PR", "MAN1A2", "MAN2A1", "MAN2B1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPI", "MPST", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVK", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCKAP1", "NCL", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NIT2", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NNT", "NPC1", "NPC2", "NR3C1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NT5C2", "NTHL1", "NUDT12", "NUDT5", "NUDT9", "OAT", "OCLN", "OGDH", "ORC3", "ORC5", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS1", "PDSS2", "PECR", "PEX11A", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PI4KA", "PI4KB", "PIAS1", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNA1", "PLXNB2", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "PPA1", "PPA2", "PPAT", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTDSS1", "PTDSS2", "PTGES2", "PTK2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB11B", "RAB13", "RAB31", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAC3", "RAD21", "RAD23B", "RAD50", "RALA", "RAPGEF2", "RARS", "RARS2", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RCOR1", "RDH11", "RDX", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RNASEH2A", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RSL24D1", "RUFY1", "RUVBL1", "RXRB", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SETD1A", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC33A1", "SLC38A2", "SLIT2", "SLK", "SLTM", "SLU7", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SORT1", "SPCS2", "SPCS3", "SPHK2", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGT1", "SYMPK", "TAB1", "TAF6L", "TAF9B", "TALDO1", "TAOK1", "TAP1", "TAP2", "TARS", "TARS2", "TARSL2", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TOMM40", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRAF2", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSG101", "TSPO", "TSTA3", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TXNRD2", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBR5", "UCK2", "UGDH", "UGP2", "UMPS", "UNC45A", "UQCR10", "UQCR11", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USP39", "USP8", "UST", "VAMP7", "VANGL1", "VAPA", "VARS1", "VARS2", "VASP", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS37B", "VPS45", "VPS4A", "VTI1B", "WARS", "WARS2", "WASF2", "WBP11", "WDR61", "XAB2", "XIAP", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX3", "YES1", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD3", "ACAT2", "ACOT8", "ACOX1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ADA", "AGPS", "ALDH3A2", "ALG1", "ALG11", "ALG5", "ASAH1", "ASNA1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "B3GALT6", "B4GAT1", "BET1", "BNIP1", "CANX", "CCDC6", "CD47", "CDIPT", "CDS2", "CHPF2", "CHST14", "CLN5", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "CPT1A", "CPT2", "CTSA", "CXADR", "CYC1", "CYP51A1", "DAG1", "DERL1", "DHCR24", "DOLPP1", "EBP", "EMD", "FADS2", "FDFT1", "FECH", "FUT8", "GALNT1", "GBA", "GLG1", "GLS", "GM2A", "GOSR1", "GPAA1", "GPAT4", "HACD2", "HCCS", "HLA-C", "HLA-F", "HMOX1", "HMOX2", "HS2ST1", "HSD17B12", 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12.598305121005488 1.746958952072276 0.4128488770716938 1.1001714761259436e-06 0.0338882845095652 0.1545448473936569 0.0407851845956189 4.7912228545186304e-08 +Complex i biogenesis 21 38 3.1986626223941568 0.0013806663909681 9.1747572815534 28.546116504854368 0.5440760559261008 0.4236381582634617 4.289696810672699 3.852285850983641 1.2631239118061712 0.3404380044043241 5.87732008727734e-06 0.0295498589150116 0.002010543955723 5.505172787142076e-05 1.970612151106612e-06 +Mitochondrial biogenesis 10 36 2.834967382446027 0.0045830364644701 10.572815533980584 33.521844660194176 0.7125383902440768 0.3998427377933914 4.798567629623383 2.9315837025395943 1.2191838320541302 0.3355715376706868 0.0015085004362212 0.0078165677457274 0.00132313066272 0.0002056124603596 0.0007767330813302 +Rab geranylgeranylation 10 22 2.7940630707857004 0.0052050325914605 7.703883495145631 20.33009708737864 0.0425571144344789 0.6104117024455028 4.535157640190479 2.923418498732157 0.9174138709438756 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0.0614247268920475 0.2707185745648809 0.000798592209508 +Tp53 regulates metabolic genes 7 38 2.7194987504780093 0.0065380942026525 9.567961165048544 35.47572815533981 0.101655991626129 0.675386172281155 4.509186170565808 3.1224046626849615 0.8223942836099251 0.3288916000544298 0.0360482736448476 0.3339036757647639 0.008613239161306 0.0528572065128901 0.050626354259773 +Class i peroxisomal membrane protein import 10 12 2.714422184120924 0.0066391495952362 4.300970873786408 9.604368932038836 1.1426576411245968 0.2560233101944223 2.515331441636984 1.9424437465598188 1.2133199793435778 0.2911424942178205 0.0001372327362865 0.0875404472016038 0.1677870330809631 0.0762921742488627 0.000200465132953 +Sphingolipid de novo biosynthesis 5 13 2.67141282701749 0.0075532688549837 4.08252427184466 10.614077669902912 1.3205451179619188 0.2079933246203462 1.939118365602947 1.3614298144224892 1.289169434780902 0.261809046515659 0.0016340282226502 0.0084566179175882 0.031373049189738 0.0005910649168726 0.0023211498250519 +Rhog gtpase cycle 14 38 2.6596628527907065 0.0078218905643561 9.8373786407767 35.66504854368932 0.6614029400837433 0.4973720188279035 4.308521802053122 2.993429981792782 0.9950331841901028 0.3588671909523165 0.0003199299915 1.0 0.497470817800254 0.2468458051395524 0.0001400096616651 +Attachment of gpi anchor to upar 3 5 2.625327614759471 0.0086565630507347 1.7281553398058251 4.050970873786408 0.3650490188514708 0.4588417110466823 1.1121061515765476 1.035685612757101 1.021268150080817 0.3062595682607533 0.0028218227860889 1.0 1.0 0.1577810442013011 0.0034377129995212 +Formation of atp by chemiosmotic coupling 4 10 2.5698246380641727 0.0101750006705412 3.5898058252427183 9.805825242718448 0.4783111855246443 0.2899716869602585 2.2195497140568734 0.9063771094889388 1.382334358445268 0.2713732710506487 0.0002662511149375 0.0652597674910206 0.0077184558590264 0.0002778449152815 0.0003671727016274 +Transport of bile salts and organic acids metal ions and amine compounds 3 5 2.5585150625701045 0.0105120266044116 1.8349514563106797 3.995145631067961 1.0286208624357371 0.2748571167414633 1.258733277411433 1.3329199016551914 1.161382969627279 0.2758406238802445 0.1752331998738656 1.0 1.0 1.0 0.2015708610705285 +Ras processing 1 5 2.5241401328633524 0.0115981685174044 1.3519417475728157 4.871359223300971 1.1011688928930974 0.2799307194914149 1.0191949595335985 0.8620674500492106 1.0561018280407846 0.2880746444526379 0.2119278063992609 1.0 0.1677870330809631 0.0762921742488627 0.2348875720984273 +Peptide ligand binding receptors 4 7 2.5223197165370665 0.0116583692948466 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0391533499163334 1.0 1.0 0.062605312422627 0.0465653262864464 +Class a 1 rhodopsin like receptors 4 7 2.5223197165370665 0.0116583692948466 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0670925958920387 1.0 1.0 0.090818300458346 0.0790607116166092 +Mitophagy 6 11 2.476319823978995 0.0132744607108135 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.003884408184972 0.0058373227860703 0.0015052123544451 0.0024379570615939 0.0001024209024739 +Metabolism of fat soluble vitamins 2 5 2.459303836109878 0.0139206749470939 1.6650485436893203 4.580097087378641 0.3536798037155611 0.3331745511018804 1.178052427490116 1.3130753903966457 1.3422038796699125 0.2910915635007025 0.1421030365983898 1.0 1.0 1.0 0.1645088237572309 +Heparan sulfate heparin hs gag metabolism 4 5 2.4156846035183026 0.0157056589314923 2.4320388349514563 4.83252427184466 0.8003221575390526 0.2230961855611341 1.2648123228701085 1.2708877857521428 1.4628061886044337 0.2633127679646707 0.4290564413347806 1.0 1.0 0.544318157098314 0.4647244871500471 +Cytoprotection by hmox1 13 68 2.390799646387654 0.016811724290251 15.264563106796116 64.83495145631068 0.939000341067099 0.4699320360831873 6.884300879212943 3.5957015529431366 1.0482386655891682 0.3835416044430508 0.0004283335989292 0.0157117827609153 0.0006473590416804 0.0051861618207084 0.0008474860620808 +Ire1alpha activates chaperones 4 24 2.3890375170040925 0.0168925772406107 6.050970873786408 24.223300970873787 0.9379365742980283 0.4047880585679882 2.6930013625985207 2.1985522104416564 1.0262193137091864 0.3353529084578252 0.0137123465060884 0.1913705796369965 0.0666692325567911 0.0040251974639471 0.0187017730028202 +Glycosphingolipid metabolism 11 17 2.386422604446231 0.0170131880008177 7.514563106796117 15.521844660194176 0.6340330218232789 0.1371235236408302 2.3948329397108954 1.2175929202976112 2.2116324239586063 0.2290247571497847 0.0032687021232355 1.0 0.2732850813359189 0.0449350347407693 0.0045924061823516 +Integrin cell surface interactions 2 5 2.3760792165611373 0.0174977058445553 1.633495145631068 4.203883495145631 0.3179111363730327 0.4479127776597527 1.2499104501809644 0.9864049002328192 1.1220147725505705 0.3186356661300093 0.504721701549886 1.0 1.0 0.5970702236031354 0.5423832826720252 +Alpha oxidation of phytanate 2 5 2.351765219395116 0.0186845641417905 1.5412621359223302 4.174757281553398 0.539716389724763 0.3958664092063569 1.0195879422891667 0.6780495222916898 1.065510461542054 0.2838037972905372 0.0016684345466174 0.028497516818446 0.0563150378970086 0.0082211090226218 0.0020376306093415 +Organelle biogenesis and maintenance 31 105 2.327012474859788 0.0199646013034213 25.364077669902912 93.59466019417476 0.8635708484684039 0.4952956395971041 8.486338013959335 9.495950625534562 1.0729913690397648 0.3929655478972317 0.0615398468172821 0.0089711696955549 0.0041954983931177 0.0135089797627271 0.0369254089750933 +Asparagine n linked glycosylation 33 129 2.3030125661156213 0.0212781360809837 27.868932038834952 117.21601941747574 0.3655728203854831 0.6710619346266642 9.979459770251138 10.454219925563558 0.9141135459616458 0.3576788429802088 0.0037484629642706 0.1130565151475717 0.2095758685931058 0.0361570709526404 0.0003500852099018 +Ion channel transport 18 30 2.3029350622017057 0.021282497043926 9.031553398058252 27.74271844660194 0.8980727715308076 0.3472480807052641 4.2752930421976005 3.4432740668393595 1.4212023690700646 0.3452897078102002 0.1670209711824638 1.0 1.0 0.8672188024394759 0.0449507103926583 +Rac2 gtpase cycle 15 39 2.27129124078784 0.0231293531337892 8.905339805825243 34.74757281553398 0.8419178475366841 0.4471774138928159 4.131135699306596 3.707034631516275 0.9898490308362274 0.3561406142763811 0.0107515010559666 0.3241278561278478 0.1827953867238 0.1331029981740636 0.0056304221630037 +Wnt ligand biogenesis and trafficking 1 5 2.2503164988356805 0.0244288613366951 1.8179611650485437 5.148058252427185 0.2008610757724536 0.5665597263104812 1.4307197314457356 0.6790349494879275 0.831991658391756 0.3012242847769888 0.0597114340227566 1.0 1.0 0.1981219124770219 0.0675218785318175 +Gpcr ligand binding 6 10 2.225772253161696 0.0260294402544656 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.3466526366094063 1.0 1.0 0.3067990234802971 0.3878167330330442 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 2 5 2.2132824532964204 0.0268781785687994 2.2694174757281553 4.735436893203883 0.3669027527063505 0.3957232167693734 1.21588860409113 0.4465689624800877 1.1543527848059545 0.3128036344848447 0.0043638244151776 1.0 1.0 0.1781979724676324 0.0053031795330487 +Processing of smdt1 10 13 2.192484777412077 0.0283445210806509 4.975728155339806 11.155339805825244 0.3833102568885913 0.3649000478471426 2.609615007852169 1.2287595888742628 1.3301610577177632 0.3259664414506655 0.0049015939150874 1.0 1.0 0.3247468214281712 6.703246650942136e-05 +Transport of vitamins nucleosides and related molecules 7 9 2.191165123834766 0.0284398454181695 3.2985436893203883 7.703883495145631 0.5884630304197642 0.3368828823659784 1.766928610360549 0.9135891377639136 1.2550983698791685 0.3076045725047946 0.0020802410254648 1.0 1.0 0.090818300458346 0.0028145739091465 +Heme degradation 1 5 2.181097001203927 0.0291762426086943 1.2936893203883495 3.888349514563106 1.3644540792548048 0.1853348016647351 0.7198024139502899 0.613093535820443 1.150391861359729 0.234811337893219 0.0369771588694818 0.000467906411108 0.0018609890552042 0.0113265963942617 0.0419919493306108 +Synthesis of very long chain fatty acyl coas 3 9 2.177552554949296 0.0294393650783897 3.0800970873786406 7.662621359223301 0.2970725454313344 0.3790733377388842 1.7392923430670622 0.9085681268331954 1.2502564772465108 0.3141166423632316 0.0061836182508931 1.0 1.0 0.062605312422627 0.0078812527225172 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 7 12 2.131798073556345 0.0330234500890969 4.016990291262136 10.99757281553398 1.1239772251284714 0.2752182956921286 1.9514004604865949 1.181365809872934 1.0815649178051203 0.2865915409883788 0.0001372327362865 0.0036723611473879 0.014058804472369 0.0009779431698101 0.000200465132953 +O linked glycosylation 2 6 2.122147556126453 0.0338253489227131 1.766990291262136 4.330097087378641 0.8603336668848929 0.3169450005244383 1.1529100664253755 1.1773621125091884 1.0771631098821022 0.279831511700265 0.2102427054465729 1.0 1.0 0.2076979954646016 0.2403376761227438 +Transport of inorganic cations anions and amino acids oligopeptides 8 10 2.0892573907505296 0.0366845597420946 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.321504766376753 1.0 1.0 0.2887846572413305 0.3610395035532395 +Cholesterol biosynthesis 10 18 2.0845232579199204 0.0371125969028882 5.878640776699029 16.75 1.3996798653689082 0.2350718901934974 2.503362805703168 1.8986773628384943 1.0886216368414 0.270950573691616 6.472963637240823e-06 1.0 0.2070995190727305 0.0024379570615939 9.47697315695096e-07 +Synthesis of pa 5 10 2.07290897236891 0.0381807518620602 2.9635922330097086 8.558252427184467 0.9129149199765416 0.2964837496518883 1.9473992387004595 1.904008254033093 1.1909456358572703 0.2923824193190221 0.1017973825191659 1.0 1.0 0.4587195489148998 0.1188827437046941 +Glycerophospholipid biosynthesis 14 32 2.059075051506772 0.0394870493907364 9.439320388349516 29.58009708737864 1.1800609247564997 0.3081196451067344 4.809346434845489 4.094857299253986 1.3402414818469337 0.3224557628717913 0.0053486464488572 1.0 1.0 0.6207112599576732 0.0085630435153123 +Endosomal vacuolar pathway 3 5 2.0016810563640703 0.0453190450758207 1.7257281553398058 3.8033980582524274 1.062960779733406 0.2609218265454229 1.0520521803495066 0.6329834633310719 1.086072452066713 0.2584156390729046 0.3711832246405026 1.0 1.0 1.0 0.0817606313480972 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7b62605af6b9b234c036437b64055f2417400085 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 1390, + "title": "Average number of proteins per term", + "value": 20.43525179856115 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9e5c1a85cb5606bd5aacdcbb05067fd6d8d22f74 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c7171d1f996c5a77bacccc38c4d4fb52b958e53c --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,266 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.6759748660001017 4.910957784791632 9.063260068208692e-07 0.0012590005133928 0.0012597931494823 75 O14949,P21912,Q86Y39,O95168,Q8N183,P56385,O96000,Q9GZY4,O14548,Q9UDW1,O43819,Q9Y6M9,P13073,O43676,P22695,Q9P0J0,O95139,P00846,P20674,P03886,Q96I36,P03915,P08574,O75964,O95167,P00403,O75880,P14927,P24539,Q9NPL8,Q8N8Q8,Q7L592,Q8IUX1,P06576,O14957,Q9Y375 36 +Respiratory electron transport 0.6663220127340675 4.753305254215563 2.001178577071272e-06 0.0027777758267471 0.0013908191110652 65 O14949,P21912,Q86Y39,O95168,Q8N183,O96000,Q9GZY4,O14548,Q9UDW1,O43819,Q9Y6M9,P13073,O43676,P22695,Q9P0J0,O95139,P20674,P03886,Q96I36,P03915,P08574,O95167,P00403,O75880,P14927,Q9NPL8,Q8N8Q8,Q7L592,Q8IUX1,O14957,Q9Y375 31 +Protein localization 0.6358452922155342 4.616834360992506 3.89638018027938e-06 0.0054013390295304 0.0018053228168632 83 O75746,P40855,P28288,Q8N4H5,P46379,Q8TB36,O14734,Q15067,O14925,Q9NRP2,P05067,Q99595,Q9Y5J9,Q9NS69,Q9Y584,O43681,Q10713,Q9Y276,Q9Y512,O60830,O43808,P49069,Q5T8D3,Q3ZCQ8,Q9UJS0,Q9Y5L4,P09601,P12236,Q13505,P51648,P21796,P12235,O95169,Q9NR77,Q13190,Q9Y5J7,P08574,Q9NX63,Q15388,Q9Y3D6,O75431,O96008,Q96DA6,Q9BY49,O75381,P50402,O00116,P06576,O43615,Q8NBU5 50 +Mitochondrial protein import 0.748782245834289 4.35428066201729 1.3350457469085695e-05 0.0183861339881469 0.0046392839705076 40 Q8N4H5,O14925,Q9NRP2,Q9Y5J9,Q99595,Q9NS69,Q9Y584,Q10713,Q9Y276,Q9Y512,O60830,Q3ZCQ8,Q9UJS0,Q9Y5L4,P12236,Q13505,P21796,P12235,Q9Y5J7,P08574,Q9NX63,Q15388,O96008,O75431,Q96DA6,P06576,O43615 27 +The citric acid tca cycle and respiratory electron transport 0.5695716995461299 4.280426898893312 1.865351523466785e-05 0.0255953676723548 0.0051856772352379 107 O14949,Q8N183,Q86Y39,P21912,O95168,Q8NCN5,P56385,O96000,Q9GZY4,P35613,Q9UDW1,O43819,O14548,Q9Y6M9,P13073,O43676,P22695,Q9P0J0,P00846,O95139,P21796,Q13423,P20674,P03886,Q96I36,P03915,P08574,O75964,O95167,P00403,O75880,P14927,P24539,Q9NPL8,Q8N8Q8,Q7L592,Q8IUX1,P06576,O14957,Q9Y375 40 +Slc mediated transmembrane transport 0.7175659680591155 3.5519586580078393 0.0003823749336673 0.4123376907575696 0.0097230964574147 25 Q99808,Q96QD8,P08195,Q15758,P11166,P35613,P12236,Q15043,Q8TB61,P12235,P30825,Q6NXT4,P05141,Q9Y6M7,Q70HW3,P55011,Q9UBX3,O00400,Q5EBL8,Q9H936,Q8NEW0 21 +Sphingolipid metabolism 0.6749038385608652 3.4881622087887427 0.0004863529260716 0.4914516656884044 0.0100888965481743 30 Q8NBJ7,P04062,O95470,Q9NZJ7,P27544,Q96G23,A0FGR8,P07602,P17900,Q13510,Q5SGD2,P16278,Q9NRA0,P51648,Q9NZD2,P10619,O15269,O43681 18 +Cristae formation 0.7695818318170558 3.3233225965716677 0.0008895198118794 0.7097413277962665 0.0132949735323919 20 Q5XKP0,Q9BUR5,P24539,O75431,P00846,P56385,Q13505,P06576,Q6UXV4,O75964 10 +Transport of small molecules 0.4496028426601147 3.291061666528772 0.0009981003097481 0.7504390870559254 0.014156728883162 163 P28288,Q4KMQ2,Q8N4V1,Q9NWR8,P09601,P45880,Q15043,P21796,P30519,Q9Y277,P63218,O94905,P27105,Q15904,P08195,Q99623,P56589,Q9UJZ1,Q8TB61,P28072,P12235,Q9C0H2,Q9Y6M7,Q70HW3,Q9Y487,O75027,Q9UBX3,Q9UBV2,O00231,Q5EBL8,P36543,Q8NEW0,Q9Y5K8,Q9H0U3,P40855,Q9GZP9,Q15758,Q96TA2,P11166,P35613,P16615,Q9BPX6,Q99797,O95202,P12236,P20020,P07237,P35670,O75477,Q12797,P10644,Q9Y4W6,Q9HD20,P55011,P54709,Q9BUN8,Q8WWC4,P61289,Q92530,Q8WTV0,O00400,P49721,Q9H936,Q99808,P51790,Q9H300,Q10713,Q9UL46,P05023,P30825,Q6NXT4,P05141,Q9NQ11,Q8IYU8,Q93050,P35232,O15118,P98194 78 +Zinc efflux and compartmentalization by the slc30 family 0.8679520888109892 3.219712682400676 0.0012831913538471 0.8321662436255414 0.0168267545457313 2 Q8NEW0 1 +Complex i biogenesis 0.6046874727949554 3.1986626223941568 0.0013806663909681 0.8534593391730844 0.017409953641573 38 Q8N183,Q86Y39,O95168,O96000,Q9GZY4,Q9NX14,Q9Y6M9,O43676,Q9P0J0,O95139,O43674,P56556,O95169,P03886,P03915,O95167,Q9NPL8,Q9UI09,Q7L592,Q8IUX1,Q9Y375 21 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8908009147742659 3.184957343604347 0.0014477534670895 0.8665242465691214 0.017409953641573 3 P67812 1 +Synthesis secretion and deacylation of ghrelin 0.8908009147742659 3.184957343604347 0.0014477534670895 0.8665242465691214 0.017409953641573 3 P67812 1 +Dermatan sulfate biosynthesis 0.8217937481741284 2.9960184746248935 0.0027352986129114 0.977791373072946 0.0272815648439488 2 Q8NCH0 1 +Acyl chain remodelling of pc 0.8209173239848144 2.991708692645735 0.0027742084783419 0.9789637592750792 0.0273485800347187 2 Q8NF37 1 +Metal ion slc transporters 0.8357685563997646 2.9242995941731627 0.0034523229935674 0.9918279170889396 0.0324238443314781 3 Q8NEW0,Q6NXT4 2 +Zinc transporters 0.8357685563997646 2.9242995941731627 0.0034523229935674 0.9918279170889396 0.0324238443314781 3 Q8NEW0,Q6NXT4 2 +Diseases associated with o glycosylation of proteins 0.7931638913234094 2.8539911732085432 0.0043173730865186 0.9975560522008502 0.0366354938263297 2 Q14118 1 +Acyl chain remodelling of pg 0.821157218001175 2.8536169748948694 0.0043224611420993 0.9975733502549512 0.0366354938263297 3 Q8NF37,Q92604 2 +Mitochondrial biogenesis 0.5668809825652488 2.834967382446027 0.0045830364644701 0.998313438396233 0.0377093618382288 36 Q5XKP0,Q9BUR5,P24539,O75431,P00846,P56385,Q13505,P06576,Q6UXV4,O75964 10 +Hs gag degradation 0.7893660531697339 2.834956006712567 0.0045831996589249 0.9983138226940536 0.0377093618382288 2 P54802 1 +Rab geranylgeranylation 0.6532157883553054 2.7940630707857004 0.0052050325914605 0.9992925828863372 0.0410078319627769 22 P62820,Q9H0U4,P20339,P61019,P61026,Q15907,Q9NP72,P20340,Q969Q5,Q9BZG1 10 +Mitochondrial calcium ion transport 0.7105709363985501 2.793019114770769 0.0052218606168428 0.9993090227313312 0.0410078319627769 18 P35232,Q8WWC4,O95202,Q99623,P45880,Q9H300,Q8IYU8,P21796,Q9Y277,Q10713 10 +Abc transporters in lipid homeostasis 0.8082992402104013 2.79088699820065 0.0052563820181623 0.9993415625966914 0.0410470281193578 3 P40855,P28288 2 +Pre notch processing in golgi 0.8342589885998314 2.781025545985244 0.0054187472946596 0.999475224456394 0.0418447707754271 4 Q15363,P16615,Q9UBV2 3 +Hs gag biosynthesis 0.7773882559158775 2.7746179033943568 0.0055266597264878 0.9995486933953548 0.0422091045044947 2 Q7LGA3 1 +Formyl peptide receptors bind formyl peptides and many other ligands 0.8037383750021534 2.768515518555688 0.0056312303774657 0.9996100656976368 0.0425402729602029 3 P05067 1 +Elastic fibre formation 0.7738825591586337 2.7568699705913073 0.0058357552843193 0.9997070361343188 0.0433780740385234 2 P05556 1 +Molecules associated with elastic fibres 0.7738825591586337 2.7568699705913073 0.0058357552843193 0.9997070361343188 0.0433780740385234 2 P05556 1 +Pink1 prkn mediated mitophagy 0.8512403212031667 2.7495961337729193 0.0059668757158646 0.99975611179778 0.0436071215274311 8 Q8N4H5,Q15388,O96008,Q8IWA4,Q9NS69,P21796 6 +The activation of arylsulfatases 0.7964233085113666 2.732501502552947 0.0062855384773998 0.9998438154354028 0.0445291926590529 3 O43681 1 +Other semaphorin interactions 0.7683318726263526 2.728686943179539 0.0063587037284071 0.99985900961919 0.0446393847600302 2 P05556 1 +Intra golgi traffic 0.7517875378481756 2.7204063560024414 0.0065201736587146 0.999887517932627 0.0447165226612453 15 O95721,Q9H9E3,O95249,Q13190,O60476,Q8TBA6,O00461 7 +Tp53 regulates metabolic genes 0.5458370565337468 2.7194987504780093 0.0065380942026525 0.9998903031617538 0.0447165226612453 38 P13073,Q96I36,P20674,Q8N8Q8,O14548,O43819,P00403 7 +Release of apoptotic factors from the mitochondria 0.7936532841737672 2.7188209735236524 0.0065515056932947 0.9998923424063718 0.0447165226612453 3 Q9NR28 1 +Class i peroxisomal membrane protein import 0.8076047158740629 2.7144221841209237 0.0066391495952362 0.9999047674374218 0.0447165226612453 12 P40855,P28288,Q9Y3D6,O43808,Q8TB36,Q9NR77,Q5T8D3,O75381,P51648,Q8NBU5 10 +Linoleic acid la metabolism 0.7654104586619961 2.713813155510581 0.0066513669398136 0.9999063816685808 0.0447165226612453 2 O95864 1 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.8160395270000265 2.6937573408053246 0.0070651581286367 0.999947538238784 0.0467646180895478 4 P67812 1 +Incretin synthesis secretion and inactivation 0.8160395270000265 2.6937573408053246 0.0070651581286367 0.999947538238784 0.0467646180895478 4 P67812 1 +Sphingolipid de novo biosynthesis 0.780797394076811 2.67141282701749 0.0075532688549837 0.999973514034252 0.0492912850160911 13 O95470,P27544,Q96G23,Q5SGD2,P51648 5 +Rhog gtpase cycle 0.5387125305279026 2.6596628527907065 0.0078218905643561 0.9999818197077894 0.0501033543062442 38 Q86Y07,Q8TAA9,P05556,O95202,P49257,Q86XL3,O15173,Q13190,P42167,Q14739,P50402,Q96JJ3,Q6IAA8,Q9Y2U8 14 +Attachment of gpi anchor to upar 0.8214888224779493 2.625327614759471 0.0086565630507347 0.999994356497886 0.0529844258499662 5 Q9H490,Q96S52,O43292 3 +Intrinsic pathway of fibrin clot formation 0.7478819748758372 2.623976796696565 0.0086909705710735 0.9999946223047158 0.0529844258499662 2 P42785 1 +Formation of fibrin clot clotting cascade 0.7478819748758372 2.623976796696565 0.0086909705710735 0.9999946223047158 0.0529844258499662 2 P42785 1 +Wax and plasmalogen biosynthesis 0.7939708230041771 2.58675276721178 0.0096885080541271 0.9999986731307626 0.0577983956877112 4 Q6IAN0 1 +Formation of atp by chemiosmotic coupling 0.7970418517796133 2.5698246380641727 0.0101750006705412 0.9999993298046284 0.0604412432993688 10 O75964,P00846,P06576,P24539 4 +Transport of bile salts and organic acids metal ions and amine compounds 0.8075286663418146 2.5585150625701045 0.0105120266044116 0.9999995825323788 0.0616528142621611 5 Q8NEW0,P35613,Q6NXT4 3 +Acyl chain remodelling of ps 0.7326906222611794 2.5452855509618995 0.0109188408155116 0.9999997642880946 0.0637697005611814 2 Q643R3 1 +Ras processing 0.8003912802061148 2.5241401328633524 0.0115981685174044 0.9999999092967936 0.0661434013054565 5 O43924 1 +Peptide ligand binding receptors 0.8118181620939384 2.5223197165370665 0.0116583692948466 0.9999999166599576 0.0661434013054565 7 Q9NZJ7,P05067,P42892,P07602 4 +Class a 1 rhodopsin like receptors 0.8118181620939384 2.5223197165370665 0.0116583692948466 0.9999999166599576 0.0661434013054565 7 Q9NZJ7,P05067,P42892,P07602 4 +Urea cycle 0.721881390593053 2.4888162048810862 0.0128169205692452 0.9999999836767384 0.0724208113465481 2 Q9Y619 1 +Mitophagy 0.7700112192233771 2.476319823978995 0.0132744607108135 0.9999999914305472 0.0738060015521231 11 Q8N4H5,Q15388,O96008,Q8IWA4,Q9NS69,P21796 6 +Metabolism of fat soluble vitamins 0.7870115302692594 2.459303836109878 0.0139206749470939 0.9999999965527258 0.0758813261821982 5 Q8TC12,Q6NUM9 2 +Er quality control compartment erqc 0.760222370859077 2.420301898679495 0.015507626339889 0.9999999996325696 0.0815155170969205 4 Q9GZP9,Q9UBV2 2 +Heparan sulfate heparin hs gag metabolism 0.7780701754386019 2.4156846035183026 0.0157056589314923 0.9999999997221992 0.0815155170969205 5 Q96L58,P16278,P54802,Q7LGA3 4 +Cytoprotection by hmox1 0.4292442594110415 2.390799646387654 0.016811724290251 0.9999999999417896 0.0847866132404312 68 P13073,Q96I36,O75880,P30519,P20674,P61289,P49721,P09601,Q8N8Q8,O00231,O14548,O43819,P00403 13 +Ire1alpha activates chaperones 0.5664567185907744 2.3890375170040925 0.0168925772406107 0.9999999999480776 0.0847866132404312 24 P43307,Q9NWM8,O95070,Q9Y5M8 4 +Glycosphingolipid metabolism 0.6562944685942509 2.386422604446231 0.0170131880008177 0.9999999999562184 0.0847866132404312 17 P04062,Q9NZJ7,A0FGR8,P17900,P07602,P16278,Q9NZD2,P10619,Q13510,Q8NBJ7,O43681 11 +Integrin cell surface interactions 0.7699929344065494 2.3760792165611373 0.0174977058445553 0.9999999999779368 0.0855032545657924 5 P35613,Q08722 2 +Alpha oxidation of phytanate 0.7650535824935787 2.351765219395116 0.0186845641417905 0.9999999999958884 0.0892492926360441 5 P51648,O43808 2 +Organelle biogenesis and maintenance 0.4100087323714948 2.3270124748597873 0.0199646013034213 0.99999999999933 0.09374719293461 105 Q92973,O75665,Q9Y366,P56385,Q68CZ6,Q16891,Q9NV70,Q13561,Q9NVH1,Q5XKP0,Q10713,Q9Y512,O75935,P00846,Q13505,O43805,O75947,P41208,Q6UXV4,O95684,Q9BUR5,O94927,Q96CS2,Q15154,O43924,O75964,Q9NX63,P24539,O75431,Q9H6D7,P06576 31 +Mucopolysaccharidoses 0.7158238712771052 2.324518203997444 0.0200977370567279 0.9999999999994452 0.09374719293461 3 P54802 1 +Amino acid transport across the plasma membrane 0.7380882782812118 2.309248931157827 0.0209297717373619 0.9999999999998296 0.0955439743110641 4 P30825,Q15758,P08195 3 +Asparagine n linked glycosylation 0.3810529364538452 2.3030125661156213 0.0212781360809837 0.9999999999998962 0.0957367990001851 129 Q86YN1,Q8N6H7,Q9GZP9,P49257,Q9Y3B3,Q9BT22,Q13561,Q15363,P62820,Q2TAA5,P27824,P24390,O75935,O95249,P46977,P49755,Q96AA3,P56962,Q9BYC5,O15155,O75396,Q13190,P10619,O60476,Q96PC5,Q9Y673,Q9BUN8,Q9H9E3,Q9H0U4,Q9UBV2,Q5JRA6,Q9UKV5,Q9H0U3 33 +Ion channel transport 0.5187333863017077 2.3029350622017057 0.021282497043926 0.9999999999998967 0.0957367990001851 30 Q93050,Q9C0H2,Q4KMQ2,P35670,P98194,Q9Y5K8,P51790,Q12797,Q15904,Q9Y487,P20020,Q9NQ11,Q5EBL8,P16615,P36543,P27105,Q9HD20,P05023 18 +Vitamin c ascorbate metabolism 0.7109877264757438 2.299370135371885 0.0214839302994525 0.9999999999999224 0.0963311713427063 3 P11166,P00387 2 +Glutamate neurotransmitter release cycle 0.7098188194038575 2.2932802254686835 0.0218318769447092 0.9999999999999528 0.0975765561194399 3 Q96QD8,O75915 2 +Synthesis of pg 0.7074368686630013 2.28085650489913 0.0225569394571685 0.9999999999999832 0.09807261520122 3 Q8IV08 1 +Rac2 gtpase cycle 0.4905887093960301 2.27129124078784 0.0231293531337892 0.9999999999999926 0.09807261520122 39 Q86Y07,Q8TAA9,P05556,Q9Y512,P49257,Q86XL3,O15173,O96013,Q13505,P42167,Q14739,P50402,Q9UH62,Q6IAA8,Q9Y2U8 15 +Wnt ligand biogenesis and trafficking 0.7446007526493109 2.2503164988356805 0.0244288613366951 0.9999999999999988 0.1014965939977923 5 Q9Y3A6 1 +Cytochrome p450 arranged by substrate type 0.7010056758120692 2.247219221141796 0.0246260203675532 0.9999999999999992 0.1018755009252946 3 Q16850 1 +Plasma lipoprotein remodeling 0.6754309085597467 2.241545717274299 0.024990747648909 0.9999999999999994 0.102772601278058 2 P07237 1 +Gpcr ligand binding 0.7296332873385709 2.225772253161696 0.0260294402544656 1.0 0.1037763467730177 10 Q9NZJ7,P63218,P07602,P05067,Q9NRV9,P42892 6 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7371963050939907 2.2132824532964204 0.0268781785687994 1.0 0.1058375869989554 5 P12235,P12236 2 +Processing of smdt1 0.692032523792951 2.192484777412077 0.0283445210806509 1.0 0.1103610204540753 13 P35232,Q8WWC4,Q99623,Q96TA2,Q9H300,Q9NWR8,Q8IYU8,Q9BPX6,Q9UJZ1,Q10713 10 +Transport of vitamins nucleosides and related molecules 0.7303344814951378 2.191165123834766 0.0284398454181695 1.0 0.1104228634951276 9 Q99808,P05141,P12236,Q5EBL8,Q8TB61,O00400,P12235 7 +Heme degradation 0.7307877027724494 2.181097001203927 0.0291762426086943 1.0 0.1123406571359698 5 P09601 1 +Synthesis of very long chain fatty acyl coas 0.7276943032070375 2.177552554949296 0.0294393650783897 1.0 0.112419553458686 9 Q53GQ0,Q6Y1H2,Q9UKU0 3 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6966794423977034 2.131798073556345 0.0330234500890969 1.0 0.1220813713400125 12 P49069,P09601,P05067,Q13190,P50402,P51648,O43681 7 +O linked glycosylation of mucins 0.7030156234147855 2.130170792381021 0.0331575154731769 1.0 0.1222518475005727 4 Q10472,O43505 2 +O linked glycosylation 0.7369607603836172 2.122147556126453 0.0338253489227131 1.0 0.1240368060582176 6 Q10472,Q8NAT1 2 +Transport of inorganic cations anions and amino acids oligopeptides 0.7036386423270028 2.0892573907505296 0.0366845597420946 1.0 0.1297494606654237 10 P30825,P08195,Q15758,Q9Y6M7,Q70HW3,Q9H936,P55011,Q9UBX3 8 +Cholesterol biosynthesis 0.5968996715309338 2.0845232579199204 0.0371125969028882 1.0 0.1309302276523215 18 Q15125,Q14534,Q16850,O75845,P37268,Q14739,Q9BWD1,Q15392,Q15800,Q15738 10 +Synthesis of pa 0.700552897766035 2.07290897236891 0.0381807518620602 1.0 0.1343575825019336 10 Q9NUQ2,Q643R3,Q86UL3,Q9NPH0,Q8NF37 5 +Glycerophospholipid biosynthesis 0.4848216787859933 2.059075051506772 0.0394870493907364 1.0 0.137398077222032 32 Q96N66,Q9NUQ2,Q92604,Q643R3,Q8IV08,O95674,Q9NQZ5,Q9UG56,O14735,Q53H12,Q86UL3,Q9NPH0,O75131,Q8NF37 14 +Ptk6 regulates proteins involved in rna processing 0.6606140981702392 2.03282210106527 0.0420704994167127 1.0 0.1437211996909543 3 O75525 1 +Endosomal vacuolar pathway 0.6955014263213416 2.0016810563640703 0.0453190450758207 1.0 0.1517352475013532 5 P04439,P30511,P10321 3 +Miscellaneous transport and binding events 0.6974350631430003 1.9536059223773976 0.0507478397027723 1.0 0.1675522498500083 7 Q8N4V1 1 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.684486301822331 1.951703279516499 0.0509734430269608 1.0 0.1678983076006529 9 P60033,P30511,P10321,P78310 4 +Striated muscle contraction 0.7020496964694668 1.9468460696813248 0.0515531918610121 1.0 0.1685159998568842 6 P09493,P06753,P67936,P08670 4 +Diseases associated with n glycosylation of proteins 0.6957133493360895 1.9447527086116916 0.0518047483934147 1.0 0.1685159998568842 7 Q96AA3,Q9BT22 2 +Reduction of cytosolic ca levels 0.6414610260206767 1.9292697021451972 0.0536973889915306 1.0 0.1719801168161926 3 P16615 1 +Platelet calcium homeostasis 0.6414610260206767 1.9292697021451972 0.0536973889915306 1.0 0.1719801168161926 3 P16615 1 +Beta oxidation of pristanoyl coa 0.6632563577901297 1.9225295352305167 0.0545391608900398 1.0 0.1737203767917241 4 P22307,O14734,O15254 3 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.6632563577901289 1.9225295352305132 0.0545391608900402 1.0 0.1737203767917241 4 P22307,O14734,O14975 3 +Intra golgi and retrograde golgi to er traffic 0.3849988980904368 1.9115658728648783 0.0559319001220639 1.0 0.1762932906341698 95 O15260,Q8N6H7,Q9Y3B3,O95235,Q9P2W9,Q12981,Q9UID3,Q13561,Q15363,P62820,O95721,P24390,O75935,O95249,P49755,Q10472,P20340,Q8TBA6,O00461,O60499,O75396,Q13190,O60476,Q9H9E3,O43752,Q9H0U4 26 +Aflatoxin activation and detoxification 0.6604663977551586 1.9077753951578185 0.0564202521921914 1.0 0.1774302048577967 4 Q9UJ14 1 +Selective autophagy 0.4660856814878384 1.898322109443949 0.0576536631992616 1.0 0.1792809661006124 32 Q8N4H5,Q15388,O96008,P08670,Q8IWA4,Q9NS69,P21796 7 +Phospholipid metabolism 0.418609935848254 1.896536390084181 0.0578891527941958 1.0 0.1796114338927057 49 Q9NTJ5,Q8N9F7,Q96N66,Q9NUQ2,Q92604,Q643R3,Q8IV08,O95674,Q9NQZ5,Q9UG56,O14735,Q53H12,Q86UL3,O75131,Q9NPH0,Q8NF37,Q10713 17 +Peptide hormone metabolism 0.5735201345736212 1.8636804823483883 0.0623665878693409 1.0 0.1839058331186789 17 O60645,Q6NXT4,O75787,P67812,Q9NV70,Q8NEW0,Q15005 7 +Cellular response to chemical stress 0.3822041205309343 1.8259794911002336 0.0678533511537942 1.0 0.1959270199495991 79 P13073,O75880,P20674,O14548,P61289,P49721,O43819,P09601,Q8TED1,Q8N8Q8,O00231,Q96I36,P30519,P00403 14 +Unfolded protein response upr 0.4351141483551065 1.8138683254346568 0.0696980002572671 1.0 0.1989326906726926 41 P43307,Q9NWM8,O95070,Q9Y5M8 4 +Response to elevated platelet cytosolic ca2 0.4467616202354941 1.8050530504028424 0.0710663809107405 1.0 0.1996633391768345 36 Q92520,Q9NTK5,Q9NZJ7,Q8NBM8,O94919,O43852,P05067,P07602,Q9UEU0,Q9Y6I9,P13473,Q6UXV4,Q96JJ7 13 +Autophagy 0.4094961816948216 1.8016571800785357 0.0715993589683008 1.0 0.2002477041568172 49 Q8N4H5,Q15388,O96008,O95140,P08670,Q8IWA4,Q9NS69,P21796,P13473,Q6IAA8 10 +Gaba receptor activation 0.638291739882667 1.7896677579197302 0.0735073385911173 1.0 0.2041678674070719 4 Q9Y639 1 +Diseases of glycosylation 0.5204082734434012 1.78634819503402 0.0740428979795055 1.0 0.204287900318185 21 Q2TAA5,O43505,Q96L58,Q8NCH0,O60762,P16278,Q14118,Q9BT22,P10619,Q96AA3,Q93063 11 +Ion transport by p type atpases 0.6330981791114487 1.7792935768112352 0.0751916434807551 1.0 0.2053466992133001 12 P35670,P20020,Q9NQ11,Q5EBL8,P16615,P98194,Q9HD20,P05023 8 +Sumoylation of intracellular receptors 0.6080194635890075 1.7456077230710934 0.0808791393311862 1.0 0.2137300450006634 3 P04150 1 +Post translational modification synthesis of gpi anchored proteins 0.6503365101095885 1.7377568581811895 0.0822536653686043 1.0 0.2146842515891302 8 Q9Y2B2,Q9H490,Q96S52,O43292 4 +Interleukin 15 signaling 0.5848670756646294 1.73765167770072 0.082272208108332 1.0 0.2146842515891302 2 P40763 1 +Nuclear signaling by erbb4 0.625776370408986 1.7223596638347878 0.0850043857912965 1.0 0.2189668454793255 4 Q92542,P16949 2 +Free fatty acids regulate insulin secretion 0.5964348334307445 1.6811626190926994 0.0927313320984273 1.0 0.2343573665760254 3 P29992,O95573 2 +Miro gtpase cycle 0.6335223768737341 1.677667771145165 0.0934119744745458 1.0 0.2352221821007586 5 Q8IWA4 1 +Transport to the golgi and subsequent modification 0.3652171717622289 1.61433222212972 0.1064553844982669 1.0 0.2560086236203998 85 Q8N6H7,P49257,Q9Y3B3,Q9HCU5,Q13561,Q15363,P62820,P24390,O75935,O95249,P49755,P56962,Q9BYC5,O15155,O75396,Q13190,O60476,Q96PC5,Q9H9E3,Q9H0U4,Q12893,Q5JRA6 22 +Glycosaminoglycan metabolism 0.5492448373065152 1.609368893782113 0.1075357028097827 1.0 0.2581599773844525 16 P54802,Q9Y2C2,O43505,Q96L58,Q7LGA3,Q8NCH0,Q9P2E5,P16278,Q8TB61 9 +N glycan trimming in the er and calnexin calreticulin cycle 0.5442598079421452 1.5771532517398863 0.1147602666261748 1.0 0.2649780242697394 16 Q9BUN8,P27824,Q9GZP9,Q9UBV2 4 +Cargo concentration in the er 0.5407445578920771 1.5543809698662894 0.12009356979841 1.0 0.273169347652923 16 Q96PC5,Q15363,P49257,O75396,Q13190,P49755 6 +Chondroitin sulfate dermatan sulfate metabolism 0.6258015466631742 1.552196909958943 0.120615115251651 1.0 0.2734992009784582 6 Q96L58,Q8NCH0,Q9P2E5 3 +Depolymerisation of the nuclear lamina 0.6047582864274925 1.55065167154673 0.1209851820820024 1.0 0.2738915359836864 10 P50402,P42167 2 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5250459450495317 1.5435858171983703 0.1226887030681167 1.0 0.2768462617933154 17 Q07065,O43852,Q02818,Q5JRA6,O76024 5 +Metabolism of porphyrins 0.5968830907526784 1.5384886131163549 0.1239291905793773 1.0 0.2782901048551446 11 P22830,P30519,P09601 3 +Ikba variant leads to eda id 0.5471808355244037 1.5198245328945337 0.1285550815392802 1.0 0.2846717671074512 2 O15111 1 +Class b 2 secretin family receptors 0.5614381343605614 1.484083474921276 0.1377867766270939 1.0 0.3001747636105502 3 P63218 1 +Metabolism of lipids 0.3367972007270179 1.4825750819274135 0.1381873416099437 1.0 0.3001747636105502 203 O00767,P04062,O14734,P27544,Q92604,Q15067,Q96G23,O75192,O76062,Q53GQ0,P50416,P37268,Q9NZD2,O15269,P23786,O43681,Q10713,Q9NTJ5,P53007,Q8N9F7,O95470,O43808,Q5T8D3,Q9NQZ5,Q6Y1H2,P07602,Q86UL3,Q9NPH0,P51648,O75131,Q13510,O95864,P30536,Q9NZJ7,Q9UKU0,Q96N66,Q16850,Q14534,Q9UG56,O14735,P17900,Q5SGD2,O75845,Q53H12,Q8NBQ5,Q9NRA0,Q14739,Q9P035,Q8NF37,Q6IAN0,P10619,Q15738,Q8NBJ7,Q9NUQ2,Q9H4L5,Q643R3,Q15125,Q8IV08,O95674,Q9H7Z7,Q9UMR5,P50897,Q9BY49,O00116,Q9BWD1,Q15392,Q15165,Q15800 68 +Recruitment of mitotic centrosome proteins and complexes 0.4075422954856351 1.4619843865301814 0.1437454884988713 1.0 0.3078678413149942 37 O75665,O95684,O75935,O94927,Q96RT7,Q96CS2,Q15154,Q9H6D7,O43805,P41208,Q13561 11 +Calnexin calreticulin cycle 0.5940717916539635 1.4610566492008663 0.1439998957206196 1.0 0.3079382385410174 9 P27824,Q9GZP9,Q9UBV2 3 +Copii mediated vesicle transport 0.4083395082894618 1.4165938166352352 0.1566017173995864 1.0 0.3248901301275001 34 P56962,Q15363,P62820,Q9H0U4,P49257,O15155,O75396,P49755,Q13190 9 +Diseases of immune system 0.5473407364114469 1.4037677547441074 0.1603880189017092 1.0 0.3307705434323084 3 O15111,P09429 2 +Copi mediated anterograde transport 0.3457784791508284 1.3960009500937354 0.1627142090441109 1.0 0.3338948908663742 57 Q15363,P62820,Q9H9E3,Q8N6H7,P24390,O75935,O95249,Q9H0U4,Q9Y3B3,O15155,P49755,Q13190,Q13561 13 +Metabolism of steroid hormones 0.5804123034688062 1.3917526943428755 0.163997299447651 1.0 0.3342466953551832 5 Q53GQ0,P30536 2 +Initiation of nuclear envelope ne reformation 0.4936555849709868 1.3897605658776817 0.1646015964037945 1.0 0.3346557642651526 18 Q86Y07,Q86XL3,P50402,P42167,Q9Y2U8 5 +Er to golgi anterograde transport 0.3479676625257353 1.3852472725681833 0.1659768703990165 1.0 0.3349199568016951 81 Q8N6H7,P49257,Q9Y3B3,Q9HCU5,Q13561,Q15363,P62820,P24390,O75935,O95249,P49755,P56962,O15155,O75396,Q13190,Q96PC5,Q9H9E3,Q9H0U4,Q12893,Q5JRA6 20 +Arms mediated activation 0.5235173824130928 1.3809377471343678 0.1672981024831279 1.0 0.3360467665484795 2 P46108 1 +Biological oxidations 0.3878373730201466 1.376265372814359 0.1687394892721865 1.0 0.3379024584478126 42 P16435,Q99735,Q16850,O43169,Q9UJ14,Q9NX62,Q8TB61,P21964,Q9NUJ1 9 +Ubiquinol biosynthesis 0.5423304153370867 1.3751088353541 0.1690977055977041 1.0 0.3379024584478126 3 O75208 1 +Rac3 gtpase cycle 0.3981786583625514 1.3732159465381697 0.1696852236993133 1.0 0.3379118351605238 37 Q86Y07,Q9BSJ8,Q8TAA9,P05556,P49257,O15173,O96013,P42167,Q14739,P50402,Q6IAA8,Q9Y2U8 12 +Peroxisomal lipid metabolism 0.5492779733335771 1.3648992702113691 0.1722847116787231 1.0 0.3394700546605099 13 O14734,O43808,Q15067,Q5T8D3,Q9BY49,O14975,P51648 7 +Translation of sars cov 1 structural proteins 0.5832963626488278 1.349180571896876 0.1772789734937396 1.0 0.3465791464926837 7 Q10472 1 +Rhod gtpase cycle 0.4024133227340331 1.332546523473471 0.1826806643384182 1.0 0.353165679319056 32 Q86Y07,Q8TAA9,P49257,O15173,P42167,P50402,Q9Y2U8 7 +Diseases associated with glycosaminoglycan metabolism 0.5690209502729844 1.329591822101348 0.1836527940298351 1.0 0.3533780423840191 5 Q8NCH0 1 +Interleukin 4 and interleukin 13 signaling 0.542729135536943 1.3254285968725206 0.1850290373962457 1.0 0.3547453268700436 13 P09601,Q07820 2 +Purinergic signaling in leishmaniasis infection 0.5506495283504702 1.3094865267525913 0.1903695986903804 1.0 0.3610010125233684 4 P09601 1 +Inflammasomes 0.5506495283504702 1.3094865267525913 0.1903695986903804 1.0 0.3610010125233684 4 P09601 1 +The nlrp3 inflammasome 0.5506495283504701 1.3094865267525906 0.1903695986903806 1.0 0.3610010125233684 4 P09601 1 +Ra biosynthesis pathway 0.5495562535256738 1.3033828431228434 0.1924440909179092 1.0 0.3637698371715374 4 Q8NBN7 1 +Ecm proteoglycans 0.561621435514031 1.2890835407796548 0.1973690449813987 1.0 0.3695780487623125 5 Q14118,P05067 2 +Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis 0.5048203330411936 1.270248349451769 0.2039961801184358 1.0 0.3780729204861677 2 O75376 1 +Pre notch expression and processing 0.5479487052094093 1.2572428713380452 0.2086657036232551 1.0 0.3831510277890682 11 Q15363,P16615,Q9UBV2 3 +Nuclear envelope ne reassembly 0.3498899159670631 1.254354472236459 0.2097131928630227 1.0 0.3840597339652195 52 Q92973,O75531,P42166,Q7Z3B4,Q9BUF5,Q9Y3E7,O43633,Q8N1F7,P42167,Q9BTX1,Q9BW27,Q86Y07,Q86XL3,Q14739,Q8NFH5,P50402,Q9Y2U8,P02545,O95067 19 +Abc transporter disorders 0.3703046822745036 1.2453178168811792 0.2130149489974651 1.0 0.3871918105493966 44 Q9BUN8,Q9NUN5,Q9GZP9,O75477,P61289,Q9UBV2,O00231,P49721 8 +Synthesis of pc 0.5517025070789199 1.2346403187199066 0.2169643965464538 1.0 0.3891361434833172 5 Q8NF37 1 +Anchoring of the basal body to the plasma membrane 0.3847575745556831 1.2282093995900951 0.219368371065858 1.0 0.391607859970259 36 O75665,O95684,O75935,O94927,Q96CS2,Q15154,Q9H6D7,O43805,P41208,Q13561 10 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.5561956410728754 1.2243833821845322 0.2208076351867085 1.0 0.3934905293711858 8 Q16850,Q14118 2 +Adp signalling through p2y purinoceptor 1 0.5333189323226185 1.212495366421817 0.2253228152190618 1.0 0.3992300357940651 4 P63218,Q16539 2 +Rhoa gtpase cycle 0.3572526142830967 1.2121236626219734 0.2254650471114596 1.0 0.3992300357940651 48 Q96HY6,P28288,Q8TAA9,P51572,P49257,Q5T8D3,O15173,Q96CS3,Q13190,P42167,Q14739,P27105,P30519 13 +Recruitment of numa to mitotic centrosomes 0.3734302643392931 1.2098770045962717 0.2263260922343333 1.0 0.3992300357940651 41 O75665,O95684,O75935,O94927,Q96RT7,Q96CS2,Q15154,Q9H6D7,O43805,P41208,Q13561 11 +Ticam1 rip1 mediated ikk complex recruitment 0.5128579777907509 1.2055050566301335 0.2280083871263696 1.0 0.3992463484540148 3 O15111,Q9Y6K9 2 +Irak1 recruits ikk complex 0.5128579777907509 1.2055050566301335 0.2280083871263696 1.0 0.3992463484540148 3 O15111,Q9Y6K9 2 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4314782246114622 1.1930778131221458 0.2328388998429105 1.0 0.4036109290952085 22 Q9Y673,Q86YN1,Q2TAA5,O60762,P16278,Q9BT22,P10619,Q96AA3 8 +Egfr transactivation by gastrin 0.4875839906514928 1.1676337813736322 0.2429545177477239 1.0 0.4169219502090571 2 P62993 1 +Cytosolic sulfonation of small molecules 0.5239095468247008 1.15965538447294 0.2461891418704738 1.0 0.4202352078306035 4 Q9NX62 1 +Phase ii conjugation of compounds 0.3891873379878786 1.159145449972062 0.2463969024330516 1.0 0.4202352078306035 27 P21964,Q9NX62,Q9NUJ1,Q8TB61 4 +Rab gefs exchange gtp for gdp on rabs 0.3874682237731461 1.1527157918558868 0.2490270574676314 1.0 0.4231633372616231 28 P62820,Q9H0U4,P20339,P61026,Q9NP72,P20340,Q9H2M9,P61020 8 +Heme biosynthesis 0.5487538984126819 1.1397361688278898 0.2543962338324028 1.0 0.4296607108469501 6 Q7KZN9,P22830 2 +Aurka activation by tpx2 0.37310100942606 1.1327834048923158 0.2573052221138676 1.0 0.4340464305076165 37 O75665,O95684,O75935,O94927,Q96CS2,Q15154,Q9H6D7,O43805,P41208,Q13561 10 +Methionine salvage pathway 0.5329354837077096 1.1312704846347892 0.2579412632113222 1.0 0.4345919465015005 5 Q13126,Q9BV57 2 +Myoclonic epilepsy of lafora 0.4799883143441442 1.1222884380641294 0.2617398205084975 1.0 0.4399254540590224 2 P46976 1 +Abc family proteins mediated transport 0.3323195749095491 1.1193913405043827 0.2629732236154976 1.0 0.4414647111419584 54 P40855,P28288,Q9BUN8,Q9GZP9,O75477,P61289,O94905,Q9UBV2,P56589,O00231,O75027,Q9UL46,P49721 13 +Retrograde transport at the trans golgi network 0.4530328683969898 1.052786741629513 0.2924387428276391 1.0 0.4793512411915311 17 Q9H9E3,P20340,O60499,O43752 4 +Runx1 regulates expression of components of tight junctions 0.4653812445223477 1.0349647679731346 0.300685365218456 1.0 0.4882624505299694 2 Q16625 1 +Josephin domain dubs 0.4647969617294767 1.031470227094966 0.3023203630610611 1.0 0.4897730823483391 2 P54727 1 +Nuclear envelope breakdown 0.3469328318822772 0.9811432944804904 0.3265220829615649 1.0 0.5133822652497892 43 Q86Y07,Q8N1F7,O75531,Q8TEM1,P35658,Q9Y2U8,P42167,P50402,Q7Z3B4,Q8NFH5,Q99567,Q9NRG9,Q9BTX1,Q9BW27,P42166,P02545,O95067 17 +Stimuli sensing channels 0.5083900206914166 0.9790420741340148 0.3275591909907094 1.0 0.5133822652497892 9 P51790,Q9C0H2,Q4KMQ2 3 +Insulin processing 0.4957349153129385 0.9783891266063376 0.3278819039649996 1.0 0.5133822652497892 12 O60645,Q8NEW0,Q6NXT4,Q9NV70 4 +Disorders of transmembrane transporters 0.3166567645147227 0.972927341842685 0.3305894148188857 1.0 0.5134968831434751 78 Q9GZP9,P08195,P11166,P35613,Q7Z3B4,Q9NRG9,Q8N1F7,Q8TEM1,Q9UL46,Q9BTX1,Q9BW27,P28072,O75477,O94905,Q8NFH5,P35658,Q9BUN8,Q9NUN5,P61289,Q9UBV2,O00231,O00400,P49721 23 +G protein activation 0.4692353840635833 0.9526261438297609 0.3407795260615072 1.0 0.5225448678631434 3 P63218 1 +Copi dependent golgi to er retrograde traffic 0.3256004005565796 0.9457190787616292 0.3442918887374206 1.0 0.5258964014780382 51 O15260,Q15363,P62820,Q8N6H7,P24390,Q9H0U4,Q9Y3B3,P52732,O75396,O95235,P49755,Q9BVK6,Q9P2W9,Q12981 14 +Rnd1 gtpase cycle 0.4484130370617889 0.9438879577999806 0.3452269063760305 1.0 0.526406048347728 16 Q9BXS4,Q9Y2U8,P51648 3 +Maturation of sars cov 2 spike protein 0.4861194505627997 0.9212893202944706 0.3568993953961368 1.0 0.5386429528779915 12 P27824,P46977,Q9H0U3 3 +Chaperone mediated autophagy 0.4997161802372625 0.8909850834035774 0.3729371726961625 1.0 0.555958390602917 7 P13473 1 +Platelet activation signaling and aggregation 0.3027020868934055 0.8725204230232272 0.3829245315918608 1.0 0.5677755217429163 62 Q92520,Q9NTK5,Q9NZJ7,Q8NBM8,O94919,P63218,O43852,P05067,P07602,P18031,Q9UEU0,Q9Y6I9,P13473,Q6UXV4,Q96JJ7,Q8NCG7 16 +Activation of bad and translocation to mitochondria 0.4879976580796279 0.8636270480068813 0.3877928006744642 1.0 0.5728288979144583 9 P31946,Q04917,P31751,P27348,P63104,Q9Y3B8,P31749,P62258 8 +Regulation of kit signaling 0.4497369959088053 0.8397631999333638 0.4010411705915726 1.0 0.5874048757874457 3 P17252,P62993 2 +Translation of sars cov 2 structural proteins 0.4147305840004032 0.8350153376706294 0.4037090727090144 1.0 0.5900689916567088 18 Q10472,P27824,P46977,Q9H0U3 4 +G beta gamma signalling through pi3kgamma 0.4645790780107119 0.825812195253187 0.4089106350620319 1.0 0.5944447075660647 4 P63218 1 +Regulation of localization of foxo transcription factors 0.4877121123464 0.825181127519652 0.4092687662882905 1.0 0.5944447075660647 7 P31946,P31751,P27348,P63104,Q9Y3B8,P31749 6 +Prevention of phagosomal lysosomal fusion 0.4462302746931628 0.8195328670352358 0.4124824579297965 1.0 0.5966187476820158 3 P51149,P20339 2 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.4674364197507937 0.8105814702632992 0.4176060615141943 1.0 0.6024412827790806 12 O60725,Q9BU89,Q8NBJ7,O43681 4 +Cilium assembly 0.3014472458247283 0.8102296508581591 0.4178081989921105 1.0 0.6024412827790806 69 O75665,Q92973,O95684,O75935,Q10713,Q9Y366,O94927,Q96CS2,Q15154,Q68CZ6,Q9H6D7,O43805,Q9NV70,O43924,P41208,Q13561 16 +Slc transporter disorders 0.3416033080859171 0.7917721561732911 0.4284935403979899 1.0 0.6140268259311402 34 P08195,Q8N1F7,Q8TEM1,P11166,P35613,Q7Z3B4,Q8NFH5,O00400,Q9NRG9,Q9BTX1,Q9BW27,P35658 12 +Pyruvate metabolism 0.423504069537907 0.7778419674200477 0.4366621835450979 1.0 0.6238031193501399 16 Q8NCN5,P21796 2 +Phase i functionalization of compounds 0.4426551611345284 0.7737128852701907 0.4391005984508553 1.0 0.6266425378302761 14 P16435,Q16850,O43169 3 +Muscle contraction 0.3435879127601162 0.7678354932233667 0.4425849249615476 1.0 0.6290317440660033 29 Q9HD47,P60660,Q12797,P67936,P08670,P20020,P06753,P16615,Q9NYL9,P05023,P09493 11 +Synthesis of bile acids and bile salts 0.4703353904081269 0.746459728879989 0.4553897498402475 1.0 0.6412182404931529 8 Q9H4L5,O14734,Q96SU4,Q9BZF3,O14975,P22307 6 +Bile acid and bile salt metabolism 0.4703353904081269 0.746459728879989 0.4553897498402475 1.0 0.6412182404931529 8 Q9H4L5,O14734,Q96SU4,Q9BZF3,O14975,P22307 6 +Defective cftr causes cystic fibrosis 0.3227062047262888 0.7301306270488699 0.4653103419956359 1.0 0.6513673602542817 43 Q9BUN8,Q9GZP9,O75477,P61289,Q9UBV2,O00231,P49721 7 +Transport of connexons to the plasma membrane 0.456140350877193 0.7084542684703996 0.4786632018912196 1.0 0.6617712386941895 5 P04350,Q13885,Q9BUF5,Q9BVA1 4 +Constitutive signaling by overexpressed erbb2 0.443437591347554 0.7079757242316159 0.4789603328742062 1.0 0.6617712386941895 4 P62993,Q96RT1,Q16543 3 +Golgi to er retrograde transport 0.295507321682228 0.7048030503204229 0.4809328100282626 1.0 0.6625338017237711 74 O15260,Q9NSK0,Q8N6H7,Q9Y3B3,O95235,Q9H0B6,Q9NP72,Q9P2W9,Q12981,Q13561,Q15363,P62820,P24390,O75935,P49755,Q9BVK6,Q10472,P20340,Q9H2M9,O75396,Q9H0H5,Q9H0U4,P52732,Q10471,Q07866 25 +Pyroptosis 0.4590989447049917 0.7012144171868884 0.4831692138148726 1.0 0.6642979299729703 9 O43633,O60443 2 +Rnd2 gtpase cycle 0.410132697169805 0.6893320119423624 0.4906143573242536 1.0 0.6707016896553136 16 Q9Y2U8,P51648,Q07065 3 +Visual phototransduction 0.4566960583639654 0.6714715218237423 0.5019201954909245 1.0 0.6819834523288222 8 Q6NUM9 1 +Interactions of vpr with host cellular proteins 0.3257806208593658 0.6432446621392499 0.5200653573323066 1.0 0.7011550404383183 34 Q8N1F7,P05141,O75531,Q8TEM1,P12236,Q7Z3B4,Q8NFH5,Q9NRG9,Q9BTX1,Q9BW27,P35658,P12235 12 +Gap junction assembly 0.456273764258544 0.6412004529099449 0.5213924554181943 1.0 0.702263094022568 6 Q13885,Q9BVA1,Q9BUF5,P36383,P04350 5 +Sialic acid metabolism 0.4302800541209071 0.6354658668956542 0.5251246215074683 1.0 0.7066052506247638 4 P10619 1 +Regulation of plk1 activity at g2 m transition 0.3145017578303959 0.6294200600762856 0.5290740884815779 1.0 0.7098580916886036 42 O75665,O95684,O75935,O94927,Q96CS2,Q15154,Q9H6D7,O43805,P41208,Q13561 10 +Antigen presentation folding assembly and peptide loading of class i mhc 0.3711360762925833 0.5729658248494268 0.5666678337468634 1.0 0.7416838878607721 19 P27824,P51572,Q03519,Q9NZ08,P30511 5 +Apoptotic factor mediated response 0.4247773600342756 0.5272022393108363 0.5980531537839462 1.0 0.7610760806981072 10 Q9NR28 1 +Signaling by retinoic acid 0.4104313746712277 0.5247369353876842 0.5997660772774465 1.0 0.7613468926170325 13 P50416,Q8NBN7 2 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.3912916423144405 0.5091346518870249 0.6106578443484416 1.0 0.7700918740101071 3 P54646,Q16539 2 +Mitotic prophase 0.2728775385071537 0.5089197267642404 0.6108084920498364 1.0 0.7700918740101071 60 O75531,P42166,Q7Z3B4,Q99567,Q01105,Q9NRG9,P62820,Q8N1F7,Q8TEM1,P42167,Q9BTX1,Q9BW27,Q86Y07,Q8NFH5,P35658,Q9H0U4,P61019,P50402,Q9Y2U8,P02545,O95067 21 +Signaling by ptk6 0.3971759907857846 0.4944210996066263 0.6210088157733142 1.0 0.7701163559737305 14 P11802,P23246,O75525,Q14185,P18031,Q96JJ3 6 +Metabolism of folate and pterines 0.4237249698256478 0.4938816858731274 0.6213897393274932 1.0 0.7701163559737305 8 P00374 1 +Small interfering rna sirna biogenesis 0.4033908213972521 0.4904017304800554 0.6238496523931083 1.0 0.7701163559737305 4 Q9UPY3,Q99598,O75569 3 +Cytosolic iron sulfur cluster assembly 0.4265747326945646 0.4866577222055641 0.6265009106059136 1.0 0.7713341592048006 6 O75027 1 +Recycling of eif2 gdp 0.424041093814763 0.4839659843201057 0.6284100100930778 1.0 0.7717795698878288 7 P49770 1 +Fatty acyl coa biosynthesis 0.3635728127005906 0.4803563904588706 0.6309739979102971 1.0 0.7717795698878288 18 O00767,Q9UKU0,Q9UMR5,Q6Y1H2,P50897,Q53GQ0,Q9P035 7 +Unwinding of dna 0.4119574432463868 0.4573019079064123 0.6474540585620094 1.0 0.7811205106971167 10 Q9Y248,P33993,Q9BRT9,Q14566,P49736 5 +Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.413605880363883 0.4303602476165966 0.6669336075771422 1.0 0.7950580742128882 7 Q15067,O14734,O95864 3 +Endosomal sorting complex required for transport escrt 0.4048330404103381 0.4190762048132287 0.6751604403351621 1.0 0.8041756744351973 10 Q9H9H4,Q9BRG1,Q9Y3E7,Q92783,O43633 5 +Sulfur amino acid metabolism 0.3956544614323078 0.3978437582104133 0.6907453595685351 1.0 0.8160790627940869 12 Q13126 1 +Rho gtpase cycle 0.2729191815436901 0.396253986860854 0.6919176680379004 1.0 0.8160790627940869 162 Q96HY6,P28288,Q8N6H7,P05556,P49257,Q15758,P67936,P08670,O96013,P06753,Q9NRG9,Q9UIW2,Q6IAA8,Q9P0I2,Q9Y512,Q8TAA9,O95202,Q5T8D3,Q16543,Q13505,P42167,P51648,P11182,Q9BT78,P30519,Q92783,Q8NHP6,Q86Y07,P51572,Q86XL3,O15173,Q9Y6M7,Q13190,Q96F07,Q14739,Q9NYL9,Q9BXS4,Q9UH62,Q07021,Q07065,Q96JJ3,Q96CS3,P50402,P27105,Q15904,Q14254,Q9BSJ8,Q9Y2U8 48 +Metabolism of steroids 0.2807446339259728 0.3945351794807595 0.6931859596048369 1.0 0.8160790627940869 49 O00767,P04062,O14734,Q9H4L5,Q15125,Q16850,Q14534,O75845,Q53GQ0,P37268,Q8NBQ5,Q14739,Q15800,Q9BWD1,Q15392,Q15738,P30536 17 +Regulation of tp53 activity through association with co factors 0.365283459964936 0.3701467651322464 0.7112731391616669 1.0 0.833691546377344 3 P31749,P31751 2 +Tysnd1 cleaves peroxisomal proteins 0.4010513255646762 0.3592756901675595 0.7193888583972274 1.0 0.8363334567636371 6 Q15067,O00116 2 +Dcc mediated attractive signaling 0.3729903536977488 0.3341262566820155 0.7382842875643787 1.0 0.8502196849332945 4 Q14185,P60953,Q05397 3 +Activation of the ap 1 family of transcription factors 0.3579777907656378 0.3325775328675144 0.7394532050118936 1.0 0.850860889872957 3 Q16539,P27361 2 +Activation of ampk downstream of nmdars 0.391864208369905 0.3304012462922013 0.741096799957017 1.0 0.8513426049093006 8 Q13885,P54646,Q9BVA1,P68371,Q13131,Q9BUF5,P04350 7 +Activated tak1 mediates p38 mapk activation 0.3674364220987961 0.3067850300933979 0.7590070034322489 1.0 0.8640620268393333 4 P61088,Q16539,Q9Y6K9 3 +Translation of replicase and assembly of the replication transcription complex 0.3759084413707007 0.2934927575676305 0.7691455345164477 1.0 0.8720328653979301 5 O43633 1 +Other interleukin signaling 0.3457042665108171 0.2712574971612262 0.786192993663025 1.0 0.8873825903851037 3 P40222,Q12846 2 +P75 ntr receptor mediated signalling 0.3638760396303952 0.2633449112784806 0.7922847467263119 1.0 0.8916482099296978 13 Q9NQC3 1 +Suppression of apoptosis 0.3580824320374117 0.2617648247308082 0.7935027594841988 1.0 0.8916482099296978 4 P23246,P27361,P49840 3 +Cd28 dependent pi3k akt signaling 0.3574978076585752 0.2589966829182816 0.7956377998443145 1.0 0.892604149946406 4 P31749,P42345,P31751 3 +Iron uptake and transport 0.3283562966408395 0.2516069019837427 0.8013449232147027 1.0 0.8953934431418302 18 Q93050,P09601,Q9Y487,P36543,Q15904,P30519 6 +Apobec3g mediated resistance to hiv 1 infection 0.3375219170076007 0.2317852306731965 0.8167048289174832 1.0 0.9067250097406564 3 O75531,P17096 2 +Energy dependent regulation of mtor by lkb1 ampk 0.368929198361614 0.2145461876542745 0.8301211528422663 1.0 0.9208845989231844 7 P54646,P54619,Q13131,P42345,Q9Y2Q5,Q6IAA8 6 +Cardiac conduction 0.353879020514715 0.2111862932844104 0.832741905934026 1.0 0.921859247204586 13 Q9HD47,Q12797,P20020,P16615,P05023 5 +Rab regulation of trafficking 0.2755235774100572 0.2108691687439553 0.832989362941698 1.0 0.921859247204586 38 P62820,P31751,Q9H0U4,P20339,P61026,Q15907,Q9NP72,P20340,Q9H2M9,P61020 10 +Pi metabolism 0.3200916613933376 0.2012146061722333 0.8405307709851231 1.0 0.9282934798908572 18 Q9NTJ5,Q8N9F7 2 +G alpha i signalling events 0.2894943057261347 0.200861556904059 0.8408068281889132 1.0 0.9282934798908572 24 Q9NZJ7,P63218,P07602,P05067,P52292 5 +Disinhibition of snare formation 0.3287551139684407 0.1908945818823847 0.8486081851491716 1.0 0.9354206006005936 3 P17252,Q12846 2 +Regulation of gene expression in beta cells 0.3281706604324991 0.1882234670825165 0.8507014771822217 1.0 0.936984986753794 3 P31749,P31751 2 +P38mapk events 0.3044113350861761 0.1421349292762467 0.88697342867606 1.0 0.9753900837497812 2 Q16539 1 +Regulation of beta cell development 0.3282665887167455 0.1285219021834785 0.8977359665201396 1.0 0.9856658716137394 4 P31749,P31751,Q13573 3 +Rhoc gtpase cycle 0.267721327200601 0.1237852839268517 0.90148528391738 1.0 0.9890012191358784 32 P28288,Q8TAA9,P49257,Q5T8D3,Q13190,P42167,Q14739 7 +Signaling by hippo 0.3461088355763601 0.1161456432245014 0.9075371155043692 1.0 0.9948553553241902 7 P31946,Q07157,Q4VCS5,Q9UDY2,Q13043,P62258 6 +Hedgehog ligand biogenesis 0.2621610444277225 0.1117009125118625 0.9110605557798932 1.0 0.9979307900189532 41 Q9GZP9,P61289,Q9UBV2,O00231,P49721 5 +Insulin receptor recycling 0.3388137071160939 0.0975771043128762 0.9222681058409212 1.0 1.0 10 Q93050,Q9Y487,P21281,P36543,Q15904,Q9Y5K8 6 +Antigen processing cross presentation 0.2431073824197771 0.0974603754509071 0.9223608001908676 1.0 1.0 55 Q9UBG0,Q03519,P61289,P10321,Q12846,O75396,Q03518,P30511,O00231,Q9UL46,P49721 11 +Synthesis of substrates in n glycan biosythesis 0.3111893306497629 0.0904061898033985 0.927964438086109 1.0 1.0 16 O60762,Q9Y673,P10619,Q86YN1 4 +Signalling to ras 0.3045002922267725 0.0864825704899839 0.9310828108907532 1.0 1.0 3 P62993,Q16539 2 +Beta oxidation of butanoyl coa to acetyl coa 0.3033313851548828 0.0818094019825452 0.9347982794377384 1.0 1.0 3 P40939,Q16836 2 +2 ltr circle formation 0.3366481427317848 0.0768484556341325 0.9387441026603704 1.0 1.0 6 O75531,P13010,Q13426,P17096,O75475 5 +Neutrophil degranulation 0.2590206016343584 0.0757845890175642 0.9395904770446756 1.0 1.0 178 O15260,Q4KMQ2,O75787,Q92542,P14174,Q6IAA8,O43681,O95721,Q8WVQ1,P07602,P11279,O75131,P00387,P30519,P20340,Q13510,Q8N2G8,Q9NZJ7,Q08722,O00560,Q5T9A4,Q9NQX7,P17900,O00264,P13473,P61026,Q969Q5,Q8NF37,Q93050,Q9H7Z7,P10321,Q07065,Q96CS3,O00231,P61225,Q9H0U3 36 +Late endosomal microautophagy 0.3322056575637429 0.0698581091169175 0.9443065957131358 1.0 1.0 10 O60664,Q9H9H4,P08670,Q9Y3E7,O43633 5 +Rnd3 gtpase cycle 0.2969359850125183 0.0504483716848426 0.9597650904021426 1.0 1.0 17 Q9Y2U8,Q07065 2 +Regulation of pyruvate dehydrogenase pdh complex 0.3279011787294982 0.0490828471363983 0.960853272932578 1.0 1.0 9 P09622,Q8NCN5,Q15118 3 +Lipophagy 0.3072201110786341 0.0459278910565452 0.9633677237795232 1.0 1.0 4 P54646,O60664,P54619 3 +Phosphorylation of the apc c 0.3259150805270727 0.0444342976119793 0.964558223096446 1.0 1.0 10 Q13042,Q9UJX3,Q9UJX4,P14635,P06493,Q9UJX2,Q9H1A4,P30260,Q96DE5 9 +Telomere c strand synthesis initiation 0.3051739257526983 0.0384799327027145 0.9693050310161092 1.0 1.0 4 Q9NYB0,P49643,P49642 3 +Dna damage recognition in gg ner 0.2892948615890294 0.012616819448351 0.989933501627568 1.0 1.0 17 Q9BT78,P41208,Q99627 3 +Signaling by notch1 pest domain mutants in cancer 0.3183148039789345 0.0109847992702912 0.9912355745201612 1.0 1.0 7 P63208,Q92769,Q13573,O75376,Q13616,Q92542 6 +Ion homeostasis 0.315088066276459 0.0057080482081016 0.9954456611938876 1.0 1.0 11 P54709,Q12797,P20020,P16615,P05023 5 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cc2ad3d8996dca6ee4060a31cfb2b68373cf7b00 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr regulates axonogenesis", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of fzd by ubiquitination", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABI2", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG5", "ALG6", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APEH", "APEX1", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3B", "ATG13", "ATG3", "ATG4B", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCKDHA", "BCKDHB", "BCKDK", "BCS1L", "BET1", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRCA1", "BRD1", "BRD2", "BRD4", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2orf49", "CAB39", "CABLES1", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2G", "CAMLG", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCDC59", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CD81", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CENPF", "CENPH", "CENPI", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMBL", "CMC2", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT11", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COA1", "COASY", "COG4", "COG7", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ9", "COTL1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRCP", "CRK", "CRKL", "CRMP1", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM91A1", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNTB", "FOXK2", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FUT8", "FXR1", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GINS2", "GINS3", "GINS4", "GJC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GM2A", "GMDS", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GYG1", "GYS1", "H1F0", "H2AFX", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKG", "ILF2", "ILK", "IMMT", "IMPA1", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS4", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPCAT4", "LPGAT1", "LRP1", "LRPPRC", "LRRC1", "LRRC8A", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MAGED2", "MAGT1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED17", "MED23", "MED24", "MED25", "MED4", "METAP2", "METTL3", "MFAP1", "MFN1", "MFN2", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS2", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "MYO18A", "MYO1C", "MYO6", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEK9", "NELFB", "NELFCD", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIT2", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NT5C2", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCLN", "OFD1", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACS1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAXIP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD11", "PEBP1", "PECR", "PELP1", "PES1", "PEX11A", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLXNA1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "POFUT1", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPFIBP1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAI", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX17", "STX18", "STX4", "STX5", "STX6", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUFU", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SYMPK", "SYNE1", "SYNE2", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAOK1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM126B", "TMEM59", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMT61A", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TSTA3", "TTC26", "TTC37", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TXNRD2", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCR11", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UST", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WARS2", "WASF2", "WBP11", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WNK1", "WTAP", "XAB2", "XIAP", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCRB1", "ZFYVE16", "ZNF638", "ZW10", "ZWILCH"], "leading_proteins": ["AAAS", "ABCB7", "ABCD3", "ABHD10", "ACAT2", "ACBD5", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSL3", "ACSL6", "ADI1", "AFG3L2", "AGK", "AGPAT5", "AGPS", "AKT1", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ALG5", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKLE2", "ANO6", "APOO", "APOOL", "APP", "ARFGAP2", "ARL6IP5", "ARMCX3", "ASAH1", "ASNA1", "ASPH", "ATAD1", "ATAD3B", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP7B", "B3GALT6", "B4GAT1", "BAG6", "BANF1", "BCAP31", "BCS1L", "BET1", "BNIP1", "BSG", "C19orf70", "C1QBP", "CALU", "CAMLG", "CANT1", "CANX", "CCNB1", "CCNB2", "CD47", "CD81", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDIPT", "CDK1", "CDK4", "CDS2", "CERS1", "CERS2", "CETN2", "CHCHD3", "CHMP2A", "CHMP3", "CHPF2", "CHST14", "CHUK", "CKAP4", "CLCN3", "CMC2", "COA1", "COG4", "COMT", "COPS4", "COPS8", "COQ9", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2L", "CPNE3", "CPT1A", "CPT2", "CRK", "CTSA", "CUL1", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAG1", "DAGLB", "DBT", "DCTN2", "DCTN3", "DDRGK1", "DERL1", "DERL2", "DHCR24", "DHFR", "DHRS7B", "DIABLO", "DICER1", "DLD", "DNAJC11", "DNAJC19", "DOCK1", "DOHH", "DOLPP1", "DPM1", "EBP", "ECE1", "EIF2B2", "ELMO2", "EMC3", "EMD", "ENDOD1", "ERAP1", "ERBIN", "ERLIN1", "ERLIN2", "ESYT1", "ESYT2", "EXOC1", "EXOC3", "EXT2", "FADS2", "FAF2", "FAM3C", "FDFT1", "FECH", "FGFR1OP", "FIS1", "FKBP14", "FLOT2", "FUT8", "GALNT1", "GALNT2", "GBA", "GDAP1", "GDPD1", "GGT7", "GHDC", "GINS2", "GINS4", "GJC1", "GLB1", "GLTP", "GM2A", "GNA11", "GNG5", "GOLGA5", "GOLIM4", "GOSR1", "GPAA1", "GPAT4", "GPX8", "GRB2", "GSDME", "GSK3A", "GYG1", "HACD2", "HACD3", "HADH", "HADHA", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HDAC2", "HEBP1", "HLA-A", "HLA-C", "HLA-F", "HMGA1", "HMGB1", "HMOX1", "HMOX2", "HS2ST1", "HSD17B11", "HSD17B12", "ICMT", "IFT52", "IKBKG", "IMMT", "IMPAD1", "ITGB1", "ITM2C", "KDELR1", "KHDRBS3", "KIF11", "KIF20A", "KLC1", "KLC2", "KLC4", "KPNA2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LBR", "LEMD3", "LETM1", "LMAN1", "LMBRD1", "LMNA", "LPCAT1", "LPCAT4", "LPGAT1", "MAGT1", "MAIP1", "MAN1A2", "MAPK14", "MAPK3", "MBOAT7", "MCL1", "MCM2", "MCM6", "MCM7", "MCUB", "MFN1", "MFN2", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MIPEP", "MMGT1", "MOSPD2", "MRC2", "MSMO1", "MTAP", "MTCH1", "MTOR", "MTX1", "MTX2", "MYL6", "NAGLU", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA3", "NDUFA6", "NDUFAF1", "NDUFAF2", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NNT", "NPC1", "NPTN", "NR3C1", "NSDHL", "NUCB1", "NUP210", "NUP214", "NUP35", "NUP54", "NUP85", "NUP88", "NUP93", "OCLN", "OFD1", "OLA1", "OSBPL3", "OSBPL6", "OSBPL9", "P4HB", "PAK4", "PARL", "PCM1", "PCYOX1L", "PDE6D", "PDK1", "PDPR", "PDZD11", "PECR", "PEX11A", "PEX14", "PEX19", "PEX3", "PGRMC1", "PGRMC2", "PHB", "PHB2", "PIGL", "PIGS", "PIGU", "PISD", "PLD3", "PLIN3", "PLXNA1", "PMPCA", "POMGNT2", "PON2", "POR", "PPM1L", "PPT1", "PPT2", "PRCP", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCA", "PRKRA", "PSAP", "PSIP1", "PSMB2", "PSMB6", "PSMD11", "PSME2", "PSME3", "PSMF1", "PTGES2", "PTK2", "PTPN1", "PXMP2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB34", "RAB3GAP2", "RAB5A", "RAB5B", "RAB6A", "RAB7A", "RACGAP1", "RAD23B", "RANGRF", "RAP2B", "RDH11", "RDH13", "RETSAT", "REXO2", "RFT1", "RTN4", "SACM1L", "SAMM50", "SC5D", "SCARB1", "SCD", "SCO1", "SCO2", "SCP2", "SDCBP", "SDHB", "SEC11A", "SEC22B", "SEL1L", "SET", "SFPQ", "SGPL1", "SKP1", "SLC12A2", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A22", "SLC25A26", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SNAP29", "SNW1", "SPCS2", "SPHK2", "SPTLC1", "SQLE", "SRPRB", "SSNA1", "SSR1", "STAM", "STARD7", "STAT3", "STK4", "STMN1", "STOM", "STOML2", "STT3A", "STX10", "STX17", "STX18", "STX4", "STX5", "STX6", "SUMF2", "SURF4", "TAP1", "TAP2", "TERF2IP", "TEX264", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM126B", "TMEM59", "TMOD3", "TMPO", "TMX3", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TPM1", "TPM3", "TPM4", "TSNAX", "TSPO", "TTYH3", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP6", "TXLNA", "UBE2N", "UQCR10", "UQCR11", "UQCRB", "UQCRC2", "UQCRQ", "UST", "VANGL1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS25", "VPS37B", "VPS51", "VRK2", "VTI1B", "WFS1", "XRCC4", "XRCC5", "YIF1A", "YME1L1", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ"]} \ No newline at end of file diff --git a/msigdb_wp/advanced/idx2term.json b/msigdb_wp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a41bc1bf211c8f3f8c8700dcee58fa4e6f3bf2c5 --- /dev/null +++ b/msigdb_wp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Electron transport chain oxphos system in mitochondria", "1": "Nonalcoholic fatty liver disease", "2": "Mitochondrial complex i assembly model oxphos system", "3": "Mitochondrial complex iv assembly", "4": "Oxidative phosphorylation", "5": "Mitochondrial complex iii assembly", "6": "Cholesterol 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4.347454285118301e-12 1.0420969741236244e-16 +Nonalcoholic fatty liver disease 22 63 3.8822298500973256 0.0001035029738376 14.446601941747574 49.78883495145631 0.8140299356769594 0.4039994838731682 5.918094936421778 5.382150615191258 1.5259550974793896 0.3817978315095583 3.58693299061036e-06 0.0003284154666529 3.241712931951668e-07 1.084202640355499e-05 6.200044222602462e-07 +Mitochondrial complex i assembly model oxphos system 19 37 3.471553597906526 0.0005174560226643 8.808252427184467 26.563106796116504 0.7827212026364002 0.3851038550171766 4.050605834390814 3.9632288075289823 1.2210776523685654 0.3331428769936953 7.742945808380523e-08 0.2295798469686227 0.0149914480702132 4.204252026569053e-05 2.3830261990575243e-08 +Mitochondrial complex iv assembly 9 14 3.2984035233641644 0.00097236287827 4.645631067961165 11.985436893203884 1.036764412652062 0.2236438909453165 2.399566170297607 1.9080263664188637 1.5325215618909758 0.2795558816325345 1.626855989834023e-06 0.0115082778780227 7.311156439874239e-07 1.114883762184938e-06 3.03436196363312e-06 +Oxidative phosphorylation 18 36 3.2135072038723047 0.0013112450865184 10.094660194174756 30.308252427184467 0.4493106572238387 0.4094278581483465 4.631390429635194 3.3340884045985604 1.35936739882113 0.3321380007425058 3.603774716135804e-07 0.0257535715284909 0.0001345504873834 3.680912371066755e-06 1.0842199331688697e-07 +Oxidation by cytochrome p450 4 6 2.707460280534244 0.0067800183312798 2.3179611650485437 5.422330097087379 1.262256455948566 0.1900711291682963 1.161003800051733 0.6764315332620536 1.214909583878196 0.2447393771863318 0.0001777475819892 0.0017062060788896 0.0002296483500821 0.003355333516566 0.0002457979454447 +Mitochondrial complex iii assembly 8 11 2.649521839564581 0.0080605762328107 3.3106796116504853 9.259708737864075 1.0287385637679851 0.2644162586394033 1.7668969355473032 1.3138647920792297 1.192785152283574 0.2813694304742245 0.0003845948196129 0.0697581245313758 0.0088504827764808 0.000371706641515 2.790949798364146e-06 +Proteoglycan biosynthesis 4 6 2.637752040108907 0.0083457581381529 1.966019417475728 4.298543689320389 1.0185999272660573 0.2724845511957944 1.255593573941796 1.5981475367005755 1.1753810774067486 0.2740057085210428 0.0003845948196129 1.0 0.1349531130589082 0.0051503840765812 0.0005289198821125 +Sphingolipid metabolism integrated pathway 4 8 2.614849389304011 0.0089266808654635 4.058252427184466 8.101941747572816 1.3056837288293504 0.1731905617886817 2.1182299017960826 1.603786816240382 1.4154175704443392 0.233855234687812 0.0012812224659895 0.0875404472016038 0.1677870330809631 0.0102137155300364 0.0017429018144962 +Sphingolipid metabolism overview 4 8 2.614849389304011 0.0089266808654635 4.0 7.951456310679611 1.305604070038762 0.1692072490812911 2.0060587839493125 1.5113078035984122 1.4254327231792938 0.2283290755268721 0.0007350148232219 0.0786913117950012 0.1515272625734178 0.0074273483269255 0.0010053263520343 +Cholesterol metabolism with bloch and kandutschrussell pathways 12 25 2.4876528058599043 0.0128589199407247 7.092233009708738 23.070388349514563 1.3045876527781233 0.2885598195159411 3.1892169450204397 2.132138915277104 1.1515799969949023 0.3088028425519339 0.000202036679224 1.0 0.3009165941166509 0.0118572988629309 5.121649611699266e-05 +Cholesterol biosynthesis with skeletal dysplasias 5 7 2.47122841913925 0.0134649782093423 2.703883495145631 6.024271844660194 1.6250539245333766 0.1427602110791373 1.3052115351448448 0.7101163612316155 0.9675759117714408 0.205892393525391 0.0001305835606601 1.0 0.0653907127050202 0.0113265963942617 5.11944457815466e-06 +Zinc homeostasis 4 5 2.3453002385096293 0.0190117632425239 0.6973293768545994 1.9525222551928785 1.2400878900463903 0.2228715481064509 0.810040106782955 1.041056807388981 1.502966485729551 0.2675839368124507 0.2288716478191821 1.0 1.0 1.0 0.2531867173469597 +Overlap between signal transduction pathways contributing to lmna laminopathies 5 14 2.2423197516049145 0.0249407140988096 4.927184466019417 14.766990291262136 1.2077866030529698 0.2877996039599693 1.943257907759383 1.4611731122572065 0.935661776029738 0.2919054664837305 0.0152352559216179 1.0 0.3530974878629287 0.0044406378118471 0.020723717832043 +Cellular proteostasis 1 5 2.1975922518651982 0.0279781758719959 2.0679611650485437 4.271844660194175 0.5264789683544518 0.4206045803169084 1.1385746149601492 0.8469726185929765 1.0177721083239633 0.3027668715946303 1.0 1.0 1.0 1.0 1.0 +Sphingolipid pathway 5 10 2.126429921979128 0.0334674785214887 4.274271844660194 9.393203883495143 1.2258474538683668 0.1888473674707098 2.02173101931241 1.3620203536909472 1.3696572221543342 0.2416569853225122 0.015895687074825 0.1006582454154426 0.191600110602388 0.0983610682747182 0.0200033311952484 +Familial partial lipodystrophy fpld 6 7 2.1192167491569074 0.0340721534369881 2.7354368932038833 7.351941747572815 1.0487704575374006 0.2220749325398317 1.64741826657551 0.7567951823729889 1.2080189526980365 0.2461617416466816 0.245901021714267 1.0 0.1837383274168749 0.090818300458346 0.2715157705871365 +Omega3 omega6 fatty acid synthesis 3 6 2.0820250494267003 0.0373401817373213 2.186893203883495 5.679611650485437 0.6147861513210825 0.4189854893383595 1.4636445594342842 0.6147632306564689 0.961935437880314 0.3073297118149702 1.0 1.0 1.0 1.0 1.0 +Ferroptosis 6 24 2.043360748519824 0.0410167400450873 6.247572815533981 23.589805825242717 0.9586016481897424 0.3324276931898122 2.8577723913591164 2.1450310521583007 1.2134257594151 0.3161491716459103 0.0077099574653339 0.0248381956323572 0.0014189260290535 0.0075944976014186 0.0110551101007063 +Statin inhibition of cholesterol production 1 5 2.012981794223778 0.0441165446678473 2.0315533980582523 5.029126213592233 1.044092701346018 0.2144191485801186 1.2890406286437517 1.2084356467042294 1.2621579412510306 0.2395890160394713 0.1302665862694917 1.0 1.0 0.290751966651369 0.1457988469723397 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b2c8560de1c40ea3418f7932f2909f65379f15e8 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 604, + "title": "Average number of proteins per term", + "value": 11.528145695364238 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4069bae1f6a222e0166c95a384f061b806a0486a --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9c8940c963967c9159efd46dcf359254a01bed59 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,104 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Electron transport chain oxphos system in mitochondria 0.6874401718647613 4.907337075444846 9.232128960658822e-07 0.0005574654050153 0.0005576205892243 59 O14949,P21912,O95168,P56385,O96000,O14548,Q9UDW1,Q9Y6M9,P13073,O43676,P22695,O95139,P00846,P12236,P14406,Q7KZN9,P12235,P20674,P05141,P03886,P03915,O75964,O95167,P00403,O75880,P24539,P06576,O14957 28 +Nonalcoholic fatty liver disease 0.5723490889218936 3.8822298500973256 0.0001035029738376 0.0606048156501934 0.007814474524743 63 O14949,P21912,Q86Y39,O95168,O96000,Q9NX14,O14548,Q9UDW1,Q9Y6M9,P13073,O43676,P22695,Q9P0J0,O95139,P14406,Q96GC9,P20674,P08574,O95167,P00403,P14927,O14957 22 +Mitochondrial complex i assembly model oxphos system 0.644125073277133 3.471553597906526 0.0005174560226643 0.2684753266857115 0.0156271718844648 37 Q8N183,Q9NW81,O95168,O96000,Q9GZY4,Q9NX14,Q9Y6M9,O43676,Q9BUB7,Q96CU9,Q9P0J0,O95139,P03886,P03915,O95167,Q9NPL8,Q7L592,Q8IUX1,Q9Y375 19 +Mitochondrial complex iv assembly 0.8828162063074942 3.2984035233641644 0.00097236287827 0.4443367877120089 0.0206341122812223 14 P13073,Q9Y2R0,P20674,Q9Y241,Q8N8Q8,P14406,Q96I36,O43819,P00403 9 +Oxidative phosphorylation 0.6146787224662299 3.2135072038723047 0.0013112450865184 0.5472937119088133 0.0225721361346791 36 O95169,Q86Y39,O95168,P24539,O95139,P00846,P03915,P56385,O96000,O75787,P06576,O75947,P03886,Q15904,O43674,Q9Y6M9,O75964,O95167 18 +Inclusion body myositis 0.8463336254747316 3.115739257624158 0.0018348443349618 0.670198378796616 0.0270303897150475 2 Q92542 1 +Urea cycle and related diseases 0.8220858895705518 2.9974545416519622 0.0027224445761322 0.8072958041006546 0.0357468809561712 2 Q9UJS0 1 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.773006134969326 2.75242672302037 0.005915538338828 0.9722243373227752 0.0537920417422353 2 P08195 1 +Oxidation by cytochrome p450 0.8589404286787836 2.7074602805342436 0.0067800183312798 0.9835770687526114 0.0570739254463926 6 P16435,Q6UW02,Q16850,O43169 4 +Metabolism of spingolipids in er and golgi apparatus 0.8186482568673081 2.706311753609021 0.0068035142916229 0.9838100609976136 0.0570739254463926 4 Q10472,O95470 2 +Mitochondrial complex iii assembly 0.8040849529115095 2.649521839564581 0.0080605762328107 0.9924659003328364 0.0622325668573382 11 O14949,P14927,P22695,Q9BRT2,Q6DKK2,O14957,Q9UDW1,P08574 8 +Proteoglycan biosynthesis 0.8439487813987263 2.637752040108907 0.0083457581381529 0.9936670587242384 0.0622325668573382 6 Q8NCH0,Q9NX62,Q8WVQ1,Q8TB61 4 +Sphingolipid metabolism integrated pathway 0.8230613748796611 2.614849389304011 0.0089266808654635 0.9955547736244514 0.0634319440322351 8 O15269,O95470,Q96G23,P27544 4 +Sphingolipid metabolism overview 0.8230613748796611 2.614849389304011 0.0089266808654635 0.9955547736244514 0.0634319440322351 8 O15269,O95470,Q96G23,P27544 4 +Irinotecan pathway 0.7294770669003885 2.5285390635140623 0.0114538339685701 0.9990490416993004 0.069483738959424 2 O15118 1 +Nuclear receptors in lipid metabolism and toxicity 0.7280163599182086 2.520915380710316 0.0117049996303473 0.9991843470733892 0.069956949525227 2 P28288 1 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.5657007595496767 2.4876528058599043 0.0128589199407247 0.9995972345398084 0.0739694061352166 25 O00767,Q15125,Q16850,Q14534,O75845,P37268,Q14739,Q15800,Q9BWD1,Q15392,Q15738,O95864 12 +Cholesterol biosynthesis with skeletal dysplasias 0.8012206868750457 2.47122841913925 0.0134649782093423 0.9997220578805056 0.0767249701739884 7 Q15125,Q16850,O75845,Q14739,Q15392 5 +Pkcgamma calcium signaling pathway in ataxia 0.7131171486999706 2.4427358858919024 0.0145764003691069 0.9998593087297056 0.0800376892994597 2 P29992 1 +Zinc homeostasis 0.7637426900584849 2.3453002385096293 0.0190117632425239 0.9999907756661238 0.0919345006920309 5 Q8NEW0,Q15043,Q6NXT4,Q8N1S5 4 +Transcription factor regulation in adipogenesis 0.6920829681565881 2.3310566468652403 0.0197503728934065 0.9999941472738844 0.0946763906953773 2 Q16822 1 +Acquired partial lipodystrophy barraquersimons syndrome 0.7293189125986734 2.264832069531174 0.0235229866504296 0.9999994300159976 0.1084571292890037 4 O60725,Q03252,P02545 3 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.6845699717056878 2.2423197516049145 0.0249407140988096 0.9999997630058272 0.1141226614824318 14 P55209,P50402,P42167,O60725,O75844 5 +Cellular proteostasis 0.7340690984110319 2.1975922518651982 0.0279781758719959 0.9999999639990772 0.1232455041949964 5 Q99471 1 +Sphingolipid pathway 0.7106763662371244 2.126429921979128 0.0334674785214887 0.9999999988230748 0.1384545001847892 10 O95470,P04062,Q96G23,O15269,Q13510 5 +Familial partial lipodystrophy fpld 0.7299590403744711 2.1192167491569074 0.0340721534369881 0.9999999991935256 0.1399971474553797 7 P31751,Q03252,O75531,O60725,O75844,P02545 6 +Familial hyperlipidemia type 3 0.6485539000876474 2.0950069406288807 0.0361703755003763 0.999999999783148 0.1456460453481822 2 Q8WTV0 1 +Omega3 omega6 fatty acid synthesis 0.7289087358064231 2.0820250494267003 0.0373401817373213 0.9999999998958646 0.1483780905877769 6 Q15067,P33121,O95864 3 +Ferroptosis 0.5202471119544865 2.043360748519824 0.0410167400450873 0.9999999999896756 0.1541801043661261 24 Q9NZ45,Q9UKU0,P09601,P45880,P37268,Q9Y277 6 +Statin inhibition of cholesterol production 0.6977025872616263 2.012981794223778 0.0441165446678473 0.9999999999985392 0.1550485419389372 5 Q14534 1 +Nanoparticle triggered autophagic cell death 0.6769105385268118 1.994391202697812 0.0461093191675288 0.999999999999586 0.159143021583928 4 Q9Y371 1 +Ovarian infertility 0.6519579193454161 1.9861715384977143 0.0470142799894515 0.9999999999997664 0.159531601761959 3 P11802,O75376 2 +Mitochondrial immune response to sarscov2 0.6643197648176613 1.878682440252369 0.0602878668877391 1.0 0.188672909845567 10 Q9Y375,Q99623,Q9Y6M9,P35232 4 +Sphingolipid metabolism in senescence 0.6565557292805635 1.872579987411352 0.0611264069878065 1.0 0.1892074944110907 11 P04062,Q96G23,Q13510,P16278,O15269 5 +Influence of laminopathies on wnt signaling 0.662172011707435 1.867039677776429 0.0618960471653984 1.0 0.1892074944110907 10 O75844,P50402 2 +Regulation of apoptosis by parathyroid hormonerelated protein 0.6726694533948474 1.8561711519652215 0.0634291665819177 1.0 0.1925186764596901 8 Q9BXK5 1 +Striated muscle contraction pathway 0.6384883237967947 1.6189244336774626 0.1054635229834852 1.0 0.2710636931150004 6 P09493,P67936,P08670 3 +Copper homeostasis 0.6201891666048645 1.605140169184805 0.1084629609317004 1.0 0.2740138343004322 9 O75880,O43819,P35670 3 +Glycosylation and related congenital defects 0.6130819263597617 1.5971123528054425 0.1102406651241805 1.0 0.2740138343004322 10 O60762,Q2TAA5,Q9BT22,Q9H0U3 4 +Altered glycosylation of muc1 in tumor microenvironment 0.5471808355244037 1.5198245328945337 0.1285550815392802 1.0 0.297273258640549 2 O15111 1 +Canonical nfkb pathway 0.5471808355244037 1.5198245328945337 0.1285550815392802 1.0 0.297273258640549 2 O15111 1 +Envelope proteins and their potential roles in edmd physiopathology 0.5184756937489264 1.4994694745261177 0.1337518819939118 1.0 0.3025698004656283 17 Q9Y2U8,P42167,P50402,O94901 4 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.5717626425022035 1.4268953638671231 0.1536100573789585 1.0 0.3232682556974123 4 P40763,P31751,Q9P2K5 3 +Metapathway biotransformation phase i and ii 0.4616146445924668 1.425593341878917 0.1539857592579978 1.0 0.3232682556974123 22 Q16850,P21964,Q6UW02,Q8NCH0 4 +Nodlike receptor nlr signaling pathway 0.5473407364114481 1.403767754744115 0.160388018901707 1.0 0.3286279736168527 3 O15111,Q96RT1 2 +Supression of hmgb1 mediated inflammation by thbd 0.5473407364114469 1.4037677547441074 0.1603880189017092 1.0 0.3286279736168527 3 O15111,P09429 2 +Fibrin complement receptor 3 signaling pathway 0.5473407364114428 1.4037677547440837 0.1603880189017164 1.0 0.3286279736168527 3 P31749,O15111 2 +Steroid biosynthesis 0.5252702307917064 1.3912749323005642 0.164142072317436 1.0 0.3315779654840514 2 P51659 1 +Ccl18 signaling pathway 0.5622336013776824 1.3399055749916948 0.1802760453959553 1.0 0.3502533459575069 11 Q96GC9,Q86UE4,P08670,P00403 4 +Progeriaassociated lipodystrophy 0.5719815672636666 1.3379106364433286 0.1809255694350036 1.0 0.3502533459575069 9 O75844 1 +Hostpathogen interaction of human coronaviruses apoptosis 0.5560633806949911 1.2585952091988313 0.2081765783406968 1.0 0.3841641681025524 5 Q07820 1 +Sarscov2 b117 variant antagonises innate immune activation 0.498393222319606 1.2320398227640783 0.2179342086908848 1.0 0.3950831721543673 2 O94826 1 +Nephrotic syndrome 0.497703637446514 1.1924626424927671 0.2330798904411601 1.0 0.4082699554404046 15 O75844,Q96D53,Q9BT22 3 +Leptininsulin signaling overlap 0.5064289888953707 1.1683208182048026 0.2426773809966662 1.0 0.4199917997764653 3 P40763,P31749 2 +Monoamine transport 0.5192100700395963 1.1332281880233874 0.2571184396957837 1.0 0.4359316939942286 4 O15127 1 +Endothelin pathways 0.5265719042125949 1.0820343171101734 0.2792372795833004 1.0 0.4620803201871602 9 P16615,P00403 2 +Cholesterol biosynthesis pathway 0.501671104251214 1.0760812340798802 0.2818909275650343 1.0 0.4637598205133375 13 Q14534,Q16850,Q15800,O75845 4 +S1p receptor signal transduction 0.5261395772035342 1.057034818860331 0.2904956968771808 1.0 0.4715574686184354 8 Q9H0H5,Q13510,Q9NRA0 3 +Triacylglyceride synthesis 0.517159863172518 1.0441397800353605 0.2964207234941907 1.0 0.4749021670835309 5 O00116 1 +Metabolic pathway of ldl hdl and tg including diseases 0.4636283961437343 1.0244810871172516 0.3056080994477255 1.0 0.4794475118608473 2 Q8WTV0 1 +Camkk2 pathway 0.5109595674521354 1.0167155015100269 0.3092887892569216 1.0 0.4827142860754022 10 P09601,Q9Y3D6 2 +Somatroph axis gh and its relationship to dietary restriction and aging 0.4618755477651348 1.013997408092682 0.3105839890670063 1.0 0.4834864159702883 2 P31749 1 +Vitamin d metabolism 0.4826074247296376 0.9270734718809164 0.3538883885899113 1.0 0.5264743514982918 4 P28702,P04062,P38435 3 +Intracellular trafficking proteins involved in cmt neuropathy 0.4890677754826216 0.9138272196609686 0.3608076412867418 1.0 0.5315312569199806 11 Q9NR77,P07196,O95140,Q15907 4 +Omega9 fatty acid synthesis 0.5039672457050921 0.8970070792372173 0.3697151395070535 1.0 0.5406972016035358 6 O00767,O95864 2 +Vitamin d receptor pathway 0.4596533490294834 0.880160194607362 0.3787725337751628 1.0 0.5526053391309139 14 Q5VV42,P09493,Q96KA5,Q92604 4 +Spinal cord injury 0.411380670730189 0.860994439468303 0.389241105603769 1.0 0.5544849711902747 19 Q9NQC3,Q08722 2 +Signal transduction through il1r 0.466083125063696 0.834239841331287 0.4041458442615786 1.0 0.5698747270175682 4 Q16539 1 +Amyotrophic lateral sclerosis als 0.4775359034660403 0.82466822691597 0.4095599750353074 1.0 0.5739541181469273 10 Q9BUN8,Q16539,O96008,P20339,P07196 5 +Adipogenesis 0.4178397530634368 0.8101638733073623 0.417845997811062 1.0 0.578850877701563 17 Q9NZ45,O75844,O00767 3 +Interactome of polycomb repressive complex 2 prc2 0.448406898567685 0.7355484171353648 0.4620055643337628 1.0 0.6160074191116838 4 Q9Y2W1,Q9NYF8,Q15022 3 +Heme biosynthesis 0.4535973721157825 0.6946412231911552 0.4872801712985524 1.0 0.6329402655146789 5 P22830 1 +Thiamine metabolic pathways 0.4561093828163247 0.6403315271797602 0.5219570883024534 1.0 0.6623735148205082 6 Q9HC21,O14874 2 +Alzheimers disease and mirna effects 0.2919975695626914 0.6092409022106404 0.5423647726206959 1.0 0.6777492803779503 89 O95197,P05141,P12236,P45880,Q9P2E5,Q9NQC3,P16615,P21796,Q96GC9,P49721,Q92542,P12235,Q9Y277 13 +Joubert syndrome 0.3761643894299446 0.5660501720493035 0.5713596744755693 1.0 0.7014252914293574 18 O43924,O75665,P41208,Q10713 4 +Mitochondrial long chain fatty acid betaoxidation 0.4102116098150925 0.5234500086459433 0.6006611311397858 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0000000000000000000000000000000000000000..385dd164c2d62cbbaea09a339a19b2998b2a8bf5 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpcrs other", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna for targeting cancer growth and vascularization in glioblastoma", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD11", "ABHD16A", "ABI2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG6", "AMFR", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APMAP", "APP", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL5B", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG13", "ATG3", "ATIC", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCKDHA", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BLM", "BLVRA", "BLVRB", "BPTF", "BRCA1", "BRD1", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CASP3", "CASP7", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CEP170", "CEP44", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CISD1", "CKB", "CLASP1", "CLIC1", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA1", "COA3", "COASY", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COQ8B", "COQ9", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRCP", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DARS", "DBI", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAC2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHBP1", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELP3", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERI1", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FAM91A1", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP15", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GABPA", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GBE1", "GCDH", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GID8", "GIGYF2", "GJC1", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2H4", "GTF2I", "GTPBP4", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKG", "ILF2", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGA6", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LEO1", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRP1", "LRPPRC", "LRRC59", "LRRC8A", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LUC7L", "LUZP1", "LZTFL1", "MACF1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MEPCE", "METTL3", "MFAP1", "MFN2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOCS2", "MOGS", "MORF4L1", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYEF2", "MYH10", "MYH9", "MYL6", "MYLK", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND1", "ND5", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NFATC2IP", "NIPBL", "NKRF", "NLRX1", "NME1", "NME3", "NME4", "NONO", "NOP2", "NPC1", "NPC2", "NR2F1", "NR3C1", "NRP1", "NSD1", "NSDHL", "NSF", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OFD1", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OSBPL3", "OTUD7B", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PAXIP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PECR", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLXNA1", "PMPCA", "PMVK", "PNKP", "PNP", "PNPT1", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPM1L", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTMA", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RIF1", "RING1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "RXRB", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARS", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SEC13", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEL1L", "SELENBP1", "SEPT11", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNIP1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPHK2", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRRM1", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR3", "SSR4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX4", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE1", "SYNE2", "TAB1", "TALDO1", "TAOK1", "TAP1", "TARDBP", "TBC1D10A", "TBC1D4", "TBCA", "TBL2", "TCP1", "TDP2", "TECR", "TEDC1", "TELO2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMEM126B", "TMEM165", "TMEM38B", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT2A", "TSC22D3", "TSG101", "TSPO", "TTC19", "TTC26", "TTF1", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWISTNB", "TXNDC15", "TXNDC5", "TXNRD1", "TXNRD2", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE2N", "UBE3A", "UBIAD1", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UPF1", "UQCC2", "UQCR10", "UQCR11", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VASP", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS18", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WDHD1", "WDR1", "WDR34", "WDR5", "WDR73", "WDR74", "WFS1", "WNK1", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ABCD3", "ACAT2", "ACOX1", "ACSL1", "ACSL6", "ADI1", "AGPS", "AIP", "AKT1", "AKT2", "ALG1", "ALG11", "ASAH1", "ASNA1", "ATP2A2", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP7B", "BAK1", "BANF1", "BCKDK", "BCL2L13", "BCLAF1", "CANT1", "CD47", "CDC37", "CDIPT", "CDK2", "CDK4", "CDKAL1", "CERS1", "CERS2", "CETN2", "CHPF2", "CHST14", "CHUK", "CISD1", "CLPTM1L", "COA1", "COA3", "COMT", "COQ8A", "COQ8B", "COQ9", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "CPT1A", "CPT2", "CYB5B", "CYC1", "CYP20A1", "CYP51A1", "DERL1", "DHCR24", "DIABLO", "DMAC2", "DPM1", "EBP", "ECSIT", "EMD", "ERBIN", "ETFDH", "FADS2", "FDFT1", "FECH", "FIS1", "FLAD1", "FOXRED1", "FUT8", "G3BP1", "GALNT1", "GBA", "GGCX", "GLB1", "GM2A", "GNA11", "GNAI3", "GPAT4", "GRB2", "HIGD1A", "HLA-F", "HMGB1", "HMOX1", "HNRNPH1", "HSD17B4", "HSP90AA1", "HTRA2", "ICMT", "IFT52", "IKBKG", "IMPAD1", "LBR", "LEMD3", "LMNA", "LMNB2", "LPGAT1", "MAGT1", "MAPK1", "MAPK14", "MAPK3", "MCL1", "MCU", "MFN2", "MSMO1", "MTAP", "MTDH", "MTOR", "MYEF2", "NAMPT", "NAP1L1", "NCOR1", "NCSTN", "ND1", "ND5", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFAF1", "NDUFAF2", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NEFL", "NPC1", "NSDHL", "OFD1", "PCK2", "PDE6D", "PDSS1", "PDSS2", "PECR", "PFDN5", "PHB", "PHB2", "PKMYT1", "PMPCA", "POR", "PSMB2", "PTPN1", "PXMP2", "RAB11B", "RAB5A", "RACGAP1", "RTN3", "RTN4", "RXRB", "SC5D", "SCAMP2", "SCARB1", "SCD", "SCO1", "SCO2", "SDHB", "SGPL1", "SH3GLB1", "SLC25A13", "SLC25A19", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC30A6", "SLC30A7", "SLC35B2", "SLC39A11", "SLC39A14", "SLC3A2", "SPHK2", "SPTLC1", "SQLE", "STAT3", "SUN1", "SUZ12", "TAP1", "THRAP3", "TIMMDC1", "TMEM126B", "TMEM70", "TMPO", "TOMM40", "TOMM70", "TPM1", "TPM3", "TPM4", "TSPO", "TTC19", "TXNDC15", "UBE3A", "UQCC2", "UQCR10", "UQCR11", "UQCRB", "UQCRC2", "UQCRQ", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json 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sha256:f8697c3ee563c2bbdb3d7c5f07a8b2a2bec072c91d44c1d142c1eb644d61706a +size 194877 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..18fc01d6557b37b38526a82aa828ea512c454603 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "er", "1": "vesicles", "2": "mitochondria", "3": "golgi", "4": "nuclear_membrane"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7d94cd09b0bfb88980183d92fc37b68d5318f73c --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c8acd739162ee78198669bbac3c7de9985a6ecb8f7cb307880c84c2e53da14ac +size 132767 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new 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a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c3834e9b0a25a13c93c5c29d00bcb9e8400fd6e1 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 56 96 5.23251487309067 1.672191934173198e-07 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 1.4049653778088422e-28 0.148662677751522 8.328394317671713e-10 4.341915874688007e-16 2.181711590514077e-30 +vesicles 64 189 2.980211764492451 0.0028804917774276 42.101941747572816 169.6626213592233 0.6789633151163722 0.6006686966705359 14.133870910307197 18.74575061031192 1.1351302778834993 0.3922666308151308 1.0978761079060981e-07 0.815619854466078 0.1145132188316713 0.0097701613234431 3.1314163712265046e-10 +mitochondria 7 11 2.6870582691548046 0.0072084376575514 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 5.074023283755038e-07 0.0017062060788896 5.369271916582234e-06 2.831336309208378e-07 3.028938715404879e-08 +golgi 21 67 2.2826541843540182 0.0224507465405767 15.631067961165048 61.19417475728155 0.6692399314943925 0.523533703348586 6.922582002252161 5.868805558877078 1.075539554450533 0.3729249549278102 0.0006108519627228 1.0 1.0 0.2290317051514284 0.0003527235883921 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d92210f4c1199fb280e0edc706ba1eb7731008c0 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 100.41176470588235 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8e2a178ef226fec8538624db7c32063709e595e1 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1357c4d881b214bba38edff622231491174615f0 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.6817079994817363 5.23251487309067 1.672191934173198e-07 2.84272248524744e-06 2.8427262881114365e-06 96 O00767,Q8N4V1,Q9UKR5,Q96A33,Q9NQC3,Q99640,Q9P2W9,Q12981,O15269,Q9NTJ5,Q15363,O95470,Q9NR31,P27824,Q5J8M3,P46977,Q8N766,P49755,Q86UL3,P00387,Q96GC9,Q8NHH9,Q86Y07,Q969V3,Q96N66,Q9Y5M8,P51572,Q16850,O60499,O15173,O14735,Q6NUK4,Q00765,O75845,Q13190,O75396,O00264,Q14739,Q8NF37,P61026,Q969Q5,O96005,Q15738,Q15041,Q9UM00,Q9H6H4,Q15125,P61019,O95674,Q86W74,Q07065,Q15006,Q9NPA0,Q15392,O00400,Q96HR9 56 +vesicles 0.4279384357290567 2.980211764492451 0.0028804917774276 0.0478560259913296 0.0189376210813681 189 O00767,O15400,Q96A49,Q8N6H7,P49257,Q9UKR5,O75787,P56589,O15269,O43633,Q10713,O15127,Q15363,P62820,O95470,Q5VW38,O43808,O95249,Q15907,P49755,Q86UL3,P11279,P00387,Q92783,P05023,P30825,Q8IZA0,Q969V3,O15258,P60033,O60499,O15173,O14735,O75845,O15155,O75396,O00264,O60749,P13473,Q15392,O96005,Q15738,Q8NF37,P61026,Q9H6H4,Q9UM00,O60476,Q93050,O00400,O43752,Q9H0U4,Q15125,O95674,Q86W74,Q9P253,Q9Y3E0,P61019,Q9UNK0,Q6RW13,Q2M1P5,Q15904,Q9UBQ0,Q9UEU0,Q9Y371 64 +mitochondria 0.8115649941486099 2.6870582691548046 0.0072084376575514 0.115725060893127 0.025092371401019 11 Q9NR31,Q15388,P45880,Q8IWA4,P21796,Q969Q5,Q9Y277 7 +golgi 0.4197327792207934 2.2826541843540182 0.0224507465405767 0.3202377815821205 0.0477078363987256 67 Q8N6H7,O75787,O15127,Q9NTJ5,P62820,Q5VW38,Q9NR31,Q15907,P49755,Q8IZA0,O15258,O14735,Q13190,P61026,Q9UM00,Q9H0U4,P61019,Q9Y3E0,Q6RW13,Q15904,Q9Y371 21 +nuclear_membrane 0.2849588598905857 0.2649390490201269 0.7910564160851683 0.9999999999972428 0.7910564160851683 32 P42167,Q14739,P52292,Q8N6S5,Q9Y2U8 5 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4c910dd7bda26edcf44b73db2800c16b3ec04c3d --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", 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2.376884570046072 0.0174595508384363 5.053398058252427 12.385922330097088 1.3935892727836532 0.1814075830019033 2.0222219603900085 1.786979844553702 1.206053991839631 0.2252292235861566 0.0007104899027746 0.0063255491406275 0.0237627189197599 0.0028478177309091 0.000136356004925 +major histocompatibility complex protein 2 5 2.3187019058846614 0.0204112051210705 1.5 3.104368932038835 0.7022588108926267 0.3871686139818919 0.9230069054849024 0.8162668632527542 1.1568580290510009 0.3073336189656853 0.195115846167058 1.0 1.0 1.0 0.0539281835546241 +transfer/carrier protein 8 15 2.272648028812351 0.0230473988649526 4.33252427184466 11.024271844660197 0.5751131114698911 0.3717158985009051 2.2946984989028927 1.3525930522279908 1.248808855129494 0.3186564966906889 0.0005611866958708 1.0 0.0219975904219434 0.0195244436529747 0.0008083265510004 +amino acid transporter 4 5 2.2188335750045014 0.0264980489093398 1.9951456310679612 4.257281553398058 0.7191216814048915 0.3104355279029646 1.1762106872211882 0.8905220397339731 1.285467922271347 0.3110567625654792 0.0116152577017657 1.0 1.0 0.027832231049335 0.0140126286640228 +transmembrane signal receptor 3 8 1.9992890234515044 0.0455770911213413 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.6048186174331621 1.0 0.2213471409258044 0.6573120021986856 0.6593661810718379 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..95eecce928f155114dd78d5e57c4a650890fb93c --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 162, + "title": "Average number of proteins per term", + "value": 14.382716049382717 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2f2ed4118aaf490122f6af44fd97e92196131db7 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..61c3877c3705c55b9367b03fc78248f4bf26262f --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,45 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +primary active transporter 0.7368471361868254 3.6779954771405414 0.0002350741272065 0.0373703160804196 0.0085635455499777 25 Q6NTF9,Q6P4A7,Q9BUN8,Q8N4H5,Q9GZP9,P35670,O96008,Q15388,O75381,P16615,Q9NS69,Q9Y5J7,P05023 13 +voltage-gated ion channel 0.9824663939216832 3.6008583467270925 0.0003171683537028 0.0500913180587198 0.0085635455499777 3 P45880,P21796 2 +cell adhesion molecule 0.9097283085013173 3.416814768040408 0.0006335837257513 0.0975780666934787 0.0144511980875119 2 Q08722 1 +oxidoreductase 0.5256668140075349 2.9445128107637664 0.0032346355516359 0.4083619798742812 0.0323319919936376 49 O14949,Q86Y39,O95168,Q15067,O96000,Q9BUP3,Q9NX14,Q9Y6M9,P16435,O43676,O43169,P09622,O43674,P56556,O95169,P03915,Q8N4Q0,P00403,Q9Y320 19 +oxidase 0.7444464709772133 2.7909632388034047 0.0052551440501871 0.5741116872657069 0.0323319919936376 16 O75880,P13073,P20674,O75845,P14406,O14548,O43819,Q15800 8 +transporter 0.4642498153985543 2.7861722739186505 0.0053334518466299 0.5795087157977808 0.0323319919936376 61 Q92973,Q99595,Q7Z3B4,Q9Y584,O43681,P53007,O60830,Q92544,O15321,P52292,Q99805,Q8TEX9,Q6NXT4,Q9NR77,Q9Y619,Q9NUN5,Q567V2,Q8N8Q8,Q9H2D1,Q9HD45,O43615,Q15070 22 +mitochondrial carrier protein 0.8648855533742745 2.7734155968150676 0.0055471227950094 0.5938917643929055 0.0323319919936376 7 Q9NZJ7,Q70HW3,Q9Y6C9,Q6NUK1,Q9BSK2 5 +secondary carrier transporter 0.6926404343861274 2.76867782456011 0.005628426149238 0.5992352647844392 0.0323319919936376 19 O75746,O00400,Q9BQT8,O95202,Q9UJS0,Q9Y6M7,Q8N1S5,O14975,Q96H78,Q15043,Q9H936,Q8TB61,Q02978,P55011,Q9UBX3 15 +glycosyltransferase 0.5772956502544553 2.7051049271921443 0.0068282817249112 0.6704329909853037 0.0323319919936376 27 Q9Y673,Q8NAT1,Q9BYC5,P46977,Q6UX07,Q9BT22,Q68CQ7,Q10472,Q8NBN7,Q9H0U3 10 +SNARE protein 0.7188778170634254 2.6451103993894227 0.0081664268349845 0.735097294891836 0.0367489207574306 16 P56962,O95721,O15400,O43752,O95249,Q9UNK0,O60499,O15155,Q13190,Q9NV70,Q9P2W9,Q9UEU0 12 +oxygenase 0.8233699195602281 2.5776480572886404 0.0099475256174965 0.8020157741111584 0.0424078723693274 7 Q16850,Q6UW02,P30519,P09601 4 +galactosidase 0.7192521180251271 2.475019887896944 0.0133228756663785 0.8861430299551885 0.0490482295099454 2 P16278 1 +ATP synthase 0.6070050165421287 2.3915728792488267 0.0167763529059632 0.9354828705978314 0.0554713496251432 21 Q93050,P24539,Q96IX5,P00846,Q9Y487,P56385,P06576,O75947,Q15904,P36542,O75964 11 +membrane traffic protein 0.4293889837545693 2.3915287204094704 0.0167783711829137 0.9355043215578468 0.0554713496251432 70 Q9H6H4,Q9H9E3,P40855,Q96PC5,P51572,P49257,Q96RL7,Q96ED9,O60313,Q00765,Q6NUK4,Q5JRA6,Q9NX40,P43307,Q96HR9 15 +calmodulin-related 0.7256103295194857 2.376884570046072 0.0174595508384363 0.942353754830754 0.0565689447165336 13 P80303,Q02818,Q8IYU8,Q14257,Q9BRK5,P41208,Q99584 7 +aspartic protease 0.6970493718959989 2.357564448250975 0.0183952618865592 0.9505988958706066 0.0584320083455412 2 Q8TCT9 1 +major histocompatibility complex protein 0.7583602068064087 2.3187019058846614 0.0204112051210705 0.964592356870045 0.0623889665964797 5 P30511,P55899 2 +transfer/carrier protein 0.6729306016231893 2.272648028812351 0.0230473988649526 0.977117369203947 0.0683724557880265 15 O15127,Q9Y5M8,P05141,Q5T8D3,P12236,P17900,Q9NZD2,P12235 8 +amino acid transporter 0.7383040935672742 2.2188335750045014 0.0264980489093398 0.9871007085453636 0.0730156733517799 5 P30825,O14925,O75915,O60831 4 +decarboxylase 0.6712362829141925 2.0897290920327145 0.0366421421330296 0.9976362673490694 0.0885974182918029 3 Q9UG56 1 +transmembrane signal receptor 0.7000385120358334 1.9992890234515044 0.0455770911213413 0.9994775815267172 0.1039927994599619 8 Q96GC9,O00264,O15173 3 +acyltransferase 0.5515621975420273 1.8549385916170753 0.0636049962496809 0.9999762112170648 0.13381830379803 19 Q9NUQ2,Q92604,Q643R3,P50416,Q86UL3,Q9BWD1,Q8NF37,P23786 8 +membrane trafficking regulatory protein 0.5389767915318293 1.7004699320761714 0.089042567462592 0.9999997254069468 0.1697046579875284 18 P24390,O00560,O43760,Q14108,P11279,P13473 6 +protein modifying enzyme 0.4456650672972198 1.6482573346883411 0.0992998758860856 0.9999999561473282 0.1807480886915267 27 Q86YN1,Q9UMR5,P50897,Q92791,O60725,Q6PK18 6 +phospholipase 0.6325445432582218 1.5877119395704309 0.1123514919469159 0.999999995878584 0.1957090504881762 6 Q8IV08,Q8N9F7 2 +immunoglobulin superfamily cell adhesion molecule 0.52088810984518 1.3654183141796166 0.1721216109479868 0.9999999999999486 0.2788370097357387 2 P43121 1 +transferase 0.388432296059307 1.2470712992064386 0.2123713555269655 1.0 0.3340209669453243 35 Q2TAA5,Q8NBI6,Q9Y2C2,Q9NXS2,Q99735,Q7LGA3,Q8NCH0,O14735,P37268,Q9Y5Z9 10 +ion channel 0.5589793916494858 1.1950277177916746 0.2320762008304315 1.0 0.342664023637642 6 Q96S66,Q9C0H2 2 +chaperone 0.3309276277753905 1.1774430076572393 0.2390187325373676 1.0 0.342664023637642 73 Q8N183,O15260,O14657,P27824,Q9BRT2,Q9NWM8,Q9Y680,Q7KZN9,Q9GZY4,Q15006,O95433,Q96I36,Q9Y2R0,Q96KC8,Q96JJ7 15 +ATP-binding cassette (ABC) transporter 0.5365562469332974 1.1385191974096422 0.2549037473436921 1.0 0.3565463298635436 9 P28288,P08183,Q03519,Q03518,O75027,P33527 6 +heterotrimeric G-protein 0.534532913234167 1.0626947954996224 0.2879203818376601 1.0 0.3866476875384841 6 Q8NHH9 1 +lyase 0.4873950050545239 1.05447031461105 0.2916676446438655 1.0 0.3872963805926739 14 Q9UHG3,P22830,P53701,Q8NBM8 4 +tight junction 0.4653812445223602 1.0349647679732097 0.3006853652184209 1.0 0.396024627360847 2 Q9UDY2 1 +metalloprotease 0.3664048177496221 0.9516196183198884 0.341289928363893 1.0 0.4388013364678624 26 Q7Z2K6,P22695,Q5JRX3,Q96TA2,Q9NZ08,P42892,P52888,O75844,Q99797,Q10713 10 +kinase activator 0.4652250146113363 0.9293750728941876 0.3526947414538162 1.0 0.4498940796497497 3 Q9Y3A3,O95067 2 +primase 0.4332456909143998 0.8430711194525272 0.3991886697293676 1.0 0.4826012275832653 2 P49643 1 +serine protease 0.3814259596819785 0.7456316787861361 0.4558899409230201 1.0 0.5366852799891684 21 Q7L211,Q2T9J0,Q16740,O43464,Q9HB40,Q8N2K0,O14773,Q9H300,P67812,P10619 10 +kinase 0.374978941756749 0.6000932595133702 0.5484440845104874 1.0 0.626861028412093 19 P52789,Q53H12,Q9BRR6,Q8WVC6 4 +non-motor microtubule binding protein 0.3684149196254415 0.598553341694712 0.549470777990847 1.0 0.626861028412093 20 Q96RT7,Q4ZIN3 2 +vesicle coat protein 0.3059046345737162 0.442430559599437 0.6581776692044352 1.0 0.7156025665175739 31 Q15363,Q9Y3B3,Q7Z7H5,Q12893,P49755,Q9UBQ0,Q9Y3A6 7 +cytoskeletal protein 0.3853688470884315 0.2909111946777912 0.7711192393104906 1.0 0.806688479703648 7 Q14141,P27105 2 +glucosidase 0.3495032144944495 0.2899799583581927 0.7718315700868237 1.0 0.806688479703648 3 Q13724,P10253 2 +C2H2 zinc finger transcription factor 0.3620941795846655 0.1800297468080396 0.8571292151433674 1.0 0.873301464485695 6 Q9Y2X9,Q7Z3K3,O95785,P49711,Q8ND82 5 +G-protein 0.3355514617915193 0.0727019677787646 0.9420432826343036 1.0 0.9538188236672324 6 P40616,Q9NTK5 2 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..efabfb9394abe5647388c5acfe56112c41742643 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "cell junction protein", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "gap junction", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD13", "ABHD16A", "ABHD6", "ABI2", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG5", "ALG6", "ALKBH5", "ALYREF", "AMFR", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APOL2", "APP", "APRT", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARIH1", "ARIH2", "ARL1", "ARL5B", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCKDHA", "BCKDHB", "BCKDK", "BCLAF1", "BET1", "BLM", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCDC94", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CEP170", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNP", "COA1", "COA3", "COASY", "COG4", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "CORO7", "COTL1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRCP", "CRK", "CRKL", "CRMP1", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "ENOPH1", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FNDC3A", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATB", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GGT7", "GID8", "GINS2", "GJC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "ISCU", "ISOC1", "ISOC2", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LENG8", "LEO1", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LNPEP", "LONP1", "LPCAT1", "LPCAT4", "LPGAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRWD1", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MBLAC2", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED17", "MED23", "MED24", "MED25", "MED4", "METAP2", "METTL13", "METTL16", "METTL3", "METTL7B", "MFAP1", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOB4", "MOCS3", "MOGS", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCDN", "NCKIPSD", "NCOA5", "NCOR1", "ND1", "ND5", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NENF", "NHP2", "NIP7", "NIPBL", "NIT2", "NKRF", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PARG", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDZD11", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGL", "PIK3C2A", "PIK3R2", "PIK3R4", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PURB", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB3GAP2", "RABGAP1", "RABL6", "RAC1", "RAC3", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM47", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RNASEH2A", "RNF14", "RNF2", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RXRB", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A6", "SLC30A9", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAP29", "SNIP1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPOUT1", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUFU", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TADA3", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TES", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM9", "TJP1", 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--git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a8c442cc4f8f2558ef91ff076398e42a6d16371c --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 2150, + "title": "Average number of proteins per term", + "value": 3.146046511627907 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bdcf27e1bc07475389448efd78d43796fb9d251b --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2c3a7dd8f1ae2c1f6ad9d691d237621f65b51ace --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,63 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter 0.5384482933121657 4.6705477134691415 3.0039769614020884e-06 0.0064377484965652 0.0018360774485931 216 P28288,Q9Y3B3,Q9BQE5,Q9NZD2,Q9P2W9,Q9Y584,P53007,O95249,Q92544,Q9UJS0,P00846,Q15043,O15321,Q8TEX9,O00560,O60499,Q6NUK4,P17900,Q96H78,Q02978,O60749,Q9Y619,P24539,Q9P253,Q9UHQ4,Q8N1S5,Q9HD45,Q96HR9,Q15070,Q9BSK2,O75746,Q92973,Q9BQT8,P08195,Q7Z3B4,Q9NV70,Q9Y3A6,P24390,O43808,Q12846,Q03518,P49755,Q9BVK6,O75947,Q8TB61,P12235,O60645,P56962,Q9NZJ7,Q00765,Q70HW3,Q9Y6M7,Q9Y487,O75027,P13473,Q9Y6C9,Q12768,Q9UBX3,Q9H6H4,Q96NB2,Q15388,O14975,Q9H2D1,P06576,Q8NEW0,Q9UBQ0,P36542,Q9Y5K8,Q9H0U3,P49257,Q15758,P56385,P11166,O43760,P16615,Q15363,Q8N1F7,O95202,Q8TEM1,Q6PML9,P12236,P11279,P52292,P35670,Q03519,Q13190,Q6NUK1,O00400,Q9UEU0,O15400,Q8TBP6,Q9HC21,Q7Z7H5,O95721,P05023,P30825,Q99805,Q6NXT4,P51572,P05141,O15155,Q93050,O43752,O96008,Q9UNK0,P98194 106 +SLC superfamily of solute carriers 0.6239929286947714 3.9710905916878647 7.15443654477621e-05 0.142578705047212 0.0018360774485931 52 O75746,Q99808,Q8TBP6,P08195,Q9HC21,Q9BQT8,Q15758,P11166,P53007,O43808,O95202,Q9UJS0,Q6PML9,P12236,Q15043,Q8TB61,P12235,P30825,Q9NZJ7,Q6NXT4,P05141,Q9Y6M7,Q70HW3,Q96H78,Q02978,P55011,Q9Y6C9,Q6NUK1,Q9UBX3,Q9Y619,Q96NB2,O00400,Q8NEW0,Q8N1S5,O14975,Q9H2D1,Q9H936,Q9BXP2,Q9H0U3,Q9BSK2 40 +SLC25 family of mitochondrial transporters 0.7715638904561639 3.6548726870070807 0.0002573096331059 0.4249434511850203 0.0019548258345508 23 Q8TBP6,Q9BQT8,Q9HC21,P53007,O43808,Q9UJS0,P12236,P12235,Q9NZJ7,P05141,Q70HW3,Q96H78,Q02978,Q9Y6C9,Q6NUK1,Q9UBX3,Q9Y619,Q9H2D1,Q9BSK2 19 +Miscellaneous SLC25 mitochondrial transporters 0.9360210341805442 3.53838404197981 0.00040258406147 0.5792557063814864 0.002191280334584 2 Q9NZJ7 1 +SLC39 family of metal ion transporters 0.8185801928133214 2.9802043306817856 0.0028805616855978 0.9979749173189004 0.0075069183321639 2 Q15043 1 +Oxidase 0.6963149018818243 2.974406779737089 0.0029355563589887 0.9982013666355416 0.0075767661126361 21 O15260,O75880,P20674,O43169,P14406,O75845,O14548,O43819,Q15800 9 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.8112766579024282 2.944143884646479 0.0032384940202827 0.999064155264498 0.0081435814545121 2 P30825 1 +Mitochondrial nucleotide transporter subfamily 0.8685597189695503 2.87434341993011 0.0040486846707032 0.9998370946148544 0.0095008659625757 9 O43808,Q9HC21,Q70HW3,P12236,Q9H2D1,Q6NUK1,P12235,Q9BSK2 8 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.8254896229172862 2.73914158036287 0.0061599839974137 0.99999830007291 0.0129209420433557 4 P53007,Q9UBX3,Q9BQT8 3 +SNARE protein 0.742240897051712 2.6674637099394514 0.0076426142410859 0.9999999313834896 0.0151091835828364 15 P56962,O95721,O15400,O43752,O95249,O60499,O15155,Q13190,Q9P2W9,Q9UEU0 10 +Calcium-binding protein 0.6731740264596052 2.6482515447017376 0.0080909297690487 0.9999999740281816 0.0157104463619274 19 P60660,P80303,Q02818,Q14257,Q8IYU8,Q9BRK5,P41208,P43307,Q99584 9 +SLC12 family of cation-coupled chloride transporters 0.7405784399649409 2.5862417946243417 0.0097028837725257 0.9999999992132153 0.0179837931990778 2 P55011 1 +Calmodulin 0.7255335687449469 2.573985744934919 0.0100534415256452 0.9999999996324952 0.0184270241092389 15 P60660,P80303,Q02818,Q14257,Q8IYU8,Q9BRK5,P41208,Q99584 8 +Intracellular calcium-sensing protein 0.7255335687449469 2.573985744934919 0.0100534415256452 0.9999999996324952 0.0184270241092389 15 P60660,P80303,Q02818,Q14257,Q8IYU8,Q9BRK5,P41208,Q99584 8 +SLC30 zinc transporter family 0.7632963179427299 2.567326873148664 0.0102485952204971 0.999999999759468 0.0187150335857498 3 Q8NEW0,Q6NXT4 2 +Ca2+-ATPases 0.7618351841028683 2.559961906757886 0.0104683637222784 0.9999999998507824 0.019009275340286 3 P16615,P98194 2 +SLC56 Sideroflexins 0.7309377738825609 2.5361554657212553 0.0112076966017187 0.9999999999700832 0.0199971350155147 2 Q96NB2 1 +F-type ATPase 0.7799181405693452 2.404109966114365 0.0162118957471308 0.9999999999999994 0.0264458086922089 8 P00846,P06576,P24539 3 +PDHK family 0.7115721800116885 2.302413400831081 0.0213118699606522 1.0 0.0327523376807736 3 O14874,Q15118 2 +Na+/K+-ATPases 0.7101110461718252 2.2948031254077037 0.0217444094613308 1.0 0.0332506972559468 3 P54709,P05023 2 +Aspartic protease 0.6972530683810619 2.227528611631699 0.0259119657912658 1.0 0.0381627210080412 3 Q8TCT9,Q5BJF2 2 +Oxygenase 0.7400021467290068 2.227335394538215 0.0259248666823179 1.0 0.0381627210080412 5 Q16850 1 +Signaling 0.5843914666294223 2.154272205394431 0.0312188312527454 1.0 0.0440640490645746 20 Q7Z4V5,Q96PC5,O15173,O00264,Q5JRA6,Q07820,Q96GC9,Q8IZ81,Q96JJ3,Q99627 10 +ABCB subfamily 0.7239766081871549 2.14675548620456 0.0318127528526519 1.0 0.0447041951850991 5 Q03518,P08183,O75027,Q03519 4 +Receptor 0.4855595976746742 2.065350463151059 0.0388898520463356 1.0 0.0525538541166698 32 Q6NTF9,Q9BUN8,Q9GZP9,Q567V2,Q9NR77,P57105,O75787,O75381,Q14108,Q14118,Q9Y639 11 +P-type ATPases 0.7109420713867625 2.0227599448909386 0.0430979032109066 1.0 0.057056953142518 7 P54709,P35670,P20020,P16615,P98194,P05023 6 +F-type and V-type ATPases 0.5795200684371973 1.8029627870109544 0.0713940591451505 1.0 0.0861865327952388 16 Q93050,P24539,P00846,Q9Y487,P56385,P06576,O75947,P36542 8 +CDK1 subfamily 0.5889570552147335 1.761019005227178 0.0782351863333106 1.0 0.0929826703242774 2 P06493 1 +Mitochondrial amino acid transporter subfamily 0.6475622669937409 1.6937198649995755 0.0903185278135356 1.0 0.1042323321519601 7 Q9Y619,Q96H78,Q9UJS0,Q8TBP6 4 +Acyltransferase 0.6092515437411027 1.5757555932476164 0.1150821399632464 1.0 0.1266564366028008 10 Q8NF37,Q9UJ14,Q86UL3,Q643R3 4 +Cytokine 0.5422144317849967 1.4907999545574384 0.136014023720856 1.0 0.1452708152011129 2 P43490 1 +Membrane trafficking regulatory protein 0.4799100304020733 1.489805281912041 0.1362754419235472 1.0 0.1454745050734912 21 P24390,O00560,O60749,O43760,P11279,P13473 6 +Growth factor 0.5975537850563527 1.402271423144234 0.1608342105417253 1.0 0.1693406232442259 6 Q7Z4V5,Q5JRA6,Q96PC5 3 +Immunoglobulin superfamily cell adhesion molecule 0.52088810984518 1.3654183141796166 0.1721216109479868 1.0 0.1796414871544522 2 P43121 1 +ATP-binding cassette transporter family 0.5782101261361843 1.3461898545822435 0.1782412961315134 1.0 0.1856680168036598 8 P28288,P08183,Q03519,Q03518,O75027,P33527 6 +Oxidoreductase 0.3260846871531682 1.3389370062782302 0.1805911811181555 1.0 0.1879337073591647 123 O15260,P21912,O95168,Q8NCN5,O14548,Q9UDW1,O43819,Q9Y6M9,P00374,Q96CU9,Q9P0J0,O43169,P14406,Q13423,P20674,Q16850,Q14534,Q8TED1,O75845,Q8TC12,Q14739,P03886,P03915,P00403,O75880,Q9H7Z7,Q9BY49,Q6ZRP7,Q15392,Q15800 30 +Phosphatase inhibitor 0.5792398547700651 1.304186999660321 0.1921698313313284 1.0 0.1998863751148312 6 P55209,Q99733 2 +Glycosyltransferase 0.4706627642986312 1.2886451731500868 0.1975214712329307 1.0 0.2051551512805802 19 Q8NAT1,Q8N128,P46976,P46977,Q9Y672,Q9P2E5,O60762,Q10471,Q9BT22,Q10472,Q8TCJ2,Q93063,P04844 13 +Reductase 0.4787013075485357 1.2855780281562312 0.198590368930162 1.0 0.2061657620472469 18 O95881,O95168,P14927,Q9H7Z7,P00374,O76062,Q14739,Q15392,Q9UDW1 9 +AMPK subfamily 0.5042360502483347 1.26677786614432 0.2052347285406592 1.0 0.2127553839741646 2 Q13131 1 +Ion channel 0.5473704282344518 1.1995846846216889 0.2303006775486844 1.0 0.2385098539160267 9 Q96S66,P51790,Q9C0H2 3 +Heterotrimeric G-protein 0.534532913234167 1.0626947954996224 0.2879203818376601 1.0 0.2966117972932292 6 Q8NHH9 1 +C2H2 zinc finger transcription factor 0.471499561531712 0.8646251843612425 0.3872445450977451 1.0 0.3964646533143581 4 Q9Y2X9,Q7Z3K3,P49711 3 +KRAB box transcription factor 0.471499561531712 0.8646251843612425 0.3872445450977451 1.0 0.3964646533143581 4 Q9Y2X9,Q7Z3K3,P49711 3 +Phosphatase modulator 0.4770158053946103 0.7833994160325931 0.4333925989791369 1.0 0.4426575238979308 8 P55209,Q99733 2 +Tight junction 0.4484068985676681 0.7355484171352706 0.4620055643338201 1.0 0.4714342493202246 4 Q16625,Q9UDY2,Q07157 3 +Lyase 0.3864307957409231 0.7303039166608907 0.4652044346867106 1.0 0.4744732137459335 20 A1L0T0,P22830,O96005,Q96KA5 4 +Vesicle coat protein 0.3276790700850971 0.6168282250813836 0.5373480328569222 1.0 0.5462403170885971 27 Q15363,Q7Z7H5,P49755,Q9UBQ0,Q9Y3A6 5 +Cell-cell junction 0.4486692015209013 0.6011387278868315 0.5477475905649039 1.0 0.5565488278424118 6 Q07157,Q9UDY2,Q5EBL8,P36383,Q16625 5 +Acetyltransferase 0.3371976366694015 0.4633093890294767 0.6431426168004644 1.0 0.6513220094776252 22 P50416,P23786,Q9BWD1 3 +Zinc finger transcription factor 0.4078408425980099 0.4011732766267499 0.6882925542309684 1.0 0.6963901136925091 7 Q9Y2X9,Q7Z3K3,P41223,O95785,P49711,O94880 6 +Glucosidase 0.3494011101373001 0.36343745998345 0.7162781230227724 1.0 0.7243640472713831 2 P10253 1 +MAPK family 0.3579777907656378 0.3325775328675144 0.7394532050118936 1.0 0.747097927996039 3 Q16539,P27361 2 +G-protein 0.2896611029146621 0.3017900700066376 0.7628121011367752 1.0 0.7699746560770266 31 Q8NHH9,O60313,Q9NTK5,P61225 4 +Metalloprotease 0.2805756353474606 0.2719615568720414 0.7856515787458842 1.0 0.7919132181451716 40 Q9NXS2,P22695,Q9NZ08,O75844,Q10713 5 +Extracellular structure 0.354162865722627 0.1592563310297245 0.8734669243744748 1.0 0.8787804807698272 9 Q92791,O75718,P55081 3 +Phosphatase 0.2662695650797738 0.1298971362307681 0.896647810049755 1.0 0.9016804450921296 38 Q86YN1,O95140,Q5SGD2,Q8IWA4,Q9NPH0,Q9NX62,O43681 7 +Nucleotide phosphatase 0.3411246804774965 0.1026709751281475 0.9182241103690444 1.0 0.9229461604924944 9 Q8IWA4,O43681 2 +Esterase 0.3347764676010435 0.0856592877572817 0.93173726678703 1.0 0.9360911792486516 11 Q9UMR5,P50897 2 +Kinase activator 0.3269005847953282 0.0805045822327805 0.93583595197124 1.0 0.9397698723671958 5 P14635,Q9Y3A3,Q16543,O95067 4 +Non-motor microtubule binding protein 0.3007589486192166 0.0700941340967155 0.9441187355332208 1.0 0.9476448559273692 17 Q96RT7 1 +Atypical group 0.30731841848566 0.0096355750403859 0.992312042404851 1.0 0.9955533789876014 5 O14874,Q15118 2 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..598be51138377762810a5f33f1d55325e5bbedfb --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S12, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S21, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-Ketosteroid receptors", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L27, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-1A", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 2", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-CoA-binding protein", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyltransferase and sulfurtransferase MOCS3", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Amyloid-beta A4 protein", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Arylsulfatase A", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "B-cell receptor-associated protein 29", "B-cell receptor-associated protein 31", "BET1 homolog", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beta-adducin", "Beta-arrestin-2", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bis(5'-adenosyl)-triphosphatase ENPP4", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 4", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-3", "Caspase-7", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell surface glycoprotein MUC18", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chondroitin sulfate glucuronyltransferase", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collagen type IV alpha-3-binding protein", "Collectin-12", "Condensin complex subunit 1", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Coronin-7", "Coup transcription factor 1", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidylate deaminase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-2", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 1", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Down syndrome critical region protein 3", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "Dystroglycan", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase XIAP", "EF-hand domain-containing protein D2", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enolase-phosphatase E1", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Estradiol 17-beta-dehydrogenase 8", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FAK family", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Focal adhesion kinase 1", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GA-binding protein alpha chain", "GDP-L-fucose synthase", "GDP-mannose 4,6 dehydratase", "GEK subfamily", "GHMP kinase family", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Gamma-tubulin complex component 6", "Ganglioside GM2 activator", "Gap junction", "Gap junction gamma-1 protein", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIH subunit 4", "General vesicular transport factor p115", "Glia maturation factor beta", "Glucocorticoid receptor", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutaminyl-peptide cyclotransferase-like protein", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione hydrolase 7", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycolipid transfer protein", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock factor protein 1", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Hepatoma-derived growth factor-related protein 3", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone deacetylase complex subunit SAP30", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit beta-1", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 1", "Inositol monophosphatase 3", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIF7", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Lethal(3)malignant brain tumor-like protein 2", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysophospholipid acyltransferase LPCAT4", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase inducer phosphatase 3", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAPK family", "MARK subfamily", "MCU family", "MFS-type transporter SLC18B1", "MLCK family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metallo-beta-lactamase domain-containing protein 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Mevalonate kinase", "Mevalonate kinase subfamily", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim10 B", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light chain kinase, smooth muscle", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADH-ubiquinone oxidoreductase chain 5", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Nf-kappa-b essential modulator", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase, mitochondrial", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Occludin", "Opioid growth factor receptor", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 3", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PDZ domain-containing protein 11", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PKA family", "PKC alpha subfamily", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal leader peptide-processing protease", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SLU7", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein ABHD16A", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein Hook homolog 2", "Protein LSM14 homolog B", "Protein NDRG1", "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A11", "Protein S100-A13", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein SET", "Protein Wiz", "Protein XRP2", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c alpha type", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase 1L", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec24D", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "RNA polymerase-associated protein LEO1", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related C3 botulinum toxin substrate 3", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor expression-enhancing protein 6", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoic acid receptor rxr-beta", "Retinoid X receptors", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC18 family of vesicular amine transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Septin-10", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tao1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 25 member 44", "Solute carrier family 35 member F1", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-10", "Syntaxin-12", "Syntaxin-17", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAO subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10A", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 8B", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TNF receptor-associated factor 2", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin reductase 2, mitochondrial", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 9B", "Transcriptional activator protein Pur-alpha", "Transcriptional activator protein Pur-beta", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 1", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm5", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 22", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 4", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VIP36-like protein", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 72 homolog", "Vacuole membrane protein 1", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle transport through interaction with t-SNAREs homolog 1B", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 34", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 6", "Zinc transporter 7", "Zinc transporter 9", "Zinc transporter ZIP11", "Zinc transporter ZIP14", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ABI2", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG6", "ALYREF", "ANAPC1", "ANGEL1", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARIH1", "ARIH2", "ARPC1A", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BAG6", "BAIAP2", "BAK1", "BCAP29", "BCAP31", "BCAS2", "BCKDHB", "BCKDK", "BCLAF1", "BET1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CEP170", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNP", "COASY", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRMP1", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBNL", "DBT", "DCAF13", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSCR3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP4", "FKBP5", "FMR1", "FNTB", "FOXRED1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GBE1", "GCAT", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GID8", "GINS2", "GJC1", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2H4", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HPRT1", "HSD17B10", "HSD17B8", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKG", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEO1", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LPCAT1", "LPCAT4", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS2", "MAT2A", "MBLAC2", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED25", "METTL7B", "MFAP1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MOCS3", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS12", "MRPS16", "MRPS2", "MRPS21", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYLK", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCBP1", "NCL", "NCOA5", "NCOR1", "ND1", "ND5", "NDRG1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4", "NEDD4L", "NEK9", "NHP2", "NIPBL", "NKRF", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OGFR", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDZD11", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R2", "PIK3R4", "PIR", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPP1CA", "PPP1CB", "PPP1CC", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPRF", "PUDP", "PUM1", "PURA", "PURB", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RAC1", "RAC3", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RNASEH2A", "RNF14", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RXRB", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC35F1", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLK", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPHK2", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "STAG1", "STAG2", "STAT1", "STAT3", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TAOK1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM10B", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TM7SF2", "TM9SF1", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM165", "TMEM259", "TMEM38B", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TXNRD2", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBIAD1", "UBP1", "UCHL5", "UCK2", "UGGT1", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP14", "USP15", "USP19", "USP22", "USP28", "USP39", "USP4", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VMP1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR74", "WDR82", "WIZ", "WNK1", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM4", "ZNF281", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD3", "ACAT2", "ACP6", "ALG1", "ALG6", "APOL2", "ASNA1", "ATL2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7B", "BCAP29", "BCAP31", "BCKDK", "BET1", "BUD31", "CCNB1", "CCNB2", "CDC37", "CDK1", "CETN2", "CHPF2", "CLCC1", "CLCN3", "CLPTM1", "CLPTM1L", "COPS8", "COX2", "COX5A", "COX7A2", "COX7A2L", "CPT1A", "CPT2", "CRTAP", "CTCF", "CYB5B", "CYP51A1", "DAG1", "DERL1", "DERL2", "DHCR24", "DHFR", "DOLPP1", "DPM1", "ELMO2", "ELMOD2", "ERAP1", "EXOC1", "EXOC3", "EXT2", "FAM177A1", "FECH", "FOXRED1", "GAA", "GALNT1", "GALNT2", "GGT7", "GJC1", "GLTP", "GM2A", "GOSR1", "GPAT4", "GPX8", "GYG1", "HDGFL2", "HM13", "ILVBL", "IMPAD1", "IPO4", "KDELR1", "KPNA2", "LAMP1", "LAMP2", "LBR", "LETM1", "LMAN1", "LPCAT1", "LPCAT4", "MAGT1", "MAPK14", "MAPK3", "MCAM", "MCL1", "MFAP1", "MFN1", "MFN2", "MIA2", "MIA3", "MICU2", "MOB4", "MPV17L2", "MSMO1", "MTCH1", "MTCH2", "MYL6", "NAMPT", "NAP1L1", "NAP1L4", "ND1", "ND5", "NDUFA13", "NDUFB4", "NDUFB9", "NNT", "NPTN", "NUCB1", "NUCB2", "NUP210", "NUP54", "NUP93", "OCLN", "OLA1", "OPA1", "OXA1L", "P3H4", "PDK1", "PDPR", "PDZD11", "PECR", "PEX14", "PGRMC1", "PGRMC2", "PHF14", "PMPCA", "POGZ", "POMGNT2", "PPM1L", "PPT1", "PPT2", "PRKAA1", "PTGES2", "PXMP2", "QPCTL", "QSOX2", "RAP2B", "RCN2", "RDH11", "REEP3", "REEP4", "REEP5", "REEP6", "RHBDD2", "RPN2", "S100A13", "SC5D", "SCARB2", "SCO1", "SCO2", "SDCBP", "SDF4", "SDHB", "SFXN2", "SLC12A2", "SLC12A9", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SNAP29", "SNX2", "SQLE", "SSR1", "STT3A", "STT3B", "STX10", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "SURF4", "SYNGR2", "SYNJ2BP", "TAP1", "TAP2", "TIMM22", "TJP1", "TJP2", "TM7SF2", "TM9SF1", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM97", "TNPO1", "TOMM20", "TOMM40", "TTYH3", "TUBGCP6", "TXNDC12", "UQCR10", "UQCRB", "UQCRC2", "VMP1", "VPS18", "VPS29", "VTI1B", "WASHC5", "WIZ", "ZMPSTE24", "ZNF281"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5caa491b9aa6e04692523f9ba93639712ee5eb71 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e07bd68cbeb057282ab7855e83f020b691fa1f6a --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:97f239e956996e6ff5cd1437c52daeeeb2a5df5d72bfad09372517b713ee3b60 +size 205884 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..61535a796704ebaa5615648b4b855d9c5c3c7f08 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark", "1": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1a85031811a2adee3e990e2c96c3d33cba7f9cba --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9c2446d761320e8d75fedd77499a7a34be8e06aaecb8d4d1f9ba5688035fcbe3 +size 136414 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f1c77e84074f82f15353be773698e25dee069310 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:475c9f15407a2b4edd37fd24ce2c3c28aed5467b2e7099b30a4d8ec3b0e9c1d8 +size 135344 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1c17c1d668b9967b93e8b3aeac8f3b59d0113d16 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c1daff6bbc671a14df0d922a2ce741257c05a1b98fc60fff8c4430face3cde59 +size 79018 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2c5b8a301d325d2d38b6d1e3cc44e6ffcc70560e --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tdark 129 369 4.383699413916488 1.1668074200610334e-05 74.3131067961165 324.373786407767 0.5859664552431031 0.6577158703271868 20.515717939687796 49.369088361677456 1.229854636263473 0.4013924214985833 0.9378343621657228 0.060234705498977 0.188913609511196 0.6177555318807848 0.9648755805028624 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..eb39927200b89d4abb49bf4af8dedc4985bab769 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 856.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..470a0b0b0beead3f0251a7a5e60109f2ce8e4f25 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..941cbdf4a2ac7143ea8f58779210818716f376f9 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tdark 0.4399669111768126 4.383699413916488 1.1668074200610334e-05 4.667147994506617e-05 4.6672296802445336e-05 369 Q86YN1,Q8N4H5,Q8N4V1,Q8NBM8,Q8NC54,Q96M27,Q9UKR5,Q9Y3B3,Q96EX1,Q96J42,Q96ND0,Q8IWB1,Q9NRG7,Q9NWR8,Q9Y2W6,Q9NX00,Q96DE5,Q6UW02,Q69YU5,O60830,O75935,Q4G148,Q5J8M3,O95873,Q5SWX8,Q96DB5,P14406,Q6NUQ4,P84157,O15321,Q9H4I3,Q6ZXV5,Q3SXM5,Q9Y5M8,Q6P087,Q8WVI0,Q96H78,Q9BWH2,O75964,Q52LJ0,Q8N5N7,Q8WVC6,Q96CP7,Q643R3,Q9BYN8,Q9Y3E0,Q9NRY5,Q8WZA0,Q9HD45,Q9NPA0,Q96SY0,O14957,Q15005,Q70UQ0,Q9H1E5,Q96A49,Q5BJH2,Q96IX5,O95070,Q8WUJ1,Q9Y6I9,Q9P260,Q6PK18,Q6PI78,Q5VW38,Q9Y4Y9,Q5VWJ9,Q92575,Q5SNT2,L0R6Q1,Q9BVK6,Q9BVG4,Q96CN7,Q9NX62,Q8NC44,Q9H330,Q9BTE7,Q96F63,Q9P0S9,Q8WZA9,Q9UH62,Q8N6S5,Q96TA1,Q9Y6X3,Q7Z2K6,Q9Y320,Q96NB2,Q6YN16,Q9NPL8,Q8IUX1,A4D1U4,Q8NBN7,Q8N128,Q7Z3D4,Q9NW68,O95302,Q96ER9,O94919,Q5HYI7,O75071,Q7Z4Q2,Q8N8L6,Q96BQ5,Q6UX07,Q9H1A3,Q9HD20,Q8WWC4,Q9UNL2,Q96S52,Q9NU23,Q15006,Q86VR2,O43615,Q8IYS2,Q9HC38,Q68D91,Q8TBP6,Q9NQE9,Q6UW68,Q96SK2,Q96LJ7,Q15629,Q99805,Q9NR77,O15155,Q6IAN0,O60476,P62312,Q9BRJ2 129 +Tclin 0.3260997283819031 1.1036309540222535 0.2697532580176354 0.7156334479902712 0.3596710106901805 96 Q8N183,Q9Y375,Q86Y39,O43676,O95168,P00374,P00813,Q9P0J0,O95139,P03915,O96000,P03886,O43924,P49721,P21964,Q9Y6M9,P05023,O95167 18 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fa4d5183448e8479f887f6198fa9d75978bec32f --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD13", "ABHD16A", "ABHD6", "ABI2", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG5", "ALG6", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD46", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf50", "C2orf49", "C5orf15", "C5orf22", "C5orf24", "C6orf47", "C8orf33", "CAB39", "CABLES1", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC59", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CD81", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPH", "CENPI", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMC2", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "CNTLN", "COA1", "COA3", "COA7", "COASY", "COG4", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1C", "CORO7", "COTL1", "COX14", "COX15", "COX18", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRCP", "CRK", "CRKL", "CRMP1", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM210A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTB", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GJC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPX8", "GRAMD4", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IBTK", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPA1", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS4", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1211", "KIAA1468", "KIAA1671", "KIAA2013", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED17", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL16", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS2", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NENF", "NES", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OFD1", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACS1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX11A", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTMA", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETREG2", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAI", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F1", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMIM8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUFU", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THEM6", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM128", "TMEM14C", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF1", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP6", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TXNRD2", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", 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b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2e31d6c7a89225a7f53813a3cfbdd0b0b6743a83 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 174, + "title": "Average number of proteins per term", + "value": 31.660919540229884 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..073dde7860ff5486e198446426bf24aa89b358ce --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d3d2d605f650dac265a115006538033b212a995d --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,55 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.5042484526103741 6.505107342172378 7.763792158200261e-11 1.3508998438546338e-08 1.3508998529268452e-08 544 O14949,Q86Y39,P28288,Q8N4H5,Q8N4V1,Q4KMQ2,Q8N6H7,Q9Y3B3,Q99595,Q9BQE5,Q9NWR8,Q9NS69,Q9NZD2,Q9P2W9,Q9UDW1,Q9NX14,Q9Y584,Q9Y6M9,O43633,P53007,O43676,P62820,O60830,O95197,O95249,Q5T8D3,P00846,Q9UJS0,O43169,Q9Y5L4,P45880,Q13505,Q15043,P21796,P41208,P20340,Q9BTX1,Q5BJH7,Q92783,Q9Y277,O00461,O95864,O95169,Q9BUR5,Q8TEX9,Q9Y282,O60499,Q96H78,Q9Y5J7,Q02978,O60749,Q969Q5,O75964,O95167,P00403,Q9Y619,Q9NUN5,Q9H4L5,P24539,O75431,Q9H0U4,Q9P253,Q9Y3E0,Q9UHQ4,Q8N1S5,Q12893,Q8N5M9,O14957,Q15904,Q9UNH7,Q9BSK2,O75746,Q9H1E5,Q92973,P46379,Q9BQT8,Q9Y241,O14925,P08195,O95070,O96000,Q9Y5J9,O95235,Q7Z3B4,Q9NV70,Q9P260,Q12981,Q9Y3E7,Q9HCU5,Q9Y3A6,Q9UID3,Q96RQ1,Q9NR31,P24390,O43808,P22695,P49069,Q5VWJ9,Q15907,Q12846,Q03518,P49755,Q9H3N1,Q9BVK6,O75947,Q8TB61,O43674,Q96AQ8,Q96AA3,P12235,P56556,P56962,O60645,Q9HD47,Q9C0H2,Q9NZJ7,Q9BZF3,Q9Y6M7,Q70HW3,O14828,Q9Y487,Q96S66,Q9H4A6,O75027,P03886,Q9UGP8,Q9Y6C9,Q12768,Q9UBX3,O60831,Q96NB2,Q15388,P20339,Q2M389,Q96DA6,A0FGR8,Q07955,Q9UI09,Q9H2D1,P06576,P36543,Q8NEW0,Q9UBQ0,P36542,Q9BSJ8,Q9Y5K8,Q9H0U3,P21912,P49257,Q15758,P56385,P60468,P50416,P11166,P16615,Q99442,Q9BPX6,Q9NP72,Q9NRG9,P23786,Q99584,O43681,Q8IUD2,P61020,Q15363,O95219,Q96ER9,P47985,Q8N1F7,O95202,Q5HYI7,Q96CU9,Q9P0J0,Q9Y3C0,Q96PU8,Q8TEM1,P12236,Q6PML9,P52292,P35670,Q03519,Q96RL7,Q13190,Q9HD20,P61026,Q6NUK1,Q9UM00,Q6P4A7,Q9BUN8,O75381,O43615,O00400,Q9UEU0,O95168,Q8TBP6,Q9HC21,Q9Y5U9,P51790,Q14728,Q7Z7H5,Q969X5,Q6DKK2,O15127,O95721,Q3ZCQ8,Q96ED9,O95139,P05023,Q15629,P30825,Q6NXT4,P51572,P05141,O15155,O75396,Q9NQ11,Q8NFH5,Q8NE01,P03915,P08574,Q93050,P14927,O43752,O96008,P61019,Q9UNK0,O15118,Q5JRA6,P98194 229 +Electron transport 0.6427503293294321 4.250339825036861 2.134464298442218e-05 0.003707119121086 0.0018569839396448 54 O14949,Q9H1E5,Q86Y39,O95168,P21912,Q9Y241,O96000,Q9NX14,Q9UDW1,Q6DKK2,Q9Y6M9,O43676,P22695,Q96CU9,Q9P0J0,O95139,O43169,Q9H3N1,O95864,P03886,P03915,P08574,O95167,P00403,P14927,O14957 26 +Ion transport 0.5899128547303988 4.043972233171394 5.255314595387084e-05 0.0091028040117496 0.0022717576555172 61 Q4KMQ2,P51790,P56385,Q9NWR8,P16615,Q9BPX6,Q96ER9,O95202,Q6PML9,P00846,P45880,P20020,Q15043,O75947,P21796,Q96AQ8,P05023,Q9Y277,Q9C0H2,P35670,Q6NXT4,Q9Y6M7,Q9Y487,Q96S66,Q8NE01,P55011,O75964,Q9UM00,Q93050,Q9H0H5,Q8NEW0,P24539,O96008,Q8N1S5,P36543,P06576,P98194,Q15904,P36542,Q9Y5K8 40 +ER-Golgi transport 0.5729829915610539 3.880018249231364 0.0001044486278398 0.0180108410340117 0.0022717576555172 58 Q8N6H7,P49257,O95070,Q969X5,Q9P2W9,Q12981,Q96RQ1,Q15363,P62820,Q9NR31,P24390,O95197,O95249,P49069,P49755,P56962,Q9Y282,P51572,O15155,O75396,P61019,Q5JRA6 22 +Respiratory chain 0.6571058822958576 3.7166920317606422 0.0002018482360734 0.0345154102766642 0.0027016610059068 41 O14949,Q86Y39,O95168,Q9Y241,O96000,Q9NX14,Q9UDW1,Q6DKK2,Q9Y6M9,O43676,P22695,Q96CU9,Q9P0J0,O95139,P03886,P03915,P08574,O95167,P00403,P14927,O14957 21 +Protein transport 0.438484753527605 3.5418084782529142 0.0003973938955694 0.0668229021652191 0.0038414743238382 270 Q8N4H5,Q8N6H7,Q9Y3B3,Q99595,Q9NS69,Q9P2W9,Q9Y584,O43633,P62820,O60830,O95249,Q9Y5L4,Q13505,P41208,P20340,Q9BTX1,Q5BJH7,Q92783,Q8TEX9,O60499,Q9Y5J7,O60749,Q969Q5,Q9H0U4,O75431,Q9P253,Q9Y3E0,Q9UHQ4,Q12893,Q8N5M9,Q9UNH7,Q92973,O14925,O95070,Q9Y5J9,O95235,Q7Z3B4,Q9NV70,Q9Y3E7,Q9HCU5,Q9UID3,Q9Y3A6,Q9NR31,P24390,Q5VWJ9,Q15907,Q03518,P49755,Q9BVK6,O60645,Q9HD47,O14828,Q9H4A6,Q9UGP8,Q12768,O60831,Q15388,P20339,Q2M389,Q96DA6,Q9UBQ0,P49257,P60468,Q99442,Q9NP72,Q9NRG9,Q99584,Q8IUD2,P61020,Q15363,O95219,Q8N1F7,Q9Y3C0,Q5HYI7,Q8TEM1,P52292,Q03519,Q96RL7,Q9HD20,P61026,Q9BUN8,O75381,O43615,Q9UEU0,Q9Y5U9,Q7Z7H5,O15127,O95721,Q3ZCQ8,Q96ED9,Q15629,P51572,O15155,O75396,Q8NFH5,O43752,O96008,P61019,Q5JRA6 99 +Translocation 0.5368971480089098 3.1915735102299987 0.0014150009908759 0.2183783903960158 0.0074609143155279 52 O14925,P60468,Q9Y5J9,Q99595,Q7Z3B4,Q99442,Q9NS69,Q9NRG9,Q9Y584,O60830,Q8N1F7,Q3ZCQ8,Q8TEM1,Q9Y5L4,P41208,Q9BTX1,Q15629,Q9Y5J7,Q8NFH5,Q96DA6,O75381,O43615 22 +Hypusine biosynthesis 0.8022202746129146 2.899197150292975 0.0037411957129469 0.4790956269829094 0.0150818799393907 2 Q9BU89 1 +Peptide transport 0.7995910020449977 2.886099664827793 0.0039004861912217 0.4933889092378193 0.0150818799393907 2 Q03519 1 +Autophagy 0.554784469651137 2.709502919473001 0.0067384112112014 0.6916290153065736 0.0209372062633759 35 P56962,O95721,P62820,Q8N5K1,P13473,Q9Y371,Q9H0U4,Q5T8D3,O95140,O14681,Q9Y6I9,Q96GC9,O15321,Q969Q5,Q9BXS4 15 +Sensory transduction 0.8429185606666505 2.6329393869949143 0.0084649452544141 0.7721732689461488 0.0239472460780013 6 O43924,Q9H6K4,P50897 3 +Vision 0.8429185606666505 2.6329393869949143 0.0084649452544141 0.7721732689461488 0.0239472460780013 6 O43924,Q9H6K4,P50897 3 +Sterol metabolism 0.5618903260321184 2.6263422385364734 0.0086307990672174 0.7787091235903185 0.0239472460780013 29 P04062,O75477,Q15125,Q9UKR5,Q16850,O15118,O94905,O75845,P37268,Q14739,P00387,Q15800,Q15392,Q15738 14 +ATP synthesis 0.8225698148589897 2.612478765978288 0.0089888275992966 0.7921893453260442 0.0242912439505424 8 O75964,P00846,P06576 3 +Apoptosis 0.3970968483782834 2.584315440072583 0.0097572509939012 0.8184272159428135 0.0254916073906579 132 Q6IC98,P46379,Q9NR28,Q96A26,Q9H2J4,Q14728,Q9BXK5,P05067,O96013,Q9BUP3,Q12981,Q9UHX1,Q96KA5,O95470,Q5J8M3,O95197,Q9P0J0,P09601,O14737,P12236,Q6NUQ4,O60566,P21796,Q9NZJ7,P51572,Q9UDX5,O60313,Q15041,Q9Y3D6,P61289,Q9H3K2,O95140,Q9UHQ4,O14681,Q07820,Q96JJ3,Q9Y371 37 +GPI-anchor biosynthesis 0.8316836691396299 2.5802679428388684 0.0098723682616848 0.8220633408449145 0.0254916073906579 6 Q9Y2B2,Q9H490,Q96S52,O43292 4 +Steroid metabolism 0.5529737326861305 2.5771372897742353 0.0099622373710617 0.8248515706739405 0.0254916073906579 30 P04062,O75477,Q15125,Q9UKR5,Q16850,O15118,O94905,O75845,P37268,Q14739,P00387,Q15800,Q15392,Q15738 14 +Steroid biosynthesis 0.5572143912214581 2.534139728330823 0.011272377327439 0.8608958330785528 0.0281022958723986 26 Q15125,Q9UKR5,Q16850,O75845,Q53GQ0,P37268,Q8NBQ5,Q14739,P00387,Q15800,Q15392,Q15738 12 +Peroxisome biogenesis 0.8006296260947134 2.5252904192203154 0.0115602711545679 0.8677689144147749 0.0283308053647157 5 P40855,O75192,O14734 3 +Sphingolipid metabolism 0.7909471735603788 2.497774252086378 0.0124975752325504 0.8878906847140293 0.0297887409652572 9 O95470,P04062,P07602,O15269,Q13510 5 +Antiport 0.7986815595726715 2.423532020800665 0.0153703981573045 0.93247220747658 0.0361412064779864 6 O95202,P51790,P12235,P12236 4 +Cholesterol metabolism 0.5410855356686596 2.409765135848074 0.0159627928007253 0.9391858786762128 0.0370336792976827 26 P04062,O75477,Q15125,Q16850,O15118,O94905,P37268,Q14739,P00387,Q15800,Q15392,Q15738 12 +Hydrogen ion transport 0.6130077457438484 2.345816099213551 0.0189854723152023 0.9643937402782776 0.0428432739347421 20 Q93050,P24539,P00846,Q9Y487,P56385,P36543,O75947,P06576,Q15904,P36542,O75964 11 +Zinc transport 0.7637426900584849 2.3453002385096293 0.0190117632425239 0.9645593934203937 0.0428432739347421 5 Q8NEW0,Q15043,Q6NXT4,Q8N1S5 4 +Calcium transport 0.7588386302503884 2.3367568383161608 0.019451831269222 0.9672211033693416 0.0428432739347421 9 O95202,Q9BPX6,Q9NWR8,P16615,P98194,Q96AQ8,Q9UM00 7 +Sodium/potassium transport 0.7101110461718252 2.2948031254077037 0.0217444094613308 0.9781874270465816 0.0472940905783945 3 P54709,P05023 2 +Sugar transport 0.7230406986224275 2.2328862129186535 0.0255564489996444 0.9889423378276592 0.0535761701920258 4 P11166,Q96AA3 2 +Sterol biosynthesis 0.5933962512950012 2.2149993339555127 0.0267601102380234 0.9910820968763046 0.05543165692162 20 Q15125,Q9UKR5,Q16850,O75845,P37268,Q14739,P00387,Q15800,Q15392,Q15738 10 +Amino-acid transport 0.7322212467076551 2.1647010790604555 0.0304105844005622 0.995362449291956 0.0595243273341788 8 P30825,Q6P4A7,Q96QD8,Q96NB2,P08195,Q15758,Q96H78 7 +Unfolded protein response 0.7251153103839413 2.164234570802544 0.0304463513375972 0.9953921212867254 0.0595243273341788 9 Q9BUN8,Q9GZP9,O95140,Q96CS3,Q15629 5 +Phagocytosis 0.6895432758063442 2.060362545623381 0.039363894705398 0.999076898297371 0.0744491052036875 4 Q96JJ3,P20339 2 +Sodium transport 0.7107341327873665 1.9907793757002925 0.0465051477366873 0.999748004159388 0.0834216052183876 6 P54709,Q96QD8,Q9Y6M7,P55011,P05023 5 +Phospholipid metabolism 0.550565725495412 1.8481406494907189 0.0645819985988211 0.9999909843746276 0.1090996869533484 19 Q96BW9,Q96N66,Q9NUQ2,Q92604,Q643R3,O95674,Q9UG56,O14735,Q86UL3,Q9NPH0,Q8NF37 11 +Cholesterol biosynthesis 0.5696018191874742 1.83817715561617 0.0660363048645813 0.9999931226823296 0.1100084105827288 17 Q15125,Q16850,P37268,Q14739,P00387,Q15392,Q15800,Q15738 8 +Symport 0.6746635459332905 1.8358193025228868 0.0663843856964743 0.9999935545903146 0.1100084105827288 7 Q96QD8,Q15758,Q9Y6M7,Q9H936,P55011,Q00325 6 +Lipid biosynthesis 0.3804612954819297 1.828592112037344 0.0674607352463618 0.9999947267290772 0.1107374333289336 64 O00767,P27544,Q92604,Q9UKR5,Q96G23,Q53GQ0,O76062,P37268,Q96BW9,Q6Y1H2,Q86UL3,P00387,O95864,Q96N66,Q16850,Q9UG56,O14735,O75845,Q8NBQ5,Q14739,Q9P035,Q8NF37,Q15738,Q9NUQ2,Q643R3,Q15125,O95674,Q9H7Z7,Q9BY49,O00116,Q15392,Q15800 32 +Ubiquinone biosynthesis 0.6537908636553191 1.7848411673180018 0.0742870837430647 0.9999985314786382 0.1186409359638608 5 Q8NI60,O75208,Q9Y5Z9 3 +Lipid transport 0.4795248225657451 1.7275911241612336 0.084061555231514 0.9999997684023616 0.128304479037574 24 Q9BUR5,Q4KMQ2,Q9H4L5,Q9BZF3,O15118,A0FGR8,Q9BQE5,Q9NZD2,Q9P260,Q9UID3 10 +Phospholipid biosynthesis 0.5192778525067452 1.5664336224483968 0.1172471367904457 0.999999999623288 0.1686033206738641 18 Q96BW9,Q9NUQ2,Q96N66,Q643R3,Q92604,O95674,Q9UG56,O14735,Q86UL3,Q8NF37 10 +Potassium transport 0.6148943388062351 1.4945192583150757 0.1350399521594094 0.9999999999891028 0.1879756134058979 6 P55011,P54709,Q96ER9,P05023 4 +Notch signaling pathway 0.6125456465276008 1.4820632980622672 0.1383234533229114 0.9999999999943778 0.19101810220783 6 Q92542,Q9UBV2 2 +Heme biosynthesis 0.5549439108954529 1.1944483539744155 0.2323026317258514 1.0 0.2907961001460298 7 P22830 1 +Methionine biosynthesis 0.5068681578310249 1.0637424532632118 0.2874453869781974 1.0 0.3547198392496904 4 Q9BV57 1 +Lipid metabolism 0.3004872647767217 1.006722464519273 0.3140681635871638 1.0 0.3821528703787867 137 O00767,P04062,O14734,P27544,Q92604,Q15067,Q99735,Q9UKR5,Q96G23,O76062,Q53GQ0,P50416,P37268,O15269,P23786,O95470,Q96BW9,Q9H6V9,Q6Y1H2,P07602,Q86UL3,Q9NPH0,P51648,P00387,A1L0T0,Q13510,O95864,Q96N66,Q9UKU0,O75477,Q16850,Q9UG56,O94905,O14735,P17900,O75845,Q8NBQ5,Q14739,Q9P035,Q8NF37,Q15738,Q9NUQ2,Q643R3,Q15125,O95674,Q9H7Z7,Q8NHP8,O15118,Q9BY49,O00116,Q15392,Q15800,Q8NCG7 53 +Biomineralization 0.4589541338007586 0.9965254942207378 0.3189948863352008 1.0 0.3854521543217009 2 Q6P4Q7 1 +Cilium biogenesis/degradation 0.369968651858935 0.7134401454867606 0.4755734385834431 1.0 0.546330223114706 22 O95684,O75665,O95721,Q9Y5Y2,Q9Y366,Q96J42,Q15154 7 +Adaptive immunity 0.4033295598619936 0.7107260914644378 0.4772539880082489 1.0 0.546330223114706 17 Q07021,Q03519,P60033,P04439,P10321,Q9NZ08,Q03518 7 +Porphyrin biosynthesis 0.4535973721157825 0.6946412231911552 0.4872801712985524 1.0 0.5541617634375694 5 P22830 1 +Proline biosynthesis 0.4088252483927508 0.6063714371074463 0.5442681310083253 1.0 0.6032016229009465 3 Q96C36,P54886 2 +Chemotaxis 0.4098216895644626 0.5246257546592815 0.5998433793255793 1.0 0.6564323773751622 4 P26583,Q8NHP6,P09429 3 +Inflammatory response 0.3667515103277193 0.2170248078511749 0.8281890117815855 1.0 0.873362957878763 9 Q8IV08 1 +Angiogenesis 0.3488101527005305 0.1854449077464224 0.8528800879236023 1.0 0.893982742763294 13 Q9BUP3 1 +Oogenesis 0.3116959064327519 0.0246541155532174 0.9803308544277778 1.0 1.0 5 O60879,Q9Y5A9,Q15645,Q9H6S0 4 +Stress response 0.2527070714894904 0.0110890703037324 0.9911523833395536 1.0 1.0 31 Q9Y241,O95197 2 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..24339606bfd90d35872dc9c557bdf50c28a8a9cf --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine metabolism", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ABI2", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALG13", "ALKBH5", "AMFR", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMC10", "ARMT1", "ARRB2", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "AUP1", "AURKA", "BABAM1", "BAG3", "BAG6", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BET1", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "CABLES1", "CACYBP", "CAD", "CADM1", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP3", "CASP7", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC59", "CCDC86", "CCDC94", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CD81", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPV", "CEP55", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCC1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG7", "COL4A3BP", "COMMD10", "COMMD7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "COQ9", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRCP", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC2", "DSG2", "DST", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM210B", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXK2", "FOXRED1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGT7", "GHITM", "GID8", "GINS2", "GINS3", "GINS4", "GLTP", "GM2A", "GMPR2", "GMPS", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPI", "GPKOW", "GPR89B", "GRAMD4", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKG", "ILF2", "ILF3", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INTS3", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIF11", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LEO1", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMBRD1", "LPCAT1", "LPCAT4", "LPGAT1", "LRP1", "LRPPRC", "LRRC8A", "LRWD1", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGT1", "MANF", "MAP1S", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED16", "MED17", "MED23", "MED24", "MED25", "MED4", "MESD", "METTL3", "MFAP1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MICALL1", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMGT1", "MMS19", "MOB4", "MOCS3", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MRC2", "MRE11", "MRI1", "MRPS27", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MVK", "MYBBP1A", "MYCBP", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFCD", "NES", "NHP2", "NIP7", "NIPBL", "NKRF", "NLE1", "NLRX1", "NME1", "NME3", "NME4", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OFD1", "OGDH", "OGFR", "OGT", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "PA2G4", "PABPC1", "PABPN1", "PACS1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXIP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PECR", "PELP1", "PEPD", "PES1", "PEX11A", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHGDH", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "PPAT", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", 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"RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBM10", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RIF1", "RING1", "RINT1", "RIOX1", "RMDN3", "RMND1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAI", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDE2", "SDF4", "SDHA", "SDHB", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD1A", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC35F1", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORT1", "SPATA5", "SPC24", "SPC25", "SPECC1L", "SPEN", "SPIN1", "SPOUT1", "SPTLC1", "SPTLC2", "SRCAP", "SREK1", "SRM", "SRPK1", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNGR2", "TACC3", "TADA3", "TAF6L", "TAF9B", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TARSL2", "TBCB", "TCAF1", "TCEA1", "TCERG1", "TDP2", "TDRKH", "TECR", "TEFM", "TENM3", "TERF2IP", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TK1", "TLE3", "TLN1", "TM7SF2", "TM9SF1", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM14C", "TMEM214", "TMEM38B", "TMEM59", "TMX1", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TRMT61A", "TROVE2", "TSFM", "TSG101", "TSNAX", "TSR1", "TTC19", "TTC26", "TTC4", "TTF1", "TTF2", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC15", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAC2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGDH", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCR11", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URGCP", "UROD", "USO1", "USP10", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTI1B", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WDR12", "WDR33", "WDR36", "WDR41", "WDR43", "WDR5", "WDR6", "WDR61", "WDR75", "WTAP", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YIF1A", "YIF1B", "YIPF4", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "ZC3H11A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZMYND8", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAAS", "ABCB7", "ABCD3", "ACBD5", "ACOT8", "ACOX1", "ACP6", "ACSL6", "ADI1", "AGPAT5", "AGPS", "ALDH18A1", "ALDH3A2", "ANO6", "APOL2", "APOO", "APP", "ARFGAP2", "ARL6IP1", "ASAH1", "ASNA1", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP6V1E1", "ATP7B", "BAG6", "BCAP29", "BCAP31", "BCL2L13", "BET1", "BNIP1", "BUB1B", "C1QBP", "CAMLG", "CCDC51", "CD81", "CDIPT", "CDS2", "CERS1", "CERS2", "CETN2", "CHMP2A", "CHMP3", "CISD2", "CLCC1", "CLCN3", "CLPTM1L", "CNNM3", "CNNM4", "COQ8A", "COQ9", "COX2", "CPT1A", "CPT2", "CYB5B", "CYB5R3", "CYC1", "CYP51A1", "DAGLB", "DERL1", "DERL2", "DHCR24", "DIABLO", "DIAPH2", "DNAJC19", "DOHH", "EBP", "EI24", "ELMO2", "EMC4", "ERAP1", "ERC1", "ERG28", "ERGIC1", "ERGIC2", 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pval_hit pval_50 pval_100 pval_250 pval_500 +Primary mitochondrial disease 44 107 4.229345935736339 2.343717169028814e-05 27.53640776699029 92.44660194174756 0.9978626953080288 0.3665723479658412 11.863754653333944 10.66022291187525 1.7959996823414457 0.3879563837717744 6.826384504253662e-11 0.0001377367296412 6.022693851909288e-08 5.422393828511366e-10 3.136870119642571e-12 +Neuronal ceroid lipofuscinosis 4 5 2.6232484328487 0.008709573851191 2.1941747572815533 3.616504854368932 0.8145003765175237 0.1716854616439567 0.950812145720796 0.8293870806734848 1.6764073513361384 0.2241811956153294 0.0149736639257102 1.0 1.0 0.0328731354880699 0.0019884945269669 +Congenital disorder of glycosylation 8 21 2.314939765482518 0.0206162287347333 5.618932038834951 18.325242718446603 0.4013656328493284 0.4500757016048167 2.8520016519219875 3.440343696044481 1.1296344785223882 0.3186521023843959 0.0001536353746473 1.0 0.3530974878629287 0.0949405615621671 0.0002580266226921 +Ichthyosis 5 12 2.2555981963376435 0.0240958062834255 2.424757281553398 8.70873786407767 0.6701903086786922 0.3798909770564678 1.5631275250389387 1.4270688811262522 1.102920967881483 0.3152318826682235 0.0281915688746196 0.1178616319260966 0.2223047329091382 0.0242110622206542 0.0351238878380088 +Cataract 9 28 2.07274989624024 0.0381955615358735 7.509708737864078 26.679611650485437 0.6066406061606927 0.4718259290301406 3.570701015264242 3.2395121058789256 1.0572468917106954 0.3422408621391183 0.0009632698194349 1.0 1.0 0.4035011436345253 0.0015622461376846 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d5674fdc5c061541d1436cda29d541f6a8989e55 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 118, + "title": "Average number of proteins per term", + "value": 22.694915254237287 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..44837f5693cba1c7ed41761f46e4ada4ad9bf53a --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..04a6189c9d40b39d71fbe76fb7118698e0b03da8 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,39 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary mitochondrial disease 0.5649408537490114 4.229345935736339 2.343717169028814e-05 0.0027617978685138 0.0027655862594541 107 O14949,Q8N183,Q86Y39,Q9BQT8,Q9BRT2,Q96IX5,Q9NX14,Q9Y2R0,Q9Y584,Q9Y6M9,O43819,Q6DKK2,P13073,Q5XKP0,O43676,Q9Y276,Q9NWS8,P22695,Q9BUB7,Q96CU9,Q9P0J0,P00846,Q7KZN9,Q8NI60,P52815,P12235,O95169,P20674,O60313,Q70HW3,Q53H12,Q9HA77,P03886,Q96I36,P03915,P08574,Q9UBX3,P00403,O75880,Q6P4A7,P14927,Q9NPL8,Q8IUX1,Q9Y375 44 +MELAS syndrome 0.8621092608822731 3.191747468117705 0.001414149125211 0.1537899781234931 0.0104293497984318 2 P03886 1 +Gaucher disease 0.850131463628404 3.1341050233353753 0.0017237914766761 0.1841974382602173 0.011483430913578 2 P07602 1 +Leber hereditary optic neuropathy 0.8623611922852173 3.051333754073445 0.0022782717360301 0.2359658345079413 0.0129397040606044 3 P00846,P03886 2 +Ehlers-Danlos syndrome 0.8768284537142619 2.981250518814263 0.0028707384603603 0.2876844646431748 0.0147281364488052 4 Q9NWM8,Q8NCH0 2 +Zellweger syndrome 0.8082992402104097 2.790886998200691 0.0052563820181616 0.4630707570558555 0.0221518956479671 3 O75381,P40855 2 +Neuronal ceroid lipofuscinosis 0.821052631578961 2.6232484328487 0.008709573851191 0.6437887823370032 0.0321165535762671 5 Q9NQ11,Q9NWW5,P50897,O14773 4 +Peroxisome biogenesis disorder 0.7981631441380305 2.607190848096655 0.0091288463588072 0.6611340963334482 0.0326425415254321 4 O75381,P40855 2 +Congenital disorder of glycosylation 0.5957126337703886 2.314939765482518 0.0206162287347333 0.9144061437925064 0.0565747672255473 21 Q9BYC5,Q8N511,P46977,O75787,Q9BT22,P51571,Q96AA3,Q9H0U3 8 +Ichthyosis 0.7196112014575246 2.2555981963376435 0.0240958062834255 0.9437596848832096 0.0646205713964594 12 Q9Y2B2,O95721,P04062,Q15125,P51648 5 +Cataract 0.4948247501256989 2.0727498962402393 0.0381955615358735 0.9899018998562258 0.0958952396007038 28 Q15125,Q9UG56,Q9H6K4,P08670,Q53H12,Q8TC12,O76024,O00400,Q15800 9 +Hereditary spastic paraplegia 0.5621221970654328 1.7893081666798123 0.0735651995584136 0.9998786182111185 0.1607535842202372 17 O75298,O75477,O94905,Q9NQ11,O00400,Q15041 6 +Joubert syndrome 0.6460943381858817 1.7442795572689174 0.0811103545170046 0.9999537537834072 0.167912663736957 5 O43924,O75665 2 +Xeroderma pigmentosum 0.5626643295354999 1.6098522248174905 0.1074301208650356 0.9999985010650696 0.2078156436405608 2 P18074 1 +Cockayne syndrome 0.5626643295354999 1.6098522248174905 0.1074301208650356 0.9999985010650696 0.2078156436405608 2 P18074 1 +Diabetes mellitus 0.5980200116700096 1.5791925527345527 0.1142918976343063 0.9999993970339304 0.2175232890459379 12 Q8N5K1,Q9Y5U9,O76024,P03886 4 +Cardiomyopathy 0.4230922699143123 1.4549134407005495 0.1456932263643575 0.9999999914801044 0.2604818289544575 27 Q96DA6,O60313,P00846,Q53H12,P50402,O43819,P12235 7 +Leigh syndrome 0.5720559028775013 1.3663868355794575 0.1718175785288485 0.9999999997817928 0.2938329603826684 10 Q7KZN9,O43819,P00846 3 +Nemaline myopathy 0.4916739702015902 1.192022946924395 0.2332522477686733 0.9999999999999756 0.3770378799548419 2 P06753 1 +Retinitis pigmentosa 0.4566190925140048 1.1306097292912531 0.258219390680324 0.9999999999999996 0.4117552445983546 18 O75665,Q96S66,P00846,Q96HR9 4 +Dystonia 0.5380269730959691 1.1016177357683892 0.2706278944575446 1.0 0.4257878872798702 7 P11166,Q15043,P51572 3 +Congenital muscular dystrophy 0.5190585872510759 0.9973091028593324 0.3186144966147206 1.0 0.472845554122119 7 O60762,Q8NAT1,O43505,Q14118 4 +Gangliosidosis 0.4974056342666694 0.9349772857057608 0.3498000054225088 1.0 0.4984891724900206 5 P07602,P17900 2 +Dystroglycanopathy 0.5106802594808921 0.9333637028129604 0.3506322145480653 1.0 0.4984891724900206 6 Q8NAT1,O43505,Q14118 3 +Deafness 0.3174241657023423 0.880847480110791 0.3784003771038779 1.0 0.5253087588030306 52 Q9Y2B2,O00400,Q9NR28,Q16740,Q9NWM8,Q9UG56,O60313,O60443,O76024,Q8N5K1 10 +Ciliopathy 0.4477003904597673 0.869057193068127 0.3848158489839262 1.0 0.528003141629108 15 O75665,Q9Y366,Q96J42,Q2M1P5,O43924 5 +Allergen 0.4186386210926114 0.7564522158464864 0.4493781115566597 1.0 0.5898682686891684 2 Q9BPX6 1 +Amyloidosis 0.4481427960114295 0.7340807903292773 0.4628995004486005 1.0 0.5937189244884223 4 P03886 1 +Mucopolysaccharidosis 0.4453471941991104 0.7185606188460739 0.4724116852404998 1.0 0.5994040737460105 4 P54802 1 +Emery-Dreifuss muscular dystrophy 0.466686193219012 0.6964750408149191 0.4861313827574087 1.0 0.6043357855252364 6 Q9BTV4,P50402 2 +Congenital myasthenic syndrome 0.4246493034292079 0.6958200642969665 0.4865415222448936 1.0 0.6043357855252364 3 P53007 1 +Parkinsonism 0.3934205197789476 0.4719834575177742 0.6369385962945966 1.0 0.7441460827996277 14 O75787,Q9NQ11,P04062,Q96A57 4 +Limb-girdle muscular dystrophy 0.3867571591954781 0.3245254897067156 0.7455402275838785 1.0 0.8541140471349288 10 Q8NAT1 1 +Lissencephaly 0.3659977241803502 0.2746351610307115 0.7835965500545434 1.0 0.8890807010234243 13 Q6ZXV5,Q9Y320,Q8NAT1,Q14118 4 +Spinocerebellar ataxia 0.3582136315436669 0.1925466210880984 0.8473140526959149 1.0 0.952219602077314 11 O14773 1 +Alzheimer disease 0.3529875108173083 0.141638962965805 0.8873651891771606 1.0 0.9785896478776164 6 P03886 1 +Neurodegeneration 0.2525643826995793 0.1187416075096055 0.9054800716933448 1.0 0.9893208190723582 142 P04062,P27544,Q8TB36,Q96A57,P05067,O75787,O14773,O15269,P07196,Q10713,O75298,Q8N766,Q15043,Q14108,Q13510,Q9NWW5,P05023,O75477,Q96RL7,O60313,O94905,Q9NQ11,P03886,P61026,Q15041,Q9Y320,O75503,Q8IV08,O95140,P50897,O00400,Q9UBB4 32 +Epilepsy 0.2436740679474658 0.0494454776061786 0.9605642865727366 1.0 1.0 71 P27544,Q9Y5U9,Q3ZCQ8,Q96RL7,Q96S52,O14874,O75787,Q9H490,O14773,P16615,Q14108,P03886,Q13510,P05023 14 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..484de913fbd6a18da0caa5f8f7749b96db54de1f --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Aortic aneurysm", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pseudohermaphroditism", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCC1", "ABHD11", "ABHD12", "ABI2", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP9", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG6", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA7", "AP1B1", "AP1S1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APP", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARSA", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG13", "ATIC", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7B", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAS3", "BCKDHA", "BCKDHB", "BCKDK", "BCLAF1", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRB", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD3", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C12orf57", "C19orf70", "C1QBP", "CAD", "CADM1", "CALR", "CAMK2G", "CAMLG", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBX2", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNB1", "CCNB2", "CCT5", "CDC16", "CDC20", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CENPF", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLIC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COASY", "COG7", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COQ8B", "COQ9", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "COX6B1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DARS", "DARS2", "DBI", "DBN1", "DBT", "DCPS", "DCTN1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DSC2", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHMT1", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPB41L3", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM210B", "FAM3C", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTB", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "FUT8", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLM", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI3", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPAA1", "GPI", "GRB2", "GSDME", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GUF1", "GYG1", "GYS1", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HARS2", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIP1", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGXB4", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFT27", "IFT52", "IGBP1", "IGF2R", "IKBKG", "ILF3", "ILK", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INTS1", "IPO7", "IRF2BP2", "IRF2BPL", "IRS4", "ISCA2", "ITGA6", "ITGB1", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KIF11", "KIF1A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS3BP", "LGMN", "LIPA", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRP1", "LRPPRC", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARS", "MARS2", "MATR3", "MBD1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED17", "MED23", "MED25", "MESD", "MFN2", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOGS", "MORC2", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MVK", "MYH10", "MYH14", "MYH9", "MYLK", "MYO6", "NAA10", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPH", "NCKIPSD", "NCOR1", "NCSTN", "ND1", "ND5", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NHLRC2", "NHP2", "NIPBL", "NME1", "NNT", "NONO", "NOP56", "NPC1", "NPC2", "NPM1", "NR2F1", "NR3C1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCLN", "OFD1", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PACS1", "PAF1", "PAFAH1B1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDSS1", "PDSS2", "PEPD", "PEX11B", "PEX14", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POMGNT2", "POP1", "POR", "PPA2", "PPFIBP1", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTK2", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RAC1", "RAC3", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RDH11", "RDX", "REEP6", "REPS1", "RFC1", "RFC2", "RFT1", "RINT1", "RMND1", "RNASEH2A", "RNASET2", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "RTN2", "RXRB", "SAMHD1", "SARS", "SART1", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SDHA", "SDHB", "SEC23A", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SIGMAR1", "SIN3A", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A9", "SLC33A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC9A3R1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SNAP29", "SND1", "SNIP1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF2", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUFU", "SUZ12", "SYNE1", "SYNE2", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBC1D8B", "TBCD", "TBCE", "TBL2", "TCEA1", "TCOF1", "TDP2", "TECR", "TELO2", "TENM3", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TK1", "TKFC", "TKT", "TMCO1", "TMEM106B", "TMEM126B", "TMEM165", "TMEM199", "TMEM230", "TMEM38B", "TMEM43", "TMEM70", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAF2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TSFM", "TSG101", "TTC19", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNDC15", "TXNRD1", "TXNRD2", "TYMS", "U2AF1", "UBA1", "UBE2N", "UBE3A", "UBIAD1", "UBQLN4", "UBR1", "UBR5", "UBTF", "UFSP2", "UGDH", "UGP2", "UMPS", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP4", "USP8", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13A", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP2", "WDR1", "WDR11", "WDR34", "WDR36", "WDR5", "WDR73", "WFS1", "WNK1", "XIAP", "XPNPEP3", "XPO1", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24"], "leading_proteins": ["AGK", "ALDH3A2", "ALG1", "APP", "ARL6IP1", "ASAH1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP6", "ATP6AP2", "ATXN10", "B4GAT1", "BCAP31", "BCKDK", "BCS1L", "C19orf70", "CARS2", "CERS1", "CHST14", "CISD2", "CLCC1", "CLN5", "CLN6", "CLPP", "COA3", "COQ8A", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CYC1", "DAG1", "DIABLO", "DNAJC19", "DPM1", "EBP", "EMC1", "EMD", "ERCC2", "ERLIN1", "ERLIN2", "FKBP14", "FOXRED1", "FUT8", "GBA", "GDAP1", "GM2A", "GSDME", "IER3IP1", "IFT52", "KIF7", "MAGT1", "MFN2", "MICU1", "MRPL12", "MSMO1", "NAGLU", "ND1", "ND5", "NDUFA11", "NDUFA13", "NDUFAF1", "NDUFAF2", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFB9", "NEFL", "OFD1", "OPA1", "OPA3", "PDE6D", "PEX14", "PEX19", "PIGL", "PIGS", "PIGU", "PISD", "PLD3", "PMPCA", "POMGNT2", "PPT1", "PSAP", "RAB10", "RDH11", "REEP6", "RFT1", "RMND1", "RTN2", "SCARB2", "SCO1", "SCO2", "SFXN4", "SLC25A1", "SLC25A10", "SLC25A21", "SLC25A26", "SLC25A4", "SLC2A1", "SLC33A1", "SLC39A14", "SNAP29", "SPTLC1", "SSR4", "STT3A", "TIMM22", "TIMM50", "TIMMDC1", "TMEM126B", "TMEM199", "TMEM230", "TMEM43", "TMEM70", "TMTC3", "TMX2", "TPM3", "TPP1", "TTC19", "TXNDC15", "UQCC2", "UQCRB", "UQCRC2", "UQCRQ", "USMG5", "VIM", "VPS13A", "WFS1"]} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/idx2term.json b/protein_atlas_molecular_function/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ffc2e2b305f3b9df35f02b7ba8de121f8b577b68 --- /dev/null +++ b/protein_atlas_molecular_function/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Receptor", "1": "Translocase", "2": "Glycosyltransferase"} \ No newline at end of file diff --git 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sha256:9a11830d9e236e0e9f597610af9e0351a70f91489cdab218f256ce925c6bfc58 +size 95922 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5e04a3f242c79246dc2b6367b5af0b6a6e6ddce2 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 17 47 3.528330675869101 0.0004181893941166 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.2439692382900427 1.0 0.2196755626061812 0.4028997659297014 0.1007278796313612 +Translocase 13 28 2.400923613338516 0.016353749896818 8.031553398058252 23.23543689320388 0.8266305625937611 0.3429767730570308 3.903132239147793 3.2553774114037415 1.2917497354360188 0.3272657999875639 0.0014038203904898 1.0 0.4407605172427877 0.1774767594454888 2.4886949241689784e-05 +Glycosyltransferase 16 41 2.3324932891874224 0.0196747555454372 8.383495145631068 33.63106796116505 0.9005425082235603 0.4380439374186179 3.633517034002208 4.6602851932859135 0.9766631781348049 0.3531801259598526 0.018957233620157 1.0 0.68527292971009 0.0690027967951049 0.0296324683723188 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..babb29a2ee2f7014e616678bbd1a99178fe84187 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 98, + "title": "Average number of proteins per term", + "value": 40.41836734693877 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..68b45ae40b7eee4052a5f3407eccba1e69c7487b --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..49760b313521ed35f0647dc10c1ca5de9723a06a --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,22 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.6020284424787782 3.5283306758691015 0.0004181893941166 0.0401623584890432 0.0043423956344462 47 P30825,P24390,Q9Y5M8,P60033,Q99623,O15118,O15173,O75787,P35613,P11279,Q9NS69,Q14118,Q14108,Q14739,O00264,P55899,P78310 17 +Porin 0.874341440214516 2.9696915069270933 0.0029809894130057 0.2536594326444195 0.0149667377129054 4 P45880,P21796 2 +Monooxygenase 0.8436586791350223 2.962205724484205 0.0030544362679398 0.2590282931101802 0.0149667377129054 3 Q16850,Q6UW02 2 +Translocase 0.535572510685392 2.400923613338516 0.016353749896818 0.8012916192480626 0.0500833590590052 28 P98194,P35670,Q03519,Q9NQ11,P16615,P06576,P03886,Q9HD20,P03915,P08574,P05023,P00403,Q13423 13 +Glycosyltransferase 0.491019196402707 2.3324932891874224 0.0196747555454372 0.8573478696896106 0.0584280619228137 41 Q9Y673,P04062,Q8NBI6,Q2TAA5,O43505,Q4G148,Q8NAT1,Q96L58,Q9BYC5,P46977,O60762,Q13126,Q9BT22,Q68CQ7,Q10472,Q93063 16 +Host cell receptor for virus entry 0.577898593050219 1.8920989041358272 0.0584778043156808 0.9972748203392838 0.1382914381894376 17 P60033,O15118,P35613,P11279,Q14108,Q14118,P78310 7 +Acyltransferase 0.4335058323963117 1.7985262659609311 0.0720936501340991 0.9993462580154236 0.1535908198509069 41 Q96N66,Q9NUQ2,Q92604,Q9NXS2,Q643R3,P50416,Q86UL3,Q9UJ14,Q9BWD1,P11182,Q8NF37,O15269,P23786 13 +Muscle protein 0.6457959216722775 1.6571762515876254 0.0974838464262362 0.9999568889685454 0.1949676928524724 6 P60660,P67936,P09493 3 +Ion channel 0.5565021893688432 1.3377944462574458 0.180963452808379 0.9999999968105076 0.3111301469337043 12 Q96S66,Q9C0H2,Q96ER9,Q9UM00 4 +Chloride channel 0.5486752888359696 1.217995265158626 0.2232257720451422 0.9999999999822624 0.347240089847999 5 Q96S66,Q9C0H2 2 +Guanine-nucleotide releasing factor 0.4869052386291185 1.200604256100184 0.2299047493032615 0.9999999999923904 0.3520416473706192 16 Q9HD47,P80303,Q02818 3 +Phospholipase A2 inhibitor 0.4574934268186 0.98779035662902 0.3232553313501214 1.0 0.4461834151029845 2 P04083 1 +Carboxypeptidase 0.4198739586351638 0.4526335393221609 0.6508126436602537 1.0 0.7416237102174984 6 Q9HB40,P10619 2 +Rotamase 0.3358697167105143 0.4083942222233627 0.6829842745675421 1.0 0.7609248463432932 21 Q9NWM8,Q9Y680 2 +Chaperone 0.2771098210676139 0.407992128528681 0.6832794538592837 1.0 0.7609248463432932 107 Q8N183,P46379,Q96A33,Q9H2J4,Q9Y5J9,Q01105,O43819,Q9NVH1,Q9Y276,P27824,Q9Y5L4,Q99471,Q96KC8,O14657,O95433,Q9NUG6,Q9Y5J7,O15212,O75880,Q96DA6,Q9NPL8,Q99733,Q8IUX1,Q9Y375 24 +Serine protease 0.3869002540131139 0.3370154984439379 0.7361052167950011 1.0 0.7927286950100011 11 Q16740,O14773,Q9H300,Q2T9J0 4 +Cyclin 0.3530099357101128 0.3074714742488261 0.7584845323574649 1.0 0.8079509149025169 3 P14635,O95067 2 +Heparin-binding 0.3770788979930218 0.2585674547074485 0.7959689968223216 1.0 0.829840017963697 8 P30533,P05067 2 +Cytokine 0.35446576439964 0.2447308143616613 0.8066648670083527 1.0 0.8321384943875639 4 P14174 1 +Oxidoreductase 0.2574269262540495 0.0421986506461233 0.9663403382322198 1.0 0.9808211296897136 179 O00767,P21912,Q8NBM8,Q99735,Q15067,O76062,Q53GQ0,Q9NRG7,Q9BUP3,Q9BU89,Q6PK18,Q6UW02,P13073,O95881,P16435,Q9Y394,P00374,Q96CU9,P09601,Q9BV57,P51648,P00387,P30519,Q96LJ7,O95864,Q16850,Q14534,Q6NUM9,Q8TED1,O75845,Q6UX07,Q8NBQ5,Q8TC12,Q8NBX0,Q14739,Q6IAN0,Q15738,Q9UHG3,Q9BY49,Q6ZRP7,Q15392,P50336,Q8NBN7,Q15800 44 +Lyase 0.2512623885371315 0.0365889543133933 0.9708127508153288 1.0 0.9808211296897136 44 O95470,Q99735,Q9UG56,Q6Y1H2,Q9P035,A1L0T0,P22830 7 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..49b91b0b839d3203b8dbb3405a83667e4f29351e --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA replication inhibitor", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD13", "ABHD16A", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG5", "ALG6", "ALKBH5", "AMFR", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APEH", "APEX1", "APP", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BAZ2A", "BCKDHA", "BCKDHB", "BCKDK", "BCLAF1", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "CABLES1", "CAD", "CADM1", "CALD1", "CALR", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBR1", "CBX2", "CBX3", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD81", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CEP55", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ8A", "COQ8B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERP44", "ESD", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FNTB", "FOXK2", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL3", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPA1", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD3", "LEO1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMBRD1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LPGAT1", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LRWD1", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MATR3", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED17", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL16", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MGEA5", "MGME1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MVK", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCBP3", "NCL", "NCOA5", "NCOR1", "ND1", "ND5", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFCD", "NES", "NHP2", "NIFK", "NIP7", "NIPBL", "NIT2", "NKRF", "NLN", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2F1", "NR3C1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUSAP1", "NXF1", "NXN", "OAT", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDRG1", "PDSS1", "PDSS2", "PEBP1", "PECR", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHC2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR2H", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R8", "PPP3CA", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RHOT1", "RHOT2", "RIDA", "RING1", "RIOX1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "RXRB", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAI", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPIN1", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "SSU72", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUFU", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE1", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TM7SF2", "TMCO1", "TMEM109", "TMEM126B", "TMEM38B", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSN", "TSNAX", "TSTA3", "TTF1", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWNK", "TXNDC12", "TXNRD1", "TXNRD2", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBP1", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UST", "UTP3", "UTRN", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VPS4A", "VPS72", "VRK1", "VRK2", "WARS", "WARS2", "WASF2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WNK1", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "ZADH2", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZCRB1", "ZFR", "ZMPSTE24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF638", "ZNF687", "ZRANB2"], "leading_proteins": ["ACAT2", "ACOX1", "ADI1", "AGPAT5", "AHSA1", "ALDH3A2", "ALG1", "ALG11", "ALG5", "ANXA1", "APP", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5B", "ATP6AP2", "ATP7B", "B3GALT6", "B4GAT1", "BAG6", "BCS1L", "BSG", "CANX", "CCDC47", "CCDC51", "CCNB1", "CCNB2", 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overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 382 664 11.328639845037248 9.466330862652144e-30 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 3.728426252677749e-92 1.1441187315475326e-12 6.826816386100029e-27 5.954735782783962e-59 9.592847109626694e-97 +Transporters 175 417 6.590638058775561 4.379403407371568e-11 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 9.165947735456811e-32 0.1574693569600455 0.0073128340463263 9.717897194119356e-12 2.714874090211579e-35 +Predicted secreted proteins 20 58 2.9359342041002376 0.003325448487244 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.3352311926620985 0.1386157823902389 0.2591565884814332 0.4781264107059845 0.3271088547462072 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..348d601688f1d591a50d43a55ce7bf8656f55879 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 519.6666666666666 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..07afd268782a55322cd92a3d5f0c1a7bb8f66445 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2bf2a811c779fa50d092f67b13dab037e280f158 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,8 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.7171145129985301 11.328639845037248 9.466330862652143e-30 2.1000000000198798e-17 2.1000000000198798e-17 664 Q6IC98,Q86Y39,Q86YN1,Q8N4V1,Q8NC54,Q8WY22,Q96A26,Q96A33,Q96A57,Q96EX1,Q96G23,Q96J42,Q96ND0,Q99595,Q9BQE5,Q9NQC3,Q9NS69,Q9NX00,Q9P2W9,Q9UDW1,Q9Y2R0,Q9Y584,Q6UW02,P13073,O43676,O60637,O60830,O75298,O95197,O95249,O95873,P00846,P09601,O43169,Q4ZIN3,Q13505,P67812,P51648,P43307,P30519,Q5BJH7,Q9H4I3,O00461,Q9NZ45,Q3SXM5,Q9BUR5,Q969V3,Q9Y282,Q9Y5M8,Q9UDX5,P57105,Q16850,Q8N511,O60499,O15173,Q8NCH0,Q6NUK4,Q8WVI0,Q96H78,O00264,Q9NX40,Q96I36,O75844,O96005,O75964,O95167,P00403,Q8WVC6,Q96PC5,Q96CP7,Q9NUN5,P24539,Q86W74,Q9H6K4,Q07065,Q8N8Q8,Q8N5M9,O14681,P50402,Q9NPA0,Q96AG4,Q68CQ7,O14957,Q96HR9,Q15070,Q9BSR8,Q15005,Q70UQ0,Q9BSK2,Q9H1E5,Q86UE4,O43657,P27544,Q5BJH2,Q9Y241,O14925,O95070,Q9BXK5,Q8N2F6,Q9BUP3,Q9BT22,O60725,Q9H061,Q12981,Q6PK18,Q96KA5,Q9Y3A6,Q6PI78,Q96RQ1,Q8N9F7,O95470,Q5VW38,P24390,O43808,P49069,Q9H6V9,Q8IXM6,Q6Y1H2,Q5SNT2,P49755,Q9H3N1,Q9NX62,Q8TB61,Q10472,Q8NC44,Q96AQ8,Q96AA3,P12235,Q9H330,P56962,Q8NHH9,Q9C0H2,Q9NZJ7,Q9UKU0,Q08722,P60033,Q14534,Q00765,Q70HW3,Q9P0S9,Q5SGD2,Q9UJ14,Q96S66,O75027,O43292,P03886,Q9BXS4,P13473,Q8N6S5,Q9Y6C9,Q15041,Q9UBX3,O60831,Q9H6H4,Q9Y673,Q9Y320,Q15388,O94901,Q567V2,Q15125,Q8IV08,Q9H3K2,Q9NPL8,Q9UBV2,Q8IUX1,Q07820,Q15392,Q8N5K1,Q8NEW0,Q15800,Q9H0U3,O15260,Q05086,Q9GZP9,Q9NR28,P49257,Q7Z3D4,O75192,Q53GQ0,P50416,Q9GZY4,P35613,O43760,P16615,Q99640,O14548,O43819,O15269,Q9NTJ5,Q15363,P27824,Q96ER9,O94919,O95202,Q9P0J0,P46977,Q8WVQ1,P12236,O75071,Q7KZN9,Q86UL3,P11279,Q14108,Q14118,Q96GC9,A1L0T0,Q9NWW5,Q8TBA6,Q6NTF9,Q86Y07,Q8N8L6,Q96N66,P35670,Q03519,Q9BYC5,Q9UG56,Q9NQX7,Q6NUM9,O75845,Q13190,Q8IWA4,Q9P035,Q9HD20,Q8NF37,P55899,P51571,Q9UM00,O75880,Q6P4A7,Q9BUN8,Q9Y3D6,Q9UNL2,Q96S52,O75381,P30511,Q86VR2,Q6ZRP7,Q8IYS2,O00400,Q9UEU0,Q96JJ7,Q9Y2U8,P09493,O15400,O95168,Q8TBP6,Q92604,Q99735,Q9HC21,Q9Y5U9,P51790,Q14728,Q7Z7H5,O75787,P37268,Q969X5,Q9H300,O76024,P57088,Q92542,Q9Y639,Q9Y5Z9,O15127,P16435,Q2TAA5,Q6UW68,Q8TAA9,Q96SK2,Q9BUB7,Q9UBU6,Q3ZCQ8,O95139,Q8N766,Q9H490,P00387,P42892,Q96KC8,P05023,Q15629,Q13423,P30825,Q99805,Q8IZA0,Q6NXT4,O15258,P51572,Q9NR77,P05141,Q86XL3,O15155,O75396,Q9NQ11,Q14739,Q8NE01,P03915,Q6IAN0,P08574,O60476,P78310,Q13641,Q8NBM4,Q93050,O43752,Q9UNK0,O15118,O95140,P10321,Q96CS3,Q92643,Q5JRA6,Q6RW13,P98194,Q8NBU5,Q9UKV5,Q8NCG7,P11117,O00767,P28288,Q4KMQ2,Q8TB36,Q96M27,Q9UKR5,Q9Y3B3,P05067,Q5VV42,Q8IWB1,Q9NWR8,Q9Y2W6,Q9NX14,Q9Y276,Q5J8M3,Q5SWX8,Q5T8D3,Q92544,Q6NUQ4,P18031,Q15043,P36383,O15321,Q9BTX1,Q6ZXV5,O95864,O95169,Q9BRX8,O14735,Q8NBX0,Q02978,Q15738,Q52LJ0,Q9UBG0,Q9Y619,Q9Y2C2,Q9NUQ2,Q643R3,O95674,Q9Y3E0,Q9UHQ4,Q8N1S5,Q92896,Q12893,Q9HD45,Q96SY0,P27105,Q15904,Q9UH99,P05556,P08195,Q16799,Q96IX5,O76062,P56589,Q6UWP7,Q9P260,Q9HCU5,Q9NVH1,Q96KR6,Q9NWS8,Q9Y679,Q92575,Q12846,Q03518,Q8N2K0 382 +Transporters 0.5376868583462816 6.590638058775561 4.3794034073715674e-11 9.196747361452663e-10 3.0655824551600976e-10 417 P28288,Q4KMQ2,Q8N4V1,Q8WY22,Q96A33,Q96A57,Q9Y3B3,P05067,Q9NWR8,P13073,P53007,O60637,Q9Y276,Q9Y512,Q5J8M3,Q5T8D3,Q92544,Q9UJS0,P45880,Q15043,P36383,O15321,Q9BTX1,Q6ZXV5,Q9BUR5,Q969V3,P20674,Q8TEX9,O00560,P57105,Q8N511,O94905,Q96H78,Q02978,O75844,O96005,P00403,Q96PC5,Q9Y619,Q9NUN5,Q9UHQ4,Q07065,Q8N8Q8,Q8N1S5,O14681,Q9NPA0,Q96AG4,P27105,Q15904,Q15070,Q9UH99,Q9BSK2,O75746,Q92973,P05556,Q9BQT8,P08195,Q16799,P56589,Q7Z3B4,Q9NV70,Q9H061,Q5VW38,P24390,O43808,P49069,P07602,P49755,Q9H3N1,Q8TB61,Q96AA3,P12235,P56962,Q8NHH9,Q9C0H2,Q9NZJ7,Q08722,P60033,O60313,Q70HW3,Q96S66,O95433,O75027,Q9BXS4,P13473,Q9Y6C9,Q9UBX3,O60831,Q9Y320,O94901,Q9UBV2,Q9H2D1,Q8IUX1,Q8NEW0,Q9UBQ0,Q9H0U3,Q9Y371,O15260,P21912,P40855,Q9GZP9,P49257,O75192,P50416,P35613,P16615,Q16891,Q9BRK5,O43681,Q15363,O95202,P46977,P12236,P11279,Q14108,Q14118,Q96GC9,P52292,Q9NWW5,Q8TBA6,Q6NTF9,Q96N66,P35670,O75477,Q03519,Q96RL7,Q13190,Q8IWA4,Q9HD20,Q6NUK1,Q9UM00,Q6P4A7,Q9BUN8,O75381,Q15006,O00400,Q9UEU0,Q96JJ7,Q8TBP6,Q9HC21,O60443,O75787,Q9H300,O76024,P57088,Q9Y639,O15127,Q6UW68,Q8TAA9,Q9BUB7,Q9UBU6,Q9NQZ5,Q8N766,P05023,Q15629,P30825,Q99805,Q6NXT4,O15258,P51572,Q9NR77,P05141,P49458,Q9NQ11,Q8IYU8,Q8NFH5,Q8NE01,P78310,Q93050,O43752,O96008,O15118,O95140,Q5JRA6,P98194 175 +Predicted secreted proteins 0.477917674159667 2.9359342041002376 0.003325448487244 0.067560297431625 0.009976345461732 58 Q8N128,Q8NBM8,Q9NZ08,P05067,Q02818,P14174,Q99584,O94919,Q9Y4P3,Q9HB40,P80303,P84157,Q9BUR5,Q9BRX8,Q8WUY1,Q6UX07,P78310,Q92520,Q9UM22,Q15165 20 +CD markers 0.5136526219247666 1.7374491709861355 0.0823079184723998 0.8353215877946325 0.1728466287920396 21 Q9UBG0,Q08722,P05556,P60033,P35613,P11279,P13473 7 +Potential drug targets 0.2516626818814449 0.2273633073830221 0.8201412496261795 0.9999999999999998 1.0 523 P04062,P28288,Q4KMQ2,Q96A33,Q5VV42,P14174,P13073,P53007,Q9Y276,Q5T8D3,Q9UJS0,P09601,P49915,Q15043,P51648,P11182,Q9HCC0,Q6ZXV5,P20674,Q8N511,O94905,Q8NCH0,Q9HA77,Q9NRA0,Q13126,Q02978,O75844,P10619,Q15738,P00403,Q96PC5,Q9NUN5,Q9NWM8,Q96D53,P50897,O14681,Q9Y2B2,Q9BQT8,O14773,Q9BT22,Q9H061,O95470,P22695,P07602,Q9NX62,P22830,Q96AA3,Q9UKU0,P60033,O60313,Q70HW3,Q96S66,O75027,P13473,Q9Y320,Q8NAT1,Q15125,Q8IV08,Q9H2D1,Q8IUX1,Q15392,Q15800,Q9H0U3,P21912,P40855,Q05086,Q16740,P49257,O15269,P46977,Q8WVQ1,Q14108,Q14118,Q13510,Q9NWW5,Q8TBA6,Q96N66,P35670,O75477,Q03519,Q96RL7,Q9BYC5,O75845,Q53H12,Q8TC12,Q6NUK1,Q9UM00,Q6P4A7,Q96L58,O75381,O00400,Q9HC21,O60443,O75787,P37268,O76024,Q10713,P16435,Q2TAA5,Q8TAA9,Q9BUB7,O14874,Q8N766,O60566,P00387,P42892,P51572,P53701,Q9NQ11,Q14739,P03915,P08574,O15118,O95140,Q92643,Q7L592,O00116,P11117 118 +Human disease related genes 0.2369399796730827 0.1651468483210701 0.8688283995916453 1.0 1.0 976 O14949,Q8N183,Q86Y39,P04062,P28288,Q4KMQ2,Q8TB36,Q9BRT2,Q9Y366,P05067,Q96RT7,Q5VV42,Q9BQE5,Q8WWY3,Q9NX14,Q9Y584,Q9Y6M9,Q5XKP0,O43676,O75298,P00374,P00813,P00846,P09601,P51648,P21964,Q8N511,Q8NCH0,O43924,Q96I36,O75844,P00403,Q9NUN5,Q9NWM8,Q9H6K4,Q96D53,P50897,P50402,Q96HR9,Q9Y2B2,P27544,Q9BQT8,O96000,O14773,Q9BT22,Q9H061,Q9UHX1,O95470,P22695,Q15907,P07602,Q9NX62,P22830,Q96AA3,P12235,O00165,P60033,O60313,Q70HW3,O75027,O43292,P03886,P13473,Q15041,Q9UBX3,Q9Y320,Q8NAT1,Q15125,Q8IV08,Q9H7Z7,Q96DA6,Q9NPL8,Q8IUX1,Q15392,Q8N5K1,Q15800,Q9H0U3,P21912,P40855,Q05086,Q9NR28,Q16740,P49257,P08670,P50416,P16615,O43819,O15269,P23786,Q9NVI7,O95202,Q96CU9,Q9P0J0,P46977,Q9Y4P3,Q8WVQ1,Q7KZN9,Q14108,Q14118,Q13510,Q9NWW5,Q96N66,P35670,O75477,Q03519,Q96RL7,Q9BYC5,O75845,Q53H12,Q8TC12,P51571,Q6NUK1,Q9UM00,O75880,Q6P4A7,Q96L58,Q96S52,O75381,O00400,Q96JJ3,Q9Y2U8,P09493,Q96HY6,O75665,Q9HC21,Q9Y5U9,O60443,O75787,Q969X5,O76024,Q01105,Q92542,Q6DKK2,Q9Y5Z9,P07196,Q10713,O95721,P16435,Q2TAA5,Q8TAA9,Q9BUB7,Q3ZCQ8,Q9NQZ5,O14874,Q8N766,Q9H490,P49770,O60566,P00387,P42892,P05023,Q13423,P51572,Q9NR77,P53701,Q86XL3,Q9NQ11,Q14739,P03915,P08574,P14927,O15118,O95140,P10321,Q92643,O00116,P98194,Q8NBU5,Q9Y375,P11117 170 +Candidate cardiovascular disease genes 0.3399896366583889 0.1026144031694253 0.9182690111110304 1.0 1.0 10 Q15165 1 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4ea5b67c95eb1b36fb52086d2b2023132ccc9b5c --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD13", "ABHD16A", "ABHD6", "ABI2", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG13", "ALG5", "ALG6", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD46", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf50", "C2orf49", "C5orf15", "C5orf22", "C5orf24", "C6orf47", "C8orf33", "CAB39", "CABLES1", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC59", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CD81", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPH", "CENPI", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMC2", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "CNTLN", "COA1", "COA3", "COA7", "COASY", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1C", "CORO7", "COTL1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRCP", "CRK", "CRKL", "CRMP1", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "ENPP4", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM210A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTB", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GJC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI3", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPX8", "GRAMD4", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IBTK", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPA1", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS4", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1211", "KIAA1468", "KIAA1671", "KIAA2013", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED17", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL16", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS12", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS21", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYLK", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NENF", "NES", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OFD1", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACS1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX11A", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTMA", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABL6", "RAC1", "RAC3", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETREG2", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAI", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A6", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC35F1", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMIM8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX30", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUFU", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THEM6", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM128", "TMEM14C", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF1", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", 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"VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC2HC1A", "ZC3H11A", "ZC3H14", "ZC3H15", 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--- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondria 134 451 5.062084772328257 4.146965433527259e-07 110.1747572815534 400.5485436893204 0.4320244196044261 0.5794127039570083 42.49664228528663 36.15232166758906 2.0400795827803786 0.4211568684384254 2.4239777453522158e-26 1.4894604377188729e-06 2.743869154549137e-13 2.078836046794145e-18 1.3369494201204069e-27 +Endoplasmic reticulum 92 211 4.897032205446211 9.72948973895383e-07 55.37621359223301 196.57766990291265 1.2201083743235763 0.4903523338807414 18.868778270733547 13.264167600850914 1.8573715045605257 0.4308007257692164 1.3010963095575629e-25 4.848689567494516e-06 1.854745762289293e-07 1.0334294882859303e-16 7.886146263946916e-24 +Golgi apparatus 73 201 3.666818679822825 0.0002455868057011 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 2.6778146308238985e-05 0.0123623370114379 0.0505255554540771 0.0049188799931896 2.3609851621979856e-05 +Nuclear membrane 23 69 3.127052177659007 0.0017656858762697 16.817961165048544 62.713592233009706 0.5402747034161678 0.5293388535672136 7.339768502370818 5.865441797870943 1.2287110387783358 0.3803813474041967 0.0036870907377104 0.2177059049323894 0.5250511846313772 0.0329605406234942 0.0013321033486234 +Lipid droplets 5 10 2.148878985069705 0.0316439940819919 3.0072815533980584 9.62621359223301 0.341030817631545 0.5500740955075814 1.9327141206562328 1.0125869172856077 0.8582489651663355 0.3093604356540435 0.0925472416972236 1.0 0.2070995190727305 0.4452488918515388 0.0269295467729808 +Peroxisomes 8 16 1.9749876417911856 0.048269550470904 5.322815533980583 14.701456310679612 0.4359129333192138 0.4564689114892047 2.679509416580786 1.5010345350043446 1.0794334084892987 0.3191667601086948 0.0134770599498747 1.0 1.0 0.4028006685093745 0.017002584405276 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5e2b62f328c7eebf73049047862f00887ba1763f --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 157.66666666666666 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7a0b04f3203803dbe722627c6718a314a4405a1b --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C388/C388_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..960f363b221aa6523715c84896211bb35921413a --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondria 0.451144222214174 5.062084772328257 4.146965433527259e-07 1.3684895129200276e-05 1.3684985930672952e-05 451 O14949,Q8N183,Q86Y39,Q8N4H5,Q8NBM8,Q8TB36,Q8WY22,Q96A26,Q9BRT2,Q96EX1,Q96ND0,Q99595,Q9NWR8,Q9NS69,Q9Y2C4,Q9NX14,Q9Y2R0,Q9Y6M9,Q9NUJ1,Q69YU5,P13073,Q5XKP0,P52789,O60830,Q9Y512,P00374,Q9UJS0,Q9Y5L4,P45880,Q13505,P11182,Q9HCC0,Q9H4I3,Q9Y277,Q9NZ45,Q3SXM5,Q9BUR5,Q9UDX5,P57105,Q7Z7H8,Q8WVI0,Q96H78,Q9Y5J7,Q9NX40,Q96I36,O75964,P24539,O75431,Q96D53,Q68CQ7,Q15070,Q9NW81,Q9Y241,O14925,Q99623,Q7LGA3,Q9BXK5,Q9NRP2,Q8N2F6,P22695,Q9Y394,Q6UXV4,P12235,O00165,O60313,Q70HW3,O75027,O43292,Q9Y6C9,Q9UBX3,Q15388,Q9H3K2,Q9H7Z7,Q9BW91,Q9NPL8,Q9H2D1,Q8IUX1,P06576,Q07820,Q8NBN7,P21912,Q9NR28,Q16740,Q8NCN5,P56385,P50416,Q9GZY4,Q16891,O14548,O43819,P23786,O95302,Q96ER9,Q9NVI7,O95202,Q5HYI7,Q96CU9,Q9P0J0,P12236,Q7KZN9,Q53H12,Q8IWA4,Q6NUK1,Q6P4A7,Q9Y3D6,Q8WWC4,O43615,O95168,Q68D91,Q9HC21,Q9H300,Q9NQE9,Q6DKK2,Q10713,Q9BUB7,Q3ZCQ8,Q9NQZ5,O95139,O14874,Q8TAE8,Q13423,Q7Z4V5,P05141,P53701,Q5T9A4,Q8IYU8,Q9NQ50,P08574,Q9NX63,P35232,O96008,O95140,Q8NBU5,Q9Y375 134 +Endoplasmic reticulum 0.5571646395241765 4.897032205446211 9.72948973895383e-07 3.210681632312103e-05 1.6053658069290318e-05 211 O00767,Q96A33,Q96A57,Q96G23,O43852,Q9NQC3,Q9P2W9,P62820,O95197,O43169,Q4ZIN3,Q6NUQ4,P18031,Q15043,P51648,P84157,P43307,P21964,Q16850,O94905,O00264,O96005,Q15738,Q96PC5,Q9H0U4,O95674,O14681,P50402,Q96AG4,Q96HR9,Q70UQ0,Q86UE4,P27544,P05556,Q16799,O76062,Q6UWP7,Q14257,Q8WUJ1,Q9BT22,Q12981,Q96KA5,Q9HCU5,O95470,Q9NR31,Q92575,Q03518,Q9H3N1,Q96CN7,Q8NHH9,Q8NHP6,Q00765,Q96S66,P30533,O75915,O43292,Q15041,O60831,Q9H6H4,Q15125,Q8IV08,Q9Y680,Q8N5K1,Q15800,O15260,Q9GZP9,P49257,O15269,P27824,Q92791,Q96GC9,Q9NWW5,Q86Y07,O75477,Q03519,O75845,Q9P035,Q8NF37,P51571,Q9UM00,Q9BUN8,Q96HY6,Q99735,Q9Y5U9,P37268,Q6UW68,P00387,Q96KC8,P51572,Q86XL3,Q96CS3,Q9UKV5 92 +Golgi apparatus 0.4721797629309228 3.666818679822825 0.0002455868057011 0.0080726000538459 0.0016208729176278 201 O15260,Q8N6H7,Q8NC54,O95070,Q9NXU5,Q9NW68,Q96J42,Q96ND0,P05067,Q02818,O43760,Q99640,Q9BRK5,Q6IAA8,O95302,Q96RQ1,Q9NTJ5,O15127,O60637,Q5VW38,P24390,Q9UBU6,P09601,Q8WVQ1,P55327,Q9HB40,Q6NUQ4,P49755,P80303,Q15043,P67812,Q9BV57,Q9NX62,O75071,O15321,P20340,A1L0T0,Q5BJH7,Q8TBA6,O00461,Q6NTF9,Q8IZA0,P35670,Q6NXT4,O15258,Q9BYC5,Q9UG56,O60499,Q8NCH0,Q13190,Q9H4A6,O15212,O60476,Q93050,Q92520,P98194,Q9NXS2,O43752,Q9H0U4,Q9NWM8,P50897,Q9UKV5,Q92896,Q12893,O14681,O00231,A4D1U4,Q6ZRP7,Q8IYS2,Q6RW13,Q8NEW0,Q9UEU0,Q9BSR8 73 +Nuclear membrane 0.496108105509004 3.127052177659007 0.0017656858762697 0.0566511569184905 0.0083239477024147 69 O15260,Q9H1E5,O95168,Q14728,Q96G23,Q6UW68,Q96SK2,O94919,Q8IXM6,Q5SNT2,P67812,Q9BTX1,O00560,O14735,Q14739,Q8NFH5,Q8N6S5,O94901,Q9BW91,Q86VR2,P50402,Q96SY0,Q9Y2U8 23 +Lipid droplets 0.7149411189896685 2.148878985069705 0.0316439940819919 0.6539358069583565 0.0870209837254777 10 Q969V3,Q01105,Q96CS3,Q8NBQ5,Q8NF37 5 +Peroxisomes 0.606922860512913 1.9749876417911856 0.048269550470904 0.8045836840521496 0.1137782261099882 16 P40855,P28288,O43808,Q15067,Q5T8D3,Q9BY49,O75381,O00116 8 +Vesicles 0.2809280453525791 0.8458996271105889 0.3976087405510999 0.9999999455502566 0.5467120182577624 326 Q86YN1,Q8N128,Q96M27,P49257,P51790,O95070,P05067,Q8IWB1,Q969X5,P35613,Q9NWR8,O43399,Q6IAA8,Q9Y5Z9,O95302,Q96RQ1,Q15363,O15127,P16435,P52789,P24390,Q96SK2,P49069,Q96ED9,Q15907,P07602,Q92791,Q14118,Q8TB61,A1L0T0,P30519,P21964,Q5BJH7,Q96AA3,Q9NWW5,Q92783,P35269,Q3SXM5,Q08722,Q14534,O60499,P17900,Q53H12,Q9UJ14,Q6UX07,Q9H4A6,Q9NRV9,Q9NR50,Q8NBX0,Q9HD20,P13473,Q6UX53,P10619,Q52LJ0,Q8NBJ7,O60831,Q93050,Q6P4A7,Q9NUN5,Q8IXH7,Q9BPZ3,Q9UMR5,Q9UNK0,O15118,P50897,Q9Y3E0,Q9NRY5,Q8N5M9,Q9HD45,Q5JRA6,Q6RW13,P27105,O00400,Q9UBQ0,Q9UEU0,Q9BSR8 76 +Centriolar satellite 0.3373041370564866 0.705916534994731 0.4802400441348871 0.999999999581695 0.633916858258051 28 P41208,O43169 2 +Intermediate filaments 0.3289432956262601 0.6488985230251907 0.5164039694642866 0.9999999999612804 0.6554358073969792 31 Q3SXM5,Q86YN1,Q16352,P08670 4 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8b95d8e711b405939a5714a1e03aed4d55cc2986 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD13", "ABHD6", "ABI2", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALG6", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD46", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL15", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARRB2", "ARSA", "ARVCF", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BABAM1", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHB", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2orf49", "C5orf15", "C5orf22", "C5orf24", "C6orf47", "C8orf33", "CAB39", "CABLES1", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC59", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CD81", "CDC123", "CDC20", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPH", "CENPI", "CENPV", "CEP170", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN6", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMC2", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "CNTLN", "COA1", "COA3", "COA7", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COQ8B", "COQ9", "COTL1", "COX14", "COX15", "COX4I1", "COX5B", "COX6B1", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRCP", "CRK", "CRKL", "CRMP1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSCR3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELP1", "ELP2", "ELP3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM210A", "FAM210B", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTB", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FUT8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGT7", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GJC1", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPR2", "GMPS", "GNA13", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC2", "HEXA", "HGH1", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "IBA57", "IBTK", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFIT5", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS4", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP2", "IRF2BPL", "IRGQ", "ISCU", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1211", "KIAA1468", "KIAA1671", "KIAA2013", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "LZTFL1", "MACF1", "MAGED2", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED16", "MED17", "MED23", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS21", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYG1", "MYH10", "MYH14", "MYH9", "MYLK", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NELFCD", "NES", "NFATC2IP", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NME1", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSRP1", "NSUN2", "NSUN5", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OFD1", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACS1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGL", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PLXNA1", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPFIBP1", "PPIB", "PPID", "PPIE", "PPIF", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTK2", "PTMA", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB11B", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB6B", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETREG2", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOT2", "RIF1", "RING1", "RINT1", "RIOX1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAI", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A6", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F1", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMIM8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX2", "SNX27", "SNX30", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUDS3", "SUFU", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDP2", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM165", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM70", "TMEM97", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF1", "TTF2", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TXLNA", "TXLNG", "TXNDC15", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TXNRD2", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBLCP1", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP14", "USP15", "USP22", "USP24", "USP28", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VMP1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR77", "WDR82", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC2HC1A", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM4", "ZMYND8", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB7", "ABCD3", "ABHD10", "ACBD5", "ACOX1", "ADI1", "AGK", "AGPS", "AGTRAP", "ALDH3A2", "ALG1", "AMFR", "ANKLE2", "APOO", "APOOL", "APP", "ARFGAP2", "ARL15", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARMC10", "ATAD1", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP2C1", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6V0A1", "ATP7B", "BCAP31", "BCKDK", "BCL2L13", "BNIP1", "BRI3BP", "BSDC1", "BSG", "C12orf73", "C19orf70", "C5orf15", "CALU", "CAMLG", "CANT1", "CANX", "CCDC47", "CCDC51", "CD47", "CDIPT", "CDS2", "CERS1", "CERS2", "CETN2", "CHCHD3", "CHST14", "CISD1", "CISD2", "CLCC1", "CLCN3", "CLN6", "CLPP", "CLPTM1", "CLPTM1L", "CMC2", "COA1", "COA3", "COMT", "COQ8B", "COX14", "COX15", "COX4I1", "COX7A2L", "CPT1A", "CPT2", "CTSA", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP51A1", "DAG1", "DBT", "DDRGK1", "DERL1", "DERL2", "DHFR", "DHRS13", "DHRS7", "DIABLO", "DMAC2", "DNAJC1", "DOLPP1", "EBP", "EFCAB14", "EI24", "EIF2B3", "EMD", "ENDOD1", "ERGIC1", "ERGIC2", "ERLIN1", "ERLIN2", "EXOG", "FAF2", "FAM114A2", "FAM162A", "FAM177A1", "FAM210A", "FAM3C", "FAM8A1", "FAM98B", "FDFT1", "FIS1", "FKBP14", "FKBP7", "FKBP9", "FOXRED1", "FUT8", "GADD45GIP1", "GDAP1", "GGT7", "GHITM", "GLG1", "GLT8D1", "GM2A", "GOLGA5", "GOLIM4", "GOLPH3", "GOLT1B", "GPAA1", "GPR107", "GTF2F1", "HACD3", "HAX1", "HCCS", "HDGFL2", "HEBP1", "HIGD1A", "HINT3", "HK2", "HMOX1", "HMOX2", "HOOK2", "HS2ST1", "HSD17B11", "HSDL1", "IER3IP1", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "INA", "INTS14", "ISOC1", "ITGB1", "ITPRIP", "JAGN1", "KDELR1", "KIAA0319L", "KIAA1147", "KIAA2013", "LAMP2", "LAMTOR1", "LBR", "LCLAT1", "LEMD3", "LETM1", "LMAN1", "LMBRD1", "LPCAT1", "LRPAP1", "LRRC59", "MAIP1", "MAN1A2", "MBLAC2", "MCCC2", "MCL1", "MCUB", "METTL7B", "MFN1", "MFN2", "MFSD10", "MGST2", "MIA2", "MIA3", "MICU2", "MOSPD2", "MRPL10", "MRPL40", "MSMO1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MTX2", "MTX3", "MXRA7", "NCLN", "NDC1", "NDUFA11", "NDUFA13", "NDUFAF1", "NDUFAF2", "NDUFB11", "NDUFB4", "NDUFB6", "NDUFB9", "NELFCD", "NNT", "NPC1", "NRM", "NSDHL", "NUCB1", "NUCB2", "NUDT9", "NUP35", "OCIAD1", "OPA1", "OXA1L", "P3H4", "PAIP2", "PARL", "PCYOX1L", "PDPR", "PECR", "PEX14", "PEX19", "PFDN6", "PGRMC1", "PHB", "PHB2", "PISD", "PKMYT1", "PLD3", "PMPCA", "POR", "PPT1", "PPT2", "PRAF2", "PREB", "PRRC1", "PSAP", "PSMD11", "PTGES2", "PTPN1", "QPCTL", "QSOX2", "RAB11B", "RAB1A", "RAB1B", "RAB6A", "RCN2", "RDH13", "REEP4", "REEP5", "REEP6", "RER1", "RETREG3", "RFT1", "RHBDD2", "RTN1", "RTN3", "RTN4", "SACM1L", "SAMM50", "SAR1A", "SC5D", "SCAMP2", "SCCPDH", "SCD", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SET", "SFXN4", "SGPL1", "SLC25A10", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC30A6", "SLC30A7", "SLC33A1", "SLC35B2", "SLC39A14", "SMIM12", "SMIM4", "SPTLC1", "SQLE", "SSR1", "SSR4", "STAM", "STARD7", "STOM", "STX10", "STX18", "STX5", "STX6", "STX8", "SUMF2", "SUN1", "SURF4", "SYNGR2", "SYNJ2BP", "TAP1", "TAP2", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM9", "TIMMDC1", "TM7SF2", "TM9SF1", "TM9SF3", "TMCO1", "TMED10", "TMED2", "TMEM115", "TMEM126B", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM70", "TMX1", "TMX4", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TPD52", "TPD52L2", "TRABD", "TSPAN3", "TTC19", "TXNDC15", "UBIAD1", "UBXN4", "UQCC2", "UQCRC2", "UQCRQ", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS29", "VRK2", "VTI1B", "YIF1A", "YIF1B", "YIPF4"]} \ No newline at end of file