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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:b4aeec0bfec3a9166fb9950d7f63c14d0cbd2c6bb079f7bacff1b2a8ec46c146
+size 69071

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3120,
+    "annotations_size": 54,
+    "title": "Average number of proteins per term",
+    "value": 2.574074074074074
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C392/C392_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,7 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.759445916876907	1.5871766159421332	0.1124726493406191	0.9984084721067484	0.4562031909791076	4	P21281	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.8537054860442688	1.57051189001626	0.1162960704419389	0.9987394314919458	0.4562031909791076	3	Q9HB40,Q9H3G5	2
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.6569115623427266	1.4481088627549474	0.1475866072965339	0.9998200655652084	0.4562031909791076	6	Q16763,P61088	2
+Histidine acid phosphatase active site [IPR033379]	0.9769082745349614	1.375539834709154	0.1689641448070769	0.9999543472290452	0.4562031909791076	2	Q9NPH0	1
+Tyrosine-protein kinase, active site [IPR008266]	0.4728905999358486	0.2496295589088869	0.8028738374114717	1.0	0.9445656608802748	3	P41240,Q15375	2
+Ubiquitin-activating enzyme E1, Cys active site [IPR033127]	0.4716073147257019	0.2466246712066103	0.8051987093531634	1.0	0.9445656608802748	3	Q8TBC4,Q9UBT2	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK16", "CDK2", "CDK4", "CDK5", "CDK7", "CDK9", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK1E", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SLK", "SND1", "SRPK1", "STK38", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACP6", "ATP6V1B2", "CPVL", "CSK", "EPHA7", "SCPEP1", "UBA2", "UBA3", "UBE2N", "UBE2S"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:4eb470bb3984b48d2f0451fcf6f6fbacdeb8e6135a973d8e79fc3ef754fba247
+size 69631

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3120,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.645161290322581
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C392/C392_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.6756508427516557	1.382328380466463	0.1668708956357365	0.9965159731360882	0.9044657062415662	5	O43847,Q10713	2
+EF-Hand 1, calcium-binding site [IPR018247]	0.4638652626403854	0.168445800943992	0.8662325788864669	1.0	1.0	35	P80303,Q02818,Q96D71,Q14257	4

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK16", "CDK2", "CDK4", "CDK5", "CDK7", "CDK9", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK1E", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "IQGAP3", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK38", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["NRDC", "NUCB1", "NUCB2", "PMPCA", "RCN2", "REPS1"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:dacd37dc20aa78a409ff59061be9c44a32789248986e04770e995d59e2ad1a91
+size 74037

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	5	8	2.189368810383685	0.0285700447014818	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.0261790509072994	1.2225095413484733e-05	1.5472815952013036e-06	3.2601061429064485e-08	5.838563656468111e-08

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3120,
+    "annotations_size": 274,
+    "title": "Average number of proteins per term",
+    "value": 2.6605839416058394
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C392/C392_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.8364154538910182	2.1893688103836855	0.0285700447014818	0.999644574455978	0.6431188821399696	8	P28070,P28072,P49721,P20618,P28074	5
+Annexin repeat, conserved site [IPR018252]	0.7402726871822586	1.795863873132922	0.0725161692978537	0.9999999988986152	0.6431188821399696	7	P09525,P07355,P04083	3
+14-3-3 protein, conserved site [IPR023409]	0.6913937058445689	1.6029130993335974	0.1089538412185406	0.9999999999999812	0.6431188821399696	6	P62258,P27348,P31946,P63104,P61981	5
+Oxysterol-binding protein, conserved site [IPR018494]	0.7167830351661908	1.412259554948808	0.1578735505522259	1.0	0.7209558808551652	4	Q9BXB4,Q9BZF1	2
+Syntaxin/epimorphin, conserved site [IPR006012]	0.6491890401016869	1.3886902189095058	0.1649269697369715	1.0	0.7370081434393275	7	Q9P2W9,O15400,O60499	3
+Heat shock protein 70, conserved site [IPR018181]	0.6402187109547307	1.2780979848235194	0.2012148794087203	1.0	0.7843592777590734	10	Q0VDF9,P48723,P11142	3
+Tetraspanin, conserved site [IPR018503]	0.9474021808851876	1.2678904114171634	0.2048370887778454	1.0	0.7843592777590734	2	O60637	1
+Intermediate filament protein, conserved site [IPR018039]	0.6033627417443349	1.1568586655992992	0.247330108689507	1.0	0.7880052300107548	8	P20700,P07196,Q03252	3
+Heat shock protein Hsp90, conserved site [IPR019805]	0.7054860442733384	1.0076360976717775	0.3136291928636865	1.0	0.8413473262510319	3	P07900,P08238	2
+Ubiquitin interacting motif [IPR003903]	0.5875345535494322	1.0021463807184188	0.316272900014074	1.0	0.8413473262510319	5	Q8IZ07	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.5441952304626884	0.9384827352446202	0.3479963853492287	1.0	0.8520549920704464	6	P49736,Q14566	2
+Haem oxygenase conserved site [IPR018207]	0.8280949326491581	0.8428653979280023	0.3993037274977302	1.0	0.8774295702430187	2	P30519	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.6380582263638359	0.7591164928393275	0.4477828739718292	1.0	0.910816556477837	3	P26583	1
+Cullin, conserved site [IPR016157]	0.5213099241386415	0.7235628610280036	0.4693341489268343	1.0	0.9386682978536688	5	Q13620,Q13616	2
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.7799871712636355	0.681675975859388	0.4954438617405663	1.0	0.9496169646125284	2	P10644	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7787042976266826	0.677506579945616	0.4980845966826472	1.0	0.9496169646125284	2	P01889	1
+DnaJ domain, conserved site [IPR018253]	0.4895965540634195	0.5885155148104037	0.556186323166185	1.0	0.9890312031093408	11	Q8WXX5,Q96EY1,Q99543,Q5F1R6	4
+Vinculin, conserved site [IPR000633]	0.7049390635022423	0.453044268026427	0.650516865411181	1.0	0.9899154314392202	2	P18206	1
+Polyprenyl synthetase, conserved site [IPR033749]	0.693072482360513	0.4203029304419289	0.6742641694115936	1.0	0.9899154314392202	2	O95749	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.5333289428527733	0.411143726529237	0.6809671485754862	1.0	0.9899154314392202	3	Q08426	1
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.6783194355355974	0.3811551504448614	0.7030881263749369	1.0	0.9899154314392202	2	P29692	1
+Histidine triad, conserved site [IPR019808]	0.5910840282232144	0.1907163782156707	0.8487478062556857	1.0	0.9955408173624316	2	Q9BX68	1
+Cadherin conserved site [IPR020894]	0.5779345734445098	0.1687364335017501	0.86600395986813	1.0	0.9955408173624316	2	P19022	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.5721616420782495	0.1596680601943033	0.8731425623309543	1.0	0.9955408173624316	2	P50570	1
+Serpin, conserved site [IPR023795]	0.4252987483184312	0.1515755583033134	0.879521712278921	1.0	0.9955408173624316	3	P30740	1
+Actin, conserved site [IPR004001]	0.3856868246818937	0.0917775686773496	0.9268747664327284	1.0	0.9955408173624316	3	P42025	1
+Actin/actin-like conserved site [IPR020902]	0.3261725311599587	0.0829127120040515	0.933920946128722	1.0	0.9955408173624316	4	P42025	1
+Ubiquitin-activating enzyme E1, conserved site [IPR018074]	0.4714560615779263	0.0552813140149554	0.9559143486550836	1.0	0.9955408173624316	2	Q9UBT2	1
+Fumarate lyase, conserved site [IPR020557]	0.3970493906350178	0.0284562212817967	0.9772982842322342	1.0	0.9955408173624316	2	P07954	1
+Ribosomal protein S2, conserved site [IPR018130]	0.3909557408595215	0.0274026935529962	0.9781385499121072	1.0	0.9955408173624316	2	P08865	1
+Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]	0.3710711994868466	0.0247391442207212	0.9802630320531563	1.0	0.9955408173624316	2	O60573	1
+Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]	0.2993262752646732	0.0238059740814202	0.9810073747731992	1.0	0.9955408173624316	3	O00469,O60568	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPA, conserved site [IPR022658]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "Zinc finger, XPA-type, conserved site [IPR022652]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXK2", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "ITGAV", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASA1", "RBFA", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCAP", "SCD", "SCP2", "SDHB", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC2A8", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE1", "SYNE2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TLN2", "TMBIM6", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR7", "WDR77", "XPA", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ACTR1B", "ANKRD13A", "ANXA1", "ANXA2", "ANXA4", "CDH2", "CUL1", "CUL4B", "DNAJA3", "DNAJC2", "DNAJC21", "DNAJC9", "DNM2", "EEF1D", "EHHADH", "EIF4E2", "FH", "GGPS1", "HINT2", "HLA-B", "HMGB2", "HMOX2", "HSP90AA1", "HSP90AB1", "HSPA13", "HSPA14", "HSPA8", "LMNB1", "LMNB2", "MCM2", "MCM6", "NEFL", "OSBPL11", "OSBPL8", "PLOD2", "PLOD3", "PRKAR1A", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "RPSA", "SERPINB1", "STX10", "STX18", "STX7", "TSPAN3", "UBA2", "VCL", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "14-3-3 domain [IPR023410]", "1": "RNA recognition motif domain [IPR000504]", "2": "W2 domain [IPR003307]", "3": "Cullin protein, neddylation domain [IPR019559]", "4": "DnaJ domain [IPR001623]", "5": "SH3 domain [IPR001452]", "6": "K Homology domain, type 1 [IPR004088]", "7": "K Homology domain [IPR004087]", "8": "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "9": "TGS [IPR004095]", "10": "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "11": "P-type ATPase, haloacid dehalogenase domain [IPR044492]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:53f568a2fee2ae5ad0fbe39b36386f5704505da8f38344258bb7c93c0ff12183
+size 104340

interpro_domain/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Aminopeptidase N-like , N-terminal domain [IPR045357]	2	5	2.003058304941182	0.0451710306531605	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	1.0	0.0378187125466048	0.0024164244761899	0.0006770655215996	0.005094370489711
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	2	5	2.003058304941182	0.0451710306531605	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	1.0	0.0378187125466048	0.0024164244761899	0.0006770655215996	0.005094370489711

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3120,
+    "annotations_size": 2560,
+    "title": "Average number of proteins per term",
+    "value": 2.15859375
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C392/C392_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,235 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8223957730149196	2.003058304941182	0.0451710306531605	1.0	0.7981900787809445	5	P55786,Q9NZ08	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8223957730149196	2.003058304941182	0.0451710306531605	1.0	0.7981900787809445	5	P55786,Q9NZ08	2
+ERAP1-like C-terminal domain [IPR024571]	0.9695219762592222	2.0029391445238605	0.0451838208286141	1.0	0.7981900787809445	3	P55786,Q9NZ08	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8243497051696685	1.8495878931129843	0.0643729690993688	1.0	0.7981900787809445	4	Q9UMX5,O43169	2
+LEM domain [IPR003887]	0.7045269158467755	1.6614651446288833	0.0966200636266001	1.0	0.7981900787809445	6	P42167,P42166,Q8NC56	3
+Reticulon [IPR003388]	0.7711813418486112	1.6349970834624574	0.1020496590221955	1.0	0.7981900787809445	4	O75298	1
+14-3-3 domain [IPR023410]	0.6913937058445689	1.6029130993335974	0.1089538412185406	1.0	0.8014995216076557	6	P62258,P27348,P31946,P63104,P61981	5
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.759445916876907	1.5871766159421332	0.1124726493406191	1.0	0.8050756975841414	4	P21281	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.759445916876907	1.5871766159421332	0.1124726493406191	1.0	0.8050756975841414	4	P21281	1
+GINS subunit, domain A [IPR021151]	0.8451060601677354	1.5379322433620024	0.1240651825851921	1.0	0.8050756975841414	3	Q9Y248	1
+Zinc finger, RanBP2-type [IPR001876]	0.6729254960814617	1.4720636398601863	0.1410036930414691	1.0	0.814728753934328	8	Q92804,P35637,P98175	3
+Dynamin, N-terminal [IPR045063]	0.6603588199175519	1.463645914225446	0.1432907204742843	1.0	0.814728753934328	6	O60313,Q9H4M9	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6603588199175519	1.463645914225446	0.1432907204742843	1.0	0.814728753934328	6	O60313,Q9H4M9	2
+Cyclic nucleotide-binding domain [IPR000595]	0.6939649051000283	1.4611929740746925	0.1439624906375582	1.0	0.814728753934328	5	Q8IY17,P10644	2
+Gelsolin-like domain [IPR007123]	0.656449823573207	1.4460268795877416	0.1481696627488444	1.0	0.814728753934328	6	Q13045,O95486	2
+SWIRM domain [IPR007526]	0.7138170292760916	1.4000495676410163	0.1614984757080246	1.0	0.8408454452737881	4	Q8NB78,Q8TAQ2	2
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.9756254008980144	1.370852179363341	0.1704210411093232	1.0	0.8438156553533205	2	P98179	1
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.6975336935679748	1.3329415149733157	0.1825509973433896	1.0	0.8635246108994069	4	O60749	1
+CSN8/PSMD8/EIF3K [IPR033464]	0.7871998903218062	1.3176614566185314	0.1876170026272716	1.0	0.8635246108994069	3	Q99627	1
+GMP phosphodiesterase, delta subunit [IPR008015]	0.956061577934579	1.2994398617967533	0.1937930192666657	1.0	0.8655691829977644	2	O43924	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7789541225537413	1.286239366641582	0.1983595360791903	1.0	0.8655691829977644	3	P10321,P01889	2
+MHC class I-like antigen recognition-like [IPR011161]	0.7789541225537413	1.286239366641582	0.1983595360791903	1.0	0.8655691829977644	3	P10321,P01889	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7789541225537413	1.286239366641582	0.1983595360791903	1.0	0.8655691829977644	3	P10321,P01889	2
+Desmoplakin, spectrin-like domain [IPR041573]	0.682846909996088	1.2723412101096794	0.2032519124822531	1.0	0.8655691829977644	4	P15924,Q15149	2
+Desmoplakin, SH3 domain [IPR041615]	0.682846909996088	1.2723412101096794	0.2032519124822531	1.0	0.8655691829977644	4	P15924,Q15149	2
+Peptidase M16, C-terminal [IPR007863]	0.6181146666089983	1.2478820569016449	0.2120742525305232	1.0	0.8655691829977644	7	Q5JRX3,O43847,Q10713	3
+Peptidase M16, N-terminal [IPR011765]	0.6181146666089983	1.2478820569016449	0.2120742525305232	1.0	0.8655691829977644	7	Q5JRX3,O43847,Q10713	3
+Rho GTPase-activating protein domain [IPR000198]	0.676818875694354	1.247460942792821	0.2122285327267146	1.0	0.8655691829977644	4	O00459	1
+Lamin tail domain [IPR001322]	0.7686878408726342	1.2471280662670263	0.2123505433951638	1.0	0.8655691829977644	3	P20700,Q03252	2
+LEM-like domain [IPR013146]	0.9387427838357918	1.236389361741439	0.2163138685556158	1.0	0.8655691829977644	2	P42166	1
+SH2 domain [IPR000980]	0.633671171039096	1.2262392924925989	0.2201086389423157	1.0	0.8723052571148828	11	P46108,O00459	2
+OCRE domain [IPR041591]	0.7532711207710925	1.1884499001527775	0.2346562068576676	1.0	0.8953745753380621	3	P98175	1
+Intermediate filament, rod domain [IPR039008]	0.6033627417443349	1.1568586655992992	0.247330108689507	1.0	0.8970999989271196	8	P20700,P07196,Q03252	3
+Fibronectin type II domain [IPR000562]	0.7428809623973933	1.1489666212060974	0.2505697445452217	1.0	0.8970999989271196	3	Q9UBV2	1
+RNA recognition motif domain [IPR000504]	0.294884675409519	1.125566372754968	0.2603491084121039	1.0	0.9055621162160136	120	Q8WUA2,Q9Y6M1,O75494,P98179,Q16629,P23588,Q13243,O95319,Q96DH6,P49756,Q01844,P38159,Q8N684,Q9UKM9,Q9P2K5,Q5T8P6,Q86U42,Q9UHX1,P52272,P08579,Q92804,Q01085,P35637,P19338,Q13242,Q15056,Q99729,Q9Y580,Q9NTZ6,P09012,P22626,Q14011,Q9GZT3,P52756,P62995,Q86V81,O14979,Q08170,Q14103,Q13595,P05455,O75821,P07910,Q9BWF3,Q9NW64,Q07955,P26368,P33240,P98175	49
+PB1 domain [IPR000270]	0.9053880692751808	1.1156781434108891	0.2645599294999941	1.0	0.910313735913958	2	Q13501	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.6415083960756705	1.101888887348352	0.2705099803486841	1.0	0.9148025755516926	4	P07900,P08238	2
+Zinc finger, CCHC-type [IPR001878]	0.5712741842989371	1.0603466672564938	0.2889869157576901	1.0	0.9294051562056366	6	Q7Z6E9,Q16629,Q9BWF3	3
+Zinc finger, TFIIB-type [IPR013137]	0.8781270044900686	1.0180772107278422	0.3086412645535339	1.0	0.9486373419048012	2	Q00403	1
+Zinc finger, LIM-type [IPR001781]	0.5651354098875991	1.00798680782393	0.3134607954421295	1.0	0.9486373419048012	7	Q14847	1
+TATA box binding protein associated factor (TAF) [IPR004823]	0.8742783835792327	1.0043990042115107	0.3151863298084736	1.0	0.9486373419048012	2	Q9Y6J9	1
+Sec23/Sec24, helical domain [IPR006900]	0.5782833971623935	0.9625658878718352	0.3357654232175573	1.0	0.9491027134988376	5	O95486	1
+Sec23/Sec24 beta-sandwich [IPR012990]	0.5782833971623935	0.9625658878718352	0.3357654232175573	1.0	0.9491027134988376	5	O95486	1
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.5782833971623935	0.9625658878718352	0.3357654232175573	1.0	0.9491027134988376	5	O95486	1
+Sec23/Sec24, trunk domain [IPR006896]	0.5782833971623935	0.9625658878718352	0.3357654232175573	1.0	0.9491027134988376	5	O95486	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6913699069618089	0.9547624930004562	0.3396978188106598	1.0	0.9491027134988376	3	Q06323,Q9UL46	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6913699069618089	0.9547624930004562	0.3396978188106598	1.0	0.9491027134988376	3	Q06323,Q9UL46	2
+THIF-type NAD/FAD binding fold [IPR000594]	0.5501624945271353	0.9407194272201256	0.3468486605988308	1.0	0.9491027134988376	7	Q13564,Q9GZZ9	2
+MCM OB domain [IPR033762]	0.5441952304626884	0.9384827352446202	0.3479963853492287	1.0	0.9491027134988376	6	P49736,Q14566	2
+MCM N-terminal domain [IPR027925]	0.5441952304626884	0.9384827352446202	0.3479963853492287	1.0	0.9491027134988376	6	P49736,Q14566	2
+MCM domain [IPR001208]	0.5441952304626884	0.9384827352446202	0.3479963853492287	1.0	0.9491027134988376	6	P49736,Q14566	2
+MCM, AAA-lid domain [IPR041562]	0.5441952304626884	0.9384827352446202	0.3479963853492287	1.0	0.9491027134988376	6	P49736,Q14566	2
+RNA recognition motif domain, eukaryote [IPR003954]	0.5710820969512368	0.9211582225996632	0.3569678263206932	1.0	0.9577667859984808	12	P38159,Q14011,P19338	3
+ERM family, FERM domain C-lobe [IPR041789]	0.6817452678857899	0.9189197069969686	0.3581375712732249	1.0	0.9577667859984808	3	P35241,P26038	2
+Immunoglobulin C1-set [IPR003597]	0.5928197407513736	0.9031093283950667	0.3664678735925371	1.0	0.962680926511506	4	P10321,P01889	2
+Peptidase M20, dimerisation domain [IPR011650]	0.8428479794740211	0.8938775495160571	0.3713874109399322	1.0	0.962680926511506	2	Q96KP4	1
+PWI domain [IPR002483]	0.5620272322289394	0.8934152717856676	0.3716348272912531	1.0	0.962680926511506	5	O43395,Q8IYB3,Q5T8P6	3
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.5420836935443175	0.8808562062421158	0.3783956534586907	1.0	0.9669404837097492	8	Q16763,P61088	2
+Target SNARE coiled-coil homology domain [IPR000727]	0.5441125558154148	0.8667631086477198	0.3860718192532257	1.0	0.9711295613814436	9	O95721,O15400,O60499	3
+Syntaxin 6, N-terminal [IPR015260]	0.829698524695317	0.8483793590572002	0.3962267341142991	1.0	0.9801251235243578	2	O60499	1
+Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]	0.8220012828736369	0.8219854614125742	0.4110851714088714	1.0	0.9860885979397614	2	Q8WXI9	1
+WW domain [IPR001202]	0.5359351202511893	0.7864646700582884	0.4315953093177944	1.0	0.999122704635736	11	O75400,O60828,Q6ZWJ1,Q96PU5	4
+Chaperone DnaJ, C-terminal [IPR002939]	0.5328829422021432	0.7712290278197489	0.4405711913168084	1.0	0.999122704635736	5	Q96EY1	1
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.5062413187104875	0.7705291958284678	0.4409860432339267	1.0	0.999122704635736	6	Q13546	1
+HDGF-related, PWWP domain [IPR035496]	0.6316971446903922	0.7363492117841426	0.46151820443987	1.0	0.999122704635736	3	O75475,Q7Z4V5	2
+Peptidase M41 [IPR000642]	0.7931366260423339	0.7248347663479764	0.4685534044190707	1.0	0.999122704635736	2	Q9Y4W6	1
+W2 domain [IPR003307]	0.4951775085703804	0.699033929817956	0.4845308268235286	1.0	0.999122704635736	7	Q04637,Q9Y6E2,P55010,O43432,P78344	5
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.7799871712636355	0.681675975859388	0.4954438617405663	1.0	0.999122704635736	2	P10644	1
+GYF domain [IPR003169]	0.7780628608082092	0.675424736313055	0.4994059540528741	1.0	0.999122704635736	2	Q6Y7W6	1
+Zinc finger, CW-type [IPR011124]	0.7754971135343156	0.6671166054282158	0.5046976541330084	1.0	0.999122704635736	2	Q9Y6X9	1
+SMCs flexible hinge [IPR010935]	0.5055156110755132	0.6595186889128554	0.5095627490071166	1.0	0.999122704635736	5	Q9NTJ3,A6NHR9,Q9UQE7	3
+EH domain-containing protein, N-terminal [IPR031692]	0.7719692110327119	0.6557440471434605	0.5119888229393397	1.0	0.999122704635736	2	Q9H4M9	1
+Domain of unknown function DUF5600 [IPR040990]	0.7719692110327119	0.6557440471434605	0.5119888229393397	1.0	0.999122704635736	2	Q9H4M9	1
+Cullin homology domain [IPR016158]	0.4848402581422828	0.6550409859999696	0.5124413659561244	1.0	0.999122704635736	7	Q9UJX6	1
+Cullin, N-terminal [IPR001373]	0.4848402581422828	0.6550409859999696	0.5124413659561244	1.0	0.999122704635736	7	Q9UJX6	1
+UBX domain [IPR001012]	0.4786801167744384	0.6521391229411613	0.5143114276683498	1.0	0.999122704635736	6	Q9UNZ2	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.5282413350449378	0.6489921958013892	0.5163434205697832	1.0	0.999122704635736	4	Q15019,Q16181,Q9UHD8	3
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.6042292498522015	0.6399574889931865	0.5222002372099315	1.0	0.999122704635736	3	Q96F07	1
+Peptidase M28 [IPR007484]	0.6027625540286576	0.6349087719584264	0.525487915659945	1.0	0.999122704635736	3	P02786	1
+Anticodon-binding [IPR004154]	0.4745307708803865	0.6346747048911048	0.5256405944124487	1.0	0.999122704635736	6	P49590	1
+UAS [IPR006577]	0.5999358357394992	0.6252094973453614	0.5318335693961775	1.0	0.999122704635736	3	Q96CS3,Q9UNN5	2
+RNA binding activity-knot of a chromodomain [IPR025995]	0.7617062219371376	0.6230105579031023	0.5332775838261818	1.0	0.999122704635736	2	Q4LE39	1
+EB1, C-terminal [IPR004953]	0.7601026298909688	0.6179448135263148	0.5366117172485914	1.0	0.999122704635736	2	Q15555	1
+Plectin/S10, N-terminal [IPR005326]	0.7594611930725097	0.6159223233096509	0.5379457874362654	1.0	0.999122704635736	2	P46783	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.507631542797858	0.5719740012020132	0.5673395883069468	1.0	0.999122704635736	4	Q4J6C6	1
+IPT domain [IPR002909]	0.7415009621552502	0.5602179298638763	0.5753307986448404	1.0	0.999122704635736	2	Q96KP1	1
+SMARCC, C-terminal [IPR032451]	0.734765875561255	0.5398160745930228	0.5893238803123202	1.0	0.999122704635736	2	Q8TAQ2	1
+SMARCC, SWIRM-associated domain [IPR032448]	0.734765875561255	0.5398160745930228	0.5893238803123202	1.0	0.999122704635736	2	Q8TAQ2	1
+SMARCC, N-terminal [IPR032450]	0.734765875561255	0.5398160745930228	0.5893238803123202	1.0	0.999122704635736	2	Q8TAQ2	1
+Sec23, C-terminal [IPR037550]	0.7322001282873742	0.5321180204711937	0.594644257149678	1.0	0.999122704635736	2	Q15437	1
+MIT domain [IPR007330]	0.5701466683006078	0.5257357873977465	0.5990717949919877	1.0	0.999122704635736	3	Q9UN37	1
+Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]	0.7264271969211009	0.514951547684735	0.6065868784593043	1.0	0.999122704635736	2	Q13243	1
+CARG-binding factor, N-terminal [IPR012956]	0.7261064785118643	0.5140042232753427	0.6072490379652264	1.0	0.999122704635736	2	Q99729	1
+BAT2, N-terminal [IPR009738]	0.56199993162979	0.4995075598270757	0.6174218623496956	1.0	0.999122704635736	3	Q9Y520	1
+Chromo shadow domain [IPR008251]	0.5596440485456149	0.4920094761035987	0.6227126446132185	1.0	0.999122704635736	3	P45973	1
+Chromo domain subgroup [IPR017984]	0.5596440485456149	0.4920094761035987	0.6227126446132185	1.0	0.999122704635736	3	P45973	1
+ENTH  domain [IPR013809]	0.717767799871722	0.489615908780781	0.6244057168555284	1.0	0.999122704635736	2	Q14677	1
+U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]	0.7110327132777428	0.4702683292739851	0.6381633216311755	1.0	0.999122704635736	2	P09661	1
+Ataxin-2, C-terminal [IPR009818]	0.4767665794237123	0.462137227803875	0.6439829148900753	1.0	0.999122704635736	4	Q9BPZ3	1
+Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]	0.7075048107761673	0.4602633703172906	0.645327189854032	1.0	0.999122704635736	2	Q7Z4V5	1
+FCP1 homology domain [IPR004274]	0.7071840923669033	0.4593583287043883	0.6459768676461335	1.0	0.999122704635736	2	Q8WVY7	1
+Initiation factor eIF-4 gamma, MA3 [IPR003891]	0.4679165781394037	0.4321016862931078	0.6656675091487569	1.0	0.999122704635736	4	Q04637,O43432	2
+Cullin protein, neddylation domain [IPR019559]	0.4235709698137516	0.430930004530022	0.6665192659473718	1.0	0.999122704635736	6	Q13618,Q93034,Q13616,Q13620,Q13617	5
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.6962796664528514	0.4290449911172975	0.6678904831835331	1.0	0.999122704635736	2	Q96CP7	1
+PSI domain [IPR016201]	0.6937139191789577	0.4220448851942797	0.6729922555845493	1.0	0.999122704635736	2	O15031	1
+BAR domain [IPR004148]	0.4618100128369761	0.4118058013862312	0.6804817688527551	1.0	0.999122704635736	4	Q9NR46,Q99961,Q9Y371	3
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.5333289428527733	0.411143726529237	0.6809671485754862	1.0	0.999122704635736	3	Q08426	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.5333289428527733	0.411143726529237	0.6809671485754862	1.0	0.999122704635736	3	Q08426	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.4611681643132311	0.409693704987447	0.6820306484377139	1.0	0.999122704635736	4	O00303,P51665,O00487	3
+SUN coiled coil domain 2 [IPR040994]	0.6856959589480403	0.400506530280711	0.6887834746329187	1.0	0.999122704635736	2	O94901	1
+DNA2/NAM7 helicase, helicase domain [IPR041677]	0.4525463835378898	0.3817277349488184	0.7026633256492283	1.0	0.999122704635736	4	P51530,P42694	2
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.6783194355355974	0.3811551504448614	0.7030881263749369	1.0	0.999122704635736	2	P29692	1
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.6783194355355974	0.3811551504448614	0.7030881263749369	1.0	0.999122704635736	2	P29692	1
+Sirtuin family, catalytic core domain [IPR026590]	0.6779987171263595	0.3803241146255819	0.7037048371701271	1.0	0.999122704635736	2	Q8IXJ6	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.6683771648492719	0.3558034445822705	0.7219877692785981	1.0	0.999122704635736	2	P51114	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.6683771648492719	0.3558034445822705	0.7219877692785981	1.0	0.999122704635736	2	P51114	1
+Fxr1, tudor domain [IPR041560]	0.6683771648492719	0.3558034445822705	0.7219877692785981	1.0	0.999122704635736	2	P51114	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.6683771648492719	0.3558034445822705	0.7219877692785981	1.0	0.999122704635736	2	P51114	1
+Agenet-like domain [IPR008395]	0.6683771648492719	0.3558034445822705	0.7219877692785981	1.0	0.999122704635736	2	P51114	1
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.4218954960078824	0.3504734133006313	0.7259834395527012	1.0	0.999122704635736	5	P51530,P42694	2
+Proteasome component (PCI) domain [IPR000717]	0.461933327291648	0.3412587499579724	0.7329087987216396	1.0	0.999122704635736	19	O00231,Q9UBW8,Q13098,Q99627	4
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.4188463671705102	0.3405130051827857	0.7334702306041341	1.0	0.999122704635736	5	Q32P28	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.4188463671705102	0.3405130051827857	0.7334702306041341	1.0	0.999122704635736	5	Q32P28	1
+ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]	0.658755612572167	0.3320986928892823	0.7398147370977242	1.0	0.999122704635736	2	Q14240	1
+Band 7 domain [IPR001107]	0.4004966575098037	0.3282001332164045	0.7427603471257698	1.0	0.999122704635736	7	Q99623,P35232	2
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.4003074808584449	0.3275543683349409	0.7432486287621005	1.0	0.999122704635736	7	P25787,P60900	2
+Proteasomal ATPase OB C-terminal domain [IPR032501]	0.4148094414869196	0.3275037280433072	0.7432869237316932	1.0	0.999122704635736	5	P62191,P62333,P17980	3
+GAR domain [IPR003108]	0.6542655548428441	0.3213243746397506	0.7479645867220408	1.0	0.999122704635736	2	Q03001	1
+NECAP, PHear domain [IPR012466]	0.6536241180243723	0.3198004116205423	0.749119635561059	1.0	0.999122704635736	2	Q8NC96	1
+Linker histone H1/H5, domain H15 [IPR005818]	0.3923367244239693	0.3192516175139575	0.7495357180522431	1.0	0.999122704635736	6	Q92522,P16402	2
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.6427196921103365	0.2944860744383496	0.7683865028946097	1.0	0.999122704635736	2	Q8NF37	1
+LsmAD domain [IPR009604]	0.6420782552918497	0.2930323397010396	0.7694974326220005	1.0	0.999122704635736	2	Q99700	1
+Ataxin 2, SM domain [IPR025852]	0.6420782552918497	0.2930323397010396	0.7694974326220005	1.0	0.999122704635736	2	Q99700	1
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.4831568816169487	0.2743499793192188	0.7838156793881608	1.0	0.999122704635736	3	P18031,P10586	2
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.4831568816169487	0.2743499793192188	0.7838156793881608	1.0	0.999122704635736	3	P18031,P10586	2
+NOPS [IPR012975]	0.4805903111966693	0.2680575484207504	0.78865502179213	1.0	0.999122704635736	3	P23246,Q15233	2
+Legume-like lectin [IPR005052]	0.6305323925593285	0.2675522161521247	0.7890440162438479	1.0	0.999122704635736	2	P49257	1
+Arf GTPase activating protein [IPR001164]	0.6302116741500916	0.266863231657241	0.7895744671504881	1.0	0.999122704635736	2	Q8N6T3	1
+Chromo/chromo shadow domain [IPR000953]	0.3840960025349866	0.2569673936249645	0.7972039441633867	1.0	0.999122704635736	8	Q9HCK8,P45973,Q92922,Q8TAQ2	4
+Tyrosine-protein kinase, catalytic domain [IPR020635]	0.6199486850545174	0.2453621174041782	0.8061760585307876	1.0	0.999122704635736	2	Q15375	1
+FF domain [IPR002713]	0.6193072482360439	0.2440537773283978	0.8071891705558385	1.0	0.999122704635736	2	O75400	1
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.4700367651396554	0.2429732860244566	0.8080260920813811	1.0	0.999122704635736	3	Q10567	1
+DnaJ domain [IPR001623]	0.4279476176904754	0.2410983166657218	0.8094789174087089	1.0	0.999122704635736	18	Q8WXX5,Q5F1R6,O75937,Q99543,Q13217	5
+BZW1/2, W2 domain [IPR043510]	0.6119307248235999	0.2293115983503273	0.8186267394622881	1.0	0.999122704635736	2	Q9Y6E2	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.6007055805003155	0.2079617999868838	0.8352587944267325	1.0	0.999122704635736	2	O43390	1
+Sterol-sensing domain [IPR000731]	0.4512702314310944	0.2016190844649846	0.8402145243694084	1.0	0.999122704635736	3	O15118	1
+Armadillo repeat-containing domain [IPR006911]	0.588518280949321	0.1862832110433722	0.852222672672992	1.0	0.999122704635736	2	Q96D09	1
+EH domain [IPR000261]	0.3624883005924268	0.1795515302531129	0.8575046593871678	1.0	0.999122704635736	5	Q96D71,Q9H4M9	2
+Ricin B, lectin domain [IPR000772]	0.3770860077021944	0.1754436304666839	0.860731060043189	1.0	0.999122704635736	4	Q10471,Q10472,Q9UBG0	3
+Chromo domain [IPR023780]	0.3442497870606494	0.1749269501222282	0.8611370336248323	1.0	0.999122704635736	6	Q9HCK8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.5808210391276403	0.1734036662505651	0.8623341435097887	1.0	0.999122704635736	2	Q9BSJ8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.5808210391276403	0.1734036662505651	0.8623341435097887	1.0	0.999122704635736	2	Q9BSJ8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.5808210391276403	0.1734036662505651	0.8623341435097887	1.0	0.999122704635736	2	Q9BSJ8	1
+Synaptotagmin, SMP domain [IPR039010]	0.5808210391276403	0.1734036662505651	0.8623341435097887	1.0	0.999122704635736	2	Q9BSJ8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.5808210391276403	0.1734036662505651	0.8623341435097887	1.0	0.999122704635736	2	Q9BSJ8	1
+STAT transcription factor, all-alpha domain [IPR013800]	0.5805003207184036	0.172880703618814	0.862745199543351	1.0	0.999122704635736	2	P40763	1
+STAT transcription factor, protein interaction [IPR013799]	0.5805003207184036	0.172880703618814	0.862745199543351	1.0	0.999122704635736	2	P40763	1
+STAT transcription factor, DNA-binding [IPR013801]	0.5805003207184036	0.172880703618814	0.862745199543351	1.0	0.999122704635736	2	P40763	1
+EF-hand, Ca insensitive [IPR014837]	0.435996150144372	0.1711562401187491	0.8641009150137826	1.0	0.999122704635736	3	O43707,Q13813	2
+Cadherin-like [IPR002126]	0.5779345734445098	0.1687364335017501	0.86600395986813	1.0	0.999122704635736	2	P19022	1
+SH3 domain [IPR001452]	0.4753866689841188	0.1685702276561733	0.8661347002745803	1.0	0.999122704635736	40	Q9UQB8,Q14847,P15924,O00459,Q9H6R6,P46108,Q96PC5	7
+K Homology domain, type 1 [IPR004088]	0.4161085591812746	0.1678222857035913	0.8667230896935141	1.0	0.999122704635736	21	P51114,Q96AE4,Q96PU8,Q8IWZ3,Q13868,Q9Y6M1,Q96I24,Q00341,P61978	9
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.3525734631581771	0.1673499499841483	0.8670947038445691	1.0	0.999122704635736	8	Q96AY3,Q00688,Q02790	3
+Replication factor C, C-terminal [IPR013748]	0.4324671158164952	0.1645356580871454	0.869309478146286	1.0	0.999122704635736	3	P40937,P35249	2
+Phox homology [IPR001683]	0.356916710140999	0.1643972305183937	0.8694184436399759	1.0	0.999122704635736	9	Q9Y2I1,O60749,O60493	3
+Dynamin stalk domain [IPR000375]	0.5721616420782495	0.1596680601943033	0.8731425623309543	1.0	0.999122704635736	2	P50570	1
+Dynamin GTPase effector [IPR003130]	0.5721616420782495	0.1596680601943033	0.8731425623309543	1.0	0.999122704635736	2	P50570	1
+GTPase effector domain [IPR020850]	0.5721616420782495	0.1596680601943033	0.8731425623309543	1.0	0.999122704635736	2	P50570	1
+CID domain [IPR006569]	0.3350623721791679	0.1518339564137026	0.8793178992727455	1.0	0.999122704635736	6	Q5VT52,Q9NQG5	2
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.425409047160737	0.1517700053813879	0.8793683402757959	1.0	0.999122704635736	3	Q9NR33,Q01658	2
+Serpin domain [IPR023796]	0.4252987483184312	0.1515755583033134	0.879521712278921	1.0	0.999122704635736	3	P30740	1
+FERM, C-terminal PH-like domain [IPR018980]	0.3456870026932387	0.1500704614851044	0.8807090243543403	1.0	0.999122704635736	8	P35241	1
+FERM, N-terminal [IPR018979]	0.3456870026932387	0.1500704614851044	0.8807090243543403	1.0	0.999122704635736	8	P35241	1
+Sterile alpha motif domain [IPR001660]	0.3323188573413204	0.1452385807206286	0.8845225058529935	1.0	0.999122704635736	6	Q9Y3Z3,Q13136	2
+Spt5 C-terminal domain [IPR024945]	0.5590121872995496	0.1403330666206558	0.8883968394317683	1.0	0.999122704635736	2	Q9UQ35	1
+Alpha-D-phosphohexomutase, C-terminal [IPR005843]	0.5574085952533612	0.1381001089423893	0.8901612996783088	1.0	0.999122704635736	2	Q96G03	1
+DNA mismatch repair protein MutS, clamp [IPR007861]	0.5554842847979496	0.1354562154647396	0.8922511801245074	1.0	0.999122704635736	2	P43246	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.335326109014621	0.1198246249504401	0.904622074593517	1.0	0.999122704635736	5	P20020,P16615	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.335326109014621	0.1198246249504401	0.904622074593517	1.0	0.999122704635736	5	P20020,P16615	2
+Glycosyltransferase 2-like [IPR001173]	0.40359319858839	0.116340516545304	0.9073826760513736	1.0	0.999122704635736	3	Q10471,Q10472	2
+K Homology domain [IPR004087]	0.3890759007767955	0.1091153208950915	0.913111023130644	1.0	0.999122704635736	20	P51114,Q96AE4,Q96PU8,Q8IWZ3,P51116,Q9Y6M1,Q15637,Q96I24,Q00341,P61978	10
+Zinc finger, UBR-type [IPR003126]	0.3982259449822901	0.1085546965287823	0.9135556952531948	1.0	0.999122704635736	3	O95071	1
+LAIKA domain [IPR045353]	0.5333547145606089	0.1078093616164098	0.9141469166806284	1.0	0.999122704635736	2	Q8IX12	1
+S1-like RNA binding domain [IPR025223]	0.5333547145606089	0.1078093616164098	0.9141469166806284	1.0	0.999122704635736	2	Q8IX12	1
+BURAN domain [IPR045354]	0.5333547145606089	0.1078093616164098	0.9141469166806284	1.0	0.999122704635736	2	Q8IX12	1
+DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]	0.5333547145606089	0.1078093616164098	0.9141469166806284	1.0	0.999122704635736	2	Q8IX12	1
+SET domain [IPR001214]	0.3277688603531337	0.1054433736355692	0.9160240006850427	1.0	0.999122704635736	5	Q9H9B1,Q96KQ7,Q15047,O96028	4
+G-protein, beta subunit [IPR001632]	0.5311096856959521	0.1052831602302769	0.9161511248959208	1.0	0.999122704635736	2	Q9NVX2	1
+CAP Gly-rich domain [IPR000938]	0.3933269169072842	0.1017657961853172	0.9189425753501426	1.0	0.999122704635736	3	Q15813,Q14203	2
+SKP1 component, POZ domain [IPR016073]	0.526619627966639	0.1003810343829242	0.9200418260784752	1.0	0.999122704635736	2	Q15369	1
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.3111753371868916	0.0991525163645604	0.9210171754525318	1.0	0.999122704635736	6	P09234,Q15428,P43243,Q12874,Q9ULV3	5
+Choline/carnitine acyltransferase domain [IPR039551]	0.5205259781911411	0.0940444940481131	0.9250738121952436	1.0	0.999122704635736	2	P50416	1
+ELMO domain [IPR006816]	0.5166773572803007	0.0902271848179847	0.9281066820659244	1.0	0.999122704635736	2	Q96JJ3	1
+Domain of unknown function DUF4749 [IPR031847]	0.4958306606799179	0.0719382707831458	0.9426510332530322	1.0	0.999122704635736	2	O00151	1
+YTH domain [IPR007275]	0.4916613213598384	0.0687438488331162	0.9451935144160832	1.0	0.999122704635736	2	Q96MU7	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.4913406029506015	0.0685042544175571	0.9453842334986244	1.0	0.999122704635736	2	Q10471	1
+ZU5 domain [IPR000906]	0.4906991661321308	0.0680276683498733	0.94576360913859	1.0	0.999122704635736	2	Q12955	1
+Zinc finger, GATA-type [IPR000679]	0.3138605957555756	0.0665180282499194	0.9469654050282804	1.0	0.999122704635736	4	Q8WXI9	1
+HECT domain [IPR000569]	0.2950124491882021	0.0595854287045961	0.9524858239563532	1.0	0.999122704635736	7	Q96PU5	1
+TGS [IPR004095]	0.2942499196916228	0.0583819329181811	0.9534444056657652	1.0	0.999122704635736	7	Q9NTK5,A2RTX5,P26639,Q9NYK5,P55039,Q9Y295	6
+Myb domain [IPR017930]	0.2971479259395534	0.0532951680925254	0.9574967300358788	1.0	0.999122704635736	8	Q99543,Q8TAQ2	2
+SUN domain [IPR012919]	0.3435996150144398	0.0491805369254868	0.9607754217782274	1.0	0.999122704635736	3	Q9UH99,O94901	2
+NLE [IPR012972]	0.4583066067992257	0.0481789404552422	0.9615736337758888	1.0	0.999122704635736	2	Q9NVX2	1
+Copine, C2B domain [IPR037768]	0.4541372674791447	0.0461762398595642	0.963169780114479	1.0	0.999122704635736	2	Q99829	1
+Copine, C-terminal [IPR010734]	0.4541372674791447	0.0461762398595642	0.963169780114479	1.0	0.999122704635736	2	Q99829	1
+Leucine-rich repeat N-terminal domain [IPR000372]	0.4467607440667052	0.0429078921450831	0.965774957524254	1.0	0.999122704635736	2	O94813	1
+Cysteine-rich flanking region, C-terminal [IPR000483]	0.4467607440667052	0.0429078921450831	0.965774957524254	1.0	0.999122704635736	2	O94813	1
+Peptidase C2, calpain, domain III [IPR022683]	0.4361770365618895	0.038793387172746	0.969055117139265	1.0	0.999122704635736	2	P17655	1
+Peptidase C2, calpain, large subunit, domain III [IPR022682]	0.4361770365618895	0.038793387172746	0.969055117139265	1.0	0.999122704635736	2	P17655	1
+Peptidase C2, calpain, catalytic domain [IPR001300]	0.4361770365618895	0.038793387172746	0.969055117139265	1.0	0.999122704635736	2	P17655	1
+Calpain subdomain III [IPR033883]	0.4361770365618895	0.038793387172746	0.969055117139265	1.0	0.999122704635736	2	P17655	1
+Post-SET domain [IPR003616]	0.3275585498877119	0.0379725021682065	0.9697096063013836	1.0	0.999122704635736	3	O96028,Q15047	2
+Cyclin, C-terminal domain [IPR004367]	0.4204618345092966	0.0338061536109441	0.9730317288800208	1.0	0.999122704635736	2	P14635	1
+Cyclin, N-terminal [IPR006671]	0.4204618345092966	0.0338061536109441	0.9730317288800208	1.0	0.999122704635736	2	P14635	1
+Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]	0.42014111610006	0.0337170943102909	0.9731027474342964	1.0	0.999122704635736	2	P46926	1
+BAG domain [IPR003103]	0.4198203976908227	0.033628513718056	0.9731733844636796	1.0	0.999122704635736	2	Q9UL15	1
+Vps4 oligomerisation, C-terminal [IPR015415]	0.3172922682066094	0.0320606107036282	0.9744237153550424	1.0	0.999122704635736	3	Q9UN37,O75351	2
+Tim44-like domain [IPR007379]	0.4095574085952477	0.0310363017627663	0.9752405889883426	1.0	0.999122704635736	2	O43615	1
+Thioesterase domain [IPR006683]	0.4089159717767728	0.0308892141346067	0.9753578916937472	1.0	0.999122704635736	2	O00154	1
+Fumarate lyase, N-terminal [IPR022761]	0.3970493906350178	0.0284562212817967	0.9772982842322342	1.0	0.999122704635736	2	P07954	1
+Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]	0.2724060391904993	0.0283645830716932	0.9773713714430712	1.0	0.999122704635736	7	P41250,A2RTX5,P26639,Q9NP81,P07814,Q9BW92	6
+Ribosome receptor lysine/proline rich [IPR007794]	0.3912764592687573	0.0274550885509828	0.9780967604751296	1.0	0.999122704635736	2	Q86UP2	1
+Diaphanous autoregulatory (DAD) domain [IPR014767]	0.3036926456434973	0.0255855067602582	0.9795879462168012	1.0	0.999122704635736	3	O60879	1
+Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]	0.2993262752646732	0.0238059740814202	0.9810073747731992	1.0	0.999122704635736	3	O00469,O60568	2
+RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]	0.3579217447081411	0.0235104123881354	0.9812431328968424	1.0	0.999122704635736	2	Q96DH6	1
+RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]	0.3579217447081411	0.0235104123881354	0.9812431328968424	1.0	0.999122704635736	2	Q96DH6	1
+SAM domain [IPR041418]	0.3422065426555453	0.0224624969024208	0.9820790275827068	1.0	0.999122704635736	2	Q9NZI7	1
+CP2 transcription factor [IPR007604]	0.3422065426555453	0.0224624969024208	0.9820790275827068	1.0	0.999122704635736	2	Q9NZI7	1
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.3277742142398939	0.0218067158761491	0.9826021369674528	1.0	0.999122704635736	2	Q96CX2	1
+NSD, Cys-His rich domain [IPR041306]	0.3274534958306572	0.0217948348988303	0.982611614363376	1.0	0.999122704635736	2	O96028	1
+AWS domain [IPR006560]	0.3274534958306572	0.0217948348988303	0.982611614363376	1.0	0.999122704635736	2	O96028	1
+Ribosomal protein S10 domain [IPR027486]	0.3155869146888993	0.0214228406021114	0.982908353579654	1.0	0.999122704635736	2	Q96GC5	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.2699228791773819	0.0179205120915993	0.9857022653582724	1.0	0.9993654650761098	8	P16615,P23634,P98194,Q9HD20,P35670,P20020,P05023	7
+Glutathione S-transferase, N-terminal [IPR004045]	0.2601607421465331	0.0082537784609924	0.9934145123703412	1.0	1.0	8	P78417	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome B-type subunit [IPR023333]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome B-type subunit [IPR023333]", "1": "Proteasome, subunit alpha/beta [IPR001353]", "2": "14-3-3 protein [IPR000308]", "3": "P-type ATPase [IPR001757]"}