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interpro_active_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:9f0f435bdf67efd6347e6e5c7310bd8573281d89c8cf3c1006e5baec160dbaba
+size 82578

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3376,
+    "annotations_size": 56,
+    "title": "Average number of proteins per term",
+    "value": 2.6607142857142856
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C399/C399_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,8 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9789504891787728	1.6317163950083005	0.1027392446311337	0.9976908843688364	0.2361745559277334	3	P10619,Q9HB40	2
+Histidine acid phosphatase active site [IPR033379]	0.9419087136929462	1.6196238152594928	0.1053131105878883	0.9980340154273484	0.2361745559277334	2	Q9NPH0	1
+Tyrosine-protein kinase, active site [IPR008266]	0.6671125694196564	0.7686616304635693	0.4420942084363068	0.9999999999999936	0.6348019403187997	4	Q13308,Q15375	2
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.5428402016009561	0.1825972720594246	0.8551140249390619	1.0	0.9894787205273132	3	Q16881,P09622	2
+Nucleoside diphosphate kinase, active site [IPR023005]	0.5082987551867237	0.1352611220872397	0.8924054226129201	1.0	0.9894787205273132	2	P15531	1
+Peptidase S9, serine active site [IPR002471]	0.4502074688796698	0.0642948747374352	0.9487354343801048	1.0	0.9894787205273132	2	P48147	1
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.3971547125074115	0.0311336387321683	0.9751629628364727	1.0	0.9928931985244088	2	Q9NQ88	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CDC34", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CIT", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR14", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRKCA", "PRPF4B", "PTK2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["ACP6", "CTSA", "DLD", "EPHA7", "NME1", "PREP", "PTK7", "SCPEP1", "TIGAR", "TXNRD1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Protein kinase, ATP binding site [IPR017441]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:94a7ffc681685264fb4f277b59657c61f0a45763efc4b9329121c2f6cf9de36f
+size 76101

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3376,
+    "annotations_size": 29,
+    "title": "Average number of proteins per term",
+    "value": 5.137931034482759
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C399/C399_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,7 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4511633566587594	1.7918017160704056	0.0731647338454035	0.8895733338425702	0.3265389022609356	37	P0DP25,Q6NUK1,O43852,P80303,Q9BPX6,P42566,P41208,P07384,O75746,Q02818,O95202,Q9H4M9,Q9NWM8,Q96AY3,Q14257,Q9BRK5	16
+Beta tubulin, autoregulation binding site [IPR013838]	0.511888515706198	0.5358771617959552	0.5920434493914106	0.9999999999948972	0.8494521406503532	5	Q13885,P68371,P07437	3
+Peptidase M16, zinc-binding site [IPR001431]	0.4419561191042492	0.2891264169735571	0.7724846386523103	1.0	0.89608218083668	5	Q10713	1
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.4644339063426217	0.0779171688736387	0.9378939421442842	1.0	0.9647240629943614	2	Q9H0C8	1
+Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]	0.4262003556609385	0.0461534896522427	0.9631879128211924	1.0	0.9647240629943614	2	P50579	1
+Protein kinase, ATP binding site [IPR017441]	0.2481112547080075	0.0442262437925556	0.9647240629943614	1.0	0.9647240629943614	50	Q13464,Q99640,Q14012,P24941,P31751,P49841,P49840,Q13153,Q15375,Q7L7X3,Q13555	11

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ASPM", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHEK1", "CIT", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "P4HTM", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKACA", "PRKCA", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TAOK1", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["AKT2", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CDK2", "CETN2", "EHD1", "EPHA7", "EPS15", "FKBP10", "FKBP14", "GSK3A", "GSK3B", "ILKAP", "LETM1", "METAP2", "MICU1", "NUCB1", "NUCB2", "PAK1", "PKMYT1", "PMPCA", "RCN2", "ROCK1", "SDF4", "SLC25A12", "SLC25A24", "TAOK1", "TUBB", "TUBB2A", "TUBB4B"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Guanylate kinase, conserved site [IPR020590]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:0227feac8665f5582bb2adc3fb8691561f9859916cdf21defe1cf7156e98dc4d
+size 104605

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	4	8	2.3995657592139263	0.0164145312237624	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.001035282669561	1.0	1.0	1.828578586842436e-06	5.489393781591606e-05
+Syntaxin/epimorphin, conserved site [IPR006012]	3	8	2.2614045784375625	0.0237342155132598	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0023530800506003	0.0017062060788896	0.0066572828402184	0.003355333516566	0.0027834726260547

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3376,
+    "annotations_size": 281,
+    "title": "Average number of proteins per term",
+    "value": 2.7437722419928825
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C399/C399_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,30 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7971958226524422	2.3995657592139263	0.0164145312237624	0.990445648507956	0.0951832207567483	8	P20618,P28070,P49721,P28072	4
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7680694887806528	2.2614045784375625	0.0237342155132598	0.9988288101267192	0.1093330255610821	8	O43752,O60499,Q9P2W9	3
+Haem oxygenase conserved site [IPR018207]	0.990515708358032	1.817641678727881	0.0691189170075947	0.9999999981833488	0.2306709770292819	2	P09601	1
+Tetraspanin, conserved site [IPR018503]	0.9697688203912272	1.733297602487377	0.083042786691613	0.999999999973692	0.2651707165948098	2	O43657	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.6980225421302868	1.5693722644369852	0.1165612228305055	0.9999999999999992	0.3376670475811552	6	P33991,Q14566,P49736	3
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.6269306505025498	1.5612140077038243	0.1184732650170667	0.9999999999999996	0.3397039537734262	8	P30837,O94788,P51648	3
+Guanylate kinase, conserved site [IPR020590]	0.6878338278931682	1.5229073881410369	0.1277818771302485	1.0	0.3590670747359984	6	Q9NZW5,O14936,Q8N3R9,Q14168,Q12959	5
+ABC transporter-like, conserved site [IPR017871]	0.5501469237267991	1.476461231272099	0.1398201154449645	1.0	0.3777831965387984	12	P08183,O75027	2
+Sugar transporter, conserved site [IPR005829]	0.8770005927682282	1.354027340529337	0.1757276552474067	1.0	0.4331532554782569	2	Q7L0J3	1
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.5716271186529591	1.2752057351445223	0.2022364318955019	1.0	0.4815969268020003	8	O94788,P51648	2
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.7504075279888835	1.0870702695840735	0.2770057557755716	1.0	0.579074448380324	4	Q8N4Q0	1
+14-3-3 protein, conserved site [IPR023409]	0.5861172511577873	1.0540568609580423	0.2918568850535097	1.0	0.579074448380324	6	Q04917,P31946,P62258,P27348	4
+Dynamin, GTPase region, conserved site [IPR019762]	0.7519264967397754	0.8527350119740031	0.3938062702811691	1.0	0.6747534265183446	2	P50570	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.750444576170718	0.8470186257901392	0.3969847397610508	1.0	0.6760770416536684	2	P04066	1
+S100/Calbindin-D9k, conserved site [IPR001751]	0.7406639004149387	0.809502814951838	0.4182259843157494	1.0	0.6793150381082403	2	P60903	1
+Annexin repeat, conserved site [IPR018252]	0.5008022645003143	0.7767170466433682	0.4373257273031155	1.0	0.6873362066639164	7	P12429,P04083,P50995	3
+4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]	0.6885002963841148	0.61709582330583	0.5371715234328742	1.0	0.7662192796174501	2	P21912	1
+Tubulin, conserved site [IPR017975]	0.511888515706198	0.5358771617959552	0.5920434493914106	1.0	0.7998279292258962	5	Q13885,P68371,P07437	3
+Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]	0.6229994072317736	0.401753558322596	0.6878654039634307	1.0	0.8783763053440446	2	Q00796	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.610664308707875	0.3410463600658746	0.7330686813242191	1.0	0.9034749975969542	3	P09429	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.5376407824540619	0.1875453328278012	0.8512330837274809	1.0	0.9798227972210494	2	P06737	1
+DnaJ domain, conserved site [IPR018253]	0.3282232730831299	0.1867542697444497	0.8518533034547735	1.0	0.9798227972210494	11	Q96KC8,Q9Y2G8,Q9NVH1	3
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.2992171219891208	0.1080261079935617	0.913974982208575	1.0	1.0	13	Q9Y394,Q06136,Q53GQ0	3
+Ras GTPase-activating protein, conserved site [IPR023152]	0.4353499406880097	0.0951111159996916	0.924226568813822	1.0	1.0	4	Q13576,P20936,Q86VI3	3
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.4596484038504301	0.0585040273129901	0.9533471546595358	1.0	1.0	3	Q9H3P7	1
+Thiosulphate sulfurtransferase, conserved site [IPR001307]	0.4208654416123314	0.0428716078698283	0.965803881571704	1.0	1.0	2	Q16762	1
+Ribonuclease II/R, conserved site [IPR022966]	0.3781861292234754	0.0245972568703463	0.9803762073393404	1.0	1.0	2	Q8IYB7	1
+F-actin capping protein, alpha subunit, conserved site [IPR017865]	0.3722584469472455	0.0229847889332269	0.9816624064177916	1.0	1.0	2	P52907	1
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.4115031129558285	0.0203992531664069	0.9837248796141412	1.0	1.0	3	Q16539,P27361	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GPCR, family 2, secretin-like, conserved site [IPR017983]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubby, C-terminal, conserved site [IPR018066]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTBL2", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADGRL2", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DIS3L2", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "DYNLL2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "IVD", "KDM2A", "KDSR", "KIF11", "KIF13B", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NFKB1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RASA1", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF20", "RNF31", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCD5", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SORD", "SPAST", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STRN3", "STRN4", "STX10", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TULP3", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "UIMC1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ACBD3", "ALDH1A2", "ALDH1B1", "ALDH3A2", "ANXA1", "ANXA11", "ANXA3", "CAPZA1", "CASK", "DHRS7", "DIS3L2", "DLG1", "DNAJC1", "DNAJC11", "DNAJC16", "DNM2", "FUCA1", "HMGB1", "HMOX1", "HSD17B12", "IQGAP2", "IQGAP3", "KDSR", "MAPK14", "MAPK3", "MCM2", "MCM4", "MCM6", "MPP2", "MPP5", "MPP6", "PSMB1", "PSMB2", "PSMB4", "PSMB6", "PYGL", "RASA1", "S100A10", "SDHB", "SORD", "STX10", "STX18", "STX6", "SV2A", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB4B", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "GOLD domain [IPR009038]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "GOLD domain [IPR009038]", "2": "Dynamin, N-terminal [IPR045063]", "3": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "4": "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "5": "Guanylate kinase-like domain [IPR008144]", "6": "DnaJ domain [IPR001623]", "7": "WW domain [IPR001202]", "8": "TGS [IPR004095]", "9": "Ubiquitin-associated domain [IPR015940]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:6acb8d537248b58fa30b9b0eed63d91ab1ef0dca07f2cb78d869829efd0fb23f
+size 355962

interpro_domain/df_merge.tsv

@@ -0,0 +1,8 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-hand domain [IPR002048]	21	43	2.302887118314719	0.0212851951233863	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	0.1659667938931309	0.3837477700868037	0.6211264656767345	0.0343450359550879	0.0032674775078955
+ABC transporter type 1, transmembrane domain [IPR011527]	2	8	2.160686898479143	0.0307195336394459	2.3689320388349513	6.349514563106796	0.6640264147492347	0.3307390797434538	1.7803691733569	2.1393617497725477	1.1694677427725269	0.279101120079799	0.2770516275583917	1.0	1.0	0.307957256786686	0.0336357980244025
+GOLD domain [IPR009038]	5	6	2.1229630609427046	0.033756947368039	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	0.0303964749697605	0.0607401038440192	0.0066572828402184	0.0382400085743442	0.0002481332774246
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	2	6	2.0988874040764385	0.0358268274702042	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0117043378946798	1.0	1.0	0.0148625463558957	0.0053334351931861
+Aminopeptidase N-like , N-terminal domain [IPR045357]	2	6	2.0988874040764385	0.0358268274702042	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0117043378946798	1.0	1.0	0.0148625463558957	0.0053334351931861
+Band 7 domain [IPR001107]	1	8	2.0334404186414465	0.0420080473368693	3.825242718446602	7.354368932038835	0.2848798017769268	0.3662852929750465	1.8717479731706237	0.7075565364256523	1.25010454777189	0.3076860385713043	0.1768299998662401	1.0	1.0	0.1981219124770219	0.0677640175569944
+Major facilitator superfamily domain [IPR020846]	3	5	1.9624412576437544	0.04971113334105	1.8883495145631068	4.121359223300971	0.8776223597987594	0.2728824130413255	1.233496960525634	1.4580976091979958	1.2936014196902064	0.266909732326598	0.1341962448541644	1.0	1.0	0.1637924032376012	0.0557230881301947

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3376,
+    "annotations_size": 2722,
+    "title": "Average number of proteins per term",
+    "value": 2.1969140337986772
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C399/C399_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,197 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-hand domain [IPR002048]	0.482797132449518	2.302887118314719	0.0212851951233863	1.0	0.1290385325742931	43	Q6NUK1,P80303,Q9BPX6,P42566,P07384,O75746,P60660,Q96AY3,P41208,P12814,Q14257,P0DP25,Q6KCM7,Q8NF37,Q9NWM8,O43852,Q02818,O95202,Q9UJS0,Q9H4M9,Q9BRK5	21
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7471269806683547	2.160686898479143	0.0307195336394459	1.0	0.1575770065544479	8	P08183,O75027	2
+GOLD domain [IPR009038]	0.8225519287833702	2.1229630609427046	0.033756947368039	1.0	0.1676759319996391	6	Q15363,P49755,Q9BVK6,Q9H3P7,Q9Y3B3	5
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8169939607124705	2.0988874040764385	0.0358268274702042	1.0	0.1735309528054588	6	P55786,Q9NZ08	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8169939607124705	2.0988874040764385	0.0358268274702042	1.0	0.1735309528054588	6	P55786,Q9NZ08	2
+Band 7 domain [IPR001107]	0.7210025164576204	2.0334404186414465	0.0420080473368693	1.0	0.1835407782519396	8	P27105	1
+Major facilitator superfamily domain [IPR020846]	0.8527737316343609	1.9624412576437544	0.04971113334105	1.0	0.1964608692554087	5	Q7L0J3,Q9H2V7,P53985	3
+Cyclic nucleotide-binding domain [IPR000595]	0.8456358720198984	1.933142894793002	0.0532185971714154	1.0	0.20568907405176	5	P10644,Q6P4Q7	2
+Dynamin, N-terminal [IPR045063]	0.7176260220853524	1.8277263678456157	0.0675906287733261	1.0	0.2352707052698129	7	Q9H4M9,O60313,Q8IWA4,P50570,O95140	5
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.7176260220853524	1.8277263678456157	0.0675906287733261	1.0	0.2352707052698129	7	Q9H4M9,O60313,Q8IWA4,P50570,O95140	5
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9694724362774156	1.7320905718767736	0.0832574375837058	1.0	0.273373637036004	2	A6NIH7	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7312339587263048	1.7197391410234404	0.0854798695899203	1.0	0.2783208194064154	6	P05023,P16615,P35670,Q9HD20	4
+Polyketide synthase, enoylreductase domain [IPR020843]	0.6879276315312891	1.6867230369314088	0.0916566202857156	1.0	0.289766922668662	7	Q8N4Q0,Q14914	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7203462440401913	1.6706395850711508	0.0947928886624553	1.0	0.296241381101267	6	O15173,O43169	2
+Target SNARE coiled-coil homology domain [IPR000727]	0.5808642485846058	1.6570790640804824	0.0975034912677748	1.0	0.3016175146706676	12	O43752,O60499,Q13190,Q9UNK0	4
+LEM domain [IPR003887]	0.774063401815003	1.6351044140858282	0.1020271610049909	1.0	0.3087859902207664	5	P50402,P42167,Q86XL3	3
+Syntaxin 6, N-terminal [IPR015260]	0.9410195613515118	1.6159898704118132	0.106096503300529	1.0	0.3151521512380005	2	O60499	1
+CBS domain [IPR000644]	0.708258642947482	1.6159020548925516	0.1061154912817701	1.0	0.3151521512380005	6	P51798,Q6P4Q7,Q8NE01	3
+ERAP1-like C-terminal domain [IPR024571]	0.877443647641445	1.58320173331246	0.1133754915368365	1.0	0.323158198473968	4	P55786,Q9NZ08	2
+MCM, AAA-lid domain [IPR041562]	0.6980225421302868	1.5693722644369852	0.1165612228305055	1.0	0.3247397716460859	6	P33991,Q14566,P49736	3
+MCM domain [IPR001208]	0.6980225421302868	1.5693722644369852	0.1165612228305055	1.0	0.3247397716460859	6	P33991,Q14566,P49736	3
+MCM OB domain [IPR033762]	0.6980225421302868	1.5693722644369852	0.1165612228305055	1.0	0.3247397716460859	6	P33991,Q14566,P49736	3
+MCM N-terminal domain [IPR027925]	0.6980225421302868	1.5693722644369852	0.1165612228305055	1.0	0.3247397716460859	6	P33991,Q14566,P49736	3
+Sterol-sensing domain [IPR000731]	0.9229401304090102	1.5420434722776226	0.1230630299694137	1.0	0.3316609579967765	2	O15118	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9510821227394036	1.5273518261874477	0.1266735486390133	1.0	0.3371341174878588	3	Q15629,Q96CP7	2
+Ion transporter-like, CBS domain [IPR044751]	0.9113811499703616	1.4947285752735653	0.1349852934825073	1.0	0.3512714807451099	2	Q8NE01	1
+CNNM, transmembrane domain [IPR002550]	0.9113811499703616	1.4947285752735653	0.1349852934825073	1.0	0.3512714807451099	2	Q8NE01	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.5501469237267991	1.476461231272099	0.1398201154449645	1.0	0.3617779032710964	12	P08183,O75027	2
+Reticulon [IPR003388]	0.8444371724108317	1.4546084050324273	0.1457777028056963	1.0	0.3686683068879776	4	Q9NQC3,O95197	2
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.8924125666864258	1.417074875517777	0.1564610372945134	1.0	0.3804690608546042	2	P49841	1
+Modifier of rudimentary, Modr [IPR009851]	0.879964433906343	1.3661458533123132	0.1718931886489452	1.0	0.4029528711306077	2	A5D8V6	1
+Aldehyde dehydrogenase domain [IPR015590]	0.5617099995916796	1.3562445379549315	0.1750213755237273	1.0	0.4058209699985424	10	P30837,O94788,P51648	3
+DNA/RNA non-specific endonuclease [IPR001604]	0.8636633076467104	1.2995460626325552	0.1937565962956629	1.0	0.4285177393952202	2	O94919	1
+Extracellular Endonuclease, subunit A [IPR020821]	0.8636633076467104	1.2995460626325552	0.1937565962956629	1.0	0.4285177393952202	2	O94919	1
+Glycosyl transferase, family 1 [IPR001296]	0.8618850029638414	1.2922896936021284	0.1962568398145701	1.0	0.4322834409526042	2	Q9BT22	1
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.6354746140354633	1.2822330013895205	0.1997609227180143	1.0	0.4367463707939237	6	Q99536,Q8N4Q0,Q00796	3
+SET domain [IPR001214]	0.634923743365495	1.27968853481505	0.20065469845041	1.0	0.4383483861813934	6	O96028	1
+L27 domain [IPR004172]	0.6882230792049882	1.2697686829634265	0.2041670391575798	1.0	0.4449501045531884	5	Q9NZW5,Q8N3R9,Q14168,O14936	4
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8748372140828147	1.2410781875069583	0.2145768665601946	1.0	0.4565207629968342	3	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8748372140828147	1.2410781875069583	0.2145768665601946	1.0	0.4565207629968342	3	Q9Y282	1
+Immunoglobulin C1-set [IPR003597]	0.8482513337285125	1.2367365966995878	0.2161848874000438	1.0	0.4565207629968342	2	P04439	1
+MHC class I-like antigen recognition-like [IPR011161]	0.8482513337285125	1.2367365966995878	0.2161848874000438	1.0	0.4565207629968342	2	P04439	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.8482513337285125	1.2367365966995878	0.2161848874000438	1.0	0.4565207629968342	2	P04439	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.8482513337285125	1.2367365966995878	0.2161848874000438	1.0	0.4565207629968342	2	P04439	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.5632040586287418	1.2313085302999482	0.2182074926745638	1.0	0.4567187845675725	8	Q8TB36,P78417,Q9H7Z7	3
+Fibronectin type II domain [IPR000562]	0.8369887374036756	1.1909745698834548	0.2336635682180992	1.0	0.4692837119003933	2	Q9UBV2	1
+SUN coiled coil domain 2 [IPR040994]	0.8328393598103145	1.1741508019569569	0.2403346280146323	1.0	0.4768827421081325	2	Q9UH99	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.854575269608034	1.1652624731132064	0.2439127643950565	1.0	0.4818073618892189	3	Q13505	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.854575269608034	1.1652624731132064	0.2439127643950565	1.0	0.4818073618892189	3	Q13505	1
+LEM-like domain [IPR013146]	0.8109069353882639	1.0856268073685396	0.2776441346234983	1.0	0.5194139755636855	2	P42167	1
+CARG-binding factor, N-terminal [IPR012956]	0.8073503260225258	1.071346082376452	0.2840138466003949	1.0	0.5243742517418247	2	Q99729	1
+Phox homology [IPR001683]	0.5212957821701335	1.0690053289530446	0.2850672681798503	1.0	0.5257134850850627	9	Q9Y5X3,O60749,Q96L92	3
+FAD linked oxidase, N-terminal [IPR006094]	0.8058684054534683	1.0654027783389874	0.2866937000439176	1.0	0.5268498684945564	2	Q15392	1
+FAD-binding domain, PCMH-type [IPR016166]	0.8058684054534683	1.0654027783389874	0.2866937000439176	1.0	0.5268498684945564	2	Q15392	1
+Post-SET domain [IPR003616]	0.7440124192830416	1.062209446550188	0.2881406122901664	1.0	0.5278053476809105	4	O96028	1
+14-3-3 domain [IPR023410]	0.5861172511577873	1.0540568609580423	0.2918568850535097	1.0	0.5305385287677689	6	Q04917,P31946,P62258,P27348	4
+BTB/Kelch-associated [IPR011705]	0.8020154119739188	1.0499702767004295	0.2937317786765088	1.0	0.5323155136867224	2	Q08380	1
+BTB/POZ domain [IPR000210]	0.584873921043958	1.0483177425651444	0.2944922377618777	1.0	0.532629814742745	6	Q08380,Q96CX2,Q14145	3
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.8211371969383995	1.040954824209578	0.2978965153025421	1.0	0.5355840915809245	3	P61289	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.8211371969383995	1.040954824209578	0.2978965153025421	1.0	0.5355840915809245	3	P61289	1
+L27 domain, C-terminal [IPR014775]	0.7330960854092488	1.0198778246781128	0.3077864077010268	1.0	0.5429647451472425	4	Q8N3R9,Q14168,Q9NZW5	3
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.7273885280613333	0.997806232776814	0.3183733272626696	1.0	0.5527258782999127	4	Q9Y5X3	1
+Phospholipid/glycerol acyltransferase [IPR002123]	0.5448197773492529	0.989999287899668	0.3221744670826845	1.0	0.5536356688125423	7	Q9HCL2	1
+Glycosyl hydrolase, family 13, catalytic domain [IPR006047]	0.786603438055721	0.9885593873452668	0.3228787648082076	1.0	0.554033098224479	2	P08195	1
+Peptidase M16, C-terminal [IPR007863]	0.5431940813834081	0.9820546985376238	0.3260729016215675	1.0	0.5563231584187907	7	P22695,Q10713,Q5JRX3	3
+Peptidase M16, N-terminal [IPR011765]	0.5431940813834081	0.9820546985376238	0.3260729016215675	1.0	0.5563231584187907	7	P22695,Q10713,Q5JRX3	3
+Zinc finger, CHHC-type [IPR012996]	0.8016602431070323	0.9692522687843004	0.3324193378795095	1.0	0.5604246703234701	3	P31943,P55795	2
+Diacylglycerol kinase, catalytic domain [IPR001206]	0.7791938352104334	0.959238893567883	0.3374384111263508	1.0	0.5652352954374936	2	Q9NRA0	1
+CTP synthase GATase domain [IPR033828]	0.7762299940723185	0.9475518839259416	0.3433576311269584	1.0	0.5719561894901926	2	P17812	1
+CTP synthase, N-terminal [IPR017456]	0.7762299940723185	0.9475518839259416	0.3433576311269584	1.0	0.5719561894901926	2	P17812	1
+EYA domain, metazoan [IPR042577]	0.7691167753408426	0.9196059250549978	0.3577787293278678	1.0	0.5823108513908083	2	Q99504	1
+EYA domain [IPR006545]	0.7691167753408426	0.9196059250549978	0.3577787293278678	1.0	0.5823108513908083	2	Q99504	1
+Glutamine amidotransferase [IPR017926]	0.7050077765972625	0.9117671046089804	0.3618913304585009	1.0	0.5834952436658921	4	P49915,P17812	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7048182643977161	0.9110425645239886	0.3622729470225414	1.0	0.5834952436658921	4	P05023,P16615	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7048182643977161	0.9110425645239886	0.3622729470225414	1.0	0.5834952436658921	4	P05023,P16615	2
+Heat shock chaperonin-binding [IPR006636]	0.6038624073677221	0.9097123943145784	0.3629742059918714	1.0	0.5838804612462763	5	Q9BSL1	1
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.7787902705844161	0.8859933979541278	0.375621084829792	1.0	0.5906378538758986	3	Q96RL7	1
+Fzo/mitofusin HR2 domain [IPR006884]	0.759336099585063	0.8814360317441757	0.378081862633387	1.0	0.5928219067327647	2	O95140	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.4948913966971671	0.8754670200625946	0.3813198473425783	1.0	0.5945046211786922	8	O14936,Q9NZW5,Q8N3R9,Q14168,Q12959	5
+Guanylate kinase-like domain [IPR008144]	0.4948913966971671	0.8754670200625946	0.3813198473425783	1.0	0.5945046211786922	8	O14936,Q9NZW5,Q8N3R9,Q14168,Q12959	5
+MD-2-related lipid-recognition domain [IPR003172]	0.7572614107883824	0.8733802128578138	0.3824558725604048	1.0	0.5948940565168997	2	P17900	1
+Dynamin GTPase effector [IPR003130]	0.7519264967397754	0.8527350119740031	0.3938062702811691	1.0	0.6052742335998544	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.7519264967397754	0.8527350119740031	0.3938062702811691	1.0	0.6052742335998544	2	P50570	1
+GTPase effector domain [IPR020850]	0.7519264967397754	0.8527350119740031	0.3938062702811691	1.0	0.6052742335998544	2	P50570	1
+Legume-like lectin [IPR005052]	0.7513337285121526	0.8504474780888266	0.3950763492698954	1.0	0.6061994491052172	2	P49257	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.750444576170718	0.8470186257901392	0.3969847397610508	1.0	0.6065748246608479	2	P04066	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.4793131097659212	0.8439857481979872	0.3986773695932841	1.0	0.6069350112040937	9	Q9NWM8,O00170,Q96AY3	3
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.7465915826911684	0.8321948471827648	0.4052989719167428	1.0	0.6104651065933109	2	P98179	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7451096621221109	0.8265086772529923	0.4085155978149652	1.0	0.6135943579683387	2	O60506	1
+Peptidase M28 [IPR007484]	0.7611259323994767	0.8225624503765593	0.410756859350563	1.0	0.6137091721691994	3	P02786	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.7554467254936215	0.8023604778608836	0.4223444679246637	1.0	0.6231011608080947	3	Q7L576	1
+Dynamin, GTPase domain [IPR001401]	0.752149421879642	0.7906781605255957	0.4291318235569701	1.0	0.6290235992041318	3	O60313,P50570	2
+Sterile alpha motif domain [IPR001660]	0.4712978096475618	0.7543456425932363	0.4506417021853064	1.0	0.6486413878645011	8	Q6SZW1,Q6UWE0,Q15375,Q5PRF9	4
+Tim44-like domain [IPR007379]	0.7139893301719038	0.7093138300663078	0.4781297479032291	1.0	0.6689993463659359	2	O43615	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.7131001778304693	0.7060343842772662	0.4801667548428843	1.0	0.6695767964561122	2	Q96AE4	1
+OCRE domain [IPR041591]	0.7104327208061656	0.696221509979143	0.4862901189473396	1.0	0.6746512274046358	2	P98175	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.4575345684189036	0.6846908214652808	0.4935390421756689	1.0	0.6781879895755235	8	O95630,O15372	2
+AGC-kinase, C-terminal [IPR000961]	0.4217844970840271	0.6587338326513493	0.5100667032689727	1.0	0.6920935871989723	11	P31751	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.713632541453654	0.6571864686811356	0.5110610250807988	1.0	0.6920935871989723	3	P60903	1
+SUN domain [IPR012919]	0.7059494169729108	0.6313186640523136	0.5278321857590713	1.0	0.703603922446715	3	Q9UH99	1
+DnaJ domain [IPR001623]	0.3705267036027778	0.6142565060778115	0.5390458388455119	1.0	0.7134791205847882	19	Q96DA6,O14976,Q96KC8,Q9Y2G8,Q9NVH1,Q9UGP8	6
+EH domain [IPR000261]	0.6219342267834171	0.6045872829998424	0.545453258491138	1.0	0.7189534563061396	4	Q9H4M9	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.401916336134672	0.5962718463862703	0.5509936357420415	1.0	0.7224492661319061	12	Q9UHX1	1
+PTB/PI domain [IPR006020]	0.6928550252001315	0.5879182419127919	0.5565871715311315	1.0	0.726041879688812	3	Q9UKG1,O60343	2
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.4585806935785645	0.5788475843355124	0.5626920203025048	1.0	0.7297035156090605	7	Q8N4Q0	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.6898833045096142	0.5781968380171087	0.5631312333282283	1.0	0.7299253414854465	3	P23786	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.6763485477178433	0.5745778799656395	0.5655768155998226	1.0	0.731202398449765	2	Q9NVE7	1
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.6887044174325532	0.5743540605831512	0.565728233334021	1.0	0.731202398449765	3	Q16134,P21912	2
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.511888515706198	0.5358771617959552	0.5920434493914106	1.0	0.748849354006381	5	Q13885,P68371,P07437	3
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.511888515706198	0.5358771617959552	0.5920434493914106	1.0	0.748849354006381	5	Q13885,P68371,P07437	3
+Fatty acid desaturase domain [IPR005804]	0.6766255395783549	0.5354485444318758	0.5923397296694257	1.0	0.748849354006381	3	O15121	1
+Syntaxin, N-terminal domain [IPR006011]	0.599940688018982	0.5283739421845227	0.5972398197516751	1.0	0.748849354006381	4	Q13277,Q12846,Q86Y82	3
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.662418494368703	0.5271477720398103	0.5980909743070146	1.0	0.7495412670643158	2	O15460	1
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.670590643003618	0.5163448569100448	0.6056135720076976	1.0	0.7547152895396131	3	Q9NR33	1
+Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]	0.6570835803200961	0.5093823912918476	0.610484216547817	1.0	0.7574011109585953	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]	0.6570835803200961	0.5093823912918476	0.610484216547817	1.0	0.7574011109585953	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, central domain [IPR012000]	0.6570835803200961	0.5093823912918476	0.610484216547817	1.0	0.7574011109585953	2	A1L0T0	1
+Exportin-2, central domain [IPR013713]	0.6669250915907834	0.5048558847214019	0.6136600610077219	1.0	0.7589825004393865	3	O15397	1
+Tim10-like [IPR004217]	0.6661725466943422	0.5025081374015621	0.6153101297894481	1.0	0.7589825004393865	3	Q9Y5J9,Q9Y5L4	2
+Tyrosine-protein kinase, catalytic domain [IPR020635]	0.6653219883135346	0.4998591620129601	0.6171742492872514	1.0	0.7589825004393865	3	Q15375	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.654119739181981	0.4996132499276348	0.6173474263582825	1.0	0.7589825004393865	2	Q15067	1
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.3754596761234426	0.4488603096061638	0.6535324293944438	1.0	0.7771979208779853	12	P78417	1
+EH domain-containing protein, N-terminal [IPR031692]	0.6372258446947254	0.4453772398115434	0.6560471574618276	1.0	0.7772793866139621	2	Q9H4M9	1
+Domain of unknown function DUF5600 [IPR040990]	0.6372258446947254	0.4453772398115434	0.6560471574618276	1.0	0.7772793866139621	2	Q9H4M9	1
+Proteasomal ATPase OB C-terminal domain [IPR032501]	0.4867991693859473	0.4420974406199847	0.6584186963688512	1.0	0.7782091582787724	5	P62333,P62195,P43686,P17980	4
+Arfaptin homology (AH) domain [IPR010504]	0.6312981624184956	0.4269628708319548	0.669406371416899	1.0	0.7860759892134594	2	P53365	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.6406477995796145	0.425239860698263	0.6706618291053765	1.0	0.7864496672873141	3	P08243	1
+Armadillo repeat-containing domain [IPR006911]	0.6253704801422656	0.4088867680886723	0.682622759870821	1.0	0.7901037087840128	2	Q8N2F6	1
+Chromo shadow domain [IPR008251]	0.6222946931515005	0.3727907491874208	0.7093041884466105	1.0	0.8090126893495437	3	P83916,Q13185	2
+Chromo domain subgroup [IPR017984]	0.6222946931515005	0.3727907491874208	0.7093041884466105	1.0	0.8090126893495437	3	P83916,Q13185	2
+RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]	0.6120331950207482	0.3695101283420905	0.7117475251907455	1.0	0.8099401185490005	2	Q96DH6	1
+RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]	0.6120331950207482	0.3695101283420905	0.7117475251907455	1.0	0.8099401185490005	2	Q96DH6	1
+Replication factor C, C-terminal [IPR013748]	0.6187261450559971	0.3629227878133779	0.7166625634616595	1.0	0.8129545733251665	3	P35250	1
+WW domain [IPR001202]	0.3567181926278046	0.3497633650893686	0.7265162949334194	1.0	0.8212530543225779	12	P46934,Q96J02,O75400,Q13576,O95817,O14776,Q8N1G2,P46940,Q6ZWJ1,O60828,O00308	11
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.601327894603194	0.3164577382504751	0.7516550980753132	1.0	0.8433656953672722	3	Q96CX2	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.5234282325029537	0.2911304057684533	0.7709515861637697	1.0	0.8589972237158334	4	P51665,O00487,O00303	3
+Ras-associating (RA) domain [IPR000159]	0.5175797468519162	0.2752399241371347	0.7831319159941701	1.0	0.8690114453062091	4	Q96L92	1
+Zinc finger, RanBP2-type [IPR001876]	0.356942854979089	0.2703278465325415	0.7869080441318039	1.0	0.8714254256008016	10	Q96EP0,O95218,P35637,Q92804	4
+Ras GTPase-activating domain [IPR001936]	0.4354790863245422	0.2689196247886058	0.7879915346872464	1.0	0.8722704178197171	5	Q14C86,Q13576,P20936,Q86VI3	4
+TGS [IPR004095]	0.3739982190561004	0.228954734433025	0.8189040983145925	1.0	0.8970817306840841	7	Q9BW92,P55039,A2RTX5,Q9NTK5,Q9Y295,Q9NYK5	6
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.3726223991515306	0.2240591822230639	0.8227112528900988	1.0	0.899004428087856	7	P25786,P25787	2
+CAP Gly-rich domain [IPR000938]	0.4967378410438716	0.2217134090433148	0.8245369909849565	1.0	0.899915673400582	4	Q9NQT8,Q99426,Q14203	3
+Intermediate filament head, DNA-binding domain [IPR006821]	0.4898082018220479	0.2050397676329709	0.8375410549416185	1.0	0.9119147006204342	4	P08670	1
+BRO1 domain [IPR004328]	0.5382335506816851	0.1887192394139206	0.8503128716690682	1.0	0.9206649310593492	2	Q8WUM4	1
+Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]	0.5428402016009561	0.1825972720594246	0.8551140249390619	1.0	0.9251273354070456	3	Q16881,P09622	2
+GRAM domain [IPR004182]	0.5343805572021354	0.1811719377120191	0.8562326205466768	1.0	0.9259694847548884	2	Q66K14	1
+YTH domain [IPR007275]	0.47651399556635	0.1746970384628609	0.8613176949549028	1.0	0.9288854063657866	4	Q7Z739,Q96MU7	2
+VASP tetramerisation [IPR014885]	0.527563722584471	0.1683010996262399	0.8663464088261568	1.0	0.9324614174870696	2	P50552	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.5198577356253721	0.1544946058860544	0.8772197640389459	1.0	0.94118730694285	2	P51812	1
+PITH domain [IPR010400]	0.5174866627148801	0.1504050849625607	0.8804450296878183	1.0	0.9428642023528953	2	O43396	1
+MRH domain [IPR044865]	0.5244234408360389	0.1482662708206983	0.8821326331027011	1.0	0.94311848170155	3	P20645	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.5214942187963281	0.1431673101508001	0.8861580465454115	1.0	0.9451889508999256	3	Q9UHD8,Q9NVA2	2
+EF-hand, Ca insensitive [IPR014837]	0.5203083308627452	0.1411313595073089	0.8877661702812281	1.0	0.9461626920538382	3	P12814,O43707	2
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.5091879075281581	0.1366779661612411	0.89128534652132	1.0	0.9484279566970416	2	P51114	1
+Nucleoside diphosphate kinase-like domain [IPR034907]	0.5082987551867237	0.1352611220872397	0.8924054226129201	1.0	0.948877953262644	2	P15531	1
+SGNH hydrolase-type esterase domain [IPR013830]	0.5077059869591006	0.134322338002242	0.8931476901330111	1.0	0.949296373503341	2	P68402	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.4504744958481358	0.1217772815327841	0.9030754067306253	1.0	0.9569332560041222	4	Q4J6C6,P48147,Q86TI2	3
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.4504271059066763	0.121689018819572	0.9031453103139566	1.0	0.9569332560041222	4	Q9H3P7	1
+Copine, C-terminal [IPR010734]	0.4949614700652062	0.1152491825595645	0.9082476163121608	1.0	0.9608433780029934	2	O75131	1
+Copine, C2B domain [IPR037768]	0.4949614700652062	0.1152491825595645	0.9082476163121608	1.0	0.9608433780029934	2	O75131	1
+Anticodon-binding [IPR004154]	0.3737763274992691	0.1061702018709458	0.9154473127544036	1.0	0.9656774691974414	5	P07814,P41250,A2RTX5,Q9BW92	4
+Peptidase M16, middle/third domain [IPR032632]	0.4881446354475415	0.1059081415405849	0.9156552343859647	1.0	0.9656774691974414	2	O43847	1
+Thioredoxin-like fold [IPR012336]	0.4854771784232382	0.10241360304602	0.9184283867759044	1.0	0.9669948923460466	2	Q6DKJ4	1
+RuvB-like, AAA-lid domain [IPR041048]	0.4819205690575002	0.0978931351150582	0.9220171511896664	1.0	0.9675137569538442	2	Q9Y230	1
+TIP49, P-loop domain [IPR010339]	0.4819205690575002	0.0978931351150582	0.9220171511896664	1.0	0.9675137569538442	2	Q9Y230	1
+DNA mismatch repair protein MutS, clamp [IPR007861]	0.4611736810906955	0.0745936176930363	0.9405380523201576	1.0	0.9824039057618836	2	P43246	1
+FF domain [IPR002713]	0.4374629519857752	0.0539488467748272	0.956975919204102	1.0	0.9940009351049376	2	O14776	1
+Ku70/Ku80 C-terminal arm [IPR005160]	0.4359810314167177	0.0528532830652407	0.9578488070463818	1.0	0.9940009351049376	2	P12956	1
+Ku70/Ku80 beta-barrel domain [IPR006164]	0.4359810314167177	0.0528532830652407	0.9578488070463818	1.0	0.9940009351049376	2	P12956	1
+Ku70/Ku80, N-terminal alpha/beta [IPR005161]	0.4359810314167177	0.0528532830652407	0.9578488070463818	1.0	0.9940009351049376	2	P12956	1
+PIN domain [IPR002716]	0.4452475121241024	0.0447970515054753	0.9642690752930948	1.0	0.9983839497024222	3	Q9UPR3	1
+Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]	0.4146413752222901	0.0393561886065405	0.9686064092535096	1.0	1.0	2	Q9UID3	1
+I/LWEQ domain [IPR002558]	0.4084173088322485	0.0361609767265273	0.9711540016859443	1.0	1.0	2	Q9Y490	1
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.4322561517936554	0.0341870989365526	0.972727954085764	1.0	1.0	3	Q96EY1,O60884	2
+Gelsolin-like domain [IPR007123]	0.3146180225321594	0.0336115305229715	0.973186927436816	1.0	1.0	6	Q13045	1
+SKP1 component, POZ domain [IPR016073]	0.400414937759338	0.032493718865312	0.97407832500573	1.0	1.0	2	P63208	1
+tRNA-guanine(15) transglycosylase-like [IPR002616]	0.3930053349140504	0.0295087707667158	0.9764588239285816	1.0	1.0	2	Q9H974	1
+CTLH/CRA C-terminal to LisH motif domain [IPR024964]	0.3927089508002391	0.0293971286760788	0.9765478628010604	1.0	1.0	2	Q96S59	1
+CRA domain [IPR013144]	0.3927089508002391	0.0293971286760788	0.9765478628010604	1.0	1.0	2	Q96S59	1
+Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]	0.391523414344993	0.0289563281849303	0.9768994210351394	1.0	1.0	2	Q9Y678	1
+Coatomer subunit gamma, C-terminal [IPR032154]	0.391523414344993	0.0289563281849303	0.9768994210351394	1.0	1.0	2	Q9Y678	1
+RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]	0.3903378778897469	0.0285246616009695	0.9772436989163304	1.0	1.0	2	P61221	1
+Condensin complex subunit 1, C-terminal [IPR032682]	0.3838174273858941	0.0263081522056235	0.979011552643224	1.0	1.0	2	P42695	1
+GINS subunit, domain A [IPR021151]	0.3805572021339676	0.0252955928169462	0.9798191892304784	1.0	1.0	2	Q9BRT9	1
+Rrp44-like cold shock domain [IPR033771]	0.3781861292234754	0.0245972568703463	0.9803762073393404	1.0	1.0	2	Q8IYB7	1
+Dis3-like cold-shock domain 2 [IPR041505]	0.3781861292234754	0.0245972568703463	0.9803762073393404	1.0	1.0	2	Q8IYB7	1
+Ribonuclease II/R [IPR001900]	0.3781861292234754	0.0245972568703463	0.9803762073393404	1.0	1.0	2	Q8IYB7	1
+SGS domain [IPR007699]	0.3775933609958526	0.0244275489831164	0.980511573968082	1.0	1.0	2	Q9HB71	1
+Methylglyoxal synthase-like domain [IPR011607]	0.376111440426795	0.0240116472110583	0.9808433182553936	1.0	1.0	2	P31939	1
+B3/B4 tRNA-binding domain [IPR005146]	0.3695909899229424	0.0223183408843954	0.9821940186158468	1.0	1.0	2	Q9NSD9	1
+Formin, GTPase-binding domain [IPR010473]	0.4103172250222376	0.0197201067543345	0.9842666510275772	1.0	1.0	3	O60879,Q9NSV4	2
+Diaphanous autoregulatory (DAD) domain [IPR014767]	0.4103172250222376	0.0197201067543345	0.9842666510275772	1.0	1.0	3	O60879,Q9NSV4	2
+Formin, FH3 domain [IPR010472]	0.4103172250222376	0.0197201067543345	0.9842666510275772	1.0	1.0	3	O60879,Q9NSV4	2
+FCP1 homology domain [IPR004274]	0.3402489626556037	0.0170099837679964	0.9864286510298264	1.0	1.0	2	Q3ZCQ8	1
+Ubiquitin-associated domain [IPR015940]	0.2697340740439588	0.0145045949971396	0.9884274133722876	1.0	1.0	17	Q14157,Q9Y5A7,Q9BSL1,Q9UHD9,Q13501,Q96EP0	6
+Threonine-tRNA ligase catalytic core domain [IPR033728]	0.3735546990809379	0.0036478790988643	0.997089420042534	1.0	1.0	3	A2RTX5,Q9BW92	2

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Proteasome, subunit alpha/beta [IPR001353]"}